# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UBN2_3 PF14244.1 KII82604.1 - 0.0016 17.9 0.0 0.0043 16.6 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KII82604.1 - 0.014 14.8 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Chromo PF00385.19 KII82607.1 - 6.4e-13 48.1 0.0 6.9e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain hNIFK_binding PF12196.3 KII82610.1 - 1.5 8.2 5.4 3.6 7.0 3.8 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK DUF629 PF04780.7 KII82612.1 - 0.018 13.6 0.1 0.034 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Rpr2 PF04032.11 KII82612.1 - 0.073 12.9 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DDE_1 PF03184.14 KII82614.1 - 2.1e-32 112.0 0.0 1.1e-31 109.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KII82614.1 - 1.5e-06 27.9 0.9 1.5e-06 27.9 0.6 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 KII82614.1 - 0.00023 20.9 0.0 0.00065 19.4 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease RAP1 PF07218.6 KII82614.1 - 0.81 7.7 3.8 1.1 7.3 2.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sigma70_ner PF04546.8 KII82615.1 - 0.057 13.0 9.8 0.36 10.4 2.6 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 KII82615.1 - 1.4 7.2 8.2 1.7 6.9 5.7 1.3 1 0 0 1 1 1 0 Daxx Family TT_ORF2 PF02957.10 KII82615.1 - 9.2 6.9 9.4 28 5.4 6.5 1.8 1 0 0 1 1 1 0 TT viral ORF2 UBN2_2 PF14227.1 KII82618.1 - 1.1e-05 24.9 0.0 1.3e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII82618.1 - 2.6e-05 23.9 0.0 2.8e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HSP70 PF00012.15 KII82621.1 - 1.4e-29 102.5 0.0 1.7e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein adh_short PF00106.20 KII82622.1 - 2.1e-17 63.5 0.3 2.5e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII82622.1 - 1.9e-08 34.3 0.1 2.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII82622.1 - 8.9e-06 25.4 0.1 9.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII82623.1 - 0.005 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Amidase PF01425.16 KII82627.1 - 1.2e-58 199.0 0.2 1.5e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 Amidase ORC6 PF05460.8 KII82628.1 - 9.4 5.2 6.3 12 4.8 4.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) F-box-like PF12937.2 KII82629.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like Glyco_hyd_65N_2 PF14498.1 KII82631.1 - 0.053 13.2 1.1 0.063 12.9 0.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Spc7 PF08317.6 KII82631.1 - 0.098 11.2 8.5 0.12 10.9 5.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 KII82631.1 - 0.5 10.7 7.2 0.29 11.5 2.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SAP PF02037.22 KII82632.1 - 3.7e-06 26.3 0.0 1e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 SAP domain zf-B_box PF00643.19 KII82634.1 - 0.0074 16.1 8.8 0.017 14.9 6.1 1.6 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 KII82634.1 - 0.014 15.1 4.7 0.014 15.1 3.3 1.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF35_N PF12172.3 KII82634.1 - 0.026 14.4 6.0 0.026 14.4 4.2 2.8 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2457 PF10446.4 KII82636.1 - 1.9 7.1 5.4 1.9 7.1 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Corona_nucleoca PF00937.13 KII82636.1 - 4.3 6.1 5.9 4.3 6.1 4.1 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Integrase_1 PF12835.2 KII82637.1 - 0.064 13.0 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Integrase Ebola_NP PF05505.7 KII82640.1 - 0.64 8.0 2.6 0.7 7.8 1.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Helicase_C PF00271.26 KII82643.1 - 1e-15 57.3 0.0 2.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII82643.1 - 3.1e-12 46.3 0.0 6.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII82643.1 - 0.025 14.3 0.0 0.24 11.1 0.0 2.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KII82643.1 - 0.064 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF1264 PF06884.6 KII82643.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) Herpes_ORF11 PF04797.8 KII82645.1 - 0.18 10.1 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein adh_short PF00106.20 KII82646.1 - 2.7e-18 66.4 0.2 3.2e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII82646.1 - 3.7e-09 36.7 0.1 4.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII82646.1 - 7.3e-06 25.7 0.0 8.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII82647.1 - 1.1e-08 35.1 0.2 1.8e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII82647.1 - 0.011 15.4 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SR-25 PF10500.4 KII82650.1 - 0.0011 18.4 17.9 0.0027 17.1 12.4 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dsh_C PF12316.3 KII82650.1 - 0.38 10.8 9.9 0.037 14.1 3.7 1.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2201_N PF13203.1 KII82650.1 - 0.85 8.7 7.9 1.2 8.1 5.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain YL1 PF05764.8 KII82650.1 - 0.92 9.0 28.1 0.053 13.1 15.6 1.7 2 0 0 2 2 2 0 YL1 nuclear protein RR_TM4-6 PF06459.7 KII82650.1 - 4.3 7.1 12.7 7.1 6.4 8.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Shadoo PF14999.1 KII82652.1 - 0.063 13.1 2.9 0.14 12.0 2.0 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PhnA_Zn_Ribbon PF08274.7 KII82654.1 - 0.047 13.4 0.1 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon RFX5_DNA_bdg PF14621.1 KII82654.1 - 0.053 13.1 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 RFX5 DNA-binding domain Herpes_ORF11 PF04797.8 KII82658.1 - 0.043 12.2 0.0 0.059 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein RNA_pol PF00940.14 KII82659.1 - 3.7e-18 65.2 0.1 3.8e-18 65.1 0.1 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Ectatomin PF06457.6 KII82663.1 - 0.11 12.2 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ectatomin UBN2_2 PF14227.1 KII82665.1 - 5.4e-06 25.9 0.0 7.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII82665.1 - 0.00084 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type S-antigen PF05756.6 KII82670.1 - 0.75 9.8 3.5 1.7 8.7 2.4 1.5 1 0 0 1 1 1 0 S-antigen protein DUF2457 PF10446.4 KII82670.1 - 2.3 6.8 8.3 4 6.0 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3704 PF12488.3 KII82671.1 - 0.24 11.0 2.7 6.1 6.5 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3704) Rsc14 PF08586.5 KII82672.1 - 0.065 13.7 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit PT PF04886.7 KII82677.1 - 0.034 13.4 10.8 0.33 10.3 2.1 2.9 1 1 1 2 2 2 0 PT repeat Peptidase_C24 PF03510.9 KII82678.1 - 0.3 11.2 1.9 5.6 7.1 0.2 2.4 2 0 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family DUF3970 PF13113.1 KII82680.1 - 0.12 12.1 0.8 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) ESR1_C PF12743.2 KII82680.1 - 0.4 10.2 5.6 0.18 11.3 2.1 1.7 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Pox_A_type_inc PF04508.7 KII82681.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat adh_short_C2 PF13561.1 KII82683.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase IKI3 PF04762.7 KII82683.1 - 0.14 9.9 0.0 0.17 9.6 0.0 1.0 1 0 0 1 1 1 0 IKI3 family UBN2_3 PF14244.1 KII82684.1 - 0.00033 20.2 0.1 0.014 14.9 0.2 2.3 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII82684.1 - 0.0042 16.9 2.7 0.013 15.4 1.9 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KII82684.1 - 0.051 13.0 1.0 0.13 11.7 0.7 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3903 PF13043.1 KII82684.1 - 0.09 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) MtrH PF02007.13 KII82685.1 - 0.099 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit DDE_1 PF03184.14 KII82686.1 - 4.3e-05 22.7 0.0 4.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KII82686.1 - 0.005 16.6 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Gp_dh_N PF00044.19 KII82687.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Vps4_C PF09336.5 KII82687.1 - 0.095 12.6 1.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TniB PF05621.6 KII82692.1 - 0.058 12.1 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein zf-CCHC PF00098.18 KII82692.1 - 0.62 10.0 2.8 1.1 9.2 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.24 KII82699.1 - 2.5e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase CSTF_C PF14304.1 KII82701.1 - 0.0011 18.1 0.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 2 Transcription termination and cleavage factor C-terminal Exo_endo_phos_2 PF14529.1 KII82703.1 - 0.032 13.8 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF1248 PF06852.7 KII82703.1 - 0.072 12.3 0.4 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) Parathyroid PF01279.12 KII82703.1 - 0.21 12.2 2.2 17 6.1 0.6 2.4 2 0 0 2 2 2 0 Parathyroid hormone family Extensin_2 PF04554.8 KII82706.1 - 0.42 10.5 31.6 1.5e+04 -8.1 22.5 3.0 1 1 0 1 1 1 0 Extensin-like region zf-CCHC PF00098.18 KII82707.1 - 0.91 9.5 2.8 2 8.4 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 KII82707.1 - 1.2 9.4 3.5 8.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Glyco_transf_20 PF00982.16 KII82713.1 - 3.1e-11 42.4 0.0 3.9e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 UBN2_3 PF14244.1 KII82715.1 - 0.00034 20.1 0.0 0.0008 18.9 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KII82715.1 - 0.028 13.8 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DUF3847 PF12958.2 KII82717.1 - 8 6.2 7.0 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) BHD_1 PF10403.4 KII82718.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 1 Spermine_synth PF01564.12 KII82719.1 - 7.3e-92 306.7 0.0 8.7e-92 306.4 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KII82719.1 - 0.0001 21.9 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII82719.1 - 0.00018 22.0 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII82719.1 - 0.00043 20.2 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII82719.1 - 0.0028 18.0 0.0 0.0084 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII82719.1 - 0.0061 15.9 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KII82719.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase DUF43 PF01861.11 KII82719.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_11 PF08241.7 KII82719.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MIP-T3 PF10243.4 KII82721.1 - 0.014 13.9 7.4 0.019 13.4 5.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ABC_tran PF00005.22 KII82723.1 - 0.0027 18.0 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 KII82723.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Abhydrolase_4 PF08386.5 KII82730.1 - 7.9e-19 67.4 0.1 1.9e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KII82730.1 - 1.8e-15 57.1 0.0 3.4e-14 52.9 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII82730.1 - 1.1e-14 54.8 0.0 4.3e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII82730.1 - 0.0001 22.1 0.0 0.0012 18.6 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1325 PF07039.6 KII82734.1 - 0.08 12.5 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain GST_C_2 PF13410.1 KII82737.1 - 1.4e-06 28.0 0.9 4.7e-06 26.3 0.5 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII82737.1 - 0.00024 21.0 0.1 0.00087 19.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YopE_N PF09020.5 KII82737.1 - 0.014 15.4 1.2 0.078 13.0 0.5 2.1 2 0 0 2 2 2 0 YopE, N terminal UBN2_2 PF14227.1 KII82738.1 - 1.6e-15 56.6 0.0 1.8e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII82738.1 - 3.3e-14 52.6 0.1 3.6e-14 52.5 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RCC1 PF00415.13 KII82740.1 - 4.7e-49 164.3 25.0 7.9e-09 35.5 0.2 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII82740.1 - 5.6e-41 137.3 52.7 1.6e-07 30.7 0.3 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SPASM PF13186.1 KII82740.1 - 0.025 14.9 0.1 5.9 7.3 0.0 3.4 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain AvrE PF11725.3 KII82740.1 - 0.09 9.8 0.0 0.12 9.3 0.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor SUKH-3 PF14433.1 KII82740.1 - 0.09 12.5 1.1 26 4.5 0.0 3.6 4 0 0 4 4 4 0 SUKH-3 immunity protein Amidase02_C PF12123.3 KII82744.1 - 0.0038 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Nop52 PF05997.7 KII82744.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 DUF4219 PF13961.1 KII82746.1 - 0.067 12.6 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Amidase02_C PF12123.3 KII82747.1 - 0.0053 16.3 0.1 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Nop52 PF05997.7 KII82747.1 - 0.049 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Peptidase_C48 PF02902.14 KII82748.1 - 0.0026 17.4 0.1 0.0045 16.6 0.0 1.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain He_PIG_assoc PF10632.4 KII82750.1 - 0.35 10.2 1.8 2 7.8 0.1 2.6 3 0 0 3 3 3 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DUF1175 PF06672.6 KII82751.1 - 0.061 12.6 0.3 0.083 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) PBP1_TM PF14812.1 KII82754.1 - 0.0004 20.6 2.7 0.0004 20.6 1.9 2.1 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 KII82754.1 - 0.021 14.9 8.5 0.021 14.9 5.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) Myc_N PF01056.13 KII82754.1 - 0.047 12.8 7.9 0.063 12.4 5.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 KII82754.1 - 0.055 12.9 10.0 0.081 12.4 6.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 KII82754.1 - 0.31 10.2 10.0 0.45 9.7 7.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 KII82754.1 - 0.67 10.2 9.1 1.1 9.5 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.9 KII82754.1 - 0.99 8.8 9.2 0.07 12.6 1.5 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.11 KII82754.1 - 1.4 7.8 6.8 2.2 7.1 4.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 KII82754.1 - 1.4 8.9 19.0 0.064 13.3 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Sigma70_ner PF04546.8 KII82754.1 - 2 8.0 11.1 3.4 7.2 7.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.8 KII82754.1 - 2 7.9 17.2 0.22 11.0 6.1 2.1 2 0 0 2 2 2 0 YL1 nuclear protein FAM176 PF14851.1 KII82754.1 - 2.1 8.0 6.8 0.34 10.5 1.9 1.7 2 0 0 2 2 2 0 FAM176 family Radial_spoke PF04712.7 KII82754.1 - 2.5 6.7 9.6 3.8 6.1 6.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein RXT2_N PF08595.6 KII82754.1 - 3 7.6 9.1 5.3 6.8 6.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 KII82754.1 - 6.2 4.7 8.3 9 4.1 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 KII82754.1 - 7.5 5.1 10.8 12 4.4 7.5 1.3 1 0 0 1 1 1 0 Paf1 Pkinase_Tyr PF07714.12 KII82764.1 - 0.00038 19.6 0.0 0.0004 19.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII82764.1 - 0.022 13.9 0.0 0.024 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain HTH_29 PF13551.1 KII82766.1 - 3.8e-06 27.0 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 KII82766.1 - 0.026 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 KII82766.1 - 0.046 13.3 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain LELP1 PF15042.1 KII82767.1 - 0.7 10.0 4.6 1.1 9.4 3.2 1.2 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Chromo PF00385.19 KII82770.1 - 1.1e-12 47.4 0.0 1.1e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2625 PF10946.3 KII82775.1 - 0.034 13.0 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 PTN_MK_N PF05196.8 KII82776.1 - 0.018 15.0 5.5 0.037 13.9 3.8 1.5 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain COX1 PF00115.15 KII82777.1 - 6.8e-09 34.8 0.9 7.3e-09 34.7 0.6 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Jiraiya PF15038.1 KII82777.1 - 0.071 12.5 0.3 0.082 12.3 0.2 1.1 1 0 0 1 1 1 0 Jiraiya COX1 PF00115.15 KII82778.1 - 3.2e-26 91.9 4.9 3.6e-26 91.7 3.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Glycophorin_A PF01102.13 KII82778.1 - 0.73 9.6 4.1 4.2 7.1 0.2 2.1 2 0 0 2 2 2 0 Glycophorin A CZB PF13682.1 KII82780.1 - 0.084 13.0 0.4 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Transp_cyt_pur PF02133.10 KII82781.1 - 3.5e-10 39.0 0.5 5.3e-07 28.5 0.1 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2970 PF11174.3 KII82781.1 - 0.02 14.4 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF3635 PF12330.3 KII82783.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3635) JCAD PF15351.1 KII82783.1 - 3.1 5.2 8.3 4 4.9 5.8 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Dimer_Tnp_hAT PF05699.9 KII82784.1 - 2.7e-08 33.3 0.1 3.4e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVP PF00077.15 KII82795.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KII82795.1 - 0.052 14.0 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.5 KII82795.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 2 0 0 2 2 2 0 Aspartyl protease DUF3889 PF13028.1 KII82807.1 - 0.05 13.2 0.8 0.088 12.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) Alpha_GJ PF03229.8 KII82811.1 - 0.02 15.2 4.0 0.039 14.2 0.2 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J Oxidored_q1 PF00361.15 KII82812.1 - 2.4e-31 109.0 12.4 2.5e-31 108.9 8.6 1.0 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains zf-LITAF-like PF10601.4 KII82812.1 - 3.2 7.6 4.8 1.3 8.9 1.3 1.9 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain DUF4118 PF13493.1 KII82812.1 - 4 7.6 8.9 8 6.7 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) DAP_B PF07930.7 KII82814.1 - 0.072 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 D-aminopeptidase, domain B CENP-N PF05238.8 KII82814.1 - 0.18 10.7 3.5 0.21 10.6 1.3 1.6 1 1 1 2 2 2 0 Kinetochore protein CHL4 like LMBR1 PF04791.11 KII82814.1 - 0.19 10.2 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSase_L_chain PF00289.17 KII82816.1 - 1.1e-11 44.8 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KII82817.1 - 8.9e-17 61.0 0.0 6.5e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ACC_central PF08326.7 KII82817.1 - 1.6e-08 33.1 0.0 2.3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region DUF504 PF04457.7 KII82817.1 - 0.12 12.5 0.3 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF504) zf-RVT PF13966.1 KII82821.1 - 0.0026 18.0 0.5 0.0026 18.0 0.4 2.5 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 KII82822.1 - 1e-05 25.0 0.0 2.3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.1 KII82824.1 - 6.9e-19 67.9 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP-synt_C PF00137.16 KII82825.1 - 2.9e-18 65.5 13.4 3.6e-18 65.2 9.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit C DDE_1 PF03184.14 KII82826.1 - 4.3e-07 29.3 0.0 5.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FlgI PF02119.11 KII82827.1 - 0.17 10.4 1.5 0.48 9.0 0.5 1.8 1 1 1 2 2 2 0 Flagellar P-ring protein Helicase_C PF00271.26 KII82828.1 - 9.1e-15 54.2 0.0 1.7e-13 50.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII82828.1 - 4.4e-09 36.0 0.0 8.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rve_3 PF13683.1 KII82830.1 - 0.0099 15.3 0.2 0.065 12.7 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 KII82831.1 - 7.9e-15 54.2 0.1 8.5e-15 54.1 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ish1 PF10281.4 KII82834.1 - 0.0026 17.7 4.7 0.014 15.4 0.8 2.6 3 0 0 3 3 3 2 Putative stress-responsive nuclear envelope protein Extensin_2 PF04554.8 KII82836.1 - 0.42 10.5 31.6 1.5e+04 -8.1 22.5 3.0 1 1 0 1 1 1 0 Extensin-like region Helicase_C PF00271.26 KII82837.1 - 1.3e-12 47.3 0.0 2.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII82837.1 - 9.4e-08 31.7 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII82837.1 - 0.0048 16.7 0.2 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KII82837.1 - 0.053 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain T4SS-DNA_transf PF02534.9 KII82837.1 - 0.089 11.3 0.0 0.18 10.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer MMR_HSR1 PF01926.18 KII82840.1 - 4.5e-05 23.3 0.0 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KII82840.1 - 0.00063 19.3 2.0 0.031 13.8 0.0 2.4 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KII82840.1 - 0.00074 20.0 0.0 0.0072 16.8 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 KII82840.1 - 0.00091 20.0 0.0 0.0022 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 KII82840.1 - 0.0012 18.1 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MobB PF03205.9 KII82840.1 - 0.0018 18.0 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KII82840.1 - 0.0037 17.5 0.0 0.0074 16.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.4 KII82840.1 - 0.0053 16.2 0.0 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 KII82840.1 - 0.0062 15.2 0.0 1.1 7.9 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit AAA PF00004.24 KII82840.1 - 0.0066 16.6 0.1 0.12 12.6 0.0 2.5 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII82840.1 - 0.0073 16.4 0.1 0.044 13.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII82840.1 - 0.015 15.4 0.0 0.097 12.8 0.0 2.2 1 1 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.22 KII82840.1 - 0.015 14.7 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2326 PF10088.4 KII82840.1 - 0.027 14.0 0.7 0.099 12.2 0.0 2.1 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2326) SART-1 PF03343.8 KII82840.1 - 0.036 12.4 2.0 0.047 12.0 1.4 1.1 1 0 0 1 1 1 0 SART-1 family Arch_ATPase PF01637.13 KII82840.1 - 0.061 13.0 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 KII82840.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KII82840.1 - 0.2 10.9 1.5 0.42 9.8 0.0 2.2 3 0 0 3 3 3 0 Ferrous iron transport protein B UBN2_2 PF14227.1 KII82844.1 - 4.1e-11 42.4 0.0 6.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII82844.1 - 3e-08 33.4 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII82844.1 - 0.023 14.6 5.0 0.039 13.9 3.5 1.4 1 0 0 1 1 1 0 Zinc knuckle UBN2_3 PF14244.1 KII82844.1 - 0.11 12.0 0.1 3 7.3 0.1 2.1 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.1 KII82844.1 - 0.17 11.4 3.0 0.36 10.3 2.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Exo5 PF09810.4 KII82852.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DUF498 PF04430.9 KII82853.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF4140 PF13600.1 KII82853.1 - 0.06 13.8 4.3 0.13 12.7 3.0 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DDE_3 PF13358.1 KII82854.1 - 1.7e-11 44.1 0.0 5.3e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 KII82858.1 - 2.5e-07 30.2 0.1 2.9e-07 30.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.24 KII82860.1 - 3.7e-13 49.3 0.0 7.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII82860.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain ResIII PF04851.10 KII82860.1 - 0.014 15.2 0.0 0.075 12.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3505 PF12013.3 KII82861.1 - 8.9e-13 48.4 5.4 4e-12 46.3 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-Di19 PF05605.7 KII82861.1 - 3.5 7.8 11.9 10 6.3 1.4 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DNA_primase_S PF01896.14 KII82865.1 - 8.1e-29 100.2 0.0 1.2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit zf-RING_2 PF13639.1 KII82866.1 - 3e-07 30.1 9.7 4.6e-07 29.5 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII82866.1 - 9.6e-07 28.5 5.2 2e-06 27.5 3.6 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII82866.1 - 1.5e-06 27.7 7.3 3.3e-06 26.6 5.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII82866.1 - 2.8e-06 27.2 9.2 4.7e-06 26.5 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII82866.1 - 5.1e-06 26.0 5.5 8.3e-06 25.3 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII82866.1 - 8.2e-06 25.4 5.3 8.2e-06 25.4 3.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KII82866.1 - 0.00014 21.4 8.7 0.00025 20.7 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KII82866.1 - 0.15 12.0 6.7 0.43 10.5 4.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KII82866.1 - 7.1 6.2 7.4 0.74 9.4 1.7 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain LRR_6 PF13516.1 KII82867.1 - 0.0063 16.4 0.1 46 4.5 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 KII82867.1 - 0.21 11.9 3.2 38 5.1 0.0 4.9 6 0 0 6 6 6 0 Leucine rich repeat SURF4 PF02077.10 KII82869.1 - 4.5 6.5 0.0 7.3 5.8 0.0 1.2 1 0 0 1 1 1 0 SURF4 family Gp_dh_N PF00044.19 KII82871.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HMG_box PF00505.14 KII82872.1 - 0.19 11.9 9.2 0.35 11.1 3.6 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box NADH_dh_m_C1 PF15088.1 KII82874.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DNA_pol_A PF00476.15 KII82875.1 - 0.065 11.8 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family A zf-C2H2_4 PF13894.1 KII82877.1 - 4.1 7.9 6.8 30 5.2 0.8 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger CZB PF13682.1 KII82881.1 - 0.035 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Myb_DNA-binding PF00249.26 KII82883.1 - 0.021 14.8 0.0 0.43 10.6 0.0 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain GRP PF07172.6 KII82885.1 - 0.052 14.0 0.6 0.052 14.0 0.4 2.4 2 1 0 2 2 2 0 Glycine rich protein family Replicase PF03090.12 KII82887.1 - 0.13 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Replicase family fn1 PF00039.13 KII82888.1 - 0.11 12.2 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type I domain FYVE_2 PF02318.11 KII82889.1 - 0.035 13.9 3.2 0.078 12.8 2.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Tet_JBP PF12851.2 KII82893.1 - 1.4e-07 31.0 0.0 1.6e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily UBN2_2 PF14227.1 KII82896.1 - 0.0043 16.5 0.0 0.0081 15.7 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type RRP7 PF12923.2 KII82898.1 - 0.26 11.3 3.1 0.59 10.1 2.2 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) zf-MYND PF01753.13 KII82899.1 - 1.8e-08 34.0 10.8 2.9e-08 33.4 7.5 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KII82899.1 - 0.36 10.5 7.9 0.65 9.7 5.5 1.4 1 0 0 1 1 1 0 HIT zinc finger Zn_clus PF00172.13 KII82901.1 - 0.055 13.3 12.8 0.18 11.7 1.2 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_bd PF14376.1 KII82901.1 - 0.31 10.7 2.6 0.83 9.3 0.7 2.2 2 0 0 2 2 2 0 Haem-binding domain SET PF00856.23 KII82902.1 - 1.1e-10 42.0 0.0 2.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 SET domain IncA PF04156.9 KII82903.1 - 0.0012 18.5 0.4 0.0021 17.7 0.3 1.4 1 0 0 1 1 1 1 IncA protein DivIC PF04977.10 KII82903.1 - 0.0013 18.1 1.6 0.0034 16.8 1.1 1.7 1 0 0 1 1 1 1 Septum formation initiator Macoilin PF09726.4 KII82903.1 - 0.0044 15.3 7.4 0.0056 15.0 5.1 1.1 1 0 0 1 1 1 1 Transmembrane protein Taxilin PF09728.4 KII82903.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein V_ATPase_I PF01496.14 KII82903.1 - 0.014 13.2 0.1 0.019 12.8 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 KII82903.1 - 0.018 14.7 0.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Striatin PF08232.7 KII82903.1 - 0.024 14.9 0.2 0.024 14.9 0.2 2.2 2 1 0 2 2 2 0 Striatin family TSC22 PF01166.13 KII82903.1 - 0.024 14.5 0.8 2.8 7.9 0.2 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.6 KII82903.1 - 0.032 12.8 0.2 0.045 12.4 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2353 PF09789.4 KII82903.1 - 0.034 13.4 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.16 KII82903.1 - 0.035 14.0 0.9 0.85 9.6 0.3 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF4140 PF13600.1 KII82903.1 - 0.035 14.5 0.7 0.035 14.5 0.5 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 KII82903.1 - 0.036 13.9 1.1 0.036 13.9 0.7 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2205 PF10224.4 KII82903.1 - 0.047 13.2 0.9 0.12 11.9 0.6 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Fez1 PF06818.10 KII82903.1 - 0.05 13.6 1.0 0.1 12.5 0.7 1.5 1 0 0 1 1 1 0 Fez1 Filament PF00038.16 KII82903.1 - 0.053 12.9 2.4 0.097 12.1 1.5 1.4 1 1 0 1 1 1 0 Intermediate filament protein DUF904 PF06005.7 KII82903.1 - 0.06 13.6 2.2 0.15 12.3 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 KII82903.1 - 0.071 13.0 0.7 0.14 12.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 KII82903.1 - 0.075 12.8 0.2 0.075 12.8 0.2 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 KII82903.1 - 0.078 12.7 0.5 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 KII82903.1 - 0.2 11.5 1.1 0.42 10.5 0.3 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 KII82903.1 - 0.28 9.5 2.4 0.43 8.9 1.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 KII82904.1 - 0.015 14.5 8.7 1.3 8.1 2.9 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein HCMV_UL139 PF12507.3 KII82904.1 - 0.32 11.1 7.8 0.46 10.6 0.5 2.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Glutaredoxin PF00462.19 KII82907.1 - 0.058 13.3 0.9 0.8 9.7 0.0 2.9 3 0 0 3 3 3 0 Glutaredoxin PIF1 PF05970.9 KII82908.1 - 0.0013 17.7 2.6 0.19 10.6 0.5 2.9 1 1 1 2 2 2 2 PIF1-like helicase DUF3012 PF11216.3 KII82910.1 - 0.081 12.6 1.1 0.14 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Peptidase_C48 PF02902.14 KII82916.1 - 9.3e-06 25.4 1.5 0.00015 21.4 1.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.10 KII82917.1 - 0.00078 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cauli_VI PF01693.11 KII82919.1 - 2.2e-08 33.9 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin PAT1 PF09770.4 KII82922.1 - 2.3 6.3 8.0 2.6 6.1 5.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trypan_PARP PF05887.6 KII82926.1 - 1.5 8.6 5.0 2.6 7.8 3.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 KII82929.1 - 0.053 12.8 0.0 0.058 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) UBN2_2 PF14227.1 KII82930.1 - 3.5e-06 26.5 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII82930.1 - 6.7e-05 22.6 0.2 0.0001 22.0 0.0 1.3 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF2413 PF10310.4 KII82932.1 - 0.16 10.7 17.1 0.19 10.4 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TFIIA PF03153.8 KII82932.1 - 0.24 11.2 13.8 0.29 10.9 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit gag-asp_proteas PF13975.1 KII82933.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1510 PF07423.6 KII82933.1 - 0.49 9.7 0.0 0.49 9.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1510) Phe_tRNA-synt_N PF02912.13 KII82934.1 - 0.15 11.7 1.8 4.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Herpes_ORF11 PF04797.8 KII82938.1 - 0.0012 17.4 0.0 0.0017 16.8 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Chromo PF00385.19 KII82940.1 - 1.5e-12 47.0 0.0 1.7e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3678 PF12435.3 KII82942.1 - 3.6 7.2 8.9 12 5.5 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3678) SNF2_N PF00176.18 KII82945.1 - 2.3e-61 207.1 0.0 3.2e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KII82945.1 - 4e-07 30.0 0.0 8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KII82945.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KII82945.1 - 2.7e-05 23.7 4.6 7.4e-05 22.3 3.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII82945.1 - 5.5e-05 22.9 5.7 0.00013 21.7 3.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII82945.1 - 5.9e-05 22.6 5.7 0.00037 20.1 4.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII82945.1 - 0.00021 20.9 1.2 0.00021 20.9 0.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KII82945.1 - 0.0033 17.0 5.5 0.0091 15.6 3.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII82945.1 - 0.0036 17.2 5.5 0.0036 17.2 3.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KII82945.1 - 0.0054 16.2 1.8 0.016 14.7 1.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KII82945.1 - 0.013 15.3 5.5 0.013 15.3 3.8 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RLAN PF14401.1 KII82945.1 - 0.032 13.7 0.0 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain IBR PF01485.16 KII82945.1 - 0.24 11.3 2.9 0.34 10.8 0.4 2.2 2 0 0 2 2 2 0 IBR domain UBN2 PF14223.1 KII82946.1 - 0.033 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Neural_ProG_Cyt PF06567.6 KII82946.1 - 0.043 13.9 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Daxx PF03344.10 KII82947.1 - 0.00064 18.3 28.3 0.00091 17.8 19.6 1.4 1 0 0 1 1 1 1 Daxx Family Ycf1 PF05758.7 KII82947.1 - 0.63 7.6 9.1 0.8 7.3 6.3 1.2 1 0 0 1 1 1 0 Ycf1 DUF2457 PF10446.4 KII82947.1 - 8 5.0 47.7 0.052 12.2 27.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Fez1 PF06818.10 KII82948.1 - 0.0019 18.2 15.8 0.0019 18.2 11.0 2.5 1 1 1 2 2 2 1 Fez1 AAA_13 PF13166.1 KII82948.1 - 0.91 7.8 5.7 2.2 6.6 3.9 1.7 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 KII82948.1 - 1 8.5 13.6 7 5.7 0.2 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NP1-WLL PF11733.3 KII82950.1 - 3.4 7.9 9.1 9.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Non-capsid protein NP1 Ribosomal_L27e PF01777.13 KII82951.1 - 0.0049 16.9 1.1 0.0075 16.3 0.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family SNF2_N PF00176.18 KII82952.1 - 3.7e-15 55.5 0.0 6.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII82952.1 - 2.2e-11 43.4 0.0 4.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVP PF00077.15 KII82953.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_L27e PF01777.13 KII82955.1 - 8.8e-15 54.6 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family Dimer_Tnp_hAT PF05699.9 KII82957.1 - 6.3e-09 35.3 0.2 6.6e-09 35.2 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA_4 PF04326.9 KII82960.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Divergent AAA domain CDC45 PF02724.9 KII82960.1 - 1.4 6.8 3.4 2.2 6.2 2.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3505 PF12013.3 KII82961.1 - 0.0082 16.3 2.5 0.086 13.0 1.7 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3505) Dimer_Tnp_hAT PF05699.9 KII82962.1 - 5.1e-10 38.8 0.1 6.5e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UBN2_2 PF14227.1 KII82968.1 - 2.7e-06 26.9 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4186 PF13811.1 KII82977.1 - 0.043 13.5 1.8 5.1 6.8 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4186) DUF1639 PF07797.9 KII82979.1 - 0.0032 16.8 0.1 0.021 14.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1639) RVT_1 PF00078.22 KII82983.1 - 3.1e-06 26.7 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 KII82985.1 - 7.4e-06 26.1 0.4 2.6e-05 24.4 0.3 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase AT_hook PF02178.14 KII82986.1 - 0.39 10.5 6.0 1.4 8.7 4.2 2.0 1 0 0 1 1 1 0 AT hook motif SOBP PF15279.1 KII82988.1 - 0.14 12.5 4.5 0.18 12.1 3.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 KII82988.1 - 0.17 11.7 7.2 0.18 11.6 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 KII82988.1 - 1.2 8.9 7.2 1.4 8.6 5.0 1.1 1 0 0 1 1 1 0 DDHD domain BORG_CEP PF14957.1 KII82988.1 - 1.7 9.5 6.1 2.5 9.0 4.2 1.2 1 0 0 1 1 1 0 Cdc42 effector GBP_C PF02841.9 KII82988.1 - 1.8 7.7 11.7 2.2 7.3 8.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain eIF-3_zeta PF05091.7 KII82988.1 - 3 6.3 9.0 3.3 6.2 6.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNA_pol_Rpc4 PF05132.9 KII82988.1 - 4.6 7.2 9.5 6.3 6.7 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoVR PF04293.8 KII82988.1 - 5.2 5.3 6.4 6 5.1 4.4 1.0 1 0 0 1 1 1 0 SpoVR like protein NARP1 PF12569.3 KII82988.1 - 6.9 5.2 16.4 7.5 5.1 11.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Herpes_DNAp_acc PF04929.7 KII82988.1 - 9.5 5.0 10.6 11 4.8 7.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DEAD PF00270.24 KII82989.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase TFIIA PF03153.8 KII82990.1 - 0.0023 17.9 0.2 0.0023 17.9 0.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KII82990.1 - 0.032 13.4 7.5 0.045 13.0 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 KII82990.1 - 0.05 11.6 3.4 0.06 11.3 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KII82990.1 - 0.97 8.0 14.0 1.3 7.6 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 KII82990.1 - 5.9 5.2 11.1 7.9 4.8 7.7 1.1 1 0 0 1 1 1 0 Daxx Family Ank_5 PF13857.1 KII82991.1 - 0.099 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.26 KII82992.1 - 0.0011 18.9 0.1 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.20 KII82993.1 - 1.2e-21 77.0 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII82993.1 - 0.12 11.4 0.0 0.35 9.9 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Herpes_TAF50 PF03326.8 KII82996.1 - 1.6 7.5 12.4 2.4 7.0 8.6 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PGA2 PF07543.7 KII82997.1 - 0.054 13.2 8.0 0.089 12.5 5.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 PIF1 PF05970.9 KII83001.1 - 0.00023 20.2 0.1 0.0024 16.8 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 KII83002.1 - 1.4e-05 24.2 0.6 1.4e-05 24.2 0.4 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KII83002.1 - 0.0027 17.3 0.0 0.0027 17.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KII83002.1 - 0.0052 16.3 0.1 0.0052 16.3 0.1 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KII83002.1 - 0.069 12.9 0.3 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KII83002.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KII83002.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.0 1 0 0 1 1 1 0 AAA domain Cbl_N2 PF02761.9 KII83003.1 - 0.098 12.7 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain F-box PF00646.28 KII83005.1 - 0.014 15.0 2.4 0.28 10.9 0.0 3.0 2 0 0 2 2 2 0 F-box domain ELYS PF13934.1 KII83009.1 - 0.079 12.6 0.0 0.09 12.4 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore complex assembly PHD PF00628.24 KII83013.1 - 2.4 7.9 6.3 5.9 6.6 4.4 1.6 1 1 0 1 1 1 0 PHD-finger BRF1 PF07741.8 KII83015.1 - 0.052 13.7 0.7 0.18 12.0 0.5 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2201_N PF13203.1 KII83015.1 - 0.12 11.5 5.3 0.3 10.2 0.0 2.9 2 1 1 3 3 3 0 Putative metallopeptidase domain DEAD PF00270.24 KII83016.1 - 2.9e-08 33.3 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 KII83016.1 - 1.3e-07 31.8 1.1 4e-07 30.2 0.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Helicase_C PF00271.26 KII83016.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII83016.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_15 PF00723.16 KII83020.1 - 5.9e-89 298.6 0.1 7e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KII83020.1 - 6.3e-29 99.4 0.4 1.4e-28 98.2 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain zf-CCCH PF00642.19 KII83021.1 - 4.5e-13 48.5 18.6 6.4e-06 25.7 0.2 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII83021.1 - 0.49 10.4 20.7 0.45 10.5 1.3 3.9 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type BTB PF00651.26 KII83022.1 - 2.4e-05 24.3 0.0 0.62 10.0 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain FAD_binding_2 PF00890.19 KII83023.1 - 2.5e-42 145.2 4.3 3.8e-37 128.1 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KII83023.1 - 6e-07 29.5 0.2 0.0066 16.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII83023.1 - 2.3e-06 26.7 6.2 1.5e-05 24.0 4.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KII83023.1 - 2.5e-06 26.8 2.3 5e-05 22.5 1.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KII83023.1 - 0.00069 18.5 0.4 0.00069 18.5 0.3 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KII83023.1 - 0.001 19.1 0.1 0.14 12.2 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII83023.1 - 0.0019 18.1 1.6 0.0045 16.9 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KII83023.1 - 0.0022 16.5 1.8 0.22 9.9 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.7 KII83023.1 - 0.077 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.17 KII83024.1 - 2e-70 237.6 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KII83025.1 - 2.9e-18 66.3 0.4 9.8e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KII83025.1 - 1.7e-16 60.7 0.8 4.7e-15 56.0 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII83025.1 - 5.9e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII83025.1 - 0.0055 16.7 0.2 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KII83025.1 - 0.022 14.8 0.3 0.039 14.0 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.2 KII83026.1 - 5e-12 45.3 0.7 1.7e-11 43.6 0.5 2.0 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.17 KII83027.1 - 4.5e-49 163.9 0.4 1.9e-17 62.6 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII83027.1 - 9.2e-39 131.2 0.1 8e-12 44.9 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII83027.1 - 1.1e-17 63.6 0.1 4.8e-05 23.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KII83027.1 - 0.0015 18.2 0.0 1.4 8.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TENA_THI-4 PF03070.11 KII83028.1 - 3.8e-43 147.6 0.0 4.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family BioT2 PF15368.1 KII83028.1 - 0.15 11.7 0.1 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 p450 PF00067.17 KII83030.1 - 1.7e-67 227.9 0.0 2.1e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MRP-L47 PF06984.8 KII83031.1 - 2e-22 78.8 0.0 4.7e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 KII83031.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.9 3 0 0 3 3 3 0 Ribosomal L29 protein Complex1_LYR PF05347.10 KII83032.1 - 8.5e-08 31.8 0.5 1.5e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII83032.1 - 1e-06 28.8 0.4 1.4e-06 28.3 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like YrbL-PhoP_reg PF10707.4 KII83033.1 - 0.037 13.3 0.1 0.18 11.1 0.1 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Asp PF00026.18 KII83036.1 - 1.8e-07 30.6 0.0 0.01 15.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Salt_tol_Pase PF09506.5 KII83036.1 - 3.5e-05 22.5 0.0 0.15 10.5 0.0 2.1 2 0 0 2 2 2 2 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Asp PF00026.18 KII83037.1 - 2.9e-17 62.9 4.2 3.6e-17 62.6 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII83037.1 - 0.0014 19.0 0.6 0.0035 17.8 0.4 1.6 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KII83037.1 - 0.004 16.9 0.1 0.0071 16.1 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tyrosinase PF00264.15 KII83039.1 - 2.9e-47 161.6 1.4 3.9e-47 161.2 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Cas_Cas6 PF01881.11 KII83042.1 - 0.006 16.8 0.0 0.0078 16.4 0.0 1.0 1 0 0 1 1 1 1 CRISPR associated protein Cas6 Glyco_hydro_38C PF07748.8 KII83045.1 - 0.042 12.6 0.0 0.055 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain zf-B_box PF00643.19 KII83049.1 - 0.0034 17.2 7.8 0.0097 15.7 5.4 1.8 1 0 0 1 1 1 1 B-box zinc finger Cauli_VI PF01693.11 KII83051.1 - 5e-14 52.0 1.9 1.6e-09 37.6 0.4 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin Attacin_N PF03768.10 KII83054.1 - 3.6 7.5 12.7 0.77 9.6 0.9 2.9 1 1 2 3 3 3 0 Attacin, N-terminal region S-antigen PF05756.6 KII83055.1 - 0.46 10.4 3.9 0.81 9.7 2.7 1.3 1 0 0 1 1 1 0 S-antigen protein DUF1900 PF08954.6 KII83058.1 - 5.5e-47 158.7 0.0 1.2e-46 157.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KII83058.1 - 8.5e-28 95.7 0.1 1.5e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KII83058.1 - 3.7e-23 80.5 1.6 7.4e-08 31.9 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4201 PF13870.1 KII83058.1 - 0.061 12.7 0.6 0.09 12.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 KII83058.1 - 0.11 12.1 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 KII83058.1 - 0.14 11.5 0.6 0.23 10.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF904 PF06005.7 KII83058.1 - 0.24 11.7 2.0 0.42 10.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KII83058.1 - 0.27 11.0 3.9 0.44 10.3 2.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GcrA PF07750.6 KII83059.1 - 0.029 14.5 1.2 0.029 14.5 0.8 2.8 2 1 0 2 2 2 0 GcrA cell cycle regulator Nop14 PF04147.7 KII83059.1 - 7 4.4 18.9 0.62 7.9 9.9 1.5 2 0 0 2 2 2 0 Nop14-like family TFIIA PF03153.8 KII83060.1 - 0.12 12.2 6.7 0.13 12.0 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KII83060.1 - 4.2 5.1 15.3 5 4.9 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M28 PF04389.12 KII83063.1 - 2.8e-30 105.3 0.1 5e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KII83063.1 - 3.3e-05 23.4 0.0 7.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cu-oxidase PF00394.17 KII83064.1 - 1.3e-48 164.9 0.0 7.6e-47 159.1 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KII83064.1 - 7.3e-41 138.5 2.6 1.4e-39 134.4 0.2 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KII83064.1 - 2.1e-33 114.7 6.3 2.9e-31 107.8 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase RRM_6 PF14259.1 KII83065.1 - 2.8e-06 27.2 0.0 5.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII83065.1 - 9e-05 22.0 0.0 0.00026 20.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII83065.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCC1 PF00415.13 KII83066.1 - 1e-19 70.4 0.7 0.00037 20.6 0.2 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KII83066.1 - 2.4e-13 50.0 0.0 9.2e-06 25.6 0.0 3.0 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KII83066.1 - 1.5e-09 38.0 0.4 3.9e-05 24.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KII83066.1 - 1.3e-07 31.0 0.1 1.3e-07 31.0 0.1 5.2 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 KII83066.1 - 4.2e-07 30.1 0.1 9e-06 25.9 0.1 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KII83066.1 - 1.7e-05 24.3 0.4 0.011 15.4 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KII83066.1 - 1.8e-05 24.5 0.2 0.012 15.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KII83066.1 - 1.8e-05 24.7 0.8 0.11 12.8 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Auxin_inducible PF02519.9 KII83067.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Auxin responsive protein ADH_zinc_N PF00107.21 KII83068.1 - 1e-10 41.2 0.7 1.8e-10 40.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII83068.1 - 3.1e-08 33.3 0.4 1.2e-07 31.4 0.2 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-MYND PF01753.13 KII83069.1 - 1e-08 34.8 10.0 2e-08 33.9 6.9 1.5 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.13 KII83070.1 - 1.6e-22 79.6 0.1 2.8e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII83070.1 - 7.4e-05 22.5 11.4 0.00012 21.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.14 KII83070.1 - 1.3 8.6 5.2 2.8 7.6 3.6 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FB_lectin PF07367.6 KII83073.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal fruit body lectin Fungal_trans PF04082.13 KII83074.1 - 5.2e-20 71.4 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII83074.1 - 6.5e-06 25.9 12.4 1.1e-05 25.2 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.7 KII83075.1 - 7.4e-30 103.6 0.0 1.4e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII83075.1 - 1.2e-27 96.3 0.2 4.9e-26 91.0 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KII83075.1 - 4.5e-08 32.8 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KII83075.1 - 0.00032 20.8 0.2 0.0013 18.9 0.1 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KII83075.1 - 0.013 14.1 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3861 PF12977.2 KII83075.1 - 0.029 14.4 0.0 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) HTH_6 PF01418.12 KII83075.1 - 0.25 11.0 0.2 0.53 10.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family adh_short PF00106.20 KII83075.1 - 2.1 8.2 7.7 0.33 10.8 0.5 3.0 3 1 0 3 3 3 0 short chain dehydrogenase Filament PF00038.16 KII83077.1 - 0.1 12.0 15.9 0.18 11.2 1.7 2.7 2 1 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 KII83077.1 - 0.15 10.7 3.1 0.45 9.1 2.2 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 KII83077.1 - 0.23 10.6 9.2 0.5 9.5 2.2 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 KII83077.1 - 0.29 10.6 2.4 0.76 9.3 1.7 1.7 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Spc34 PF08657.5 KII83077.1 - 0.39 10.3 3.2 0.89 9.1 2.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Spc34 Phage_GP20 PF06810.6 KII83077.1 - 0.44 9.9 5.2 0.42 10.0 0.3 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 Frankia_peptide PF14407.1 KII83077.1 - 1.5 8.6 12.8 0.45 10.3 2.3 3.7 4 1 0 4 4 4 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Cep57_MT_bd PF06657.8 KII83077.1 - 3.2 7.7 8.9 0.77 9.7 2.2 2.9 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Cluap1 PF10234.4 KII83077.1 - 4.2 6.4 7.2 0.18 10.9 0.6 1.9 3 0 0 3 3 3 0 Clusterin-associated protein-1 Lebercilin PF15619.1 KII83077.1 - 4.3 6.7 15.0 0.18 11.2 4.7 2.5 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.5 KII83077.1 - 6 7.1 6.8 6.4 7.0 0.2 3.4 2 1 1 3 3 3 0 Tup N-terminal Mto2_bdg PF12808.2 KII83077.1 - 8.8 6.5 18.0 0.8 9.8 1.0 3.9 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Leu_zip PF15294.1 KII83078.1 - 0.034 13.2 7.4 0.033 13.3 4.0 1.5 1 1 0 1 1 1 0 Leucine zipper Macoilin PF09726.4 KII83078.1 - 0.17 10.1 3.2 0.21 9.8 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein MCC-bdg_PDZ PF10506.4 KII83078.1 - 0.73 9.7 9.1 3.2 7.6 0.6 3.0 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2570 PF10828.3 KII83078.1 - 0.91 9.1 7.8 4.8 6.8 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) WEMBL PF05701.6 KII83078.1 - 1.5 7.1 28.6 3.9 5.8 0.1 3.0 1 1 2 3 3 3 0 Weak chloroplast movement under blue light IncA PF04156.9 KII83078.1 - 1.9 8.0 15.8 6.2 6.3 7.6 2.9 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 KII83078.1 - 3.3 6.2 5.9 6.2 5.3 3.1 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.10 KII83078.1 - 5.6 6.5 10.4 2.6 7.6 0.2 3.8 3 1 2 5 5 5 0 Septum formation initiator zf-H2C2_5 PF13909.1 KII83081.1 - 0.013 15.6 1.0 0.013 15.6 0.7 2.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Tet_JBP PF12851.2 KII83082.1 - 4.1e-12 45.7 0.0 5.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily PSK_trans_fac PF07704.6 KII83083.1 - 1.6 9.4 4.6 16 6.2 0.6 2.6 2 1 0 2 2 2 0 Rv0623-like transcription factor GP46 PF07409.7 KII83084.1 - 0.025 13.8 0.1 0.025 13.8 0.0 2.2 3 0 0 3 3 3 0 Phage protein GP46 UBN2_3 PF14244.1 KII83084.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVP_2 PF08284.6 KII83085.1 - 1.3e-06 28.3 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KII83085.1 - 5.4e-05 23.6 0.0 8.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KII83085.1 - 0.017 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease MAD PF05557.8 KII83085.1 - 0.045 11.8 0.2 0.059 11.4 0.2 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Zn_clus PF00172.13 KII83088.1 - 2.9 7.8 10.7 3.3 7.7 2.6 2.0 1 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 KII83092.1 - 1.9e-10 40.2 0.0 2.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Myb_DNA-binding PF00249.26 KII83094.1 - 0.00037 20.4 0.4 0.27 11.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SR-25 PF10500.4 KII83100.1 - 0.0011 18.5 18.1 0.0022 17.5 12.6 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dsh_C PF12316.3 KII83100.1 - 0.023 14.7 5.8 0.035 14.2 4.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal YL1 PF05764.8 KII83100.1 - 0.19 11.3 27.1 0.029 13.9 16.0 1.6 2 0 0 2 2 2 0 YL1 nuclear protein DUF2201_N PF13203.1 KII83100.1 - 0.32 10.1 8.3 0.43 9.6 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 KII83100.1 - 1.5 8.6 13.7 2.3 8.0 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 KII83100.1 - 7.4 5.4 5.4 10 5.0 3.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.11 KII83100.1 - 9 5.6 15.5 2.4 7.4 8.5 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 Leo1 PF04004.8 KII83102.1 - 0.013 15.2 2.8 0.02 14.6 1.8 1.4 1 1 1 2 2 2 0 Leo1-like protein DUF1510 PF07423.6 KII83102.1 - 0.017 14.4 7.6 0.02 14.2 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 KII83102.1 - 0.025 13.1 0.8 0.025 13.1 0.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP1_TM PF14812.1 KII83102.1 - 0.037 14.3 5.9 0.058 13.7 4.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 KII83102.1 - 0.041 11.9 5.5 0.037 12.0 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 KII83102.1 - 0.079 12.6 4.8 0.1 12.2 3.3 1.2 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 KII83102.1 - 0.13 10.6 6.6 0.13 10.5 4.5 1.0 1 0 0 1 1 1 0 Hsp90 protein Nucleoplasmin PF03066.10 KII83102.1 - 0.15 11.5 10.0 0.22 11.0 6.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 KII83102.1 - 0.2 10.9 14.9 0.23 10.6 10.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Spore_coat_CotO PF14153.1 KII83102.1 - 0.27 10.6 8.1 0.28 10.6 5.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_3_Rpc31 PF11705.3 KII83102.1 - 0.44 10.4 12.2 0.51 10.2 8.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 KII83102.1 - 0.47 8.3 10.4 0.48 8.2 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family AIF_C PF14721.1 KII83102.1 - 0.47 10.6 2.1 0.6 10.3 1.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.7 KII83102.1 - 0.51 9.4 11.8 0.57 9.2 8.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleo_P87 PF07267.6 KII83102.1 - 0.62 8.6 7.1 0.68 8.5 4.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myc_N PF01056.13 KII83102.1 - 0.66 9.0 9.2 0.72 8.9 6.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Merozoite_SPAM PF07133.6 KII83102.1 - 0.67 9.8 17.6 0.92 9.3 12.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Zip PF02535.17 KII83102.1 - 0.79 8.6 4.6 0.81 8.6 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.9 KII83102.1 - 1.7 8.1 8.9 1.9 7.9 6.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3827 PF12877.2 KII83102.1 - 1.7 6.6 5.1 2 6.4 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TFIIF_alpha PF05793.7 KII83102.1 - 1.8 6.8 16.8 1.9 6.7 11.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.11 KII83102.1 - 1.9 7.3 6.7 2.3 7.1 4.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sec62 PF03839.11 KII83102.1 - 2.2 7.6 4.1 2.9 7.2 2.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.12 KII83102.1 - 2.3 6.9 3.8 2.5 6.8 2.6 1.0 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 KII83102.1 - 2.7 6.7 9.6 3 6.6 6.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Trypan_PARP PF05887.6 KII83102.1 - 3.2 7.5 14.8 3.9 7.2 10.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 KII83102.1 - 4.2 5.7 15.2 4.7 5.5 10.6 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpc4 PF05132.9 KII83102.1 - 4.2 7.3 7.2 5.9 6.8 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.12 KII83102.1 - 4.9 6.8 6.6 5.6 6.6 4.5 1.1 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 KII83102.1 - 6.7 5.8 11.6 8.6 5.4 8.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Adeno_terminal PF02459.10 KII83102.1 - 8.2 4.4 10.2 10 4.1 7.1 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Ycf1 PF05758.7 KII83102.1 - 9.2 3.8 7.0 11 3.6 4.8 1.0 1 0 0 1 1 1 0 Ycf1 VID27 PF08553.5 KII83102.1 - 9.3 4.3 9.7 11 4.1 6.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ribosomal_60s PF00428.14 KII83104.1 - 3.5 8.1 5.5 5.1 7.5 3.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAP_N PF01213.14 KII83104.1 - 9.6 5.3 6.1 11 5.2 4.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1792 PF08759.6 KII83105.1 - 0.042 13.4 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) DUF2197 PF09963.4 KII83105.1 - 0.087 12.7 0.6 0.19 11.7 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF4413 PF14372.1 KII83106.1 - 0.0001 22.2 0.1 0.00015 21.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 KII83107.1 - 6.1e-14 51.4 0.1 7.3e-14 51.1 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tudor-knot PF11717.3 KII83116.1 - 0.0066 16.1 1.4 0.018 14.7 1.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1510 PF07423.6 KII83116.1 - 0.37 10.1 0.0 0.37 10.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1510) Chromo PF00385.19 KII83116.1 - 0.48 10.1 6.0 0.98 9.1 4.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Dynamin_N PF00350.18 KII83118.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 Dynamin family TMF_DNA_bd PF12329.3 KII83120.1 - 0.021 14.6 1.9 0.044 13.5 1.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KII83120.1 - 0.027 13.4 4.7 0.019 13.9 2.3 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 KII83120.1 - 0.029 14.2 0.7 0.052 13.4 0.5 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 KII83120.1 - 0.039 13.7 1.2 0.05 13.4 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SSFA2_C PF14723.1 KII83120.1 - 0.046 13.4 0.1 0.078 12.7 0.1 1.4 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus IncA PF04156.9 KII83120.1 - 0.055 13.0 0.4 0.089 12.3 0.3 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KII83120.1 - 0.1 12.1 1.0 0.18 11.3 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2570 PF10828.3 KII83120.1 - 0.13 11.9 0.7 0.21 11.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) F-box PF00646.28 KII83121.1 - 2.7e-06 26.8 0.0 7.7e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain Amidase02_C PF12123.3 KII83122.1 - 0.0037 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-l-alanine amidase Nop52 PF05997.7 KII83122.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 DUF3402 PF11882.3 KII83128.1 - 0.047 12.7 0.1 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Dimer_Tnp_hAT PF05699.9 KII83130.1 - 8.7e-10 38.0 0.2 9.4e-10 37.9 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rsc14 PF08586.5 KII83132.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit JmjC PF02373.17 KII83135.1 - 7.8e-11 42.2 0.0 6.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KII83135.1 - 0.0028 17.2 0.0 0.0072 15.8 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KII83135.1 - 0.1 12.1 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Cupin domain CBFD_NFYB_HMF PF00808.18 KII83137.1 - 2.9e-08 33.6 0.4 5.8e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KII83137.1 - 0.00014 21.9 0.1 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KII83137.1 - 0.022 14.7 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KII83137.1 - 0.033 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIIF_alpha PF05793.7 KII83140.1 - 0.94 7.7 6.3 1.2 7.4 4.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zn_clus PF00172.13 KII83141.1 - 4.1e-05 23.4 8.9 9.5e-05 22.2 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_C PF00271.26 KII83142.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII83144.1 - 3.8e-07 29.7 0.0 4.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 KII83144.1 - 0.0014 17.2 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 KII83144.1 - 0.14 11.9 0.1 0.14 11.9 0.1 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit YL1 PF05764.8 KII83146.1 - 0.0028 17.2 19.6 0.0053 16.3 13.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein EBV-NA3 PF05009.7 KII83146.1 - 0.074 12.3 0.9 0.099 11.8 0.6 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RR_TM4-6 PF06459.7 KII83146.1 - 0.46 10.3 7.6 0.58 10.0 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVP PF00077.15 KII83147.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KII83147.1 - 0.052 14.0 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.5 KII83147.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 2 0 0 2 2 2 0 Aspartyl protease DUF2623 PF11115.3 KII83150.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Dimer_Tnp_hAT PF05699.9 KII83154.1 - 3.3e-06 26.6 0.2 4.1e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TUG-UBL1 PF11470.3 KII83154.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 GLUT4 regulating protein TUG GTF2I PF02946.9 KII83156.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 GTF2I-like repeat Tet_JBP PF12851.2 KII83157.1 - 6.8e-15 54.7 0.0 8.7e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CheZ PF04344.8 KII83158.1 - 0.054 13.1 3.1 0.062 12.9 0.9 2.0 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF883 PF05957.8 KII83158.1 - 0.24 11.8 5.2 4.4 7.7 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) UBN2_3 PF14244.1 KII83159.1 - 0.00074 19.1 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KII83159.1 - 0.026 13.9 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DEAD PF00270.24 KII83164.1 - 1.3e-15 57.2 0.0 1.6e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII83164.1 - 2e-08 34.2 0.0 2.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KII83164.1 - 0.087 12.9 0.1 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain GHMP_kinases_N PF00288.21 KII83165.1 - 7.8e-08 32.2 1.5 7.8e-08 32.2 1.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KII83165.1 - 0.00068 19.7 0.1 0.0027 17.8 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal Ferrochelatase PF00762.14 KII83166.1 - 7.5e-31 107.2 0.1 4.8e-13 48.7 0.0 3.8 2 2 2 4 4 4 4 Ferrochelatase VHS PF00790.14 KII83166.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 VHS domain Helicase_C PF00271.26 KII83167.1 - 1.3e-09 37.7 0.0 4.1e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII83167.1 - 6.8e-07 28.9 0.0 1.7e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KII83167.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KII83167.1 - 0.099 11.2 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Tet_JBP PF12851.2 KII83173.1 - 5.5e-11 42.0 0.0 6.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Kelch_4 PF13418.1 KII83176.1 - 1.9e-13 49.9 4.1 3.4e-07 29.9 0.1 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KII83176.1 - 2.6e-10 40.1 2.5 9.8e-05 22.4 0.6 3.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KII83176.1 - 9.1e-08 31.9 0.7 0.001 19.1 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 KII83176.1 - 3.2e-07 30.1 0.6 0.067 13.1 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KII83176.1 - 1.1e-06 28.1 2.3 0.00084 18.8 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 KII83176.1 - 8.1e-05 22.2 1.4 1.7 8.5 0.0 3.8 4 0 0 4 4 4 2 Kelch motif SDA1 PF05285.7 KII83184.1 - 0.00021 20.6 32.7 0.00027 20.3 22.7 1.1 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 KII83184.1 - 0.0003 19.4 28.2 0.0004 19.0 19.6 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 KII83184.1 - 0.0079 14.1 30.5 0.01 13.8 21.2 1.1 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 KII83184.1 - 0.046 12.9 25.3 0.061 12.5 17.3 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Acetyltransf_3 PF13302.1 KII83185.1 - 0.0022 18.1 0.1 0.0023 18.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SnoaL_2 PF12680.2 KII83185.1 - 0.014 15.7 0.2 0.018 15.4 0.2 1.2 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_3 PF13474.1 KII83185.1 - 0.08 12.9 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Acetyltransf_1 PF00583.19 KII83186.1 - 8.4e-08 32.1 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KII83186.1 - 6.9e-06 26.2 0.0 3.8e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII83186.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA_bind_2 PF13725.1 KII83187.1 - 0.032 14.3 0.6 0.072 13.2 0.5 1.7 1 1 1 2 2 2 0 Possible tRNA binding domain ESR1_C PF12743.2 KII83187.1 - 1.4 8.5 5.9 0.81 9.2 2.4 1.8 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Phage_lambd_GpG PF06894.6 KII83188.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) Cytomega_gL PF01801.11 KII83189.1 - 0.12 11.9 0.0 8.9 5.7 0.0 2.0 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein L Acetyltransf_3 PF13302.1 KII83190.1 - 0.0016 18.6 0.1 0.0084 16.2 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Nucleoplasmin PF03066.10 KII83191.1 - 0.42 10.1 11.7 0.14 11.6 1.4 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF3245 PF11595.3 KII83191.1 - 3.6 7.8 11.5 2.4 8.4 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) RRM_1 PF00076.17 KII83192.1 - 3e-15 55.5 0.2 3.5e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII83192.1 - 2.4e-07 30.6 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII83192.1 - 6.8e-06 25.8 0.0 0.00099 18.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KII83193.1 - 2.2e-22 78.4 0.7 3.5e-22 77.8 0.1 1.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Effector_1 PF04518.7 KII83195.1 - 0.04 12.9 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Metal_resist PF13801.1 KII83195.1 - 0.81 9.6 6.0 3.5 7.6 4.0 2.0 1 1 0 1 1 1 0 Heavy-metal resistance Asp_protease_2 PF13650.1 KII83196.1 - 0.0084 16.5 0.0 0.024 15.1 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KII83196.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KII83196.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 KII83197.1 - 1.2e-05 25.0 1.9 4.1e-05 23.2 1.3 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KII83197.1 - 0.022 14.4 0.3 0.06 13.0 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KII83197.1 - 0.031 13.7 2.7 0.081 12.4 1.8 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1631 PF07793.6 KII83197.1 - 0.16 10.0 1.5 0.93 7.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) UBN2_3 PF14244.1 KII83198.1 - 0.034 13.6 0.0 3.6 7.1 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KII83199.1 - 1.9e-07 30.5 0.1 2.9e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Peptidase_C48 PF02902.14 KII83205.1 - 5.6e-09 35.9 0.3 5.7e-09 35.9 0.2 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.13 KII83207.1 - 8.6e-05 22.3 8.9 8.6e-05 22.3 6.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecl1 PF12855.2 KII83208.1 - 2e-05 23.7 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Life-span regulatory factor zf-MYND PF01753.13 KII83211.1 - 1.3e-10 40.9 9.0 4e-10 39.4 6.4 1.7 1 1 1 2 2 2 1 MYND finger adh_short PF00106.20 KII83213.1 - 2e-10 40.8 0.1 2.1e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII83213.1 - 7.9e-06 25.6 0.1 8.9e-06 25.4 0.1 1.0 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KII83213.1 - 0.085 11.8 0.1 0.087 11.7 0.1 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase TraE PF05309.6 KII83214.1 - 0.087 11.9 0.8 0.16 11.1 0.3 1.6 1 1 1 2 2 2 0 TraE protein Fer4_7 PF12838.2 KII83219.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 KII83219.1 - 0.079 12.8 0.7 0.2 11.5 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain zf-B_box PF00643.19 KII83222.1 - 2.1 8.2 8.3 5.1 7.0 5.7 1.7 1 0 0 1 1 1 0 B-box zinc finger Toxin_7 PF05980.7 KII83224.1 - 0.0067 16.4 3.7 0.016 15.2 2.6 1.6 1 0 0 1 1 1 1 Toxin 7 UPF0506 PF11703.3 KII83224.1 - 0.079 12.9 3.8 0.15 12.0 2.6 1.5 1 0 0 1 1 1 0 UPF0506 Toxin_12 PF07740.7 KII83224.1 - 0.18 12.2 3.6 0.37 11.3 2.5 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin Aldedh PF00171.17 KII83226.1 - 6e-86 288.5 0.0 7.4e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII83226.1 - 0.019 13.7 0.1 0.045 12.4 0.1 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) ICMT PF04140.9 KII83227.1 - 5e-14 52.2 0.9 7.7e-14 51.6 0.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII83227.1 - 5.5e-13 48.9 4.3 1.4e-12 47.6 0.9 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KII83227.1 - 0.018 13.6 0.2 0.028 12.9 0.1 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF3040 PF11239.3 KII83227.1 - 0.62 10.1 4.4 9.1 6.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DAHP_synth_2 PF01474.11 KII83228.1 - 2.8e-178 592.7 0.0 3.3e-178 592.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HECT PF00632.20 KII83229.1 - 8.3e-95 317.5 0.0 1.2e-94 316.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KII83229.1 - 0.074 12.7 0.1 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Mito_carr PF00153.22 KII83230.1 - 5.3e-27 93.3 3.0 2.2e-14 52.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.16 KII83231.1 - 4.6e-28 97.6 0.2 6e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RIP PF00161.14 KII83231.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 Ribosome inactivating protein MFS_1 PF07690.11 KII83239.1 - 9.1e-22 77.2 37.2 4.2e-21 75.0 25.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 KII83240.1 - 4.3e-121 405.0 0.0 5.4e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 G-patch_2 PF12656.2 KII83241.1 - 3.9e-26 90.7 0.8 1.5e-25 88.8 0.0 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 KII83241.1 - 0.074 12.8 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 G-patch domain Fe-S_biosyn PF01521.15 KII83242.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Acetyltransf_1 PF00583.19 KII83243.1 - 1.7e-05 24.7 0.0 6.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII83243.1 - 0.017 15.3 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KII83243.1 - 0.024 14.2 0.0 0.035 13.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII83243.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 KII83244.1 - 2.8e-113 379.2 0.0 3.4e-113 378.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KII83244.1 - 0.00024 21.0 0.1 0.0031 17.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BUD22 PF09073.5 KII83249.1 - 0.017 14.2 11.5 0.018 14.1 8.0 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KII83249.1 - 1.1 7.1 11.6 1.1 7.0 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KII83249.1 - 1.4 8.1 6.7 1.6 8.0 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIE-A_C-term PF11521.3 KII83249.1 - 1.8 8.5 9.2 2.9 7.9 6.4 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Ebola_NP PF05505.7 KII83249.1 - 2.1 6.2 6.9 2.3 6.1 4.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3682 PF12446.3 KII83249.1 - 2.3 8.5 12.1 3.7 7.8 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) MRI PF15325.1 KII83249.1 - 2.5 9.1 7.2 3 8.8 5.0 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection PPP4R2 PF09184.6 KII83249.1 - 5.9 6.3 11.4 6.9 6.1 7.9 1.1 1 0 0 1 1 1 0 PPP4R2 HTH_29 PF13551.1 KII83250.1 - 3.9e-06 26.9 0.0 4.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KII83250.1 - 0.0076 17.0 0.1 0.011 16.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 KII83250.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 KII83250.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MAGP PF05507.6 KII83251.1 - 0.48 10.2 2.9 0.57 9.9 2.0 1.1 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Phospholamban PF04272.9 KII83252.1 - 0.25 10.7 0.0 0.56 9.6 0.0 1.5 1 0 0 1 1 1 0 Phospholamban Cauli_VI PF01693.11 KII83253.1 - 6e-20 70.9 0.3 7e-09 35.5 0.0 3.2 3 0 0 3 3 3 3 Caulimovirus viroplasmin HA PF03457.9 KII83254.1 - 9.8 6.3 7.1 2.6 8.2 0.0 2.8 2 1 0 2 2 2 0 Helicase associated domain ArfGap PF01412.13 KII83256.1 - 0.17 11.7 4.1 1.2 8.9 3.5 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zf-B_box PF00643.19 KII83256.1 - 0.64 9.9 7.3 1.8 8.5 5.1 1.7 1 0 0 1 1 1 0 B-box zinc finger TPR_10 PF13374.1 KII83258.1 - 2.9e-54 179.5 0.4 1.5e-05 24.7 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KII83258.1 - 1.1e-46 156.6 8.4 3.1e-11 43.0 0.0 6.3 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KII83258.1 - 2.8e-23 79.8 7.6 0.029 14.1 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 KII83258.1 - 4.7e-17 60.7 19.5 0.14 11.7 0.1 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KII83258.1 - 3.3e-16 58.6 8.9 0.00082 18.9 0.1 6.5 5 3 0 5 5 5 4 TPR repeat TPR_2 PF07719.12 KII83258.1 - 3.7e-14 51.4 16.1 0.85 9.6 0.0 8.3 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_4 PF07721.9 KII83258.1 - 1.3e-13 49.9 0.0 1.2 9.7 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KII83258.1 - 2.6e-13 49.8 8.5 0.013 15.5 0.0 5.0 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KII83258.1 - 3.5e-13 48.6 6.8 1.1 9.6 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII83258.1 - 4.7e-13 49.4 6.2 0.0025 18.4 0.1 6.8 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KII83258.1 - 1.5e-12 46.9 8.2 0.28 11.9 0.0 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII83258.1 - 2.4e-10 40.5 12.0 0.11 12.8 0.1 6.7 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KII83258.1 - 1.2e-07 30.9 17.0 0.22 11.3 0.3 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_3 PF07720.7 KII83258.1 - 4.4e-07 29.5 10.3 0.28 11.0 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KII83258.1 - 2.3e-06 27.6 9.1 2.1 8.5 0.1 5.5 3 2 3 6 6 6 3 Tetratricopeptide repeat HSA PF07529.8 KII83258.1 - 0.0002 21.0 1.5 8.1 6.3 0.1 4.8 5 0 0 5 5 5 0 HSA DUF2664 PF10867.3 KII83258.1 - 0.00037 21.0 0.7 23 5.6 0.0 4.7 5 1 0 5 5 4 0 Protein of unknown function (DUF2664) PPR PF01535.15 KII83258.1 - 0.00044 20.0 9.6 15 5.8 0.1 7.6 9 0 0 9 9 8 0 PPR repeat TPR_6 PF13174.1 KII83258.1 - 0.0014 18.9 10.7 18 6.0 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat PFO_beta_C PF12367.3 KII83258.1 - 0.012 15.4 0.0 8.4 6.4 0.0 3.0 1 1 2 3 3 3 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Tcf25 PF04910.9 KII83258.1 - 0.033 13.1 1.6 5.1 5.9 0.0 3.3 3 1 1 4 4 4 0 Transcriptional repressor TCF25 DUF486 PF04342.7 KII83258.1 - 0.045 13.8 0.3 0.2 11.7 0.0 2.3 3 1 1 4 4 2 0 Protein of unknown function, DUF486 SecD-TM1 PF13721.1 KII83258.1 - 0.045 14.0 0.0 19 5.5 0.0 3.1 1 1 2 3 3 3 0 SecD export protein N-terminal TM region HHH_3 PF12836.2 KII83258.1 - 0.2 11.6 3.1 17 5.4 0.0 4.1 4 0 0 4 4 4 0 Helix-hairpin-helix motif DUF4477 PF14780.1 KII83258.1 - 0.33 10.3 7.5 1.6 8.0 0.1 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4477) Patatin PF01734.17 KII83259.1 - 4.9e-20 72.3 0.0 7.5e-19 68.4 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Oxidored_FMN PF00724.15 KII83260.1 - 6.4e-105 350.8 0.0 7.3e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII83261.1 - 2.4e-16 59.6 0.0 2.7e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII83262.1 - 2.6e-48 164.7 0.0 2.9e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII83263.1 - 3e-98 328.9 0.0 3.4e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.2 KII83264.1 - 1.5e-09 37.4 1.7 3.4e-09 36.2 1.2 1.7 1 0 0 1 1 1 1 F-box-like TMF_TATA_bd PF12325.3 KII83264.1 - 0.0088 15.7 0.1 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding F-box PF00646.28 KII83264.1 - 0.076 12.6 3.7 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 F-box domain Cast PF10174.4 KII83264.1 - 0.14 10.2 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Oxidored_FMN PF00724.15 KII83265.1 - 6.1e-103 344.3 0.0 7.7e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII83266.1 - 2.2e-101 339.3 0.0 2.5e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII83267.1 - 8.4e-100 334.0 0.0 9.5e-100 333.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 KII83267.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Tautomerase enzyme CBM_X2 PF03442.9 KII83269.1 - 0.27 11.1 2.1 0.29 11.0 0.3 1.9 2 1 0 2 2 2 0 Carbohydrate binding domain X2 NTP_transferase PF00483.18 KII83271.1 - 1.4e-42 145.7 0.0 2.5e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KII83271.1 - 1.1e-07 32.0 0.1 2.5e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 KII83271.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CCDC92 PF14916.1 KII83271.1 - 0.054 13.0 0.4 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ADH_zinc_N PF00107.21 KII83272.1 - 4.1e-18 65.1 0.0 6.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII83272.1 - 4.5e-14 53.4 0.0 9.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dscam_C PF12355.3 KII83273.1 - 0.024 14.8 1.6 0.031 14.5 0.8 1.5 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DUF281 PF03436.8 KII83275.1 - 0.95 9.5 7.4 2.3 8.3 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF281) Apolipoprotein PF01442.13 KII83278.1 - 2.9e-05 23.6 3.1 4.3e-05 23.1 2.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3584 PF12128.3 KII83278.1 - 9 3.4 15.9 12 3.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ribosomal_S14 PF00253.16 KII83279.1 - 0.46 9.9 2.8 0.85 9.0 2.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e CHASE3 PF05227.8 KII83282.1 - 0.033 13.8 0.4 0.05 13.2 0.2 1.3 1 0 0 1 1 1 0 CHASE3 domain DUF2644 PF10841.3 KII83283.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) F-box PF00646.28 KII83284.1 - 0.00044 19.8 0.2 0.0015 18.1 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII83284.1 - 0.0066 16.1 0.1 0.033 13.9 0.1 2.3 1 0 0 1 1 1 1 F-box-like CpXC PF14353.1 KII83284.1 - 0.04 13.8 0.6 0.04 13.8 0.4 2.7 3 0 0 3 3 3 0 CpXC protein Beta-lactamase PF00144.19 KII83285.1 - 9.5e-42 143.1 1.1 6.1e-41 140.5 0.8 1.8 1 1 0 1 1 1 1 Beta-lactamase tRNA_int_end_N2 PF12928.2 KII83286.1 - 1e-21 76.1 0.0 1.6e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KII83286.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain HMG_box PF00505.14 KII83287.1 - 1.2e-13 51.0 0.9 1.7e-13 50.6 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII83287.1 - 7.2e-08 32.6 0.2 8e-08 32.5 0.2 1.1 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KII83287.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 GIT_SHD PF08518.6 KII83288.1 - 0.00055 19.2 0.2 0.00089 18.5 0.1 1.3 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT FAD_binding_2 PF00890.19 KII83289.1 - 1.3e-85 287.7 2.4 1.5e-85 287.5 1.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII83289.1 - 5.3e-14 51.8 2.4 7.6e-13 48.0 1.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII83289.1 - 8.6e-11 42.0 1.5 1e-08 35.3 1.1 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII83289.1 - 7.4e-10 38.7 3.1 1.6e-09 37.6 0.2 3.0 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KII83289.1 - 2.4e-08 33.4 0.6 4.9e-08 32.4 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII83289.1 - 3.7e-07 29.5 0.1 6.1e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KII83289.1 - 4.1e-06 27.0 0.5 1.2e-05 25.4 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII83289.1 - 7e-06 24.7 5.0 0.00017 20.1 0.3 3.0 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 KII83289.1 - 1.5e-05 24.1 2.3 0.0074 15.4 0.5 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KII83289.1 - 5.9e-05 22.0 4.3 0.00068 18.6 0.5 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 KII83289.1 - 0.0008 18.5 0.7 0.0021 17.1 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KII83289.1 - 0.0013 18.5 0.6 0.43 10.3 0.2 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KII83289.1 - 0.0026 18.1 0.6 0.038 14.3 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII83289.1 - 0.01 14.7 0.2 0.018 13.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KII83289.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KII83289.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nnf1 PF03980.9 KII83293.1 - 0.0049 16.8 0.8 0.0095 15.9 0.5 1.4 1 0 0 1 1 1 1 Nnf1 FAD_binding_2 PF00890.19 KII83294.1 - 3e-87 293.1 1.1 3.9e-87 292.8 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KII83294.1 - 8.5e-23 79.9 0.0 2e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KII83294.1 - 1.6e-13 50.3 2.6 2.8e-12 46.2 1.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII83294.1 - 1.9e-12 47.5 0.0 5.9e-10 39.3 0.0 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII83294.1 - 1.3e-10 41.1 0.8 9e-10 38.4 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KII83294.1 - 1.6e-09 37.3 0.3 3e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII83294.1 - 2.4e-07 30.1 0.1 4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KII83294.1 - 1.8e-06 27.1 2.6 6.9e-05 21.8 0.5 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KII83294.1 - 2.2e-06 27.8 0.8 7.8e-06 26.0 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII83294.1 - 3.7e-06 25.6 4.9 7.2e-05 21.4 0.4 3.0 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 KII83294.1 - 1.3e-05 24.3 1.1 0.0025 16.9 0.2 2.5 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.19 KII83294.1 - 0.0005 19.2 1.2 0.00093 18.3 0.4 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KII83294.1 - 0.00081 19.1 0.5 0.037 13.8 0.3 2.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KII83294.1 - 0.0036 17.6 0.6 0.04 14.3 0.2 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KII83294.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KII83294.1 - 0.016 14.1 0.4 0.028 13.3 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KII83294.1 - 0.019 14.5 0.2 0.13 11.8 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KII83294.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M19 PF01244.16 KII83295.1 - 1.2e-104 349.7 0.0 1.5e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Nnf1 PF03980.9 KII83296.1 - 0.025 14.5 0.2 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Nnf1 DUF2520 PF10728.4 KII83296.1 - 0.04 13.3 0.1 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DUF883 PF05957.8 KII83296.1 - 1 9.7 5.7 8.8 6.8 1.3 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF883 PF05957.8 KII83298.1 - 3.4 8.1 5.6 6.9 7.1 1.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2421 PF10334.4 KII83301.1 - 5.4e-17 62.1 0.1 6.1e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Beta-lactamase PF00144.19 KII83304.1 - 1.3e-45 155.8 0.2 2.4e-45 154.9 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase AAA_17 PF13207.1 KII83305.1 - 1.7e-06 28.8 0.0 7.6e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII83305.1 - 7.8e-06 26.2 0.1 0.00012 22.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII83305.1 - 0.0019 18.0 0.1 0.0066 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII83305.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KII83305.1 - 0.034 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KII83305.1 - 0.055 12.3 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DDE_1 PF03184.14 KII83307.1 - 1.6e-09 37.1 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FF PF01846.14 KII83310.1 - 0.11 12.4 0.2 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 FF domain zf-SNAP50_C PF12251.3 KII83311.1 - 0.0022 17.3 0.1 0.14 11.4 0.0 2.1 2 0 0 2 2 2 2 snRNA-activating protein of 50kDa MW C terminal F-box-like PF12937.2 KII83315.1 - 0.0072 16.0 1.9 0.015 15.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like SoxD PF04267.7 KII83315.1 - 0.068 12.9 0.6 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family F-box-like PF12937.2 KII83316.1 - 2e-05 24.2 0.3 4.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII83316.1 - 0.0003 20.3 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF4449 PF14613.1 KII83317.1 - 6.7e-29 100.9 0.3 1.2e-28 100.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) Ank_2 PF12796.2 KII83319.1 - 7.9e-22 77.4 0.1 8.7e-11 42.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII83319.1 - 5e-20 70.2 4.2 1.6e-07 30.7 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KII83319.1 - 5.2e-16 58.6 0.1 2.7e-08 34.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII83319.1 - 1.2e-15 56.0 0.4 0.00012 21.9 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KII83319.1 - 7.5e-12 45.0 0.9 2.8e-05 24.2 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Sod_Fe_C PF02777.13 KII83320.1 - 1.8e-34 117.7 0.0 3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KII83320.1 - 6.7e-33 112.7 3.3 1.4e-32 111.7 1.8 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 KII83320.1 - 0.14 12.0 3.3 0.39 10.6 1.5 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain GRP PF07172.6 KII83321.1 - 0.08 13.4 21.9 0.13 12.7 3.5 2.9 3 0 0 3 3 3 0 Glycine rich protein family IFT57 PF10498.4 KII83321.1 - 0.15 10.8 3.3 0.21 10.3 2.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 KII83321.1 - 6.9 6.2 12.7 12 5.4 8.8 1.3 1 0 0 1 1 1 0 IncA protein DUF3602 PF12223.3 KII83323.1 - 2.5e-12 46.9 24.4 7e-05 23.1 0.4 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) GATA PF00320.22 KII83324.1 - 0.2 11.0 3.0 1.9 7.9 0.2 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-MYND PF01753.13 KII83325.1 - 3.2e-09 36.5 9.7 6.6e-09 35.4 6.7 1.6 1 0 0 1 1 1 1 MYND finger zf-CCHC_5 PF14787.1 KII83327.1 - 0.0055 16.1 1.7 0.011 15.1 1.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 KII83327.1 - 0.026 14.4 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G SH3_9 PF14604.1 KII83328.1 - 4.6e-05 22.9 0.0 9.4e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII83328.1 - 0.0014 17.9 0.0 0.0032 16.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII83328.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Neisseria_TspB PF05616.8 KII83328.1 - 4.3 5.6 13.7 6.6 4.9 9.5 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Tweety PF04906.8 KII83331.1 - 0.042 12.2 1.0 0.07 11.5 0.7 1.3 1 0 0 1 1 1 0 Tweety DUF2568 PF10823.3 KII83331.1 - 0.13 12.4 5.7 1.2 9.3 0.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2568) F-box PF00646.28 KII83333.1 - 0.00071 19.1 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII83333.1 - 0.063 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like Tweety PF04906.8 KII83334.1 - 0.046 12.1 0.7 0.065 11.6 0.5 1.1 1 0 0 1 1 1 0 Tweety PepSY_TM PF03929.11 KII83336.1 - 0.32 11.4 4.3 0.88 10.0 0.6 3.1 2 0 0 2 2 2 0 PepSY-associated TM helix Acetyltransf_1 PF00583.19 KII83338.1 - 5.4e-12 45.5 0.3 1.1e-11 44.6 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII83338.1 - 3.9e-10 39.7 0.0 2.2e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII83338.1 - 6.4e-08 32.7 0.0 8.6e-06 25.8 0.0 2.2 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII83338.1 - 0.0018 18.0 0.0 0.0063 16.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AAA_13 PF13166.1 KII83341.1 - 0.00013 20.6 9.7 0.00013 20.6 6.7 2.1 2 0 0 2 2 2 2 AAA domain Tropomyosin_1 PF12718.2 KII83341.1 - 0.016 15.0 6.1 0.016 15.0 4.2 4.0 2 2 1 3 3 3 0 Tropomyosin like MscS_porin PF12795.2 KII83341.1 - 0.62 9.3 51.1 0.014 14.7 10.1 3.5 2 2 0 3 3 3 0 Mechanosensitive ion channel porin domain zf-C4pol PF14260.1 KII83341.1 - 1.8 8.6 5.8 1.5 8.9 0.3 3.4 2 2 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta IncA PF04156.9 KII83341.1 - 1.9 8.0 51.4 2.1 7.9 5.0 4.0 1 1 2 3 3 3 0 IncA protein FliJ PF02050.11 KII83341.1 - 2.9 7.9 41.8 0.33 10.9 3.0 4.0 1 1 3 4 4 4 0 Flagellar FliJ protein Acetyltransf_1 PF00583.19 KII83343.1 - 1.4e-11 44.2 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII83343.1 - 5.6e-09 36.0 0.0 7.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII83343.1 - 4.4e-07 30.0 0.0 5.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII83343.1 - 5.7e-06 26.2 0.0 8.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII83343.1 - 1.1e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein MU117 PF15474.1 KII83344.1 - 2.4e-11 43.9 9.7 2.9e-11 43.7 6.7 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family TPR_MLP1_2 PF07926.7 KII83345.1 - 3.7e-06 26.7 24.7 0.016 14.9 0.5 3.3 3 0 0 3 3 3 3 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KII83345.1 - 0.00015 19.6 44.0 0.052 11.2 5.5 3.2 2 1 1 3 3 3 3 Myosin tail DUF1875 PF08961.5 KII83345.1 - 0.00016 21.0 1.4 0.00016 21.0 0.9 2.9 3 2 1 4 4 4 1 Domain of unknown function (DUF1875) IncA PF04156.9 KII83345.1 - 0.00063 19.4 38.5 0.023 14.2 9.6 3.1 2 1 1 3 3 3 3 IncA protein DUF1664 PF07889.7 KII83345.1 - 0.0013 18.4 18.7 0.13 12.0 0.9 4.0 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) MscS_porin PF12795.2 KII83345.1 - 0.0017 17.7 38.2 0.044 13.1 10.0 3.5 2 2 1 3 3 3 2 Mechanosensitive ion channel porin domain ATG16 PF08614.6 KII83345.1 - 0.0078 16.0 13.9 0.0078 16.0 9.7 3.8 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KII83345.1 - 0.0086 14.6 22.5 0.0079 14.7 9.5 2.3 2 1 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 KII83345.1 - 0.011 14.8 12.8 0.56 9.3 0.4 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AlgF PF11182.3 KII83345.1 - 0.019 14.6 0.7 0.039 13.6 0.4 1.5 1 1 0 1 1 1 0 Alginate O-acetyl transferase AlgF Sec8_exocyst PF04048.9 KII83345.1 - 0.13 11.8 18.6 0.28 10.8 0.3 4.5 2 2 0 4 4 4 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 KII83345.1 - 0.22 10.1 32.2 0.98 8.0 4.4 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein CCDC144C PF14915.1 KII83345.1 - 0.23 10.3 29.0 0.26 10.1 0.2 3.3 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region Sigma54_activ_2 PF14532.1 KII83345.1 - 0.25 11.3 2.8 0.28 11.2 0.6 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4167 PF13763.1 KII83345.1 - 0.29 11.1 6.6 0.066 13.2 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Filament PF00038.16 KII83345.1 - 0.47 9.8 35.0 0.75 9.2 5.8 3.3 2 1 1 3 3 3 0 Intermediate filament protein Laminin_II PF06009.7 KII83345.1 - 0.58 9.9 26.4 0.33 10.7 1.5 3.8 2 1 2 4 4 4 0 Laminin Domain II DUF4201 PF13870.1 KII83345.1 - 0.87 9.0 26.7 0.045 13.1 1.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF3829 PF12889.2 KII83345.1 - 0.99 8.5 12.6 0.18 10.9 5.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) GAS PF13851.1 KII83345.1 - 1.1 8.3 30.2 0.53 9.4 4.1 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 KII83345.1 - 1.2 8.2 43.3 1.4 7.9 12.7 4.1 2 1 1 3 3 3 0 Tropomyosin DUF16 PF01519.11 KII83345.1 - 1.4 9.1 16.5 2.2 8.5 1.3 3.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4559 PF15112.1 KII83345.1 - 1.5 7.8 20.4 0.52 9.4 1.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4559) MAD PF05557.8 KII83345.1 - 1.5 6.7 36.3 0.067 11.2 4.2 2.4 2 1 0 2 2 2 0 Mitotic checkpoint protein AAA_27 PF13514.1 KII83345.1 - 2.4 5.7 35.6 0.4 8.3 16.7 2.4 2 1 0 2 2 2 0 AAA domain STAG PF08514.6 KII83345.1 - 2.4 7.8 8.5 0.13 11.9 0.7 2.8 2 1 1 3 3 3 0 STAG domain FliD_C PF07195.7 KII83345.1 - 3 7.0 13.7 1.4 8.1 0.2 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus HrpB7 PF09486.5 KII83345.1 - 5.6 6.8 33.8 1.8 8.4 3.7 4.3 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) CCDC155 PF14662.1 KII83345.1 - 5.9 6.4 39.6 0.024 14.2 5.5 3.8 2 2 0 3 3 3 0 Coiled-coil region of CCDC155 APG6 PF04111.7 KII83345.1 - 6.8 5.6 35.9 1 8.3 5.0 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 FUSC PF04632.7 KII83345.1 - 9 4.5 19.5 3.2 6.0 8.3 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family KIAA1430 PF13879.1 KII83345.1 - 9.8 6.6 13.3 0.11 12.9 1.7 3.2 2 2 0 2 2 1 0 KIAA1430 homologue zf-C2H2 PF00096.21 KII83346.1 - 3.7e-07 30.1 7.0 0.006 16.8 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII83346.1 - 1.2e-06 28.3 7.2 0.0067 16.6 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII83346.1 - 0.09 13.1 2.3 2.1 8.8 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Cep57_CLD_2 PF14197.1 KII83347.1 - 0.26 11.2 14.2 0.047 13.6 5.8 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF904 PF06005.7 KII83347.1 - 0.27 11.5 6.9 0.48 10.7 2.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 KII83347.1 - 0.33 10.7 3.2 2.7 7.7 0.5 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KII83347.1 - 0.36 11.1 2.3 5.3 7.4 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Filament PF00038.16 KII83347.1 - 0.9 8.9 14.3 1 8.7 6.9 2.5 2 1 0 2 2 2 0 Intermediate filament protein EspB PF05802.6 KII83349.1 - 3.5 6.5 12.7 0.076 11.9 4.2 1.6 2 0 0 2 2 2 0 Enterobacterial EspB protein SMC_N PF02463.14 KII83350.1 - 8.5e-27 93.8 0.0 2e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KII83350.1 - 2.3e-14 54.2 11.8 2.3e-14 54.2 8.2 4.2 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.1 KII83350.1 - 3.6e-05 22.9 0.0 3.6e-05 22.9 0.0 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 KII83350.1 - 0.00014 21.8 0.0 0.0039 17.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII83350.1 - 0.00036 20.0 0.0 0.00074 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF812 PF05667.6 KII83350.1 - 0.00075 18.1 23.7 0.00075 18.1 16.4 2.9 2 1 1 3 3 2 1 Protein of unknown function (DUF812) SbcCD_C PF13558.1 KII83350.1 - 0.0094 15.8 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KII83350.1 - 0.059 11.8 58.7 0.074 11.5 8.5 4.6 3 2 2 5 5 5 0 AAA domain MMR_HSR1 PF01926.18 KII83350.1 - 0.15 12.0 0.6 1 9.3 0.4 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase CALCOCO1 PF07888.6 KII83350.1 - 0.41 8.8 60.5 0.0045 15.3 18.9 3.3 2 1 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like ABC_tran PF00005.22 KII83350.1 - 0.5 10.6 15.4 0.15 12.3 0.2 4.5 3 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 KII83350.1 - 0.59 9.2 19.0 3.4 6.7 0.2 5.1 2 2 2 5 5 5 0 Reovirus sigma C capsid protein Bcr-Abl_Oligo PF09036.5 KII83350.1 - 3.1 7.8 9.1 0.49 10.3 0.9 3.4 3 0 0 3 3 2 0 Bcr-Abl oncoprotein oligomerisation domain Sec34 PF04136.10 KII83350.1 - 5.5 6.6 12.2 0.13 11.9 2.2 2.6 2 0 0 2 2 2 0 Sec34-like family APG6 PF04111.7 KII83352.1 - 8.7 5.2 21.9 0.13 11.2 5.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 APG6 PF04111.7 KII83353.1 - 1.5 7.8 4.6 2.6 6.9 3.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 KII83353.1 - 6.1 6.7 9.3 0.17 11.7 2.2 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Multi-haem_cyto PF13447.1 KII83355.1 - 0.003 16.6 0.9 0.0032 16.5 0.6 1.1 1 0 0 1 1 1 1 Seven times multi-haem cytochrome CxxCH ERM PF00769.14 KII83356.1 - 0.0019 17.8 13.4 0.0019 17.8 9.3 1.8 2 0 0 2 2 2 1 Ezrin/radixin/moesin family GAS PF13851.1 KII83356.1 - 0.073 12.2 4.2 0.16 11.1 2.9 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GAGA_bind PF06217.7 KII83356.1 - 2.3 8.1 6.8 0.25 11.2 0.6 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family APG6 PF04111.7 KII83356.1 - 4.4 6.2 13.2 0.071 12.1 4.0 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 IU_nuc_hydro PF01156.14 KII83357.1 - 1.1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.14 KII83358.1 - 3.7e-24 85.5 0.1 5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Lebercilin PF15619.1 KII83359.1 - 0.0093 15.4 5.5 0.0093 15.4 3.8 2.0 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.13 KII83359.1 - 0.01 15.5 11.1 0.93 9.2 0.3 3.7 2 1 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 KII83359.1 - 0.21 11.5 20.0 0.44 10.5 1.4 4.2 2 1 2 4 4 4 0 bZIP transcription factor FUSC PF04632.7 KII83359.1 - 0.32 9.3 6.5 0.46 8.8 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 KII83359.1 - 2.5 8.4 18.8 5 7.5 2.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KII83359.1 - 3.8 7.0 25.4 1.4 8.4 12.4 2.0 1 1 0 2 2 2 0 IncA protein IMPDH PF00478.20 KII83361.1 - 5.2e-132 440.0 3.6 7.7e-132 439.4 2.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KII83361.1 - 2.7e-16 59.0 0.1 9.8e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KII83361.1 - 1.1e-09 37.9 4.1 8.1e-07 28.4 1.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KII83361.1 - 1.4e-09 37.3 0.4 3.5e-09 35.9 0.3 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KII83361.1 - 4e-05 23.0 3.7 0.001 18.3 2.5 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 KII83361.1 - 0.0022 17.1 0.7 0.0045 16.0 0.5 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Homeobox PF00046.24 KII83362.1 - 6.6e-17 60.8 0.6 1e-16 60.3 0.4 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KII83362.1 - 1.8e-06 27.5 0.5 4e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain rve_2 PF13333.1 KII83362.1 - 0.12 12.4 0.7 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain LGT PF01790.13 KII83366.1 - 0.087 11.7 0.0 0.094 11.6 0.0 1.0 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Glyco_hydro_85 PF03644.8 KII83369.1 - 3.9e-74 249.5 0.0 5.8e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 RRM_1 PF00076.17 KII83371.1 - 1.2e-33 114.5 0.6 8e-17 60.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII83371.1 - 2.1e-27 94.8 0.5 2.8e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII83371.1 - 6.9e-12 45.0 0.5 2.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII83371.1 - 0.008 16.0 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif DUF4651 PF15513.1 KII83371.1 - 0.052 13.0 0.0 9.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Nop14 PF04147.7 KII83373.1 - 0.0016 16.4 3.1 0.0019 16.1 2.2 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 KII83373.1 - 0.033 13.4 3.3 0.056 12.7 2.3 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KII83373.1 - 0.097 10.6 3.2 0.13 10.2 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 KII83373.1 - 0.16 11.3 16.6 0.26 10.6 11.5 1.3 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 KII83373.1 - 0.54 9.2 11.8 1 8.3 8.2 1.4 1 0 0 1 1 1 0 BUD22 HOASN PF14515.1 KII83373.1 - 0.59 10.5 7.4 0.21 11.9 1.3 2.2 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices Peptidase_S10 PF00450.17 KII83375.1 - 1.9e-81 274.4 0.0 2.5e-81 273.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase His_binding PF02098.11 KII83375.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Tick histamine binding protein SNO PF01174.14 KII83376.1 - 7.9e-50 169.1 0.0 1.7e-48 164.7 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KII83376.1 - 5.3e-06 26.1 0.1 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 KII83376.1 - 0.01 15.1 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Putative amidotransferase DJ-1_PfpI PF01965.19 KII83376.1 - 0.024 14.1 0.1 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.12 KII83376.1 - 0.046 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 DUF4154 PF13689.1 KII83376.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Suf PF05843.9 KII83377.1 - 7.3e-72 242.4 0.1 1e-68 232.1 0.0 4.2 2 2 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KII83377.1 - 1.1e-06 28.7 0.9 0.77 10.5 0.0 6.2 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII83377.1 - 3.8e-05 23.9 0.5 0.88 9.9 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII83377.1 - 0.0015 18.8 2.6 0.35 11.4 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII83377.1 - 0.019 15.6 2.8 2.4 8.9 0.0 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat EFF-AFF PF14884.1 KII83377.1 - 0.13 10.3 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen TPR_11 PF13414.1 KII83377.1 - 0.18 11.4 1.1 1 9.0 0.2 2.5 3 0 0 3 3 3 0 TPR repeat AAA PF00004.24 KII83379.1 - 3.2e-47 160.0 0.0 3.3e-41 140.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII83379.1 - 8.6e-07 29.1 0.0 4.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KII83379.1 - 6e-06 25.7 0.0 5.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KII83379.1 - 2.6e-05 24.2 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KII83379.1 - 3.6e-05 23.9 0.1 0.0032 17.6 0.0 3.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KII83379.1 - 0.00044 19.9 1.2 0.0059 16.3 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 KII83379.1 - 0.00053 19.7 0.1 0.0035 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KII83379.1 - 0.0032 17.3 0.0 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII83379.1 - 0.0043 17.8 0.1 0.028 15.2 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KII83379.1 - 0.005 16.2 0.0 0.11 11.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KII83379.1 - 0.0082 16.1 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KII83379.1 - 0.011 16.0 0.9 0.045 14.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 KII83379.1 - 0.022 14.0 0.0 0.076 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.11 KII83379.1 - 0.026 13.3 0.0 0.38 9.5 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_28 PF13521.1 KII83379.1 - 0.028 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KII83379.1 - 0.052 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KII83379.1 - 0.06 12.5 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KII83379.1 - 0.07 12.5 0.0 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KII83379.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KII83379.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KII83379.1 - 0.094 11.4 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 KII83379.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 KII83379.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KII83379.1 - 0.28 10.8 0.1 0.77 9.3 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Torsin PF06309.6 KII83379.1 - 0.52 10.2 0.0 2.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Torsin DAO PF01266.19 KII83380.1 - 3.9e-43 147.7 1.9 4.7e-43 147.4 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII83380.1 - 6.1e-06 26.4 0.0 0.0002 21.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII83380.1 - 2e-05 24.5 0.1 4.9e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII83380.1 - 0.00025 20.2 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KII83380.1 - 0.0019 17.1 0.1 0.0028 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII83380.1 - 0.0063 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII83380.1 - 0.0067 16.2 0.1 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KII83380.1 - 0.061 12.3 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KII83380.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KII83380.1 - 0.067 11.8 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pkinase PF00069.20 KII83381.1 - 5.5e-08 32.2 0.0 9.2e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII83381.1 - 1.9e-07 31.0 0.1 0.00075 19.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII83381.1 - 0.0018 17.4 0.1 0.0056 15.7 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII83381.1 - 0.0072 15.4 0.1 0.064 12.3 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KII83382.1 - 0.00042 19.5 0.0 0.00079 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII83382.1 - 0.00099 18.1 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KII83382.1 - 0.0056 15.7 0.1 0.11 11.5 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 KII83383.1 - 0.061 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_sulf_C PF12411.3 KII83383.1 - 0.077 12.8 0.1 0.24 11.2 0.1 1.9 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal MFS_1 PF07690.11 KII83384.1 - 3.4e-38 131.2 47.0 5.7e-38 130.5 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII83384.1 - 3.7e-09 35.6 12.1 3.7e-09 35.6 8.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KII83384.1 - 4.6e-07 28.4 0.4 4.6e-07 28.4 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex2_Pex12 PF04757.9 KII83384.1 - 0.057 12.8 0.2 0.057 12.8 0.2 1.7 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF4538 PF15061.1 KII83384.1 - 4.3 6.7 5.7 1.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) AAA PF00004.24 KII83387.1 - 2.1e-93 309.4 0.0 2.5e-47 160.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KII83387.1 - 1.8e-15 56.6 0.0 2.6e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KII83387.1 - 1.7e-12 47.6 0.4 0.0039 17.3 0.0 5.1 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KII83387.1 - 5.5e-12 46.0 1.6 0.00025 21.0 0.1 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KII83387.1 - 3.7e-11 43.8 0.0 4.2e-06 27.5 0.0 2.7 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KII83387.1 - 1.2e-10 41.4 0.0 6e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KII83387.1 - 2e-10 40.5 0.8 0.00056 19.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KII83387.1 - 5.9e-10 39.3 0.0 0.00093 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KII83387.1 - 2.4e-09 37.1 0.0 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KII83387.1 - 8.7e-09 34.5 0.0 0.00012 20.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 KII83387.1 - 1.3e-08 34.2 0.0 0.0057 15.7 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin RNA_helicase PF00910.17 KII83387.1 - 5.9e-08 32.8 0.0 0.018 15.2 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KII83387.1 - 5.9e-08 32.3 0.0 0.009 15.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KII83387.1 - 1.3e-07 31.2 1.1 0.029 14.1 0.1 3.7 4 0 0 4 4 2 2 Part of AAA domain Mg_chelatase PF01078.16 KII83387.1 - 3.1e-07 29.7 0.4 0.02 14.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KII83387.1 - 5.9e-07 29.5 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KII83387.1 - 8.3e-07 28.5 4.2 0.6 9.4 0.0 4.4 2 2 2 4 4 4 2 AAA domain NACHT PF05729.7 KII83387.1 - 2.1e-06 27.4 0.8 0.17 11.4 0.0 3.8 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 KII83387.1 - 4.4e-06 26.3 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KII83387.1 - 6.5e-06 26.4 0.0 0.15 12.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_18 PF13238.1 KII83387.1 - 9.5e-06 25.9 0.0 0.092 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 KII83387.1 - 1.7e-05 24.0 0.1 0.36 9.8 0.0 3.2 2 1 1 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 KII83387.1 - 2.3e-05 24.4 0.0 0.42 10.6 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 KII83387.1 - 4.1e-05 23.1 0.0 0.38 10.2 0.0 3.7 4 1 0 4 4 3 2 Sigma-54 interaction domain SKI PF01202.17 KII83387.1 - 0.00016 21.5 0.0 0.62 9.9 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase DUF815 PF05673.8 KII83387.1 - 0.00025 20.0 0.0 0.012 14.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PhoH PF02562.11 KII83387.1 - 0.00029 20.1 0.2 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Cytidylate_kin2 PF13189.1 KII83387.1 - 0.00035 20.5 0.0 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 KII83387.1 - 0.00069 19.1 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KII83387.1 - 0.00075 18.4 0.0 0.37 9.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KII83387.1 - 0.0013 18.4 0.0 2.1 8.0 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase Rad17 PF03215.10 KII83387.1 - 0.0017 17.1 0.0 0.51 8.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 KII83387.1 - 0.002 17.7 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KII83387.1 - 0.0039 16.1 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 KII83387.1 - 0.0055 16.2 0.0 0.77 9.2 0.0 2.8 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 KII83387.1 - 0.011 15.3 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KII83387.1 - 0.012 15.1 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KII83387.1 - 0.029 14.0 0.0 2.1 8.0 0.0 2.7 2 1 0 2 2 2 0 NTPase DUF2075 PF09848.4 KII83387.1 - 0.029 13.3 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 KII83387.1 - 0.034 14.0 0.0 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SRPRB PF09439.5 KII83387.1 - 0.04 13.1 0.0 8.9 5.4 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AFG1_ATPase PF03969.11 KII83387.1 - 0.064 12.0 0.0 4.1 6.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.4 KII83387.1 - 0.091 12.2 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 KII83387.1 - 0.097 12.4 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 KII83387.1 - 0.12 11.3 0.0 6.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 KII83387.1 - 0.17 11.4 0.0 4 7.0 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein IPT PF01745.11 KII83387.1 - 0.18 10.9 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 KII83387.1 - 0.2 11.0 0.4 28 3.9 0.0 3.0 3 1 0 3 3 3 0 AAA-like domain Zn_clus PF00172.13 KII83390.1 - 0.4 10.6 12.1 0.78 9.7 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_2 PF13532.1 KII83392.1 - 0.036 13.9 0.0 0.095 12.5 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RCC1 PF00415.13 KII83393.1 - 5.6e-35 119.3 16.6 1.9e-12 47.2 0.2 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII83393.1 - 6.6e-20 70.1 28.2 1.7e-07 30.6 0.9 6.6 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 KII83393.1 - 8.9e-11 41.3 5.6 8.9e-11 41.3 3.9 2.5 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KII83393.1 - 0.0003 20.4 2.8 0.0003 20.4 1.9 2.4 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KII83393.1 - 0.00091 18.9 0.3 0.0036 17.0 0.2 2.0 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 KII83393.1 - 0.2 11.7 4.3 0.39 10.8 1.6 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger PHD_2 PF13831.1 KII83393.1 - 0.23 10.7 5.6 0.44 9.8 0.5 3.0 3 0 0 3 3 3 0 PHD-finger DNA_RNApol_7kD PF03604.8 KII83393.1 - 0.33 10.4 1.7 1.2 8.6 1.2 2.0 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Prim_Zn_Ribbon PF08273.7 KII83393.1 - 0.69 10.0 5.9 29 4.8 0.0 4.3 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase ThiF PF00899.16 KII83394.1 - 2e-32 111.8 0.0 5.1e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 KII83394.1 - 0.0027 17.8 0.0 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KII83394.1 - 0.16 11.1 0.0 0.9 8.6 0.0 2.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KII83394.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pkinase PF00069.20 KII83397.1 - 3.3e-08 33.0 0.0 5.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII83397.1 - 2.1e-05 24.4 0.1 0.014 15.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII83397.1 - 0.00051 19.1 0.0 0.0017 17.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII83397.1 - 0.00052 19.1 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gal-3-0_sulfotr PF06990.6 KII83400.1 - 0.026 13.1 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase F-box-like PF12937.2 KII83402.1 - 0.08 12.6 0.4 0.22 11.2 0.3 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 KII83402.1 - 0.1 12.3 0.5 0.23 11.1 0.3 1.6 1 0 0 1 1 1 0 F-box domain DUF4040 PF13244.1 KII83403.1 - 0.016 15.2 0.2 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) HD-ZIP_N PF04618.7 KII83406.1 - 1.7 9.1 6.1 4 8.0 4.1 1.6 1 1 1 2 2 2 0 HD-ZIP protein N terminus SIP PF04954.8 KII83407.1 - 0.021 15.1 2.7 0.031 14.6 1.8 1.4 1 1 0 1 1 1 0 Siderophore-interacting protein TraD PF06412.6 KII83407.1 - 0.054 13.0 3.8 0.062 12.9 1.4 1.8 2 0 0 2 2 2 0 Conjugal transfer protein TraD Abhydrolase_6 PF12697.2 KII83408.1 - 1.4e-30 106.8 0.4 1.4e-30 106.8 0.3 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII83408.1 - 2.2e-16 60.1 0.3 2.6e-14 53.3 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KII83408.1 - 0.01 15.6 0.1 0.11 12.3 0.0 2.7 2 1 0 2 2 2 0 Putative lysophospholipase F-box-like PF12937.2 KII83409.1 - 0.039 13.6 1.5 0.052 13.2 0.2 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KII83409.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cupin_2 PF07883.6 KII83409.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin domain F-box-like PF12937.2 KII83410.1 - 3.2e-08 33.1 0.4 6.4e-08 32.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII83411.1 - 0.037 13.7 2.6 0.044 13.5 0.3 2.2 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KII83412.1 - 7.4e-09 35.1 0.3 1.7e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII83412.1 - 3.1 7.5 5.7 19 5.0 1.7 3.2 2 1 0 2 2 2 0 F-box domain Methyltransf_20 PF12147.3 KII83413.1 - 0.096 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase F-box-like PF12937.2 KII83414.1 - 0.11 12.2 1.4 0.22 11.2 0.4 2.0 2 0 0 2 2 2 0 F-box-like RFC1 PF08519.7 KII83418.1 - 1.3e-52 177.6 0.0 3.4e-50 169.8 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KII83418.1 - 7.9e-13 48.3 0.0 2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KII83418.1 - 1.9e-08 34.5 0.0 5.5e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KII83418.1 - 3.6e-05 22.6 0.1 0.00022 20.0 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KII83418.1 - 0.0027 17.8 0.0 0.0074 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII83418.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KII83418.1 - 0.005 17.6 0.4 0.093 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KII83418.1 - 0.025 14.2 0.2 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 KII83418.1 - 0.036 13.6 2.4 0.036 13.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KII83418.1 - 0.037 13.9 0.2 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KII83418.1 - 0.058 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KII83418.1 - 0.063 12.3 0.0 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KII83418.1 - 0.075 12.9 0.0 0.32 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KII83418.1 - 0.089 13.1 1.4 0.26 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.4 KII83419.1 - 1.1 8.6 4.8 2.1 7.7 3.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3363 PF11843.3 KII83423.1 - 0.041 12.5 1.0 0.042 12.5 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) Tet_JBP PF12851.2 KII83425.1 - 2.6e-05 23.5 0.0 3.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily XRN_N PF03159.13 KII83426.1 - 0.2 11.0 0.6 0.31 10.4 0.4 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Cauli_VI PF01693.11 KII83427.1 - 1.7e-06 27.9 1.1 2.2e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Caulimovirus viroplasmin FAP PF07174.6 KII83427.1 - 7.4 5.7 15.5 9.9 5.3 10.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DinB_2 PF12867.2 KII83428.1 - 0.13 12.6 2.1 0.4 11.0 1.5 2.1 1 1 0 1 1 1 0 DinB superfamily Snapin_Pallidin PF14712.1 KII83429.1 - 0.035 14.4 1.4 0.035 14.4 1.0 2.6 3 0 0 3 3 3 0 Snapin/Pallidin DUF3166 PF11365.3 KII83429.1 - 0.043 14.2 4.0 0.27 11.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Myosin_tail_1 PF01576.14 KII83429.1 - 0.053 11.2 13.9 0.085 10.5 9.6 1.3 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 KII83429.1 - 0.15 11.6 19.2 0.22 11.1 7.2 2.6 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 KII83429.1 - 0.19 11.5 8.0 0.72 9.7 5.3 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EURL PF06937.6 KII83429.1 - 0.63 9.4 5.8 0.93 8.8 4.0 1.2 1 0 0 1 1 1 0 EURL protein AAA_13 PF13166.1 KII83429.1 - 0.67 8.3 5.1 0.28 9.6 1.2 1.7 1 1 1 2 2 2 0 AAA domain Mnd1 PF03962.10 KII83429.1 - 0.99 9.0 9.3 26 4.4 4.8 2.8 2 1 1 3 3 3 0 Mnd1 family Ead_Ea22 PF13935.1 KII83429.1 - 2.1 8.6 9.6 0.36 11.1 1.0 2.7 1 1 1 2 2 2 0 Ead/Ea22-like protein 7TMR-HDED PF07697.6 KII83429.1 - 3.1 7.4 13.3 4.6 6.9 9.2 1.2 1 0 0 1 1 1 0 7TM-HD extracellular HALZ PF02183.13 KII83429.1 - 4.1 7.2 10.3 6.8 6.4 0.0 4.7 4 1 1 5 5 5 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 KII83429.1 - 4.5 7.1 10.4 0.28 11.0 1.5 2.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KII83429.1 - 8.3 5.2 17.3 9.4 5.0 10.5 2.0 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_ORF11 PF04797.8 KII83431.1 - 0.021 13.2 0.0 0.029 12.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Chromo PF00385.19 KII83434.1 - 1e-12 47.5 0.0 1.1e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.9 KII83438.1 - 3.9e-06 26.3 0.0 6.6e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region INTS5_N PF14837.1 KII83441.1 - 0.0023 17.3 0.0 0.0029 17.0 0.0 1.0 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus LIN37 PF15306.1 KII83443.1 - 0.45 10.5 2.2 0.51 10.3 1.6 1.1 1 0 0 1 1 1 0 LIN37 BUD22 PF09073.5 KII83443.1 - 1.4 7.9 11.2 1.7 7.5 7.7 1.1 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 KII83443.1 - 9.7 5.3 13.5 11 5.1 9.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RhoGAP PF00620.22 KII83448.1 - 0.00056 19.5 0.0 0.0023 17.5 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain DUF3376 PF11856.3 KII83455.1 - 0.084 12.2 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Dimer_Tnp_hAT PF05699.9 KII83456.1 - 0.00024 20.6 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cwf_Cwc_15 PF04889.7 KII83456.1 - 0.4 10.3 6.1 0.59 9.8 4.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pap_E4 PF02711.9 KII83456.1 - 2.3 9.0 4.6 5.5 7.8 3.3 1.7 1 1 0 1 1 1 0 E4 protein MRI PF15325.1 KII83456.1 - 8.7 7.3 10.7 6.6 7.7 5.8 1.8 1 1 1 2 2 2 0 Modulator of retrovirus infection DUF4186 PF13811.1 KII83461.1 - 0.015 14.9 0.7 0.022 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) GAS PF13851.1 KII83461.1 - 0.042 13.0 0.7 0.047 12.8 0.5 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Apis_Csd PF11671.3 KII83461.1 - 0.11 12.2 4.1 0.15 11.8 2.9 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein Radial_spoke_3 PF06098.6 KII83461.1 - 1.2 8.0 4.2 1.3 8.0 2.9 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Tet_JBP PF12851.2 KII83463.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 KII83463.1 - 0.12 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KII83466.1 - 1.3e-07 31.0 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII83466.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KII83467.1 - 2.8e-32 111.8 0.0 3.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII83467.1 - 3.5e-05 23.0 0.0 6.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII83467.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KII83467.1 - 0.063 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polyhedrin PF00738.13 KII83467.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Polyhedrin APH PF01636.18 KII83467.1 - 0.1 12.3 0.1 0.29 10.8 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KII83467.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribonuc_red_sm PF00268.16 KII83468.1 - 6.1e-55 186.2 0.0 7.3e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Methyltransf_23 PF13489.1 KII83475.1 - 4.7e-13 49.1 0.0 6.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII83475.1 - 9.9e-09 34.9 0.0 6.1e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII83475.1 - 3.7e-08 33.7 0.0 5.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII83475.1 - 1.7e-05 25.2 0.0 5.6e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII83475.1 - 5.9e-05 23.6 0.0 0.0003 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KII83475.1 - 7.6e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 KII83475.1 - 0.00021 21.6 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KII83475.1 - 0.0009 17.6 0.0 0.072 11.4 0.0 2.0 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KII83475.1 - 0.0019 17.3 0.0 0.028 13.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KII83475.1 - 0.0042 16.7 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 KII83475.1 - 0.0059 15.6 0.0 0.042 12.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KII83475.1 - 0.014 14.8 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.15 KII83475.1 - 0.014 14.4 0.0 0.068 12.2 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 KII83475.1 - 0.051 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ribosomal_L13e PF01294.13 KII83479.1 - 0.22 10.9 3.6 0.33 10.4 2.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e DUF2797 PF10977.3 KII83485.1 - 0.39 10.2 2.8 0.62 9.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Scaffolding_pro PF11418.3 KII83491.1 - 0.013 15.7 0.3 0.065 13.5 0.1 2.3 1 1 1 2 2 2 0 Phi29 scaffolding protein DUF3166 PF11365.3 KII83491.1 - 0.039 14.3 11.4 0.09 13.2 1.5 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3166) DUF972 PF06156.8 KII83491.1 - 0.39 11.0 9.6 0.83 10.0 1.5 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 KII83491.1 - 1.1 9.1 18.2 2.6 7.9 6.3 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1515 PF07439.6 KII83491.1 - 1.4 8.7 14.6 0.8 9.5 1.7 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.7 KII83491.1 - 4 7.1 24.1 6.4 6.5 3.7 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 KII83491.1 - 5 6.9 33.4 0.19 11.5 12.3 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Atg14 PF10186.4 KII83491.1 - 5.1 5.9 23.5 1.4 7.8 10.9 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KII83491.1 - 7 6.4 18.8 0.84 9.4 8.0 2.5 2 1 0 2 2 2 0 Tropomyosin like Mto2_bdg PF12808.2 KII83493.1 - 0.0034 17.4 3.8 0.0074 16.3 2.6 1.5 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Mac PF12464.3 KII83493.1 - 0.24 11.4 6.2 0.56 10.2 0.6 2.8 2 1 0 2 2 2 0 Maltose acetyltransferase DUF904 PF06005.7 KII83505.1 - 0.011 16.0 1.9 0.011 16.0 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 KII83505.1 - 0.24 10.5 3.3 4.2 6.4 1.3 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KII83505.1 - 0.41 11.0 7.5 1.6 9.1 1.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF3166 PF11365.3 KII83505.1 - 0.42 11.0 8.2 1.4 9.4 1.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3166) IncA PF04156.9 KII83505.1 - 0.46 10.0 27.0 0.58 9.7 3.5 3.2 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 KII83505.1 - 0.93 9.3 15.0 4 7.3 5.6 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1515 PF07439.6 KII83505.1 - 1.9 8.3 12.9 0.35 10.7 0.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1515) Spc7 PF08317.6 KII83505.1 - 3.3 6.2 7.6 2.2 6.8 3.5 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Spc7 PF08317.6 KII83508.1 - 0.014 14.0 6.6 0.026 13.1 4.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.4 KII83508.1 - 0.015 13.6 3.0 0.018 13.3 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein HALZ PF02183.13 KII83508.1 - 0.058 13.1 0.5 0.28 10.9 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pox_A_type_inc PF04508.7 KII83508.1 - 0.078 12.7 2.3 1.3 8.9 0.1 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NYD-SP28_assoc PF14775.1 KII83508.1 - 0.21 11.2 1.1 0.59 9.8 0.8 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain IncA PF04156.9 KII83508.1 - 0.28 10.7 17.3 0.11 12.0 2.8 2.7 2 1 1 3 3 3 0 IncA protein AAA_13 PF13166.1 KII83508.1 - 0.93 7.8 3.4 1.4 7.2 2.4 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KII83508.1 - 9.6 5.1 10.5 8.3 5.3 6.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Peptidase_C48 PF02902.14 KII83509.1 - 0.00018 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEAD PF00270.24 KII83513.1 - 2.5e-14 53.1 0.0 5.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII83513.1 - 1.6e-08 34.2 0.1 1.6e-08 34.2 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII83513.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RVT_1 PF00078.22 KII83516.1 - 0.0044 16.3 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 KII83516.1 - 0.015 15.5 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase CAF-1_p150 PF11600.3 KII83517.1 - 6.9 5.9 27.4 53 3.0 19.0 2.0 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cyclin PF08613.6 KII83520.1 - 3e-06 27.6 0.2 5.6e-06 26.8 0.1 1.3 1 1 0 1 1 1 1 Cyclin RCC1 PF00415.13 KII83524.1 - 1.4e-37 127.6 10.7 2.5e-09 37.1 0.2 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII83524.1 - 4.9e-26 89.7 25.0 6.3e-08 32.0 0.3 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat AvrE PF11725.3 KII83524.1 - 0.021 11.8 0.0 0.024 11.6 0.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor F-box-like PF12937.2 KII83525.1 - 0.037 13.7 0.3 0.14 11.9 0.0 2.1 3 0 0 3 3 3 0 F-box-like Rubi_NSP_C PF12601.3 KII83527.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Rubivirus non-structural protein DDE_1 PF03184.14 KII83531.1 - 4.1e-32 111.0 0.0 1.3e-31 109.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KII83531.1 - 1.7e-06 27.7 0.9 1.7e-06 27.7 0.6 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 KII83531.1 - 0.00028 20.6 0.0 0.0008 19.1 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease CAF-1_p150 PF11600.3 KII83531.1 - 0.44 9.8 9.4 0.018 14.3 2.6 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal adh_short PF00106.20 KII83532.1 - 6.7e-16 58.6 2.8 6.7e-16 58.6 1.9 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII83532.1 - 1.3e-05 24.9 0.3 1.6e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.18 KII83533.1 - 2.6e-76 256.5 0.0 2.9e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain GHMP_kinases_C PF08544.8 KII83538.1 - 0.00021 21.3 0.0 0.00052 20.1 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal NFRKB_winged PF14465.1 KII83538.1 - 0.1 12.4 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like WXG100 PF06013.7 KII83538.1 - 0.13 12.2 0.6 0.3 11.1 0.2 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Fungal_trans PF04082.13 KII83542.1 - 3.8e-17 62.0 0.1 7.4e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII83542.1 - 5.7e-06 26.1 11.1 9.8e-06 25.3 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecl1 PF12855.2 KII83543.1 - 9.3e-05 21.6 1.0 0.044 13.0 0.0 2.6 3 0 0 3 3 3 2 Life-span regulatory factor Tox-HNH-EHHH PF15657.1 KII83545.1 - 0.16 12.1 1.6 0.82 9.8 1.1 2.0 1 1 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins AflR PF08493.5 KII83545.1 - 0.37 9.7 2.7 0.43 9.5 1.9 1.0 1 0 0 1 1 1 0 Aflatoxin regulatory protein MANEC PF07502.9 KII83546.1 - 0.056 13.4 1.2 0.1 12.5 0.8 1.3 1 0 0 1 1 1 0 MANEC domain Glyco_hyd_65N_2 PF14498.1 KII83548.1 - 0.11 12.2 4.1 0.089 12.4 1.9 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sec20 PF03908.8 KII83548.1 - 0.48 10.1 11.9 0.22 11.2 0.4 2.9 3 0 0 3 3 3 0 Sec20 Flu_NS2 PF00601.14 KII83548.1 - 4 7.7 6.0 2.4 8.4 0.5 2.9 1 1 1 3 3 3 0 Influenza non-structural protein (NS2) zf-MYND PF01753.13 KII83550.1 - 2.3e-06 27.3 10.0 4.8e-06 26.3 6.9 1.5 1 0 0 1 1 1 1 MYND finger RseC_MucC PF04246.7 KII83550.1 - 0.23 11.0 2.2 0.44 10.1 1.5 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC UBN2_3 PF14244.1 KII83559.1 - 0.00016 21.2 0.0 0.00039 20.0 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KII83559.1 - 0.028 13.8 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) UBN2 PF14223.1 KII83560.1 - 1e-08 34.9 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII83560.1 - 0.00028 20.6 4.7 0.00058 19.6 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 KII83560.1 - 0.00066 19.2 0.0 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1877 PF08974.5 KII83560.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) zf-CCHC_4 PF14392.1 KII83560.1 - 0.29 10.8 1.4 0.59 9.8 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 KII83561.1 - 1.1e-11 44.4 0.0 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII83561.1 - 7.2e-07 28.7 0.0 7.7e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1877 PF08974.5 KII83561.1 - 0.016 14.9 0.1 0.045 13.4 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1877) UBN2_3 PF14244.1 KII83561.1 - 0.074 12.6 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NUDE_C PF04880.8 KII83566.1 - 0.49 10.7 5.7 2.3 8.5 3.5 2.0 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region BAT2_N PF07001.6 KII83566.1 - 0.93 9.8 7.5 1.1 9.6 4.7 1.5 1 1 0 1 1 1 0 BAT2 N-terminus DUF605 PF04652.11 KII83566.1 - 2.6 7.3 12.5 3.3 6.9 8.7 1.1 1 0 0 1 1 1 0 Vta1 like Deltaretro_Tax PF05599.6 KII83568.1 - 0.012 15.8 0.1 0.039 14.2 0.1 1.9 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Helicase_C PF00271.26 KII83572.1 - 1.7e-13 50.1 0.0 1.3e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Alveol-reg_P311 PF11092.3 KII83572.1 - 0.052 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) DUF2763 PF10961.3 KII83578.1 - 1.9 8.9 5.7 3.2 8.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) zf-CCHC PF00098.18 KII83581.1 - 0.88 9.6 2.5 1.5 8.8 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle TraB PF01963.12 KII83584.1 - 0.16 11.3 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 TraB family Retrotrans_gag PF03732.12 KII83591.1 - 0.012 15.6 0.0 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 KII83591.1 - 0.013 15.9 0.3 0.23 12.0 0.1 3.1 3 1 0 3 3 3 0 Aspartyl protease RVP_2 PF08284.6 KII83591.1 - 0.04 13.8 0.1 0.87 9.5 0.0 2.3 1 1 0 1 1 1 0 Retroviral aspartyl protease NACHT PF05729.7 KII83593.1 - 1.2e-08 34.7 0.0 3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KII83593.1 - 8.1e-06 24.9 0.0 1.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KII83593.1 - 2.4e-05 24.4 0.0 0.00013 21.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KII83593.1 - 0.0059 16.8 0.0 0.021 15.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KII83593.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.15 KII83593.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 KII83593.1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII83593.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Patatin PF01734.17 KII83594.1 - 3.5e-17 63.0 0.0 5.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DNA_pol_viral_N PF00242.12 KII83597.1 - 0.25 10.3 1.8 0.29 10.1 1.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ish1 PF10281.4 KII83599.1 - 1.5e-37 127.2 26.6 1.3e-08 34.7 1.4 7.6 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KII83599.1 - 1.7e-05 24.1 0.0 1.1 8.8 0.0 4.7 6 0 0 6 6 6 2 SAP domain HeH PF12949.2 KII83599.1 - 0.00088 18.7 1.3 4.3 6.9 0.0 4.1 4 0 0 4 4 4 2 HeH/LEM domain APC2 PF08672.6 KII83599.1 - 0.0026 18.0 0.1 24 5.2 0.0 5.2 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 DUF1939 PF09154.5 KII83599.1 - 0.031 14.1 0.2 0.19 11.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) SAM_2 PF07647.12 KII83599.1 - 0.066 13.0 9.4 3.4 7.5 0.1 5.1 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) Slx4 PF09494.5 KII83599.1 - 0.083 12.6 1.5 8.8 6.1 0.0 4.1 5 0 0 5 5 5 0 Slx4 endonuclease ApoLp-III PF07464.6 KII83601.1 - 0.038 14.0 0.5 0.08 12.9 0.3 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) NACHT PF05729.7 KII83602.1 - 9e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII83602.1 - 7.5e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KII83602.1 - 4.8e-05 22.3 0.0 5.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KII83602.1 - 0.0017 18.5 0.0 0.002 18.2 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KII83602.1 - 0.0021 17.7 0.2 0.0091 15.6 0.1 1.9 1 1 1 2 2 2 1 Adenylylsulphate kinase NTPase_1 PF03266.10 KII83602.1 - 0.0027 17.4 0.0 0.0031 17.2 0.0 1.4 1 1 0 1 1 1 1 NTPase AAA_18 PF13238.1 KII83602.1 - 0.003 17.8 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KII83602.1 - 0.0038 16.9 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KII83602.1 - 0.0067 17.2 0.1 0.0075 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KII83602.1 - 0.0069 16.2 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KII83602.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KII83602.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 KII83602.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KII83602.1 - 0.055 13.3 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KII83602.1 - 0.065 12.5 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase IstB_IS21 PF01695.12 KII83602.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein WD40 PF00400.27 KII83603.1 - 2.3e-123 398.1 37.4 3.4e-14 52.0 0.1 9.3 9 0 0 9 9 9 9 WD domain, G-beta repeat PD40 PF07676.7 KII83603.1 - 1e-13 50.6 12.9 3.5 7.3 0.0 9.2 9 0 0 9 9 9 7 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KII83603.1 - 1.7e-08 33.1 0.0 0.15 10.2 0.0 5.5 1 1 7 8 8 8 6 Protein of unknown function (DUF3312) Nup160 PF11715.3 KII83603.1 - 2e-05 22.9 10.5 2 6.4 0.0 6.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 KII83603.1 - 0.00025 20.2 0.2 6.4 5.7 0.0 4.9 1 1 5 7 7 7 1 Protein of unknown function (DUF1258) DUF374 PF04028.8 KII83603.1 - 0.0013 17.9 7.7 11 5.3 0.0 6.3 4 2 3 7 7 7 1 Domain of unknown function (DUF374) AsnC_trans_reg PF01037.16 KII83603.1 - 0.18 11.5 0.8 43 3.9 0.0 4.4 5 0 0 5 5 5 0 AsnC family Vif PF00559.12 KII83604.1 - 0.00091 19.1 0.1 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral Vif (Viral infectivity) protein NACHT PF05729.7 KII83607.1 - 2.5e-09 37.0 0.0 7.3e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KII83607.1 - 8.3e-07 29.1 0.1 6.2e-06 26.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 KII83607.1 - 0.00047 19.1 0.0 0.00088 18.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KII83607.1 - 0.0012 18.9 0.0 0.0083 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KII83607.1 - 0.0025 18.0 0.0 0.012 15.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KII83607.1 - 0.025 14.1 0.0 0.061 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KII83607.1 - 0.053 13.1 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.1 KII83607.1 - 0.1 12.4 0.2 3.5 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KII83607.1 - 0.16 11.6 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase WD40 PF00400.27 KII83608.1 - 1.3e-171 551.1 53.3 8e-14 50.9 0.1 13.2 13 0 0 13 13 13 13 WD domain, G-beta repeat Nup160 PF11715.3 KII83608.1 - 2.2e-17 62.4 21.1 0.27 9.3 0.1 11.3 1 1 10 11 11 11 9 Nucleoporin Nup120/160 DUF1258 PF06869.7 KII83608.1 - 2.1e-13 49.9 5.8 0.34 9.9 0.0 8.5 3 2 7 10 10 10 4 Protein of unknown function (DUF1258) PD40 PF07676.7 KII83608.1 - 2.4e-12 46.1 11.5 4.2 7.1 0.0 11.1 12 0 0 12 12 12 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KII83608.1 - 5.8e-10 38.0 0.0 1.7 6.8 0.0 7.4 4 3 4 9 9 9 3 Protein of unknown function (DUF3312) RicinB_lectin_2 PF14200.1 KII83608.1 - 1.3e-08 35.1 8.6 0.5 10.7 0.1 6.3 1 1 8 9 9 9 4 Ricin-type beta-trefoil lectin domain-like IKI3 PF04762.7 KII83608.1 - 1.8e-06 26.1 0.7 0.98 7.1 0.0 5.6 2 2 4 6 6 6 2 IKI3 family PQQ_3 PF13570.1 KII83608.1 - 0.00018 21.6 17.5 16 5.9 0.1 8.5 7 4 2 9 9 8 0 PQQ-like domain FrpC PF06901.7 KII83608.1 - 0.00078 19.0 0.3 13 5.2 0.0 4.5 4 3 0 4 4 4 0 RTX iron-regulated protein FrpC CbiG_N PF11760.3 KII83608.1 - 0.032 13.9 9.2 40 4.0 0.0 6.3 6 3 2 8 8 8 0 Cobalamin synthesis G N-terminal PQQ PF01011.16 KII83608.1 - 0.35 10.4 4.7 61 3.4 0.0 5.9 7 0 0 7 7 7 0 PQQ enzyme repeat PepSY PF03413.14 KII83608.1 - 6.1 7.5 6.0 2.7e+02 2.3 0.0 5.5 8 0 0 8 8 8 0 Peptidase propeptide and YPEB domain MSP1_C PF07462.6 KII83609.1 - 0.79 8.0 3.2 0.85 7.9 2.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PaaX_C PF08223.6 KII83610.1 - 0.051 13.2 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Trypan_PARP PF05887.6 KII83610.1 - 2.8 7.7 12.1 0.037 13.8 1.7 2.5 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.17 KII83611.1 - 2.3e-68 230.8 0.0 9.6e-68 228.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 NicO PF03824.11 KII83611.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein PPR_3 PF13812.1 KII83612.1 - 2.3e-13 49.2 6.8 0.014 15.6 0.0 5.6 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 KII83612.1 - 7.8e-06 25.7 0.0 0.19 11.7 0.0 4.6 4 2 2 6 6 6 2 PPR repeat family PPR_1 PF12854.2 KII83612.1 - 0.029 13.8 0.0 24 4.5 0.0 3.8 4 1 0 4 4 4 0 PPR repeat DUF1106 PF06523.6 KII83613.1 - 0.1 12.4 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Zn_clus PF00172.13 KII83614.1 - 4.8e-10 39.1 6.2 6.9e-10 38.6 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_2 PF13532.1 KII83615.1 - 2.4e-12 47.1 0.0 1.4e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.17 KII83616.1 - 5.7e-13 48.4 0.0 9.1e-12 44.5 0.0 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RNF111_N PF15303.1 KII83616.1 - 0.0034 16.9 0.6 0.0044 16.5 0.4 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus DUF2334 PF10096.4 KII83616.1 - 0.17 11.2 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) PEMT PF04191.8 KII83617.1 - 9.5e-49 163.9 17.3 8e-28 96.6 1.6 3.5 3 0 0 3 3 3 2 Phospholipid methyltransferase PID PF00640.18 KII83617.1 - 0.0037 17.2 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) DUF4199 PF13858.1 KII83617.1 - 0.012 15.5 0.1 1.4 8.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4197 PF13852.1 KII83617.1 - 0.045 13.2 0.2 0.078 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) UbiA PF01040.13 KII83620.1 - 1.9e-22 79.7 12.3 2.6e-22 79.2 8.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 KII83621.1 - 1.4e-69 234.7 0.0 1.8e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF_4G1 PF12152.3 KII83621.1 - 0.024 14.4 0.1 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Saccharop_dh PF03435.13 KII83622.1 - 4.3e-24 85.2 0.1 6.7e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KII83622.1 - 2.1e-05 24.6 0.4 3.4e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KII83622.1 - 3.5e-05 23.5 0.7 0.00014 21.5 0.6 1.8 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 KII83622.1 - 0.00037 20.7 0.1 0.00093 19.4 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KII83622.1 - 0.00043 19.6 0.2 0.00066 19.0 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII83622.1 - 0.0017 17.8 0.3 0.011 15.1 0.1 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KII83622.1 - 0.02 14.9 0.3 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KII83622.1 - 0.045 12.4 0.0 0.073 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GMC_oxred_N PF00732.14 KII83623.1 - 6e-64 216.0 0.0 7.6e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII83623.1 - 9.2e-38 129.7 0.0 1.8e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KII83623.1 - 4.9e-07 28.9 0.1 6.4e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KII83623.1 - 1.5e-05 24.8 0.3 4.3e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII83623.1 - 0.00038 19.4 0.5 0.00058 18.8 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KII83623.1 - 0.0004 19.3 2.8 0.0019 17.1 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII83623.1 - 0.00048 20.0 0.7 0.14 12.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII83623.1 - 0.0032 17.5 0.1 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 KII83625.1 - 2.6e-73 247.1 0.0 3.1e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KII83627.1 - 1.8e-07 30.5 0.0 3.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII83627.1 - 5e-05 22.4 0.0 9.3e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UbiA PF01040.13 KII83628.1 - 6.5e-23 81.2 8.0 9e-23 80.7 5.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Lon_C PF05362.8 KII83629.1 - 3.3e-66 222.5 0.4 5.4e-66 221.8 0.3 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KII83629.1 - 2.8e-22 79.3 0.0 6.6e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII83629.1 - 1.2e-10 41.2 0.0 6e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) LON PF02190.11 KII83629.1 - 1.4e-10 41.2 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 KII83629.1 - 2.1e-07 30.4 0.0 1.2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 KII83629.1 - 2.3e-05 24.3 0.0 7.5e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KII83629.1 - 0.00024 21.9 0.0 0.0011 19.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KII83629.1 - 0.00028 20.9 0.2 0.0019 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KII83629.1 - 0.0017 18.6 0.0 0.031 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KII83629.1 - 0.0019 17.2 0.0 0.018 14.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KII83629.1 - 0.0031 17.1 0.0 0.0093 15.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII83629.1 - 0.0036 17.4 0.3 0.19 11.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KII83629.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KII83629.1 - 0.024 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 KII83629.1 - 0.033 12.9 0.0 0.18 10.4 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus SKI PF01202.17 KII83629.1 - 0.037 13.9 0.3 0.092 12.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase AAA_25 PF13481.1 KII83629.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII83629.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII83629.1 - 0.085 12.5 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF1615 PF07759.7 KII83629.1 - 0.092 11.4 0.4 0.14 10.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) RNA_helicase PF00910.17 KII83629.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Git3_C PF11970.3 KII83630.1 - 0.019 14.7 0.3 0.047 13.4 0.2 1.6 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term GMC_oxred_N PF00732.14 KII83632.1 - 1.1e-60 205.3 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII83632.1 - 5.3e-41 140.2 0.0 9.1e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KII83632.1 - 2.3e-05 23.4 0.1 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KII83632.1 - 0.001 19.0 0.7 0.068 13.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII83632.1 - 0.0011 18.9 1.2 0.0023 17.9 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII83632.1 - 0.0018 17.2 4.4 0.009 14.9 1.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII83632.1 - 0.0057 15.6 0.2 0.0084 15.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KII83632.1 - 0.028 14.4 0.0 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gly_rich_SFCGS PF14272.1 KII83632.1 - 0.12 12.2 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycine-rich SFCGS GMC_oxred_N PF00732.14 KII83633.1 - 1.5e-59 201.5 0.0 2e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII83633.1 - 2.5e-37 128.3 0.0 4.2e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KII83633.1 - 7.2e-05 21.8 1.4 0.0005 19.0 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII83633.1 - 0.00048 20.0 1.4 0.0016 18.4 1.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII83633.1 - 0.0016 17.4 0.2 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KII83633.1 - 0.0058 16.5 0.1 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII83633.1 - 0.04 13.0 0.1 0.04 13.0 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 KII83633.1 - 0.11 11.3 4.2 0.041 12.7 1.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KII83633.1 - 0.15 11.0 0.9 0.25 10.3 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain CENP-Q PF13094.1 KII83634.1 - 0.0014 18.6 17.5 0.0014 18.6 12.1 5.6 2 2 2 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit CALCOCO1 PF07888.6 KII83634.1 - 0.0021 16.4 6.9 0.0021 16.4 4.8 3.2 1 1 2 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2968 PF11180.3 KII83634.1 - 0.0082 15.5 11.1 0.0082 15.5 7.7 5.6 3 1 2 6 6 6 3 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 KII83634.1 - 0.011 15.6 18.3 0.011 15.6 12.7 6.1 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 KII83634.1 - 0.21 11.0 42.0 0.048 13.1 3.3 5.4 2 1 3 5 5 5 0 Phage minor structural protein GP20 IncA PF04156.9 KII83634.1 - 1.2 8.6 93.2 0.077 12.5 10.8 5.7 1 1 4 5 5 5 0 IncA protein APG6 PF04111.7 KII83634.1 - 2 7.3 75.8 1.8 7.5 15.3 4.9 2 1 3 5 5 5 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KII83634.1 - 3.3 7.5 64.9 0.23 11.2 4.0 7.3 5 2 2 7 7 7 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 KII83634.1 - 4.8 7.0 15.3 2.5 7.8 2.6 3.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4592 PF15262.1 KII83638.1 - 7 7.2 13.1 2.2 8.8 2.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4592) PAP_assoc PF03828.14 KII83640.1 - 5e-18 64.7 0.1 9.3e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KII83640.1 - 1.8e-05 24.9 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 KII83640.1 - 0.028 13.2 0.0 4 6.1 0.0 2.4 2 0 0 2 2 2 0 Poly(A) polymerase central domain LSM PF01423.17 KII83642.1 - 6.8e-17 60.7 0.0 8.1e-17 60.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT PF02985.17 KII83643.1 - 6.4e-20 69.3 13.5 0.00028 20.7 0.0 11.0 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 KII83643.1 - 1.6e-19 69.7 12.0 3.1e-08 33.8 0.0 9.1 9 2 2 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 KII83643.1 - 1.1e-17 64.0 4.3 4.1e-06 26.9 0.0 7.9 2 1 6 8 8 8 6 HEAT repeats IBN_N PF03810.14 KII83643.1 - 7.6e-11 41.7 2.6 7.1e-10 38.6 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 KII83643.1 - 9.4e-08 31.6 7.0 0.00065 19.4 0.0 5.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KII83643.1 - 9e-06 25.2 0.0 4.3 6.6 0.0 4.6 2 1 2 4 4 4 3 CLASP N terminal DUF3385 PF11865.3 KII83643.1 - 0.0035 17.2 0.4 2.7 7.9 0.0 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) RIX1 PF08167.7 KII83643.1 - 0.76 9.4 3.9 21 4.7 0.0 4.1 4 1 2 6 6 6 0 rRNA processing/ribosome biogenesis Amino_oxidase PF01593.19 KII83644.1 - 1.6e-25 90.1 0.1 3.8e-19 69.1 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII83644.1 - 1.3e-08 34.7 0.0 4.1e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII83644.1 - 0.0045 17.0 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII83644.1 - 0.077 12.0 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KII83644.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.17 KII83645.1 - 1.3e-55 188.8 0.0 1.7e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cullin_binding PF03556.10 KII83650.1 - 3.7e-35 120.6 0.3 7.3e-35 119.6 0.2 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KII83650.1 - 6e-07 28.8 0.0 1.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-DHHC PF01529.15 KII83651.1 - 1.5e-35 122.1 15.9 1.5e-35 122.1 11.0 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 KII83651.1 - 0.025 14.3 2.1 0.025 14.3 1.4 2.2 3 0 0 3 3 3 0 Double zinc ribbon DUF1282 PF06930.7 KII83651.1 - 0.03 13.9 0.6 0.03 13.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) DUF165 PF02592.10 KII83651.1 - 0.062 13.4 2.0 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 DUF912 PF06024.7 KII83651.1 - 0.13 12.2 0.1 0.49 10.4 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YSIRK_signal PF04650.12 KII83651.1 - 0.19 11.3 0.3 0.38 10.3 0.2 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide HALZ PF02183.13 KII83654.1 - 0.00052 19.6 0.3 0.001 18.7 0.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 KII83654.1 - 0.0036 17.6 0.3 0.0078 16.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF2205 PF10224.4 KII83654.1 - 0.027 14.0 0.7 0.051 13.1 0.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Transposase_21 PF02992.9 KII83655.1 - 1.7e-09 37.1 0.0 4.1e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 KII83655.1 - 0.031 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Aminotran_3 PF00202.16 KII83657.1 - 9.1e-99 330.5 0.0 1.1e-98 330.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KII83657.1 - 0.0038 16.3 0.0 0.012 14.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KII83657.1 - 0.0078 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II F-box-like PF12937.2 KII83658.1 - 2.9e-07 30.1 1.1 5.7e-07 29.1 0.7 1.5 1 1 0 1 1 1 1 F-box-like TMV_coat PF00721.16 KII83658.1 - 0.04 13.8 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Virus coat protein (TMV like) DUF4150 PF13665.1 KII83659.1 - 0.028 14.3 2.8 0.16 11.8 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4150) FtsH_ext PF06480.10 KII83659.1 - 0.12 12.5 0.3 8 6.6 0.0 2.6 2 1 0 2 2 2 0 FtsH Extracellular CTP_transf_2 PF01467.21 KII83660.1 - 1.1e-16 61.2 0.0 2.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase CagX PF03524.10 KII83660.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Amidohydro_3 PF07969.6 KII83661.1 - 1.4e-75 255.0 0.2 1.7e-75 254.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KII83661.1 - 0.0014 18.7 2.5 0.88 9.5 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KII83661.1 - 0.0046 16.6 0.4 0.38 10.3 0.0 2.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KII83661.1 - 0.0099 15.6 0.0 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Histone PF00125.19 KII83662.1 - 1.4e-22 79.5 0.1 1.9e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII83662.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 KII83663.1 - 1e-70 233.4 5.6 5.6e-23 80.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GMC_oxred_N PF00732.14 KII83664.1 - 4.7e-64 216.3 0.0 6.6e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII83664.1 - 2.2e-35 122.0 0.0 3.9e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KII83664.1 - 3.1e-05 23.0 0.1 4.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KII83664.1 - 0.0036 16.1 1.0 0.02 13.7 0.7 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII83664.1 - 0.013 15.3 0.1 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII83664.1 - 0.019 14.0 0.1 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KII83664.1 - 0.034 13.0 0.6 0.32 9.8 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KII83664.1 - 0.2 10.0 0.8 0.31 9.4 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KII83664.1 - 0.27 10.0 0.1 1.4 7.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF4218 PF13960.1 KII83669.1 - 2.3e-07 30.3 0.0 3.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 KII83669.1 - 4.9e-07 29.0 0.0 9e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Auto_anti-p27 PF06677.7 KII83669.1 - 0.013 15.2 2.4 1.3 8.7 0.1 2.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_3 PF13920.1 KII83669.1 - 0.35 10.5 13.6 0.069 12.8 2.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3987 PF13148.1 KII83669.1 - 0.6 8.6 6.2 2.3 6.6 1.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) zf-C2HC5 PF06221.8 KII83669.1 - 4.6 7.0 7.7 2.6 7.8 0.2 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.2 KII83669.1 - 10 6.0 10.6 19 5.1 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon HEM4 PF02602.10 KII83671.1 - 9.6e-37 126.4 0.0 1.1e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Zn_clus PF00172.13 KII83672.1 - 1.2e-05 25.0 8.2 3.2e-05 23.7 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII83672.1 - 0.033 13.0 0.1 0.075 11.8 0.0 1.7 1 1 1 2 2 2 0 Fungal specific transcription factor domain SKN1 PF03935.10 KII83673.1 - 3.7e-186 619.1 0.1 4.4e-186 618.9 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Lyase_1 PF00206.15 KII83674.1 - 2.3e-22 79.5 0.0 3.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KII83674.1 - 4.1e-17 61.9 0.0 1.1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.20 KII83675.1 - 1.8e-69 233.8 0.0 2.6e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII83675.1 - 1.3e-38 132.5 0.0 2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII83675.1 - 1.5e-05 24.1 0.0 2.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII83675.1 - 0.002 17.4 0.1 0.0042 16.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family KA1 PF02149.14 KII83675.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 zf-H2C2 PF09337.5 KII83676.1 - 0.011 15.1 0.3 0.017 14.5 0.2 1.3 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger DUF1610 PF07754.6 KII83676.1 - 0.17 12.0 0.2 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) 3Beta_HSD PF01073.14 KII83677.1 - 3.6e-60 203.0 0.0 4.3e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII83677.1 - 3.2e-36 124.9 0.0 4.2e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII83677.1 - 1.2e-13 51.4 0.2 3e-13 50.1 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII83677.1 - 2.8e-12 46.0 4.2 5.6e-10 38.5 1.3 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KII83677.1 - 1.5e-10 40.4 0.0 2.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KII83677.1 - 4.3e-07 29.1 2.8 1.7e-06 27.1 2.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KII83677.1 - 5.1e-05 23.2 8.3 0.00043 20.2 5.7 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KII83677.1 - 0.00096 18.4 0.8 0.0016 17.7 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KII83677.1 - 0.0015 18.2 7.3 0.063 12.9 5.1 2.7 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 KII83677.1 - 0.021 14.8 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Adaptin_N PF01602.15 KII83680.1 - 1.3e-153 512.1 5.1 1.6e-153 511.8 3.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KII83680.1 - 4e-26 91.9 2.9 8.2e-24 84.4 0.1 3.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KII83680.1 - 3e-18 65.8 3.8 3.1e-09 36.9 0.0 5.4 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.17 KII83680.1 - 2e-10 39.8 9.4 0.00037 20.3 0.0 6.0 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KII83680.1 - 2.1e-07 31.2 8.5 0.0058 17.0 0.0 6.2 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.3 KII83680.1 - 0.00015 21.1 0.4 0.11 11.8 0.0 3.4 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 KII83680.1 - 0.06 13.2 6.7 3.8 7.4 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Glyco_hydro_30 PF02055.11 KII83681.1 - 2.5e-30 105.1 1.1 3.9e-30 104.5 0.8 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KII83681.1 - 0.023 13.6 0.0 5.6 5.7 0.0 2.2 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 KII83682.1 - 3e-27 94.9 0.3 3.9e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 RNA_pol PF00940.14 KII83683.1 - 5.8e-164 545.3 0.0 8.1e-164 544.8 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KII83683.1 - 1.3e-73 248.0 1.5 2.1e-73 247.3 1.1 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal ATP_sub_h PF10775.4 KII83684.1 - 4.7e-24 83.8 1.0 7.1e-24 83.3 0.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h IATP PF04568.7 KII83685.1 - 9.6e-09 35.1 4.0 1.1e-08 35.0 2.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP zf-CpG_bind_C PF12269.3 KII83685.1 - 0.069 12.6 3.1 0.086 12.3 2.1 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Uds1 PF15456.1 KII83685.1 - 0.074 13.0 5.6 0.081 12.9 3.9 1.0 1 0 0 1 1 1 0 Up-regulated During Septation Bap31 PF05529.7 KII83685.1 - 0.11 11.9 4.4 0.11 11.9 3.1 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 KII83685.1 - 0.12 12.4 3.6 0.13 12.3 2.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SpoOE-like PF09388.5 KII83685.1 - 0.2 11.1 1.5 0.34 10.4 1.0 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Mnd1 PF03962.10 KII83685.1 - 0.53 9.9 6.7 0.58 9.7 4.6 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 KII83685.1 - 1.2 8.6 5.1 1.4 8.4 3.2 1.4 1 1 0 1 1 1 0 Septum formation initiator BetaGal_dom3 PF13363.1 KII83690.1 - 0.078 12.3 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 F-box-like PF12937.2 KII83691.1 - 0.052 13.2 0.2 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 F-box-like Abhydrolase_6 PF12697.2 KII83692.1 - 0.003 17.4 0.0 0.0089 15.9 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KII83692.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Aldo_ket_red PF00248.16 KII83693.1 - 1.1e-43 149.0 0.0 1.3e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IncA PF04156.9 KII83696.1 - 0.056 13.0 0.4 0.094 12.2 0.3 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KII83696.1 - 0.14 12.0 5.8 3.8 7.3 1.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.6 KII83696.1 - 0.19 10.1 0.4 0.3 9.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.17 KII83696.1 - 0.23 11.4 1.5 0.4 10.7 1.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KII83696.1 - 0.29 11.0 4.4 0.51 10.2 3.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_N PF10481.4 KII83696.1 - 0.69 9.2 3.5 0.53 9.6 0.5 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF3808 PF10300.4 KII83697.1 - 5.4e-83 279.1 0.0 8.1e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KII83697.1 - 5.5e-06 25.9 3.5 0.00016 21.2 0.3 3.4 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KII83697.1 - 1.3e-05 25.0 0.1 0.0064 16.4 0.0 3.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII83697.1 - 0.00012 22.6 0.4 0.4 11.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII83697.1 - 0.00027 20.5 8.0 0.0037 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII83697.1 - 0.00048 20.5 0.1 0.63 10.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII83697.1 - 0.0034 16.9 0.1 0.013 15.0 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII83697.1 - 0.0044 16.7 0.9 0.046 13.5 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII83697.1 - 0.006 16.8 0.1 0.18 12.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII83697.1 - 0.022 15.2 0.1 4.6 7.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KII83697.1 - 0.094 13.1 7.4 0.12 12.8 0.3 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KII83697.1 - 0.22 11.3 3.2 0.91 9.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 KII83699.1 - 6.8e-40 136.9 0.0 9e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V FHA PF00498.21 KII83700.1 - 3.5e-16 59.0 0.0 7.8e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.7 KII83701.1 - 0.024 14.4 0.5 0.14 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SPX PF03105.14 KII83701.1 - 0.26 11.0 4.9 14 5.3 3.2 2.2 1 1 0 2 2 2 0 SPX domain Baculo_PEP_C PF04513.7 KII83701.1 - 0.34 10.7 3.0 1.7 8.4 1.8 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SMN PF06003.7 KII83701.1 - 0.48 9.4 4.3 0.98 8.4 0.0 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) NPV_P10 PF05531.7 KII83701.1 - 0.99 9.6 3.4 1.9 8.7 0.9 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CDC45 PF02724.9 KII83701.1 - 1 7.2 8.2 1.8 6.4 5.7 1.4 1 0 0 1 1 1 0 CDC45-like protein BMFP PF04380.8 KII83701.1 - 2 8.6 10.0 2.1 8.5 0.7 4.0 3 1 1 4 4 4 0 Membrane fusogenic activity Hex_IIIa PF02455.11 KII83701.1 - 7.4 5.1 7.8 7.4 5.1 4.5 1.6 1 1 0 1 1 1 0 Hexon-associated protein (IIIa) BTB PF00651.26 KII83702.1 - 0.0086 16.0 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain NAD_binding_10 PF13460.1 KII83703.1 - 5.7e-27 94.9 0.4 6.7e-27 94.6 0.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 KII83703.1 - 0.00024 20.9 0.8 0.049 13.4 0.0 2.2 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KII83703.1 - 0.0028 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII83703.1 - 0.02 13.8 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.8 KII83703.1 - 0.07 12.3 0.1 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KII83704.1 - 2.1e-16 60.3 0.1 4.2e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII83704.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII83704.1 - 0.0022 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KII83704.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 KII83705.1 - 3.2e-38 131.3 49.5 1.1e-37 129.6 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII83705.1 - 1.6e-10 40.1 8.1 1.6e-10 40.1 5.6 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter SET PF00856.23 KII83706.1 - 7.9e-09 36.0 0.1 1.5e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 SET domain UBN2_2 PF14227.1 KII83711.1 - 0.005 16.3 0.6 0.0097 15.4 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII83711.1 - 0.072 12.8 1.1 0.13 12.0 0.3 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type SKG6 PF08693.5 KII83713.1 - 0.00029 20.0 0.3 0.00064 18.9 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1282 PF06930.7 KII83713.1 - 0.15 11.7 0.8 0.24 11.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) EST1_DNA_bind PF10373.4 KII83716.1 - 0.047 12.9 0.2 0.077 12.2 0.2 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF3958 PF13125.1 KII83716.1 - 0.047 13.5 0.4 0.091 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) RPW8 PF05659.6 KII83716.1 - 0.072 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Pkinase_Tyr PF07714.12 KII83716.1 - 0.082 11.9 0.0 0.69 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase ADH_zinc_N PF00107.21 KII83718.1 - 1.4e-12 47.3 0.5 2.7e-12 46.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII83718.1 - 6.8e-07 29.0 0.0 3.2e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII83719.1 - 4.5e-16 58.5 0.1 7.7e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII83719.1 - 7.1e-06 25.7 0.1 2e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII83719.1 - 0.00045 21.1 0.1 0.0009 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KII83719.1 - 0.073 12.6 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DivIC PF04977.10 KII83720.1 - 0.00063 19.1 2.8 0.39 10.2 0.5 2.1 2 0 0 2 2 2 2 Septum formation initiator HALZ PF02183.13 KII83720.1 - 0.00086 18.9 0.7 0.62 9.8 0.0 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper Cortex-I_coil PF09304.5 KII83720.1 - 0.003 17.5 2.1 0.0091 16.0 1.6 1.6 1 1 1 2 2 2 1 Cortexillin I, coiled coil DMPK_coil PF08826.5 KII83720.1 - 0.013 15.3 1.6 0.031 14.1 0.9 1.8 1 1 0 1 1 1 0 DMPK coiled coil domain like TSC22 PF01166.13 KII83720.1 - 0.019 14.9 1.2 0.058 13.3 0.1 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family ALIX_LYPXL_bnd PF13949.1 KII83720.1 - 0.024 13.6 0.2 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV ATG16 PF08614.6 KII83720.1 - 0.024 14.4 0.9 0.032 14.0 0.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 KII83720.1 - 0.039 14.2 0.9 0.64 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CCDC155 PF14662.1 KII83720.1 - 0.068 12.7 2.5 0.28 10.7 1.8 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF4140 PF13600.1 KII83720.1 - 0.084 13.3 2.3 6.9 7.1 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.7 KII83720.1 - 0.09 12.5 1.8 0.16 11.6 1.3 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.1 KII83720.1 - 0.1 11.9 2.4 0.22 10.8 1.7 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ADIP PF11559.3 KII83720.1 - 0.12 12.3 3.2 0.42 10.5 0.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 KII83720.1 - 0.17 11.7 3.8 7 6.5 0.0 2.6 2 1 0 2 2 2 0 Basic region leucine zipper MerR-DNA-bind PF09278.6 KII83720.1 - 0.19 12.1 2.9 4.5 7.7 0.7 2.2 2 0 0 2 2 2 0 MerR, DNA binding IFT20 PF14931.1 KII83720.1 - 0.44 10.4 2.9 0.44 10.4 0.4 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Spc24 PF08286.6 KII83720.1 - 0.5 10.0 2.4 10 5.8 0.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.1 KII83720.1 - 1.3 8.9 4.3 15 5.5 3.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TLD PF07534.11 KII83721.1 - 1.2e-30 106.3 0.0 1.8e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 TLD Ferric_reduct PF01794.14 KII83722.1 - 2.1e-17 63.3 8.3 2.1e-17 63.3 5.7 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KII83722.1 - 2.4e-11 43.8 0.0 6.9e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KII83722.1 - 3.8e-09 36.3 0.0 6.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ctr PF04145.10 KII83723.1 - 2.3e-25 89.3 0.2 2.7e-25 89.0 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Romo1 PF10247.4 KII83723.1 - 0.47 10.6 7.1 9.7 6.4 1.9 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DnaJ PF00226.26 KII83724.1 - 1.5e-15 56.6 0.1 2.7e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.8 KII83724.1 - 1.4 8.6 6.9 1.7 8.4 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.26 KII83725.1 - 6.3e-13 48.2 0.3 6.3e-13 48.2 0.2 2.2 2 1 0 2 2 2 1 DnaJ domain T2SF PF00482.18 KII83725.1 - 1.3 8.9 5.0 5.8 6.8 3.8 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Macoilin PF09726.4 KII83725.1 - 4.8 5.3 16.2 8.2 4.5 11.2 1.3 1 0 0 1 1 1 0 Transmembrane protein HAUS6_N PF14661.1 KII83725.1 - 7.7 5.7 15.7 2.3 7.4 8.7 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF2545 PF10810.3 KII83726.1 - 0.028 14.8 1.4 0.061 13.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) Baculo_PEP_C PF04513.7 KII83726.1 - 0.053 13.3 7.6 0.045 13.5 3.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CoatB PF10389.4 KII83726.1 - 7.5 6.5 7.8 40 4.1 0.1 3.2 3 0 0 3 3 3 0 Bacteriophage coat protein B Xan_ur_permease PF00860.15 KII83727.1 - 3.7e-57 193.5 33.9 8.9e-56 189.0 23.5 2.2 1 1 0 1 1 1 1 Permease family DUF3278 PF11683.3 KII83727.1 - 5 7.1 6.1 1.3 9.0 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3278) TauD PF02668.11 KII83728.1 - 8.3e-41 140.3 0.0 1.1e-40 140.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DnaJ PF00226.26 KII83729.1 - 5e-14 51.7 0.0 6.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain O-FucT PF10250.4 KII83730.1 - 1.6e-06 27.4 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase YusW PF14039.1 KII83733.1 - 0.0089 16.2 0.3 0.015 15.5 0.2 1.4 1 0 0 1 1 1 1 YusW-like protein PuR_N PF09182.5 KII83733.1 - 0.21 11.2 0.7 0.71 9.5 0.1 2.0 1 1 1 2 2 2 0 Bacterial purine repressor, N-terminal CAF1A PF12253.3 KII83734.1 - 0.33 11.0 4.9 0.58 10.3 3.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A BTB PF00651.26 KII83735.1 - 0.0024 17.8 0.2 0.01 15.8 0.1 2.0 2 1 0 2 2 2 1 BTB/POZ domain Terpene_synth_C PF03936.11 KII83736.1 - 0.00029 20.1 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ADH_zinc_N PF00107.21 KII83737.1 - 1.7e-11 43.7 0.1 3e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII83737.1 - 1.6e-08 34.2 0.0 4.5e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII83737.1 - 0.029 15.2 0.0 0.058 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1675 PF07897.6 KII83741.1 - 0.89 9.3 5.5 1.3 8.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 KII83741.1 - 9 4.1 7.2 10 3.9 5.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SKG6 PF08693.5 KII83745.1 - 0.0004 19.6 0.2 0.0004 19.6 0.1 3.9 5 0 0 5 5 5 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KII83745.1 - 0.035 13.6 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF966 PF06136.8 KII83745.1 - 0.11 11.9 15.0 0.15 11.4 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S64 PF08192.6 KII83745.1 - 1.2 7.4 16.7 1.4 7.1 11.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.4 KII83745.1 - 7.7 5.2 15.6 11 4.7 10.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain B56 PF01603.15 KII83746.1 - 1.6e-165 550.7 2.1 1.9e-165 550.4 1.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1412 PF07203.6 KII83746.1 - 0.37 10.7 1.5 23 4.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) Ank_2 PF12796.2 KII83747.1 - 1e-14 54.5 3.4 7.6e-11 42.2 0.1 2.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) zf-MYND PF01753.13 KII83747.1 - 3.8e-10 39.4 14.1 6.4e-10 38.7 9.8 1.4 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.1 KII83747.1 - 5.1e-09 36.4 2.2 0.027 15.0 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII83747.1 - 6.8e-08 32.5 6.1 0.00017 21.7 0.3 3.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 KII83747.1 - 4.7e-07 29.3 4.2 0.026 14.3 0.9 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KII83747.1 - 5.9e-05 22.9 0.9 0.19 12.0 0.2 4.2 4 0 0 4 4 4 1 Ankyrin repeat FlhE PF06366.8 KII83748.1 - 0.0092 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Flagellar protein FlhE DUF3815 PF12821.2 KII83749.1 - 0.14 12.1 0.1 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) Vir_act_alpha_C PF10400.4 KII83749.1 - 0.14 12.5 2.5 0.29 11.5 1.7 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term Cep57_CLD_2 PF14197.1 KII83749.1 - 0.25 11.2 4.7 0.47 10.4 3.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 KcnmB2_inactiv PF09303.5 KII83749.1 - 3.1 7.6 5.6 2.4 7.9 0.3 2.6 1 1 1 2 2 2 0 KCNMB2, ball and chain domain Glyco_transf_20 PF00982.16 KII83753.1 - 2.1e-28 99.0 0.5 2.4e-28 98.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 SIP PF04954.8 KII83757.1 - 0.0079 16.5 0.7 0.021 15.1 0.5 1.6 1 0 0 1 1 1 1 Siderophore-interacting protein F-box-like PF12937.2 KII83757.1 - 0.068 12.8 0.3 0.16 11.7 0.2 1.7 1 0 0 1 1 1 0 F-box-like DnaJ PF00226.26 KII83758.1 - 1.1e-14 53.9 0.0 1.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain 4HBT_2 PF13279.1 KII83759.1 - 1.5e-07 31.9 0.0 2.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily ABC_tran PF00005.22 KII83760.1 - 1.2e-48 164.8 0.0 4.9e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII83760.1 - 2.8e-44 151.5 24.6 9.3e-27 94.1 3.8 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KII83760.1 - 3.9e-09 36.9 0.0 0.2 11.5 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KII83760.1 - 4.2e-08 32.8 0.1 0.00031 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KII83760.1 - 7.5e-08 31.5 0.1 0.0033 16.3 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 KII83760.1 - 5.7e-06 25.7 0.0 0.18 10.9 0.0 4.1 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KII83760.1 - 2.8e-05 23.5 0.2 0.27 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KII83760.1 - 0.0001 22.7 0.1 0.024 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII83760.1 - 0.00012 22.1 0.4 0.57 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KII83760.1 - 0.00012 21.6 0.1 0.093 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 KII83760.1 - 0.001 18.9 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KII83760.1 - 0.0024 17.5 0.7 1.2 8.9 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 KII83760.1 - 0.0036 17.0 0.2 0.77 9.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KII83760.1 - 0.015 15.4 0.1 25 5.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KII83760.1 - 0.015 16.0 0.0 4.4 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KII83760.1 - 0.017 14.6 0.3 0.75 9.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KII83760.1 - 0.036 13.8 0.1 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 KII83760.1 - 0.038 13.0 0.2 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 KII83760.1 - 0.052 13.5 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KII83760.1 - 0.054 13.7 0.1 18 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF3018 PF11455.3 KII83760.1 - 0.2 11.6 0.3 0.46 10.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Arch_ATPase PF01637.13 KII83760.1 - 0.22 11.2 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 KII83760.1 - 0.29 11.6 0.4 22 5.5 0.1 2.4 2 0 0 2 2 2 0 Miro-like protein MFS_1 PF07690.11 KII83762.1 - 4.9e-43 147.1 66.0 4e-32 111.3 21.7 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2976 PF11190.3 KII83762.1 - 0.012 15.1 0.2 0.012 15.1 0.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2976) DUF2663 PF10864.3 KII83762.1 - 0.049 13.8 0.7 0.31 11.2 0.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) O-FucT PF10250.4 KII83763.1 - 0.2 10.7 0.0 0.61 9.1 0.0 1.7 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase TPR_11 PF13414.1 KII83764.1 - 1.4e-20 72.6 18.2 0.00018 21.1 0.0 7.1 5 1 3 8 8 8 7 TPR repeat TPR_19 PF14559.1 KII83764.1 - 3.2e-12 46.6 14.5 0.0017 18.6 0.0 7.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII83764.1 - 7.1e-12 44.2 19.1 0.12 12.3 0.1 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII83764.1 - 1.7e-11 44.4 35.5 0.00047 20.7 0.0 8.8 9 2 4 13 13 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 KII83764.1 - 5.9e-11 42.0 0.5 0.7 10.4 0.0 7.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII83764.1 - 7.1e-10 38.6 30.3 6.4e-05 22.8 0.2 8.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII83764.1 - 7.7e-08 32.3 26.4 0.12 13.1 0.1 10.8 10 2 3 13 13 11 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII83764.1 - 9.1e-07 28.2 8.9 0.23 11.3 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII83764.1 - 2.1e-06 27.4 4.2 3.8 7.9 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII83764.1 - 6.4e-06 25.5 8.4 2 8.4 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KII83764.1 - 0.00014 22.1 1.0 0.84 9.8 0.0 3.4 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.1 KII83764.1 - 0.00016 21.7 11.9 0.024 14.7 0.2 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KII83764.1 - 0.00019 21.5 13.0 0.005 16.9 0.1 5.4 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KII83764.1 - 0.0025 17.6 16.8 0.017 14.9 0.2 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII83764.1 - 0.0029 17.1 15.1 0.17 11.5 0.0 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat DUF2225 PF09986.4 KII83764.1 - 0.0055 16.1 0.3 0.24 10.8 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Apc5 PF12862.2 KII83764.1 - 0.48 10.3 3.8 12 5.8 0.0 4.2 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 SNAP PF14938.1 KII83764.1 - 0.77 8.8 6.9 0.16 11.0 0.2 2.8 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP TylF PF05711.6 KII83766.1 - 0.053 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) EndoU_bacteria PF14436.1 KII83767.1 - 0.034 13.9 0.1 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease Chitin_bind_4 PF00379.18 KII83767.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Insect cuticle protein p450 PF00067.17 KII83768.1 - 6.5e-65 219.4 0.0 3.6e-52 177.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 COMP PF11598.3 KII83768.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Gti1_Pac2 PF09729.4 KII83771.1 - 1.7e-26 93.1 0.4 2.1e-22 79.7 0.0 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family Pkinase_Tyr PF07714.12 KII83772.1 - 1.1e-50 172.1 0.0 1.9e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII83772.1 - 6.1e-46 156.6 0.0 1.7e-45 155.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KII83772.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII83772.1 - 0.0017 17.7 0.3 0.0034 16.7 0.0 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KII83772.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 KII83773.1 - 2.3e-53 180.8 0.0 2.8e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CbiG_N PF11760.3 KII83773.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Methyltransf_22 PF13383.1 KII83775.1 - 9.6e-31 107.1 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KII83775.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.1 KII83776.1 - 8.4e-31 107.3 0.0 1e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KII83776.1 - 5.5e-07 29.6 0.0 8.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain MARVEL PF01284.18 KII83777.1 - 0.0047 16.7 7.7 0.01 15.6 5.4 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF2583 PF10762.4 KII83777.1 - 2.1 8.5 4.6 1.2 9.2 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) F-box-like PF12937.2 KII83778.1 - 0.00035 20.2 1.5 0.0017 18.0 0.2 2.7 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KII83778.1 - 0.69 9.7 2.4 58 3.5 0.0 4.1 5 0 0 5 5 5 0 Leucine rich repeat AA_permease PF00324.16 KII83780.1 - 6.2e-120 400.7 37.0 7.4e-120 400.5 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII83780.1 - 1.3e-31 109.6 42.7 1.6e-31 109.3 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease Cation_ATPase_C PF00689.16 KII83780.1 - 8.5 5.8 18.6 0.031 13.8 3.5 2.5 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Abhydrolase_6 PF12697.2 KII83781.1 - 1.7e-24 86.9 1.6 2.1e-24 86.6 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII83781.1 - 0.00081 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII83781.1 - 0.014 14.9 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ndr PF03096.9 KII83781.1 - 0.056 11.9 0.0 0.16 10.4 0.0 1.7 2 0 0 2 2 2 0 Ndr family DGF-1_C PF11040.3 KII83782.1 - 8.7e-05 22.3 0.5 0.00018 21.3 0.4 1.5 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF4588 PF15251.1 KII83782.1 - 0.0014 18.7 5.0 0.0059 16.6 3.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CDV3 PF15359.1 KII83782.1 - 0.0044 17.1 0.6 0.0067 16.4 0.4 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 DUF2890 PF11081.3 KII83782.1 - 0.17 11.9 2.6 0.28 11.2 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ABC_tran PF00005.22 KII83783.1 - 3.4e-51 173.1 0.0 1.5e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII83783.1 - 7.8e-50 169.8 25.5 7.4e-24 84.6 1.3 3.5 3 1 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KII83783.1 - 3.9e-10 40.1 0.0 0.3 10.9 0.0 4.4 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KII83783.1 - 2.9e-07 29.9 0.6 0.0045 16.2 0.1 3.9 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KII83783.1 - 4.1e-07 29.1 0.1 0.0047 15.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 KII83783.1 - 3.1e-06 26.7 0.0 0.031 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII83783.1 - 3.8e-06 26.3 0.3 0.08 12.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KII83783.1 - 7.8e-05 23.0 4.5 0.0021 18.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KII83783.1 - 0.00011 22.2 1.3 0.36 10.7 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 KII83783.1 - 0.00086 19.4 0.1 6.6 6.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KII83783.1 - 0.0035 17.1 0.1 0.0097 15.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 KII83783.1 - 0.0052 16.6 0.3 1.1 9.1 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KII83783.1 - 0.008 16.9 0.2 8.3 7.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KII83783.1 - 0.011 15.1 0.0 1 8.8 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KII83783.1 - 0.013 15.8 0.1 9.2 6.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KII83783.1 - 0.016 14.9 0.0 8.5 6.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KII83783.1 - 0.021 14.3 0.2 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KII83783.1 - 0.034 14.1 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RseC_MucC PF04246.7 KII83783.1 - 0.063 12.8 0.0 0.063 12.8 0.0 2.5 3 0 0 3 3 1 0 Positive regulator of sigma(E), RseC/MucC Arch_ATPase PF01637.13 KII83783.1 - 0.064 12.9 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 KII83783.1 - 0.089 12.6 0.1 18 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KII83783.1 - 0.1 12.3 3.8 0.92 9.3 0.0 3.4 4 0 0 4 4 2 0 Part of AAA domain cobW PF02492.14 KII83783.1 - 0.19 11.1 0.8 4 6.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KII83783.1 - 0.27 10.8 1.3 6.5 6.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 KII83783.1 - 0.82 9.4 3.9 5.4 6.8 0.0 2.9 3 0 0 3 3 2 0 Dynamin family HNH_2 PF13391.1 KII83784.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Metallophos PF00149.23 KII83786.1 - 1.5e-40 138.7 0.1 1.9e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1620 PF07774.8 KII83787.1 - 4.9e-71 238.4 0.2 7.6e-71 237.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KII83787.1 - 1.1e-13 51.2 5.3 1e-07 31.6 0.8 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 KII83787.1 - 2.2e-12 45.8 0.6 0.0035 16.7 0.0 5.5 5 0 0 5 5 5 3 PQQ enzyme repeat ApoO PF09769.4 KII83788.1 - 3.9e-31 107.8 0.3 7e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein O Phasin PF05597.6 KII83788.1 - 0.018 14.8 3.5 2 8.1 0.7 2.9 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 KII83788.1 - 1.5 9.2 6.1 7.1 7.1 1.3 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) SNF2_N PF00176.18 KII83790.1 - 1.5e-58 197.9 0.0 2.5e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII83790.1 - 6.6e-15 54.7 0.0 1.8e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.24 KII83790.1 - 2.3e-06 27.1 20.0 2.9e-05 23.6 2.5 3.3 3 0 0 3 3 3 2 PHD-finger DEAD PF00270.24 KII83790.1 - 5.5e-05 22.7 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase C1_1 PF00130.17 KII83790.1 - 0.0012 18.4 1.9 0.0012 18.4 1.3 3.0 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 KII83790.1 - 1.2 9.0 16.8 1.7 8.5 3.4 2.7 2 0 0 2 2 2 0 Ring finger domain NOA36 PF06524.7 KII83790.1 - 5.7 6.1 14.4 0.47 9.6 5.0 2.0 1 1 1 2 2 2 0 NOA36 protein Peptidase_M36 PF02128.10 KII83791.1 - 1.8e-111 372.6 10.2 2.3e-111 372.3 7.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) PepSY PF03413.14 KII83791.1 - 0.00019 22.0 0.2 0.00046 20.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Peptidase_M4_C PF02868.10 KII83791.1 - 0.0086 15.8 0.1 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 KII83791.1 - 0.037 14.0 0.0 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Peptidase MA superfamily FTP PF07504.8 KII83791.1 - 0.092 12.2 0.3 0.092 12.2 0.2 2.1 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif Tubulin_3 PF14881.1 KII83792.1 - 7.3e-34 116.7 0.2 1.5e-33 115.7 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KII83792.1 - 4.5e-33 113.7 0.0 1.3e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KII83792.1 - 2e-05 24.5 0.0 0.00057 19.7 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Sec66 PF09802.4 KII83792.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 RCR PF12273.3 KII83793.1 - 1.4 9.4 6.2 0.18 12.3 0.5 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Glyco_transf_20 PF00982.16 KII83794.1 - 1.8e-142 475.2 0.0 2.3e-142 474.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KII83794.1 - 4.9e-26 91.0 0.0 2.8e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase AA_permease PF00324.16 KII83798.1 - 6.1e-122 407.3 33.8 7.6e-122 407.0 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII83798.1 - 9.6e-32 110.0 38.7 1.3e-31 109.6 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1705 PF08019.7 KII83799.1 - 0.07 12.6 0.5 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Herpes_gE PF02480.11 KII83799.1 - 0.13 10.5 0.1 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ribosomal_S19 PF00203.16 KII83800.1 - 4e-21 74.3 0.0 5.4e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Pkinase PF00069.20 KII83801.1 - 3.9e-74 249.0 0.3 3.9e-74 249.0 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII83801.1 - 7.7e-53 179.2 3.7 9.3e-53 178.9 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KII83801.1 - 2.8e-22 78.9 0.0 7.3e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain DUF1777 PF08648.7 KII83801.1 - 7.6e-08 32.2 10.5 1.6e-07 31.2 7.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Kinase-like PF14531.1 KII83801.1 - 1.3e-06 27.5 0.0 3.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KII83801.1 - 0.00032 20.8 0.1 0.00069 19.7 0.1 1.6 1 0 0 1 1 1 1 PH domain PRP38_assoc PF12871.2 KII83801.1 - 0.00048 20.5 24.0 0.0011 19.3 16.7 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term APH PF01636.18 KII83801.1 - 0.0032 17.2 0.0 0.0032 17.2 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF2363 PF10155.4 KII83802.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) GATase_6 PF13522.1 KII83803.1 - 2.2e-14 53.5 0.0 4.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KII83803.1 - 1.5e-11 43.4 0.1 1.1e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 KII83803.1 - 0.0032 17.1 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KII83803.1 - 0.004 15.9 0.5 0.0076 14.9 0.3 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II DUF3172 PF11371.3 KII83803.1 - 0.041 13.3 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) CobA_CobO_BtuR PF02572.10 KII83806.1 - 0.12 11.9 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Trypan_PARP PF05887.6 KII83806.1 - 0.18 11.6 9.2 0.091 12.5 3.1 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_3 PF07859.8 KII83807.1 - 4.9e-19 68.7 0.0 6.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KII83807.1 - 1.6e-07 30.3 0.0 2.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF3593 PF12159.3 KII83808.1 - 0.042 13.6 0.5 0.042 13.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) She9_MDM33 PF05546.6 KII83808.1 - 0.11 12.0 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family STE3 PF02076.10 KII83813.1 - 3.8e-104 347.7 16.8 4.4e-104 347.5 11.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor Dispanin PF04505.7 KII83813.1 - 0.043 13.3 0.4 0.043 13.3 0.2 3.4 3 1 1 4 4 4 0 Interferon-induced transmembrane protein DUF898 PF05987.8 KII83813.1 - 0.074 11.9 9.8 0.015 14.1 3.8 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Pheromone PF08015.6 KII83814.1 - 8.6e-07 29.6 3.6 1.7e-06 28.7 2.5 1.5 1 1 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.10 KII83815.1 - 6.7e-107 356.7 21.1 7.7e-107 356.5 14.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.6 KII83817.1 - 0.0015 19.2 2.0 0.0015 19.2 1.4 2.3 2 1 0 2 2 2 1 Fungal mating-type pheromone Pheromone PF08015.6 KII83818.1 - 7.7e-05 23.4 3.3 0.00014 22.6 2.3 1.4 1 1 0 1 1 1 1 Fungal mating-type pheromone Alpha_GJ PF03229.8 KII83818.1 - 0.12 12.7 0.3 0.13 12.5 0.2 1.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J MMPL PF03176.10 KII83819.1 - 0.025 13.3 0.8 0.027 13.1 0.6 1.0 1 0 0 1 1 1 0 MMPL family S1FA PF04689.8 KII83819.1 - 0.3 10.9 1.7 0.34 10.8 0.8 1.4 1 1 0 1 1 1 0 DNA binding protein S1FA STE3 PF02076.10 KII83820.1 - 1.5e-105 352.3 16.6 1.8e-105 352.1 11.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.6 KII83821.1 - 1e-08 35.8 0.7 1.3e-08 35.5 0.5 1.1 1 0 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.10 KII83822.1 - 1.8e-97 325.8 17.2 2.2e-97 325.5 11.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF443 PF04276.7 KII83827.1 - 3.2 7.1 6.8 0.15 11.4 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF443) TraP PF07296.6 KII83829.1 - 0.00064 18.7 1.4 0.001 18.0 1.0 1.3 1 0 0 1 1 1 1 TraP protein Lenti_VIF_2 PF07401.7 KII83831.1 - 0.0025 16.9 2.4 0.068 12.2 0.7 2.6 1 1 1 2 2 2 1 Bovine Lentivirus VIF protein MNSV_P7B PF06692.6 KII83835.1 - 0.056 13.2 0.2 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein BolA PF01722.13 KII83836.1 - 1.7e-20 72.7 0.0 2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DUF373 PF04123.8 KII83837.1 - 2.1 7.3 6.5 3.1 6.7 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Caveolin PF01146.12 KII83838.1 - 0.52 9.8 7.1 2.4 7.7 0.3 2.4 2 0 0 2 2 2 0 Caveolin Syndecan PF01034.15 KII83840.1 - 0.37 10.4 0.0 0.37 10.4 0.0 3.7 5 0 0 5 5 5 0 Syndecan domain DUF89 PF01937.14 KII83842.1 - 4.7e-71 239.4 0.0 5.8e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sulf_transp PF04143.9 KII83843.1 - 2.5 8.1 7.0 0.73 9.9 0.4 2.9 3 0 0 3 3 3 0 Sulphur transport Tetraspannin PF00335.15 KII83846.1 - 8.7 5.5 29.1 4.2 6.5 15.4 2.8 2 1 0 2 2 2 0 Tetraspanin family 4HBT PF03061.17 KII83847.1 - 5.9e-08 32.7 0.0 0.00039 20.4 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily UPF0182 PF03699.8 KII83848.1 - 0.029 12.3 8.3 0.04 11.8 5.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Amino_oxidase PF01593.19 KII83849.1 - 6.9e-64 216.5 0.2 1.2e-49 169.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII83849.1 - 4.4e-11 42.6 0.2 1.2e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII83849.1 - 2.5e-05 23.3 0.0 0.0022 16.9 0.4 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII83849.1 - 6.2e-05 22.2 0.2 9.6e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KII83849.1 - 0.0013 18.8 0.8 0.014 15.4 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII83849.1 - 0.0021 17.2 0.3 0.0028 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII83849.1 - 0.0031 16.4 0.4 0.0054 15.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain B12-binding PF02310.14 KII83849.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain GIDA PF01134.17 KII83849.1 - 0.03 13.2 0.1 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KII83849.1 - 0.042 13.9 0.1 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 KII83849.1 - 0.055 13.0 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KII83849.1 - 0.056 13.8 2.4 0.16 12.3 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII83849.1 - 0.068 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII83849.1 - 0.1 11.0 0.3 0.15 10.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KII83849.1 - 0.12 12.1 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Transp_cyt_pur PF02133.10 KII83850.1 - 2.3e-111 372.5 38.1 2.7e-111 372.2 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2374 PF09574.5 KII83850.1 - 0.061 12.9 2.9 1.3 8.7 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Pkinase PF00069.20 KII83851.1 - 1.8e-51 174.7 0.0 2.7e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII83851.1 - 2.3e-47 161.2 0.0 3.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KII83851.1 - 4.1e-07 29.6 0.9 7.8e-07 28.7 0.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 KII83851.1 - 0.0032 17.2 0.2 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KII83851.1 - 0.0037 16.3 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII83851.1 - 0.02 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PHD PF00628.24 KII83851.1 - 0.039 13.6 3.8 0.078 12.6 2.6 1.5 1 0 0 1 1 1 0 PHD-finger Seadorna_VP7 PF07387.6 KII83851.1 - 0.079 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Prok-RING_1 PF14446.1 KII83851.1 - 1.5 8.5 5.0 3.4 7.4 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Pkinase_Tyr PF07714.12 KII83852.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase XPG_I PF00867.13 KII83853.1 - 1.7e-19 69.6 0.0 4.9e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KII83853.1 - 0.0002 21.5 0.0 0.00064 19.9 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain MbeB_N PF04837.7 KII83853.1 - 0.051 13.6 0.5 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Menin PF05053.8 KII83853.1 - 0.74 7.9 3.4 1.2 7.2 2.4 1.2 1 0 0 1 1 1 0 Menin Rap_GAP PF02145.10 KII83854.1 - 2.6e-43 147.5 0.0 4.4e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KII83854.1 - 8.6e-28 97.4 0.2 4.2e-26 91.8 0.1 2.2 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.3 KII83854.1 - 0.012 14.1 0.1 0.067 11.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) CENP-X PF09415.5 KII83854.1 - 0.14 11.9 0.5 0.39 10.5 0.4 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X VHS PF00790.14 KII83855.1 - 4.9e-13 48.9 0.0 8.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KII83855.1 - 1.3e-06 28.2 0.0 5.3e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 GAT domain MIP-T3 PF10243.4 KII83855.1 - 0.027 12.9 22.5 0.058 11.8 15.6 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_3 PF00933.16 KII83856.1 - 1.1e-62 211.7 0.0 2.5e-62 210.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain RRM_1 PF00076.17 KII83858.1 - 2.8e-37 126.1 0.1 1.1e-17 63.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII83858.1 - 1.2e-31 108.5 0.0 2.1e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII83858.1 - 2.8e-13 49.4 0.0 3.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KII83858.1 - 0.0018 17.9 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KII83858.1 - 0.003 17.0 0.1 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_3 PF08777.6 KII83858.1 - 0.033 14.0 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif COG7 PF10191.4 KII83859.1 - 3e-82 276.7 2.9 2.3e-46 158.1 2.9 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) DUF2450 PF10475.4 KII83859.1 - 0.1 11.4 0.5 0.28 10.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) RFPL3_antisense PF10489.4 KII83860.1 - 0.038 13.7 1.3 0.048 13.4 0.9 1.3 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense Gag_p12 PF01141.13 KII83860.1 - 0.62 10.2 4.9 0.35 11.0 1.9 1.6 1 1 1 2 2 2 0 Gag polyprotein, inner coat protein p12 Nrf1_activ_bdg PF10492.4 KII83860.1 - 1.8 9.0 4.7 2.4 8.6 3.3 1.2 1 0 0 1 1 1 0 Nrf1 activator activation site binding domain Bim_N PF06773.6 KII83860.1 - 3.1 7.6 8.4 9.3 6.0 1.7 2.8 2 1 0 2 2 2 0 Bim protein N-terminus TniB PF05621.6 KII83862.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein MIP-T3 PF10243.4 KII83863.1 - 7.9 4.8 20.8 9.5 4.5 14.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mpv17_PMP22 PF04117.7 KII83865.1 - 2.4e-22 78.3 0.8 4.5e-22 77.4 0.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2296 PF10058.4 KII83866.1 - 1.4e-16 59.9 0.7 2.2e-16 59.3 0.5 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF1610 PF07754.6 KII83866.1 - 0.0063 16.6 0.2 0.016 15.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.2 KII83866.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain LRR_4 PF12799.2 KII83868.1 - 0.027 14.0 0.0 39 4.0 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Asp PF00026.18 KII83870.1 - 1.7e-06 27.4 0.8 6.4e-06 25.6 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic aspartyl protease UCH PF00443.24 KII83872.1 - 1.4e-43 149.0 0.0 1.9e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KII83872.1 - 2e-25 88.6 11.3 3.1e-20 72.0 0.5 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KII83872.1 - 2.7e-22 77.9 0.1 2.5e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KII83872.1 - 8.4e-15 54.9 0.0 6.1e-13 48.8 0.0 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Stc1 PF12898.2 KII83872.1 - 0.02 14.9 0.5 0.02 14.9 0.3 3.7 6 0 0 6 6 6 0 Stc1 domain zf-MYND PF01753.13 KII83873.1 - 2.2e-07 30.6 15.7 2.2e-07 30.6 10.9 4.4 4 1 0 4 4 4 3 MYND finger F-box PF00646.28 KII83875.1 - 0.002 17.7 0.8 0.021 14.4 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII83875.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like UPF0016 PF01169.14 KII83877.1 - 3.6e-45 152.0 18.8 8.1e-23 80.3 3.9 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 LysE PF01810.13 KII83877.1 - 0.0034 16.6 8.6 0.029 13.6 0.4 2.5 2 1 0 2 2 2 2 LysE type translocator CitMHS PF03600.11 KII83877.1 - 0.015 13.8 7.8 0.14 10.6 1.2 2.3 2 0 0 2 2 2 0 Citrate transporter TerC PF03741.11 KII83877.1 - 0.02 14.3 0.1 0.02 14.3 0.1 2.4 2 1 0 2 2 2 0 Integral membrane protein TerC family TauE PF01925.14 KII83877.1 - 1.4 8.3 16.2 18 4.7 11.3 2.0 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Aldedh PF00171.17 KII83878.1 - 8.7e-187 621.0 0.0 9.9e-187 620.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII83878.1 - 1.9e-05 23.6 0.1 9.4e-05 21.2 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KII83878.1 - 0.12 11.6 0.0 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Peptidase_C54 PF03416.14 KII83879.1 - 2.4e-85 286.0 0.0 8.8e-85 284.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C54 Ras PF00071.17 KII83882.1 - 6.9e-39 132.8 0.0 6.1e-37 126.5 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KII83882.1 - 2.5e-16 60.2 0.0 4.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII83882.1 - 7.4e-07 28.5 0.0 1.7e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII83882.1 - 0.0011 18.4 0.0 0.0086 15.5 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KII83882.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KII83882.1 - 0.0026 16.9 0.0 0.0057 15.8 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KII83882.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KII83882.1 - 0.065 12.8 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KII83882.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 LSM PF01423.17 KII83883.1 - 4.7e-16 58.1 0.1 5.4e-16 57.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KII83883.1 - 4.1e-06 26.6 0.1 5.1e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DEAD PF00270.24 KII83884.1 - 4e-18 65.4 0.0 3.7e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KII83884.1 - 8.1e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII83884.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_6 PF12697.2 KII83885.1 - 1.4e-29 103.6 0.2 1.6e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII83885.1 - 3.5e-10 39.7 0.0 1.3e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII83885.1 - 3.1e-09 36.7 0.0 1.3e-07 31.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KII83885.1 - 2.2e-05 24.1 0.0 0.003 17.1 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase DUF915 PF06028.6 KII83885.1 - 0.0096 15.0 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 KII83885.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF2834 PF11196.3 KII83887.1 - 0.00073 19.6 18.0 0.0029 17.7 1.3 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF2834) DUF3112 PF11309.3 KII83887.1 - 0.043 13.6 4.2 0.049 13.4 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) F-box PF00646.28 KII83891.1 - 0.0067 16.0 0.5 0.0067 16.0 0.3 1.8 2 0 0 2 2 2 1 F-box domain Haem_bd PF14376.1 KII83892.1 - 0.00025 20.7 0.6 0.00025 20.7 0.4 1.8 2 0 0 2 2 2 1 Haem-binding domain F-box PF00646.28 KII83892.1 - 0.0016 18.0 0.1 0.0034 16.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain Cytochrome_CBB3 PF13442.1 KII83892.1 - 0.15 12.2 2.5 0.53 10.4 1.7 2.0 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Phage_holin_1 PF04531.8 KII83895.1 - 0.092 12.8 4.6 0.26 11.3 0.5 2.8 2 1 0 2 2 2 0 Bacteriophage holin TauD PF02668.11 KII83896.1 - 1.8e-54 185.1 0.8 2.1e-54 184.8 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KII83896.1 - 0.00037 20.9 0.1 0.071 13.6 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily NAP PF00956.13 KII83897.1 - 4.3e-81 271.6 4.1 4.3e-81 271.6 2.8 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HSP70 PF00012.15 KII83898.1 - 5.5e-65 219.4 5.0 1.4e-45 155.3 0.0 3.3 2 2 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 KII83898.1 - 1.6e-10 40.1 0.0 5.4e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein zf-CCHC PF00098.18 KII83899.1 - 2.3e-05 24.0 1.9 2.3e-05 24.0 1.3 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 KII83899.1 - 0.016 14.9 0.4 0.032 13.9 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KII83899.1 - 0.02 14.3 2.7 0.045 13.2 1.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Effector_1 PF04518.7 KII83900.1 - 0.047 12.6 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Metal_resist PF13801.1 KII83900.1 - 0.27 11.2 4.8 1.6 8.7 3.3 2.0 1 1 0 1 1 1 0 Heavy-metal resistance DEAD PF00270.24 KII83903.1 - 6.5e-13 48.5 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII83903.1 - 8.7e-09 35.1 1.9 9e-09 35.0 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII83903.1 - 0.00029 20.7 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Epimerase PF01370.16 KII83904.1 - 1.3e-18 67.3 0.0 1.7e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII83904.1 - 1.7e-12 46.6 0.1 2.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KII83904.1 - 1.2e-09 37.5 0.7 2.2e-08 33.3 0.5 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KII83904.1 - 3e-09 37.1 0.9 6.4e-09 36.0 0.6 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII83904.1 - 3.8e-07 29.5 0.2 2.2e-06 27.1 0.5 1.9 3 0 0 3 3 3 1 NmrA-like family Polysacc_synt_2 PF02719.10 KII83904.1 - 5.6e-07 28.7 0.0 8.2e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KII83904.1 - 1.3e-06 28.4 2.3 3.9e-06 26.8 1.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII83904.1 - 0.00055 19.6 3.1 0.0024 17.5 2.2 1.9 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KII83904.1 - 0.024 13.5 0.2 0.4 9.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.16 KII83905.1 - 5e-14 52.3 2.7 1.6e-06 27.7 0.1 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII83905.1 - 2.8e-08 33.3 4.3 0.00012 21.3 0.2 2.4 2 1 1 3 3 3 2 NmrA-like family NAD_binding_10 PF13460.1 KII83905.1 - 1.2e-07 31.9 3.0 0.00018 21.5 0.1 2.7 2 1 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 KII83905.1 - 2.4e-06 27.5 2.5 0.032 14.1 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase 3Beta_HSD PF01073.14 KII83905.1 - 7.1e-06 24.9 2.8 0.074 11.7 0.5 2.9 2 1 1 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KII83905.1 - 7.3e-05 21.8 0.3 0.055 12.3 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.5 KII83905.1 - 0.00029 20.5 3.1 0.28 10.8 0.5 2.4 2 1 0 2 2 2 2 KR domain NAD_binding_4 PF07993.7 KII83905.1 - 0.0004 19.3 5.2 0.21 10.5 0.2 2.9 3 0 0 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.12 KII83905.1 - 0.00045 19.1 0.3 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain DapB_N PF01113.15 KII83905.1 - 0.004 17.0 0.2 3 7.7 0.0 2.3 2 0 0 2 2 2 2 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 KII83905.1 - 0.0055 16.5 0.7 0.26 11.1 0.1 2.6 1 1 2 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII83905.1 - 0.0065 15.6 0.3 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KII83905.1 - 0.016 15.6 0.1 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF39 PF01837.11 KII83905.1 - 0.04 12.5 1.0 0.31 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF39 NAD_binding_2 PF03446.10 KII83905.1 - 0.042 13.6 0.0 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KII83905.1 - 0.075 12.6 0.4 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KII83905.1 - 0.092 13.0 2.1 11 6.3 0.1 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ThiF PF00899.16 KII83905.1 - 0.11 12.3 0.9 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 ThiF family Phage_pRha PF09669.5 KII83905.1 - 0.14 12.5 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) DUF4085 PF13315.1 KII83906.1 - 0.15 11.4 0.3 0.26 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) zf-CCHC PF00098.18 KII83908.1 - 0.95 9.5 3.5 1.8 8.6 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.17 KII83909.1 - 3.1e-69 233.7 0.0 3.9e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.19 KII83910.1 - 4.7e-70 235.0 50.8 1.9e-38 131.7 14.0 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KII83910.1 - 7.9e-38 129.8 0.0 1.2e-18 67.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KII83910.1 - 8.7e-26 89.5 5.7 2.6e-20 72.0 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter AAA_25 PF13481.1 KII83910.1 - 2.6e-09 36.7 0.1 0.0002 20.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain ABC_trans_N PF14510.1 KII83910.1 - 7.1e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 KII83910.1 - 1.7e-05 24.9 0.2 0.12 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KII83910.1 - 3.9e-05 22.8 0.0 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KII83910.1 - 5.8e-05 22.6 0.0 0.0025 17.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 KII83910.1 - 6.1e-05 22.2 15.3 6.1e-05 22.2 10.6 3.7 2 2 1 3 3 3 1 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 KII83910.1 - 9.4e-05 21.9 0.1 0.078 12.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 KII83910.1 - 0.00038 20.4 0.5 0.2 11.6 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KII83910.1 - 0.00042 19.8 0.2 3.7 6.8 0.1 3.6 4 0 0 4 4 4 1 AAA-like domain AAA_29 PF13555.1 KII83910.1 - 0.00043 19.7 0.7 0.13 11.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 KII83910.1 - 0.0005 19.0 0.0 0.26 10.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 KII83910.1 - 0.00073 19.4 0.3 0.79 9.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KII83910.1 - 0.0011 19.2 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KII83910.1 - 0.0013 18.4 0.2 0.2 11.3 0.2 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KII83910.1 - 0.0027 17.3 0.3 0.17 11.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KII83910.1 - 0.0029 17.3 0.7 1.2 8.9 0.5 2.7 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 KII83910.1 - 0.0048 16.8 0.1 0.89 9.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 KII83910.1 - 0.0075 15.5 0.2 0.12 11.5 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KII83910.1 - 0.0091 16.8 0.0 1.6 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KII83910.1 - 0.018 15.0 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KII83910.1 - 0.033 13.7 0.5 5.1 6.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KII83910.1 - 0.038 14.3 0.2 0.078 13.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII83910.1 - 0.063 12.9 0.0 17 4.9 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 KII83910.1 - 0.09 12.9 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 KII83910.1 - 0.14 11.6 0.7 15 4.9 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Miro PF08477.8 KII83910.1 - 0.19 12.2 0.0 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 KII83910.1 - 0.24 10.8 0.2 1.5 8.2 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KII83910.1 - 0.34 10.7 0.7 1.3 8.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Septin PF00735.13 KII83910.1 - 0.42 9.5 0.2 21 4.0 0.1 2.3 2 0 0 2 2 2 0 Septin p450 PF00067.17 KII83911.1 - 9e-76 255.2 0.0 1.1e-75 254.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxysterol_BP PF01237.13 KII83915.1 - 7.8e-120 399.5 0.0 1.4e-119 398.7 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 KII83915.1 - 2.3e-15 56.2 0.6 1.5e-07 31.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KII83915.1 - 7.8e-14 51.7 0.1 4.7e-10 39.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII83915.1 - 8.6e-14 50.5 2.1 0.00025 20.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KII83915.1 - 3.1e-11 42.3 0.5 0.0014 18.6 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KII83915.1 - 2.9e-09 37.1 1.3 9.4e-06 26.0 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 KII83915.1 - 4.7e-08 33.1 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KII83915.1 - 3.9e-05 23.6 0.8 0.00012 22.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain p450 PF00067.17 KII83916.1 - 9e-61 205.7 0.0 1e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 KII83917.1 - 1.9e-16 59.7 0.0 2.6e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KII83917.1 - 0.066 12.4 0.0 0.22 10.7 0.0 1.9 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain Epimerase PF01370.16 KII83918.1 - 4.7e-18 65.4 0.1 1e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII83918.1 - 3.5e-11 42.3 0.0 4.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII83918.1 - 2.8e-10 40.4 0.6 5.5e-10 39.5 0.4 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII83918.1 - 4.7e-10 38.8 1.3 4.6e-09 35.5 0.9 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII83918.1 - 1.8e-07 30.6 0.5 8.5e-07 28.4 0.8 1.8 3 0 0 3 3 3 1 NmrA-like family adh_short PF00106.20 KII83918.1 - 2.4e-07 30.8 2.3 9.6e-07 28.8 1.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KII83918.1 - 2e-06 26.9 0.0 2.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KII83918.1 - 6.9e-05 22.5 2.9 0.00031 20.4 2.0 1.9 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KII83918.1 - 0.038 12.8 0.3 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain F420_oxidored PF03807.12 KII83918.1 - 0.075 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LSM PF01423.17 KII83919.1 - 3e-08 33.0 0.0 3.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4444 PF14563.1 KII83919.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) SM-ATX PF14438.1 KII83919.1 - 0.025 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF2422 PF10337.4 KII83920.1 - 8.3e-64 216.0 12.4 2.9e-63 214.2 6.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KII83920.1 - 7.2e-57 192.6 0.1 1.2e-56 191.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KII83920.1 - 2.8e-09 36.9 9.4 2.8e-09 36.9 6.5 3.8 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ADH_zinc_N PF00107.21 KII83921.1 - 1e-28 99.5 0.2 1.6e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII83921.1 - 6.7e-18 65.8 0.1 1.7e-17 64.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII83921.1 - 1.1e-11 44.4 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KII83921.1 - 0.0071 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KII83921.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldolase_II PF00596.16 KII83922.1 - 2.8e-43 147.6 0.1 3.7e-43 147.2 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PTCB-BRCT PF12738.2 KII83923.1 - 1.3e-25 88.9 9.2 2.9e-17 62.2 0.2 4.4 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.21 KII83923.1 - 8.4e-23 80.3 0.2 3.3e-07 30.3 0.0 5.9 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain RabGAP-TBC PF00566.13 KII83924.1 - 1.4e-31 109.6 0.0 2.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.12 KII83925.1 - 4.4e-06 26.0 0.0 6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII83925.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Far-17a_AIG1 PF04750.9 KII83926.1 - 2.2e-05 23.7 12.1 3.1e-05 23.2 8.4 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Epimerase PF01370.16 KII83927.1 - 5.6e-18 65.2 0.1 9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KII83927.1 - 6.1e-09 35.1 4.3 6.7e-08 31.7 3.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KII83927.1 - 2.8e-08 32.8 0.1 4.1e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KII83927.1 - 2.8e-06 26.7 0.3 1e-05 24.9 0.6 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KII83927.1 - 5.7e-06 26.4 2.2 1.2e-05 25.4 1.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KII83927.1 - 5.7e-05 22.1 0.2 0.00011 21.1 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KII83927.1 - 0.0013 18.7 4.4 0.0032 17.3 2.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KII83927.1 - 0.028 13.2 0.2 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 KII83927.1 - 0.13 11.9 5.7 0.57 9.8 4.0 2.0 1 1 0 1 1 1 0 KR domain ECH PF00378.15 KII83928.1 - 3.8e-36 124.4 0.0 4.7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KII83928.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Aldedh PF00171.17 KII83929.1 - 1.9e-186 619.9 0.0 2.1e-186 619.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII83929.1 - 0.0016 17.2 0.0 0.0048 15.6 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KII83929.1 - 0.0036 16.5 0.0 0.93 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Mem_trans PF03547.13 KII83930.1 - 4.5e-34 117.3 3.8 5.8e-34 117.0 2.6 1.1 1 0 0 1 1 1 1 Membrane transport protein TAF PF02969.12 KII83931.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Pyridox_oxidase PF01243.15 KII83932.1 - 7.4e-06 25.8 0.0 0.026 14.5 0.0 3.1 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.7 KII83932.1 - 0.0046 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KII83932.1 - 0.048 14.2 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF485 PF04341.7 KII83933.1 - 5.4 6.7 8.3 5 6.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 GST_N_3 PF13417.1 KII83934.1 - 5e-11 42.6 0.0 8.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII83934.1 - 3.7e-07 29.9 0.1 7.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII83934.1 - 6.7e-06 26.5 0.0 4.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII83934.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 KII83934.1 - 0.00024 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_2 PF13409.1 KII83934.1 - 0.00052 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KII83934.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ATP_synt_I PF03899.10 KII83935.1 - 1.1 9.4 11.7 0.23 11.6 4.0 2.5 2 0 0 2 2 2 0 ATP synthase I chain Grp1_Fun34_YaaH PF01184.14 KII83936.1 - 7.1e-70 234.5 12.7 9e-70 234.2 8.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 KII83936.1 - 0.64 8.9 4.0 0.78 8.7 2.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PTR2 PF00854.16 KII83937.1 - 3.3e-41 141.3 6.4 3.3e-41 141.3 4.5 1.5 1 1 1 2 2 2 1 POT family Fasciclin PF02469.17 KII83938.1 - 2.3e-35 121.3 1.3 2.9e-22 79.0 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain NmrA PF05368.8 KII83940.1 - 4.1e-30 104.7 0.0 5.5e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII83940.1 - 5.8e-07 29.7 0.0 7.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII83940.1 - 0.073 12.4 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII83940.1 - 0.079 11.6 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_61 PF03443.9 KII83942.1 - 1.7e-54 184.9 0.0 2.7e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zn_clus PF00172.13 KII83943.1 - 6.3e-08 32.3 9.8 9.9e-08 31.7 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4592 PF15262.1 KII83945.1 - 0.079 13.5 0.2 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4592) GMC_oxred_N PF00732.14 KII83946.1 - 4.6e-47 160.5 0.1 6.1e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII83946.1 - 1.3e-33 116.3 0.0 2.1e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KII83946.1 - 5.1e-05 22.3 1.4 0.00018 20.5 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII83946.1 - 5.5e-05 22.2 0.1 8.7e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KII83946.1 - 0.00014 21.7 0.1 0.00039 20.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII83946.1 - 0.00027 19.8 0.2 0.013 14.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KII83946.1 - 0.0034 17.2 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII83946.1 - 0.083 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 KII83946.1 - 0.086 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 KII83946.1 - 0.12 12.3 0.2 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain HAD_2 PF13419.1 KII83947.1 - 5.7e-22 78.7 0.0 7.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII83947.1 - 1.9e-08 35.0 0.0 7.1e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII83947.1 - 0.00054 19.6 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like p450 PF00067.17 KII83948.1 - 2.7e-54 184.4 0.0 4e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PTR2 PF00854.16 KII83949.1 - 1e-41 143.0 10.3 4.5e-41 140.8 7.1 2.5 1 1 0 1 1 1 1 POT family DUF1469 PF07332.6 KII83949.1 - 0.0088 15.7 0.1 0.0088 15.7 0.0 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF1469) Glyco_hydro_31 PF01055.21 KII83953.1 - 1.7e-148 495.1 0.0 3.2e-131 438.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KII83953.1 - 3e-05 23.7 0.0 8.6e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like zf-C2H2 PF00096.21 KII83957.1 - 1.1 9.7 7.0 0.3 11.4 1.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short_C2 PF13561.1 KII83958.1 - 3.7e-30 105.4 0.5 4.5e-30 105.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII83958.1 - 1e-18 67.8 1.5 1.7e-18 67.1 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII83958.1 - 2.9e-08 33.5 0.3 4.7e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.16 KII83958.1 - 0.0053 16.0 0.1 0.0095 15.2 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Saccharop_dh PF03435.13 KII83958.1 - 0.039 12.9 0.1 0.068 12.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Flavodoxin_4 PF12682.2 KII83958.1 - 0.066 12.5 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin Ribosomal_L5 PF00281.14 KII83958.1 - 0.086 12.6 0.1 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L5 HMG_box PF00505.14 KII83959.1 - 1.7e-16 60.2 0.7 2.9e-16 59.5 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII83959.1 - 3.9e-13 49.5 0.3 7.9e-13 48.5 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain PNP_UDP_1 PF01048.15 KII83960.1 - 2.2e-24 85.7 0.0 3.1e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily F-box-like PF12937.2 KII83961.1 - 1.2e-06 28.1 1.4 2.8e-06 26.9 1.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII83961.1 - 0.0031 17.0 4.1 25 4.6 0.0 5.3 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII83961.1 - 0.13 11.9 12.4 0.48 10.2 0.0 6.0 6 1 1 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KII83961.1 - 1.4 9.2 3.9 75 3.8 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Epimerase PF01370.16 KII83962.1 - 6e-18 65.1 0.0 9.9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII83962.1 - 1.7e-11 43.3 0.0 2.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KII83962.1 - 6e-10 38.4 0.8 3.9e-08 32.5 0.6 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KII83962.1 - 1.1e-09 38.5 1.0 2.5e-09 37.3 0.7 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII83962.1 - 9.2e-08 31.6 0.0 4.7e-06 26.0 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KII83962.1 - 2.1e-05 24.4 1.4 8e-05 22.6 1.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KII83962.1 - 2.7e-05 23.2 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KII83962.1 - 0.0052 16.4 3.3 0.098 12.3 2.3 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KII83962.1 - 0.0096 14.8 0.1 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain GMP_synt_C PF00958.17 KII83962.1 - 0.028 14.1 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 GMP synthase C terminal domain F420_oxidored PF03807.12 KII83962.1 - 0.037 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_31 PF01055.21 KII83963.1 - 1.8e-162 541.1 2.3 2.4e-162 540.7 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_transf_90 PF05686.7 KII83965.1 - 1.3e-18 66.8 0.9 4.1e-16 58.6 0.0 3.5 3 1 0 3 3 3 3 Glycosyl transferase family 90 Glyco_hydro_28 PF00295.12 KII83966.1 - 2.5e-40 138.4 6.8 4e-40 137.7 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 p450 PF00067.17 KII83967.1 - 9.5e-47 159.5 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KII83968.1 - 1.3e-19 70.3 0.0 4.1e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase PEP_mutase PF13714.1 KII83968.1 - 0.041 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase p450 PF00067.17 KII83969.1 - 5.9e-45 153.6 0.0 7.7e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII83970.1 - 3.7e-49 167.5 0.0 4.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_F6 PF05511.6 KII83970.1 - 0.082 12.8 0.1 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 DUF3602 PF12223.3 KII83971.1 - 3.8e-15 56.0 16.3 7.4e-05 23.0 1.5 3.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) APC_CDC26 PF10471.4 KII83971.1 - 1 10.1 3.7 1.7 9.4 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 APG12 PF04110.8 KII83972.1 - 3.8e-31 107.1 0.1 4.9e-31 106.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KII83972.1 - 0.0034 17.3 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.6 KII83972.1 - 0.065 13.3 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain TBPIP PF07106.8 KII83974.1 - 1.6e-32 112.4 0.0 1.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2540 PF10802.3 KII83974.1 - 0.0061 16.2 0.1 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2540) Tyr-DNA_phospho PF06087.7 KII83975.1 - 4.6e-53 180.4 0.0 9e-53 179.4 0.0 1.5 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 KII83975.1 - 0.00023 20.4 3.2 0.00023 20.4 2.2 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif PLDc_2 PF13091.1 KII83975.1 - 0.0004 20.1 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain DUF4611 PF15387.1 KII83975.1 - 7.4 6.7 9.8 1.4 9.1 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Macoilin PF09726.4 KII83976.1 - 4.1 5.5 5.9 4.2 5.5 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein TrbC PF04956.8 KII83977.1 - 0.097 12.6 0.1 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family PAT1 PF09770.4 KII83977.1 - 4.8 5.2 8.7 5.4 5.1 6.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1469 PF07332.6 KII83978.1 - 1.4 8.6 7.4 0.38 10.4 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) ABC2_membrane_4 PF12730.2 KII83979.1 - 0.00037 19.7 2.1 0.00055 19.1 1.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein Pkinase PF00069.20 KII83984.1 - 2.4e-67 226.8 0.0 7.6e-65 218.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII83984.1 - 1.9e-32 112.3 0.0 1.8e-29 102.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII83984.1 - 1.7e-05 23.9 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII83984.1 - 4.5e-05 22.5 0.0 8.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII83984.1 - 0.00012 21.9 0.1 0.00043 20.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KII83984.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleoplasmin PF03066.10 KII83984.1 - 1.8 8.0 6.3 0.25 10.8 0.5 2.0 2 0 0 2 2 2 0 Nucleoplasmin Dabb PF07876.7 KII83985.1 - 2e-15 57.0 0.0 2.4e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.11 KII83985.1 - 0.0025 17.7 0.0 0.007 16.3 0.0 1.8 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase TraL PF07178.6 KII83988.1 - 0.96 9.5 0.0 0.96 9.5 0.0 3.2 2 1 1 3 3 3 0 TraL protein BTB PF00651.26 KII83993.1 - 3.9e-10 39.6 0.1 9.4e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain COX15-CtaA PF02628.10 KII83994.1 - 0.00086 18.2 6.1 0.001 18.0 4.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Tcell_CD4_Cterm PF12104.3 KII83995.1 - 0.16 11.5 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region DUF2537 PF10801.3 KII83996.1 - 0.05 13.7 1.3 0.05 13.7 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2537) MgtE PF01769.11 KII83996.1 - 0.17 12.1 15.1 1 9.6 2.7 2.2 1 1 0 2 2 2 0 Divalent cation transporter tRNA-synt_2b PF00587.20 KII83997.1 - 2.4e-65 219.3 0.0 4.8e-65 218.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KII83997.1 - 3.3e-21 75.0 0.0 7e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain S-antigen PF05756.6 KII84001.1 - 4.4 7.3 8.8 7.4 6.6 6.1 1.3 1 0 0 1 1 1 0 S-antigen protein DUF2665 PF11654.3 KII84002.1 - 0.42 10.2 2.3 22 4.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2665) BTB PF00651.26 KII84003.1 - 5.1e-10 39.3 0.0 1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Collagen PF01391.13 KII84005.1 - 0.025 14.1 5.5 0.025 14.1 3.8 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Flagellin_C PF00700.16 KII84006.1 - 0.54 10.4 7.8 2.4 8.3 0.6 3.1 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region APG6 PF04111.7 KII84006.1 - 1.2 8.0 7.8 1.9 7.4 5.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 KII84008.1 - 2.7e-11 43.4 0.0 5.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1639 PF07797.9 KII84008.1 - 0.37 10.2 2.3 0.73 9.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) BTB PF00651.26 KII84009.1 - 2.6e-08 33.8 0.0 6.8e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KII84010.1 - 7.4e-11 42.0 0.0 1.9e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KII84011.1 - 7.8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Bestrophin PF01062.16 KII84012.1 - 4.3e-49 167.0 3.9 8.8e-31 106.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel O-ag_pol_Wzy PF14296.1 KII84012.1 - 0.038 12.5 6.8 0.2 10.1 1.2 2.1 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy FMO-like PF00743.14 KII84013.1 - 1e-22 80.0 0.0 4.7e-12 44.8 0.0 4.0 4 0 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII84013.1 - 8.2e-14 52.1 0.0 9.6e-13 48.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII84013.1 - 7.5e-09 35.4 0.2 2.3e-07 30.7 0.0 3.1 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII84013.1 - 2.5e-07 30.7 0.0 0.00031 20.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KII84013.1 - 1.4e-05 24.7 0.0 3.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KII84013.1 - 4.5e-05 22.6 0.2 0.0025 16.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KII84013.1 - 9.2e-05 21.4 0.0 0.00045 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KII84013.1 - 0.00018 21.5 0.2 0.038 14.0 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 KII84013.1 - 0.00035 19.5 0.1 0.06 12.2 0.0 3.1 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KII84013.1 - 0.0004 20.2 2.0 0.0078 15.9 0.0 3.5 4 1 1 5 5 4 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KII84013.1 - 0.00071 18.1 0.3 0.0016 16.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KII84013.1 - 0.001 18.1 0.1 0.075 12.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KII84013.1 - 0.0012 19.0 0.3 0.052 13.7 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 KII84013.1 - 0.0048 16.0 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KII84013.1 - 0.01 14.9 0.1 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KII84013.1 - 0.012 15.3 0.3 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII84013.1 - 0.012 14.7 0.1 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KII84013.1 - 0.025 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A CPSase_L_chain PF00289.17 KII84013.1 - 0.029 14.4 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pyr_redox PF00070.22 KII84013.1 - 0.038 14.4 0.0 0.82 10.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII84013.1 - 0.056 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TraF PF13728.1 KII84013.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein Rhodanese PF00581.15 KII84014.1 - 5.3e-20 71.8 0.0 2.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain SSF PF00474.12 KII84015.1 - 1.7e-19 69.7 32.4 1.7e-19 69.7 22.4 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family zf-C2H2 PF00096.21 KII84016.1 - 0.012 15.8 2.2 0.033 14.5 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII84016.1 - 0.45 10.9 3.9 0.91 10.0 2.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger BTB PF00651.26 KII84017.1 - 4.1e-10 39.6 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain EBP PF05241.7 KII84018.1 - 3.3e-12 45.8 9.4 4.7e-12 45.3 6.5 1.2 1 0 0 1 1 1 1 Emopamil binding protein Pyr_redox_3 PF13738.1 KII84019.1 - 1.6e-20 74.0 0.0 1.5e-19 70.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII84019.1 - 3e-18 65.3 0.0 9.6e-18 63.6 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KII84019.1 - 9.5e-12 44.4 0.1 1.4e-07 30.8 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII84019.1 - 3.6e-08 33.5 0.0 7.9e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KII84019.1 - 2.6e-06 27.5 0.1 0.0014 18.7 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KII84019.1 - 9.4e-06 25.9 0.1 0.11 12.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII84019.1 - 0.00022 21.0 0.9 0.61 9.8 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 KII84019.1 - 0.00024 20.1 0.0 0.47 9.2 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase TrkA_N PF02254.13 KII84019.1 - 0.0014 18.5 0.0 0.066 13.2 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 KII84019.1 - 0.0061 16.7 0.0 1.5 9.1 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KII84019.1 - 0.019 14.1 0.1 0.19 10.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 KII84019.1 - 0.024 14.7 0.1 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain SnoaL_3 PF13474.1 KII84019.1 - 0.028 14.4 0.3 0.29 11.1 0.1 2.7 3 0 0 3 3 3 0 SnoaL-like domain 3HCDH_N PF02737.13 KII84019.1 - 0.065 12.8 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SSF PF00474.12 KII84020.1 - 6.1e-18 64.6 35.3 6.1e-18 64.6 24.5 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family BTB PF00651.26 KII84021.1 - 6.2e-07 29.4 0.1 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pyr_redox_3 PF13738.1 KII84022.1 - 7.5e-23 81.6 0.0 2e-22 80.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII84022.1 - 3.6e-18 65.0 0.0 2.3e-17 62.4 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KII84022.1 - 8.7e-11 41.3 0.0 1.3e-08 34.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII84022.1 - 7.8e-07 29.1 0.0 5e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII84022.1 - 3.8e-06 27.2 0.0 0.03 14.7 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KII84022.1 - 7e-06 26.1 0.1 0.00013 22.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KII84022.1 - 6.2e-05 22.9 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_8 PF13450.1 KII84022.1 - 0.0013 18.7 0.0 0.025 14.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KII84022.1 - 0.028 13.5 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KII84022.1 - 0.045 13.9 0.0 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 KII84022.1 - 0.046 12.6 0.0 13 4.5 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase CPSase_L_chain PF00289.17 KII84022.1 - 0.051 13.6 0.2 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HI0933_like PF03486.9 KII84022.1 - 0.073 11.5 0.0 0.23 9.9 0.0 1.8 1 0 0 1 1 1 0 HI0933-like protein HARP PF07443.8 KII84022.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 HepA-related protein (HARP) 3HCDH_N PF02737.13 KII84022.1 - 0.19 11.3 0.0 24 4.5 0.0 2.5 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box PF00646.28 KII84026.1 - 1.5e-06 27.7 0.3 6.9e-06 25.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII84026.1 - 0.00093 18.8 0.3 0.0059 16.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like ParBc PF02195.13 KII84027.1 - 0.021 14.9 0.3 0.042 13.9 0.0 1.7 2 0 0 2 2 2 0 ParB-like nuclease domain Mrr_N PF14338.1 KII84028.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Mrr N-terminal domain SUR7 PF06687.7 KII84029.1 - 2.9e-15 56.4 19.0 1.4e-14 54.1 12.6 2.3 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KII84029.1 - 2.7e-05 23.9 5.8 2.7e-05 23.9 4.0 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 KII84029.1 - 0.00032 20.6 0.0 0.00032 20.6 0.0 1.9 3 0 0 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 PMP22_Claudin PF00822.15 KII84029.1 - 0.0092 15.6 5.0 0.021 14.4 3.3 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DuoxA PF10204.4 KII84029.1 - 0.023 13.7 1.9 0.037 13.0 1.3 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF2207 PF09972.4 KII84029.1 - 0.088 11.3 0.2 0.13 10.7 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amastin PF07344.6 KII84029.1 - 0.98 9.0 9.7 0.94 9.0 3.5 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein Tad PF13400.1 KII84029.1 - 2.3 8.3 10.0 0.26 11.3 0.4 3.0 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Glyco_hydro_30 PF02055.11 KII84031.1 - 3.5e-29 101.3 0.1 4.8e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KII84031.1 - 2.6e-05 23.3 0.0 0.092 11.6 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Asp PF00026.18 KII84032.1 - 2.4e-52 178.1 18.7 3e-52 177.8 13.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII84032.1 - 7.2e-06 26.4 7.8 0.0018 18.7 1.7 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KII84032.1 - 1.2e-05 25.3 10.6 2.9e-05 24.0 5.7 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KII84032.1 - 0.0063 16.0 0.3 0.36 10.3 0.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 KII84032.1 - 0.093 12.6 1.2 9 6.2 0.1 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KII84032.1 - 0.1 12.4 0.9 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Uds1 PF15456.1 KII84034.1 - 0.088 12.7 1.5 0.13 12.2 1.1 1.4 1 1 0 1 1 1 0 Up-regulated During Septation DUF1843 PF08898.5 KII84034.1 - 0.74 9.9 5.7 0.19 11.7 0.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF1192 PF06698.6 KII84034.1 - 1.5 8.6 6.5 0.71 9.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) F-box-like PF12937.2 KII84036.1 - 7.9e-05 22.3 0.3 0.00022 20.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KII84036.1 - 0.013 15.2 9.0 4.4 7.1 0.1 5.2 3 2 3 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 KII84036.1 - 0.16 11.6 10.1 6.2 6.5 0.4 5.2 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KII84036.1 - 0.21 11.7 1.4 96 3.5 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat SSF PF00474.12 KII84039.1 - 2.6e-17 62.5 21.9 2.6e-17 62.5 15.2 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family TMEM173 PF15009.1 KII84039.1 - 0.11 11.3 1.6 0.65 8.7 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 173 Amidase PF01425.16 KII84040.1 - 1.6e-99 333.7 0.1 2e-99 333.4 0.1 1.0 1 0 0 1 1 1 1 Amidase SSF PF00474.12 KII84041.1 - 7.5e-24 84.1 25.7 1.2e-23 83.4 17.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family RrnaAD PF00398.15 KII84043.1 - 1e-53 182.0 0.0 1.3e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KII84043.1 - 2.9e-10 40.1 0.0 4.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII84043.1 - 9.2e-07 29.4 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII84043.1 - 4.3e-05 23.1 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KII84043.1 - 0.0001 21.7 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KII84043.1 - 0.00023 20.9 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII84043.1 - 0.00027 21.3 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KII84043.1 - 0.00028 20.4 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KII84043.1 - 0.00077 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 KII84043.1 - 0.00082 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KII84043.1 - 0.00092 19.6 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KII84043.1 - 0.014 14.9 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein DREV PF05219.7 KII84043.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 KII84043.1 - 0.036 13.1 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SUI1 PF01253.17 KII84045.1 - 4.2e-11 42.4 0.0 7.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 KII84045.1 - 3.1e-07 29.9 0.1 8.2e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 PUA domain SWIB PF02201.13 KII84045.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain Kelch_4 PF13418.1 KII84047.1 - 1.3e-48 162.4 25.5 1.1e-10 41.1 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KII84047.1 - 6.7e-41 137.5 30.3 3.2e-09 36.6 0.4 7.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KII84047.1 - 7.9e-32 108.5 14.1 3.7e-06 26.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KII84047.1 - 9e-32 108.5 12.1 2.8e-08 33.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KII84047.1 - 4.8e-30 102.4 16.4 9.6e-06 25.5 0.1 6.7 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KII84047.1 - 1.9e-21 74.9 14.9 6.5e-06 25.7 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Abhydrolase_6 PF12697.2 KII84049.1 - 3e-09 37.0 0.1 6.6e-09 35.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII84049.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transp_Tc5_C PF04236.10 KII84050.1 - 0.02 15.1 1.0 0.02 15.1 0.7 1.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-UBR PF02207.15 KII84055.1 - 0.0039 16.8 1.5 0.013 15.1 1.0 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.19 KII84055.1 - 0.011 15.5 3.1 0.011 15.5 2.2 2.1 2 0 0 2 2 2 0 B-box zinc finger Tet_JBP PF12851.2 KII84058.1 - 2.5e-06 26.8 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily FGGY_C PF02782.11 KII84058.1 - 0.006 16.2 0.1 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 KII84058.1 - 0.035 14.6 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cauli_VI PF01693.11 KII84060.1 - 3e-05 23.9 0.2 5.9e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Caulimovirus viroplasmin PSCyt2 PF07583.6 KII84061.1 - 0.049 13.1 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) SurE PF01975.12 KII84065.1 - 1.3e-36 125.8 0.2 2e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Survival protein SurE Amino_oxidase PF01593.19 KII84066.1 - 2e-33 116.1 0.0 3.5e-33 115.3 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII84066.1 - 2.9e-06 27.2 0.0 8.7e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KII84067.1 - 5.3e-24 85.1 0.0 6.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Fungal_trans PF04082.13 KII84068.1 - 1.3e-22 79.9 0.0 2.3e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84068.1 - 8.2e-10 38.4 5.6 1.4e-09 37.7 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.12 KII84069.1 - 1.8e-36 125.3 0.4 2.4e-36 124.8 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE Peripla_BP_4 PF13407.1 KII84069.1 - 0.024 13.9 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain HMG_box PF00505.14 KII84070.1 - 1.9e-23 82.4 0.6 3.3e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII84070.1 - 2.1e-19 69.6 1.2 2.1e-19 69.6 0.9 1.7 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.7 KII84070.1 - 0.0012 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.8 KII84070.1 - 0.0022 18.2 0.3 0.0034 17.6 0.1 1.4 1 1 0 1 1 1 1 YABBY protein HMG_box_5 PF14887.1 KII84070.1 - 0.035 13.9 6.6 0.016 15.0 2.2 2.0 1 1 1 2 2 2 0 HMG (high mobility group) box 5 DUF4615 PF15393.1 KII84070.1 - 0.14 12.3 2.1 0.19 11.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Vpu PF00558.14 KII84071.1 - 4.2 6.9 7.2 0.37 10.3 0.4 2.5 2 1 1 3 3 3 0 Vpu protein EAP30 PF04157.11 KII84072.1 - 3.3e-56 189.9 0.1 3.7e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4423 PF14394.1 KII84072.1 - 0.01 15.3 0.2 0.045 13.3 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4423) AA_permease PF00324.16 KII84073.1 - 1.2e-122 409.7 35.2 1.3e-122 409.5 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII84073.1 - 5.6e-34 117.3 41.3 7.6e-34 116.9 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.14 KII84074.1 - 1.8e-22 79.9 0.0 9.2e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KII84074.1 - 6e-05 22.9 0.4 0.00014 21.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KII84074.1 - 0.017 13.5 0.3 0.16 10.4 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 KII84074.1 - 0.026 13.4 0.2 0.043 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII84074.1 - 0.027 13.3 0.2 0.051 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KII84074.1 - 0.065 13.0 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KII84074.1 - 0.087 11.4 0.7 0.35 9.4 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.5 KII84074.1 - 0.12 11.1 0.0 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase F-box PF00646.28 KII84075.1 - 0.00099 18.7 0.0 0.0035 16.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain DUF3494 PF11999.3 KII84076.1 - 1.1e-54 185.2 21.7 1.1e-54 185.2 15.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF2844 PF11005.3 KII84076.1 - 0.085 12.6 1.3 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) DPBB_1 PF03330.13 KII84077.1 - 9.4e-10 38.3 0.3 2.2e-09 37.1 0.2 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 KII84079.1 - 7.5e-07 29.0 0.1 1.1e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SNF2_N PF00176.18 KII84080.1 - 0.032 13.0 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain TSKS PF15358.1 KII84080.1 - 0.99 7.4 5.5 1.5 6.8 3.8 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF605 PF04652.11 KII84080.1 - 9.5 5.5 27.3 1.1 8.6 15.6 1.6 2 0 0 2 2 2 0 Vta1 like SNF2_N PF00176.18 KII84081.1 - 4.1e-36 124.2 0.0 6.4e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII84081.1 - 3.8e-15 55.5 0.0 3.2e-13 49.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KII84081.1 - 0.0019 17.0 0.0 0.014 14.1 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 VIGSSK PF14773.1 KII84081.1 - 0.017 14.9 0.1 0.017 14.9 0.0 2.1 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal SEC-C PF02810.10 KII84081.1 - 0.61 9.6 8.1 0.05 13.1 2.2 1.8 2 0 0 2 2 2 0 SEC-C motif Peptidase_C65 PF10275.4 KII84082.1 - 5.3e-61 206.0 0.0 6.5e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 KII84082.1 - 0.0067 17.0 0.0 0.23 12.0 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease PseudoU_synth_1 PF01416.15 KII84083.1 - 4.7e-27 94.4 0.0 4.7e-18 65.5 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase Peptidase_M28 PF04389.12 KII84088.1 - 1.3e-28 99.9 0.0 2.7e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KII84088.1 - 0.0002 20.9 0.1 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 p450 PF00067.17 KII84091.1 - 6.7e-69 232.5 0.0 1.4e-68 231.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Oxysterol_BP PF01237.13 KII84092.1 - 2e-74 250.2 0.1 7.1e-74 248.4 0.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein p450 PF00067.17 KII84093.1 - 5.7e-59 199.8 0.0 1.3e-58 198.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII84094.1 - 7.9e-59 199.3 0.0 2e-58 198.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Birna_RdRp PF04197.7 KII84094.1 - 0.0057 14.7 0.0 0.0076 14.3 0.0 1.1 1 0 0 1 1 1 1 Birnavirus RNA dependent RNA polymerase (VP1) F-box-like PF12937.2 KII84095.1 - 4e-05 23.2 0.7 0.00011 21.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KII84095.1 - 0.12 12.0 0.5 1.5 8.4 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) COX5B PF01215.14 KII84096.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Mem_trans PF03547.13 KII84097.1 - 3.5e-10 38.7 4.7 3.6e-09 35.3 2.2 2.9 1 1 1 2 2 2 2 Membrane transport protein Aminotran_1_2 PF00155.16 KII84100.1 - 7.2e-24 84.4 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF772 PF05598.6 KII84101.1 - 0.084 12.7 0.1 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Transposase domain (DUF772) DPBB_1 PF03330.13 KII84103.1 - 0.0001 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel UQ_con PF00179.21 KII84104.1 - 2.8e-46 156.4 0.0 3.2e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII84104.1 - 0.00056 19.6 0.0 0.0028 17.4 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B RNA_pol_Rpb2_6 PF00562.23 KII84105.1 - 1.1e-119 399.7 0.2 1.5e-119 399.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KII84105.1 - 2.7e-56 189.7 0.0 1.1e-55 187.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KII84105.1 - 1.3e-29 103.0 0.1 2.9e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KII84105.1 - 4.1e-29 100.6 0.1 1.2e-28 99.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KII84105.1 - 2.9e-23 81.4 1.0 8.8e-23 79.8 0.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KII84105.1 - 6.1e-21 73.9 0.0 1.6e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KII84105.1 - 3.3e-13 49.3 0.1 7.9e-13 48.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.21 KII84106.1 - 1.4e-44 150.8 0.0 1.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ALO PF04030.9 KII84107.1 - 9.9e-81 271.1 0.0 1.8e-80 270.3 0.0 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KII84107.1 - 5.8e-29 100.3 0.2 9.3e-29 99.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.15 KII84108.1 - 0.00014 19.9 0.0 0.00023 19.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KII84108.1 - 0.31 9.5 0.0 0.52 8.8 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Noc2 PF03715.8 KII84111.1 - 6e-102 340.5 0.2 1e-100 336.5 0.0 2.1 2 0 0 2 2 2 1 Noc2p family SDA1 PF05285.7 KII84111.1 - 0.075 12.3 11.2 0.14 11.4 7.8 1.3 1 0 0 1 1 1 0 SDA1 MT-A70 PF05063.9 KII84112.1 - 1.1e-37 129.2 0.0 2.7e-37 128.0 0.0 1.6 1 1 0 1 1 1 1 MT-A70 Got1 PF04178.7 KII84113.1 - 5.8e-29 100.6 12.1 7.6e-29 100.2 8.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Acyl_transf_3 PF01757.17 KII84113.1 - 0.15 10.8 14.6 0.2 10.4 10.1 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF4396 PF14342.1 KII84113.1 - 0.88 9.6 5.1 2.1 8.4 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) MtN3_slv PF03083.11 KII84113.1 - 1.5 8.7 4.8 2.8 7.8 3.3 1.5 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF3414 PF11894.3 KII84114.1 - 1.2e-271 904.2 0.0 1.6e-271 903.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Hexapep PF00132.19 KII84115.1 - 2.8e-08 32.8 18.1 0.0032 16.9 0.2 4.4 3 2 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KII84115.1 - 0.091 12.3 13.7 0.05 13.1 3.7 2.8 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF342 PF03961.8 KII84115.1 - 0.51 8.6 2.5 0.63 8.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CMD PF02627.15 KII84116.1 - 0.0081 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Herpes_IE2_3 PF03361.9 KII84116.1 - 0.092 12.0 0.1 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Metallophos PF00149.23 KII84117.1 - 1.6e-10 40.7 6.6 1.1e-09 38.0 4.6 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII84117.1 - 7e-10 38.9 0.0 2.2e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mem_trans PF03547.13 KII84118.1 - 2.6e-19 68.7 11.6 3e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein Abhydrolase_6 PF12697.2 KII84119.1 - 8.4e-25 87.9 1.2 1e-24 87.7 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII84119.1 - 6.9e-15 55.2 0.0 1.3e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII84119.1 - 8.5e-06 25.5 0.0 1.3e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KII84119.1 - 0.0046 17.2 0.1 0.009 16.2 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KII84119.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 KII84119.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.20 KII84119.1 - 0.062 12.9 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) 3-alpha PF03475.9 KII84120.1 - 0.0084 15.8 0.1 1.5 8.5 0.1 2.7 2 0 0 2 2 2 2 3-alpha domain GreA_GreB_N PF03449.10 KII84120.1 - 0.033 14.2 1.2 27 4.9 0.0 3.2 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal EI24 PF07264.6 KII84121.1 - 2e-08 33.9 6.5 3.2e-08 33.2 4.5 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3325 PF11804.3 KII84121.1 - 0.023 14.6 2.9 0.023 14.6 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) AAA_11 PF13086.1 KII84122.1 - 2.8e-15 56.5 0.0 8.3e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KII84122.1 - 1.4e-12 47.6 0.0 7.9e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII84122.1 - 2.5e-11 43.1 0.0 4.5e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_12 PF13087.1 KII84122.1 - 2e-10 40.3 0.0 5.4e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII84122.1 - 4.9e-05 23.4 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KII84122.1 - 0.00092 19.4 0.0 0.0026 17.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KII84122.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KII84122.1 - 0.0067 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.9 KII84122.1 - 0.014 15.0 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_22 PF13401.1 KII84122.1 - 0.016 15.3 0.2 0.13 12.4 0.1 2.6 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 KII84122.1 - 0.056 12.8 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KII84122.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 KII84122.1 - 0.059 12.2 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C PF13361.1 KII84122.1 - 0.059 12.8 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KII84122.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_17 PF13207.1 KII84122.1 - 0.092 13.5 0.3 0.38 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain tRNA-synt_1 PF00133.17 KII84124.1 - 5.3e-34 117.2 0.2 1.6e-15 56.1 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KII84124.1 - 7.5e-17 61.0 0.0 1.4e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KII84124.1 - 4.2e-14 52.5 0.0 9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KII84124.1 - 1.1e-07 31.3 0.0 2.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Peptidase_M50 PF02163.17 KII84125.1 - 2.1e-13 49.6 0.1 3.7e-13 48.8 0.0 1.3 2 0 0 2 2 2 1 Peptidase family M50 PDZ PF00595.19 KII84125.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KII84125.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain YyzF PF14116.1 KII84127.1 - 0.55 10.2 3.1 21 5.1 0.1 3.6 3 0 0 3 3 3 0 YyzF-like protein MFS_1 PF07690.11 KII84128.1 - 3.6e-25 88.4 52.4 3.6e-25 88.4 36.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KII84128.1 - 3e-11 42.2 18.5 5.8e-11 41.3 12.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KII84128.1 - 1.1e-06 27.5 7.8 1.1e-06 27.5 5.4 3.4 3 0 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.17 KII84130.1 - 4.4e-34 117.7 0.0 1.4e-33 116.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KII84131.1 - 1.2e-61 208.5 0.0 1.7e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII84131.1 - 3.5e-36 124.6 0.2 1.1e-35 123.0 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KII84131.1 - 2.7e-05 23.2 1.5 6.7e-05 21.9 0.7 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII84131.1 - 0.00023 21.1 0.0 0.0007 19.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII84131.1 - 0.0017 17.3 0.3 0.0053 15.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KII84131.1 - 0.0022 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KII84131.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII84131.1 - 0.16 10.4 0.1 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KII84131.1 - 0.16 12.3 0.3 0.37 11.2 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KII84133.1 - 6.8e-29 100.6 54.4 6.8e-29 100.6 37.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KII84133.1 - 1.4e-12 46.6 19.2 2.2e-12 45.9 13.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KII84133.1 - 1.9e-08 33.3 10.0 1.9e-08 33.3 6.9 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter S1FA PF04689.8 KII84133.1 - 3.2 7.6 8.0 2.1 8.3 0.2 3.0 3 0 0 3 3 3 0 DNA binding protein S1FA Acetyltransf_1 PF00583.19 KII84134.1 - 5.9e-15 55.0 0.0 9.4e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII84134.1 - 2e-07 31.1 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII84134.1 - 4.2e-07 29.6 0.1 6.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KII84134.1 - 1.3e-05 25.3 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII84134.1 - 3.5e-05 23.8 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII84134.1 - 7.5e-05 22.6 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII84134.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KII84134.1 - 0.004 16.7 0.1 0.0054 16.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HSP70 PF00012.15 KII84135.1 - 7.3e-267 886.1 7.4 8.3e-267 885.9 5.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KII84135.1 - 3.5e-18 65.2 1.7 1.8e-17 62.9 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KII84135.1 - 0.00029 19.7 0.5 0.029 13.2 0.2 2.4 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KII84135.1 - 0.047 12.7 0.1 0.047 12.7 0.1 3.0 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KII84135.1 - 6 6.7 6.9 36 4.2 0.2 3.9 3 1 0 3 3 3 0 Cell division protein FtsA AA_permease_2 PF13520.1 KII84137.1 - 8.6e-62 209.0 55.6 1.1e-61 208.6 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII84137.1 - 2.2e-17 62.5 48.3 3.6e-17 61.8 33.5 1.3 1 0 0 1 1 1 1 Amino acid permease COX7B PF05392.6 KII84137.1 - 0.036 13.6 0.1 0.095 12.2 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB DUF4293 PF14126.1 KII84137.1 - 0.056 13.3 2.5 0.14 12.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Mem_trans PF03547.13 KII84138.1 - 1.1e-25 89.7 6.0 1.5e-12 46.5 4.4 2.0 2 0 0 2 2 2 2 Membrane transport protein STE3 PF02076.10 KII84139.1 - 8.5e-67 225.1 18.7 1e-66 224.9 13.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor Ead_Ea22 PF13935.1 KII84140.1 - 0.015 15.6 1.0 0.045 14.0 0.7 1.7 2 0 0 2 2 2 0 Ead/Ea22-like protein FlaC_arch PF05377.6 KII84140.1 - 0.061 13.2 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) RP-C_C PF11800.3 KII84140.1 - 0.083 12.5 1.5 0.72 9.5 0.5 2.3 2 1 0 2 2 2 0 Replication protein C C-terminal region F_actin_bind PF08919.5 KII84140.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 F-actin binding Uds1 PF15456.1 KII84140.1 - 5.2 7.0 7.6 2.6 8.0 0.1 3.0 2 1 0 3 3 3 0 Up-regulated During Septation Methyltransf_2 PF00891.13 KII84142.1 - 7.7e-34 116.9 0.0 1.2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII84142.1 - 0.00019 22.0 0.0 0.00041 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII84142.1 - 0.00038 20.2 0.0 0.00085 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII84142.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KII84142.1 - 0.011 15.3 0.1 0.15 11.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain STE3 PF02076.10 KII84143.1 - 1.1e-104 349.5 16.0 1.3e-104 349.2 11.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor SNF2_N PF00176.18 KII84144.1 - 2.6e-41 141.3 0.0 4.7e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KII84144.1 - 2.2e-06 27.2 9.8 4.1e-06 26.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII84144.1 - 5.4e-06 26.1 13.8 5.4e-06 26.1 9.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII84144.1 - 1.2e-05 25.2 12.1 2.2e-05 24.4 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII84144.1 - 3.7e-05 23.3 13.9 6.6e-05 22.5 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII84144.1 - 6.6e-05 22.5 12.6 0.00013 21.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII84144.1 - 0.016 15.3 10.8 0.044 13.9 7.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KII84144.1 - 0.31 10.8 6.3 0.95 9.3 4.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KII84144.1 - 0.57 10.1 10.4 1.2 9.1 7.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-binding PF00249.26 KII84145.1 - 4.6e-17 61.8 0.2 1.6e-09 37.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII84145.1 - 8.6e-12 44.9 0.2 2.2e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain PCI PF01399.22 KII84146.1 - 8.1e-09 35.7 0.0 2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain zf-MYND PF01753.13 KII84148.1 - 0.00064 19.5 9.4 0.002 17.9 6.5 1.9 1 1 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KII84148.1 - 0.021 14.4 4.9 0.021 14.4 3.4 2.5 3 0 0 3 3 3 0 HIT zinc finger zf-ribbon_3 PF13248.1 KII84148.1 - 0.073 12.3 2.6 0.094 11.9 0.1 2.4 1 1 1 2 2 2 0 zinc-ribbon domain AA_permease_2 PF13520.1 KII84149.1 - 3.6e-42 144.3 48.4 1.2e-22 80.0 10.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KII84149.1 - 4.3e-18 64.9 42.6 7.6e-12 44.3 14.1 2.1 2 0 0 2 2 2 2 Amino acid permease Imm37 PF15598.1 KII84150.1 - 0.086 12.6 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 37 ACPS PF01648.15 KII84150.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily LPAM_2 PF13627.1 KII84151.1 - 6.1 6.6 6.5 32 4.3 4.5 2.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Cyclin PF08613.6 KII84152.1 - 0.005 17.2 0.6 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin Zip PF02535.17 KII84152.1 - 0.018 14.0 5.4 0.018 14.0 3.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Gag_spuma PF03276.9 KII84152.1 - 0.17 10.1 2.1 0.18 10.1 1.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF755 PF05501.6 KII84152.1 - 6.9 6.7 12.4 9.2 6.3 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MFS_1 PF07690.11 KII84153.1 - 5.5e-37 127.3 30.4 5.5e-37 127.3 21.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII84153.1 - 8.7e-12 44.3 14.8 1.7e-11 43.3 10.3 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KII84153.1 - 4e-05 21.9 7.6 4.4e-05 21.7 4.8 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector DUF3382 PF11862.3 KII84153.1 - 0.015 15.1 0.8 0.015 15.1 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Transgly_assoc PF04226.8 KII84153.1 - 4.3 7.4 16.3 3.2 7.8 6.3 3.2 3 0 0 3 3 3 0 Transglycosylase associated protein UbiA PF01040.13 KII84154.1 - 1e-15 57.6 6.7 1.3e-15 57.3 4.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3329 PF11808.3 KII84154.1 - 0.021 14.8 1.3 0.058 13.4 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) zf-MYND PF01753.13 KII84155.1 - 1.5e-11 43.9 18.6 1.5e-11 43.9 12.9 2.5 3 0 0 3 3 3 1 MYND finger MGC-24 PF05283.6 KII84155.1 - 0.037 13.8 5.2 0.062 13.1 3.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Peptidase_S9 PF00326.16 KII84157.1 - 3.3e-31 108.1 0.0 4.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII84157.1 - 2e-08 34.0 0.1 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII84157.1 - 9.2e-05 22.4 0.2 0.00031 20.7 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KII84157.1 - 0.0018 17.9 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KII84157.1 - 0.0082 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KII84157.1 - 0.024 13.8 0.0 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family La PF05383.12 KII84158.1 - 1.5e-17 63.1 0.0 3.2e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KII84158.1 - 0.00015 21.3 0.1 0.00039 19.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII84158.1 - 0.0003 20.6 0.0 0.00083 19.1 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 KII84158.1 - 0.00043 20.2 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PalH PF08733.5 KII84160.1 - 1.1 7.9 15.7 1.5 7.5 10.9 1.2 1 0 0 1 1 1 0 PalH/RIM21 p450 PF00067.17 KII84162.1 - 8.4e-69 232.2 0.0 9.5e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 KII84163.1 - 1.1e-26 93.7 0.1 1.7e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KII84163.1 - 3.8e-11 42.2 0.0 8.9e-11 41.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) ADH_zinc_N PF00107.21 KII84164.1 - 1.6e-24 85.9 0.0 3.4e-24 84.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII84164.1 - 2e-11 43.6 0.1 1.4e-09 37.6 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII84164.1 - 2e-10 41.6 0.0 6.4e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_61 PF03443.9 KII84165.1 - 2.7e-62 210.4 0.0 3e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 KII84166.1 - 2.1e-44 151.7 21.5 3.6e-44 150.9 14.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4564 PF15169.1 KII84166.1 - 0.064 12.9 0.4 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Gln-synt_C PF00120.19 KII84167.1 - 0.0014 17.8 0.1 0.0017 17.5 0.1 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Cast PF10174.4 KII84167.1 - 0.017 13.1 0.3 0.021 12.8 0.2 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IFT20 PF14931.1 KII84167.1 - 0.12 12.2 0.8 0.19 11.6 0.6 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Uso1_p115_C PF04871.8 KII84167.1 - 0.12 12.3 0.8 0.2 11.5 0.5 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA PF00004.24 KII84168.1 - 2.7e-19 69.6 0.0 1.5e-17 64.0 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KII84168.1 - 7.7e-12 45.2 4.7 6.6e-06 25.8 0.3 2.7 2 1 1 3 3 3 2 BCS1 N terminal AAA_11 PF13086.1 KII84168.1 - 2.4e-05 24.0 0.0 6.6e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII84168.1 - 9.8e-05 22.0 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KII84168.1 - 0.00041 21.1 0.1 0.0015 19.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KII84168.1 - 0.0058 15.7 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KII84168.1 - 0.014 15.3 0.8 0.047 13.6 0.0 2.0 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 KII84168.1 - 0.014 15.5 0.1 0.077 13.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 KII84168.1 - 0.039 12.6 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 KII84168.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KII84168.1 - 0.057 13.7 0.2 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KII84168.1 - 0.059 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 KII84168.1 - 0.063 13.1 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KII84168.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 KII84168.1 - 0.12 12.3 1.2 0.95 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.6 KII84168.1 - 0.16 11.5 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KII84169.1 - 1.1e-16 61.1 0.1 1.2e-14 54.6 0.1 3.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KII84169.1 - 7.8e-16 58.2 4.2 1.9e-08 34.1 0.4 2.5 1 1 1 2 2 2 2 BCS1 N terminal AAA_11 PF13086.1 KII84169.1 - 0.00013 21.6 0.9 0.0007 19.2 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII84169.1 - 0.00029 21.6 0.4 0.0029 18.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII84169.1 - 0.00033 20.3 0.1 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KII84169.1 - 0.0085 16.2 0.0 0.093 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII84169.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KII84169.1 - 0.014 15.2 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KII84169.1 - 0.02 14.5 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KII84169.1 - 0.027 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KII84169.1 - 0.038 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KII84169.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 KII84169.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 KII84170.1 - 8e-50 168.3 0.0 9.5e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII84170.1 - 8.5e-18 64.9 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII84170.1 - 4.4e-07 29.3 0.0 6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KII84170.1 - 0.017 14.3 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KII84170.1 - 0.13 11.7 0.0 3.2 7.2 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Peptidase_C12 PF01088.16 KII84171.1 - 3.2e-50 170.3 0.0 6.9e-39 133.2 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 KII84171.1 - 0.039 14.5 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Pkinase PF00069.20 KII84173.1 - 0.00038 19.6 0.0 0.0005 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84173.1 - 0.025 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FHA PF00498.21 KII84176.1 - 1.6e-15 56.9 0.0 3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Baculo_PEP_C PF04513.7 KII84176.1 - 0.0061 16.3 6.4 0.57 10.0 2.6 3.1 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KII84176.1 - 0.018 14.8 9.6 0.046 13.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KII84176.1 - 0.09 11.9 2.0 0.62 9.1 0.3 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF3829 PF12889.2 KII84176.1 - 0.13 11.4 4.6 0.72 8.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) BLOC1_2 PF10046.4 KII84176.1 - 0.13 12.3 8.5 1 9.5 0.9 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 KII84176.1 - 0.35 11.2 13.8 1.4 9.2 2.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 KII84176.1 - 0.72 9.9 7.8 7 6.7 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 KII84176.1 - 1.3 8.9 14.2 1.1 9.1 0.6 4.0 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 EHN PF06441.7 KII84176.1 - 3 7.7 7.8 2.1 8.3 1.2 2.5 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Pkinase PF00069.20 KII84179.1 - 3.2e-06 26.4 0.0 5.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84179.1 - 0.0024 17.0 0.0 0.0046 16.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase F-box-like PF12937.2 KII84180.1 - 4.2e-07 29.5 2.3 9.9e-07 28.3 1.6 1.7 1 0 0 1 1 1 1 F-box-like Erf4 PF10256.4 KII84182.1 - 0.68 9.8 2.9 0.73 9.7 0.5 2.2 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family ADH_zinc_N PF00107.21 KII84183.1 - 1.1e-10 41.1 0.1 2.2e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII84183.1 - 1.1e-08 34.8 0.1 4.6e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII84183.1 - 0.011 16.5 0.0 0.045 14.6 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KII84184.1 - 2.7e-11 43.1 0.1 1.1e-10 41.1 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII84184.1 - 7.9e-09 35.2 0.4 4.2e-07 29.7 0.3 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII84184.1 - 0.0019 19.0 0.0 0.0043 17.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ChiC PF06483.6 KII84184.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Chitinase C ADH_zinc_N PF00107.21 KII84185.1 - 7.1e-11 41.7 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII84185.1 - 8.3e-07 28.7 0.2 2.4e-05 24.0 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII84185.1 - 0.00074 20.4 0.0 0.0018 19.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.2 KII84186.1 - 7.4e-06 25.5 5.2 9.8e-06 25.2 2.1 2.4 2 0 0 2 2 2 1 F-box-like Meth_synt_2 PF01717.13 KII84187.1 - 4.9e-16 58.5 0.0 8.1e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KII84187.1 - 0.037 13.2 0.1 1.1 8.4 0.0 2.4 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain NotI PF12183.3 KII84188.1 - 0.049 12.7 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NotI X PF00739.14 KII84188.1 - 0.33 10.8 6.3 5.3 6.9 0.0 2.4 1 1 0 2 2 2 0 Trans-activation protein X RIO1 PF01163.17 KII84189.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KII84189.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KII84190.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII84190.1 - 0.028 14.1 0.2 0.21 11.3 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.13 KII84192.1 - 2.7e-36 123.6 0.1 4.2e-36 123.0 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KII84192.1 - 2.3e-28 98.2 0.4 2.3e-28 98.2 0.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain F-box PF00646.28 KII84193.1 - 0.0024 17.4 0.1 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII84193.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like PhaG_MnhG_YufB PF03334.9 KII84193.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Na+/H+ antiporter subunit Zip PF02535.17 KII84193.1 - 1.5 7.7 7.6 2.3 7.1 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter F-box PF00646.28 KII84195.1 - 0.00068 19.2 0.5 0.0016 18.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII84195.1 - 0.0034 17.0 0.8 0.0072 16.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like Lipase_GDSL_2 PF13472.1 KII84196.1 - 1.8e-05 24.9 0.2 2.5e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII84196.1 - 0.0024 17.7 1.6 0.0037 17.1 1.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Catalase PF00199.14 KII84196.1 - 0.16 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Catalase Aminotran_1_2 PF00155.16 KII84198.1 - 6.7e-28 97.6 0.0 7.9e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DNAPolymera_Pol PF11590.3 KII84198.1 - 0.019 14.6 0.5 0.059 13.0 0.3 1.9 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Beta_elim_lyase PF01212.16 KII84198.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Dynamin_M PF01031.15 KII84199.1 - 4.9e-28 97.7 0.0 1.2e-18 66.9 0.0 2.8 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 KII84199.1 - 3.9e-24 85.3 0.0 9.2e-24 84.1 0.0 1.6 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 KII84199.1 - 1.1e-08 34.8 0.0 2.2e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KII84199.1 - 0.00035 20.5 0.0 0.003 17.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KII84199.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KII84199.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Fungal_trans PF04082.13 KII84200.1 - 3.3e-32 111.4 0.0 7e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84201.1 - 1.3e-09 37.7 7.6 1.8e-09 37.3 5.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.10 KII84201.1 - 1.1 9.3 6.1 2.2 8.3 4.0 1.8 2 1 0 2 2 2 0 Potato type II proteinase inhibitor family Git3 PF11710.3 KII84202.1 - 1.9e-05 24.3 5.5 1.9e-05 24.3 3.8 2.2 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KII84202.1 - 0.00051 19.2 2.3 0.00051 19.2 1.6 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KII84202.1 - 0.005 16.5 0.1 0.021 14.5 0.1 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 KII84202.1 - 7.2 5.4 13.0 5 5.9 7.2 2.1 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor TarH PF02203.10 KII84203.1 - 0.24 11.2 1.2 0.47 10.2 0.8 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF3278 PF11683.3 KII84203.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) Dynamin_M PF01031.15 KII84204.1 - 1.1e-26 93.3 0.0 1.9e-18 66.2 0.0 2.4 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 KII84204.1 - 6.9e-25 87.8 0.0 2.6e-24 85.9 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 KII84204.1 - 3.2e-09 36.5 0.0 1.1e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KII84204.1 - 0.00036 20.4 0.0 0.0037 17.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KII84204.1 - 0.049 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KII84204.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SET PF00856.23 KII84205.1 - 0.0024 18.2 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.13 KII84206.1 - 2.9e-29 101.7 0.3 2.9e-29 101.7 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84206.1 - 6.8e-10 38.6 6.6 1.4e-09 37.7 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KII84207.1 - 3.5e-37 128.1 0.0 8.3e-17 61.2 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 KII84207.1 - 1.7e-35 122.4 0.3 2.7e-35 121.7 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KII84207.1 - 4.8e-06 25.6 1.1 3.1e-05 23.0 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KII84207.1 - 1.5e-05 24.9 0.9 3.4e-05 23.7 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII84207.1 - 0.00054 18.9 4.4 0.00061 18.7 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII84207.1 - 0.0015 17.4 0.1 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KII84207.1 - 0.0038 17.3 0.5 0.13 12.3 0.1 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII84207.1 - 0.0052 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KII84207.1 - 0.037 13.0 0.2 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KII84207.1 - 0.04 13.0 0.2 0.081 12.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KII84207.1 - 0.044 13.5 0.1 0.55 9.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 KII84208.1 - 5.3e-27 94.3 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84208.1 - 8.6e-07 28.7 7.1 1.6e-06 27.8 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAP_C PF03943.8 KII84209.1 - 0.13 11.6 0.2 0.24 10.8 0.2 1.3 1 0 0 1 1 1 0 TAP C-terminal domain EB1_binding PF05937.6 KII84210.1 - 0.094 13.0 3.0 0.16 12.3 2.1 1.3 1 0 0 1 1 1 0 EB-1 Binding Domain IncA PF04156.9 KII84211.1 - 0.5 9.9 8.3 1.7 8.1 4.8 2.3 2 1 0 2 2 2 0 IncA protein Aconitase PF00330.15 KII84212.1 - 6.2e-178 592.0 0.2 1.3e-177 590.9 0.1 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KII84212.1 - 2e-44 150.8 0.0 3.5e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DNA_RNApol_7kD PF03604.8 KII84218.1 - 1.2 8.6 6.4 2.9 7.4 4.5 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 KII84220.1 - 0.045 13.4 0.6 0.079 12.6 0.4 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Sulfate_transp PF00916.15 KII84221.1 - 2.1e-56 191.0 10.3 2.1e-56 191.0 7.2 1.5 1 1 1 2 2 2 1 Sulfate transporter family STAS PF01740.16 KII84221.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Myc_target_1 PF15179.1 KII84221.1 - 0.084 12.4 1.1 0.18 11.3 0.7 1.5 1 0 0 1 1 1 0 Myc target protein 1 gp32 PF08804.5 KII84228.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 gp32 DNA binding protein like HUN PF08729.5 KII84232.1 - 7.2e-10 38.5 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 KII84232.1 - 1.6e-08 34.5 0.0 5.6e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Ubinuclein conserved middle domain DUF3097 PF11296.3 KII84232.1 - 0.066 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) GED PF02212.13 KII84233.1 - 0.0045 16.8 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain ADH_zinc_N PF00107.21 KII84236.1 - 1.3e-11 44.1 0.0 3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII84236.1 - 1e-08 34.8 0.4 1.9e-07 30.8 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glycos_transf_1 PF00534.15 KII84236.1 - 0.04 13.3 0.1 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 ADH_zinc_N_2 PF13602.1 KII84236.1 - 0.043 14.7 0.0 0.58 11.0 0.0 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Rifin_STEVOR PF02009.11 KII84237.1 - 0.16 11.5 0.7 0.3 10.7 0.5 1.4 1 0 0 1 1 1 0 Rifin/stevor family Ctr PF04145.10 KII84237.1 - 1.5 8.9 2.7 2.4 8.1 0.0 2.5 2 1 0 2 2 2 0 Ctr copper transporter family TFIIA PF03153.8 KII84237.1 - 7.9 6.2 12.2 1 9.1 4.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Xpo1 PF08389.7 KII84238.1 - 7.3e-16 58.4 0.5 7.6e-13 48.6 0.1 4.1 5 0 0 5 5 5 2 Exportin 1-like protein IBN_N PF03810.14 KII84238.1 - 0.0031 17.4 0.0 0.0086 15.9 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.6 KII84238.1 - 0.04 12.8 0.3 0.29 10.0 0.0 2.4 2 1 1 3 3 3 0 CRM1 C terminal F-box PF00646.28 KII84240.1 - 0.00014 21.4 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain Afi1 PF07792.7 KII84243.1 - 6.9e-40 136.3 0.0 1.6e-39 135.2 0.0 1.6 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KII84243.1 - 1.8e-29 101.7 0.0 3.7e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KII84243.1 - 7e-05 21.4 0.0 0.033 12.6 0.0 2.9 3 1 1 4 4 4 2 Transport protein Avl9 Cytochrom_B561 PF03188.11 KII84247.1 - 5.7e-11 42.3 9.3 5.7e-11 42.3 6.4 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF1469 PF07332.6 KII84247.1 - 0.00092 18.9 3.1 0.00092 18.9 2.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1469) DUF2427 PF10348.4 KII84247.1 - 0.0091 15.5 4.8 0.0091 15.5 3.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) 7tm_1 PF00001.16 KII84247.1 - 0.39 9.7 4.7 0.21 10.6 0.8 2.2 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) IncA PF04156.9 KII84247.1 - 1.8 8.1 7.3 4.5 6.8 0.2 2.9 3 0 0 3 3 3 0 IncA protein DUF4149 PF13664.1 KII84247.1 - 4.3 7.4 11.9 0.31 11.1 3.4 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Coatomer_WDAD PF04053.9 KII84248.1 - 2.9e-140 467.9 0.0 7.7e-140 466.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KII84248.1 - 1.3e-98 330.3 0.0 1.9e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KII84248.1 - 1.2e-60 199.3 5.9 1.2e-10 40.8 0.1 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat TPR_14 PF13428.1 KII84248.1 - 0.021 15.4 6.8 12 6.8 0.5 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 KII84248.1 - 0.021 14.3 0.4 0.058 12.9 0.1 1.8 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.3 KII84248.1 - 0.044 11.9 0.6 0.72 7.9 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 TPR_16 PF13432.1 KII84248.1 - 6 7.6 14.5 4.5 8.0 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat HH_signal PF01085.13 KII84249.1 - 0.059 12.9 0.1 0.09 12.3 0.1 1.3 1 1 0 1 1 1 0 Hedgehog amino-terminal signalling domain TarH PF02203.10 KII84249.1 - 0.096 12.5 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue RNase_H PF00075.19 KII84250.1 - 2.5e-25 89.3 0.0 7.2e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 KII84250.1 - 0.0014 18.8 1.1 0.0043 17.3 0.8 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 KII84251.1 - 0.00021 20.7 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 KII84252.1 - 7.6e-08 31.9 0.8 1.8e-07 30.8 0.0 1.9 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KII84252.1 - 2e-05 24.6 0.1 2.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XPG_I PF00867.13 KII84254.1 - 7e-16 58.0 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KII84254.1 - 1.2e-05 25.4 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KII84254.1 - 0.00021 21.4 0.0 0.0012 19.0 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold CENP-F_leu_zip PF10473.4 KII84255.1 - 0.0097 15.7 8.0 0.0097 15.7 5.5 6.7 2 1 6 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KII84255.1 - 2.8 7.5 88.9 0.28 10.7 4.8 6.7 2 1 3 6 6 6 0 IncA protein Ferritin PF00210.19 KII84256.1 - 0.00042 20.0 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain zf-C2H2_jaz PF12171.3 KII84257.1 - 5.8e-06 26.2 5.4 0.021 14.9 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII84257.1 - 0.0011 19.0 5.4 0.12 12.6 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KII84257.1 - 0.052 13.8 21.1 0.4 11.1 3.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type LSM PF01423.17 KII84259.1 - 3.3e-18 64.9 1.1 4.3e-18 64.6 0.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KII84259.1 - 0.021 14.7 0.1 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 KII84259.1 - 0.036 13.7 1.1 0.049 13.3 0.2 1.6 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Gemin7 PF11095.3 KII84259.1 - 0.072 12.8 0.1 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) API5 PF05918.6 KII84259.1 - 5.3 5.4 9.1 6.7 5.0 6.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) tRNA-synt_2 PF00152.15 KII84260.1 - 6e-72 242.2 0.0 7.3e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KII84260.1 - 4.6e-12 45.6 0.0 7.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 KII84260.1 - 0.021 14.2 0.1 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like zf-MYND PF01753.13 KII84262.1 - 8.7e-08 31.9 13.3 2.6e-07 30.3 9.2 1.9 1 1 0 1 1 1 1 MYND finger Toxin_27 PF08099.6 KII84262.1 - 0.0029 17.4 1.6 0.0029 17.4 1.1 2.5 3 0 0 3 3 3 1 Scorpion calcine family Methyltransf_23 PF13489.1 KII84263.1 - 6.6e-18 64.9 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII84263.1 - 1.5e-14 53.8 0.0 4.8e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII84263.1 - 3.3e-10 40.3 0.0 5.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII84263.1 - 2e-09 37.7 0.0 3.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII84263.1 - 2.4e-08 34.5 0.0 6.8e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KII84263.1 - 6.5e-06 25.5 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KII84263.1 - 7.4e-05 21.8 0.0 0.00019 20.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.7 KII84263.1 - 0.0002 20.9 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 KII84263.1 - 0.00088 19.5 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII84263.1 - 0.0016 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KII84263.1 - 0.0026 17.1 0.0 0.0076 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain GidB PF02527.10 KII84263.1 - 0.0033 16.5 0.0 0.01 14.9 0.0 1.7 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.6 KII84263.1 - 0.0039 15.9 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 KII84263.1 - 0.0049 16.4 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KII84263.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KII84263.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.13 KII84263.1 - 0.018 14.3 0.0 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KII84263.1 - 0.027 14.4 0.0 0.092 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KII84263.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.7 KII84263.1 - 0.051 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 KII84263.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PX PF00787.19 KII84264.1 - 1e-18 67.1 0.0 3.1e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 KII84264.1 - 9.1e-14 51.2 0.2 2.5e-13 49.8 0.4 1.5 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_9 PF14604.1 KII84264.1 - 2.7e-07 30.0 0.0 6.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII84264.1 - 2.9e-06 26.5 0.0 5.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII84264.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Dimer_Tnp_hAT PF05699.9 KII84265.1 - 0.033 13.7 0.0 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region TFIIA PF03153.8 KII84265.1 - 0.13 12.1 4.3 0.07 13.0 0.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 KII84265.1 - 0.26 10.4 8.1 0.18 10.9 2.6 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Homeobox PF00046.24 KII84266.1 - 9.4e-14 50.7 5.0 9.4e-14 50.7 3.5 2.2 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KII84266.1 - 9e-06 25.2 0.2 2.4e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KII84266.1 - 0.053 12.5 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Med3 PF11593.3 KII84266.1 - 2.8 7.0 5.9 3.6 6.7 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rep_fac-A_3 PF08661.6 KII84267.1 - 1.4e-20 73.2 0.3 1.4e-20 73.1 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 SCP2 PF02036.12 KII84267.1 - 0.14 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 SCP-2 sterol transfer family Aldo_ket_red PF00248.16 KII84268.1 - 1.7e-48 164.8 0.0 2e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KII84269.1 - 6.6e-22 78.1 0.0 8.5e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII84269.1 - 1.8e-14 54.0 0.0 2.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII84269.1 - 1.2e-08 34.7 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII84269.1 - 0.00074 19.5 0.1 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding DUF3455 PF11937.3 KII84270.1 - 3.9e-24 85.5 1.0 5e-24 85.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Mlp PF03304.8 KII84271.1 - 0.0063 16.5 1.2 3.2 7.7 0.2 2.2 2 0 0 2 2 2 2 Mlp lipoprotein family GldM_N PF12081.3 KII84271.1 - 0.06 12.8 5.9 0.96 8.9 2.0 2.1 1 1 1 2 2 2 0 GldM N-terminal domain Syntaxin_2 PF14523.1 KII84271.1 - 0.23 11.4 2.3 0.69 9.9 0.2 2.2 1 1 1 2 2 2 0 Syntaxin-like protein PhoU PF01895.14 KII84271.1 - 0.28 11.6 2.7 0.75 10.2 1.9 2.0 1 1 0 1 1 1 0 PhoU domain DUF1539 PF07560.6 KII84271.1 - 0.34 10.7 1.5 0.44 10.4 0.6 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF2570 PF10828.3 KII84271.1 - 5.5 6.6 6.4 10 5.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) RRN3 PF05327.6 KII84271.1 - 5.6 4.9 7.2 2.2 6.2 3.4 1.4 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LTXXQ PF07813.7 KII84271.1 - 6.9 7.2 12.7 1.3 9.5 3.9 2.2 1 1 0 2 2 2 0 LTXXQ motif family protein TBCA PF02970.11 KII84271.1 - 7.6 6.6 14.8 1.9 8.5 5.1 2.7 1 1 2 3 3 3 0 Tubulin binding cofactor A PIG-L PF02585.12 KII84272.1 - 5e-23 82.0 0.2 7.4e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.5 KII84273.1 - 1.5e-07 31.9 0.0 2.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ank_2 PF12796.2 KII84274.1 - 4.2e-22 78.2 0.4 1.4e-12 47.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII84274.1 - 1.9e-16 60.0 0.0 2e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII84274.1 - 1e-13 51.0 0.0 1.4e-07 31.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KII84274.1 - 1.6e-13 49.7 0.4 0.00065 19.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat DnaJ PF00226.26 KII84274.1 - 1.6e-13 50.1 0.0 2.2e-11 43.3 0.0 3.2 2 0 0 2 2 2 1 DnaJ domain Ank_3 PF13606.1 KII84274.1 - 5.1e-10 38.5 0.1 0.011 15.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat zf-CCCH PF00642.19 KII84274.1 - 0.00021 20.8 4.0 0.0004 19.9 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_6 PF13516.1 KII84275.1 - 6.7e-08 31.8 5.4 0.39 10.9 0.0 5.7 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.2 KII84275.1 - 0.057 13.1 0.4 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 KII84275.1 - 0.072 12.7 0.4 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 F-box domain FERM_N PF09379.5 KII84275.1 - 0.1 12.6 0.1 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain LRR_7 PF13504.1 KII84275.1 - 7.5 7.2 5.7 30 5.4 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat ABC_tran PF00005.22 KII84276.1 - 1.4e-19 70.7 0.9 3.3e-09 37.1 0.1 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII84276.1 - 2.9e-07 30.7 0.1 0.0059 16.6 0.0 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KII84276.1 - 5e-07 29.1 1.1 0.0034 16.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KII84276.1 - 4e-05 23.4 0.0 0.062 13.2 0.0 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KII84276.1 - 0.00091 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KII84276.1 - 0.0025 18.3 0.0 0.015 15.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 KII84276.1 - 0.0044 16.6 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KII84276.1 - 0.005 16.7 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KII84276.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KII84276.1 - 0.035 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KII84276.1 - 0.036 13.5 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KII84276.1 - 0.055 13.4 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KII84276.1 - 0.063 12.9 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KII84276.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 KII84276.1 - 0.08 11.9 0.4 4.6 6.1 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 KII84276.1 - 0.24 11.6 2.7 0.23 11.7 0.3 1.9 2 0 0 2 2 2 0 AAA domain Rotamase_3 PF13616.1 KII84277.1 - 1.8e-17 63.6 0.1 2.9e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KII84277.1 - 1e-16 61.4 0.6 2e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KII84277.1 - 6.8e-05 23.4 2.1 0.00049 20.7 1.5 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF4638 PF15472.1 KII84277.1 - 1.9 7.9 5.4 2.3 7.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Myb_DNA-binding PF00249.26 KII84278.1 - 2.7e-09 36.9 0.0 5.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII84278.1 - 5.5e-06 26.3 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain HPHLAWLY PF14925.1 KII84278.1 - 0.023 12.7 0.0 0.029 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function BA14K PF07886.6 KII84280.1 - 2.2 8.0 18.3 0.16 11.6 1.2 4.4 2 1 1 4 4 4 0 BA14K-like protein PIG-S PF10510.4 KII84281.1 - 1e-117 393.9 4.1 1.5e-105 353.8 0.7 2.0 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein DUF4087 PF13316.1 KII84282.1 - 0.0017 18.5 0.6 1 9.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4087) CLTH PF10607.4 KII84283.1 - 2.2e-29 101.9 0.0 4.9e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KII84283.1 - 0.0032 17.1 0.3 0.0077 15.9 0.0 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 KII84283.1 - 0.052 12.7 0.1 0.086 12.0 0.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger HlyIII PF03006.15 KII84284.1 - 3.7e-53 180.1 17.7 5e-53 179.7 12.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related p450 PF00067.17 KII84285.1 - 2.9e-32 111.8 0.0 5e-32 111.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Neugrin PF06413.6 KII84286.1 - 2e-13 50.6 1.1 3.2e-13 50.0 0.7 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 KII84286.1 - 5.3e-05 23.2 7.4 0.00011 22.1 5.1 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sigma70_r3 PF04539.11 KII84286.1 - 0.026 14.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 Cofilin_ADF PF00241.15 KII84287.1 - 3.4e-17 62.5 0.0 3.7e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.19 KII84288.1 - 8.5e-14 51.3 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII84288.1 - 1.2e-06 28.5 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII84288.1 - 0.00027 21.0 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII84288.1 - 0.0025 17.9 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII84288.1 - 0.0032 17.3 0.0 0.0071 16.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII84288.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein NAC PF01849.13 KII84289.1 - 5.5e-21 73.8 0.0 8.3e-21 73.2 0.0 1.3 1 0 0 1 1 1 1 NAC domain Glyco_hydro_61 PF03443.9 KII84290.1 - 2.8e-44 151.5 0.0 3.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 KII84291.1 - 0.00044 19.4 0.0 0.041 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MRP-L27 PF09809.4 KII84292.1 - 2.9e-05 23.6 0.1 0.016 14.7 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L27 DUF367 PF04034.8 KII84293.1 - 5.9e-31 106.7 0.0 8.5e-31 106.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KII84293.1 - 6.3e-10 38.4 0.1 1.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Pkinase PF00069.20 KII84295.1 - 2.8e-05 23.4 0.0 0.0086 15.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain LIM PF00412.17 KII84296.1 - 2e-30 104.6 22.5 2.1e-11 43.6 3.3 4.2 4 1 0 4 4 4 4 LIM domain Ribosomal_L37e PF01907.14 KII84296.1 - 0.076 12.8 0.1 0.076 12.8 0.1 3.4 3 0 0 3 3 3 0 Ribosomal protein L37e zf-C2H2 PF00096.21 KII84296.1 - 0.6 10.5 0.2 0.6 10.5 0.2 5.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type DUF3494 PF11999.3 KII84298.1 - 2.2e-54 184.1 22.4 2.2e-54 184.1 15.5 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3494) Kinesin PF00225.18 KII84299.1 - 1.7e-91 306.4 0.0 1.7e-91 306.4 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain TPR_12 PF13424.1 KII84299.1 - 0.0016 18.3 0.1 0.0032 17.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII84299.1 - 0.0032 17.2 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII84299.1 - 0.013 15.2 0.1 0.042 13.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII84299.1 - 0.016 15.7 0.2 0.016 15.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KII84299.1 - 0.031 13.9 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 TPR repeat Serglycin PF04360.7 KII84299.1 - 0.15 11.7 11.4 0.49 10.1 7.9 1.8 1 0 0 1 1 1 0 Serglycin Sel1 PF08238.7 KII84301.1 - 1.1e-18 67.2 14.4 1.6e-07 31.6 0.1 7.1 7 0 0 7 7 7 4 Sel1 repeat TPR_14 PF13428.1 KII84301.1 - 0.0003 21.1 2.2 2.2 9.1 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII84301.1 - 0.0018 17.8 0.3 0.012 15.2 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KII84301.1 - 0.0043 16.5 0.3 0.081 12.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII84301.1 - 0.03 14.2 7.0 0.055 13.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L16 PF00252.13 KII84302.1 - 4.6e-33 113.7 0.1 5.7e-33 113.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAS_9 PF13426.1 KII84303.1 - 1.7e-28 99.0 0.0 2.6e-15 56.6 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 KII84303.1 - 1.1e-17 63.8 0.0 9.2e-05 22.1 0.0 4.0 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 KII84303.1 - 1.2e-11 44.5 0.0 0.00029 20.8 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.6 KII84303.1 - 1.7e-11 44.0 0.0 0.00021 21.3 0.0 4.5 3 1 1 4 4 4 2 PAS fold PAS_11 PF14598.1 KII84303.1 - 2.5e-05 24.1 0.0 0.00018 21.4 0.0 2.3 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.1 KII84303.1 - 0.0044 16.8 0.0 1.1 9.1 0.0 2.8 2 0 0 2 2 2 1 PAS domain Abhydrolase_5 PF12695.2 KII84304.1 - 0.00066 19.4 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KII84304.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FGGY_C PF02782.11 KII84305.1 - 2.6e-48 164.2 0.1 4.3e-48 163.5 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KII84305.1 - 1.5e-21 76.8 0.0 6.1e-21 74.8 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KII84305.1 - 0.0065 15.8 0.1 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 KII84305.1 - 0.028 13.3 0.0 0.078 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) PSD4 PF07631.6 KII84305.1 - 0.087 13.1 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Aldo_ket_red PF00248.16 KII84306.1 - 9.1e-69 231.3 0.0 1e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 KII84306.1 - 0.08 12.8 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family BCDHK_Adom3 PF10436.4 KII84307.1 - 5.2e-67 224.4 0.0 7e-67 224.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KII84307.1 - 1.7e-19 69.5 0.0 5.8e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KII84307.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DivIC PF04977.10 KII84308.1 - 0.17 11.3 0.4 0.37 10.2 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator INTS5_N PF14837.1 KII84310.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Lipase_GDSL_2 PF13472.1 KII84311.1 - 5.7e-09 36.3 0.1 7.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII84311.1 - 4.1e-07 30.0 0.0 6.2e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-RING_2 PF13639.1 KII84312.1 - 2.5e-07 30.4 6.8 2.5e-07 30.4 4.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII84312.1 - 5.2e-07 29.4 2.1 5.2e-07 29.4 1.4 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII84312.1 - 8e-07 28.6 1.8 8e-07 28.6 1.3 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII84312.1 - 1.5e-05 24.9 4.9 1.5e-05 24.9 3.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII84312.1 - 4e-05 23.2 1.1 4e-05 23.2 0.8 2.4 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KII84312.1 - 0.0024 17.4 9.4 0.0056 16.3 4.0 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HAP1_N PF04849.8 KII84312.1 - 0.0049 15.8 0.9 0.0066 15.4 0.6 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF904 PF06005.7 KII84312.1 - 0.017 15.3 4.9 0.75 10.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) zf-CSL PF05207.8 KII84312.1 - 0.04 13.4 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 CSL zinc finger Baculo_IE-1 PF05290.6 KII84312.1 - 0.044 13.5 0.2 0.044 13.5 0.2 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 KII84312.1 - 0.055 13.2 14.7 0.025 14.2 6.3 3.0 2 1 0 2 2 2 0 zinc-RING finger domain TSC22 PF01166.13 KII84312.1 - 0.15 12.0 2.6 0.28 11.1 0.4 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family zf-RING_6 PF14835.1 KII84312.1 - 0.16 11.7 2.6 0.17 11.6 0.3 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-CHY PF05495.7 KII84312.1 - 0.21 11.8 2.5 6.4 7.0 0.1 3.2 3 0 0 3 3 3 0 CHY zinc finger zf-rbx1 PF12678.2 KII84312.1 - 0.26 11.4 8.3 0.39 10.8 2.4 3.3 3 1 0 3 3 3 0 RING-H2 zinc finger FYVE PF01363.16 KII84312.1 - 0.6 10.0 4.5 0.35 10.7 1.0 2.3 2 1 0 2 2 1 0 FYVE zinc finger zf-Apc11 PF12861.2 KII84312.1 - 1 9.2 4.5 0.61 9.9 0.1 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 KII84312.1 - 3.9 7.4 9.3 6.8 6.6 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 KII84312.1 - 7.6 6.1 9.0 11 5.6 0.6 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 BTB PF00651.26 KII84313.1 - 7.9e-11 41.9 0.0 1.1e-09 38.2 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.20 KII84313.1 - 4e-09 36.0 2.0 7.2e-08 32.0 1.0 2.5 2 0 0 2 2 2 1 CAP-Gly domain Uricase PF01014.13 KII84316.1 - 3.3e-68 228.0 0.2 4.9e-40 136.8 0.2 2.4 2 1 0 2 2 2 2 Uricase DUF2066 PF09839.4 KII84316.1 - 0.11 11.5 1.2 0.19 10.8 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) Pkinase PF00069.20 KII84317.1 - 5.4e-73 245.3 0.0 6.4e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84317.1 - 1.2e-32 113.0 0.0 2.5e-32 111.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII84317.1 - 2.1e-05 23.6 0.0 5.6e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KII84317.1 - 0.00019 20.5 0.1 0.00033 19.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII84317.1 - 0.05 13.3 0.8 0.98 9.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-CCCH PF00642.19 KII84318.1 - 3.8e-05 23.2 7.0 0.00031 20.3 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII84318.1 - 0.95 9.5 10.7 0.35 10.9 1.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type EIF_2_alpha PF07541.7 KII84319.1 - 1.3e-36 124.7 0.0 2.6e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KII84319.1 - 5.5e-13 48.8 0.8 1.1e-12 47.8 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain CBF PF03914.12 KII84320.1 - 9.1e-39 132.5 0.9 9.1e-39 132.5 0.6 2.4 3 1 1 4 4 4 1 CBF/Mak21 family EST1_DNA_bind PF10373.4 KII84320.1 - 0.12 11.5 0.2 0.96 8.6 0.0 2.2 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain zf-MYND PF01753.13 KII84321.1 - 5e-09 35.8 10.7 8.9e-09 35.0 7.5 1.4 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.1 KII84323.1 - 3e-15 56.7 0.0 6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII84323.1 - 7.9e-13 48.5 0.0 1.3e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ATP-synt_G PF04718.10 KII84325.1 - 1.7e-20 73.5 0.2 8.6e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Pho88 PF10032.4 KII84326.1 - 2.5e-71 238.8 0.0 2.8e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CitMHS PF03600.11 KII84326.1 - 0.015 13.9 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter TMEMspv1-c74-12 PF11044.3 KII84326.1 - 0.61 9.6 3.9 0.17 11.4 0.4 1.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PH PF00169.24 KII84327.1 - 1.8e-06 28.0 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Ribosomal_60s PF00428.14 KII84327.1 - 0.02 15.2 2.0 0.042 14.2 1.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nnf1 PF03980.9 KII84327.1 - 0.033 14.1 0.9 0.31 11.0 0.2 2.5 2 0 0 2 2 2 0 Nnf1 Carbpep_Y_N PF05388.6 KII84327.1 - 0.083 13.0 1.1 4.7 7.4 0.4 2.4 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF913 PF06025.7 KII84327.1 - 0.2 10.3 3.2 0.16 10.7 0.6 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) NOA36 PF06524.7 KII84327.1 - 0.35 10.0 1.1 0.52 9.5 0.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KII84327.1 - 7.8 6.0 9.3 14 5.2 6.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Pro_CA PF00484.14 KII84329.1 - 1e-34 119.7 0.0 1.3e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF309 PF03745.9 KII84329.1 - 0.17 11.3 0.4 0.88 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Ricin_B_lectin PF00652.17 KII84331.1 - 2.9e-17 62.8 0.0 3.2e-05 23.9 0.0 4.2 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain TFIIA PF03153.8 KII84331.1 - 0.75 9.6 4.8 1 9.1 3.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NST1 PF13945.1 KII84331.1 - 4.6 7.2 6.1 7.1 6.6 4.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF566 PF04484.7 KII84331.1 - 7.4 5.9 16.8 11 5.4 11.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-H2C2_2 PF13465.1 KII84332.1 - 4.1e-07 29.9 14.3 5.9e-07 29.4 1.0 3.8 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII84332.1 - 2.3e-05 24.3 14.5 0.00017 21.6 2.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII84332.1 - 8.5e-05 22.6 14.9 0.00042 20.4 2.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 KII84332.1 - 0.00041 20.4 0.4 0.00097 19.2 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KII84332.1 - 1.3 9.1 7.2 0.77 9.9 0.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Cwf_Cwc_15 PF04889.7 KII84334.1 - 0.012 15.2 7.0 0.012 15.2 4.9 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 KII84334.1 - 0.66 7.8 12.3 0.77 7.5 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 KII84334.1 - 1.5 6.8 3.8 2 6.4 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cpn10 PF00166.16 KII84338.1 - 1.2e-25 89.2 0.0 1.4e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-MYND PF01753.13 KII84339.1 - 2.1e-07 30.6 14.1 3.6e-07 29.9 9.8 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 KII84340.1 - 1.4e-06 27.9 2.8 5.3e-06 26.0 1.0 2.4 2 0 0 2 2 2 1 F-box-like Pro_CA PF00484.14 KII84341.1 - 7.1e-39 133.2 0.0 9.9e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Glutaredoxin PF00462.19 KII84345.1 - 2.4e-14 53.0 0.0 2.2e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KII84345.1 - 6.2e-14 51.5 0.0 1.7e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 KII84345.1 - 0.00031 20.6 0.0 0.0099 15.7 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 KII84345.1 - 0.0099 15.9 0.0 0.79 9.8 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like Ribosomal_60s PF00428.14 KII84345.1 - 0.13 12.7 2.6 0.24 11.8 1.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.2 KII84347.1 - 2.4e-07 30.3 1.2 2.4e-07 30.3 0.8 2.1 2 0 0 2 2 2 1 F-box-like PTPA PF03095.10 KII84348.1 - 5.4e-82 275.3 0.0 6.7e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PhrC_PhrF PF11131.3 KII84348.1 - 0.31 10.6 0.9 0.55 9.8 0.7 1.4 1 0 0 1 1 1 0 Rap-phr extracellular signalling DDE_3 PF13358.1 KII84350.1 - 7.3e-13 48.4 0.2 4.7e-12 45.8 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease Orn_Arg_deC_N PF02784.11 KII84351.1 - 9e-71 237.9 0.0 1.6e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KII84351.1 - 1.5e-31 108.5 0.0 2.6e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KilA-N PF04383.8 KII84353.1 - 0.063 12.9 0.1 0.45 10.1 0.1 2.0 1 1 0 1 1 1 0 KilA-N domain SPX PF03105.14 KII84354.1 - 1.2e-39 136.7 1.9 1.8e-39 136.2 1.3 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KII84354.1 - 6.8e-32 110.9 31.0 9.3e-32 110.4 21.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KII84354.1 - 6.2e-16 57.9 28.5 6e-15 54.6 14.6 2.2 1 1 1 2 2 2 2 Citrate transporter DUF4611 PF15387.1 KII84354.1 - 0.0057 16.7 2.2 0.014 15.5 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) DUF566 PF04484.7 KII84355.1 - 0.14 11.6 3.9 0.18 11.3 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-MYND PF01753.13 KII84356.1 - 2.7e-07 30.3 11.6 2.7e-07 30.3 8.0 2.4 2 0 0 2 2 2 1 MYND finger zf-C3HC4_3 PF13920.1 KII84357.1 - 1.1e-10 40.9 0.7 1.7e-10 40.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII84357.1 - 8.2e-09 35.3 2.3 1.4e-08 34.6 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII84357.1 - 2e-08 33.8 2.0 3.2e-08 33.1 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII84357.1 - 3.2e-08 33.2 2.0 4.8e-08 32.6 1.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII84357.1 - 2.7e-07 30.1 0.1 5.3e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII84357.1 - 0.0034 17.0 1.0 0.011 15.4 0.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KII84357.1 - 0.069 13.0 5.7 0.42 10.5 4.2 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KII84357.1 - 0.14 11.8 1.0 0.33 10.5 0.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 KII84357.1 - 4.8 7.0 6.6 3.5 7.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Isochorismatase PF00857.15 KII84358.1 - 0.0032 17.4 0.0 0.0036 17.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Cytochrom_B561 PF03188.11 KII84359.1 - 2.2e-13 50.1 2.5 4e-13 49.3 0.9 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KII84359.1 - 2.8e-10 40.1 0.5 5.2e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 KII84359.1 - 1.5e-05 24.5 2.3 4.8e-05 22.8 1.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) PepSY_TM_2 PF13703.1 KII84359.1 - 0.0018 18.4 7.9 0.093 12.9 0.0 3.9 3 1 2 5 5 5 2 PepSY-associated TM helix DUF4079 PF13301.1 KII84359.1 - 0.026 14.5 6.7 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.15 KII84359.1 - 0.3 10.4 7.7 2.1 7.7 5.7 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF998 PF06197.8 KII84359.1 - 0.45 9.7 14.5 4.4 6.5 6.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Cytochrom_B_N PF00033.14 KII84359.1 - 1.1 8.5 12.1 18 4.6 8.6 2.6 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Hus1 PF04005.7 KII84360.1 - 2.5e-78 263.0 0.0 2.8e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.11 KII84360.1 - 0.0037 16.0 0.3 0.0072 15.1 0.1 1.6 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Maf PF02545.9 KII84362.1 - 7.1e-41 139.4 0.0 2e-22 79.2 0.0 2.0 2 0 0 2 2 2 2 Maf-like protein ADH_zinc_N PF00107.21 KII84362.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase COPIIcoated_ERV PF07970.7 KII84363.1 - 5e-37 127.6 1.1 7.9e-37 127.0 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KII84363.1 - 3.5e-18 65.3 0.0 6.1e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sdh_cyt PF01127.17 KII84364.1 - 2.8e-25 88.5 1.5 3.5e-25 88.1 1.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pheromone PF08015.6 KII84365.1 - 2.2e-05 25.2 4.0 3.2e-05 24.6 2.8 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone DUF544 PF04424.8 KII84366.1 - 2.8e-16 59.4 0.0 4.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Pheromone PF08015.6 KII84367.1 - 2.5e-06 28.2 2.0 0.04 14.7 0.1 2.5 2 1 0 2 2 2 2 Fungal mating-type pheromone Helicase_C PF00271.26 KII84369.1 - 3.8e-15 55.5 0.0 3.4e-14 52.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII84369.1 - 5.8e-13 48.6 0.0 9.3e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Asp_Glu_race PF01177.17 KII84370.1 - 3.1e-29 102.4 0.1 3.6e-29 102.2 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 KII84370.1 - 0.0054 16.0 0.0 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 AroM protein VWA_2 PF13519.1 KII84370.1 - 0.079 13.0 0.1 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain LRR_6 PF13516.1 KII84371.1 - 5.6e-06 25.8 0.6 1.4 9.2 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.2 KII84371.1 - 0.0069 15.9 0.3 0.043 13.4 0.1 2.4 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) RabGAP-TBC PF00566.13 KII84372.1 - 1.3e-48 165.2 0.0 2.1e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COX6B PF02297.12 KII84373.1 - 1e-20 73.5 3.5 1.3e-20 73.2 2.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KII84373.1 - 0.0021 18.0 0.7 0.0027 17.6 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GHL1-3 PF11308.3 KII84373.1 - 0.0043 16.4 0.1 0.0049 16.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 TPR_11 PF13414.1 KII84376.1 - 2.9e-15 55.6 5.1 8.9e-11 41.2 1.7 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KII84376.1 - 2.9e-08 33.0 8.2 0.0022 17.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KII84376.1 - 3.5e-07 29.5 5.1 0.0044 16.5 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII84376.1 - 3.7e-06 27.4 5.4 0.0036 17.9 0.5 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII84376.1 - 1.7e-05 25.0 0.6 0.00094 19.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII84376.1 - 0.00053 20.3 9.2 0.14 12.8 0.2 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KII84376.1 - 0.021 14.6 0.5 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Phage_P2_GpE PF06528.7 KII84376.1 - 0.037 13.4 0.1 0.12 11.8 0.1 1.9 1 0 0 1 1 1 0 Phage P2 GpE TPR_12 PF13424.1 KII84376.1 - 0.041 13.8 3.8 0.36 10.8 0.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII84376.1 - 0.046 14.1 1.1 0.67 10.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KII84376.1 - 0.059 13.5 3.0 3.5 8.0 0.2 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1629 PF07791.6 KII84376.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) TPR_7 PF13176.1 KII84376.1 - 0.14 12.0 8.9 0.21 11.4 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 KII84376.1 - 0.23 11.7 2.7 2.3 8.5 1.5 2.7 2 1 0 2 2 2 0 Bacterial transcriptional activator domain DDE_3 PF13358.1 KII84378.1 - 7.2e-10 38.7 0.0 7.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KII84379.1 - 0.0055 16.7 0.0 0.0064 16.5 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 KII84379.1 - 0.027 13.9 0.0 0.04 13.4 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 KII84379.1 - 0.042 13.5 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.1 KII84379.1 - 0.05 14.3 0.0 0.077 13.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain CoaE PF01121.15 KII84379.1 - 0.081 12.3 0.0 0.091 12.1 0.0 1.0 1 0 0 1 1 1 0 Dephospho-CoA kinase MFS_1 PF07690.11 KII84380.1 - 7.2e-19 67.7 32.8 1.4e-11 43.7 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII84380.1 - 5e-15 55.0 19.2 1.1e-13 50.5 13.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter PsbN PF02468.10 KII84380.1 - 0.08 12.5 0.3 0.32 10.6 0.2 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) FmdA_AmdA PF03069.10 KII84381.1 - 2e-135 451.2 0.0 2.4e-135 450.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Arrestin_N PF00339.24 KII84382.1 - 0.0012 18.7 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RNase_P_Rpp14 PF01900.14 KII84384.1 - 2.1e-26 91.9 0.0 2.6e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RVT_1 PF00078.22 KII84386.1 - 2e-05 24.0 0.0 4.3e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KII84387.1 - 1.8e-12 47.7 0.0 4.8e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 KII84387.1 - 0.00052 20.2 2.5 0.0017 18.6 1.8 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Aminotran_1_2 PF00155.16 KII84388.1 - 3e-32 111.9 0.0 3.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KII84388.1 - 0.039 12.2 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_cc PF11790.3 KII84389.1 - 1.8e-66 223.9 0.0 2.1e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 KII84389.1 - 0.06 12.1 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 PTCB-BRCT PF12738.2 KII84392.1 - 3.9e-31 106.6 0.0 2.6e-12 46.4 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 KII84392.1 - 1.7e-20 72.9 0.0 1.5e-06 28.2 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain CK_II_beta PF01214.13 KII84393.1 - 2.8e-72 242.1 0.0 3.4e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MBOAT PF03062.14 KII84394.1 - 4.1e-45 154.2 22.7 4.1e-45 154.2 15.7 2.1 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family FAD_binding_3 PF01494.14 KII84395.1 - 1.5e-21 76.8 0.1 4.2e-21 75.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII84395.1 - 1.8e-14 53.4 0.0 3.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII84395.1 - 1.3e-07 31.5 0.0 4e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KII84395.1 - 1.5e-07 30.8 0.2 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KII84395.1 - 1.7e-07 31.3 0.0 4.5e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII84395.1 - 8.2e-07 28.2 0.3 0.071 12.0 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KII84395.1 - 8.9e-07 28.0 0.1 1.6e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KII84395.1 - 6.2e-06 24.9 0.2 1.2e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KII84395.1 - 6e-05 23.3 2.4 0.0013 19.1 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII84395.1 - 9.3e-05 21.6 0.1 0.00015 20.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII84395.1 - 0.00029 20.6 0.4 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KII84395.1 - 0.0006 18.5 0.0 0.048 12.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KII84395.1 - 0.0018 17.8 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KII84395.1 - 0.0025 16.9 0.1 0.026 13.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KII84395.1 - 0.0049 15.7 1.5 0.012 14.4 1.0 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KII84395.1 - 0.01 15.9 0.2 0.027 14.5 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KII84395.1 - 0.019 14.3 0.0 0.57 9.5 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-RVT PF13966.1 KII84396.1 - 0.001 19.3 0.6 0.0014 18.8 0.2 1.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase BNR_2 PF13088.1 KII84398.1 - 0.027 13.7 0.3 0.048 12.9 0.2 1.4 1 0 0 1 1 1 0 BNR repeat-like domain DUF4139 PF13598.1 KII84403.1 - 8e-49 166.6 0.3 7.2e-33 114.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KII84403.1 - 6.3e-19 68.3 2.2 9.4e-18 64.5 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 KII84403.1 - 1.3e-08 35.0 45.3 3.9e-08 33.5 27.3 3.1 3 1 0 3 3 3 1 Nucleoporin FG repeat region TMF_DNA_bd PF12329.3 KII84403.1 - 0.22 11.3 4.8 0.069 12.9 0.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_L30 PF00327.15 KII84404.1 - 1.7e-09 37.1 0.1 2.3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Dmrt1 PF12374.3 KII84404.1 - 3.6 8.0 8.6 1.9 8.8 4.3 1.8 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Abhydrolase_6 PF12697.2 KII84405.1 - 7.9e-26 91.3 0.3 1.3e-25 90.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII84405.1 - 1.9e-09 37.4 0.0 2.9e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KII84405.1 - 3.6e-06 27.3 0.0 6e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KII84405.1 - 8.3e-05 22.2 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 KII84405.1 - 0.0057 16.2 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KII84405.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 KII84405.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 KII84405.1 - 0.16 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) KH_1 PF00013.24 KII84406.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 KH domain Herpes_gE PF02480.11 KII84407.1 - 0.045 12.0 1.0 0.23 9.7 0.7 1.9 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 KII84407.1 - 0.14 11.5 0.0 0.14 11.5 0.0 1.9 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Pentapeptide_4 PF13599.1 KII84409.1 - 0.0053 16.5 0.9 0.014 15.2 0.6 1.7 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 KII84409.1 - 4.2 6.7 10.0 1 8.6 1.9 2.8 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) DUF4388 PF14332.1 KII84410.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) Ada3 PF10198.4 KII84412.1 - 0.02 14.6 0.2 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 GATA PF00320.22 KII84414.1 - 0.14 11.5 1.2 0.35 10.2 0.8 1.7 1 0 0 1 1 1 0 GATA zinc finger TPR_11 PF13414.1 KII84415.1 - 1.5e-24 85.4 1.6 2.7e-12 46.1 0.0 6.9 4 1 3 8 8 8 4 TPR repeat TPR_2 PF07719.12 KII84415.1 - 3.7e-23 79.5 1.1 2e-05 24.1 0.0 8.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 KII84415.1 - 8.7e-23 78.9 0.3 1.1e-08 34.2 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KII84415.1 - 2.3e-22 78.9 4.5 8.3e-08 32.2 0.0 5.9 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KII84415.1 - 6e-19 67.7 2.5 2.7e-11 43.2 0.1 6.9 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII84415.1 - 1.8e-15 55.4 0.0 2.9e-05 23.5 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII84415.1 - 1.9e-14 53.7 0.9 1.3e-05 25.4 0.1 6.0 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KII84415.1 - 2.5e-14 53.4 4.4 5.8e-06 26.8 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII84415.1 - 8.4e-14 50.5 0.3 0.0022 18.0 0.0 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KII84415.1 - 6.2e-13 47.4 0.1 0.0054 16.4 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII84415.1 - 3.9e-10 39.5 8.6 0.0012 19.1 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 KII84415.1 - 9.2e-10 38.1 1.7 0.00092 19.0 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII84415.1 - 2.3e-08 33.9 2.1 0.0074 16.8 0.0 6.1 5 3 2 7 7 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KII84415.1 - 0.00033 20.4 0.1 0.017 14.9 0.0 3.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 KII84415.1 - 0.0018 18.5 0.4 8.4 7.1 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII84415.1 - 0.062 13.1 5.1 0.63 9.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF-1a PF01176.14 KII84416.1 - 1.8e-29 100.9 0.2 2.5e-29 100.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RRM_1 PF00076.17 KII84418.1 - 7e-16 57.6 0.0 1.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII84418.1 - 4.6e-13 48.9 0.0 6.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII84418.1 - 3.7e-09 36.2 0.0 6.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VPS28 PF03997.7 KII84418.1 - 0.057 13.0 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 VPS28 protein Myco_arth_vir_N PF09610.5 KII84419.1 - 0.73 9.8 2.2 1.8 8.5 0.5 2.2 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Sugar_tr PF00083.19 KII84420.1 - 6e-50 170.1 21.5 7.8e-50 169.7 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII84420.1 - 2.5e-24 85.6 32.5 1.2e-23 83.4 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MerE PF05052.7 KII84420.1 - 0.8 9.7 5.8 36 4.4 0.0 3.6 3 0 0 3 3 3 0 MerE protein Fungal_trans PF04082.13 KII84421.1 - 2.7e-10 39.5 0.1 1.1e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84421.1 - 0.02 14.7 12.9 0.034 14.0 8.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Maf1 PF09174.5 KII84422.1 - 1.3e-37 129.3 0.1 8.5e-31 107.1 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator p450 PF00067.17 KII84423.1 - 4.6e-70 236.4 0.0 5.4e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Complex1_LYR PF05347.10 KII84424.1 - 1.6e-13 50.2 1.5 1.9e-13 49.9 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII84424.1 - 1.7e-12 47.3 0.6 2.5e-12 46.8 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KII84424.1 - 0.00033 21.0 0.1 0.00042 20.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like SCP2 PF02036.12 KII84425.1 - 7.6e-24 83.9 0.9 9.5e-24 83.6 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KII84425.1 - 1.8e-05 24.7 0.6 2.3e-05 24.3 0.4 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Pab87_oct PF13969.1 KII84425.1 - 0.078 13.0 0.1 0.93 9.6 0.1 2.0 2 0 0 2 2 2 0 Pab87 octamerisation domain Dynamin_N PF00350.18 KII84426.1 - 2.6e-41 141.2 0.0 4.9e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KII84426.1 - 2.1e-09 36.6 0.0 2.3e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region AAA_16 PF13191.1 KII84426.1 - 0.00064 19.7 0.2 0.68 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 KII84426.1 - 0.0027 18.1 0.0 0.0092 16.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KII84426.1 - 0.0037 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Biopterin_H PF00351.16 KII84426.1 - 0.093 11.4 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase DHDPS PF00701.17 KII84427.1 - 2.5e-45 154.3 0.0 3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KII84427.1 - 0.0044 16.2 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Med22 PF06179.7 KII84428.1 - 1.5e-14 53.9 0.8 2.1e-14 53.4 0.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.7 KII84428.1 - 0.073 13.3 1.0 1 9.6 0.1 2.2 1 1 1 2 2 2 0 PMC2NT (NUC016) domain WD40 PF00400.27 KII84429.1 - 0.00012 21.8 0.2 0.024 14.4 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 KII84430.1 - 3.1e-12 46.3 0.0 5.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII84430.1 - 3.4e-10 39.9 0.0 1.8e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII84430.1 - 1.8e-08 34.4 0.0 2.4e-06 27.6 0.0 2.2 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII84430.1 - 2.8e-05 23.9 0.5 0.0017 18.2 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII84430.1 - 0.049 13.3 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.20 KII84431.1 - 3.5e-06 26.3 0.0 1.5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84431.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.2 KII84432.1 - 3.5e-09 36.2 0.5 3.5e-09 36.2 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII84432.1 - 0.07 12.8 4.0 3.7 7.3 1.4 3.3 3 0 0 3 3 3 0 F-box domain DUF1748 PF08520.5 KII84433.1 - 7.9e-22 76.6 0.0 8.7e-22 76.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Serinc PF03348.10 KII84434.1 - 4.4e-158 526.4 5.4 5.3e-158 526.2 3.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3661 PF12400.3 KII84434.1 - 0.012 15.7 2.1 0.012 15.7 1.5 2.5 2 0 0 2 2 2 0 Vaculolar membrane protein DUF2621 PF11084.3 KII84434.1 - 1.6 8.4 4.0 3.6 7.2 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) F-box-like PF12937.2 KII84436.1 - 2.9e-07 30.0 0.8 6.8e-07 28.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII84436.1 - 0.092 12.3 0.0 1.4 8.6 0.0 2.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.18 KII84437.1 - 8.3e-14 52.1 0.1 4.8e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family CBM_5_12 PF02839.9 KII84437.1 - 3e-08 33.1 10.6 8.8e-08 31.6 6.0 2.6 2 0 0 2 2 2 1 Carbohydrate binding domain DUF1777 PF08648.7 KII84437.1 - 0.97 9.1 20.7 0.019 14.6 4.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Rad51 PF08423.6 KII84438.1 - 4e-15 55.4 0.0 6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KII84438.1 - 9.5e-08 31.4 0.1 1.6e-07 30.6 0.1 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KII84438.1 - 2.2e-07 30.2 0.0 5.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 KII84438.1 - 2.4e-07 30.3 0.0 1.5e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 KII84438.1 - 0.00011 21.1 0.0 0.00042 19.2 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain CobU PF02283.11 KII84438.1 - 0.0026 17.1 0.0 1.1 8.7 0.0 2.5 3 0 0 3 3 3 2 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_16 PF13191.1 KII84438.1 - 0.0042 17.1 0.1 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KII84438.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain Disulph_isomer PF06491.6 KII84438.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase PAXNEB PF05625.6 KII84438.1 - 0.07 11.9 0.2 5.7 5.6 0.0 2.1 2 0 0 2 2 2 0 PAXNEB protein Ribosomal_S10 PF00338.17 KII84439.1 - 4.1e-31 106.6 0.6 4.8e-31 106.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.8 KII84440.1 - 5.4e-58 196.7 0.7 6.9e-58 196.3 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Aminotran_1_2 PF00155.16 KII84441.1 - 2.7e-23 82.5 0.0 3.1e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KII84441.1 - 1.7e-09 36.7 0.0 2.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase F-box-like PF12937.2 KII84442.1 - 1.5e-09 37.3 3.1 4.8e-09 35.8 2.2 2.0 1 0 0 1 1 1 1 F-box-like ARID PF01388.16 KII84443.1 - 9.7e-10 38.1 0.0 1.9e-08 34.0 0.0 3.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain F-box-like PF12937.2 KII84445.1 - 1.7e-07 30.8 0.0 3.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII84445.1 - 0.0083 15.7 0.1 3.2 7.4 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) DUF1515 PF07439.6 KII84445.1 - 0.037 13.8 0.4 0.091 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) SNARE_assoc PF09335.6 KII84446.1 - 2.8e-12 46.9 5.7 2.8e-12 46.9 3.9 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein TctB PF07331.6 KII84446.1 - 0.019 14.5 0.4 0.019 14.5 0.3 2.5 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Colicin PF01024.14 KII84446.1 - 0.037 13.5 0.2 0.037 13.5 0.1 1.5 2 0 0 2 2 2 0 Colicin pore forming domain Fungal_trans PF04082.13 KII84447.1 - 1.9e-17 63.0 0.0 2.7e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 KII84448.1 - 1.3e-17 63.2 0.6 3.2e-17 62.0 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.14 KII84449.1 - 2.5e-38 131.3 0.0 3.2e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KII84449.1 - 0.0012 18.5 0.0 0.0036 17.0 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 KII84449.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Pox_A32 PF04665.7 KII84449.1 - 0.095 11.9 0.2 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.1 KII84449.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DnaJ PF00226.26 KII84450.1 - 1.7e-25 88.5 0.9 3.3e-25 87.6 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KII84450.1 - 2.9e-06 27.2 0.0 7.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII84450.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KII84450.1 - 0.039 14.2 0.6 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger MBF1 PF08523.5 KII84450.1 - 0.053 13.5 0.4 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Multiprotein bridging factor 1 LTXXQ PF07813.7 KII84450.1 - 0.72 10.3 0.1 0.72 10.3 0.1 2.4 2 1 0 2 2 2 0 LTXXQ motif family protein Prp18 PF02840.10 KII84451.1 - 9e-59 197.4 0.2 9e-59 197.4 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KII84451.1 - 1.1e-11 43.8 4.3 2.3e-11 42.7 3.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pinin_SDK_memA PF04696.8 KII84451.1 - 7.3 6.2 19.0 0.73 9.4 5.1 3.3 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region COX6B PF02297.12 KII84452.1 - 9.2e-20 70.4 7.0 1.1e-19 70.2 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KII84452.1 - 0.00038 20.2 0.9 0.0008 19.2 0.6 1.6 1 1 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 KII84452.1 - 1.9 8.3 7.9 8.4 6.3 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) zf-Tim10_DDP PF02953.10 KII84453.1 - 4.3e-20 70.7 1.0 5.5e-20 70.4 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FANCI_S3 PF14677.1 KII84453.1 - 0.033 13.5 0.3 0.063 12.6 0.2 1.5 1 1 0 1 1 1 0 FANCI solenoid 3 DUF725 PF05267.7 KII84453.1 - 0.047 13.6 0.9 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF725) Cytomega_TRL10 PF06084.6 KII84453.1 - 0.075 12.8 0.6 0.094 12.5 0.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Beta-lactamase PF00144.19 KII84454.1 - 1e-39 136.5 0.0 2.7e-39 135.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase APC_crr PF05923.7 KII84455.1 - 0.3 10.7 6.8 0.097 12.3 2.2 2.2 2 0 0 2 2 2 0 APC cysteine-rich region Adaptin_N PF01602.15 KII84456.1 - 2e-115 386.1 1.6 2.9e-115 385.5 1.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KII84456.1 - 1.6e-07 31.5 4.5 0.087 13.1 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KII84456.1 - 0.00028 20.6 3.1 3 8.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HTH_36 PF13730.1 KII84456.1 - 0.059 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HEAT_EZ PF13513.1 KII84456.1 - 0.081 13.4 4.3 5.5 7.6 0.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat CENP-T PF15511.1 KII84456.1 - 0.96 8.6 19.6 1.6 7.9 13.6 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 KII84456.1 - 1 7.7 23.8 1.6 7.1 16.5 1.2 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 KII84456.1 - 3.8 5.2 12.1 6 4.5 8.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.7 KII84456.1 - 3.9 6.5 27.1 7.7 5.5 18.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Homeobox PF00046.24 KII84457.1 - 8.7e-19 66.8 1.2 1.6e-18 66.0 0.8 1.5 1 0 0 1 1 1 1 Homeobox domain FlhE PF06366.8 KII84457.1 - 0.039 13.8 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlhE U1snRNP70_N PF12220.3 KII84458.1 - 2.4e-16 59.8 0.7 4.6e-16 58.9 0.5 1.5 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KII84458.1 - 4.8e-16 58.1 0.0 8.5e-16 57.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII84458.1 - 2.3e-12 46.6 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII84458.1 - 1.2e-06 28.2 0.1 3.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KII84459.1 - 0.0022 18.1 0.1 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KII84459.1 - 0.045 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Chorismate_bind PF00425.13 KII84459.1 - 0.37 10.0 4.7 0.096 11.9 0.8 1.7 2 0 0 2 2 2 0 chorismate binding enzyme CAF-1_p150 PF11600.3 KII84459.1 - 0.78 9.0 22.8 1.5 8.1 0.7 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NAPRTase PF04095.11 KII84461.1 - 4.6e-60 202.9 0.0 6.9e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RNase_PH PF01138.16 KII84462.1 - 2.4e-34 118.5 0.2 4.7e-34 117.5 0.1 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KII84462.1 - 0.014 15.3 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.12 KII84463.1 - 9e-55 184.7 0.0 1.1e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII84463.1 - 2.2e-06 28.2 0.0 3.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII84463.1 - 2.1e-05 24.5 0.0 3.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII84463.1 - 0.0018 18.5 0.0 0.0044 17.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII84463.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KII84463.1 - 0.07 13.6 0.0 0.36 11.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KII84463.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 KII84463.1 - 0.095 12.0 0.0 0.4 10.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Citrate_synt PF00285.16 KII84464.1 - 1.8e-98 329.5 0.0 2.1e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KII84464.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone gag_pre-integrs PF13976.1 KII84467.1 - 1.2e-06 27.9 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain FeoC PF09012.5 KII84467.1 - 0.042 13.5 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator Methyltransf_23 PF13489.1 KII84471.1 - 1e-13 51.3 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII84471.1 - 1.7e-11 44.4 0.0 3.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII84471.1 - 9.9e-09 34.9 0.0 6e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII84471.1 - 4.3e-07 30.3 0.0 1.9e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII84471.1 - 4.7e-07 30.1 0.0 8.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII84471.1 - 6.3e-06 25.4 0.0 3.7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KII84471.1 - 1.7e-05 25.3 0.0 8.4e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KII84471.1 - 3.5e-05 23.4 0.0 9.5e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_29 PF03141.11 KII84471.1 - 6e-05 21.5 0.0 0.00041 18.8 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 KII84471.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KII84471.1 - 0.00051 20.0 0.1 0.0016 18.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KII84471.1 - 0.00062 19.0 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KII84471.1 - 0.0025 17.2 0.0 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KII84471.1 - 0.0069 15.4 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KII84471.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 KII84471.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase tRNA-synt_His PF13393.1 KII84473.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Pkinase PF00069.20 KII84474.1 - 1.9e-12 46.9 0.0 2e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84474.1 - 2.9e-11 42.9 0.0 3.3e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII84474.1 - 0.0065 15.4 0.0 0.0065 15.4 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pirin PF02678.11 KII84475.1 - 0.37 10.6 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Pirin Neisseria_TspB PF05616.8 KII84476.1 - 2.1 6.6 5.0 2.4 6.4 3.5 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein UPF0139 PF03669.8 KII84477.1 - 0.15 11.5 0.4 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Ribonuc_red_sm PF00268.16 KII84479.1 - 1.1e-71 241.0 0.1 1.4e-71 240.8 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HWE_HK PF07536.9 KII84479.1 - 0.017 15.5 0.9 0.035 14.5 0.6 1.6 1 1 0 1 1 1 0 HWE histidine kinase Ribonuc_red_sm PF00268.16 KII84480.1 - 1.6e-90 302.9 0.4 1.6e-89 299.6 0.3 1.9 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain Fungal_trans PF04082.13 KII84482.1 - 9.2e-22 77.1 0.3 1.1e-21 76.9 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain SDA1 PF05285.7 KII84484.1 - 0.00024 20.4 14.0 0.00027 20.3 9.7 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 KII84484.1 - 0.00039 18.5 21.0 0.00055 18.0 14.6 1.2 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 KII84484.1 - 0.0015 17.6 9.6 0.0018 17.3 6.7 1.3 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.9 KII84484.1 - 1.4 6.9 16.4 1.7 6.6 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 KII84484.1 - 2.9 6.0 4.7 3 5.9 3.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CENP-T PF15511.1 KII84484.1 - 3.6 6.7 17.5 0.32 10.2 8.4 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T VitD-bind_III PF09164.5 KII84486.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF2483 PF10656.4 KII84488.1 - 0.42 10.7 1.4 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2483) Peptidase_C48 PF02902.14 KII84489.1 - 2.3e-11 43.7 0.0 4.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain F-box-like PF12937.2 KII84490.1 - 1.1e-09 37.8 0.4 2e-09 37.0 0.3 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KII84490.1 - 0.0018 17.8 1.1 0.079 12.6 0.1 2.3 2 0 0 2 2 2 2 F-box domain DUF3505 PF12013.3 KII84491.1 - 1.5e-08 34.8 2.9 3.7e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Cas_Cas6 PF01881.11 KII84491.1 - 0.019 15.2 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas6 ATP1G1_PLM_MAT8 PF02038.11 KII84491.1 - 0.05 12.6 0.4 0.1 11.5 0.3 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Mito_fiss_reg PF05308.6 KII84493.1 - 0.098 12.0 2.4 0.12 11.7 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator RNA_pol_L PF01193.19 KII84494.1 - 0.076 12.1 0.4 0.2 10.8 0.3 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF35_N PF12172.3 KII84495.1 - 0.39 10.6 3.9 0.53 10.2 0.2 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Retrotrans_gag PF03732.12 KII84496.1 - 0.0024 17.9 0.2 0.0038 17.2 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Alpha_kinase PF02816.13 KII84498.1 - 2e-14 53.6 0.0 3.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family TF_AP-2 PF03299.9 KII84499.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 Ter PF05472.6 KII84502.1 - 0.15 11.1 0.0 6.1 5.8 0.0 2.1 2 0 0 2 2 2 0 DNA replication terminus site-binding protein (Ter protein) DUF444 PF04285.7 KII84502.1 - 1.5 7.3 5.3 4.5 5.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF444) RVT_1 PF00078.22 KII84505.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 KII84505.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-C2H2 PF00096.21 KII84506.1 - 0.0011 19.1 0.7 0.0043 17.3 0.5 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KII84506.1 - 0.0092 15.8 0.2 0.023 14.6 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII84506.1 - 0.029 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KII84506.1 - 0.95 9.9 6.1 0.12 12.7 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2515 PF10720.4 KII84510.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) SH3_9 PF14604.1 KII84513.1 - 4.1e-08 32.6 0.0 8.5e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII84513.1 - 1.3e-05 24.4 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII84513.1 - 0.0003 20.2 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain VGCC_beta4Aa_N PF12052.3 KII84513.1 - 0.11 12.4 1.1 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ammonium_transp PF00909.16 KII84515.1 - 3.1e-116 388.1 28.2 3.6e-116 387.9 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family F-box-like PF12937.2 KII84517.1 - 0.013 15.2 1.2 0.019 14.6 0.1 1.9 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KII84518.1 - 2.6e-05 23.8 0.0 7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII84520.1 - 0.00086 18.9 0.6 0.0024 17.5 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII84520.1 - 0.52 9.9 4.1 22 4.8 0.1 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) CobT PF06213.7 KII84522.1 - 0.073 12.1 2.6 0.1 11.7 1.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LRR_8 PF13855.1 KII84522.1 - 0.18 11.5 5.7 0.21 11.3 0.6 3.0 2 1 1 3 3 3 0 Leucine rich repeat Nucleoplasmin PF03066.10 KII84522.1 - 1.5 8.2 8.7 2.4 7.6 6.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KII84522.1 - 9.7 4.5 9.6 13 4.0 6.6 1.1 1 0 0 1 1 1 0 Daxx Family Metallophos PF00149.23 KII84523.1 - 7.5e-11 41.7 0.2 2.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII84523.1 - 2.6e-06 27.3 0.0 6.7e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain N-glycanase_C PF09113.5 KII84523.1 - 0.13 11.9 2.6 0.93 9.1 0.0 2.4 2 0 0 2 2 2 0 Peptide-N-glycosidase F, C terminal FIVAR PF07554.8 KII84523.1 - 0.15 12.3 0.3 0.49 10.6 0.2 1.9 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain AA_permease_2 PF13520.1 KII84524.1 - 6.6e-52 176.4 55.9 8.2e-52 176.1 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII84524.1 - 2.1e-10 39.5 50.9 2.9e-10 39.0 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease O-FucT PF10250.4 KII84525.1 - 7.7e-12 44.9 0.0 4.1e-07 29.4 0.1 3.1 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase eIF3g PF12353.3 KII84526.1 - 1.1e-41 141.6 0.9 1.6e-41 141.2 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KII84526.1 - 2.4e-18 65.4 0.0 3.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII84526.1 - 8.1e-16 57.7 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII84526.1 - 1.4e-08 34.4 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII84526.1 - 0.022 14.6 0.2 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Asp PF00026.18 KII84530.1 - 2.2e-72 244.0 2.0 2.7e-72 243.7 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII84530.1 - 5.9e-09 36.3 3.0 0.0049 17.3 0.1 4.4 3 1 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 KII84530.1 - 4.7e-08 33.1 0.0 2.6e-07 30.7 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal MFS_1 PF07690.11 KII84532.1 - 1.3e-42 145.8 53.1 2.3e-42 144.9 36.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII84532.1 - 1.3e-12 47.0 14.0 1.3e-12 47.0 9.7 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter PCI PF01399.22 KII84533.1 - 2.2e-05 24.7 0.0 5.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Herpes_pp85 PF04637.7 KII84533.1 - 0.033 12.5 0.1 0.13 10.5 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF1631 PF07793.6 KII84533.1 - 0.13 10.3 2.0 0.2 9.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) TPR_8 PF13181.1 KII84533.1 - 0.14 12.0 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KII84533.1 - 0.15 12.0 1.7 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat FMN_red PF03358.10 KII84534.1 - 1.1e-06 28.1 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KII84534.1 - 1.9e-06 27.8 0.0 4.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KII84534.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold F-box-like PF12937.2 KII84536.1 - 8e-06 25.4 1.5 8e-06 25.4 1.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 KII84536.1 - 0.33 10.6 2.2 5.3 6.7 0.0 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.11 KII84538.1 - 7.7e-25 87.3 33.7 7.7e-25 87.3 23.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily GHMP_kinases_C PF08544.8 KII84538.1 - 0.13 12.5 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal NAD_binding_4 PF07993.7 KII84539.1 - 2.1e-40 138.2 0.0 2.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII84539.1 - 4.1e-36 124.2 0.2 9.1e-34 116.5 0.2 2.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KII84539.1 - 4.1e-13 49.3 0.0 6.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KII84539.1 - 8.8e-08 32.3 0.1 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KII84539.1 - 7e-06 26.0 1.1 5.5e-05 23.1 0.7 2.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KII84539.1 - 5.4e-05 22.2 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 KII84539.1 - 0.0042 16.7 0.0 0.0099 15.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KII84539.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KII84539.1 - 0.22 10.1 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F-box-like PF12937.2 KII84540.1 - 7.4e-09 35.1 1.3 2.3e-08 33.6 0.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII84540.1 - 0.096 12.3 6.0 0.32 10.6 1.2 3.1 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KII84541.1 - 1.9e-08 33.8 2.0 2.9e-08 33.3 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII84541.1 - 0.0018 17.8 5.4 0.069 12.8 0.2 4.3 4 1 0 4 4 4 2 F-box domain PGI PF00342.14 KII84543.1 - 1.7e-215 716.0 0.1 2e-215 715.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ras PF00071.17 KII84544.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Ras family Aldose_epim PF01263.15 KII84547.1 - 8.2e-59 199.1 0.4 1.2e-58 198.5 0.3 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Gln-synt_C PF00120.19 KII84548.1 - 1.3e-60 204.7 0.0 2.3e-60 203.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 KII84549.1 - 1.3e-19 70.7 0.4 2e-19 70.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII84549.1 - 1.6e-09 37.6 0.2 2.4e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII84549.1 - 1.1e-08 35.1 0.1 1.7e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII84549.1 - 2.7e-06 27.5 0.3 1.9e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KII84549.1 - 0.0014 18.0 0.1 0.0026 17.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KII84549.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KII84549.1 - 0.082 11.7 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.17 KII84553.1 - 1.9e-19 69.0 0.0 8.2e-12 44.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII84553.1 - 7.1e-19 67.5 0.0 5.6e-10 39.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII84553.1 - 4.3e-08 32.8 0.0 3.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRRSV_2b PF07069.6 KII84555.1 - 0.16 12.3 0.6 0.23 11.7 0.4 1.2 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b NAD_binding_4 PF07993.7 KII84556.1 - 1.3e-31 109.4 0.0 2.1e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII84556.1 - 1.6e-24 86.0 0.0 8.3e-22 77.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KII84556.1 - 1.3e-08 34.5 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII84556.1 - 2e-08 34.4 0.0 4.5e-06 26.7 0.0 3.1 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KII84556.1 - 1.4e-05 25.1 0.0 5.6e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII84556.1 - 0.0012 18.5 0.0 0.0045 16.6 0.0 2.1 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 KII84556.1 - 0.0022 18.2 0.3 0.0091 16.2 0.2 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KII84556.1 - 0.13 10.9 0.0 0.44 9.2 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BTB PF00651.26 KII84559.1 - 1.9e-05 24.5 0.0 7.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain COesterase PF00135.23 KII84560.1 - 5.4e-90 302.6 0.0 6.9e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII84560.1 - 1.1e-07 31.6 0.2 2.5e-07 30.5 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold EKR PF10371.4 KII84560.1 - 0.0017 17.8 0.0 0.004 16.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function Oxidored-like PF09791.4 KII84561.1 - 1.6e-17 62.6 0.1 3.3e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal JAB PF01398.16 KII84562.1 - 5.3e-28 97.0 0.1 9.6e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KII84562.1 - 1.1e-06 28.1 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4404 PF14357.1 KII84562.1 - 0.04 14.3 1.6 0.069 13.5 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Metallophos PF00149.23 KII84564.1 - 1.9e-10 40.4 0.7 2.8e-09 36.6 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII84564.1 - 7.8e-07 29.0 0.0 2.6e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short PF00106.20 KII84565.1 - 1.1e-18 67.6 2.0 1.1e-18 67.6 1.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII84565.1 - 3.5e-07 30.0 0.6 5e-07 29.5 0.4 1.3 1 0 0 1 1 1 1 KR domain AA_permease_2 PF13520.1 KII84566.1 - 7.1e-75 252.1 42.6 9.6e-75 251.7 29.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII84566.1 - 1.6e-17 63.0 32.5 2.5e-17 62.4 22.5 1.2 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.2 KII84567.1 - 8.7e-08 31.7 1.2 2.5e-07 30.3 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII84567.1 - 0.0051 16.4 0.1 0.021 14.4 0.1 2.1 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 KII84567.1 - 0.028 14.1 0.4 1.1 9.0 0.0 3.2 2 1 2 4 4 4 0 Leucine rich repeat p450 PF00067.17 KII84568.1 - 3.1e-82 276.5 0.0 3.7e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KII84570.1 - 1.1e-09 37.9 0.1 2.3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII84570.1 - 0.00019 21.0 0.0 0.00046 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Striatin PF08232.7 KII84570.1 - 0.073 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Striatin family F-box-like PF12937.2 KII84571.1 - 2e-09 37.0 0.1 4e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII84571.1 - 0.0014 18.1 0.0 0.0036 16.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Pro_isomerase PF00160.16 KII84573.1 - 1e-44 152.4 1.6 1.1e-44 152.3 1.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.17 KII84574.1 - 7.6e-77 258.7 0.0 8.5e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C48 PF02902.14 KII84575.1 - 7.3e-09 35.5 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Colicin_C PF12106.3 KII84575.1 - 0.085 12.4 1.6 0.24 11.0 1.1 1.8 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain zf-RING_5 PF14634.1 KII84579.1 - 0.88 9.3 6.2 2.2 8.1 0.2 3.4 3 0 0 3 3 3 0 zinc-RING finger domain DUF2154 PF09922.4 KII84581.1 - 0.043 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Cell wall-active antibiotics response protein (DUF2154) DUF4098 PF13345.1 KII84581.1 - 0.058 13.3 0.1 19 5.3 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4098) p450 PF00067.17 KII84582.1 - 2.1e-81 273.8 0.0 2.5e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Citrate_synt PF00285.16 KII84583.1 - 3.3e-18 65.5 0.0 3.6e-16 58.8 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KII84583.1 - 9.1e-15 54.5 0.1 4.1e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.14 KII84583.1 - 1.3e-11 44.7 0.0 3.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KII84583.1 - 2.9e-05 23.5 0.0 5.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 KII84583.1 - 3e-05 23.6 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribonucleas_3_3 PF14622.1 KII84584.1 - 2e-17 63.3 0.0 1.9e-15 56.9 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease-III-like Rad60-SLD_2 PF13881.1 KII84586.1 - 3.5e-14 52.6 0.0 6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KII84586.1 - 2.2e-05 23.7 0.0 0.00016 21.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin family Ribosomal_L18ae PF01775.12 KII84587.1 - 3.7e-60 201.2 0.4 4.5e-60 200.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Lactonase PF10282.4 KII84588.1 - 1.8e-43 148.9 0.0 2.2e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller RBB1NT PF08169.6 KII84588.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain DUF2264 PF10022.4 KII84589.1 - 2.1e-131 437.9 0.2 2.5e-131 437.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) p450 PF00067.17 KII84590.1 - 5.1e-80 269.2 0.0 6e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4098 PF13345.1 KII84592.1 - 0.00035 20.4 0.2 0.46 10.4 0.0 3.7 2 1 1 3 3 3 3 Domain of unknown function (DUF4098) p450 PF00067.17 KII84593.1 - 5.1e-83 279.1 0.0 6.2e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1275 PF06912.6 KII84596.1 - 2.5e-23 82.3 18.3 3.2e-23 82.0 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 KII84596.1 - 1.7 7.3 27.8 1.2 7.7 10.5 2.5 2 1 0 2 2 2 0 Major Facilitator Superfamily DUF202 PF02656.10 KII84596.1 - 5 7.4 8.3 62 3.9 5.5 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) p450 PF00067.17 KII84597.1 - 3.5e-66 223.6 0.0 4.4e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII84599.1 - 8.5e-69 232.2 0.0 1.1e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII84600.1 - 3e-26 91.9 0.0 3.5e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1679 PF07914.6 KII84602.1 - 0.21 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Amidase PF01425.16 KII84603.1 - 2.9e-87 293.3 0.0 3.5e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Cpl-7 PF08230.6 KII84605.1 - 0.1 12.3 0.0 5.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain HCV_NS1 PF01560.12 KII84606.1 - 0.0088 14.5 0.1 0.0088 14.5 0.1 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 PTS_EIIB PF00367.15 KII84606.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 phosphotransferase system, EIIB Amidase PF01425.16 KII84608.1 - 5.9e-59 200.0 0.2 7.2e-59 199.7 0.1 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 KII84612.1 - 2e-58 198.3 0.2 2.3e-58 198.1 0.1 1.0 1 0 0 1 1 1 1 Amidase RPA_interact_N PF14766.1 KII84613.1 - 0.0046 16.3 2.6 0.0046 16.3 1.8 2.4 2 0 0 2 2 2 2 Replication protein A interacting N-terminal Mob1_phocein PF03637.12 KII84614.1 - 4.1e-25 88.4 0.0 7.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.20 KII84615.1 - 5.5e-39 133.8 0.0 4.4e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII84615.1 - 9.3e-24 83.8 0.0 1.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII84615.1 - 0.0043 16.8 1.2 0.012 15.3 0.8 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family MRP-L20 PF12824.2 KII84615.1 - 4.2 7.3 5.3 3.1 7.7 2.0 1.9 2 1 1 3 3 3 0 Mitochondrial ribosomal protein subunit L20 TFIIA_gamma_N PF02268.11 KII84616.1 - 1.7e-26 91.4 0.2 2.6e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KII84616.1 - 1.2e-22 79.4 0.1 1.7e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2153 PF09921.4 KII84616.1 - 0.098 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) F-box-like PF12937.2 KII84617.1 - 0.00055 19.6 0.9 0.00055 19.6 0.6 2.0 2 0 0 2 2 2 1 F-box-like DUF4164 PF13747.1 KII84617.1 - 0.0061 16.6 0.9 0.011 15.8 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Filament PF00038.16 KII84617.1 - 0.0095 15.4 0.5 0.014 14.8 0.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein Rabaptin PF03528.10 KII84617.1 - 0.02 14.7 0.3 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 Rabaptin DUF869 PF05911.6 KII84617.1 - 0.059 11.5 0.9 0.084 11.0 0.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Flagellin_N PF00669.15 KII84617.1 - 0.14 11.9 0.8 0.26 11.1 0.2 1.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region YjcZ PF13990.1 KII84617.1 - 0.14 11.2 1.9 1.7 7.6 0.2 2.4 2 0 0 2 2 2 0 YjcZ-like protein Cortex-I_coil PF09304.5 KII84617.1 - 0.16 11.9 0.9 0.29 11.1 0.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil F-box PF00646.28 KII84617.1 - 0.56 9.9 2.3 8.1 6.2 0.4 2.7 2 0 0 2 2 2 0 F-box domain Kinetochor_Ybp2 PF08568.5 KII84620.1 - 6.1e-14 51.2 0.0 1.3e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin MMS19_C PF12460.3 KII84620.1 - 0.0021 16.8 0.1 0.49 9.0 0.1 2.4 1 1 1 2 2 2 2 RNAPII transcription regulator C-terminal ABM PF03992.11 KII84621.1 - 3.4e-07 30.2 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dus PF01207.12 KII84622.1 - 1.9e-52 178.0 0.0 2.3e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KII84622.1 - 0.042 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ABM PF03992.11 KII84623.1 - 2e-06 27.7 0.0 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DIOX_N PF14226.1 KII84624.1 - 4.4e-19 69.1 0.0 8.4e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII84624.1 - 1.1e-10 41.6 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KII84625.1 - 2.5e-33 115.2 35.9 1.3e-32 112.9 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD4L PF06235.6 KII84628.1 - 6.7 6.5 13.9 0.99 9.2 3.8 2.4 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) R3H PF01424.17 KII84629.1 - 2.3e-10 40.0 0.1 6.8e-10 38.4 0.1 1.7 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 KII84629.1 - 1.3e-07 31.4 189.2 0.00041 20.2 9.4 13.2 12 1 0 12 12 12 8 NF-X1 type zinc finger TPPK_C PF12555.3 KII84630.1 - 0.051 13.2 0.5 0.14 11.9 0.4 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Ashwin PF15323.1 KII84630.1 - 0.13 12.2 0.2 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Developmental protein Ldr_toxin PF13940.1 KII84630.1 - 3.6 7.4 5.3 8.3 6.2 1.0 2.9 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system GST_N_3 PF13417.1 KII84631.1 - 9.9e-10 38.5 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII84631.1 - 2.7e-05 24.5 0.0 4.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII84631.1 - 0.0001 22.0 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII84631.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KII84631.1 - 0.0072 16.2 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Amidase PF01425.16 KII84633.1 - 3.3e-86 289.8 0.0 4.1e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Amidase SET PF00856.23 KII84634.1 - 6e-12 46.1 0.0 5e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 KII84634.1 - 4.6e-10 39.1 10.3 4.6e-10 39.1 7.1 2.8 2 1 1 3 3 3 1 MYND finger Peroxin-13_N PF04088.8 KII84635.1 - 1.6e-40 138.6 0.1 3e-40 137.7 0.1 1.5 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KII84635.1 - 2.8e-12 45.9 0.0 4.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII84635.1 - 1.7e-11 43.3 1.3 2.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KII84635.1 - 5.8e-07 28.9 0.9 1.6e-06 27.5 0.6 1.7 1 1 0 1 1 1 1 Variant SH3 domain CotH PF08757.6 KII84637.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 CotH protein Period_C PF12114.3 KII84637.1 - 1.8 8.0 11.8 2 7.9 8.2 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 KII84637.1 - 5 6.5 17.2 6.3 6.2 11.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3774 PF12609.3 KII84637.1 - 6 7.7 11.2 3.6 8.4 6.5 1.6 1 1 1 2 2 2 0 Wound-induced protein CH PF00307.26 KII84639.1 - 2.4e-69 230.2 0.0 7.9e-20 70.9 0.0 4.6 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KII84639.1 - 1.3e-08 34.3 0.0 1.3 8.7 0.0 4.4 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_7 PF13499.1 KII84639.1 - 0.0069 16.5 0.1 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair Pkinase PF00069.20 KII84640.1 - 1.2e-26 93.4 0.0 2.4e-25 89.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84640.1 - 8.6e-22 77.4 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII84640.1 - 0.0053 15.7 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tyrosinase PF00264.15 KII84641.1 - 3.3e-31 109.1 7.6 4.6e-31 108.7 5.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NIR_SIR PF01077.17 KII84642.1 - 0.023 14.0 0.1 1.4 8.2 0.0 2.1 1 1 1 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain Phage_GPA PF05840.8 KII84642.1 - 0.077 11.6 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) RRF_GI PF12614.3 KII84643.1 - 0.36 10.6 5.6 0.67 9.7 1.5 2.0 1 1 1 2 2 2 0 Ribosome recycling factor GST_N_3 PF13417.1 KII84647.1 - 2.3e-09 37.3 0.1 4.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII84647.1 - 4.3e-05 23.4 0.1 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII84647.1 - 0.0098 15.7 1.1 0.019 14.8 0.7 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII84647.1 - 0.058 13.3 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.16 KII84648.1 - 1.1e-50 172.2 4.3 7e-30 103.9 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel BBE PF08031.7 KII84651.1 - 0.26 11.2 3.7 20 5.1 0.2 3.1 3 0 0 3 3 3 0 Berberine and berberine like WW PF00397.21 KII84655.1 - 0.0033 17.2 0.6 0.2 11.5 0.1 2.6 2 0 0 2 2 2 2 WW domain AAA_21 PF13304.1 KII84655.1 - 0.1 12.5 0.8 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain Pmp3 PF01679.12 KII84658.1 - 7.5e-19 67.1 2.6 5.2e-13 48.4 0.2 2.1 2 0 0 2 2 2 2 Proteolipid membrane potential modulator cEGF PF12662.2 KII84659.1 - 0.27 10.9 2.9 32 4.2 1.2 3.8 2 2 0 2 2 2 0 Complement Clr-like EGF-like Antistasin PF02822.9 KII84659.1 - 6.4 7.1 15.8 2.7 8.3 0.1 4.3 5 0 0 5 5 5 0 Antistasin family Phage_GPA PF05840.8 KII84661.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Tyrosinase PF00264.15 KII84662.1 - 3.2e-31 109.2 7.6 4.6e-31 108.7 5.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase HTH_32 PF13565.1 KII84663.1 - 3.6 8.4 8.4 7.4 7.4 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain MFS_1 PF07690.11 KII84664.1 - 1.9e-32 112.3 41.4 1.9e-32 112.3 28.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KII84664.1 - 0.021 12.8 6.6 0.28 9.1 2.3 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DCP1 PF06058.8 KII84666.1 - 4.2e-20 72.0 0.0 3.8e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Dcp1-like decapping family PRP3 PF08572.5 KII84667.1 - 2.8e-66 223.0 0.9 6.1e-66 221.9 0.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KII84667.1 - 3.1e-33 114.1 0.2 1.2e-32 112.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosomal_L16 PF00252.13 KII84668.1 - 5.7e-34 116.7 0.2 6.8e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pyridoxal_deC PF00282.14 KII84669.1 - 2.3e-59 200.7 0.0 3.4e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1257 PF06868.6 KII84669.1 - 0.051 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) UBN2 PF14223.1 KII84670.1 - 9.6e-09 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII84670.1 - 1.2e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KII84670.1 - 2.7e-06 27.0 0.0 3.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII84670.1 - 0.00036 20.3 5.2 0.0006 19.6 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Pyridoxal_deC PF00282.14 KII84671.1 - 5.9e-53 179.6 0.0 8.6e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Bac_surface_Ag PF01103.18 KII84672.1 - 5.2e-40 137.8 0.6 6.5e-40 137.5 0.4 1.1 1 0 0 1 1 1 1 Surface antigen Surf_Ag_VNR PF07244.10 KII84672.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat MatE PF01554.13 KII84673.1 - 7.6e-50 168.6 26.3 2.7e-29 101.8 5.9 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KII84673.1 - 4.9e-06 26.3 8.3 4.9e-06 26.3 5.8 4.5 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.11 KII84674.1 - 1.1e-26 93.4 34.5 1.6e-26 92.9 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ca_hom_mod PF14798.1 KII84674.1 - 0.065 12.1 2.3 0.31 9.9 0.5 2.4 2 0 0 2 2 2 0 Calcium homeostasis modulator MFS_1 PF07690.11 KII84675.1 - 9.7e-26 90.2 33.8 1.5e-25 89.6 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 KII84676.1 - 2.4e-13 50.0 0.0 6.5e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S8 Tri3 PF07428.6 KII84678.1 - 0.053 12.2 0.0 0.11 11.1 0.0 1.4 1 1 0 1 1 1 0 15-O-acetyltransferase Tri3 AATase PF07247.7 KII84678.1 - 0.095 11.2 0.9 0.36 9.3 0.0 2.1 3 0 0 3 3 3 0 Alcohol acetyltransferase Alpha-L-AF_C PF06964.7 KII84680.1 - 2.8e-40 137.9 0.2 2.8e-40 137.9 0.2 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus CBM_6 PF03422.10 KII84680.1 - 3.2 7.9 11.0 0.23 11.6 2.9 2.5 2 1 0 2 2 2 0 Carbohydrate binding module (family 6) Hist_deacetyl PF00850.14 KII84681.1 - 1e-55 189.2 0.0 1.4e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Transaldolase PF00923.14 KII84682.1 - 1.5e-46 158.8 0.2 1.9e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Transaldolase SIN1 PF05422.7 KII84683.1 - 1.9e-45 155.3 0.0 3.6e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 KII84683.1 - 8.1e-07 28.7 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.3 KII84683.1 - 0.00034 20.4 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DDE_3 PF13358.1 KII84685.1 - 1e-05 25.3 0.5 1.1e-05 25.1 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Mito_fiss_reg PF05308.6 KII84689.1 - 0.13 11.6 1.7 0.17 11.2 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4116 PF13475.1 KII84691.1 - 0.0023 17.4 0.7 68 3.0 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) WXG100 PF06013.7 KII84691.1 - 0.0046 16.9 33.8 0.31 11.0 2.6 5.2 4 1 0 4 4 4 3 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.4 KII84691.1 - 0.67 9.8 38.7 2.4 7.9 2.2 4.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KII84691.1 - 1.4 8.0 44.0 5.2 6.2 9.1 3.0 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KII84691.1 - 2.3 7.9 36.5 3.7 7.2 4.5 4.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 KII84691.1 - 4.3 5.6 31.0 0.96 7.7 7.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SR-25 PF10500.4 KII84695.1 - 6.3e-06 25.8 2.3 7.9e-06 25.5 1.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein UBN2_2 PF14227.1 KII84696.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Tautomerase PF01361.16 KII84696.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 2 0 0 2 2 2 0 Tautomerase enzyme UBN2_2 PF14227.1 KII84697.1 - 4.5e-11 42.3 0.0 7.9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII84697.1 - 5.7e-08 32.5 0.0 9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MMS22L_N PF14910.1 KII84701.1 - 0.011 14.0 0.1 0.013 13.7 0.1 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Herpes_ORF11 PF04797.8 KII84705.1 - 0.0014 17.2 0.0 0.002 16.6 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus dUTPase protein DUF1883 PF08980.5 KII84708.1 - 0.17 11.4 0.0 8.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) zf-CCHC PF00098.18 KII84709.1 - 0.0022 17.8 2.7 0.0039 17.0 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KII84709.1 - 0.12 11.9 4.3 0.38 10.2 3.0 2.0 1 1 0 1 1 1 0 GAG-polyprotein viral zinc-finger SpoIIE PF07228.7 KII84710.1 - 7.7e-05 22.4 0.0 0.0007 19.3 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KII84710.1 - 0.0017 17.8 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KII84710.1 - 0.0089 15.4 0.1 0.062 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C TFIIA PF03153.8 KII84710.1 - 3.9 7.2 16.2 4.2 7.1 1.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit POX PF07526.6 KII84710.1 - 5.9 7.1 5.3 0.72 10.0 0.2 1.9 2 0 0 2 2 2 0 Associated with HOX Aldedh PF00171.17 KII84711.1 - 1.9e-122 408.9 0.0 2.2e-122 408.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII84711.1 - 3.3e-07 29.3 0.0 4.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) BAR_2 PF10455.4 KII84712.1 - 2.3e-48 164.5 0.2 6.3e-48 163.1 0.1 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KII84712.1 - 3e-13 49.8 0.2 2e-12 47.1 0.2 1.9 1 1 0 1 1 1 1 BAR domain Uds1 PF15456.1 KII84712.1 - 0.0053 16.7 1.9 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 Up-regulated During Septation Phasin PF05597.6 KII84712.1 - 0.037 13.7 1.9 0.042 13.5 0.0 2.0 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Proteasome PF00227.21 KII84713.1 - 1.7e-47 161.1 0.1 2.1e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KII84713.1 - 9.7e-10 37.5 0.4 2.1e-09 36.4 0.3 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal EMP24_GP25L PF01105.19 KII84714.1 - 3.3e-41 141.0 0.0 3.8e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL49_5 PF05702.6 KII84714.1 - 0.096 12.5 1.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Ribosomal_S10 PF00338.17 KII84715.1 - 1.3e-23 82.6 0.1 2e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Phage_RpbA PF10789.4 KII84715.1 - 0.08 12.7 0.8 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA EnY2 PF10163.4 KII84716.1 - 7.3e-20 70.6 0.1 8.2e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Mago_nashi PF02792.9 KII84717.1 - 2.4e-71 238.0 0.2 2.7e-71 237.8 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Pkinase PF00069.20 KII84719.1 - 2.4e-28 98.9 0.0 3e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84719.1 - 8.6e-11 41.3 0.0 9.7e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII84719.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRG PF05712.8 KII84721.1 - 5.1e-47 159.3 0.0 6.9e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KII84721.1 - 4.3e-10 39.1 0.4 8.3e-10 38.2 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KII84721.1 - 0.041 13.5 1.2 0.076 12.7 0.8 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Redoxin PF08534.5 KII84722.1 - 1.6e-29 102.3 0.0 2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KII84722.1 - 7.4e-12 45.0 0.0 9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII84723.1 - 3.9e-30 104.3 0.0 5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KII84723.1 - 3.8e-12 45.9 0.0 4.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KII84723.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like TMEM154 PF15102.1 KII84724.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 KII84724.1 - 0.0021 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KII84724.1 - 0.04 12.1 0.1 0.062 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2370 PF10176.4 KII84724.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Neurensin PF14927.1 KII84724.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Neurensin HA2 PF04408.18 KII84726.1 - 1.1e-27 96.0 0.1 2.3e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KII84726.1 - 7.5e-24 83.7 0.0 1.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KII84726.1 - 4.6e-11 42.4 0.0 9.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII84726.1 - 3.1e-07 30.0 0.1 8.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII84726.1 - 5.6e-05 23.2 0.0 0.00019 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KII84726.1 - 0.00015 21.2 0.2 0.00046 19.6 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KII84726.1 - 0.011 15.4 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.10 KII84726.1 - 0.019 14.8 0.0 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KII84726.1 - 0.026 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KII84726.1 - 0.032 13.1 0.0 0.063 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KII84726.1 - 0.035 13.2 0.2 0.31 10.1 0.0 2.4 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 KII84726.1 - 0.063 12.4 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 KII84726.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KII84726.1 - 0.091 11.8 0.1 0.38 9.8 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin Proteasome PF00227.21 KII84727.1 - 8e-29 100.2 0.1 9.6e-29 100.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 KII84727.1 - 0.059 12.9 0.2 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain O-FucT PF10250.4 KII84728.1 - 2.2e-09 36.8 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HAD_2 PF13419.1 KII84728.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DnaJ-X PF14308.1 KII84729.1 - 1.4e-50 171.4 0.3 1.4e-50 171.4 0.2 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KII84729.1 - 2.1e-26 91.4 1.1 2.1e-26 91.4 0.8 2.3 2 1 0 2 2 2 1 DnaJ domain DUF3323 PF11796.3 KII84729.1 - 0.17 11.1 7.0 2.2 7.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) PEX11 PF05648.9 KII84729.1 - 0.25 10.5 1.7 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) tRNA-synt_1b PF00579.20 KII84730.1 - 1.4e-56 191.7 0.0 1e-55 188.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2360 PF10152.4 KII84730.1 - 0.43 10.8 4.3 0.73 10.1 3.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FtsJ PF01728.14 KII84731.1 - 1.5e-40 139.0 0.0 4.6e-40 137.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase RWP-RK PF02042.10 KII84731.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RWP-RK domain APH PF01636.18 KII84732.1 - 2.8e-17 63.2 0.7 3.4e-17 62.9 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII84732.1 - 0.00053 19.6 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KII84732.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DinB_2 PF12867.2 KII84733.1 - 0.048 13.9 0.1 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily APH PF01636.18 KII84734.1 - 8.4e-17 61.6 1.2 1.8e-16 60.5 0.8 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII84734.1 - 0.00019 21.1 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KII84734.1 - 0.029 13.5 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 KII84734.1 - 0.11 11.8 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DinB_2 PF12867.2 KII84735.1 - 0.0038 17.5 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 DinB superfamily APH PF01636.18 KII84736.1 - 9.6e-18 64.7 0.1 1.5e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII84736.1 - 0.00014 21.5 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KII84736.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain PyocinActivator PF11112.3 KII84737.1 - 0.071 12.9 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyocin activator protein PrtN DinB_2 PF12867.2 KII84737.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 DinB superfamily PhzC-PhzF PF02567.11 KII84738.1 - 9e-41 139.9 0.0 1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 KII84738.1 - 0.006 15.4 0.0 0.051 12.3 0.0 1.9 2 0 0 2 2 2 1 Proline racemase Septin PF00735.13 KII84739.1 - 5e-113 376.7 0.2 7.6e-113 376.2 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KII84739.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KII84739.1 - 6.9e-07 28.5 0.0 1.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KII84739.1 - 4.8e-06 26.1 0.1 0.00018 20.9 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KII84739.1 - 0.0006 19.3 0.8 0.036 13.5 0.1 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 KII84739.1 - 0.00089 18.4 0.0 0.002 17.2 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 KII84739.1 - 0.00096 19.3 1.4 0.0068 16.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KII84739.1 - 0.0013 19.2 0.1 0.0044 17.5 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KII84739.1 - 0.0026 17.1 0.3 0.01 15.2 0.2 2.0 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 KII84739.1 - 0.0067 16.4 1.0 0.036 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 KII84739.1 - 0.0068 16.7 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 KII84739.1 - 0.0095 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KII84739.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 KII84739.1 - 0.016 15.0 0.4 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KII84739.1 - 0.019 14.6 2.6 1.5 8.4 0.2 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein MobB PF03205.9 KII84739.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KII84739.1 - 0.021 14.6 7.3 1 9.1 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 KII84739.1 - 0.034 13.8 1.8 0.07 12.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KII84739.1 - 0.035 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 KII84739.1 - 0.036 12.9 0.1 0.078 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 KII84739.1 - 0.053 13.4 0.3 0.27 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 KII84739.1 - 0.082 12.0 0.5 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SE PF00437.15 KII84739.1 - 0.082 11.7 0.1 0.23 10.3 0.1 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 KII84739.1 - 0.094 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FeoB_N PF02421.13 KII84739.1 - 0.12 11.6 0.1 0.35 10.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 KII84739.1 - 0.13 11.7 1.5 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KII84739.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KII84739.1 - 0.2 11.8 0.4 0.75 9.9 0.0 2.2 2 1 0 2 2 1 0 RNA helicase AAA PF00004.24 KII84739.1 - 0.2 11.8 2.0 0.97 9.6 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Myc-LZ PF02344.10 KII84739.1 - 0.3 10.7 4.5 5.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain TFIIIC_sub6 PF10419.4 KII84740.1 - 2e-09 36.7 0.0 3.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit CD99L2 PF12301.3 KII84740.1 - 0.089 12.4 5.4 0.12 12.0 3.7 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 SET PF00856.23 KII84741.1 - 7.3e-10 39.3 0.3 2e-08 34.7 0.2 2.4 1 1 0 1 1 1 1 SET domain DUF3433 PF11915.3 KII84743.1 - 2e-20 72.7 2.1 2e-20 72.7 1.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3433) Hydrophobin PF01185.13 KII84744.1 - 2.1e-20 72.9 10.9 2.5e-20 72.7 7.6 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Tubulin PF00091.20 KII84745.1 - 3.6e-69 232.8 0.0 7.2e-69 231.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KII84745.1 - 1.1e-48 164.4 0.2 1.7e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KII84745.1 - 1e-06 28.7 0.0 2.9e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KII84745.1 - 0.022 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Sld5 PF05916.6 KII84746.1 - 3.3e-05 24.1 0.3 8.3e-05 22.8 0.2 1.8 1 1 0 1 1 1 1 GINS complex protein Herpes_UL14 PF03580.9 KII84746.1 - 0.071 12.9 0.9 0.13 12.0 0.6 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF3433 PF11915.3 KII84748.1 - 9e-21 73.8 3.5 9e-21 73.8 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) 7TM_GPCR_Srb PF02175.11 KII84748.1 - 0.071 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb DUF3382 PF11862.3 KII84748.1 - 0.08 12.8 2.2 0.1 12.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) COX2_TM PF02790.10 KII84748.1 - 0.15 11.9 1.6 0.29 11.1 1.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain CPSase_L_D2 PF02786.12 KII84749.1 - 3.3e-116 385.9 0.6 3e-84 281.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KII84749.1 - 1.7e-46 156.9 0.0 6.9e-46 154.9 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KII84749.1 - 9.5e-44 149.1 0.0 1e-42 145.8 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KII84749.1 - 1.2e-43 148.1 0.0 2.9e-43 146.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 KII84749.1 - 5.9e-42 142.3 0.2 3.9e-41 139.6 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KII84749.1 - 2.7e-40 136.8 0.0 3.8e-20 72.0 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KII84749.1 - 2.9e-37 128.1 0.1 3.8e-22 78.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KII84749.1 - 1.6e-36 125.5 0.0 4e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KII84749.1 - 2.7e-21 75.6 0.4 4.1e-09 35.6 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KII84749.1 - 5.4e-19 67.9 0.0 3.6e-18 65.2 0.0 2.6 3 0 0 3 3 2 1 MGS-like domain ATP-grasp PF02222.17 KII84749.1 - 2.6e-17 62.7 0.2 1.8e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KII84749.1 - 5.3e-17 61.8 0.3 1.2e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KII84749.1 - 1.7e-05 24.4 0.1 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KII84749.1 - 2.3e-05 24.3 0.1 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KII84749.1 - 7.4e-05 22.2 0.1 0.0021 17.5 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KII84749.1 - 0.0027 17.1 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family ATP-grasp_5 PF13549.1 KII84749.1 - 0.12 11.5 0.0 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ATP-grasp domain DUF4231 PF14015.1 KII84750.1 - 0.037 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) CBFD_NFYB_HMF PF00808.18 KII84751.1 - 1.3e-16 60.3 1.3 2.4e-16 59.5 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KII84751.1 - 4e-08 33.2 0.2 5.7e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 KII84751.1 - 0.13 12.0 1.4 0.2 11.4 1.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2201_N PF13203.1 KII84751.1 - 0.3 10.2 2.4 0.35 9.9 1.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain FAD_binding_4 PF01565.18 KII84753.1 - 3.2e-18 65.5 1.7 5.4e-18 64.8 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain TAFII28 PF04719.9 KII84754.1 - 3.6e-25 87.5 0.0 4.9e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 KII84754.1 - 0.02 14.9 0.1 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-H2C2_2 PF13465.1 KII84755.1 - 1.3e-08 34.6 6.8 1.3e-07 31.5 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KII84755.1 - 1.2e-06 28.5 13.1 1.2e-05 25.3 0.5 4.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII84755.1 - 0.00048 20.2 11.4 0.0056 16.9 0.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KII84755.1 - 0.00085 19.1 4.5 0.47 10.4 0.1 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KII84755.1 - 0.025 14.7 0.4 4.2 7.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3505 PF12013.3 KII84755.1 - 0.094 12.9 0.9 9.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) zf-Di19 PF05605.7 KII84755.1 - 0.92 9.6 6.6 2.3 8.3 0.6 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3433 PF11915.3 KII84757.1 - 4.4e-20 71.6 4.9 1.2e-19 70.2 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Deltaretro_Tax PF05599.6 KII84759.1 - 0.024 14.9 3.6 0.04 14.2 2.5 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein zf-C2H2_4 PF13894.1 KII84762.1 - 0.00034 20.7 11.5 0.02 15.2 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII84762.1 - 0.06 13.5 0.5 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KII84762.1 - 1.8 9.0 15.3 0.19 12.1 1.7 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII84762.1 - 4 7.8 6.6 11 6.4 2.0 3.0 2 0 0 2 2 2 0 Zinc-finger double domain DUF3948 PF13134.1 KII84764.1 - 0.2 11.1 1.0 0.5 9.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) cEGF PF12662.2 KII84764.1 - 0.36 10.5 15.6 0.075 12.6 0.8 4.9 4 1 1 5 5 5 0 Complement Clr-like EGF-like EamA PF00892.15 KII84765.1 - 2e-23 82.7 23.8 1.3e-12 47.9 4.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KII84765.1 - 0.00041 20.5 27.4 0.039 14.1 4.4 3.2 2 1 0 3 3 3 2 Multidrug resistance efflux transporter Gemini_AC4_5_2 PF08464.5 KII84765.1 - 0.009 15.7 0.9 1.2 8.9 0.1 3.0 3 0 0 3 3 3 1 Geminivirus AC4/5 conserved region DUF3021 PF11457.3 KII84765.1 - 0.032 14.1 0.7 0.032 14.1 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) ATG22 PF11700.3 KII84768.1 - 3.7e-147 490.6 14.4 4.2e-147 490.4 10.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KII84768.1 - 2.6e-07 29.6 56.9 0.00023 19.9 9.8 3.3 2 2 1 3 3 3 3 Major Facilitator Superfamily THEG PF14912.1 KII84769.1 - 0.046 14.2 2.9 0.046 14.2 2.0 2.8 1 1 1 2 2 2 0 Testicular haploid expressed repeat Mitofilin PF09731.4 KII84769.1 - 0.67 8.5 8.8 0.69 8.4 6.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40_alt PF14077.1 KII84770.1 - 0.32 10.6 0.9 0.63 9.7 0.6 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif 2OG-FeII_Oxy_3 PF13640.1 KII84771.1 - 8.1e-13 48.7 0.0 6.4e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KII84771.1 - 7.5e-06 25.5 0.0 9.9e-05 21.9 0.0 2.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EPL1 PF10513.4 KII84772.1 - 4.2e-16 59.5 3.6 3e-15 56.8 0.0 2.9 3 0 0 3 3 3 1 Enhancer of polycomb-like adh_short PF00106.20 KII84774.1 - 2.9e-24 85.8 1.4 3.5e-24 85.6 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII84774.1 - 5.3e-09 35.9 0.2 7e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII84774.1 - 7e-09 35.7 0.0 9.2e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HEM4 PF02602.10 KII84774.1 - 0.0018 17.5 0.3 0.0039 16.4 0.1 1.5 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD Xan_ur_permease PF00860.15 KII84775.1 - 2.4e-25 88.8 31.2 8.2e-15 54.1 9.2 2.5 2 1 0 2 2 2 2 Permease family FA_hydroxylase PF04116.8 KII84776.1 - 1.4e-12 47.9 21.0 1.4e-12 47.9 14.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DDE_Tnp_4 PF13359.1 KII84777.1 - 1.6e-16 60.2 0.0 2.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SNARE_assoc PF09335.6 KII84780.1 - 1.6e-14 54.1 7.2 1.6e-14 54.1 5.0 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein Pkinase_Tyr PF07714.12 KII84781.1 - 6.1e-39 133.6 0.0 1e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII84781.1 - 5.7e-37 127.2 0.0 1.1e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4238 PF14022.1 KII84781.1 - 7.1e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.18 KII84781.1 - 5.2e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KII84781.1 - 0.00054 19.0 0.0 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Peptidase_S9 PF00326.16 KII84782.1 - 8.1e-39 133.0 0.0 1.1e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII84782.1 - 6.3e-11 42.2 0.3 2.1e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KII84782.1 - 2.2e-06 27.1 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KII84782.1 - 4.4e-06 26.7 0.4 2.3e-05 24.3 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KII84782.1 - 0.0043 16.6 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KII84782.1 - 0.0067 15.9 0.1 1.2 8.6 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold PD40 PF07676.7 KII84782.1 - 0.042 13.5 3.9 0.063 12.9 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AXE1 PF05448.7 KII84782.1 - 0.11 10.9 0.4 1.3 7.4 0.0 2.5 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Cys_Met_Meta_PP PF01053.15 KII84783.1 - 1.2e-145 484.6 0.0 1.4e-145 484.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KII84783.1 - 8.6e-14 51.3 0.5 2.4e-13 49.8 0.2 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KII84783.1 - 7.6e-10 38.0 0.5 7.6e-10 38.0 0.4 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KII84783.1 - 1.3e-09 37.4 0.0 2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KII84783.1 - 5.7e-06 25.6 0.1 1.3e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KII84783.1 - 4e-05 22.4 0.1 6.1e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 KII84783.1 - 0.00019 19.8 0.1 0.00026 19.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase FAD_binding_3 PF01494.14 KII84784.1 - 4.9e-22 78.4 0.0 6.3e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KII84784.1 - 0.0013 18.6 0.1 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII84784.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KII84784.1 - 0.0073 15.1 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KII84784.1 - 0.0082 15.0 0.4 0.38 9.6 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KII84784.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 KII84784.1 - 0.031 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII84784.1 - 0.046 12.8 0.1 0.095 11.7 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 KII84784.1 - 0.084 12.9 0.0 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cache_1 PF02743.13 KII84784.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Cache domain HI0933_like PF03486.9 KII84784.1 - 0.17 10.3 0.0 0.32 9.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein dsrm PF00035.20 KII84788.1 - 0.021 15.3 0.7 1.3 9.6 0.0 3.4 3 0 0 3 3 3 0 Double-stranded RNA binding motif DUF908 PF06012.7 KII84788.1 - 0.49 9.6 1.3 0.79 8.9 0.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PhyH PF05721.8 KII84789.1 - 1.2e-12 48.3 0.1 1.7e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SIR2 PF02146.12 KII84790.1 - 3.7e-32 111.4 0.0 8.3e-31 107.0 0.0 2.5 1 1 0 1 1 1 1 Sir2 family CBM_1 PF00734.13 KII84790.1 - 5.8 6.6 6.8 6.9 6.4 0.2 2.8 3 0 0 3 3 3 0 Fungal cellulose binding domain DUF4407 PF14362.1 KII84792.1 - 0.033 13.1 0.8 0.048 12.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 KII84792.1 - 0.035 13.7 2.9 0.12 12.0 2.0 1.8 1 1 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 KII84792.1 - 0.056 11.8 2.5 0.083 11.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_16 PF13191.1 KII84792.1 - 0.17 11.8 7.5 0.061 13.3 0.6 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF4200 PF13863.1 KII84792.1 - 0.35 10.8 6.9 0.78 9.6 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 KII84792.1 - 0.45 10.0 5.2 0.75 9.3 3.6 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KII84792.1 - 1.4 7.8 4.8 2.1 7.3 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DASH_Spc19 PF08287.6 KII84792.1 - 3.5 7.2 10.2 8.2 6.0 7.1 1.6 1 0 0 1 1 1 0 Spc19 DUF4407 PF14362.1 KII84794.1 - 2.6e-05 23.3 1.8 3.7e-05 22.8 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4201 PF13870.1 KII84794.1 - 0.00062 19.2 2.1 0.00062 19.2 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) HemX PF04375.9 KII84794.1 - 0.00072 18.2 1.5 0.0012 17.5 1.0 1.3 1 0 0 1 1 1 1 HemX AAA_27 PF13514.1 KII84794.1 - 0.0017 16.1 6.6 0.0024 15.6 4.5 1.1 1 0 0 1 1 1 1 AAA domain Lzipper-MIP1 PF14389.1 KII84794.1 - 0.018 15.1 1.1 0.073 13.1 0.0 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 AKNA PF12443.3 KII84794.1 - 0.025 14.5 6.4 0.13 12.2 0.7 2.9 1 1 2 3 3 3 0 AT-hook-containing transcription factor bZIP_1 PF00170.16 KII84794.1 - 0.067 13.1 9.7 0.26 11.2 0.0 3.0 3 0 0 3 3 3 0 bZIP transcription factor TMF_TATA_bd PF12325.3 KII84794.1 - 0.12 12.0 8.6 0.074 12.7 0.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KII84794.1 - 0.17 11.8 10.1 0.12 12.3 2.6 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.6 KII84794.1 - 0.22 11.5 5.9 0.056 13.4 0.6 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.6 KII84794.1 - 0.23 11.2 12.8 0.8 9.4 8.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KII84794.1 - 0.29 10.2 8.0 0.27 10.4 4.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF607 PF04678.8 KII84794.1 - 0.49 10.2 2.4 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 APG6 PF04111.7 KII84794.1 - 0.62 9.0 9.8 1 8.3 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 KII84794.1 - 1.6 8.5 6.0 0.68 9.6 0.1 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF972 PF06156.8 KII84794.1 - 1.8 8.9 9.7 6 7.2 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) HAUS6_N PF14661.1 KII84794.1 - 3.6 6.8 12.6 0.09 12.1 2.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.10 KII84794.1 - 6.5 6.3 7.5 5.8 6.4 0.4 2.6 2 1 0 2 2 2 0 Septum formation initiator Tmemb_cc2 PF10267.4 KII84794.1 - 7.2 5.0 10.3 66 1.9 7.2 2.0 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PAP2 PF01569.16 KII84796.1 - 4.3e-10 39.3 8.8 4.3e-10 39.3 6.1 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KII84796.1 - 1.6e-07 31.0 10.9 3.6e-07 29.9 7.6 1.5 1 0 0 1 1 1 1 PAP2 superfamily GPCR_chapero_1 PF11904.3 KII84796.1 - 0.0092 15.1 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 GPCR-chaperone DUF3579 PF12112.3 KII84796.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) PAP2_C PF14360.1 KII84796.1 - 2.9 8.2 11.4 0.4 10.9 4.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Peptidase_M36 PF02128.10 KII84797.1 - 7.9e-132 439.6 7.7 2.4e-131 438.0 5.4 1.9 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KII84797.1 - 2.6e-08 33.1 1.2 5.8e-08 32.0 0.9 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 KII84797.1 - 0.014 15.1 0.1 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_23 PF13489.1 KII84799.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII84799.1 - 6.4e-05 23.5 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII84799.1 - 6.6e-05 23.3 0.0 0.00017 22.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII84799.1 - 0.0012 19.2 0.0 0.0042 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII84799.1 - 0.0068 16.0 0.0 0.046 13.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KII84799.1 - 0.059 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short_C2 PF13561.1 KII84801.1 - 3.7e-36 125.1 0.3 4.2e-36 124.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII84801.1 - 5.9e-26 91.3 4.2 7.4e-26 91.0 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII84801.1 - 2.8e-12 46.6 2.2 2.3e-11 43.7 1.9 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KII84801.1 - 0.00014 21.3 1.0 0.00071 19.0 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flavodoxin_1 PF00258.20 KII84801.1 - 0.013 15.4 0.1 0.057 13.4 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin Flavodoxin_5 PF12724.2 KII84801.1 - 0.019 14.9 0.7 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Flavodoxin domain THF_DHG_CYH_C PF02882.14 KII84801.1 - 0.041 12.9 1.7 0.074 12.1 1.0 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.1 KII84802.1 - 1e-30 107.2 0.5 1.2e-30 107.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII84802.1 - 1.3e-22 80.4 4.8 3.2e-21 75.9 3.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII84802.1 - 2e-09 37.3 3.0 7.5e-09 35.4 1.2 2.2 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.5 KII84802.1 - 0.013 14.6 0.0 0.055 12.5 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 KII84802.1 - 0.027 14.1 1.4 0.046 13.3 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 KII84802.1 - 0.059 12.9 7.1 1.8 8.1 0.5 3.0 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 KII84802.1 - 0.093 12.1 0.3 0.16 11.3 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 KII84803.1 - 4.4e-12 46.0 0.2 4.9e-11 42.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII84803.1 - 1.2e-08 34.8 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII84803.1 - 0.00028 19.7 1.5 0.0012 17.6 1.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KII84803.1 - 0.00081 19.3 2.0 0.0021 17.9 1.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII84803.1 - 0.0092 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KII84803.1 - 0.027 13.7 0.0 0.23 10.6 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family RhoGEF PF00621.15 KII84804.1 - 1.8e-06 27.9 0.0 1.9e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.15 KII84805.1 - 3.3e-41 141.1 5.7 3.3e-41 141.1 4.0 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KII84805.1 - 1e-13 50.9 0.0 1.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KII84805.1 - 9.3e-12 44.4 0.1 1.8e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain NUDIX_2 PF13869.1 KII84807.1 - 2.3e-84 281.4 0.0 2.6e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Abhydrolase_3 PF07859.8 KII84808.1 - 1.2e-10 41.3 0.1 9.9e-10 38.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KII84808.1 - 2.2e-06 26.7 0.0 3.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 KII84808.1 - 2.3e-06 27.4 0.1 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII84808.1 - 0.00019 20.2 0.1 0.00029 19.6 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.6 KII84808.1 - 0.022 13.5 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AstA PF04958.7 KII84808.1 - 0.026 12.9 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Abhydrolase_3 PF07859.8 KII84809.1 - 7.7e-14 51.7 0.2 1.1e-12 48.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII84809.1 - 3.2e-08 33.4 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII84809.1 - 3.3e-05 22.8 0.1 0.00088 18.0 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 KII84809.1 - 0.00016 20.6 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KII84809.1 - 0.0011 18.9 3.8 0.0023 17.8 2.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII84809.1 - 0.038 13.2 0.0 0.26 10.4 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KII84809.1 - 0.045 12.5 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.8 KII84810.1 - 1.3e-14 54.2 0.4 5.4e-14 52.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII84810.1 - 1e-07 31.8 0.1 1.5e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII84810.1 - 1.9e-05 23.6 0.0 3.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 KII84810.1 - 2.3e-05 23.3 0.1 0.00075 18.3 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KII84810.1 - 2.6e-05 24.2 0.8 3.2e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII84810.1 - 0.00014 21.1 0.0 0.0016 17.6 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Ras PF00071.17 KII84811.1 - 3.8e-55 185.6 0.0 4.4e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII84811.1 - 2.4e-18 66.7 0.0 3.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII84811.1 - 1.2e-13 50.6 0.0 1.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII84811.1 - 9.2e-07 28.2 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KII84811.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KII84811.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KII84811.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KII84811.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 KII84811.1 - 0.1 12.5 0.2 0.62 10.0 0.1 2.0 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KII84811.1 - 0.13 11.4 0.1 0.25 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KII84811.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KII84811.1 - 0.14 10.8 1.1 2.8 6.5 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Methyltransf_9 PF08003.6 KII84812.1 - 0.019 13.6 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF4157 PF13699.1 KII84813.1 - 0.062 13.4 0.5 0.16 12.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Polysacc_lyase PF14099.1 KII84814.1 - 0.00031 20.4 0.4 0.0012 18.5 0.3 1.8 1 1 0 1 1 1 1 Polysaccharide lyase Hydrophobin PF01185.13 KII84815.1 - 2.9e-14 53.2 11.9 4e-14 52.8 8.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Pyr_redox_3 PF13738.1 KII84818.1 - 7.3e-23 81.6 0.0 8.5e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII84818.1 - 7.2e-12 45.6 0.0 3.3e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII84818.1 - 4.6e-11 41.6 0.0 1.7e-09 36.4 0.0 2.7 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 KII84818.1 - 4.9e-10 38.8 0.8 1.2e-07 31.0 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII84818.1 - 4.5e-09 36.2 1.4 8.3e-08 32.1 0.1 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KII84818.1 - 2e-08 33.5 0.4 7.3e-05 21.8 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KII84818.1 - 5e-08 33.2 2.2 0.0043 17.4 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII84818.1 - 1.8e-06 27.2 2.0 8.9e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII84818.1 - 3.6e-05 23.6 4.0 0.0094 15.7 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KII84818.1 - 0.00011 22.3 0.1 0.063 13.3 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KII84818.1 - 0.00014 20.8 6.1 0.018 13.9 0.9 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KII84818.1 - 0.00027 20.5 4.4 0.14 11.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KII84818.1 - 0.0003 19.7 10.1 0.0021 16.9 1.5 2.6 3 0 0 3 3 3 2 FAD binding domain Amino_oxidase PF01593.19 KII84818.1 - 0.00062 18.9 0.0 0.035 13.1 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KII84818.1 - 0.0017 18.0 1.1 0.0017 18.0 0.8 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KII84818.1 - 0.0021 16.6 6.2 0.079 11.4 1.6 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 KII84818.1 - 0.0023 17.0 2.1 0.047 12.7 0.4 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 KII84818.1 - 0.0078 16.4 0.1 0.12 12.5 0.0 2.4 3 0 0 3 3 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KII84818.1 - 0.0078 15.6 0.5 0.016 14.5 0.3 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KII84818.1 - 0.029 13.5 0.0 6.1 5.9 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KII84818.1 - 0.079 12.9 4.7 0.62 10.0 0.7 3.0 3 0 0 3 3 3 0 NADH(P)-binding ThiF PF00899.16 KII84818.1 - 0.19 11.5 1.8 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.14 KII84818.1 - 0.27 10.2 0.8 2.5 7.0 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KII84818.1 - 2.8 7.6 4.0 1.9 8.1 0.6 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DEAD PF00270.24 KII84820.1 - 1.7e-05 24.3 0.0 2.7e-05 23.7 0.0 1.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KII84820.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EOS1 PF12326.3 KII84821.1 - 3.5e-17 62.4 0.0 4.5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 N-glycosylation protein Diphthamide_syn PF01866.12 KII84822.1 - 5.8e-68 229.3 0.0 7.6e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_11 PF13414.1 KII84823.1 - 1.8e-11 43.4 2.5 0.00013 21.5 0.0 5.3 6 0 0 6 6 6 2 TPR repeat TPR_16 PF13432.1 KII84823.1 - 5.2e-11 42.9 3.8 0.00015 22.3 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII84823.1 - 1.2e-10 40.4 6.8 0.01 15.6 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII84823.1 - 3.1e-09 36.6 9.1 0.00025 21.4 0.0 6.0 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII84823.1 - 6.2e-08 32.8 2.7 1.6 9.1 0.1 5.4 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KII84823.1 - 3.1e-06 26.9 6.8 3.5 8.0 0.0 6.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KII84823.1 - 2.2e-05 23.8 0.7 1.5 8.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII84823.1 - 3.5e-05 23.6 4.7 0.18 11.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 KII84823.1 - 0.0033 16.5 0.1 0.32 10.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII84823.1 - 0.026 14.2 0.2 16 5.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII84823.1 - 0.6 10.6 4.3 38 5.0 0.3 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KII84825.1 - 6.1e-53 176.3 10.1 4.1e-14 51.9 0.3 7.0 2 2 3 7 7 7 6 TPR repeat TPR_1 PF00515.23 KII84825.1 - 1.1e-36 122.9 10.0 1.9e-07 30.4 0.0 10.6 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KII84825.1 - 1.4e-36 121.4 11.3 9.3e-07 28.3 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 KII84825.1 - 4.3e-21 75.0 11.1 1.5e-06 28.6 0.0 5.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KII84825.1 - 1.1e-20 72.0 6.1 6.4e-05 22.8 0.0 8.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KII84825.1 - 1.2e-16 60.3 13.4 2e-05 24.4 0.0 6.7 3 1 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KII84825.1 - 2.8e-16 58.5 12.7 3.6e-06 27.1 0.0 8.4 6 3 3 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII84825.1 - 2.8e-14 53.2 8.0 1.5e-05 25.2 0.0 5.7 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KII84825.1 - 5.6e-14 50.7 1.5 0.00013 21.4 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KII84825.1 - 3.8e-12 45.0 3.8 0.02 14.6 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KII84825.1 - 1.7e-10 40.9 5.0 0.00024 21.1 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KII84825.1 - 3.4e-10 39.6 8.2 0.0019 18.0 0.0 6.1 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII84825.1 - 1.7e-05 24.9 7.9 0.047 14.1 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KII84825.1 - 0.011 14.7 8.3 0.056 12.4 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 KII84825.1 - 0.013 15.3 2.1 7.3 6.4 0.2 4.3 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.1 KII84825.1 - 0.022 14.8 5.5 9.3 6.4 0.0 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KII84825.1 - 0.19 11.7 6.7 12 5.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KII84825.1 - 0.47 9.7 2.9 7.7 5.8 0.1 3.9 3 0 0 3 3 3 0 SHNi-TPR UCR_Fe-S_N PF10399.4 KII84825.1 - 0.71 9.0 3.3 1.6 7.9 2.3 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Piwi PF02171.12 KII84826.1 - 7.6e-61 205.7 0.0 1.9e-60 204.3 0.0 1.6 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 KII84826.1 - 1.9e-18 66.0 0.1 4.6e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 KII84826.1 - 1.9e-13 49.5 0.1 6.1e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Zip PF02535.17 KII84827.1 - 1.1e-51 175.8 0.7 1.6e-51 175.2 0.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Fungal_trans PF04082.13 KII84828.1 - 1.7e-22 79.5 1.6 2.6e-22 78.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84828.1 - 2e-07 30.7 6.7 3.7e-07 29.9 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 KII84829.1 - 2.1e-14 53.2 0.0 1.3e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.9 KII84830.1 - 3.5e-45 153.5 0.2 5e-45 153.0 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 KII84830.1 - 0.33 10.1 4.2 0.99 8.5 0.0 3.0 3 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase COesterase PF00135.23 KII84831.1 - 9e-76 255.6 0.0 1.2e-75 255.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII84831.1 - 0.0012 18.4 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII84831.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family HNH_2 PF13391.1 KII84833.1 - 0.0041 16.8 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF4332 PF14229.1 KII84834.1 - 0.052 13.5 0.6 0.089 12.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HNH_2 PF13391.1 KII84835.1 - 0.015 15.0 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease HNH_2 PF13391.1 KII84836.1 - 0.017 14.8 0.1 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease MFS_1 PF07690.11 KII84837.1 - 2.6e-26 92.1 32.7 3.6e-26 91.7 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 KII84838.1 - 7.2e-38 131.0 4.0 1.1e-36 127.2 3.1 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KII84838.1 - 1.2e-14 55.0 10.3 1.4e-13 51.4 7.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KII84838.1 - 8.5e-12 44.9 3.2 8.5e-12 44.9 2.2 2.7 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KII84838.1 - 3.3e-09 36.4 0.2 9.4e-09 34.9 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase MR_MLE_C PF13378.1 KII84838.1 - 0.027 14.4 1.5 0.12 12.4 0.3 2.6 2 1 0 2 2 2 0 Enolase C-terminal domain-like eIF-5a PF01287.15 KII84838.1 - 0.029 14.3 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Radical_SAM PF04055.16 KII84838.1 - 0.072 13.2 0.1 2.2 8.4 0.0 2.8 2 1 1 3 3 3 0 Radical SAM superfamily Peptidase_M48 PF01435.13 KII84839.1 - 4e-44 150.8 0.0 5.4e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2798 PF11391.3 KII84839.1 - 0.014 15.1 2.4 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Peptidase_M56 PF05569.6 KII84839.1 - 0.018 14.0 0.2 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 EthD PF07110.6 KII84840.1 - 3e-10 40.8 0.0 4.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 EthD domain SHOCT PF09851.4 KII84840.1 - 0.25 10.8 1.9 9.6 5.8 0.4 2.4 2 0 0 2 2 2 0 Short C-terminal domain EthD PF07110.6 KII84841.1 - 1.2e-11 45.4 0.0 1.4e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 EthD domain WD40 PF00400.27 KII84842.1 - 5.2e-53 175.1 16.8 2e-08 33.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KII84842.1 - 0.00013 20.2 0.5 2.1 6.3 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 TFIIS_M PF07500.9 KII84843.1 - 8.1e-34 116.1 3.2 3.9e-33 113.9 0.2 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KII84843.1 - 2.4e-15 55.8 11.2 4.1e-15 55.1 7.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KII84843.1 - 1.3e-13 50.1 0.7 1.3e-13 50.1 0.5 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF3216 PF11505.3 KII84843.1 - 0.1 12.3 0.7 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Mito_carr PF00153.22 KII84846.1 - 2.7e-20 71.8 4.0 4e-08 32.8 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad60-SLD PF11976.3 KII84847.1 - 3.9e-14 52.0 0.0 4.9e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KII84847.1 - 0.00026 20.3 0.0 0.00032 20.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 KII84847.1 - 0.00028 20.7 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 GLUT4 regulating protein TUG zf-CSL PF05207.8 KII84848.1 - 1.9e-23 81.6 0.6 2.3e-23 81.4 0.4 1.1 1 0 0 1 1 1 1 CSL zinc finger Shisa PF13908.1 KII84849.1 - 0.14 12.2 3.8 0.18 11.9 2.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Prominin PF05478.6 KII84849.1 - 0.15 9.6 2.8 0.16 9.4 2.0 1.0 1 0 0 1 1 1 0 Prominin NB PF04159.8 KII84849.1 - 0.23 11.1 3.7 0.29 10.8 2.6 1.2 1 0 0 1 1 1 0 NB glycoprotein DUF2273 PF10031.4 KII84849.1 - 5.9 6.5 8.3 8.5 6.0 5.7 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) GFO_IDH_MocA PF01408.17 KII84850.1 - 2.5e-16 60.2 0.1 4.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GIDA PF01134.17 KII84851.1 - 4.4e-136 453.8 0.0 1.8e-134 448.5 0.0 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KII84851.1 - 5e-15 55.3 0.0 1.3e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 FAD_binding_2 PF00890.19 KII84851.1 - 0.00027 19.9 2.2 0.43 9.3 0.0 2.7 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KII84851.1 - 0.015 15.1 0.7 0.077 12.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KII84851.1 - 0.02 14.8 2.4 0.13 12.1 1.6 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII84851.1 - 0.036 14.1 0.3 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII84851.1 - 0.042 12.3 1.4 3.5 6.0 0.2 3.1 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.20 KII84852.1 - 1.7e-11 44.3 0.8 2.3e-11 43.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII84852.1 - 0.0011 18.8 0.1 0.002 17.9 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SBDS PF01172.13 KII84852.1 - 0.024 14.3 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein 3HCDH_N PF02737.13 KII84852.1 - 0.033 13.8 0.2 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pro_isomerase PF00160.16 KII84856.1 - 1.6e-46 158.3 0.2 1.8e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PIP5K PF01504.13 KII84857.1 - 4.4e-54 183.2 0.0 7.7e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase GMC_oxred_N PF00732.14 KII84858.1 - 4.4e-64 216.4 0.0 6.2e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII84858.1 - 8.2e-36 123.4 0.0 1.6e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KII84858.1 - 3.2e-05 23.0 0.1 4.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KII84858.1 - 0.00012 21.1 0.3 0.0014 17.5 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII84858.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII84858.1 - 0.019 14.0 0.1 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KII84858.1 - 0.087 11.7 0.6 0.32 9.8 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KII84858.1 - 0.2 10.0 0.8 0.31 9.4 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KII84858.1 - 0.21 10.3 0.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DIM1 PF02966.11 KII84859.1 - 1.2e-68 228.7 0.0 1.3e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KII84859.1 - 0.00049 19.7 0.1 0.00064 19.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KII84859.1 - 0.03 14.4 0.2 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like F-box-like PF12937.2 KII84860.1 - 3.2e-06 26.7 2.1 3.2e-06 26.7 1.5 1.9 2 0 0 2 2 2 1 F-box-like DUF2773 PF10971.3 KII84860.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) DUF2470 PF10615.4 KII84861.1 - 4.5e-12 46.0 0.0 7.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 KII84861.1 - 1.2e-09 38.0 3.0 2.2e-09 37.1 2.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.4 KII84863.1 - 2.5e-11 43.6 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 KII84863.1 - 7.1e-07 29.0 1.1 1.3e-06 28.2 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Pkinase PF00069.20 KII84864.1 - 0.05 12.7 0.0 0.39 9.8 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain Septin PF00735.13 KII84865.1 - 0.13 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Septin Rad60-SLD PF11976.3 KII84867.1 - 2.1e-22 78.6 0.1 2.8e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KII84867.1 - 9.6e-10 37.7 0.0 1.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HR1 PF02185.11 KII84868.1 - 0.0085 15.8 0.2 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Hr1 repeat Pkinase PF00069.20 KII84869.1 - 1.5e-10 40.6 0.0 3.7e-08 32.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.9 KII84869.1 - 4.9e-05 22.4 0.0 0.00012 21.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KII84869.1 - 7.8e-05 21.8 0.0 0.0028 16.7 0.0 2.0 1 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KII84869.1 - 0.00035 20.3 0.0 0.0029 17.3 0.0 2.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII84869.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.20 KII84870.1 - 2.4e-10 40.0 0.0 1.9e-08 33.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.9 KII84870.1 - 0.00027 20.0 0.0 0.00061 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII84870.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII84870.1 - 0.019 14.0 0.0 0.093 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 KII84873.1 - 7e-12 45.0 0.0 1.6e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KII84873.1 - 0.00021 20.4 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII84873.1 - 0.0019 17.9 0.2 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII84873.1 - 0.0062 15.6 0.0 0.099 11.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 KII84873.1 - 0.034 13.7 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.2 KII84874.1 - 4e-06 26.4 0.6 3.1e-05 23.6 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KII84874.1 - 0.0021 17.6 2.6 0.0051 16.4 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 KII84874.1 - 0.38 10.5 4.2 1 9.1 0.0 3.1 3 1 0 3 3 3 0 Leucine rich repeat 2OG-FeII_Oxy_2 PF13532.1 KII84875.1 - 7.4e-21 74.8 0.1 9.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KII84875.1 - 8.2e-06 26.0 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltrans PF00432.16 KII84876.1 - 6.6e-52 172.7 3.6 1.3e-10 40.6 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KII84876.1 - 5.1e-29 100.9 0.0 6.4e-13 49.0 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KII84876.1 - 8.5e-08 32.1 0.0 4.1e-05 23.5 0.0 3.1 1 1 2 3 3 3 2 Prenyltransferase-like F-box-like PF12937.2 KII84878.1 - 1.3e-05 24.8 0.4 0.00013 21.5 0.3 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KII84878.1 - 0.048 13.3 0.1 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 F-box domain Rhodanese PF00581.15 KII84879.1 - 3.5e-06 27.3 0.0 8.8e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 KII84880.1 - 8.3e-66 221.7 0.0 1.3e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84880.1 - 1.2e-35 122.8 0.0 5e-35 120.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII84880.1 - 5.6e-06 26.2 0.1 2.2e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KII84880.1 - 9.7e-06 24.7 0.3 1.7e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII84880.1 - 2.1e-05 23.6 0.0 0.00011 21.2 0.0 2.0 2 1 0 2 2 2 1 Kinase-like WaaY PF06176.6 KII84880.1 - 0.0038 16.4 0.4 0.0091 15.2 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KII84880.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KII84880.1 - 0.046 13.0 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 KII84880.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL KAAG1 PF15354.1 KII84880.1 - 0.14 12.5 1.9 10 6.5 0.2 2.9 2 0 0 2 2 2 0 Kidney-associated antigen 1 AA_permease_2 PF13520.1 KII84881.1 - 2.2e-70 237.3 52.4 2.6e-70 237.1 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII84881.1 - 5.6e-19 67.8 44.6 7.8e-19 67.3 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease CSTF_C PF14304.1 KII84883.1 - 0.076 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Pkinase PF00069.20 KII84884.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain SNF2_N PF00176.18 KII84885.1 - 6.4e-67 225.4 0.2 3.3e-66 223.1 0.0 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII84885.1 - 3.6e-15 55.5 0.0 1.2e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII84885.1 - 3.7e-09 36.6 0.1 3.7e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KII84885.1 - 0.0035 16.8 0.0 1 8.8 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase HDA2-3 PF11496.3 KII84885.1 - 0.0055 15.5 0.0 0.019 13.8 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Dicty_REP PF05086.7 KII84885.1 - 0.032 12.0 0.2 0.051 11.3 0.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3433 PF11915.3 KII84886.1 - 3.9e-19 68.5 5.4 3.9e-19 68.5 3.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF3433 PF11915.3 KII84887.1 - 1.7e-10 40.9 0.8 1.7e-10 40.9 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF455 PF04305.9 KII84888.1 - 1e-86 290.3 0.0 1.3e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KII84888.1 - 7.2e-08 31.9 0.2 1.4e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KII84888.1 - 0.0002 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Arabinose_Iso_C PF11762.3 KII84888.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain TauD PF02668.11 KII84889.1 - 1.9e-48 165.3 0.3 2.5e-48 165.0 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4527 PF15030.1 KII84889.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Aa_trans PF01490.13 KII84890.1 - 4.2e-32 111.1 35.4 4.9e-32 110.9 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPC12 PF06645.8 KII84893.1 - 1.3e-19 69.7 0.1 1.6e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ABC2_membrane_4 PF12730.2 KII84893.1 - 0.037 13.1 0.0 0.043 12.9 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Pkinase PF00069.20 KII84894.1 - 1.1e-71 241.1 0.0 2.7e-71 239.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84894.1 - 2.6e-37 128.2 0.1 1.1e-36 126.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KII84894.1 - 2e-15 55.9 0.0 3.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KII84894.1 - 2.4e-06 26.7 0.1 4.1e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII84894.1 - 0.00015 20.7 0.0 0.00047 19.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII84894.1 - 0.00027 20.7 0.1 0.005 16.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 KII84894.1 - 0.00059 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 KII84894.1 - 0.035 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.13 KII84896.1 - 8.7e-26 90.3 0.2 1.8e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII84896.1 - 6.7e-08 32.3 10.0 1.3e-07 31.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 KII84898.1 - 9.5 5.9 12.3 9.3 6.0 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.13 KII84899.1 - 1.1e-05 25.1 13.1 1.9e-05 24.4 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII84900.1 - 1.1e-15 57.1 1.0 1.8e-15 56.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CBFD_NFYB_HMF PF00808.18 KII84901.1 - 8.8e-10 38.5 0.2 1.8e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phosphodiest PF01663.17 KII84903.1 - 1.5e-12 47.5 0.3 1.5e-12 47.5 0.2 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KII84903.1 - 0.0013 18.1 0.0 0.0032 16.8 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.18 KII84903.1 - 0.0027 16.9 0.1 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Sulfatase RicinB_lectin_2 PF14200.1 KII84904.1 - 2.4e-15 56.7 0.0 5.1e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KII84904.1 - 0.00024 21.1 0.0 0.067 13.2 0.0 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KII84906.1 - 2.1e-27 95.5 7.3 7e-19 68.1 1.8 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KII84906.1 - 1.3e-05 25.2 3.5 0.032 14.2 0.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Pkinase_Tyr PF07714.12 KII84908.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_transf_15 PF01793.11 KII84909.1 - 2.5e-140 467.1 12.1 3.1e-140 466.8 8.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Baculo_VP91_N PF08475.5 KII84909.1 - 0.25 10.7 3.2 2.5 7.4 2.2 2.2 1 1 0 1 1 1 0 Viral capsid protein 91 N-terminal Acid_PPase PF12689.2 KII84910.1 - 7.2e-62 207.9 0.0 8.2e-62 207.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 KII84910.1 - 0.00068 19.3 0.0 0.00093 18.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KII84910.1 - 0.0035 17.5 0.8 0.015 15.4 0.0 2.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase RHH_3 PF12651.2 KII84910.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain Sec7_N PF12783.2 KII84914.1 - 1.8e-27 95.8 4.7 1.1e-25 90.0 4.2 3.0 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KII84914.1 - 3e-05 23.4 0.0 0.0015 18.0 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) EVC2_like PF12297.3 KII84914.1 - 0.14 10.7 0.1 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Bromodomain PF00439.20 KII84915.1 - 3.2e-20 71.8 0.0 7.8e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Fe_bilin_red PF05996.7 KII84915.1 - 0.009 15.5 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Homeobox PF00046.24 KII84916.1 - 1.3e-14 53.4 0.9 2.8e-14 52.4 0.6 1.6 1 0 0 1 1 1 1 Homeobox domain zf-RING_2 PF13639.1 KII84918.1 - 1e-09 38.0 10.9 1.6e-09 37.4 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII84918.1 - 8.1e-09 35.0 9.2 1.2e-08 34.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII84918.1 - 7.5e-08 32.2 10.0 1.1e-07 31.7 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII84918.1 - 1.3e-06 28.4 8.4 3.7e-06 26.9 5.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KII84918.1 - 1.5e-06 27.7 8.5 2.2e-06 27.2 5.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII84918.1 - 2.1e-06 27.2 5.6 3e-06 26.7 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII84918.1 - 0.0091 15.8 10.1 0.015 15.1 7.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KII84918.1 - 0.031 14.0 4.8 0.074 12.8 3.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KII84918.1 - 0.045 13.4 6.1 0.077 12.7 4.2 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KII84918.1 - 0.087 12.4 5.8 0.16 11.5 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KII84918.1 - 0.1 12.0 8.0 2.4 7.7 5.5 2.5 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 KII84918.1 - 0.6 9.9 3.7 1.2 8.9 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein C1_4 PF07975.7 KII84918.1 - 0.75 9.8 6.6 1.7 8.7 4.6 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain IBR PF01485.16 KII84918.1 - 4.6 7.1 9.3 22 4.9 6.4 2.1 1 1 0 1 1 1 0 IBR domain UPAR_LY6 PF00021.16 KII84919.1 - 2 8.8 13.0 7.1 7.1 1.7 3.3 1 1 2 3 3 3 0 u-PAR/Ly-6 domain Ank_2 PF12796.2 KII84920.1 - 2.3e-12 47.0 0.0 8.2e-11 42.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KII84920.1 - 5.2e-11 42.4 4.3 5.4e-09 36.0 0.5 3.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KII84920.1 - 2.1e-10 39.8 0.4 6.8e-08 31.9 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KII84920.1 - 6.3e-08 32.9 0.3 0.00024 21.5 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII84920.1 - 4.8e-06 26.3 0.0 0.00039 20.4 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Pyr_redox_2 PF07992.9 KII84921.1 - 4.5e-12 46.2 0.1 0.00093 19.1 0.0 3.5 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII84921.1 - 2.5e-11 43.8 0.9 5.8e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII84921.1 - 0.00019 20.4 1.7 1 8.2 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Eno-Rase_NADH_b PF12242.3 KII84921.1 - 0.0027 17.4 0.3 1.8 8.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase K_oxygenase PF13434.1 KII84921.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KII84921.1 - 0.036 12.7 0.8 10 4.6 0.0 3.1 4 0 0 4 4 4 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KII84921.1 - 0.13 12.3 0.8 24 4.8 0.1 3.5 2 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KII84921.1 - 0.25 11.2 6.2 0.13 12.1 0.3 2.8 3 0 0 3 3 3 0 short chain dehydrogenase MscS_porin PF12795.2 KII84923.1 - 6.8e-05 22.2 1.4 7.1e-05 22.2 1.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain IncA PF04156.9 KII84923.1 - 0.0016 18.0 0.3 0.0019 17.8 0.2 1.0 1 0 0 1 1 1 1 IncA protein DUF4398 PF14346.1 KII84923.1 - 0.0021 18.0 0.2 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) WEMBL PF05701.6 KII84923.1 - 0.0022 16.5 0.0 0.0024 16.4 0.0 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light OEP PF02321.13 KII84923.1 - 0.0099 15.4 1.6 0.02 14.4 1.1 1.5 1 1 0 1 1 1 1 Outer membrane efflux protein DUF1090 PF06476.7 KII84923.1 - 0.012 15.2 1.6 0.016 14.8 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) Myosin_tail_1 PF01576.14 KII84923.1 - 0.014 13.1 2.0 0.015 13.0 1.4 1.0 1 0 0 1 1 1 0 Myosin tail Tropomyosin PF00261.15 KII84923.1 - 0.016 14.3 0.4 0.02 13.9 0.3 1.3 1 0 0 1 1 1 0 Tropomyosin DUF4175 PF13779.1 KII84923.1 - 0.02 12.6 4.1 0.021 12.5 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Laminin_II PF06009.7 KII84923.1 - 0.025 14.3 0.7 0.033 13.9 0.5 1.1 1 0 0 1 1 1 0 Laminin Domain II Tropomyosin_1 PF12718.2 KII84923.1 - 0.026 14.3 1.2 0.035 13.9 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like PMEI PF04043.10 KII84923.1 - 0.039 13.8 0.6 0.045 13.6 0.4 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Reo_sigmaC PF04582.7 KII84923.1 - 0.04 13.0 0.3 0.048 12.8 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KII84923.1 - 0.042 12.5 0.2 0.043 12.4 0.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 KII84923.1 - 0.048 10.9 4.8 0.049 10.9 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.1 KII84923.1 - 0.05 12.7 0.4 0.057 12.5 0.3 1.0 1 0 0 1 1 1 0 Leucine zipper Baculo_PEP_C PF04513.7 KII84923.1 - 0.057 13.2 2.0 0.068 13.0 1.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.9 KII84923.1 - 0.089 12.0 7.2 0.12 11.6 5.0 1.2 1 0 0 1 1 1 0 Laminin Domain I YfdX PF10938.3 KII84923.1 - 0.14 11.8 3.5 0.32 10.6 2.4 1.6 1 1 0 1 1 1 0 YfdX protein DUF948 PF06103.6 KII84923.1 - 0.15 11.9 0.6 0.2 11.5 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2524 PF10732.4 KII84923.1 - 0.19 11.8 6.5 1.3 9.2 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DSX_dimer PF08828.5 KII84923.1 - 0.43 10.1 1.8 3.8 7.1 0.1 2.2 1 1 2 3 3 3 0 Doublesex dimerisation domain TarH PF02203.10 KII84923.1 - 0.84 9.4 4.7 0.91 9.3 3.1 1.3 1 1 0 1 1 1 0 Tar ligand binding domain homologue L27_N PF09060.5 KII84923.1 - 0.95 9.3 10.3 16 5.3 3.8 2.6 1 1 1 2 2 2 0 L27_N DUF2564 PF10819.3 KII84923.1 - 1.1 9.4 14.9 1.8 8.7 5.6 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) Chorion_1 PF01723.11 KII84924.1 - 0.072 12.9 0.3 0.085 12.7 0.2 1.1 1 0 0 1 1 1 0 Chorion protein TMEM169 PF15052.1 KII84926.1 - 1 9.2 11.0 1.5 8.6 0.1 2.8 1 1 2 3 3 3 0 TMEM169 protein family DUF1700 PF08006.6 KII84926.1 - 1.1 8.5 11.3 0.43 9.8 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Trep_Strep PF09605.5 KII84926.1 - 5 6.7 16.8 1.8 8.1 8.8 2.2 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4448 PF14610.1 KII84928.1 - 4.1e-16 59.0 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KII84928.1 - 5.9e-05 23.4 2.2 5.9e-05 23.4 1.5 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4126 PF13548.1 KII84928.1 - 1.1 8.7 5.3 0.24 10.8 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) PARP PF00644.15 KII84929.1 - 1.2e-08 34.6 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KII84929.1 - 1.4e-07 30.9 0.0 3.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII84929.1 - 0.0045 16.7 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic E2 family B zf-C2H2 PF00096.21 KII84930.1 - 5.6e-08 32.6 7.5 2.1e-05 24.5 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII84930.1 - 9.7e-06 25.6 9.8 0.0002 21.5 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII84930.1 - 1.1e-05 25.3 7.3 0.0027 17.9 1.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KII84930.1 - 2.8e-05 24.1 2.2 0.0032 17.5 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KII84930.1 - 0.0027 17.6 1.7 1.2 9.1 0.2 2.6 2 0 0 2 2 2 2 Zinc ribbon domain GAGA PF09237.6 KII84930.1 - 0.03 13.8 0.2 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 GAGA factor C1_4 PF07975.7 KII84930.1 - 0.042 13.8 2.0 2 8.4 0.1 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_3 PF14369.1 KII84930.1 - 0.13 12.2 1.3 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 zinc-finger zf-H2C2_5 PF13909.1 KII84930.1 - 0.13 12.5 3.4 0.15 12.3 1.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KII84930.1 - 0.43 10.5 3.7 0.86 9.6 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII84930.1 - 1.8 8.7 6.2 0.57 10.3 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GFA PF04828.9 KII84934.1 - 7.6e-21 73.8 0.7 1.1e-20 73.3 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KII84934.1 - 0.025 14.8 4.2 1.9 8.8 0.6 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.1 KII84934.1 - 0.03 13.9 0.1 0.03 13.9 0.1 2.5 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_6 PF14599.1 KII84934.1 - 0.042 13.6 0.7 4.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon zf-ribbon_3 PF13248.1 KII84934.1 - 0.25 10.5 0.1 0.25 10.5 0.1 2.1 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 KII84934.1 - 2 8.3 7.1 16 5.4 4.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.6 KII84934.1 - 3.3 7.3 9.2 0.95 9.0 0.2 2.7 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF1726 PF08351.6 KII84935.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DNA_mis_repair PF01119.14 KII84936.1 - 6e-19 67.6 0.0 1.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KII84936.1 - 5.8e-15 55.1 0.1 9.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KII84936.1 - 1.7e-13 50.2 0.3 4.4e-13 48.9 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KII84937.1 - 2.1e-21 76.0 0.1 6.4e-21 74.4 0.0 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain FmdA_AmdA PF03069.10 KII84938.1 - 1.9e-50 171.5 0.0 1.7e-24 86.2 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family G-alpha PF00503.15 KII84939.1 - 5.4e-114 380.9 0.0 6.3e-114 380.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII84939.1 - 8.7e-13 47.8 0.1 3.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KII84939.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KII84939.1 - 0.028 13.8 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SNARE_assoc PF09335.6 KII84940.1 - 3.7e-15 56.2 5.2 3.7e-15 56.2 3.6 1.9 1 1 0 1 1 1 1 SNARE associated Golgi protein DNA_binding_1 PF01035.15 KII84941.1 - 3e-25 87.7 0.1 3.7e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Nup84_Nup100 PF04121.8 KII84942.1 - 3.7e-87 292.6 0.0 9.9e-87 291.2 0.0 1.6 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 TPR_14 PF13428.1 KII84942.1 - 1.2 9.9 5.8 0.58 10.9 0.3 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat Solute_trans_a PF03619.11 KII84943.1 - 1.5e-69 234.4 16.4 1.7e-69 234.1 11.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2101 PF09874.4 KII84943.1 - 0.27 10.6 11.6 0.057 12.8 0.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) SNARE_assoc PF09335.6 KII84944.1 - 1.6e-15 57.4 5.9 1.6e-15 57.4 4.1 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3671 PF12420.3 KII84944.1 - 0.37 10.7 5.4 2.6 8.0 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF3753 PF12575.3 KII84944.1 - 0.99 9.2 3.4 7.4 6.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) SNARE_assoc PF09335.6 KII84945.1 - 1e-14 54.8 6.7 1e-14 54.8 4.7 1.8 1 1 0 1 1 1 1 SNARE associated Golgi protein DUF3671 PF12420.3 KII84945.1 - 0.11 12.4 2.8 0.57 10.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function zf-DHHC PF01529.15 KII84945.1 - 0.79 9.0 3.6 8.4 5.7 2.5 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase PLDc PF00614.17 KII84949.1 - 2.4e-16 58.9 3.2 2.5e-09 36.6 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KII84949.1 - 3.8e-14 52.5 0.3 1.5e-07 31.2 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain Rotamase_3 PF13616.1 KII84949.1 - 0.013 15.7 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain Abhydrolase_6 PF12697.2 KII84950.1 - 9.7e-20 71.4 1.2 1.1e-19 71.1 0.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII84950.1 - 1.8e-05 24.5 0.1 6.3e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2 PF00096.21 KII84952.1 - 0.0044 17.2 1.6 0.023 15.0 1.1 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII84952.1 - 5.9 7.4 7.0 1.1 9.7 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger CMAS PF02353.15 KII84953.1 - 3.4e-64 216.5 0.0 7.7e-64 215.3 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KII84953.1 - 1.7e-11 44.1 0.0 4e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII84953.1 - 6.1e-11 42.9 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII84953.1 - 9.9e-08 32.3 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII84953.1 - 3.5e-07 29.9 0.0 5.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII84953.1 - 3.8e-06 27.2 0.0 8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII84953.1 - 8.6e-06 26.0 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII84953.1 - 2.6e-05 23.6 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KII84953.1 - 3.3e-05 23.5 0.0 5.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KII84953.1 - 4.4e-05 23.4 0.0 7.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII84953.1 - 0.0012 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KII84953.1 - 0.0027 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KII84953.1 - 0.0038 16.8 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 KII84953.1 - 0.021 13.5 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 KII84953.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 KII84953.1 - 0.076 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4448 PF14610.1 KII84954.1 - 0.019 14.4 0.1 3.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) MFS_2 PF13347.1 KII84954.1 - 0.029 12.7 1.8 0.037 12.4 1.3 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein HAMP PF00672.20 KII84955.1 - 2.2e-48 162.3 21.5 9.5e-09 35.3 0.0 8.2 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 KII84955.1 - 2.9e-28 97.8 1.4 1.2e-27 95.7 0.1 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KII84955.1 - 5.4e-23 81.1 0.5 2.2e-22 79.1 0.4 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KII84955.1 - 1.4e-17 63.4 1.1 7.1e-17 61.1 0.8 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AcylCoA_dehyd_C PF12186.3 KII84955.1 - 0.095 12.5 9.5 24 4.8 0.1 5.9 6 1 0 6 6 6 0 Acyl-CoA dehydrogenase C terminal Syntaxin PF00804.20 KII84955.1 - 0.25 11.5 3.9 12 6.0 0.2 4.4 3 2 0 3 3 3 0 Syntaxin DUF1824 PF08854.5 KII84956.1 - 0.083 12.5 0.1 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) DUF1212 PF06738.7 KII84961.1 - 1.4e-40 138.8 6.4 1.8e-39 135.2 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KII84961.1 - 4.1e-17 62.3 7.5 4.1e-17 62.3 5.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Hepatitis_core PF00906.15 KII84962.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Hepatitis core antigen Hepatitis_core PF00906.15 KII84963.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Hepatitis core antigen PI-PLC-X PF00388.14 KII84963.1 - 0.089 12.1 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_1 PF00036.27 KII84964.1 - 0.0028 16.8 0.0 0.048 12.9 0.0 3.0 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 KII84964.1 - 0.0035 17.1 0.0 0.067 13.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KII84964.1 - 0.0097 16.0 0.1 0.45 10.6 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KII84964.1 - 0.052 12.9 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 0 EF hand HSCB_C PF07743.8 KII84964.1 - 0.13 12.7 4.3 0.76 10.2 0.2 3.8 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain HrcA PF01628.16 KII84964.1 - 0.7 9.4 5.0 6.8 6.2 0.2 3.1 2 1 0 3 3 3 0 HrcA protein C terminal domain TFIIB PF00382.14 KII84965.1 - 1.9e-35 120.5 1.1 4.6e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KII84965.1 - 9.7e-24 83.4 11.2 8.9e-23 80.3 1.3 2.5 2 0 0 2 2 2 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 KII84965.1 - 3.3e-07 29.4 3.1 7.4e-07 28.3 2.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KII84965.1 - 5.8e-07 29.1 0.6 0.037 13.5 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 KII84965.1 - 0.041 13.3 3.8 0.082 12.4 2.6 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 KII84965.1 - 0.055 12.9 2.1 0.1 12.1 1.5 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 KII84965.1 - 0.13 12.0 0.3 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.1 KII84965.1 - 0.21 11.3 1.5 8.2 6.2 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal BLVR PF06375.6 KII84965.1 - 1.8 8.3 14.8 0.37 10.6 4.1 2.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) FLO_LFY PF01698.11 KII84965.1 - 3.6 6.3 6.5 4.3 6.0 0.5 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein F-box-like PF12937.2 KII84966.1 - 0.0004 20.0 0.3 0.00099 18.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII84966.1 - 0.14 11.7 0.0 12 5.6 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KII84967.1 - 2.9e-09 36.5 1.9 9.4e-08 31.6 0.2 2.8 2 0 0 2 2 2 2 F-box-like DUF1672 PF07901.6 KII84968.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Transp_cyt_pur PF02133.10 KII84969.1 - 3.1e-89 299.5 37.4 3.6e-89 299.3 25.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2530 PF10745.4 KII84969.1 - 0.02 14.8 0.5 0.02 14.8 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) zf-MYND PF01753.13 KII84970.1 - 5.1e-09 35.8 7.8 1.2e-08 34.7 5.4 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KII84971.1 - 1.8e-07 30.8 5.7 1.8e-07 30.8 4.0 2.4 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.1 KII84971.1 - 0.57 10.0 3.9 0.22 11.4 0.9 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Prenyltrans PF00432.16 KII84972.1 - 2.3e-36 123.0 9.1 2.8e-07 29.9 0.1 6.3 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KII84972.1 - 5.9e-22 78.1 0.0 1.3e-17 64.2 0.0 3.5 2 2 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KII84972.1 - 2.2e-06 27.6 0.0 5.2e-05 23.2 0.0 2.8 2 1 1 3 3 3 2 Prenyltransferase-like F-box-like PF12937.2 KII84973.1 - 0.00037 20.1 0.1 0.00086 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 KII84976.1 - 0.0023 17.1 0.0 0.0097 15.0 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII84976.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Colicin_C PF12106.3 KII84976.1 - 0.13 11.8 0.6 0.7 9.5 0.0 2.5 3 0 0 3 3 3 0 Colicin C terminal ribonuclease domain UAA PF08449.6 KII84977.1 - 9.2e-65 218.5 1.3 2.1e-64 217.3 0.9 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KII84977.1 - 2.5e-09 37.2 22.9 6.4e-08 32.6 4.8 4.3 3 2 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 KII84977.1 - 0.0012 19.0 7.4 0.0012 19.0 5.1 3.8 4 1 0 5 5 5 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 KII84977.1 - 0.0022 17.1 2.0 0.097 11.7 0.3 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 KII84977.1 - 0.0061 16.2 6.0 0.0061 16.2 4.2 2.9 2 2 0 2 2 2 1 Triose-phosphate Transporter family Sugar_tr PF00083.19 KII84980.1 - 1.4e-110 369.9 25.7 1.6e-110 369.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII84980.1 - 1.2e-20 73.5 34.4 1.2e-20 73.5 23.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DEAD PF00270.24 KII84981.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII84981.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit BTB PF00651.26 KII84982.1 - 0.00029 20.7 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Copper-bind PF00127.15 KII84983.1 - 0.0014 18.7 0.0 0.004 17.3 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family FixG_C PF11614.3 KII84983.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase HMG_box PF00505.14 KII84985.1 - 3.2e-10 40.1 0.2 3.6e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII84985.1 - 0.0024 18.1 0.0 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain Saccharop_dh PF03435.13 KII84986.1 - 3.7e-109 365.2 0.0 1.9e-108 362.9 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 KII84986.1 - 9.2e-91 303.1 0.0 1.6e-90 302.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 KII84986.1 - 8.5e-08 32.3 0.3 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_26 PF13659.1 KII84986.1 - 8e-06 25.8 0.0 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KII84986.1 - 5.4e-05 23.6 0.1 0.051 14.0 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KII84986.1 - 0.00014 22.4 0.0 0.0023 18.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 KII84986.1 - 0.0015 18.6 0.6 0.004 17.1 0.4 1.8 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII84986.1 - 0.014 15.3 0.2 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KII84986.1 - 0.018 15.3 0.8 0.076 13.3 0.1 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain MTS PF05175.9 KII84986.1 - 0.026 13.9 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain GFO_IDH_MocA PF01408.17 KII84986.1 - 0.034 14.6 0.1 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_11 PF08241.7 KII84986.1 - 0.036 14.5 0.0 1.5 9.3 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain DREV PF05219.7 KII84986.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Vps39_2 PF10367.4 KII84988.1 - 2.5 8.3 7.5 2.9 8.1 5.2 1.3 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Fz PF01392.17 KII84990.1 - 0.085 13.2 1.2 0.24 11.7 0.7 1.6 2 0 0 2 2 2 0 Fz domain Spermine_synth PF01564.12 KII84993.1 - 4e-89 297.7 0.0 6.9e-89 296.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Saccharop_dh PF03435.13 KII84993.1 - 2.8e-84 283.3 0.0 2.9e-83 280.0 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KII84993.1 - 3e-08 33.8 0.1 4.6e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.1 KII84993.1 - 2.5e-05 23.8 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII84993.1 - 0.00013 22.3 0.1 0.13 12.7 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KII84993.1 - 0.0007 20.1 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 KII84993.1 - 0.0012 18.8 0.3 0.0027 17.7 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding GFO_IDH_MocA PF01408.17 KII84993.1 - 0.0015 19.0 0.1 0.13 12.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KII84993.1 - 0.016 15.5 1.0 0.064 13.5 0.1 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KII84993.1 - 0.028 14.3 0.2 0.028 14.3 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DREV PF05219.7 KII84993.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ldh_1_N PF00056.18 KII84993.1 - 0.067 13.0 0.1 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain MTS PF05175.9 KII84993.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain KR PF08659.5 KII84993.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 KR domain Glyco_hydro_92 PF07971.7 KII84997.1 - 5.5e-28 97.8 0.0 6.1e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.7 KII84999.1 - 1.9e-151 505.1 1.8 2.4e-151 504.8 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Lactococcin PF04369.8 KII84999.1 - 0.0095 15.8 0.0 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 Lactococcin-like family TRAM1 PF08390.6 KII84999.1 - 0.45 10.0 1.7 0.96 8.9 1.2 1.5 1 0 0 1 1 1 0 TRAM1-like protein PCNA_N PF00705.13 KII85000.1 - 5.6e-54 181.0 3.9 5.6e-54 181.0 2.7 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KII85000.1 - 8.6e-40 135.6 0.0 1.7e-18 66.7 0.0 3.0 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KII85000.1 - 2.3e-05 23.6 0.0 5.7e-05 22.3 0.0 1.7 2 1 0 2 2 2 1 Rad9 Hus1 PF04005.7 KII85000.1 - 0.037 12.9 4.6 0.61 8.9 0.0 2.8 4 0 0 4 4 4 0 Hus1-like protein Nop14 PF04147.7 KII85000.1 - 0.086 10.7 19.0 0.037 11.9 11.8 1.4 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.7 KII85000.1 - 0.18 11.0 13.7 0.33 10.1 9.5 1.4 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.24 KII85002.1 - 5.8e-56 188.3 0.0 3.5e-43 146.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KII85002.1 - 9.2e-19 67.2 0.0 2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KII85002.1 - 1.4e-11 44.7 2.4 7.1e-05 22.8 0.1 4.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KII85002.1 - 6.8e-08 32.7 0.3 0.031 14.4 0.0 4.2 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KII85002.1 - 9.4e-07 29.6 0.0 0.016 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KII85002.1 - 3.6e-06 26.6 0.0 0.081 12.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KII85002.1 - 5.3e-06 26.0 0.2 0.026 14.2 0.1 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KII85002.1 - 2.8e-05 24.0 0.0 0.074 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KII85002.1 - 4.3e-05 22.6 0.0 0.0025 16.9 0.0 3.0 4 0 0 4 4 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KII85002.1 - 5.2e-05 22.9 0.1 0.07 12.7 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_5 PF07728.9 KII85002.1 - 0.00023 20.9 0.1 0.71 9.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KII85002.1 - 0.00035 19.4 0.1 0.12 11.0 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus DUF2075 PF09848.4 KII85002.1 - 0.00046 19.2 0.0 0.24 10.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KII85002.1 - 0.00058 19.7 0.0 0.078 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KII85002.1 - 0.0011 19.2 0.0 0.64 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KII85002.1 - 0.0014 17.5 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 KII85002.1 - 0.0016 17.6 0.0 0.86 8.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KII85002.1 - 0.0018 17.4 0.1 0.77 8.8 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KII85002.1 - 0.0019 18.1 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KII85002.1 - 0.002 18.3 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KII85002.1 - 0.0026 17.2 4.1 13 5.1 0.1 4.8 3 2 2 5 5 5 0 AAA domain NTPase_1 PF03266.10 KII85002.1 - 0.0059 16.3 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.12 KII85002.1 - 0.0067 15.8 0.1 0.78 9.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_31 PF13614.1 KII85002.1 - 0.0078 16.1 0.1 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KII85002.1 - 0.0099 15.4 0.0 1.1 8.8 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KII85002.1 - 0.011 15.2 0.0 0.011 15.2 0.0 3.1 4 0 0 4 4 3 0 AAA domain Herpes_Helicase PF02689.9 KII85002.1 - 0.012 13.4 0.0 0.018 12.8 0.0 1.1 1 0 0 1 1 1 0 Helicase Arch_ATPase PF01637.13 KII85002.1 - 0.014 15.1 0.0 4.9 6.7 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase Molydop_binding PF01568.16 KII85002.1 - 0.014 15.2 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain AAA_24 PF13479.1 KII85002.1 - 0.021 14.4 0.2 6.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KII85002.1 - 0.027 14.7 0.0 9.6 6.5 0.0 3.2 2 1 0 3 3 3 0 ABC transporter UPF0079 PF02367.12 KII85002.1 - 0.03 13.9 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 KII85002.1 - 0.039 13.8 0.1 0.48 10.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase cobW PF02492.14 KII85002.1 - 0.059 12.8 0.1 8 5.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KII85002.1 - 0.059 12.9 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 KII85002.1 - 0.061 11.9 0.0 0.83 8.2 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Cytidylate_kin2 PF13189.1 KII85002.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase-like family MobB PF03205.9 KII85002.1 - 0.09 12.4 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 KII85002.1 - 0.1 12.2 0.1 1.4 8.5 0.0 2.6 3 0 0 3 3 2 0 Adenylylsulphate kinase Bac_DnaA PF00308.13 KII85002.1 - 0.11 12.0 0.1 13 5.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein DUF815 PF05673.8 KII85002.1 - 0.15 10.9 0.0 5.3 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) zf-MYND PF01753.13 KII85003.1 - 1e-09 38.0 14.2 2.4e-09 36.8 9.9 1.6 1 0 0 1 1 1 1 MYND finger Thioredoxin PF00085.15 KII85007.1 - 3.7e-59 196.8 0.0 1.9e-28 98.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KII85007.1 - 4.6e-19 68.8 0.2 1.1e-18 67.6 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KII85007.1 - 8e-18 64.6 0.1 1.3e-07 31.7 0.1 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII85007.1 - 2.6e-11 43.5 0.1 0.0011 19.0 0.0 4.4 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KII85007.1 - 1.6e-10 40.8 0.0 0.00053 19.9 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KII85007.1 - 5e-07 29.4 0.0 0.017 14.7 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KII85007.1 - 8.4e-05 22.1 0.3 0.081 12.4 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KII85007.1 - 0.00029 20.3 1.7 0.28 10.7 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_4 PF13462.1 KII85007.1 - 0.0011 18.9 1.3 1.4 8.9 0.1 3.1 3 1 0 3 3 3 2 Thioredoxin TraF PF13728.1 KII85007.1 - 0.0074 15.7 0.1 1.7 8.1 0.0 2.5 3 0 0 3 3 3 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 KII85007.1 - 0.014 15.3 1.9 0.39 10.7 0.1 3.1 2 2 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.1 KII85007.1 - 0.019 15.1 0.0 5.9 7.1 0.0 2.9 3 1 0 3 3 3 0 Transposase DDE domain Exo_endo_phos PF03372.18 KII85008.1 - 3.5e-08 33.6 0.0 4.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rifin_STEVOR PF02009.11 KII85009.1 - 1.1 8.8 6.0 1.4 8.4 4.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Alpha-amylase PF00128.19 KII85010.1 - 9.6e-26 90.9 0.0 3.4e-25 89.0 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.5 KII85010.1 - 0.0078 16.0 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.11 KII85010.1 - 0.12 10.1 0.3 4.7 4.8 0.0 2.9 3 1 0 3 3 3 0 Glycosyl hydrolase family 70 Sugar_tr PF00083.19 KII85011.1 - 1.7e-80 270.8 22.8 1.9e-80 270.6 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII85011.1 - 2.9e-26 92.0 50.6 3.5e-23 81.9 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KII85011.1 - 0.00017 19.9 2.3 0.00017 19.9 1.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KII85011.1 - 0.00035 19.1 0.5 0.00035 19.1 0.4 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Reo_sigmaC PF04582.7 KII85012.1 - 1.5 7.9 7.4 0.41 9.7 1.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NAD_binding_6 PF08030.7 KII85014.1 - 1.4e-20 73.7 0.0 1.7e-12 47.5 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KII85014.1 - 8e-15 55.0 10.9 8e-15 55.0 7.6 2.6 3 2 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KII85014.1 - 2.3e-14 53.1 0.0 5.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 KII85014.1 - 0.019 15.1 9.9 0.22 11.6 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B_N PF00033.14 KII85014.1 - 1.8 7.8 25.0 0.045 13.1 3.4 2.9 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Acetyltransf_3 PF13302.1 KII85015.1 - 8.7e-09 35.6 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII85015.1 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KII85015.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MbeD_MobD PF04899.7 KII85016.1 - 0.018 14.9 0.2 1.4 8.8 0.2 2.7 2 0 0 2 2 2 0 MbeD/MobD like EF-hand_6 PF13405.1 KII85016.1 - 0.057 13.3 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain DUF1664 PF07889.7 KII85016.1 - 0.06 13.1 1.8 2.4 7.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Frag1 PF10277.4 KII85017.1 - 0.01 15.3 2.7 0.011 15.2 1.9 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family MFS_1 PF07690.11 KII85019.1 - 9.6e-21 73.8 40.4 1.5e-18 66.6 14.0 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily DUF3270 PF11674.3 KII85019.1 - 0.17 11.9 0.8 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Sad1_UNC PF07738.8 KII85020.1 - 5.9e-24 84.3 0.0 8.2e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Tropomyosin_1 PF12718.2 KII85020.1 - 0.014 15.2 4.1 0.014 15.2 2.8 2.1 1 1 1 2 2 2 0 Tropomyosin like Mu-like_Pro PF10123.4 KII85020.1 - 0.035 13.5 4.3 0.047 13.1 3.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein Abhydrolase_1 PF00561.15 KII85021.1 - 1e-30 107.0 0.0 3.5e-30 105.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII85021.1 - 8.7e-27 94.4 0.0 1.4e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII85021.1 - 4.1e-14 52.5 0.0 4.4e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII85021.1 - 0.00038 19.7 0.0 0.74 9.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.9 KII85021.1 - 0.004 15.6 0.0 0.0055 15.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KII85021.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Ser_hydrolase PF06821.8 KII85021.1 - 0.059 12.9 0.1 0.51 9.9 0.1 2.3 2 1 0 2 2 2 0 Serine hydrolase Peptidase_S28 PF05577.7 KII85021.1 - 0.073 11.6 0.0 0.22 10.0 0.0 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase S28 CRAL_TRIO PF00650.15 KII85022.1 - 8.9e-32 109.7 0.0 1.3e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KII85022.1 - 1.2e-11 44.5 0.1 3.1e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Cpn60_TCP1 PF00118.19 KII85023.1 - 4e-142 474.2 0.2 4.6e-142 474.0 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.23 KII85024.1 - 1.4e-42 145.3 1.1 1.8e-42 145.0 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-MYND PF01753.13 KII85025.1 - 6.6e-12 45.1 17.7 1.5e-11 43.9 12.3 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KII85025.1 - 0.3 10.7 12.1 0.68 9.6 8.4 1.6 1 0 0 1 1 1 0 HIT zinc finger Utp14 PF04615.8 KII85027.1 - 1.8 6.6 23.2 1.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Utp14 protein Cep57_CLD PF14073.1 KII85029.1 - 0.018 14.8 2.6 0.018 14.8 1.8 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 SAPS PF04499.10 KII85029.1 - 0.11 11.0 2.8 0.33 9.5 1.2 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Vmethyltransf_C PF08456.5 KII85029.1 - 0.17 11.3 2.5 0.26 10.6 1.7 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal MIF4G PF02854.14 KII85031.1 - 6.3e-26 91.0 0.1 1.4e-25 89.9 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KII85031.1 - 3.1e-19 68.7 0.4 1.1e-17 63.7 0.0 3.1 4 0 0 4 4 4 1 MA3 domain Cnd1_N PF12922.2 KII85031.1 - 0.051 13.2 2.1 0.76 9.3 1.4 2.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Methyltransf_18 PF12847.2 KII85032.1 - 3e-16 59.9 0.0 4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII85032.1 - 2.3e-15 56.5 0.0 3.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII85032.1 - 1.4e-07 31.8 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII85032.1 - 3.8e-07 30.1 0.0 9.7e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII85032.1 - 8.5e-06 25.2 0.0 1.7e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KII85032.1 - 1.9e-05 24.4 0.0 0.00011 22.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII85032.1 - 0.00016 22.1 0.0 0.0007 20.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII85032.1 - 0.00016 21.9 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KII85032.1 - 0.0015 18.1 0.0 0.0031 17.0 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rsm22 PF09243.5 KII85032.1 - 0.0018 17.4 0.0 0.043 12.8 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.1 KII85032.1 - 0.028 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KII85032.1 - 0.079 12.0 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DnaJ PF00226.26 KII85033.1 - 8.2e-06 25.4 0.1 1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KII85033.1 - 0.0026 17.5 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 AAA_12 PF13087.1 KII85034.1 - 1.6e-28 99.5 0.0 4.5e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII85034.1 - 1.2e-24 87.2 1.9 3.9e-13 49.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KII85034.1 - 7.5e-15 55.0 0.0 3e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KII85034.1 - 3.2e-10 39.6 0.0 1.2e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KII85034.1 - 3e-06 26.9 0.1 0.057 12.9 0.0 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KII85034.1 - 0.00016 20.9 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.9 KII85034.1 - 0.0016 18.1 0.2 0.044 13.4 0.0 2.5 2 0 0 2 2 2 1 Helicase ResIII PF04851.10 KII85034.1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 KII85034.1 - 0.0079 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KII85034.1 - 0.009 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII85034.1 - 0.012 15.7 0.1 0.04 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 KII85034.1 - 0.018 15.2 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KII85034.1 - 0.037 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 KII85034.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KII85034.1 - 0.042 13.1 0.2 0.33 10.2 0.0 2.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.1 KII85034.1 - 0.042 14.1 1.0 0.092 13.0 0.0 2.0 3 0 0 3 3 2 0 AAA domain Flavi_DEAD PF07652.9 KII85034.1 - 0.065 12.9 0.2 0.35 10.6 0.0 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_33 PF13671.1 KII85034.1 - 0.067 13.0 0.1 0.22 11.3 0.1 1.9 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KII85034.1 - 0.079 11.9 0.0 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KII85034.1 - 0.1 13.4 1.2 0.34 11.7 0.8 2.1 1 1 0 1 1 1 0 AAA domain RAP1 PF07218.6 KII85035.1 - 1.4 6.9 12.2 1.6 6.7 8.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PPC PF04151.10 KII85035.1 - 2.4 9.2 6.9 5.1 8.1 4.8 1.7 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Citrate_synt PF00285.16 KII85036.1 - 1e-104 350.1 0.0 1.2e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase AAA_12 PF13087.1 KII85037.1 - 1.1e-13 51.0 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII85038.1 - 2.1e-24 86.4 0.1 2.4e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KII85038.1 - 1.2e-14 54.3 0.0 6e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII85038.1 - 2.2e-12 46.5 0.1 1.1e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KII85038.1 - 6.9e-05 22.4 0.1 0.029 13.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KII85038.1 - 8.5e-05 22.7 0.1 0.00061 19.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KII85038.1 - 0.00013 21.2 0.1 0.003 16.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.17 KII85038.1 - 0.00018 20.4 0.0 0.00038 19.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.1 KII85038.1 - 0.00024 21.5 0.1 0.03 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KII85038.1 - 0.00049 20.8 0.0 0.0014 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KII85038.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KII85038.1 - 0.0013 18.3 0.1 0.006 16.2 0.0 2.0 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.1 KII85038.1 - 0.0014 18.6 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KII85038.1 - 0.0021 17.9 0.1 0.0063 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KII85038.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KII85038.1 - 0.0037 17.4 0.0 0.008 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KII85038.1 - 0.0048 16.4 0.1 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Arch_ATPase PF01637.13 KII85038.1 - 0.0059 16.3 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 KII85038.1 - 0.0092 14.9 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KII85038.1 - 0.011 15.2 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Flavi_NS1 PF00948.16 KII85038.1 - 0.016 13.6 0.0 0.026 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 AAA_25 PF13481.1 KII85038.1 - 0.017 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KII85038.1 - 0.038 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 KII85038.1 - 0.048 12.6 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KII85038.1 - 0.06 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KII85038.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KII85038.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_12 PF13087.1 KII85038.1 - 0.089 12.1 0.1 0.58 9.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain DUF2713 PF10897.3 KII85038.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Pcc1 PF09341.5 KII85039.1 - 1.4e-18 66.6 0.3 1.6e-18 66.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Adeno_PV PF03910.8 KII85039.1 - 0.11 11.5 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Peptidase_M24 PF00557.19 KII85040.1 - 5.1e-22 78.4 0.2 6.9e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GnsAB PF08178.6 KII85040.1 - 3.4 7.3 5.8 12 5.6 0.2 3.0 2 1 0 2 2 2 0 GnsA/GnsB family DUF4316 PF14195.1 KII85040.1 - 3.6 7.7 7.4 53 3.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Methyltransf_11 PF08241.7 KII85041.1 - 3.8e-11 43.3 0.0 7.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII85041.1 - 4.6e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII85041.1 - 1.4e-09 37.4 0.0 2.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KII85041.1 - 2.7e-09 36.9 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII85041.1 - 7.8e-08 32.7 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII85041.1 - 3.2e-07 30.6 0.0 5.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII85041.1 - 5.6e-07 29.2 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII85041.1 - 4.1e-05 22.7 0.0 0.00013 21.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_15 PF09445.5 KII85041.1 - 0.00052 19.6 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.14 KII85041.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KII85041.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII85041.1 - 0.0036 16.6 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KII85041.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KII85041.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 KII85041.1 - 0.022 14.3 0.0 0.32 10.6 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase FmrO PF07091.6 KII85041.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) NDUF_B8 PF05821.6 KII85042.1 - 9.5e-08 31.8 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) FdsD PF11390.3 KII85042.1 - 0.2 11.8 0.3 0.32 11.1 0.2 1.3 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD XPG_N PF00752.12 KII85043.1 - 3.5e-29 101.0 0.0 1.1e-28 99.4 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KII85043.1 - 5.4e-26 90.4 0.0 1.4e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KII85043.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing PH PF00169.24 KII85044.1 - 0.15 12.3 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 0 PH domain PBP1_TM PF14812.1 KII85044.1 - 0.86 9.9 7.7 5.6 7.3 5.3 2.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KII85044.1 - 1.1 9.5 7.3 2.5 8.3 5.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KII85044.1 - 1.4 8.3 7.1 2.7 7.4 4.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin CtaG_Cox11 PF04442.9 KII85045.1 - 3.3e-54 182.7 0.0 4.4e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.26 KII85046.1 - 5.1e-17 61.3 1.4 1.5e-16 59.8 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain Sporozoite_P67 PF05642.6 KII85047.1 - 0.71 7.6 7.4 0.86 7.3 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSP1_C PF07462.6 KII85047.1 - 2.3 6.4 3.9 3.5 5.9 2.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1767 PF08585.7 KII85048.1 - 4e-08 33.4 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Carn_acyltransf PF00755.15 KII85049.1 - 7.7e-135 450.2 0.0 9.1e-135 450.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PcrB PF01884.12 KII85049.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 PcrB family AAA_11 PF13086.1 KII85050.1 - 6.7e-26 91.3 0.8 5.1e-15 55.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.1 KII85050.1 - 1.1e-18 67.3 0.0 1.5e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KII85050.1 - 2.2e-14 53.5 0.0 3.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII85050.1 - 1e-10 41.1 0.0 2.5e-10 39.9 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KII85050.1 - 7.7e-07 29.2 0.0 2.3e-06 27.7 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain Helicase_RecD PF05127.9 KII85050.1 - 2.6e-05 23.9 0.0 9.1e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Helicase ResIII PF04851.10 KII85050.1 - 0.00068 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KII85050.1 - 0.00094 18.7 0.1 0.0031 17.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KII85050.1 - 0.0011 18.3 0.0 0.034 13.4 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.12 KII85050.1 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 KII85050.1 - 0.0014 17.8 0.1 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.4 KII85050.1 - 0.0021 17.0 0.0 0.0096 14.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 KII85050.1 - 0.0028 17.4 0.0 0.0055 16.4 0.0 1.5 2 0 0 2 2 1 1 Archaeal ATPase AAA_22 PF13401.1 KII85050.1 - 0.0029 17.7 0.0 0.013 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KII85050.1 - 0.014 14.9 0.1 0.056 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KII85050.1 - 0.016 14.4 0.1 0.037 13.2 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 KII85050.1 - 0.02 15.0 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KII85050.1 - 0.045 13.3 0.1 0.28 10.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Herpes_ori_bp PF02399.10 KII85050.1 - 0.065 11.1 0.0 0.1 10.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Rad17 PF03215.10 KII85050.1 - 0.079 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2541 PF10807.3 KII85050.1 - 0.094 12.4 0.0 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) DUF3638 PF12340.3 KII85050.1 - 0.098 11.6 0.2 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) Zot PF05707.7 KII85050.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Viral_helicase1 PF01443.13 KII85050.1 - 0.11 11.9 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 KII85050.1 - 0.11 11.4 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase TrwB_AAD_bind PF10412.4 KII85050.1 - 0.14 10.7 0.1 0.25 9.9 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 KII85050.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KII85050.1 - 0.17 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 KII85050.1 - 0.17 10.7 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KII85050.1 - 0.18 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Med26 PF08711.6 KII85051.1 - 1.2e-09 37.4 0.0 3.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Seadorna_VP6 PF07407.6 KII85051.1 - 0.073 11.8 0.2 0.098 11.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Phosphonate-bd PF12974.2 KII85053.1 - 1.1e-06 28.2 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 KII85053.1 - 2.7e-05 23.5 0.0 4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 KII85053.1 - 7.1e-05 22.5 0.0 9.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KII85053.1 - 0.0037 16.6 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Yip1 PF04893.12 KII85054.1 - 5.4e-13 48.8 18.5 7.7e-13 48.3 12.9 1.2 1 0 0 1 1 1 1 Yip1 domain AAA PF00004.24 KII85055.1 - 7.1e-42 142.7 0.0 1.2e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII85055.1 - 2.1e-06 27.9 0.1 0.00037 20.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KII85055.1 - 4.5e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KII85055.1 - 4.7e-05 22.4 0.0 8.4e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KII85055.1 - 9.5e-05 22.1 0.2 0.00059 19.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KII85055.1 - 0.00021 21.3 0.1 0.0017 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KII85055.1 - 0.00058 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KII85055.1 - 0.004 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KII85055.1 - 0.0046 16.5 0.1 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KII85055.1 - 0.0053 15.8 0.1 0.16 11.1 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.1 KII85055.1 - 0.0063 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII85055.1 - 0.0065 16.2 0.2 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KII85055.1 - 0.0067 17.2 0.8 0.015 16.1 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KII85055.1 - 0.008 16.4 0.3 0.033 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KII85055.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 KII85055.1 - 0.01 15.7 0.2 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KII85055.1 - 0.013 14.8 0.4 0.78 9.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KII85055.1 - 0.027 14.1 0.1 0.43 10.2 0.1 2.4 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 KII85055.1 - 0.035 12.9 0.0 0.082 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 KII85055.1 - 0.052 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 KII85055.1 - 0.069 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 KII85055.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Viral_helicase1 PF01443.13 KII85055.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 KII85055.1 - 0.099 12.5 0.4 4 7.2 0.0 2.6 3 0 0 3 3 2 0 Shikimate kinase RNA_helicase PF00910.17 KII85055.1 - 0.1 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KII85055.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KII85055.1 - 0.15 11.6 0.2 0.4 10.2 0.2 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KII85056.1 - 6.2e-09 35.8 1.3 2e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KII85056.1 - 1.7e-06 27.3 0.1 1.7e-06 27.3 0.0 2.7 3 1 1 4 4 3 1 AIG1 family AAA_29 PF13555.1 KII85056.1 - 0.00016 21.1 0.1 0.068 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 KII85056.1 - 0.0002 20.3 4.2 0.027 13.3 0.1 2.7 1 1 1 2 2 2 2 Type II/IV secretion system protein FeoB_N PF02421.13 KII85056.1 - 0.00032 20.0 0.0 0.0011 18.2 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KII85056.1 - 0.0011 18.2 1.6 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 KII85056.1 - 0.0011 17.9 0.1 0.0011 17.9 0.0 3.0 2 1 1 3 3 3 1 Septin ABC_tran PF00005.22 KII85056.1 - 0.0026 18.0 17.8 0.0031 17.8 0.0 3.8 3 2 0 3 3 3 1 ABC transporter Dynamin_N PF00350.18 KII85056.1 - 0.0054 16.5 0.2 0.0054 16.5 0.1 4.7 3 2 1 4 4 3 2 Dynamin family AAA_24 PF13479.1 KII85056.1 - 0.016 14.7 1.7 3.4 7.2 0.1 2.5 1 1 1 2 2 2 0 AAA domain IIGP PF05049.8 KII85056.1 - 0.03 13.1 0.0 0.03 13.1 0.0 3.2 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Peptidase_M14 PF00246.19 KII85056.1 - 0.031 13.9 0.7 0.053 13.1 0.5 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase SRPRB PF09439.5 KII85056.1 - 0.038 13.2 0.0 0.038 13.2 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit MobB PF03205.9 KII85056.1 - 0.044 13.4 3.1 0.73 9.5 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KII85056.1 - 0.07 12.6 0.9 3.5 7.1 0.1 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KII85056.1 - 0.089 12.2 0.0 0.089 12.2 0.0 3.6 3 1 0 3 3 2 0 FtsK/SpoIIIE family Miro PF08477.8 KII85056.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.3 3 1 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 KII85056.1 - 0.13 13.1 14.2 3.9 8.3 4.4 3.6 2 1 0 2 2 2 0 AAA domain ACCA PF03255.9 KII85056.1 - 0.24 10.9 7.7 0.81 9.2 0.0 2.9 2 1 1 3 3 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3752 PF12572.3 KII85056.1 - 0.32 11.1 23.1 0.55 10.3 16.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Exonuc_VII_L PF02601.10 KII85056.1 - 0.58 9.2 16.8 0.85 8.7 11.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_18 PF13238.1 KII85056.1 - 0.67 10.2 0.0 0.67 10.2 0.0 4.0 3 1 0 3 3 2 0 AAA domain ApoLp-III PF07464.6 KII85056.1 - 0.82 9.6 20.1 1.3 8.9 14.0 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DEAD PF00270.24 KII85056.1 - 1.4 8.3 5.6 6.6 6.1 0.2 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KII85056.1 - 1.6 8.8 9.8 2.2 8.4 0.2 3.5 3 2 0 3 3 3 0 AAA domain V_ATPase_I PF01496.14 KII85056.1 - 1.7 6.4 11.4 2.2 6.0 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family His_Phos_2 PF00328.17 KII85056.1 - 2 7.6 10.2 3.7 6.7 5.2 1.9 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) DUF3829 PF12889.2 KII85056.1 - 3.1 6.8 16.4 5.5 6.1 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2317 PF10079.4 KII85056.1 - 4.3 5.8 18.5 6.1 5.3 12.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) cobW PF02492.14 KII85056.1 - 6.5 6.1 9.9 1.5 8.2 0.2 3.4 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KII85056.1 - 7.2 5.9 7.8 2.1 7.7 1.1 3.2 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain OmpH PF03938.9 KII85056.1 - 7.5 6.4 33.1 1.3e+02 2.4 22.4 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SRP54 PF00448.17 KII85056.1 - 7.8 5.8 8.8 10 5.4 0.4 3.4 3 1 1 4 4 4 0 SRP54-type protein, GTPase domain Asp-B-Hydro_N PF05279.6 KII85056.1 - 7.8 6.2 22.3 12 5.6 15.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MMR_HSR1 PF01926.18 KII85057.1 - 7.7e-07 29.0 0.0 1.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KII85057.1 - 0.0018 17.3 0.0 0.0018 17.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 KII85057.1 - 0.0024 17.0 0.6 0.0072 15.5 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KII85057.1 - 0.028 14.2 0.0 0.028 14.2 0.0 3.5 2 2 1 3 3 3 0 Dynamin family FeoB_N PF02421.13 KII85057.1 - 0.029 13.6 0.4 0.69 9.1 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 KII85057.1 - 0.03 13.3 0.1 0.24 10.3 0.1 2.3 1 1 0 1 1 1 0 Septin DUF342 PF03961.8 KII85057.1 - 0.068 11.5 5.1 0.089 11.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tox-PL PF15644.1 KII85057.1 - 2.3 8.9 4.7 3 8.6 0.8 2.5 2 1 0 2 2 2 0 Papain fold toxin 1 APG6 PF04111.7 KII85057.1 - 3.8 6.4 17.3 5.7 5.8 12.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Apolipoprotein PF01442.13 KII85057.1 - 4.1 6.8 24.0 8.6 5.8 16.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain OmpH PF03938.9 KII85057.1 - 4.6 7.1 27.2 81 3.1 18.9 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MAT1 PF06391.8 KII85057.1 - 8.1 5.9 16.6 5.7 6.4 10.4 1.5 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ING PF12998.2 KII85057.1 - 8.7 6.6 12.7 26 5.1 7.0 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2 PF00096.21 KII85061.1 - 5.4e-12 45.3 14.0 0.00032 20.8 0.5 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII85061.1 - 4.5e-11 42.4 17.1 9.7e-06 25.6 0.2 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII85061.1 - 2.2e-10 40.0 12.9 0.0018 18.4 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KII85061.1 - 0.00047 20.2 3.6 0.89 9.8 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KII85061.1 - 0.01 15.7 2.1 1 9.3 0.0 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-TRAF PF02176.13 KII85061.1 - 0.022 15.1 6.0 0.049 14.0 1.6 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met2 PF12907.2 KII85061.1 - 0.075 13.0 1.6 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-binding IBR PF01485.16 KII85061.1 - 0.099 12.5 7.3 0.84 9.5 1.6 2.2 1 1 1 2 2 2 0 IBR domain RRN7 PF11781.3 KII85061.1 - 0.53 9.8 3.6 3.9 7.0 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC PF01530.13 KII85061.1 - 1.5 8.6 10.0 0.97 9.2 2.8 3.2 2 1 0 2 2 2 0 Zinc finger, C2HC type zf-C2H2_jaz PF12171.3 KII85061.1 - 1.6 8.9 9.8 6.5 7.0 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RAI1 PF08652.6 KII85063.1 - 5.7e-21 74.0 0.0 9.4e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease ORC6 PF05460.8 KII85063.1 - 6.9 5.6 7.7 2.3 7.2 1.0 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF2054 PF10218.4 KII85064.1 - 0.007 16.2 3.9 0.0085 15.9 2.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) TPR_12 PF13424.1 KII85066.1 - 8.7e-39 131.3 29.7 3e-09 36.6 0.1 4.5 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 KII85066.1 - 2.2e-18 64.6 18.5 0.058 13.3 0.1 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat SNAP PF14938.1 KII85066.1 - 5.8e-18 65.0 12.9 7.1e-10 38.5 1.3 3.2 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KII85066.1 - 2.5e-14 52.6 16.5 3.8e-05 23.2 0.2 6.3 4 2 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 KII85066.1 - 7.6e-12 45.5 11.7 0.0031 18.1 0.0 7.1 3 1 4 8 8 8 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 KII85066.1 - 2.5e-11 42.5 3.2 0.0025 17.0 0.0 5.7 5 0 0 5 5 5 2 SHNi-TPR TPR_10 PF13374.1 KII85066.1 - 6e-11 41.8 4.4 0.49 10.4 0.1 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KII85066.1 - 4.2e-10 38.7 17.7 0.0011 18.4 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KII85066.1 - 1.1e-05 25.5 14.3 0.054 13.6 0.9 5.3 2 1 5 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KII85066.1 - 1.5e-05 24.4 15.8 0.046 13.5 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat Vps5 PF09325.5 KII85066.1 - 5.1e-05 22.6 7.4 0.0041 16.4 0.4 3.8 2 1 1 3 3 3 2 Vps5 C terminal like DUF1876 PF08962.6 KII85066.1 - 6.6e-05 22.6 0.0 2.5 7.9 0.0 4.5 2 2 3 5 5 5 1 Domain of unknown function (DUF1876) TPR_7 PF13176.1 KII85066.1 - 0.00027 20.5 2.7 0.62 10.0 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII85066.1 - 0.00042 20.6 18.8 0.42 10.9 2.1 6.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.4 KII85066.1 - 0.0032 17.4 11.3 0.71 9.8 1.2 4.5 2 1 0 3 3 3 1 Tetratricopeptide repeat HsbA PF12296.3 KII85066.1 - 0.0055 16.5 1.0 0.13 12.1 0.1 3.2 2 1 1 3 3 2 1 Hydrophobic surface binding protein A Peripla_BP_2 PF01497.13 KII85066.1 - 0.015 14.4 2.9 0.14 11.2 0.1 2.8 3 0 0 3 3 3 0 Periplasmic binding protein TPR_3 PF07720.7 KII85066.1 - 0.016 15.0 1.4 0.11 12.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.1 KII85066.1 - 0.016 15.1 1.1 0.49 10.3 0.0 3.5 2 1 1 3 3 3 0 AAA ATPase domain TPR_17 PF13431.1 KII85066.1 - 0.037 14.2 8.0 45 4.6 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII85066.1 - 0.064 13.7 16.7 34 5.1 0.0 7.5 6 1 1 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.4 KII85066.1 - 0.065 12.6 6.2 3 7.1 0.1 3.5 1 1 1 3 3 3 0 26S proteasome subunit RPN7 MitMem_reg PF13012.1 KII85066.1 - 0.072 13.1 0.5 1.4 8.9 0.1 3.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF1978 PF09321.5 KII85066.1 - 0.29 10.5 3.9 5.6 6.3 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1978) Snf7 PF03357.16 KII85066.1 - 1 8.7 4.7 2.1 7.7 0.2 2.8 1 1 2 3 3 3 0 Snf7 Toxin_3 PF00537.13 KII85067.1 - 0.67 9.8 5.4 2 8.3 3.7 1.9 1 1 0 1 1 1 0 Scorpion toxin-like domain CFEM PF05730.6 KII85067.1 - 3 7.7 12.3 6.4 6.6 5.1 2.8 2 1 0 2 2 2 0 CFEM domain Whi5 PF08528.6 KII85069.1 - 0.00021 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Whi5 like IGF2_C PF08365.6 KII85070.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Pkinase PF00069.20 KII85071.1 - 4.9e-05 22.6 0.0 8.7e-05 21.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain MLANA PF14991.1 KII85071.1 - 0.14 12.1 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A SUR7 PF06687.7 KII85072.1 - 3.3e-11 43.1 16.6 2.4e-06 27.2 0.3 2.0 1 1 1 2 2 2 2 SUR7/PalI family Sugar_tr PF00083.19 KII85074.1 - 2.1e-108 362.8 29.9 2.4e-108 362.6 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII85074.1 - 5.1e-24 84.6 35.3 5.1e-24 84.6 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 KII85075.1 - 9e-68 229.3 0.0 1.1e-67 229.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KII85075.1 - 5.1e-08 33.0 0.1 4.3e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 KII85075.1 - 0.056 12.0 0.1 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 Serine carboxypeptidase S28 ECH PF00378.15 KII85076.1 - 1.9e-31 109.0 0.0 2.1e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TauD PF02668.11 KII85078.1 - 3.3e-49 167.8 0.8 4.1e-49 167.5 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MIT PF04212.13 KII85079.1 - 0.014 15.2 0.6 0.033 14.0 0.3 1.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KII85079.1 - 0.018 14.6 0.7 0.031 13.9 0.5 1.4 1 0 0 1 1 1 0 TPR repeat TPR_21 PF09976.4 KII85079.1 - 0.059 13.3 1.5 0.14 12.0 1.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII85079.1 - 0.11 12.4 0.7 0.24 11.4 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GATA PF00320.22 KII85081.1 - 7.3e-15 54.0 3.6 1.5e-14 52.9 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger PRiA4_ORF3 PF07929.6 KII85084.1 - 1.1e-26 93.3 0.0 1.7e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 KII85084.1 - 4.2e-12 45.7 9.1 6.9e-12 45.0 6.3 1.4 1 0 0 1 1 1 1 MYND finger Actin PF00022.14 KII85085.1 - 1.3e-44 152.2 0.0 5.4e-43 146.9 0.0 2.7 1 1 0 1 1 1 1 Actin IncA PF04156.9 KII85087.1 - 0.19 11.3 7.0 0.78 9.2 5.0 1.9 1 1 1 2 2 2 0 IncA protein Mito_carr PF00153.22 KII85088.1 - 9.9e-58 191.8 0.3 5.4e-22 77.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_16 PF10294.4 KII85089.1 - 4.9e-20 71.6 0.0 8.3e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KII85089.1 - 0.033 13.7 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Arrestin_N PF00339.24 KII85090.1 - 1.4e-07 31.4 2.0 0.00018 21.3 1.2 3.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 KII85090.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 DEAD PF00270.24 KII85091.1 - 6e-19 68.1 0.0 9.7e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII85091.1 - 1.1e-18 66.8 0.0 4.4e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII85091.1 - 2.1e-06 27.6 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KII85091.1 - 0.0022 16.8 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Arrestin_N PF00339.24 KII85093.1 - 8e-06 25.7 0.0 0.00014 21.7 0.0 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Nucleoporin_FG PF13634.1 KII85094.1 - 2.3e-27 95.4 114.0 3.6e-13 49.7 24.7 3.5 1 1 2 3 3 3 3 Nucleoporin FG repeat region AceK PF06315.6 KII85094.1 - 0.059 11.6 1.3 0.083 11.1 0.9 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) CorA PF01544.13 KII85094.1 - 0.18 10.8 0.7 0.27 10.2 0.1 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein USP8_interact PF08941.5 KII85095.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 USP8 interacting Mitofilin PF09731.4 KII85096.1 - 1.9e-114 383.4 2.5 2.3e-114 383.1 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Dicistro_VP4 PF11492.3 KII85096.1 - 0.88 9.6 5.6 12 5.9 0.1 3.9 4 0 0 4 4 4 0 Cricket paralysis virus, VP4 ATG22 PF11700.3 KII85097.1 - 5e-121 404.4 24.4 5.7e-121 404.2 16.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF962 PF06127.6 KII85097.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Trehalase PF01204.13 KII85098.1 - 1.1e-166 555.4 0.0 1.4e-166 555.1 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KII85098.1 - 2e-12 46.1 0.0 3.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Bundlin PF05307.6 KII85098.1 - 0.064 13.1 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bundlin Lipase_3 PF01764.20 KII85099.1 - 3.8e-08 33.0 0.0 5e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 KII85099.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ctf8 PF09696.5 KII85100.1 - 5.5e-19 68.1 0.0 8.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Ctf8 KAR9 PF08580.5 KII85102.1 - 0.74 8.0 3.5 0.65 8.1 2.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 F-box-like PF12937.2 KII85103.1 - 6.5e-11 41.7 1.3 8.9e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like DUF4611 PF15387.1 KII85103.1 - 0.13 12.4 3.1 0.31 11.2 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KII85103.1 - 4.4 6.8 8.9 8.7 5.8 6.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Phage_tail_T PF06223.7 KII85106.1 - 0.14 12.5 0.6 0.38 11.1 0.4 1.6 1 0 0 1 1 1 0 Minor tail protein T Methyltransf_28 PF02636.12 KII85108.1 - 2.8e-67 226.7 0.0 3.5e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.13 KII85109.1 - 1.7e-85 285.1 0.3 1.7e-85 285.1 0.2 1.5 2 0 0 2 2 2 1 eIF-6 family AhpC-TSA_2 PF13911.1 KII85110.1 - 2.2e-15 56.5 0.0 3.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KII85110.1 - 5.1e-10 39.0 0.0 9.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII85110.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin F-box-like PF12937.2 KII85111.1 - 0.00017 21.2 0.0 0.00047 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII85111.1 - 0.085 12.5 0.4 52 3.6 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 KII85111.1 - 0.99 10.0 8.1 4.9 7.8 0.2 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat Kelch_4 PF13418.1 KII85112.1 - 4.2e-30 103.2 15.0 2.3e-10 40.0 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KII85112.1 - 5.3e-19 67.8 25.4 8.9e-07 28.9 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KII85112.1 - 4e-18 64.7 12.4 2e-06 27.7 0.0 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KII85112.1 - 9.2e-18 63.8 7.0 1e-05 25.3 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KII85112.1 - 1.2e-14 53.5 0.2 2.8e-05 23.5 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 KII85112.1 - 8.1e-11 41.2 9.4 9.5e-05 22.0 0.3 5.7 6 0 0 6 6 6 2 Kelch motif SKG6 PF08693.5 KII85112.1 - 0.0064 15.7 0.0 0.0064 15.7 0.0 2.8 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Bac_rhamnosid PF05592.6 KII85113.1 - 2.4e-27 95.3 0.9 4.9e-27 94.3 0.7 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KII85113.1 - 0.0002 20.2 0.8 0.00037 19.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 KII85113.1 - 0.00028 19.6 0.2 0.00041 19.1 0.2 1.2 1 0 0 1 1 1 1 Trehalase Aa_trans PF01490.13 KII85114.1 - 1.9e-81 273.6 34.2 2.2e-81 273.4 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_trans_1_3 PF13528.1 KII85116.1 - 4.7e-05 22.7 0.0 9.3e-05 21.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 1 PTPlike_phytase PF14566.1 KII85117.1 - 2.5e-121 400.8 0.0 4e-40 137.2 0.0 3.7 4 0 0 4 4 4 3 Inositol hexakisphosphate Y_phosphatase PF00102.22 KII85117.1 - 3.4e-06 26.5 0.0 0.011 15.1 0.0 3.3 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.15 KII85117.1 - 6.3e-05 22.5 0.0 0.67 9.5 0.0 4.3 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain TFIIE-A_C-term PF11521.3 KII85117.1 - 0.00016 21.5 0.0 1.5 8.8 0.0 3.5 3 0 0 3 3 3 2 C-terminal general transcription factor TFIIE alpha VSP PF03302.8 KII85118.1 - 0.00051 18.8 11.0 0.00074 18.2 7.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein CD99L2 PF12301.3 KII85118.1 - 0.044 13.4 5.0 0.15 11.6 3.5 2.0 1 1 0 1 1 1 0 CD99 antigen like protein 2 VTC PF09359.5 KII85119.1 - 6.6e-95 317.3 0.0 1.3e-94 316.3 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KII85119.1 - 1e-21 77.9 19.5 2.5e-21 76.6 6.5 3.3 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KII85119.1 - 4.4e-09 36.4 4.1 5.7e-09 36.0 2.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Clc-like PF07062.7 KII85119.1 - 0.073 12.3 0.4 0.14 11.4 0.3 1.4 1 0 0 1 1 1 0 Clc-like Gtr1_RagA PF04670.7 KII85120.1 - 2.6e-53 180.5 0.0 3.4e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KII85120.1 - 2e-05 23.8 0.0 3.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KII85120.1 - 0.0039 16.4 0.0 0.0069 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KII85120.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII85120.1 - 0.021 14.5 0.1 0.16 11.6 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 KII85120.1 - 0.033 14.6 0.0 0.088 13.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein DUF566 PF04484.7 KII85120.1 - 0.47 9.9 5.3 0.7 9.3 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) F-box-like PF12937.2 KII85121.1 - 1.7e-08 34.0 1.4 6.1e-08 32.2 1.0 2.0 1 0 0 1 1 1 1 F-box-like CTP_transf_2 PF01467.21 KII85122.1 - 0.091 12.8 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylyltransferase GMC_oxred_N PF00732.14 KII85123.1 - 8.6e-73 245.0 0.0 1.2e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII85123.1 - 1.6e-37 129.0 0.3 2.7e-37 128.2 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KII85123.1 - 3e-06 26.3 0.8 0.0017 17.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KII85123.1 - 5.2e-05 22.3 0.1 0.00029 19.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII85123.1 - 0.0002 20.4 0.4 0.00035 19.6 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KII85123.1 - 0.00032 20.6 0.2 0.0012 18.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII85123.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KII85123.1 - 0.17 10.3 0.2 0.26 9.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein RhoGAP PF00620.22 KII85124.1 - 5.1e-38 130.0 0.0 7.7e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 KII85124.1 - 0.0011 17.8 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Phe_ZIP PF08916.6 KII85124.1 - 0.078 13.3 0.0 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Phenylalanine zipper Glyco_hydro_17 PF00332.13 KII85125.1 - 9.8e-10 37.9 6.6 5.1e-09 35.5 0.7 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Drf_GBD PF06371.8 KII85126.1 - 1.1e-14 54.2 0.1 1.5e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF823 PF05689.6 KII85126.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Fungal_trans_2 PF11951.3 KII85127.1 - 1.8e-51 174.9 0.2 4e-51 173.7 0.0 1.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85127.1 - 2.1e-05 24.3 8.8 2.1e-05 24.3 6.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KII85128.1 - 1.1e-34 119.6 1.3 1.8e-34 118.9 0.9 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85128.1 - 0.00012 21.9 8.7 0.00023 20.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.24 KII85129.1 - 7.3e-31 106.4 0.1 9.6e-18 64.3 0.2 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KII85129.1 - 5.8e-16 58.7 7.8 2.5e-07 30.9 2.8 4.1 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 KII85129.1 - 2.9e-09 36.7 0.2 9.6e-05 22.2 0.1 3.8 3 1 0 3 3 3 2 PH domain PH_8 PF15409.1 KII85129.1 - 5.2e-07 29.6 2.0 3.9e-05 23.6 0.2 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 KII85129.1 - 0.00013 22.1 0.1 0.27 11.4 0.3 2.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_4 PF15404.1 KII85129.1 - 0.028 13.9 0.1 0.7 9.4 0.0 2.8 2 1 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.2 KII85129.1 - 0.029 14.2 5.2 1 9.3 0.0 2.9 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.5 KII85129.1 - 0.088 12.7 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Plant pleckstrin homology-like region ACBP PF00887.14 KII85130.1 - 2.6e-31 107.1 0.9 3.8e-31 106.5 0.6 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Tachystatin_B PF11478.3 KII85132.1 - 0.31 10.8 2.1 0.55 10.0 0.3 2.3 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B DAO PF01266.19 KII85133.1 - 1.2e-08 34.2 0.2 4.2e-05 22.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII85133.1 - 4.2e-08 32.7 0.5 4.7e-05 22.6 0.1 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KII85133.1 - 2.2e-07 30.2 0.0 4.8e-06 25.8 0.0 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KII85133.1 - 5.6e-07 29.4 0.6 1.3e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII85133.1 - 7.1e-05 21.8 0.1 0.00026 19.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KII85133.1 - 0.0012 18.7 0.1 0.0058 16.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII85133.1 - 0.0025 18.1 0.3 0.012 16.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII85133.1 - 0.021 13.3 0.1 0.036 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KII85133.1 - 0.11 11.5 0.2 0.28 10.2 0.1 1.6 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KII85133.1 - 0.13 11.3 2.5 0.1 11.6 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KII85133.1 - 0.31 9.8 0.7 0.49 9.1 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Acyl_transf_1 PF00698.16 KII85134.1 - 5.6e-67 226.3 0.2 2.7e-64 217.5 0.0 3.6 4 0 0 4 4 4 1 Acyl transferase domain DUF1729 PF08354.5 KII85134.1 - 1.2e-29 101.8 1.3 1e-28 98.8 0.6 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KII85134.1 - 4.9e-27 93.7 0.1 1.9e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.21 KII85134.1 - 7.4e-27 94.4 0.1 1.9e-26 93.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KII85134.1 - 4.7e-20 72.3 0.0 1e-19 71.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KII85134.1 - 8.9e-15 54.5 0.0 2.3e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KII85134.1 - 1.1e-13 51.0 0.0 3.4e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.1 KII85134.1 - 3.1e-13 49.6 0.1 1.7e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Thiolase_N PF00108.18 KII85134.1 - 0.013 14.4 0.1 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain F-box-like PF12937.2 KII85135.1 - 1.5e-08 34.2 0.5 1.5e-08 34.2 0.3 2.9 3 0 0 3 3 3 1 F-box-like TPR_11 PF13414.1 KII85136.1 - 3.4e-16 58.6 15.6 4.8e-12 45.3 4.4 3.9 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 KII85136.1 - 2.2e-08 33.3 11.0 0.022 14.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KII85136.1 - 1.9e-05 24.4 1.4 0.32 11.3 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII85136.1 - 0.00012 21.6 15.9 0.18 11.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII85136.1 - 0.0024 18.4 5.3 0.0024 18.4 3.7 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII85136.1 - 0.0026 18.0 11.9 0.013 15.8 2.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII85136.1 - 0.013 16.0 7.4 3.5 8.5 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KII85136.1 - 0.046 13.5 3.3 0.087 12.6 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KII85136.1 - 0.13 12.3 2.5 0.84 9.8 1.6 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KII85136.1 - 0.18 11.6 5.9 4.8 7.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KII85136.1 - 5 7.1 10.3 1.8 8.5 1.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 KII85137.1 - 2.1e-17 62.6 1.2 4.3e-17 61.6 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KII85137.1 - 2.4e-08 33.7 0.1 3.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain CTDII PF01556.13 KII85139.1 - 6.4e-20 70.8 0.5 1.4e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KII85139.1 - 4e-13 48.8 0.0 6.6e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF202 PF02656.10 KII85140.1 - 1.1e-08 35.1 2.7 1.1e-08 35.1 1.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Transcrip_reg PF01709.15 KII85141.1 - 2.5e-60 203.5 0.0 2.8e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Amidase PF01425.16 KII85142.1 - 5.6e-82 275.9 0.0 8.9e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 Amidase eIF-5a PF01287.15 KII85142.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold zf-MYND PF01753.13 KII85143.1 - 2.2e-07 30.6 9.3 4.1e-07 29.7 6.5 1.5 1 0 0 1 1 1 1 MYND finger NYN PF01936.13 KII85144.1 - 4e-19 69.3 0.0 6.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 NYN domain zf-C2H2 PF00096.21 KII85145.1 - 1.2e-08 34.7 10.1 0.00018 21.6 3.5 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII85145.1 - 7.4e-07 29.0 14.2 0.0011 19.1 3.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII85145.1 - 2.4 8.6 17.2 0.086 13.1 5.3 2.9 3 1 0 3 3 3 0 Zinc-finger double domain zf-MYND PF01753.13 KII85146.1 - 2e-07 30.7 10.6 3.1e-07 30.1 7.3 1.3 1 0 0 1 1 1 1 MYND finger His_Phos_2 PF00328.17 KII85147.1 - 2.9e-38 132.1 0.0 3.4e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NUDIX PF00293.23 KII85148.1 - 9.3e-13 47.9 0.4 1.4e-12 47.3 0.3 1.3 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.17 KII85149.1 - 5.9e-49 166.7 18.2 1.4e-46 158.9 12.6 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter PrgI PF12666.2 KII85149.1 - 2.3 8.4 6.0 46 4.2 0.0 3.7 2 1 0 3 3 3 0 PrgI family protein Rep_fac_C PF08542.6 KII85150.1 - 5.2e-21 74.4 0.0 1.8e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KII85150.1 - 3.6e-13 49.4 0.0 7.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KII85150.1 - 2.7e-06 27.6 0.1 6.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 KII85150.1 - 8.3e-05 22.1 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KII85150.1 - 0.00096 19.1 0.8 0.032 14.2 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 KII85150.1 - 0.0028 16.4 0.0 0.0049 15.6 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KII85150.1 - 0.0041 17.2 1.8 0.044 13.9 0.7 2.7 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KII85150.1 - 0.0064 15.9 0.1 0.025 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 KII85150.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KII85150.1 - 0.033 14.2 0.3 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KII85150.1 - 0.074 12.1 0.0 0.25 10.4 0.0 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 KII85150.1 - 0.078 11.7 0.3 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain HD PF01966.17 KII85151.1 - 0.00013 21.9 0.2 0.0015 18.5 0.1 2.2 1 1 0 1 1 1 1 HD domain WD40 PF00400.27 KII85153.1 - 2.5e-26 90.5 7.9 5.8e-07 29.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KII85153.1 - 0.054 11.6 0.2 0.13 10.4 0.1 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Glyco_hydro_10 PF00331.15 KII85154.1 - 1.7e-95 319.7 0.0 1.9e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KII85154.1 - 5.9e-13 48.2 11.8 5.9e-13 48.2 8.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_10 PF00331.15 KII85155.1 - 3.3e-96 322.0 0.0 3.7e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PEX11 PF05648.9 KII85156.1 - 6.4e-12 45.2 0.0 1.8e-10 40.5 0.0 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GST_N PF02798.15 KII85157.1 - 9.2e-18 64.1 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KII85157.1 - 2.9e-16 59.4 0.0 4.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII85157.1 - 6.2e-14 51.7 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII85157.1 - 5.2e-12 45.5 0.0 7.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII85157.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII85157.1 - 0.0067 16.8 0.0 0.0086 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans_2 PF11951.3 KII85158.1 - 1.4e-28 99.6 1.4 1.8e-28 99.2 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85158.1 - 1.3e-05 25.0 10.1 3.4e-05 23.6 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KII85159.1 - 8.3e-24 83.9 40.7 1.7e-23 82.9 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.16 KII85160.1 - 1.8e-82 277.5 0.0 2.4e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF4176 PF13780.1 KII85160.1 - 0.075 12.7 0.2 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) eIF-5a PF01287.15 KII85160.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold GMC_oxred_N PF00732.14 KII85161.1 - 6.5e-63 212.6 0.0 8.5e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII85161.1 - 2e-39 135.1 0.0 3.5e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KII85161.1 - 0.00041 19.3 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KII85161.1 - 0.063 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LrgB PF04172.11 KII85162.1 - 0.025 13.7 5.2 0.013 14.6 1.7 2.0 2 1 1 3 3 3 0 LrgB-like family MerC PF03203.9 KII85162.1 - 0.07 13.5 1.8 0.14 12.5 1.3 1.5 1 0 0 1 1 1 0 MerC mercury resistance protein PrgI PF12666.2 KII85162.1 - 0.098 12.8 4.3 0.16 12.0 2.0 2.0 1 1 0 1 1 1 0 PrgI family protein eIF3_subunit PF08597.5 KII85163.1 - 4.8e-52 176.9 18.6 5.3e-52 176.8 12.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit COQ9 PF08511.6 KII85164.1 - 3.6e-11 42.4 0.0 6.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 COQ9 DEAD PF00270.24 KII85166.1 - 3.6e-35 120.9 0.3 8.5e-35 119.7 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII85166.1 - 2.8e-24 84.7 0.2 6.9e-24 83.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KII85166.1 - 0.0073 16.4 0.2 0.098 12.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 KII85166.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_19 PF13245.1 KII85166.1 - 0.032 13.9 0.2 0.92 9.3 0.0 2.6 2 1 0 2 2 2 0 Part of AAA domain CMS1 PF14617.1 KII85166.1 - 0.048 12.7 0.1 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 KII85166.1 - 0.086 12.4 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain TPP_enzyme_C PF02775.16 KII85166.1 - 0.092 12.3 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain F-box-like PF12937.2 KII85167.1 - 1.3e-10 40.8 0.6 3.8e-10 39.3 0.4 1.9 1 0 0 1 1 1 1 F-box-like DUF1860 PF08949.5 KII85167.1 - 0.18 11.3 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Mrr_N PF14338.1 KII85170.1 - 0.025 14.6 0.4 0.053 13.5 0.3 1.5 1 0 0 1 1 1 0 Mrr N-terminal domain Nop14 PF04147.7 KII85170.1 - 1.4 6.7 10.1 2 6.2 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KII85170.1 - 6.2 4.7 7.8 9.6 4.0 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 KII85170.1 - 9.8 5.9 12.3 5.2 6.8 7.1 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TEA PF01285.13 KII85172.1 - 1.7e-10 40.6 0.0 1.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family HLH PF00010.21 KII85173.1 - 9.4e-08 31.6 0.0 2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain THUMP PF02926.12 KII85174.1 - 1.3e-08 34.8 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Cwf_Cwc_15 PF04889.7 KII85174.1 - 0.058 13.1 0.2 0.082 12.6 0.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CBP PF12192.3 KII85174.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Fungal calcium binding protein F_actin_cap_B PF01115.12 KII85176.1 - 1.5e-101 338.6 0.0 1.8e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pro_isomerase PF00160.16 KII85177.1 - 6.7e-47 159.5 0.0 7.8e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.15 KII85178.1 - 3.1e-135 450.8 0.0 3.8e-135 450.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII85178.1 - 2.1e-14 53.1 0.5 7.1e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KII85178.1 - 2.7e-05 23.6 0.1 0.0054 16.1 0.0 2.4 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 KII85178.1 - 0.00077 18.6 0.8 0.76 8.8 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KII85178.1 - 0.0039 16.6 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain YozD PF14162.1 KII85178.1 - 0.099 12.7 0.0 0.34 11.0 0.0 1.8 1 1 1 2 2 2 0 YozD-like protein Methyltransf_23 PF13489.1 KII85179.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KII85179.1 - 0.02 14.2 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 KII85179.1 - 0.032 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KII85179.1 - 0.099 13.0 0.0 0.29 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KII85179.1 - 0.16 12.4 0.0 0.66 10.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain ATP_synt_H PF05493.8 KII85180.1 - 2.4e-20 72.3 5.5 2.8e-20 72.1 3.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 KII85180.1 - 0.0046 16.3 2.4 0.0054 16.1 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF420 PF04238.7 KII85180.1 - 0.017 15.1 0.3 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Exosortase_EpsH PF09721.5 KII85180.1 - 0.028 13.6 2.6 0.03 13.5 1.8 1.0 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) COX7a PF02238.10 KII85180.1 - 0.088 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa ARL6IP6 PF15062.1 KII85180.1 - 0.11 12.4 0.4 0.18 11.6 0.1 1.5 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix DUF1145 PF06611.7 KII85180.1 - 0.19 11.3 4.8 7.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Claudin_2 PF13903.1 KII85180.1 - 0.19 11.3 1.3 0.2 11.3 0.9 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4173 PF13777.1 KII85180.1 - 1.3 8.3 4.7 1.6 8.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) UPF0197 PF05251.7 KII85180.1 - 1.9 8.8 5.1 3.7 7.9 2.4 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0197) p450 PF00067.17 KII85181.1 - 7.3e-74 248.9 0.0 8.6e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.14 KII85182.1 - 2.1e-52 178.4 0.0 3.3e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain TFIIF_alpha PF05793.7 KII85183.1 - 0.02 13.2 21.3 0.024 13.0 14.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KII85183.1 - 0.085 10.7 28.4 0.095 10.6 19.7 1.0 1 0 0 1 1 1 0 Nop14-like family Ebola_NP PF05505.7 KII85183.1 - 0.38 8.7 11.9 0.47 8.4 8.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Daxx PF03344.10 KII85183.1 - 6 5.2 22.5 7.4 4.9 15.6 1.1 1 0 0 1 1 1 0 Daxx Family P_proprotein PF01483.15 KII85184.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Proprotein convertase P-domain Asp PF00026.18 KII85185.1 - 2.3e-52 178.2 17.2 5.5e-52 176.9 11.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII85185.1 - 0.00029 20.8 9.3 0.0006 19.7 3.3 3.3 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII85185.1 - 0.0038 17.6 5.9 0.37 11.3 1.5 2.9 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KII85185.1 - 0.028 13.9 0.4 0.46 10.0 0.2 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal HTH_33 PF13592.1 KII85187.1 - 0.035 13.6 0.1 0.084 12.4 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Gemini_AL1 PF00799.15 KII85187.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Geminivirus Rep catalytic domain LMSTEN PF07988.7 KII85187.1 - 1.2 8.5 4.5 1 8.7 0.9 2.1 2 0 0 2 2 2 0 LMSTEN motif GSHPx PF00255.14 KII85189.1 - 1.8e-39 133.4 0.1 2.2e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KII85189.1 - 3.6e-07 29.9 0.0 9.6e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII85189.1 - 9.4e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 KII85189.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) SCO1-SenC PF02630.9 KII85189.1 - 0.068 12.7 0.0 1.4 8.4 0.0 2.2 2 1 0 2 2 2 0 SCO1/SenC NAD_binding_10 PF13460.1 KII85190.1 - 0.014 15.4 1.0 0.64 10.0 0.3 2.6 2 1 0 2 2 2 0 NADH(P)-binding FHA PF00498.21 KII85190.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 FHA domain NmrA PF05368.8 KII85190.1 - 0.16 11.2 0.1 0.31 10.2 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family Herpes_DNAp_acc PF04929.7 KII85190.1 - 2.3 7.0 4.0 3.2 6.6 2.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor F-box-like PF12937.2 KII85191.1 - 4.7e-07 29.4 0.5 4.7e-07 29.4 0.3 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KII85191.1 - 0.038 13.6 0.0 0.25 11.0 0.0 2.5 2 1 0 2 2 2 0 F-box domain Vps51 PF08700.6 KII85192.1 - 3.4e-25 87.6 0.5 4.6e-25 87.2 0.4 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KII85192.1 - 0.0011 18.9 0.8 0.0017 18.3 0.6 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 KII85192.1 - 0.0043 15.5 1.5 0.0053 15.2 1.1 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.7 KII85192.1 - 0.024 14.8 1.3 0.036 14.3 0.9 1.2 1 0 0 1 1 1 0 FlgN protein DUF3086 PF11285.3 KII85192.1 - 0.11 11.2 0.3 0.13 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF427 PF04248.7 KII85194.1 - 1.2e-36 124.2 0.0 2.3e-29 100.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF1080 PF06439.6 KII85194.1 - 0.029 14.2 0.0 10 5.9 0.0 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1080) GTP_EFTU PF00009.22 KII85195.1 - 2.7e-64 216.0 0.1 4e-64 215.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KII85195.1 - 8.5e-39 131.8 0.0 2.1e-38 130.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KII85195.1 - 2e-21 75.6 0.0 4.6e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KII85195.1 - 4.7e-13 48.7 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KII85195.1 - 2.4e-07 30.7 0.0 1e-06 28.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII85195.1 - 3.4e-05 23.7 0.2 6.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KII85195.1 - 0.064 12.7 0.8 0.21 11.0 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gti1_Pac2 PF09729.4 KII85195.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.6 2 0 0 2 2 2 0 Gti1/Pac2 family BTB PF00651.26 KII85196.1 - 0.0024 17.8 0.1 0.0047 16.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.17 KII85199.1 - 8.2e-72 242.1 0.0 1e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 KII85202.1 - 0.00071 19.5 0.1 0.0069 16.3 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain Mito_fiss_reg PF05308.6 KII85203.1 - 0.097 12.0 2.5 0.11 11.9 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator BTB PF00651.26 KII85204.1 - 1.5e-05 24.9 0.1 0.005 16.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain F-box-like PF12937.2 KII85207.1 - 0.0017 18.0 0.1 0.0049 16.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII85207.1 - 0.095 12.3 0.2 51 3.6 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 KII85208.1 - 0.0015 18.0 0.3 0.75 9.4 0.0 4.4 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) Metallophos PF00149.23 KII85209.1 - 2.9e-06 26.8 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 KII85209.1 - 0.037 12.0 0.1 0.083 10.9 0.0 1.5 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase eIF-5_eIF-2B PF01873.12 KII85210.1 - 1.2e-40 138.0 0.0 2.3e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KII85210.1 - 1.2e-26 92.4 0.4 3.3e-26 91.0 0.1 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Whi5 PF08528.6 KII85211.1 - 1.2e-05 24.7 1.4 3e-05 23.4 0.9 1.7 1 0 0 1 1 1 1 Whi5 like Pkinase PF00069.20 KII85212.1 - 1.3e-45 155.6 0.0 8.8e-26 90.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII85212.1 - 2.7e-20 72.5 0.0 2e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII85212.1 - 2.3e-08 33.3 0.0 8.8e-06 24.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Ribosomal_60s PF00428.14 KII85212.1 - 0.00026 21.3 0.3 0.00026 21.3 0.2 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein APH PF01636.18 KII85212.1 - 0.00092 19.0 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4654 PF15547.1 KII85212.1 - 0.2 11.9 0.6 0.44 10.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) HTH_21 PF13276.1 KII85215.1 - 0.0034 17.3 0.4 1 9.4 0.0 2.1 2 0 0 2 2 2 2 HTH-like domain BTB PF00651.26 KII85216.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_4 PF08386.5 KII85217.1 - 2.7e-18 65.7 0.0 6.6e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KII85217.1 - 7.3e-15 55.1 0.0 1e-13 51.4 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII85217.1 - 8.2e-15 55.2 0.0 4.5e-14 52.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII85217.1 - 0.00011 21.9 0.0 0.0021 17.8 0.0 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KII85218.1 - 9e-22 76.9 0.1 1.9e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KII85218.1 - 8e-13 48.4 0.1 1.1e-11 44.7 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII85218.1 - 4.1e-11 43.1 0.2 2.4e-10 40.6 0.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII85218.1 - 0.00018 21.2 0.0 0.0068 16.1 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KII85218.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase p450 PF00067.17 KII85219.1 - 5e-65 219.8 0.0 6.4e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_2 PF07719.12 KII85220.1 - 3e-11 42.3 8.0 0.00031 20.4 0.9 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KII85220.1 - 4.9e-09 35.6 9.6 2.9e-06 26.8 4.5 2.6 2 1 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 KII85220.1 - 8.6e-09 35.2 0.3 0.0052 17.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII85220.1 - 5.2e-08 33.3 3.8 8.1e-07 29.5 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII85220.1 - 6.2e-08 32.8 2.8 8.9e-08 32.3 0.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII85220.1 - 7.9e-06 25.9 2.6 0.0086 16.4 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KII85220.1 - 2.4e-05 24.3 2.0 4.9e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KII85220.1 - 2.7e-05 23.6 8.0 0.035 13.8 0.0 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII85220.1 - 8.4e-05 22.0 9.0 0.01 15.3 1.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII85220.1 - 0.00032 20.5 5.7 0.00068 19.5 1.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KII85220.1 - 0.00039 20.4 4.7 0.075 13.2 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KII85220.1 - 0.00077 18.3 2.1 0.00077 18.3 1.4 1.7 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 KII85220.1 - 0.00096 18.7 0.7 2.1 8.3 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 KII85220.1 - 0.0081 16.3 0.1 12 6.4 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR PF01535.15 KII85220.1 - 0.0089 15.9 0.4 1.4 9.0 0.0 3.0 3 0 0 3 3 3 1 PPR repeat Fis1_TPR_C PF14853.1 KII85220.1 - 0.049 13.5 4.0 0.22 11.4 0.5 2.7 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Nucleopor_Nup85 PF07575.8 KII85220.1 - 0.079 11.1 0.1 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Alkyl_sulf_dimr PF14863.1 KII85220.1 - 0.2 11.8 4.4 0.2 11.8 0.8 2.4 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation MIT PF04212.13 KII85220.1 - 0.2 11.5 4.0 4.2 7.3 0.0 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ribosomal_S13 PF00416.17 KII85220.1 - 0.27 11.7 1.4 0.49 10.8 1.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S13/S18 TPR_20 PF14561.1 KII85220.1 - 2 8.5 6.0 1.4 9.0 0.5 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat PAPA-1 PF04795.7 KII85221.1 - 0.15 12.7 3.9 0.21 12.3 2.7 1.1 1 0 0 1 1 1 0 PAPA-1-like conserved region Pkinase PF00069.20 KII85222.1 - 0.00019 20.6 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII85222.1 - 0.0084 15.8 0.2 0.048 13.3 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII85222.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family zf-CCCH PF00642.19 KII85224.1 - 5.5e-08 32.3 6.6 1.8e-05 24.2 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII85224.1 - 0.0049 16.8 12.8 0.007 16.3 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type TPR_11 PF13414.1 KII85226.1 - 8.9e-17 60.5 1.8 1e-09 37.8 0.2 2.4 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 KII85226.1 - 1.5e-09 38.3 0.0 8.4e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.1 KII85226.1 - 3.5e-05 24.3 4.6 0.037 14.7 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII85226.1 - 0.0031 17.3 5.3 0.4 10.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII85226.1 - 0.014 15.9 0.2 0.014 15.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII85226.1 - 0.016 15.4 0.4 0.45 10.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII85226.1 - 0.019 14.5 0.1 0.62 9.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KII85226.1 - 0.084 12.7 2.5 1.4 8.7 0.5 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF4110 PF13422.1 KII85227.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Ribosomal_L10 PF00466.15 KII85228.1 - 1.2e-26 92.5 0.9 2.2e-26 91.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KII85228.1 - 1.3e-22 79.9 11.3 7.6e-22 77.5 5.5 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein AF1Q PF15017.1 KII85228.1 - 0.12 12.2 1.9 0.22 11.4 1.3 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Glyco_transf_20 PF00982.16 KII85229.1 - 8.9e-185 614.6 0.0 3.9e-184 612.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KII85229.1 - 0.093 12.1 0.2 9.9 5.5 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 S10_plectin PF03501.10 KII85230.1 - 2.3e-43 145.9 0.2 2.7e-43 145.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 KII85230.1 - 0.0024 17.5 0.0 0.0037 16.9 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF1658 PF07871.6 KII85230.1 - 0.029 13.9 0.7 0.093 12.3 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) RRN3 PF05327.6 KII85231.1 - 0.41 8.7 11.4 0.63 8.0 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 KII85231.1 - 2 6.2 21.7 3 5.6 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KII85231.1 - 3.2 5.6 12.3 5.5 4.8 8.5 1.3 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 KII85233.1 - 6.4e-17 60.7 11.1 0.0015 18.3 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat RIO1 PF01163.17 KII85235.1 - 0.0022 17.3 0.1 0.0039 16.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KII85235.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C3HC PF07967.8 KII85236.1 - 1.3e-24 86.4 0.0 7.1e-23 80.8 0.0 2.3 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.5 KII85236.1 - 5.5e-14 51.7 0.6 7.9e-09 35.2 0.0 3.4 3 1 0 3 3 3 2 Rsm1-like DM PF00751.13 KII85236.1 - 0.064 12.8 0.2 5.9 6.4 0.0 2.5 2 0 0 2 2 2 0 DM DNA binding domain DUF2370 PF10176.4 KII85239.1 - 1.6e-63 214.1 0.0 2.8e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2668 PF10873.3 KII85239.1 - 1.8 8.7 3.8 5.2 7.2 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Nup_retrotrp_bd PF10599.4 KII85239.1 - 4.9 7.8 8.0 35 5.0 0.1 2.6 2 1 0 2 2 2 0 Retro-transposon transporting motif O-FucT PF10250.4 KII85240.1 - 3.5e-06 26.3 0.0 0.14 11.2 0.0 3.0 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase zf-MYND PF01753.13 KII85242.1 - 7.1e-11 41.7 10.7 1.7e-10 40.5 7.4 1.7 1 0 0 1 1 1 1 MYND finger BAH PF01426.13 KII85243.1 - 2.1e-14 53.2 0.0 6.6e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 BAH domain AAA PF00004.24 KII85243.1 - 3.7e-13 49.8 0.0 7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII85243.1 - 2.2e-09 37.5 0.4 2.6e-08 34.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII85243.1 - 8e-07 29.2 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII85243.1 - 0.00011 21.8 0.3 0.00091 18.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KII85243.1 - 0.0012 17.9 0.0 0.0031 16.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KII85243.1 - 0.0066 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KII85243.1 - 0.0084 15.8 0.1 0.12 12.1 0.1 2.4 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KII85243.1 - 0.027 14.1 0.0 0.13 11.9 0.0 2.1 1 1 0 1 1 1 0 NACHT domain TIP49 PF06068.8 KII85243.1 - 0.071 11.8 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus PIF1 PF05970.9 KII85243.1 - 0.11 11.4 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase YL1 PF05764.8 KII85243.1 - 0.97 8.9 20.0 1 8.9 12.9 1.8 1 1 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 KII85243.1 - 1.4 6.6 13.8 2.1 6.1 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family Aldose_epim PF01263.15 KII85244.1 - 9.5e-26 90.5 0.0 2.4e-11 43.3 0.0 3.2 1 1 1 2 2 2 2 Aldose 1-epimerase Fungal_trans PF04082.13 KII85245.1 - 3.2e-32 111.4 0.1 5.4e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85245.1 - 0.00021 21.1 5.0 0.0004 20.2 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KII85245.1 - 0.086 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Cytochrom_C PF00034.16 KII85246.1 - 1.7e-08 35.1 0.2 3.5e-08 34.1 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KII85246.1 - 7.1e-08 32.4 3.2 1.2e-06 28.6 2.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KII85246.1 - 6.1e-05 22.4 0.2 0.00057 19.3 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 KII85246.1 - 0.13 11.9 0.1 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain GFO_IDH_MocA PF01408.17 KII85247.1 - 1.8e-16 60.7 0.1 5.2e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII85247.1 - 0.0044 16.8 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 KII85247.1 - 0.027 14.9 0.1 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DSPc PF00782.15 KII85249.1 - 7.8e-24 83.7 0.0 8.3e-21 73.9 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain ANTAR PF03861.9 KII85249.1 - 0.0078 15.7 0.1 5.5 6.6 0.0 3.2 3 0 0 3 3 3 2 ANTAR domain Y_phosphatase PF00102.22 KII85249.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ABC2_membrane PF01061.19 KII85250.1 - 6e-33 113.7 20.6 6e-33 113.7 14.3 1.7 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 KII85250.1 - 5.9e-28 97.8 0.0 9.4e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KII85250.1 - 2.7e-09 37.3 0.1 1.8e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII85250.1 - 0.00044 19.7 0.0 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KII85250.1 - 0.00062 18.9 25.1 0.00062 18.9 17.4 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 KII85250.1 - 0.001 18.5 0.2 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KII85250.1 - 0.0017 17.5 0.1 0.0036 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 EGF_2 PF07974.8 KII85250.1 - 0.0029 17.7 9.5 0.0029 17.7 6.6 3.8 3 0 0 3 3 3 2 EGF-like domain SMC_N PF02463.14 KII85250.1 - 0.003 16.8 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain hEGF PF12661.2 KII85250.1 - 0.0083 16.1 2.5 0.0083 16.1 1.7 4.2 4 0 0 4 4 3 2 Human growth factor-like EGF MMR_HSR1 PF01926.18 KII85250.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KII85250.1 - 0.017 15.2 0.1 0.053 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KII85250.1 - 0.023 13.7 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KII85250.1 - 0.028 14.1 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KII85250.1 - 0.028 15.2 0.0 0.055 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KII85250.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 KII85250.1 - 0.029 13.0 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 KII85250.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII85250.1 - 0.047 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 KII85250.1 - 0.13 11.7 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 KII85250.1 - 0.24 10.1 0.3 0.39 9.4 0.2 1.2 1 0 0 1 1 1 0 ArgK protein CXCL17 PF15211.1 KII85250.1 - 0.3 11.4 5.6 0.083 13.2 0.8 2.2 2 0 0 2 2 2 0 VEGF co-regulated chemokine 1 AAA_23 PF13476.1 KII85250.1 - 0.35 11.1 0.5 0.6 10.3 0.4 1.3 1 0 0 1 1 1 0 AAA domain DUF1180 PF06679.7 KII85250.1 - 0.48 10.3 1.9 1 9.2 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ninjurin PF04923.7 KII85251.1 - 5.7 6.7 8.2 28 4.4 5.6 2.4 1 1 0 1 1 1 0 Ninjurin DUF2919 PF11143.3 KII85251.1 - 6 6.6 11.1 0.5 10.1 0.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2919) PgpA PF04608.8 KII85251.1 - 7.1 6.4 13.8 6.6 6.5 3.9 2.5 2 1 0 2 2 2 0 Phosphatidylglycerophosphatase A GalKase_gal_bdg PF10509.4 KII85252.1 - 2.6e-19 68.2 0.1 5.1e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KII85252.1 - 1.6e-12 47.2 1.5 1.6e-12 47.2 1.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KII85252.1 - 4e-10 39.7 0.1 1.3e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal NmrA PF05368.8 KII85253.1 - 1.5e-49 168.3 0.0 1.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII85253.1 - 1.6e-13 51.0 0.0 2.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII85253.1 - 3.5e-05 23.7 0.3 6e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII85253.1 - 0.00016 21.4 0.1 0.00027 20.6 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KII85253.1 - 0.00037 19.2 0.0 0.00058 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII85253.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Nitro_FeMo-Co PF02579.12 KII85253.1 - 0.058 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Col_cuticle_N PF01484.12 KII85255.1 - 0.17 11.5 0.3 0.17 11.5 0.2 1.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain zf-C2H2 PF00096.21 KII85256.1 - 0.025 14.8 1.8 0.025 14.8 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII85256.1 - 0.05 13.9 0.5 0.05 13.9 0.3 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger HSP20 PF00011.16 KII85257.1 - 3.6e-05 23.5 0.0 5.3e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family DUF1482 PF07358.6 KII85257.1 - 0.095 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) Aminotran_MocR PF12897.2 KII85258.1 - 0.031 12.8 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Dickkopf_N PF04706.7 KII85258.1 - 1.9 8.7 27.4 0.88 9.7 5.7 4.1 3 1 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region PPI_Ypi1 PF07491.6 KII85259.1 - 6.8e-25 86.4 0.9 1.7e-24 85.2 0.6 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 KII85259.1 - 0.18 10.1 7.5 0.19 10.0 5.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 KII85259.1 - 0.49 8.3 4.3 0.5 8.3 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3295 PF11702.3 KII85260.1 - 5.3e-14 52.1 25.8 1.1e-13 51.0 0.4 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KII85260.1 - 1.3e-11 43.8 2.0 2.8e-11 42.7 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CDC45 PF02724.9 KII85260.1 - 3.5 5.5 6.2 7.5 4.4 4.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KII85260.1 - 3.9 7.0 9.0 5.3 6.6 4.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RR_TM4-6 PF06459.7 KII85260.1 - 4.1 7.2 6.2 11 5.7 4.3 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IDO PF01231.13 KII85262.1 - 6.6e-110 367.4 0.0 9.3e-110 366.9 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TFIIF_beta PF02270.10 KII85264.1 - 3.3e-49 168.1 0.0 2.1e-48 165.4 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 KII85264.1 - 0.066 13.2 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 IS66 C-terminal element HAD_2 PF13419.1 KII85267.1 - 4.8e-21 75.7 0.0 1.1e-20 74.5 0.0 1.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KII85267.1 - 7.3e-07 29.0 0.0 1.4e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII85267.1 - 0.00061 20.2 0.0 0.002 18.5 0.0 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII85267.1 - 0.0045 17.1 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KII85267.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-DHHC PF01529.15 KII85268.1 - 4.6e-33 114.0 1.7 4.6e-33 114.0 1.2 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase MIS13 PF08202.6 KII85269.1 - 4.7e-28 98.1 0.9 4.7e-28 98.1 0.6 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Pkinase PF00069.20 KII85271.1 - 2.3e-05 23.6 0.1 9.5e-05 21.6 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KII85271.1 - 2.7e-05 23.6 0.0 7.1e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KII85271.1 - 4.1e-05 23.4 0.0 6.3e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII85271.1 - 0.0015 18.1 0.1 0.0025 17.4 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KII85271.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII85272.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII85272.1 - 0.0009 18.6 1.7 0.0013 18.0 0.0 2.0 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.20 KII85272.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Kdo PF06293.9 KII85272.1 - 0.029 13.4 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2019 PF09450.5 KII85272.1 - 0.15 11.9 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) THP2 PF09432.5 KII85272.1 - 0.15 11.9 0.8 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Tho complex subunit THP2 DPBB_1 PF03330.13 KII85274.1 - 0.00066 19.6 0.2 0.0009 19.1 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel gag-asp_proteas PF13975.1 KII85274.1 - 0.0015 18.3 0.2 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Exo_endo_phos PF03372.18 KII85275.1 - 0.00038 20.4 0.2 0.00056 19.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KII85275.1 - 0.0018 17.8 0.1 0.14 11.7 0.0 2.4 2 1 0 2 2 2 2 Endonuclease-reverse transcriptase Ribosomal_60s PF00428.14 KII85276.1 - 0.42 11.0 4.9 0.54 10.7 3.4 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 KII85276.1 - 0.76 9.2 6.3 0.79 9.2 4.3 1.1 1 0 0 1 1 1 0 Nucleoplasmin AAA_13 PF13166.1 KII85277.1 - 0.7 8.2 11.9 0.96 7.8 8.2 1.1 1 0 0 1 1 1 0 AAA domain NYD-SP28 PF14772.1 KII85277.1 - 0.88 9.7 10.2 0.16 12.0 1.8 3.1 2 1 1 3 3 3 0 Sperm tail DUF1470 PF07336.6 KII85277.1 - 1.9 8.8 8.8 0.23 11.7 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1470) FlxA PF14282.1 KII85277.1 - 2.8 7.9 7.2 2.7 7.9 0.3 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.1 KII85277.1 - 4.2 6.2 9.9 8.8 5.1 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NYD-SP28_assoc PF14775.1 KII85278.1 - 0.022 14.4 3.5 0.36 10.5 0.1 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain RNA_pol_Rpb2_45 PF10385.4 KII85278.1 - 0.058 13.2 0.8 0.2 11.5 0.2 2.1 2 1 0 2 2 2 0 RNA polymerase beta subunit external 1 domain DUF745 PF05335.8 KII85278.1 - 0.16 11.5 16.6 0.057 12.9 7.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) CcdA PF07362.7 KII85278.1 - 0.21 11.4 4.4 0.57 10.0 3.1 1.8 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA DUF3584 PF12128.3 KII85278.1 - 0.94 6.7 21.5 1.1 6.4 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KII85278.1 - 0.94 7.8 12.4 1.2 7.5 8.6 1.1 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.8 KII85278.1 - 1.3 9.4 15.9 4.5 7.7 0.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 KII85278.1 - 1.8 8.6 22.3 2.4 8.2 8.8 2.8 1 1 1 3 3 3 0 DivIVA protein Exonuc_VII_S PF02609.11 KII85278.1 - 2.2 8.1 0.0 2.2 8.1 0.0 3.4 4 0 0 4 4 4 0 Exonuclease VII small subunit DUF3450 PF11932.3 KII85278.1 - 2.8 7.1 18.6 2 7.6 1.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.1 KII85278.1 - 2.9 6.7 16.8 13 4.5 11.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sulfatase_C PF14707.1 KII85278.1 - 4.6 7.5 5.5 3.5 7.9 0.9 2.3 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase Prefoldin_2 PF01920.15 KII85278.1 - 5 6.9 15.4 86 2.9 6.6 3.9 3 1 0 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 KII85278.1 - 5.5 6.6 20.6 75 2.9 8.1 2.8 1 1 1 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 KII85278.1 - 6.7 6.4 23.0 5.3e+02 0.3 16.0 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GST_N_3 PF13417.1 KII85279.1 - 4.6e-18 65.2 0.0 7.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII85279.1 - 1.4e-15 57.0 0.0 1.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII85279.1 - 4.2e-15 55.6 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII85279.1 - 2.4e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII85279.1 - 2.2e-09 37.0 0.4 3.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII85279.1 - 0.0003 21.2 0.1 0.00045 20.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 KII85280.1 - 2.2e-06 27.2 0.0 0.0084 15.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII85280.1 - 2.7e-06 26.8 0.1 4.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII85280.1 - 4e-05 23.7 1.2 6.1e-05 23.1 0.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII85280.1 - 0.00086 18.3 0.2 0.0015 17.4 0.2 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KII85280.1 - 0.012 15.9 0.1 0.042 14.1 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KII85280.1 - 0.044 12.4 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KII85280.1 - 0.091 13.2 0.2 0.22 11.9 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KII85280.1 - 0.097 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lon_C PF05362.8 KII85281.1 - 1e-67 227.4 0.2 1.9e-67 226.5 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KII85281.1 - 2.1e-37 128.7 0.9 7.9e-37 126.9 0.1 2.2 2 1 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KII85281.1 - 2e-22 79.7 0.0 6.5e-22 78.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII85281.1 - 2.5e-08 33.7 0.0 4.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KII85281.1 - 1.2e-06 28.0 0.0 2.5e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.6 KII85281.1 - 1.5e-05 23.8 0.0 3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.9 KII85281.1 - 1.5e-05 24.9 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KII85281.1 - 3.8e-05 24.5 0.0 0.00015 22.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII85281.1 - 3.8e-05 23.7 0.1 0.00037 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII85281.1 - 0.0002 21.4 0.0 0.0026 17.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII85281.1 - 0.00031 19.8 0.0 0.0016 17.5 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KII85281.1 - 0.0009 19.1 0.0 0.0027 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII85281.1 - 0.0028 17.9 2.5 0.0044 17.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KII85281.1 - 0.015 15.0 1.1 4.2 6.9 0.0 3.2 2 2 0 3 3 3 0 Archaeal ATPase ATP-synt_ab PF00006.20 KII85281.1 - 0.015 14.7 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 KII85281.1 - 0.017 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.8 KII85281.1 - 0.025 13.3 0.1 0.17 10.5 0.0 2.3 3 0 0 3 3 3 0 TIP49 C-terminus IstB_IS21 PF01695.12 KII85281.1 - 0.025 14.0 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KII85281.1 - 0.028 14.5 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KII85281.1 - 0.045 12.9 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KII85281.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KII85281.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KII85281.1 - 0.063 12.9 0.1 0.33 10.6 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_21 PF13304.1 KII85281.1 - 0.07 13.0 0.4 1 9.2 0.0 2.5 2 1 1 3 3 3 0 AAA domain UPF0079 PF02367.12 KII85281.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KII85281.1 - 0.11 12.8 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 ABC transporter PrpF PF04303.8 KII85286.1 - 3.8e-78 262.8 0.2 4.7e-78 262.5 0.1 1.0 1 0 0 1 1 1 1 PrpF protein FeoA PF04023.9 KII85288.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FeoA domain GFA PF04828.9 KII85289.1 - 1e-26 92.6 0.1 1.6e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KII85289.1 - 0.1 11.8 4.3 0.24 10.6 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27 PF01599.14 KII85289.1 - 0.15 11.8 2.0 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S27a Zn_ribbon_recom PF13408.1 KII85289.1 - 0.54 10.5 0.0 0.54 10.5 0.0 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 KII85289.1 - 2.8 7.5 6.7 1.2 8.6 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rootletin PF15035.1 KII85291.1 - 0.056 13.4 1.8 3.1 7.7 0.2 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CDC27 PF09507.5 KII85292.1 - 3.1e-46 158.5 59.2 9.8e-46 156.8 41.0 1.7 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 PS_Dcarbxylase PF02666.10 KII85293.1 - 2.8e-53 180.2 0.0 4.7e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KII85293.1 - 2.8e-34 116.8 0.1 5.8e-16 58.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KII85293.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain GMP_synt_C PF00958.17 KII85294.1 - 4.2e-41 138.5 0.1 9.9e-41 137.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 KII85294.1 - 3.1e-30 105.0 0.0 5.5e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KII85294.1 - 9.8e-11 41.4 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 KII85294.1 - 6.5e-10 38.3 0.2 3.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 KII85294.1 - 0.003 16.1 0.1 0.0052 15.4 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 KII85294.1 - 0.0046 16.4 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 KII85294.1 - 0.0066 15.7 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KII85294.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Arginosuc_synth PF00764.14 KII85294.1 - 0.06 12.3 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 KII85294.1 - 0.093 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 PP-loop family DUF2392 PF10288.4 KII85294.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) DUF3037 PF11236.3 KII85295.1 - 0.084 12.9 2.1 0.17 11.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DASH_Spc34 PF08657.5 KII85295.1 - 0.4 10.2 9.3 1.2 8.7 2.8 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 Atg14 PF10186.4 KII85295.1 - 1.8 7.4 11.5 3.2 6.6 8.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KII85295.1 - 4.9 6.7 12.7 8.7 5.8 8.8 1.4 1 0 0 1 1 1 0 IncA protein RhaT PF06379.7 KII85297.1 - 0.00096 18.2 0.1 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 L-rhamnose-proton symport protein (RhaT) UPF0257 PF06788.8 KII85298.1 - 0.059 12.6 0.0 0.062 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) Tad PF13400.1 KII85298.1 - 0.068 13.2 0.3 0.068 13.2 0.2 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like RhaT PF06379.7 KII85301.1 - 0.00088 18.3 0.9 0.00096 18.2 0.2 1.4 1 1 0 1 1 1 1 L-rhamnose-proton symport protein (RhaT) YuiB PF14068.1 KII85301.1 - 0.26 11.6 9.1 2.3 8.5 1.1 2.2 1 1 1 2 2 2 0 Putative membrane protein AtpR PF12966.2 KII85301.1 - 1.5 9.0 8.0 2 8.5 4.0 2.4 1 1 1 2 2 2 0 N-ATPase, AtpR subunit MFS_1 PF07690.11 KII85303.1 - 1.9e-17 63.0 38.2 2.8e-17 62.4 25.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.2 KII85304.1 - 1.2e-07 31.2 1.5 3.3e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 F-box-like SecD_SecF PF02355.11 KII85308.1 - 0.072 12.2 6.0 0.12 11.6 4.2 1.3 1 0 0 1 1 1 0 Protein export membrane protein Rota_NS26 PF01525.11 KII85311.1 - 0.011 15.4 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Rotavirus NS26 C6 PF01681.12 KII85311.1 - 0.12 12.4 2.9 0.14 12.2 0.4 2.2 1 1 1 2 2 2 0 C6 domain GATA PF00320.22 KII85313.1 - 0.11 11.8 4.9 2.2 7.6 0.3 2.5 2 0 0 2 2 2 0 GATA zinc finger YABBY PF04690.8 KII85316.1 - 1.3e-07 31.9 0.8 1.3e-07 31.9 0.5 1.4 2 0 0 2 2 2 1 YABBY protein HMG_box PF00505.14 KII85316.1 - 8.1e-07 29.2 0.7 8.1e-07 29.2 0.5 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box DUF1014 PF06244.7 KII85316.1 - 0.003 17.7 1.0 0.003 17.7 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box_2 PF09011.5 KII85316.1 - 0.0054 17.0 10.0 0.043 14.1 7.0 2.3 1 1 0 1 1 1 1 HMG-box domain DUF4449 PF14613.1 KII85317.1 - 1.3e-16 60.9 0.0 1.4e-15 57.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) SPO22 PF08631.5 KII85317.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF3357 PF11837.3 KII85318.1 - 0.085 12.7 0.0 0.085 12.7 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) PBP1_TM PF14812.1 KII85318.1 - 0.098 12.9 0.5 0.098 12.9 0.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATG27 PF09451.5 KII85318.1 - 0.18 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 CDC45 PF02724.9 KII85318.1 - 0.34 8.9 0.6 0.48 8.3 0.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 KII85318.1 - 0.51 9.8 3.9 0.74 9.3 2.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin CHAD PF05235.9 KII85320.1 - 0.073 12.6 1.9 0.18 11.3 1.2 1.7 1 1 0 1 1 1 0 CHAD domain CZB PF13682.1 KII85320.1 - 0.084 13.0 0.4 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Dimer_Tnp_hAT PF05699.9 KII85324.1 - 1.7e-05 24.3 0.1 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region S4 PF01479.20 KII85325.1 - 4.5e-10 38.8 0.0 8.1e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KII85325.1 - 0.00019 20.9 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 S4 domain DUF3317 PF11779.3 KII85326.1 - 2.1e-10 39.8 3.2 3.1e-10 39.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Epiglycanin_C PF14654.1 KII85326.1 - 0.059 13.3 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Ferric_reduct PF01794.14 KII85327.1 - 6.5e-14 52.1 8.6 1.7e-13 50.7 5.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KII85327.1 - 1.2e-13 50.7 0.0 3.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KII85327.1 - 1.8e-08 34.4 0.0 1.6e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain CUE PF02845.11 KII85328.1 - 4.5e-12 45.2 0.0 6.6e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain SNARE PF05739.14 KII85330.1 - 1.4e-10 40.7 0.9 1.4e-10 40.7 0.6 2.7 2 1 1 3 3 3 2 SNARE domain KxDL PF10241.4 KII85330.1 - 0.018 14.9 0.4 0.043 13.7 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Fusion_gly PF00523.13 KII85330.1 - 0.049 11.6 0.2 0.07 11.1 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Tropomyosin PF00261.15 KII85330.1 - 0.21 10.6 1.0 0.31 10.0 0.2 1.6 2 0 0 2 2 2 0 Tropomyosin Lge1 PF11488.3 KII85330.1 - 0.52 10.5 3.5 10 6.4 0.3 3.2 2 2 0 2 2 2 0 Transcriptional regulatory protein LGE1 EzrA PF06160.7 KII85330.1 - 0.81 7.7 4.3 0.25 9.4 0.0 2.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA SOUL PF04832.7 KII85331.1 - 0.0052 16.3 0.3 0.01 15.3 0.2 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein EPSP_synthase PF00275.15 KII85332.1 - 5.9e-115 384.0 0.0 9.4e-115 383.3 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KII85332.1 - 1.5e-98 328.8 0.0 3.7e-98 327.6 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KII85332.1 - 3e-60 203.6 0.0 4.9e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KII85332.1 - 2.6e-34 118.3 0.0 9.1e-33 113.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KII85332.1 - 9.9e-25 86.4 0.0 2.5e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KII85332.1 - 3.3e-13 49.9 0.0 8.7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KII85332.1 - 9e-09 35.0 0.0 2.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KII85332.1 - 0.00039 21.2 0.0 0.00098 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII85332.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 KII85333.1 - 1.8e-24 86.7 0.0 3.8e-24 85.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII85333.1 - 4e-13 49.5 0.1 1.7e-11 44.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII85333.1 - 1.9e-06 28.0 0.1 0.0094 16.0 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KII85333.1 - 0.0014 18.8 0.0 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF793 PF05633.6 KII85333.1 - 0.064 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) rpo132 PF12415.3 KII85334.1 - 0.13 11.2 0.3 0.25 10.3 0.2 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase LRR_2 PF07723.8 KII85334.1 - 7.6 7.2 6.9 11 6.7 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat Rib_5-P_isom_A PF06026.9 KII85335.1 - 8.7e-56 187.9 0.0 1.1e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Semialdhyde_dh PF01118.19 KII85335.1 - 0.035 14.3 0.0 0.085 13.1 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_5 PF12695.2 KII85336.1 - 3.1e-23 82.1 0.0 5.1e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII85336.1 - 2.1e-18 67.0 0.1 7.8e-17 61.9 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KII85336.1 - 3.6e-06 26.8 0.0 6.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KII85336.1 - 5.5e-06 25.9 0.0 0.061 12.7 0.0 3.0 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KII85336.1 - 7.4e-06 25.6 0.0 0.0011 18.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 KII85336.1 - 0.00012 20.6 0.3 0.0069 14.9 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 KII85336.1 - 0.0013 18.0 0.0 0.063 12.5 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KII85336.1 - 0.0018 17.9 0.1 0.0051 16.4 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII85336.1 - 0.0054 15.9 0.0 0.026 13.7 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.7 KII85336.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.7 KII85336.1 - 0.068 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 KII85336.1 - 0.075 12.6 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.8 KII85336.1 - 0.085 12.2 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) MSP1b PF03429.8 KII85337.1 - 0.027 12.3 0.4 0.034 12.0 0.3 1.2 1 0 0 1 1 1 0 Major surface protein 1B DUF760 PF05542.6 KII85337.1 - 0.13 12.4 0.0 0.6 10.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF760) Spc97_Spc98 PF04130.8 KII85338.1 - 3.4e-122 408.5 0.0 4.2e-122 408.2 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Snapin_Pallidin PF14712.1 KII85338.1 - 0.098 12.9 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin WD40 PF00400.27 KII85343.1 - 8.4e-07 28.6 7.0 0.22 11.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Tbf5 PF06331.7 KII85344.1 - 1.2e-20 73.0 0.4 1.3e-20 72.9 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CBM_20 PF00686.14 KII85346.1 - 2.3e-53 177.7 8.3 1.7e-27 94.8 0.2 3.0 3 0 0 3 3 3 2 Starch binding domain Alpha-amylase PF00128.19 KII85346.1 - 1.3e-17 64.2 2.2 3.1e-17 62.9 0.1 2.3 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KII85346.1 - 1.6e-08 34.5 0.0 6.4e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Imm33 PF15580.1 KII85346.1 - 0.1 12.0 0.2 0.8 9.2 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 33 F-box-like PF12937.2 KII85351.1 - 1.8e-07 30.7 0.8 3.3e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 KII85352.1 - 4.9e-109 352.7 54.2 1.6e-14 53.0 0.2 9.9 9 1 0 9 9 9 9 WD domain, G-beta repeat PD40 PF07676.7 KII85352.1 - 1.8e-21 75.3 17.4 0.75 9.5 0.1 10.3 10 0 0 10 10 10 9 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KII85352.1 - 1.1e-08 33.6 14.3 0.083 11.0 0.4 6.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 KII85352.1 - 1.6e-08 33.2 0.2 0.17 10.0 0.0 4.5 2 1 3 5 5 5 4 Protein of unknown function (DUF3312) DUF1258 PF06869.7 KII85352.1 - 2.7e-07 29.9 14.7 0.56 9.2 0.1 7.1 1 1 7 8 8 8 3 Protein of unknown function (DUF1258) DUF1652 PF07865.6 KII85352.1 - 1.5e-06 27.7 0.0 35 4.0 0.0 6.9 2 1 5 7 7 7 0 Protein of unknown function (DUF1652) RicinB_lectin_2 PF14200.1 KII85352.1 - 3.5e-05 24.1 2.7 1.8 9.0 0.0 4.4 1 1 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.11 KII85352.1 - 0.00017 19.9 5.0 0.2 9.9 0.1 4.1 1 1 4 5 5 5 4 Cytochrome D1 heme domain Nbas_N PF15492.1 KII85352.1 - 0.0018 17.4 5.4 4.9 6.1 0.0 5.2 1 1 5 6 6 6 2 Neuroblastoma-amplified sequence, N terminal DUF2917 PF11142.3 KII85352.1 - 0.085 12.0 5.0 55 3.0 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2917) DUF3770 PF12603.3 KII85352.1 - 0.39 9.8 1.9 43 3.1 0.0 4.1 4 2 1 5 5 5 0 Protein of unknown function (DUF3770) Proteasome_A_N PF10584.4 KII85352.1 - 7.5 5.9 22.1 2.5e+02 1.1 0.0 9.3 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature NACHT PF05729.7 KII85353.1 - 1.1e-10 41.4 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII85353.1 - 1.1e-06 28.7 0.6 1.6e-05 24.9 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KII85353.1 - 7.1e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 KII85353.1 - 0.00016 20.6 0.0 0.00032 19.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KII85353.1 - 0.00018 21.3 0.1 0.00077 19.2 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 KII85353.1 - 0.0012 19.0 0.1 0.004 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII85353.1 - 0.0016 18.5 0.0 0.0047 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KII85353.1 - 0.0043 16.9 0.1 0.042 13.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII85353.1 - 0.041 14.1 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KII85353.1 - 0.046 14.5 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Man-6-P_recep PF02157.10 KII85356.1 - 0.092 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor WD40 PF00400.27 KII85358.1 - 2.3e-87 284.0 30.3 2.1e-15 55.9 0.7 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 KII85358.1 - 6.1e-16 57.6 12.0 2.2 8.0 0.0 8.4 8 0 0 8 8 8 7 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KII85358.1 - 8.4e-10 37.4 0.0 0.032 12.4 0.0 4.2 2 2 2 4 4 4 4 Protein of unknown function (DUF3312) Nup160 PF11715.3 KII85358.1 - 1.1e-06 27.1 11.6 0.53 8.3 0.4 5.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KII85358.1 - 9.9e-06 24.0 2.3 0.04 12.2 0.1 3.5 1 1 2 3 3 3 3 Cytochrome D1 heme domain RicinB_lectin_2 PF14200.1 KII85358.1 - 3.9e-05 23.9 1.5 0.83 10.0 0.0 3.9 2 1 3 5 5 5 2 Ricin-type beta-trefoil lectin domain-like DUF1652 PF07865.6 KII85358.1 - 0.0012 18.3 0.0 5.7 6.6 0.0 5.0 5 1 1 6 6 6 1 Protein of unknown function (DUF1652) CelD_N PF02927.9 KII85358.1 - 0.0017 18.5 1.8 0.65 10.2 0.0 3.9 1 1 4 5 5 5 1 N-terminal ig-like domain of cellulase DUF374 PF04028.8 KII85358.1 - 0.0028 16.8 1.4 23 4.3 0.0 5.0 4 2 2 6 6 6 0 Domain of unknown function (DUF374) DUF1258 PF06869.7 KII85358.1 - 0.017 14.2 3.2 4.4 6.3 0.0 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF1258) PQQ_3 PF13570.1 KII85358.1 - 0.017 15.4 12.9 19 5.6 0.1 6.0 4 2 2 6 6 6 0 PQQ-like domain Nbas_N PF15492.1 KII85358.1 - 0.054 12.5 4.8 5.1 6.1 0.2 4.7 1 1 5 6 6 6 0 Neuroblastoma-amplified sequence, N terminal DUF2342 PF10103.4 KII85358.1 - 0.16 10.9 0.6 46 2.8 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2342) NACHT PF05729.7 KII85359.1 - 4.1e-11 42.8 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII85359.1 - 1.2e-06 28.6 0.5 1.4e-05 25.2 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KII85359.1 - 9.4e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 KII85359.1 - 0.00022 20.2 0.0 0.00048 19.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KII85359.1 - 0.00041 20.1 0.1 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KII85359.1 - 0.00079 19.5 0.0 0.0032 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KII85359.1 - 0.0013 18.9 0.1 0.0043 17.2 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KII85359.1 - 0.0021 17.9 0.1 0.03 14.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII85359.1 - 0.031 14.5 0.0 0.094 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KII85359.1 - 0.045 14.5 0.0 0.13 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF1193 PF06702.7 KII85359.1 - 0.088 12.2 0.2 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) AAA_30 PF13604.1 KII85359.1 - 0.16 11.5 0.3 0.62 9.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain Acetyltransf_7 PF13508.1 KII85362.1 - 7.3e-10 38.8 0.0 9.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII85362.1 - 7.5e-10 38.7 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KII85362.1 - 0.0053 16.9 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII85362.1 - 0.055 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1744 PF08490.7 KII85363.1 - 4.3e-107 358.1 0.0 6e-107 357.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KII85363.1 - 2.7e-63 213.8 0.0 4.9e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KII85363.1 - 2.2e-19 69.5 0.0 1.9e-17 63.2 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KII85363.1 - 6.6e-09 35.6 0.2 2.4e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KII85363.1 - 0.0004 20.2 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily Antig_Caf1 PF09255.5 KII85363.1 - 0.26 11.2 0.0 0.74 9.7 0.0 1.7 1 0 0 1 1 1 0 Caf1 Capsule antigen Fasciclin PF02469.17 KII85364.1 - 4.8e-08 33.0 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain Ferric_reduct PF01794.14 KII85365.1 - 1.1e-17 64.3 7.8 3.3e-17 62.7 1.6 3.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KII85365.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KII85365.1 - 9.6e-07 28.6 0.0 0.067 13.0 0.0 2.7 3 0 0 3 3 3 2 FAD-binding domain FAD_binding_3 PF01494.14 KII85366.1 - 8.6e-13 48.0 0.0 3.2e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KII85366.1 - 1.7e-06 27.1 0.2 0.00056 18.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII85366.1 - 6.2e-06 25.5 2.0 0.00026 20.2 0.5 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII85366.1 - 4.1e-05 23.5 1.2 0.00015 21.7 0.8 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII85366.1 - 5.3e-05 22.2 0.1 0.00015 20.7 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII85366.1 - 7.3e-05 22.7 0.7 0.00058 19.7 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII85366.1 - 0.00025 21.4 0.3 0.014 15.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII85366.1 - 0.0078 15.3 0.1 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KII85366.1 - 0.03 12.8 0.5 0.19 10.1 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KII85366.1 - 0.084 11.7 0.7 0.79 8.5 0.5 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Potex_coat PF06184.6 KII85366.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein GIDA PF01134.17 KII85366.1 - 0.14 11.0 0.1 0.24 10.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII85366.1 - 0.2 10.6 9.8 0.038 13.0 3.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Mo25 PF08569.6 KII85367.1 - 3.3e-124 414.2 4.6 3.7e-124 414.1 3.2 1.0 1 0 0 1 1 1 1 Mo25-like GST_N_3 PF13417.1 KII85369.1 - 2.4e-12 46.9 0.0 4.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII85369.1 - 5.7e-12 45.4 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII85369.1 - 9.5e-11 41.4 1.1 1.2e-10 41.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KII85369.1 - 2.1e-10 40.4 0.0 4.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KII85369.1 - 1.4e-09 38.0 0.1 3.1e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII85369.1 - 0.0034 17.8 0.3 0.011 16.2 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain E1-E2_ATPase PF00122.15 KII85370.1 - 1.4e-47 161.6 4.5 2.1e-47 161.0 3.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KII85370.1 - 6.1e-28 98.7 2.0 1.3e-27 97.6 1.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII85370.1 - 3e-12 47.1 0.0 5.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KII85370.1 - 3.7e-06 26.9 0.0 8.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KII85370.1 - 0.00014 21.4 0.5 0.0011 18.6 0.4 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NACHT PF05729.7 KII85374.1 - 3.4e-11 43.0 0.0 6.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII85374.1 - 2.9e-05 24.1 0.1 0.00046 20.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII85374.1 - 0.00012 22.2 0.2 0.0007 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KII85374.1 - 0.00043 20.0 0.0 0.00068 19.3 0.0 1.4 1 1 0 1 1 1 1 NTPase NB-ARC PF00931.17 KII85374.1 - 0.0009 18.1 0.0 0.002 17.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KII85374.1 - 0.0022 18.1 0.1 0.0063 16.7 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KII85374.1 - 0.008 15.8 0.1 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase KaiC PF06745.8 KII85374.1 - 0.039 13.0 0.2 0.26 10.3 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA_17 PF13207.1 KII85374.1 - 0.083 13.7 0.4 0.32 11.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KII85374.1 - 0.1 12.4 0.0 0.64 9.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KII85374.1 - 0.12 12.6 0.3 0.41 10.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KII85374.1 - 0.15 11.6 0.1 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 KII85375.1 - 1.4e-194 623.9 72.3 5e-15 54.7 0.2 15.2 15 0 0 15 15 15 15 WD domain, G-beta repeat DUF3312 PF11768.3 KII85375.1 - 1.9e-22 79.2 1.4 0.0071 14.6 0.0 7.9 1 1 7 9 9 9 9 Protein of unknown function (DUF3312) PD40 PF07676.7 KII85375.1 - 1.6e-21 75.4 33.0 4.7 6.9 0.1 14.4 14 0 0 14 14 14 10 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 KII85375.1 - 5.4e-14 51.8 16.8 0.42 9.6 0.2 10.3 1 1 10 12 12 12 6 Protein of unknown function (DUF1258) DUF1652 PF07865.6 KII85375.1 - 1.7e-11 43.5 0.0 12 5.5 0.0 11.0 9 4 4 13 13 13 0 Protein of unknown function (DUF1652) RicinB_lectin_2 PF14200.1 KII85375.1 - 1.4e-10 41.4 12.0 1.5 9.2 0.1 8.6 1 1 12 13 13 13 4 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.11 KII85375.1 - 5.1e-09 34.9 20.2 0.025 12.8 0.3 6.9 1 1 7 8 8 8 8 Cytochrome D1 heme domain CelD_N PF02927.9 KII85375.1 - 2.4e-07 30.9 10.5 4.9 7.4 0.4 8.1 4 3 4 9 9 9 1 N-terminal ig-like domain of cellulase UN_NPL4 PF11543.3 KII85375.1 - 7.5e-05 22.9 8.2 2.5e+02 2.0 0.0 10.5 9 4 1 11 11 11 0 Nuclear pore localisation protein NPL4 SpoIIE PF07228.7 KII85375.1 - 0.00019 21.1 0.0 78 2.8 0.0 6.8 3 3 6 9 9 9 0 Stage II sporulation protein E (SpoIIE) PQQ_3 PF13570.1 KII85375.1 - 0.0041 17.3 34.1 19 5.6 0.1 11.9 10 4 4 14 14 13 0 PQQ-like domain YliH PF10799.3 KII85375.1 - 0.039 13.6 2.6 9.5 5.9 0.0 5.3 5 2 2 7 7 7 0 Biofilm formation protein (YliH/bssR) Med16 PF11635.3 KII85375.1 - 0.044 11.7 0.2 8.7 4.1 0.1 3.7 2 1 0 4 4 4 0 Mediator complex subunit 16 MAP65_ASE1 PF03999.7 KII85376.1 - 1.9e-61 208.4 5.0 4e-57 194.1 0.4 3.1 2 2 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) PAT1 PF09770.4 KII85376.1 - 3.2 5.8 27.1 5.5 5.0 18.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Synaptobrevin PF00957.16 KII85377.1 - 3.3e-34 116.3 2.6 3.8e-34 116.1 1.8 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 KII85377.1 - 0.02 13.5 0.8 0.025 13.2 0.6 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF515 PF04415.7 KII85377.1 - 0.044 12.0 0.5 0.046 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1191 PF06697.7 KII85377.1 - 0.052 12.3 0.2 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) NAD_binding_4 PF07993.7 KII85378.1 - 5.8e-25 87.6 0.0 7.8e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KII85378.1 - 3.6e-12 46.2 0.0 5.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII85378.1 - 7.6e-05 22.7 0.0 0.00023 21.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII85378.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KII85378.1 - 0.0016 17.2 0.0 0.0028 16.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KII85378.1 - 0.0074 15.9 0.3 0.013 15.1 0.2 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KII85378.1 - 0.18 10.6 0.2 11 4.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 KII85379.1 - 3.9e-26 91.4 0.0 5.1e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KII85379.1 - 1.2e-10 41.2 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII85379.1 - 3.6e-05 22.5 0.0 5.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KII85379.1 - 7.9e-05 22.6 0.0 0.00029 20.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KII85379.1 - 0.00045 20.2 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KII85379.1 - 0.029 14.0 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.19 KII85379.1 - 0.049 13.9 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII85380.1 - 1.2e-23 83.3 0.0 1.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KII85380.1 - 3e-11 43.2 0.0 4.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII85380.1 - 0.00013 22.0 0.0 0.00034 20.6 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII85380.1 - 0.0065 16.3 0.3 0.016 15.1 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KII85380.1 - 0.026 13.2 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KII85380.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 KII85380.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.20 KII85381.1 - 1.8e-74 250.1 0.0 3.2e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII85381.1 - 3.6e-42 144.2 0.0 5e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII85381.1 - 2.9e-12 46.1 0.0 4.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII85381.1 - 0.001 18.1 0.1 0.003 16.6 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-Di19 PF05605.7 KII85383.1 - 0.069 13.2 0.9 0.89 9.7 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KII85383.1 - 0.13 12.6 6.2 0.45 10.9 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KII85383.1 - 6 7.4 11.5 0.66 10.4 0.3 3.5 3 1 0 3 3 3 0 Zinc finger, C2H2 type DUF4223 PF13978.1 KII85384.1 - 0.0059 16.3 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Ribosomal_L24e PF01246.15 KII85385.1 - 8.3e-31 105.6 0.5 8.3e-31 105.6 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e MAD PF05557.8 KII85385.1 - 0.0012 16.9 1.2 0.0014 16.7 0.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein COX16 PF14138.1 KII85385.1 - 0.62 10.2 3.5 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Acetyltransf_3 PF13302.1 KII85386.1 - 3.2e-11 43.5 0.0 4.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII85386.1 - 2.5e-06 27.4 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KII85386.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Transposase_21 PF02992.9 KII85388.1 - 4.3e-13 48.8 0.0 7.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 PUL PF08324.6 KII85388.1 - 0.3 9.8 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 PUL domain zf-UBR PF02207.15 KII85393.1 - 1.4e-10 40.6 8.7 1.4e-10 40.6 6.0 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 KII85393.1 - 2.7e-07 30.1 0.7 2.7e-07 30.1 0.5 3.9 4 1 1 5 5 5 1 PHD-finger DHODB_Fe-S_bind PF10418.4 KII85393.1 - 3.5 7.1 8.0 5.6 6.5 0.6 2.9 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B EF-hand_1 PF00036.27 KII85394.1 - 3.1e-38 126.1 9.7 6.5e-10 37.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KII85394.1 - 2.5e-34 117.1 2.5 2.7e-17 62.6 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KII85394.1 - 2.5e-29 100.6 8.8 5.9e-13 48.2 0.1 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KII85394.1 - 2.6e-28 95.3 5.9 3e-09 35.9 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KII85394.1 - 3e-25 86.3 5.3 2e-06 26.8 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KII85394.1 - 5.8e-12 45.3 0.1 7.3e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KII85394.1 - 7.6e-07 28.8 0.7 0.033 13.9 0.1 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KII85394.1 - 7.8e-07 29.1 0.0 0.04 13.9 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KII85394.1 - 8.4e-06 25.3 0.0 0.44 10.2 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KII85394.1 - 1.5e-05 24.8 0.4 0.00019 21.3 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 KII85394.1 - 0.0016 17.8 1.9 0.0022 17.4 1.3 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 KII85394.1 - 0.0036 17.0 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 1 Transcription factor MotA, activation domain Caleosin PF05042.8 KII85394.1 - 0.0091 15.5 0.1 0.24 10.9 0.0 2.6 1 1 1 2 2 2 1 Caleosin related protein Poly_export PF02563.11 KII85394.1 - 0.09 12.5 0.1 11 5.8 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 KII85394.1 - 0.12 12.3 0.4 20 5.2 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF3349 PF11829.3 KII85394.1 - 0.14 12.6 0.1 15 6.0 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) WH1 PF00568.18 KII85395.1 - 2.7e-22 78.5 0.0 3.8e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 KII85395.1 - 8.3e-05 22.9 0.1 0.0002 21.7 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 KII85395.1 - 0.0067 15.9 0.1 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 WH2 motif DUF1681 PF07933.9 KII85395.1 - 0.075 12.5 0.5 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Exo_endo_phos PF03372.18 KII85398.1 - 0.069 13.0 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4340 PF14238.1 KII85398.1 - 0.072 12.7 0.0 4.5 6.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4340) RVT_1 PF00078.22 KII85400.1 - 0.00033 20.0 0.0 0.00035 19.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KII85402.1 - 0.0001 22.6 0.0 0.00016 22.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RGS PF00615.14 KII85405.1 - 5.8e-10 39.3 1.9 2.6e-05 24.3 0.2 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain OAD_beta PF03977.8 KII85405.1 - 0.043 12.5 0.8 0.078 11.7 0.6 1.4 1 1 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit L51_S25_CI-B8 PF05047.11 KII85406.1 - 9.2e-14 50.9 0.0 4.9e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lipid_DES PF08557.5 KII85406.1 - 0.098 11.9 0.1 0.29 10.3 0.1 1.7 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Polyketide_cyc2 PF10604.4 KII85407.1 - 7.8e-07 29.3 0.4 1.9e-06 28.0 0.3 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KII85407.1 - 0.00093 19.1 0.1 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SGL PF08450.7 KII85409.1 - 7.2e-25 87.7 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KII85409.1 - 0.0011 18.9 0.0 0.0045 16.9 0.0 2.1 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 KII85409.1 - 0.026 14.4 0.6 29 4.8 0.0 4.1 3 0 0 3 3 3 0 NHL repeat TPPK_C PF12555.3 KII85409.1 - 0.037 13.7 1.2 0.075 12.7 0.8 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Dynamin_N PF00350.18 KII85410.1 - 2.3e-13 50.3 0.0 7.3e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KII85410.1 - 4e-06 26.7 0.0 0.00097 19.0 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KII85410.1 - 0.00033 20.9 0.0 0.0015 18.7 0.0 2.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KII85410.1 - 0.0024 17.0 0.0 0.0065 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KII85410.1 - 0.025 14.5 0.1 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KII85410.1 - 0.042 13.9 0.2 0.45 10.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain IIGP PF05049.8 KII85410.1 - 0.045 12.5 0.0 1.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.1 KII85410.1 - 0.088 13.1 2.4 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SGL PF08450.7 KII85411.1 - 4.1e-27 95.1 0.0 6.4e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KII85411.1 - 0.002 18.0 0.2 0.0082 16.1 0.0 2.1 2 1 0 2 2 2 1 Arylesterase Str_synth PF03088.11 KII85411.1 - 0.074 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Strictosidine synthase DPPIV_N PF00930.16 KII85411.1 - 0.13 10.8 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DDE_1 PF03184.14 KII85412.1 - 2.1e-22 79.3 0.1 4.2e-22 78.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 KII85412.1 - 0.0042 16.8 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KII85412.1 - 0.0051 16.5 0.1 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FA_desaturase PF00487.19 KII85414.1 - 8.9e-15 54.8 20.2 8.9e-15 54.8 14.0 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KII85414.1 - 1.6e-11 43.8 0.0 3.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ORC6 PF05460.8 KII85415.1 - 0.23 10.4 9.4 0.42 9.6 6.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) APH PF01636.18 KII85420.1 - 3.6e-14 53.0 0.6 4.1e-14 52.8 0.4 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII85420.1 - 0.00048 19.7 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KII85420.1 - 0.0067 15.7 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family zf-Di19 PF05605.7 KII85422.1 - 0.017 15.2 2.0 0.017 15.2 1.4 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KII85422.1 - 0.023 15.0 11.8 0.072 13.4 2.3 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII85422.1 - 0.37 11.2 10.3 0.1 13.0 1.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KII85422.1 - 3.1 7.6 10.5 0.11 12.3 2.5 2.2 2 1 1 3 3 3 0 BED zinc finger APH PF01636.18 KII85423.1 - 0.023 14.4 0.0 0.027 14.1 0.0 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family cEGF PF12662.2 KII85425.1 - 3 7.5 8.0 1.8 8.2 0.2 3.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like SIS_2 PF13580.1 KII85427.1 - 0.11 12.2 0.5 0.85 9.3 0.1 2.0 1 1 1 2 2 2 0 SIS domain DNA_ligase_A_M PF01068.16 KII85429.1 - 1.7e-10 40.6 0.1 5.8 6.2 0.0 7.3 2 1 6 8 8 8 5 ATP dependent DNA ligase domain Antimicrobial_7 PF08102.6 KII85429.1 - 0.00078 19.4 4.8 11 6.1 0.0 7.1 6 1 1 7 7 7 1 Scorpion antimicrobial peptide Mre11_DNA_bind PF04152.9 KII85429.1 - 0.002 18.0 0.1 31 4.3 0.0 5.1 4 2 2 6 6 6 0 Mre11 DNA-binding presumed domain UPF0239 PF06783.6 KII85429.1 - 0.017 15.0 0.0 20 5.1 0.0 5.1 5 5 3 8 8 8 0 Uncharacterised protein family (UPF0239) MeMO_Hyd_G PF02964.11 KII85429.1 - 0.023 14.6 0.3 8.3 6.2 0.0 3.2 2 1 1 4 4 4 0 Methane monooxygenase, hydrolase gamma chain HD PF01966.17 KII85429.1 - 0.027 14.4 13.4 28 4.7 1.0 7.1 3 3 2 5 5 5 0 HD domain CcdA PF07362.7 KII85429.1 - 0.054 13.3 1.2 23 4.9 0.0 4.7 4 2 2 6 6 6 0 Post-segregation antitoxin CcdA Bacteriocin_IIi PF11758.3 KII85430.1 - 0.011 15.3 5.7 14 5.3 0.1 4.7 1 1 4 5 5 5 0 Aureocin-like type II bacteriocin NosD PF05048.8 KII85430.1 - 0.95 8.5 16.6 0.65 9.1 10.1 1.6 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Orbi_VP7 PF00897.12 KII85430.1 - 7.6 5.3 8.6 12 4.7 0.4 2.4 1 1 0 2 2 2 0 Orbivirus inner capsid protein VP7 Oxidored_FMN PF00724.15 KII85431.1 - 2e-68 230.8 0.0 2.6e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF619 PF04768.8 KII85432.1 - 8.5e-44 148.9 0.0 1.3e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KII85432.1 - 7.3e-28 97.3 0.0 1.9e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KII85432.1 - 2.1e-19 70.0 0.0 4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 KII85432.1 - 0.1 13.0 0.0 0.81 10.2 0.0 2.3 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Metallophos PF00149.23 KII85433.1 - 8.1e-42 142.8 0.9 1.2e-41 142.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.21 KII85434.1 - 1.9e-46 156.9 0.0 2.4e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII85434.1 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KII85434.1 - 0.0077 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KII85434.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Skp1_POZ PF03931.10 KII85435.1 - 0.00019 21.4 0.0 0.00037 20.5 0.0 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain SCF PF02404.10 KII85435.1 - 0.096 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor Glyco_hydro_92 PF07971.7 KII85438.1 - 2.6e-123 412.3 0.0 3.5e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 zf-RING_2 PF13639.1 KII85440.1 - 1.3e-13 50.5 6.1 1.8e-13 50.1 4.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII85440.1 - 2.1e-09 37.2 5.0 3e-09 36.7 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII85440.1 - 3.6e-08 32.9 2.4 5.8e-08 32.2 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85440.1 - 1.1e-07 31.4 3.4 1.6e-07 30.9 2.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII85440.1 - 1.3e-07 31.1 4.5 1.9e-07 30.6 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII85440.1 - 6.5e-07 29.3 6.9 2.1e-06 27.7 4.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger RINGv PF12906.2 KII85440.1 - 6e-05 23.0 6.2 0.0001 22.2 4.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 KII85440.1 - 0.00023 20.8 4.1 0.0011 18.5 0.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 KII85440.1 - 0.00063 19.5 6.1 0.0029 17.3 4.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KII85440.1 - 0.0024 17.4 4.5 0.011 15.3 3.1 1.9 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 KII85440.1 - 0.0094 15.6 3.8 0.17 11.6 0.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.24 KII85440.1 - 0.038 13.6 5.5 0.12 12.1 3.7 1.8 1 1 1 2 2 2 0 PHD-finger Rad50_zn_hook PF04423.9 KII85440.1 - 0.11 11.9 0.9 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif UPF0547 PF10571.4 KII85440.1 - 0.24 11.1 2.9 1 9.1 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_4 PF14447.1 KII85440.1 - 0.25 10.9 4.2 0.52 9.8 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KII85440.1 - 0.43 10.5 11.3 25 4.9 7.8 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_ligase_ZBD PF03119.11 KII85440.1 - 1.2 8.9 4.4 1.8 8.3 0.3 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-P11 PF03854.9 KII85440.1 - 1.2 8.6 8.2 0.27 10.7 1.4 2.1 1 1 0 2 2 2 0 P-11 zinc finger zf-RING-like PF08746.6 KII85440.1 - 2.3 8.2 6.8 0.85 9.6 2.0 2.0 2 0 0 2 2 2 0 RING-like domain SRP-alpha_N PF04086.8 KII85441.1 - 7.1 5.9 8.0 12 5.1 5.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hydantoinase_B PF02538.9 KII85442.1 - 9.4e-184 611.4 0.1 5.1e-183 609.0 0.0 1.8 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Glyco_hydro_71 PF03659.9 KII85444.1 - 3.9e-101 338.3 8.3 4.9e-101 338.0 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 zf-H2C2_2 PF13465.1 KII85446.1 - 3.8e-11 42.6 9.6 4.4e-08 33.0 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KII85446.1 - 2.2e-08 33.9 15.6 0.0038 17.4 0.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KII85446.1 - 1.7e-06 27.8 14.3 0.0069 16.5 0.0 4.1 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KII85446.1 - 0.017 15.4 14.6 0.22 11.9 0.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KII85446.1 - 0.56 10.4 3.6 1.3 9.3 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3505 PF12013.3 KII85446.1 - 3.9 7.7 8.3 1.4e+02 2.7 5.8 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) Glyco_hydro_71 PF03659.9 KII85447.1 - 9.4e-109 363.4 4.0 1.2e-108 363.0 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SAG PF04092.8 KII85447.1 - 0.023 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 SRS domain VHS PF00790.14 KII85448.1 - 6.8e-38 129.4 0.0 2.8e-37 127.4 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KII85448.1 - 1e-19 70.3 0.1 2.7e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 GAT domain HMG_box PF00505.14 KII85450.1 - 2e-14 53.5 7.6 2.3e-06 27.7 1.1 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KII85450.1 - 2.9e-10 40.3 4.8 2.4e-06 27.8 0.3 2.7 2 0 0 2 2 2 2 HMG-box domain Tol_Tol_Ttg2 PF05494.7 KII85450.1 - 0.069 12.6 3.4 3.3 7.2 0.3 2.5 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 Med3 PF11593.3 KII85450.1 - 4.1 6.5 8.1 4.9 6.2 5.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-C2H2 PF00096.21 KII85451.1 - 3.6e-07 30.1 17.3 0.011 16.0 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KII85451.1 - 3.6e-07 30.0 11.6 0.0048 17.0 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KII85451.1 - 1.9e-06 27.8 0.7 1.9e-06 27.8 0.5 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII85451.1 - 0.00016 21.7 15.2 0.46 10.9 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KII85451.1 - 0.96 9.6 9.2 0.75 9.9 2.5 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 KII85451.1 - 0.97 9.8 7.2 0.58 10.5 1.4 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 KII85451.1 - 1.9 8.7 4.9 1.4 9.1 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KII85451.1 - 2.1 8.3 7.5 0.76 9.7 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Glyco_hydro_71 PF03659.9 KII85452.1 - 8.7e-107 356.9 2.2 1.1e-106 356.6 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ThiF PF00899.16 KII85453.1 - 3.7e-39 133.6 0.0 6.9e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KII85453.1 - 7.1e-28 95.9 0.1 1.3e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KII85453.1 - 9.5e-20 69.7 1.8 1.9e-19 68.7 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KII85453.1 - 2.9e-07 30.4 0.0 6.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KII85453.1 - 0.00043 20.4 0.0 0.0039 17.4 0.0 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KII85453.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad17 PF03215.10 KII85455.1 - 2e-52 178.5 0.0 1.2e-51 176.0 0.0 1.8 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KII85455.1 - 0.00068 19.6 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KII85455.1 - 0.0071 16.0 0.4 0.021 14.5 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KII85455.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KII85455.1 - 0.015 15.4 0.1 0.036 14.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CTDII PF01556.13 KII85456.1 - 7.1e-12 45.0 0.0 3.5e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KII85456.1 - 0.00012 22.0 7.7 0.0016 18.4 1.1 2.3 2 0 0 2 2 2 2 DnaJ central domain CTDII PF01556.13 KII85458.1 - 1.6e-11 43.9 0.0 5.6e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KII85458.1 - 4.6e-07 29.7 11.9 1.5e-06 28.1 8.4 1.7 1 1 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 KII85458.1 - 0.016 14.6 2.0 0.016 14.6 1.4 2.6 2 1 1 3 3 3 0 A2L zinc ribbon domain HypA PF01155.14 KII85458.1 - 2.9 7.5 7.7 6.6 6.4 1.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 KII85458.1 - 4.9 6.9 10.0 0.86 9.4 0.6 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) 3-HAO PF06052.7 KII85459.1 - 1.6e-58 196.3 0.0 1.9e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KII85459.1 - 1.4e-06 27.6 0.2 2.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KII85459.1 - 0.00048 19.8 0.1 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain F-box-like PF12937.2 KII85460.1 - 2.2e-06 27.2 0.6 1.3e-05 24.7 0.4 2.2 1 1 0 1 1 1 1 F-box-like YL1_C PF08265.6 KII85461.1 - 1.5e-15 56.4 0.2 2.5e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BING4CT PF08149.6 KII85462.1 - 2.3e-34 116.7 0.0 2.1e-33 113.6 0.0 2.4 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KII85462.1 - 2.3e-09 36.7 0.0 4.5e-07 29.4 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KII85462.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.9 KII85462.1 - 0.043 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Glyoxal_oxid_N PF07250.6 KII85463.1 - 3e-41 141.1 0.0 5.4e-38 130.4 0.0 4.0 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KII85463.1 - 3.6e-23 81.4 0.3 7.6e-23 80.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 KII85463.1 - 0.0002 19.7 0.0 0.00029 19.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KII85463.1 - 0.0071 15.6 1.6 0.013 14.8 1.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.1 KII85463.1 - 0.013 15.7 0.1 0.085 13.0 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Kelch_4 PF13418.1 KII85463.1 - 0.16 11.7 19.2 0.26 11.0 0.1 5.9 6 0 0 6 6 6 0 Galactose oxidase, central domain Pkinase PF00069.20 KII85465.1 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII85465.1 - 0.00028 20.6 0.7 0.001 18.8 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KII85465.1 - 0.00089 18.3 0.1 0.18 10.8 0.0 2.2 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family CPL PF08144.6 KII85467.1 - 2.8e-22 79.1 1.4 1.2e-20 73.8 0.0 3.7 4 0 0 4 4 4 1 CPL (NUC119) domain zf-MYND PF01753.13 KII85468.1 - 2.2e-09 37.0 10.9 4.4e-09 36.0 7.5 1.5 1 0 0 1 1 1 1 MYND finger Dna2 PF08696.6 KII85469.1 - 9.8e-54 181.8 0.0 1.8e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KII85469.1 - 6.5e-50 169.3 0.0 1.1e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII85469.1 - 1.2e-19 70.8 0.0 2.1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII85469.1 - 1e-09 37.9 0.2 4.5e-09 35.9 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KII85469.1 - 2.6e-08 33.7 0.0 6.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 KII85469.1 - 3.6e-06 26.5 0.0 1.5e-05 24.5 0.0 2.0 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 KII85469.1 - 0.0014 18.5 0.9 0.14 12.1 0.6 2.7 1 1 0 1 1 1 1 Domain of unknown function DUF83 AAA_16 PF13191.1 KII85469.1 - 0.0024 17.8 0.0 0.0094 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.16 KII85469.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KII85469.1 - 0.011 15.3 0.1 0.94 8.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KII85469.1 - 0.011 15.4 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KII85469.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KII85469.1 - 0.016 14.6 0.1 0.044 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KII85469.1 - 0.022 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KII85469.1 - 0.024 14.0 0.5 0.047 13.1 0.1 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SE PF00437.15 KII85469.1 - 0.025 13.4 0.0 0.069 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Helicase_RecD PF05127.9 KII85469.1 - 0.029 14.0 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_33 PF13671.1 KII85469.1 - 0.043 13.6 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain CbiA PF01656.18 KII85469.1 - 0.055 12.8 0.1 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Whib PF02467.11 KII85469.1 - 0.12 12.6 2.0 10 6.4 0.1 2.7 2 0 0 2 2 2 0 Transcription factor WhiB Flavin_Reduct PF01613.13 KII85470.1 - 1.9e-20 73.2 0.0 2.5e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Myosin_head PF00063.16 KII85472.1 - 8.1e-241 800.8 0.0 5.9e-240 797.9 0.0 2.6 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KII85472.1 - 3.8e-41 140.7 302.0 1.3e-25 89.3 74.9 5.3 1 1 2 4 4 4 3 Myosin tail Ribosomal_L38e PF01781.13 KII85472.1 - 5.5e-30 102.9 1.9 8.1e-30 102.3 0.3 2.2 2 0 0 2 2 2 1 Ribosomal L38e protein family Myosin_N PF02736.14 KII85472.1 - 3.4e-07 29.8 2.4 8.5e-07 28.5 1.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KII85472.1 - 0.0013 18.3 48.9 0.0013 18.3 33.9 12.0 2 2 9 11 11 11 7 Intermediate filament protein AAA_22 PF13401.1 KII85472.1 - 0.0054 16.8 2.4 0.051 13.7 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KII85472.1 - 0.026 14.2 0.0 0.12 12.1 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain Pap_E4 PF02711.9 KII85474.1 - 1 10.2 3.6 0.75 10.6 0.5 2.0 2 0 0 2 2 2 0 E4 protein DUF1077 PF06417.7 KII85477.1 - 0.16 11.3 0.2 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) DUF1980 PF09323.5 KII85477.1 - 0.46 10.1 2.2 0.51 10.0 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1761 PF08570.5 KII85477.1 - 1.4 8.9 7.0 1.9 8.4 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1761) DUF2463 PF09591.5 KII85477.1 - 3.5 7.1 9.7 0.69 9.4 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Yip1 PF04893.12 KII85477.1 - 8.1 5.9 15.6 5 6.6 0.3 2.4 1 1 1 2 2 2 0 Yip1 domain DUF3483 PF11982.3 KII85478.1 - 0.27 10.5 3.9 0.18 11.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) Ubie_methyltran PF01209.13 KII85479.1 - 1.4e-05 24.3 0.0 0.00073 18.7 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KII85479.1 - 0.00094 18.9 0.0 0.013 15.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII85479.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII85480.1 - 7e-05 22.5 0.0 0.00022 20.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII85480.1 - 0.00044 20.6 0.0 0.00077 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII85480.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KII85480.1 - 0.034 14.5 0.0 0.073 13.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KII85480.1 - 0.088 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KII85481.1 - 1.8e-09 37.5 0.0 4.8e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII85481.1 - 8e-06 25.1 0.0 2.7e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KII85481.1 - 1.1e-05 25.6 0.0 3.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII85481.1 - 1.1e-05 25.7 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII85481.1 - 0.00023 20.8 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII85481.1 - 0.00071 20.0 0.0 0.0016 18.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII85481.1 - 0.0086 16.6 0.0 0.043 14.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain ORC5_C PF14630.1 KII85482.1 - 2.5e-54 184.5 0.0 3.7e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus BTB PF00651.26 KII85483.1 - 3.1e-05 23.9 0.0 5.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pyr_redox_dim PF02852.17 KII85484.1 - 1.7e-42 143.8 3.0 6.8e-41 138.7 0.1 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KII85484.1 - 3.2e-38 131.6 15.7 1.1e-36 126.5 10.9 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII85484.1 - 7.7e-21 74.2 9.9 2.8e-18 66.0 1.0 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII85484.1 - 3.1e-11 42.7 0.7 3.1e-11 42.7 0.5 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII85484.1 - 1.9e-10 40.4 12.8 3.9e-10 39.3 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII85484.1 - 6.3e-10 39.4 2.1 1.3e-06 28.6 0.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII85484.1 - 9.2e-10 38.4 2.0 0.00013 21.8 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KII85484.1 - 3.9e-07 29.3 0.4 0.02 13.7 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KII85484.1 - 5.6e-07 28.7 12.4 0.0066 15.3 0.1 4.0 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII85484.1 - 6.8e-07 28.4 2.8 6.8e-07 28.4 1.9 3.7 2 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.9 KII85484.1 - 2e-06 26.5 15.3 0.00025 19.6 0.8 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 KII85484.1 - 0.0002 20.5 6.7 0.00061 18.9 0.1 2.6 2 1 1 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.16 KII85484.1 - 0.00074 19.1 6.6 0.03 13.8 0.2 3.7 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KII85484.1 - 0.0019 17.2 10.7 0.15 11.0 0.4 3.4 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.14 KII85484.1 - 0.002 17.1 2.0 0.017 14.1 0.1 2.7 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.19 KII85484.1 - 0.12 11.4 0.2 0.38 9.7 0.1 1.7 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KII85484.1 - 0.39 10.3 7.0 0.042 13.5 0.7 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KII85484.1 - 0.69 8.7 6.8 0.58 9.0 0.1 3.0 3 1 0 3 3 3 0 Lycopene cyclase protein Pkinase PF00069.20 KII85486.1 - 8.2e-43 146.4 0.0 3.3e-42 144.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII85486.1 - 3.4e-25 88.6 0.0 1.4e-21 76.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KII85486.1 - 3.5e-06 26.9 0.1 0.012 15.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KII85486.1 - 0.00011 21.2 0.0 0.045 12.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.27 KII85487.1 - 6.2e-14 51.2 0.0 0.0002 21.1 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.2 KII85487.1 - 2.3e-06 27.1 2.5 2.5e-05 23.9 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII85487.1 - 1.9e-05 24.1 0.9 0.00012 21.6 0.1 2.4 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 KII85487.1 - 0.0039 16.6 0.0 2.4 7.5 0.1 2.9 2 1 1 3 3 3 2 PQQ-like domain p450 PF00067.17 KII85490.1 - 2.5e-64 217.5 0.0 6.2e-64 216.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KII85491.1 - 3.6e-07 29.6 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII85491.1 - 0.00017 21.3 0.6 0.0025 17.5 0.4 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII85491.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase GPI-anchored PF10342.4 KII85492.1 - 2.9e-08 34.0 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Beach PF02138.13 KII85493.1 - 7.6e-98 327.2 0.0 1.3e-97 326.5 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 KII85493.1 - 6.9e-09 35.2 6.8 0.051 13.4 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat PH_BEACH PF14844.1 KII85493.1 - 7e-09 35.4 0.0 1.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KII85493.1 - 1.9e-08 34.6 0.0 5.7e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KII85493.1 - 0.036 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Laminin G domain Pkinase PF00069.20 KII85494.1 - 5e-41 140.5 0.0 6.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII85494.1 - 1.4e-13 50.4 0.0 2.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII85494.1 - 0.00014 21.6 1.2 0.00059 19.6 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII85494.1 - 0.00088 18.3 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KII85494.1 - 0.021 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 KII85495.1 - 4.2e-52 176.7 0.0 6e-52 176.2 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KII85496.1 - 1.3e-11 44.6 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 KII85496.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KII85496.1 - 0.0051 16.8 0.8 0.015 15.3 0.1 2.2 2 1 0 2 2 2 1 NADH(P)-binding TT_ORF2 PF02957.10 KII85497.1 - 0.062 14.0 0.1 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 TT viral ORF2 Suc_Fer-like PF06999.7 KII85498.1 - 3.3e-27 96.0 0.1 2.6e-26 93.0 0.0 1.9 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Glyco_hyd_65N_2 PF14498.1 KII85499.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF972 PF06156.8 KII85500.1 - 0.28 11.5 0.0 0.28 11.5 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 KII85500.1 - 3.5 6.7 6.4 7.5 5.6 1.9 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Hemerythrin PF01814.18 KII85501.1 - 8.7e-12 45.3 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain YCII PF03795.9 KII85502.1 - 2.4e-11 43.6 0.0 2.8e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Myosin_tail_1 PF01576.14 KII85503.1 - 0.088 10.5 0.5 0.11 10.1 0.3 1.1 1 0 0 1 1 1 0 Myosin tail Pox_A_type_inc PF04508.7 KII85503.1 - 0.48 10.3 6.3 0.21 11.4 1.8 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat THRAP3_BCLAF1 PF15440.1 KII85503.1 - 6.9 5.2 11.8 8.9 4.8 8.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Profilin PF00235.14 KII85504.1 - 9.8e-39 132.2 0.3 1.1e-38 132.0 0.2 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.13 KII85507.1 - 2.8e-88 295.0 0.1 3.2e-88 294.9 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ABC_membrane PF00664.18 KII85509.1 - 1.2e-54 185.6 31.0 2.4e-29 102.6 8.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII85509.1 - 2.6e-53 179.9 0.0 2.1e-29 102.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII85509.1 - 5.7e-10 38.7 2.9 0.0039 16.4 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KII85509.1 - 2.7e-09 37.0 0.5 0.0062 16.4 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KII85509.1 - 6.8e-09 36.1 0.0 0.096 12.6 0.0 3.6 2 1 0 3 3 3 2 AAA domain Miro PF08477.8 KII85509.1 - 6.1e-08 33.1 0.1 0.014 15.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KII85509.1 - 7.2e-08 31.8 0.1 0.014 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KII85509.1 - 1.2e-07 31.8 0.4 0.0077 16.2 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KII85509.1 - 1.3e-06 27.9 0.1 0.0046 16.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KII85509.1 - 2.4e-06 26.8 0.1 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KII85509.1 - 5.8e-06 26.7 0.2 0.11 12.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KII85509.1 - 2.7e-05 23.7 0.1 0.054 12.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.18 KII85509.1 - 2.8e-05 24.0 3.7 0.028 14.2 0.2 3.3 3 0 0 3 3 3 2 Dynamin family AAA_22 PF13401.1 KII85509.1 - 3e-05 24.1 0.5 0.25 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KII85509.1 - 5.6e-05 22.3 0.3 0.18 10.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KII85509.1 - 9.6e-05 23.1 0.0 0.84 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KII85509.1 - 0.00012 22.0 0.1 0.65 9.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF815 PF05673.8 KII85509.1 - 0.00021 20.2 0.4 0.078 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.9 KII85509.1 - 0.00032 20.4 0.4 0.25 11.0 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KII85509.1 - 0.00049 19.6 0.0 0.2 11.1 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KII85509.1 - 0.00065 19.2 0.3 0.97 8.8 0.3 3.2 3 1 1 4 4 3 1 AAA-like domain Arch_ATPase PF01637.13 KII85509.1 - 0.00083 19.1 0.1 0.071 12.8 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 KII85509.1 - 0.0013 18.9 0.2 2.9 8.1 0.0 3.4 4 0 0 4 4 2 1 AAA domain NACHT PF05729.7 KII85509.1 - 0.0016 18.1 0.2 0.47 10.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.1 KII85509.1 - 0.0018 17.8 1.0 2.6 7.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain ArgK PF03308.11 KII85509.1 - 0.0024 16.6 0.5 1.1 8.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein cobW PF02492.14 KII85509.1 - 0.0027 17.1 0.9 0.67 9.3 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KII85509.1 - 0.0085 15.5 0.3 3.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KII85509.1 - 0.012 15.4 0.1 1.2 9.0 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KII85509.1 - 0.013 14.3 0.2 3.1 6.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.4 KII85509.1 - 0.017 13.7 0.2 0.97 7.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KAP_NTPase PF07693.9 KII85509.1 - 0.034 13.1 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain T2SE PF00437.15 KII85509.1 - 0.037 12.9 0.0 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KII85509.1 - 0.06 13.5 0.1 20 5.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.12 KII85509.1 - 0.077 12.5 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 KII85509.1 - 0.086 12.1 0.2 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein UPF0079 PF02367.12 KII85509.1 - 0.097 12.3 0.4 5.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 GTP_EFTU PF00009.22 KII85509.1 - 0.12 11.8 0.2 11 5.3 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.10 KII85509.1 - 0.13 12.0 0.2 31 4.2 0.0 3.2 4 0 0 4 4 4 0 NTPase AAA_15 PF13175.1 KII85509.1 - 0.2 10.6 0.0 17 4.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain zf-RING_2 PF13639.1 KII85511.1 - 3.5e-08 33.1 10.5 7.9e-08 32.0 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII85511.1 - 7.3e-08 31.9 6.6 1.3e-07 31.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85511.1 - 3.2e-07 29.9 8.4 5.7e-07 29.1 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII85511.1 - 3.3e-06 26.7 1.5 5.1e-06 26.0 0.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KII85511.1 - 9.3e-06 25.5 9.2 1.8e-05 24.6 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII85511.1 - 0.00013 21.5 7.8 0.00029 20.4 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85511.1 - 0.00029 20.6 6.9 0.00093 19.0 4.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KII85511.1 - 0.00057 19.4 6.0 0.001 18.5 4.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 KII85511.1 - 0.0014 17.9 0.4 0.0014 17.9 0.3 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-met PF12874.2 KII85511.1 - 0.011 15.9 0.1 0.011 15.9 0.1 2.5 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-RING_6 PF14835.1 KII85511.1 - 0.017 14.8 0.6 0.041 13.6 0.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AbiH PF14253.1 KII85511.1 - 0.063 12.8 0.6 0.085 12.4 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH PilJ PF13675.1 KII85511.1 - 0.065 13.5 1.9 0.12 12.7 1.3 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3348 PF11828.3 KII85511.1 - 0.078 12.3 3.4 0.11 11.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Mod_r PF07200.8 KII85511.1 - 0.13 12.1 2.3 0.2 11.5 1.6 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 KII85511.1 - 0.14 11.8 3.8 0.2 11.2 2.7 1.3 1 0 0 1 1 1 0 Mnd1 family Laminin_EGF PF00053.19 KII85511.1 - 0.18 11.7 4.3 3.4 7.6 0.6 2.6 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) FYVE PF01363.16 KII85511.1 - 0.19 11.6 6.2 6 6.8 4.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.2 KII85511.1 - 0.26 11.4 9.4 0.062 13.4 3.5 2.3 3 0 0 3 3 2 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 KII85511.1 - 0.3 10.8 1.9 0.71 9.5 1.3 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1272 PF06906.6 KII85511.1 - 0.32 10.8 4.6 0.29 10.9 1.8 2.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 KII85511.1 - 0.37 10.3 5.8 0.76 9.3 4.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IncA PF04156.9 KII85511.1 - 0.5 9.9 2.9 0.75 9.3 2.0 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_5 PF14634.1 KII85514.1 - 1.6e-09 37.3 7.6 3.1e-09 36.3 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII85514.1 - 8.1e-08 31.8 6.3 1.8e-07 30.7 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85514.1 - 1e-07 31.6 9.5 2.7e-07 30.2 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII85514.1 - 1.9e-06 27.7 5.6 5.1e-06 26.4 3.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII85514.1 - 4.9e-06 26.1 3.5 3.3e-05 23.5 2.4 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KII85514.1 - 1.1e-05 24.9 8.7 2.4e-05 23.8 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85514.1 - 0.00012 21.8 7.7 0.0016 18.3 5.8 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KII85514.1 - 0.0011 18.5 4.6 0.0027 17.2 3.2 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 KII85514.1 - 0.0015 18.3 0.8 0.0015 18.3 0.5 2.5 2 1 1 3 3 3 1 FYVE zinc finger Tropomyosin PF00261.15 KII85514.1 - 0.0016 17.5 6.2 0.0018 17.3 2.7 1.8 2 0 0 2 2 2 1 Tropomyosin DUF1272 PF06906.6 KII85514.1 - 0.014 15.2 6.9 0.19 11.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Baculo_IE-1 PF05290.6 KII85514.1 - 0.015 14.9 2.4 0.015 14.9 1.7 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 KII85514.1 - 0.026 13.7 4.9 0.051 12.7 3.4 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.2 KII85514.1 - 0.032 14.3 7.3 0.11 12.6 5.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KII85514.1 - 0.033 13.7 9.2 0.06 12.8 4.4 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2256 PF10013.4 KII85514.1 - 0.034 13.8 2.7 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_6 PF14835.1 KII85514.1 - 0.035 13.8 1.1 0.035 13.8 0.8 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Ferritin PF00210.19 KII85514.1 - 0.04 13.6 2.7 0.068 12.9 1.9 1.5 1 1 0 1 1 1 0 Ferritin-like domain Rad50_zn_hook PF04423.9 KII85514.1 - 0.056 12.9 0.8 0.056 12.9 0.5 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif FlgM PF04316.8 KII85515.1 - 0.042 13.7 0.1 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Acyltransferase PF01553.16 KII85516.1 - 9.5e-12 44.5 0.0 1.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase LOH1CR12 PF10158.4 KII85516.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Ribosomal_S11 PF00411.14 KII85517.1 - 4.3e-40 136.3 0.6 5.3e-40 136.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 RRM_1 PF00076.17 KII85518.1 - 2.3e-52 174.5 0.0 2.5e-14 52.6 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII85518.1 - 1.7e-42 143.2 0.0 1.7e-12 47.1 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII85518.1 - 8e-15 54.4 0.0 0.00055 19.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SEEEED PF14797.1 KII85518.1 - 4.3 7.4 30.8 0.96 9.5 16.1 2.6 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex ABC_membrane PF00664.18 KII85519.1 - 3.8e-55 187.2 34.2 4.2e-29 101.8 10.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII85519.1 - 1.2e-53 181.0 0.0 1.2e-30 106.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII85519.1 - 4.7e-10 39.0 2.3 0.0026 17.0 0.0 4.3 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII85519.1 - 7.5e-09 35.9 0.0 0.033 14.1 0.0 3.5 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KII85519.1 - 1.9e-08 34.2 0.1 0.011 15.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KII85519.1 - 4.5e-08 33.3 0.3 0.0053 16.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KII85519.1 - 9.6e-08 31.4 0.2 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KII85519.1 - 2.8e-07 31.0 0.7 0.038 14.4 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein Zeta_toxin PF06414.7 KII85519.1 - 2.1e-06 26.9 0.2 0.0067 15.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 KII85519.1 - 4e-06 26.4 0.1 0.021 14.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 KII85519.1 - 9.9e-06 26.0 0.5 0.11 12.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KII85519.1 - 1.2e-05 24.7 0.0 0.023 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KII85519.1 - 1.3e-05 24.4 0.3 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KII85519.1 - 4.6e-05 23.3 2.7 0.028 14.2 0.2 2.7 2 0 0 2 2 2 2 Dynamin family MobB PF03205.9 KII85519.1 - 0.00014 21.5 0.8 0.52 10.0 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KII85519.1 - 0.00014 22.6 0.0 0.84 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KII85519.1 - 0.00034 20.7 1.4 0.98 9.5 0.1 3.4 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 KII85519.1 - 0.00051 19.0 0.5 0.17 10.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.12 KII85519.1 - 0.0008 19.2 1.3 0.47 10.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 KII85519.1 - 0.001 19.3 0.4 2.7 8.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KII85519.1 - 0.0017 18.0 0.1 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.20 KII85519.1 - 0.0018 17.7 0.2 0.84 9.0 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 KII85519.1 - 0.0022 17.7 0.1 0.21 11.2 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_30 PF13604.1 KII85519.1 - 0.0032 17.0 1.6 2.8 7.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain ArgK PF03308.11 KII85519.1 - 0.0034 16.2 0.5 1.7 7.3 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 KII85519.1 - 0.0071 15.8 3.1 0.67 9.3 0.3 2.8 3 0 0 3 3 3 1 AAA-like domain PduV-EutP PF10662.4 KII85519.1 - 0.0078 15.7 0.2 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KII85519.1 - 0.008 15.6 0.8 0.96 8.8 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KII85519.1 - 0.014 15.6 0.1 2.4 8.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KII85519.1 - 0.021 13.7 0.1 3 6.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 KII85519.1 - 0.028 13.3 0.0 3.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 KII85519.1 - 0.029 13.0 0.3 2.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 KII85519.1 - 0.031 14.1 0.3 1.2 9.0 0.0 3.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.12 KII85519.1 - 0.041 13.4 0.2 9.9 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 KII85519.1 - 0.092 11.7 0.0 3 6.7 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KII85519.1 - 0.11 12.7 0.0 29 4.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase UPF0079 PF02367.12 KII85519.1 - 0.22 11.1 1.0 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 KII85519.1 - 0.24 10.3 0.0 9 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Sec61_beta PF03911.11 KII85520.1 - 9.6e-19 66.9 0.3 1.3e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 Sec61beta family Synaptobrevin PF00957.16 KII85521.1 - 2.9e-30 103.7 0.2 4.3e-30 103.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KII85521.1 - 2.8e-18 65.2 0.0 4.8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.4 KII85521.1 - 0.024 14.5 0.2 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein SET PF00856.23 KII85522.1 - 6.5e-10 39.5 0.1 8.9e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 SET domain DNA_pol_A_exo1 PF01612.15 KII85523.1 - 4.6e-10 39.2 0.0 8.8e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease Glyco_hydro_71 PF03659.9 KII85524.1 - 3.2e-96 322.1 11.7 3.8e-96 321.9 8.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4131 PF13567.1 KII85525.1 - 8.4 5.7 10.4 14 5.0 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) HTH_3 PF01381.17 KII85526.1 - 7.8e-09 35.2 0.0 8.7e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KII85526.1 - 2.2e-08 34.1 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KII85526.1 - 1.6e-06 28.0 0.0 1.9e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 KII85526.1 - 0.002 17.6 0.2 0.0035 16.9 0.0 1.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 KII85526.1 - 0.011 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 KII85526.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain KorB PF08535.5 KII85526.1 - 0.032 14.4 0.0 0.05 13.7 0.0 1.3 1 1 0 1 1 1 0 KorB domain Myb_DNA-bind_6 PF13921.1 KII85526.1 - 0.039 14.0 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KII85526.1 - 0.061 12.7 0.3 0.095 12.1 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2774 PF11242.3 KII85526.1 - 0.12 12.4 0.1 1.8 8.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2774) zf-RING_2 PF13639.1 KII85528.1 - 0.00058 19.6 16.4 0.0011 18.7 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain HlyD_2 PF12700.2 KII85528.1 - 0.002 17.3 0.5 0.0028 16.8 0.3 1.1 1 0 0 1 1 1 1 HlyD family secretion protein zf-C3HC4_2 PF13923.1 KII85528.1 - 0.0024 17.8 17.3 0.0044 17.0 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85528.1 - 0.0038 16.9 15.1 0.0069 16.0 10.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII85528.1 - 0.0041 16.7 16.0 0.0072 15.9 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII85528.1 - 0.028 13.9 10.2 0.052 13.1 7.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FlaC_arch PF05377.6 KII85528.1 - 0.032 14.1 2.8 0.22 11.4 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-RING_UBOX PF13445.1 KII85528.1 - 0.13 11.9 12.3 0.067 12.9 5.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KII85528.1 - 0.14 12.0 15.0 0.25 11.2 10.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Mto2_bdg PF12808.2 KII85528.1 - 0.21 11.7 3.6 0.62 10.2 1.2 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2057 PF09829.4 KII85528.1 - 0.37 10.4 3.7 0.93 9.1 2.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Baculo_IE-1 PF05290.6 KII85528.1 - 0.45 10.2 11.3 0.037 13.7 4.0 1.9 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) DUF4618 PF15397.1 KII85528.1 - 0.65 9.2 7.3 1.5 8.1 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Mod_r PF07200.8 KII85528.1 - 0.82 9.5 8.2 0.27 11.1 2.2 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 KII85528.1 - 1.7 8.2 4.8 0.59 9.6 0.8 2.0 2 1 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KII85528.1 - 2.4 8.5 5.1 1.8 8.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Costars PF14705.1 KII85529.1 - 4.3e-25 87.5 0.0 4.8e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Costars p450 PF00067.17 KII85530.1 - 5.1e-73 246.1 0.0 6.3e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GLE1 PF07817.8 KII85531.1 - 1.3e-35 122.5 0.0 4.9e-35 120.6 0.0 1.9 1 1 0 1 1 1 1 GLE1-like protein Lactonase PF10282.4 KII85533.1 - 1.8e-38 132.4 0.0 2.1e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller adh_short PF00106.20 KII85534.1 - 1.8e-31 109.3 2.1 2.7e-31 108.7 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII85534.1 - 1e-21 77.8 0.7 1.2e-21 77.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII85534.1 - 3.7e-12 46.2 0.7 6.7e-12 45.4 0.5 1.5 1 1 0 1 1 1 1 KR domain HHH_5 PF14520.1 KII85534.1 - 0.0075 16.4 2.2 1.2 9.4 0.8 2.6 2 1 0 2 2 2 2 Helix-hairpin-helix domain NAD_binding_10 PF13460.1 KII85534.1 - 0.088 12.8 0.6 0.21 11.5 0.4 1.8 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KII85534.1 - 0.094 12.1 0.2 0.12 11.7 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SNARE PF05739.14 KII85535.1 - 2.6e-07 30.2 0.1 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 SNARE domain DUF1515 PF07439.6 KII85535.1 - 0.11 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) NAD_binding_6 PF08030.7 KII85536.1 - 3e-20 72.7 0.0 2.3e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KII85536.1 - 2e-15 56.5 0.0 2.2e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 KII85536.1 - 4e-15 56.0 8.8 1.2e-14 54.4 6.1 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component 2TM PF13239.1 KII85536.1 - 0.34 10.9 4.7 24 5.0 2.4 2.8 2 0 0 2 2 2 0 2TM domain NAD_binding_6 PF08030.7 KII85537.1 - 4.7e-20 72.0 0.0 7.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KII85537.1 - 1.4e-15 57.4 8.4 3.6e-15 56.1 5.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KII85537.1 - 2.2e-14 53.1 0.1 2e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 KII85537.1 - 0.0058 17.1 0.0 0.56 10.7 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF393 PF04134.7 KII85537.1 - 0.19 12.8 2.1 1.4 10.0 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF393 Oxidored_FMN PF00724.15 KII85538.1 - 5.7e-99 331.3 0.0 6.5e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CAP59_mtransfer PF11735.3 KII85539.1 - 1.2e-56 191.6 0.0 1.7e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF336 PF03928.9 KII85541.1 - 1.2e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) GTF2I PF02946.9 KII85542.1 - 0.032 14.0 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 GTF2I-like repeat DUF336 PF03928.9 KII85543.1 - 2.2e-09 37.2 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) UQ_con PF00179.21 KII85544.1 - 1.3e-39 134.8 0.0 1.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KII85544.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain Hex_IIIa PF02455.11 KII85544.1 - 0.57 8.8 2.1 0.73 8.4 1.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) OPT PF03169.10 KII85546.1 - 1.4e-181 605.1 58.1 1.6e-181 604.9 40.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.6 KII85546.1 - 3.6 7.6 12.5 1.7 8.6 5.4 2.9 3 0 0 3 3 3 0 SigmaK-factor processing regulatory protein BofA ThiF PF00899.16 KII85547.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family ParA PF10609.4 KII85548.1 - 6e-31 106.1 0.1 1.2e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KII85548.1 - 3.1e-22 78.9 0.0 4.3e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KII85548.1 - 6.4e-09 35.9 0.2 2e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KII85548.1 - 3.1e-07 29.7 0.1 4.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KII85548.1 - 2.2e-06 26.9 0.2 0.0001 21.4 0.3 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 KII85548.1 - 0.0018 17.1 0.3 0.0027 16.5 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 KII85548.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KII85548.1 - 0.0029 16.8 0.1 0.0077 15.4 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KII85548.1 - 0.0059 16.2 0.1 0.36 10.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain VirC1 PF07015.6 KII85548.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein APS_kinase PF01583.15 KII85548.1 - 0.046 13.3 0.1 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.9 KII85548.1 - 0.049 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YhjQ PF06564.7 KII85548.1 - 0.072 12.4 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 YhjQ protein L_biotic_typeA PF04604.8 KII85550.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic Sld5 PF05916.6 KII85551.1 - 0.00033 20.9 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein LysM PF01476.15 KII85553.1 - 3.6e-12 45.9 0.3 4.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 LysM domain UCR_Fe-S_N PF10399.4 KII85553.1 - 0.089 11.9 1.0 0.18 11.0 0.7 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal zf-C2H2_4 PF13894.1 KII85557.1 - 0.0014 18.8 6.6 0.011 16.0 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII85557.1 - 0.25 11.7 3.7 0.35 11.3 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII85558.1 - 4e-05 23.6 7.6 0.011 15.9 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII85558.1 - 0.44 10.9 10.8 1.6 9.2 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L14 PF00238.14 KII85559.1 - 6.9e-34 116.2 0.0 7.8e-34 116.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.17 KII85560.1 - 2e-16 59.3 0.0 2.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII85560.1 - 1.9e-13 50.1 0.0 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII85560.1 - 2.6e-10 39.9 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KII85560.1 - 0.0022 17.6 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Aldo_ket_red PF00248.16 KII85561.1 - 5.7e-43 146.7 0.0 9.3e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HSP20 PF00011.16 KII85562.1 - 5e-15 55.2 0.1 3.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family HSP20 PF00011.16 KII85563.1 - 7.3e-16 57.8 0.1 1.2e-15 57.2 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Catalase PF00199.14 KII85564.1 - 2.3e-174 579.5 0.4 2.8e-174 579.2 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KII85564.1 - 1.9e-16 59.6 0.5 3.7e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Nrap PF03813.9 KII85565.1 - 2.5e-222 740.3 0.0 3e-222 740.0 0.0 1.1 1 0 0 1 1 1 1 Nrap protein WD40 PF00400.27 KII85566.1 - 6.1e-10 38.5 15.5 1.2e-06 28.1 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat CMAS PF02353.15 KII85568.1 - 1.9e-67 227.2 0.2 2.3e-67 226.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KII85568.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII85568.1 - 1.5e-10 41.3 0.0 1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII85568.1 - 5.6e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII85568.1 - 3.9e-06 27.1 0.0 9.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII85568.1 - 5.8e-06 26.3 0.0 1.8e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII85568.1 - 9.2e-06 26.2 0.0 2.9e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII85568.1 - 2.1e-05 24.1 0.0 5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 KII85568.1 - 4.9e-05 22.7 0.0 0.00015 21.1 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.9 KII85568.1 - 6.5e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KII85568.1 - 0.00092 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KII85568.1 - 0.041 12.9 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KII85568.1 - 0.099 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YIF1 PF03878.10 KII85569.1 - 8.2e-81 270.6 1.0 1e-80 270.3 0.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KII85569.1 - 6.6e-06 25.7 1.5 1.1e-05 24.9 1.0 1.3 1 0 0 1 1 1 1 Yip1 domain Cu_amine_oxid PF01179.15 KII85572.1 - 1.9e-51 175.1 0.8 2.8e-23 82.3 0.0 3.7 2 2 1 3 3 3 3 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KII85572.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hyd_65N_2 PF14498.1 KII85573.1 - 1.9e-37 129.1 0.2 5.1e-37 127.8 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Epimerase PF01370.16 KII85574.1 - 2.8e-16 59.7 0.0 4.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII85574.1 - 7.7e-10 37.9 0.1 1.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KII85574.1 - 7.4e-09 34.8 0.7 1.8e-07 30.3 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KII85574.1 - 1.5e-07 31.6 0.9 2.9e-07 30.6 0.6 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII85574.1 - 1.1e-06 28.6 2.4 4.6e-06 26.6 1.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KII85574.1 - 3.2e-05 23.2 1.2 5.4e-05 22.5 0.8 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KII85574.1 - 5.9e-05 22.0 0.1 8.8e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KII85574.1 - 0.0014 18.3 3.2 0.0074 15.9 2.1 2.1 1 1 0 1 1 1 1 KR domain FTSW_RODA_SPOVE PF01098.14 KII85575.1 - 0.14 10.9 6.7 0.17 10.5 4.6 1.2 1 0 0 1 1 1 0 Cell cycle protein Ninjurin PF04923.7 KII85575.1 - 0.36 10.5 3.1 0.92 9.2 2.2 1.6 1 1 0 1 1 1 0 Ninjurin Glyco_hydro_16 PF00722.16 KII85577.1 - 3.3e-20 72.1 0.5 6.7e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 KII85578.1 - 3.7e-51 173.5 1.6 3.7e-51 173.5 1.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KII85578.1 - 1.5e-09 38.0 0.0 1.8e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KII85578.1 - 0.00085 19.0 0.0 0.0084 15.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KII85578.1 - 0.051 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF842 PF05811.8 KII85578.1 - 0.3 10.5 0.1 0.64 9.4 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Helicase_C PF00271.26 KII85582.1 - 4.8e-17 61.5 0.0 1.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII85582.1 - 9.3e-17 61.0 0.0 1.6e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII85582.1 - 2.3e-05 24.3 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KII85582.1 - 0.0056 15.5 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 KII85582.1 - 0.052 12.8 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain SPX PF03105.14 KII85587.1 - 2.2e-22 80.1 0.0 4.5e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 KII85587.1 - 1.8e-06 27.4 10.7 2.8e-06 26.8 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII85587.1 - 7.5e-06 25.5 9.1 1.2e-05 24.9 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85587.1 - 1.1e-05 25.1 11.9 1.8e-05 24.4 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII85587.1 - 2.9e-05 23.8 11.8 4.8e-05 23.1 8.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KII85587.1 - 3.3e-05 23.8 12.7 5.2e-05 23.1 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85587.1 - 0.0007 19.2 10.6 0.0012 18.5 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII85587.1 - 0.0043 16.7 9.4 0.011 15.4 6.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KII85587.1 - 0.021 14.3 7.0 0.042 13.4 4.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KII85587.1 - 0.27 11.0 5.3 0.52 10.1 3.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KII85587.1 - 1.9 8.6 8.1 4.2 7.5 5.6 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KII85587.1 - 4.8 6.7 9.5 15 5.2 6.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Acetyltransf_1 PF00583.19 KII85588.1 - 2.1e-11 43.6 0.0 5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mss4 PF04421.8 KII85588.1 - 1.8e-08 34.1 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_7 PF13508.1 KII85588.1 - 2.3e-06 27.6 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII85588.1 - 0.0001 22.1 0.1 0.00026 20.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII85588.1 - 0.00084 19.0 0.0 0.0025 17.5 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KII85588.1 - 0.0021 18.1 0.0 0.0063 16.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII85588.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KII85588.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase IBR PF01485.16 KII85588.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 IBR domain F-box-like PF12937.2 KII85589.1 - 4.4e-08 32.7 2.6 9.3e-08 31.6 1.8 1.6 1 0 0 1 1 1 1 F-box-like Asp PF00026.18 KII85590.1 - 1.8e-51 175.3 15.9 4.7e-51 173.9 11.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII85590.1 - 1.7e-05 24.8 8.0 0.00015 21.7 4.4 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII85590.1 - 3.5e-05 24.2 7.3 0.013 15.9 1.0 2.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KII85590.1 - 0.008 15.9 0.3 0.45 10.3 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KII85590.1 - 0.052 13.0 0.1 0.89 9.0 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal RVP PF00077.15 KII85590.1 - 0.053 13.4 1.1 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Pkinase PF00069.20 KII85591.1 - 1.3e-70 237.5 0.0 1.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII85591.1 - 5.5e-34 117.4 0.0 7.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KII85591.1 - 5.5e-11 42.8 1.8 5.5e-11 42.8 1.2 2.2 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 KII85591.1 - 0.0019 17.2 0.0 0.0039 16.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII85591.1 - 0.031 14.0 0.1 0.057 13.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KII85591.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KII85593.1 - 5.1e-10 38.9 2.1 5.1e-10 38.9 1.4 2.0 2 0 0 2 2 2 1 F-box-like CALCOCO1 PF07888.6 KII85593.1 - 0.0057 14.9 0.1 0.0077 14.5 0.0 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like F-box-like_2 PF13013.1 KII85593.1 - 0.21 11.3 2.6 0.48 10.1 1.0 2.0 1 1 1 2 2 2 0 F-box-like domain F-box PF00646.28 KII85593.1 - 0.5 10.0 5.0 9.8 5.9 0.4 3.2 3 0 0 3 3 3 0 F-box domain rRNA_proc-arch PF13234.1 KII85594.1 - 6.9e-97 323.8 0.0 9.9e-97 323.2 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KII85594.1 - 7.5e-59 197.9 1.3 9.7e-59 197.6 0.2 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KII85594.1 - 1.7e-21 76.4 0.0 3.8e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII85594.1 - 1.3e-07 31.3 0.0 3.2e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KII85594.1 - 0.007 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KII85594.1 - 0.044 13.6 0.0 0.51 10.1 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KII85594.1 - 0.079 13.0 0.0 0.36 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KII85594.1 - 0.12 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_18 PF00704.23 KII85595.1 - 9.8e-84 281.7 13.2 1.5e-83 281.0 9.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 KII85595.1 - 5.3e-08 32.3 12.1 5.3e-08 32.3 8.4 2.4 1 1 1 2 2 2 1 Carbohydrate binding domain Asp PF00026.18 KII85597.1 - 1.8e-23 83.2 0.0 2.9e-21 76.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII85597.1 - 0.034 14.0 0.2 9.4 6.1 0.1 2.5 1 1 0 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KII85597.1 - 0.089 12.6 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease F-box-like PF12937.2 KII85598.1 - 3.2e-06 26.7 0.2 1e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII85598.1 - 1.5e-05 24.5 0.2 4.9e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 F-box domain Ras PF00071.17 KII85599.1 - 2.4e-34 118.0 0.3 2.8e-34 117.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII85599.1 - 2.3e-23 82.9 0.1 8.4e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KII85599.1 - 6.8e-08 31.9 0.1 8.7e-08 31.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII85599.1 - 7.7e-08 31.7 0.2 9.6e-08 31.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KII85599.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KII85599.1 - 0.012 14.3 0.4 0.034 12.8 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit DLIC PF05783.6 KII85599.1 - 0.059 12.0 0.0 5.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.4 KII85599.1 - 0.13 11.7 0.3 0.56 9.6 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GMC_oxred_N PF00732.14 KII85600.1 - 3e-17 62.7 0.0 7.1e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII85600.1 - 8.2e-16 58.5 0.0 1.9e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KII85600.1 - 7.8e-06 25.0 0.1 0.0021 17.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KII85600.1 - 1.4e-05 24.3 0.0 0.0012 18.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KII85600.1 - 1.7e-05 23.8 0.0 0.00032 19.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KII85600.1 - 6.9e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII85600.1 - 0.00016 21.6 0.2 0.00055 19.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KII85600.1 - 0.00018 20.0 0.1 0.00027 19.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KII85600.1 - 0.0012 18.8 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KII85600.1 - 0.0015 17.6 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KII85600.1 - 0.019 15.0 0.1 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII85600.1 - 0.095 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A vATP-synt_E PF01991.13 KII85601.1 - 3.2e-54 183.2 9.9 3.7e-54 183.0 6.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ribosomal_S2 PF00318.15 KII85601.1 - 0.088 12.0 0.4 0.13 11.4 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 VIT1 PF01988.14 KII85601.1 - 0.81 9.1 2.9 1.2 8.5 2.0 1.2 1 0 0 1 1 1 0 VIT family DUF2461 PF09365.5 KII85602.1 - 1.5e-66 223.8 0.2 2.7e-66 223.0 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) FLO_LFY PF01698.11 KII85602.1 - 5.7 5.6 7.7 7.7 5.2 5.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC27 PF09507.5 KII85602.1 - 9.8 5.2 23.0 13 4.9 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paf67 PF10255.4 KII85604.1 - 1.3e-147 491.9 0.0 1.6e-147 491.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KII85604.1 - 0.0093 15.8 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII85604.1 - 0.07 12.7 0.1 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Carbpep_Y_N PF05388.6 KII85604.1 - 0.15 12.2 0.9 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide RF-1 PF00472.15 KII85605.1 - 8.1e-37 125.5 4.1 1.3e-36 124.9 2.8 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KII85605.1 - 1.2e-27 95.8 0.0 2.6e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 PCRF domain DUF221 PF02714.10 KII85606.1 - 9.6e-102 340.1 20.1 9.6e-102 340.1 14.0 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KII85606.1 - 2.2e-37 128.0 3.6 2.2e-37 128.0 2.5 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KII85606.1 - 3.1e-13 50.0 0.0 1.8e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) EF-hand_7 PF13499.1 KII85608.1 - 4.1e-13 49.2 0.0 4.5e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KII85608.1 - 6e-12 44.3 0.3 6.3e-05 22.5 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KII85608.1 - 1.8e-10 39.2 0.1 0.00046 19.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KII85608.1 - 1.8e-07 30.6 0.1 0.00014 21.4 0.0 3.4 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.1 KII85608.1 - 1.9e-06 27.6 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KII85608.1 - 0.0064 15.7 0.2 1.5 8.2 0.0 2.6 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.8 KII85608.1 - 0.0098 15.4 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Amidohydro_4 PF13147.1 KII85608.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase UBX PF00789.15 KII85609.1 - 2.1e-06 27.7 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KII85609.1 - 0.00036 20.0 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain ARGLU PF15346.1 KII85609.1 - 0.11 12.3 23.5 0.17 11.6 16.3 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CBM_20 PF00686.14 KII85613.1 - 6.3e-53 176.3 7.0 1.1e-26 92.2 0.3 2.8 3 0 0 3 3 3 2 Starch binding domain Alpha-amylase PF00128.19 KII85613.1 - 1.6e-19 70.4 0.0 3.5e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KII85613.1 - 1.1e-07 31.8 0.0 5e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Tetraspannin PF00335.15 KII85614.1 - 0.024 13.9 13.9 0.055 12.7 8.4 1.9 1 1 1 2 2 2 0 Tetraspanin family DUF4235 PF14019.1 KII85614.1 - 0.76 9.6 4.4 0.59 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) ABC2_membrane_2 PF12679.2 KII85614.1 - 4.5 6.0 11.2 1.4 7.7 5.6 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF202 PF02656.10 KII85614.1 - 7 6.9 6.8 2.9 8.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4134 PF13572.1 KII85614.1 - 7.8 6.6 8.4 7.4 6.7 2.7 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4134) EKR PF10371.4 KII85615.1 - 1.2 8.7 27.0 27 4.4 0.1 7.7 8 0 0 8 8 8 0 Domain of unknown function Flavin_Reduct PF01613.13 KII85616.1 - 4.5e-22 78.5 0.0 6.1e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Cupin_5 PF06172.6 KII85617.1 - 7.5e-23 80.9 0.0 9.1e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Longin PF13774.1 KII85618.1 - 6e-18 64.1 0.0 9.9e-18 63.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KII85618.1 - 6.7e-15 54.4 1.1 1.1e-14 53.8 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KII85618.1 - 0.12 12.1 0.2 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 An_peroxidase PF03098.10 KII85619.1 - 8.5e-74 248.8 0.0 1.7e-71 241.2 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase Ashwin PF15323.1 KII85620.1 - 7.4 6.5 10.8 38 4.1 7.4 1.9 1 1 0 1 1 1 0 Developmental protein NAD_binding_6 PF08030.7 KII85621.1 - 1.3e-18 67.4 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KII85621.1 - 2.6e-14 52.9 0.0 1.2e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 KII85621.1 - 0.015 15.8 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain MHC_I_C PF06623.6 KII85622.1 - 0.079 12.4 2.8 0.15 11.5 2.0 1.4 1 0 0 1 1 1 0 MHC_I C-terminus FHA PF00498.21 KII85624.1 - 3.3e-14 52.7 0.0 5.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KII85624.1 - 2.6e-09 36.7 10.9 4.5e-09 35.9 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII85624.1 - 1.4e-06 28.3 2.4 2.6e-06 27.4 1.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KII85624.1 - 5.8e-05 22.6 10.4 9.4e-05 21.9 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII85624.1 - 0.00041 20.1 2.2 0.00074 19.3 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KII85624.1 - 0.0063 16.1 6.8 0.011 15.3 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85624.1 - 0.0085 15.7 9.0 0.014 15.0 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 KII85624.1 - 0.0095 15.6 5.0 0.016 14.8 3.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 KII85624.1 - 0.011 15.6 11.5 0.019 14.9 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNase_P_p30 PF01876.11 KII85625.1 - 5.5e-27 93.8 0.0 1.3e-26 92.6 0.0 1.6 2 0 0 2 2 2 1 RNase P subunit p30 E1-E2_ATPase PF00122.15 KII85628.1 - 9e-23 80.5 0.1 2.6e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KII85628.1 - 4.3e-21 76.3 0.0 4.2e-20 73.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII85628.1 - 8.3e-19 68.4 0.0 1.7e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII85628.1 - 8.5e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KII85628.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KII85628.1 - 0.043 13.1 0.1 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Septin PF00735.13 KII85629.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Septin Pkinase PF00069.20 KII85630.1 - 0.056 12.5 0.0 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain HTH_AsnC-type PF13404.1 KII85631.1 - 0.036 13.5 1.5 2 8.0 0.1 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF3469 PF11952.3 KII85631.1 - 0.049 13.3 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) ADC PF06314.6 KII85632.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) F-box-like PF12937.2 KII85633.1 - 5.5e-08 32.4 0.4 1.3e-07 31.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like Ribosomal_L1 PF00687.16 KII85634.1 - 3.7e-50 170.2 3.5 4.6e-50 170.0 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family E1-E2_ATPase PF00122.15 KII85635.1 - 6.7e-14 51.4 0.0 6.7e-14 51.4 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KII85635.1 - 1.3e-12 48.2 0.2 2e-11 44.4 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII85635.1 - 2.3e-12 46.7 0.0 4.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KII85635.1 - 4.4e-12 46.8 0.5 1.3e-10 42.0 0.3 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KII85635.1 - 0.0044 16.6 0.0 0.041 13.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 KII85637.1 - 4.1e-22 78.2 0.0 6.8e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85637.1 - 1.7e-09 37.4 12.0 3.8e-09 36.2 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.18 KII85638.1 - 2.1e-33 113.5 0.0 6.4e-12 44.6 0.0 6.8 7 0 0 7 7 7 5 Ubiquitin family Rad60-SLD PF11976.3 KII85638.1 - 1.3e-11 44.0 0.0 6.4e-05 22.5 0.0 4.7 5 0 0 5 5 5 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KII85638.1 - 9.6e-06 25.7 1.4 2.2 8.6 0.0 6.4 5 2 0 5 5 5 1 Ubiquitin-like domain YukD PF08817.5 KII85638.1 - 1.4e-05 25.5 0.4 4.4 7.9 0.0 5.2 5 1 0 5 5 5 2 WXG100 protein secretion system (Wss), protein YukD Solute_trans_a PF03619.11 KII85639.1 - 2.9e-96 321.9 7.2 3.5e-96 321.7 5.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFS_1 PF07690.11 KII85640.1 - 4.5e-40 137.4 34.2 4.5e-40 137.4 23.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII85640.1 - 3.3e-17 62.2 7.9 3.3e-17 62.2 5.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Aldo_ket_red PF00248.16 KII85641.1 - 4.8e-59 199.4 0.0 5.6e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 KII85641.1 - 0.082 11.4 0.0 0.5 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) Redoxin PF08534.5 KII85642.1 - 7.7e-37 126.0 0.0 8.7e-37 125.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KII85642.1 - 3.5e-11 42.8 0.0 3.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glyco_hydro_76 PF03663.9 KII85643.1 - 4.2e-31 108.6 21.3 3.9e-27 95.6 2.8 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Ndc1_Nup PF09531.5 KII85644.1 - 1.2e-41 142.9 0.0 1.7e-41 142.3 0.0 1.2 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TRAM_LAG1_CLN8 PF03798.11 KII85645.1 - 4.8e-06 26.2 20.4 4.8e-06 26.2 14.1 1.5 1 1 0 1 1 1 1 TLC domain OTT_1508_deam PF14441.1 KII85646.1 - 0.00094 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase OTT_1508_deam PF14441.1 KII85647.1 - 0.00038 20.2 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Ins_allergen_rp PF06757.8 KII85647.1 - 0.15 11.4 0.1 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Asp PF00026.18 KII85648.1 - 9e-36 123.7 0.0 1.1e-17 64.3 1.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII85648.1 - 8e-05 23.0 0.8 0.067 13.7 0.3 3.4 2 1 0 2 2 2 2 Aspartyl protease Mito_carr PF00153.22 KII85649.1 - 3.6e-56 186.8 0.4 5.1e-18 64.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Pex19 PF04614.7 KII85650.1 - 3.6e-53 180.7 0.1 1.1e-52 179.2 0.0 1.6 2 0 0 2 2 2 1 Pex19 protein family DUF935 PF06074.7 KII85650.1 - 0.045 12.4 5.1 1.5 7.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF935) RGCC PF15151.1 KII85650.1 - 0.28 11.6 2.2 8.3 6.8 0.0 2.8 3 0 0 3 3 3 0 Response gene to complement 32 protein family DUF2360 PF10152.4 KII85650.1 - 7.3 6.8 9.5 15 5.8 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) NAD_binding_4 PF07993.7 KII85651.1 - 1e-31 109.7 0.0 1.7e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII85651.1 - 1.3e-18 66.6 0.0 2.4e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KII85651.1 - 4.1e-08 32.9 0.0 8.5e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KII85651.1 - 0.00081 19.6 0.1 0.004 17.3 0.1 2.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KII85651.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KII85651.1 - 0.0026 16.5 0.0 0.0051 15.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII85651.1 - 0.003 17.5 0.0 0.078 12.9 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding AMP-binding PF00501.23 KII85652.1 - 0.0097 14.3 0.0 0.011 14.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1992 PF09350.5 KII85653.1 - 0.14 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) Abhydrolase_6 PF12697.2 KII85654.1 - 6e-24 85.1 4.2 6e-24 85.1 2.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII85654.1 - 2.4e-05 24.0 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family CBM_2 PF00553.14 KII85654.1 - 0.035 14.1 0.7 0.88 9.6 0.3 2.2 2 0 0 2 2 2 0 Cellulose binding domain Methyltransf_11 PF08241.7 KII85655.1 - 1.3e-18 67.2 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII85655.1 - 2.1e-12 47.3 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII85655.1 - 6.5e-12 45.7 0.0 1.5e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII85655.1 - 6.5e-11 42.0 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII85655.1 - 3.1e-10 40.6 0.0 5.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII85655.1 - 1.4e-07 31.3 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII85655.1 - 5.9e-06 25.5 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KII85655.1 - 2.3e-05 24.3 0.1 5.7e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII85655.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Fer2_3 PF13085.1 KII85656.1 - 2.6e-33 114.1 0.0 3.8e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KII85656.1 - 5.6e-11 42.6 7.3 5.6e-11 42.6 5.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KII85656.1 - 1.2e-08 34.8 5.2 1.2e-08 34.8 3.6 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KII85656.1 - 0.00014 21.5 5.4 0.00014 21.5 3.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KII85656.1 - 0.00018 21.8 2.7 0.00018 21.8 1.9 2.6 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 KII85656.1 - 0.00048 20.4 3.9 0.00048 20.4 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KII85656.1 - 0.002 17.8 3.0 0.0023 17.6 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 KII85656.1 - 0.036 14.3 10.2 5.1 7.4 5.1 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 KII85656.1 - 1 10.0 6.6 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain NMO PF03060.10 KII85657.1 - 1.3e-64 218.4 1.0 1.6e-64 218.1 0.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KII85657.1 - 3.3e-09 36.1 0.0 0.00028 19.9 0.4 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 KII85657.1 - 0.042 12.8 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Ifi-6-16 PF06140.8 KII85657.1 - 0.41 10.4 4.0 0.35 10.6 0.6 2.3 2 0 0 2 2 2 0 Interferon-induced 6-16 family Epimerase PF01370.16 KII85658.1 - 2.7e-21 76.0 0.0 2.7e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII85658.1 - 2.5e-14 52.6 0.0 6.1e-14 51.3 0.0 1.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII85658.1 - 1.6e-13 51.0 0.1 6.9e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII85658.1 - 6.2e-09 35.1 0.0 4.9e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII85658.1 - 0.0015 17.8 0.0 0.0033 16.7 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KII85658.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KII85658.1 - 0.015 15.1 1.2 0.085 12.7 0.9 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KII85659.1 - 3.5e-22 79.0 0.0 5.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII85659.1 - 4.3e-12 45.3 0.0 7.6e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII85659.1 - 4.3e-09 36.6 0.9 1.3e-08 35.1 0.6 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII85659.1 - 1.6e-07 30.4 0.0 7.7e-06 25.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII85659.1 - 0.0016 17.6 0.1 0.0045 16.2 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KII85659.1 - 0.045 13.6 0.7 1.7 8.5 0.5 2.5 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KII85659.1 - 0.048 12.5 0.0 4.4 6.1 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KII85659.1 - 0.15 10.9 0.2 0.3 9.9 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.2 KII85661.1 - 8.9e-09 34.9 0.1 0.0002 21.0 0.0 2.4 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.1 KII85661.1 - 0.24 11.1 1.0 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Leucine rich repeat Phytase-like PF13449.1 KII85662.1 - 2.9e-21 76.0 0.0 5.3e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 KII85662.1 - 0.047 12.6 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 SdiA-regulated Phytase-like PF13449.1 KII85663.1 - 3.9e-21 75.6 2.7 1.1e-20 74.2 1.9 1.8 1 1 0 1 1 1 1 Esterase-like activity of phytase Abhydrolase_5 PF12695.2 KII85664.1 - 6.4e-06 25.9 0.0 9.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KII85664.1 - 0.0004 19.9 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KII85664.1 - 0.00069 19.1 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 KII85664.1 - 0.0032 16.0 0.0 0.4 9.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) COesterase PF00135.23 KII85664.1 - 0.0074 15.0 0.1 0.96 8.0 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KII85664.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII85664.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 KII85664.1 - 0.071 12.3 0.1 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KII85665.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KII85665.1 - 0.00039 19.0 0.0 0.11 10.9 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 KII85665.1 - 0.00059 19.1 0.0 0.0013 17.9 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KII85665.1 - 0.00095 18.6 0.0 0.0023 17.3 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KII85665.1 - 0.0044 16.6 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KII85665.1 - 0.029 13.8 0.1 0.086 12.2 0.1 1.8 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.23 KII85665.1 - 0.056 12.1 0.3 1.9 7.1 0.0 2.5 3 0 0 3 3 3 0 Carboxylesterase family Peptidase_S9 PF00326.16 KII85665.1 - 0.088 12.0 0.0 1 8.5 0.0 2.1 1 1 0 2 2 2 0 Prolyl oligopeptidase family AMP-binding PF00501.23 KII85670.1 - 1.9e-50 171.4 0.0 2.9e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 KII85670.1 - 3.6e-16 57.8 2.1 0.00065 19.0 0.0 8.1 8 0 0 8 8 8 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 KII85670.1 - 1.7e-10 40.9 0.1 4.6e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 KII85670.1 - 1.2e-05 24.7 6.1 0.27 10.8 0.0 5.3 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase zf-C3HC4_2 PF13923.1 KII85670.1 - 0.001 19.0 2.5 0.002 18.1 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII85670.1 - 0.0042 16.7 1.8 0.0074 15.9 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII85670.1 - 0.04 13.5 1.3 0.069 12.8 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85670.1 - 0.095 12.4 1.8 0.19 11.4 1.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII85670.1 - 0.098 12.3 3.6 0.18 11.5 2.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FhuF PF06276.7 KII85670.1 - 0.19 11.7 1.4 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter zf-C3HC4_4 PF15227.1 KII85670.1 - 0.33 10.8 3.5 0.65 9.9 2.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KII85670.1 - 0.64 9.9 2.2 1.6 8.6 1.5 1.8 1 0 0 1 1 1 0 Ring finger domain F-box-like PF12937.2 KII85672.1 - 3.5e-09 36.2 1.7 7.3e-09 35.2 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII85672.1 - 0.057 13.0 3.3 5.4 6.8 0.1 2.6 2 0 0 2 2 2 0 F-box domain Pil1 PF13805.1 KII85674.1 - 1e-10 41.2 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2730 PF10805.3 KII85674.1 - 0.062 13.0 0.9 0.13 11.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) RNA_capsid PF03035.9 KII85675.1 - 7.4 6.2 10.6 17 5.1 7.4 1.6 1 1 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein GIT_SHD PF08518.6 KII85676.1 - 9.4e-14 50.4 0.3 2.5e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Beta-lactamase PF00144.19 KII85679.1 - 3.1e-43 148.0 0.0 4.8e-43 147.4 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase FlgD_ig PF13860.1 KII85680.1 - 0.008 15.8 0.0 0.051 13.3 0.1 2.2 2 1 0 2 2 2 1 FlgD Ig-like domain UBA PF00627.26 KII85680.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain adh_short_C2 PF13561.1 KII85681.1 - 7e-23 81.6 0.0 8.2e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII85681.1 - 1.2e-11 44.7 1.3 1.6e-11 44.4 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase AdoHcyase_NAD PF00670.16 KII85681.1 - 0.0027 17.5 0.9 0.019 14.7 0.6 2.1 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 KII85681.1 - 0.0034 16.4 0.1 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.5 KII85681.1 - 0.0067 16.1 0.1 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII85681.1 - 0.065 13.0 0.8 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KII85682.1 - 2.6e-21 76.4 0.0 3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII85682.1 - 8e-13 48.6 0.2 1e-12 48.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII85682.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KII85682.1 - 0.002 17.1 0.1 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 KII85682.1 - 0.0074 14.9 0.0 0.0097 14.5 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.16 KII85682.1 - 0.029 14.1 0.6 0.057 13.2 0.4 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 KII85682.1 - 0.046 13.1 0.2 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KII85682.1 - 0.11 12.2 2.0 0.23 11.2 1.2 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KII85683.1 - 2e-27 96.4 0.0 2.8e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII85683.1 - 9.5e-08 32.1 0.4 1.3e-07 31.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase PTR2 PF00854.16 KII85684.1 - 4e-44 150.9 11.8 6.9e-43 146.8 8.2 2.4 1 1 0 1 1 1 1 POT family DUF872 PF05915.7 KII85684.1 - 0.23 11.3 2.1 18 5.2 0.3 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Phage_holin_1 PF04531.8 KII85684.1 - 0.69 10.0 2.9 5.5 7.1 0.2 3.0 2 0 0 2 2 2 0 Bacteriophage holin AhpC-TSA PF00578.16 KII85686.1 - 3.6e-28 97.7 0.0 5.3e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII85686.1 - 1.2e-19 70.2 0.0 2.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KII85686.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme TORC_M PF12885.2 KII85686.1 - 0.03 14.1 0.7 0.051 13.3 0.2 1.5 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain HMG14_17 PF01101.13 KII85686.1 - 1.5 9.5 13.9 2.9 8.6 9.6 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 LRR_6 PF13516.1 KII85687.1 - 1.3e-16 58.7 17.9 0.02 14.8 0.3 9.5 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 KII85687.1 - 1.4e-12 46.8 17.7 0.00026 20.5 0.5 7.1 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII85687.1 - 4.2e-09 35.1 8.6 8.3 6.8 0.0 9.4 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.1 KII85687.1 - 1.5e-06 27.8 15.6 0.0015 18.2 2.4 5.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_7 PF13504.1 KII85687.1 - 0.00072 19.3 21.7 10 6.8 0.0 9.0 10 0 0 10 10 10 2 Leucine rich repeat Tn7_Tnp_TnsA_N PF08722.6 KII85687.1 - 0.22 11.5 0.0 0.53 10.2 0.0 1.6 1 0 0 1 1 1 0 TnsA endonuclease N terminal GST_N_3 PF13417.1 KII85690.1 - 4.5e-11 42.8 0.2 9.9e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII85690.1 - 4e-06 26.7 0.1 7.3e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII85690.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII85690.1 - 0.012 15.5 1.3 0.044 13.6 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII85690.1 - 0.045 14.2 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 KII85691.1 - 9.4e-07 28.4 0.0 2.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII85691.1 - 0.0013 18.3 0.1 0.0046 16.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KII85691.1 - 0.047 13.4 0.4 0.16 11.7 0.2 2.0 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 KII85691.1 - 0.15 12.1 0.4 16 5.9 0.0 3.7 2 1 1 3 3 3 0 Leucine Rich Repeat Transaldolase PF00923.14 KII85692.1 - 2.1e-94 315.9 0.0 2.4e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase adh_short_C2 PF13561.1 KII85693.1 - 2.1e-25 89.9 0.0 2.6e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII85693.1 - 3.2e-09 36.9 0.3 8.6e-09 35.5 0.1 1.7 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KII85693.1 - 0.0035 17.3 0.3 0.0049 16.8 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KII85693.1 - 0.0057 15.7 0.1 0.0095 15.0 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 KII85693.1 - 0.032 14.0 1.1 0.12 12.1 0.7 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KII85693.1 - 0.032 14.0 1.3 0.071 12.9 0.9 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2939 PF11159.3 KII85695.1 - 0.0043 17.1 0.1 0.086 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2939) Gp-FAR-1 PF05823.7 KII85695.1 - 0.048 13.6 0.7 0.13 12.1 0.5 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Peptidase_M14 PF00246.19 KII85696.1 - 2.3e-58 198.0 0.0 3.1e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ATG13 PF10033.4 KII85697.1 - 2.8e-41 141.4 0.0 4.1e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Asp PF00026.18 KII85699.1 - 1.1e-76 258.1 11.7 1.3e-76 257.9 8.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KII85699.1 - 6.8e-08 32.2 0.1 5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KII85699.1 - 2.7e-05 24.1 4.3 7.3e-05 22.7 1.2 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.18 KII85700.1 - 4.6e-45 154.2 3.7 2.1e-44 152.0 2.6 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII85700.1 - 0.00089 19.7 2.8 0.077 13.5 0.9 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KII85700.1 - 0.0089 15.5 0.8 0.099 12.1 0.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KII85700.1 - 0.061 13.2 2.9 1.2 9.0 1.1 3.2 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Asp PF00026.18 KII85701.1 - 5.8e-43 147.3 12.4 1.3e-42 146.2 8.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII85701.1 - 1.2e-05 25.3 6.4 3.3e-05 23.8 2.4 3.1 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII85701.1 - 0.0076 16.7 8.8 0.036 14.5 1.1 3.4 4 0 0 4 4 4 2 Aspartyl protease F-box-like PF12937.2 KII85703.1 - 0.017 14.8 0.5 0.045 13.4 0.2 1.9 2 0 0 2 2 2 0 F-box-like Abhydrolase_5 PF12695.2 KII85704.1 - 2.2e-07 30.7 0.1 3.4e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII85704.1 - 0.00063 19.0 1.2 0.0039 16.4 0.2 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KII85704.1 - 0.00074 19.0 0.3 0.0022 17.4 0.2 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KII85704.1 - 0.00078 18.7 0.1 0.0018 17.5 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase COesterase PF00135.23 KII85704.1 - 0.01 14.6 0.0 0.71 8.5 0.0 2.5 3 0 0 3 3 3 0 Carboxylesterase family AXE1 PF05448.7 KII85704.1 - 0.088 11.2 0.0 0.19 10.1 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Dehydrin PF00257.14 KII85705.1 - 0.00019 21.8 29.9 9.5e+03 -3.3 20.7 4.4 1 1 0 1 1 1 0 Dehydrin DUF1024 PF06260.7 KII85705.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Abhydrolase_5 PF12695.2 KII85706.1 - 7.6e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII85706.1 - 4.4e-05 22.8 0.1 0.003 16.7 0.1 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KII85706.1 - 4.8e-05 22.6 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KII85706.1 - 9.5e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 KII85706.1 - 0.00094 17.7 0.1 0.79 8.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 KII85706.1 - 0.033 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family F-box-like PF12937.2 KII85707.1 - 0.0089 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like AF1Q PF15017.1 KII85707.1 - 0.12 12.2 1.9 6 6.8 1.0 2.4 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Bd3614_N PF14442.1 KII85707.1 - 0.66 9.9 4.0 1.7 8.6 2.8 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Sigma70_ner PF04546.8 KII85707.1 - 0.74 9.3 3.4 1.3 8.5 2.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region MFS_1 PF07690.11 KII85708.1 - 1.3e-28 99.7 23.0 4.4e-28 97.9 16.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-C3HC4_3 PF13920.1 KII85713.1 - 9.3e-10 38.0 3.1 1.6e-09 37.2 1.4 3.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII85713.1 - 0.00012 21.9 3.9 0.00012 21.9 2.7 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 KII85713.1 - 0.005 16.7 4.0 0.32 10.8 0.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) zf-RING_5 PF14634.1 KII85713.1 - 2 8.2 17.3 0.053 13.2 2.0 3.3 3 0 0 3 3 3 0 zinc-RING finger domain zf-C2H2 PF00096.21 KII85715.1 - 0.00035 20.7 0.2 0.0014 18.8 0.2 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII85715.1 - 0.00058 20.0 0.4 0.00058 20.0 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 KII85715.1 - 0.072 12.8 0.3 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 KII85715.1 - 0.34 11.0 2.5 0.44 10.7 0.0 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AMP-binding PF00501.23 KII85716.1 - 4.3e-52 176.9 0.0 6.3e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 KII85716.1 - 2.5e-14 52.0 8.8 0.0018 17.7 0.0 7.9 8 0 0 8 8 8 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 KII85716.1 - 2.1e-10 40.7 0.8 6.9e-10 39.0 0.6 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KII85716.1 - 4e-07 30.8 0.3 0.0011 19.8 0.1 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 KII85716.1 - 0.053 13.0 7.5 16 5.1 0.3 5.1 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Aldo_ket_red PF00248.16 KII85717.1 - 6.2e-54 182.7 0.0 7.6e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peroxin-3 PF04882.7 KII85718.1 - 1.6e-95 320.4 0.0 1.9e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Toxin_30 PF08117.6 KII85720.1 - 0.011 15.7 3.1 0.011 15.7 2.1 2.1 2 0 0 2 2 2 0 Ptu family Kdo PF06293.9 KII85721.1 - 3.5e-05 22.9 0.0 6.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII85721.1 - 0.00014 21.7 5.9 0.00023 20.9 3.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KII85721.1 - 0.0033 16.6 0.0 0.0073 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 KII85721.1 - 0.0052 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF3602 PF12223.3 KII85723.1 - 9.5e-14 51.5 32.3 7.8e-05 22.9 3.8 5.4 1 1 4 5 5 5 4 Protein of unknown function (DUF3602) RAP1 PF07218.6 KII85723.1 - 0.32 9.0 1.2 0.63 8.0 0.8 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDE_1 PF03184.14 KII85726.1 - 1.8e-33 115.4 0.0 2.4e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KII85726.1 - 0.00019 21.1 0.9 0.00035 20.3 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 KII85726.1 - 0.001 18.8 0.2 0.011 15.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease ADIP PF11559.3 KII85729.1 - 0.53 10.1 5.5 0.9 9.4 3.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Epimerase PF01370.16 KII85735.1 - 3.2e-19 69.3 0.3 6.7e-19 68.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII85735.1 - 1.4e-12 46.8 0.4 2.5e-12 46.0 0.3 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KII85735.1 - 5.1e-12 45.2 0.6 5.5e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KII85735.1 - 6.2e-08 32.8 2.6 1.8e-07 31.3 1.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII85735.1 - 8.5e-07 29.0 2.7 1.6e-06 28.1 1.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KII85735.1 - 4.3e-05 22.5 0.1 7.7e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KII85735.1 - 0.0014 17.9 0.5 0.002 17.4 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KII85735.1 - 0.0098 15.5 2.3 0.036 13.7 1.6 1.9 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 KII85735.1 - 0.031 13.6 0.3 0.044 13.1 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KII85735.1 - 0.039 13.7 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KII85735.1 - 0.096 13.1 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S28 PF05577.7 KII85736.1 - 2.2e-52 178.1 0.5 6.9e-52 176.4 0.4 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SKN1 PF03935.10 KII85737.1 - 3.5e-184 612.6 5.5 3.9e-184 612.5 3.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box PF00646.28 KII85738.1 - 0.00042 19.9 0.0 0.0013 18.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain MRI PF15325.1 KII85738.1 - 0.24 12.3 4.5 0.57 11.1 0.0 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection RIC3 PF15361.1 KII85739.1 - 0.0019 18.4 0.0 0.0021 18.3 0.0 1.0 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 P_C PF06640.6 KII85739.1 - 0.74 9.7 5.5 0.83 9.6 3.8 1.1 1 0 0 1 1 1 0 P protein C-terminus UAA PF08449.6 KII85740.1 - 1.2e-68 231.2 13.0 1.4e-68 231.0 9.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KII85740.1 - 2.1e-06 27.7 26.3 6.9e-05 22.8 7.0 2.8 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KII85740.1 - 4.8e-05 22.5 0.2 0.00021 20.5 0.2 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 KII85740.1 - 0.00037 20.1 16.0 0.0033 17.0 3.8 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KII85740.1 - 0.0026 17.9 6.5 0.0026 17.9 4.5 2.4 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Nup35_RRM PF05172.8 KII85741.1 - 1e-06 28.4 0.0 9.4e-06 25.3 0.0 2.4 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KII85741.1 - 1.8e-05 24.4 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-ZPR1 PF03367.8 KII85742.1 - 1.5e-99 329.8 0.1 1.3e-49 167.4 0.0 3.0 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 KII85742.1 - 0.016 14.8 0.8 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KII85742.1 - 0.034 14.1 4.0 2.6 8.0 0.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain DZR PF12773.2 KII85742.1 - 0.18 11.6 6.8 0.71 9.7 0.1 3.1 2 1 1 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KII85742.1 - 1.5 8.1 7.3 17 4.7 0.1 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Peptidase_C12 PF01088.16 KII85743.1 - 1.7e-57 194.0 0.0 3.9e-57 192.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RTC4 PF14474.1 KII85748.1 - 3.9e-19 68.8 0.0 4.1e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain ABC_membrane PF00664.18 KII85750.1 - 2.3e-62 210.9 25.5 1.2e-34 120.0 4.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII85750.1 - 1.2e-54 184.3 0.1 1.1e-30 106.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 KII85750.1 - 9.8e-06 25.7 4.1 0.096 12.6 0.2 4.2 2 2 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KII85750.1 - 1e-05 25.4 0.0 0.45 10.4 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase Miro PF08477.8 KII85750.1 - 2e-05 25.0 0.5 0.28 11.6 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KII85750.1 - 3e-05 24.1 0.1 0.27 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KII85750.1 - 0.00036 19.9 0.7 0.25 10.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 KII85750.1 - 0.00087 18.1 0.0 0.55 8.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein DUF258 PF03193.11 KII85750.1 - 0.001 18.2 0.1 0.7 9.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KII85750.1 - 0.0027 17.1 0.1 2.5 7.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KII85750.1 - 0.003 16.4 0.1 0.2 10.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 KII85750.1 - 0.0036 17.6 0.8 0.82 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KII85750.1 - 0.0078 15.4 0.4 11 5.2 0.1 3.5 2 2 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 KII85750.1 - 0.0097 15.4 1.0 0.86 9.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KII85750.1 - 0.011 14.8 0.3 1.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 KII85750.1 - 0.027 14.2 1.9 5 6.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 KII85750.1 - 0.045 13.2 1.4 0.46 9.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KII85750.1 - 0.078 11.8 0.7 5.4 5.7 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.1 KII85750.1 - 0.093 13.5 0.6 29 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KII85750.1 - 0.094 12.3 0.4 0.29 10.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KII85750.1 - 0.16 11.6 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 KII85750.1 - 0.51 10.1 4.4 4.6 6.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 SAD_SRA PF02182.12 KII85751.1 - 2.4e-43 147.1 0.9 2.8e-43 146.9 0.6 1.0 1 0 0 1 1 1 1 SAD/SRA domain SAM_adeno_trans PF01887.11 KII85751.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase SAE2 PF08573.5 KII85752.1 - 2e-18 66.8 0.6 2e-18 66.8 0.4 3.0 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Kinetocho_Slk19 PF12709.2 KII85752.1 - 0.0082 16.1 1.4 6.2 6.9 0.0 3.0 2 0 0 2 2 2 2 Central kinetochore-associated DUF904 PF06005.7 KII85752.1 - 0.18 12.1 9.5 1 9.7 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 KII85752.1 - 0.19 11.6 0.5 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KII85752.1 - 0.41 10.2 7.3 1.6 8.3 0.2 2.3 1 1 1 2 2 2 0 IncA protein LTXXQ PF07813.7 KII85752.1 - 0.69 10.3 6.9 13 6.3 0.2 3.8 3 1 0 3 3 3 0 LTXXQ motif family protein GAS PF13851.1 KII85752.1 - 1.2 8.3 11.7 0.077 12.1 0.6 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 KII85752.1 - 1.2 8.6 12.7 0.87 9.1 1.5 3.0 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KII85752.1 - 1.3 9.3 8.3 15 5.9 1.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 KII85752.1 - 5.6 6.7 12.2 0.49 10.1 0.2 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper MS_channel PF00924.13 KII85753.1 - 2.1e-15 56.6 0.8 3.3e-15 55.9 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KII85753.1 - 5e-06 25.4 0.1 1.3e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KII85753.1 - 5e-05 22.8 0.1 0.00019 21.0 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KII85753.1 - 0.00018 21.6 0.6 0.0017 18.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KII85753.1 - 0.00032 19.9 0.1 0.00086 18.5 0.0 1.7 1 0 0 1 1 1 1 EF hand PBP1_TM PF14812.1 KII85753.1 - 0.006 16.8 1.7 0.006 16.8 1.2 2.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal MMPL PF03176.10 KII85753.1 - 0.012 14.2 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 MMPL family DNA_ligase_A_M PF01068.16 KII85754.1 - 1.8e-22 79.7 0.0 3.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KII85754.1 - 3.3e-15 56.3 0.0 5.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus Rcd1 PF04078.8 KII85755.1 - 1.1e-128 427.5 2.2 1.3e-128 427.3 1.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.8 KII85756.1 - 1.2e-55 188.1 1.4 3e-33 114.7 0.4 2.2 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like HNH_2 PF13391.1 KII85756.1 - 0.091 12.5 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease FA_hydroxylase PF04116.8 KII85759.1 - 1.9e-17 63.6 6.8 1.9e-17 63.6 4.7 2.3 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily TFIIF_alpha PF05793.7 KII85760.1 - 0.047 12.0 8.5 0.061 11.7 5.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 KII85760.1 - 0.047 11.7 6.9 0.059 11.4 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.8 KII85760.1 - 0.15 11.2 3.4 0.2 10.8 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SDA1 PF05285.7 KII85760.1 - 0.37 10.0 11.8 0.45 9.7 8.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KII85760.1 - 1.1 7.1 15.9 1.3 6.8 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 KII85760.1 - 1.7 8.1 12.5 0.23 11.0 5.9 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Nop53 PF07767.6 KII85760.1 - 1.9 7.3 9.2 2.8 6.8 6.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Daxx PF03344.10 KII85760.1 - 3.6 5.9 10.9 4.1 5.7 7.6 1.2 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 KII85760.1 - 9.2 6.2 7.4 6.7 6.6 3.9 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.20 KII85762.1 - 0.00039 19.6 0.0 0.00045 19.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KII85762.1 - 0.028 13.7 0.1 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_L28e PF01778.12 KII85764.1 - 1.2e-31 109.5 2.1 1.2e-31 109.5 1.5 1.8 1 1 1 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KII85764.1 - 4.7e-19 68.3 3.8 8.9e-19 67.4 2.6 1.4 1 0 0 1 1 1 1 Mak16 protein C-terminal region DUF1640 PF07798.6 KII85765.1 - 1e-64 217.8 9.2 1.2e-64 217.6 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) VASP_tetra PF08776.6 KII85765.1 - 0.074 12.3 0.8 0.22 10.8 0.1 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain DUF3166 PF11365.3 KII85765.1 - 0.086 13.3 4.2 0.23 11.9 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) DUF4407 PF14362.1 KII85765.1 - 0.57 9.0 6.7 0.86 8.4 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 KII85765.1 - 1.5 8.7 6.0 0.58 10.0 0.4 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 KII85765.1 - 2.3 7.7 7.6 1.1 8.7 2.5 2.2 1 1 0 2 2 2 0 Septum formation initiator Guanylate_kin PF00625.16 KII85766.1 - 5.7e-66 221.4 0.0 7.6e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 KII85766.1 - 1.2e-08 35.1 0.1 5.9e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KII85766.1 - 6.5e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KII85766.1 - 1.4e-05 25.2 0.0 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KII85766.1 - 0.00027 20.1 0.0 0.00033 19.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KII85766.1 - 0.0011 19.8 0.0 0.0021 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII85766.1 - 0.0013 19.0 0.0 0.0049 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KII85766.1 - 0.0031 17.6 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 KII85766.1 - 0.0059 16.0 0.1 0.016 14.6 0.1 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 KII85766.1 - 0.006 16.4 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KII85766.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 KII85766.1 - 0.0076 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KII85766.1 - 0.008 16.4 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 KII85766.1 - 0.0085 15.8 0.0 0.07 12.8 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 KII85766.1 - 0.0087 15.7 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KII85766.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KII85766.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 KII85766.1 - 0.016 15.4 0.0 0.038 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KII85766.1 - 0.031 13.2 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.1 KII85766.1 - 0.031 14.2 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KII85766.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 KII85766.1 - 0.076 11.7 0.1 0.27 9.9 0.1 1.8 1 1 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 KII85766.1 - 0.084 12.6 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Rad17 PF03215.10 KII85766.1 - 0.16 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Pkinase PF00069.20 KII85767.1 - 4.5e-62 209.5 0.0 6.2e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII85767.1 - 9.8e-35 119.8 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII85767.1 - 4.2e-07 29.2 0.0 8.3e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII85767.1 - 0.00094 18.2 0.1 0.0056 15.7 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII85767.1 - 0.011 15.4 0.2 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII85767.1 - 0.12 11.1 0.1 0.66 8.7 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Mus7 PF09462.5 KII85768.1 - 1.1e-75 255.6 0.0 2.2e-75 254.7 0.0 1.5 2 0 0 2 2 2 1 Mus7/MMS22 family DUF1295 PF06966.7 KII85769.1 - 3.7e-51 173.6 3.2 5.2e-51 173.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KII85769.1 - 2.7e-05 24.2 3.4 2.9e-05 24.0 0.0 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KII85769.1 - 0.00043 20.0 2.6 0.0073 16.0 0.0 2.9 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 KII85769.1 - 0.011 15.9 0.9 0.03 14.5 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Syndecan PF01034.15 KII85769.1 - 0.31 10.7 2.9 12 5.6 0.2 3.2 3 0 0 3 3 3 0 Syndecan domain PH PF00169.24 KII85770.1 - 0.001 19.2 0.1 0.003 17.7 0.1 1.9 1 1 0 1 1 1 1 PH domain Cofilin_ADF PF00241.15 KII85770.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Cation_efflux PF01545.16 KII85771.1 - 4.5e-59 199.8 8.5 4.5e-59 199.8 5.9 2.9 2 1 0 2 2 2 1 Cation efflux family Fungal_trans PF04082.13 KII85772.1 - 4.7e-20 71.5 0.1 9.1e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85772.1 - 1.6e-05 24.7 12.1 2.7e-05 23.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.8 KII85773.1 - 2.9e-29 101.7 1.0 3.9e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain TP_methylase PF00590.15 KII85774.1 - 1.4e-41 142.5 2.5 1.5e-41 142.3 1.1 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KII85774.1 - 2.3e-14 53.5 0.0 8.2e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KII85774.1 - 2.6e-08 33.0 0.2 3.3e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KII85774.1 - 6e-05 21.9 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Fungal_trans PF04082.13 KII85775.1 - 1.4e-16 60.1 0.1 2.9e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII85775.1 - 0.00021 21.1 11.5 0.00038 20.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAP1_N PF04849.8 KII85775.1 - 0.29 10.0 0.0 0.44 9.4 0.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region EBP50_C-term PF09007.6 KII85776.1 - 0.11 12.3 0.1 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 EBP50, C-terminal ECH PF00378.15 KII85778.1 - 1.2e-61 207.9 0.0 1.5e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family IncA PF04156.9 KII85779.1 - 8.4e-06 25.5 8.0 0.0013 18.3 3.9 2.1 2 0 0 2 2 2 2 IncA protein ATG16 PF08614.6 KII85779.1 - 0.00042 20.1 9.7 0.0057 16.5 4.3 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) FH2 PF02181.18 KII85779.1 - 0.001 18.0 3.4 0.67 8.7 2.4 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain Spc7 PF08317.6 KII85779.1 - 0.0021 16.8 5.2 1.4 7.4 0.0 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF2408 PF10303.4 KII85779.1 - 0.0027 17.8 2.5 0.0086 16.1 0.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2408) DUF1395 PF07160.7 KII85779.1 - 0.0042 16.6 0.8 0.057 12.9 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1395) DUF3618 PF12277.3 KII85779.1 - 0.0062 16.5 2.4 0.018 15.0 1.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) OmpH PF03938.9 KII85779.1 - 0.013 15.4 0.7 1.2 9.0 0.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF869 PF05911.6 KII85779.1 - 0.016 13.4 3.5 0.15 10.2 1.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Talin_middle PF09141.5 KII85779.1 - 0.021 14.4 0.9 0.052 13.2 0.6 1.6 1 0 0 1 1 1 0 Talin, middle domain DUF1409 PF07197.7 KII85779.1 - 0.022 14.8 0.5 0.022 14.8 0.4 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1409) Reo_sigmaC PF04582.7 KII85779.1 - 0.033 13.3 1.8 0.17 11.0 1.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Rootletin PF15035.1 KII85779.1 - 0.053 13.4 9.8 0.06 13.3 3.1 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ATG_C PF09333.6 KII85779.1 - 0.057 13.5 0.3 7.5 6.7 0.0 2.8 2 1 1 3 3 3 0 ATG C terminal domain GAT PF03127.9 KII85779.1 - 0.071 13.0 5.0 0.18 11.7 3.5 1.6 1 0 0 1 1 1 0 GAT domain F_actin_bind PF08919.5 KII85779.1 - 0.096 12.3 3.0 0.049 13.3 0.4 1.7 2 0 0 2 2 1 0 F-actin binding Prefoldin PF02996.12 KII85779.1 - 0.1 12.2 6.3 0.17 11.5 1.7 2.5 2 1 0 2 2 2 0 Prefoldin subunit E2R135 PF11570.3 KII85779.1 - 0.15 12.1 8.0 0.42 10.6 0.6 2.3 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Sec8_exocyst PF04048.9 KII85779.1 - 0.18 11.4 1.7 8.7 5.9 0.0 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Acetyltransf_11 PF13720.1 KII85779.1 - 0.26 11.5 1.6 0.66 10.2 0.1 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF972 PF06156.8 KII85779.1 - 0.28 11.5 3.3 14 6.0 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KII85779.1 - 0.28 9.5 2.6 0.14 10.5 0.2 1.5 2 0 0 2 2 2 0 AAA domain Metal_resist PF13801.1 KII85779.1 - 0.35 10.8 14.0 0.13 12.2 1.6 2.7 2 0 0 2 2 2 0 Heavy-metal resistance Uds1 PF15456.1 KII85779.1 - 0.44 10.5 8.4 11 6.0 4.4 2.5 2 1 0 2 2 2 0 Up-regulated During Septation Tropomyosin PF00261.15 KII85779.1 - 0.45 9.5 14.0 0.28 10.2 4.3 2.2 2 0 0 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.2 KII85779.1 - 0.52 10.1 13.5 1.7 8.4 3.9 2.2 2 0 0 2 2 2 0 Tropomyosin like APG6 PF04111.7 KII85779.1 - 0.56 9.2 8.9 0.16 11.0 2.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KII85779.1 - 0.56 10.0 11.2 0.34 10.7 1.5 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HisKA_3 PF07730.8 KII85779.1 - 0.67 10.3 9.3 1.8 8.9 1.1 2.7 2 0 0 2 2 2 0 Histidine kinase ADIP PF11559.3 KII85779.1 - 0.7 9.7 9.5 0.083 12.7 2.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 KII85779.1 - 0.79 7.3 12.7 0.16 9.6 4.0 2.0 2 0 0 2 2 2 0 Myosin tail COG2 PF06148.6 KII85779.1 - 0.82 9.5 6.1 28 4.6 0.0 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.1 KII85779.1 - 1.2 8.5 11.1 1.4 8.3 2.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 KII85779.1 - 1.7 8.2 7.8 5.2 6.7 2.4 2.2 2 0 0 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 KII85779.1 - 1.9 8.2 12.1 2.9 7.6 1.8 2.9 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 KII85779.1 - 1.9 7.3 10.4 0.76 8.6 3.8 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 KII85779.1 - 2.2 5.5 9.2 0.26 8.5 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PilJ PF13675.1 KII85779.1 - 2.5 8.4 8.2 12 6.2 1.3 2.9 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Uso1_p115_C PF04871.8 KII85779.1 - 3 7.7 9.3 0.53 10.2 2.7 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TBPIP PF07106.8 KII85779.1 - 5 6.6 6.4 17 4.8 2.8 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1771 PF08590.5 KII85780.1 - 2.8e-12 46.4 8.5 4.9e-12 45.6 5.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 KII85780.1 - 4.5e-07 29.3 6.8 0.00033 20.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 KII85780.1 - 0.00013 22.0 0.1 0.00031 20.8 0.1 1.6 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.4 KII85780.1 - 0.81 9.2 2.0 17 4.9 0.2 2.3 2 0 0 2 2 2 0 Putative zinc-finger domain Ras PF00071.17 KII85782.1 - 1e-51 174.5 0.0 1.3e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII85782.1 - 1.4e-15 57.8 0.0 1.9e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII85782.1 - 2.4e-07 30.1 0.0 2.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KII85782.1 - 0.00037 19.7 0.0 0.001 18.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KII85782.1 - 0.0043 16.2 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KII85782.1 - 0.0069 16.3 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Skp1_POZ PF03931.10 KII85782.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Clathrin PF00637.15 KII85783.1 - 1.3e-205 673.2 32.9 1.6e-32 112.0 0.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KII85783.1 - 4.2e-31 105.0 3.8 0.00025 21.1 0.0 7.8 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 KII85783.1 - 1.9e-29 101.3 0.1 7.5e-29 99.4 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 KII85783.1 - 3.8e-11 41.7 0.4 1.2e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 KII85783.1 - 0.00065 18.6 9.2 0.7 8.6 0.2 4.3 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.1 KII85783.1 - 0.0025 17.5 12.4 3.9 7.5 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII85783.1 - 0.012 15.5 13.0 1.6 8.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII85783.1 - 0.019 14.5 8.7 14 5.5 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 KII85783.1 - 0.032 14.1 0.7 78 3.5 0.0 5.6 7 0 0 7 7 5 0 PPR repeat TPR_2 PF07719.12 KII85783.1 - 0.33 10.9 15.6 37 4.5 0.3 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 KII85783.1 - 0.49 10.4 7.4 46 4.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII85783.1 - 2.5 8.9 17.5 74 4.4 0.0 9.1 9 1 1 10 10 9 0 Tetratricopeptide repeat PQ-loop PF04193.9 KII85784.1 - 2.2e-14 52.7 1.3 2.2e-14 52.7 0.9 1.6 2 0 0 2 2 2 1 PQ loop repeat SDH_alpha PF03313.10 KII85785.1 - 5e-91 304.6 4.2 8e-91 303.9 2.9 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 KII85785.1 - 3e-55 186.5 0.0 1.4e-54 184.3 0.0 2.1 2 0 0 2 2 2 1 Serine dehydratase beta chain TRI5 PF06330.6 KII85786.1 - 1.2e-19 70.2 0.0 1.6e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KII85786.1 - 0.0034 16.6 0.2 0.0067 15.6 0.0 1.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain SET PF00856.23 KII85787.1 - 0.0066 16.7 0.0 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 SET domain NMO PF03060.10 KII85788.1 - 5.1e-50 170.4 3.9 1.1e-48 166.0 2.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KII85788.1 - 0.00023 20.1 0.0 0.36 9.6 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KII85788.1 - 0.00042 19.2 0.3 0.00092 18.1 0.2 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase LSM PF01423.17 KII85789.1 - 3.7e-15 55.2 0.0 5.3e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain AAA_33 PF13671.1 KII85790.1 - 0.11 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain Ecl1 PF12855.2 KII85791.1 - 0.005 16.0 0.8 0.0093 15.2 0.5 1.5 1 0 0 1 1 1 1 Life-span regulatory factor ARL6IP6 PF15062.1 KII85793.1 - 0.074 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Transposase_21 PF02992.9 KII85794.1 - 0.00012 21.2 0.0 0.00026 20.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 SPATA6 PF14909.1 KII85794.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 RhoGAP PF00620.22 KII85799.1 - 5.5e-40 136.4 0.0 1e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KII85799.1 - 5.7e-13 48.9 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PX PF00787.19 KII85799.1 - 1.4e-08 34.5 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 KII85799.1 - 3.7e-07 30.3 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KII85799.1 - 0.0071 16.3 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain SHR3_chaperone PF08229.6 KII85800.1 - 3.4e-36 124.0 0.1 3.7e-36 123.9 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2910 PF11139.3 KII85800.1 - 0.035 13.2 1.0 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) TRI5 PF06330.6 KII85801.1 - 9.2e-18 64.0 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.6 KII85802.1 - 1.1e-16 60.4 0.0 1.5e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KII85802.1 - 0.094 11.9 0.0 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain TRI5 PF06330.6 KII85803.1 - 1.2e-16 60.3 0.0 1.5e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) CPSase_L_D2 PF02786.12 KII85804.1 - 9.7e-80 266.7 0.1 2.8e-79 265.3 0.1 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KII85804.1 - 4.1e-66 222.1 0.0 7.7e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KII85804.1 - 1.3e-36 125.0 0.0 3.4e-36 123.6 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 KII85804.1 - 5.3e-30 104.8 0.0 1.1e-29 103.7 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 KII85804.1 - 1.7e-28 98.7 0.0 5.8e-28 97.0 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KII85804.1 - 2.8e-18 66.2 0.1 5.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KII85804.1 - 7e-18 64.0 6.7 1.3e-17 63.1 2.7 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KII85804.1 - 1.8e-15 56.5 0.0 3.9e-14 52.1 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KII85804.1 - 2e-12 46.5 9.3 6.9e-06 25.6 0.4 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KII85804.1 - 7.2e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KII85804.1 - 5.1e-08 32.4 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KII85804.1 - 5.9e-08 32.3 1.4 0.008 15.5 0.0 2.6 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 KII85804.1 - 1.5e-06 28.4 2.3 0.032 14.5 0.0 3.1 3 0 0 3 3 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KII85804.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.14 KII85804.1 - 0.00038 20.1 3.5 0.00092 18.8 0.5 3.0 3 1 1 4 4 4 1 Glycine cleavage H-protein RimK PF08443.6 KII85804.1 - 0.0016 17.9 0.0 0.0087 15.5 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.6 KII85804.1 - 0.0029 16.8 0.2 0.0061 15.7 0.2 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KII85804.1 - 0.0031 16.7 0.5 0.23 10.5 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 KII85804.1 - 0.0056 16.3 1.1 0.027 14.1 0.8 2.2 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain GARS_A PF01071.14 KII85804.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain UAA PF08449.6 KII85805.1 - 4.3e-14 52.1 19.3 5.9e-14 51.6 13.4 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KII85805.1 - 4.4e-09 36.1 6.7 4.4e-09 36.1 4.6 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family MFS_1 PF07690.11 KII85806.1 - 1.9e-38 132.1 32.3 1.9e-38 132.1 22.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII85806.1 - 1.5e-14 53.4 9.3 1.5e-14 53.4 6.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KII85807.1 - 5.6e-39 133.8 27.2 5.6e-39 133.8 18.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII85807.1 - 6.1e-18 64.6 5.7 6.1e-18 64.6 3.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter SelP_N PF04592.9 KII85808.1 - 7.9 5.7 9.5 22 4.3 6.6 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TRAUB PF08164.7 KII85809.1 - 1.9e-27 95.1 0.0 4.7e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KII85809.1 - 2.5e-24 85.8 0.5 2.5e-24 85.8 0.4 2.6 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor ORC3_N PF07034.6 KII85810.1 - 4.4e-31 108.0 0.0 9.5e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Velvet PF11754.3 KII85811.1 - 1.1e-26 93.6 0.0 1.6e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Tim17 PF02466.14 KII85812.1 - 9.8e-25 87.0 5.7 1.2e-24 86.7 3.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPR_11 PF13414.1 KII85813.1 - 5.4e-23 80.4 2.8 6.1e-11 41.8 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KII85813.1 - 5e-17 60.7 0.1 2.4e-07 30.0 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII85813.1 - 1.5e-16 58.8 1.5 4.7e-07 29.2 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII85813.1 - 1.1e-14 54.6 2.8 9e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII85813.1 - 1.4e-14 53.8 6.0 3.2e-06 26.9 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KII85813.1 - 1.3e-13 49.9 0.3 0.0042 17.1 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII85813.1 - 1.1e-10 41.6 0.6 0.00014 22.1 0.1 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII85813.1 - 2.8e-10 39.9 3.3 0.0002 21.6 0.0 4.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KII85813.1 - 3.6e-09 35.7 0.4 0.0016 18.1 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII85813.1 - 2e-06 27.1 3.8 0.039 13.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KII85813.1 - 7.3e-06 25.7 7.0 0.25 11.3 0.4 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 KII85813.1 - 1.6e-05 24.1 0.4 2.2e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KII85813.1 - 8.7e-05 22.5 0.3 0.066 13.3 0.1 2.4 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KII85813.1 - 0.00016 21.9 0.1 0.21 12.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII85813.1 - 0.00034 20.3 0.2 0.33 10.8 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KII85813.1 - 0.00053 20.1 2.1 0.15 12.5 0.1 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat Apc5 PF12862.2 KII85813.1 - 0.0016 18.2 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 KII85813.1 - 0.0018 18.3 0.7 0.039 14.0 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 KII85813.1 - 0.0053 16.6 2.7 2.3 8.1 0.1 3.2 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 KII85813.1 - 0.016 15.2 0.4 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat DUF3856 PF12968.2 KII85813.1 - 0.029 14.2 0.6 1.9 8.2 0.4 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) AAA_33 PF13671.1 KII85814.1 - 4.6e-24 84.9 1.4 1e-23 83.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KII85814.1 - 2.2e-07 31.6 0.0 5.3e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII85814.1 - 1.1e-05 25.6 0.0 0.00094 19.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KII85814.1 - 4.4e-05 22.6 0.0 0.00042 19.4 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_29 PF13555.1 KII85814.1 - 0.0039 16.6 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KII85814.1 - 0.02 14.9 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain tRNA_lig_kinase PF08303.6 KII85814.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain UPF0079 PF02367.12 KII85814.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 APS_kinase PF01583.15 KII85814.1 - 0.03 13.9 0.1 0.056 13.0 0.1 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 KII85814.1 - 0.047 13.9 0.0 0.099 12.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.6 KII85814.1 - 0.062 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain KTI12 PF08433.5 KII85814.1 - 0.071 12.2 0.0 1.5 7.9 0.0 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 KII85814.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KII85814.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KII85814.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 KII85814.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_25 PF13481.1 KII85814.1 - 0.14 11.5 0.1 0.91 8.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 KII85814.1 - 0.14 11.7 0.5 14 5.2 0.0 2.2 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein PX PF00787.19 KII85815.1 - 1.3e-21 76.4 0.0 4.1e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KII85815.1 - 2.5e-08 33.4 7.2 0.00019 20.7 0.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KII85815.1 - 0.0038 16.7 0.9 0.0038 16.7 0.6 1.7 2 0 0 2 2 2 1 BAR domain DUF4391 PF14335.1 KII85815.1 - 0.02 14.2 1.8 0.037 13.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) FliD_N PF02465.13 KII85815.1 - 0.059 13.7 0.5 0.53 10.6 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FAM92 PF06730.6 KII85815.1 - 0.095 12.0 1.6 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 FAM92 protein GreA_GreB_N PF03449.10 KII85815.1 - 0.34 10.9 5.7 1.2 9.2 1.1 2.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal IncA PF04156.9 KII85815.1 - 0.45 10.0 3.6 33 4.0 0.0 2.2 2 0 0 2 2 2 0 IncA protein PX PF00787.19 KII85816.1 - 9e-19 67.3 0.1 1.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KII85816.1 - 0.0021 17.3 6.8 0.0094 15.2 0.8 2.1 2 0 0 2 2 2 2 Vps5 C terminal like SpaB_C PF14028.1 KII85816.1 - 0.55 9.7 5.6 0.91 9.0 0.4 2.3 2 0 0 2 2 2 0 SpaB C-terminal domain CYSTM PF12734.2 KII85817.1 - 0.011 15.7 29.0 0.011 15.7 20.1 4.2 2 2 1 3 3 3 0 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 KII85817.1 - 2.2 8.3 28.9 3.2 7.8 20.0 1.2 1 0 0 1 1 1 0 Proline-rich RCR PF12273.3 KII85817.1 - 2.3 8.7 17.4 2.6 8.5 12.1 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Cytochrom_C1 PF02167.10 KII85818.1 - 1.3e-86 289.8 0.0 1.5e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KII85818.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KII85818.1 - 0.011 16.5 0.2 0.024 15.4 0.1 1.9 1 1 0 1 1 1 0 Cytochrome c AAA_12 PF13087.1 KII85819.1 - 5.1e-39 133.7 0.0 1.4e-38 132.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KII85819.1 - 5.3e-39 133.4 0.1 1.1e-13 51.5 0.0 5.4 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KII85819.1 - 3.2e-27 95.6 24.5 6.5e-25 88.0 0.0 6.7 5 2 0 5 5 5 1 AAA domain AAA_19 PF13245.1 KII85819.1 - 3.7e-18 65.0 8.5 1.9e-07 30.6 0.0 5.5 5 0 0 5 5 5 4 Part of AAA domain AAA_17 PF13207.1 KII85819.1 - 1.1e-15 58.5 4.6 0.01 16.6 0.0 6.3 6 0 0 6 6 4 4 AAA domain AAA_22 PF13401.1 KII85819.1 - 2.5e-13 50.3 6.7 0.0059 16.7 0.0 7.8 6 2 0 6 6 6 3 AAA domain AAA_5 PF07728.9 KII85819.1 - 7.3e-12 45.1 1.4 0.082 12.6 0.0 5.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KII85819.1 - 2e-11 43.4 0.1 0.094 11.8 0.0 4.8 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KII85819.1 - 2.1e-10 41.0 3.7 0.03 14.6 0.0 5.6 4 0 0 4 4 4 3 AAA domain Viral_helicase1 PF01443.13 KII85819.1 - 5.3e-10 39.2 0.2 0.62 9.5 0.0 6.1 6 0 0 6 6 6 3 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KII85819.1 - 2.4e-07 30.7 8.4 0.54 10.1 0.0 5.3 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 KII85819.1 - 2.5e-07 30.8 14.2 0.5 10.3 0.0 6.1 5 0 0 5 5 4 3 AAA ATPase domain RNA_helicase PF00910.17 KII85819.1 - 3.5e-07 30.3 0.1 3.8 7.7 0.0 4.7 4 0 0 4 4 4 2 RNA helicase AAA_24 PF13479.1 KII85819.1 - 2.9e-06 27.0 10.0 1.1 8.8 0.1 5.4 5 0 0 5 5 5 3 AAA domain IstB_IS21 PF01695.12 KII85819.1 - 1.8e-05 24.2 6.7 2 7.7 0.0 4.9 5 0 0 5 5 4 2 IstB-like ATP binding protein AAA_25 PF13481.1 KII85819.1 - 5.7e-05 22.6 8.9 0.12 11.7 0.0 5.8 5 1 1 6 6 5 1 AAA domain ResIII PF04851.10 KII85819.1 - 0.0015 18.3 4.7 0.45 10.3 0.0 4.2 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit VirE PF05272.6 KII85819.1 - 0.0028 17.1 0.0 0.0084 15.5 0.0 1.8 1 0 0 1 1 1 1 Virulence-associated protein E KaiC PF06745.8 KII85819.1 - 0.0031 16.6 3.3 3.3 6.7 0.0 4.5 4 0 0 4 4 4 1 KaiC AAA_28 PF13521.1 KII85819.1 - 0.0036 17.2 17.6 0.82 9.6 0.0 6.0 5 0 0 5 5 4 2 AAA domain DUF2075 PF09848.4 KII85819.1 - 0.0091 15.0 0.0 0.0091 15.0 0.0 6.3 6 2 0 6 6 5 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KII85819.1 - 0.02 15.1 5.3 25 5.1 0.0 5.2 5 0 0 5 5 4 0 ABC transporter Torsin PF06309.6 KII85819.1 - 0.027 14.3 0.3 32 4.3 0.0 3.9 4 0 0 4 4 4 0 Torsin NTPase_1 PF03266.10 KII85819.1 - 0.034 13.8 2.4 23 4.6 0.0 4.3 5 0 0 5 5 4 0 NTPase SRP54 PF00448.17 KII85819.1 - 0.23 10.8 5.4 3.2 7.1 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain Guanylate_cyc_2 PF09778.4 KII85819.1 - 0.26 10.4 0.0 13 4.9 0.0 3.0 3 0 0 3 3 3 0 Guanylylate cyclase Adeno_IVa2 PF02456.10 KII85819.1 - 0.38 9.3 0.0 0.76 8.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Aminotran_5 PF00266.14 KII85820.1 - 2.8e-33 115.2 0.0 3.9e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KII85820.1 - 4.1e-06 26.6 0.8 5e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 B12 binding domain SAC3_GANP PF03399.11 KII85821.1 - 3.5e-57 193.2 0.9 6e-57 192.5 0.6 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KII85821.1 - 6.9e-08 32.3 0.1 2.1e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF3365 PF11845.3 KII85821.1 - 0.039 13.7 0.7 0.17 11.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) tRNA_int_endo PF01974.12 KII85822.1 - 9.4e-19 67.0 0.0 1.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KII85822.1 - 0.0017 17.9 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 KII85823.1 - 5.1e-17 61.0 12.1 2.8e-05 23.8 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat HAND PF09110.6 KII85823.1 - 0.27 11.6 7.0 0.5 10.7 4.8 1.4 1 0 0 1 1 1 0 HAND NIR_SIR PF01077.17 KII85824.1 - 1e-50 171.1 0.0 4.7e-45 152.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KII85824.1 - 3.7e-33 112.9 0.0 6.4e-16 57.7 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KII85824.1 - 3.4e-30 104.9 0.0 6.4e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KII85824.1 - 0.017 14.6 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 KII85824.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain Prenyltrans PF00432.16 KII85825.1 - 4.3e-39 131.7 3.7 3.8e-10 39.1 0.2 6.7 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KII85825.1 - 3e-27 95.2 1.5 2.7e-16 59.9 0.0 5.0 2 2 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KII85825.1 - 6e-25 87.3 2.3 5.1e-10 39.3 0.1 6.3 2 2 3 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 KII85825.1 - 8.5e-09 34.9 0.2 0.19 10.8 0.0 5.0 1 1 3 5 5 5 3 Pectic acid lyase Actin PF00022.14 KII85826.1 - 4e-40 137.4 0.0 9.9e-40 136.1 0.0 1.5 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.21 KII85827.1 - 2e-16 59.2 0.0 2.2e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SET PF00856.23 KII85828.1 - 8.4e-05 22.9 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 SET domain CBM_X PF06204.6 KII85830.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain PMM PF03332.8 KII85832.1 - 1.3e-106 355.1 0.4 1.5e-106 354.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KII85832.1 - 7e-05 22.5 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KII85832.1 - 0.097 11.7 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DNA_pol_B PF00136.16 KII85833.1 - 1.2e-146 489.1 0.1 1.9e-146 488.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KII85833.1 - 5.9e-83 278.4 0.0 1.1e-82 277.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KII85833.1 - 3.4e-23 81.4 7.7 8.2e-23 80.2 5.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KII85833.1 - 0.0079 16.0 0.1 0.027 14.2 0.0 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.15 KII85833.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease DNA_pol_B_2 PF03175.8 KII85833.1 - 0.062 11.9 4.5 0.23 10.0 0.1 2.4 3 0 0 3 3 3 0 DNA polymerase type B, organellar and viral C1_1 PF00130.17 KII85833.1 - 5 6.9 6.9 8.3 6.2 2.6 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Leo1 PF04004.8 KII85836.1 - 3.5e-48 163.5 0.4 3.5e-48 163.5 0.2 1.9 2 0 0 2 2 2 1 Leo1-like protein Atx10homo_assoc PF09759.4 KII85837.1 - 9.6e-22 76.6 0.0 2.3e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 KII85837.1 - 0.024 14.8 2.7 0.65 10.3 0.0 3.9 3 2 1 4 4 4 0 HEAT repeats Arm PF00514.18 KII85837.1 - 0.19 11.5 3.1 3.5 7.5 0.0 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Vma12 PF11712.3 KII85838.1 - 5.4e-14 52.0 0.0 7.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase NUDIX PF00293.23 KII85839.1 - 4.9e-13 48.8 0.1 7.6e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain BRAP2 PF07576.7 KII85840.1 - 5.8e-24 83.7 0.0 1.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KII85840.1 - 8.8e-19 67.3 3.3 2e-18 66.2 2.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KII85840.1 - 9.8e-09 34.9 10.1 9.8e-09 34.9 7.0 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII85840.1 - 1.2e-05 24.8 7.7 2.8e-05 23.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII85840.1 - 4.2e-05 23.5 3.3 0.00011 22.2 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KII85840.1 - 0.00015 21.3 7.2 0.00015 21.3 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85840.1 - 0.00035 20.2 6.9 0.00035 20.2 4.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII85840.1 - 0.00043 20.2 9.6 0.00043 20.2 6.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII85840.1 - 0.0082 15.9 3.8 0.016 15.0 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 KII85840.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMCO5 PF14992.1 KII85840.1 - 0.025 13.7 15.2 0.037 13.1 10.5 1.1 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.14 KII85840.1 - 0.073 10.9 8.7 0.098 10.4 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ArfGap PF01412.13 KII85840.1 - 0.081 12.7 0.5 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-RING_UBOX PF13445.1 KII85840.1 - 0.087 12.5 4.6 0.14 11.8 1.8 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KII85840.1 - 0.13 11.8 6.0 0.31 10.6 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_6 PF14259.1 KII85840.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Laminin_II PF06009.7 KII85840.1 - 1.2 8.8 11.0 2.2 8.0 7.6 1.4 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.6 KII85840.1 - 1.4 7.4 12.0 2.3 6.7 8.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Adenylsucc_synt PF00709.16 KII85840.1 - 1.7 7.2 5.4 13 4.2 3.7 2.0 1 1 0 1 1 1 0 Adenylosuccinate synthetase Striatin PF08232.7 KII85840.1 - 1.7 8.9 13.9 2.1 8.6 8.5 1.9 1 1 1 2 2 2 0 Striatin family Mnd1 PF03962.10 KII85840.1 - 2 8.0 11.0 4 7.0 7.6 1.4 1 0 0 1 1 1 0 Mnd1 family DUF1664 PF07889.7 KII85840.1 - 2.2 8.0 6.8 1 9.1 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TerY-C PF15616.1 KII85840.1 - 2.6 7.9 11.1 0.25 11.2 1.5 2.5 2 0 0 2 2 2 0 TerY-C metal binding domain APG6 PF04111.7 KII85840.1 - 4.8 6.1 13.2 8.4 5.3 9.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Cnd2 PF05786.9 KII85841.1 - 5.9e-157 524.2 8.6 8.6e-157 523.7 5.9 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 DNA_pol_B PF00136.16 KII85843.1 - 2.6e-113 379.2 0.0 3.8e-113 378.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KII85843.1 - 6.3e-56 188.7 0.0 1.1e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KII85843.1 - 6.5e-30 104.1 0.0 1.3e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KII85843.1 - 7.4e-17 60.9 4.4 3e-16 58.9 3.1 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Flavin_Reduct PF01613.13 KII85844.1 - 2.2e-33 115.2 0.3 2.7e-33 115.0 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.20 KII85845.1 - 4.5e-17 62.4 0.2 5.9e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII85845.1 - 2.7e-11 43.7 0.0 3.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII85845.1 - 1.9e-09 37.8 0.1 2.8e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII85845.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family BTB PF00651.26 KII85846.1 - 8.8e-08 32.1 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SH3_1 PF00018.23 KII85848.1 - 7.4e-18 63.6 2.0 8.4e-08 31.4 0.1 3.2 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KII85848.1 - 9.1e-13 47.5 3.5 4.3e-06 26.1 0.3 2.9 2 1 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.25 KII85848.1 - 2.7e-11 43.4 0.0 5.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KII85848.1 - 2.9e-11 43.0 0.0 5.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KII85848.1 - 1.7e-10 41.2 0.0 4.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.12 KII85848.1 - 2.3e-10 39.7 0.7 2.5e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KII85848.1 - 0.0082 16.3 4.8 0.58 10.3 0.4 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain TSC22 PF01166.13 KII85848.1 - 0.11 12.4 1.2 0.34 10.8 0.8 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Trs65 PF12735.2 KII85848.1 - 0.16 11.2 2.6 0.35 10.1 1.8 1.5 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF2947 PF11163.3 KII85849.1 - 0.092 12.3 2.0 0.23 11.0 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) AAA PF00004.24 KII85850.1 - 3.4e-42 143.7 0.0 6.1e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII85850.1 - 2.1e-07 31.0 0.0 2e-05 24.6 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KII85850.1 - 4.3e-07 29.7 0.1 5.5e-06 26.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KII85850.1 - 5.5e-06 26.4 0.0 3.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KII85850.1 - 7.9e-06 26.0 0.0 0.00077 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII85850.1 - 1.2e-05 24.5 0.0 2.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KII85850.1 - 2.5e-05 23.9 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KII85850.1 - 0.00094 19.9 0.2 0.003 18.3 0.1 2.1 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 KII85850.1 - 0.0013 17.7 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KII85850.1 - 0.0013 18.6 0.0 0.0034 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KII85850.1 - 0.0023 17.1 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KII85850.1 - 0.0024 17.3 0.1 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KII85850.1 - 0.0036 17.4 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KII85850.1 - 0.005 15.6 0.0 0.0084 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KII85850.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KII85850.1 - 0.0056 15.9 0.3 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein Zeta_toxin PF06414.7 KII85850.1 - 0.006 15.6 1.0 0.011 14.8 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KII85850.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KII85850.1 - 0.011 15.5 0.1 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KII85850.1 - 0.011 16.0 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KII85850.1 - 0.012 14.9 0.3 0.053 12.9 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KII85850.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 KII85850.1 - 0.013 15.4 0.4 0.013 15.4 0.3 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_3 PF07726.6 KII85850.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KII85850.1 - 0.015 14.7 0.0 0.05 13.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 KII85850.1 - 0.029 13.9 0.0 0.21 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 KII85850.1 - 0.029 14.0 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 KII85850.1 - 0.036 12.9 0.0 0.88 8.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KII85850.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KII85850.1 - 0.043 12.9 0.7 0.14 11.2 0.0 2.1 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 KII85850.1 - 0.051 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KII85850.1 - 0.064 13.5 0.4 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KII85850.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 KII85850.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sugar_tr PF00083.19 KII85851.1 - 1.1e-125 419.7 26.7 1.3e-125 419.5 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII85851.1 - 3.7e-25 88.3 55.4 4.3e-22 78.2 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyto_heme_lyase PF01265.12 KII85852.1 - 2.4e-71 240.3 0.0 2.7e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Peptidase_M16 PF00675.15 KII85853.1 - 5.2e-34 117.1 0.8 1.1e-32 112.8 0.1 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KII85853.1 - 1.1e-32 113.1 0.0 1.6e-19 70.2 0.0 3.4 3 0 0 3 3 3 3 Peptidase M16 inactive domain Herpes_gE PF02480.11 KII85854.1 - 0.0024 16.2 0.1 0.0028 15.9 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KII85854.1 - 0.0034 17.0 0.0 0.0043 16.7 0.0 1.1 1 0 0 1 1 1 1 Protocadherin DUF3377 PF11857.3 KII85854.1 - 0.016 14.7 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF1049 PF06305.6 KII85854.1 - 0.02 14.3 1.0 0.038 13.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3487 PF11990.3 KII85854.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF3357 PF11837.3 KII85854.1 - 0.035 13.9 0.4 0.053 13.3 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Herpes_UL45 PF05473.7 KII85854.1 - 0.079 12.3 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 UL45 protein Glutaredoxin PF00462.19 KII85855.1 - 2.6e-17 62.5 0.0 4.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MTHFR PF02219.12 KII85856.1 - 3.8e-106 354.3 0.0 5.5e-106 353.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Carn_acyltransf PF00755.15 KII85857.1 - 2e-137 458.8 0.0 2.3e-137 458.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CNH PF00780.17 KII85858.1 - 9.9e-78 261.3 0.0 1.5e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KII85858.1 - 3.9e-43 146.6 0.6 7e-43 145.8 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 KII85858.1 - 3.5e-35 121.5 0.0 5.4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KII85858.1 - 8.7e-13 47.8 0.2 2e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.1 KII85858.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Polysacc_deac_1 PF01522.16 KII85859.1 - 1.7e-30 105.2 0.0 3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KII85859.1 - 0.0099 14.8 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 HTH_23 PF13384.1 KII85859.1 - 0.18 11.5 0.0 2.5 7.8 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain Sec1 PF00995.18 KII85860.1 - 1.5e-138 462.9 0.0 1.8e-138 462.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Kelch_4 PF13418.1 KII85861.1 - 3e-10 39.7 3.9 0.00027 20.6 0.0 6.0 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 KII85861.1 - 4.7e-08 32.9 5.1 0.23 11.6 0.1 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KII85861.1 - 1e-06 28.6 5.6 0.14 12.3 0.1 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 KII85861.1 - 4.1e-05 23.1 0.4 6.8 6.6 0.0 4.6 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 KII85861.1 - 0.00048 20.0 6.1 9.4 6.3 0.0 6.1 7 0 0 7 7 7 1 Kelch motif Kelch_1 PF01344.20 KII85861.1 - 0.00051 19.5 0.4 2.9 7.5 0.1 4.1 5 0 0 5 5 5 2 Kelch motif TPR_11 PF13414.1 KII85861.1 - 0.0014 18.2 0.3 0.0053 16.3 0.1 2.0 2 0 0 2 2 2 1 TPR repeat zf-MYND PF01753.13 KII85861.1 - 0.029 14.2 13.2 0.084 12.7 9.1 1.8 1 0 0 1 1 1 0 MYND finger TPR_2 PF07719.12 KII85861.1 - 0.11 12.4 0.2 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ELMO_CED12 PF04727.8 KII85862.1 - 5.6e-26 91.0 0.0 9e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KII85862.1 - 6.4e-14 51.9 0.2 1.3e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) RA PF00788.18 KII85862.1 - 0.042 14.3 1.2 0.12 12.9 0.1 2.2 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF4327 PF14217.1 KII85862.1 - 0.073 12.8 3.8 12 5.7 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4327) Acyl-CoA_ox_N PF14749.1 KII85862.1 - 0.098 12.9 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Peptidase_S10 PF00450.17 KII85865.1 - 1.8e-64 218.4 0.0 5.4e-64 216.8 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase GCFC PF07842.7 KII85866.1 - 1.6e-83 280.2 7.7 1.6e-83 280.2 5.4 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KII85866.1 - 1.2e-07 31.4 0.5 2.5e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KII85866.1 - 0.038 13.8 0.2 0.038 13.8 0.1 2.2 3 0 0 3 3 3 0 DExH-box splicing factor binding site WD40 PF00400.27 KII85867.1 - 1.4e-06 27.9 0.0 0.015 15.1 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 KII85868.1 - 0.00012 21.7 0.7 0.0017 18.1 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF202 PF02656.10 KII85869.1 - 7.9e-06 26.0 0.6 5.9e-05 23.2 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF4395 PF14340.1 KII85869.1 - 0.056 13.5 0.6 0.15 12.1 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) SMK-1 PF04802.10 KII85869.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 Glyco_hydro_7 PF00840.15 KII85870.1 - 1.7e-215 715.4 23.0 1.9e-215 715.1 15.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 F-box-like PF12937.2 KII85871.1 - 2.2e-07 30.4 2.1 2.2e-07 30.4 1.4 2.4 2 0 0 2 2 2 1 F-box-like Actin PF00022.14 KII85873.1 - 4e-28 97.9 0.0 1.8e-13 49.7 0.0 3.1 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 KII85873.1 - 8.7e-07 27.8 0.2 1.2e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DnaJ-X PF14308.1 KII85874.1 - 1.1e-55 188.0 0.1 1.1e-55 188.0 0.1 1.6 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KII85874.1 - 1.4e-24 85.5 1.8 4.8e-24 83.8 1.3 2.0 1 0 0 1 1 1 1 DnaJ domain M20_dimer PF07687.9 KII85875.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KII85875.1 - 1.5e-06 27.8 0.1 2.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RCC1 PF00415.13 KII85876.1 - 1.1e-17 63.9 9.3 3.6e-07 30.2 0.1 6.7 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII85876.1 - 1.1e-09 37.6 27.2 0.0041 16.6 0.7 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 KII85876.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII85877.1 - 2.4e-08 33.5 2.2 5.6e-08 32.3 1.5 1.6 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 KII85877.1 - 0.06 13.5 0.8 75 4.2 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 KII85878.1 - 9e-08 31.7 3.4 2.3e-07 30.4 2.3 1.7 1 0 0 1 1 1 1 F-box-like RRS1 PF04939.7 KII85879.1 - 0.07 12.6 0.5 0.083 12.3 0.4 1.1 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) zf-RING_2 PF13639.1 KII85880.1 - 1.6e-06 27.7 9.3 2.9e-06 26.9 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII85880.1 - 4.6e-06 26.1 7.5 9.7e-06 25.1 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85880.1 - 2.1e-05 24.1 5.5 3.6e-05 23.3 3.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII85880.1 - 4.5e-05 23.3 9.5 9.4e-05 22.3 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85880.1 - 0.00014 21.6 7.7 0.00094 19.0 5.6 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KII85880.1 - 0.00044 19.8 5.3 0.0013 18.3 3.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KII85880.1 - 0.0021 17.8 4.5 0.0086 15.8 3.1 1.9 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Tmpp129 PF10272.4 KII85880.1 - 0.0044 15.7 2.8 0.0072 15.0 1.9 1.2 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-RING_UBOX PF13445.1 KII85880.1 - 0.0086 15.7 3.1 0.021 14.5 0.7 2.5 1 1 1 2 2 2 1 RING-type zinc-finger Spc7 PF08317.6 KII85880.1 - 0.013 14.1 3.7 0.021 13.5 2.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 KII85880.1 - 0.015 14.5 7.2 0.028 13.6 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-rbx1 PF12678.2 KII85880.1 - 0.03 14.4 7.2 0.13 12.3 5.0 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 KII85880.1 - 0.045 13.4 3.4 0.093 12.4 2.4 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Lge1 PF11488.3 KII85880.1 - 0.07 13.3 1.7 0.15 12.2 1.2 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 zf-Nse PF11789.3 KII85880.1 - 0.074 12.5 2.4 0.14 11.7 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAS PF13851.1 KII85880.1 - 0.18 10.9 4.7 0.29 10.3 3.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-Apc11 PF12861.2 KII85880.1 - 0.46 10.3 4.5 1.3 8.8 3.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ABC_tran_2 PF12848.2 KII85880.1 - 0.7 9.7 4.9 1.4 8.8 3.4 1.4 1 0 0 1 1 1 0 ABC transporter IncA PF04156.9 KII85880.1 - 1.2 8.6 7.6 1.9 8.0 5.3 1.3 1 0 0 1 1 1 0 IncA protein FANCL_C PF11793.3 KII85880.1 - 1.5 8.8 5.7 3.6 7.6 3.9 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KII85880.1 - 4.7 6.8 7.0 21 4.7 4.8 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain F-box-like PF12937.2 KII85881.1 - 1.7e-08 34.0 3.7 5.8e-08 32.3 2.6 2.0 1 0 0 1 1 1 1 F-box-like FAT PF02259.18 KII85882.1 - 1.7e-121 405.5 3.6 4.4e-121 404.1 2.5 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KII85882.1 - 2e-57 194.3 0.2 3.9e-57 193.4 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KII85882.1 - 1.3e-50 171.5 3.7 4.3e-49 166.5 0.1 4.6 5 1 1 6 6 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KII85882.1 - 5.3e-38 129.1 2.6 1.1e-37 128.0 0.1 3.1 2 1 1 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 KII85882.1 - 2.9e-20 72.3 4.2 4.1e-07 30.1 0.0 9.2 5 2 4 9 9 9 6 HEAT repeats FATC PF02260.15 KII85882.1 - 3.3e-16 58.4 0.5 7.4e-16 57.2 0.3 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KII85882.1 - 4.5e-12 44.9 16.1 0.29 11.3 0.0 10.5 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.1 KII85882.1 - 1.3e-08 35.0 24.9 9.4e-05 22.7 0.1 10.7 14 1 1 15 15 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KII85882.1 - 2.2e-07 31.1 0.0 10 6.5 0.0 7.3 6 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KII85882.1 - 6.4e-07 28.0 4.5 0.26 9.5 0.1 3.8 3 1 1 4 4 4 3 Adaptin N terminal region Tenui_NCP PF04876.7 KII85882.1 - 0.018 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein TPR_19 PF14559.1 KII85882.1 - 0.058 13.7 1.1 1.6 9.1 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII85882.1 - 1.1 10.1 5.2 7.8 7.4 0.1 4.9 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KII85882.1 - 1.1 8.9 5.6 0.24 11.0 0.2 2.7 3 0 0 3 3 2 0 TPR repeat IBR PF01485.16 KII85884.1 - 5.6e-16 58.1 31.9 1.7e-08 34.1 3.2 3.6 3 0 0 3 3 3 2 IBR domain RRM_1 PF00076.17 KII85884.1 - 3.2e-11 42.6 0.0 1.8e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII85884.1 - 5.6e-11 42.2 0.0 0.00024 21.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.1 KII85884.1 - 4.4e-07 29.5 7.2 4.4e-07 29.5 5.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KII85884.1 - 1.1e-05 25.3 8.3 1.1e-05 25.3 5.7 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85884.1 - 1.2e-05 25.0 6.4 1.2e-05 25.0 4.4 4.4 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KII85884.1 - 2.9e-05 23.8 7.9 2.9e-05 23.8 5.5 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KII85884.1 - 5.2e-05 22.8 8.2 5.2e-05 22.8 5.7 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 KII85884.1 - 7.6e-05 22.4 0.0 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 KII85884.1 - 0.0047 16.6 6.7 0.0047 16.6 4.7 3.6 3 1 0 3 3 3 1 zinc-RING finger domain FAD_binding_3 PF01494.14 KII85885.1 - 3.6e-22 78.8 1.2 4.6e-12 45.6 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KII85885.1 - 7.2e-09 35.0 0.1 2e-05 23.6 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KII85885.1 - 1.2e-05 24.3 0.1 0.0056 15.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII85885.1 - 7.9e-05 22.4 0.0 0.00042 20.1 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KII85885.1 - 0.00014 20.6 0.5 0.0019 16.8 0.1 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.12 KII85885.1 - 0.00014 21.0 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KII85885.1 - 0.00019 20.3 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 KII85885.1 - 0.00088 19.6 0.1 0.0038 17.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII85885.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII85885.1 - 0.0045 16.9 0.3 0.014 15.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII85885.1 - 0.0067 16.5 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII85885.1 - 0.031 12.7 0.2 0.055 11.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF3220 PF11516.3 KII85885.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Sec6 PF06046.8 KII85886.1 - 6.9e-153 509.7 6.8 4.7e-152 506.9 3.2 2.0 2 0 0 2 2 2 2 Exocyst complex component Sec6 DUF885 PF05960.6 KII85886.1 - 0.0005 19.3 9.6 0.19 10.8 0.1 2.8 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF885) Vps53_N PF04100.7 KII85886.1 - 0.029 13.1 5.8 0.83 8.3 0.5 2.6 2 0 0 2 2 2 0 Vps53-like, N-terminal FAD_binding_8 PF08022.7 KII85886.1 - 0.12 12.3 0.0 0.43 10.4 0.0 2.0 1 0 0 1 1 1 0 FAD-binding domain CN_hydrolase PF00795.17 KII85887.1 - 8.6e-29 100.2 0.0 1.3e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KII85887.1 - 4e-22 78.2 0.0 1.7e-21 76.2 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KII85887.1 - 0.0097 15.4 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Asparagine synthase Pyridoxal_deC PF00282.14 KII85888.1 - 3.1e-114 381.2 0.0 3.7e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ACC_central PF08326.7 KII85890.1 - 1.3e-211 704.5 0.0 1.6e-211 704.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KII85890.1 - 3.9e-164 546.6 0.0 5e-164 546.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KII85890.1 - 3.8e-49 166.8 0.0 7.2e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KII85890.1 - 7.1e-25 87.2 0.1 1.6e-24 86.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KII85890.1 - 5e-20 71.4 0.0 2e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KII85890.1 - 3.5e-14 52.2 0.0 7.4e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KII85890.1 - 1.1e-10 41.5 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KII85890.1 - 2.2e-08 33.2 0.0 5e-06 25.4 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KII85890.1 - 0.0049 16.7 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KII85890.1 - 0.037 13.4 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DHO_dh PF01180.16 KII85891.1 - 5.6e-95 317.6 0.0 6.7e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KII85891.1 - 0.076 12.2 0.0 7.4 5.7 0.0 2.5 2 0 0 2 2 2 0 PcrB family TMF_DNA_bd PF12329.3 KII85891.1 - 0.13 12.0 2.6 0.58 10.0 1.8 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lipase3_N PF03893.11 KII85892.1 - 0.058 13.2 0.3 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Lipase 3 N-terminal region Dynein_light PF01221.13 KII85894.1 - 3.6e-37 126.2 0.5 3.9e-37 126.1 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 KII85894.1 - 0.064 13.5 0.0 0.074 13.3 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain He_PIG PF05345.7 KII85895.1 - 2.3e-07 30.7 22.1 3.5e-05 23.7 3.2 5.8 6 0 0 6 6 6 3 Putative Ig domain HEAT_EZ PF13513.1 KII85896.1 - 3.3e-19 68.7 21.5 7.3e-07 29.4 0.0 12.5 12 2 2 14 14 14 3 HEAT-like repeat HEAT_2 PF13646.1 KII85896.1 - 2.1e-17 63.1 9.5 3.5e-05 24.0 0.0 7.7 4 1 2 7 7 7 5 HEAT repeats HEAT PF02985.17 KII85896.1 - 3.1e-14 51.7 15.6 0.0035 17.2 0.0 10.0 10 0 0 10 10 10 3 HEAT repeat IBN_N PF03810.14 KII85896.1 - 4.3e-12 45.7 1.7 4.2e-10 39.3 0.1 3.8 4 1 1 5 5 5 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KII85896.1 - 1.6e-05 25.2 0.2 2.8 8.3 0.0 5.8 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KII85896.1 - 0.00021 19.7 1.5 0.2 9.9 0.0 4.3 5 0 0 5 5 5 1 Adaptin N terminal region Cnd1 PF12717.2 KII85896.1 - 0.0037 17.1 0.0 2.5 7.9 0.0 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KII85896.1 - 0.007 15.7 0.3 2.4 7.4 0.0 4.3 5 1 1 6 6 6 1 CLASP N terminal PBP_dimer PF03717.10 KII85896.1 - 0.14 12.2 0.0 7 6.6 0.1 2.4 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF1019 PF06254.6 KII85896.1 - 0.14 12.3 0.3 12 6.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1019) Mito_fiss_reg PF05308.6 KII85900.1 - 0.0073 15.7 0.9 0.0073 15.7 0.6 3.5 2 1 1 3 3 3 1 Mitochondrial fission regulator 4HBT_3 PF13622.1 KII85900.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.7 2 1 0 2 2 2 0 Thioesterase-like superfamily Herpes_DNAp_acc PF04929.7 KII85900.1 - 6.4 5.6 8.1 11 4.8 3.3 2.2 2 0 0 2 2 2 0 Herpes DNA replication accessory factor GPI-anchored PF10342.4 KII85901.1 - 5.3e-08 33.2 0.7 8.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pro-kuma_activ PF09286.6 KII85902.1 - 3e-36 124.5 0.0 2.1e-34 118.5 0.0 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII85902.1 - 2.6e-13 49.7 2.4 3e-13 49.5 0.3 1.8 1 1 1 2 2 2 1 Subtilase family Acetyltransf_10 PF13673.1 KII85903.1 - 0.00081 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII85903.1 - 0.0026 17.8 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII85903.1 - 0.0029 17.5 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HAD_2 PF13419.1 KII85904.1 - 6e-28 98.2 0.3 1.1e-27 97.3 0.2 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII85904.1 - 6.1e-07 29.0 0.2 1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KII85904.1 - 4e-05 24.1 0.1 0.0009 19.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amidase PF01425.16 KII85905.1 - 6e-72 242.8 11.4 3.4e-70 237.1 7.9 2.3 1 1 0 1 1 1 1 Amidase ABM PF03992.11 KII85906.1 - 1.6e-07 31.2 0.0 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ABM PF03992.11 KII85907.1 - 2.6e-08 33.7 0.1 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.8 KII85907.1 - 0.034 14.1 0.1 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 NIPSNAP LRR_8 PF13855.1 KII85908.1 - 5.2e-15 54.9 9.3 1.9e-09 37.1 0.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KII85908.1 - 5.4e-15 54.6 10.2 1.3e-07 31.0 0.8 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII85908.1 - 2.1e-06 26.9 4.8 0.027 14.4 0.1 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KII85908.1 - 0.00024 20.7 5.7 0.34 11.2 0.5 4.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 KII85908.1 - 0.026 14.5 1.0 13 6.2 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.2 KII85909.1 - 1.2e-09 37.7 2.3 1.7e-06 27.6 0.3 2.5 2 0 0 2 2 2 2 F-box-like Metallophos PF00149.23 KII85910.1 - 9e-09 35.0 0.1 1.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII85910.1 - 0.0005 19.9 0.5 0.0012 18.7 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.15 KII85911.1 - 2.6e-12 46.4 0.0 7.6e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 Glyco_hydro_16 PF00722.16 KII85912.1 - 3.6e-33 114.3 0.1 4.9e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AIP3 PF03915.8 KII85913.1 - 1.8e-108 363.1 2.4 2.9e-108 362.5 1.7 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin-6_N PF09177.6 KII85913.1 - 0.0018 18.6 9.1 0.59 10.5 0.9 4.1 2 1 1 3 3 3 2 Syntaxin 6, N-terminal DUF1664 PF07889.7 KII85913.1 - 0.0037 17.0 2.6 0.0037 17.0 1.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KII85913.1 - 0.033 14.0 10.0 1.2 8.8 0.9 4.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.1 KII85913.1 - 0.044 13.6 5.9 0.04 13.8 0.7 3.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Rho_Binding PF08912.6 KII85913.1 - 0.051 13.8 5.9 3.1 8.1 0.1 3.3 2 0 0 2 2 2 0 Rho Binding TBPIP PF07106.8 KII85913.1 - 0.073 12.6 14.8 0.026 14.0 3.9 3.0 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sipho_Gp157 PF05565.6 KII85913.1 - 0.18 11.3 4.6 0.12 11.9 1.3 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 FlgN PF05130.7 KII85913.1 - 0.23 11.7 5.4 2 8.6 0.0 4.1 3 1 1 4 4 4 0 FlgN protein Syntaxin_2 PF14523.1 KII85913.1 - 0.25 11.4 6.3 10 6.1 0.0 4.1 3 1 1 4 4 4 0 Syntaxin-like protein Lectin_N PF03954.9 KII85913.1 - 0.62 9.4 6.2 2.2 7.7 2.3 3.2 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain EMP24_GP25L PF01105.19 KII85913.1 - 1.1 8.9 5.6 0.19 11.4 0.5 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.14 KII85913.1 - 1.2 6.9 2.6 2.3 5.9 1.8 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 KII85913.1 - 1.6 8.6 13.3 3.9 7.4 0.1 4.4 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 KII85913.1 - 1.7 8.9 13.4 3.3 8.0 2.8 4.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BTB PF00651.26 KII85914.1 - 0.00014 21.7 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CorA PF01544.13 KII85915.1 - 6.8e-11 41.7 4.8 3.2e-10 39.5 3.3 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CitMHS PF03600.11 KII85916.1 - 1.1e-12 47.1 15.1 1.2e-11 43.7 9.5 2.4 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.10 KII85916.1 - 2.7e-10 39.7 24.7 3.7e-06 26.1 8.7 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein FAD_binding_3 PF01494.14 KII85917.1 - 7.1e-86 288.4 0.0 1.1e-85 287.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KII85917.1 - 6.9e-32 110.3 0.0 1.1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 KII85917.1 - 1.8e-07 30.3 0.8 4.3e-07 29.1 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KII85917.1 - 6e-07 28.2 0.9 8.8e-07 27.7 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KII85917.1 - 2e-06 27.7 0.1 6.5e-06 26.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII85917.1 - 3.8e-06 26.0 0.8 8.6e-06 24.8 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KII85917.1 - 1.3e-05 24.4 0.1 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KII85917.1 - 4.4e-05 23.4 0.5 0.0001 22.2 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII85917.1 - 7.7e-05 21.7 1.0 0.00013 20.9 0.7 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KII85917.1 - 0.00035 20.1 0.5 0.0012 18.3 0.3 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KII85917.1 - 0.00041 19.3 1.2 0.00073 18.4 0.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII85917.1 - 0.00083 18.5 1.4 0.0016 17.6 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KII85917.1 - 0.0019 17.8 0.4 0.0036 16.9 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KII85917.1 - 0.0021 18.4 0.1 0.004 17.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KII85917.1 - 0.0031 16.9 0.2 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KII85917.1 - 0.0069 16.4 0.5 0.015 15.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KII85917.1 - 0.009 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 KII85917.1 - 0.018 14.7 0.2 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 KII85917.1 - 0.029 14.3 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 KII85917.1 - 0.03 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 KII85917.1 - 0.031 14.0 0.1 0.077 12.8 0.1 1.6 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.1 KII85917.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 KII85917.1 - 0.08 13.2 0.1 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2199 PF09965.4 KII85917.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) SE PF08491.5 KII85917.1 - 0.2 10.4 0.0 1.6 7.5 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Clr2 PF10383.4 KII85918.1 - 0.0015 18.5 0.0 0.026 14.4 0.0 2.8 3 0 0 3 3 3 1 Transcription-silencing protein Clr2 zf-C2H2_3 PF13878.1 KII85918.1 - 0.092 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO MBOAT PF03062.14 KII85919.1 - 2.8e-31 108.8 16.2 2.8e-31 108.8 11.2 2.3 2 2 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KII85919.1 - 2e-05 24.5 4.1 2e-05 24.5 2.8 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family TPR_19 PF14559.1 KII85920.1 - 4.8e-12 46.0 0.1 1.2e-05 25.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII85920.1 - 1.7e-09 38.0 0.0 1.8e-05 25.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII85920.1 - 2.1e-09 37.1 3.5 0.43 11.3 0.1 6.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KII85920.1 - 9.6e-08 31.5 0.6 0.0001 21.8 0.1 2.9 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 KII85920.1 - 9.9e-06 25.1 0.1 0.85 9.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KII85920.1 - 2e-05 24.5 0.2 0.18 11.7 0.9 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII85920.1 - 0.00033 20.9 0.3 1.1 9.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KII85920.1 - 0.00038 20.4 0.9 0.0059 16.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII85920.1 - 0.0013 18.6 0.2 0.36 10.7 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KII85920.1 - 0.0024 17.6 0.2 3.3 7.6 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KII85920.1 - 0.0028 17.7 0.2 0.1 12.7 0.0 2.5 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KII85920.1 - 0.091 12.8 3.1 0.51 10.4 0.1 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat KAR9 PF08580.5 KII85921.1 - 5e-09 35.0 29.5 5e-09 35.0 20.4 4.8 3 1 1 4 4 4 2 Yeast cortical protein KAR9 Med25_NR-box PF11244.3 KII85921.1 - 0.039 14.4 1.1 3.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing BCS1_N PF08740.6 KII85922.1 - 3e-33 114.9 1.8 4.6e-33 114.4 1.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KII85922.1 - 4.3e-15 56.0 0.0 1.3e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KII85922.1 - 0.00095 19.9 0.0 0.0028 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII85922.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KII85922.1 - 0.0084 15.6 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KII85922.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KII85922.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KII85922.1 - 0.019 14.6 0.2 0.074 12.7 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KII85922.1 - 0.033 13.2 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KII85922.1 - 0.041 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KII85922.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 KII85922.1 - 0.046 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 KII85922.1 - 0.047 13.4 0.1 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KII85922.1 - 0.058 12.3 0.0 0.22 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 KII85922.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KII85922.1 - 0.1 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus PAP2 PF01569.16 KII85923.1 - 9.6e-15 54.4 8.9 1.6e-14 53.6 6.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily Polysacc_synt_C PF14667.1 KII85923.1 - 1.3 8.8 7.3 0.14 11.9 1.8 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Pantoate_ligase PF02569.10 KII85924.1 - 1.6e-82 276.4 0.0 3.1e-82 275.4 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Ribonuc_P_40 PF08584.6 KII85925.1 - 1.1e-27 96.7 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Rep-A_N PF04057.7 KII85927.1 - 3.3e-08 33.2 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.4 KII85927.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD VPS9 PF02204.13 KII85928.1 - 2.1e-30 104.7 0.1 3.4e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KII85928.1 - 2.5e-09 36.4 0.0 6.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 KII85928.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif MFS_1 PF07690.11 KII85929.1 - 1.8e-32 112.4 35.7 2.3e-32 112.1 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1119 PF06550.6 KII85930.1 - 0.042 12.9 0.8 0.063 12.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) HMG_CoA_synt_C PF08540.5 KII85933.1 - 1.3e-84 284.0 0.2 2.8e-84 282.9 0.1 1.5 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KII85933.1 - 3.6e-83 277.3 0.0 5.1e-83 276.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KII85933.1 - 0.024 14.3 0.6 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS_Dcarbxylase PF02666.10 KII85933.1 - 0.055 12.7 0.1 0.67 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylserine decarboxylase DUF1752 PF08550.5 KII85934.1 - 5.2e-07 29.1 9.5 9e-07 28.3 6.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.11 KII85937.1 - 2.6e-31 108.6 31.5 2.6e-31 108.6 21.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KII85937.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.9 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF202 PF02656.10 KII85937.1 - 3.9 7.7 10.5 16 5.8 0.0 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF202) BTB PF00651.26 KII85941.1 - 1.7e-06 27.9 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Dynamin_N PF00350.18 KII85944.1 - 2.8e-26 92.3 0.0 7.3e-26 90.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KII85944.1 - 8.6e-20 70.6 0.0 6.9e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KII85944.1 - 4.4e-09 36.1 0.3 1.1e-08 34.8 0.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KII85944.1 - 4.4e-07 29.8 0.0 1.1e-05 25.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KII85944.1 - 0.016 15.6 0.0 0.057 13.9 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KII85944.1 - 0.032 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KII85944.1 - 0.04 14.2 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 KII85944.1 - 0.07 13.0 3.4 0.2 11.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KII85944.1 - 0.079 12.6 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KII85944.1 - 0.99 9.3 9.6 0.21 11.5 0.2 3.7 2 2 1 3 3 3 0 AAA ATPase domain BTB PF00651.26 KII85945.1 - 7e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII85946.1 - 2.6e-09 37.0 0.0 4.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CDP-OH_P_transf PF01066.16 KII85947.1 - 8.1e-20 71.0 4.4 8.1e-20 71.0 3.0 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PACT_coil_coil PF10495.4 KII85948.1 - 1.4e-12 47.3 0.1 4.8e-12 45.6 0.0 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TPR_MLP1_2 PF07926.7 KII85948.1 - 2.9e-05 23.8 26.1 0.00017 21.3 9.2 10.6 4 3 6 11 11 11 2 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 KII85948.1 - 0.00073 19.3 3.5 0.00073 19.3 2.4 9.8 7 1 2 10 10 10 4 Laminin Domain II IncA PF04156.9 KII85948.1 - 0.0025 17.4 13.3 0.0025 17.4 9.2 9.5 3 2 5 8 8 8 2 IncA protein Reo_sigmaC PF04582.7 KII85948.1 - 0.0054 15.9 29.5 1.1 8.4 0.1 7.1 2 2 5 8 8 8 4 Reovirus sigma C capsid protein Ribonucleas_3_2 PF11469.3 KII85948.1 - 0.019 15.1 0.1 0.019 15.1 0.1 2.4 3 0 0 3 3 3 0 Ribonuclease III Pox_A_type_inc PF04508.7 KII85948.1 - 0.024 14.3 0.1 0.024 14.3 0.1 12.2 18 1 1 19 19 19 0 Viral A-type inclusion protein repeat WEMBL PF05701.6 KII85948.1 - 1.4 7.2 134.4 0.0079 14.7 1.9 6.8 2 2 3 5 5 5 0 Weak chloroplast movement under blue light AAA_13 PF13166.1 KII85948.1 - 2 6.7 84.0 0.82 8.0 20.7 5.7 1 1 3 6 6 6 0 AAA domain DEAD PF00270.24 KII85949.1 - 1.4e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII85949.1 - 0.093 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KII85950.1 - 7.6e-10 38.5 0.0 2.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TIR_2 PF13676.1 KII85950.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 TIR domain NmrA PF05368.8 KII85952.1 - 1.5e-44 152.0 0.0 2.3e-44 151.3 0.0 1.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII85952.1 - 5.7e-21 75.3 0.1 6.9e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KII85952.1 - 0.021 15.0 0.4 0.032 14.5 0.3 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KII85952.1 - 0.03 13.0 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII85952.1 - 0.057 12.8 0.1 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KII85952.1 - 0.13 12.2 0.2 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus BTB PF00651.26 KII85953.1 - 5.1e-08 32.8 0.0 9.9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ESCRT-II PF05871.7 KII85954.1 - 8.5e-35 119.6 0.0 1.1e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Glyco_hydro_35 PF01301.14 KII85955.1 - 1.1e-72 245.1 1.0 1.4e-72 244.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KII85955.1 - 3.8e-44 150.2 4.5 6.3e-44 149.5 3.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KII85955.1 - 1.7e-40 137.7 3.2 1.4e-22 80.0 1.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KII85955.1 - 2.5e-16 58.8 0.0 8.1e-16 57.1 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 KII85955.1 - 0.0039 16.4 0.0 0.0085 15.3 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2057 PF09829.4 KII85955.1 - 0.017 14.7 0.1 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF4470 PF14737.1 KII85956.1 - 1.1e-22 79.6 0.0 2.2e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KII85956.1 - 1.8e-11 43.6 13.9 4.7e-11 42.3 9.6 1.8 1 0 0 1 1 1 1 MYND finger PBP1_TM PF14812.1 KII85957.1 - 0.017 15.3 1.7 0.017 15.3 1.2 4.4 2 1 2 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Macoilin PF09726.4 KII85957.1 - 1.7 6.8 19.7 2.5 6.2 13.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Mitofilin PF09731.4 KII85957.1 - 5 5.6 27.0 9.4 4.7 18.7 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-C3HC4_2 PF13923.1 KII85958.1 - 1e-09 38.2 3.7 2.1e-09 37.2 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85958.1 - 2.2e-09 37.0 3.8 4.4e-09 36.0 2.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII85958.1 - 1.8e-07 30.6 3.4 3.5e-07 29.7 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85958.1 - 1.9e-07 30.7 3.3 1.9e-07 30.7 2.3 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII85958.1 - 1.4e-06 27.8 3.1 1.4e-06 27.8 2.2 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII85958.1 - 5.5e-06 26.0 3.1 5.5e-06 26.0 2.1 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KII85958.1 - 6.5e-06 25.7 2.5 1.3e-05 24.7 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KII85958.1 - 5.1e-05 22.9 1.1 0.0001 22.0 0.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein OTT_1508_deam PF14441.1 KII85958.1 - 0.025 14.3 0.7 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase Borrelia_P83 PF05262.6 KII85958.1 - 0.044 12.0 3.1 0.046 11.9 2.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-Nse PF11789.3 KII85958.1 - 0.077 12.5 0.6 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit KfrA_N PF11740.3 KII85958.1 - 0.08 13.3 10.0 0.095 13.1 6.9 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term FYVE PF01363.16 KII85958.1 - 0.2 11.6 2.8 0.8 9.6 2.0 2.2 1 1 0 1 1 1 0 FYVE zinc finger NARP1 PF12569.3 KII85958.1 - 0.41 9.3 7.5 0.49 9.0 5.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4337 PF14235.1 KII85958.1 - 0.53 10.1 6.4 0.72 9.6 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PGBA_C PF15437.1 KII85958.1 - 1 9.5 17.4 3.8 7.7 12.1 1.8 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal ATP-synt_B PF00430.13 KII85958.1 - 5 6.9 13.0 7 6.4 9.0 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Pol_alpha_B_N PF08418.5 KII85960.1 - 0.71 9.3 4.3 1 8.8 3.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-C3HC4_2 PF13923.1 KII85961.1 - 4.2e-09 36.2 9.0 6.9e-09 35.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85961.1 - 4.3e-09 36.0 8.9 7.6e-09 35.2 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII85961.1 - 5.3e-08 32.4 7.5 8.5e-08 31.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85961.1 - 2.2e-07 30.6 9.2 4.1e-07 29.7 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII85961.1 - 7.3e-07 28.7 7.7 1.4e-06 27.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85961.1 - 3.7e-06 26.5 6.9 6.9e-06 25.6 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain IncA PF04156.9 KII85961.1 - 0.00015 21.4 3.5 0.00025 20.6 2.4 1.3 1 0 0 1 1 1 1 IncA protein Laminin_I PF06008.9 KII85961.1 - 0.00048 19.5 1.1 0.00087 18.6 0.8 1.4 1 0 0 1 1 1 1 Laminin Domain I zf-RING_UBOX PF13445.1 KII85961.1 - 0.00092 18.8 6.9 0.002 17.7 4.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Myosin_tail_1 PF01576.14 KII85961.1 - 0.002 15.9 12.7 0.012 13.3 8.8 1.8 1 1 0 1 1 1 1 Myosin tail GAS PF13851.1 KII85961.1 - 0.0044 16.2 6.9 0.29 10.2 2.0 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding CCDC144C PF14915.1 KII85961.1 - 0.0056 15.6 6.2 0.0075 15.2 4.3 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region zf-RING_6 PF14835.1 KII85961.1 - 0.0094 15.7 5.9 0.024 14.4 4.1 1.7 1 1 0 1 1 1 1 zf-RING of BARD1-type protein COG2 PF06148.6 KII85961.1 - 0.016 15.0 1.0 0.079 12.8 0.2 2.0 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF605 PF04652.11 KII85961.1 - 0.019 14.3 17.9 0.024 14.0 12.4 1.2 1 0 0 1 1 1 0 Vta1 like MscS_porin PF12795.2 KII85961.1 - 0.041 13.2 6.5 0.11 11.7 4.5 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2730 PF10805.3 KII85961.1 - 0.075 12.7 2.0 0.17 11.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.2 KII85961.1 - 0.083 12.7 12.5 0.49 10.2 8.7 2.0 1 1 0 1 1 1 0 Tropomyosin like Exonuc_VII_S PF02609.11 KII85961.1 - 0.099 12.4 0.8 0.23 11.2 0.6 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit zf-RING_4 PF14570.1 KII85961.1 - 0.099 12.2 4.8 0.27 10.8 3.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tropomyosin PF00261.15 KII85961.1 - 0.14 11.2 12.3 0.46 9.5 7.4 1.8 1 1 0 1 1 1 0 Tropomyosin Auto_anti-p27 PF06677.7 KII85961.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.0 2 1 1 3 3 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1978 PF09321.5 KII85961.1 - 0.2 11.0 6.1 4 6.8 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) zf-Nse PF11789.3 KII85961.1 - 0.31 10.6 5.7 1.2 8.6 3.9 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Nup54 PF13874.1 KII85961.1 - 0.35 10.5 7.8 14 5.2 5.0 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DZR PF12773.2 KII85961.1 - 0.54 10.1 3.7 1.5 8.6 2.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon OTT_1508_deam PF14441.1 KII85961.1 - 0.57 9.9 3.8 0.28 10.9 0.6 1.9 2 0 0 2 2 2 0 OTT_1508-like deaminase DivIC PF04977.10 KII85961.1 - 0.67 9.4 8.6 0.31 10.5 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator zf-rbx1 PF12678.2 KII85961.1 - 0.74 9.9 4.4 1.8 8.7 3.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DUF3584 PF12128.3 KII85961.1 - 0.84 6.8 9.8 1.1 6.5 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 KII85961.1 - 1.4 6.6 4.4 1.8 6.3 2.0 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Fez1 PF06818.10 KII85961.1 - 2.1 8.3 10.5 3.1 7.7 7.3 1.2 1 0 0 1 1 1 0 Fez1 APG6 PF04111.7 KII85961.1 - 8.6 5.3 8.8 16 4.4 6.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 zf-RING_2 PF13639.1 KII85962.1 - 1.6e-10 40.6 2.9 2.6e-10 39.9 2.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII85962.1 - 2e-09 37.2 2.7 4.1e-09 36.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII85962.1 - 1.6e-08 34.0 1.5 2.9e-08 33.2 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85962.1 - 1.7e-07 31.0 3.5 1.7e-07 31.0 2.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII85962.1 - 2e-07 30.5 2.0 4.8e-07 29.3 1.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85962.1 - 6e-07 29.0 2.2 1.1e-06 28.2 1.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII85962.1 - 1.8e-06 27.5 0.3 3e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger HALZ PF02183.13 KII85962.1 - 1.3e-05 24.7 6.3 0.024 14.3 0.1 4.0 3 1 1 4 4 4 2 Homeobox associated leucine zipper GAS PF13851.1 KII85962.1 - 0.00069 18.8 6.7 0.00069 18.8 4.6 3.1 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 KII85962.1 - 0.0011 18.7 46.0 0.11 12.3 9.5 3.8 1 1 2 3 3 3 2 Tropomyosin like Scaffolding_pro PF11418.3 KII85962.1 - 0.0049 17.1 0.9 0.0049 17.1 0.6 2.0 2 0 0 2 2 2 1 Phi29 scaffolding protein Tropomyosin PF00261.15 KII85962.1 - 0.0057 15.7 52.6 0.022 13.8 24.7 2.8 1 1 1 2 2 2 2 Tropomyosin zf-RING_6 PF14835.1 KII85962.1 - 0.0082 15.9 1.9 0.0082 15.9 1.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 KII85963.1 - 1.4e-07 31.0 7.7 1.4e-07 31.0 5.4 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII85963.1 - 1.6e-07 31.2 10.1 1.6e-07 31.2 7.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII85963.1 - 1.7e-07 30.7 9.5 3.9e-07 29.6 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85963.1 - 8.1e-07 28.7 10.2 1.8e-06 27.7 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KII85963.1 - 8.6e-06 25.3 7.0 2e-05 24.2 4.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Nup54 PF13874.1 KII85963.1 - 0.0001 22.0 0.9 0.0001 22.0 0.6 3.3 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 zf-C3HC4_4 PF15227.1 KII85963.1 - 0.00018 21.3 9.8 0.00042 20.1 6.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING GAS PF13851.1 KII85963.1 - 0.00036 19.7 5.0 0.00036 19.7 3.5 3.0 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KII85963.1 - 0.00075 18.6 10.6 0.00075 18.6 7.4 2.4 1 1 1 2 2 1 1 Autophagy protein Apg6 Laminin_II PF06009.7 KII85963.1 - 0.0019 17.9 1.0 0.0096 15.6 0.0 2.4 1 1 0 2 2 2 1 Laminin Domain II RmuC PF02646.11 KII85963.1 - 0.0032 16.3 8.2 0.046 12.5 0.1 2.9 1 1 2 3 3 3 2 RmuC family MSG PF02349.10 KII85963.1 - 0.0032 17.4 5.3 0.0032 17.4 3.7 1.9 2 0 0 2 2 1 1 Major surface glycoprotein Dor1 PF04124.7 KII85963.1 - 0.013 13.9 0.3 0.03 12.8 0.2 1.6 1 0 0 1 1 1 0 Dor1-like family DUF3450 PF11932.3 KII85963.1 - 0.02 14.1 0.7 0.02 14.1 0.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) zf-RING_4 PF14570.1 KII85963.1 - 0.029 13.9 1.4 0.029 13.9 1.0 2.5 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DUF1664 PF07889.7 KII85963.1 - 0.049 13.4 1.4 1.9 8.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.13 KII85963.1 - 0.065 12.9 16.5 0.24 11.1 0.3 5.3 3 1 3 6 6 5 0 Homeobox associated leucine zipper DHC_N1 PF08385.7 KII85963.1 - 0.07 11.5 1.0 0.1 10.9 0.7 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 zf-RING_UBOX PF13445.1 KII85963.1 - 0.085 12.5 7.9 0.22 11.2 5.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger EzrA PF06160.7 KII85963.1 - 0.13 10.4 11.8 0.0073 14.5 3.6 2.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Sec34 PF04136.10 KII85963.1 - 0.24 11.0 4.6 1.5 8.5 1.6 2.5 1 1 3 4 4 4 0 Sec34-like family DUF4298 PF14131.1 KII85963.1 - 0.3 10.9 9.5 3.1 7.7 1.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) BLOC1_2 PF10046.4 KII85963.1 - 0.38 10.9 8.2 1.3 9.2 0.7 3.5 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UreF PF01730.11 KII85963.1 - 0.41 10.7 7.5 0.99 9.5 5.0 1.9 1 1 0 1 1 1 0 UreF LOH1CR12 PF10158.4 KII85963.1 - 0.48 10.2 2.8 0.7 9.6 0.2 2.2 1 1 1 2 2 2 0 Tumour suppressor protein DUF16 PF01519.11 KII85963.1 - 0.63 10.3 5.8 17 5.6 0.2 3.1 2 2 0 2 2 2 0 Protein of unknown function DUF16 AAA_13 PF13166.1 KII85963.1 - 0.89 7.9 10.3 1 7.7 5.8 1.8 1 1 1 2 2 2 0 AAA domain Vac_Fusion PF02346.11 KII85963.1 - 0.99 8.8 3.6 29 4.1 0.4 2.9 2 1 0 2 2 2 0 Chordopoxvirus fusion protein DUF342 PF03961.8 KII85963.1 - 1.5 7.1 10.7 0.37 9.1 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF479 PF04336.7 KII85963.1 - 1.6 8.9 5.6 17 5.6 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function, DUF479 Tropomyosin_1 PF12718.2 KII85963.1 - 1.8 8.4 35.0 0.36 10.6 7.1 2.5 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 KII85963.1 - 1.9 8.3 13.6 2.3 8.1 0.1 3.7 4 0 0 4 4 3 0 TATA element modulatory factor 1 DNA binding IFT57 PF10498.4 KII85963.1 - 2.7 6.6 11.4 5.7 5.5 7.9 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 FliD_C PF07195.7 KII85963.1 - 2.7 7.2 3.9 6.2 6.0 1.2 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus zf-RING_6 PF14835.1 KII85963.1 - 2.9 7.7 5.6 7.3 6.4 3.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prefoldin_2 PF01920.15 KII85963.1 - 3.4 7.4 19.2 27 4.5 2.9 4.3 4 0 0 4 4 4 0 Prefoldin subunit IncA PF04156.9 KII85963.1 - 3.7 7.1 27.0 5.7 6.4 9.2 3.5 1 1 2 3 3 3 0 IncA protein Mod_r PF07200.8 KII85963.1 - 7.2 6.5 16.0 0.12 12.2 4.1 2.7 1 1 2 3 3 2 0 Modifier of rudimentary (Mod(r)) protein Osmo_CC PF08946.5 KII85963.1 - 7.3 6.7 9.7 7.2 6.7 0.5 3.7 4 1 2 6 6 4 0 Osmosensory transporter coiled coil DUF1910 PF08928.5 KII85963.1 - 8.1 6.5 11.3 12 5.9 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Sporozoite_P67 PF05642.6 KII85963.1 - 8.3 4.1 9.4 12 3.5 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C3HC4_2 PF13923.1 KII85964.1 - 2.9e-10 40.0 9.2 4.4e-10 39.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85964.1 - 1.2e-09 37.8 8.7 1.8e-09 37.2 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII85964.1 - 6.4e-09 35.3 7.4 1.2e-08 34.5 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII85964.1 - 1.9e-08 34.0 9.1 3.1e-08 33.3 6.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII85964.1 - 3.2e-07 29.8 8.4 5.1e-07 29.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85964.1 - 3.7e-06 26.5 7.7 5.8e-06 25.9 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII85964.1 - 0.00012 21.7 7.8 0.00024 20.7 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KII85964.1 - 0.009 15.7 7.2 0.023 14.4 5.0 1.7 1 1 0 1 1 1 1 zf-RING of BARD1-type protein OTT_1508_deam PF14441.1 KII85964.1 - 0.032 14.0 0.6 0.085 12.6 0.4 1.7 1 0 0 1 1 1 0 OTT_1508-like deaminase Tropomyosin PF00261.15 KII85964.1 - 0.034 13.2 13.0 0.072 12.1 9.0 1.4 1 1 0 1 1 1 0 Tropomyosin DUF605 PF04652.11 KII85964.1 - 0.092 12.1 11.4 0.11 11.9 7.9 1.2 1 0 0 1 1 1 0 Vta1 like zf-RING_4 PF14570.1 KII85964.1 - 0.11 12.1 4.4 0.22 11.1 3.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CpXC PF14353.1 KII85964.1 - 0.2 11.6 1.7 0.59 10.0 1.2 1.9 1 1 0 1 1 1 0 CpXC protein Zn_Tnp_IS91 PF14319.1 KII85964.1 - 0.2 11.1 2.1 0.4 10.2 1.5 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-MIZ PF02891.15 KII85964.1 - 0.58 9.7 7.3 0.93 9.0 5.1 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Tropomyosin_1 PF12718.2 KII85964.1 - 0.71 9.7 10.9 0.39 10.5 3.7 2.2 1 1 0 2 2 2 0 Tropomyosin like zf-Nse PF11789.3 KII85964.1 - 0.92 9.0 5.2 1.7 8.2 3.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KII85964.1 - 1.7 8.7 4.8 4 7.6 3.3 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger DUF4463 PF14703.1 KII85964.1 - 2.4 8.7 7.7 11 6.6 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) zf-C3HC4_2 PF13923.1 KII85965.1 - 1.3e-07 31.4 15.0 2.1e-07 30.8 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85965.1 - 4e-06 26.5 15.3 6.5e-06 25.8 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII85965.1 - 1.3e-05 24.8 13.0 2.1e-05 24.0 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85965.1 - 1.8e-05 24.3 13.9 3e-05 23.6 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII85965.1 - 0.00022 21.0 14.1 0.00039 20.2 9.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII85965.1 - 0.0019 17.8 15.8 0.0033 17.0 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3275 PF11679.3 KII85965.1 - 0.0068 16.0 6.0 0.0068 16.0 4.1 2.4 1 1 1 2 2 1 1 Protein of unknown function (DUF3275) zf-RING_UBOX PF13445.1 KII85965.1 - 0.0076 15.9 11.0 0.02 14.6 7.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Laminin_I PF06008.9 KII85965.1 - 0.053 12.8 16.0 0.021 14.1 4.9 2.2 1 1 1 2 2 2 0 Laminin Domain I zf-RING_6 PF14835.1 KII85965.1 - 0.063 13.0 9.1 0.12 12.2 6.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Dor1 PF04124.7 KII85965.1 - 0.083 11.3 4.8 0.11 10.9 2.8 1.6 1 1 0 1 1 1 0 Dor1-like family Transcrip_act PF04949.8 KII85965.1 - 0.085 12.4 8.5 0.059 12.9 4.5 1.7 1 1 1 2 2 2 0 Transcriptional activator DrsE PF02635.10 KII85965.1 - 0.13 12.3 0.3 0.34 10.9 0.2 1.7 1 0 0 1 1 1 0 DsrE/DsrF-like family Tropomyosin PF00261.15 KII85965.1 - 0.33 10.0 22.5 1.6 7.7 15.3 1.9 1 1 0 1 1 1 0 Tropomyosin Spectrin PF00435.16 KII85965.1 - 0.46 10.7 15.0 0.88 9.8 1.1 2.3 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.2 KII85965.1 - 1.6 8.5 22.2 1.2 9.0 5.6 2.2 1 1 0 2 2 2 0 Tropomyosin like DUF4407 PF14362.1 KII85965.1 - 3.1 6.6 10.1 6.3 5.6 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KII85965.1 - 4.7 6.7 15.5 61 3.1 10.8 2.1 1 1 0 1 1 1 0 IncA protein OTT_1508_deam PF14441.1 KII85965.1 - 8.2 6.2 14.7 0.41 10.4 4.1 2.6 2 1 0 2 2 2 0 OTT_1508-like deaminase LMBR1 PF04791.11 KII85965.1 - 9 4.7 10.1 1.6 7.2 3.5 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein GST_N_3 PF13417.1 KII85966.1 - 2.1e-12 47.1 0.4 5.3e-12 45.7 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII85966.1 - 3.6e-08 33.2 0.4 6.3e-08 32.5 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII85966.1 - 0.061 13.2 2.1 0.13 12.1 1.5 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_88 PF07470.8 KII85967.1 - 5.1e-56 190.1 0.8 6.6e-56 189.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 4HBT_3 PF13622.1 KII85967.1 - 0.12 12.1 2.5 0.076 12.7 0.5 1.6 2 0 0 2 2 2 0 Thioesterase-like superfamily NPV_P10 PF05531.7 KII85969.1 - 0.45 10.8 3.8 43 4.4 0.5 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IFT57 PF10498.4 KII85969.1 - 0.7 8.5 14.6 1.3 7.7 10.1 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Filament PF00038.16 KII85969.1 - 0.8 9.1 31.5 0.08 12.4 18.6 1.6 2 1 0 2 2 2 0 Intermediate filament protein DUF4050 PF13259.1 KII85969.1 - 2 8.3 6.0 1.2 9.1 2.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4047 PF13256.1 KII85969.1 - 3 7.8 12.4 0.057 13.3 0.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) Flu_NS2 PF00601.14 KII85969.1 - 6.2 7.0 7.3 2.3 8.5 0.4 2.9 1 1 1 3 3 3 0 Influenza non-structural protein (NS2) DUF948 PF06103.6 KII85969.1 - 7.1 6.5 7.3 3.5 7.5 0.2 3.3 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 KII85969.1 - 7.2 5.1 27.2 0.084 11.5 8.3 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein NMO PF03060.10 KII85970.1 - 1.8e-65 221.2 2.9 2.2e-65 220.9 2.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KII85970.1 - 4.3e-05 22.5 0.1 0.00083 18.3 0.1 2.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.10 KII85970.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FMN_dh PF01070.13 KII85970.1 - 0.045 12.6 2.7 0.068 12.0 1.9 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glyco_hydro_12 PF01670.11 KII85971.1 - 6.9e-29 100.6 0.4 1.3e-28 99.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Tropomyosin PF00261.15 KII85972.1 - 0.013 14.5 6.0 0.017 14.2 4.1 1.0 1 0 0 1 1 1 0 Tropomyosin Atg14 PF10186.4 KII85972.1 - 0.022 13.7 5.7 0.027 13.4 3.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BBP1_C PF15272.1 KII85972.1 - 0.023 14.2 4.1 0.029 13.9 2.8 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ADIP PF11559.3 KII85972.1 - 0.024 14.5 8.7 0.03 14.2 6.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.13 KII85972.1 - 0.059 13.3 0.5 0.09 12.7 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Cortex-I_coil PF09304.5 KII85972.1 - 0.065 13.2 7.2 0.093 12.7 5.0 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil Striatin PF08232.7 KII85972.1 - 0.072 13.4 6.8 0.1 12.9 4.7 1.2 1 0 0 1 1 1 0 Striatin family ERM PF00769.14 KII85972.1 - 0.12 11.8 8.8 0.15 11.5 6.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIVA PF05103.8 KII85972.1 - 0.16 11.9 6.2 0.23 11.5 4.3 1.3 1 0 0 1 1 1 0 DivIVA protein FUSC PF04632.7 KII85972.1 - 0.19 10.0 3.5 0.2 10.0 2.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YlqD PF11068.3 KII85972.1 - 0.29 11.1 5.1 0.36 10.8 3.5 1.1 1 0 0 1 1 1 0 YlqD protein DivIC PF04977.10 KII85972.1 - 0.56 9.7 10.5 0.06 12.8 3.9 1.7 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 KII85972.1 - 0.93 9.8 6.6 0.62 10.3 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) SlyX PF04102.7 KII85972.1 - 1.7 9.0 6.6 2.3 8.6 4.6 1.2 1 0 0 1 1 1 0 SlyX DOR PF14839.1 KII85972.1 - 1.7 8.3 6.3 2 8.1 4.4 1.1 1 0 0 1 1 1 0 DOR family DUF2681 PF10883.3 KII85972.1 - 8.3 6.6 11.5 63 3.8 7.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) zf-C3HC4_3 PF13920.1 KII85974.1 - 5.5e-10 38.7 12.3 9e-10 38.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII85974.1 - 9.7e-10 38.1 15.1 1.7e-09 37.3 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII85974.1 - 1.4e-08 34.6 15.8 2.4e-08 33.8 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII85974.1 - 2.1e-08 33.6 14.7 3.6e-08 32.9 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII85974.1 - 1.4e-07 31.1 13.7 2.2e-07 30.4 9.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII85974.1 - 6e-07 29.2 12.5 1.3e-06 28.2 8.7 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII85974.1 - 2.1e-06 27.3 7.7 6.4e-06 25.7 4.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 KII85974.1 - 0.00084 18.8 7.6 0.0019 17.7 5.3 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KII85974.1 - 0.03 14.1 5.2 0.048 13.5 3.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 KII85974.1 - 0.032 13.4 0.5 0.032 13.4 0.3 1.4 2 0 0 2 2 2 0 Rtf2 RING-finger Baculo_IE-1 PF05290.6 KII85974.1 - 0.093 12.4 7.5 0.15 11.7 5.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 KII85974.1 - 0.45 10.3 9.5 1.2 8.9 6.6 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 KII85974.1 - 0.54 10.1 9.4 1.8 8.4 6.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 KII85974.1 - 0.69 10.0 12.3 3 8.0 8.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger F-box PF00646.28 KII85975.1 - 0.019 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain BTB PF00651.26 KII85977.1 - 3.1e-05 23.9 0.0 8.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_L5_C PF00673.16 KII85978.1 - 3.4e-22 78.0 0.0 4.9e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KII85978.1 - 5.8e-20 70.8 0.1 1.6e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 GPI-anchored PF10342.4 KII85980.1 - 9.6e-09 35.6 4.0 9.6e-09 35.6 2.8 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.4 KII85980.1 - 0.49 8.9 12.5 0.58 8.7 8.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Stanniocalcin PF03298.8 KII85981.1 - 8.8e-07 28.1 0.1 9.5e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family AA_permease_2 PF13520.1 KII85982.1 - 3.9e-54 183.8 47.8 4.6e-54 183.5 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII85982.1 - 1.3e-15 56.7 43.5 1.7e-15 56.3 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2754 PF10953.3 KII85982.1 - 0.14 12.2 0.3 0.14 12.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) COesterase PF00135.23 KII85983.1 - 2.3e-60 204.8 0.0 3.6e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII85983.1 - 7.5e-08 32.1 0.1 3.1e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold MatE PF01554.13 KII85984.1 - 2.7e-41 140.8 25.1 3.3e-28 98.3 5.2 3.0 3 0 0 3 3 3 2 MatE MatE PF01554.13 KII85985.1 - 9e-05 22.1 0.6 0.00012 21.7 0.4 1.1 1 0 0 1 1 1 1 MatE Arginase PF00491.16 KII85986.1 - 2e-82 276.6 0.0 3e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KII85986.1 - 0.088 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 UPF0489 domain AA_permease_2 PF13520.1 KII85987.1 - 3.7e-55 187.1 52.6 4.5e-55 186.9 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII85987.1 - 6.1e-19 67.7 47.8 3.3e-18 65.3 33.0 2.0 1 1 0 1 1 1 1 Amino acid permease Polysacc_deac_1 PF01522.16 KII85988.1 - 1.4e-14 53.7 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KII85988.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) COesterase PF00135.23 KII85989.1 - 1.1e-54 186.1 0.0 1.3e-54 185.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII85989.1 - 1.3e-07 31.4 0.1 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold GDPD PF03009.12 KII85990.1 - 0.061 12.8 0.0 2.6 7.4 0.0 2.3 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family STT3 PF02516.9 KII85991.1 - 2.9e-134 448.6 38.5 8.2e-128 427.3 24.1 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 KII85991.1 - 0.00056 19.8 11.6 0.00056 19.8 8.1 3.8 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ADIP PF11559.3 KII85992.1 - 4.6e-25 88.2 7.1 4.6e-25 88.2 4.9 3.6 3 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KII85992.1 - 0.00022 20.9 7.3 0.00022 20.9 5.0 3.6 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein Cob_adeno_trans PF01923.13 KII85992.1 - 0.068 12.9 0.1 0.068 12.9 0.1 3.7 1 1 3 4 4 4 0 Cobalamin adenosyltransferase Halogen_Hydrol PF10112.4 KII85992.1 - 0.15 11.4 4.3 0.73 9.1 0.0 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Spc42p PF11544.3 KII85992.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.2 4 0 0 4 4 4 0 Spindle pole body component Spc42p WEMBL PF05701.6 KII85992.1 - 0.51 8.7 32.8 1.4 7.2 11.3 2.6 2 1 0 2 2 2 0 Weak chloroplast movement under blue light LPP PF04728.8 KII85992.1 - 0.91 9.3 11.5 2.5 7.9 1.5 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper AIP3 PF03915.8 KII85992.1 - 1.3 7.8 19.7 2 7.2 7.2 2.4 1 1 1 2 2 2 0 Actin interacting protein 3 Filament PF00038.16 KII85992.1 - 3.9 6.8 24.1 1.7 8.0 7.9 3.0 2 2 1 3 3 3 0 Intermediate filament protein UCH PF00443.24 KII85993.1 - 3.6e-72 242.7 0.0 6.5e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII85993.1 - 2.3e-24 86.3 0.0 3.7e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.15 KII85993.1 - 0.0088 15.5 0.7 0.02 14.4 0.5 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-HC5HC2H_2 PF13832.1 KII85994.1 - 2.4e-19 69.3 23.0 1.1e-18 67.2 0.4 4.3 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KII85994.1 - 6.7e-14 51.7 1.2 6.7e-14 51.7 0.9 4.5 3 1 1 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 KII85994.1 - 2.2e-13 50.0 0.0 1.8e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 KII85994.1 - 1e-12 47.5 55.3 1.2e-08 34.4 8.1 5.9 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.1 KII85994.1 - 1.1e-06 27.7 31.9 4.5e-05 22.6 2.5 5.8 5 0 0 5 5 5 2 PHD-finger ELM2 PF01448.19 KII85994.1 - 0.014 16.0 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 ELM2 domain Myb_DNA-binding PF00249.26 KII85994.1 - 0.045 13.8 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1104 PF06518.6 KII85994.1 - 0.092 12.8 0.6 0.54 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) AT_hook PF02178.14 KII85994.1 - 0.098 12.3 5.6 0.43 10.4 3.9 2.2 1 0 0 1 1 1 0 AT hook motif HATPase_c PF02518.21 KII85995.1 - 3.6e-22 78.1 0.0 7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KII85995.1 - 1.9e-14 53.5 0.0 1.1e-13 51.1 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KII85995.1 - 1.5e-06 28.0 0.0 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ISN1 PF06437.6 KII85995.1 - 0.11 11.1 0.2 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Ran_BP1 PF00638.13 KII85996.1 - 1.3e-16 60.7 0.1 2e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain Glycos_transf_2 PF00535.21 KII85997.1 - 2.3e-24 85.9 0.0 2.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KII85997.1 - 4.7e-14 52.7 0.0 1.8e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Toprim_3 PF13362.1 KII85997.1 - 0.046 13.9 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Toprim domain Thi4 PF01946.12 KII85997.1 - 0.066 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family CHGN PF05679.11 KII85997.1 - 0.067 11.9 0.0 0.092 11.4 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Lipase_3 PF01764.20 KII85999.1 - 2.6e-21 75.7 0.0 3.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KII85999.1 - 0.0045 16.2 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KII85999.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII85999.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KII85999.1 - 0.11 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KII86000.1 - 3.9e-22 78.3 0.1 5.4e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KII86000.1 - 0.00046 19.9 0.6 0.00079 19.1 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KII86000.1 - 0.0014 18.1 0.3 0.0023 17.3 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KII86000.1 - 0.014 15.3 0.3 0.031 14.1 0.1 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 KII86000.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 KII86000.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Herpes_UL35 PF04496.7 KII86000.1 - 0.21 11.8 0.9 0.64 10.2 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL35 family zf-MYND PF01753.13 KII86002.1 - 2.5e-08 33.6 11.2 2.5e-08 33.6 7.8 2.3 2 0 0 2 2 2 1 MYND finger Ank_2 PF12796.2 KII86002.1 - 4.5e-08 33.3 0.3 8e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KII86002.1 - 2.7e-07 30.0 0.0 0.0087 15.8 0.2 3.4 3 1 0 3 3 3 2 Ankyrin repeat SEC-C PF02810.10 KII86002.1 - 2.2e-06 27.0 9.2 0.0053 16.2 2.9 2.5 2 0 0 2 2 2 2 SEC-C motif Ank_5 PF13857.1 KII86002.1 - 2.4e-06 27.5 1.2 0.059 13.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII86002.1 - 9.4e-05 22.3 4.4 0.019 15.1 0.2 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 KII86002.1 - 0.081 13.4 1.0 3.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ran_BP1 PF00638.13 KII86003.1 - 2.8e-05 24.1 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Thioredoxin PF00085.15 KII86004.1 - 2.3e-20 72.1 0.0 6e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KII86004.1 - 0.00026 21.1 0.1 0.0014 18.8 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII86004.1 - 0.0096 16.0 0.0 1.7 8.8 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KII86004.1 - 0.034 14.1 1.7 0.038 14.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Lin-8 PF03353.10 KII86004.1 - 7.1 5.8 7.9 10 5.2 5.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ank PF00023.25 KII86005.1 - 8.5e-10 37.9 0.5 0.0042 16.8 0.1 3.4 3 1 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.13 KII86005.1 - 4.5e-09 36.0 9.4 4.5e-09 36.0 6.5 2.0 2 0 0 2 2 2 1 MYND finger Ank_2 PF12796.2 KII86005.1 - 7.3e-09 35.8 0.0 2.5e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KII86005.1 - 1e-05 25.2 1.8 0.016 15.3 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat SEC-C PF02810.10 KII86005.1 - 0.00042 19.7 11.5 0.0012 18.2 3.2 2.7 2 0 0 2 2 2 2 SEC-C motif Ank_4 PF13637.1 KII86005.1 - 0.0011 19.4 1.2 0.14 12.6 0.2 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII86005.1 - 0.048 13.9 0.2 20 5.5 0.1 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf-MYND PF01753.13 KII86006.1 - 2.5e-07 30.4 10.1 2.5e-07 30.4 7.0 2.1 2 0 0 2 2 2 1 MYND finger SEC-C PF02810.10 KII86006.1 - 1.8e-05 24.1 10.9 0.0067 15.9 4.2 2.5 2 0 0 2 2 2 2 SEC-C motif Ank_2 PF12796.2 KII86006.1 - 3.1e-05 24.2 0.7 9.1e-05 22.7 0.5 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KII86006.1 - 0.00037 20.4 0.3 0.037 14.2 0.1 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KII86006.1 - 0.00071 19.2 1.7 0.085 12.7 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KII86006.1 - 0.012 15.8 1.3 0.56 10.5 0.1 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 KII86006.1 - 0.051 14.1 0.3 1.9 9.0 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF605 PF04652.11 KII86007.1 - 2.7 7.2 30.7 3.5 6.9 21.3 1.1 1 0 0 1 1 1 0 Vta1 like Rxt3 PF08642.5 KII86008.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 Pkinase PF00069.20 KII86009.1 - 7.2e-63 212.1 0.0 1.2e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86009.1 - 8.8e-38 129.8 0.0 2.1e-36 125.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII86009.1 - 6.8e-06 25.2 0.3 2.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII86009.1 - 0.052 13.2 0.1 0.052 13.2 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII86009.1 - 0.3 9.8 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Atg14 PF10186.4 KII86009.1 - 2.1 7.2 11.8 3.3 6.5 8.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1319 PF07028.6 KII86009.1 - 3.3 7.9 10.9 1.9 8.6 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) FUSC PF04632.7 KII86009.1 - 9.5 4.5 15.4 17 3.6 10.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNase_H2_suC PF08615.6 KII86010.1 - 2.6e-21 75.9 0.0 3.4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ank PF00023.25 KII86011.1 - 2.6e-11 42.7 0.0 0.00061 19.4 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KII86011.1 - 7.9e-10 38.9 0.0 1.9e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) zf-MYND PF01753.13 KII86011.1 - 3.8e-09 36.2 10.0 1.1e-08 34.8 6.9 1.8 1 0 0 1 1 1 1 MYND finger Ank_3 PF13606.1 KII86011.1 - 2e-07 30.5 1.6 0.002 18.2 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 KII86011.1 - 5.7e-05 23.2 0.2 0.074 13.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) SEC-C PF02810.10 KII86011.1 - 7e-05 22.2 16.0 0.0005 19.5 2.0 2.8 3 0 0 3 3 3 2 SEC-C motif Ank_4 PF13637.1 KII86011.1 - 0.029 14.9 0.2 0.42 11.1 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) zf-MYND PF01753.13 KII86013.1 - 7.3e-08 32.1 9.0 1.2e-07 31.4 6.2 1.3 1 0 0 1 1 1 1 MYND finger DUF2523 PF10734.4 KII86013.1 - 0.02 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) SEC-C PF02810.10 KII86014.1 - 5.3e-09 35.4 3.5 1.4e-05 24.4 1.4 2.6 2 0 0 2 2 2 2 SEC-C motif Ank_2 PF12796.2 KII86014.1 - 1e-08 35.4 0.0 6.2e-08 32.8 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) zf-MYND PF01753.13 KII86014.1 - 1.5e-08 34.3 8.2 3.8e-08 33.0 5.7 1.7 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.1 KII86014.1 - 9e-05 22.5 0.6 0.029 14.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KII86014.1 - 0.00022 20.8 0.4 4 7.4 0.2 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KII86014.1 - 0.0026 17.8 0.1 1.8 9.0 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KII86014.1 - 0.11 13.0 0.2 4.7 7.8 0.1 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SH3_9 PF14604.1 KII86015.1 - 3.1e-30 103.5 1.5 1.7e-15 56.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KII86015.1 - 2.8e-26 90.6 2.3 1.6e-12 46.6 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KII86015.1 - 1.2e-17 63.1 0.0 9.4e-09 34.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KII86015.1 - 6.1e-14 51.9 0.0 8.8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ytp1 PF10355.4 KII86016.1 - 4.8e-68 229.3 10.9 4.8e-68 229.3 7.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KII86016.1 - 8.3e-29 99.2 1.8 8.3e-29 99.2 1.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) PIRT PF15099.1 KII86016.1 - 0.088 12.0 0.1 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4225 PF13988.1 KII86016.1 - 0.33 10.3 0.1 0.33 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) zf-C2H2_4 PF13894.1 KII86017.1 - 1e-05 25.4 11.8 0.08 13.3 1.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KII86017.1 - 1.9 8.9 10.6 1.4 9.4 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Nop14 PF04147.7 KII86017.1 - 9.8 3.9 9.2 13 3.5 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family KH_1 PF00013.24 KII86018.1 - 1.2e-06 28.0 0.0 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KII86018.1 - 0.00024 20.6 0.2 0.0018 17.8 0.1 2.3 2 0 0 2 2 2 1 KH domain Mito_fiss_reg PF05308.6 KII86018.1 - 9.6 5.4 6.6 23 4.2 4.6 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box PF00646.28 KII86019.1 - 2.6e-06 26.9 1.0 2.6e-06 26.9 0.7 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII86019.1 - 0.003 17.2 0.5 0.0056 16.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like UBX PF00789.15 KII86020.1 - 1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain Ima1_N PF09779.4 KII86020.1 - 0.024 15.1 0.1 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Ima1 N-terminal domain UBA PF00627.26 KII86020.1 - 0.031 14.1 0.0 0.34 10.8 0.0 2.9 3 0 0 3 3 3 0 UBA/TS-N domain zf-C2H2_2 PF12756.2 KII86020.1 - 0.047 13.7 0.4 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2296 PF10058.4 KII86020.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C2H2 PF00096.21 KII86020.1 - 0.16 12.3 0.2 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Orbi_VP5 PF00901.12 KII86020.1 - 0.68 8.0 11.3 0.93 7.6 7.8 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 SOBP PF15279.1 KII86020.1 - 2.1 8.6 4.3 2.8 8.2 3.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Atg14 PF10186.4 KII86020.1 - 2.1 7.1 9.8 3 6.7 6.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_M55 PF04951.8 KII86020.1 - 9.9 5.2 9.2 18 4.4 6.4 1.4 1 0 0 1 1 1 0 D-aminopeptidase NAD_binding_10 PF13460.1 KII86021.1 - 5e-10 39.6 0.5 7.1e-10 39.1 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII86021.1 - 0.00023 20.6 0.1 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KII86021.1 - 0.00079 19.7 0.1 0.0023 18.2 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KII86021.1 - 0.00087 18.6 1.1 0.0021 17.3 0.8 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KII86021.1 - 0.043 12.7 0.4 1.8 7.4 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 KII86021.1 - 0.083 12.8 0.1 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SKG6 PF08693.5 KII86022.1 - 0.00082 18.6 0.8 0.0016 17.7 0.1 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF347 PF03988.7 KII86022.1 - 0.01 15.6 0.1 0.034 14.0 0.1 1.9 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Mid2 PF04478.7 KII86022.1 - 0.075 12.4 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor NAD_binding_10 PF13460.1 KII86026.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII86026.1 - 4.6e-07 29.5 0.1 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KII86026.1 - 0.005 17.1 0.3 0.012 15.8 0.1 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KII86026.1 - 0.026 13.7 0.1 0.052 12.8 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family HIM1 PF08732.5 KII86026.1 - 0.052 12.0 0.0 0.15 10.4 0.0 1.5 1 1 0 2 2 2 0 HIM1 NAD_binding_4 PF07993.7 KII86026.1 - 0.055 12.3 0.1 1.4 7.8 0.0 2.5 2 1 1 3 3 3 0 Male sterility protein SseC PF04888.7 KII86027.1 - 0.011 15.1 10.9 0.013 14.8 7.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Mito_carr PF00153.22 KII86027.1 - 0.024 14.3 1.6 5.3 6.8 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial carrier protein Phos_pyr_kin PF08543.7 KII86029.1 - 1.8e-11 43.7 0.0 2.8e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KII86029.1 - 4.5e-08 32.5 0.1 9.7e-07 28.1 0.1 2.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Actin PF00022.14 KII86030.1 - 9.9e-122 406.1 0.0 1.2e-121 405.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KII86030.1 - 0.00037 19.2 0.0 0.00056 18.6 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein START PF01852.14 KII86031.1 - 1.9e-13 50.2 0.0 5.3e-08 32.4 0.0 3.0 3 0 0 3 3 3 2 START domain LisH PF08513.6 KII86032.1 - 0.0004 20.0 0.1 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 LisH EphA2_TM PF14575.1 KII86033.1 - 0.027 14.8 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KII86033.1 - 0.028 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain DUF1183 PF06682.7 KII86033.1 - 0.08 12.5 0.2 0.08 12.5 0.1 2.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1183) DUF4307 PF14155.1 KII86033.1 - 0.17 11.6 1.9 0.28 10.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4307) SKG6 PF08693.5 KII86033.1 - 1 8.7 17.2 0.02 14.2 6.0 2.7 2 1 0 2 2 2 0 Transmembrane alpha-helix domain 3Beta_HSD PF01073.14 KII86034.1 - 6.4e-31 107.0 0.0 4.7e-30 104.2 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII86034.1 - 2e-17 63.4 0.0 3.1e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KII86034.1 - 1.1e-14 54.0 0.0 8.1e-13 47.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KII86034.1 - 1.7e-05 24.7 0.0 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII86034.1 - 0.00013 21.6 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII86034.1 - 0.00021 21.3 0.0 0.0036 17.3 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KII86034.1 - 0.0024 16.8 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KII86034.1 - 0.0052 15.7 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 KII86034.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HSF_DNA-bind PF00447.12 KII86035.1 - 7.7e-32 109.5 0.2 1e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4606 PF15379.1 KII86035.1 - 0.032 14.3 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) NdhO PF11910.3 KII86036.1 - 0.066 12.8 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Spectrin PF00435.16 KII86036.1 - 0.076 13.3 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Spectrin repeat Mt_ATP-synt_B PF05405.9 KII86037.1 - 1.5e-43 148.1 8.0 1.8e-43 147.8 5.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 KII86037.1 - 0.0065 16.3 1.0 0.86 9.4 0.2 2.6 1 1 1 3 3 3 2 Domain of Unknown Function (DUF1539) Apo-CIII PF05778.7 KII86037.1 - 0.083 12.2 1.1 0.99 8.8 0.1 2.8 2 1 1 3 3 3 0 Apolipoprotein CIII (Apo-CIII) Synthase_beta PF11421.3 KII86037.1 - 4.5 7.9 5.9 9.5 6.9 4.1 1.5 1 0 0 1 1 1 0 ATP synthase F1 beta subunit Dynamin_M PF01031.15 KII86038.1 - 4.9e-111 370.2 0.0 7.9e-111 369.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KII86038.1 - 1.1e-54 184.8 0.0 2.3e-54 183.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KII86038.1 - 2.1e-29 101.2 1.0 8.4e-29 99.3 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KII86038.1 - 0.0065 16.4 0.0 0.03 14.2 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KII86038.1 - 0.0092 15.9 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.11 KII86038.1 - 0.045 12.8 0.1 6.2 5.8 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 KII86038.1 - 0.057 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein BCS1_N PF08740.6 KII86040.1 - 7.8e-29 100.6 0.8 7.8e-29 100.6 0.5 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KII86040.1 - 3.2e-14 53.2 0.0 3.3e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KII86040.1 - 0.0006 19.7 0.5 0.0017 18.2 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII86040.1 - 0.0012 18.8 1.4 0.002 18.1 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KII86040.1 - 0.0032 18.2 4.5 0.0066 17.2 0.0 3.0 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 KII86040.1 - 0.0042 16.6 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Macoilin PF09726.4 KII86040.1 - 0.0046 15.3 0.8 0.0079 14.5 0.6 1.3 1 0 0 1 1 1 1 Transmembrane protein KaiC PF06745.8 KII86040.1 - 0.049 12.7 0.0 0.33 10.0 0.0 2.2 3 0 0 3 3 3 0 KaiC DUF815 PF05673.8 KII86040.1 - 0.062 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 KII86040.1 - 0.077 12.6 0.1 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 KII86040.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KII86040.1 - 0.13 12.0 0.1 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KII86040.1 - 0.13 12.3 0.1 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KII86040.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KII86040.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.7 3 0 0 3 3 3 0 AAA domain CAF-1_p150 PF11600.3 KII86040.1 - 0.33 10.2 19.5 0.66 9.3 13.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_11 PF13086.1 KII86040.1 - 0.35 10.3 5.5 3.1 7.2 3.8 2.0 1 1 0 1 1 1 0 AAA domain UPF0172 PF03665.8 KII86040.1 - 0.42 10.0 2.7 0.34 10.3 0.9 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) SR-25 PF10500.4 KII86040.1 - 4.4 6.7 17.4 2.4 7.5 0.6 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SYS1 PF09801.4 KII86042.1 - 2.9e-26 92.2 1.4 4e-18 65.7 0.7 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DPPIV_N PF00930.16 KII86043.1 - 4.9e-94 314.8 0.1 6.5e-94 314.4 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KII86043.1 - 1.1e-47 162.0 1.0 2e-47 161.1 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII86043.1 - 2.2e-08 34.0 0.1 4.4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KII86043.1 - 9.9e-07 28.4 2.3 5.5e-06 26.0 1.6 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KII86043.1 - 4.5e-06 26.6 0.2 8e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KII86043.1 - 0.025 13.0 0.1 0.49 8.8 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KII86043.1 - 0.071 12.5 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PD40 PF07676.7 KII86043.1 - 0.079 12.6 0.9 21 4.9 0.1 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nro1 PF12753.2 KII86044.1 - 2.9e-06 26.5 0.7 0.073 12.0 0.0 3.1 2 2 0 2 2 2 2 Nuclear pore complex subunit Nro1 Mito_carr PF00153.22 KII86045.1 - 5e-58 192.8 4.9 2.8e-21 75.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.13 KII86046.1 - 2.2e-10 40.2 0.0 2.1e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.23 KII86049.1 - 1.2e-27 96.3 0.0 3.6e-27 94.8 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme TPR_11 PF13414.1 KII86051.1 - 7.9e-44 147.1 7.8 2.8e-18 65.3 0.6 5.4 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 KII86051.1 - 2.9e-28 96.2 0.0 7.1e-05 22.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KII86051.1 - 1.3e-26 90.2 0.5 5.8e-05 22.6 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.26 KII86051.1 - 2.2e-21 75.3 0.2 4.4e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 KII86051.1 - 4.3e-19 68.6 13.5 9.5e-05 22.9 1.3 5.6 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.1 KII86051.1 - 4.4e-17 61.6 11.1 1.3e-05 24.9 0.0 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KII86051.1 - 1.6e-14 53.5 8.6 0.00027 20.8 0.0 5.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KII86051.1 - 9.3e-14 50.7 16.0 0.015 15.8 0.0 6.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KII86051.1 - 7.8e-11 42.1 10.1 0.0022 18.3 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KII86051.1 - 1.5e-07 31.0 0.7 0.33 11.2 0.0 6.3 7 1 1 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KII86051.1 - 9.9e-07 28.8 0.0 0.082 13.0 0.1 4.0 2 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KII86051.1 - 8.3e-06 25.0 2.0 0.026 13.6 0.1 4.2 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII86051.1 - 1.9e-05 24.0 1.6 0.26 11.2 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KII86051.1 - 0.00011 21.9 0.8 0.079 12.8 0.1 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KII86051.1 - 0.00014 22.0 0.7 4.9 7.8 0.0 5.0 6 1 0 6 6 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KII86051.1 - 0.00069 18.8 0.3 4.8 6.4 0.0 4.2 4 0 0 4 4 4 1 SHNi-TPR TPR_8 PF13181.1 KII86051.1 - 0.0016 18.0 0.0 80 3.3 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KII86051.1 - 0.0044 16.2 0.2 0.45 9.6 0.0 3.0 4 0 0 4 4 4 1 Coatomer epsilon subunit Apc5 PF12862.2 KII86051.1 - 0.0048 16.7 0.1 0.82 9.5 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_4 PF07721.9 KII86051.1 - 0.012 15.9 3.0 27 5.5 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec8_exocyst PF04048.9 KII86051.1 - 0.054 13.1 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MIT PF04212.13 KII86051.1 - 0.054 13.3 4.0 39 4.2 0.0 4.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain FadA PF09403.5 KII86051.1 - 0.068 13.1 3.0 0.52 10.3 0.0 3.0 4 0 0 4 4 3 0 Adhesion protein FadA TPR_21 PF09976.4 KII86051.1 - 5.4 6.9 12.9 2 8.3 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 KII86052.1 - 1.3e-49 164.3 24.4 1.2e-11 44.0 0.4 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 KII86052.1 - 3.8e-09 36.1 5.3 3.8e-09 36.1 3.7 2.0 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 KII86052.1 - 2.9e-05 22.4 5.7 0.88 7.6 0.1 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII86052.1 - 0.08 11.6 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like PQQ_3 PF13570.1 KII86052.1 - 3.1 8.2 6.7 39 4.7 0.0 4.9 5 1 0 5 5 5 0 PQQ-like domain DNA_pol_delta_4 PF04081.8 KII86053.1 - 1.5e-24 86.6 0.1 2.6e-24 85.8 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Ashwin PF15323.1 KII86053.1 - 7.6 6.4 11.2 14 5.5 7.7 1.4 1 1 0 1 1 1 0 Developmental protein WLM PF08325.5 KII86054.1 - 6.2e-30 104.4 0.0 1.2e-29 103.5 0.0 1.4 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.18 KII86054.1 - 1.6e-07 30.6 0.0 3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KII86054.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Peptidase_MA_2 PF13485.1 KII86054.1 - 0.038 14.0 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 KII86054.1 - 0.11 12.1 0.2 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF45 PF01863.12 KII86054.1 - 0.18 11.6 0.9 0.36 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 zf-HC5HC2H_2 PF13832.1 KII86055.1 - 1e-34 118.7 9.6 3.6e-34 117.0 3.7 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KII86055.1 - 1.5e-25 89.1 3.3 1.5e-25 89.1 2.3 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KII86055.1 - 2.6e-22 79.7 1.8 1e-21 77.8 1.2 2.0 1 0 0 1 1 1 1 Enhancer of polycomb-like Bromodomain PF00439.20 KII86055.1 - 6.4e-18 64.4 0.2 1.3e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 KII86055.1 - 7.8e-15 53.9 3.1 7.8e-15 53.9 2.2 2.9 3 0 0 3 3 3 1 PHD-finger PWWP PF00855.12 KII86055.1 - 1.2e-13 51.0 0.0 3.3e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 KII86055.1 - 5.7e-10 38.7 21.7 7.1e-10 38.4 3.9 2.7 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 KII86055.1 - 0.0044 16.3 1.0 0.0044 16.3 0.7 2.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KII86055.1 - 0.01 15.5 0.2 0.01 15.5 0.1 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KII86055.1 - 1.2 9.2 19.7 0.31 11.0 3.1 3.3 2 1 1 3 3 3 0 RING-like domain Prok-RING_1 PF14446.1 KII86055.1 - 8.5 6.1 13.5 0.34 10.6 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Lipase_GDSL PF00657.17 KII86056.1 - 4.5e-12 46.2 0.2 7e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 KII86056.1 - 3.2e-10 39.4 6.3 3.2e-10 39.4 4.3 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain RNA_pol_Rbc25 PF08292.7 KII86057.1 - 2.4e-31 108.4 0.0 3e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KII86057.1 - 7.1e-21 74.1 0.1 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Amidase PF01425.16 KII86058.1 - 2e-112 376.2 4.1 2.5e-112 375.9 2.9 1.0 1 0 0 1 1 1 1 Amidase Lipase_GDSL PF00657.17 KII86059.1 - 8.1e-08 32.3 0.6 1.3e-07 31.6 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Mito_carr PF00153.22 KII86060.1 - 3.2e-66 219.0 0.7 6.9e-22 76.9 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KII86061.1 - 8.6e-23 79.3 3.9 3.8e-10 39.2 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 KII86061.1 - 0.0015 16.7 0.0 0.0087 14.2 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 RNA_pol_Rpc4 PF05132.9 KII86061.1 - 0.057 13.4 0.2 0.47 10.4 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase III RPC4 WD40 PF00400.27 KII86062.1 - 0.011 15.5 0.2 3.5 7.6 0.1 2.8 2 1 0 2 2 2 0 WD domain, G-beta repeat CDC45 PF02724.9 KII86062.1 - 1.2 7.0 9.8 1.2 7.0 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 KII86062.1 - 4.3 6.6 14.8 5.3 6.3 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 KII86062.1 - 9.7 3.9 28.3 11 3.7 19.6 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 KII86062.1 - 9.8 5.9 15.5 10 5.8 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1604 PF07713.8 KII86063.1 - 5.6e-37 125.3 1.3 5.6e-37 125.3 0.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KII86063.1 - 1.7e-05 24.5 0.8 1.7e-05 24.5 0.5 3.4 3 0 0 3 3 3 1 G-patch domain Aldose_epim PF01263.15 KII86064.1 - 1.6e-26 93.1 0.0 1.9e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.1 KII86064.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) AA_permease PF00324.16 KII86065.1 - 1.8e-123 412.4 38.0 2.1e-123 412.2 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII86065.1 - 2.8e-36 124.9 41.3 3.8e-36 124.5 28.6 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_21 PF13506.1 KII86065.1 - 0.099 11.9 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Methyltransf_23 PF13489.1 KII86066.1 - 1.2e-14 54.3 0.0 3.3e-14 52.9 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII86066.1 - 7e-11 42.4 0.0 6.3e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII86066.1 - 6.8e-10 39.3 0.0 7.6e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KII86066.1 - 4e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86066.1 - 8.2e-08 32.8 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII86066.1 - 9.4e-06 25.2 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII86066.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 KII86066.1 - 0.0014 17.4 0.0 0.0028 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 KII86066.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KII86066.1 - 0.017 14.1 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family CheR PF01739.13 KII86066.1 - 0.03 13.6 0.0 5.8 6.1 0.0 2.4 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.1 KII86066.1 - 0.039 14.7 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KII86066.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Mif2_N PF15624.1 KII86067.1 - 2.1 8.9 6.2 3.1 8.3 4.3 1.3 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RhoGEF PF00621.15 KII86068.1 - 9.5e-68 227.6 3.4 4.1e-33 114.7 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 KII86068.1 - 1.3e-60 205.2 0.0 2e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KII86068.1 - 1.1e-16 60.9 0.0 2.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KII86068.1 - 1.6e-05 25.0 0.0 5.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 PH domain DEP PF00610.16 KII86068.1 - 8.1e-05 22.2 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Erythro_esteras PF05139.9 KII86068.1 - 0.025 13.7 0.6 0.042 13.0 0.4 1.3 1 0 0 1 1 1 0 Erythromycin esterase CNH PF00780.17 KII86069.1 - 3.2e-41 141.5 0.0 3.8e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 CNH domain 4HBT_2 PF13279.1 KII86070.1 - 8.2e-12 45.6 0.0 1.6e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KII86070.1 - 2.5e-06 27.4 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KII86070.1 - 0.0057 15.6 0.0 0.056 12.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-ACP thioesterase Cellulase PF00150.13 KII86072.1 - 1.6e-12 47.2 0.0 3.3e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DAGAT PF03982.8 KII86073.1 - 6.1e-103 343.5 0.0 7.7e-103 343.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CAP_GLY PF01302.20 KII86074.1 - 1e-26 92.4 1.1 1.9e-26 91.5 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KII86074.1 - 1.3e-23 83.0 0.0 2.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KII86074.1 - 0.08 12.3 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family AAA PF00004.24 KII86075.1 - 2.2e-96 319.1 0.0 8.6e-47 158.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KII86075.1 - 1.2e-19 69.9 0.5 1.9e-18 66.1 0.3 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KII86075.1 - 9.9e-14 50.9 0.0 1.9e-05 23.8 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KII86075.1 - 1.6e-13 50.9 0.0 1.3e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KII86075.1 - 2.5e-13 50.1 0.0 1.2e-06 28.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KII86075.1 - 3.9e-13 50.2 0.0 0.00015 22.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KII86075.1 - 3.1e-12 46.3 0.6 7.6e-06 25.6 0.1 3.8 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KII86075.1 - 1.5e-11 44.5 0.1 0.0011 19.1 0.0 4.3 3 2 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 KII86075.1 - 3e-11 42.7 0.0 7.2e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 KII86075.1 - 8.6e-10 37.8 0.1 0.0012 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KII86075.1 - 4.4e-09 36.5 0.0 0.0088 16.0 0.0 3.3 2 2 1 3 3 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KII86075.1 - 1.9e-08 33.6 0.0 0.0078 15.3 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_25 PF13481.1 KII86075.1 - 2e-08 33.8 2.0 0.0056 16.1 0.0 3.7 2 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KII86075.1 - 3.2e-08 33.1 0.0 0.0034 16.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KII86075.1 - 7.3e-08 31.8 0.4 0.0047 16.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KII86075.1 - 7.7e-08 32.2 0.0 0.0075 16.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KII86075.1 - 5e-07 29.3 1.1 0.019 14.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Vps4_C PF09336.5 KII86075.1 - 5.1e-07 29.4 0.1 5.8e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 KII86075.1 - 1.2e-06 28.6 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 KII86075.1 - 1.9e-06 28.1 0.2 0.041 14.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KII86075.1 - 2.8e-06 27.3 0.0 0.052 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 KII86075.1 - 5e-06 25.8 0.7 0.86 8.6 0.1 3.5 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 KII86075.1 - 5.2e-06 25.5 0.2 0.005 15.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 KII86075.1 - 6.8e-06 26.0 0.0 0.0052 16.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 KII86075.1 - 1.4e-05 24.6 0.0 0.28 10.6 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KII86075.1 - 1.7e-05 25.0 0.0 0.11 12.8 0.0 3.6 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 KII86075.1 - 2e-05 24.2 0.1 0.061 12.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 KII86075.1 - 4.6e-05 22.4 0.0 0.015 14.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 KII86075.1 - 4.7e-05 23.4 0.0 0.33 11.0 0.0 3.0 3 0 0 3 3 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KII86075.1 - 5.8e-05 22.9 0.0 2 8.0 0.0 3.8 3 1 1 4 4 3 1 Archaeal ATPase Bac_DnaA PF00308.13 KII86075.1 - 7.1e-05 22.5 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_11 PF13086.1 KII86075.1 - 8.2e-05 22.2 0.0 0.49 9.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 KII86075.1 - 8.4e-05 21.8 0.2 0.46 9.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 KII86075.1 - 8.4e-05 22.2 0.1 0.092 12.3 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 KII86075.1 - 0.00014 21.4 0.0 0.39 10.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KII86075.1 - 0.00037 20.0 0.0 0.12 11.8 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KII86075.1 - 0.0007 19.2 0.0 0.83 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KII86075.1 - 0.0018 17.2 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 KII86075.1 - 0.0021 17.0 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KII86075.1 - 0.0037 17.0 0.3 1.2 8.8 0.0 3.4 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.17 KII86075.1 - 0.006 15.4 0.3 0.39 9.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.11 KII86075.1 - 0.017 14.2 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 KII86075.1 - 0.018 14.0 0.0 0.69 8.8 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain Cytidylate_kin2 PF13189.1 KII86075.1 - 0.022 14.6 1.4 3.1 7.6 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family AAA_10 PF12846.2 KII86075.1 - 0.022 14.1 1.7 1.6 8.0 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain ATP-synt_ab PF00006.20 KII86075.1 - 0.023 14.1 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 KII86075.1 - 0.027 14.1 0.9 2 8.0 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 UFD1 PF03152.9 KII86075.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 SKI PF01202.17 KII86075.1 - 0.037 13.8 0.8 3.5 7.4 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase KTI12 PF08433.5 KII86075.1 - 0.052 12.7 0.0 6.9 5.7 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MobB PF03205.9 KII86075.1 - 0.065 12.9 0.1 5.9 6.5 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AFG1_ATPase PF03969.11 KII86075.1 - 0.084 11.6 0.0 7.4 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.1 KII86075.1 - 0.088 13.1 0.5 0.88 9.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain ADK_lid PF05191.9 KII86077.1 - 1.3 8.7 4.5 0.29 10.8 0.4 2.0 2 1 0 2 2 2 0 Adenylate kinase, active site lid SE PF08491.5 KII86078.1 - 2.3e-96 321.8 0.0 3.1e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KII86078.1 - 3.3e-13 49.4 0.2 2.5e-08 33.3 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KII86078.1 - 1.8e-11 43.5 0.1 1e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII86078.1 - 0.0001 21.3 3.5 0.02 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KII86078.1 - 0.00016 20.7 0.3 0.035 13.0 0.6 2.6 2 1 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 KII86078.1 - 0.00078 18.1 0.2 0.4 9.2 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KII86078.1 - 0.00082 19.1 0.3 0.082 12.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KII86078.1 - 0.018 15.0 0.1 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII86078.1 - 0.056 12.5 0.1 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KII86078.1 - 0.19 11.5 1.4 0.46 10.3 0.9 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII86078.1 - 0.43 9.3 2.9 4.3 6.0 2.0 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A DnaJ PF00226.26 KII86079.1 - 2e-10 40.2 0.0 3.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain GMC_oxred_N PF00732.14 KII86080.1 - 1.4e-58 198.4 0.1 2.2e-58 197.7 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII86080.1 - 8.1e-34 116.9 0.0 1.5e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KII86080.1 - 0.00016 21.6 0.1 0.00045 20.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII86080.1 - 0.002 17.0 0.3 0.0075 15.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KII86080.1 - 0.0068 15.3 0.6 0.013 14.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII86080.1 - 0.013 14.4 0.4 0.02 13.8 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KII86080.1 - 0.02 14.9 0.1 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1727 PF08353.5 KII86081.1 - 0.05 13.2 3.1 0.18 11.4 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1727) Takusan PF04822.8 KII86081.1 - 0.4 10.4 0.0 0.4 10.4 0.0 3.9 3 1 1 4 4 4 0 Takusan Cu-oxidase PF00394.17 KII86082.1 - 3.5e-45 153.7 0.1 1.2e-41 142.2 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KII86082.1 - 2.5e-40 137.1 4.6 1.7e-38 131.2 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KII86082.1 - 2.4e-38 130.4 0.9 4.6e-35 119.9 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase FAD_binding_3 PF01494.14 KII86083.1 - 2.6e-19 69.4 0.5 9.2e-18 64.4 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KII86083.1 - 0.0002 21.3 0.1 0.00061 19.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KII86083.1 - 0.1 11.0 0.6 0.18 10.2 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KII86084.1 - 1.8e-19 70.0 0.0 4.1e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KII86084.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KII86084.1 - 0.011 14.4 0.7 0.17 10.4 0.1 2.4 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KII86084.1 - 0.059 13.4 0.3 0.19 11.7 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KII86084.1 - 0.081 12.6 0.3 15 5.2 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KII86085.1 - 1.5e-12 47.2 0.0 1.8e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KII86085.1 - 0.039 12.7 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.1 KII86086.1 - 1.5e-05 24.9 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII86086.1 - 0.00023 20.1 0.3 0.00029 19.8 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII86086.1 - 0.00036 19.5 0.2 0.00063 18.7 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII86086.1 - 0.00099 19.0 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII86086.1 - 0.0064 15.0 0.1 0.0095 14.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KII86086.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KII86086.1 - 0.035 13.1 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KII86086.1 - 0.037 12.9 0.1 0.048 12.5 0.1 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KII86086.1 - 0.06 13.3 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII86086.1 - 0.074 12.1 0.3 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII86087.1 - 2.4e-17 63.0 0.0 2.2e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DUF4243 PF14027.1 KII86089.1 - 1.8e-63 215.0 0.5 9.2e-62 209.3 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) SRF-TF PF00319.13 KII86090.1 - 3.7e-19 67.7 0.0 7.8e-19 66.6 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Methyltransf_15 PF09445.5 KII86092.1 - 8e-37 126.3 0.0 1e-27 96.7 0.0 2.3 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KII86092.1 - 4.8e-09 36.2 0.0 8.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86092.1 - 4.8e-08 33.5 0.0 9.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII86092.1 - 1.1e-06 28.9 0.0 3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII86092.1 - 4.3e-06 26.3 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KII86092.1 - 0.0001 21.9 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KII86092.1 - 0.00018 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 KII86092.1 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 KII86092.1 - 0.007 16.8 0.0 0.018 15.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 KII86092.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 KII86092.1 - 0.045 13.2 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase tRNA_U5-meth_tr PF05958.6 KII86092.1 - 0.095 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase SAM_MT PF04445.8 KII86092.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MULE PF10551.4 KII86095.1 - 1.6e-08 34.5 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 KII86095.1 - 0.035 14.6 0.6 0.078 13.5 0.4 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain HEAT_2 PF13646.1 KII86096.1 - 1.6e-11 44.3 14.8 0.0052 17.0 0.0 6.8 6 1 1 7 7 7 5 HEAT repeats Arm PF00514.18 KII86096.1 - 0.021 14.6 3.9 0.029 14.2 0.0 3.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KII86096.1 - 0.034 14.2 16.6 1.3 9.2 0.0 7.6 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.1 KII86096.1 - 0.29 11.6 0.1 0.29 11.6 0.0 8.1 9 1 0 9 9 9 0 HEAT-like repeat zf-MYND PF01753.13 KII86097.1 - 1.7e-12 47.0 14.8 3e-12 46.2 10.2 1.4 1 0 0 1 1 1 1 MYND finger CENP-M PF11111.3 KII86097.1 - 0.039 13.1 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) RIH_assoc PF08454.6 KII86097.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated zf-Mss51 PF13824.1 KII86097.1 - 0.38 10.6 5.6 0.9 9.4 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 AAA_2 PF07724.9 KII86098.1 - 1.3e-45 155.3 0.0 2.4e-42 144.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KII86098.1 - 3.7e-21 74.8 1.4 6e-21 74.1 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KII86098.1 - 5.3e-19 68.7 0.1 3.4e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII86098.1 - 1.7e-17 63.4 0.0 1.7e-10 40.7 0.0 3.0 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KII86098.1 - 6.4e-12 45.8 4.1 7.4e-06 26.0 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KII86098.1 - 1.1e-09 38.4 0.0 0.0011 19.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KII86098.1 - 5.4e-08 32.5 0.0 2e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KII86098.1 - 4.1e-07 29.9 0.0 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KII86098.1 - 9.1e-07 28.4 0.0 0.036 13.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KII86098.1 - 1.5e-06 27.5 0.1 0.081 12.0 0.0 3.0 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KII86098.1 - 2.2e-06 27.9 1.2 0.035 14.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KII86098.1 - 2.3e-06 28.4 5.1 0.069 13.9 0.2 3.9 3 1 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KII86098.1 - 3.3e-06 26.9 5.0 0.0052 16.5 0.1 3.9 3 1 0 3 3 3 2 Archaeal ATPase AAA_19 PF13245.1 KII86098.1 - 2e-05 24.2 0.0 0.036 13.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 KII86098.1 - 5.5e-05 23.1 0.9 0.2 11.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.22 KII86098.1 - 7.6e-05 23.0 2.8 0.01 16.1 0.0 3.1 3 1 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 KII86098.1 - 9.4e-05 21.8 0.0 0.32 10.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KII86098.1 - 0.00013 21.0 0.5 0.49 9.3 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KII86098.1 - 0.00026 20.2 0.0 0.69 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KII86098.1 - 0.00058 20.0 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 KII86098.1 - 0.0015 18.2 0.1 2.1 8.0 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KII86098.1 - 0.0022 17.1 0.6 0.15 11.0 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.7 KII86098.1 - 0.003 17.2 0.0 0.38 10.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 KII86098.1 - 0.003 17.0 0.0 2.9 7.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 KII86098.1 - 0.0046 16.6 0.5 2 8.1 0.0 3.8 4 0 0 4 4 3 1 NTPase T2SE PF00437.15 KII86098.1 - 0.0058 15.5 0.2 0.099 11.5 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KII86098.1 - 0.014 15.3 0.6 5.1 7.0 0.0 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase ResIII PF04851.10 KII86098.1 - 0.016 15.0 0.1 13 5.5 0.0 3.5 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KII86098.1 - 0.017 14.7 0.1 5.2 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KII86098.1 - 0.022 14.6 0.0 5.7 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KII86098.1 - 0.029 14.8 0.6 0.63 10.5 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_10 PF12846.2 KII86098.1 - 0.039 13.3 0.6 9.8 5.5 0.0 3.3 2 2 1 3 3 3 0 AAA-like domain SRP54 PF00448.17 KII86098.1 - 0.044 13.2 0.0 5.1 6.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.1 KII86098.1 - 0.044 13.4 0.0 0.43 10.2 0.0 2.5 3 1 0 3 3 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.6 KII86098.1 - 0.057 13.0 0.0 20 4.8 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KII86098.1 - 0.069 12.6 0.0 2 7.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KII86098.1 - 0.071 13.0 0.1 4.1 7.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KII86098.1 - 0.085 13.1 16.5 0.17 12.1 0.0 3.5 3 1 0 3 3 2 0 AAA domain APG6 PF04111.7 KII86098.1 - 2 7.3 10.8 3.1 6.7 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3808 PF10300.4 KII86100.1 - 1.7e-69 234.6 0.0 2.6e-69 234.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KII86100.1 - 3.2e-08 33.0 5.5 0.014 15.0 0.1 4.7 3 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 KII86100.1 - 4.9e-05 23.1 3.2 0.1 12.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII86100.1 - 0.00018 21.1 7.7 0.041 13.8 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII86100.1 - 0.005 16.3 3.5 1.6 8.4 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII86100.1 - 0.54 11.0 6.2 17 6.2 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII86100.1 - 1.1 9.8 3.3 58 4.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat K_trans PF02705.11 KII86101.1 - 1.8e-171 571.1 17.4 2.3e-171 570.8 12.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter Glyco_hydro_15 PF00723.16 KII86105.1 - 2.2e-95 319.8 0.2 2.6e-95 319.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GCV_T PF01571.16 KII86106.1 - 2e-63 213.5 0.0 2.6e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KII86106.1 - 6.2e-24 83.8 0.2 1.2e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF1466 PF07326.6 KII86107.1 - 0.039 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) Di19_C PF14571.1 KII86108.1 - 1.6 9.1 5.7 0.21 11.9 0.7 1.9 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal SHS2_Rpb7-N PF03876.12 KII86109.1 - 7.1e-14 51.6 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KII86109.1 - 1.9e-11 43.8 1.0 5.3e-11 42.4 0.7 1.7 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KII86109.1 - 0.0094 16.1 0.1 0.017 15.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 BNR PF02012.15 KII86110.1 - 2.9e-12 44.4 41.1 0.24 11.3 0.1 12.5 11 0 0 11 11 11 8 BNR/Asp-box repeat Fe_dep_repr_C PF02742.10 KII86110.1 - 0.0024 17.5 0.0 0.057 13.1 0.0 2.8 3 0 0 3 3 3 1 Iron dependent repressor, metal binding and dimerisation domain Mo-co_dimer PF03404.11 KII86110.1 - 0.05 13.2 1.4 9.7 5.8 0.0 5.1 5 2 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain Herpes_US9 PF06072.6 KII86114.1 - 1.2 8.9 5.5 9.6 6.1 0.3 2.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 AAA_16 PF13191.1 KII86116.1 - 4.6e-07 29.9 0.0 0.0064 16.4 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KII86116.1 - 0.00051 19.7 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KII86116.1 - 0.0036 17.4 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KII86116.1 - 0.0086 14.9 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 KII86116.1 - 0.086 12.2 0.1 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_P4 PF11602.3 KII86116.1 - 0.12 11.2 0.0 0.32 9.9 0.0 1.6 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 Sigma54_activat PF00158.21 KII86116.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KII86117.1 - 4.9e-07 29.9 0.1 0.0014 18.6 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KII86117.1 - 0.00078 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KII86117.1 - 0.0011 17.8 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 KII86117.1 - 0.006 16.0 1.3 0.97 8.8 0.5 2.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KII86117.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SAM_adeno_trans PF01887.11 KII86117.1 - 0.045 12.8 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Sigma54_activat PF00158.21 KII86117.1 - 0.097 12.1 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.17 KII86117.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF998 PF06197.8 KII86119.1 - 0.17 11.1 2.2 0.13 11.5 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF998) ANF_receptor PF01094.23 KII86119.1 - 7.9 5.1 8.5 11 4.6 5.9 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region DUF605 PF04652.11 KII86124.1 - 0.53 9.6 13.9 0.66 9.3 9.7 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KII86124.1 - 2 8.2 4.1 2.3 8.0 2.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 KII86125.1 - 2.4 7.1 17.9 0.041 12.9 7.5 1.6 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.7 KII86125.1 - 3.9 5.2 21.2 5.1 4.8 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family HGTP_anticodon2 PF12745.2 KII86125.1 - 9.1 5.3 11.4 29 3.6 7.9 1.8 1 1 0 1 1 1 0 Anticodon binding domain of tRNAs AAA_16 PF13191.1 KII86128.1 - 4.5e-09 36.5 0.0 2.1e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KII86128.1 - 9.3e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KII86128.1 - 0.001 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KII86128.1 - 0.0074 15.1 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KII86128.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KII86128.1 - 0.064 12.6 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KII86128.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KII86128.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KII86128.1 - 0.14 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1900 PF08954.6 KII86129.1 - 4.8e-47 158.8 0.0 1.2e-46 157.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 KII86129.1 - 5.6e-23 79.9 1.6 1.4e-07 31.1 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 KII86129.1 - 4.2e-16 58.3 0.0 8.2e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Pup PF05639.6 KII86133.1 - 1.7 9.1 6.0 0.59 10.6 1.7 2.0 1 1 1 2 2 2 0 Pup-like protein DUF4218 PF13960.1 KII86134.1 - 2e-05 24.0 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DM PF00751.13 KII86134.1 - 0.0033 16.9 0.6 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 DM DNA binding domain Transposase_21 PF02992.9 KII86134.1 - 0.012 14.6 1.0 0.017 14.1 0.0 1.6 2 0 0 2 2 2 0 Transposase family tnp2 zf-MYND PF01753.13 KII86136.1 - 1.2e-10 41.0 9.6 2.1e-10 40.3 6.6 1.4 1 0 0 1 1 1 1 MYND finger DUF2267 PF10025.4 KII86136.1 - 0.0089 16.0 0.2 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) zf-Mss51 PF13824.1 KII86136.1 - 0.27 11.1 4.3 0.15 11.9 0.9 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KII86139.1 - 4.1e-11 42.5 4.9 1.1e-10 41.2 3.4 1.8 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII86139.1 - 0.053 13.3 0.7 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Gag_p12 PF01141.13 KII86139.1 - 0.058 13.5 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 Ecl1 PF12855.2 KII86139.1 - 0.68 9.2 3.0 1.4 8.2 2.1 1.5 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KII86140.1 - 2.7e-09 36.7 11.3 5.4e-09 35.7 7.8 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII86140.1 - 0.074 12.9 5.1 0.2 11.5 3.5 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 adh_short_C2 PF13561.1 KII86142.1 - 2e-26 93.2 0.1 2.4e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII86142.1 - 3.9e-09 36.6 1.8 5.4e-09 36.1 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Oxidored_nitro PF00148.14 KII86142.1 - 0.0014 17.3 0.0 0.0014 17.3 0.0 1.2 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.16 KII86142.1 - 0.013 15.3 0.3 0.025 14.4 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII86142.1 - 0.026 13.7 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF694 PF05107.7 KII86142.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) F-box-like PF12937.2 KII86143.1 - 4e-11 42.4 0.3 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII86144.1 - 2.8e-09 36.5 0.0 6.3e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86144.1 - 0.012 15.3 0.2 0.043 13.4 0.2 2.0 1 1 0 1 1 1 0 F-box domain F-box PF00646.28 KII86145.1 - 0.00018 21.0 0.0 0.00079 19.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII86145.1 - 0.01 15.5 1.4 0.031 14.0 0.0 2.6 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.2 KII86147.1 - 2.9e-10 39.7 3.7 5.9e-10 38.7 2.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86147.1 - 0.0015 18.0 1.9 0.0015 18.0 1.3 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII86148.1 - 6.3e-11 41.8 0.8 1.7e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII86148.1 - 2.4 7.9 5.0 3.3 7.4 0.1 3.1 3 1 1 4 4 4 0 F-box domain BTB PF00651.26 KII86149.1 - 1.8e-05 24.7 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII86150.1 - 3.2e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 KII86151.1 - 3.7e-08 32.9 2.2 3.7e-08 32.9 1.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII86151.1 - 0.01 15.4 0.6 0.053 13.1 0.4 2.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KII86152.1 - 2.9e-08 33.3 0.0 7.2e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII86152.1 - 9.8e-05 21.8 0.7 8.2 6.1 0.1 4.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KII86153.1 - 1.1e-08 34.6 0.0 4e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86153.1 - 0.0028 17.2 0.0 0.0099 15.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KII86153.1 - 0.23 11.1 1.5 22 4.7 0.2 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Lipase_GDSL PF00657.17 KII86154.1 - 8.9e-13 48.6 0.1 1.7e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KII86154.1 - 3.6e-07 30.4 0.3 5.4e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GLTP PF08718.6 KII86155.1 - 9e-33 113.4 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) F-box-like PF12937.2 KII86156.1 - 3.4e-08 33.0 0.1 1.5e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like Ribosomal_L7Ae PF01248.21 KII86157.1 - 1.1e-22 79.2 0.9 1.9e-22 78.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adenine_glyco PF03352.8 KII86157.1 - 0.13 11.7 0.5 0.29 10.6 0.3 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase FAD_binding_3 PF01494.14 KII86158.1 - 3.7e-65 220.3 0.0 5e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII86158.1 - 1e-06 28.7 0.1 2.1e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII86158.1 - 3.6e-06 25.7 0.2 1.1e-05 24.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KII86158.1 - 4.2e-06 25.8 0.9 6.7e-06 25.2 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KII86158.1 - 2.2e-05 24.4 0.0 6.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KII86158.1 - 8.2e-05 21.6 0.1 0.00012 21.1 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KII86158.1 - 0.00011 22.5 0.4 0.13 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII86158.1 - 0.00023 20.1 0.1 0.0019 17.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KII86158.1 - 0.00032 19.8 0.2 0.0008 18.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KII86158.1 - 0.00055 20.0 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII86158.1 - 0.0012 17.9 1.1 0.0029 16.7 0.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII86158.1 - 0.011 14.7 0.2 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 KII86158.1 - 0.029 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family LEA_6 PF10714.4 KII86158.1 - 0.032 14.0 0.1 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 3HCDH_N PF02737.13 KII86158.1 - 0.035 13.7 0.1 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KII86158.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding zf-C2H2_6 PF13912.1 KII86160.1 - 0.015 15.1 1.9 0.038 13.9 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KII86160.1 - 5.6 7.5 9.6 0.21 12.0 1.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type ERCC4 PF02732.10 KII86162.1 - 6.9e-27 93.9 0.0 1.4e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Cir_N PF10197.4 KII86163.1 - 5.6e-05 23.0 0.5 5.6e-05 23.0 0.3 2.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CENP-Q PF13094.1 KII86163.1 - 0.37 10.7 4.7 5.4 7.0 3.3 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Lipase_3 PF01764.20 KII86164.1 - 3.6e-19 68.7 0.1 4.9e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KII86164.1 - 0.032 13.7 0.4 0.13 11.7 0.1 2.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII86164.1 - 0.066 13.0 0.4 0.3 10.9 0.2 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII86164.1 - 0.094 12.4 1.1 0.29 10.9 0.8 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 KII86165.1 - 2.1e-05 24.1 0.0 9.3e-05 22.0 0.0 2.2 1 0 0 1 1 1 1 F-box-like Snapin_Pallidin PF14712.1 KII86166.1 - 0.0033 17.7 1.0 0.0033 17.7 0.7 2.1 2 0 0 2 2 2 1 Snapin/Pallidin DUF3166 PF11365.3 KII86166.1 - 0.011 16.1 2.4 0.13 12.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Myosin_tail_1 PF01576.14 KII86166.1 - 0.018 12.8 11.0 0.023 12.4 7.7 1.1 1 0 0 1 1 1 0 Myosin tail Herpes_UL25 PF01499.11 KII86166.1 - 0.064 11.5 10.4 0.091 11.0 7.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Tropomyosin_1 PF12718.2 KII86166.1 - 0.27 11.0 6.3 0.56 10.0 4.3 1.5 1 0 0 1 1 1 0 Tropomyosin like Ead_Ea22 PF13935.1 KII86166.1 - 0.29 11.4 5.7 1.5 9.1 3.9 2.2 1 1 0 1 1 1 0 Ead/Ea22-like protein EURL PF06937.6 KII86166.1 - 0.34 10.2 4.7 0.48 9.8 3.3 1.1 1 0 0 1 1 1 0 EURL protein IncA PF04156.9 KII86166.1 - 0.5 9.9 15.0 0.31 10.5 7.0 2.2 1 1 1 2 2 2 0 IncA protein STAT_alpha PF01017.15 KII86166.1 - 0.53 9.9 7.8 4.8 6.8 2.0 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain WXG100 PF06013.7 KII86166.1 - 0.66 10.0 10.9 0.1 12.6 2.1 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.4 KII86166.1 - 0.97 9.2 6.9 2.4 8.0 4.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 KII86166.1 - 1.5 8.6 7.4 0.71 9.7 0.5 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Syntaxin PF00804.20 KII86166.1 - 3.3 7.9 6.6 1.3 9.1 1.1 2.3 1 1 1 2 2 2 0 Syntaxin UBN2 PF14223.1 KII86168.1 - 1.6e-11 44.0 0.0 1.7e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII86168.1 - 5.7e-07 29.1 0.0 6.1e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1877 PF08974.5 KII86168.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) UBN2_3 PF14244.1 KII86168.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type F-box-like PF12937.2 KII86169.1 - 0.00027 20.5 0.2 0.001 18.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII86170.1 - 5.2e-05 22.8 0.1 0.00021 20.9 0.1 2.1 1 0 0 1 1 1 1 F-box-like GST_N_2 PF13409.1 KII86171.1 - 1.8e-22 79.1 0.0 3.7e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII86171.1 - 2.2e-14 53.0 0.0 5.6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII86171.1 - 3.1e-07 30.2 0.0 5.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII86171.1 - 2.6e-05 24.3 0.0 0.00044 20.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII86171.1 - 0.00054 20.3 0.0 0.00096 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipase_3 PF01764.20 KII86173.1 - 2.5e-19 69.2 0.0 3.6e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KII86173.1 - 0.016 15.0 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 KII86174.1 - 9.1e-68 228.8 0.0 1e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3482 PF11981.3 KII86174.1 - 0.068 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) GST_N_2 PF13409.1 KII86175.1 - 1.6e-21 76.0 0.1 8.6e-21 73.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII86175.1 - 6.5e-16 57.9 0.0 1.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII86175.1 - 2.6e-08 33.7 0.0 4.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII86175.1 - 6.1e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII86175.1 - 0.00014 21.9 0.0 0.0024 18.0 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ATP_synt_I PF03899.10 KII86178.1 - 0.014 15.5 11.3 0.026 14.6 0.7 2.7 2 1 0 2 2 2 0 ATP synthase I chain F-box-like PF12937.2 KII86179.1 - 0.0013 18.4 1.3 0.0074 15.9 0.9 2.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII86181.1 - 1.4e-05 24.7 0.6 3.8e-05 23.3 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII86181.1 - 0.045 13.3 0.1 0.44 10.2 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII86181.1 - 0.15 11.8 0.7 0.38 10.5 0.0 2.0 3 0 0 3 3 3 0 Leucine rich repeat DUF904 PF06005.7 KII86181.1 - 2.4 8.5 6.9 6.4 7.1 4.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) F-box-like PF12937.2 KII86182.1 - 1.1e-07 31.5 0.9 4.2e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII86182.1 - 0.67 9.6 3.9 2.8 7.6 0.2 3.1 3 0 0 3 3 3 0 F-box domain EutQ PF06249.7 KII86183.1 - 1.2e-11 44.3 0.3 1.3e-11 44.2 0.2 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KII86183.1 - 0.00068 18.9 0.1 0.00094 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Pox_RNA_pol PF03293.9 KII86183.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Cupin_2 PF07883.6 KII86183.1 - 0.018 14.5 0.1 0.087 12.3 0.0 1.9 1 1 1 2 2 2 0 Cupin domain Cupin_6 PF12852.2 KII86183.1 - 0.042 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Cupin PIG-F PF06699.6 KII86184.1 - 0.017 15.0 0.7 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F F-box-like PF12937.2 KII86185.1 - 0.00018 21.1 0.1 0.00047 19.8 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII86186.1 - 0.00053 19.6 0.3 0.0038 16.9 0.2 2.4 2 0 0 2 2 2 1 F-box-like DUF43 PF01861.11 KII86186.1 - 0.16 10.9 0.0 5.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF43 DEAD PF00270.24 KII86188.1 - 3.3e-19 68.9 0.0 5.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII86188.1 - 1.1e-13 50.7 0.0 3.6e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII86188.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KII86188.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain DUF2620 PF10941.3 KII86188.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 zf-CCHC PF00098.18 KII86189.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.0 2 0 0 2 2 2 0 Zinc knuckle Glyco_tranf_2_4 PF13704.1 KII86190.1 - 0.1 12.9 0.3 0.23 11.8 0.2 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF3565 PF12088.3 KII86190.1 - 0.14 11.9 0.6 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) 4HBT PF03061.17 KII86193.1 - 2.1e-13 50.1 0.0 3.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KII86193.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 2.0 2 1 0 2 2 2 1 Thioesterase-like superfamily F-box-like PF12937.2 KII86194.1 - 1e-06 28.3 0.2 2.9e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII86195.1 - 0.0001 21.9 0.1 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Phosducin PF02114.11 KII86196.1 - 6e-16 57.9 0.1 5e-06 25.4 0.0 3.1 2 1 1 3 3 3 3 Phosducin Glyco_hydro_61 PF03443.9 KII86197.1 - 1.7e-64 217.6 0.6 1.9e-64 217.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F-box-like PF12937.2 KII86198.1 - 0.18 11.5 5.0 0.34 10.6 0.7 2.9 3 0 0 3 3 3 0 F-box-like OTT_1508_deam PF14441.1 KII86200.1 - 0.012 15.4 0.1 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase DUF659 PF04937.10 KII86202.1 - 0.009 15.5 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 KII86202.1 - 0.087 12.4 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region TPR_12 PF13424.1 KII86203.1 - 1.7e-36 124.0 29.6 3.4e-09 36.5 1.9 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 KII86203.1 - 1.6e-29 99.3 32.4 0.0024 17.6 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KII86203.1 - 1.3e-24 86.2 27.2 0.00014 22.3 0.7 9.0 3 1 4 8 8 8 7 Tetratricopeptide repeat SNAP PF14938.1 KII86203.1 - 9.6e-20 70.8 32.8 8e-09 35.0 2.4 3.9 1 1 4 5 5 5 5 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KII86203.1 - 2.4e-19 68.7 24.4 0.0001 21.9 0.7 6.7 4 2 3 7 7 7 5 TPR repeat TPR_10 PF13374.1 KII86203.1 - 5.7e-13 48.3 31.0 0.11 12.5 0.5 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KII86203.1 - 5.9e-12 45.7 37.3 0.016 15.4 3.6 7.4 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 KII86203.1 - 6.3e-11 41.3 27.5 0.45 10.2 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KII86203.1 - 9.4e-09 35.2 16.2 0.038 14.1 0.3 5.5 1 1 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 KII86203.1 - 7.2e-08 32.4 27.2 0.018 14.9 0.6 5.3 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KII86203.1 - 1.3e-06 28.1 20.2 16 5.9 0.0 9.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII86203.1 - 1.1e-05 25.5 27.9 6 7.7 0.2 9.1 5 1 3 9 9 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 KII86203.1 - 0.00011 21.9 13.4 3.2 7.6 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_16 PF13191.1 KII86203.1 - 0.00018 21.5 7.6 0.019 14.9 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain Foie-gras_1 PF11817.3 KII86203.1 - 0.00019 20.9 7.5 0.17 11.3 0.1 4.0 1 1 3 5 5 5 3 Foie gras liver health family 1 AAA_22 PF13401.1 KII86203.1 - 0.0011 19.1 0.0 0.0041 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KII86203.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SHNi-TPR PF10516.4 KII86203.1 - 0.0011 18.1 9.6 4 6.7 0.0 6.5 7 0 0 7 7 7 1 SHNi-TPR RPN7 PF10602.4 KII86203.1 - 0.0018 17.7 4.1 0.074 12.4 0.1 3.7 1 1 1 3 3 3 1 26S proteasome subunit RPN7 NRN1 PF15056.1 KII86203.1 - 0.003 17.4 9.4 12 5.9 0.0 6.3 5 2 2 7 7 7 0 Neuritin protein family NB-ARC PF00931.17 KII86203.1 - 0.0034 16.2 0.0 0.0074 15.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.1 KII86203.1 - 0.006 16.9 33.1 1.6 9.3 0.1 9.1 8 1 0 9 9 9 2 Tetratricopeptide repeat Sigma54_activat PF00158.21 KII86203.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TPR_4 PF07721.9 KII86203.1 - 0.041 14.3 7.7 17 6.1 0.0 6.1 8 0 0 8 8 4 0 Tetratricopeptide repeat DUF1713 PF08213.6 KII86203.1 - 0.042 13.4 1.4 0.067 12.8 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) TPR_8 PF13181.1 KII86203.1 - 0.064 13.0 20.3 4.7 7.2 0.1 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat Semialdhyde_dhC PF02774.13 KII86203.1 - 0.096 12.5 0.3 7.9 6.2 0.0 3.3 3 2 1 4 4 3 0 Semialdehyde dehydrogenase, dimerisation domain DUF4398 PF14346.1 KII86203.1 - 0.26 11.3 28.0 1e+02 3.0 0.1 7.0 3 1 2 5 5 4 0 Domain of unknown function (DUF4398) TPR_7 PF13176.1 KII86203.1 - 0.56 10.1 19.2 39 4.3 0.0 7.6 8 1 0 8 8 7 0 Tetratricopeptide repeat DASH_Spc19 PF08287.6 KII86205.1 - 0.032 13.8 0.3 0.087 12.4 0.2 1.5 1 1 0 1 1 1 0 Spc19 MAD PF05557.8 KII86205.1 - 0.063 11.3 0.1 0.08 11.0 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Prefoldin_3 PF13758.1 KII86205.1 - 0.15 11.8 1.0 0.22 11.2 0.7 1.3 1 0 0 1 1 1 0 Prefoldin subunit Fib_alpha PF08702.5 KII86205.1 - 0.21 11.6 0.3 0.31 11.1 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Thymopoietin PF08198.6 KII86206.1 - 1.2 8.7 4.8 35 4.0 0.0 4.2 3 2 2 5 5 5 0 Thymopoietin protein TPR_12 PF13424.1 KII86211.1 - 3.5e-43 145.4 34.5 8.9e-10 38.3 1.3 6.1 2 1 1 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 KII86211.1 - 1.8e-32 108.5 34.3 0.0094 15.8 0.1 10.7 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_16 PF13432.1 KII86211.1 - 1e-24 86.5 28.9 1.8e-06 28.4 0.3 9.3 2 2 5 8 8 8 7 Tetratricopeptide repeat SNAP PF14938.1 KII86211.1 - 1.5e-23 83.3 20.5 1.5e-11 43.9 0.7 3.7 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KII86211.1 - 1.4e-20 72.7 30.2 5.3e-05 22.7 0.8 8.2 5 3 2 7 7 6 6 TPR repeat TPR_10 PF13374.1 KII86211.1 - 2.7e-19 68.4 42.4 0.048 13.6 0.2 10.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 KII86211.1 - 1.7e-14 52.7 30.8 0.33 10.6 0.0 10.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 KII86211.1 - 5.8e-09 35.4 22.7 11 6.4 0.0 10.7 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII86211.1 - 4.2e-08 33.4 43.8 0.074 13.4 1.5 7.9 4 1 5 9 9 8 6 Tetratricopeptide repeat AAA_16 PF13191.1 KII86211.1 - 9e-08 32.3 10.7 0.026 14.5 0.0 5.4 3 2 1 4 4 4 3 AAA ATPase domain Apc3 PF12895.2 KII86211.1 - 1.1e-07 31.9 26.4 0.047 13.8 1.2 6.2 2 2 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KII86211.1 - 1.3e-06 28.4 25.2 16 6.5 0.0 10.2 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_21 PF09976.4 KII86211.1 - 1.1e-05 25.4 29.4 0.1 12.5 2.4 5.7 1 1 6 7 7 7 7 Tetratricopeptide repeat SHNi-TPR PF10516.4 KII86211.1 - 3e-05 23.1 21.1 5.6 6.2 0.1 9.1 9 0 0 9 9 9 0 SHNi-TPR NB-ARC PF00931.17 KII86211.1 - 0.00028 19.8 0.0 0.013 14.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain SMC_hinge PF06470.8 KII86211.1 - 0.00064 19.6 5.3 1.1 9.1 0.1 5.5 1 1 4 7 7 7 1 SMC proteins Flexible Hinge Domain AAA_22 PF13401.1 KII86211.1 - 0.0018 18.4 0.0 0.015 15.4 0.0 2.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KII86211.1 - 0.0025 17.4 0.6 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.9 KII86211.1 - 0.0031 16.5 0.0 1.4 7.8 0.0 2.6 2 0 0 2 2 2 1 KAP family P-loop domain SAM_adeno_trans PF01887.11 KII86211.1 - 0.004 16.2 0.0 2.8 6.9 0.0 2.5 2 0 0 2 2 2 2 S-adenosyl-l-methionine hydroxide adenosyltransferase AAA_24 PF13479.1 KII86211.1 - 0.0081 15.7 0.3 1.9 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Ldh_1_N PF00056.18 KII86211.1 - 0.012 15.3 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain TPR_4 PF07721.9 KII86211.1 - 0.022 15.1 9.8 44 4.9 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat tRNA_m1G_MT PF01746.16 KII86211.1 - 0.025 14.1 0.1 74 2.8 0.0 4.7 4 2 2 6 6 6 0 tRNA (Guanine-1)-methyltransferase DUF1713 PF08213.6 KII86211.1 - 0.079 12.5 0.8 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) TPR_7 PF13176.1 KII86211.1 - 0.079 12.7 29.0 22 5.1 0.0 9.8 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_3 PF07720.7 KII86211.1 - 0.2 11.4 20.4 12 5.7 0.0 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF3497 PF12003.3 KII86211.1 - 0.33 10.2 2.9 39 3.5 0.1 4.0 2 1 0 3 3 3 0 Domain of unknown function (DUF3497) Tho2 PF11262.3 KII86211.1 - 0.47 9.4 3.1 16 4.4 0.0 3.9 3 2 2 5 5 5 0 Transcription factor/nuclear export subunit protein 2 NRN1 PF15056.1 KII86211.1 - 0.52 10.3 18.2 35 4.4 0.1 8.0 4 3 4 9 9 9 0 Neuritin protein family ABC_tran PF00005.22 KII86211.1 - 0.88 9.8 4.1 11 6.3 0.1 3.4 3 0 0 3 3 2 0 ABC transporter TPR_6 PF13174.1 KII86211.1 - 3.7 8.2 44.0 16 6.2 0.2 10.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 KII86211.1 - 6.4 6.8 25.1 47 4.0 0.1 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat F-box-like PF12937.2 KII86213.1 - 0.0082 15.8 0.6 0.024 14.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII86214.1 - 0.02 14.6 1.2 0.15 11.8 0.8 2.7 1 0 0 1 1 1 0 F-box-like Epimerase PF01370.16 KII86215.1 - 6.8e-22 78.0 0.0 8.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII86215.1 - 4.4e-15 55.1 0.0 7e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII86215.1 - 8.7e-14 51.9 0.1 1.8e-13 50.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII86215.1 - 1.2e-08 34.1 0.1 2.7e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII86215.1 - 6.6e-07 28.8 0.2 9e-07 28.3 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KII86215.1 - 0.00053 19.9 0.1 0.0034 17.3 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KII86217.1 - 7.1e-21 74.7 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII86217.1 - 1.2e-11 45.0 0.4 2.3e-11 44.0 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII86217.1 - 1.7e-11 43.5 0.5 2.7e-10 39.5 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KII86217.1 - 7.3e-11 41.2 0.1 1.3e-10 40.4 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KII86217.1 - 4e-06 26.2 0.3 5.7e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KII86217.1 - 0.00024 21.0 2.5 0.0011 18.8 0.6 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII86217.1 - 0.0051 16.5 0.7 0.11 12.1 0.5 2.4 1 1 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 KII86217.1 - 0.08 12.9 0.1 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF3133 PF11331.3 KII86218.1 - 0.017 14.6 2.5 4.3 6.9 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) PilJ PF13675.1 KII86219.1 - 0.084 13.2 2.2 0.22 11.8 0.2 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term NOD PF06816.8 KII86219.1 - 0.13 11.3 0.4 0.26 10.3 0.2 1.5 1 0 0 1 1 1 0 NOTCH protein F-box PF00646.28 KII86220.1 - 0.00014 21.4 1.7 0.00032 20.2 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII86220.1 - 0.13 12.0 2.2 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KII86222.1 - 0.00066 19.2 0.1 0.00066 19.2 0.1 3.1 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.2 KII86222.1 - 0.0009 18.9 0.1 0.0009 18.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII86223.1 - 4.6e-06 26.2 0.1 1.2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like AMP-binding PF00501.23 KII86225.1 - 4.5e-87 292.1 0.0 5.5e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII86225.1 - 1.2e-12 48.5 1.2 3.3e-12 47.1 0.8 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.4 KII86226.1 - 2.6e-19 69.3 0.0 1.7e-18 66.7 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII86226.1 - 5.7e-07 30.1 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII86226.1 - 0.00021 20.6 0.0 0.00044 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KII86226.1 - 0.0012 18.8 0.0 0.0033 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII86226.1 - 0.0021 18.5 0.0 0.0055 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII86226.1 - 0.0072 15.9 0.0 0.024 14.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII86226.1 - 0.053 13.8 0.0 0.82 10.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KII86226.1 - 0.087 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 KII86227.1 - 6.1e-05 22.6 0.0 0.00017 21.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 KII86228.1 - 8.4e-37 126.6 28.0 8.4e-37 126.6 19.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII86228.1 - 4.2e-16 58.5 5.1 4.2e-16 58.5 3.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KII86228.1 - 0.0042 15.2 1.2 0.0087 14.1 0.8 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family YbgT_YccB PF08173.6 KII86228.1 - 0.0076 16.0 0.4 0.03 14.1 0.3 2.1 1 0 0 1 1 1 1 Membrane bound YbgT-like protein APH PF01636.18 KII86231.1 - 3.7e-15 56.3 0.3 5e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII86231.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KII86231.1 - 0.0025 16.8 0.1 0.21 10.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 KII86231.1 - 0.0042 16.0 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 KII86231.1 - 0.045 12.4 0.0 5.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Peptidase_C41 PF05417.6 KII86231.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease Pkinase PF00069.20 KII86233.1 - 5.2e-66 222.4 0.0 4.8e-36 124.2 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KII86233.1 - 6.7e-31 107.2 0.0 1.7e-14 53.5 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 KII86233.1 - 2.8e-23 82.4 0.3 2.3e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.17 KII86233.1 - 5.8e-18 64.8 0.3 2.2e-17 62.9 0.2 2.0 1 0 0 1 1 1 1 RWD domain Kdo PF06293.9 KII86233.1 - 0.00039 19.5 0.0 0.33 9.9 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII86233.1 - 0.00051 19.8 2.3 0.0009 19.0 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII86233.1 - 0.0019 17.2 0.0 0.0062 15.5 0.0 1.9 1 0 0 1 1 1 1 Kinase-like UPF0561 PF10573.4 KII86233.1 - 1.8 8.4 7.4 0.5 10.2 2.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 F-box-like PF12937.2 KII86234.1 - 0.00049 19.7 0.1 0.0015 18.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KII86234.1 - 0.0016 18.1 0.4 0.099 12.4 0.0 3.9 4 1 1 5 5 5 1 Leucine rich repeat F-box-like PF12937.2 KII86235.1 - 1.2e-06 28.0 1.4 7.6e-06 25.5 0.1 2.7 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 KII86236.1 - 1.4e-62 211.2 0.0 1.7e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86236.1 - 3.1e-28 98.5 0.0 4.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII86236.1 - 4.4e-06 25.8 0.0 8.3e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII86236.1 - 0.0089 15.7 0.0 0.035 13.8 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KII86236.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KII86236.1 - 0.085 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KII86236.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.7 KII86238.1 - 0.14 10.0 21.6 0.16 9.8 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 KII86238.1 - 0.24 9.9 9.4 0.28 9.7 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.1 KII86238.1 - 0.68 8.8 11.9 0.96 8.3 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPX PF03105.14 KII86238.1 - 1.2 8.8 11.3 1.6 8.4 7.8 1.2 1 0 0 1 1 1 0 SPX domain SGT1 PF07093.6 KII86238.1 - 1.6 7.0 14.7 2.2 6.5 10.2 1.2 1 0 0 1 1 1 0 SGT1 protein Spore_coat_CotO PF14153.1 KII86238.1 - 2.3 7.6 10.5 2.8 7.3 7.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.8 KII86238.1 - 3.1 7.5 17.7 4.5 7.0 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 KII86238.1 - 3.2 7.3 24.6 6.4 6.4 17.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase_Tyr PF07714.12 KII86240.1 - 5.7e-23 81.2 0.0 7.8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII86240.1 - 6.3e-13 48.4 0.0 1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PBP PF01161.15 KII86243.1 - 4.1e-25 88.3 0.0 4.8e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Alpha-amylase PF00128.19 KII86244.1 - 8.6e-21 74.6 0.0 2.4e-20 73.1 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KII86244.1 - 1.5e-09 37.8 0.0 4.6e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain adh_short PF00106.20 KII86246.1 - 2.8e-33 115.1 1.4 4.3e-33 114.5 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII86246.1 - 1.6e-25 90.2 1.0 4e-25 88.9 0.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII86246.1 - 1.1e-17 64.2 0.6 1.7e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KII86246.1 - 0.022 14.3 1.3 0.034 13.7 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KII86246.1 - 0.11 12.3 1.0 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain A_deaminase PF00962.17 KII86247.1 - 3.5e-24 85.3 0.0 4.8e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.15 KII86247.1 - 0.0045 16.7 0.1 0.0069 16.0 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF3752 PF12572.3 KII86248.1 - 2.3e-35 121.9 5.6 2.3e-35 121.9 3.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Cullin PF00888.17 KII86249.1 - 6.1e-107 358.5 0.5 8.6e-107 358.0 0.0 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KII86249.1 - 5e-24 83.9 3.5 8.9e-24 83.1 1.1 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain G-alpha PF00503.15 KII86250.1 - 1.5e-108 362.9 0.3 1.8e-108 362.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII86250.1 - 2.7e-11 43.0 6.6 1.8e-08 33.8 0.4 3.2 2 2 0 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 KII86250.1 - 0.00067 20.1 0.1 0.8 10.2 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KII86250.1 - 0.014 15.2 0.0 7.2 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SNF2_N PF00176.18 KII86250.1 - 0.039 12.7 0.1 0.063 12.0 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain GTP_EFTU PF00009.22 KII86250.1 - 0.042 13.2 0.2 8.2 5.8 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KII86250.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KII86250.1 - 0.14 11.2 5.9 1.5 7.9 0.3 2.6 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region WD40 PF00400.27 KII86251.1 - 2.6e-09 36.6 0.0 0.036 13.9 0.0 5.6 6 1 0 6 6 6 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KII86251.1 - 0.084 11.6 0.0 0.54 8.9 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region IKI3 PF04762.7 KII86251.1 - 0.15 9.8 0.0 2.9 5.5 0.0 2.0 2 0 0 2 2 2 0 IKI3 family SPO22 PF08631.5 KII86252.1 - 8.1e-20 71.0 4.4 2.9e-17 62.6 0.4 3.5 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.12 KII86252.1 - 0.033 14.0 1.0 11 6.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KII86252.1 - 2.2 8.4 7.0 2.8 8.1 0.0 4.1 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Cyclin PF08613.6 KII86254.1 - 3.2e-16 60.0 0.0 6e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KII86254.1 - 6.3e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Phi-29_GP4 PF05464.6 KII86254.1 - 0.093 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Peptidase_S10 PF00450.17 KII86255.1 - 2.5e-112 376.0 0.1 3.1e-112 375.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KII86255.1 - 4e-07 30.1 0.0 3.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chs3p PF12271.3 KII86256.1 - 1.4e-116 388.5 18.4 1.7e-116 388.3 12.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Ycf66_N PF07444.6 KII86256.1 - 3.3 7.5 7.4 3 7.6 0.4 2.8 2 1 0 2 2 2 0 Ycf66 protein N-terminus Methyltransf_22 PF13383.1 KII86257.1 - 2e-27 96.3 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KII86257.1 - 4.8e-08 33.1 0.0 6.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DHC_N1 PF08385.7 KII86258.1 - 2.7e-194 646.8 8.0 1.5e-193 644.3 0.3 2.6 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 PMC2NT PF08066.7 KII86258.1 - 0.2 11.9 2.0 11 6.4 0.0 3.3 3 1 0 3 3 3 0 PMC2NT (NUC016) domain Aminotran_4 PF01063.14 KII86259.1 - 4e-23 82.1 0.0 7e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV 2-oxoacid_dh PF00198.18 KII86261.1 - 5.9e-47 159.8 0.0 1.2e-46 158.8 0.0 1.5 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KII86261.1 - 1.2e-18 66.4 0.1 2.5e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KII86261.1 - 3.5e-13 48.9 0.8 7.5e-13 47.8 0.5 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KII86261.1 - 1.4e-05 24.6 0.1 0.0001 21.8 0.1 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 KII86261.1 - 0.085 13.2 0.1 0.39 11.0 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein adh_short PF00106.20 KII86262.1 - 3.1e-12 46.7 8.5 5e-10 39.5 2.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KII86262.1 - 4.8e-05 23.0 5.9 8.7e-05 22.2 1.1 2.2 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KII86262.1 - 0.00024 20.8 0.0 0.00073 19.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KII86262.1 - 0.0003 20.8 3.2 0.00054 20.0 0.4 2.3 1 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KII86262.1 - 0.0073 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 KII86262.1 - 0.03 14.0 0.5 0.099 12.3 0.3 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII86262.1 - 0.055 12.9 0.7 0.24 10.8 0.5 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KII86262.1 - 0.095 11.7 0.1 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NrfD PF03916.9 KII86262.1 - 0.11 11.9 1.7 0.2 11.0 1.2 1.5 1 0 0 1 1 1 0 Polysulphide reductase, NrfD 3HCDH_N PF02737.13 KII86262.1 - 0.15 11.7 0.3 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 KII86264.1 - 1.7e-59 201.5 0.0 2.2e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII86265.1 - 7.4e-71 239.0 0.0 8.3e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII86266.1 - 5.2e-70 236.2 0.0 5.9e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDKN3 PF05706.7 KII86267.1 - 9e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 KII86267.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KII86267.1 - 0.00019 21.0 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KII86267.1 - 0.028 14.6 0.2 0.31 11.2 0.2 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family Alpha-amylase PF00128.19 KII86268.1 - 1.1e-95 320.6 0.6 2.2e-94 316.4 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain PS_Dcarbxylase PF02666.10 KII86269.1 - 3e-73 245.4 0.0 4.7e-71 238.2 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Rtf2 PF04641.7 KII86270.1 - 5.3e-74 248.6 0.8 6.4e-74 248.4 0.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KII86270.1 - 0.00021 20.7 0.5 0.03 13.8 0.0 2.5 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KII86270.1 - 0.027 14.1 0.1 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 KII86270.1 - 0.13 12.1 0.3 0.65 9.8 0.3 2.1 1 1 1 2 2 2 0 Ring finger domain Med21 PF11221.3 KII86271.1 - 4.2e-28 98.1 6.1 4.9e-28 97.9 4.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Cep57_MT_bd PF06657.8 KII86271.1 - 0.019 14.9 10.4 0.039 13.9 1.2 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Synaptobrevin PF00957.16 KII86271.1 - 0.033 13.7 1.1 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF3391 PF11871.3 KII86271.1 - 0.45 10.7 4.7 1.6 8.9 3.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1192 PF06698.6 KII86271.1 - 0.52 10.1 2.6 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cortex-I_coil PF09304.5 KII86271.1 - 0.7 9.9 4.3 0.79 9.7 1.4 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil ChaC PF04752.7 KII86273.1 - 9.8e-50 168.9 0.0 1.1e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 KII86273.1 - 0.0051 17.2 0.0 0.0072 16.7 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DUF4038 PF13204.1 KII86273.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4038) DUF21 PF01595.15 KII86274.1 - 3.6e-28 98.1 0.1 5.6e-28 97.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KII86274.1 - 2.5e-10 39.9 0.2 0.0001 22.0 0.0 3.0 3 0 0 3 3 3 2 CBS domain tRNA_U5-meth_tr PF05958.6 KII86275.1 - 3e-12 45.9 0.0 4e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KII86275.1 - 4.3e-08 32.8 0.0 7.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KII86275.1 - 5.7e-07 29.2 0.0 9.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KII86275.1 - 2.2e-06 27.7 0.0 5.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86275.1 - 0.00065 20.2 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII86275.1 - 0.0016 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII86275.1 - 0.0022 17.4 0.0 0.0079 15.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.11 KII86275.1 - 0.0057 16.2 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 KII86275.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KII86275.1 - 0.023 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 KII86275.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.15 KII86276.1 - 5.2e-34 117.8 0.0 1.8e-32 112.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII86276.1 - 9.1e-11 42.0 1.9 2.4e-10 40.7 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KII86276.1 - 0.0059 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.15 KII86276.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase F-box-like PF12937.2 KII86278.1 - 1.2e-07 31.3 1.0 1.2e-07 31.3 0.7 2.2 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 KII86279.1 - 7.1e-18 64.0 3.5 9.5e-14 50.8 1.6 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KII86279.1 - 8.1e-14 50.5 7.2 4.6e-05 22.8 0.9 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII86279.1 - 3.1e-11 42.2 6.9 0.00015 21.4 0.9 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KII86279.1 - 1.3e-07 31.4 0.3 0.0029 17.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII86279.1 - 1.1e-06 27.9 6.2 0.22 11.3 1.5 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII86279.1 - 1.2e-06 28.7 3.4 0.00011 22.5 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII86279.1 - 4.3e-06 27.2 2.1 0.017 15.7 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KII86279.1 - 3.5e-05 23.8 1.2 6.2e-05 23.0 0.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KII86279.1 - 3.7e-05 23.9 0.5 0.14 12.9 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII86279.1 - 0.0004 20.6 4.5 1.5 9.4 0.1 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat GlutR_N PF05201.10 KII86279.1 - 0.00043 19.8 0.3 0.00057 19.5 0.2 1.3 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain TPR_17 PF13431.1 KII86279.1 - 0.0025 17.8 1.4 0.49 10.7 0.0 3.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KII86279.1 - 0.0049 16.8 2.5 0.43 10.5 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KII86279.1 - 0.025 14.4 1.1 3.2 7.6 0.0 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.1 KII86279.1 - 0.027 14.5 1.5 0.027 14.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_7 PF13176.1 KII86279.1 - 0.037 13.8 1.8 4.6 7.2 0.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat EzrA PF06160.7 KII86279.1 - 0.062 11.4 0.8 0.084 11.0 0.6 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SNAP PF14938.1 KII86279.1 - 2.5 7.1 10.9 5.2 6.1 7.6 1.7 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Peptidase_C14 PF00656.17 KII86280.1 - 2.9e-61 207.3 0.0 4.7e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Psu PF07455.6 KII86280.1 - 0.17 11.3 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) tRNA-synt_1c PF00749.16 KII86282.1 - 6e-85 284.6 0.0 1e-84 283.9 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Alpha-amylase PF00128.19 KII86283.1 - 7e-68 229.3 0.1 9.1e-68 228.9 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KII86283.1 - 2e-12 47.0 0.5 3.8e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Chlorovi_GP_rpt PF06598.6 KII86283.1 - 1.1 9.2 3.8 8.9 6.2 0.3 2.9 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Cys_Met_Meta_PP PF01053.15 KII86285.1 - 6.4e-127 423.0 0.0 6.1e-126 419.7 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KII86285.1 - 0.005 15.8 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 KII86285.1 - 0.011 14.0 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase zf-UBR PF02207.15 KII86286.1 - 2.6e-15 55.9 16.0 2.6e-15 55.9 11.1 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KII86286.1 - 1.2e-11 44.1 0.2 3e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 KII86286.1 - 0.039 13.1 0.1 0.095 11.8 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL DNA_pol_phi PF04931.8 KII86286.1 - 0.79 7.4 4.9 1.1 6.8 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAPP PF04051.11 KII86287.1 - 3.6e-31 107.7 0.0 4.6e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Alpha-amylase PF00128.19 KII86288.1 - 5.2e-67 226.4 0.5 6.6e-67 226.1 0.4 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KII86288.1 - 3e-16 59.2 0.0 6.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 KII86288.1 - 0.11 11.4 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme SNF2_N PF00176.18 KII86289.1 - 5.8e-52 176.3 0.0 1e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII86289.1 - 4.1e-11 42.5 0.0 9.6e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII86289.1 - 8e-07 28.7 0.0 4.3e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KII86289.1 - 0.00024 20.9 0.0 0.0012 18.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glycophorin_A PF01102.13 KII86292.1 - 0.0098 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A Herpes_gE PF02480.11 KII86292.1 - 0.013 13.7 0.0 0.023 12.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2244 PF10003.4 KII86292.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PCI PF01399.22 KII86293.1 - 6e-08 32.9 1.0 1.7e-07 31.4 0.2 2.1 2 0 0 2 2 2 1 PCI domain Lectin_N PF03954.9 KII86293.1 - 0.056 12.8 1.2 0.12 11.8 0.8 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4404 PF14357.1 KII86293.1 - 0.12 12.8 2.8 0.13 12.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Glyco_transf_25 PF01755.12 KII86295.1 - 1.7e-08 34.3 0.0 9.7e-07 28.6 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) OPT PF03169.10 KII86297.1 - 3.9e-182 606.9 58.8 1.3e-180 601.9 40.8 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein AAA_17 PF13207.1 KII86298.1 - 2e-05 25.4 0.1 0.00012 22.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KII86298.1 - 0.00032 20.3 0.0 0.00062 19.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KII86298.1 - 0.00056 20.2 0.1 0.0029 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KII86298.1 - 0.0058 16.5 0.2 0.051 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII86298.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 KII86298.1 - 0.033 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein KTI12 PF08433.5 KII86298.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MFS_1 PF07690.11 KII86299.1 - 1.6e-29 102.7 29.8 2.4e-28 98.9 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3640 PF12342.3 KII86302.1 - 0.094 12.2 0.6 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) OPT PF03169.10 KII86303.1 - 3.1e-196 653.5 54.2 3.6e-196 653.3 37.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3142 PF11340.3 KII86304.1 - 0.002 17.8 0.3 0.0028 17.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF91 PF01939.11 KII86304.1 - 0.0072 15.4 1.1 0.013 14.7 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF91 Mt_ATP-synt_D PF05873.7 KII86304.1 - 0.0099 15.5 0.8 0.017 14.7 0.2 1.6 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF342 PF03961.8 KII86304.1 - 0.08 11.3 0.9 0.092 11.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF837 PF05769.6 KII86304.1 - 0.09 12.2 5.2 0.15 11.5 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF837) OmpH PF03938.9 KII86304.1 - 0.37 10.7 6.3 0.48 10.3 4.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.3 KII86304.1 - 4 6.6 14.6 11 5.2 4.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) zf-Apc11 PF12861.2 KII86305.1 - 3e-39 132.7 11.2 3.5e-39 132.5 7.8 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KII86305.1 - 3.2e-30 104.0 11.4 3.9e-30 103.7 7.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KII86305.1 - 2.4e-05 24.0 16.4 4.7e-05 23.1 10.6 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII86305.1 - 0.0082 16.1 5.2 0.0082 16.1 3.6 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII86305.1 - 0.041 13.6 13.8 0.75 9.5 10.1 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KII86305.1 - 0.13 11.9 13.6 0.63 9.7 9.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KII86305.1 - 0.28 10.7 3.8 0.47 10.0 2.7 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rgp1 PF08737.5 KII86306.1 - 1.2e-52 179.4 0.0 1.6e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 Rgp1 PSP1 PF04468.7 KII86307.1 - 3.9e-31 106.8 1.0 6.3e-31 106.2 0.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-C2H2 PF00096.21 KII86309.1 - 5.3e-07 29.6 13.3 0.0015 18.7 2.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII86309.1 - 2.2e-06 27.6 6.6 4e-05 23.6 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII86309.1 - 0.0027 17.9 8.9 0.33 11.3 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-CHY PF05495.7 KII86309.1 - 0.24 11.5 3.4 0.42 10.7 2.3 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 KII86309.1 - 6 6.6 8.6 1.5 8.5 2.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Herpes_LMP2 PF07415.6 KII86310.1 - 0.4 9.2 0.2 0.62 8.5 0.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein F-box-like PF12937.2 KII86311.1 - 2e-05 24.1 0.1 4e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 F-box-like Glyco_hydro_16 PF00722.16 KII86313.1 - 1.4e-06 27.6 0.0 2.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Bromodomain PF00439.20 KII86314.1 - 3.5e-21 74.9 0.0 1.5e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KII86314.1 - 5.2e-07 29.4 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 BAH domain DUF1479 PF07350.7 KII86315.1 - 1.3e-131 438.9 0.0 1.4e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KII86315.1 - 0.0022 18.0 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Pro_dh PF01619.13 KII86316.1 - 5e-36 124.2 0.1 1.3e-16 60.4 0.0 3.6 1 1 0 2 2 2 2 Proline dehydrogenase p450 PF00067.17 KII86317.1 - 8.2e-55 186.1 0.0 1.9e-54 184.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF3415 PF11895.3 KII86318.1 - 1.9e-32 110.9 1.3 3.5e-32 110.0 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KII86318.1 - 1.1e-30 106.8 0.0 1.7e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase SprT-like PF10263.4 KII86319.1 - 9.2e-38 129.3 0.3 1.2e-37 128.9 0.2 1.2 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 KII86319.1 - 0.048 13.6 1.7 0.098 12.6 1.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain PUF PF00806.14 KII86320.1 - 1.7e-56 184.6 12.7 1.2e-07 30.7 0.1 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 KII86320.1 - 0.013 15.7 0.1 0.14 12.4 0.0 2.7 2 2 1 3 3 3 0 Protein of unknown function DUF260 DUF3436 PF11918.3 KII86320.1 - 0.092 12.9 0.0 0.32 11.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) Atg14 PF10186.4 KII86321.1 - 1.5e-14 53.6 0.0 2.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_S14 PF00253.16 KII86323.1 - 1.5e-17 62.6 3.5 1.6e-17 62.5 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Toxin_17 PF08086.6 KII86323.1 - 1.9 8.6 4.4 0.82 9.7 0.2 2.0 1 1 1 2 2 2 0 Ergtoxin family Glyco_trans_1_4 PF13692.1 KII86324.1 - 3.6e-21 75.7 0.1 2e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KII86324.1 - 3.3e-08 33.1 0.0 5.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KII86324.1 - 7.4e-05 22.9 0.3 0.00023 21.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KII86324.1 - 9.2e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Copper-fist PF00649.13 KII86326.1 - 6.7e-21 73.1 0.8 6.7e-21 73.1 0.5 2.6 2 0 0 2 2 2 1 Copper fist DNA binding domain F-box-like PF12937.2 KII86327.1 - 0.0011 18.6 2.1 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KII86327.1 - 0.0077 15.8 2.3 1.4 8.5 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) UQ_con PF00179.21 KII86328.1 - 1.2e-26 92.8 0.0 1.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII86328.1 - 7.4e-06 25.7 0.0 7.6e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B UEV PF05743.8 KII86328.1 - 0.0022 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KII86328.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.7 1 1 1 2 2 2 0 RWD domain Porphobil_deam PF01379.15 KII86329.1 - 1.1e-73 246.6 0.0 1.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KII86329.1 - 8.5e-17 61.0 1.4 1.6e-16 60.1 1.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CobN-Mg_chel PF02514.11 KII86329.1 - 0.0037 14.7 0.0 0.0062 14.0 0.0 1.2 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Nfu_N PF08712.6 KII86330.1 - 1.7e-30 104.4 0.0 4.6e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KII86330.1 - 2.5e-23 81.6 0.1 4e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain BAR PF03114.13 KII86333.1 - 2.3e-38 132.0 1.8 3.4e-38 131.4 1.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KII86333.1 - 1.3e-15 56.4 0.1 2.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KII86333.1 - 2e-15 56.0 0.1 3.3e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII86333.1 - 5.7e-10 38.5 0.0 1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KII86333.1 - 0.0015 17.7 0.6 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Vps5 C terminal like DUF605 PF04652.11 KII86333.1 - 2.7 7.2 11.8 4 6.7 8.2 1.2 1 0 0 1 1 1 0 Vta1 like SBDS_C PF09377.5 KII86334.1 - 1.9e-41 140.6 0.4 3.8e-41 139.7 0.3 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KII86334.1 - 8.9e-33 111.9 2.4 1.6e-32 111.1 1.7 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myc_N PF01056.13 KII86334.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region XkdN PF08890.6 KII86334.1 - 0.049 13.3 0.2 0.21 11.3 0.1 2.1 1 1 1 2 2 2 0 Phage XkdN-like protein BTB PF00651.26 KII86335.1 - 9.8e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1810 PF08837.6 KII86335.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) DUF3417 PF11897.3 KII86337.1 - 0.0046 16.9 0.4 0.044 13.7 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3417) F-box-like PF12937.2 KII86337.1 - 0.048 13.4 0.2 0.048 13.4 0.2 2.2 2 0 0 2 2 2 0 F-box-like Fe-S_biosyn PF01521.15 KII86338.1 - 2.1e-21 75.9 0.0 2.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SPRY PF00622.23 KII86341.1 - 4.5e-22 78.4 0.0 6.6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 KII86341.1 - 2.3e-14 53.3 0.0 3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KII86341.1 - 0.0062 16.2 0.1 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 LisH adh_short PF00106.20 KII86342.1 - 3.9e-26 91.9 1.2 7.6e-26 91.0 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII86342.1 - 3.6e-17 62.9 0.1 2e-16 60.5 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII86342.1 - 8.4e-12 45.1 0.5 1.3e-11 44.5 0.4 1.3 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII86342.1 - 0.017 14.8 0.4 0.42 10.4 0.0 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KII86342.1 - 0.022 14.1 0.1 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UMP1 PF05348.6 KII86343.1 - 4.3e-19 68.7 0.1 5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Cullin PF00888.17 KII86345.1 - 8.6e-07 27.8 0.0 1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family F-box-like PF12937.2 KII86350.1 - 1.5e-11 43.8 1.3 3.8e-11 42.5 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86350.1 - 0.028 14.0 1.3 0.77 9.4 0.9 2.8 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.2 KII86350.1 - 4.8 6.9 7.9 32 4.3 0.5 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DHO_dh PF01180.16 KII86351.1 - 3.2e-15 55.8 0.0 4.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.11 KII86352.1 - 3.3e-37 127.3 0.0 4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SET PF00856.23 KII86353.1 - 4.3e-07 30.3 0.0 1.6e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 SET domain HMG_box PF00505.14 KII86354.1 - 1.6e-14 53.9 0.0 3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII86354.1 - 1.9e-05 24.9 0.0 5.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 HMG-box domain PARP PF00644.15 KII86355.1 - 5.1e-57 192.6 0.0 5.1e-57 192.6 0.0 2.9 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KII86355.1 - 8.8e-35 119.2 0.0 1.3e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KII86355.1 - 1.1e-21 76.5 1.2 2.3e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 WGR domain TFIIE-A_C-term PF11521.3 KII86355.1 - 6.2 6.8 14.6 2.3 8.2 3.6 3.0 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Prp19_bind PF06991.6 KII86356.1 - 7.3e-62 209.1 40.7 2.4e-61 207.4 27.5 2.0 1 1 0 1 1 1 1 Splicing factor, Prp19-binding domain zf-CCHC_2 PF13696.1 KII86356.1 - 0.39 10.2 1.5 0.78 9.2 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 KII86356.1 - 0.39 10.7 4.0 1 9.4 2.8 1.7 1 1 0 1 1 1 0 Zinc knuckle RdRP PF05183.7 KII86357.1 - 1.2e-58 199.2 0.1 1.3e-58 199.1 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.7 KII86358.1 - 4.2e-73 246.9 0.0 5.7e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase BTV_NS2 PF04514.7 KII86358.1 - 0.022 13.6 2.0 0.03 13.2 1.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RXT2_N PF08595.6 KII86358.1 - 0.063 13.0 2.4 0.12 12.1 1.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 KII86358.1 - 0.13 11.8 4.0 0.2 11.1 2.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2722 PF10846.3 KII86358.1 - 0.17 10.8 1.2 0.26 10.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF688 PF05097.7 KII86358.1 - 1.1 8.0 3.8 0.76 8.6 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF688) DUF4611 PF15387.1 KII86358.1 - 2.1 8.5 6.9 4.2 7.5 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NAD_binding_8 PF13450.1 KII86359.1 - 4.8e-13 48.9 0.0 2e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII86359.1 - 0.0092 14.9 0.1 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII86359.1 - 0.014 15.1 0.1 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KII86359.1 - 0.08 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DNase_NucA_NucB PF14040.1 KII86360.1 - 5.1e-15 55.6 0.3 8.7e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF4234 PF14018.1 KII86361.1 - 0.0029 17.3 2.3 0.0029 17.3 1.6 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4234) RseC_MucC PF04246.7 KII86361.1 - 6.2 6.4 12.6 0.055 13.0 1.0 2.7 1 1 2 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ComA PF02679.10 KII86362.1 - 1.4e-74 250.2 0.0 1.6e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) NmrA PF05368.8 KII86363.1 - 9.3e-17 61.0 0.1 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII86363.1 - 0.00013 21.5 0.8 0.00034 20.1 0.3 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KII86363.1 - 0.00031 19.8 0.5 0.00043 19.3 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KII86363.1 - 0.00054 20.0 0.2 0.0014 18.7 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KII86363.1 - 0.0014 18.3 0.1 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.15 KII86363.1 - 0.011 15.6 0.9 0.087 12.7 0.5 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus CPSase_L_chain PF00289.17 KII86363.1 - 0.012 15.6 0.3 0.023 14.8 0.2 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ApbA PF02558.11 KII86363.1 - 0.017 14.5 0.2 0.062 12.7 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KII86363.1 - 0.039 13.7 0.3 0.076 12.8 0.1 1.6 2 0 0 2 2 2 0 ThiF family NAD_binding_3 PF03447.11 KII86363.1 - 0.049 14.0 0.6 0.091 13.1 0.4 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain KR PF08659.5 KII86363.1 - 0.075 12.6 3.4 0.19 11.3 2.3 1.6 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 KII86363.1 - 0.088 12.7 2.9 0.14 12.0 2.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.17 KII86363.1 - 0.1 13.0 0.6 0.17 12.4 0.4 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 KII86363.1 - 0.14 11.7 0.8 0.22 11.1 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KII86363.1 - 0.22 11.5 1.2 0.34 10.9 0.4 1.6 2 0 0 2 2 1 0 TrkA-N domain SNF2_N PF00176.18 KII86364.1 - 3.9e-82 275.4 0.5 3.9e-82 275.4 0.4 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KII86364.1 - 1e-21 76.6 0.2 2.9e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.8 KII86364.1 - 1.3e-14 53.7 9.6 1.3e-14 53.7 6.7 2.7 2 0 0 2 2 2 1 HSA Helicase_C PF00271.26 KII86364.1 - 1.4e-14 53.7 0.0 1.4e-14 53.7 0.0 3.3 5 0 0 5 5 5 1 Helicase conserved C-terminal domain SnAC PF14619.1 KII86364.1 - 4.1e-13 49.2 0.3 4.1e-13 49.2 0.2 4.0 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 KII86364.1 - 4.5e-11 41.9 0.1 1.5e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 QLQ DUF2784 PF10861.3 KII86365.1 - 0.008 15.9 1.6 0.009 15.7 1.1 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF2784) Ku PF02735.11 KII86366.1 - 9.5e-24 83.9 0.1 2e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 KII86366.1 - 1.4e-13 50.8 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 KII86366.1 - 3.9e-09 36.2 0.0 7.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 KII86366.1 - 2.7e-05 24.3 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KII86366.1 - 0.00033 20.4 0.0 0.00082 19.1 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain DNase_NucA_NucB PF14040.1 KII86367.1 - 1.4e-13 50.9 1.0 2.3e-13 50.3 0.7 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB NmrA PF05368.8 KII86369.1 - 5.4e-16 58.5 0.0 7e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KII86369.1 - 6.5e-05 22.0 0.1 8.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KII86369.1 - 0.00032 20.2 0.1 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_chain PF00289.17 KII86369.1 - 0.0039 17.2 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_10 PF13460.1 KII86369.1 - 0.0045 17.0 0.3 0.0068 16.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KII86369.1 - 0.0079 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KII86369.1 - 0.015 15.2 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KII86369.1 - 0.026 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KII86369.1 - 0.041 13.5 0.2 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KII86369.1 - 0.061 13.0 0.1 1 9.0 0.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RmlD_sub_bind PF04321.12 KII86369.1 - 0.07 12.0 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ThiF PF00899.16 KII86369.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 ThiF family NmrA PF05368.8 KII86370.1 - 5.5e-17 61.8 0.0 7.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII86370.1 - 0.00017 21.0 0.1 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KII86370.1 - 0.00031 20.7 0.6 0.11 12.4 0.1 2.4 2 0 0 2 2 2 2 TrkA-N domain Shikimate_DH PF01488.15 KII86370.1 - 0.0006 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KII86370.1 - 0.0012 17.8 0.3 0.0016 17.4 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 KII86370.1 - 0.019 14.6 0.3 0.038 13.6 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.15 KII86370.1 - 0.02 14.8 0.3 0.049 13.5 0.2 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.19 KII86370.1 - 0.055 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KII86370.1 - 0.056 13.9 0.1 0.093 13.2 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CPSase_L_chain PF00289.17 KII86370.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain CbiJ PF02571.9 KII86370.1 - 0.15 11.3 0.2 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NmrA PF05368.8 KII86371.1 - 6.1e-21 74.7 0.1 8.4e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII86371.1 - 0.00026 20.5 0.2 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KII86371.1 - 0.00048 19.2 0.6 0.00066 18.7 0.4 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KII86371.1 - 0.00053 20.0 0.1 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KII86371.1 - 0.0019 18.1 1.4 0.011 15.6 1.0 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CPSase_L_chain PF00289.17 KII86371.1 - 0.0081 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Gp_dh_N PF00044.19 KII86371.1 - 0.024 14.6 0.1 0.041 13.8 0.1 1.5 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KII86371.1 - 0.03 14.7 1.4 1.3 9.4 1.0 2.3 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KII86371.1 - 0.03 13.9 0.3 0.071 12.7 0.3 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 KII86371.1 - 0.049 13.5 1.0 0.082 12.8 0.7 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KII86371.1 - 0.056 12.3 0.1 0.089 11.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Aldolase PF01081.14 KII86371.1 - 0.099 11.7 0.3 0.16 11.1 0.2 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase GFO_IDH_MocA PF01408.17 KII86371.1 - 0.11 12.9 0.3 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.5 KII86371.1 - 0.13 11.8 1.1 0.42 10.2 0.7 1.7 1 1 0 1 1 1 0 KR domain TrkA_N PF02254.13 KII86371.1 - 0.16 11.9 0.4 0.32 10.9 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain Y_phosphatase PF00102.22 KII86372.1 - 4.8e-55 186.4 0.0 6.4e-47 159.8 0.0 2.7 2 1 0 2 2 2 2 Protein-tyrosine phosphatase NmrA PF05368.8 KII86372.1 - 5.3e-19 68.3 0.0 8.3e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Rhodanese PF00581.15 KII86372.1 - 4e-09 36.8 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Saccharop_dh PF03435.13 KII86372.1 - 7.1e-07 28.5 0.0 3.2e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase DSPc PF00782.15 KII86372.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KII86372.1 - 0.011 15.9 0.1 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CPSase_L_chain PF00289.17 KII86372.1 - 0.022 14.8 0.1 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Shikimate_DH PF01488.15 KII86372.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KII86372.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII86373.1 - 1.1e-19 70.5 0.0 2.8e-19 69.3 0.0 1.5 1 1 1 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 KII86373.1 - 0.017 14.1 1.8 0.034 13.1 0.2 2.1 1 1 1 2 2 2 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 KII86373.1 - 0.053 13.2 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 KII86373.1 - 0.12 11.7 0.1 0.3 10.4 0.1 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII86374.1 - 3.3e-12 46.1 0.0 5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KII86374.1 - 0.0001 21.4 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KII86374.1 - 0.0047 16.4 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_chain PF00289.17 KII86374.1 - 0.041 13.9 0.1 0.081 13.0 0.1 1.5 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_3 PF03447.11 KII86374.1 - 0.14 12.5 0.4 2.3 8.6 0.3 2.3 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.8 KII86375.1 - 6e-13 48.5 0.0 1.1e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII86375.1 - 0.0002 21.3 0.1 0.00035 20.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KII86375.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF883 PF05957.8 KII86376.1 - 0.065 13.6 5.8 0.04 14.3 2.5 1.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) SLY PF12485.3 KII86376.1 - 0.075 13.2 1.6 0.091 12.9 1.1 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein DivIVA PF05103.8 KII86376.1 - 0.62 10.1 4.0 0.83 9.7 2.7 1.3 1 1 0 1 1 1 0 DivIVA protein Tape_meas_lam_C PF09718.5 KII86376.1 - 0.86 9.5 3.8 2 8.3 0.2 2.4 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) EspB PF05802.6 KII86376.1 - 0.87 8.4 9.3 0.94 8.3 6.5 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein LHC PF00556.15 KII86377.1 - 1.7 8.5 7.5 0.35 10.7 1.5 2.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Las1 PF04031.8 KII86378.1 - 7.3e-47 158.8 0.1 1.2e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Las1-like DUF500 PF04366.7 KII86380.1 - 2.2e-35 120.8 0.2 3.7e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KII86380.1 - 6.3e-17 60.6 0.1 1.4e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KII86380.1 - 3.9e-16 58.3 0.3 1.7e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KII86380.1 - 3e-15 55.4 0.1 2.2e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain ABC_membrane PF00664.18 KII86381.1 - 1e-39 136.6 23.3 1.2e-26 93.7 3.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII86381.1 - 2.4e-38 131.5 0.0 2.4e-24 86.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII86381.1 - 3.6e-09 37.0 0.2 0.12 12.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_25 PF13481.1 KII86381.1 - 2.1e-07 30.5 0.4 0.031 13.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KII86381.1 - 2e-06 27.9 3.8 0.0017 18.3 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KII86381.1 - 1.6e-05 25.3 0.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KII86381.1 - 2.1e-05 23.8 4.1 0.23 10.6 0.0 4.1 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KII86381.1 - 0.00022 20.7 0.2 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KII86381.1 - 0.00064 18.6 0.0 0.25 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KII86381.1 - 0.00083 18.8 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KII86381.1 - 0.0011 19.7 0.0 2.2 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KII86381.1 - 0.0016 18.9 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KII86381.1 - 0.0048 16.8 1.1 0.4 10.6 0.1 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KII86381.1 - 0.0053 16.5 0.6 0.84 9.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 KII86381.1 - 0.0067 16.5 0.9 1.4 9.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 KII86381.1 - 0.013 14.1 0.1 0.083 11.5 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein MobB PF03205.9 KII86381.1 - 0.018 14.7 3.4 0.81 9.3 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B OB_RNB PF08206.6 KII86381.1 - 0.019 14.4 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF258 PF03193.11 KII86381.1 - 0.022 13.9 0.1 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 KII86381.1 - 0.024 14.4 1.2 0.14 11.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 KII86381.1 - 0.031 14.0 1.3 7.2 6.3 0.0 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KII86381.1 - 0.032 13.3 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 KII86381.1 - 0.045 13.2 0.1 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 KII86381.1 - 0.051 13.8 0.0 15 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KII86381.1 - 0.064 12.6 0.0 12 5.2 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KII86381.1 - 0.07 12.8 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 KII86381.1 - 0.072 12.5 1.3 26 4.2 0.0 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_10 PF12846.2 KII86381.1 - 0.088 12.2 0.3 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 KII86381.1 - 0.089 12.9 1.5 0.32 11.2 0.1 2.7 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KII86381.1 - 0.17 12.0 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DLH PF01738.13 KII86382.1 - 3.5e-12 46.0 0.0 4.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII86382.1 - 0.00019 21.1 0.0 0.00043 20.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Prenylcys_lyase PF07156.9 KII86384.1 - 1.1e-44 152.8 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.19 KII86384.1 - 5.5e-11 42.1 0.1 3.1e-10 39.7 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII86384.1 - 5.2e-10 39.2 0.1 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII86384.1 - 1.2e-05 25.4 0.0 0.014 15.4 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII86384.1 - 0.00041 19.3 1.6 0.054 12.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII86384.1 - 0.0018 18.0 0.2 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KII86384.1 - 0.015 15.1 0.3 0.73 9.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PsaN PF05479.6 KII86384.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) HI0933_like PF03486.9 KII86384.1 - 0.2 10.1 0.6 7.2 4.9 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Ammonium_transp PF00909.16 KII86385.1 - 2.2e-110 368.8 26.5 2.5e-110 368.6 18.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Colicin PF01024.14 KII86385.1 - 0.056 13.0 1.5 0.093 12.2 0.1 1.8 1 1 0 1 1 1 0 Colicin pore forming domain DUF2207 PF09972.4 KII86385.1 - 3.9 5.9 4.8 0.84 8.1 0.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NAD_binding_10 PF13460.1 KII86386.1 - 6.6e-26 91.4 1.9 8e-26 91.1 1.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII86386.1 - 2.8e-12 46.3 0.1 3.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII86386.1 - 7.6e-07 28.8 0.1 1.8e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KII86386.1 - 8.1e-07 28.3 0.1 1.1e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KII86386.1 - 0.00061 18.5 0.0 0.00086 18.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KII86386.1 - 0.00063 20.1 0.2 0.0021 18.4 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KII86386.1 - 0.0044 17.0 0.2 0.01 15.8 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 KII86386.1 - 0.0048 16.8 3.4 0.0071 16.2 2.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 KII86386.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ATP11 PF06644.6 KII86387.1 - 1.2e-66 224.9 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein SKG6 PF08693.5 KII86388.1 - 6.1e-05 22.2 2.8 0.00017 20.7 2.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KII86388.1 - 0.014 14.9 1.0 0.014 14.9 0.7 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 BPL_LplA_LipB PF03099.14 KII86389.1 - 1.9e-09 37.5 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Asp PF00026.18 KII86390.1 - 1.3e-46 159.3 11.7 3.5e-46 157.9 8.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII86390.1 - 0.0021 18.4 2.3 0.43 11.1 0.2 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KII86390.1 - 0.0087 16.0 0.5 0.094 12.6 0.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KII86390.1 - 0.0095 15.4 1.2 0.019 14.5 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KII86390.1 - 0.068 13.0 0.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease p450 PF00067.17 KII86392.1 - 1.5e-53 181.9 0.0 1.7e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 KII86393.1 - 7.5e-25 88.0 0.7 8.5e-25 87.8 0.5 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII86393.1 - 4.4e-13 49.0 0.1 5.8e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII86393.1 - 5.5e-08 32.5 0.1 1.4e-07 31.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII86393.1 - 3.6e-05 22.6 0.0 5e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KII86393.1 - 0.00017 21.5 1.6 0.00024 21.0 0.8 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 KII86393.1 - 0.00024 20.1 0.2 0.00031 19.8 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KII86393.1 - 0.0048 17.2 0.9 0.027 14.9 0.6 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KII86393.1 - 0.0073 15.9 0.3 0.042 13.4 0.3 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_2 PF03446.10 KII86393.1 - 0.0078 16.0 0.1 0.013 15.3 0.1 1.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 KII86393.1 - 0.016 14.7 1.4 0.037 13.5 0.5 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII86393.1 - 0.018 15.0 0.2 0.031 14.2 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 KII86393.1 - 0.097 11.5 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TauD PF02668.11 KII86394.1 - 3.3e-48 164.6 0.0 4.2e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.27 KII86395.1 - 8.3e-40 133.2 8.5 3.5e-09 36.1 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KII86395.1 - 1.4e-08 33.3 0.1 0.00078 17.7 0.0 3.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 IncA PF04156.9 KII86395.1 - 0.012 15.2 5.7 0.02 14.4 3.9 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KII86395.1 - 0.19 12.0 1.5 0.38 11.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KII86395.1 - 0.42 10.1 2.9 1.8 8.1 1.7 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 KII86395.1 - 7.9 5.4 7.2 12 4.7 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HNH_2 PF13391.1 KII86397.1 - 0.0098 15.6 0.2 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease BC10 PF06726.7 KII86400.1 - 1.5e-08 34.5 14.0 1.5e-08 34.5 9.7 1.8 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 CS PF04969.11 KII86401.1 - 1.8e-08 34.8 0.3 3.5e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 CS domain Fork_head_N PF08430.7 KII86401.1 - 1.2 9.5 14.3 1.8 8.9 9.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region F-box-like PF12937.2 KII86403.1 - 2.5e-10 39.9 0.5 8.5e-10 38.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII86403.1 - 5.8 6.6 7.3 12 5.7 1.7 3.5 2 1 1 3 3 3 0 F-box domain HAD_2 PF13419.1 KII86404.1 - 2.5e-18 66.9 0.0 3.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII86404.1 - 3.9e-11 42.4 0.1 1.3e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KII86404.1 - 0.00027 21.4 0.0 0.00042 20.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Toxin_1 PF00087.16 KII86405.1 - 0.033 14.5 1.5 0.083 13.2 1.0 1.7 1 0 0 1 1 1 0 Snake toxin DUF4399 PF14347.1 KII86405.1 - 0.047 13.7 0.2 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Ebola_NP PF05505.7 KII86406.1 - 1 7.3 4.1 7.8 4.4 0.5 2.0 2 0 0 2 2 2 0 Ebola nucleoprotein HNH_2 PF13391.1 KII86407.1 - 0.014 15.1 0.1 0.88 9.3 0.0 2.7 2 1 0 2 2 2 0 HNH endonuclease ABC_membrane PF00664.18 KII86412.1 - 2.4e-44 151.8 26.6 6.1e-23 81.6 4.8 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII86412.1 - 7.7e-35 120.1 0.0 3.6e-18 66.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII86412.1 - 3.1e-08 33.9 0.4 0.027 14.4 0.0 3.7 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 KII86412.1 - 5.6e-08 32.4 0.0 0.0019 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KII86412.1 - 3.5e-06 26.4 0.4 0.41 9.8 0.0 3.6 4 0 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KII86412.1 - 3.5e-06 27.1 0.4 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KII86412.1 - 4e-05 22.6 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 KII86412.1 - 4.2e-05 23.9 3.5 0.001 19.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KII86412.1 - 6.8e-05 22.3 0.1 0.3 10.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KII86412.1 - 0.00035 21.3 1.6 1.1 10.1 0.0 3.6 2 1 0 3 3 3 1 AAA domain Miro PF08477.8 KII86412.1 - 0.00036 21.0 0.0 1 9.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 KII86412.1 - 0.00089 19.0 0.0 0.055 13.1 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 KII86412.1 - 0.0012 18.7 0.1 0.57 10.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KII86412.1 - 0.0012 18.3 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 KII86412.1 - 0.0019 17.4 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 KII86412.1 - 0.0021 17.7 2.1 0.84 9.3 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KII86412.1 - 0.003 17.1 0.1 0.92 8.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 KII86412.1 - 0.0047 17.0 0.0 0.54 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KII86412.1 - 0.0071 16.1 0.5 0.095 12.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 KII86412.1 - 0.0072 15.0 0.0 0.052 12.1 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein Dynamin_N PF00350.18 KII86412.1 - 0.013 15.3 0.6 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 KII86412.1 - 0.013 14.6 0.1 1.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 KII86412.1 - 0.015 14.7 0.2 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KII86412.1 - 0.024 14.9 0.0 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KII86412.1 - 0.031 14.4 0.1 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KII86412.1 - 0.033 13.6 0.2 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KII86412.1 - 0.033 13.9 0.1 5 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KII86412.1 - 0.04 13.3 0.0 8.3 5.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KII86412.1 - 0.18 11.9 0.1 9.3 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KII86412.1 - 0.32 10.6 1.1 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 NACHT domain DUF3512 PF12024.3 KII86413.1 - 0.087 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.11 KII86414.1 - 2.3e-08 33.6 0.5 3.6e-08 33.0 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF515 PF04415.7 KII86415.1 - 3.9 5.5 5.4 9.4 4.3 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Romo1 PF10247.4 KII86416.1 - 5e-23 81.0 6.9 6.9e-23 80.6 4.8 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 KII86416.1 - 0.042 13.4 0.2 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 Glycine zipper Pex2_Pex12 PF04757.9 KII86417.1 - 5.9e-28 97.8 3.3 2.4e-27 95.8 2.3 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 KII86417.1 - 2.5e-09 36.6 6.6 3.4e-09 36.2 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII86417.1 - 2.2e-08 33.8 11.0 3.7e-08 33.0 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII86417.1 - 2.7e-08 33.6 10.5 4.2e-08 33.0 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII86417.1 - 5.3e-08 32.3 9.0 8e-08 31.8 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII86417.1 - 1.1e-06 28.2 9.2 1.6e-06 27.7 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII86417.1 - 0.0046 16.8 9.7 0.0086 15.9 6.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KII86417.1 - 0.0059 16.6 8.2 0.016 15.2 5.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KII86417.1 - 0.0087 15.8 1.7 0.015 15.0 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 KII86417.1 - 0.018 14.9 3.1 0.03 14.2 2.2 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_UBOX PF13445.1 KII86417.1 - 0.019 14.6 2.3 0.019 14.6 1.6 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KII86417.1 - 0.23 11.2 5.2 0.42 10.4 3.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KII86417.1 - 0.37 10.4 8.6 0.58 9.7 6.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KII86417.1 - 0.93 9.4 7.2 2.2 8.2 5.0 1.6 1 0 0 1 1 1 0 IBR domain LSM PF01423.17 KII86418.1 - 1.4e-13 50.1 0.7 1.8e-13 49.7 0.5 1.2 1 0 0 1 1 1 1 LSM domain DHC_N2 PF08393.8 KII86419.1 - 9.9e-131 435.9 9.3 9.9e-131 435.9 6.5 2.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KII86419.1 - 3.3e-124 415.5 0.1 1.3e-123 413.5 0.0 1.9 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KII86419.1 - 5.6e-77 258.3 0.0 3.2e-76 255.8 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KII86419.1 - 4.3e-45 153.3 0.0 1.3e-44 151.7 0.0 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KII86419.1 - 8.6e-45 152.7 0.3 1.5e-43 148.6 0.2 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KII86419.1 - 7.3e-39 133.4 3.9 1.2e-38 132.7 2.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KII86419.1 - 1.3e-29 102.6 0.2 1.6e-12 47.3 0.0 6.7 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KII86419.1 - 3.7e-21 75.4 0.0 3.6e-20 72.1 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 KII86419.1 - 3e-13 50.0 0.0 0.00099 19.3 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII86419.1 - 1.4e-12 47.8 0.0 0.022 14.8 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 KII86419.1 - 4.2e-10 39.6 0.2 0.25 11.1 0.0 5.7 5 0 0 5 5 5 3 AAA domain AAA_17 PF13207.1 KII86419.1 - 5.4e-08 33.6 0.1 0.1 13.4 0.0 6.0 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.1 KII86419.1 - 6.2e-08 32.8 4.8 0.1 12.5 0.0 6.1 7 0 0 7 7 5 2 AAA ATPase domain AAA_18 PF13238.1 KII86419.1 - 7.9e-08 32.6 3.4 0.011 15.9 0.0 6.3 6 0 0 6 6 6 1 AAA domain AAA_19 PF13245.1 KII86419.1 - 1.1e-06 28.2 0.0 0.81 9.4 0.0 4.7 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 KII86419.1 - 5.2e-06 26.3 0.0 0.59 10.0 0.0 5.3 6 0 0 6 6 5 2 AAA domain T2SE PF00437.15 KII86419.1 - 9.1e-06 24.7 0.0 0.058 12.2 0.0 3.6 4 0 0 4 4 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KII86419.1 - 1.1e-05 24.9 0.0 0.91 8.9 0.0 4.2 4 0 0 4 4 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KII86419.1 - 0.00017 21.0 0.8 0.34 10.3 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KII86419.1 - 0.00038 19.6 4.4 0.46 9.6 0.0 3.7 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KII86419.1 - 0.00071 19.0 0.0 0.67 9.5 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KII86419.1 - 0.0014 17.7 0.0 2.2 7.3 0.0 4.4 4 0 0 4 4 4 1 Zeta toxin AAA_25 PF13481.1 KII86419.1 - 0.0018 17.7 0.2 1.7 7.9 0.0 4.0 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 KII86419.1 - 0.0075 16.4 0.0 36 4.5 0.0 4.5 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.22 KII86419.1 - 0.0081 16.4 2.6 8.6 6.6 0.0 4.8 5 0 0 5 5 4 0 ABC transporter ResIII PF04851.10 KII86419.1 - 0.009 15.8 0.1 2.7 7.8 0.0 3.8 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KII86419.1 - 0.025 14.1 5.0 3.3 7.2 0.0 4.3 5 0 0 5 5 5 0 AAA domain PduV-EutP PF10662.4 KII86419.1 - 0.028 13.9 0.7 7 6.1 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KII86419.1 - 0.064 12.9 0.2 23 4.6 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B IFT46_B_C PF12317.3 KII86419.1 - 0.37 10.1 11.1 0.86 8.9 0.1 3.5 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal AAA_10 PF12846.2 KII86419.1 - 0.95 8.8 5.6 7.7 5.8 0.2 4.1 4 0 0 4 4 4 0 AAA-like domain PLRV_ORF5 PF01690.12 KII86419.1 - 7.4 5.5 4.5 13 4.8 3.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Dynein_heavy PF03028.10 KII86420.1 - 3.3e-36 124.6 0.0 3.9e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor GHMP_kinases_N PF00288.21 KII86422.1 - 1.7e-10 40.7 0.1 3.4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KII86422.1 - 0.005 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Metallothio_Cad PF07846.6 KII86425.1 - 0.0088 15.9 0.2 6.9 6.6 0.0 2.5 2 0 0 2 2 2 2 Metallothionein family LRR_4 PF12799.2 KII86426.1 - 0.015 14.9 2.7 5.1 6.8 0.1 3.8 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) HNH_2 PF13391.1 KII86427.1 - 0.012 15.4 0.1 0.032 14.0 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease Beta-lactamase PF00144.19 KII86430.1 - 9.3e-45 153.0 4.3 2.2e-44 151.8 1.3 2.2 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 KII86430.1 - 0.00036 20.3 0.2 0.0052 16.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Mg_trans_NIPA PF05653.9 KII86431.1 - 1e-23 83.7 8.6 1.6e-11 43.7 0.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KII86431.1 - 0.013 15.4 5.8 0.013 15.4 4.0 3.4 3 1 0 3 3 3 0 EamA-like transporter family DENN PF02141.16 KII86432.1 - 7.6e-20 71.4 0.0 1.4e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain ADIP PF11559.3 KII86432.1 - 0.016 15.0 8.3 0.034 14.0 5.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.9 KII86432.1 - 0.032 14.1 13.3 0.058 13.3 9.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.5 KII86432.1 - 0.061 13.5 5.6 0.18 11.9 3.9 1.8 1 0 0 1 1 1 0 Tup N-terminal APG6 PF04111.7 KII86432.1 - 0.15 11.0 6.2 0.25 10.3 4.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4196 PF13846.1 KII86432.1 - 0.15 12.3 4.8 0.56 10.5 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4196) GAS PF13851.1 KII86432.1 - 0.17 11.0 9.0 0.31 10.2 6.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MalF_P2 PF14785.1 KII86432.1 - 0.27 11.0 3.4 0.48 10.2 2.3 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain DUF342 PF03961.8 KII86432.1 - 0.55 8.5 4.2 0.88 7.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KII86432.1 - 0.59 9.6 6.8 1.5 8.4 4.7 1.7 1 0 0 1 1 1 0 IncA protein U1snRNP70_N PF12220.3 KII86432.1 - 0.8 10.0 3.8 2.7 8.3 2.6 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Spc24 PF08286.6 KII86432.1 - 3.8 7.2 6.8 3 7.5 2.3 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 KII86432.1 - 5.8 7.3 10.5 15 5.9 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF972) MbeD_MobD PF04899.7 KII86432.1 - 9.4 6.2 14.1 18 5.3 0.1 3.4 2 1 1 3 3 3 0 MbeD/MobD like HyaE PF07449.6 KII86433.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF1180 PF06679.7 KII86434.1 - 0.058 13.2 22.6 0.03 14.2 4.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) SseC PF04888.7 KII86434.1 - 0.25 10.6 6.1 1.9 7.7 0.1 2.3 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family DUF1162 PF06650.7 KII86435.1 - 2.6e-60 204.0 0.0 5.1e-57 193.1 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KII86435.1 - 6.4e-32 109.5 0.4 3.8e-31 107.0 0.1 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KII86435.1 - 3.5e-06 27.0 0.0 9.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain ELO PF01151.13 KII86437.1 - 5.4e-59 199.4 13.8 6.5e-59 199.2 9.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RasGAP PF00616.14 KII86438.1 - 1e-35 123.1 0.0 2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KII86438.1 - 1.7e-07 31.0 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain O-FucT PF10250.4 KII86439.1 - 3.7e-07 29.5 0.0 0.0035 16.4 0.0 3.0 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase MPC PF03650.8 KII86441.1 - 1.9e-37 127.8 0.1 2.2e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DNA_ligase_A_M PF01068.16 KII86442.1 - 1e-61 207.8 0.3 1.6e-61 207.2 0.2 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KII86442.1 - 2.5e-50 170.7 0.2 4.7e-50 169.8 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KII86442.1 - 1.6e-26 92.5 0.2 5.9e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KII86442.1 - 0.011 15.3 0.2 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Aa_trans PF01490.13 KII86443.1 - 9e-27 93.5 29.4 1.2e-26 93.2 20.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 KII86443.1 - 0.11 12.4 6.8 0.16 11.9 0.2 3.0 2 1 0 2 2 2 0 IBV 3C protein CAAD PF14159.1 KII86443.1 - 0.82 9.3 4.9 0.33 10.6 0.5 2.6 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase OppC_N PF12911.2 KII86444.1 - 0.13 11.6 5.0 0.48 9.8 3.5 2.0 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TrbL PF04610.9 KII86444.1 - 0.83 9.3 6.0 1.9 8.1 4.1 1.6 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Erf4 PF10256.4 KII86445.1 - 1.2e-24 86.4 0.0 1.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.23 KII86446.1 - 6e-49 161.7 24.8 2.2e-07 30.1 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KII86446.1 - 4.9e-46 150.9 19.1 2.3e-05 23.9 0.3 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 KII86446.1 - 3.6e-44 148.2 19.8 8.3e-10 38.1 0.1 7.1 1 1 8 10 10 10 10 TPR repeat TPR_8 PF13181.1 KII86446.1 - 8.2e-34 112.8 17.2 0.0013 18.3 1.7 10.4 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 KII86446.1 - 5.4e-30 103.1 18.0 5.3e-07 29.4 0.0 6.8 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KII86446.1 - 3.9e-29 100.6 15.6 2.5e-05 24.8 0.1 7.9 4 3 3 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 KII86446.1 - 1.4e-26 90.5 10.3 0.0017 18.8 0.0 9.6 4 2 6 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 KII86446.1 - 3.1e-25 85.9 9.0 0.027 14.2 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 KII86446.1 - 4.7e-22 76.8 10.0 0.034 14.5 0.0 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 KII86446.1 - 1.3e-21 74.9 26.2 0.00012 22.0 0.2 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KII86446.1 - 6.6e-21 74.4 16.4 3.8e-05 23.9 0.5 7.1 5 2 2 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KII86446.1 - 1.6e-11 44.1 13.4 3.8e-05 23.7 0.7 4.7 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KII86446.1 - 2.4e-10 40.0 15.6 0.022 14.6 0.2 6.3 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_15 PF13429.1 KII86446.1 - 1.8e-07 30.4 7.5 0.0016 17.5 0.5 4.5 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 KII86446.1 - 0.0011 19.0 2.6 0.0047 17.0 0.1 3.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 KII86446.1 - 0.0025 17.5 14.1 3.1 7.6 0.6 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 KII86446.1 - 0.0029 17.1 0.6 0.36 10.2 0.0 3.3 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 KII86446.1 - 0.004 15.9 0.5 2.2 6.9 0.0 2.4 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 KII86446.1 - 0.0051 15.9 9.6 0.19 10.8 0.2 4.2 2 2 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_21 PF09976.4 KII86446.1 - 0.033 14.1 13.6 0.1 12.5 1.4 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat 4F5 PF04419.9 KII86450.1 - 0.00017 22.2 32.3 0.035 14.8 22.4 2.4 1 1 0 1 1 1 1 4F5 protein family YscO PF07321.7 KII86450.1 - 0.17 11.6 11.9 0.19 11.5 8.2 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Brr6_like_C_C PF10104.4 KII86452.1 - 3.8e-42 143.0 1.5 4.7e-42 142.6 1.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Vpu PF00558.14 KII86452.1 - 0.18 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Vpu protein CLP_protease PF00574.18 KII86453.1 - 1e-68 230.5 0.0 1.3e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease AmoA PF05145.7 KII86454.1 - 0.053 12.5 0.2 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative ammonia monooxygenase PAP1 PF08601.5 KII86455.1 - 0.35 10.5 9.0 0.22 11.1 5.1 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 ImmE5 PF11480.3 KII86456.1 - 0.12 12.2 0.5 23 4.9 0.1 3.0 1 1 1 2 2 2 0 Colicin-E5 Imm protein DUF320 PF03777.8 KII86456.1 - 0.24 11.1 1.1 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 Small secreted domain (DUF320) Orthopox_F14 PF06076.7 KII86456.1 - 6.6 6.8 9.5 9.3 6.3 6.6 1.2 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Ribosomal_S17 PF00366.15 KII86457.1 - 7.1e-30 102.8 1.3 7.1e-30 102.8 0.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 Metallophos PF00149.23 KII86458.1 - 1.9e-41 141.6 0.1 2.5e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EmrE PF13536.1 KII86460.1 - 8.8e-08 32.3 13.7 8.8e-08 32.3 9.5 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DHFR_1 PF00186.14 KII86462.1 - 0.002 17.7 0.0 0.0061 16.1 0.0 1.8 1 1 1 2 2 2 1 Dihydrofolate reductase Ribosomal_L36 PF00444.13 KII86463.1 - 1.3e-18 66.6 10.4 1.5e-18 66.4 7.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Arc_trans_TRASH PF08394.5 KII86463.1 - 0.056 13.6 2.0 0.084 13.0 1.4 1.2 1 0 0 1 1 1 0 Archaeal TRASH domain RTA1 PF04479.8 KII86464.1 - 4.8e-44 150.5 6.0 7.6e-44 149.8 4.2 1.2 1 0 0 1 1 1 1 RTA1 like protein FMN_dh PF01070.13 KII86466.1 - 2.7e-82 276.4 0.1 1.4e-47 162.2 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 KII86466.1 - 0.00049 19.0 0.0 0.00091 18.2 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KII86466.1 - 0.00092 18.2 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Galactosyl_T PF01762.16 KII86467.1 - 5.1e-08 32.7 0.0 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase GST_C_2 PF13410.1 KII86468.1 - 1.6e-06 27.9 0.5 5.6e-06 26.1 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII86468.1 - 4e-06 26.9 0.0 8.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII86468.1 - 5.4e-05 23.1 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII86468.1 - 0.00062 19.7 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII86468.1 - 0.0092 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YopE_N PF09020.5 KII86468.1 - 0.026 14.5 1.3 0.084 12.9 0.4 2.0 2 0 0 2 2 2 0 YopE, N terminal GST_N_3 PF13417.1 KII86472.1 - 0.00058 20.0 0.0 0.00063 19.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII86472.1 - 0.05 13.6 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chitin_synth_2 PF03142.10 KII86474.1 - 0.099 11.0 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase BRF1 PF07741.8 KII86476.1 - 0.66 10.2 5.5 0.2 11.9 1.8 1.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GST_C_2 PF13410.1 KII86477.1 - 9.4e-07 28.6 1.1 3.3e-06 26.8 0.7 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII86477.1 - 6.7e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII86477.1 - 6.3e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII86477.1 - 0.00029 20.7 0.1 0.0012 18.7 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YopE_N PF09020.5 KII86477.1 - 0.0087 16.0 0.5 0.085 12.9 0.4 2.1 2 0 0 2 2 2 1 YopE, N terminal GST_N PF02798.15 KII86477.1 - 0.016 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SGS PF05002.10 KII86478.1 - 2.1e-30 104.2 3.8 3e-30 103.8 2.6 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KII86478.1 - 1.8e-08 34.8 0.0 2.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 CS domain PT-VENN PF04829.8 KII86478.1 - 0.6 9.7 0.0 0.6 9.7 0.0 2.0 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif UPF0052 PF01933.13 KII86481.1 - 3.6e-47 161.1 0.0 5.1e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Chorismate_synt PF01264.16 KII86482.1 - 9.8e-133 441.9 0.0 1.6e-132 441.2 0.0 1.3 1 1 0 1 1 1 1 Chorismate synthase SAP30_Sin3_bdg PF13867.1 KII86483.1 - 0.0005 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Reprolysin_5 PF13688.1 KII86485.1 - 5.4e-43 147.2 3.6 5.4e-43 147.2 2.5 2.6 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KII86485.1 - 1.7e-41 142.0 3.2 1.7e-40 138.7 0.2 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KII86485.1 - 1.1e-38 133.0 1.1 1.1e-38 133.0 0.7 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KII86485.1 - 3.9e-20 72.6 0.0 1.8e-19 70.4 0.0 2.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KII86485.1 - 3.4e-15 56.0 25.0 3.4e-15 56.0 17.3 4.6 2 1 2 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 KII86485.1 - 2.7e-07 30.4 0.1 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 KII86485.1 - 1.5e-06 27.9 5.9 1.8e-05 24.4 4.1 2.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M43 PF05572.8 KII86485.1 - 0.072 12.6 1.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A IncA PF04156.9 KII86485.1 - 0.6 9.6 0.8 1.3 8.5 0.6 1.4 1 0 0 1 1 1 0 IncA protein DEC-1_N PF04625.8 KII86486.1 - 1.6 7.2 11.9 2.2 6.8 8.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.11 KII86487.1 - 2.9e-26 92.0 44.7 3.3e-26 91.8 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1673 PF07895.6 KII86487.1 - 2.8 7.4 5.0 0.52 9.8 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) CDC48_2 PF02933.12 KII86488.1 - 0.44 10.2 4.8 33 4.2 3.4 3.1 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 FAM177 PF14774.1 KII86495.1 - 0.046 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 FAM177 family ABC_tran PF00005.22 KII86496.1 - 5.4e-47 159.5 0.0 4.8e-23 81.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 KII86496.1 - 4.9e-21 74.3 5.6 4.9e-21 74.3 3.9 2.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KII86496.1 - 1.8e-19 70.8 5.1 0.00015 21.8 0.0 5.0 4 1 0 5 5 5 4 AAA domain SMC_N PF02463.14 KII86496.1 - 5.7e-09 35.5 0.2 0.0079 15.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KII86496.1 - 3.4e-08 34.3 0.6 0.024 15.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KII86496.1 - 4.9e-08 32.3 0.1 0.0047 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KII86496.1 - 4.1e-07 30.4 0.0 0.034 14.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KII86496.1 - 5.3e-07 28.9 0.0 0.0076 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KII86496.1 - 9.4e-07 28.7 0.0 0.035 14.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 KII86496.1 - 2.1e-06 27.7 0.1 0.059 13.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KII86496.1 - 7.4e-06 25.7 0.1 0.15 11.7 0.0 2.6 3 0 0 3 3 2 2 NACHT domain AAA_22 PF13401.1 KII86496.1 - 1.8e-05 24.8 0.8 0.074 13.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KII86496.1 - 4.2e-05 23.8 5.3 0.4 10.9 0.0 4.7 5 0 0 5 5 5 2 AAA domain MobB PF03205.9 KII86496.1 - 0.0001 21.9 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KII86496.1 - 0.00053 18.8 0.1 0.64 8.7 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 KII86496.1 - 0.00091 18.6 0.0 0.81 9.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KII86496.1 - 0.0016 17.9 3.2 2.3 7.5 0.1 3.9 4 1 0 4 4 4 2 AAA-like domain RNA_helicase PF00910.17 KII86496.1 - 0.0031 17.6 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KII86496.1 - 0.0034 17.2 0.0 3.4 7.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KII86496.1 - 0.0049 17.0 0.1 6.4 6.9 0.0 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KII86496.1 - 0.0054 16.6 0.3 1.4 8.7 0.0 3.0 4 0 0 4 4 2 1 AAA domain AAA_23 PF13476.1 KII86496.1 - 0.006 16.9 15.8 0.017 15.4 0.0 4.5 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 KII86496.1 - 0.0063 16.5 8.9 0.29 11.0 1.4 3.5 3 2 0 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.1 KII86496.1 - 0.0067 16.3 2.8 0.39 10.6 0.1 3.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 KII86496.1 - 0.011 14.7 0.1 0.83 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KII86496.1 - 0.011 15.1 0.4 0.44 9.9 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_15 PF13175.1 KII86496.1 - 0.018 14.1 12.9 0.027 13.5 0.2 4.1 4 2 0 4 4 4 0 AAA ATPase domain DUF87 PF01935.12 KII86496.1 - 0.018 14.8 6.8 0.036 13.8 0.0 3.5 4 0 0 4 4 3 0 Domain of unknown function DUF87 cobW PF02492.14 KII86496.1 - 0.018 14.4 0.1 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KII86496.1 - 0.034 13.8 0.1 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KII86496.1 - 0.037 13.5 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KII86496.1 - 0.039 13.7 6.2 0.25 11.1 0.1 3.2 4 1 0 4 4 2 0 Dynamin family NB-ARC PF00931.17 KII86496.1 - 0.049 12.4 0.0 4.3 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 KII86496.1 - 0.051 13.2 1.1 2.1 8.0 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase ATP-synt_ab PF00006.20 KII86496.1 - 0.075 12.5 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 KII86496.1 - 0.076 12.7 0.2 4 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MutS_V PF00488.16 KII86496.1 - 0.11 11.8 0.0 9.4 5.5 0.0 2.2 2 0 0 2 2 2 0 MutS domain V DNA_topoisoIV PF00521.15 KII86497.1 - 7.5e-126 420.4 0.2 1.2e-125 419.6 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KII86497.1 - 6.4e-36 123.1 3.4 1.6e-35 121.8 2.4 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KII86497.1 - 3.5e-15 55.7 0.0 1.5e-14 53.8 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KII86497.1 - 3.9e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.24 KII86498.1 - 1.4e-44 151.5 0.0 1.1e-43 148.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII86498.1 - 7.9e-27 92.9 0.1 2.1e-25 88.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain MIP-T3 PF10243.4 KII86498.1 - 8.5e-05 21.2 23.8 0.00011 20.8 16.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CMS1 PF14617.1 KII86498.1 - 0.0053 15.8 0.0 0.0053 15.8 0.0 3.8 2 1 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Porph_ging PF09697.5 KII86498.1 - 0.13 12.4 0.5 1.2 9.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (Porph_ging) LytR_C PF13399.1 KII86498.1 - 1.4 9.3 10.1 12 6.3 0.0 5.1 5 2 1 6 6 6 0 LytR cell envelope-related transcriptional attenuator Oxysterol_BP PF01237.13 KII86499.1 - 7.7e-86 287.7 0.0 1e-85 287.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PCDO_beta_N PF12391.3 KII86499.1 - 0.045 13.1 0.9 1 8.8 0.0 2.5 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal PAM2 PF07145.10 KII86500.1 - 0.0042 16.4 13.7 0.27 10.8 0.1 4.2 4 0 0 4 4 4 3 Ataxin-2 C-terminal region DOT1 PF08123.8 KII86502.1 - 1.6e-64 216.9 0.0 2.2e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KII86502.1 - 0.00027 21.4 0.0 0.00054 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII86502.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KII86502.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 KII86503.1 - 1.2e-11 45.0 0.2 1.5e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DIOX_N PF14226.1 KII86504.1 - 1e-25 90.5 0.0 2e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII86504.1 - 1.2e-18 67.1 0.0 1.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nic96 PF04097.9 KII86506.1 - 3.8e-133 444.8 0.0 5e-133 444.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ST7 PF04184.7 KII86506.1 - 0.0019 16.5 0.7 0.0031 15.8 0.5 1.2 1 0 0 1 1 1 1 ST7 protein Spectrin PF00435.16 KII86506.1 - 0.039 14.2 0.1 0.79 10.0 0.0 3.2 3 1 1 4 4 4 0 Spectrin repeat ABC_tran PF00005.22 KII86507.1 - 8.3e-28 97.3 0.0 7.1e-27 94.3 0.0 2.6 3 1 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KII86507.1 - 1.5e-10 41.4 0.0 9.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KII86507.1 - 8.7e-07 28.3 0.0 0.02 13.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KII86507.1 - 3.6e-06 26.3 0.0 0.056 12.6 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KII86507.1 - 0.00055 20.3 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KII86507.1 - 0.0024 17.3 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KII86507.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 KII86507.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KII86507.1 - 0.025 14.5 0.2 0.11 12.4 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain DUF258 PF03193.11 KII86507.1 - 0.029 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KII86507.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KII86507.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KII86507.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KII86507.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_13 PF13166.1 KII86507.1 - 0.17 10.3 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.1 KII86508.1 - 4.8e-12 46.0 0.0 8.6e-09 35.3 0.0 3.1 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KII86508.1 - 1.2e-08 34.6 0.4 6.6e-07 28.9 0.2 2.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KII86508.1 - 0.00021 21.4 0.2 0.0067 16.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.1 KII86508.1 - 0.00038 20.5 0.1 0.012 15.7 0.0 2.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 KII86508.1 - 0.001 18.5 0.0 0.0028 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KII86508.1 - 0.0019 17.5 0.1 0.023 14.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain TPR_11 PF13414.1 KII86508.1 - 0.024 14.2 3.4 2.3 7.9 0.0 3.6 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KII86508.1 - 0.62 10.1 11.6 0.15 12.0 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Helicase_C PF00271.26 KII86510.1 - 8.9e-16 57.5 0.0 1.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII86510.1 - 1.1e-12 47.7 0.0 2.9e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KII86510.1 - 0.0024 17.7 0.0 0.025 14.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KII86510.1 - 0.042 12.4 0.0 0.061 11.8 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer HRDC PF00570.18 KII86510.1 - 0.094 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 HRDC domain Ras PF00071.17 KII86511.1 - 2.6e-64 215.4 0.0 3.1e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII86511.1 - 1.4e-19 70.7 0.0 2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII86511.1 - 2.1e-14 53.1 0.1 2.6e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII86511.1 - 7.2e-06 25.3 0.0 8.4e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KII86511.1 - 2.3e-05 23.9 0.1 5.8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII86511.1 - 0.00031 20.6 0.0 0.00056 19.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII86511.1 - 0.01 15.1 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 KII86511.1 - 0.029 14.3 0.1 0.053 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KII86511.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 KII86511.1 - 0.039 13.1 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KII86511.1 - 0.043 14.0 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII86511.1 - 0.048 13.8 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KII86511.1 - 0.065 12.4 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 KII86511.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 KII86511.1 - 0.1 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Septin Actin PF00022.14 KII86512.1 - 4e-49 167.0 0.0 1.2e-26 93.1 0.0 2.1 2 0 0 2 2 2 2 Actin RNA_pol_Rpc4 PF05132.9 KII86512.1 - 2.9 7.8 8.6 5.2 7.0 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 ADH_zinc_N PF00107.21 KII86514.1 - 3.3e-23 81.6 2.4 5.2e-23 81.0 1.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII86514.1 - 5.2e-17 62.9 1.3 1.1e-16 61.9 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII86514.1 - 1.1e-11 44.4 0.0 3.3e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KII86514.1 - 0.0037 16.8 0.9 0.0071 15.9 0.3 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KII86514.1 - 0.0067 15.9 0.1 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Histone PF00125.19 KII86515.1 - 3.6e-21 75.0 0.1 5.9e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII86515.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KII86515.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ABM PF03992.11 KII86515.1 - 0.012 15.6 0.0 0.066 13.2 0.0 2.0 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF1018 PF06252.7 KII86515.1 - 0.11 13.0 0.4 0.21 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 KII86516.1 - 2.8e-26 91.4 0.0 3.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII86516.1 - 2.1e-06 27.6 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABM PF03992.11 KII86517.1 - 5.6e-08 32.7 0.1 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase PBP PF01161.15 KII86518.1 - 6.9e-21 74.6 0.1 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein COG7 PF10191.4 KII86518.1 - 0.0029 15.6 0.1 0.0041 15.0 0.1 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Thiolase_N PF00108.18 KII86519.1 - 8.4e-08 31.5 0.0 8.4e-07 28.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KII86519.1 - 6.6e-06 25.5 0.1 9.7e-05 21.7 0.0 2.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KII86519.1 - 0.0019 17.8 0.2 0.19 11.3 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KII86519.1 - 0.087 12.2 4.0 0.48 9.8 0.4 2.6 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain PHD PF00628.24 KII86520.1 - 8.5e-12 44.5 7.2 1.4e-11 43.9 5.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KII86520.1 - 9.7e-06 24.8 1.7 1.7e-05 24.0 1.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 KII86520.1 - 0.0051 16.4 1.2 0.0099 15.5 0.8 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger zf-PHD-like PF15446.1 KII86520.1 - 0.027 13.7 1.6 0.052 12.8 1.1 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KII86520.1 - 0.12 12.1 7.0 0.031 13.9 2.7 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.16 KII86522.1 - 2.6e-18 65.6 7.6 2.6e-18 65.6 5.3 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 KII86522.1 - 6.2 6.9 9.6 6.3 6.9 3.1 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Sel1 PF08238.7 KII86524.1 - 3.5e-21 75.1 7.9 7.4e-07 29.6 0.0 3.2 3 0 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.1 KII86524.1 - 0.019 15.6 1.7 0.043 14.5 0.4 2.0 1 1 0 2 2 2 0 Tetratricopeptide repeat Tet_JBP PF12851.2 KII86527.1 - 2.8e-05 23.4 0.0 3.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Cauli_VI PF01693.11 KII86529.1 - 1.2e-05 25.1 2.3 1.2e-05 25.1 0.1 2.1 3 0 0 3 3 3 1 Caulimovirus viroplasmin VirC2 PF07181.6 KII86529.1 - 0.0087 15.4 0.4 0.012 15.0 0.3 1.1 1 0 0 1 1 1 1 VirC2 protein WSK PF03832.8 KII86538.1 - 0.29 10.5 0.9 0.5 9.7 0.6 1.2 1 0 0 1 1 1 0 WSK motif Pkinase PF00069.20 KII86545.1 - 3.6e-08 32.8 0.3 1.8e-06 27.2 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Exo_endo_phos_2 PF14529.1 KII86547.1 - 1.8e-09 37.2 0.0 3.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KII86547.1 - 3.2e-08 33.8 0.0 4.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 KII86549.1 - 1.3e-05 24.6 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cas_DxTHG PF09455.5 KII86549.1 - 0.11 11.6 0.1 0.12 11.4 0.1 1.3 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family F-box-like PF12937.2 KII86550.1 - 0.037 13.7 0.7 0.037 13.7 0.5 2.3 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.2 KII86551.1 - 0.16 11.7 3.3 0.17 11.6 0.1 2.5 2 1 0 2 2 2 0 F-box-like F-box-like PF12937.2 KII86553.1 - 0.025 14.3 0.4 0.025 14.3 0.3 2.5 3 0 0 3 3 3 0 F-box-like F-box PF00646.28 KII86553.1 - 0.086 12.5 0.8 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 F-box domain DUF4535 PF15054.1 KII86556.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Neur_chan_memb PF02932.11 KII86557.1 - 0.072 12.9 0.4 0.093 12.6 0.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med3 PF11593.3 KII86557.1 - 1.3 8.2 12.8 1.5 7.9 8.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1697 PF08002.6 KII86558.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) PQ-loop PF04193.9 KII86560.1 - 3.4e-20 71.3 3.4 1.4e-10 40.5 0.2 2.9 4 0 0 4 4 4 2 PQ loop repeat DUF2269 PF10027.4 KII86560.1 - 0.19 11.5 3.3 0.15 11.8 0.7 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) NMN_transporter PF04973.7 KII86560.1 - 0.74 9.2 6.4 0.22 10.9 1.2 2.1 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter eIF3_N PF09440.5 KII86561.1 - 1.3e-43 148.3 6.3 3.4e-43 146.9 1.3 2.8 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KII86561.1 - 2.2e-08 34.3 0.1 8e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KII86561.1 - 0.018 14.8 0.1 0.064 13.0 0.0 2.0 2 1 0 2 2 2 0 COP9 signalosome, subunit CSN8 Aminotran_1_2 PF00155.16 KII86562.1 - 1.5e-38 132.6 0.0 1.8e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KII86562.1 - 3.8e-05 22.1 0.0 5.5e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KII86562.1 - 6.6e-05 22.1 1.7 0.0001 21.4 1.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KII86562.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KII86562.1 - 0.0043 15.8 0.0 0.0071 15.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ELFV_dehydrog_N PF02812.13 KII86562.1 - 0.057 12.9 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF605 PF04652.11 KII86563.1 - 0.74 9.1 21.9 0.9 8.8 15.2 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KII86563.1 - 2.2 6.3 24.8 2.8 6.0 17.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF566 PF04484.7 KII86563.1 - 7.3 6.0 6.0 9.1 5.6 4.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIA PF03153.8 KII86563.1 - 9.5 6.0 13.0 12 5.6 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_32 PF13679.1 KII86565.1 - 1.9e-25 89.1 0.0 3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86565.1 - 6.7e-05 23.4 0.1 0.00013 22.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII86565.1 - 0.0038 17.2 1.0 0.009 16.0 0.7 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII86565.1 - 0.0046 16.3 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KII86565.1 - 0.0087 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII86565.1 - 0.01 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KII86565.1 - 0.037 14.5 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KII86565.1 - 0.05 12.9 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TRM13 PF05206.9 KII86565.1 - 0.064 12.4 0.0 0.16 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase TRM13 Methyltransf_23 PF13489.1 KII86565.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KII86568.1 - 9.6e-60 202.4 0.0 2.2e-59 201.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Homeobox_KN PF05920.6 KII86569.1 - 2.5e-16 59.0 0.1 2.5e-16 59.0 0.0 2.3 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 KII86569.1 - 0.00015 21.3 0.1 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain DUF4175 PF13779.1 KII86569.1 - 1.1 6.9 3.8 1.5 6.4 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LRR_4 PF12799.2 KII86570.1 - 4.1e-33 112.4 26.3 9.1e-07 28.3 0.1 9.3 6 1 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII86570.1 - 2.2e-23 81.7 35.1 1.1e-06 28.2 0.5 6.5 3 1 6 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 KII86570.1 - 1.4e-09 36.6 30.2 1.8 8.9 0.1 11.5 9 2 1 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 KII86570.1 - 2.9e-08 32.5 35.0 6 7.5 0.0 12.5 13 0 0 13 13 13 4 Leucine rich repeat LRR_9 PF14580.1 KII86570.1 - 0.0028 17.2 10.8 2.6 7.5 0.1 4.7 3 1 2 5 5 5 2 Leucine-rich repeat LRR_6 PF13516.1 KII86570.1 - 0.025 14.6 25.8 5.2 7.4 0.0 9.3 11 0 0 11 11 11 0 Leucine Rich repeat PaaSYMP PF14738.1 KII86572.1 - 0.055 13.1 0.1 0.086 12.5 0.0 1.4 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 SAMP PF05924.6 KII86575.1 - 0.49 9.6 0.0 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 SAMP Motif Pkinase PF00069.20 KII86576.1 - 0.00053 19.2 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII86576.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Oxidored_FMN PF00724.15 KII86578.1 - 9.4e-50 169.5 0.0 1.2e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_3 PF07859.8 KII86579.1 - 6e-16 58.6 0.4 4.8e-15 55.7 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KII86579.1 - 1.2e-10 40.7 0.0 5e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KII86579.1 - 1.1e-07 31.7 0.1 1.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII86579.1 - 0.00019 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Pkinase PF00069.20 KII86580.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain F-box-like PF12937.2 KII86581.1 - 6.3e-05 22.6 0.1 0.00015 21.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86581.1 - 0.00047 19.7 0.2 0.00092 18.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII86582.1 - 0.011 15.4 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 F-box-like DUF1762 PF08574.5 KII86583.1 - 2.2e-08 34.3 9.2 2.2e-08 34.3 6.4 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1762) Nop14 PF04147.7 KII86583.1 - 7 4.4 16.4 13 3.5 11.4 1.4 1 1 0 1 1 1 0 Nop14-like family Caleosin PF05042.8 KII86584.1 - 1.7e-39 135.1 0.0 1.9e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein COX1 PF00115.15 KII86584.1 - 0.075 11.6 0.1 0.13 10.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF3035 PF11233.3 KII86585.1 - 0.44 10.5 5.4 0.47 10.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Glyco_hydro_16 PF00722.16 KII86586.1 - 2.2e-07 30.3 0.0 9e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 7tm_7 PF08395.7 KII86587.1 - 0.0098 14.9 1.8 0.0098 14.9 1.3 1.9 1 1 0 1 1 1 1 7tm Chemosensory receptor F-box-like PF12937.2 KII86589.1 - 0.00061 19.4 0.1 0.0019 17.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like Mif2_N PF15624.1 KII86590.1 - 0.28 11.7 1.8 0.39 11.2 1.1 1.4 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Totivirus_coat PF05518.6 KII86590.1 - 3.2 5.4 6.4 3.2 5.4 4.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein mit_SMPDase PF14724.1 KII86590.1 - 5.7 4.6 5.0 7.3 4.2 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase ICMT PF04140.9 KII86592.1 - 6.2e-13 48.7 0.1 8.3e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII86592.1 - 1.2e-10 41.4 2.7 3e-09 36.9 0.1 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KII86592.1 - 6.9e-05 21.5 0.0 0.00013 20.6 0.0 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UPF0126 PF03458.8 KII86592.1 - 0.049 13.2 0.4 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 UPF0126 domain ICMT PF04140.9 KII86593.1 - 1.5e-13 50.7 0.3 4.5e-12 46.0 0.0 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII86593.1 - 8.2e-11 41.9 0.9 5e-09 36.2 0.2 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KII86593.1 - 2.5e-06 26.3 0.0 3.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MerE PF05052.7 KII86593.1 - 0.074 13.0 0.4 0.25 11.3 0.2 2.0 1 0 0 1 1 1 0 MerE protein Pkinase PF00069.20 KII86594.1 - 1e-17 64.1 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86594.1 - 3e-08 33.0 0.0 4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII86594.1 - 5.9e-06 26.1 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII86594.1 - 4.8e-05 22.5 0.0 6.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII86594.1 - 0.00028 20.3 0.1 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KII86594.1 - 0.0029 16.6 0.0 0.0035 16.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KII86594.1 - 0.13 11.0 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sulfatase PF00884.18 KII86595.1 - 6.6e-50 170.0 0.0 8.9e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KII86595.1 - 0.0023 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KII86595.1 - 0.11 10.9 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) F-box-like PF12937.2 KII86597.1 - 1.4e-05 24.7 0.1 5.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII86597.1 - 0.029 14.0 0.5 0.23 11.1 0.0 2.8 3 0 0 3 3 3 0 F-box domain HVSL PF09749.4 KII86598.1 - 1.6e-43 148.4 0.0 3.6e-43 147.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein CMV_US PF08001.6 KII86598.1 - 0.0045 16.0 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 CMV US MFS_1 PF07690.11 KII86599.1 - 2.2e-43 148.3 17.4 4.5e-43 147.3 12.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII86599.1 - 2.5e-09 36.2 21.4 5.7e-09 35.0 3.2 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KII86599.1 - 5.3e-07 28.3 10.7 7.5e-07 27.8 1.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 KII86599.1 - 3.3e-06 25.5 9.8 2.4e-05 22.6 2.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 KII86599.1 - 0.0037 15.3 0.1 0.0071 14.4 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.1 KII86599.1 - 0.5 9.7 11.4 0.44 9.9 0.1 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4131) TPPK_C PF12555.3 KII86599.1 - 0.9 9.3 8.1 6.3 6.6 0.0 3.9 4 0 0 4 4 4 0 Thiamine pyrophosphokinase C terminal cobW PF02492.14 KII86600.1 - 1.5e-33 115.6 0.0 1.9e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KII86600.1 - 4.6e-05 22.3 0.1 0.011 14.4 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 KII86600.1 - 0.0022 18.7 0.1 0.0052 17.5 0.1 1.7 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KII86600.1 - 0.0026 17.6 0.0 0.0053 16.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KII86600.1 - 0.0048 17.1 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KII86600.1 - 0.026 13.9 0.1 1.1 8.6 0.1 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TIP49 PF06068.8 KII86600.1 - 0.031 13.0 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 KII86600.1 - 0.056 13.1 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KII86600.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KII86600.1 - 0.08 12.3 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KII86600.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 KII86600.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.7 KII86600.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Acetyltransf_7 PF13508.1 KII86601.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII86601.1 - 0.038 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KII86602.1 - 8.6e-36 123.3 40.6 8.6e-36 123.3 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KII86602.1 - 8.9e-06 24.1 1.7 1.7e-05 23.2 1.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KII86602.1 - 0.00071 18.2 36.8 0.0093 14.5 25.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter F-box-like PF12937.2 KII86603.1 - 0.00059 19.5 0.1 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86603.1 - 0.011 15.4 0.8 0.17 11.5 0.0 2.9 3 0 0 3 3 3 0 F-box domain PRRSV_Env PF02340.10 KII86603.1 - 0.019 14.1 0.2 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 PRRSV putative envelope protein LRR_1 PF00560.28 KII86603.1 - 0.089 12.8 6.9 2 8.7 0.2 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat Opi1 PF08618.5 KII86604.1 - 0.066 12.1 1.2 0.074 11.9 0.8 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 adh_short PF00106.20 KII86605.1 - 2.3e-30 105.7 0.3 2.3e-30 105.7 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII86605.1 - 4.1e-10 39.5 0.5 9.3e-10 38.4 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KII86605.1 - 7.7e-08 32.3 0.0 9.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KII86605.1 - 3.7e-06 26.2 0.0 5.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KII86605.1 - 1.6e-05 24.4 0.1 3.6e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KII86605.1 - 4.6e-05 23.1 0.9 9.2e-05 22.1 0.7 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KII86605.1 - 0.0035 17.3 0.4 0.0053 16.7 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII86605.1 - 0.029 13.6 0.1 0.051 12.8 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family DUF4637 PF15470.1 KII86608.1 - 0.046 13.3 0.3 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1880 PF08976.6 KII86610.1 - 2.3 8.3 6.3 0.74 9.9 0.7 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1880) RAP1 PF07218.6 KII86610.1 - 5.1 5.0 4.5 7 4.6 3.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ATP-synt_8 PF00895.15 KII86611.1 - 0.13 12.5 1.2 0.23 11.6 0.8 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 GST_N_3 PF13417.1 KII86613.1 - 1.6e-12 47.4 0.1 2.8e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII86613.1 - 6.5e-10 38.8 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII86613.1 - 1.3e-08 34.5 0.4 2.8e-08 33.5 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII86613.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII86613.1 - 0.04 14.3 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KII86613.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin adh_short PF00106.20 KII86615.1 - 1.2e-16 61.1 1.5 2e-16 60.3 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII86615.1 - 9.7e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII86615.1 - 1.2e-06 28.3 0.3 1.5e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_6 PF08030.7 KII86617.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KII86617.1 - 6.5e-14 52.0 9.9 1.3e-13 51.0 6.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KII86617.1 - 1.5e-07 31.2 0.0 3.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ribosomal_L34 PF00468.12 KII86618.1 - 6.4e-19 67.3 11.0 9.9e-19 66.7 7.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Rrn6 PF10214.4 KII86618.1 - 0.013 13.6 1.7 0.014 13.4 1.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_C97 PF05903.9 KII86619.1 - 6.4e-39 133.1 0.0 9.3e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 KII86619.1 - 7.7e-25 87.1 0.0 1.2e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 KII86619.1 - 1.3e-11 44.0 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KII86619.1 - 0.00027 21.1 0.1 0.026 14.7 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain CLASP_N PF12348.3 KII86620.1 - 2.2e-23 82.8 0.0 3.2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 KII86620.1 - 0.2 11.8 1.1 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat SET PF00856.23 KII86621.1 - 8.6e-11 42.4 0.3 8.9e-09 35.8 0.0 2.7 2 1 0 2 2 2 1 SET domain SAF PF08666.7 KII86621.1 - 0.12 12.7 0.4 8.9 6.8 0.1 2.4 2 0 0 2 2 2 0 SAF domain SET PF00856.23 KII86622.1 - 1e-08 35.6 0.1 0.00017 21.9 0.0 2.3 1 1 0 2 2 2 2 SET domain SAF PF08666.7 KII86622.1 - 0.00085 19.6 0.2 0.23 11.8 0.0 2.5 2 0 0 2 2 2 2 SAF domain TPR_11 PF13414.1 KII86622.1 - 0.014 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 KII86622.1 - 0.072 13.4 0.1 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.2 KII86623.1 - 5.2e-05 22.8 0.3 5.2e-05 22.8 0.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KII86623.1 - 0.0013 18.2 0.1 0.0013 18.2 0.1 2.8 3 0 0 3 3 3 1 F-box domain CMAS PF02353.15 KII86625.1 - 1.1e-53 182.1 0.0 7.7e-41 139.9 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KII86625.1 - 1.1e-08 35.6 0.0 3.5e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KII86625.1 - 8.6e-07 28.4 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KII86625.1 - 2.1e-05 24.3 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII86625.1 - 9.7e-05 22.6 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII86625.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII86625.1 - 0.00018 21.9 0.0 0.0004 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII86625.1 - 0.00041 19.9 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KII86625.1 - 0.0051 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KII86625.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 KII86625.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GCD14 PF08704.5 KII86625.1 - 0.033 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Met_10 PF02475.11 KII86625.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.12 KII86625.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RRM_1 PF00076.17 KII86626.1 - 2e-09 36.9 0.0 3.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII86626.1 - 4.8e-06 26.4 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII86626.1 - 3.2e-05 23.7 0.2 9.1e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KII86626.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KII86626.1 - 0.0098 15.7 0.0 0.031 14.1 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 KII86627.1 - 3e-11 43.8 0.3 6.6e-09 36.2 0.2 2.6 2 1 0 2 2 2 1 SET domain SAF PF08666.7 KII86627.1 - 0.021 15.1 0.1 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain ChiC PF06483.6 KII86627.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Chitinase C SET PF00856.23 KII86628.1 - 1.8e-12 47.8 0.5 3.1e-07 30.8 0.0 3.3 2 1 1 3 3 3 2 SET domain SAF PF08666.7 KII86628.1 - 0.0029 17.9 0.1 0.45 10.9 0.0 2.4 2 0 0 2 2 2 2 SAF domain TPR_11 PF13414.1 KII86628.1 - 0.1 12.2 1.0 0.31 10.7 0.7 1.8 1 1 0 1 1 1 0 TPR repeat Methyltransf_31 PF13847.1 KII86629.1 - 2.3e-17 62.9 0.0 3.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII86629.1 - 3.7e-14 52.9 0.1 8.4e-14 51.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII86629.1 - 4.6e-14 52.4 0.0 6.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86629.1 - 9.6e-13 48.7 0.0 1.7e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII86629.1 - 2.1e-12 47.3 0.0 3.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII86629.1 - 3.7e-10 39.3 0.0 7.8e-10 38.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KII86629.1 - 1.5e-09 37.7 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KII86629.1 - 4.2e-09 36.0 0.0 7.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KII86629.1 - 2.5e-07 30.9 0.0 4.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KII86629.1 - 3.3e-05 22.7 0.0 4.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 KII86629.1 - 0.00013 21.2 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KII86629.1 - 0.0003 20.7 0.1 0.00094 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KII86629.1 - 0.0007 19.1 0.0 0.00091 18.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.15 KII86629.1 - 0.0043 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 KII86629.1 - 0.0045 16.5 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 KII86629.1 - 0.0074 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KII86629.1 - 0.0085 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 KII86629.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 KII86629.1 - 0.022 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DREV PF05219.7 KII86629.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DOT1 PF08123.8 KII86629.1 - 0.049 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF3087 PF11286.3 KII86630.1 - 1.4 8.1 4.3 0.57 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Abhydrolase_5 PF12695.2 KII86631.1 - 8.4e-21 74.2 0.1 1.5e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII86631.1 - 9e-17 61.7 2.7 2.1e-16 60.4 1.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII86631.1 - 8.4e-12 45.1 0.1 3.9e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KII86631.1 - 6.3e-09 35.7 0.3 1.1e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII86631.1 - 1.6e-05 24.1 0.0 0.00012 21.3 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 KII86631.1 - 0.0019 18.4 0.0 0.0056 16.9 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 KII86631.1 - 0.0031 16.9 0.1 0.051 12.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DUF218 PF02698.12 KII86631.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain Ser_hydrolase PF06821.8 KII86631.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DLH PF01738.13 KII86631.1 - 0.018 14.3 0.0 1.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 KII86631.1 - 0.038 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.7 KII86631.1 - 0.042 12.5 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.13 KII86631.1 - 0.044 13.2 0.0 0.7 9.2 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3089 PF11288.3 KII86631.1 - 0.051 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 KII86631.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 KII86631.1 - 0.052 13.4 0.1 0.3 10.9 0.0 2.3 2 1 1 3 3 3 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KII86631.1 - 0.1 12.0 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase HCO3_cotransp PF00955.16 KII86632.1 - 5.2e-60 203.5 6.3 2.6e-31 108.8 1.4 3.0 2 1 1 3 3 3 3 HCO3- transporter family His_Phos_2 PF00328.17 KII86633.1 - 2e-07 30.6 0.0 1.7e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KII86633.1 - 0.024 14.7 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF2613 PF11021.3 KII86633.1 - 0.57 9.9 4.9 0.46 10.2 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) F-box-like PF12937.2 KII86634.1 - 3.9e-10 39.2 0.5 3.9e-10 39.2 0.4 1.9 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KII86634.1 - 0.0056 16.4 0.0 1 9.1 0.0 2.9 2 1 1 3 3 3 1 Leucine rich repeat BSD PF03909.12 KII86634.1 - 0.11 12.2 0.1 10 5.9 0.0 2.6 2 0 0 2 2 2 0 BSD domain AMP-binding PF00501.23 KII86637.1 - 3.2e-89 299.1 0.0 4e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII86637.1 - 8.5e-16 58.6 0.2 3.1e-15 56.8 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SET PF00856.23 KII86638.1 - 7.9e-05 23.0 0.0 0.0014 19.0 0.0 2.1 1 1 0 1 1 1 1 SET domain Amidohydro_2 PF04909.9 KII86639.1 - 7.3e-29 101.1 0.0 1.2e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KII86639.1 - 1.1e-05 24.8 0.0 7.1e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 TatD related DNase CReP_N PF10472.4 KII86639.1 - 0.091 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor BTB PF00651.26 KII86641.1 - 0.0016 18.3 0.1 0.0089 16.0 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain Mito_carr PF00153.22 KII86642.1 - 5.7e-77 253.5 0.1 8.4e-27 92.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tyrosinase PF00264.15 KII86644.1 - 9.3e-30 104.4 5.2 1.3e-29 103.9 3.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 KII86645.1 - 1.6e-30 106.9 4.5 2.3e-30 106.4 3.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase GPI-anchored PF10342.4 KII86646.1 - 1.3e-09 38.3 0.2 2.1e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII86646.1 - 0.0064 16.0 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KII86647.1 - 8.2e-08 32.6 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EBP PF05241.7 KII86649.1 - 1e-62 210.6 6.0 1.3e-62 210.3 4.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3302 PF11742.3 KII86649.1 - 0.11 12.3 1.9 2.5 8.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) Glyco_hydro_16 PF00722.16 KII86650.1 - 8.1e-05 21.9 0.0 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 GPI-anchored PF10342.4 KII86651.1 - 6.5e-08 32.9 0.0 9.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII86651.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3304 PF11745.3 KII86651.1 - 0.078 13.1 0.1 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) GPI-anchored PF10342.4 KII86653.1 - 1.3e-08 35.2 0.1 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII86653.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4448 PF14610.1 KII86654.1 - 0.049 13.1 2.4 0.82 9.1 1.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3304 PF11745.3 KII86654.1 - 0.07 13.3 0.9 0.15 12.2 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3304) DUF4083 PF13314.1 KII86654.1 - 0.84 9.5 2.8 0.77 9.6 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Ashwin PF15323.1 KII86654.1 - 8.1 6.3 11.9 12 5.8 8.2 1.3 1 0 0 1 1 1 0 Developmental protein Amidohydro_2 PF04909.9 KII86655.1 - 1.7e-29 103.2 0.2 2.1e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase GPI-anchored PF10342.4 KII86656.1 - 2e-06 28.2 0.0 2e-06 28.2 0.0 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII86656.1 - 0.0068 15.9 0.0 0.031 13.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CHRD PF07452.7 KII86656.1 - 0.14 12.8 0.0 0.14 12.8 0.0 2.3 2 1 0 2 2 2 0 CHRD domain Pol_alpha_B_N PF08418.5 KII86656.1 - 8.8 5.7 12.0 11 5.4 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DPBB_1 PF03330.13 KII86657.1 - 2.2e-05 24.3 0.0 5.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ribosomal_L37e PF01907.14 KII86657.1 - 0.0069 16.1 1.4 0.0093 15.7 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L37e Barwin PF00967.12 KII86657.1 - 0.037 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Barwin family zf-RING_3 PF14369.1 KII86657.1 - 0.18 11.8 1.6 0.81 9.7 0.7 2.3 2 1 0 2 2 2 0 zinc-finger Ubiq_cyt_C_chap PF03981.7 KII86659.1 - 5.5e-24 84.6 0.1 1.9e-12 47.2 0.0 2.9 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone SH3_9 PF14604.1 KII86660.1 - 1.5e-22 78.8 0.6 5.2e-13 48.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KII86660.1 - 6.2e-20 70.4 0.1 1.3e-10 40.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KII86660.1 - 6.8e-19 66.9 0.6 5.2e-08 32.1 0.4 2.8 2 1 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KII86660.1 - 1.5e-12 46.9 4.7 2.6e-12 46.2 3.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.18 KII86660.1 - 2.5e-12 46.7 3.9 2.8e-11 43.4 0.0 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.6 KII86660.1 - 0.00035 20.7 0.4 0.00035 20.7 0.3 2.4 2 1 0 2 2 2 1 Bacterial SH3 domain Antitoxin-MazE PF04014.13 KII86660.1 - 0.083 12.6 0.6 4.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE CAF1 PF04857.15 KII86661.1 - 1.3e-66 224.6 0.0 2.1e-66 223.9 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease Fungal_trans PF04082.13 KII86662.1 - 5.8e-19 67.9 1.8 1.3e-18 66.8 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII86662.1 - 0.00012 21.9 10.8 0.00021 21.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NinF PF05810.7 KII86662.1 - 0.57 10.0 3.9 1.3 8.9 2.7 1.5 1 0 0 1 1 1 0 NinF protein Fungal_trans PF04082.13 KII86663.1 - 5.8e-14 51.5 0.4 5.8e-14 51.5 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII86663.1 - 0.0006 19.6 13.4 0.0011 18.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 KII86663.1 - 0.13 12.0 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Serglycin Carn_acyltransf PF00755.15 KII86664.1 - 2.1e-161 538.0 0.0 2.4e-161 537.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3653 PF12375.3 KII86664.1 - 0.29 11.3 6.9 0.34 11.1 0.3 3.0 2 1 0 2 2 2 0 Phage protein MFS_1 PF07690.11 KII86665.1 - 1.3e-40 139.2 45.4 8.1e-39 133.3 33.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII86665.1 - 5.3e-12 45.0 8.2 5.3e-12 45.0 5.7 3.6 2 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 KII86665.1 - 7.7e-12 44.2 15.8 1.2e-11 43.5 10.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3392 PF11872.3 KII86665.1 - 1.1 9.2 6.7 2 8.3 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) Tyrosinase PF00264.15 KII86666.1 - 1.7e-25 90.5 0.9 2.3e-25 90.0 0.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Aldo_ket_red PF00248.16 KII86667.1 - 1.6e-50 171.5 0.0 2.1e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.26 KII86668.1 - 0.0028 17.6 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain APH PF01636.18 KII86669.1 - 0.0074 16.0 0.2 0.37 10.4 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DASH_Dad1 PF08649.5 KII86670.1 - 1.1e-14 53.8 0.1 1.4e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Pkinase PF00069.20 KII86671.1 - 3.5e-65 219.7 0.0 6.2e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86671.1 - 1.2e-35 122.8 0.0 2e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KII86671.1 - 8e-20 70.3 27.9 5.9e-11 41.9 6.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 KII86671.1 - 8.2e-20 70.3 29.8 2e-15 56.2 2.8 2.7 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.19 KII86671.1 - 5.4e-10 39.6 0.8 1.4e-09 38.2 0.1 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 KII86671.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Uds1 PF15456.1 KII86671.1 - 0.88 9.5 16.1 4.5 7.2 1.3 2.8 2 0 0 2 2 2 0 Up-regulated During Septation DUF605 PF04652.11 KII86671.1 - 1.3 8.3 33.0 1.4 8.2 1.7 2.3 2 0 0 2 2 2 0 Vta1 like DUF3871 PF12987.2 KII86672.1 - 0.018 13.7 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) Endosulfine PF04667.12 KII86673.1 - 5.1e-20 71.2 0.0 8.3e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Aldo_ket_red PF00248.16 KII86674.1 - 2.5e-71 239.8 0.0 2.8e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII86675.1 - 4.3e-71 239.0 0.0 5.3e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_red_lgC PF02867.10 KII86676.1 - 1.1e-209 697.4 0.0 1.5e-209 697.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KII86676.1 - 3.8e-24 84.3 0.1 1.2e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KII86676.1 - 2.7e-16 59.7 0.0 7e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain GTP_EFTU PF00009.22 KII86678.1 - 8e-53 178.6 0.0 1.2e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KII86678.1 - 3.4e-15 55.6 0.0 8.8e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KII86678.1 - 6.4e-09 35.5 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KII86678.1 - 7.8e-07 29.1 0.0 2.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII86678.1 - 2.2e-05 24.4 0.0 4.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 KII86678.1 - 0.011 15.2 0.0 0.81 9.2 0.0 2.9 2 1 1 3 3 3 0 Elongation factor G, domain IV Miro PF08477.8 KII86678.1 - 0.026 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 KII86678.1 - 0.079 12.1 0.0 0.66 9.1 0.1 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit SGT1 PF07093.6 KII86678.1 - 1.1 7.5 4.2 0.15 10.4 0.1 1.5 2 0 0 2 2 2 0 SGT1 protein DUF427 PF04248.7 KII86679.1 - 1.5e-29 101.5 0.3 1.7e-29 101.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) 4HBT_3 PF13622.1 KII86680.1 - 5e-36 124.7 3.2 6e-36 124.4 2.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily XdhC_CoxI PF02625.11 KII86680.1 - 0.086 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 XdhC and CoxI family zf-DHHC PF01529.15 KII86681.1 - 2.3e-36 124.7 6.0 2.3e-36 124.7 4.1 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 KII86681.1 - 0.042 13.6 4.7 0.081 12.7 3.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon QueC PF06508.8 KII86681.1 - 0.56 9.4 2.5 0.91 8.7 1.7 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Methyltransf_33 PF10017.4 KII86682.1 - 3.3e-35 120.7 0.2 5.5e-35 120.0 0.1 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KII86682.1 - 8.9e-24 84.2 1.8 4.4e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KII86682.1 - 0.00014 22.1 0.2 0.00026 21.3 0.1 1.4 1 0 0 1 1 1 1 DinB superfamily Gelsolin PF00626.17 KII86683.1 - 1.1e-37 127.5 0.1 3.1e-17 62.0 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat CodY PF06018.9 KII86683.1 - 0.043 13.0 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 CodY GAF-like domain WD40 PF00400.27 KII86684.1 - 2.3e-13 49.4 11.1 0.00027 20.6 0.1 6.0 7 1 0 7 7 7 3 WD domain, G-beta repeat Aldo_ket_red PF00248.16 KII86685.1 - 4.4e-69 232.4 0.0 5e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII86686.1 - 1.7e-67 227.2 0.0 1.9e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2 PF00096.21 KII86687.1 - 1.7e-10 40.5 9.9 2.5e-05 24.3 1.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII86687.1 - 3e-10 39.8 16.1 1.8e-07 31.0 2.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII86687.1 - 1.3e-07 31.4 10.3 0.00056 20.0 1.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII86687.1 - 0.15 12.2 0.6 6.6 7.0 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Aldo_ket_red PF00248.16 KII86688.1 - 6.5e-70 235.1 0.0 8e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arrestin_N PF00339.24 KII86689.1 - 0.074 12.8 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Asp PF00026.18 KII86690.1 - 3.1e-50 171.2 18.9 6.5e-50 170.1 13.1 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII86690.1 - 3.3e-05 23.8 7.4 7.7e-05 22.7 3.2 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII86690.1 - 0.00029 21.2 6.1 0.034 14.6 1.3 3.0 2 0 0 2 2 2 2 Aspartyl protease Asp PF00026.18 KII86691.1 - 8e-41 140.3 0.7 1.2e-40 139.7 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII86691.1 - 0.00024 21.5 1.9 0.049 14.1 0.4 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 KII86691.1 - 0.011 15.5 0.9 0.46 10.3 0.1 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PAPA-1 PF04795.7 KII86692.1 - 2.1e-16 60.3 2.1 3.8e-16 59.5 1.4 1.5 1 0 0 1 1 1 1 PAPA-1-like conserved region FixH PF05751.6 KII86693.1 - 0.059 13.1 0.0 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 FixH RRM_6 PF14259.1 KII86694.1 - 2.6e-15 56.1 0.1 7.6e-11 41.8 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII86694.1 - 4e-11 42.3 0.6 0.00012 21.6 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII86694.1 - 5.6e-09 35.7 0.4 0.0088 15.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KII86695.1 - 1.1e-45 155.8 42.8 5.9e-33 114.0 10.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII86695.1 - 6.2e-10 38.2 10.9 6.2e-10 38.2 7.6 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 KII86695.1 - 0.00027 19.2 10.8 0.00027 19.2 7.5 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Oxidored_FMN PF00724.15 KII86696.1 - 1.9e-52 178.3 0.0 2.6e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMO-like PF00743.14 KII86697.1 - 2.1e-23 82.3 0.0 7.2e-12 44.2 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII86697.1 - 2.2e-14 53.9 0.0 5.3e-09 36.4 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII86697.1 - 5e-10 39.5 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII86697.1 - 5.9e-09 35.8 0.0 5.4e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KII86697.1 - 1.8e-07 30.4 0.0 7.3e-06 25.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KII86697.1 - 0.0003 19.9 0.0 0.0013 17.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KII86697.1 - 0.0006 18.8 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII86697.1 - 0.0016 17.6 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KII86697.1 - 0.0028 17.4 0.1 0.015 15.1 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KII86697.1 - 0.011 14.1 0.0 0.052 12.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 KII86697.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pectinesterase PF01095.14 KII86698.1 - 3e-37 127.7 4.0 3.7e-37 127.4 2.8 1.0 1 0 0 1 1 1 1 Pectinesterase XPG_N PF00752.12 KII86699.1 - 1.4e-33 115.1 0.0 2.8e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KII86699.1 - 4.7e-28 97.0 0.0 9.8e-28 96.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KII86699.1 - 1.8e-05 24.9 0.1 4.7e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.10 KII86699.1 - 0.0067 16.0 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain DUF2637 PF10935.3 KII86701.1 - 0.0092 15.9 0.8 0.014 15.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2637) DUF4305 PF14146.1 KII86701.1 - 0.17 11.6 3.9 0.11 12.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) Glyco_hydro_35 PF01301.14 KII86702.1 - 3.2e-68 230.4 0.2 5.3e-44 150.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KII86702.1 - 6.3e-44 148.7 11.5 1.7e-23 83.0 0.4 3.5 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KII86702.1 - 2.7e-37 127.9 7.0 4.1e-37 127.3 4.9 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KII86702.1 - 4.1e-19 67.7 0.5 1.4e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.9 KII86702.1 - 0.097 12.2 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase MFS_1 PF07690.11 KII86703.1 - 5.3e-14 51.6 53.3 2.5e-10 39.6 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nop16 PF09420.5 KII86704.1 - 6.1 6.9 12.8 0.93 9.5 4.8 2.1 1 1 1 2 2 2 0 Ribosome biogenesis protein Nop16 NAD_binding_8 PF13450.1 KII86705.1 - 1.2e-13 50.8 0.0 2.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KII86705.1 - 4.1e-13 49.2 0.0 3.8e-05 22.9 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KII86705.1 - 5.5e-06 26.5 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII86705.1 - 3.7e-05 22.8 0.1 0.0016 17.4 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII86705.1 - 3.7e-05 23.5 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 KII86705.1 - 0.042 12.3 0.0 1.2 7.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KII86705.1 - 0.073 13.4 0.0 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Na_H_Exchanger PF00999.16 KII86706.1 - 5.6e-58 196.2 23.0 6.6e-58 196.0 15.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KII86706.1 - 0.07 13.0 4.0 0.82 9.6 0.1 2.9 2 0 0 2 2 2 0 YrhC-like protein zf-RING_5 PF14634.1 KII86708.1 - 0.0001 21.9 3.4 0.00018 21.1 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII86708.1 - 0.086 12.8 5.8 0.17 11.9 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KII86708.1 - 2.4 8.1 7.1 19 5.3 4.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain F-box PF00646.28 KII86711.1 - 5.7e-08 32.2 0.6 1.3e-07 31.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII86711.1 - 2.6e-06 27.0 0.2 6.4e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like Pex24p PF06398.6 KII86713.1 - 2e-31 109.0 4.9 3.8e-31 108.1 3.4 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DSPc PF00782.15 KII86714.1 - 3.8e-25 88.0 0.0 4.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII86714.1 - 0.0014 18.0 0.1 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DDDD PF10161.4 KII86714.1 - 0.086 12.4 0.1 0.46 10.1 0.0 2.1 2 1 0 2 2 2 0 Putative mitochondrial precursor protein PTPlike_phytase PF14566.1 KII86714.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate F-box-like PF12937.2 KII86715.1 - 1.2e-08 34.5 0.7 2.3e-08 33.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86715.1 - 0.028 14.0 0.0 2 8.1 0.1 2.5 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 KII86715.1 - 0.13 12.0 0.1 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain ketoacyl-synt PF00109.21 KII86717.1 - 1.8e-81 273.3 0.0 3.9e-81 272.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KII86717.1 - 1.8e-53 181.9 0.0 2.8e-51 174.7 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KII86717.1 - 1.4e-36 124.9 0.1 3.4e-36 123.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KII86717.1 - 6.3e-25 87.9 0.2 1.2e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KII86717.1 - 9.5e-23 80.2 3.3 2.8e-11 43.5 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 KII86717.1 - 4.1e-22 79.5 0.0 2.8e-21 76.8 0.0 2.4 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_6 PF12697.2 KII86717.1 - 9.6e-10 38.7 0.9 3e-07 30.5 0.1 3.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII86717.1 - 8.6e-08 32.0 0.3 0.0029 17.3 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KII86717.1 - 0.00023 20.2 1.0 0.00037 19.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF4351 PF14261.1 KII86717.1 - 0.26 11.1 0.0 0.65 9.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Kinesin PF00225.18 KII86718.1 - 2e-89 299.6 0.0 4.9e-89 298.3 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain XkdW PF09636.5 KII86718.1 - 0.55 10.1 6.0 1.7 8.5 0.3 3.7 3 1 1 4 4 4 0 XkdW protein FMO-like PF00743.14 KII86719.1 - 2.4e-21 75.5 0.0 3.3e-09 35.4 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII86719.1 - 1e-13 51.8 0.0 9.7e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII86719.1 - 2.4e-08 33.8 0.0 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII86719.1 - 6.6e-08 32.6 0.0 0.0056 16.5 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KII86719.1 - 7.5e-07 28.3 0.0 0.0001 21.3 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KII86719.1 - 1.7e-05 23.8 0.6 8.5e-05 21.6 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII86719.1 - 2.9e-05 23.8 0.0 0.00079 19.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KII86719.1 - 0.0021 17.2 0.0 0.0062 15.6 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KII86719.1 - 0.0026 16.8 0.0 0.0082 15.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KII86719.1 - 0.0084 16.5 0.0 2.7 8.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KII86719.1 - 0.011 14.8 1.1 0.012 14.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KII86719.1 - 0.025 13.0 0.0 0.053 11.9 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 KII86720.1 - 3.2e-17 62.2 29.5 3.2e-17 62.2 20.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2569 PF10754.4 KII86720.1 - 1.8 8.7 11.4 0.16 12.1 3.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2569) DUF4407 PF14362.1 KII86720.1 - 3.4 6.5 6.2 8.5 5.2 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GFA PF04828.9 KII86722.1 - 1.4e-11 44.1 0.0 1.4e-11 44.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme BcrAD_BadFG PF01869.15 KII86724.1 - 4.8e-13 49.0 0.0 8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Ion_trans PF00520.26 KII86726.1 - 4.3e-17 62.0 17.1 4.3e-17 62.0 11.8 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KII86726.1 - 1.2e-10 40.9 6.8 1.2e-10 40.9 4.7 2.7 3 1 0 3 3 3 1 Ion channel Lig_chan PF00060.21 KII86726.1 - 0.029 14.0 0.5 0.029 14.0 0.3 2.1 2 1 0 2 2 2 0 Ligand-gated ion channel Ribonuclease_3 PF00636.21 KII86727.1 - 2e-45 153.9 0.0 1.8e-21 76.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KII86727.1 - 1e-25 90.1 0.2 2.4e-12 46.8 0.0 4.2 3 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 KII86727.1 - 4.3e-17 62.1 0.0 9.6e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII86727.1 - 9.1e-15 54.2 0.0 3.7e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KII86727.1 - 3.2e-14 52.4 0.0 8.4e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 KII86727.1 - 1.7e-10 40.9 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Slu7 PF11708.3 KII86727.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Asp PF00026.18 KII86728.1 - 1.1e-54 185.8 16.6 1.6e-54 185.3 11.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII86728.1 - 3.1e-06 27.6 8.2 0.00018 21.9 1.9 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 KII86728.1 - 4.1e-06 26.8 12.3 4.2e-06 26.7 6.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KII86728.1 - 0.033 13.7 0.2 2.9 7.4 0.1 2.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal RVP PF00077.15 KII86728.1 - 0.043 13.7 1.7 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease GTP_CH_N PF12471.3 KII86729.1 - 3.8e-87 290.9 0.0 5.5e-87 290.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KII86729.1 - 1.1e-14 54.0 0.0 1.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Toxin_51 PF15531.1 KII86730.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 51 VirB8 PF04335.8 KII86730.1 - 3.9 7.0 5.8 9.8 5.6 0.1 2.1 2 0 0 2 2 2 0 VirB8 protein GNAT_acetyltr_2 PF13718.1 KII86732.1 - 1.9e-74 249.2 0.0 3.3e-74 248.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KII86732.1 - 1.2e-66 223.7 0.0 4.2e-66 221.9 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KII86732.1 - 8.2e-39 131.2 0.1 2.2e-38 129.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KII86732.1 - 8.7e-35 118.8 0.8 2.5e-34 117.4 0.6 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KII86732.1 - 0.0012 18.9 0.0 0.018 15.2 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII86732.1 - 0.095 12.7 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.11 KII86733.1 - 1.8e-35 122.2 31.2 1.8e-35 122.2 21.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII86733.1 - 2.4e-34 118.6 23.8 3.9e-34 118.0 16.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KII86733.1 - 0.00029 20.5 0.7 0.41 10.4 0.0 2.5 2 0 0 2 2 2 2 MFS_1 like family DUF1491 PF07372.7 KII86734.1 - 0.036 13.9 0.5 0.83 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) Complex1_LYR PF05347.10 KII86734.1 - 1.8 8.4 8.4 0.44 10.3 0.1 3.3 3 0 0 3 3 3 0 Complex 1 protein (LYR family) adh_short PF00106.20 KII86735.1 - 1.3e-21 77.2 0.2 2e-21 76.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII86735.1 - 1.4e-08 34.6 0.1 2.2e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII86735.1 - 3.3e-08 33.5 0.0 5.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII86735.1 - 2.4e-06 27.7 1.0 5.4e-06 26.5 0.7 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII86735.1 - 0.00056 19.4 0.0 0.00081 18.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KII86735.1 - 0.078 12.7 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KII86735.1 - 0.14 12.2 0.2 0.39 10.8 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 KII86736.1 - 1.4e-14 54.5 0.3 2.5e-14 53.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII86736.1 - 9.8e-11 41.6 0.0 2.1e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KII86736.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF1749 PF08538.5 KII86736.1 - 0.0071 15.2 0.1 2.8 6.7 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1749) PGAP1 PF07819.8 KII86736.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KII86736.1 - 0.026 14.0 0.1 0.052 13.1 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KII86736.1 - 0.045 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 KII86736.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 KII86736.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase PRP1_N PF06424.7 KII86740.1 - 3.4e-50 169.8 7.7 2.3e-49 167.1 2.9 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KII86740.1 - 5.5e-23 79.3 35.8 0.072 13.7 0.3 14.3 6 4 9 15 15 15 8 Tetratricopeptide repeat TPR_16 PF13432.1 KII86740.1 - 7.3e-19 67.9 22.1 1.1e-05 25.9 0.0 9.1 7 1 3 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KII86740.1 - 6.8e-12 45.5 13.8 0.007 16.6 0.1 9.1 6 3 4 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 KII86740.1 - 1.4e-06 27.7 3.1 5 7.2 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII86740.1 - 3.2e-05 24.1 2.9 35 5.1 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 KII86740.1 - 3.3e-05 23.4 3.9 0.074 12.7 0.0 6.4 5 2 3 8 8 8 2 TPR repeat TPR_12 PF13424.1 KII86740.1 - 0.0002 21.2 7.6 0.7 9.8 0.0 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat PGA2 PF07543.7 KII86740.1 - 0.42 10.4 9.4 0.34 10.7 4.9 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 F-box-like PF12937.2 KII86741.1 - 3.3e-06 26.6 0.0 6.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII86741.1 - 8.7e-05 22.0 0.0 0.00023 20.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain bZIP_2 PF07716.10 KII86742.1 - 1.7e-09 37.3 10.2 6e-09 35.5 6.8 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KII86742.1 - 8.7e-06 25.6 9.4 7.2e-05 22.6 6.5 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KII86742.1 - 0.021 15.0 3.4 0.04 14.2 2.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2216 PF10226.4 KII86742.1 - 0.023 14.2 0.6 0.036 13.5 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) PAT1 PF09770.4 KII86742.1 - 0.042 12.1 10.0 0.052 11.8 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TSC22 PF01166.13 KII86742.1 - 0.054 13.4 1.5 0.097 12.6 1.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2205 PF10224.4 KII86742.1 - 0.12 12.0 0.5 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Sugar_tr PF00083.19 KII86743.1 - 2.7e-18 65.8 20.4 2.3e-12 46.2 3.3 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KII86743.1 - 7.4e-15 54.5 46.5 4.9e-09 35.3 10.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily G-patch PF01585.18 KII86744.1 - 1.7e-06 27.7 0.2 3.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 G-patch domain F-box-like PF12937.2 KII86745.1 - 0.0039 16.8 0.2 0.0039 16.8 0.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.28 KII86745.1 - 0.066 13.2 4.9 3.3 8.0 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 KII86745.1 - 0.14 12.2 4.3 50 4.4 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.2 KII86745.1 - 1.8 8.3 11.8 8.8 6.0 1.1 4.7 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) PQ-loop PF04193.9 KII86746.1 - 1e-32 111.4 9.0 3.7e-19 68.0 2.2 2.9 4 0 0 4 4 4 2 PQ loop repeat PQ-loop PF04193.9 KII86747.1 - 5.2e-33 112.3 10.9 1.1e-18 66.5 1.4 3.2 4 0 0 4 4 4 2 PQ loop repeat NfeD PF01957.13 KII86747.1 - 1.8 8.7 5.0 31 4.6 0.0 3.2 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding Band_7 PF01145.20 KII86748.1 - 1.1e-21 77.5 1.5 1.6e-21 77.0 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_III PF05192.13 KII86749.1 - 3e-35 121.8 0.0 6e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.16 KII86749.1 - 6.9e-34 117.2 0.1 5.6e-24 84.8 0.1 4.2 2 2 0 2 2 2 2 MutS domain V Mito_carr PF00153.22 KII86750.1 - 7.7e-42 140.9 7.7 1.1e-16 60.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 KII86751.1 - 3.1e-70 236.3 0.0 3.9e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86751.1 - 8.5e-32 110.2 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KII86751.1 - 2.1e-09 37.7 1.2 5.8e-09 36.3 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KII86751.1 - 2.3e-05 23.4 0.0 4.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII86751.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII86751.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII86751.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC_membrane PF00664.18 KII86752.1 - 3.2e-95 318.6 27.1 1.3e-47 162.5 6.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII86752.1 - 4.3e-69 231.1 0.1 4e-33 114.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII86752.1 - 2.5e-14 53.9 0.0 6.4e-05 23.0 0.0 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KII86752.1 - 4.8e-14 52.1 3.2 5.5e-05 22.4 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KII86752.1 - 1.3e-10 40.5 1.0 0.00038 19.1 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KII86752.1 - 2.4e-08 33.4 1.1 0.0038 16.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KII86752.1 - 3.6e-08 34.2 0.1 0.0029 18.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KII86752.1 - 1e-06 28.8 2.6 0.0069 16.3 0.1 3.2 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KII86752.1 - 2.6e-05 23.4 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KII86752.1 - 3.8e-05 23.8 3.2 0.16 12.1 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KII86752.1 - 9.3e-05 22.7 0.0 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KII86752.1 - 9.5e-05 22.2 0.0 0.32 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KII86752.1 - 0.00025 20.6 1.9 5.1 6.6 0.0 4.2 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 KII86752.1 - 0.00062 19.6 7.7 0.19 11.6 0.1 3.8 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KII86752.1 - 0.00066 19.4 0.2 1.7 8.3 0.0 3.2 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KII86752.1 - 0.00068 18.4 0.1 0.059 12.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.7 KII86752.1 - 0.00088 18.4 0.0 0.8 8.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KII86752.1 - 0.00092 18.6 3.0 0.46 9.8 0.0 3.5 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 KII86752.1 - 0.007 16.3 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KII86752.1 - 0.0096 15.6 0.1 4.5 6.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) PRK PF00485.13 KII86752.1 - 0.0097 15.4 0.0 0.99 8.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF3987 PF13148.1 KII86752.1 - 0.013 14.1 0.0 0.47 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 KII86752.1 - 0.013 15.4 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KII86752.1 - 0.014 14.8 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KII86752.1 - 0.019 15.3 0.0 6.9 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KII86752.1 - 0.021 13.8 0.0 4.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 KII86752.1 - 0.045 13.5 0.8 12 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KII86752.1 - 0.051 13.0 3.2 5.4 6.3 0.1 3.4 2 1 0 3 3 3 0 AAA-like domain APS_kinase PF01583.15 KII86752.1 - 0.052 13.2 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2628 PF10947.3 KII86752.1 - 0.069 12.9 0.1 0.069 12.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2628) Dynamin_N PF00350.18 KII86752.1 - 0.16 11.7 0.7 11 5.8 0.1 2.8 2 0 0 2 2 2 0 Dynamin family Motile_Sperm PF00635.21 KII86753.1 - 6.8e-27 93.2 0.2 3.2e-26 91.0 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain RICTOR_N PF14664.1 KII86754.1 - 5.8e-92 308.1 0.6 4.2e-90 302.0 0.1 2.3 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KII86754.1 - 1.2e-84 282.8 1.0 2.3e-82 275.3 0.1 3.6 2 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KII86754.1 - 2.5e-32 111.2 0.0 3.7e-31 107.4 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KII86754.1 - 2.2e-28 98.0 0.1 4.2e-26 90.6 0.0 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 KII86754.1 - 0.00013 22.1 0.2 0.36 11.1 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats HR1 PF02185.11 KII86754.1 - 0.00045 19.9 4.1 0.0012 18.5 2.9 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 KII86754.1 - 0.0084 16.1 0.1 14 6.1 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Protoglobin PF11563.3 KII86754.1 - 0.031 13.9 0.5 0.48 10.0 0.1 2.7 2 1 0 2 2 2 0 Protoglobin F-box PF00646.28 KII86756.1 - 0.00028 20.4 0.2 0.00091 18.8 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII86756.1 - 0.00041 20.0 0.1 0.00098 18.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Med18 PF09637.5 KII86756.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Med18 protein ETC_C1_NDUFA4 PF04800.7 KII86758.1 - 7.9e-30 102.7 0.1 1.3e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF221 PF02714.10 KII86759.1 - 5.4e-52 176.6 13.3 8.6e-52 176.0 9.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KII86759.1 - 1.8e-15 56.8 0.8 1.8e-15 56.8 0.5 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KII86759.1 - 4.5e-06 27.0 0.1 0.00013 22.4 0.1 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KII86759.1 - 0.0087 15.9 0.4 0.57 10.1 0.2 2.6 2 0 0 2 2 2 1 Phosphate metabolism protein RRM_5 PF13893.1 KII86759.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII86759.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CBM_1 PF00734.13 KII86760.1 - 1.7e-11 43.5 10.8 1.7e-11 43.5 7.5 2.0 1 1 0 1 1 1 1 Fungal cellulose binding domain C2 PF00168.25 KII86762.1 - 8.7e-10 38.3 0.0 1.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain NACHT PF05729.7 KII86762.1 - 1.5e-05 24.7 0.0 3.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII86762.1 - 9.7e-05 22.4 0.1 0.00065 19.7 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KII86762.1 - 0.00013 20.9 0.0 0.00038 19.4 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 KII86762.1 - 0.059 14.2 0.0 0.23 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.2 KII86763.1 - 1.4e-06 27.8 1.1 2.3e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 F-box-like adh_short PF00106.20 KII86764.1 - 2.8e-22 79.3 0.1 4.3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII86764.1 - 3.6e-12 46.5 0.0 4.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII86764.1 - 1.4e-10 41.1 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.8 KII86764.1 - 0.018 14.4 0.0 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family PIG-L PF02585.12 KII86764.1 - 0.088 13.3 0.1 0.49 10.9 0.1 2.0 2 1 0 2 2 2 0 GlcNAc-PI de-N-acetylase F-box-like PF12937.2 KII86767.1 - 4.1e-07 29.6 0.2 2.7e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII86767.1 - 0.034 13.7 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain CstA PF02554.9 KII86768.1 - 0.014 14.0 2.6 0.017 13.7 1.8 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA 7TMR-DISM_7TM PF07695.6 KII86768.1 - 0.26 10.9 9.1 0.13 11.9 4.6 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling Peptidase_M24 PF00557.19 KII86769.1 - 2.4e-44 151.3 0.0 3.1e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KII86769.1 - 0.00044 20.0 3.7 0.0011 18.8 2.6 1.7 1 0 0 1 1 1 1 MYND finger Sod_Cu PF00080.15 KII86770.1 - 9.4e-44 149.0 0.8 1.2e-43 148.6 0.5 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RskA PF10099.4 KII86770.1 - 0.044 13.5 0.2 0.077 12.7 0.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Arginase PF00491.16 KII86771.1 - 1.9e-79 266.8 0.3 2.3e-79 266.6 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KII86771.1 - 0.0047 17.1 0.1 0.0072 16.5 0.1 1.3 1 0 0 1 1 1 1 UPF0489 domain Ribosomal_L22 PF00237.14 KII86772.1 - 2e-29 101.6 0.1 3.2e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RasGEF PF00617.14 KII86773.1 - 4.7e-12 46.0 0.1 1.1e-11 44.8 0.1 1.6 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII86773.1 - 2.7e-10 40.2 0.0 9.8e-10 38.4 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif HECT PF00632.20 KII86774.1 - 5.4e-91 305.0 0.0 7e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KII86774.1 - 1e-30 105.2 16.2 2.2e-11 43.3 1.3 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KII86774.1 - 1.5e-14 53.5 0.0 3.5e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain Sterol_MT_C PF08498.5 KII86775.1 - 2.8e-27 94.4 0.1 4.5e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 KII86775.1 - 1.3e-18 66.9 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII86775.1 - 6.2e-18 65.0 0.0 1.3e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86775.1 - 8.7e-14 52.0 0.0 2.5e-13 50.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 KII86775.1 - 1.9e-13 50.1 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KII86775.1 - 1.3e-12 48.0 0.0 3.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII86775.1 - 1.3e-12 47.7 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII86775.1 - 1e-11 45.0 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII86775.1 - 1.2e-10 41.3 0.0 3.2e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII86775.1 - 4.7e-09 35.6 0.0 1.1e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KII86775.1 - 5.1e-07 29.2 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KII86775.1 - 2.8e-05 23.7 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 KII86775.1 - 4.6e-05 23.0 0.1 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 KII86775.1 - 0.00068 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.13 KII86775.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 KII86775.1 - 0.0098 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 KII86775.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.13 KII86775.1 - 0.016 14.4 0.1 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.1 KII86775.1 - 0.026 15.3 0.0 0.071 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KII86775.1 - 0.033 13.2 0.0 0.075 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KII86775.1 - 0.048 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.5 KII86775.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Pkinase PF00069.20 KII86777.1 - 3.3e-40 137.8 0.0 4.7e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86777.1 - 2.8e-20 72.5 0.0 3.4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII86777.1 - 0.013 14.5 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 KII86777.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII86777.1 - 0.048 12.4 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KII86777.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Eaf7 PF07904.8 KII86778.1 - 6.9e-12 45.1 0.0 1.1e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Ufd2P_core PF10408.4 KII86779.1 - 9.3e-195 648.5 0.0 1.1e-194 648.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KII86779.1 - 2.3e-29 101.1 1.3 1.4e-28 98.6 0.5 2.6 2 0 0 2 2 2 1 U-box domain Ribosomal_L35p PF01632.14 KII86780.1 - 1.7e-13 50.2 2.4 2.1e-13 49.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 His_Phos_1 PF00300.17 KII86781.1 - 1.3e-29 103.3 0.0 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-AN1 PF01428.11 KII86782.1 - 1.4e-21 76.1 25.9 3.8e-12 45.8 3.3 2.9 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KII86782.1 - 0.092 12.9 19.4 0.45 10.7 2.5 2.7 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain Arginase PF00491.16 KII86784.1 - 5.8e-79 265.2 0.2 7.2e-79 264.9 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KII86784.1 - 0.0031 17.7 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain DUF4436 PF14494.1 KII86785.1 - 5.9e-07 29.0 0.1 8.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Peptidase_S10 PF00450.17 KII86786.1 - 2.4e-79 267.4 1.2 3.4e-79 266.9 0.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FAD_binding_3 PF01494.14 KII86787.1 - 2.7e-74 250.3 0.0 5.4e-74 249.3 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KII86787.1 - 9.6e-07 27.9 0.3 1.6e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KII86787.1 - 4e-06 26.8 0.0 2.2e-05 24.4 0.0 2.3 2 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII86787.1 - 1.7e-05 25.1 0.3 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII86787.1 - 0.00034 19.8 0.1 0.00082 18.5 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII86787.1 - 0.00058 19.8 0.1 0.0016 18.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KII86787.1 - 0.00071 18.1 0.1 0.0022 16.5 0.0 1.8 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 KII86787.1 - 0.0044 15.9 0.1 0.0065 15.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KII86787.1 - 0.015 14.4 0.1 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KII86787.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 KII86788.1 - 5.5e-13 48.4 2.0 1.2e-12 47.2 1.4 1.7 1 0 0 1 1 1 1 F-box-like LigT_PEase PF02834.11 KII86788.1 - 0.019 14.9 0.1 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 LigT like Phosphoesterase FAD_binding_3 PF01494.14 KII86789.1 - 7e-67 225.9 0.0 8.9e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KII86789.1 - 2.1e-08 33.6 0.0 3.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII86789.1 - 8.7e-07 29.2 0.6 0.0022 18.3 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII86789.1 - 9.7e-07 28.8 0.3 5.8e-06 26.3 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII86789.1 - 3e-06 26.3 1.6 3e-06 26.3 1.1 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KII86789.1 - 1.2e-05 24.3 0.8 1.9e-05 23.7 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KII86789.1 - 2.5e-05 22.9 0.6 4.6e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KII86789.1 - 4.1e-05 22.7 0.2 9e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KII86789.1 - 4.5e-05 23.3 0.6 0.00014 21.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII86789.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KII86789.1 - 0.0016 18.5 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KII86789.1 - 0.002 17.1 3.3 0.0029 16.5 0.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII86789.1 - 0.017 14.0 0.6 0.027 13.3 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KII86789.1 - 0.037 12.6 0.7 0.055 12.0 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.16 KII86789.1 - 0.041 13.7 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 KII86789.1 - 0.074 12.7 0.3 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KII86789.1 - 0.078 12.4 1.1 0.17 11.3 0.8 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KII86789.1 - 0.098 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NicO PF03824.11 KII86790.1 - 6.8e-41 140.4 2.4 6.8e-41 140.4 1.7 2.7 2 1 0 2 2 2 1 High-affinity nickel-transport protein PgaD PF13994.1 KII86790.1 - 0.065 12.7 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 PgaD-like protein DER1 PF04511.10 KII86791.1 - 1.7e-46 158.2 5.3 2e-46 157.9 3.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF2839 PF10999.3 KII86791.1 - 0.047 13.7 1.3 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF1625 PF07787.7 KII86791.1 - 0.22 10.7 3.3 0.34 10.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) F-box-like PF12937.2 KII86792.1 - 4.2e-11 42.3 5.9 9.8e-11 41.2 4.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KII86792.1 - 0.061 13.0 1.9 12 5.7 0.2 3.8 3 1 0 3 3 3 0 Leucine rich repeat 4HBT PF03061.17 KII86793.1 - 2.4e-13 50.0 0.7 3.7e-13 49.3 0.5 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KII86793.1 - 0.00011 22.1 0.1 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 KII86793.1 - 0.00062 19.5 0.1 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily RNase_H PF00075.19 KII86794.1 - 0.0011 19.3 0.0 0.0012 19.1 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 KII86795.1 - 2.9e-06 26.8 0.0 4.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDK PF00334.14 KII86797.1 - 1e-15 57.6 0.0 2.7e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase Mmp37 PF09139.6 KII86798.1 - 1.3e-103 346.5 0.0 1.5e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 FA_desaturase PF00487.19 KII86799.1 - 5.6e-14 52.1 20.0 5.6e-14 52.1 13.8 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KII86799.1 - 4.7e-13 48.7 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF413 PF04219.7 KII86800.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF ABC_membrane PF00664.18 KII86803.1 - 1.3e-99 333.1 27.9 3.2e-50 171.0 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII86803.1 - 1.6e-67 226.0 0.0 9.4e-33 113.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII86803.1 - 2.5e-13 50.6 0.0 0.0052 16.7 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KII86803.1 - 7.3e-13 48.2 6.8 0.0001 21.6 0.6 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KII86803.1 - 3e-09 35.9 2.7 0.00043 18.9 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KII86803.1 - 5.4e-08 33.6 0.0 0.0046 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII86803.1 - 1.2e-07 31.0 2.4 0.0063 16.0 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KII86803.1 - 1.7e-06 28.1 3.8 0.0045 17.0 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KII86803.1 - 3.8e-05 23.8 1.8 0.085 12.9 0.1 3.6 2 2 0 2 2 2 1 AAA domain DUF258 PF03193.11 KII86803.1 - 4.9e-05 22.5 0.0 0.27 10.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KII86803.1 - 8e-05 22.4 2.5 0.51 10.2 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KII86803.1 - 8.7e-05 22.8 0.0 0.1 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KII86803.1 - 0.00011 21.8 2.2 1.7 8.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KII86803.1 - 0.00012 21.5 0.6 0.67 9.3 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 KII86803.1 - 0.00015 21.7 0.0 0.77 9.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.15 KII86803.1 - 0.00043 19.1 0.0 0.039 12.6 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.7 KII86803.1 - 0.001 18.1 0.0 1.7 7.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 KII86803.1 - 0.0032 17.1 0.4 1.7 8.3 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KII86803.1 - 0.0037 16.9 0.0 3.2 7.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KII86803.1 - 0.0056 16.6 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KII86803.1 - 0.0058 16.1 0.0 0.71 9.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 KII86803.1 - 0.014 14.9 0.1 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KII86803.1 - 0.014 15.2 0.0 3 7.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 KII86803.1 - 0.016 14.3 0.0 2.2 7.4 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 KII86803.1 - 0.029 14.1 0.8 10 5.8 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KII86803.1 - 0.034 13.5 2.4 5.2 6.4 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain APS_kinase PF01583.15 KII86803.1 - 0.039 13.6 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KII86803.1 - 0.04 13.8 0.0 4.7 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 KII86803.1 - 0.079 11.5 0.0 2.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_23 PF13476.1 KII86803.1 - 0.093 13.0 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KII86803.1 - 0.1 12.7 0.0 11 6.2 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 KII86803.1 - 0.28 9.9 0.1 8.6 5.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KII86803.1 - 0.28 10.1 0.0 7.7 5.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FAD_binding_1 PF00667.15 KII86804.1 - 4.3e-55 186.5 0.0 3.1e-54 183.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KII86804.1 - 1.1e-30 106.5 0.4 1.9e-30 105.7 0.3 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KII86804.1 - 5.2e-21 75.2 0.0 2.1e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KII86804.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain She9_MDM33 PF05546.6 KII86805.1 - 7.6e-75 251.0 9.1 1e-74 250.6 6.3 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Peptidase_S46 PF10459.4 KII86805.1 - 0.052 11.9 5.4 0.053 11.9 3.8 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1414 PF07208.6 KII86805.1 - 0.083 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) DUF445 PF04286.7 KII86805.1 - 0.75 9.2 7.6 1.3 8.4 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1635 PF07795.6 KII86805.1 - 2 7.7 5.0 3 7.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) HIT PF01230.18 KII86806.1 - 3.6e-16 59.4 0.2 5.8e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KII86806.1 - 8.3e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KII86806.1 - 0.0026 17.4 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Na_Ca_ex PF01699.19 KII86807.1 - 3e-25 88.4 30.3 2.9e-14 52.8 5.9 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KII86807.1 - 2.6e-11 43.7 30.1 9.4e-11 41.9 8.3 4.1 3 0 0 3 3 3 2 Domain of unknown function (DUF307) CDC45 PF02724.9 KII86807.1 - 1.8 6.5 8.1 2.5 6.0 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KII86807.1 - 8 4.2 7.6 11 3.7 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family ERG4_ERG24 PF01222.12 KII86809.1 - 8.5e-139 462.7 4.3 9.9e-139 462.5 3.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 KII86809.1 - 4.6e-06 26.6 0.0 4.6e-06 26.6 0.0 2.7 4 0 0 4 4 4 1 Phospholipid methyltransferase DUF1295 PF06966.7 KII86809.1 - 4.7e-06 26.0 0.2 4.7e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KII86809.1 - 0.00016 21.7 0.1 0.0032 17.6 0.0 2.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FANCI_HD1 PF14679.1 KII86809.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 FANCI helical domain 1 Hydrolase_6 PF13344.1 KII86810.1 - 6.6e-13 48.4 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII86810.1 - 2.7e-08 33.3 0.0 5.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KII86810.1 - 0.0057 17.0 0.1 0.069 13.5 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.18 KII86811.1 - 3.5e-23 81.6 1.0 1.5e-22 79.5 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KII86811.1 - 0.0003 20.6 0.1 0.00089 19.1 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Nop PF01798.13 KII86814.1 - 4.9e-58 194.6 0.0 1.1e-57 193.6 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KII86814.1 - 8.4e-27 92.7 0.1 1.9e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KII86814.1 - 8.1e-22 77.1 0.8 8.1e-22 77.1 0.6 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HTH_5 PF01022.15 KII86814.1 - 0.055 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Glyco_hydro_15 PF00723.16 KII86815.1 - 2.3e-96 323.1 1.0 2.6e-96 322.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KII86815.1 - 4.7e-31 106.2 1.3 1e-30 105.2 0.9 1.6 1 0 0 1 1 1 1 Starch binding domain peroxidase PF00141.18 KII86816.1 - 3.4e-33 115.0 0.0 4.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KII86816.1 - 4.6e-16 58.4 0.0 1.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) zf-MYND PF01753.13 KII86817.1 - 5.9e-08 32.4 8.0 2.4e-07 30.5 5.5 2.2 1 1 0 1 1 1 1 MYND finger YjeF_N PF03853.10 KII86818.1 - 1.5e-39 135.2 0.0 1.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 KII86818.1 - 0.056 12.6 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme HAD_2 PF13419.1 KII86822.1 - 2.9e-14 53.6 0.0 1.7e-09 38.1 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII86822.1 - 7.7e-13 49.3 0.0 4.2e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII86822.1 - 4.3e-08 32.7 0.0 9.3e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KII86822.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 KII86823.1 - 6.7e-43 146.2 0.0 3.1e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII86823.1 - 2.4e-37 128.8 31.1 3.5e-21 75.8 3.9 3.6 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 KII86823.1 - 2.4e-11 43.2 0.4 0.011 14.9 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KII86823.1 - 1.7e-07 30.8 0.0 0.021 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KII86823.1 - 1.5e-06 28.4 1.3 1.4 8.8 0.0 4.5 3 2 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KII86823.1 - 5.3e-06 26.9 0.1 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII86823.1 - 7.3e-06 25.4 0.1 0.07 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KII86823.1 - 1.8e-05 24.8 0.6 0.0085 16.0 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KII86823.1 - 5.5e-05 22.1 0.0 0.0051 15.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KII86823.1 - 0.00017 21.1 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 KII86823.1 - 0.00092 18.9 0.5 0.35 10.5 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KII86823.1 - 0.0011 19.0 0.3 1.2 9.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KII86823.1 - 0.0015 18.4 0.2 0.042 13.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 KII86823.1 - 0.0015 17.2 0.2 0.0082 14.8 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_17 PF13207.1 KII86823.1 - 0.0018 19.1 0.0 4.4 8.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KII86823.1 - 0.011 15.4 0.1 0.39 10.4 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain DUF258 PF03193.11 KII86823.1 - 0.011 14.8 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KII86823.1 - 0.013 15.8 0.0 6.7 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KII86823.1 - 0.015 15.1 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 KII86823.1 - 0.036 13.4 1.9 2.1 7.7 0.1 2.7 2 1 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 KII86823.1 - 0.064 13.4 0.1 17 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 KII86823.1 - 0.084 12.8 1.0 0.54 10.2 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.7 KII86823.1 - 0.087 12.1 0.4 8.1 5.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.4 KII86823.1 - 0.097 11.2 0.2 9.9 4.6 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 KII86823.1 - 0.19 11.4 2.9 5.2 6.7 0.1 2.8 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.1 KII86823.1 - 0.21 11.1 0.0 0.5 9.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Oxidored_FMN PF00724.15 KII86825.1 - 7.2e-73 245.5 0.0 8.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.8 KII86825.1 - 0.016 14.6 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) F-box PF00646.28 KII86827.1 - 8e-05 22.1 0.7 0.00026 20.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII86827.1 - 0.0072 16.0 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII86828.1 - 3.3e-05 23.5 0.1 0.00016 21.3 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII86829.1 - 2.8e-05 23.7 0.1 8e-05 22.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like BTB PF00651.26 KII86832.1 - 0.0046 16.9 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Endonuclease_7 PF02945.10 KII86833.1 - 0.074 12.7 1.1 0.1 12.3 0.8 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII BTB PF00651.26 KII86834.1 - 7.8e-06 25.8 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain RR_TM4-6 PF06459.7 KII86834.1 - 0.094 12.5 7.6 0.13 12.1 5.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 KII86834.1 - 0.38 10.2 12.2 0.58 9.6 8.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 KII86834.1 - 0.49 9.0 17.4 0.72 8.5 12.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Silic_transp PF03842.8 KII86834.1 - 5.9 4.8 4.9 8.1 4.3 3.4 1.1 1 0 0 1 1 1 0 Silicon transporter BTB PF00651.26 KII86835.1 - 5e-06 26.4 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF PF02969.12 KII86836.1 - 5.6e-25 87.0 0.1 9.4e-25 86.3 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 KII86836.1 - 6.1e-16 58.3 0.1 1.8e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 KII86836.1 - 0.00016 21.7 0.0 0.00068 19.7 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KII86836.1 - 0.027 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 KII86836.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RIX1 PF08167.7 KII86836.1 - 0.16 11.5 3.0 0.065 12.9 0.4 1.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 KII86836.1 - 0.41 11.1 3.5 9.8 6.8 0.0 4.0 2 1 2 4 4 4 0 HEAT-like repeat CBM_20 PF00686.14 KII86837.1 - 2.7e-25 87.7 0.6 2.7e-25 87.7 0.4 2.3 2 1 0 2 2 2 1 Starch binding domain Peptidase_S64 PF08192.6 KII86837.1 - 0.48 8.6 23.8 0.5 8.6 16.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 SAPS PF04499.10 KII86837.1 - 2.1 6.8 7.7 3 6.3 5.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.8 KII86837.1 - 2.9 7.7 14.4 3.1 7.5 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF936 PF06075.7 KII86837.1 - 4.5 6.0 26.4 5.3 5.8 18.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SOBP PF15279.1 KII86837.1 - 5.1 7.3 19.5 6.5 7.0 13.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Alpha-amylase PF00128.19 KII86838.1 - 1.5e-17 63.9 0.2 3.5e-17 62.7 0.1 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KII86838.1 - 6.1e-09 35.9 0.0 1.9e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Abhydrolase_6 PF12697.2 KII86842.1 - 3.3e-14 53.3 1.0 3.3e-14 53.3 0.7 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII86842.1 - 7.2e-05 22.5 0.0 0.00029 20.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KII86842.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Aldo_ket_red PF00248.16 KII86843.1 - 2.5e-72 243.1 0.0 2.8e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.21 KII86843.1 - 0.047 13.2 0.5 0.83 9.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F-box-like PF12937.2 KII86844.1 - 0.0011 18.6 0.9 0.0023 17.6 0.7 1.5 1 0 0 1 1 1 1 F-box-like HMG_box PF00505.14 KII86845.1 - 3e-15 56.2 0.1 5.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII86845.1 - 1.3e-13 51.0 0.0 2.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 KII86845.1 - 0.059 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) Sialidase_penC PF12135.3 KII86845.1 - 9.8 5.9 6.8 1.9 8.2 0.7 2.6 3 0 0 3 3 3 0 Sialidase enzyme penultimate C terminal domain QRPTase_N PF02749.11 KII86846.1 - 0.083 12.7 0.6 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain NAD_binding_6 PF08030.7 KII86848.1 - 2.7e-20 72.8 0.0 1.5e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KII86848.1 - 9e-16 58.0 6.7 2.9e-15 56.4 4.6 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KII86848.1 - 1e-12 47.8 0.0 7.2e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Trypan_PARP PF05887.6 KII86848.1 - 1.7 8.4 19.9 0.027 14.2 8.7 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) F-box-like PF12937.2 KII86849.1 - 5.6e-09 35.5 0.7 1.7e-08 34.0 0.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII86849.1 - 0.089 12.4 5.0 0.39 10.3 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII86849.1 - 0.54 10.4 4.7 0.88 9.8 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 KII86849.1 - 0.72 9.6 9.4 1.6 8.5 1.6 4.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KII86849.1 - 0.87 9.8 3.9 16 5.9 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat Gly_transf_sug PF04488.10 KII86850.1 - 0.00014 22.1 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KII86850.1 - 0.17 11.0 0.2 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein zf-CCHC_3 PF13917.1 KII86851.1 - 3.2e-20 71.5 3.9 4.5e-20 71.1 2.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KII86851.1 - 0.0073 15.7 0.3 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KII86851.1 - 0.0097 15.8 1.2 0.015 15.2 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KII86851.1 - 0.14 11.6 0.8 0.25 10.8 0.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C2H2_jaz PF12171.3 KII86852.1 - 8.6e-05 22.5 8.7 0.024 14.7 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII86852.1 - 0.00019 21.4 8.1 0.0092 16.1 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KII86852.1 - 0.0007 19.7 19.8 0.31 11.4 1.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII86852.1 - 0.057 13.7 18.8 1.2 9.5 0.3 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger ATP-synt_C PF00137.16 KII86854.1 - 6.1e-28 96.5 31.4 8.6e-17 60.8 6.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L6 PF00347.18 KII86855.1 - 4.7e-21 75.0 0.0 9.6e-13 48.4 0.0 2.5 3 0 0 3 3 3 2 Ribosomal protein L6 tRNA_bind PF01588.15 KII86856.1 - 8.7e-29 99.2 0.0 1.5e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KII86856.1 - 1.9e-05 25.0 0.0 6.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII86856.1 - 0.00092 19.1 0.3 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII86856.1 - 0.012 15.4 0.4 0.064 13.1 0.2 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.16 KII86858.1 - 4e-05 22.5 0.0 4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2387 PF09526.5 KII86859.1 - 0.6 10.0 2.9 0.49 10.3 0.5 1.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) HSP20 PF00011.16 KII86861.1 - 3e-13 49.4 0.0 2.4e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Aldo_ket_red PF00248.16 KII86862.1 - 3.4e-51 173.7 0.0 4.2e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.1 KII86863.1 - 3.4e-24 85.6 0.0 5.3e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII86863.1 - 2.4e-10 40.6 0.0 5.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFA PF04828.9 KII86864.1 - 5.7e-22 77.4 0.6 9.9e-22 76.6 0.4 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 KII86864.1 - 0.01 15.5 0.1 0.01 15.5 0.1 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 KII86865.1 - 2.7e-21 75.3 0.8 3.7e-21 74.8 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 KII86865.1 - 0.0057 16.3 0.1 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 KII86865.1 - 0.14 11.9 2.6 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FerA PF08165.6 KII86865.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 FerA (NUC095) domain CBFD_NFYB_HMF PF00808.18 KII86866.1 - 6.8e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SEN1_N PF12726.2 KII86867.1 - 7.6e-130 434.2 0.0 1.1e-129 433.6 0.0 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KII86867.1 - 1.8e-66 224.0 1.4 1.8e-66 224.0 1.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KII86867.1 - 2.4e-58 196.8 0.0 5.4e-58 195.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII86867.1 - 1.1e-09 37.8 0.0 3.1e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KII86867.1 - 4.5e-08 32.9 0.0 0.00013 21.5 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KII86867.1 - 3e-05 24.1 0.1 0.0003 20.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KII86867.1 - 4.8e-05 22.9 0.0 0.97 8.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KII86867.1 - 0.017 14.5 0.1 0.066 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KII86867.1 - 0.047 13.9 2.0 0.26 11.5 1.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) OB_NTP_bind PF07717.11 KII86868.1 - 1.8e-21 76.0 0.0 4.8e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KII86868.1 - 1.8e-19 69.6 1.5 3.5e-19 68.7 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KII86868.1 - 1.6e-13 50.3 0.0 5.5e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII86868.1 - 8.8e-07 28.5 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII86868.1 - 2e-06 27.9 0.0 6.3e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KII86868.1 - 0.011 16.0 5.4 0.76 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KII86868.1 - 0.016 14.1 0.0 0.04 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KII86868.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF1325 PF07039.6 KII86869.1 - 3.4e-33 114.0 0.0 5.1e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 KII86869.1 - 0.58 10.3 2.7 4.2 7.5 0.0 3.0 3 1 0 3 3 3 0 Agenet domain HSP20 PF00011.16 KII86870.1 - 8.2e-14 51.3 0.2 3.1e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Hsp20/alpha crystallin family Translin PF01997.11 KII86871.1 - 9.9e-45 152.6 0.0 1.1e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Translin family Tail_P2_I PF09684.5 KII86871.1 - 0.1 12.1 0.0 0.82 9.2 0.0 2.3 2 1 1 3 3 3 0 Phage tail protein (Tail_P2_I) Fcf2 PF08698.6 KII86872.1 - 3e-20 72.0 0.0 5.9e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing AF-4 PF05110.8 KII86872.1 - 0.067 11.0 15.8 0.12 10.1 11.0 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein YTH PF04146.10 KII86873.1 - 1.7e-49 167.0 0.0 3.2e-49 166.1 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KII86873.1 - 0.0001 21.8 0.0 0.052 13.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII86873.1 - 0.0029 17.5 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII86873.1 - 0.0045 16.8 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_71 PF03659.9 KII86874.1 - 3.5e-93 312.1 6.9 4.5e-93 311.7 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 KAT11 PF08214.6 KII86876.1 - 8.3e-42 143.4 0.0 1.2e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein SH3_9 PF14604.1 KII86877.1 - 8.3e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII86877.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Sugar_tr PF00083.19 KII86878.1 - 6.5e-84 282.0 21.7 7.4e-84 281.9 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII86878.1 - 2.2e-29 102.2 44.9 2.8e-24 85.4 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII86878.1 - 0.00014 20.4 2.3 0.00014 20.4 1.6 3.3 3 1 0 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 KII86878.1 - 0.046 13.5 8.3 0.91 9.3 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family ADH_zinc_N PF00107.21 KII86879.1 - 3.1e-10 39.6 1.1 5.8e-10 38.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII86879.1 - 3.6e-06 26.6 0.0 8.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII86879.1 - 2.9e-05 24.9 0.3 7.4e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase McyA_C PF12593.3 KII86879.1 - 0.023 14.4 0.2 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal Cullin PF00888.17 KII86882.1 - 2.9e-189 630.4 15.6 4e-189 629.9 10.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KII86882.1 - 1.4e-27 95.3 3.0 4.7e-27 93.5 2.1 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.5 KII86882.1 - 0.019 14.5 0.0 0.071 12.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Rrf2 PF02082.15 KII86882.1 - 0.034 14.2 0.7 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.2 KII86882.1 - 0.037 13.7 0.1 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 MarR family DUF4170 PF13773.1 KII86882.1 - 0.094 12.6 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Ubie_methyltran PF01209.13 KII86883.1 - 6.9e-78 260.9 0.0 1.5e-77 259.8 0.0 1.4 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KII86883.1 - 1.6e-13 50.5 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII86883.1 - 3.7e-11 43.0 0.0 5.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII86883.1 - 1.1e-10 41.8 0.0 2.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII86883.1 - 4.1e-10 39.9 0.0 7.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII86883.1 - 4.4e-09 36.7 0.0 8.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII86883.1 - 4e-06 27.3 0.0 8.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII86883.1 - 0.0017 18.3 0.0 0.0044 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ATE_N PF04376.8 KII86883.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus MRP-L20 PF12824.2 KII86884.1 - 5.8e-24 84.9 0.3 6.5e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KII86884.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Neugrin FAM47 PF14642.1 KII86884.1 - 0.54 9.5 7.9 0.57 9.4 5.0 1.3 1 1 0 1 1 1 0 FAM47 family Malic_M PF03949.10 KII86885.1 - 2.9e-86 289.1 0.0 3.8e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KII86885.1 - 5.4e-63 211.8 0.0 8.2e-63 211.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PH PF00169.24 KII86886.1 - 0.032 14.4 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 PH domain DUF837 PF05769.6 KII86887.1 - 0.0013 18.3 4.4 0.016 14.7 1.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF837) Nsp1_C PF05064.8 KII86887.1 - 0.012 15.2 0.5 0.029 14.0 0.2 1.8 1 1 0 1 1 1 0 Nsp1-like C-terminal region INTS5_N PF14837.1 KII86887.1 - 0.017 14.5 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Ank_5 PF13857.1 KII86890.1 - 7.3e-06 26.0 0.0 0.00047 20.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KII86890.1 - 6.7e-05 22.5 0.0 0.085 12.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KII86890.1 - 0.00034 20.9 0.0 0.0044 17.3 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KII86890.1 - 0.0017 18.3 0.1 4.8 7.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KII86890.1 - 0.041 14.3 0.0 1.1 9.9 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PH PF00169.24 KII86891.1 - 0.0053 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KII86891.1 - 0.0081 16.2 0.1 0.038 14.0 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Nop14 PF04147.7 KII86891.1 - 0.028 12.3 0.2 0.036 12.0 0.1 1.0 1 0 0 1 1 1 0 Nop14-like family PH_11 PF15413.1 KII86891.1 - 0.08 13.1 0.3 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain C2 PF00168.25 KII86892.1 - 4.2e-16 58.5 0.1 3.9e-09 36.2 0.0 3.1 3 0 0 3 3 3 2 C2 domain PHD PF00628.24 KII86893.1 - 0.0048 16.5 6.7 0.012 15.2 4.6 1.7 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KII86893.1 - 0.057 13.1 5.3 0.11 12.2 3.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 KII86893.1 - 0.086 12.5 4.5 0.18 11.5 2.3 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.1 KII86893.1 - 0.12 12.1 3.7 0.2 11.3 2.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AA_permease_2 PF13520.1 KII86894.1 - 2.6e-45 154.7 52.4 3.3e-45 154.3 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII86894.1 - 8.8e-25 86.9 41.5 1.2e-24 86.5 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease F-actin_cap_A PF01267.12 KII86895.1 - 5.3e-93 311.0 0.0 6e-93 310.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF3647 PF12363.3 KII86895.1 - 0.064 13.3 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Phage protein ICL PF00463.16 KII86897.1 - 5.9e-246 816.7 0.4 6.7e-246 816.5 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KII86897.1 - 5.2e-09 35.6 0.0 9.8e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KII86897.1 - 0.011 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Glycos_transf_4 PF00953.16 KII86898.1 - 1.8e-31 109.0 7.6 1.8e-31 109.0 5.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 SET PF00856.23 KII86899.1 - 1.1e-12 48.5 0.1 2e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 KII86900.1 - 9.9e-08 31.5 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Neogenin_C PF06583.7 KII86900.1 - 0.012 15.1 0.5 0.016 14.7 0.4 1.2 1 0 0 1 1 1 0 Neogenin C-terminus Bd3614-deam PF14439.1 KII86900.1 - 0.065 13.0 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase ECH PF00378.15 KII86905.1 - 3.2e-28 98.4 0.0 4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2781 PF10914.3 KII86906.1 - 7.3e-34 116.7 9.0 8.9e-34 116.4 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) PROCN PF08083.6 KII86907.1 - 1.2e-217 722.1 8.9 1.2e-216 718.9 5.7 2.2 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KII86907.1 - 1.1e-126 420.8 0.5 1.9e-126 420.0 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KII86907.1 - 2.2e-92 306.6 1.2 5.6e-92 305.3 0.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KII86907.1 - 2.3e-80 267.5 2.2 2.3e-80 267.5 1.5 2.6 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KII86907.1 - 3.2e-69 230.7 0.1 6.1e-69 229.8 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KII86907.1 - 2.6e-43 145.7 0.2 5.9e-43 144.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KII86907.1 - 1.6e-35 121.5 0.0 3.3e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 KII86907.1 - 0.00024 20.8 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SMC_N PF02463.14 KII86908.1 - 2.1e-27 95.7 0.0 3.9e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KII86908.1 - 8.8e-18 65.3 11.1 8.8e-18 65.3 7.7 5.1 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.1 KII86908.1 - 2e-06 27.1 0.3 2e-06 27.1 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KII86908.1 - 1e-05 25.6 0.8 0.002 18.1 0.3 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KII86908.1 - 9.2e-05 21.8 0.0 0.0003 20.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KII86908.1 - 0.077 13.2 0.1 0.077 13.2 0.1 5.2 3 2 0 3 3 3 0 ABC transporter DUF3584 PF12128.3 KII86908.1 - 0.52 7.5 74.7 0.14 9.4 21.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 KII86908.1 - 4.3 4.8 75.3 2.6 5.6 23.5 2.4 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.1 KII86910.1 - 2.5e-14 53.2 0.0 5.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII86910.1 - 4.8e-10 39.2 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII86910.1 - 7.9e-06 25.6 0.0 2.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII86910.1 - 0.00074 19.4 0.0 0.0032 17.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII86910.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain IF4E PF01652.13 KII86910.1 - 0.014 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E GST_C_3 PF14497.1 KII86910.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SKN1 PF03935.10 KII86911.1 - 1.8e-202 672.9 8.0 2.2e-202 672.7 5.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GRASP55_65 PF04495.9 KII86912.1 - 2.6e-61 205.6 0.0 5.2e-43 146.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KII86912.1 - 0.0012 18.7 0.0 0.4 10.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Zip PF02535.17 KII86912.1 - 0.0016 17.4 11.0 0.0022 17.0 7.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Macoilin PF09726.4 KII86912.1 - 2.6 6.2 4.5 3.7 5.7 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 KII86912.1 - 4.9 6.9 4.9 8 6.2 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region p450 PF00067.17 KII86913.1 - 1.1e-69 235.1 0.0 1.4e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThiF PF00899.16 KII86914.1 - 3e-19 69.2 0.1 5.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.13 KII86915.1 - 2.3e-23 82.4 0.1 4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII86915.1 - 5.1e-07 29.4 10.5 1.1e-06 28.4 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_3 PF13812.1 KII86916.1 - 0.012 15.8 0.3 7.9 7.0 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 KII86916.1 - 0.022 14.7 0.0 6.1 6.8 0.0 3.7 3 1 1 4 4 4 0 PPR repeat family TPR_14 PF13428.1 KII86916.1 - 0.12 13.0 8.2 5.3 7.9 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Mur_ligase_M PF08245.7 KII86917.1 - 1e-06 28.9 0.0 2.8e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Peptidase_C48 PF02902.14 KII86918.1 - 1.3e-35 123.0 0.1 8e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Dynactin_p62 PF05502.8 KII86919.1 - 2.7e-88 296.8 5.0 2.9e-55 187.9 3.0 2.1 1 1 1 2 2 2 2 Dynactin p62 family Pet127 PF08634.5 KII86920.1 - 2.5e-98 328.5 0.0 4.1e-98 327.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Arf PF00025.16 KII86921.1 - 1e-38 132.3 0.0 1.3e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KII86921.1 - 1.3e-18 66.9 0.0 1.6e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII86921.1 - 7.2e-11 42.6 0.0 1.7e-10 41.4 0.0 1.7 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KII86921.1 - 3.8e-08 32.7 0.0 4.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KII86921.1 - 1e-07 31.3 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KII86921.1 - 6.9e-06 24.9 0.8 8.6e-06 24.6 0.1 1.4 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KII86921.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KII86921.1 - 0.0072 16.1 0.3 0.52 10.1 0.5 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 KII86921.1 - 0.0078 15.6 0.0 0.026 13.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Proteasom_Rpn13 PF04683.8 KII86922.1 - 4.4e-22 77.9 0.0 6.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ECH_C PF13766.1 KII86922.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region MNSV_P7B PF06692.6 KII86922.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF2205 PF10224.4 KII86923.1 - 7e-11 41.5 0.0 8.5e-11 41.2 0.0 1.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 KII86923.1 - 0.011 16.0 0.1 0.012 15.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KII86923.1 - 0.084 12.3 0.1 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator RmuC PF02646.11 KII86923.1 - 0.088 11.6 0.2 0.098 11.4 0.1 1.0 1 0 0 1 1 1 0 RmuC family gpW PF02831.10 KII86923.1 - 0.21 11.1 1.2 0.32 10.5 0.9 1.3 1 1 0 1 1 1 0 gpW DUF4267 PF14087.1 KII86924.1 - 1.3e-26 92.4 2.8 1.5e-26 92.1 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) AMP-binding PF00501.23 KII86925.1 - 2.8e-87 292.8 0.0 3.8e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII86925.1 - 0.0008 20.3 0.0 0.002 19.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_8 PF08022.7 KII86925.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain Ebola_NP PF05505.7 KII86925.1 - 0.75 7.7 1.3 1.2 7.1 0.9 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein F-box-like PF12937.2 KII86926.1 - 0.09 12.5 1.0 0.24 11.1 0.1 2.1 2 0 0 2 2 2 0 F-box-like AAA_23 PF13476.1 KII86927.1 - 2.2e-16 60.8 27.7 2.2e-16 60.8 19.2 7.6 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.1 KII86927.1 - 1.3e-14 54.9 10.6 9.7e-09 35.5 0.6 3.9 3 1 1 4 4 4 2 AAA domain SbcCD_C PF13558.1 KII86927.1 - 5.2e-11 42.3 0.0 2.6e-10 40.0 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KII86927.1 - 5e-10 38.9 0.0 5e-10 38.9 0.0 3.4 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 KII86927.1 - 3.9e-09 35.5 121.6 4e-05 22.3 0.0 7.2 3 1 3 7 7 7 5 AAA domain AAA_15 PF13175.1 KII86927.1 - 1e-07 31.4 0.0 1e-07 31.4 0.0 4.5 3 2 0 3 3 3 1 AAA ATPase domain DUF4164 PF13747.1 KII86927.1 - 0.00058 19.9 1.8 0.00058 19.9 1.3 9.6 6 2 4 10 10 8 1 Domain of unknown function (DUF4164) AAA_29 PF13555.1 KII86927.1 - 0.00079 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.14 KII86927.1 - 0.0026 17.3 16.9 0.0026 17.3 11.7 6.9 3 3 4 7 7 5 1 Ezrin/radixin/moesin family ABC_tran PF00005.22 KII86927.1 - 0.0036 17.5 0.0 0.0036 17.5 0.0 6.4 4 2 1 5 5 4 1 ABC transporter Miro PF08477.8 KII86927.1 - 0.024 15.1 0.8 0.21 12.0 0.0 3.1 2 0 0 2 2 2 0 Miro-like protein DUF1131 PF06572.7 KII86927.1 - 0.034 13.6 0.1 0.1 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) AAA_22 PF13401.1 KII86927.1 - 0.11 12.6 3.0 1.3 9.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 KII86927.1 - 0.68 9.0 37.7 0.095 11.8 0.5 6.6 3 3 3 6 6 6 0 Reovirus sigma C capsid protein Pyridox_oxidase PF01243.15 KII86929.1 - 2.3e-24 85.1 0.0 5.4e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 KII86929.1 - 9.4e-19 66.6 3.1 1.9e-18 65.6 1.2 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 KII86929.1 - 4.9e-06 26.7 0.0 9.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kelch_6 PF13964.1 KII86931.1 - 2.3e-19 68.6 4.4 0.00068 19.7 0.0 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 KII86931.1 - 2.9e-18 65.3 7.7 4.5e-06 26.3 0.0 5.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KII86931.1 - 8e-17 60.5 0.0 0.0011 18.5 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 KII86931.1 - 3.5e-15 55.0 5.2 0.00027 20.5 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KII86931.1 - 1.2e-14 53.8 0.8 0.00037 20.3 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KII86931.1 - 1.7e-12 47.1 5.2 7.2e-06 26.0 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain BTB PF00651.26 KII86931.1 - 0.0074 16.2 0.1 0.96 9.4 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain zf-C3HC4_2 PF13923.1 KII86933.1 - 0.00016 21.6 15.3 0.00016 21.6 10.6 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII86933.1 - 0.00048 19.8 13.7 0.00048 19.8 9.5 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.1 KII86933.1 - 0.0017 18.1 9.0 0.0017 18.1 6.2 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 KII86933.1 - 0.0025 17.4 10.9 0.0025 17.4 7.5 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII86933.1 - 0.0031 17.1 12.0 0.0031 17.1 8.3 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII86933.1 - 2.3 8.3 11.1 0.2 11.7 3.7 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger DUF4233 PF14017.1 KII86935.1 - 2 8.3 11.7 6.6 6.7 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Herpes_LMP1 PF05297.6 KII86935.1 - 3.6 6.4 6.0 0.19 10.6 0.3 1.7 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Pectinesterase PF01095.14 KII86936.1 - 2.1e-34 118.4 0.5 3.5e-29 101.3 0.5 2.1 1 1 0 2 2 2 2 Pectinesterase Syntaxin_2 PF14523.1 KII86937.1 - 2.5e-22 78.8 5.7 8.3e-22 77.1 2.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KII86937.1 - 6.3e-16 57.8 3.5 8.9e-16 57.3 0.6 2.4 2 0 0 2 2 2 1 SNARE domain V-SNARE PF05008.10 KII86937.1 - 0.028 14.5 2.8 1.7 8.8 0.2 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TMPIT PF07851.8 KII86937.1 - 0.034 13.2 2.2 0.51 9.3 0.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF2730 PF10805.3 KII86937.1 - 0.35 10.6 2.6 13 5.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3708 PF12501.3 KII86937.1 - 1.9 8.2 8.6 0.49 10.2 0.5 2.7 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter Fib_alpha PF08702.5 KII86937.1 - 8.6 6.4 8.1 15 5.6 0.6 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family F-box-like PF12937.2 KII86938.1 - 5.7e-05 22.7 0.6 0.00031 20.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 KII86939.1 - 1.1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86939.1 - 5.4e-42 143.6 0.0 7e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII86939.1 - 4.2e-07 29.2 0.0 7e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII86939.1 - 0.00059 19.6 0.2 0.13 11.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KII86939.1 - 0.0034 16.4 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII86939.1 - 0.068 12.5 0.0 0.17 11.1 0.0 1.7 2 1 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 KII86939.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_4 PF08386.5 KII86940.1 - 9.6e-16 57.5 0.0 1.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KII86940.1 - 4.7e-08 33.1 1.2 2.2e-07 30.9 0.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII86940.1 - 4.6e-06 26.3 0.3 4.1e-05 23.2 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M16 PF00675.15 KII86941.1 - 1.5e-55 187.0 0.2 4.7e-55 185.4 0.2 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KII86941.1 - 1.4e-42 145.4 0.0 2.1e-39 135.0 0.0 2.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain zf-Nse PF11789.3 KII86942.1 - 2.7e-16 58.8 0.0 4.6e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DNA_Packaging PF11053.3 KII86942.1 - 0.0029 17.2 0.3 0.0063 16.1 0.1 1.6 1 1 0 1 1 1 1 Terminase DNA packaging enzyme zf-RING_UBOX PF13445.1 KII86942.1 - 0.0057 16.3 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KII86942.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SIR2 PF02146.12 KII86943.1 - 1.1e-59 201.1 0.0 1.4e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Ebp2 PF05890.7 KII86944.1 - 1e-78 264.3 9.9 1.5e-78 263.8 6.8 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Oxidored_molyb PF00174.14 KII86945.1 - 6.5e-48 162.3 0.0 1.1e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KII86945.1 - 1.7e-23 82.7 1.5 2.8e-23 82.0 1.1 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Velvet PF11754.3 KII86946.1 - 7.5e-29 100.7 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.3 KII86947.1 - 7.6e-27 94.2 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Velvet factor adh_short PF00106.20 KII86948.1 - 0.00084 19.2 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sas10 PF09368.5 KII86949.1 - 1.2e-22 79.8 4.1 1.2e-22 79.8 2.9 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KII86949.1 - 4.5e-07 29.9 1.0 1.5e-06 28.3 0.7 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pex14_N PF04695.8 KII86949.1 - 0.54 10.3 7.0 0.46 10.5 0.6 2.9 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asp PF00026.18 KII86951.1 - 2.4e-48 165.0 16.4 4.9e-48 164.0 11.3 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII86951.1 - 0.00041 20.3 9.1 0.0035 17.3 5.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII86951.1 - 0.0083 16.6 10.5 0.045 14.2 1.7 3.1 3 0 0 3 3 3 2 Aspartyl protease RVP PF00077.15 KII86951.1 - 0.028 14.3 1.8 4.6 7.2 0.1 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease TAXi_C PF14541.1 KII86951.1 - 0.88 9.1 3.0 6.8 6.2 0.1 2.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal adh_short PF00106.20 KII86954.1 - 2.2e-24 86.2 0.1 2.9e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII86954.1 - 3e-13 49.8 0.0 3.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII86954.1 - 2.5e-11 43.8 0.0 3.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 KII86954.1 - 0.055 12.8 0.1 0.88 8.9 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family TPP_enzyme_N PF02776.13 KII86955.1 - 9.1e-37 126.1 0.1 1.4e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KII86955.1 - 3.7e-20 72.0 0.0 7.8e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KII86955.1 - 1.8e-14 53.5 0.0 6.6e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FA_desaturase PF00487.19 KII86956.1 - 1.5e-24 86.8 17.2 2.6e-24 86.0 11.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.20 KII86957.1 - 2.8e-21 75.8 0.0 4.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII86957.1 - 3.8e-07 29.4 0.0 3.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2088 PF09861.4 KII86957.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) Oxidored_FMN PF00724.15 KII86958.1 - 3.3e-100 335.3 0.0 3.8e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FA_desaturase PF00487.19 KII86959.1 - 5.9e-25 88.1 19.6 9.1e-25 87.5 13.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Exo_endo_phos PF03372.18 KII86960.1 - 8e-09 35.7 0.2 1.3e-08 35.0 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KII86960.1 - 7.9e-07 28.7 1.6 8.8e-05 22.0 0.3 2.7 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Fe-ADH_2 PF13685.1 KII86960.1 - 0.0011 18.3 1.2 0.0022 17.3 0.9 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ABC_membrane PF00664.18 KII86961.1 - 5.4e-46 157.2 24.4 3e-26 92.4 0.8 3.6 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 KII86961.1 - 9.5e-44 149.0 0.0 6.6e-26 91.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII86961.1 - 3.6e-11 42.7 2.1 0.026 13.7 0.0 4.3 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KII86961.1 - 1.6e-08 34.2 0.0 0.001 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KII86961.1 - 1.7e-08 34.8 0.6 0.15 11.9 0.1 4.0 2 2 1 3 3 3 3 AAA domain AAA_23 PF13476.1 KII86961.1 - 2.4e-06 28.0 0.2 0.00027 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KII86961.1 - 3.2e-06 26.2 0.1 0.00072 18.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 KII86961.1 - 3.9e-06 26.2 1.9 0.0087 15.5 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KII86961.1 - 4.9e-06 26.6 2.6 0.01 15.8 0.4 2.5 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KII86961.1 - 1.2e-05 24.9 0.4 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 KII86961.1 - 2.7e-05 23.0 0.1 0.00015 20.5 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_17 PF13207.1 KII86961.1 - 3.3e-05 24.6 0.1 0.12 13.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KII86961.1 - 0.00047 20.4 0.3 0.15 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KII86961.1 - 0.00049 19.8 1.0 1.1 9.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KII86961.1 - 0.00098 19.2 0.8 0.38 10.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KII86961.1 - 0.0019 18.0 1.5 0.11 12.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KII86961.1 - 0.0027 17.4 0.1 0.13 11.9 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_10 PF12846.2 KII86961.1 - 0.01 15.3 1.1 4.2 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KII86961.1 - 0.013 16.0 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KII86961.1 - 0.017 15.0 0.6 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF258 PF03193.11 KII86961.1 - 0.021 14.0 0.1 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KII86961.1 - 0.024 14.3 0.0 0.61 9.7 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase ATP_bind_1 PF03029.12 KII86961.1 - 0.034 13.6 0.3 8.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 KII86961.1 - 0.034 13.6 0.1 11 5.4 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 KII86961.1 - 0.038 13.8 0.0 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 KII86961.1 - 0.051 13.2 0.4 12 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KII86961.1 - 0.055 12.8 0.2 15 4.9 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 KII86961.1 - 0.057 12.9 0.0 8.3 5.8 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KII86961.1 - 0.078 12.6 0.5 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 KII86961.1 - 0.083 12.1 0.8 5.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_14 PF13173.1 KII86961.1 - 0.084 12.7 0.0 0.87 9.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 KII86961.1 - 0.086 12.6 0.8 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 KII86961.1 - 0.11 12.3 0.3 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KII86961.1 - 0.15 11.7 1.8 3.8 7.1 0.1 2.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KII86961.1 - 0.17 12.1 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.4 KII86961.1 - 0.18 10.7 0.0 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 KII86961.1 - 0.3 9.6 1.6 4.6 5.7 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 KII86961.1 - 0.44 9.9 3.9 0.49 9.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain COesterase PF00135.23 KII86963.1 - 1.1e-98 331.2 0.1 1.5e-98 330.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII86963.1 - 9.5e-07 28.6 0.3 3.3e-06 26.8 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII86963.1 - 0.0016 17.7 0.1 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII86963.1 - 0.0048 16.6 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII86963.1 - 0.0095 15.8 0.1 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KII86963.1 - 0.083 12.2 1.6 0.53 9.6 0.1 2.5 3 0 0 3 3 3 0 Putative esterase Macoilin PF09726.4 KII86964.1 - 3.7 5.7 13.0 4.6 5.3 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein BLOC1_2 PF10046.4 KII86966.1 - 0.038 14.1 1.1 0.17 12.0 0.6 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.1 KII86966.1 - 0.067 12.3 0.6 0.091 11.8 0.4 1.1 1 0 0 1 1 1 0 TMCO5 family Filo_VP35 PF02097.10 KII86966.1 - 0.13 11.4 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Filoviridae VP35 NPV_P10 PF05531.7 KII86966.1 - 0.16 12.2 1.4 0.5 10.6 0.4 2.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG5 PF10392.4 KII86966.1 - 0.45 10.4 3.6 2.4 8.1 0.5 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 POP1 PF06978.6 KII86967.1 - 8.9e-49 165.6 14.0 3.7e-27 95.1 0.9 2.6 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KII86967.1 - 4e-28 97.1 0.3 9.2e-28 95.9 0.2 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 KII86967.1 - 0.017 14.4 0.0 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain Abhydrolase_6 PF12697.2 KII86968.1 - 2.4e-05 24.3 0.2 2.8e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Prok-RING_4 PF14447.1 KII86968.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Iso_dh PF00180.15 KII86969.1 - 9e-88 294.5 0.0 1e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S5_C PF03719.10 KII86969.1 - 0.025 13.8 0.1 0.049 12.9 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Glyco_transf_28 PF03033.15 KII86970.1 - 1.6e-23 82.9 0.0 3.3e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KII86970.1 - 2.8e-06 26.1 0.0 5.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 KII86970.1 - 8e-05 22.7 0.0 0.0022 18.1 0.0 2.9 3 0 0 3 3 3 1 PH domain GRAM PF02893.15 KII86970.1 - 0.0044 16.4 0.0 0.18 11.3 0.0 3.0 3 0 0 3 3 3 1 GRAM domain Oxidored_FMN PF00724.15 KII86971.1 - 3.9e-64 216.8 0.0 5.4e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_S19e PF01090.14 KII86972.1 - 2.3e-56 189.0 0.1 2.7e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Pox_P4B PF03292.9 KII86972.1 - 0.074 10.9 0.7 0.091 10.6 0.5 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein HEAT_2 PF13646.1 KII86972.1 - 0.09 13.0 0.1 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Nucleoplasmin PF03066.10 KII86972.1 - 0.17 11.3 10.9 0.2 11.1 7.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin PPP4R2 PF09184.6 KII86972.1 - 0.68 9.4 11.2 0.84 9.1 7.8 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 KII86972.1 - 1.4 8.1 5.4 1.6 7.9 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 KII86972.1 - 2.6 7.1 7.9 2.8 6.9 5.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 KII86972.1 - 9.5 5.7 15.4 13 5.3 10.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1470 PF07336.6 KII86973.1 - 0.13 12.6 1.4 0.18 12.1 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) Zn_clus PF00172.13 KII86974.1 - 7.1e-07 29.0 8.7 1.5e-06 27.9 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII86974.1 - 0.00048 19.0 0.1 0.0016 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2610 PF11020.3 KII86974.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) ELH PF02323.10 KII86974.1 - 0.082 12.0 0.9 0.15 11.1 0.6 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor Mito_carr PF00153.22 KII86976.1 - 1e-28 98.8 7.4 4.7e-15 55.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KII86977.1 - 2.2e-33 115.2 0.0 3.7e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII86977.1 - 7.4e-10 38.5 10.4 1.8e-09 37.3 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KII86978.1 - 1.8e-34 119.0 34.3 1.8e-34 119.0 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KII86980.1 - 4.2e-61 206.8 0.0 5e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KII86981.1 - 2.2e-06 27.3 1.1 5.1e-06 26.1 0.8 1.7 1 0 0 1 1 1 1 F-box-like GFO_IDH_MocA PF01408.17 KII86983.1 - 3.2e-17 63.1 0.0 7.1e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Acetyltransf_7 PF13508.1 KII86984.1 - 0.0015 18.6 0.0 0.0052 16.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII86984.1 - 0.0054 16.5 0.1 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII86984.1 - 0.044 13.8 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family adh_short PF00106.20 KII86985.1 - 2.9e-19 69.5 0.3 4.5e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII86985.1 - 7.9e-08 32.1 0.1 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII86985.1 - 2.9e-06 27.2 0.0 6.2e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII86985.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII86985.1 - 0.007 16.3 0.5 0.014 15.4 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII86986.1 - 2.7e-21 76.1 0.1 4.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII86986.1 - 6.9e-09 35.6 0.0 9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII86986.1 - 4.7e-08 33.0 0.0 6.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII86986.1 - 0.0011 18.4 0.1 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII86986.1 - 0.027 14.4 0.2 0.12 12.4 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding PrpR_N PF06506.6 KII86986.1 - 0.031 13.6 0.1 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 Propionate catabolism activator DUF4336 PF14234.1 KII86987.1 - 9.7e-15 54.4 0.0 4.1e-09 36.0 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Lactamase_B PF00753.22 KII86988.1 - 3.8e-12 46.2 5.0 5.7e-12 45.6 3.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KII86988.1 - 6.5e-06 25.8 0.2 1.1e-05 25.0 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2975 PF11188.3 KII86989.1 - 2.8 7.6 18.7 8.5 6.0 3.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) adh_short PF00106.20 KII86990.1 - 5.4e-23 81.7 4.3 7.1e-23 81.3 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII86990.1 - 9.2e-16 58.3 0.1 1.1e-15 58.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII86990.1 - 2.1e-07 31.1 1.9 3.2e-07 30.5 1.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII86990.1 - 5.9e-06 25.8 0.3 9.6e-06 25.1 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KII86990.1 - 3.1e-05 23.5 0.5 0.00025 20.5 0.3 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII86990.1 - 0.0064 16.4 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 KII86990.1 - 0.0067 15.7 0.2 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family PAE PF03283.8 KII86990.1 - 0.012 14.3 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase 2-Hacid_dh_C PF02826.14 KII86990.1 - 0.034 13.2 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_28 PF03033.15 KII86990.1 - 0.037 13.8 0.5 0.06 13.1 0.3 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Acyl-CoA_dh_1 PF00441.19 KII86991.1 - 4.5e-41 140.4 4.0 7.7e-41 139.6 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KII86991.1 - 6.1e-26 91.2 0.0 1.3e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KII86991.1 - 1.1e-17 63.2 0.3 2.2e-17 62.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KII86991.1 - 7.3e-16 58.6 1.6 1.1e-15 58.0 0.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.23 KII86993.1 - 3.7e-85 285.8 0.0 4.6e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII86993.1 - 3.2e-14 53.6 2.0 6.5e-14 52.6 0.1 2.4 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain MAF_flag10 PF01973.13 KII86993.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 Phenol_monoox PF04663.7 KII86993.1 - 0.1 12.3 0.6 1.1 9.0 0.4 2.5 1 1 0 1 1 1 0 Phenol hydroxylase conserved region p450 PF00067.17 KII86994.1 - 6.5e-73 245.8 0.0 7.8e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2367 PF10164.4 KII86995.1 - 3e-06 26.9 4.0 3.7e-06 26.7 2.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.4 KII86995.1 - 0.0011 18.7 2.3 0.0015 18.3 1.6 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain ATP1G1_PLM_MAT8 PF02038.11 KII86995.1 - 0.12 11.4 1.3 0.15 11.1 0.9 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family zf-HIT PF04438.11 KII86995.1 - 0.61 9.7 4.5 2.2 7.9 3.1 2.0 1 1 0 1 1 1 0 HIT zinc finger zf-C2HC5 PF06221.8 KII86995.1 - 1.6 8.5 7.4 2.7 7.8 5.1 1.6 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type ADH_zinc_N PF00107.21 KII86996.1 - 1.5e-11 43.9 0.1 2.9e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII86996.1 - 3.8e-07 29.8 2.2 6.9e-06 25.7 0.7 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII86996.1 - 0.00041 21.2 0.2 0.0019 19.0 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.1 KII86997.1 - 4.8e-14 51.9 4.2 7.4e-14 51.3 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII86997.1 - 8.9e-10 38.5 2.0 1.5e-09 37.8 1.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KII86997.1 - 1.1e-08 34.8 3.1 1.8e-08 34.2 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII86997.1 - 1.6e-08 34.0 2.9 2.6e-08 33.3 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII86997.1 - 3.8e-08 32.9 2.7 5.9e-08 32.3 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII86997.1 - 3.9e-07 29.6 1.9 6.1e-07 29.0 1.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII86997.1 - 6.3e-05 22.7 1.4 0.00011 21.9 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KII86997.1 - 0.022 14.3 4.8 0.038 13.5 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KII86997.1 - 0.026 14.5 4.0 0.044 13.8 2.8 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KII86997.1 - 0.034 14.1 2.0 0.059 13.3 1.4 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 KII86997.1 - 0.035 13.8 1.8 0.086 12.5 1.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 KII86997.1 - 1.8 8.3 4.0 2.9 7.6 2.8 1.4 1 0 0 1 1 1 0 PHD-finger ETF PF01012.16 KII86998.1 - 3.2e-36 124.5 0.6 4.4e-36 124.0 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Glyco_hydro_18 PF00704.23 KII86999.1 - 1e-59 202.7 2.0 1.4e-59 202.3 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KII87001.1 - 9.8e-11 41.6 0.4 1.2e-10 41.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GMC_oxred_N PF00732.14 KII87002.1 - 2.3e-59 200.9 0.0 3e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII87002.1 - 2.9e-35 121.6 0.0 5.5e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KII87002.1 - 0.00018 20.5 0.1 0.00095 18.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII87002.1 - 0.00045 19.1 0.4 0.0089 14.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KII87002.1 - 0.00096 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KII87002.1 - 0.0016 18.3 0.1 0.0047 16.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII87002.1 - 0.0054 15.8 0.0 0.57 9.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KII87002.1 - 0.0056 16.5 0.0 0.072 12.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII87002.1 - 0.0056 16.7 0.6 2.4 8.1 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ribosom_S12_S23 PF00164.20 KII87003.1 - 7.7e-44 148.0 5.4 9.7e-44 147.7 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF3186 PF11382.3 KII87003.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) PH_4 PF15404.1 KII87004.1 - 3.3e-32 111.5 0.0 1.3e-19 70.4 0.0 3.3 2 1 1 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 KII87004.1 - 0.039 14.1 0.6 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain AOX PF01786.12 KII87005.1 - 9.1e-86 286.5 0.4 1.4e-85 285.9 0.3 1.3 1 0 0 1 1 1 1 Alternative oxidase ICMT PF04140.9 KII87005.1 - 0.068 13.3 0.2 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family HTH_Tnp_Tc5 PF03221.11 KII87006.1 - 8.7e-12 44.6 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF605 PF04652.11 KII87006.1 - 0.28 10.5 9.0 0.33 10.2 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Lamp PF01299.12 KII87007.1 - 0.12 11.5 3.0 0.17 10.9 2.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF566 PF04484.7 KII87007.1 - 0.77 9.2 14.6 0.98 8.8 10.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Neisseria_TspB PF05616.8 KII87007.1 - 3.4 5.9 10.5 4 5.6 7.3 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein KAR9 PF08580.5 KII87007.1 - 4.3 5.4 9.1 5.2 5.2 6.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF4551 PF15087.1 KII87007.1 - 4.5 5.5 5.7 6 5.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.4 KII87007.1 - 7.7 4.6 11.9 10 4.2 8.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SRP-alpha_N PF04086.8 KII87007.1 - 9 5.5 12.5 13 5.0 8.6 1.3 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2462 PF09495.5 KII87008.1 - 1.5e-18 67.3 11.0 1.8e-18 66.9 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) NAD_binding_10 PF13460.1 KII87009.1 - 6.5e-22 78.4 0.0 1e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII87009.1 - 7.9e-14 51.4 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KII87009.1 - 3.7e-12 45.7 0.0 5.5e-10 38.5 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KII87009.1 - 2.2e-11 43.0 0.0 3.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII87009.1 - 3.9e-11 42.8 0.4 2.1e-10 40.4 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KII87009.1 - 1e-07 31.1 0.5 0.00015 20.7 0.1 2.9 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 KII87009.1 - 0.0007 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KII87009.1 - 0.00081 18.3 0.0 0.0019 17.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KII87009.1 - 0.0074 16.2 0.1 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII87009.1 - 0.028 14.0 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.12 KII87009.1 - 0.071 13.5 0.0 0.43 11.0 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Tom22 PF04281.8 KII87010.1 - 1.4e-40 138.0 0.8 1.6e-40 137.7 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Fungal_trans PF04082.13 KII87011.1 - 1.7e-08 33.6 0.0 2.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII87011.1 - 5.3e-07 29.4 9.5 8.9e-07 28.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SQS_PSY PF00494.14 KII87014.1 - 2.6e-47 161.3 1.1 3e-47 161.1 0.8 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3782 PF12644.2 KII87014.1 - 0.04 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) zf-C2H2_2 PF12756.2 KII87016.1 - 0.076 13.1 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3663 PF12404.3 KII87020.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase zf-MYND PF01753.13 KII87021.1 - 1.8e-10 40.4 4.7 3.2e-10 39.6 3.2 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KII87021.1 - 0.013 14.7 1.0 0.027 13.7 0.7 1.5 1 0 0 1 1 1 0 Life-span regulatory factor ArgJ PF01960.13 KII87022.1 - 1.6e-144 481.0 0.0 1.9e-144 480.8 0.0 1.0 1 0 0 1 1 1 1 ArgJ family DUF2383 PF09537.5 KII87022.1 - 0.011 15.9 0.2 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Ribosomal_L35Ae PF01247.13 KII87023.1 - 4.5e-42 141.7 1.0 5e-42 141.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KII87023.1 - 0.003 17.4 0.1 2.5 8.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain RhoGAP PF00620.22 KII87024.1 - 7.7e-18 64.5 0.0 5.1e-17 61.8 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain IncA PF04156.9 KII87024.1 - 0.17 11.4 13.5 0.066 12.7 6.1 2.2 2 0 0 2 2 2 0 IncA protein Bestrophin PF01062.16 KII87025.1 - 2.8e-47 161.0 0.0 3.8e-29 101.5 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel ADH_zinc_N PF00107.21 KII87026.1 - 4.6e-11 42.3 0.1 9.4e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII87026.1 - 6.6e-08 32.2 0.2 3.4e-06 26.7 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glycos_transf_1 PF00534.15 KII87026.1 - 0.0091 15.4 0.1 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Fe_hyd_lg_C PF02906.9 KII87026.1 - 0.16 11.1 0.0 0.34 10.1 0.0 1.5 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain zf-MYND PF01753.13 KII87027.1 - 1.1e-08 34.8 11.4 2.4e-08 33.7 7.9 1.6 1 0 0 1 1 1 1 MYND finger ATP-synt_E PF05680.7 KII87029.1 - 7.1 6.6 12.1 11 6.0 2.2 2.7 2 0 0 2 2 2 0 ATP synthase E chain adh_short PF00106.20 KII87030.1 - 1.7e-21 76.8 1.5 2.3e-21 76.4 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87030.1 - 6.5e-11 42.2 0.3 8.2e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII87030.1 - 2.5e-10 40.5 0.1 3.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peripla_BP_6 PF13458.1 KII87030.1 - 0.018 14.3 0.8 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein Asp PF00026.18 KII87031.1 - 7.3e-32 110.8 0.0 5.3e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII87031.1 - 1.2e-05 25.6 1.2 0.0012 19.2 0.1 2.7 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KII87031.1 - 0.00029 20.4 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KII87031.1 - 0.003 17.3 0.0 0.86 9.4 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Zn_clus PF00172.13 KII87032.1 - 7.6e-07 28.9 11.8 1.5e-06 27.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC37_N PF03234.9 KII87034.1 - 0.0043 17.3 4.6 0.0043 17.3 3.2 2.8 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding KSR1-SAM PF13543.1 KII87034.1 - 0.0051 16.5 2.8 0.39 10.4 0.3 2.9 3 0 0 3 3 3 1 SAM like domain present in kinase suppressor RAS 1 Flagellin_C PF00700.16 KII87034.1 - 0.0097 16.0 6.5 1.5 9.0 0.1 4.0 3 1 1 4 4 4 2 Bacterial flagellin C-terminal helical region BCDHK_Adom3 PF10436.4 KII87034.1 - 0.021 14.3 0.6 0.043 13.3 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase EzrA PF06160.7 KII87034.1 - 0.061 11.5 9.5 0.21 9.7 1.0 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 KII87034.1 - 0.079 13.3 12.0 4.6 7.6 0.2 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF972) DMPK_coil PF08826.5 KII87034.1 - 0.37 10.7 21.3 0.44 10.4 0.2 4.2 3 1 1 4 4 4 0 DMPK coiled coil domain like AAA_13 PF13166.1 KII87034.1 - 0.97 7.8 7.5 1.8 6.9 1.0 2.3 2 0 0 2 2 2 0 AAA domain Mod_r PF07200.8 KII87034.1 - 4.7 7.1 18.6 2.6 7.9 2.0 3.7 4 1 1 5 5 5 0 Modifier of rudimentary (Mod(r)) protein Sugarporin_N PF11471.3 KII87034.1 - 7.5 6.2 11.0 27 4.5 5.1 3.2 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension APG6 PF04111.7 KII87034.1 - 9 5.2 19.6 1.4 7.8 0.3 3.3 3 1 1 4 4 4 0 Autophagy protein Apg6 Borealin PF10512.4 KII87035.1 - 0.78 9.6 3.2 6.1 6.7 2.2 2.0 1 1 0 1 1 1 0 Cell division cycle-associated protein 8 zf-C2HC5 PF06221.8 KII87036.1 - 1.9e-11 43.5 2.9 2.9e-11 42.9 2.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type GATA PF00320.22 KII87039.1 - 8.1e-09 34.6 4.6 1.6e-08 33.7 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-MYND PF01753.13 KII87041.1 - 3.7e-09 36.2 13.2 7.6e-09 35.3 9.1 1.6 1 0 0 1 1 1 1 MYND finger zf-RanBP PF00641.13 KII87042.1 - 0.82 8.8 4.6 5.7 6.1 0.3 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others UvrD_C_2 PF13538.1 KII87046.1 - 0.047 13.8 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain VWA_3 PF13768.1 KII87048.1 - 3.3e-22 78.8 0.0 6.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KII87048.1 - 1.1e-19 70.2 0.1 1.9e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KII87048.1 - 4.7e-17 62.6 0.4 8.5e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KII87048.1 - 5e-14 52.3 0.0 9.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KII87048.1 - 1.2e-10 40.7 0.0 3.2e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 KII87048.1 - 5.6e-06 25.6 0.0 1.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KII87048.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus CobT_C PF11775.3 KII87048.1 - 0.038 13.4 0.1 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain zf-MYND PF01753.13 KII87049.1 - 1.8e-08 34.1 14.0 3.6e-08 33.1 9.7 1.5 1 0 0 1 1 1 1 MYND finger DUF3302 PF11742.3 KII87053.1 - 0.034 13.9 0.1 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) zf-CCHC PF00098.18 KII87056.1 - 0.00014 21.6 0.5 0.00031 20.5 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KII87056.1 - 3.4 7.4 6.6 1.2 8.8 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle adh_short PF00106.20 KII87061.1 - 6.9e-20 71.6 0.1 1.1e-19 71.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87061.1 - 2.7e-09 36.9 0.0 3.5e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII87061.1 - 3.5e-07 30.2 0.0 4.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII87061.1 - 2.3e-06 27.2 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KII87061.1 - 0.006 15.5 0.0 0.0083 15.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein zf-MYND PF01753.13 KII87065.1 - 9.3e-10 38.2 8.9 2.1e-09 37.0 6.1 1.7 1 0 0 1 1 1 1 MYND finger adh_short PF00106.20 KII87066.1 - 6.1e-21 75.0 2.6 8.6e-21 74.5 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87066.1 - 2.1e-10 40.5 0.8 2.9e-10 40.0 0.6 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII87066.1 - 3.4e-08 33.5 0.0 4.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII87066.1 - 6.3e-05 23.0 1.3 9.9e-05 22.4 0.9 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII87066.1 - 0.011 14.9 0.2 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_tran_WecB PF03808.8 KII87066.1 - 0.027 13.8 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Glyoxalase PF00903.20 KII87066.1 - 0.073 13.0 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TP_methylase PF00590.15 KII87066.1 - 0.08 12.6 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Asp PF00026.18 KII87068.1 - 6.6e-34 117.5 0.0 2.4e-32 112.4 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII87068.1 - 0.00014 22.2 0.6 0.00093 19.6 0.1 2.4 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KII87068.1 - 0.00037 20.0 0.1 0.0091 15.5 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Thiolase_N PF00108.18 KII87071.1 - 3.5e-84 281.8 2.3 3.5e-84 281.8 1.6 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KII87071.1 - 1.7e-44 150.1 0.6 4e-44 148.9 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KII87071.1 - 0.0012 18.4 0.9 1.4 8.5 0.0 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KII87071.1 - 0.0015 18.0 2.4 0.014 14.9 0.8 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 KII87072.1 - 1.1e-23 83.9 1.1 1.5e-23 83.5 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87072.1 - 1.2e-12 47.9 0.3 1.5e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII87072.1 - 4.9e-09 35.9 0.1 6.9e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KII87072.1 - 4e-08 33.3 0.1 4.6e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 KII87072.1 - 0.0091 15.4 0.1 0.15 11.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Met_10 PF02475.11 KII87072.1 - 0.11 12.0 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein TPR_6 PF13174.1 KII87072.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4203 PF13886.1 KII87072.1 - 0.18 11.2 1.2 0.42 10.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) DUF4066 PF13278.1 KII87073.1 - 6.1e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KII87073.1 - 5.1e-16 58.4 0.0 6.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KII87074.1 - 6.2e-20 71.1 0.0 7.3e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KII87074.1 - 5.2e-16 58.4 0.0 6.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Calici_MSP PF05752.6 KII87075.1 - 0.21 11.1 1.2 0.46 10.0 0.1 2.0 2 1 0 2 2 2 0 Calicivirus minor structural protein PX PF00787.19 KII87076.1 - 7.1e-13 48.3 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF4646 PF15496.1 KII87077.1 - 0.0033 17.4 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DnaJ_CXXCXGXG PF00684.14 KII87078.1 - 0.0014 18.5 6.3 0.42 10.6 0.2 2.5 2 0 0 2 2 2 2 DnaJ central domain OrfB_Zn_ribbon PF07282.6 KII87078.1 - 0.24 11.0 2.1 14 5.4 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Pkinase PF00069.20 KII87079.1 - 3.1e-05 23.2 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII87079.1 - 8.7e-05 22.3 0.0 0.018 14.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KII87079.1 - 0.0063 15.5 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KII87079.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DTHCT PF08070.6 KII87081.1 - 0.0093 16.5 0.0 0.012 16.2 0.0 1.1 1 0 0 1 1 1 1 DTHCT (NUC029) region DUF2587 PF10759.4 KII87084.1 - 0.027 13.8 0.2 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Siah-Interact_N PF09032.6 KII87084.1 - 0.081 12.9 0.9 0.1 12.6 0.6 1.2 1 0 0 1 1 1 0 Siah interacting protein, N terminal Antimicrobial18 PF08130.6 KII87084.1 - 0.089 12.6 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Type A lantibiotic family zf-C2H2_jaz PF12171.3 KII87086.1 - 5.9e-10 39.0 2.8 9.3e-10 38.3 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII87086.1 - 0.0024 17.9 1.4 0.0039 17.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KII87086.1 - 0.021 14.9 0.8 0.021 14.9 0.6 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KII87086.1 - 0.051 13.9 0.4 0.12 12.7 0.3 1.7 1 1 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII87086.1 - 0.14 12.5 1.3 0.33 11.4 0.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-MYND PF01753.13 KII87087.1 - 1.6e-10 40.6 14.2 1.6e-10 40.6 9.9 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KII87087.1 - 0.0042 16.9 10.8 0.036 13.9 7.5 2.3 1 1 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF3590 PF12148.3 KII87087.1 - 0.044 13.3 0.1 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3590) zf-HIT PF04438.11 KII87087.1 - 0.99 9.1 6.1 1.8 8.3 4.3 1.5 1 0 0 1 1 1 0 HIT zinc finger Glyco_hydro_3 PF00933.16 KII87088.1 - 5.9e-83 278.2 0.0 8.8e-83 277.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII87088.1 - 5.5e-54 183.0 0.1 5.5e-54 183.0 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII87088.1 - 4.5e-22 77.7 0.0 8.7e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pol_alpha_B_N PF08418.5 KII87088.1 - 8.4 5.8 14.6 15 5.0 10.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NTF2 PF02136.15 KII87089.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Cytochrom_B558a PF05038.8 KII87089.1 - 3.6 7.1 4.5 8.5 5.9 3.1 1.6 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit RVT_1 PF00078.22 KII87090.1 - 2.7e-11 43.2 0.0 5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 KII87091.1 - 7.5e-13 48.0 7.5 6.9e-06 26.0 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII87091.1 - 2.9e-10 39.7 6.6 1.3e-05 25.1 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII87091.1 - 9.4e-07 28.8 2.3 9.4e-07 28.8 1.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain Ogr_Delta PF04606.7 KII87091.1 - 0.0031 17.1 1.0 0.48 10.1 0.2 2.1 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 KII87091.1 - 0.0053 16.6 0.2 0.0053 16.6 0.2 2.7 4 0 0 4 4 4 1 C2H2-type zinc finger CHORD PF04968.7 KII87091.1 - 0.0071 16.5 2.4 0.21 11.8 0.2 2.1 2 0 0 2 2 2 1 CHORD zf-LYAR PF08790.6 KII87091.1 - 0.081 12.6 0.6 5.8 6.7 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 KII87091.1 - 0.42 11.0 3.3 0.74 10.2 2.3 1.4 1 1 0 1 1 1 0 TRAF-type zinc finger zf-UBP PF02148.14 KII87091.1 - 1.4 9.0 7.5 2.9 8.0 0.9 2.1 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein RicinB_lectin_2 PF14200.1 KII87094.1 - 1.2e-16 60.9 1.7 1.2e-16 60.9 1.2 2.4 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KII87094.1 - 0.0014 18.6 8.6 0.016 15.2 1.3 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain F-box-like PF12937.2 KII87095.1 - 0.00072 19.2 0.4 0.0038 16.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII87095.1 - 0.0045 16.6 0.3 0.041 13.5 0.0 2.5 2 0 0 2 2 2 1 F-box domain Anoctamin PF04547.7 KII87096.1 - 3e-93 312.9 0.1 4e-93 312.5 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel adh_short PF00106.20 KII87099.1 - 5.7e-16 58.8 0.6 7.8e-16 58.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87099.1 - 2.6e-08 33.9 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87099.1 - 3e-05 23.7 0.1 3.7e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 KR domain GATA PF00320.22 KII87100.1 - 2.1e-31 106.9 13.8 3.1e-16 58.4 2.4 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KII87100.1 - 7.2e-05 22.0 5.4 0.063 12.6 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 KII87100.1 - 0.043 13.4 3.2 4.5 6.9 0.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Spore_coat_CotO PF14153.1 KII87100.1 - 5.7 6.3 8.7 9.2 5.6 6.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 KII87100.1 - 6.2 4.7 7.1 8.7 4.2 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L37e PF01907.14 KII87101.1 - 3.6e-25 87.5 12.6 6.5e-25 86.6 8.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KII87101.1 - 0.00056 19.6 1.9 0.001 18.8 1.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 KII87101.1 - 0.016 14.8 0.5 0.03 14.0 0.3 1.6 1 1 0 1 1 1 0 SelR domain LIM PF00412.17 KII87101.1 - 0.035 14.1 2.1 0.07 13.2 1.5 1.5 1 0 0 1 1 1 0 LIM domain zf-ribbon_3 PF13248.1 KII87101.1 - 0.49 9.6 3.3 1.5 8.1 2.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KII87101.1 - 0.5 9.9 3.4 2.8 7.5 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF2427 PF10348.4 KII87102.1 - 4.3 6.9 7.7 0.17 11.4 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) VPS9 PF02204.13 KII87103.1 - 5.5e-16 58.4 0.0 8.5e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain adh_short PF00106.20 KII87104.1 - 6e-18 65.3 0.1 9e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87104.1 - 3.2e-07 30.3 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87104.1 - 1e-05 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Pox_TAA1 PF03295.9 KII87104.1 - 0.041 13.5 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal AIRC PF00731.15 KII87104.1 - 0.091 12.0 0.4 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 AIR carboxylase adh_short PF00106.20 KII87105.1 - 2.4e-18 66.6 0.3 3.3e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KII87105.1 - 2e-08 33.9 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KII87105.1 - 4.9e-08 33.0 0.0 6.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87105.1 - 2.1e-06 27.5 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII87105.1 - 0.047 13.7 0.3 0.077 12.9 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 KII87105.1 - 0.11 11.3 0.3 1 8.1 0.2 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain Kinesin PF00225.18 KII87106.1 - 2.8e-76 256.3 0.0 5.2e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Reo_sigmaC PF04582.7 KII87106.1 - 0.00059 19.1 3.9 0.0013 17.9 2.7 1.6 1 1 0 1 1 1 1 Reovirus sigma C capsid protein CENP-Q PF13094.1 KII87106.1 - 0.0059 16.6 0.3 0.0059 16.6 0.2 2.7 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 KII87106.1 - 0.14 11.9 18.1 0.016 14.9 5.4 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 KII87106.1 - 0.15 11.4 16.4 0.3 10.4 11.4 1.5 1 0 0 1 1 1 0 Intermediate filament protein DUF972 PF06156.8 KII87106.1 - 0.16 12.2 14.7 9.8 6.5 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF972) HlyD PF00529.15 KII87106.1 - 0.17 11.1 16.3 0.27 10.4 11.3 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Bacillus_HBL PF05791.6 KII87106.1 - 0.43 9.9 5.2 1.7 7.9 0.3 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Miff PF05644.6 KII87106.1 - 0.6 9.7 9.6 1.2 8.6 6.7 1.5 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff ERM PF00769.14 KII87106.1 - 3.3 7.1 24.7 4.4 6.7 0.6 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.6 KII87106.1 - 4.3 5.8 14.6 1 7.9 2.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Macoilin PF09726.4 KII87106.1 - 4.8 5.3 14.0 8.5 4.5 9.7 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF87 PF01935.12 KII87106.1 - 5.1 6.8 5.6 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 IncA PF04156.9 KII87106.1 - 5.5 6.5 23.1 1.5 8.4 7.6 2.3 1 1 1 2 2 2 0 IncA protein Carla_C4 PF01623.12 KII87109.1 - 0.97 9.2 8.8 0.05 13.3 1.9 2.0 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein Kinesin PF00225.18 KII87111.1 - 8.5e-68 228.5 0.4 8.5e-68 228.5 0.3 2.4 2 1 0 2 2 2 1 Kinesin motor domain Reo_sigmaC PF04582.7 KII87111.1 - 0.0063 15.7 2.1 0.0063 15.7 1.5 2.4 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 KII87111.1 - 0.44 9.8 9.1 2.8 7.2 0.4 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) APG6 PF04111.7 KII87111.1 - 0.59 9.1 17.1 18 4.2 0.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KII87111.1 - 0.65 9.7 24.8 0.077 12.7 5.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 KII87111.1 - 3.4 5.8 22.8 14 3.7 15.8 1.9 1 1 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 KII87111.1 - 4.3 7.1 16.4 7.6 6.3 11.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc7 PF08317.6 KII87111.1 - 4.6 5.8 17.2 0.68 8.5 4.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 KII87111.1 - 5 5.9 16.8 10 4.9 11.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 KII87111.1 - 6.1 6.6 26.7 1.9 8.3 6.6 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_capsid PF06112.6 KII87111.1 - 7.8 6.5 15.2 2.9 7.9 3.7 3.3 4 0 0 4 4 4 0 Gammaherpesvirus capsid protein ADIP PF11559.3 KII87111.1 - 9.1 6.1 30.7 0.21 11.4 6.5 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Kinesin PF00225.18 KII87115.1 - 2e-102 342.3 0.0 3.4e-102 341.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain TPR_MLP1_2 PF07926.7 KII87115.1 - 0.0053 16.5 8.7 0.0053 16.5 6.1 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KII87115.1 - 0.0053 15.9 13.2 0.0088 15.2 3.9 2.6 2 1 0 2 2 2 2 Reovirus sigma C capsid protein Filament PF00038.16 KII87115.1 - 0.016 14.6 17.0 0.03 13.7 11.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 KII87115.1 - 0.078 12.0 15.0 5.3 5.9 0.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 HlyD PF00529.15 KII87115.1 - 0.29 10.3 15.9 0.54 9.5 11.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Miff PF05644.6 KII87115.1 - 0.54 9.8 10.0 1.2 8.6 6.9 1.5 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF972 PF06156.8 KII87115.1 - 1.9 8.8 17.3 20 5.5 0.2 4.6 3 1 0 4 4 4 0 Protein of unknown function (DUF972) Bacillus_HBL PF05791.6 KII87115.1 - 2.2 7.6 6.5 3.7 6.8 0.4 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Macoilin PF09726.4 KII87115.1 - 3 6.0 14.5 6.1 4.9 10.1 1.5 1 0 0 1 1 1 0 Transmembrane protein Spc7 PF08317.6 KII87115.1 - 6.6 5.2 15.8 2.7 6.5 2.7 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein adh_short PF00106.20 KII87116.1 - 5.2e-17 62.2 0.2 7.5e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87116.1 - 5.5e-08 32.8 0.0 6.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87116.1 - 0.00034 20.3 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII87118.1 - 1.2e-16 61.1 3.2 1.2e-16 61.1 2.2 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87118.1 - 3.5e-06 26.9 0.2 4.6e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87118.1 - 4.9e-06 26.3 0.3 6e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII87119.1 - 1.7e-18 67.1 1.7 2.4e-18 66.6 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87119.1 - 3.1e-09 36.9 0.1 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87119.1 - 9.3e-07 28.6 0.5 1.2e-06 28.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII87119.1 - 0.00052 19.5 0.1 0.00075 19.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII87119.1 - 0.077 12.9 1.1 0.17 11.8 0.8 1.5 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KII87120.1 - 6.5e-20 71.7 2.6 6.5e-20 71.7 1.8 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII87120.1 - 2.7e-06 27.1 0.7 3.6e-06 26.7 0.5 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII87121.1 - 8.8e-12 45.2 10.1 1.2e-07 31.7 5.2 3.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87121.1 - 4.7e-05 23.2 0.0 0.00086 19.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87121.1 - 0.0036 16.9 2.2 0.037 13.6 1.5 2.3 1 1 0 1 1 1 1 KR domain Opi1 PF08618.5 KII87122.1 - 1.5e-46 159.2 15.8 1.8e-37 129.2 6.1 4.8 3 2 0 3 3 3 2 Transcription factor Opi1 adh_short PF00106.20 KII87123.1 - 3.4e-17 62.8 2.7 4.9e-17 62.3 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87123.1 - 5.3e-08 32.7 0.8 7.6e-08 32.2 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII87123.1 - 2.2e-05 24.0 0.1 3.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KII87123.1 - 4.5e-05 23.3 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.2 KII87124.1 - 0.00024 20.7 0.0 0.00084 19.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87124.1 - 0.00025 20.6 0.0 0.001 18.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain UQ_con PF00179.21 KII87125.1 - 1.8e-17 63.0 0.0 2e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KII87125.1 - 0.015 15.2 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain VHS PF00790.14 KII87126.1 - 4.5e-30 104.1 0.1 8e-30 103.3 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KII87126.1 - 1.5e-15 56.5 0.2 2.7e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII87126.1 - 3.8e-14 51.8 0.1 6.5e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII87126.1 - 5.3e-14 51.3 0.0 9.5e-14 50.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain GAT PF03127.9 KII87126.1 - 5.8e-06 26.2 1.7 1.7e-05 24.7 1.2 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 KII87126.1 - 0.0054 16.2 1.0 0.0054 16.2 0.7 1.9 2 0 0 2 2 2 1 Ubiquitin interaction motif F-box-like PF12937.2 KII87127.1 - 1.1e-07 31.4 3.2 1e-06 28.3 0.1 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KII87127.1 - 0.056 13.1 1.2 0.14 11.8 0.0 2.3 2 1 0 2 2 2 0 F-box domain UQ_con PF00179.21 KII87129.1 - 2e-23 82.3 0.0 2.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thymidylate_kin PF02223.12 KII87130.1 - 2e-40 138.1 0.0 2.2e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 KII87130.1 - 0.00077 18.7 0.0 0.0026 17.0 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 KII87130.1 - 0.029 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KII87130.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.1 KII87130.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pro_isomerase PF00160.16 KII87131.1 - 4.9e-40 137.2 0.0 1.2e-39 135.9 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SGT1 PF07093.6 KII87131.1 - 0.083 11.2 12.8 0.011 14.1 6.1 1.5 2 0 0 2 2 2 0 SGT1 protein HAUS6_N PF14661.1 KII87132.1 - 9.4e-10 38.2 0.8 1.9e-08 33.9 0.6 2.8 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus FAD_binding_3 PF01494.14 KII87133.1 - 2e-20 73.1 0.5 6.5e-20 71.4 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KII87133.1 - 1e-05 24.6 0.3 1.4e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KII87133.1 - 0.00024 21.0 3.3 0.0007 19.5 2.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII87133.1 - 0.0015 18.4 0.1 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KII87133.1 - 0.0025 16.5 0.2 0.0049 15.5 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 KII87133.1 - 0.03 13.1 0.4 0.038 12.8 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KII87133.1 - 0.043 12.2 3.4 0.059 11.8 2.4 1.1 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KII87133.1 - 0.068 12.0 4.9 0.043 12.7 2.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII87133.1 - 0.076 13.4 3.2 0.21 12.0 2.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII87133.1 - 0.21 10.6 1.9 0.31 10.0 1.3 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KII87134.1 - 8.1e-23 81.0 0.1 8.4e-22 77.6 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KII87134.1 - 9.9e-07 27.7 0.1 2.3e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KII87134.1 - 4.9e-05 23.2 3.4 0.00015 21.7 2.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII87134.1 - 0.0025 16.7 2.9 0.0041 16.0 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII87134.1 - 0.0035 17.2 0.7 0.0059 16.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII87134.1 - 0.011 14.2 0.7 0.018 13.5 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KII87134.1 - 0.021 15.2 1.7 0.021 15.2 1.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII87134.1 - 0.073 11.9 4.7 0.17 10.7 3.3 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KII87134.1 - 0.24 10.2 1.7 0.33 9.7 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Exo_endo_phos PF03372.18 KII87135.1 - 1.1e-14 54.9 0.1 2e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KII87135.1 - 1.8e-09 37.2 0.0 7.4e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KII87135.1 - 1.2e-06 28.2 2.8 6e-05 22.8 0.3 2.5 2 0 0 2 2 2 2 GRF zinc finger CDC27 PF09507.5 KII87135.1 - 1.8 7.6 18.0 5.2 6.1 1.2 2.1 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 Med3 PF11593.3 KII87135.1 - 2.2 7.4 16.4 2.9 7.0 11.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase_Tyr PF07714.12 KII87137.1 - 4.4e-25 88.2 0.0 5e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII87137.1 - 2.2e-23 82.7 0.0 2.6e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII87137.1 - 0.0077 15.2 0.0 0.0088 15.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Myb_DNA-binding PF00249.26 KII87139.1 - 4.2e-05 23.5 0.1 0.0016 18.4 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.20 KII87140.1 - 1.4e-12 47.3 0.1 2.2e-10 40.1 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII87140.1 - 2.4e-07 30.1 0.1 3.6e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII87140.1 - 0.069 12.2 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KII87141.1 - 1.3e-30 106.3 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII87141.1 - 1.7e-27 96.1 0.0 2.2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII87141.1 - 9.5e-05 21.4 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII87141.1 - 0.0069 16.1 0.1 0.018 14.7 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII87141.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HSP20 PF00011.16 KII87142.1 - 3.1e-13 49.4 0.0 3.7e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 KII87142.1 - 0.17 11.5 0.3 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 GvpH F-box-like PF12937.2 KII87147.1 - 0.00022 20.8 0.1 0.00022 20.8 0.1 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KII87147.1 - 0.00095 18.7 0.1 0.003 17.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ribonuc_red_sm PF00268.16 KII87149.1 - 4.1e-102 340.9 0.0 4.8e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Methyltransf_23 PF13489.1 KII87150.1 - 3.1e-19 69.2 0.0 4.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII87150.1 - 3.1e-12 46.8 0.0 5.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII87150.1 - 2.5e-08 33.6 0.0 3.4e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII87150.1 - 1.3e-07 32.1 0.0 1.2e-06 29.0 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII87150.1 - 1.7e-06 28.4 0.0 6.9e-06 26.4 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KII87150.1 - 5.3e-06 25.0 0.0 0.0026 16.1 0.0 2.0 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 KII87150.1 - 5.9e-06 26.5 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KII87150.1 - 0.00022 20.9 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 KII87150.1 - 0.00063 18.9 0.0 0.005 15.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KII87150.1 - 0.0024 16.9 0.0 0.021 13.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KII87150.1 - 0.0051 16.8 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KII87150.1 - 0.0051 16.1 0.0 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KII87150.1 - 0.0084 15.3 0.0 0.046 12.9 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase DUF938 PF06080.7 KII87150.1 - 0.0098 15.4 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 KII87150.1 - 0.016 15.1 0.0 0.17 11.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KII87150.1 - 0.031 13.3 0.0 0.081 11.9 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase F-box PF00646.28 KII87153.1 - 0.066 12.8 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 F-box domain DUF2764 PF10962.3 KII87154.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Skp1 PF01466.14 KII87155.1 - 2.5e-33 113.9 0.1 4.2e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KII87155.1 - 1.8e-15 56.7 0.2 3.1e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBB PF14545.1 KII87155.1 - 0.11 12.0 0.0 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, O-FucT PF10250.4 KII87157.1 - 1.3e-08 34.3 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase XPC-binding PF09280.6 KII87158.1 - 0.031 13.7 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain RhoGEF PF00621.15 KII87159.1 - 3.7e-38 131.1 0.0 5.2e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 KII87159.1 - 2.5e-17 62.4 13.5 4.3e-17 61.7 9.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KII87159.1 - 6.3e-05 23.1 0.0 0.00053 20.1 0.0 2.5 2 1 0 2 2 2 1 PH domain zf-DHHC PF01529.15 KII87159.1 - 0.49 9.7 4.5 0.96 8.8 3.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KII87159.1 - 0.86 9.5 8.4 1.7 8.6 5.9 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger F-box-like PF12937.2 KII87160.1 - 7e-07 28.8 1.0 6.5e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KII87160.1 - 0.086 12.6 0.5 4.3 7.1 0.0 4.0 4 1 1 5 5 5 0 Leucine rich repeat WD40 PF00400.27 KII87161.1 - 1e-86 281.9 25.8 3.2e-12 45.8 0.2 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 KII87161.1 - 1.5e-09 37.7 0.1 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KII87161.1 - 7.4e-06 24.3 7.8 0.057 11.5 0.0 4.4 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII87161.1 - 0.0011 17.8 0.9 2.1 7.0 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Pirin PF02678.11 KII87162.1 - 1.1e-26 92.8 1.0 1.8e-26 92.0 0.7 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KII87162.1 - 5.1e-10 38.7 0.9 6.1e-07 28.8 0.3 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KII87162.1 - 0.18 11.2 1.0 0.89 8.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF861) DUF2263 PF10021.4 KII87163.1 - 3.5e-17 62.7 0.0 5.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SAICAR_synt PF01259.13 KII87164.1 - 4.7e-81 271.5 0.0 6e-67 225.3 0.0 2.0 2 0 0 2 2 2 2 SAICAR synthetase Glyco_hydro_18 PF00704.23 KII87167.1 - 0.043 13.2 0.0 0.052 13.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 RNA_pol_Rpb2_3 PF04565.11 KII87170.1 - 0.078 12.7 0.6 0.078 12.7 0.4 1.9 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 3 Tmemb_170 PF10190.4 KII87172.1 - 0.016 15.2 0.5 0.016 15.2 0.4 1.5 2 0 0 2 2 2 0 Putative transmembrane protein 170 FtsX PF02687.16 KII87172.1 - 9.1 6.0 14.1 2.7 7.7 7.2 1.8 2 0 0 2 2 2 0 FtsX-like permease family WD40 PF00400.27 KII87173.1 - 5.3e-68 222.6 26.5 5.4e-12 45.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KII87173.1 - 9e-10 38.5 0.9 0.00015 21.5 0.0 3.8 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KII87173.1 - 3e-06 25.6 11.0 0.0077 14.4 0.6 4.6 1 1 4 5 5 5 3 Nucleoporin Nup120/160 CDtoxinA PF03498.9 KII87173.1 - 0.0015 17.8 1.2 0.0034 16.7 0.3 1.9 2 1 0 2 2 2 1 Cytolethal distending toxin A/C family Cytochrom_D1 PF02239.11 KII87173.1 - 0.0086 14.4 0.5 0.43 8.8 0.0 2.7 2 1 1 3 3 3 1 Cytochrome D1 heme domain Kelch_6 PF13964.1 KII87173.1 - 0.029 14.5 0.2 1.1 9.5 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Arylsulfotran_2 PF14269.1 KII87173.1 - 0.032 13.3 0.2 0.063 12.4 0.1 1.4 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) IKI3 PF04762.7 KII87173.1 - 0.14 9.9 0.6 2.8 5.6 0.2 2.7 2 1 0 2 2 2 0 IKI3 family DUF3275 PF11679.3 KII87173.1 - 0.39 10.3 3.7 0.64 9.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF4245 PF14030.1 KII87174.1 - 0.028 14.1 0.7 0.045 13.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) NADH-u_ox-rdase PF10785.4 KII87175.1 - 6.1e-31 106.5 0.4 1.6e-30 105.1 0.1 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KII87175.1 - 8.2e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DIOX_N PF14226.1 KII87176.1 - 1.4e-15 57.8 0.0 2.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII87176.1 - 5.1e-13 49.1 0.0 8.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RabGAP-TBC PF00566.13 KII87177.1 - 3.7e-49 167.1 0.0 5.7e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KII87177.1 - 1.4e-05 25.1 1.8 0.0061 16.6 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KII87177.1 - 0.00018 20.5 2.0 0.0015 17.6 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KII87177.1 - 0.0002 20.9 4.4 0.0019 17.9 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KII87177.1 - 0.00091 18.7 3.0 1.1 8.9 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair GRAM PF02893.15 KII87177.1 - 0.0061 16.0 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 GRAM domain MSP1_C PF07462.6 KII87177.1 - 9.4 4.4 8.5 15 3.8 5.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Na_H_Exchanger PF00999.16 KII87178.1 - 1.9e-34 118.8 28.8 1e-33 116.4 19.9 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Nucleos_tra2_N PF01773.15 KII87178.1 - 0.13 12.6 7.1 0.51 10.7 1.4 3.1 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus zf-RanBP PF00641.13 KII87179.1 - 0.0006 18.8 20.4 0.0074 15.3 4.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KII87179.1 - 0.0011 18.4 1.6 0.75 9.4 0.3 2.6 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Prok-RING_2 PF14445.1 KII87179.1 - 0.12 12.2 5.3 0.91 9.5 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Pkinase PF00069.20 KII87180.1 - 1.4e-71 240.7 0.0 1.6e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87180.1 - 6.4e-32 110.6 0.0 1.3e-31 109.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KII87180.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KII87180.1 - 0.055 12.4 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Abhydrolase_6 PF12697.2 KII87181.1 - 3.2e-25 89.3 0.1 5.1e-25 88.6 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87181.1 - 3.6e-11 43.0 0.0 8.1e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII87181.1 - 2e-06 27.6 0.0 7.4e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KII87181.1 - 9.4e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Pneumo_M2 PF07380.6 KII87181.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Pneumovirus M2 protein Hydrolase_4 PF12146.3 KII87181.1 - 0.018 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 KII87181.1 - 0.024 14.0 0.0 0.069 12.5 0.0 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KII87182.1 - 8.3e-26 91.2 0.6 1e-25 90.9 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87182.1 - 6.6e-11 42.1 0.2 1.7e-09 37.5 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII87182.1 - 1e-07 31.7 0.2 3.4e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KII87182.1 - 0.00067 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KII87182.1 - 0.008 16.4 0.4 0.02 15.1 0.0 1.9 2 1 0 2 2 2 1 Thioesterase domain Pneumo_M2 PF07380.6 KII87182.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus M2 protein DnaJ PF00226.26 KII87183.1 - 2.6e-15 55.9 0.4 4.3e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain FUSC PF04632.7 KII87183.1 - 1.1 7.6 12.1 1.2 7.4 8.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SusD PF07980.6 KII87183.1 - 5.6 6.3 9.6 7.1 6.0 6.6 1.3 1 1 0 1 1 1 0 SusD family OHCU_decarbox PF09349.5 KII87184.1 - 9.8e-32 110.4 0.0 1.5e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 OHCU decarboxylase GFO_IDH_MocA PF01408.17 KII87185.1 - 1.5e-21 77.1 0.1 2.3e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KII87185.1 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3328 PF11807.3 KII87186.1 - 8.7e-17 61.5 0.2 1.2e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YlaH PF14036.1 KII87187.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 YlaH-like protein DUF3328 PF11807.3 KII87188.1 - 1.3e-19 70.7 5.2 3.1e-19 69.5 3.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) zf-RING_2 PF13639.1 KII87191.1 - 1.4e-09 37.5 7.6 4.6e-09 35.9 5.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-CCCH PF00642.19 KII87191.1 - 2.3e-09 36.7 27.0 8.7e-05 22.0 3.5 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KII87191.1 - 3.8e-09 36.0 6.7 1.2e-08 34.4 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII87191.1 - 9.6e-09 34.7 7.5 3.1e-08 33.1 5.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII87191.1 - 1.2e-06 28.4 9.0 1.2e-06 28.4 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII87191.1 - 2.1e-05 24.1 6.4 7.2e-05 22.4 4.5 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KII87191.1 - 0.00075 19.5 8.0 0.012 15.6 5.5 2.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KII87191.1 - 0.017 14.8 3.1 0.023 14.3 1.5 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KII87191.1 - 0.018 14.9 9.0 0.087 12.7 6.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KII87191.1 - 0.49 10.2 7.6 2.1 8.1 5.2 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein SAGA-Tad1 PF12767.2 KII87194.1 - 2.4e-35 122.4 0.0 4.1e-35 121.6 0.0 1.4 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 KII87194.1 - 0.026 13.7 0.2 0.042 13.1 0.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.8 KII87195.1 - 3.9e-27 93.8 0.0 5.6e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 KII87195.1 - 0.021 14.5 0.1 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated Ribosomal_60s PF00428.14 KII87195.1 - 0.025 14.9 6.4 0.32 11.4 0.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Birna_VP4 PF01768.11 KII87195.1 - 0.043 12.8 0.9 0.15 11.0 0.2 1.9 2 0 0 2 2 2 0 Birnavirus VP4 protein WD40 PF00400.27 KII87196.1 - 2.7e-16 58.7 6.4 0.00038 20.2 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KII87196.1 - 6.9e-05 21.7 0.3 0.0064 15.2 0.0 2.9 1 1 1 3 3 3 1 Nup133 N terminal like DUF1192 PF06698.6 KII87196.1 - 0.0078 16.0 0.3 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DnaJ PF00226.26 KII87197.1 - 8.9e-21 73.3 0.1 1.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KII87198.1 - 3.2e-14 52.4 1.0 1.2e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII87198.1 - 3.6e-05 23.5 13.4 9.3e-05 22.2 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SCA7 PF08313.7 KII87199.1 - 2.8e-28 97.2 0.2 2.8e-28 97.2 0.1 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain Glyco_hydro_3_C PF01915.17 KII87199.1 - 0.0066 15.9 0.3 0.0086 15.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF3138 PF11336.3 KII87199.1 - 0.85 7.7 10.3 1.2 7.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PNRC PF15365.1 KII87199.1 - 1.8 8.6 10.4 1.2 9.2 5.3 2.1 1 1 1 2 2 2 0 Proline-rich nuclear receptor coactivator F-box-like PF12937.2 KII87201.1 - 9.9e-07 28.3 0.1 2.6e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like RNA_pol_Rpc4 PF05132.9 KII87202.1 - 9.5e-24 83.8 0.0 9.5e-24 83.8 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 PAT1 PF09770.4 KII87204.1 - 8e-164 546.9 37.9 9.1e-164 546.8 26.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 KII87205.1 - 8.9e-71 233.6 2.1 4.5e-24 83.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Alg14 PF08660.6 KII87205.1 - 0.057 13.4 0.2 0.71 9.8 0.1 2.0 1 1 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like KduI PF04962.7 KII87205.1 - 0.096 11.7 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 KduI/IolB family Pribosyltran PF00156.22 KII87206.1 - 4.5e-06 26.3 0.0 9e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain hDGE_amylase PF14701.1 KII87207.1 - 1.1e-155 518.6 0.0 1.5e-155 518.2 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KII87207.1 - 1.5e-114 382.5 0.0 2.1e-114 382.0 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KII87207.1 - 1.7e-80 269.9 0.0 2.4e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KII87207.1 - 5.7e-19 67.7 0.0 1.2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KII87207.1 - 0.0014 18.0 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Amidase PF01425.16 KII87208.1 - 4.6e-99 332.2 0.0 5.6e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.17 KII87209.1 - 2.9e-27 94.1 1.7 6.6e-12 44.8 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87209.1 - 6.5e-20 70.8 0.1 1.5e-07 31.2 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87209.1 - 1.6e-14 53.4 0.1 0.00054 19.7 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fis1_TPR_C PF14853.1 KII87210.1 - 1.5e-22 79.1 0.1 2.5e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KII87210.1 - 2.8e-16 58.5 0.0 4.4e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KII87210.1 - 0.00023 20.8 0.1 0.00052 19.7 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII87210.1 - 0.0091 15.5 0.3 0.017 14.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII87210.1 - 0.03 14.6 0.2 0.07 13.4 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KII87210.1 - 0.037 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KII87210.1 - 0.052 13.1 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 KII87210.1 - 0.07 13.6 0.0 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Histone PF00125.19 KII87211.1 - 4e-26 90.9 0.0 5e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII87211.1 - 7.1e-06 25.9 0.0 9.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M50B PF13398.1 KII87212.1 - 2.4e-42 144.5 16.6 3.1e-42 144.2 11.5 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF1317 PF07026.6 KII87212.1 - 0.034 14.0 0.5 0.063 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) DUF3366 PF11846.3 KII87212.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) MFS_1 PF07690.11 KII87214.1 - 1e-18 67.1 28.6 1e-18 67.1 19.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2569 PF10754.4 KII87214.1 - 7.7 6.7 14.5 0.59 10.3 5.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) F-box-like PF12937.2 KII87215.1 - 0.0001 21.9 1.8 0.00023 20.8 0.3 2.4 2 0 0 2 2 2 1 F-box-like Pol_alpha_B_N PF08418.5 KII87216.1 - 0.098 12.1 0.7 2.9 7.3 0.5 2.0 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal PDE8 PF08629.5 KII87216.1 - 1.8 8.4 13.4 46 3.9 0.0 5.3 2 2 3 5 5 5 0 PDE8 phosphodiesterase Cauli_VI PF01693.11 KII87219.1 - 1.2e-05 25.2 0.1 1.7e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin MtrA PF04208.9 KII87220.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A DnaB_2 PF07261.6 KII87220.1 - 0.3 10.7 1.7 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment adh_short_C2 PF13561.1 KII87221.1 - 1.6e-31 109.9 0.0 2e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII87221.1 - 4.8e-15 55.8 0.0 6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87221.1 - 7.8e-06 25.6 0.0 1.1e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Oxidored_nitro PF00148.14 KII87221.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.14 KII87221.1 - 0.028 13.5 0.1 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KII87221.1 - 0.029 14.3 0.4 0.046 13.7 0.3 1.4 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KII87221.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LRR_7 PF13504.1 KII87222.1 - 4.2 8.0 5.1 84 4.0 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat DEAD PF00270.24 KII87223.1 - 2.6e-44 150.7 0.0 8.3e-44 149.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII87223.1 - 3.7e-27 93.9 0.2 9.1e-27 92.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII87223.1 - 0.00058 19.7 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-Sec23_Sec24 PF04810.10 KII87224.1 - 0.024 14.2 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Arginosuc_synth PF00764.14 KII87225.1 - 6.2e-152 506.1 0.0 7.5e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KII87225.1 - 0.00053 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KII87225.1 - 0.0046 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KII87225.1 - 0.032 12.8 0.0 0.059 11.9 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase F-box PF00646.28 KII87227.1 - 7.9e-05 22.2 0.9 0.00015 21.3 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII87227.1 - 0.26 11.0 3.1 0.28 10.9 1.0 1.9 2 0 0 2 2 2 0 F-box-like zf-RING_2 PF13639.1 KII87228.1 - 7.6e-10 38.4 5.4 2.6e-08 33.5 1.4 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 KII87228.1 - 2e-07 31.0 2.2 5.6e-07 29.5 1.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KII87228.1 - 4e-06 26.3 1.7 1.2e-05 24.8 1.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII87228.1 - 9.8e-05 21.9 1.7 9.8e-05 21.9 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII87228.1 - 0.00023 21.1 2.2 0.00023 21.1 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII87228.1 - 0.00043 19.9 1.1 0.00043 19.9 0.8 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KII87228.1 - 0.0011 18.7 1.0 0.003 17.3 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KII87228.1 - 0.028 14.0 0.3 0.061 12.9 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KII87228.1 - 0.15 11.5 3.1 0.33 10.4 2.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger DUF2360 PF10152.4 KII87228.1 - 1.3 9.2 3.5 2.7 8.2 2.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-C3HC4_3 PF13920.1 KII87229.1 - 1.3e-08 34.3 4.3 2.1e-08 33.7 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII87229.1 - 1.6e-08 34.2 7.9 3.2e-08 33.2 5.5 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII87229.1 - 1.9e-08 34.1 5.9 5.6e-08 32.6 4.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII87229.1 - 1.1e-06 28.1 0.7 2.2e-06 27.2 0.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII87229.1 - 1.9e-06 27.4 4.8 3.2e-06 26.7 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII87229.1 - 2.9e-05 23.8 2.6 2.9e-05 23.8 1.8 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII87229.1 - 0.001 18.7 3.3 0.0023 17.6 2.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KII87229.1 - 0.0025 17.5 0.4 0.005 16.5 0.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein AKNA PF12443.3 KII87229.1 - 0.0058 16.6 3.0 0.012 15.5 2.1 1.6 1 0 0 1 1 1 1 AT-hook-containing transcription factor ADIP PF11559.3 KII87229.1 - 0.028 14.3 8.5 0.043 13.7 5.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec8_exocyst PF04048.9 KII87229.1 - 0.029 13.9 3.6 0.058 13.0 2.5 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF1732 PF08340.6 KII87229.1 - 0.045 13.5 4.8 0.075 12.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) AAA_13 PF13166.1 KII87229.1 - 0.085 11.3 4.6 0.12 10.8 3.2 1.1 1 0 0 1 1 1 0 AAA domain DivIVA PF05103.8 KII87229.1 - 0.088 12.8 5.5 0.15 12.1 3.8 1.3 1 0 0 1 1 1 0 DivIVA protein ATG16 PF08614.6 KII87229.1 - 0.16 11.7 8.8 0.29 10.9 6.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KII87229.1 - 0.29 9.7 8.1 0.42 9.2 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KII87229.1 - 0.94 8.3 6.9 1.5 7.7 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 KII87229.1 - 6 5.8 6.8 9.4 5.2 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.17 KII87229.1 - 7.6 6.6 11.7 0.6 10.1 1.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CDC45 PF02724.9 KII87233.1 - 0.83 7.6 7.6 1.2 7.1 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KII87233.1 - 1.6 7.9 9.9 2.7 7.1 6.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KII87233.1 - 9.9 3.9 11.3 14 3.4 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 KII87234.1 - 0.82 9.1 5.2 1.8 8.0 3.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Dicty_REP PF05086.7 KII87237.1 - 1.5 6.4 3.4 2 6.0 2.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3753 PF12575.3 KII87238.1 - 0.084 12.6 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) Fer4_3 PF12798.2 KII87238.1 - 8.1 7.2 6.6 29 5.5 0.6 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain His_Phos_2 PF00328.17 KII87239.1 - 6.9e-26 91.3 0.0 8.1e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RINGv PF12906.2 KII87240.1 - 1.1e-15 57.3 7.3 2e-15 56.5 5.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KII87240.1 - 0.26 11.1 8.2 0.45 10.3 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KII87240.1 - 2.5 7.7 8.2 4.4 6.9 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mito_carr PF00153.22 KII87241.1 - 1.5e-32 111.1 7.0 1.4e-18 66.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4514 PF14986.1 KII87241.1 - 0.07 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) DHBP_synthase PF00926.14 KII87242.1 - 4.7e-81 270.6 0.2 5.6e-81 270.4 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PS_Dcarbxylase PF02666.10 KII87243.1 - 3.2e-50 170.2 0.0 4.3e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KII87243.1 - 0.081 12.5 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like Asp PF00026.18 KII87244.1 - 8e-35 120.5 0.6 2.8e-22 79.3 3.9 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII87244.1 - 1.3e-05 25.5 2.1 0.0022 18.4 0.7 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KII87244.1 - 0.0017 18.3 1.3 0.0039 17.1 0.5 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KII87244.1 - 0.0026 17.5 1.0 0.024 14.4 0.1 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Salt_tol_Pase PF09506.5 KII87244.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) PS_Dcarbxylase PF02666.10 KII87245.1 - 0.029 13.6 4.7 0.34 10.1 3.3 2.3 1 1 0 1 1 1 0 Phosphatidylserine decarboxylase adh_short PF00106.20 KII87246.1 - 3.6e-26 92.0 3.8 5.5e-26 91.4 2.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87246.1 - 3.2e-17 63.1 0.0 3.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII87246.1 - 5.8e-07 29.7 0.7 8.5e-07 29.1 0.5 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII87246.1 - 7.8e-07 28.7 0.1 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KII87246.1 - 3.4e-06 26.8 3.0 6.1e-06 26.0 2.0 1.4 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KII87246.1 - 0.00013 21.5 0.2 0.00022 20.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII87246.1 - 0.00042 20.3 0.1 0.00072 19.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 KII87246.1 - 0.00045 19.5 0.1 0.00082 18.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 KII87246.1 - 0.013 14.6 0.1 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAE PF03283.8 KII87246.1 - 0.015 13.9 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase ApbA PF02558.11 KII87246.1 - 0.061 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_transf_28 PF03033.15 KII87246.1 - 0.068 12.9 0.6 0.25 11.0 0.3 2.0 1 1 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain RmlD_sub_bind PF04321.12 KII87246.1 - 0.085 11.7 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain RTC4 PF14474.1 KII87247.1 - 2.2e-27 95.4 0.0 4.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DNA_pol_phi PF04931.8 KII87247.1 - 8.5 4.0 11.3 13 3.4 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Smac_DIABLO PF09057.5 KII87250.1 - 0.024 13.7 2.9 0.036 13.1 2.0 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Med11 PF10280.4 KII87250.1 - 0.071 13.1 2.3 0.12 12.4 1.6 1.3 1 0 0 1 1 1 0 Mediator complex protein FliJ PF02050.11 KII87250.1 - 0.11 12.5 6.1 0.16 11.9 4.2 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Nnf1 PF03980.9 KII87251.1 - 1e-08 35.1 0.4 1.5e-08 34.5 0.3 1.3 1 0 0 1 1 1 1 Nnf1 CASP_C PF08172.7 KII87251.1 - 0.002 17.1 0.5 0.0027 16.7 0.3 1.1 1 0 0 1 1 1 1 CASP C terminal CCDC155 PF14662.1 KII87251.1 - 0.11 12.1 0.8 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 zf-LSD1 PF06943.7 KII87253.1 - 0.71 9.5 3.4 1.6 8.4 1.4 2.2 2 0 0 2 2 2 0 LSD1 zinc finger Asp PF00026.18 KII87254.1 - 9.4e-66 222.2 7.7 1.3e-65 221.7 5.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII87254.1 - 4.8e-07 29.8 6.1 7.1e-07 29.3 2.6 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII87254.1 - 0.0017 18.8 0.8 0.05 14.0 0.0 3.2 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 KII87254.1 - 0.042 13.4 0.1 0.42 10.1 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Methyltransf_16 PF10294.4 KII87255.1 - 4e-28 98.0 0.0 5.6e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 KII87255.1 - 0.0033 17.8 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KII87255.1 - 0.03 13.6 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 KII87255.1 - 0.061 13.8 0.0 0.51 10.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 KII87255.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 KII87255.1 - 0.16 11.3 0.1 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Rhomboid PF01694.17 KII87256.1 - 1.5e-16 60.6 10.8 3.4e-15 56.3 7.5 2.4 1 1 0 1 1 1 1 Rhomboid family Histone PF00125.19 KII87257.1 - 3.9e-30 103.7 0.8 6.6e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII87257.1 - 1.3e-05 25.3 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KII87257.1 - 0.00078 19.4 1.6 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KII87257.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KII87257.1 - 0.14 11.4 1.3 0.16 11.1 0.9 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KII87258.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII87258.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KII87258.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KII87258.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KII87258.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KII87258.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit adh_short PF00106.20 KII87259.1 - 1e-13 51.5 0.9 1.3e-13 51.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KII87259.1 - 1.6e-08 34.2 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KII87259.1 - 3.8e-06 26.6 0.2 5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII87259.1 - 9.5e-05 22.2 0.1 0.00012 21.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CRCB PF02537.10 KII87259.1 - 0.1 12.4 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 CrcB-like protein Glyco_tran_WecB PF03808.8 KII87259.1 - 0.1 11.9 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MFS_1 PF07690.11 KII87260.1 - 6.6e-16 57.9 40.2 6.6e-16 57.9 27.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KII87260.1 - 0.0018 16.7 14.0 0.0018 16.7 9.7 2.3 1 1 2 3 3 3 2 MFS/sugar transport protein RhoGAP PF00620.22 KII87261.1 - 2.9e-46 156.8 0.0 6.5e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KII87261.1 - 3.1e-16 59.3 1.3 5.5e-15 55.3 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Glucodextran_B PF09136.5 KII87261.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Glucodextranase, domain B TMPIT PF07851.8 KII87261.1 - 0.12 11.4 4.1 0.19 10.7 2.4 1.6 2 0 0 2 2 2 0 TMPIT-like protein Baculo_PEP_C PF04513.7 KII87261.1 - 0.15 11.9 0.9 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 KII87261.1 - 0.42 10.7 4.7 2.6 8.2 1.8 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PA26 PF04636.8 KII87261.1 - 0.54 8.8 3.4 0.83 8.2 2.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nucleopor_Nup85 PF07575.8 KII87265.1 - 7.8e-57 192.7 0.0 2.1e-37 128.6 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin TPR_11 PF13414.1 KII87266.1 - 8.5e-12 44.5 0.6 2.9e-07 30.0 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KII87266.1 - 3.2e-07 29.7 0.7 0.011 15.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII87266.1 - 5.2e-06 25.8 0.9 0.12 12.0 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII87266.1 - 0.00011 22.1 0.2 0.086 12.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII87266.1 - 0.0086 16.6 2.0 0.6 10.8 0.0 3.1 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII87266.1 - 0.0097 16.5 2.0 1.2 9.9 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII87266.1 - 0.022 14.5 0.1 0.51 10.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII87266.1 - 0.025 14.9 0.1 0.94 9.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 KII87266.1 - 0.061 13.1 0.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 KII87266.1 - 0.068 13.0 0.2 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 KII87266.1 - 0.28 11.4 1.8 4.6 7.7 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2183 PF09949.4 KII87267.1 - 1.3e-24 86.0 0.0 2.4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 KII87267.1 - 0.051 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) PTS_2-RNA PF01885.11 KII87268.1 - 2.9e-62 209.2 0.4 3.3e-62 209.1 0.3 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KII87268.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 La domain Methyltransf_16 PF10294.4 KII87269.1 - 9e-22 77.3 0.0 1.6e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KII87269.1 - 6.8e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII87269.1 - 1.6e-05 25.4 0.0 3.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KII87269.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KII87269.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KII87269.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 KII87269.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KII87269.1 - 0.054 13.5 0.4 0.15 12.0 0.3 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KII87269.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 KII87270.1 - 0.0075 15.9 0.5 0.035 13.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like TauD PF02668.11 KII87271.1 - 1.5e-17 64.1 0.0 4.7e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KII87271.1 - 0.061 12.2 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.11 KII87272.1 - 8.1e-16 57.6 37.7 8.1e-16 57.6 26.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Histone PF00125.19 KII87273.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII87273.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KII87273.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KII87273.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KII87273.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KII87273.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KII87274.1 - 3.9e-30 103.7 0.8 6.6e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII87274.1 - 1.3e-05 25.3 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KII87274.1 - 0.00078 19.4 1.6 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KII87274.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KII87274.1 - 0.14 11.4 1.3 0.16 11.1 0.9 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T SIR2 PF02146.12 KII87275.1 - 2e-59 200.2 0.0 3.3e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KII87275.1 - 0.0049 16.4 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) adh_short_C2 PF13561.1 KII87276.1 - 5.8e-26 91.7 0.0 7.1e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII87276.1 - 1.4e-09 38.0 0.1 2e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 KII87276.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KII87276.1 - 0.032 14.2 0.2 0.059 13.3 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 KII87276.1 - 0.047 13.5 0.1 0.096 12.5 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.21 KII87276.1 - 0.1 12.1 0.2 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KII87276.1 - 0.14 11.9 0.6 0.29 10.9 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pox_Ag35 PF03286.9 KII87277.1 - 0.00012 21.7 4.5 0.00012 21.7 3.1 1.4 2 0 0 2 2 2 1 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 KII87277.1 - 0.14 12.0 13.9 0.019 14.9 7.2 1.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.9 KII87277.1 - 0.43 10.7 25.5 0.74 9.9 17.7 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family BTV_NS2 PF04514.7 KII87277.1 - 0.5 9.2 7.9 0.58 8.9 5.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FYDLN_acid PF09538.5 KII87277.1 - 0.6 10.7 13.3 1 9.9 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TLP-20 PF06088.6 KII87277.1 - 0.67 9.6 4.7 0.95 9.1 3.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FLO_LFY PF01698.11 KII87277.1 - 0.9 8.3 5.6 0.99 8.1 3.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Sporozoite_P67 PF05642.6 KII87277.1 - 1.7 6.3 6.7 2.1 6.1 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 KII87277.1 - 2.2 7.5 13.1 2.6 7.3 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 KII87277.1 - 3.7 7.0 13.7 4.6 6.6 9.5 1.2 1 0 0 1 1 1 0 PPP4R2 S-antigen PF05756.6 KII87277.1 - 6.2 6.8 10.4 9.7 6.2 7.2 1.4 1 0 0 1 1 1 0 S-antigen protein Spore_coat_CotO PF14153.1 KII87277.1 - 7.5 5.9 9.5 8.8 5.7 6.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 KII87277.1 - 8 4.2 17.8 8.9 4.0 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family ECR1_N PF14382.1 KII87278.1 - 1e-15 56.7 0.1 2e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KII87278.1 - 0.00061 19.6 0.1 0.025 14.5 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 TFIIIC_delta PF12657.2 KII87279.1 - 1.8e-26 92.9 0.7 6.3e-26 91.1 0.5 2.0 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KII87279.1 - 1.1e-21 76.6 1.4 2.4e-21 75.4 1.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.27 KII87279.1 - 0.01 15.6 6.2 1.2 9.0 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2024 PF09630.5 KII87281.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-MYND PF01753.13 KII87282.1 - 5.3e-07 29.3 15.5 9.8e-07 28.5 10.8 1.4 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 KII87282.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.1 KII87282.1 - 3.3 7.6 10.2 6.6 6.6 6.5 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RRM_1 PF00076.17 KII87283.1 - 1.2e-15 56.9 0.0 1.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87283.1 - 5e-12 45.6 0.0 1.1e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87283.1 - 8.2e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII87283.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Chromo PF00385.19 KII87284.1 - 2.3e-11 43.1 0.0 6.8e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KII87284.1 - 3.4e-06 26.8 0.0 3.7e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain SOBP PF15279.1 KII87284.1 - 0.61 10.4 4.3 0.79 10.0 3.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3246 PF11596.3 KII87284.1 - 4.9 6.3 8.4 0.14 11.4 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) ASFV_J13L PF05568.6 KII87285.1 - 0.0082 15.6 7.3 0.0082 15.6 5.1 1.8 1 1 0 1 1 1 1 African swine fever virus J13L protein DUF2365 PF10157.4 KII87285.1 - 0.0082 16.0 1.8 0.14 11.9 0.6 2.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2365) Isochorismatase PF00857.15 KII87286.1 - 3.2e-22 79.2 0.0 1.2e-21 77.4 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Smr PF01713.16 KII87287.1 - 6.9e-11 42.1 0.0 2.5e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KII87287.1 - 0.02 14.9 3.0 0.042 13.8 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DUF2015 PF09435.5 KII87288.1 - 8.3e-35 119.3 0.0 9.2e-35 119.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF1680 PF07944.7 KII87289.1 - 1.6e-23 82.7 0.0 2.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) adh_short PF00106.20 KII87291.1 - 1.2e-18 67.6 0.9 1.6e-18 67.1 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KII87291.1 - 1.3e-08 34.5 0.1 1.9e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KII87291.1 - 4.7e-07 29.6 0.2 8.6e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII87291.1 - 5.3e-07 29.6 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 KII87291.1 - 0.0022 17.4 0.4 0.14 11.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family DUF2969 PF11184.3 KII87295.1 - 0.054 13.5 0.0 2.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2969) WD40 PF00400.27 KII87296.1 - 1e-151 488.0 57.9 3.2e-13 49.0 0.4 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat PD40 PF07676.7 KII87296.1 - 2.5e-18 65.3 22.1 2.7 7.7 0.0 11.9 12 0 0 12 12 12 8 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KII87296.1 - 3.6e-18 65.0 0.2 0.049 11.8 0.0 7.7 1 1 5 8 8 8 8 Protein of unknown function (DUF3312) UN_NPL4 PF11543.3 KII87296.1 - 6e-05 23.2 2.5 22 5.3 0.0 7.8 9 3 1 11 11 11 0 Nuclear pore localisation protein NPL4 DUF1258 PF06869.7 KII87296.1 - 0.00081 18.5 5.3 0.35 9.9 0.0 5.3 1 1 4 7 7 7 1 Protein of unknown function (DUF1258) FLYWCH PF04500.11 KII87296.1 - 0.0019 18.0 0.0 0.37 10.7 0.0 3.9 4 0 0 4 4 3 1 FLYWCH zinc finger domain DUF2244 PF10003.4 KII87296.1 - 0.022 14.1 0.0 23 4.3 0.0 4.3 4 2 3 7 7 7 0 Integral membrane protein (DUF2244) DdrB PF12747.2 KII87296.1 - 0.054 13.2 0.9 20 4.8 0.0 4.7 6 0 0 6 6 6 0 DdrB-like protein DUF1913 PF08931.5 KII87296.1 - 0.069 12.9 3.7 21 4.9 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF1913) CbiG_N PF11760.3 KII87296.1 - 0.79 9.4 7.5 93 2.8 0.0 6.0 9 0 0 9 9 9 0 Cobalamin synthesis G N-terminal Proteasome_A_N PF10584.4 KII87296.1 - 4.5 6.6 29.3 25 4.3 0.0 9.6 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature DUF463 PF04317.7 KII87297.1 - 0.0051 15.4 1.0 0.11 11.0 0.1 2.0 1 1 1 2 2 2 2 YcjX-like family, DUF463 DUF1368 PF07112.6 KII87297.1 - 0.068 11.7 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) C8 PF08742.6 KII87297.1 - 0.091 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 C8 domain DUF533 PF04391.7 KII87297.1 - 0.19 11.0 1.4 0.33 10.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF4413 PF14372.1 KII87298.1 - 7e-05 22.7 0.2 8.3e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) adh_short PF00106.20 KII87299.1 - 5.4e-08 32.9 0.4 8.5e-08 32.2 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase DUF2917 PF11142.3 KII87303.1 - 0.069 12.3 0.2 2.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Cornifin PF02389.10 KII87304.1 - 4.3e-09 36.4 22.3 8.2e-09 35.5 15.5 1.4 1 1 0 1 1 1 1 Cornifin (SPRR) family AIRC PF00731.15 KII87305.1 - 1.4 8.2 5.2 12 5.1 0.2 2.3 1 1 1 2 2 2 0 AIR carboxylase DDE_1 PF03184.14 KII87308.1 - 1.4e-36 125.6 0.0 1.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KII87308.1 - 5.9e-06 26.0 0.0 2.7e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KII87308.1 - 0.00095 18.9 0.2 0.0059 16.4 0.0 2.4 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain NB-ARC PF00931.17 KII87311.1 - 9.1e-07 28.0 0.0 1.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KII87311.1 - 2.3e-06 27.3 0.0 9.9e-06 25.3 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KII87311.1 - 0.00092 19.2 0.0 0.0061 16.5 0.0 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KII87311.1 - 0.0043 17.3 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KII87311.1 - 0.0063 16.7 0.3 0.063 13.4 0.1 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KII87311.1 - 0.0083 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase APS_kinase PF01583.15 KII87311.1 - 0.012 15.2 0.2 0.027 14.1 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase NTPase_1 PF03266.10 KII87311.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 KII87311.1 - 0.023 15.5 0.0 0.052 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KII87311.1 - 0.023 14.8 0.0 0.11 12.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII87311.1 - 0.033 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 KII87311.1 - 0.034 13.9 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KII87311.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KII87311.1 - 0.06 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 KII87311.1 - 0.091 12.6 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PGM_PMM_I PF02878.11 KII87312.1 - 1.5e-37 128.1 0.2 2.5e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KII87312.1 - 1.5e-25 89.4 0.0 3e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KII87312.1 - 2.4e-13 50.3 0.0 8.4e-13 48.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KII87312.1 - 2.7e-07 30.4 0.0 6.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MFS_1 PF07690.11 KII87313.1 - 4.4e-19 68.3 37.9 6.7e-19 67.8 26.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KII87313.1 - 0.084 12.6 0.2 0.084 12.6 0.1 3.0 2 1 0 2 2 2 0 MFS_1 like family Chordopox_A13L PF05961.6 KII87313.1 - 0.15 12.0 1.9 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Hydantoinase_B PF02538.9 KII87314.1 - 2.5e-165 550.6 0.1 4e-165 550.0 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KII87314.1 - 2.9e-91 305.5 0.4 2.9e-91 305.5 0.3 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KII87314.1 - 4.1e-60 202.2 1.8 5e-59 198.7 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF499 PF04465.7 KII87314.1 - 0.62 7.5 0.0 0.85 7.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) ERG4_ERG24 PF01222.12 KII87315.1 - 3.2e-128 427.9 24.4 3.7e-128 427.7 16.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KII87315.1 - 3.6e-05 23.1 2.8 7.6e-05 22.1 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KII87315.1 - 0.024 14.8 0.9 0.072 13.3 0.1 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Carb_kinase PF01256.12 KII87316.1 - 6.1e-50 169.7 0.0 1.1e-48 165.6 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KII87316.1 - 0.066 12.3 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase Methyltransf_2 PF00891.13 KII87317.1 - 2.7e-31 108.6 0.0 8.1e-31 107.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KII87317.1 - 8.5e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TFIID-18kDa PF02269.11 KII87317.1 - 0.095 12.5 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit MTS PF05175.9 KII87317.1 - 0.097 12.0 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KII87317.1 - 0.11 13.0 0.1 0.59 10.7 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Zw10 PF06248.8 KII87318.1 - 1.7e-22 79.3 0.0 2.6e-13 49.0 0.0 3.4 2 2 1 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KII87318.1 - 6.5e-08 32.0 0.0 1.6e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Baculo_PEP_C PF04513.7 KII87318.1 - 0.52 10.1 3.1 1.4 8.7 0.6 2.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 KII87319.1 - 2.5e-09 36.6 2.8 2.9 7.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat DnaJ PF00226.26 KII87321.1 - 1.3e-24 85.7 0.2 2.2e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KII87321.1 - 4.5e-10 39.7 0.0 9.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_12 PF13424.1 KII87321.1 - 0.13 12.2 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MSP1_C PF07462.6 KII87321.1 - 1.1 7.5 2.9 1.5 7.1 2.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus F-box PF00646.28 KII87322.1 - 7.4e-05 22.2 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 KII87322.1 - 9.8e-05 21.7 0.3 0.00022 20.6 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII87322.1 - 0.0001 21.9 0.7 0.00026 20.6 0.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box-like PF12937.2 KII87322.1 - 0.00025 20.7 0.1 0.00091 18.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like MIT PF04212.13 KII87322.1 - 0.00058 19.6 0.4 0.0011 18.8 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KII87322.1 - 0.0032 17.8 0.7 0.28 11.7 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII87322.1 - 0.0053 17.2 1.8 0.021 15.4 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII87322.1 - 0.0089 15.9 0.6 0.019 14.8 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII87322.1 - 0.0093 15.5 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.1 KII87322.1 - 0.013 15.2 1.0 0.05 13.4 0.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TM231 PF10149.4 KII87322.1 - 0.046 12.7 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 BCS1_N PF08740.6 KII87323.1 - 1.9e-27 96.1 0.3 3e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KII87323.1 - 3.4e-15 56.4 0.0 2.4e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KII87323.1 - 0.003 16.5 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KII87323.1 - 0.005 16.2 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII87323.1 - 0.006 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 KII87323.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 KII87323.1 - 0.024 15.4 0.0 0.071 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII87323.1 - 0.027 14.1 0.2 0.073 12.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 KII87323.1 - 0.027 14.6 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KII87323.1 - 0.031 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KII87323.1 - 0.033 13.2 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 KII87323.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_21 PF13304.1 KII87323.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KII87323.1 - 0.054 13.9 0.1 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein TIP49 PF06068.8 KII87323.1 - 0.061 12.0 0.0 0.093 11.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 KII87323.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 KII87323.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KII87323.1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KII87323.1 - 0.09 12.3 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KII87323.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 KII87323.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KII87323.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Thymidylat_synt PF00303.14 KII87324.1 - 4.2e-106 353.8 0.0 4.8e-106 353.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase ubiquitin PF00240.18 KII87325.1 - 6.5e-35 118.3 0.7 1.4e-34 117.2 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KII87325.1 - 2.3e-27 94.5 2.4 5e-27 93.4 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KII87325.1 - 7.9e-20 70.3 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KII87325.1 - 9.5e-06 25.7 0.5 5e-05 23.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KII87325.1 - 0.00022 20.9 0.2 0.00035 20.3 0.0 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KII87325.1 - 0.00029 20.6 0.6 0.00064 19.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KII87325.1 - 0.0058 16.7 0.9 0.0077 16.3 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2207 PF09972.4 KII87325.1 - 0.013 14.0 0.8 0.015 13.8 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stig1 PF04885.8 KII87325.1 - 0.027 14.6 0.2 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF971 PF06155.7 KII87325.1 - 0.035 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) IBR PF01485.16 KII87325.1 - 0.044 13.6 0.9 0.07 13.0 0.6 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 KII87325.1 - 0.071 11.4 3.0 0.61 8.3 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 KII87325.1 - 0.11 12.5 1.7 0.12 12.4 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Rep_fac_C PF08542.6 KII87326.1 - 1e-20 73.5 0.0 2.9e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KII87326.1 - 9.9e-18 64.6 0.0 1.9e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KII87326.1 - 7.5e-17 61.4 0.0 9.4e-15 54.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KII87326.1 - 2.6e-09 36.3 0.0 1.5e-07 30.5 0.0 2.4 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KII87326.1 - 1.4e-07 31.4 0.2 6.4e-07 29.3 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 KII87326.1 - 2.7e-07 30.7 1.2 0.00045 20.3 0.5 3.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII87326.1 - 6.2e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KII87326.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 KII87326.1 - 2.9e-05 23.7 0.3 0.00028 20.5 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KII87326.1 - 3.4e-05 23.5 0.1 9.4e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII87326.1 - 4.1e-05 22.7 0.0 9.3e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KII87326.1 - 5.9e-05 23.1 0.0 0.0004 20.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KII87326.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 KII87326.1 - 0.00038 20.0 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII87326.1 - 0.00068 19.3 0.1 0.007 16.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 KII87326.1 - 0.0012 18.4 0.7 0.014 14.8 0.1 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_24 PF13479.1 KII87326.1 - 0.0018 17.9 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KII87326.1 - 0.003 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 KII87326.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KII87326.1 - 0.011 15.4 0.1 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KII87326.1 - 0.012 14.9 0.3 0.058 12.7 0.1 2.1 2 1 0 2 2 1 0 AAA domain ResIII PF04851.10 KII87326.1 - 0.013 15.3 0.1 0.065 13.0 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 KII87326.1 - 0.017 15.9 0.0 0.037 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KII87326.1 - 0.028 13.3 0.0 0.1 11.4 0.0 1.8 1 1 0 2 2 2 0 Type II/IV secretion system protein SNF2_N PF00176.18 KII87326.1 - 0.03 13.1 0.1 0.17 10.6 0.0 2.2 2 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_10 PF12846.2 KII87326.1 - 0.034 13.6 0.1 1.9 7.8 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KII87326.1 - 0.035 14.0 0.1 0.073 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.10 KII87326.1 - 0.038 13.6 0.2 2.8 7.5 0.0 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PIF1 PF05970.9 KII87326.1 - 0.042 12.8 0.1 0.89 8.4 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase Mg_chelatase PF01078.16 KII87326.1 - 0.042 13.0 0.0 0.33 10.1 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Methyltransf_31 PF13847.1 KII87326.1 - 0.06 12.9 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF2075 PF09848.4 KII87326.1 - 0.086 11.7 0.0 0.3 10.0 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_6 PF13174.1 KII87326.1 - 0.11 12.9 1.5 2.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.1 KII87326.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain Fapy_DNA_glyco PF01149.19 KII87327.1 - 0.11 12.8 0.0 0.7 10.2 0.0 2.0 1 1 1 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain F-box-like PF12937.2 KII87327.1 - 0.13 12.0 0.3 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 F-box-like DUF1749 PF08538.5 KII87327.1 - 0.13 11.1 0.0 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Secretin_N_2 PF07655.8 KII87328.1 - 1.1 9.6 5.9 19 5.7 4.1 2.3 1 1 0 1 1 1 0 Secretin N-terminal domain RED_N PF07808.8 KII87329.1 - 2.2e-15 56.5 10.4 2.2e-15 56.5 7.2 1.7 2 0 0 2 2 2 1 RED-like protein N-terminal region MMgT PF10270.4 KII87330.1 - 3.6e-13 49.8 0.0 6.5e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Membrane magnesium transporter F-box-like PF12937.2 KII87333.1 - 9.6e-06 25.2 2.4 9.8e-06 25.2 0.4 2.1 2 0 0 2 2 2 1 F-box-like SIR2 PF02146.12 KII87334.1 - 7.9e-32 110.4 0.0 1.2e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family WD40 PF00400.27 KII87335.1 - 1.5e-40 135.6 16.7 1.1e-09 37.7 0.0 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KII87335.1 - 0.022 13.5 0.0 3 6.4 0.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like DUF4500 PF14937.1 KII87336.1 - 0.0043 16.8 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) U1snRNP70_N PF12220.3 KII87336.1 - 0.052 13.8 1.4 0.063 13.6 1.0 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CCSMST1 PF15013.1 KII87336.1 - 0.066 13.1 0.5 0.61 10.0 0.0 2.0 1 1 1 2 2 2 0 CCSMST1 family CTD_bind PF04818.8 KII87337.1 - 0.0001 22.4 0.0 0.001 19.2 0.0 2.7 2 1 1 3 3 3 1 RNA polymerase II-binding domain. LepA_C PF06421.7 KII87337.1 - 0.1 12.4 0.3 0.29 11.0 0.0 1.9 3 0 0 3 3 3 0 GTP-binding protein LepA C-terminus PAP2 PF01569.16 KII87338.1 - 5.6e-21 74.5 2.2 5.6e-21 74.5 1.5 2.1 1 1 1 2 2 2 1 PAP2 superfamily UbiA PF01040.13 KII87339.1 - 5.4e-20 71.6 13.4 7.4e-20 71.2 9.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SNF2_N PF00176.18 KII87340.1 - 9.3e-21 73.8 0.0 5.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KII87340.1 - 5.5e-17 61.8 0.0 1.7e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Cript PF10235.4 KII87341.1 - 1.9e-22 79.4 6.0 1.9e-22 79.4 4.2 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.1 KII87341.1 - 0.038 13.4 14.9 4 7.0 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Gin PF10764.4 KII87341.1 - 0.071 12.8 7.6 0.89 9.3 0.0 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin stn_TNFRSF12A PF12191.3 KII87341.1 - 0.15 12.0 2.0 0.24 11.4 1.4 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Sgf11 PF08209.6 KII87341.1 - 0.15 11.3 6.2 5.7 6.3 0.2 3.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) C1_1 PF00130.17 KII87341.1 - 0.17 11.6 12.4 3.8 7.3 3.4 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2039 PF10217.4 KII87341.1 - 0.35 10.9 13.4 0.13 12.2 5.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.6 KII87341.1 - 0.35 10.7 6.8 0.4 10.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 KII87341.1 - 0.84 9.4 11.0 3.7 7.4 4.4 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.1 KII87341.1 - 0.96 8.7 10.1 5.2 6.4 2.7 3.1 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 KII87341.1 - 1.5 8.5 6.2 1.3 8.7 2.2 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 KII87341.1 - 1.7 8.4 15.4 4.6 7.0 0.1 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DUF4428 PF14471.1 KII87341.1 - 6.1 6.6 11.9 1 9.1 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.1 KII87341.1 - 7.2 6.3 14.7 96 2.7 5.0 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_16 PF10294.4 KII87342.1 - 1.7e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII87342.1 - 7.2e-09 36.2 0.1 1.5e-08 35.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII87342.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KII87342.1 - 0.02 15.3 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KII87342.1 - 0.039 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 KII87342.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF4451 PF14616.1 KII87343.1 - 0.011 15.5 8.4 0.7 9.6 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4451) SnAC PF14619.1 KII87343.1 - 0.024 14.7 0.3 0.11 12.6 0.2 2.1 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex BIR PF00653.16 KII87343.1 - 9.6 6.7 10.3 16 6.0 0.2 3.4 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Cu-oxidase PF00394.17 KII87344.1 - 3.5e-49 166.7 0.2 1.1e-44 152.1 0.0 2.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KII87344.1 - 6.9e-39 132.5 1.8 4.4e-36 123.4 0.0 3.6 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KII87344.1 - 8.9e-36 122.2 0.1 4e-34 116.8 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KII87346.1 - 2.9e-48 163.7 0.0 1.4e-44 151.7 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KII87346.1 - 1.5e-40 137.9 1.4 2.9e-36 124.0 0.0 3.9 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KII87346.1 - 2.5e-36 123.9 0.2 1.6e-34 118.1 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Zn_clus PF00172.13 KII87350.1 - 2.8e-24 84.7 78.1 3e-07 30.2 7.3 5.1 4 1 1 5 5 5 4 Fungal Zn(2)-Cys(6) binuclear cluster domain DWNN PF08783.6 KII87351.1 - 1.7e-29 101.5 1.5 1.9e-29 101.4 0.2 1.8 2 0 0 2 2 1 1 DWNN domain zf-CCHC_2 PF13696.1 KII87351.1 - 2.6e-07 30.0 2.9 5.5e-07 28.9 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KII87351.1 - 2.4e-05 24.0 2.0 2.4e-05 24.0 1.4 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 KII87351.1 - 0.00015 21.4 0.8 0.0004 20.0 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 KII87351.1 - 0.00016 21.6 8.1 0.00016 21.6 5.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KII87351.1 - 0.0025 17.7 0.5 0.0075 16.2 0.0 2.1 2 0 0 2 2 1 1 U-box domain zf-RING_2 PF13639.1 KII87351.1 - 0.0031 17.3 7.1 0.0031 17.3 4.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII87351.1 - 0.59 9.8 12.4 0.044 13.4 3.2 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII87351.1 - 0.94 9.1 8.3 2.2 7.9 5.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 KII87351.1 - 1.9 8.0 5.8 0.15 11.5 0.3 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-H2C2_2 PF13465.1 KII87351.1 - 2.2 8.7 5.9 4.5 7.7 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_4 PF15227.1 KII87351.1 - 2.3 8.1 9.0 6.9 6.6 6.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KII87351.1 - 4.9 6.9 12.2 0.58 9.9 4.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Troponin-I_N PF11636.3 KII87351.1 - 7.7 6.3 7.7 0.51 10.0 1.4 2.0 2 0 0 2 2 2 0 Troponin I residues 1-32 Vps5 PF09325.5 KII87352.1 - 2.4e-67 226.6 3.5 3.4e-67 226.1 2.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KII87352.1 - 1.6e-27 95.5 0.1 1.3e-26 92.5 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR PF03114.13 KII87352.1 - 9.3e-07 28.5 1.3 1.3e-06 28.0 0.9 1.1 1 0 0 1 1 1 1 BAR domain FAM92 PF06730.6 KII87352.1 - 0.00019 20.8 2.6 0.00037 19.9 1.8 1.4 1 0 0 1 1 1 1 FAM92 protein Arfaptin PF06456.8 KII87352.1 - 0.0013 18.0 1.2 0.016 14.5 1.0 2.0 1 1 0 1 1 1 1 Arfaptin-like domain BAR_3_WASP_bdg PF10456.4 KII87352.1 - 0.0043 16.3 1.2 0.17 11.0 0.8 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PMT PF02366.13 KII87353.1 - 2.9e-76 256.0 18.1 2.9e-76 256.0 12.6 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KII87353.1 - 5.7e-16 58.6 0.9 9.4e-16 57.9 0.5 1.4 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KII87353.1 - 1.8e-06 27.9 12.1 1.8e-06 27.9 8.4 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RDD PF06271.7 KII87353.1 - 8.7 6.2 20.6 0.41 10.5 0.0 4.7 4 1 0 4 4 4 0 RDD family PX PF00787.19 KII87354.1 - 9.6e-16 57.5 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 PX domain Glyoxalase PF00903.20 KII87355.1 - 4.5e-05 23.4 0.1 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KII87355.1 - 0.0012 19.4 0.0 0.0019 18.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyco_hydro_3 PF00933.16 KII87356.1 - 6.2e-82 274.9 0.1 1e-81 274.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII87356.1 - 1.5e-57 194.7 0.1 6.4e-57 192.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII87356.1 - 5.3e-22 77.5 0.8 8.4e-22 76.8 0.2 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain ADH_N PF08240.7 KII87357.1 - 2.2e-25 88.5 0.5 2.2e-25 88.5 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII87357.1 - 1e-12 47.7 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII87357.1 - 0.059 14.2 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.20 KII87358.1 - 5.2e-57 192.9 0.0 3.8e-39 134.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII87358.1 - 6.8e-24 84.3 0.1 1.1e-18 67.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KII87358.1 - 0.00031 19.6 0.0 0.00066 18.6 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.1 KII87358.1 - 0.00035 19.6 1.4 0.0019 17.2 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KII87358.1 - 0.0022 17.1 0.2 0.0054 15.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Orbi_NS1 PF01718.11 KII87358.1 - 0.02 12.9 0.2 0.031 12.3 0.1 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein APH PF01636.18 KII87358.1 - 0.027 14.1 0.4 0.3 10.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 KII87358.1 - 0.048 14.1 0.5 0.13 12.8 0.4 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.17 KII87358.1 - 0.079 12.3 0.1 0.079 12.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 KII87359.1 - 1.7e-57 189.3 5.2 9.7e-11 41.1 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KII87359.1 - 7.8e-13 47.4 1.1 1.6e-12 46.4 0.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 KII87359.1 - 0.0005 19.2 0.0 2.9 6.8 0.0 3.2 2 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KII87359.1 - 0.11 10.5 3.7 0.76 7.8 0.1 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Ank_2 PF12796.2 KII87360.1 - 2e-12 47.2 0.1 8.2e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII87360.1 - 5.9e-12 44.7 4.1 6.1e-05 22.6 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KII87360.1 - 3.8e-11 42.8 0.3 0.00017 21.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KII87360.1 - 1.5e-09 38.0 0.5 6.4e-06 26.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII87360.1 - 7.2e-09 35.0 1.1 0.02 15.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 KII87360.1 - 0.00023 20.7 0.2 0.0046 16.5 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain DUF3562 PF12085.3 KII87360.1 - 0.061 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) PKD_channel PF08016.7 KII87361.1 - 0.0056 15.1 17.0 0.016 13.6 0.5 2.5 2 0 0 2 2 2 2 Polycystin cation channel EHN PF06441.7 KII87362.1 - 2.7e-29 101.3 0.0 1.3e-28 99.1 0.0 2.1 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII87362.1 - 6.1e-12 45.9 0.5 1e-11 45.2 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87362.1 - 2e-07 30.7 0.0 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII87362.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family EHN PF06441.7 KII87364.1 - 1.2e-34 118.6 0.1 2.2e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII87364.1 - 4.4e-11 43.1 0.7 9.4e-11 42.0 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87364.1 - 1.2e-06 28.2 0.2 4.2e-05 23.2 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold TFIIS_M PF07500.9 KII87365.1 - 5.3e-17 61.9 0.1 1.2e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KII87365.1 - 8.8e-07 29.4 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KII87366.1 - 5.1e-09 35.6 3.7 8.8e-09 34.9 2.5 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KII87366.1 - 0.014 15.1 2.4 0.023 14.4 1.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 KII87366.1 - 0.076 13.0 2.2 0.12 12.3 1.4 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 KII87366.1 - 0.16 11.7 5.6 0.26 11.0 3.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ASFV_J13L PF05568.6 KII87366.1 - 0.95 8.9 4.4 1.4 8.4 3.0 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein CMV_1a PF12467.3 KII87366.1 - 1.7 8.9 6.4 2.2 8.6 4.4 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family MAP2_projctn PF08377.5 KII87367.1 - 0.12 9.9 0.1 0.12 9.8 0.1 1.0 1 0 0 1 1 1 0 MAP2/Tau projection domain Pkinase PF00069.20 KII87368.1 - 3.8e-68 229.4 0.0 5.6e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87368.1 - 3.5e-53 180.3 0.0 5.2e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KII87368.1 - 7.8e-08 31.9 5.1 1.3e-07 31.2 3.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 KII87368.1 - 0.00028 20.8 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Kinase-like PF14531.1 KII87368.1 - 0.0005 19.1 0.0 0.0046 15.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KII87368.1 - 0.016 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 KII87368.1 - 0.044 13.1 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Prok-RING_1 PF14446.1 KII87368.1 - 0.14 11.9 3.6 0.29 10.9 2.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Seadorna_VP7 PF07387.6 KII87368.1 - 0.26 10.0 0.1 0.41 9.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KII87368.1 - 0.43 9.6 0.0 0.77 8.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 KII87368.1 - 0.95 9.2 5.4 1.9 8.2 3.8 1.4 1 0 0 1 1 1 0 PHD-finger EHN PF06441.7 KII87369.1 - 1.2e-32 112.1 0.1 2.7e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII87369.1 - 4.9e-11 42.9 1.7 9.6e-11 41.9 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87369.1 - 9e-10 38.4 0.2 1e-08 35.0 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_18 PF00704.23 KII87370.1 - 2.2e-12 47.1 1.7 2.8e-12 46.7 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF952 PF06108.7 KII87371.1 - 1.3e-22 79.4 0.0 1.6e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF3836 PF12930.2 KII87373.1 - 0.036 13.5 1.7 0.047 13.1 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Tropomyosin_1 PF12718.2 KII87374.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin like WXG100 PF06013.7 KII87374.1 - 0.029 14.3 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ApoLp-III PF07464.6 KII87374.1 - 0.04 13.9 0.3 0.075 13.0 0.2 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Rop-like PF05082.8 KII87374.1 - 0.063 12.7 0.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Rop-like Methyltransf_23 PF13489.1 KII87375.1 - 1.2e-26 93.3 0.0 1.6e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII87375.1 - 3e-21 75.6 0.0 4.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII87375.1 - 1.7e-18 66.6 0.0 2.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII87375.1 - 1.9e-17 63.5 0.0 3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII87375.1 - 1.6e-16 60.8 0.0 2.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII87375.1 - 3e-11 43.5 0.1 7.1e-11 42.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII87375.1 - 3.7e-09 36.6 0.1 1.1e-08 35.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KII87375.1 - 4.7e-08 32.4 0.0 6.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KII87375.1 - 6.6e-07 28.8 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KII87375.1 - 8.8e-07 27.9 0.0 1.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 KII87375.1 - 9.9e-06 24.8 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KII87375.1 - 3.2e-05 23.1 0.0 4.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 KII87375.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 KII87375.1 - 0.0028 17.0 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 KII87375.1 - 0.0065 15.3 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.9 KII87375.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KII87375.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 KII87375.1 - 0.065 12.6 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) EXS PF03124.9 KII87375.1 - 0.11 11.5 0.1 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 EXS family E1-E2_ATPase PF00122.15 KII87376.1 - 1.3e-50 171.6 2.8 3.3e-50 170.2 1.9 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KII87376.1 - 9.2e-38 130.8 1.9 1.5e-37 130.1 0.4 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KII87376.1 - 5.2e-25 87.3 0.0 2.6e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 KII87376.1 - 1.6e-08 34.9 0.1 5.3e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KII87376.1 - 0.0001 21.9 0.2 0.0068 16.0 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.7 KII87376.1 - 0.24 11.2 7.0 8.2 6.2 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) EHN PF06441.7 KII87377.1 - 6.5e-35 119.4 0.0 1.4e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII87377.1 - 1.6e-10 41.2 3.1 3.6e-10 40.1 2.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87377.1 - 1.2e-08 34.8 0.6 2.7e-07 30.3 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII87377.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family T2SF PF00482.18 KII87378.1 - 0.072 13.0 0.6 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F IncA PF04156.9 KII87379.1 - 0.1 12.1 17.6 0.2 11.2 12.2 1.4 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KII87379.1 - 0.31 10.8 19.7 1.7 8.4 4.2 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 KII87379.1 - 0.5 10.1 25.0 0.12 12.2 10.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KII87379.1 - 0.66 8.5 12.4 1.1 7.8 8.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 KII87379.1 - 3.2 6.9 26.1 4.3 6.5 14.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) V_ATPase_I PF01496.14 KII87379.1 - 5 4.8 6.0 6.9 4.3 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KII87379.1 - 8.1 5.3 12.4 15 4.4 8.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF676 PF05057.9 KII87380.1 - 1.3e-29 103.0 0.0 1.7e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KII87380.1 - 0.00039 20.0 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KII87380.1 - 0.016 15.0 1.2 0.045 13.6 0.9 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Coatomer_E PF04733.9 KII87381.1 - 2.8e-44 151.4 1.1 3.3e-44 151.2 0.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 KII87381.1 - 0.00069 19.3 0.6 5.3 7.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII87381.1 - 0.001 18.6 1.5 0.14 11.8 0.0 3.6 3 1 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 KII87381.1 - 0.066 13.0 1.6 1.1 9.1 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII87381.1 - 0.085 12.5 0.0 20 5.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII87381.1 - 0.22 11.8 7.5 6 7.2 0.1 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII87381.1 - 2.2 9.1 15.9 5.7 7.8 0.1 5.2 4 3 2 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KII87381.1 - 3.8 8.2 9.5 8.8 7.0 1.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat An_peroxidase PF03098.10 KII87382.1 - 2.4e-82 277.0 0.0 2.9e-80 270.1 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KII87382.1 - 7.1e-07 28.1 0.0 0.00048 18.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 DUF1726 PF08351.6 KII87382.1 - 0.035 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) F-box-like PF12937.2 KII87383.1 - 1.1e-07 31.5 0.3 1.1e-07 31.5 0.2 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KII87383.1 - 0.064 12.9 1.2 3.4 7.4 0.0 3.7 2 1 0 2 2 2 0 F-box domain PH_10 PF15411.1 KII87384.1 - 2.1e-27 95.5 0.0 3.7e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 KII87384.1 - 1.2e-05 24.9 2.2 4.5e-05 23.1 1.7 1.8 1 1 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 KII87384.1 - 2.9e-05 23.8 2.2 0.00081 19.1 0.0 3.4 3 1 0 3 3 3 1 von Willebrand factor type A domain zf-rbx1 PF12678.2 KII87384.1 - 0.00039 20.4 0.1 0.0029 17.6 0.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KII87384.1 - 0.017 14.7 0.4 0.043 13.4 0.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII87384.1 - 0.025 14.2 1.9 0.14 11.8 1.7 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII87384.1 - 0.06 13.3 1.7 0.15 12.0 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII87384.1 - 0.12 12.0 0.7 0.26 10.9 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PALP PF00291.20 KII87385.1 - 5e-53 180.3 1.6 5.7e-53 180.1 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Polyketide_cyc2 PF10604.4 KII87385.1 - 0.033 14.3 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DOPA_dioxygen PF08883.6 KII87386.1 - 2.3e-30 104.7 0.1 2.8e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family dCMP_cyt_deam_1 PF00383.17 KII87388.1 - 7.1e-20 70.5 0.1 9.9e-20 70.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KII87388.1 - 8.7e-13 48.3 0.2 1.1e-10 41.5 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KII87388.1 - 0.018 14.4 1.2 0.2 10.9 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases F-box-like PF12937.2 KII87389.1 - 1.7e-11 43.6 1.7 5.8e-11 41.9 1.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87389.1 - 0.49 10.1 4.3 0.77 9.4 1.0 2.9 2 1 0 2 2 2 0 F-box domain PIF1 PF05970.9 KII87390.1 - 1e-08 34.5 0.1 1.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 KII87390.1 - 5.5e-05 23.2 0.0 9.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KII87390.1 - 0.00016 21.3 0.1 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KII87390.1 - 0.0003 20.4 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KII87390.1 - 0.0014 17.8 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein UPF0079 PF02367.12 KII87390.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KII87390.1 - 0.0037 16.9 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KII87390.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KII87390.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase TrwB_AAD_bind PF10412.4 KII87390.1 - 0.011 14.3 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 KII87390.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KII87390.1 - 0.032 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KII87390.1 - 0.051 13.7 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KII87390.1 - 0.067 13.4 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 KII87390.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KII87390.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 KII87390.1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UvrD_C_2 PF13538.1 KII87392.1 - 0.0051 16.9 0.0 0.0071 16.4 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain F-box-like PF12937.2 KII87393.1 - 5.1e-12 45.3 1.7 2.1e-11 43.3 0.6 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII87393.1 - 0.0017 17.9 0.4 0.0058 16.2 0.3 2.0 1 0 0 1 1 1 1 F-box domain PI3_PI4_kinase PF00454.22 KII87395.1 - 1.1e-43 149.4 0.0 1.9e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KII87395.1 - 2.3e-27 95.6 0.0 5.4e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KII87395.1 - 1.3e-11 43.7 0.0 3.7e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 FATC domain Pkinase PF00069.20 KII87396.1 - 6.4e-72 241.8 0.0 8.5e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87396.1 - 2.7e-48 164.3 0.0 4.2e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KII87396.1 - 5.3e-22 77.9 1.9 8.7e-22 77.3 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KII87396.1 - 0.00048 19.1 0.0 0.00079 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII87396.1 - 0.014 15.1 0.1 0.15 11.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KII87396.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 KII87396.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain F-box-like PF12937.2 KII87398.1 - 1.2e-11 44.1 1.8 3.6e-11 42.5 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87398.1 - 0.15 11.7 6.4 1.2 8.9 2.9 3.1 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KII87399.1 - 2.8e-10 39.7 1.2 7e-10 38.4 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87399.1 - 2.7 7.7 8.2 2.9 7.6 2.9 3.0 2 1 0 2 2 2 0 F-box domain COesterase PF00135.23 KII87402.1 - 4.4e-93 312.7 0.1 7.1e-93 312.1 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII87402.1 - 6.9e-10 38.8 0.2 3.3e-09 36.6 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII87402.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.2 KII87403.1 - 3e-11 42.8 0.5 3e-11 42.8 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII87403.1 - 0.0014 18.2 0.5 0.0063 16.1 0.3 2.2 1 0 0 1 1 1 1 F-box domain LRR_7 PF13504.1 KII87403.1 - 0.066 13.4 2.4 89 3.9 0.0 4.8 4 0 0 4 4 4 0 Leucine rich repeat PseudoU_synth_1 PF01416.15 KII87405.1 - 1.4e-16 60.8 0.0 2.7e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase RNA_pol_Rpb4 PF03874.11 KII87406.1 - 4.6e-21 74.9 0.2 5.5e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2666 PF10869.3 KII87406.1 - 0.086 12.8 0.1 0.35 10.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Aa_trans PF01490.13 KII87407.1 - 6.6e-83 278.4 21.2 8.1e-83 278.1 14.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FGGY_N PF00370.16 KII87408.1 - 1.2e-24 87.0 0.0 8.9e-18 64.4 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KII87408.1 - 2.1e-16 60.1 0.0 4.6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Phage_holin_1 PF04531.8 KII87409.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage holin SUZ PF12752.2 KII87410.1 - 1.8e-17 63.5 1.5 3e-17 62.8 1.1 1.4 1 0 0 1 1 1 1 SUZ domain R3H PF01424.17 KII87410.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain SET PF00856.23 KII87412.1 - 1.9e-14 54.2 6.7 3.7e-14 53.3 1.2 3.1 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 KII87412.1 - 2.1e-14 53.6 4.7 2.1e-14 53.6 3.3 1.8 2 0 0 2 2 2 1 Pre-SET motif Pol_alpha_B_N PF08418.5 KII87412.1 - 0.27 10.7 16.7 0.42 10.1 11.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.4 KII87412.1 - 2.1 6.5 12.8 3.1 5.9 8.9 1.2 1 0 0 1 1 1 0 Transmembrane protein FMO-like PF00743.14 KII87413.1 - 7.4e-26 90.4 0.0 2.6e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII87413.1 - 8.1e-19 68.4 0.0 1.7e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII87413.1 - 2.1e-09 37.3 0.0 4.3e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KII87413.1 - 7.9e-09 34.8 0.1 4.9e-05 22.3 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KII87413.1 - 9e-07 28.8 0.0 2.4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KII87413.1 - 0.00012 22.3 0.3 0.06 13.7 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII87413.1 - 0.0013 17.7 0.4 0.03 13.2 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII87413.1 - 0.0017 18.2 0.0 0.46 10.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII87413.1 - 0.022 13.2 0.0 0.27 9.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 KII87413.1 - 0.038 14.2 0.1 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 KII87413.1 - 0.041 12.9 0.5 11 4.8 0.0 3.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 KII87413.1 - 0.17 11.4 0.0 21 4.6 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KII87413.1 - 0.18 10.8 0.0 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family PAT1 PF09770.4 KII87414.1 - 5.4 5.1 11.1 6.4 4.8 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 KII87415.1 - 2.7e-12 46.2 1.4 6.8e-12 44.9 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII87415.1 - 0.91 9.2 5.0 48 3.7 2.4 3.5 2 1 0 2 2 2 0 F-box domain Zds_C PF08632.5 KII87416.1 - 2.2e-22 78.1 0.2 3.8e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CAF-1_p150 PF11600.3 KII87416.1 - 0.02 14.2 34.9 0.011 15.0 11.4 2.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rnk_N PF14760.1 KII87416.1 - 0.21 11.6 3.9 0.29 11.2 0.2 2.4 2 0 0 2 2 2 0 Rnk N-terminus SAPS PF04499.10 KII87416.1 - 0.55 8.8 2.7 0.86 8.1 1.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.3 KII87416.1 - 0.75 8.4 15.9 0.092 11.4 0.9 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MOZART1 PF12554.3 KII87417.1 - 4.1e-24 83.7 0.3 5.2e-24 83.4 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1732 PF08340.6 KII87417.1 - 0.14 11.9 0.1 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Adaptin_N PF01602.15 KII87418.1 - 5.5e-144 480.3 7.8 6.5e-144 480.1 5.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KII87418.1 - 2.3e-22 79.4 0.2 6.8e-22 77.9 0.1 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KII87418.1 - 6.8e-07 29.4 4.3 0.12 12.6 0.1 5.3 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 KII87418.1 - 0.00061 19.6 3.6 0.071 12.9 0.8 3.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KII87418.1 - 0.002 18.0 2.9 19 5.6 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 KII87418.1 - 0.0087 15.6 1.2 0.04 13.4 0.2 2.4 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) RIX1 PF08167.7 KII87418.1 - 0.047 13.3 0.4 1.7 8.3 0.0 3.4 2 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Fork_head PF00250.13 KII87419.1 - 6.6e-20 70.9 0.0 1.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Fork head domain MSP1_C PF07462.6 KII87419.1 - 7.4 4.8 4.4 12 4.1 3.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus BRF1 PF07741.8 KII87419.1 - 8 6.7 9.1 1.4 9.1 0.2 2.8 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DNA_ligase_A_M PF01068.16 KII87420.1 - 1.6e-50 171.3 0.3 2.7e-50 170.5 0.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KII87420.1 - 4.7e-40 137.2 0.0 1.1e-39 136.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KII87420.1 - 5.7e-14 52.2 0.0 2e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KII87420.1 - 1.5e-08 34.6 0.1 0.015 15.4 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 KII87421.1 - 7.5e-74 248.1 0.0 1.1e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87421.1 - 3e-36 124.8 0.0 4.8e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII87421.1 - 0.018 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1168 PF06658.7 KII87421.1 - 0.027 14.0 1.0 0.045 13.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Kinase-like PF14531.1 KII87421.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF2962 PF11176.3 KII87422.1 - 5.1e-33 113.8 1.5 6.1e-33 113.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) SF3b1 PF08920.5 KII87423.1 - 2.2e-25 89.3 8.4 4.6e-23 81.8 5.8 2.8 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KII87423.1 - 4.2e-12 46.1 8.6 0.0001 22.4 0.0 7.1 5 2 3 8 8 8 2 HEAT repeats HEAT PF02985.17 KII87423.1 - 3.2e-11 42.3 7.5 0.069 13.2 0.0 10.0 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 KII87423.1 - 3.4e-09 36.9 4.8 0.047 14.1 0.0 8.2 6 2 2 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KII87423.1 - 4.1e-07 30.3 1.9 0.67 10.3 0.0 5.4 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KII87423.1 - 8.4e-06 24.3 2.5 0.053 11.8 0.0 3.4 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 KII87423.1 - 0.00051 19.4 0.4 9.1 5.5 0.0 4.5 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 KII87423.1 - 0.0032 16.8 1.9 3.3 6.9 0.0 3.7 3 1 1 4 4 4 2 CLASP N terminal Arm PF00514.18 KII87423.1 - 0.08 12.8 0.2 9.8 6.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KII87423.1 - 0.55 10.0 6.1 41 3.9 0.0 5.1 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 CTP_transf_2 PF01467.21 KII87425.1 - 1.9e-10 40.9 0.0 2.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase FNIP PF05725.7 KII87426.1 - 0.058 13.3 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 FNIP Repeat F-box-like PF12937.2 KII87427.1 - 0.0011 18.6 0.5 0.0026 17.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87427.1 - 0.071 12.7 0.3 0.27 10.9 0.2 1.9 1 1 0 1 1 1 0 F-box domain BTB PF00651.26 KII87428.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KII87429.1 - 8.7e-27 92.0 43.1 1.1e-08 34.8 0.1 7.7 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.21 KII87429.1 - 1.6e-19 68.9 54.5 6.7e-06 26.1 2.1 8.8 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII87429.1 - 8e-12 44.6 45.9 0.00023 21.2 0.8 8.6 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KII87429.1 - 2.3e-06 27.2 30.9 0.0077 16.1 0.6 6.7 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII87429.1 - 0.0031 17.5 19.7 0.05 13.7 0.9 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KII87429.1 - 0.0063 16.6 2.1 0.0063 16.6 1.5 6.4 7 0 0 7 7 7 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KII87429.1 - 0.011 15.7 1.5 0.011 15.7 1.0 4.7 4 2 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KII87429.1 - 0.08 13.1 0.9 0.08 13.1 0.6 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 KII87429.1 - 9.4 5.8 12.5 0.15 11.5 1.8 3.0 2 1 1 3 3 3 0 InsA N-terminal domain BTB PF00651.26 KII87430.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ADH_N PF08240.7 KII87431.1 - 7.1e-08 32.1 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII87431.1 - 4.7e-07 29.3 1.1 4.7e-07 29.3 0.7 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4562 PF15123.1 KII87431.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) DUF914 PF06027.7 KII87432.1 - 3.1e-105 351.7 10.4 3.8e-105 351.4 7.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DUF2798 PF11391.3 KII87432.1 - 0.01 15.5 3.0 1.1 9.1 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) UAA PF08449.6 KII87432.1 - 0.023 13.5 12.8 0.043 12.7 8.8 1.4 1 1 0 1 1 1 0 UAA transporter family Peptidase_M20 PF01546.23 KII87433.1 - 1.9e-07 30.7 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.23 KII87434.1 - 6.8e-25 87.6 0.1 9.4e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KII87434.1 - 1.8e-09 37.3 0.0 3.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KII87435.1 - 3.9e-27 94.9 0.0 5.5e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KII87435.1 - 3.1e-10 39.7 0.1 6.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Symplekin_C PF12295.3 KII87436.1 - 7.2e-58 195.5 0.2 1.8e-57 194.1 0.1 1.8 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 KII87436.1 - 1.7e-54 184.8 0.0 3.7e-54 183.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) V-ATPase_G PF03179.10 KII87437.1 - 1.9e-33 114.8 16.7 2.2e-33 114.6 11.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Bac_transf PF02397.11 KII87437.1 - 0.0085 15.2 0.1 0.013 14.6 0.0 1.4 1 1 0 1 1 1 1 Bacterial sugar transferase Glyco_transf_36 PF06165.6 KII87437.1 - 0.02 14.7 0.4 0.033 14.0 0.2 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 36 ATP-synt_B PF00430.13 KII87437.1 - 0.036 13.8 19.7 0.046 13.5 9.5 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Colicin-DNase PF12639.2 KII87437.1 - 0.054 13.7 0.4 0.085 13.1 0.3 1.4 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin TraC_F_IV PF11130.3 KII87437.1 - 0.073 12.4 0.6 0.096 12.1 0.4 1.3 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Nop25 PF09805.4 KII87437.1 - 0.074 13.1 8.8 0.094 12.7 6.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3535 PF12054.3 KII87437.1 - 0.19 10.3 4.0 0.24 10.0 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DUF3552 PF12072.3 KII87437.1 - 0.48 9.5 15.7 0.74 8.9 10.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) MMR1 PF08505.5 KII87437.1 - 1.4 8.9 4.1 1.6 8.6 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Seryl_tRNA_N PF02403.17 KII87437.1 - 3.1 7.8 9.2 10 6.2 6.3 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KII87437.1 - 3.5 7.1 8.4 9.9 5.7 5.8 1.8 1 1 0 1 1 1 0 IncA protein DUF16 PF01519.11 KII87437.1 - 8.8 6.6 8.7 1.5 9.0 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fungal_trans PF04082.13 KII87438.1 - 1.9e-20 72.8 0.4 2.8e-20 72.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII87438.1 - 1.5e-09 37.6 10.1 2.4e-09 36.9 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 KII87439.1 - 1.8e-29 101.9 10.8 2.1e-29 101.7 7.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 KII87440.1 - 1.7e-31 107.6 0.1 2.8e-31 106.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 KII87440.1 - 0.009 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH Methyltransf_25 PF13649.1 KII87441.1 - 1e-09 38.6 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII87441.1 - 0.0002 20.9 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII87441.1 - 0.019 15.5 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KII87441.1 - 0.039 14.4 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SNARE PF05739.14 KII87442.1 - 3.8e-08 32.9 0.1 5.2e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 SNARE domain DUF1515 PF07439.6 KII87442.1 - 0.075 12.8 0.2 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) PspA_IM30 PF04012.7 KII87443.1 - 0.091 12.1 5.6 0.12 11.6 3.9 1.1 1 0 0 1 1 1 0 PspA/IM30 family CENP-F_leu_zip PF10473.4 KII87443.1 - 0.13 12.0 6.0 0.18 11.6 4.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 KII87443.1 - 3.1 7.2 5.6 3.9 6.8 3.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RhoGAP PF00620.22 KII87444.1 - 2.8e-34 117.9 0.0 5.4e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KII87444.1 - 3.3e-28 97.5 38.8 3.7e-11 42.9 5.9 4.6 5 0 0 5 5 5 4 LIM domain BTB PF00651.26 KII87445.1 - 0.0012 18.7 0.1 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain GATA PF00320.22 KII87447.1 - 2.7e-13 49.0 1.4 4.7e-13 48.2 0.9 1.4 1 0 0 1 1 1 1 GATA zinc finger RhoGAP PF00620.22 KII87448.1 - 1.7e-11 43.9 0.0 4.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KII87448.1 - 1.7e-08 34.4 0.0 5.6e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KII87448.1 - 2.5e-07 30.3 0.0 4.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CHCH PF06747.8 KII87449.1 - 0.00016 21.5 4.9 0.00033 20.4 3.4 1.6 1 1 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 KII87449.1 - 0.0024 17.9 1.8 0.0024 17.9 1.2 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 KII87449.1 - 0.081 12.7 2.1 0.37 10.6 1.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 KII87449.1 - 0.088 12.8 7.0 0.52 10.4 1.8 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Filament PF00038.16 KII87450.1 - 0.0017 17.9 3.3 0.054 12.9 1.3 2.3 1 1 0 2 2 2 2 Intermediate filament protein DUF4226 PF10774.4 KII87450.1 - 0.043 13.8 1.6 0.12 12.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF2422 PF10337.4 KII87451.1 - 1.6e-75 254.7 0.6 1.6e-75 254.7 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KII87451.1 - 8.2e-31 107.3 0.0 2.3e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KII87451.1 - 4.4e-09 36.3 12.9 4.4e-09 36.3 8.9 3.6 3 0 0 3 3 3 2 Fusaric acid resistance protein-like DLH PF01738.13 KII87452.1 - 9.5e-21 74.0 0.0 1.1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.6 KII87452.1 - 7e-05 21.7 0.0 9.3e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KII87452.1 - 0.034 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 KII87452.1 - 0.053 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L37ae PF01780.14 KII87453.1 - 1.7e-40 136.7 10.3 1.9e-40 136.6 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KII87453.1 - 0.0041 16.8 1.7 0.0063 16.2 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 KII87453.1 - 0.0094 15.8 1.2 0.012 15.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-FCS PF06467.9 KII87453.1 - 0.049 13.2 1.7 0.83 9.3 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.10 KII87453.1 - 0.06 13.1 3.5 1.2 8.9 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 KII87453.1 - 0.12 12.0 2.9 0.22 11.2 2.0 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.5 KII87453.1 - 0.24 10.8 4.1 1 8.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Sec23_Sec24 PF04810.10 KII87453.1 - 0.27 10.8 1.4 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Ribosomal_L44 PF00935.14 KII87453.1 - 1.1 9.3 8.3 1.4 8.9 2.4 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 zf-H2C2_2 PF13465.1 KII87453.1 - 5.2 7.5 6.2 3.6 8.0 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain UCH PF00443.24 KII87454.1 - 1.3e-79 267.1 0.0 2.4e-79 266.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII87454.1 - 2.1e-19 70.0 0.0 8.6e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KII87454.1 - 1e-12 48.2 0.0 3.4e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 KII87454.1 - 0.043 13.2 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF1712 PF08217.6 KII87455.1 - 2.5e-18 65.6 0.0 3.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-CCCH PF00642.19 KII87456.1 - 2.5e-12 46.1 20.0 2.7e-05 23.7 0.7 4.9 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PPP4R2 PF09184.6 KII87456.1 - 0.73 9.3 14.0 1.4 8.4 9.7 1.4 1 0 0 1 1 1 0 PPP4R2 Nucleoplasmin PF03066.10 KII87456.1 - 2.2 7.7 18.7 3.6 7.1 13.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KII87456.1 - 4.8 7.4 23.5 11 6.3 16.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Defensin_beta PF00711.14 KII87456.1 - 7.5 6.5 12.3 0.081 12.8 0.7 3.1 3 0 0 3 3 3 0 Beta defensin AICARFT_IMPCHas PF01808.13 KII87457.1 - 2.6e-109 365.1 0.0 3.2e-109 364.8 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KII87457.1 - 1.1e-23 82.9 0.0 1.8e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.1 KII87458.1 - 2.7e-38 131.3 0.6 3.3e-38 131.0 0.4 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KII87458.1 - 3.4e-08 33.5 0.3 6.8e-08 32.5 0.2 1.5 1 1 0 1 1 1 1 HD domain EF-hand_4 PF12763.2 KII87458.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF383 PF04063.9 KII87460.1 - 1.4e-52 178.0 0.0 3.2e-52 176.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KII87460.1 - 5.7e-17 61.0 0.1 1.2e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Spt20 PF12090.3 KII87461.1 - 2e-34 118.5 0.0 2e-34 118.5 0.0 3.1 4 0 0 4 4 4 1 Spt20 family Phage_int_SAM_4 PF13495.1 KII87461.1 - 0.053 13.8 0.6 0.7 10.2 0.1 2.6 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Ribonucleas_3_3 PF14622.1 KII87462.1 - 1.8e-07 31.1 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KII87462.1 - 4.5e-07 30.3 0.0 8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 KII87462.1 - 0.00037 20.9 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain Pkinase PF00069.20 KII87463.1 - 7.4e-69 231.7 0.0 1e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87463.1 - 2.9e-32 111.7 0.0 4.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII87463.1 - 0.014 14.5 0.1 0.035 13.1 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII87463.1 - 0.029 14.0 2.1 0.17 11.6 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KII87463.1 - 0.08 11.8 0.0 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ParA PF10609.4 KII87464.1 - 3.1e-36 123.0 0.0 6.3e-36 122.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KII87464.1 - 6e-14 51.9 0.0 8.9e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KII87464.1 - 2.1e-05 23.7 0.7 0.0015 17.6 0.1 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KII87464.1 - 0.00013 21.3 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KII87464.1 - 0.00052 19.9 0.0 0.002 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KII87464.1 - 0.00053 19.2 0.0 0.32 10.1 0.0 2.5 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 KII87464.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MipZ PF09140.6 KII87464.1 - 0.019 14.0 0.0 0.1 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ AAA_19 PF13245.1 KII87464.1 - 0.027 14.1 0.5 1.7 8.4 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain YjeF_N PF03853.10 KII87464.1 - 0.045 13.3 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus YhjQ PF06564.7 KII87464.1 - 0.077 12.3 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 YhjQ protein AAA_29 PF13555.1 KII87464.1 - 0.093 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2752 PF10825.3 KII87464.1 - 0.1 12.6 0.2 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) AAA_17 PF13207.1 KII87464.1 - 0.11 13.3 0.1 1.5 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KII87464.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain VirE PF05272.6 KII87464.1 - 0.19 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E DLH PF01738.13 KII87465.1 - 1.6e-22 79.9 0.0 1.8e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII87465.1 - 4.8e-07 29.6 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII87465.1 - 0.00057 19.8 0.0 0.00065 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII87465.1 - 0.019 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 KII87466.1 - 6.3e-19 68.1 0.0 7.4e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII87466.1 - 0.00022 21.0 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII87466.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 KII87467.1 - 7.7e-22 77.6 0.0 8.8e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII87467.1 - 4.1e-06 26.6 0.0 7.4e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGA_cap PF09587.5 KII87467.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Abhydrolase_6 PF12697.2 KII87467.1 - 0.0023 17.8 0.0 0.0072 16.2 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII87467.1 - 0.043 13.3 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KII87470.1 - 2.2e-22 79.4 0.0 2.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII87470.1 - 6.2e-05 22.7 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII87470.1 - 0.0028 16.5 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 KII87470.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII87470.1 - 0.01 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dak1 PF02733.12 KII87471.1 - 6.7e-113 376.5 2.2 9.4e-113 376.0 1.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KII87471.1 - 3.6e-38 130.9 4.5 3.6e-38 130.9 3.1 1.5 2 0 0 2 2 2 1 DAK2 domain Tim44 PF04280.10 KII87472.1 - 6e-32 110.6 0.4 9.1e-31 106.8 0.0 2.5 3 0 0 3 3 3 1 Tim44-like domain Sigma54_CBD PF04963.8 KII87472.1 - 0.048 13.0 0.0 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain LytR_C PF13399.1 KII87472.1 - 0.068 13.5 1.2 16 5.9 0.1 2.6 1 1 1 2 2 2 0 LytR cell envelope-related transcriptional attenuator DUF1778 PF08681.6 KII87472.1 - 0.52 10.1 5.6 5.2 6.9 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1778) T2SF PF00482.18 KII87472.1 - 1.2 9.0 3.7 1.4 8.7 1.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F WD40 PF00400.27 KII87473.1 - 6.8e-14 51.1 0.1 5.9e-05 22.7 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat CPSF_A PF03178.10 KII87473.1 - 0.0044 16.1 0.0 0.014 14.5 0.0 1.7 1 1 1 2 2 2 1 CPSF A subunit region Rubella_Capsid PF05750.6 KII87473.1 - 0.11 11.8 7.3 0.18 11.1 5.0 1.2 1 0 0 1 1 1 0 Rubella capsid protein GFO_IDH_MocA PF01408.17 KII87474.1 - 7.9e-23 81.2 0.1 1.9e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII87474.1 - 2.1e-06 27.5 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_47 PF01532.15 KII87475.1 - 1.9e-130 435.5 0.0 2.2e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.8 KII87476.1 - 1.9e-28 98.1 1.4 2e-28 98.1 0.2 1.5 2 0 0 2 2 2 1 Erv1 / Alr family DAZAP2 PF11029.3 KII87476.1 - 0.099 13.1 3.1 0.17 12.3 2.2 1.4 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Zip PF02535.17 KII87477.1 - 1.6e-53 181.8 11.0 1.8e-53 181.6 7.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-HIT PF04438.11 KII87478.1 - 7.4e-09 35.1 11.1 1.5e-08 34.0 7.7 1.5 1 0 0 1 1 1 1 HIT zinc finger DEAD PF00270.24 KII87479.1 - 3.7e-37 127.3 0.1 5.7e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII87479.1 - 1e-19 70.1 0.1 2.8e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KII87479.1 - 0.0018 18.1 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KII87479.1 - 0.053 12.5 1.6 0.079 12.0 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Mitofilin PF09731.4 KII87479.1 - 3.5 6.1 7.8 0.17 10.4 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial inner membrane protein FGGY_C PF02782.11 KII87480.1 - 2.9e-59 200.0 3.3 4.4e-59 199.4 2.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KII87480.1 - 4.5e-58 196.4 0.0 1.1e-56 191.8 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_hydro_47 PF01532.15 KII87481.1 - 2.7e-130 435.0 0.0 3.2e-130 434.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ANTH PF07651.11 KII87482.1 - 1.1e-50 171.9 0.0 1.5e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.6 KII87482.1 - 3.6e-09 36.5 40.9 3.6e-09 36.5 28.3 8.9 1 1 2 3 3 3 2 Domain of unknown function (DUF1720) ENTH PF01417.15 KII87482.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 ENTH domain SHNi-TPR PF10516.4 KII87483.1 - 1.1e-14 53.3 0.1 5.1e-13 48.0 0.0 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 KII87483.1 - 1.5e-12 47.2 4.5 8.3e-06 25.6 0.9 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII87483.1 - 2.9e-12 46.0 0.6 7e-05 22.3 0.3 2.7 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KII87483.1 - 6.3e-06 25.5 5.2 0.036 13.6 1.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII87483.1 - 6.4e-06 25.6 5.0 0.18 11.8 0.0 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII87483.1 - 0.0001 22.8 4.2 0.04 14.6 0.5 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KII87483.1 - 0.00023 21.0 0.3 0.32 10.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII87483.1 - 0.0019 18.5 6.1 1.3 9.3 0.9 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII87483.1 - 0.0024 17.5 0.8 4.9 7.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII87483.1 - 0.005 16.5 2.7 1.1 9.1 0.2 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat Sec5 PF15469.1 KII87483.1 - 0.049 13.3 0.8 6.5 6.4 0.0 2.9 2 1 1 3 3 3 0 Exocyst complex component Sec5 TPR_14 PF13428.1 KII87483.1 - 0.088 13.4 4.6 7.7 7.4 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 KII87483.1 - 2.3 8.1 7.1 0.64 9.8 1.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.17 KII87484.1 - 1.1e-11 43.7 3.2 3.7e-10 38.7 1.4 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 KII87484.1 - 0.084 12.0 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Paf1 PF03985.8 KII87485.1 - 6.3e-61 206.4 0.0 7.7e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Paf1 Ribosomal_S4e PF00900.15 KII87486.1 - 1.5e-30 104.6 0.1 3.3e-30 103.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KII87486.1 - 5.6e-21 74.1 4.5 1.2e-20 72.9 2.8 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 KII87486.1 - 2.3e-07 30.1 0.1 4.4e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KII87486.1 - 2.8e-05 23.6 3.2 9.2e-05 22.0 2.3 2.0 1 0 0 1 1 1 1 KOW motif TPT PF03151.11 KII87487.1 - 2.5e-31 108.4 6.5 2.5e-31 108.4 4.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KII87487.1 - 1.6e-15 56.7 18.8 2.1e-15 56.4 13.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KII87487.1 - 7.7e-09 35.6 33.6 4.1e-07 30.0 7.9 3.5 2 1 1 3 3 3 2 EamA-like transporter family TrkH PF02386.11 KII87488.1 - 7.7e-90 301.0 11.5 1.6e-87 293.3 0.9 2.1 2 0 0 2 2 2 2 Cation transport protein DRMBL PF07522.9 KII87489.1 - 1e-28 99.5 0.0 1.9e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KII87489.1 - 1.1e-10 41.4 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HECT PF00632.20 KII87490.1 - 8.6e-80 268.2 0.0 1.3e-79 267.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Aminotran_3 PF00202.16 KII87490.1 - 2.5e-66 223.8 0.1 4.3e-66 223.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Arm PF00514.18 KII87490.1 - 0.0034 17.1 1.2 0.24 11.3 0.0 4.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat GM_CSF PF01109.12 KII87490.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor GST_N_3 PF13417.1 KII87491.1 - 1.5e-13 50.7 0.0 3.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KII87491.1 - 7.6e-12 45.2 0.0 1.9e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII87491.1 - 4.3e-09 36.2 0.0 8.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII87491.1 - 0.056 13.9 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex2_Pex12 PF04757.9 KII87491.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region GST_C_2 PF13410.1 KII87491.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII87491.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol_alpha_N PF12254.3 KII87492.1 - 6.6e-05 22.6 4.4 0.00017 21.3 3.1 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF3384 PF11864.3 KII87492.1 - 0.015 13.7 0.4 0.017 13.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) CRAL_TRIO PF00650.15 KII87493.1 - 1e-24 86.8 0.0 1.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KII87493.1 - 0.001 19.1 0.0 0.0035 17.4 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain HABP4_PAI-RBP1 PF04774.10 KII87493.1 - 0.034 14.6 5.3 0.065 13.7 3.7 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Prok_Ub PF14454.1 KII87493.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Ubiquitin ZZ PF00569.12 KII87495.1 - 7.4e-18 63.8 61.1 5.8e-08 32.1 1.7 6.3 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.19 KII87495.1 - 3.1e-05 23.5 0.0 7.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Yippee-Mis18 PF03226.9 KII87495.1 - 0.03 14.3 0.0 0.03 14.3 0.0 4.3 3 1 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PAT1 PF09770.4 KII87497.1 - 5.2 5.1 9.5 6.5 4.8 6.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KII87497.1 - 7.6 5.8 11.0 9.6 5.4 7.6 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KII87498.1 - 1.2e-15 57.4 0.0 3.8e-06 26.2 0.0 3.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII87498.1 - 3.2e-06 26.4 0.2 0.06 12.4 0.0 2.7 3 1 0 3 3 3 2 Protein tyrosine kinase HCV_NS5a_1a PF08300.8 KII87498.1 - 0.027 14.3 0.1 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain DrrA_P4M PF14860.1 KII87498.1 - 0.17 11.6 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Tmemb_14 PF03647.8 KII87500.1 - 1.4e-17 63.8 8.1 1.6e-17 63.6 5.6 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C MtrC PF04211.8 KII87500.1 - 0.024 13.7 3.2 0.025 13.6 2.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C DUF2416 PF10315.4 KII87500.1 - 0.056 13.6 1.8 0.23 11.7 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) NAD_binding_4 PF07993.7 KII87501.1 - 1.7e-37 128.6 0.0 3.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII87501.1 - 1.3e-30 106.1 0.0 2e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KII87501.1 - 5.3e-08 32.5 0.0 8.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII87501.1 - 2.1e-05 23.3 0.0 3.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KII87501.1 - 0.0015 18.4 0.2 0.013 15.3 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KII87501.1 - 0.0037 17.4 0.2 0.014 15.6 0.2 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 KII87501.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KII87501.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DSPc PF00782.15 KII87502.1 - 2.1e-28 98.5 0.0 2.8e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII87502.1 - 0.00044 19.6 0.0 0.00056 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KII87502.1 - 0.00044 19.7 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 KII87502.1 - 0.024 14.8 0.1 0.11 12.7 0.0 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family Myotub-related PF06602.9 KII87502.1 - 0.17 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Med4 PF10018.4 KII87503.1 - 2.8e-23 82.2 0.1 4.4e-23 81.6 0.0 1.3 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.17 KII87503.1 - 0.033 14.2 1.4 0.08 12.9 1.0 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Voltage_CLC PF00654.15 KII87504.1 - 7.7e-85 285.0 29.7 1e-84 284.6 17.3 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 KII87504.1 - 2.8e-09 36.6 0.6 0.0029 17.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain MMS19_C PF12460.3 KII87506.1 - 1.8e-101 339.9 0.1 7e-101 337.9 0.0 1.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KII87506.1 - 3.9e-88 295.1 0.0 5.5e-86 288.0 0.0 3.0 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 KII87506.1 - 7.4e-06 26.2 11.7 0.04 14.4 0.3 6.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 KII87506.1 - 0.016 15.4 9.4 0.28 11.4 0.3 5.8 5 1 1 6 6 6 0 HEAT repeats Arm PF00514.18 KII87506.1 - 0.21 11.4 1.4 45 4.0 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KII87506.1 - 2.6 8.3 8.0 27 5.1 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat Methyltransf_28 PF02636.12 KII87507.1 - 5.5e-37 127.5 0.0 8.2e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 KII87507.1 - 0.0082 16.6 0.0 0.051 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 KII87507.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Orexin_rec2 PF03827.8 KII87508.1 - 0.063 13.3 0.9 10 6.2 0.1 2.3 2 0 0 2 2 2 0 Orexin receptor type 2 MBOAT_2 PF13813.1 KII87509.1 - 1.4e-21 76.3 2.2 1.4e-21 76.3 1.5 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Methyltransf_11 PF08241.7 KII87510.1 - 1.1e-09 38.6 0.0 2.8e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII87510.1 - 1.2e-08 35.5 0.0 1.7e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII87510.1 - 3.6e-08 33.1 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII87510.1 - 2.3e-06 27.8 0.0 3.9e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII87510.1 - 5.3e-06 26.8 0.0 8.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII87510.1 - 3.4e-05 23.5 0.0 0.00013 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KII87510.1 - 0.003 16.9 0.0 0.0061 15.9 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KII87510.1 - 0.026 13.6 0.2 0.33 10.0 0.2 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PQ-loop PF04193.9 KII87511.1 - 2.6e-32 110.1 8.0 7.4e-18 63.8 1.0 2.8 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KII87511.1 - 5.4e-06 26.1 1.4 0.042 13.7 0.3 2.6 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Shisa PF13908.1 KII87511.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Bax1-I PF01027.15 KII87511.1 - 0.073 12.6 5.1 0.25 10.9 3.9 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4231 PF14015.1 KII87511.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PQ-loop PF04193.9 KII87512.1 - 4.2e-29 99.8 9.3 1.5e-17 62.8 1.2 2.7 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KII87512.1 - 0.02 14.7 7.3 0.39 10.6 0.6 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF2474 PF10617.4 KII87512.1 - 0.43 10.2 4.0 0.48 10.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Kei1 PF08552.6 KII87513.1 - 4.1e-42 143.9 5.5 5.2e-42 143.6 3.8 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 KII87513.1 - 0.0038 17.1 4.2 0.0064 16.4 2.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4199) IF4E PF01652.13 KII87514.1 - 3e-46 156.9 0.4 3.6e-46 156.7 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelR PF01641.13 KII87515.1 - 7.4e-54 180.7 0.0 8.4e-54 180.5 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 KII87515.1 - 0.0052 16.6 1.4 0.26 11.1 0.1 2.9 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.1 KII87515.1 - 0.022 14.2 1.3 4.4 6.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 KII87515.1 - 0.023 14.6 0.7 0.39 10.7 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KII87515.1 - 0.029 14.0 0.1 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 KII87515.1 - 0.075 12.9 0.3 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KII87515.1 - 0.096 11.9 1.7 6.8 6.0 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 KII87515.1 - 0.16 12.0 0.9 1 9.4 0.6 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 KII87515.1 - 0.29 10.9 4.0 3.6 7.4 0.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.14 KII87515.1 - 1.2 9.0 5.0 2.5 7.9 0.7 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e DNA_RNApol_7kD PF03604.8 KII87515.1 - 1.6 8.3 5.7 13 5.3 0.3 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Nudix_N_2 PF14803.1 KII87515.1 - 3.8 7.2 5.4 84 2.9 0.3 3.6 4 0 0 4 4 4 0 Nudix N-terminal Tropomyosin_1 PF12718.2 KII87516.1 - 8.3e-46 155.3 31.9 9.7e-46 155.1 22.1 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KII87516.1 - 2.4e-12 46.4 30.9 4.1e-07 29.3 10.9 2.9 1 1 1 2 2 2 2 Tropomyosin Myosin_tail_1 PF01576.14 KII87516.1 - 6.4e-05 20.8 31.4 7.4e-05 20.6 21.8 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.4 KII87516.1 - 0.0028 17.5 30.7 0.0034 17.2 5.2 2.8 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.1 KII87516.1 - 0.0044 14.7 25.5 0.006 14.3 17.7 1.2 1 0 0 1 1 1 1 AAA domain GAS PF13851.1 KII87516.1 - 0.0084 15.3 30.6 0.04 13.1 13.7 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 KII87516.1 - 0.025 14.5 32.0 0.23 11.4 8.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.3 KII87516.1 - 0.025 14.4 26.2 1.8 8.4 2.4 3.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 KII87516.1 - 0.028 12.9 31.4 0.072 11.5 21.7 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ERM PF00769.14 KII87516.1 - 0.039 13.4 32.0 0.015 14.8 19.6 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 KII87516.1 - 0.041 13.4 24.4 0.064 12.8 16.9 1.4 1 1 0 1 1 1 0 IncA protein DBI_PRT PF02277.12 KII87516.1 - 0.058 12.4 0.6 0.091 11.8 0.4 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase Laminin_II PF06009.7 KII87516.1 - 0.069 12.8 15.7 1.2 8.8 6.5 2.5 1 1 1 2 2 2 0 Laminin Domain II TAFH PF07531.9 KII87516.1 - 0.07 12.7 1.2 0.2 11.2 0.8 1.7 1 0 0 1 1 1 0 NHR1 homology to TAF APG6 PF04111.7 KII87516.1 - 0.094 11.7 31.5 0.047 12.7 12.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF869 PF05911.6 KII87516.1 - 0.13 10.4 22.0 0.17 10.0 15.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Transketolase_N PF00456.16 KII87516.1 - 0.24 10.1 8.0 0.3 9.8 5.6 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Flagellin_C PF00700.16 KII87516.1 - 0.27 11.3 5.4 2.2 8.4 0.2 2.6 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region FliD_C PF07195.7 KII87516.1 - 0.42 9.8 15.6 1 8.6 4.9 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus BicD PF09730.4 KII87516.1 - 0.42 8.8 24.2 0.47 8.7 16.7 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D NAD_binding_4 PF07993.7 KII87516.1 - 0.45 9.4 6.4 3.1 6.6 0.5 2.2 2 0 0 2 2 2 0 Male sterility protein DUF1664 PF07889.7 KII87516.1 - 0.46 10.2 15.3 0.15 11.8 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KII87516.1 - 0.52 10.4 21.9 1.7 8.7 5.4 3.0 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 KII87516.1 - 0.58 7.4 27.3 0.78 6.9 18.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4201 PF13870.1 KII87516.1 - 0.66 9.3 26.0 2.3 7.6 11.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2422 PF10337.4 KII87516.1 - 0.68 8.6 7.3 0.77 8.4 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Nup54 PF13874.1 KII87516.1 - 0.87 9.2 19.8 0.17 11.5 4.0 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 AAA_13 PF13166.1 KII87516.1 - 0.99 7.7 24.9 0.56 8.6 9.1 1.9 1 1 1 2 2 2 0 AAA domain Sec2p PF06428.6 KII87516.1 - 1 9.2 23.9 0.086 12.6 5.6 3.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Striatin PF08232.7 KII87516.1 - 1.2 9.4 22.5 0.12 12.6 9.9 2.3 1 1 1 2 2 2 0 Striatin family Phage_GP20 PF06810.6 KII87516.1 - 1.3 8.4 27.9 0.66 9.4 9.2 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 KII87516.1 - 1.6 8.4 30.8 2.2 8.0 10.0 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 KII87516.1 - 1.7 8.4 16.4 0.91 9.2 2.0 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) EzrA PF06160.7 KII87516.1 - 1.8 6.6 24.5 2.2 6.3 10.6 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 KII87516.1 - 1.8 8.6 17.9 2.4 8.2 3.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 KII87516.1 - 2.2 7.7 25.8 4.7 6.7 7.2 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uds1 PF15456.1 KII87516.1 - 2.3 8.2 22.3 3.4 7.6 4.0 2.5 1 1 1 2 2 2 0 Up-regulated During Septation TMF_DNA_bd PF12329.3 KII87516.1 - 2.3 8.0 36.6 0.46 10.3 12.4 3.6 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 KII87516.1 - 2.8 7.9 26.6 0.68 9.9 11.6 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 KII87516.1 - 2.9 7.0 24.3 1.2 8.3 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Laminin_I PF06008.9 KII87516.1 - 2.9 7.1 23.6 1.1 8.5 4.4 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF724 PF05266.9 KII87516.1 - 3.4 7.2 26.0 4.5 6.8 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.3 KII87516.1 - 3.6 7.3 24.7 4.6 7.0 9.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 KII87516.1 - 3.6 7.9 22.7 0.24 11.7 5.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Adeno_PIX PF03955.9 KII87516.1 - 3.8 8.0 12.2 1.7 9.2 2.0 2.7 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF3287 PF11690.3 KII87516.1 - 4.7 7.3 10.3 3.3 7.8 2.4 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3287) DUF4164 PF13747.1 KII87516.1 - 6.4 6.9 25.1 6.4 6.9 7.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) HTH_WhiA PF02650.9 KII87516.1 - 6.7 7.1 7.6 1.3 9.4 2.1 2.1 2 1 0 2 2 2 0 WhiA C-terminal HTH domain Ax_dynein_light PF10211.4 KII87516.1 - 6.8 6.4 25.9 3 7.6 7.1 2.7 1 1 2 3 3 3 0 Axonemal dynein light chain LMBR1 PF04791.11 KII87516.1 - 7.2 5.0 13.9 0.47 8.9 3.5 2.0 1 1 0 2 2 2 0 LMBR1-like membrane protein Bacillus_HBL PF05791.6 KII87516.1 - 7.4 5.8 18.6 0.11 11.8 2.8 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fmp27_WPPW PF10359.4 KII87516.1 - 7.9 4.7 21.9 3.1 6.1 5.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ATG16 PF08614.6 KII87516.1 - 9 6.0 27.0 1.8 8.3 6.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.8 KII87516.1 - 9.1 6.1 24.6 21 5.0 3.6 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PilJ PF13675.1 KII87516.1 - 9.6 6.5 13.2 6.9 7.0 2.3 2.8 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term NPV_P10 PF05531.7 KII87516.1 - 9.6 6.5 10.6 9.2 6.5 0.6 3.0 2 2 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF2408 PF10303.4 KII87517.1 - 2.2e-60 202.6 0.1 2.5e-34 118.2 0.0 5.1 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 KII87517.1 - 0.0054 17.0 6.5 7 7.0 0.1 5.1 5 1 0 5 5 5 1 Snapin/Pallidin MscS_porin PF12795.2 KII87517.1 - 0.028 13.7 2.9 13 4.9 0.1 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain MitMem_reg PF13012.1 KII87517.1 - 0.053 13.6 1.4 1.5 8.9 0.1 3.4 4 1 0 4 4 4 0 Maintenance of mitochondrial structure and function Fez1 PF06818.10 KII87517.1 - 0.062 13.3 2.0 0.18 11.7 1.4 1.8 1 1 0 1 1 1 0 Fez1 Med9 PF07544.8 KII87517.1 - 0.1 12.3 1.8 5.8 6.7 0.1 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 KII87517.1 - 0.1 12.4 2.4 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 KII87517.1 - 0.12 10.7 5.8 0.044 12.2 1.1 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light FUSC PF04632.7 KII87517.1 - 0.17 10.2 1.1 0.24 9.7 0.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 KII87517.1 - 1.6 9.1 4.5 21 5.5 0.2 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 KII87517.1 - 4 7.1 6.1 25 4.6 0.0 3.5 4 0 0 4 4 4 0 Laminin Domain II ATP-synt_ab PF00006.20 KII87518.1 - 3.5e-70 235.8 0.0 5.1e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KII87518.1 - 2.8e-22 79.3 0.0 7.5e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KII87518.1 - 7.7e-18 64.4 1.5 2e-17 63.1 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.16 KII87519.1 - 3.1e-13 49.6 0.1 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SPOR PF05036.8 KII87519.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Sporulation related domain FF PF01846.14 KII87520.1 - 1.4e-34 117.8 7.4 1.7e-12 47.0 0.0 6.2 5 1 1 6 6 6 5 FF domain WW PF00397.21 KII87520.1 - 5.8e-15 54.8 15.7 6.2e-09 35.5 2.1 2.7 2 0 0 2 2 2 2 WW domain Brix PF04427.13 KII87521.1 - 4.7e-42 143.8 0.0 7.1e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain EMP24_GP25L PF01105.19 KII87522.1 - 2.5e-50 170.7 0.1 2.8e-50 170.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ADH_zinc_N PF00107.21 KII87523.1 - 1.5e-12 47.1 0.0 2.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII87523.1 - 0.00022 20.9 0.0 0.00063 19.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_C30 PF05409.8 KII87523.1 - 0.042 12.9 0.1 0.07 12.1 0.1 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 DDE_3 PF13358.1 KII87524.1 - 1.5e-13 50.7 0.0 1.1e-12 47.9 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease GTP1_OBG PF01018.17 KII87528.1 - 0.12 12.0 2.4 0.12 12.0 0.9 1.6 1 1 0 2 2 2 0 GTP1/OBG RCR PF12273.3 KII87528.1 - 1.2 9.7 5.0 1.2 9.6 3.5 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Daxx PF03344.10 KII87528.1 - 1.6 7.1 13.6 1.6 7.1 9.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KII87528.1 - 5.1 5.0 13.3 5.2 4.9 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KII87530.1 - 0.24 10.9 14.0 0.035 13.7 3.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 KII87530.1 - 2.5 8.3 11.3 5.9 7.1 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3291 PF11695.3 KII87532.1 - 0.053 12.9 0.8 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) Cauli_VI PF01693.11 KII87533.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Retinal PF15449.1 KII87533.1 - 0.0012 16.5 6.1 0.0013 16.5 4.2 1.1 1 0 0 1 1 1 1 Retinal protein Tet_JBP PF12851.2 KII87535.1 - 0.00028 20.2 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-B_box PF00643.19 KII87536.1 - 0.083 12.7 10.1 0.019 14.8 4.3 2.0 2 0 0 2 2 2 0 B-box zinc finger Glyco_hydro_48 PF02011.10 KII87539.1 - 0.037 12.1 0.0 0.053 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Tet_JBP PF12851.2 KII87540.1 - 1.3e-05 24.6 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily GST_C_2 PF13410.1 KII87542.1 - 0.013 15.4 0.2 0.066 13.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain UBN2_2 PF14227.1 KII87544.1 - 4e-10 39.2 0.0 5.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII87544.1 - 3.1e-07 30.2 0.0 4.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII87544.1 - 0.025 14.5 5.0 0.039 13.9 3.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KII87544.1 - 0.49 9.9 4.4 0.99 8.9 3.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger UBN2_2 PF14227.1 KII87545.1 - 1.6e-09 37.3 0.0 2.7e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII87545.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_29 PF13551.1 KII87547.1 - 1.2e-07 31.9 0.0 1.7e-07 31.3 0.0 1.2 1 1 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 KII87547.1 - 3e-07 29.8 0.1 4.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 KII87547.1 - 4.1e-06 26.2 0.5 5.9e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KII87547.1 - 4.4e-06 27.3 0.2 0.005 17.6 0.0 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.1 KII87547.1 - 5.4e-06 26.3 0.5 6.9e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.10 KII87547.1 - 0.00077 19.2 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 KII87547.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 KII87547.1 - 0.0016 17.6 0.1 0.0029 16.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.14 KII87547.1 - 0.0087 15.7 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.1 KII87547.1 - 0.013 14.6 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 KII87547.1 - 0.034 13.7 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain LacI PF00356.16 KII87547.1 - 0.081 12.5 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_Tc3_2 PF01498.13 KII87547.1 - 0.09 12.8 0.0 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Transposase HTH_22 PF13309.1 KII87547.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_17 PF12728.2 KII87547.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.1 KII87547.1 - 0.12 12.5 0.5 0.16 12.2 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain UBN2_2 PF14227.1 KII87549.1 - 4.5e-11 42.3 0.0 5.6e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII87549.1 - 7e-08 32.2 0.0 9.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 KII87549.1 - 0.053 13.5 0.0 0.088 12.8 0.0 1.4 1 1 0 1 1 1 0 Retrotransposon gag protein PUD PF03714.9 KII87550.1 - 0.05 13.7 0.3 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial pullanase-associated domain LRR_8 PF13855.1 KII87550.1 - 0.13 12.0 0.4 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Leucine rich repeat PilJ PF13675.1 KII87551.1 - 0.021 15.1 3.3 0.032 14.5 0.5 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Zn_clus PF00172.13 KII87551.1 - 0.071 13.0 8.2 0.6 10.0 2.1 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1493 PF07377.7 KII87552.1 - 0.19 11.8 1.7 0.27 11.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Dimer_Tnp_hAT PF05699.9 KII87553.1 - 2.2e-13 49.6 0.0 2.3e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region WW PF00397.21 KII87562.1 - 4.3e-05 23.2 0.1 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 WW domain DUF4554 PF15091.1 KII87563.1 - 0.045 12.4 2.7 0.023 13.4 0.5 1.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4554) Herpes_pp85 PF04637.7 KII87563.1 - 5.4 5.1 5.0 6.7 4.8 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WW PF00397.21 KII87564.1 - 0.02 14.7 0.7 0.02 14.7 0.5 2.7 2 0 0 2 2 2 0 WW domain NDUFA12 PF05071.11 KII87565.1 - 3.8e-12 46.6 0.1 3.8e-12 46.6 0.1 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Meth_synt_2 PF01717.13 KII87566.1 - 5.8e-11 41.9 0.0 0.00018 20.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KII87566.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain PCI PF01399.22 KII87567.1 - 1.6e-20 73.3 0.0 6.3e-20 71.4 0.0 2.1 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.6 KII87567.1 - 1.6e-18 66.8 0.3 6.6e-18 64.8 0.2 2.1 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 KII87567.1 - 0.0065 16.2 0.2 0.0065 16.2 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII87567.1 - 0.0079 16.1 6.0 1.4 8.9 1.4 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KII87567.1 - 0.014 15.0 0.1 0.05 13.2 0.1 2.0 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 KII87567.1 - 0.059 14.0 8.1 2.2 9.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat OKR_DC_1_C PF03711.10 KII87567.1 - 0.066 13.2 0.1 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, C-terminal domain MFS_1 PF07690.11 KII87568.1 - 9.7e-31 106.7 33.9 9.7e-31 106.7 23.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PHD PF00628.24 KII87569.1 - 5.1e-09 35.6 0.3 9.1e-09 34.8 0.2 1.4 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.19 KII87569.1 - 6.8e-09 35.2 0.2 1.3e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PhnA_Zn_Ribbon PF08274.7 KII87569.1 - 0.031 14.0 1.6 0.069 12.9 1.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Prok-RING_1 PF14446.1 KII87569.1 - 0.8 9.4 3.6 0.42 10.3 0.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 APC_crr PF05923.7 KII87569.1 - 1.7 8.3 6.4 4.4 7.0 4.4 1.7 1 0 0 1 1 1 0 APC cysteine-rich region WW PF00397.21 KII87570.1 - 0.00047 19.9 3.2 0.0023 17.7 0.1 2.5 2 0 0 2 2 2 1 WW domain Sec20 PF03908.8 KII87571.1 - 2.9e-18 65.3 0.9 2.9e-18 65.3 0.6 2.2 2 1 1 3 3 3 1 Sec20 Chromo PF00385.19 KII87572.1 - 1.8e-07 30.7 0.3 2.9e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KII87572.1 - 2.5e-06 27.0 6.6 5.5e-06 25.9 4.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KII87572.1 - 0.57 9.5 6.0 1.1 8.6 4.2 1.4 1 0 0 1 1 1 0 PHD-finger Ribophorin_II PF05817.9 KII87573.1 - 3.9e-35 121.1 0.0 4.7e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.15 KII87574.1 - 3.8e-126 421.4 0.0 4.3e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 KII87574.1 - 0.0059 16.0 1.0 0.57 9.5 0.2 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 DUF1832 PF08870.6 KII87574.1 - 0.012 15.2 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1832) AhpC-TSA PF00578.16 KII87575.1 - 0.12 12.0 0.1 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family OrfB_Zn_ribbon PF07282.6 KII87575.1 - 9.8 5.9 7.4 2.1 8.0 0.3 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Syntaxin-6_N PF09177.6 KII87576.1 - 9.3e-23 80.4 3.1 4.2e-22 78.3 0.2 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KII87576.1 - 3.2e-13 49.1 4.9 9.4e-13 47.6 1.4 2.4 2 1 0 2 2 2 1 SNARE domain FliJ PF02050.11 KII87576.1 - 0.0035 17.3 2.2 1.1 9.3 0.0 2.8 2 2 1 3 3 3 2 Flagellar FliJ protein HisKA_3 PF07730.8 KII87576.1 - 0.06 13.6 0.2 0.06 13.6 0.2 2.9 2 1 0 2 2 2 0 Histidine kinase PspA_IM30 PF04012.7 KII87576.1 - 0.079 12.3 5.0 0.44 9.8 0.5 2.4 2 0 0 2 2 2 0 PspA/IM30 family DUF3040 PF11239.3 KII87576.1 - 0.11 12.5 0.3 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Mnd1 PF03962.10 KII87576.1 - 0.13 11.8 3.8 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Mnd1 family Laminin_I PF06008.9 KII87576.1 - 0.16 11.2 4.4 0.8 8.9 0.5 2.4 2 0 0 2 2 2 0 Laminin Domain I Reo_sigmaC PF04582.7 KII87576.1 - 0.2 10.8 0.8 1.1 8.3 0.2 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 KII87576.1 - 0.23 10.3 1.3 2.8 6.7 0.9 2.1 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 KII87576.1 - 0.23 11.2 3.0 8.7 6.0 0.1 2.8 2 1 1 3 3 3 0 Laminin Domain II FlaC_arch PF05377.6 KII87576.1 - 0.25 11.2 1.0 5.8 6.9 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 KII87576.1 - 0.29 10.6 6.6 1.4 8.4 0.3 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 KII87576.1 - 0.31 11.0 4.9 0.68 9.9 0.4 2.5 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.4 KII87576.1 - 0.46 10.4 5.6 0.13 12.2 0.5 1.9 1 1 0 2 2 2 0 Zinc finger-containing protein DUF641 PF04859.7 KII87576.1 - 0.64 9.7 3.8 1.2 8.9 0.2 2.6 2 2 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 KII87576.1 - 2 8.3 6.0 23 4.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 KII87576.1 - 3.5 7.5 7.4 22 4.9 2.0 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cortex-I_coil PF09304.5 KII87576.1 - 6.5 6.8 7.6 3 7.9 0.3 2.7 2 1 1 3 3 3 0 Cortexillin I, coiled coil Sec23_trunk PF04811.10 KII87577.1 - 2e-71 240.1 0.0 3.2e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KII87577.1 - 6.8e-22 76.8 0.1 1.3e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KII87577.1 - 5.9e-17 61.9 0.0 1.4e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KII87577.1 - 1.1e-16 60.1 6.7 1.9e-16 59.2 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KII87577.1 - 6.7e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 KII87577.1 - 1.6 8.7 9.1 0.042 13.7 0.6 2.2 2 0 0 2 2 2 0 WW domain Sec23_trunk PF04811.10 KII87578.1 - 1.1e-68 231.1 0.0 2e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KII87578.1 - 5.9e-23 80.2 0.0 1.3e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KII87578.1 - 4.8e-18 65.4 0.1 1.3e-17 64.0 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KII87578.1 - 1.7e-16 59.4 8.2 3.2e-16 58.5 5.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KII87578.1 - 3.4e-09 36.2 0.0 6.7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_S5_C PF03719.10 KII87579.1 - 3.9e-17 61.2 0.1 8.6e-17 60.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KII87579.1 - 7e-16 57.7 0.2 5.2e-15 54.9 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Methyltransf_19 PF04672.7 KII87579.1 - 0.027 13.7 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase PITH PF06201.8 KII87580.1 - 3.2e-38 130.8 0.0 4e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain ELYS PF13934.1 KII87581.1 - 5.4e-43 147.3 0.0 6.4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly MFS_1 PF07690.11 KII87582.1 - 1.1e-17 63.8 47.5 2.8e-10 39.4 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII87582.1 - 4.7e-05 21.9 18.6 4.7e-05 21.9 12.9 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein AAA PF00004.24 KII87583.1 - 3.1e-85 283.0 0.0 1e-41 142.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII87583.1 - 1.2e-13 50.9 0.0 1.5e-07 31.2 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KII87583.1 - 7.5e-13 48.0 0.0 0.00014 21.0 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KII87583.1 - 1.6e-12 47.8 0.1 3.3e-06 27.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 KII87583.1 - 3e-12 46.7 0.0 1.6e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KII87583.1 - 2.2e-09 37.5 0.0 0.0005 20.2 0.0 4.4 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KII87583.1 - 9.4e-09 34.9 2.8 0.06 12.7 0.1 4.2 2 2 2 4 4 4 3 AAA domain IstB_IS21 PF01695.12 KII87583.1 - 1.4e-08 34.3 0.0 0.0001 21.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KII87583.1 - 2.3e-08 33.6 1.2 3.5e-05 23.4 0.2 3.4 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 KII87583.1 - 4.3e-08 33.1 0.0 8.8e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KII87583.1 - 6.9e-08 31.6 0.0 0.0047 15.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KII87583.1 - 1.6e-07 31.2 0.0 0.0053 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KII87583.1 - 2.1e-07 30.2 0.0 0.0003 19.9 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KII87583.1 - 2.8e-07 31.3 0.0 1.8e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KII87583.1 - 7.5e-05 22.7 0.0 0.033 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII87583.1 - 9.9e-05 22.4 0.0 0.037 14.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DAP3 PF10236.4 KII87583.1 - 0.00018 20.5 0.0 0.00065 18.7 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Mg_chelatase PF01078.16 KII87583.1 - 0.00021 20.5 0.3 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KII87583.1 - 0.00036 20.2 0.0 0.098 12.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 KII87583.1 - 0.0013 18.8 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 KII87583.1 - 0.0039 16.4 0.1 0.25 10.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 KII87583.1 - 0.0045 16.4 0.0 0.92 8.9 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KII87583.1 - 0.0048 17.2 0.0 0.016 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KII87583.1 - 0.0058 16.2 0.0 0.9 9.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KII87583.1 - 0.0068 16.0 0.0 0.071 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KII87583.1 - 0.008 15.7 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KII87583.1 - 0.0095 15.5 0.0 0.031 13.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KII87583.1 - 0.01 15.5 0.0 8.9 5.9 0.0 3.7 2 2 2 4 4 4 0 Archaeal ATPase AAA_24 PF13479.1 KII87583.1 - 0.017 14.7 0.1 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KII87583.1 - 0.021 14.3 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 KII87583.1 - 0.025 13.4 0.0 0.096 11.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF433 PF04255.9 KII87583.1 - 0.029 13.7 0.0 0.079 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) ATP-synt_ab PF00006.20 KII87583.1 - 0.029 13.8 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Bac_DnaA PF00308.13 KII87583.1 - 0.038 13.6 0.0 0.5 9.9 0.0 2.5 3 0 0 3 3 3 0 Bacterial dnaA protein KaiC PF06745.8 KII87583.1 - 0.039 13.0 0.0 4 6.4 0.0 2.7 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 KII87583.1 - 0.05 13.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KII87583.1 - 0.098 11.5 0.0 5.5 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AFG1_ATPase PF03969.11 KII87583.1 - 0.19 10.4 0.0 0.88 8.3 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.8 KII87583.1 - 0.2 10.5 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KII87583.1 - 0.23 11.1 0.4 4.4 6.9 0.0 3.1 3 2 2 5 5 4 0 NTPase Rad17 PF03215.10 KII87583.1 - 0.26 9.9 0.0 3.5 6.2 0.0 2.3 2 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein Pkinase PF00069.20 KII87584.1 - 5.5e-53 179.7 0.0 6.5e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87584.1 - 7.5e-27 94.0 0.0 8.7e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII87584.1 - 0.00032 19.7 0.0 0.0015 17.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KII87584.1 - 0.0038 16.9 0.0 0.0089 15.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII87584.1 - 0.049 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KII87584.1 - 0.095 11.4 0.1 0.095 11.4 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF4551 PF15087.1 KII87586.1 - 3.4 5.9 10.3 4.1 5.6 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Transp_cyt_pur PF02133.10 KII87587.1 - 9.4e-143 475.9 43.0 1.1e-142 475.6 29.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 6PF2K PF01591.13 KII87588.1 - 5.1e-64 215.4 0.0 8.1e-64 214.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KII87588.1 - 5.7e-25 88.2 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KII87588.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KII87588.1 - 0.0046 16.1 0.0 0.0088 15.2 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KII87588.1 - 0.0064 17.3 0.5 0.025 15.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII87588.1 - 0.048 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin tRNA_lig_kinase PF08303.6 KII87588.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain RRM_1 PF00076.17 KII87589.1 - 7.4e-15 54.3 0.0 1.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87589.1 - 3.1e-10 39.8 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87589.1 - 2.7e-05 23.9 0.4 4.8e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KII87589.1 - 5.6e-05 23.4 0.1 0.00011 22.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF4316 PF14195.1 KII87589.1 - 0.13 12.3 0.1 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) MMR_HSR1 PF01926.18 KII87590.1 - 9.3e-11 41.7 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII87590.1 - 0.0066 15.7 0.3 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 KII87590.1 - 0.0088 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.8 KII87590.1 - 0.024 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.16 KII87590.1 - 0.025 13.8 0.0 0.075 12.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_17 PF13207.1 KII87590.1 - 0.043 14.6 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KII87590.1 - 0.044 12.5 0.2 0.092 11.5 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family AAA_16 PF13191.1 KII87590.1 - 0.055 13.4 0.4 0.1 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain DUF258 PF03193.11 KII87590.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KII87590.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KII87590.1 - 0.077 12.8 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 KII87590.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KII87590.1 - 0.2 11.1 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 KII87590.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Septin MFS_1 PF07690.11 KII87593.1 - 6.1e-20 71.2 51.0 4.7e-15 55.1 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.4 KII87593.1 - 0.016 15.4 2.2 0.15 12.2 0.3 2.8 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase RNA_pol_L_2 PF13656.1 KII87594.1 - 1.3e-23 82.1 0.0 2.3e-23 81.4 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KII87594.1 - 5.7e-11 41.3 0.0 8.9e-11 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 KII87594.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 2 0 0 2 2 2 0 Rio2, N-terminal Ribosomal_L18e PF00828.14 KII87595.1 - 6e-36 123.6 0.1 8.1e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 zf-C3HC4_3 PF13920.1 KII87596.1 - 5.7e-11 41.9 5.6 1.7e-09 37.1 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII87596.1 - 6e-06 26.1 5.6 9.1e-06 25.6 2.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII87596.1 - 0.00049 19.7 2.7 0.0012 18.4 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII87596.1 - 0.0021 17.8 7.3 0.045 13.5 5.2 2.5 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KII87596.1 - 0.0036 16.9 3.5 0.026 14.2 0.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain HLH PF00010.21 KII87598.1 - 3.1e-09 36.3 0.0 1.3e-08 34.3 0.0 2.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 KII87599.1 - 2.8e-67 226.6 0.0 4.9e-67 225.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87599.1 - 5.7e-32 110.8 0.0 1.1e-31 109.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII87599.1 - 4.4e-05 23.3 0.3 0.00023 20.9 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII87599.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPR PF01535.15 KII87600.1 - 7.4e-18 63.2 0.2 0.00095 18.9 0.0 5.7 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 KII87600.1 - 7.9e-15 53.8 4.6 0.0047 17.0 0.0 6.4 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 KII87600.1 - 2e-14 52.7 0.0 0.0022 17.4 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR_2 PF13041.1 KII87600.1 - 3.3e-14 52.5 0.0 0.015 15.2 0.0 5.2 4 1 1 5 5 5 3 PPR repeat family TPR_19 PF14559.1 KII87600.1 - 0.045 14.0 0.1 5.8 7.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII87600.1 - 0.13 12.9 4.2 21 6.1 0.0 4.6 2 1 1 3 3 3 0 Tetratricopeptide repeat SKG6 PF08693.5 KII87601.1 - 0.0004 19.6 1.4 0.0009 18.5 1.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 KII87601.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 KII87601.1 - 0.031 13.8 0.1 0.065 12.7 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KII87601.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.7 KII87601.1 - 0.14 12.0 1.6 0.27 11.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Syndecan PF01034.15 KII87601.1 - 0.15 11.7 0.1 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1517 PF07466.6 KII87601.1 - 2.2 7.1 7.7 2.4 7.0 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Gly-zipper_Omp PF13488.1 KII87601.1 - 4.4 7.0 13.7 15 5.2 9.5 2.0 1 1 0 1 1 1 0 Glycine zipper p450 PF00067.17 KII87602.1 - 4.6e-69 233.1 0.0 5.9e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VPS11_C PF12451.3 KII87602.1 - 0.013 15.2 0.2 0.028 14.2 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal SWIRM PF04433.12 KII87603.1 - 2.2e-35 120.6 0.0 6e-35 119.2 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 KII87603.1 - 5.5e-10 38.6 2.9 8.7e-10 37.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 KII87603.1 - 4.4e-09 36.3 0.0 8.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KII87603.1 - 4.7e-08 32.9 0.0 8.9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Benyvirus_P25 PF05744.6 KII87604.1 - 0.13 11.5 0.3 0.13 11.5 0.2 1.0 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Bac_export_3 PF01313.14 KII87605.1 - 0.9 9.2 4.9 0.14 11.8 0.4 1.9 2 0 0 2 2 2 0 Bacterial export proteins, family 3 ADH_N PF08240.7 KII87606.1 - 5.7e-30 103.2 1.3 9.6e-30 102.5 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII87606.1 - 1.1e-26 92.9 0.5 2e-26 92.0 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TOBE_2 PF08402.5 KII87606.1 - 0.1 12.6 0.1 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 TOBE domain ADH_zinc_N_2 PF13602.1 KII87606.1 - 0.11 13.4 0.4 0.19 12.6 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FMO-like PF00743.14 KII87607.1 - 1.6e-24 86.0 0.0 1.6e-13 49.7 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII87607.1 - 1e-13 51.8 0.0 2.8e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KII87607.1 - 1.8e-05 23.8 0.0 0.00014 20.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII87607.1 - 8.3e-05 22.5 0.0 0.023 14.5 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII87607.1 - 0.0019 17.9 0.3 5.7 6.6 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding ADH_zinc_N PF00107.21 KII87609.1 - 1.3e-29 102.3 0.2 2.3e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII87609.1 - 2.9e-28 97.8 1.7 4.6e-28 97.1 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII87609.1 - 0.017 15.9 0.5 0.033 15.0 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FYVE PF01363.16 KII87610.1 - 8.6e-08 31.9 7.8 8.6e-08 31.9 5.4 1.4 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KII87610.1 - 0.0022 17.8 12.1 0.0091 15.8 8.4 1.8 1 1 0 1 1 1 1 FYVE-type zinc finger DNA_RNApol_7kD PF03604.8 KII87610.1 - 0.028 13.8 1.9 0.028 13.8 1.3 2.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.17 KII87610.1 - 0.033 13.9 7.6 0.063 13.0 2.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.11 KII87610.1 - 0.17 11.7 12.9 6.7 6.6 6.8 3.1 2 1 1 3 3 3 0 AN1-like Zinc finger HypA PF01155.14 KII87610.1 - 0.67 9.6 7.5 0.31 10.7 3.6 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KII87610.1 - 2.3 8.0 12.6 0.42 10.4 2.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 KII87610.1 - 3.2 7.5 10.4 5 6.9 6.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zinc_ribbon_6 PF14599.1 KII87610.1 - 3.4 7.5 8.2 12 5.7 5.7 2.0 1 1 0 1 1 1 0 Zinc-ribbon Zn-ribbon_8 PF09723.5 KII87610.1 - 4.6 7.2 11.3 0.52 10.2 2.2 2.6 2 1 1 3 3 3 0 Zinc ribbon domain zf-C3HC4_4 PF15227.1 KII87610.1 - 6.3 6.7 10.7 1.3 8.9 1.2 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KII87611.1 - 2.6e-13 49.4 8.4 4e-13 48.8 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII87611.1 - 3.7e-08 33.2 9.0 5.8e-08 32.6 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII87611.1 - 1.3e-06 28.1 7.9 1.9e-06 27.5 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII87611.1 - 2.4e-05 23.8 9.3 3.8e-05 23.2 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 KII87611.1 - 0.0012 18.3 3.2 0.0019 17.6 2.2 1.3 1 0 0 1 1 1 1 P-11 zinc finger Prok-RING_4 PF14447.1 KII87611.1 - 0.0045 16.5 2.1 0.0091 15.5 1.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KII87611.1 - 0.017 14.8 7.5 0.03 14.0 5.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Ish1 PF10281.4 KII87611.1 - 0.043 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein U79_P34 PF03064.11 KII87611.1 - 0.064 12.7 5.4 0.1 12.1 3.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-RING_4 PF14570.1 KII87611.1 - 0.16 11.6 5.4 0.3 10.6 3.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KII87611.1 - 0.97 9.2 4.8 0.25 11.1 0.9 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger UPF0547 PF10571.4 KII87611.1 - 6.5 6.5 7.8 0.23 11.1 1.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Sec23_trunk PF04811.10 KII87612.1 - 5.6e-70 235.4 0.0 1e-69 234.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KII87612.1 - 7.1e-21 73.5 0.1 1.9e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KII87612.1 - 9.4e-18 64.5 0.1 2.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KII87612.1 - 9.8e-17 60.2 7.0 1.8e-16 59.4 4.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KII87612.1 - 6.4e-09 35.3 0.0 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 KII87612.1 - 9.8e-05 22.1 2.4 9.8e-05 22.1 1.6 2.4 2 0 0 2 2 2 1 WW domain DUF221 PF02714.10 KII87613.1 - 5.1e-101 337.7 13.4 7.6e-101 337.2 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KII87613.1 - 7.4e-38 129.5 4.6 7.4e-38 129.5 3.2 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KII87613.1 - 2e-15 57.0 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KII87613.1 - 4.9e-15 55.1 0.0 1.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein ATP-synt_10 PF05176.9 KII87614.1 - 9.3e-62 208.5 0.0 1.2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DUF155 PF02582.9 KII87615.1 - 1e-44 152.5 0.0 2.1e-44 151.5 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 PRiA4_ORF3 PF07929.6 KII87616.1 - 0.016 14.6 0.7 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein Peptidase_C78 PF07910.8 KII87616.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C78 TPT PF03151.11 KII87617.1 - 6.9e-22 77.7 11.6 6.9e-22 77.7 8.0 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KII87617.1 - 0.19 10.5 14.9 0.49 9.2 3.5 2.1 2 0 0 2 2 2 0 UAA transporter family DUF1118 PF06549.7 KII87617.1 - 0.94 9.6 5.5 0.49 10.5 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) LSM PF01423.17 KII87618.1 - 2e-15 56.0 0.3 2.4e-15 55.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 KII87618.1 - 0.086 12.3 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Repressor of phase-1 flagellin DUF563 PF04577.9 KII87619.1 - 2.2e-06 27.7 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.20 KII87620.1 - 3.3e-68 229.6 0.0 3.9e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87620.1 - 1.5e-27 96.3 0.0 2.2e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII87620.1 - 1.3e-06 27.5 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII87620.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KII87620.1 - 0.0024 16.9 0.2 0.005 15.9 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII87620.1 - 0.0048 16.6 0.2 0.13 11.9 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family TcdB_toxin_midN PF12256.3 KII87620.1 - 0.05 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region YukC PF10140.4 KII87620.1 - 0.063 11.8 0.0 0.086 11.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC NTF2 PF02136.15 KII87621.1 - 6.1e-26 91.1 0.0 9.5e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KII87621.1 - 3.7e-06 26.4 0.0 6.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87621.1 - 3.3e-05 23.6 0.0 6.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87621.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Het-C PF07217.6 KII87622.1 - 4.8e-226 751.6 0.0 5.9e-226 751.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DEAD PF00270.24 KII87625.1 - 8.6e-40 135.9 0.0 2.2e-38 131.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII87625.1 - 5e-25 87.1 0.0 1.1e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII87625.1 - 0.00062 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EXS PF03124.9 KII87627.1 - 2.3e-81 273.5 14.1 2.8e-81 273.2 9.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KII87627.1 - 3.8e-41 141.6 0.0 8.4e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 SPX domain RmlD_sub_bind PF04321.12 KII87630.1 - 2.7e-47 161.0 0.0 3.2e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KII87630.1 - 2.5e-20 72.9 0.0 3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KII87630.1 - 1.3e-06 27.5 0.0 0.00013 21.0 0.0 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KII87630.1 - 2.1e-06 27.9 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII87630.1 - 3.6e-06 26.0 0.0 0.0047 15.8 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 KII87630.1 - 0.041 13.7 0.1 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Vps16_C PF04840.7 KII87631.1 - 6e-86 288.2 0.1 8.4e-86 287.8 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 KII87631.1 - 1.7e-79 267.2 0.0 2.5e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region F-box-like PF12937.2 KII87632.1 - 8.2e-05 22.2 0.2 0.00023 20.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87632.1 - 0.0066 16.0 0.0 0.042 13.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain Tim44 PF04280.10 KII87633.1 - 0.00041 20.3 0.5 0.0011 18.9 0.3 1.8 1 1 0 1 1 1 1 Tim44-like domain CHCH PF06747.8 KII87634.1 - 0.0027 17.6 3.5 0.012 15.4 2.5 1.9 1 1 1 2 2 2 2 CHCH domain DUF2076 PF09849.4 KII87634.1 - 0.0049 16.9 4.4 0.0057 16.7 3.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) zinc-ribbons_6 PF07191.7 KII87634.1 - 0.23 11.2 2.0 0.4 10.4 1.4 1.4 1 0 0 1 1 1 0 zinc-ribbons Sec62 PF03839.11 KII87635.1 - 3.1e-47 160.8 4.6 2.3e-46 158.0 1.9 2.0 2 0 0 2 2 2 2 Translocation protein Sec62 DUF1517 PF07466.6 KII87635.1 - 0.43 9.5 2.2 0.44 9.4 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) TPR_12 PF13424.1 KII87636.1 - 4.3e-06 26.5 3.1 0.005 16.7 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII87636.1 - 0.0017 18.6 2.1 0.03 14.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII87636.1 - 0.0072 15.9 1.1 0.049 13.2 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KII87636.1 - 0.015 15.1 1.1 48 4.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII87636.1 - 0.043 14.4 3.0 0.95 10.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KII87636.1 - 2.5 8.7 0.0 2.5 8.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Terpene_synth_C PF03936.11 KII87637.1 - 7.7e-16 58.1 0.1 9.7e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.1 KII87637.1 - 0.05 13.4 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal UPF0113 PF03657.8 KII87637.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0113) MFS_1 PF07690.11 KII87638.1 - 5.6e-24 84.5 28.8 1.6e-19 69.8 4.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily HIG_1_N PF04588.8 KII87640.1 - 0.034 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Hypoxia induced protein conserved region AIG2 PF06094.7 KII87642.1 - 9.2e-15 54.9 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family WD40 PF00400.27 KII87643.1 - 6.2e-59 193.9 26.1 3.9e-12 45.5 0.1 12.9 14 0 0 14 14 14 9 WD domain, G-beta repeat Utp12 PF04003.7 KII87643.1 - 2.8e-24 85.1 0.0 4.3e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family IKI3 PF04762.7 KII87643.1 - 0.00014 19.8 0.0 1.2 6.8 0.0 3.4 2 1 0 3 3 3 2 IKI3 family Nup160 PF11715.3 KII87643.1 - 0.00044 18.5 0.3 0.11 10.5 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KII87643.1 - 0.001 17.4 0.4 6.5 4.9 0.0 3.8 4 0 0 4 4 4 2 Cytochrome D1 heme domain TFIIIC_delta PF12657.2 KII87643.1 - 0.037 13.7 0.1 32 4.1 0.0 4.0 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term RAB3GAP2_N PF14655.1 KII87643.1 - 0.053 12.5 0.0 0.83 8.5 0.0 2.8 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.7 KII87643.1 - 0.13 11.9 5.7 8 6.2 0.0 5.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat TruB_C PF09142.6 KII87643.1 - 6.6 6.4 6.8 38 4.0 0.0 4.8 8 0 0 8 8 8 0 tRNA Pseudouridine synthase II, C terminal Cnd1 PF12717.2 KII87644.1 - 1.8e-63 213.5 0.7 1.2e-58 197.8 0.1 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 KII87644.1 - 6.9e-50 169.0 0.0 6.9e-50 169.0 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 KII87644.1 - 1.6e-08 34.7 5.3 0.014 15.6 0.0 5.8 5 1 1 6 6 6 2 HEAT repeats Adaptin_N PF01602.15 KII87644.1 - 1.6e-06 26.7 3.2 0.0027 16.1 0.5 3.7 3 1 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.17 KII87644.1 - 0.0015 18.4 3.0 72 3.8 0.0 6.6 6 0 0 6 6 6 0 HEAT repeat YtzH PF14165.1 KII87644.1 - 0.0075 16.4 0.8 0.056 13.6 0.1 2.9 2 0 0 2 2 2 1 YtzH-like protein PIP5K PF01504.13 KII87645.1 - 5.6e-88 294.2 0.0 7.7e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SSP160 PF06933.6 KII87646.1 - 0.51 8.2 9.9 0.52 8.2 6.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ashwin PF15323.1 KII87646.1 - 1.3 8.9 7.0 1.7 8.6 4.9 1.2 1 0 0 1 1 1 0 Developmental protein KAR9 PF08580.5 KII87646.1 - 3.8 5.6 10.0 4.1 5.5 6.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_C50 PF03568.12 KII87647.1 - 2.7e-98 329.1 0.0 3.9e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KII87647.1 - 7.7e-05 22.5 12.6 0.39 10.6 0.1 5.7 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII87647.1 - 0.00097 18.8 6.7 4.2 7.5 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII87647.1 - 0.0045 16.5 0.4 6.2 6.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KII87647.1 - 0.0075 16.1 8.0 0.24 11.4 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII87647.1 - 0.24 11.0 8.1 8.8 6.0 0.0 4.3 3 2 0 4 4 4 0 TPR repeat Apyrase PF06079.6 KII87647.1 - 0.56 9.3 0.0 0.91 8.6 0.0 1.2 1 0 0 1 1 1 0 Apyrase Aldo_ket_red PF00248.16 KII87648.1 - 1.4e-47 161.9 0.0 1.9e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF965 PF06135.7 KII87648.1 - 0.085 12.9 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF965) CNH PF00780.17 KII87649.1 - 2.1e-12 47.0 0.0 3.7e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 CNH domain CBS PF00571.23 KII87650.1 - 4.2e-23 80.8 0.3 8.4e-06 25.4 0.1 4.3 4 0 0 4 4 4 4 CBS domain F-box PF00646.28 KII87651.1 - 0.00027 20.5 1.7 0.0006 19.4 1.2 1.6 1 0 0 1 1 1 1 F-box domain Ion_trans_2 PF07885.11 KII87652.1 - 7.7e-21 73.5 32.9 1.1e-12 47.5 7.0 3.4 3 0 0 3 3 3 2 Ion channel Glyco_transf_29 PF00777.13 KII87652.1 - 0.02 14.0 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 29 (sialyltransferase) UDP-g_GGTase PF06427.6 KII87653.1 - 7e-51 172.5 0.0 1.9e-50 171.1 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KII87653.1 - 2.6e-06 26.9 0.0 4.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mu-conotoxin PF05374.7 KII87655.1 - 0.44 10.3 10.2 1.8 8.4 2.1 3.3 3 0 0 3 3 3 0 Mu-Conotoxin Ldl_recept_a PF00057.13 KII87655.1 - 0.64 9.9 10.6 0.081 12.8 4.5 1.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A E1-E2_ATPase PF00122.15 KII87656.1 - 9.9e-58 194.8 0.2 9.9e-58 194.8 0.1 2.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KII87656.1 - 3e-24 86.6 0.5 5.5e-24 85.7 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII87656.1 - 1.3e-14 54.8 0.1 4e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KII87656.1 - 8.5e-12 44.3 0.0 2.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KII87656.1 - 8.5e-05 22.2 0.1 0.00057 19.5 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII87656.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit adh_short PF00106.20 KII87657.1 - 9.5e-18 64.6 0.0 1.2e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87657.1 - 1.4e-08 34.7 0.0 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87657.1 - 0.00017 21.2 0.0 0.00021 20.9 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KII87657.1 - 0.065 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC2_membrane PF01061.19 KII87658.1 - 1.2e-78 263.1 56.3 4.9e-42 143.4 13.2 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KII87658.1 - 1e-37 129.4 0.0 2.4e-17 63.5 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KII87658.1 - 2.3e-32 110.7 11.7 9.6e-29 99.0 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KII87658.1 - 7.5e-16 58.0 0.0 2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KII87658.1 - 2.1e-08 33.7 0.0 0.00038 19.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KII87658.1 - 4.4e-08 33.3 0.0 0.00049 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KII87658.1 - 1.3e-06 28.5 0.0 0.031 14.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KII87658.1 - 1.7e-06 27.3 0.0 8.9e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KII87658.1 - 9.4e-05 22.3 0.1 0.52 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII87658.1 - 0.00011 21.7 0.4 0.052 13.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KII87658.1 - 0.00019 21.1 0.2 0.12 11.9 0.1 3.0 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 KII87658.1 - 0.00046 20.4 0.0 0.46 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KII87658.1 - 0.0011 18.9 0.4 0.89 9.4 0.2 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KII87658.1 - 0.0016 18.3 0.0 1.5 8.8 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.2 KII87658.1 - 0.0016 17.5 25.5 0.0016 17.5 17.7 4.0 2 1 0 3 3 3 1 ABC-2 family transporter protein AAA_17 PF13207.1 KII87658.1 - 0.0017 19.2 0.0 0.94 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KII87658.1 - 0.002 17.5 2.0 0.086 12.2 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KII87658.1 - 0.0028 17.1 0.1 3.3 7.0 0.2 2.7 2 0 0 2 2 2 2 AAA-like domain Arch_ATPase PF01637.13 KII87658.1 - 0.0049 16.6 0.0 1.3 8.6 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KII87658.1 - 0.0077 15.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 KII87658.1 - 0.008 16.0 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 KII87658.1 - 0.0094 15.5 0.8 0.32 10.6 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KII87658.1 - 0.01 16.0 0.1 6.3 7.0 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KII87658.1 - 0.012 15.0 0.6 0.91 8.9 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KII87658.1 - 0.026 15.0 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 KII87658.1 - 0.035 14.0 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KII87658.1 - 0.048 13.4 2.9 1.5 8.6 0.4 2.7 2 0 0 2 2 2 0 Part of AAA domain Septin PF00735.13 KII87658.1 - 0.11 11.4 0.1 4.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.17 KII87658.1 - 0.15 12.2 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KII87658.1 - 0.17 12.1 0.1 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KII87658.1 - 0.54 9.2 0.0 3.6 6.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RabGAP-TBC PF00566.13 KII87659.1 - 5.7e-19 68.4 0.0 9.2e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_pol_N PF01194.12 KII87660.1 - 1e-30 105.5 0.4 1.2e-30 105.2 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KII87660.1 - 0.054 13.6 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF3522 PF12036.3 KII87661.1 - 0.13 12.0 2.3 0.45 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) DUF4131 PF13567.1 KII87661.1 - 0.32 10.3 9.1 0.69 9.3 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1275 PF06912.6 KII87661.1 - 0.34 10.0 4.4 2.3 7.3 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) BatA PF07584.6 KII87661.1 - 3.2 7.9 7.5 0.72 10.0 0.6 2.9 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal O-antigen_lig PF13425.1 KII87661.1 - 3.7 7.5 7.0 18 5.2 0.9 2.4 1 1 1 2 2 2 0 O-antigen ligase like membrane protein DUF805 PF05656.9 KII87661.1 - 4.7 7.0 8.3 7.4 6.4 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Amidase PF01425.16 KII87664.1 - 4.3e-104 348.8 0.0 5e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Amidase F-box-like PF12937.2 KII87665.1 - 1.2e-10 40.8 3.1 2.8e-10 39.7 2.1 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KII87665.1 - 0.38 10.4 5.0 3.3 7.4 0.8 2.6 2 1 0 2 2 2 0 F-box domain Pkinase PF00069.20 KII87666.1 - 6.1e-71 238.6 0.0 1e-70 237.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII87666.1 - 1e-41 142.7 0.0 1.5e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KII87666.1 - 1.3e-30 105.1 0.8 2e-19 69.3 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KII87666.1 - 3.6e-09 36.0 0.0 5.6e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 KII87666.1 - 0.023 14.2 0.1 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Kdo PF06293.9 KII87666.1 - 0.072 12.1 0.0 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII87666.1 - 0.23 11.1 2.9 0.53 9.9 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cys_Met_Meta_PP PF01053.15 KII87669.1 - 2.9e-24 85.0 0.0 4.8e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KII87669.1 - 0.00059 18.9 0.0 0.00093 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II F-box PF00646.28 KII87670.1 - 0.00068 19.2 0.3 0.0017 17.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain Apolipoprotein PF01442.13 KII87671.1 - 0.0067 15.9 3.1 0.016 14.6 1.8 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1481 PF07356.7 KII87671.1 - 0.012 15.0 1.4 0.02 14.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Baculo_PEP_C PF04513.7 KII87671.1 - 0.036 13.9 3.9 0.32 10.8 3.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.8 KII87671.1 - 0.4 9.5 4.2 0.52 9.1 2.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF3708 PF12501.3 KII87671.1 - 0.43 10.4 4.6 0.56 10.0 2.0 2.0 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF883 PF05957.8 KII87671.1 - 8.1 6.9 8.0 54 4.2 2.2 3.2 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) F-box PF00646.28 KII87672.1 - 0.0022 17.5 0.1 0.0055 16.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain PPTA PF01239.17 KII87673.1 - 4.5e-39 130.1 10.7 1.3e-07 30.6 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.6 KII87673.1 - 0.016 14.7 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) RRM_1 PF00076.17 KII87674.1 - 9.7e-14 50.7 0.0 1.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87674.1 - 1.8e-09 37.3 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87674.1 - 0.045 13.5 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C PF12355.3 KII87674.1 - 0.052 13.8 2.2 0.077 13.2 1.3 1.4 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal TC1 PF15063.1 KII87674.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Thyroid cancer protein 1 RNA_pol_3_Rpc31 PF11705.3 KII87675.1 - 9.3e-32 110.8 24.9 2.8e-31 109.2 17.2 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SPRR2 PF14820.1 KII87676.1 - 0.02 14.7 4.8 0.035 13.9 3.3 1.4 1 0 0 1 1 1 0 Small proline-rich 2 Vps39_2 PF10367.4 KII87677.1 - 1.9e-10 40.8 0.1 7.1e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KII87677.1 - 5.8e-08 32.7 0.2 1.3e-06 28.3 0.1 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 KII87677.1 - 5e-06 26.1 0.7 0.0018 17.9 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Glyco_transf_20 PF00982.16 KII87678.1 - 4.1e-152 506.9 0.0 6.3e-152 506.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KII87678.1 - 2e-74 249.4 0.0 3.6e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase RRM_1 PF00076.17 KII87679.1 - 1.7e-50 168.4 0.0 3.3e-16 58.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87679.1 - 1.3e-36 124.3 0.0 2e-12 46.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87679.1 - 4.5e-22 77.6 0.0 3e-06 26.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KII87679.1 - 0.00031 20.4 0.0 0.025 14.2 0.0 3.2 3 2 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 KII87679.1 - 0.0028 17.4 0.0 7.6 6.4 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif DUF3343 PF11823.3 KII87679.1 - 0.024 13.8 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) DUF791 PF05631.9 KII87680.1 - 1.4e-71 241.0 5.7 2.1e-71 240.4 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KII87680.1 - 6.7e-17 61.2 32.8 6.7e-17 61.2 22.7 2.1 1 1 2 3 3 3 2 Major Facilitator Superfamily PCMT PF01135.14 KII87681.1 - 2.1e-72 243.0 0.2 2.5e-72 242.8 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KII87681.1 - 1.9e-09 37.3 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII87681.1 - 5e-09 36.7 0.0 2.1e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII87681.1 - 3.8e-07 30.1 0.1 1.1e-06 28.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII87681.1 - 6.5e-06 25.9 0.0 9.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII87681.1 - 8.6e-06 26.1 0.0 2.4e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII87681.1 - 3.1e-05 23.2 0.0 4.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KII87681.1 - 0.00017 20.8 0.0 0.00039 19.6 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KII87681.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KII87681.1 - 0.00048 20.1 0.0 0.00068 19.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KII87681.1 - 0.0007 19.9 0.0 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KII87681.1 - 0.00098 18.6 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 KII87681.1 - 0.0017 17.7 0.1 0.0039 16.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.15 KII87681.1 - 0.0051 15.8 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 KII87681.1 - 0.0084 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Fibrillarin PF01269.12 KII87681.1 - 0.042 12.7 0.2 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Fibrillarin Methyltransf_3 PF01596.12 KII87681.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Mem_trans PF03547.13 KII87682.1 - 3.7e-38 130.8 7.9 2.5e-34 118.1 0.1 2.8 2 1 0 2 2 2 2 Membrane transport protein DUF3084 PF11283.3 KII87682.1 - 0.49 10.2 3.4 26 4.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) Ferritin_2 PF13668.1 KII87683.1 - 8e-44 148.9 0.3 1.1e-43 148.4 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Aldedh PF00171.17 KII87684.1 - 8.6e-85 284.7 0.0 1.1e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1156 PF06634.7 KII87684.1 - 0.053 13.2 1.5 0.14 11.9 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) FA_desaturase PF00487.19 KII87686.1 - 8.3e-25 87.6 26.3 1.5e-24 86.8 18.2 1.3 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KII87686.1 - 8.9e-06 25.7 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF802 PF05650.6 KII87690.1 - 3 8.0 7.3 0.22 11.6 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF802) MAM33 PF02330.11 KII87691.1 - 7.7e-39 133.5 0.2 8.9e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein APH PF01636.18 KII87695.1 - 7.7e-17 61.8 0.3 1.1e-16 61.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII87695.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KII87697.1 - 1.1e-16 61.3 0.1 1.7e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII87697.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-MYND PF01753.13 KII87698.1 - 1.3e-11 44.1 12.9 2.4e-11 43.3 9.0 1.4 1 0 0 1 1 1 1 MYND finger zf-RING_2 PF13639.1 KII87699.1 - 8.2e-14 51.1 5.1 1e-13 50.8 3.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII87699.1 - 3.8e-13 49.3 5.5 1.2e-12 47.7 3.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KII87699.1 - 1.2e-08 34.4 2.7 1.7e-08 33.9 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII87699.1 - 1.9e-08 33.8 2.0 2.7e-08 33.3 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII87699.1 - 2.9e-08 33.2 3.6 3.7e-08 32.9 2.5 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII87699.1 - 1.1e-07 31.8 3.7 1.5e-07 31.3 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII87699.1 - 1.9e-07 30.8 6.2 2.8e-06 27.0 4.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KII87699.1 - 2.9e-05 23.9 7.3 0.00062 19.6 5.0 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-P11 PF03854.9 KII87699.1 - 7.5e-05 22.1 1.5 0.00032 20.0 0.2 2.0 2 0 0 2 2 2 1 P-11 zinc finger RINGv PF12906.2 KII87699.1 - 0.0036 17.3 5.3 0.0071 16.3 3.7 1.5 1 1 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 KII87699.1 - 0.02 14.4 1.8 0.032 13.8 1.3 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KII87699.1 - 0.029 13.9 1.5 0.057 12.9 1.0 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 KII87699.1 - 0.043 13.8 2.6 0.043 13.8 1.8 1.5 2 0 0 2 2 1 0 RING-like domain zf-RING_6 PF14835.1 KII87699.1 - 0.07 12.9 1.4 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KII87699.1 - 0.11 12.1 2.1 0.26 11.0 1.4 1.7 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 KII87699.1 - 0.13 11.9 5.0 0.26 11.0 3.5 1.5 1 1 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.1 KII87699.1 - 0.15 11.5 4.7 0.3 10.6 2.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 KII87699.1 - 0.25 11.1 3.5 0.21 11.4 0.6 2.0 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 KII87699.1 - 0.38 10.5 4.2 1.4 8.7 0.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KII87699.1 - 6.7 6.5 8.1 2.3 7.9 2.8 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cnd3 PF12719.2 KII87700.1 - 2.1e-70 237.0 0.1 2.4e-69 233.5 0.0 2.8 2 2 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KII87700.1 - 4.7e-06 26.7 7.4 8.9e-06 25.9 0.2 4.2 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KII87700.1 - 0.001 18.9 7.0 1 9.6 0.1 5.5 6 0 0 6 6 6 1 HEAT repeat DUF605 PF04652.11 KII87700.1 - 0.11 11.8 7.4 0.69 9.2 2.9 2.3 2 0 0 2 2 2 0 Vta1 like HEAT_EZ PF13513.1 KII87700.1 - 0.41 11.1 8.7 0.35 11.4 0.5 4.6 3 1 2 5 5 5 0 HEAT-like repeat ORC6 PF05460.8 KII87700.1 - 2.4 7.1 12.3 1.3 8.0 5.0 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Homoserine_dh PF00742.14 KII87701.1 - 1.5e-44 151.8 0.0 2e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KII87701.1 - 3.6e-18 66.0 0.0 6.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Aldedh PF00171.17 KII87702.1 - 1.7e-87 293.6 0.0 2.1e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII87702.1 - 0.037 12.7 0.0 0.26 9.9 0.0 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) PNRC PF15365.1 KII87705.1 - 0.0042 17.0 0.8 0.0042 17.0 0.5 4.0 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator HECT_2 PF09814.4 KII87707.1 - 4.1e-37 127.7 0.0 6.5e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF676 PF05057.9 KII87708.1 - 4.3e-39 134.0 0.0 6.5e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KII87708.1 - 2.2e-06 27.3 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KII87708.1 - 0.0005 19.8 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KII87708.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein SPC25 PF06703.6 KII87709.1 - 1.1e-40 138.8 0.0 1.3e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) 4HBT PF03061.17 KII87709.1 - 0.042 13.9 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily 2-oxoacid_dh PF00198.18 KII87712.1 - 9.3e-81 270.4 0.1 1.3e-80 269.9 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KII87712.1 - 1.6e-19 69.2 0.5 3.1e-19 68.3 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KII87712.1 - 0.00022 20.5 1.7 0.0078 15.4 0.2 2.2 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KII87712.1 - 0.00053 19.5 0.0 0.072 12.7 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.14 KII87712.1 - 0.0087 15.7 0.5 0.019 14.6 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 KII87712.1 - 0.011 16.0 0.1 5 7.5 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Macoilin PF09726.4 KII87712.1 - 0.25 9.6 5.8 0.31 9.2 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3614 PF12267.3 KII87712.1 - 0.44 10.8 6.7 3.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) F-box-like PF12937.2 KII87713.1 - 0.0001 21.9 0.3 0.00034 20.2 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII87713.1 - 0.061 13.0 0.2 0.19 11.3 0.2 1.8 1 0 0 1 1 1 0 F-box domain WD40 PF00400.27 KII87714.1 - 2.6e-17 61.9 7.3 4.6e-06 26.3 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Metallophos PF00149.23 KII87715.1 - 1.4e-09 37.6 0.0 3.3e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 KII87716.1 - 3.1e-12 46.2 0.0 6.3e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII87716.1 - 1.3e-05 25.1 0.0 3.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Gp5_C PF06715.7 KII87717.1 - 0.48 10.4 3.5 1.1 9.3 2.3 1.8 1 1 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) Histone PF00125.19 KII87718.1 - 3.2e-26 91.2 0.0 4e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII87718.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KII87719.1 - 7.2e-21 74.1 0.1 1e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII87719.1 - 0.00017 21.6 1.4 0.0002 21.3 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KII87719.1 - 0.00092 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TerB-C PF15615.1 KII87720.1 - 1.1 9.5 5.1 1.6 8.9 3.5 1.4 1 1 0 1 1 1 0 TerB-C domain ERG2_Sigma1R PF04622.7 KII87721.1 - 2.3e-83 278.7 0.1 3e-83 278.3 0.1 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein GRAB PF10375.4 KII87722.1 - 5.6e-05 22.6 0.2 5.6e-05 22.6 0.2 1.7 2 0 0 2 2 2 1 GRIP-related Arf-binding domain LPP PF04728.8 KII87722.1 - 0.25 11.1 4.6 0.99 9.2 0.5 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Laminin_II PF06009.7 KII87722.1 - 2.6 7.7 12.5 7.5 6.3 3.7 2.5 2 0 0 2 2 2 0 Laminin Domain II AAA_13 PF13166.1 KII87722.1 - 5.1 5.4 15.5 0.76 8.1 1.0 2.1 1 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 KII87723.1 - 3.4e-31 106.6 0.0 5e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87723.1 - 2.3e-22 78.7 0.0 2.2e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87723.1 - 1.7e-07 30.9 0.0 0.0036 17.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 KII87723.1 - 0.012 15.6 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF2360 PF10152.4 KII87724.1 - 1.4 9.1 4.3 1.6 9.0 3.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 KII87724.1 - 2.3 7.5 6.4 2.4 7.4 4.4 1.1 1 0 0 1 1 1 0 Vta1 like Cu-oxidase PF00394.17 KII87726.1 - 3.4e-45 153.7 0.2 3e-41 140.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KII87726.1 - 2.3e-40 137.3 7.2 9.7e-39 132.0 0.2 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KII87726.1 - 2.2e-38 130.6 0.9 9.9e-36 122.0 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase ADH_zinc_N_2 PF13602.1 KII87727.1 - 6.1e-19 69.1 0.2 1.3e-18 68.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KII87727.1 - 6e-13 48.4 0.2 1.1e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KII87727.1 - 0.083 12.4 1.1 0.12 11.8 0.7 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KII87727.1 - 0.093 12.2 0.3 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Astacin PF01400.19 KII87730.1 - 0.15 11.4 0.4 0.27 10.6 0.3 1.5 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) UPF0104 PF03706.8 KII87731.1 - 0.03 13.6 0.2 0.72 9.0 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) DmsC PF04976.7 KII87731.1 - 0.068 12.4 0.5 0.074 12.3 0.4 1.1 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) DUF829 PF05705.9 KII87732.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) DUF1044 PF06296.7 KII87738.1 - 3.4 7.5 6.5 0.39 10.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1044) DUF832 PF05734.6 KII87743.1 - 0.14 11.3 0.5 0.21 10.7 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Pkinase PF00069.20 KII87745.1 - 4.1e-06 26.1 0.0 4.7e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII87745.1 - 0.00013 21.7 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII87745.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 KII87745.1 - 0.033 13.2 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Phage_integrase PF00589.17 KII87746.1 - 0.0032 17.1 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family RVT_3 PF13456.1 KII87747.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_thumb PF06817.9 KII87748.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase thumb domain Glyco_hydro_9 PF00759.14 KII87749.1 - 0.15 10.8 0.1 0.24 10.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Gag_p19 PF02228.11 KII87755.1 - 0.77 10.0 5.7 12 6.2 0.2 3.0 2 1 0 2 2 2 0 Major core protein p19 Pex16 PF08610.5 KII87758.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) zf-CCHC PF00098.18 KII87759.1 - 0.00021 21.0 5.2 0.00037 20.2 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Apc15p PF05841.6 KII87759.1 - 0.15 12.7 3.1 0.26 12.0 2.1 1.4 1 0 0 1 1 1 0 Apc15p protein SR-25 PF10500.4 KII87759.1 - 6 6.2 20.9 9.8 5.5 0.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein OPT PF03169.10 KII87761.1 - 3e-93 313.3 38.6 3.7e-93 313.0 26.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEC-1_N PF04625.8 KII87763.1 - 2 7.0 6.5 2.4 6.7 4.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Amino_oxidase PF01593.19 KII87764.1 - 2.7e-18 66.2 0.0 4.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII87764.1 - 5.7e-10 39.0 2.5 1.3e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII87764.1 - 1.1e-05 24.5 0.0 1.1e-05 24.5 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII87764.1 - 0.00032 21.0 1.9 0.54 10.7 0.0 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII87764.1 - 0.00094 19.2 2.2 0.3 11.1 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII87764.1 - 0.026 12.9 0.1 5.2 5.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KII87764.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 KII87764.1 - 0.24 9.7 0.1 2.3 6.4 0.0 1.9 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Glyco_hydro_61 PF03443.9 KII87765.1 - 1.1e-51 175.7 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 KII87765.1 - 0.063 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain CCER1 PF15482.1 KII87766.1 - 0.17 11.5 3.7 0.18 11.4 2.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 PWI PF01480.12 KII87767.1 - 5.9e-29 99.9 0.0 9.7e-29 99.3 0.0 1.3 1 0 0 1 1 1 1 PWI domain GRP PF07172.6 KII87767.1 - 0.085 13.3 8.0 0.13 12.7 5.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_S41 PF03572.13 KII87768.1 - 1e-05 25.0 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 p450 PF00067.17 KII87769.1 - 5.3e-74 249.4 0.0 1.1e-73 248.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Herpes_gE PF02480.11 KII87770.1 - 0.00032 19.0 0.2 0.00069 17.9 0.1 1.5 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 KII87770.1 - 0.0054 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Transmembrane protein 51 Protocadherin PF08374.6 KII87770.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 KII87770.1 - 0.014 15.7 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KII87770.1 - 0.014 14.9 1.6 0.029 13.9 1.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 KII87770.1 - 0.03 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family MscS_TM PF12794.2 KII87770.1 - 0.037 12.6 0.1 0.061 11.9 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CD34_antigen PF06365.7 KII87770.1 - 0.041 13.5 1.3 0.085 12.5 0.0 1.9 2 0 0 2 2 2 0 CD34/Podocalyxin family SID-1_RNA_chan PF13965.1 KII87770.1 - 0.045 11.9 0.0 0.057 11.5 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF912 PF06024.7 KII87770.1 - 0.051 13.6 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ly49 PF08391.5 KII87770.1 - 0.053 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Amnionless PF14828.1 KII87770.1 - 0.063 11.7 0.0 0.092 11.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless Plasmodium_Vir PF05795.6 KII87770.1 - 0.075 12.2 0.6 0.16 11.1 0.4 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF2207 PF09972.4 KII87770.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1180 PF06679.7 KII87770.1 - 4 7.2 8.0 0.28 11.0 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1180) ABC_tran PF00005.22 KII87771.1 - 2.6e-42 144.3 0.0 9e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII87771.1 - 7.1e-25 87.9 31.3 1.5e-14 54.0 4.0 4.0 4 1 0 4 4 4 2 ABC transporter transmembrane region AAA_25 PF13481.1 KII87771.1 - 1.3e-08 34.4 0.0 0.00069 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KII87771.1 - 0.00066 18.9 0.0 0.51 9.5 0.0 3.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KII87771.1 - 0.0009 18.7 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KII87771.1 - 0.0009 18.7 0.7 0.29 10.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KII87771.1 - 0.0026 18.1 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KII87771.1 - 0.0037 16.7 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 KII87771.1 - 0.0054 15.6 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein KaiC PF06745.8 KII87771.1 - 0.013 14.6 0.2 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF87 PF01935.12 KII87771.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_16 PF13191.1 KII87771.1 - 0.018 15.0 0.1 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KII87771.1 - 0.024 14.7 0.0 12 6.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KII87771.1 - 0.074 13.3 0.0 15 5.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 KII87771.1 - 0.13 12.7 0.2 24 5.4 0.1 2.7 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KII87771.1 - 0.58 9.0 0.1 7.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 KII87771.1 - 2.2 7.6 4.9 2.4 7.5 0.9 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DNA_primase_S PF01896.14 KII87772.1 - 9.9e-52 174.6 0.0 1.4e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit GST_N_2 PF13409.1 KII87773.1 - 4.1e-19 68.3 0.0 1e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII87773.1 - 2.9e-15 55.9 0.0 5.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII87773.1 - 1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII87773.1 - 3.4e-06 27.1 0.1 0.00015 21.8 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII87773.1 - 2.4e-05 24.7 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_N PF08240.7 KII87774.1 - 2e-29 101.5 0.5 3.9e-29 100.5 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII87774.1 - 5.9e-23 80.8 0.1 1.1e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII87774.1 - 2e-06 28.6 0.0 5.9e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KII87774.1 - 0.0029 17.1 0.1 0.0065 16.0 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 KII87774.1 - 0.0041 17.6 0.1 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KII87774.1 - 0.018 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KII87774.1 - 0.037 14.5 0.1 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KII87774.1 - 0.047 12.8 0.2 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.9 KII87774.1 - 0.054 12.8 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 KII87775.1 - 7.3e-17 61.7 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87775.1 - 1.3e-16 61.1 0.0 1.7e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87775.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.6 KII87775.1 - 0.044 13.2 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain Malic_M PF03949.10 KII87777.1 - 5.7e-82 275.1 0.0 7.4e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KII87777.1 - 1.9e-63 213.3 0.0 3.2e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain CcmD PF04995.9 KII87781.1 - 0.14 11.9 4.3 0.29 10.9 3.0 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SPOC PF07744.8 KII87781.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.4 1 1 0 1 1 1 0 SPOC domain EMP24_GP25L PF01105.19 KII87782.1 - 1.5e-38 132.3 0.0 1.6e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MR_MLE_C PF13378.1 KII87783.1 - 1.2e-31 108.9 0.1 2.5e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KII87783.1 - 2.4e-24 85.5 0.0 5.2e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KII87783.1 - 8e-11 42.3 0.0 2.4e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF1990 PF09348.5 KII87783.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Pkinase PF00069.20 KII87784.1 - 1.6e-05 24.1 0.1 3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII87784.1 - 0.0004 20.1 1.7 0.0014 18.4 1.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII87784.1 - 0.088 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UQ_con PF00179.21 KII87785.1 - 4.7e-52 175.1 0.0 5.2e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII87785.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KII87785.1 - 0.0014 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KII87785.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Ndufs5 PF10200.4 KII87787.1 - 0.00039 20.3 0.3 0.00054 19.9 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 KII87787.1 - 0.0015 18.2 1.1 0.0023 17.6 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KII87787.1 - 0.015 15.2 3.2 0.063 13.2 2.4 1.8 1 1 1 2 2 2 0 CHCH domain Pet191_N PF10203.4 KII87787.1 - 0.026 14.5 0.5 0.041 13.9 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 KII87787.1 - 0.098 12.7 2.0 0.23 11.5 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) PADR1 PF08063.7 KII87787.1 - 0.14 11.5 1.1 13 5.2 1.1 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain ubiquitin PF00240.18 KII87788.1 - 3.5e-16 58.3 0.0 5.7e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KII87788.1 - 3e-08 33.2 0.0 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KII87788.1 - 0.0018 18.4 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CLU_N PF15044.1 KII87788.1 - 0.0093 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term YukD PF08817.5 KII87788.1 - 0.058 13.9 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD G-patch PF01585.18 KII87789.1 - 1.6e-05 24.5 0.1 2.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.20 KII87790.1 - 7.9e-05 21.9 0.1 0.00013 21.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII87790.1 - 0.00013 21.8 0.0 0.00046 19.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII87790.1 - 0.026 13.5 0.1 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Nup96 PF12110.3 KII87791.1 - 6.2e-75 251.9 0.0 9.4e-75 251.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 eIF-3c_N PF05470.7 KII87791.1 - 0.44 8.5 5.1 0.61 8.1 3.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Daxx PF03344.10 KII87791.1 - 0.64 8.4 22.7 0.98 7.8 15.7 1.2 1 0 0 1 1 1 0 Daxx Family Rhabdo_ncap PF00945.13 KII87791.1 - 3.7 6.0 9.1 6 5.3 6.3 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nop14 PF04147.7 KII87791.1 - 6.4 4.5 33.2 9.6 3.9 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KII87791.1 - 7.4 4.4 21.5 12 3.7 14.9 1.3 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.20 KII87792.1 - 2.7e-13 50.1 0.2 4e-12 46.3 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87792.1 - 6.3e-06 26.1 0.0 0.00014 21.7 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87792.1 - 0.00044 19.9 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KII87792.1 - 0.0057 15.8 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 KII87793.1 - 3.1e-11 43.4 0.4 1.8e-10 40.9 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87793.1 - 2e-07 31.0 0.0 5.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87793.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.13 KII87793.1 - 0.051 13.2 0.3 0.074 12.7 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_FMN PF00724.15 KII87794.1 - 4.2e-35 121.3 0.0 6.6e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TFIIE_alpha PF02002.12 KII87796.1 - 2.1e-20 72.1 0.2 4.4e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 KII87796.1 - 1.4e-05 24.9 0.7 5.2e-05 23.1 0.5 2.1 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Zn_Tnp_IS1595 PF12760.2 KII87796.1 - 0.0079 15.9 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_4 PF14570.1 KII87796.1 - 0.068 12.7 2.8 0.41 10.2 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PhnA_Zn_Ribbon PF08274.7 KII87796.1 - 0.17 11.7 2.1 0.45 10.3 1.4 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Evr1_Alr PF04777.8 KII87796.1 - 0.2 11.5 1.3 0.43 10.5 0.7 1.7 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_4 PF13717.1 KII87796.1 - 0.6 9.8 3.0 3 7.6 2.1 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.21 KII87796.1 - 0.6 10.5 2.4 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_5 PF13719.1 KII87796.1 - 0.83 9.2 3.1 4.9 6.8 2.2 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Melibiase PF02065.13 KII87797.1 - 1.3e-15 56.9 0.1 1.3e-13 50.4 0.0 2.8 1 1 0 2 2 2 2 Melibiase WD40 PF00400.27 KII87798.1 - 5.6e-67 219.4 15.1 9.9e-10 37.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KII87798.1 - 1.4e-21 76.4 4.0 2.5e-21 75.6 2.8 1.3 1 0 0 1 1 1 1 Tup N-terminal eIF2A PF08662.6 KII87798.1 - 0.00068 19.3 0.0 7.2 6.2 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KII87798.1 - 0.0013 17.8 0.1 8.1 5.4 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF1777 PF08648.7 KII87798.1 - 0.0032 17.2 17.8 0.0059 16.3 12.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Cytochrom_D1 PF02239.11 KII87798.1 - 0.0057 14.9 0.3 0.09 11.0 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 KII87798.1 - 0.0087 15.7 1.7 25 4.6 0.0 5.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KII87798.1 - 0.01 14.0 0.6 0.39 8.7 0.1 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII87798.1 - 0.021 13.5 0.5 2.6 6.7 0.0 3.2 1 1 2 3 3 3 0 Nup133 N terminal like CENP-F_leu_zip PF10473.4 KII87798.1 - 0.022 14.6 0.8 0.035 13.9 0.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ORF6C PF10552.4 KII87798.1 - 0.051 13.3 0.5 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 ORF6C domain Mnd1 PF03962.10 KII87798.1 - 0.063 12.9 0.5 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 KII87798.1 - 0.069 13.0 1.4 0.13 12.1 1.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KII87798.1 - 0.083 11.5 0.2 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4071 PF13281.1 KII87798.1 - 0.47 9.2 1.3 2.5 6.8 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4071) IncA PF04156.9 KII87798.1 - 0.98 8.9 3.1 1.5 8.4 2.1 1.2 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 KII87799.1 - 2.6e-55 182.4 14.8 3.1e-11 42.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KII87799.1 - 9.3e-06 24.0 0.6 1.6 6.8 0.0 3.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KII87799.1 - 0.00042 18.7 0.5 0.28 9.4 0.0 2.8 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KII87799.1 - 0.016 13.9 0.1 4.5 5.9 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like NHL PF01436.16 KII87799.1 - 0.029 14.3 0.8 4.9 7.2 0.0 3.1 3 0 0 3 3 3 0 NHL repeat Peptidase_C13 PF01650.13 KII87800.1 - 3.3e-44 151.1 0.6 4.2e-44 150.7 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family HCNGP PF07818.8 KII87801.1 - 6.5e-24 83.7 0.1 9.5e-24 83.2 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein MR_MLE_C PF13378.1 KII87803.1 - 3.5e-17 62.3 0.0 7.9e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KII87803.1 - 1.1e-12 48.2 0.1 8.5e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KII87803.1 - 2.5e-08 33.9 0.0 5.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DnaJ PF00226.26 KII87804.1 - 1.5e-20 72.6 0.9 4.4e-20 71.1 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 KII87804.1 - 0.021 14.2 0.2 0.058 12.7 0.1 1.8 1 1 1 2 2 2 0 A repeated domain in UCH-protein eIF3_subunit PF08597.5 KII87804.1 - 0.1 12.1 17.8 0.24 10.9 12.3 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit VIT1 PF01988.14 KII87804.1 - 1 8.8 2.4 2.4 7.5 1.6 1.6 1 0 0 1 1 1 0 VIT family Borrelia_P83 PF05262.6 KII87804.1 - 2.4 6.3 12.1 3.3 5.8 8.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RP-C_C PF11800.3 KII87804.1 - 3.1 7.4 11.7 0.15 11.7 4.3 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF1649 PF07855.7 KII87805.1 - 1e-33 116.3 0.1 1.1e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DSPc PF00782.15 KII87806.1 - 3.7e-28 97.7 0.0 5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII87806.1 - 0.00069 19.0 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TraH_2 PF06871.6 KII87807.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 TraH_2 DUF1875 PF08961.5 KII87807.1 - 0.036 13.3 0.2 0.039 13.2 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) GCV_T PF01571.16 KII87807.1 - 0.092 12.0 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF2855 PF11017.3 KII87808.1 - 1.3e-68 231.4 0.0 1.5e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Mcp5_PH PF12814.2 KII87810.1 - 8.4e-43 145.1 0.0 1.6e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Myosin_tail_1 PF01576.14 KII87810.1 - 0.001 16.8 15.2 0.001 16.8 10.5 2.9 3 0 0 3 3 3 1 Myosin tail PH PF00169.24 KII87810.1 - 0.014 15.5 0.2 0.079 13.1 0.0 2.3 3 0 0 3 3 3 0 PH domain Sec23_trunk PF04811.10 KII87811.1 - 4.7e-53 180.0 0.0 8.1e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KII87811.1 - 3.7e-23 80.8 0.6 7.8e-23 79.8 0.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KII87811.1 - 1.9e-19 69.9 0.2 4.1e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KII87811.1 - 9e-15 53.9 5.3 1.8e-14 52.9 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KII87811.1 - 0.0016 18.0 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat CENP-F_leu_zip PF10473.4 KII87812.1 - 0.0012 18.7 54.9 0.14 12.0 1.0 5.5 2 1 4 6 6 6 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KII87812.1 - 0.0038 15.9 8.3 0.0038 15.9 5.7 4.3 2 1 2 4 4 4 3 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 KII87812.1 - 0.0071 16.1 6.4 0.0071 16.1 4.4 6.7 2 1 5 7 7 7 3 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KII87812.1 - 0.17 11.0 46.1 0.2 10.8 6.2 5.1 2 1 4 6 6 6 0 Reovirus sigma C capsid protein DDE_3 PF13358.1 KII87813.1 - 2.3e-08 33.9 0.0 1.1e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease IGR PF09597.5 KII87815.1 - 3.3e-14 52.5 0.0 4.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif APH PF01636.18 KII87816.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family FliX PF10768.4 KII87818.1 - 0.015 15.5 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 Class II flagellar assembly regulator DUF3400 PF11880.3 KII87818.1 - 0.032 13.4 0.2 0.071 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) GMC_oxred_N PF00732.14 KII87819.1 - 1.8e-73 247.3 0.0 2.3e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII87819.1 - 6.5e-38 130.2 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KII87819.1 - 4.5e-05 22.5 0.9 0.00014 20.9 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII87819.1 - 7.8e-05 22.6 0.1 0.00027 20.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII87819.1 - 0.00027 19.9 0.2 0.044 12.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KII87819.1 - 0.0022 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KII87819.1 - 0.0065 16.8 0.9 0.024 15.0 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII87819.1 - 0.034 14.0 0.1 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII87819.1 - 0.034 12.6 0.1 0.084 11.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 KII87819.1 - 0.081 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KII87819.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KII87819.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family PDEase_I PF00233.14 KII87820.1 - 6.4e-37 127.5 0.0 6.6e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KII87820.1 - 0.03 14.3 0.1 0.065 13.2 0.1 1.6 1 0 0 1 1 1 0 HD domain Methyltransf_16 PF10294.4 KII87822.1 - 2.7e-10 39.9 0.0 3.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF273 PF03314.9 KII87826.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Asp_protease_2 PF13650.1 KII87828.1 - 0.00018 21.9 0.0 0.00081 19.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KII87828.1 - 0.0058 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_1 PF03184.14 KII87829.1 - 5.9e-10 38.6 0.0 8.4e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BTB PF00651.26 KII87830.1 - 3.4e-05 23.8 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HTH_30 PF13556.1 KII87831.1 - 0.0031 17.0 0.7 0.0046 16.5 0.5 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Integrin_alpha PF00357.15 KII87831.1 - 0.13 12.0 0.5 0.32 10.8 0.3 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region HTH_8 PF02954.14 KII87831.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_20 PF12840.2 KII87831.1 - 0.14 11.9 0.5 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Cys_Met_Meta_PP PF01053.15 KII87833.1 - 1.5e-08 33.3 0.0 1.6e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Malate_synthase PF01274.17 KII87834.1 - 1.8e-75 253.9 0.0 2.3e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase RIO1 PF01163.17 KII87841.1 - 0.029 13.7 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Amidohydro_5 PF13594.1 KII87842.1 - 0.0013 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KII87842.1 - 0.013 15.5 0.5 0.13 12.2 0.3 2.3 1 1 0 1 1 1 0 Amidohydrolase Amidohydro_3 PF07969.6 KII87842.1 - 0.052 12.7 0.0 7.7 5.6 0.0 2.4 1 1 0 2 2 2 0 Amidohydrolase family MutS_V PF00488.16 KII87843.1 - 3.3e-76 255.7 0.0 5.1e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KII87843.1 - 1.4e-41 142.5 0.0 2.4e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KII87843.1 - 9.6e-34 115.8 0.1 2e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KII87843.1 - 1.1e-09 38.4 0.1 4.7e-09 36.4 0.1 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KII87843.1 - 4.7e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Glyco_hydro_16 PF00722.16 KII87844.1 - 2.1e-39 134.7 4.3 3.2e-39 134.1 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KII87844.1 - 0.33 10.9 16.5 1.1 9.3 11.4 1.9 1 1 0 1 1 1 0 Chitin recognition protein DUF667 PF05018.8 KII87845.1 - 6.7e-13 48.2 0.0 5.2e-06 25.8 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) Dioxygenase_C PF00775.16 KII87846.1 - 7.4e-55 185.0 0.0 1.1e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KII87846.1 - 1.2e-17 63.5 0.0 4.1e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus XPG_N PF00752.12 KII87847.1 - 3.8e-26 91.3 0.0 7.4e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KII87847.1 - 1.1e-25 89.4 0.0 2.6e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KII87847.1 - 3e-06 26.8 0.1 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KII87847.1 - 0.00018 21.6 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 KII87847.1 - 0.00093 19.3 0.0 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain TPR_2 PF07719.12 KII87847.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII87847.1 - 0.0043 16.5 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat HHH PF00633.18 KII87847.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_8 PF13181.1 KII87847.1 - 0.018 14.7 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH_2 PF12826.2 KII87847.1 - 0.021 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_21 PF09976.4 KII87847.1 - 0.04 13.8 0.2 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_75 PF07335.6 KII87847.1 - 0.096 12.5 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 Fungal chitosanase of glycosyl hydrolase group 75 zf-C2H2_4 PF13894.1 KII87849.1 - 7e-09 35.4 15.3 6.1e-05 23.0 0.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII87849.1 - 3.6e-07 30.1 14.1 4.8e-06 26.5 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KII87849.1 - 2.9e-06 27.2 9.3 0.00031 20.9 0.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KII87849.1 - 0.00017 21.6 3.8 0.00058 19.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII87849.1 - 0.00018 21.6 5.7 0.00028 20.9 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KII87849.1 - 0.0074 16.1 0.7 0.072 13.0 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 KII87849.1 - 0.14 11.9 4.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger Transpos_assoc PF13963.1 KII87849.1 - 0.24 11.3 1.9 0.48 10.4 1.3 1.4 1 0 0 1 1 1 0 Transposase-associated domain PIG-P PF08510.7 KII87850.1 - 2.5e-29 101.4 0.3 3e-29 101.1 0.2 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 KII87850.1 - 0.55 10.5 3.5 1.1 9.5 2.5 1.5 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 5-FTHF_cyc-lig PF01812.15 KII87851.1 - 1.3e-36 126.1 0.0 1.5e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rad51 PF08423.6 KII87852.1 - 2.6e-06 26.5 0.0 4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 KII87852.1 - 0.00022 20.4 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KII87852.1 - 0.0008 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KII87852.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KII87852.1 - 0.02 14.2 0.0 0.066 12.6 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein DnaB_C PF03796.10 KII87852.1 - 0.031 13.1 0.0 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_pol_A_CTD PF03118.10 KII87852.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA_19 PF13245.1 KII87852.1 - 0.098 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RRM_1 PF00076.17 KII87853.1 - 3.1e-21 74.7 0.0 3.1e-09 36.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87853.1 - 1.8e-19 69.3 0.0 5.4e-08 32.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87853.1 - 3.7e-19 68.4 0.0 9.4e-10 38.3 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 KII87854.1 - 1.6e-59 201.6 0.0 2.5e-58 197.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sec2p PF06428.6 KII87856.1 - 1.1e-12 47.6 10.9 1.1e-12 47.6 7.5 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Pheromone PF08015.6 KII87856.1 - 0.098 13.4 0.4 0.098 13.4 0.3 7.4 2 1 2 4 4 4 0 Fungal mating-type pheromone DivIC PF04977.10 KII87856.1 - 1.9 8.0 6.6 3.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator DFP PF04127.10 KII87857.1 - 6.1e-21 74.8 0.0 7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein GATase PF00117.23 KII87858.1 - 2.4e-09 36.9 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KII87858.1 - 0.05 13.0 0.2 0.35 10.2 0.1 2.3 1 1 0 1 1 1 0 Peptidase C26 Phosphorylase PF00343.15 KII87858.1 - 0.061 11.2 0.1 0.084 10.7 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase GATase_3 PF07685.9 KII87858.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SIS PF01380.17 KII87860.1 - 1.4e-60 202.5 0.1 4.3e-32 110.4 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KII87860.1 - 8e-21 74.1 0.0 5e-16 58.3 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KII87860.1 - 1.3e-17 64.0 0.0 3.4e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KII87860.1 - 8.8e-12 44.8 0.0 3.5e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KII87860.1 - 4.8e-07 28.7 0.0 8.2e-07 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KII87860.1 - 0.011 15.4 0.0 0.055 13.1 0.0 2.0 1 1 1 2 2 2 0 SIS domain DUF3129 PF11327.3 KII87861.1 - 1.7e-05 24.6 5.9 2.6e-05 24.1 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Gly_reductase PF09338.6 KII87861.1 - 0.08 11.1 0.5 0.081 11.0 0.3 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits GidB PF02527.10 KII87863.1 - 0.092 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G p450 PF00067.17 KII87864.1 - 1.8e-62 211.3 0.0 8.4e-62 209.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 BCLP PF12304.3 KII87865.1 - 0.088 12.2 4.7 0.49 9.7 0.3 2.3 2 0 0 2 2 2 0 Beta-casein like protein DUF35_N PF12172.3 KII87866.1 - 0.13 12.1 0.4 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF302 PF03625.9 KII87867.1 - 0.00068 19.1 0.0 0.00094 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 Formyl_trans_N PF00551.14 KII87868.1 - 2.4e-20 72.8 0.0 4.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KII87868.1 - 2.7e-08 33.7 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Stn1 PF10451.4 KII87869.1 - 1.4e-09 37.1 0.6 0.00036 19.4 0.1 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KII87869.1 - 3.2e-05 23.7 0.3 9.5e-05 22.1 0.2 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain TENA_THI-4 PF03070.11 KII87872.1 - 1.5e-11 44.4 0.1 6.7e-11 42.3 0.1 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family RRM_1 PF00076.17 KII87873.1 - 5.8e-11 41.8 0.0 8.5e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87873.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KII87873.1 - 6.2e-07 29.7 0.2 1.4e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KII87873.1 - 0.00097 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KII87874.1 - 1e-49 164.6 17.2 1.2e-07 31.3 0.5 9.7 10 0 0 10 10 10 8 WD domain, G-beta repeat IKI3 PF04762.7 KII87874.1 - 0.00084 17.2 0.0 0.56 7.9 0.0 2.6 3 0 0 3 3 3 2 IKI3 family Nbas_N PF15492.1 KII87874.1 - 0.0021 17.2 0.4 5 6.1 0.0 3.3 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 KII87874.1 - 0.0048 17.1 8.1 11 6.5 0.0 6.6 7 0 0 7 7 7 1 PQQ-like domain Nup160 PF11715.3 KII87874.1 - 0.01 13.9 2.8 0.022 12.8 1.0 2.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.7 KII87874.1 - 0.047 13.3 0.8 16 5.3 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Mad3_BUB1_I PF08311.7 KII87875.1 - 6.5e-28 97.0 0.2 9.4e-28 96.5 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ECH PF00378.15 KII87875.1 - 0.0096 15.0 0.2 0.024 13.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family CPSF_A PF03178.10 KII87876.1 - 5.8e-48 163.6 0.0 1.7e-47 162.1 0.0 1.8 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KII87876.1 - 1.2e-34 119.4 0.0 1.7e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Rad52_Rad22 PF04098.10 KII87877.1 - 3.4e-59 198.9 0.0 4e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MFS_1 PF07690.11 KII87878.1 - 1.8e-32 112.4 25.5 2.7e-32 111.8 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 KII87878.1 - 0.036 13.5 3.7 1.5 8.3 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF4131 PF13567.1 KII87878.1 - 0.29 10.5 3.6 6.1 6.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cupin_1 PF00190.17 KII87879.1 - 2.2e-29 101.7 0.0 1.4e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KII87879.1 - 4.3e-26 90.1 0.5 6.3e-12 44.8 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KII87879.1 - 4.2e-07 29.2 0.1 0.0024 17.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 KII87879.1 - 0.0022 17.6 0.0 0.0084 15.7 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 KII87879.1 - 0.0026 17.4 0.3 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain 3-HAO PF06052.7 KII87879.1 - 0.012 15.0 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 KII87879.1 - 0.014 14.6 0.0 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein GPI PF06560.6 KII87879.1 - 0.053 12.5 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_8 PF13621.1 KII87879.1 - 0.057 12.9 0.0 1.3 8.4 0.0 2.3 1 1 0 2 2 2 0 Cupin-like domain CENP-C_C PF11699.3 KII87879.1 - 0.071 13.0 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Mif2/CENP-C like RRM_1 PF00076.17 KII87881.1 - 4.2e-37 125.6 0.0 2.5e-19 68.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII87881.1 - 2.1e-23 82.0 0.0 1.6e-12 47.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII87881.1 - 4.7e-12 45.5 0.0 5.1e-07 29.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KII87881.1 - 1.1e-06 28.1 3.0 0.0012 18.4 0.0 3.3 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.8 KII87881.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KII87881.1 - 0.17 11.6 0.2 2 8.2 0.0 2.5 3 0 0 3 3 3 0 Limkain b1 Sterol_MT_C PF08498.5 KII87883.1 - 2.2e-24 85.1 0.2 3.3e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 KII87883.1 - 8.7e-20 70.8 0.0 1.3e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII87883.1 - 2.8e-18 66.1 0.0 6.8e-18 64.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 KII87883.1 - 3.5e-14 52.5 0.0 4.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KII87883.1 - 5e-13 49.6 0.0 4.4e-12 46.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII87883.1 - 6e-12 45.5 0.0 1.5e-11 44.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII87883.1 - 6.1e-12 45.8 0.1 1.7e-11 44.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII87883.1 - 2.2e-11 43.8 0.0 5.3e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII87883.1 - 6.1e-11 42.5 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII87883.1 - 5.2e-08 32.2 0.0 9.3e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KII87883.1 - 1.9e-05 24.0 0.0 3.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KII87883.1 - 3.7e-05 23.3 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 KII87883.1 - 0.00046 19.2 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_15 PF09445.5 KII87883.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.1 KII87883.1 - 0.0051 17.6 0.0 0.068 14.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Met_10 PF02475.11 KII87883.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 KII87883.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 KII87883.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KII87883.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.5 KII87883.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit WD40 PF00400.27 KII87886.1 - 5e-15 54.7 1.1 6.7e-08 32.1 0.0 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 KII87886.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF1699 PF08004.6 KII87888.1 - 0.052 13.0 0.2 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) F-box PF00646.28 KII87889.1 - 7.2e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII87889.1 - 0.0011 18.6 0.3 0.0053 16.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 KII87890.1 - 2.8e-07 30.1 0.1 0.0026 17.5 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Cas_CXXC_CXXC PF09706.5 KII87890.1 - 0.0074 16.4 1.0 0.014 15.5 0.7 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_CXXC_CXXC) DUF3248 PF11609.3 KII87890.1 - 0.011 15.4 0.1 0.19 11.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) Nucleoporin_N PF08801.6 KII87890.1 - 0.049 12.3 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Nup133 N terminal like Transposase_21 PF02992.9 KII87891.1 - 9e-07 28.2 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1593 PF07632.6 KII87892.1 - 0.08 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) TonB_2 PF13103.1 KII87893.1 - 0.11 12.5 12.7 5.8 7.0 0.0 5.2 5 0 0 5 5 5 0 TonB C terminal Cas_Csy3 PF09615.5 KII87893.1 - 0.69 8.9 34.4 0.65 9.0 2.8 5.0 1 1 4 5 5 5 0 CRISPR-associated protein (Cas_Csy3) DUF3135 PF11333.3 KII87893.1 - 3.1 8.0 17.8 25 5.1 0.1 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3135) ATG11 PF10377.4 KII87895.1 - 5.3e-33 113.6 0.8 1.1e-32 112.6 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 11 Prominin PF05478.6 KII87895.1 - 1.3 6.5 12.7 0.95 6.9 0.0 2.6 2 0 0 2 2 2 0 Prominin Sugar_tr PF00083.19 KII87896.1 - 9.6e-84 281.5 21.7 1.1e-83 281.3 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII87896.1 - 1.2e-25 89.9 57.9 4.8e-23 81.4 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII87896.1 - 1.1e-05 24.0 0.3 1.1e-05 24.0 0.2 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein PH_9 PF15410.1 KII87897.1 - 0.00016 21.8 0.0 0.0002 21.5 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KII87897.1 - 0.0075 16.4 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 PH domain Metallophos PF00149.23 KII87898.1 - 2.7e-44 150.9 0.1 3.4e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box PF00646.28 KII87899.1 - 0.0072 15.9 0.6 0.026 14.1 0.4 1.9 1 0 0 1 1 1 1 F-box domain DUF2156 PF09924.4 KII87900.1 - 1.3e-12 47.2 0.0 2.3e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) TcpQ PF10671.4 KII87900.1 - 0.092 12.6 0.0 8.5 6.3 0.0 3.0 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Gly_transf_sug PF04488.10 KII87901.1 - 2.5e-06 27.7 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KII87901.1 - 0.029 13.5 0.3 0.042 12.9 0.2 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein F-box-like PF12937.2 KII87902.1 - 0.0021 17.7 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII87903.1 - 0.00089 18.9 0.1 0.006 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII87903.1 - 0.011 15.3 0.1 0.081 12.6 0.0 2.6 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 KII87903.1 - 0.022 14.8 6.6 30 5.4 0.1 6.0 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KII87903.1 - 0.12 12.5 0.3 73 3.9 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 KII87903.1 - 0.48 10.2 6.1 2.2 8.1 0.0 4.3 7 0 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 KII87903.1 - 3.5 7.3 9.0 7.6 6.2 0.0 4.6 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF1769 PF08588.5 KII87904.1 - 3.8e-15 55.5 0.0 6.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Autophagy_Cterm PF10381.4 KII87904.1 - 0.019 14.0 0.1 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Apt1 PF10351.4 KII87904.1 - 0.24 10.2 1.8 0.27 10.0 1.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Corona_nucleoca PF00937.13 KII87904.1 - 5.2 5.9 13.4 7.6 5.3 9.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LRR_7 PF13504.1 KII87906.1 - 0.00063 19.5 2.2 27 5.5 0.3 5.4 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 KII87906.1 - 0.00083 19.0 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII87906.1 - 0.0012 18.4 1.0 2.1 8.0 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KII87906.1 - 0.02 14.5 0.0 0.065 12.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.1 KII87906.1 - 0.08 13.0 0.1 45 4.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 KII87906.1 - 0.17 11.6 0.8 9.8 6.0 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 KII87906.1 - 3.7 7.9 4.8 60 4.2 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat p450 PF00067.17 KII87907.1 - 3e-45 154.6 0.0 4e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4106 PF13388.1 KII87908.1 - 6.4 5.6 7.1 0.37 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) SMC_N PF02463.14 KII87909.1 - 8.9e-28 97.0 4.4 1.6e-27 96.1 3.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KII87909.1 - 3.4e-11 43.8 29.1 3.6e-08 33.9 20.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KII87909.1 - 2e-08 34.5 0.3 2.1e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII87909.1 - 3.4e-08 32.8 0.0 1.2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KII87909.1 - 0.0013 17.8 2.0 0.0044 16.1 1.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF2813 PF11398.3 KII87909.1 - 0.0049 16.0 0.0 0.0049 16.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_13 PF13166.1 KII87909.1 - 0.0061 15.0 25.3 0.14 10.6 14.0 2.3 1 1 1 2 2 2 2 AAA domain ABC_tran PF00005.22 KII87909.1 - 0.061 13.6 7.3 1.8 8.8 5.0 2.6 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KII87909.1 - 0.77 10.5 4.1 1.3 9.8 0.1 2.7 1 1 0 2 2 2 0 AAA domain DUF1342 PF07072.6 KII87909.1 - 0.79 9.3 9.2 0.34 10.5 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) AAA_16 PF13191.1 KII87909.1 - 1.6 8.6 6.8 2.8 7.8 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain DUF1664 PF07889.7 KII87909.1 - 1.8 8.3 8.5 1.3 8.7 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KII87909.1 - 2.4 6.7 18.6 6.5 5.3 12.5 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.4 KII87909.1 - 9.1 4.9 20.6 0.12 11.0 6.0 2.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DASH_Dam1 PF08653.5 KII87910.1 - 7.1e-14 51.3 0.0 1.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4519 PF15012.1 KII87910.1 - 0.048 13.5 0.8 0.083 12.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Cnd3 PF12719.2 KII87912.1 - 2.7e-73 246.5 2.9 6.4e-73 245.3 2.0 1.6 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KII87912.1 - 1.9e-08 34.4 7.7 0.00015 21.9 0.4 6.0 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 KII87912.1 - 1.4e-05 24.7 3.0 0.07 13.2 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat IFRD PF05004.8 KII87912.1 - 0.0059 15.7 0.9 0.19 10.7 0.0 3.1 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 KII87912.1 - 0.15 12.6 7.3 0.2 12.2 0.4 4.5 4 1 2 6 6 6 0 HEAT-like repeat Sec23_trunk PF04811.10 KII87913.1 - 5.7e-74 248.5 0.0 8.5e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KII87913.1 - 2.8e-35 119.8 0.3 5.6e-35 118.8 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KII87913.1 - 3.6e-30 104.3 0.3 7.6e-30 103.2 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KII87913.1 - 9.9e-17 60.2 6.7 1.9e-16 59.3 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KII87913.1 - 1e-13 50.7 0.0 5.1e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat OPT PF03169.10 KII87915.1 - 5e-145 484.3 53.7 5.7e-145 484.2 37.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NMD3 PF04981.8 KII87916.1 - 1.1e-73 247.2 0.4 1.4e-73 246.8 0.2 1.2 1 0 0 1 1 1 1 NMD3 family NinF PF05810.7 KII87916.1 - 0.019 14.7 1.4 0.076 12.8 0.5 2.3 2 0 0 2 2 2 0 NinF protein DZR PF12773.2 KII87916.1 - 0.021 14.6 5.1 0.11 12.3 2.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon Rpr2 PF04032.11 KII87916.1 - 0.036 13.9 1.1 0.72 9.7 0.1 2.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TT_ORF2 PF02957.10 KII87916.1 - 0.13 12.9 5.4 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 TT viral ORF2 zf-dskA_traR PF01258.12 KII87916.1 - 0.34 10.6 2.7 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_3 PF13920.1 KII87916.1 - 2 8.1 5.8 0.31 10.7 0.2 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Sdh5 PF03937.11 KII87920.1 - 1.7e-26 91.7 1.9 2.2e-26 91.3 1.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF1819 PF08849.6 KII87920.1 - 0.053 12.9 0.1 0.064 12.6 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) adh_short PF00106.20 KII87921.1 - 1.5e-27 96.5 4.8 1.9e-27 96.2 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII87921.1 - 1.4e-22 80.6 0.0 1.8e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII87921.1 - 5.3e-16 58.7 2.0 6.9e-16 58.4 1.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII87921.1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII87921.1 - 0.016 15.2 1.3 0.062 13.2 0.9 1.8 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 KII87921.1 - 0.016 13.8 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DEAD PF00270.24 KII87922.1 - 1.4e-41 141.8 0.2 2.1e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII87922.1 - 1.3e-23 82.6 0.1 3e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KII87922.1 - 0.036 13.1 0.2 0.08 11.9 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_3 PF13302.1 KII87923.1 - 4.7e-17 62.4 0.1 6.2e-15 55.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII87923.1 - 1.3e-11 44.3 0.4 2e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KII87923.1 - 1.3e-07 31.6 0.0 3.7e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII87923.1 - 1.8e-06 27.8 0.7 3.1e-05 23.9 0.5 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII87923.1 - 4e-05 23.7 0.0 6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA_bind_2 PF13725.1 KII87924.1 - 0.074 13.1 0.7 0.25 11.4 0.4 2.0 1 1 1 2 2 2 0 Possible tRNA binding domain Acetyltransf_3 PF13302.1 KII87928.1 - 4e-18 65.9 0.0 4.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII87928.1 - 4.8e-13 48.9 0.0 8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII87928.1 - 0.00019 21.5 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII87928.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 KII87928.1 - 0.0023 17.8 0.0 0.0047 16.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII87928.1 - 0.0025 17.8 0.0 0.0098 15.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII87929.1 - 1.2e-12 47.6 0.2 1.6e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KII87929.1 - 8.2e-12 45.4 0.1 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII87929.1 - 2e-06 27.4 0.1 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KII87929.1 - 2.1e-06 27.6 0.0 2.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII87929.1 - 6.6e-06 26.1 0.0 7.1e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII87929.1 - 3e-05 24.0 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII87930.1 - 1.4e-18 67.4 0.0 1.8e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII87930.1 - 1.2e-12 47.6 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KII87930.1 - 4.6e-05 23.3 0.0 0.00012 21.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII87930.1 - 0.0083 16.0 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII87930.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII87931.1 - 2.6e-09 37.4 0.0 3.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII87931.1 - 1.5e-08 34.5 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KII87931.1 - 0.00024 21.0 0.0 0.00027 20.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII87931.1 - 0.00088 19.1 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mitofilin PF09731.4 KII87932.1 - 0.097 11.3 14.0 0.11 11.1 9.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RNase_H2-Ydr279 PF09468.5 KII87932.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 KII87932.1 - 0.31 10.9 5.8 0.35 10.7 4.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 USP8_interact PF08941.5 KII87932.1 - 0.34 10.2 2.3 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 USP8 interacting APG6 PF04111.7 KII87932.1 - 6 5.8 8.0 7.4 5.5 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Acetyltransf_3 PF13302.1 KII87933.1 - 0.0024 18.0 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII87934.1 - 1.8e-20 73.5 0.0 2.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII87934.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KII87934.1 - 6.6e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII87934.1 - 2.5e-06 27.5 0.0 3.8e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII87934.1 - 0.079 13.0 0.0 7.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ycf9 PF01737.12 KII87935.1 - 0.11 11.9 0.2 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 YCF9 MAPEG PF01124.13 KII87936.1 - 3.6e-16 58.9 2.6 4.6e-16 58.6 1.8 1.1 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 KII87936.1 - 0.69 9.7 3.1 0.31 10.8 0.3 1.8 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family Transket_pyr PF02779.19 KII87937.1 - 1.3e-57 194.2 0.0 2e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KII87937.1 - 3.3e-33 114.7 0.0 5.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component HAD PF12710.2 KII87938.1 - 1.7e-16 60.9 0.1 2.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KII87938.1 - 4.2e-06 27.0 0.1 2.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KII87938.1 - 7.8e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 KII87938.1 - 0.00097 19.6 0.1 0.021 15.2 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KII87938.1 - 0.0048 16.0 0.0 0.0089 15.2 0.0 1.4 2 0 0 2 2 2 1 Putative Phosphatase SpoU_sub_bind PF08032.7 KII87938.1 - 0.021 15.0 0.0 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF3954 PF13128.1 KII87938.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) DEAD PF00270.24 KII87939.1 - 1e-18 67.4 0.0 1.8e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII87939.1 - 2.4e-07 30.7 0.0 1.7e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KII87939.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aldo_ket_red PF00248.16 KII87940.1 - 1.3e-52 178.4 0.0 1.5e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DEC-1_N PF04625.8 KII87941.1 - 0.15 10.7 0.9 0.29 9.7 0.6 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_S13_N PF08069.7 KII87942.1 - 2.4e-30 104.1 0.2 5.7e-30 102.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KII87942.1 - 4.9e-23 80.6 0.1 6.7e-23 80.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KII87942.1 - 0.016 14.9 0.1 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 'Paired box' domain Ribosomal_S6e PF01092.14 KII87943.1 - 5.9e-61 203.7 0.1 9.9e-61 203.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Auxin_canalis PF05703.6 KII87943.1 - 0.033 14.0 1.0 0.041 13.6 0.7 1.1 1 0 0 1 1 1 0 Auxin canalisation LRR19-TM PF15176.1 KII87944.1 - 0.0023 17.5 0.0 0.0082 15.8 0.0 1.9 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain DUF1191 PF06697.7 KII87944.1 - 0.0031 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4381 PF14316.1 KII87944.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1191 PF06697.7 KII87945.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 KII87945.1 - 0.015 13.6 0.1 0.021 13.0 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KII87945.1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vma12 PF11712.3 KII87946.1 - 0.016 14.9 1.0 0.016 14.9 0.7 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Herpes_LMP1 PF05297.6 KII87946.1 - 3.4 6.5 10.8 5.5 5.8 7.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) IBR PF01485.16 KII87947.1 - 1.3e-11 44.1 34.4 9.3e-07 28.6 5.4 3.4 3 0 0 3 3 3 3 IBR domain MFS_1 PF07690.11 KII87948.1 - 9.9e-40 136.3 25.5 9.9e-40 136.3 17.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII87948.1 - 2.9e-14 52.5 7.3 2.9e-14 52.5 5.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.6 KII87948.1 - 0.6 9.9 4.9 0.8 9.5 0.6 2.7 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Aldo_ket_red PF00248.16 KII87949.1 - 6.7e-73 244.9 0.0 7.6e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII87950.1 - 4.2e-72 242.3 0.0 4.8e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ChW PF07538.6 KII87950.1 - 0.17 11.4 0.5 0.32 10.5 0.3 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W HMG_box PF00505.14 KII87953.1 - 5e-12 45.9 0.5 8.9e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII87953.1 - 0.00083 19.6 0.1 0.0035 17.6 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain adh_short PF00106.20 KII87958.1 - 1e-09 38.5 0.0 1.5e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87958.1 - 5e-06 26.3 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Peptidase_C14 PF00656.17 KII87959.1 - 1.9e-26 93.2 0.0 3.8e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KII87959.1 - 0.006 16.4 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KII87960.1 - 8e-10 38.2 0.3 8.2e-08 31.8 0.2 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat Peptidase_C14 PF00656.17 KII87962.1 - 3.1e-25 89.3 0.0 4.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.27 KII87964.1 - 7e-28 95.4 11.4 6.5e-09 35.3 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_C14 PF00656.17 KII87965.1 - 2.1e-34 119.3 0.1 6.1e-34 117.8 0.1 1.7 1 1 0 1 1 1 1 Caspase domain DpnD-PcfM PF14207.1 KII87966.1 - 0.056 13.2 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 DpnD/PcfM-like protein adh_short PF00106.20 KII87967.1 - 2e-09 37.5 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87967.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII87968.1 - 2.9e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII87968.1 - 8.5e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain CASP_C PF08172.7 KII87969.1 - 0.045 12.7 2.8 0.072 12.1 2.0 1.3 1 0 0 1 1 1 0 CASP C terminal IncA PF04156.9 KII87969.1 - 1.4 8.4 4.1 2.2 7.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein tRNA-synt_1d PF00750.14 KII87970.1 - 9.8e-83 277.8 1.4 1.3e-82 277.4 0.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KII87970.1 - 3.1e-19 69.0 0.0 6.7e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain bZIP_2 PF07716.10 KII87971.1 - 2e-09 37.1 9.6 2e-09 37.1 6.7 2.7 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 KII87971.1 - 1.5e-08 34.4 18.5 3.9e-08 33.1 7.9 2.4 1 1 1 2 2 2 1 bZIP transcription factor Enkurin PF13864.1 KII87971.1 - 0.049 13.8 0.2 0.049 13.8 0.1 2.1 2 0 0 2 2 2 0 Calmodulin-binding bZIP_Maf PF03131.12 KII87971.1 - 0.11 12.7 13.5 0.27 11.5 9.0 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor CAF-1_p150 PF11600.3 KII87971.1 - 0.14 11.4 12.7 0.27 10.5 8.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 KII87971.1 - 0.2 10.5 7.8 16 4.2 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 KII87971.1 - 0.81 9.2 3.5 1.2 8.6 1.8 1.6 2 0 0 2 2 2 0 IncA protein DUF4551 PF15087.1 KII87971.1 - 0.87 7.8 4.0 1.1 7.4 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4355 PF14265.1 KII87971.1 - 1.1 9.2 12.4 32 4.4 8.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) HAP1_N PF04849.8 KII87971.1 - 1.3 7.8 8.0 3.3 6.5 5.5 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF904 PF06005.7 KII87971.1 - 1.8 8.9 5.5 0.22 11.8 0.8 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) Atg14 PF10186.4 KII87971.1 - 2.2 7.1 9.1 3.3 6.5 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_C PF12498.3 KII87971.1 - 2.8 9.1 6.9 18 6.6 0.4 2.5 2 0 0 2 2 2 0 Basic leucine-zipper C terminal DivIC PF04977.10 KII87971.1 - 3.1 7.3 6.9 12 5.4 0.9 2.4 2 1 0 2 2 2 0 Septum formation initiator CENP-R PF06729.7 KII87971.1 - 3.2 7.4 7.4 0.84 9.2 2.6 1.9 2 0 0 2 2 2 0 Kinetochore component, CENP-R ADIP PF11559.3 KII87971.1 - 6.8 6.5 11.9 4.7 7.0 7.2 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Dimer_Tnp_hAT PF05699.9 KII87972.1 - 2.8e-07 30.0 0.1 3.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Metallophos_2 PF12850.2 KII87973.1 - 1.6e-06 28.0 0.0 3.5e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KII87973.1 - 0.00019 20.8 0.0 0.00041 19.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF706 PF05153.10 KII87974.1 - 3.9e-128 426.0 1.0 4.9e-128 425.7 0.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) Aldo_ket_red PF00248.16 KII87975.1 - 3.3e-55 186.9 0.0 4.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF478 PF04334.7 KII87976.1 - 0.028 14.2 0.2 0.034 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF478) DivIC PF04977.10 KII87977.1 - 0.37 10.2 6.3 0.34 10.4 0.9 2.4 2 1 1 3 3 3 0 Septum formation initiator UPF0220 PF05255.6 KII87978.1 - 2.7e-53 179.6 0.0 3.6e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) GAGA_bind PF06217.7 KII87979.1 - 0.44 10.4 6.0 0.63 9.9 4.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family UPF0449 PF15136.1 KII87979.1 - 0.47 10.6 7.4 1.8 8.8 0.2 3.3 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 Aldo_ket_red PF00248.16 KII87981.1 - 2.2e-75 253.1 0.0 2.5e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KII87983.1 - 2.4e-48 164.6 54.0 6.5e-46 156.6 37.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII87983.1 - 1.7e-08 33.4 15.9 1.7e-08 33.4 11.0 3.3 3 1 1 4 4 4 2 Sugar (and other) transporter HMG_box PF00505.14 KII87986.1 - 3.4e-10 40.0 0.3 8.1e-10 38.8 0.2 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII87986.1 - 0.018 15.3 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain DUF2083 PF09856.4 KII87989.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) HMG_box PF00505.14 KII87993.1 - 4.1e-09 36.5 6.5 2.1e-08 34.2 4.5 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII87993.1 - 1.8e-07 31.3 3.1 3.9e-07 30.3 2.2 1.5 1 0 0 1 1 1 1 HMG-box domain Chorion_2 PF03964.10 KII87994.1 - 0.4 11.2 3.1 17 6.0 0.1 2.3 1 1 1 2 2 2 0 Chorion family 2 RCC1 PF00415.13 KII87996.1 - 8.9e-46 153.8 23.4 6.9e-09 35.7 0.2 7.1 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII87996.1 - 7.4e-31 105.0 47.5 1.5e-07 30.8 0.3 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SPASM PF13186.1 KII87996.1 - 0.042 14.1 0.0 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain AvrE PF11725.3 KII87996.1 - 0.081 9.9 0.0 0.11 9.5 0.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor Aldo_ket_red PF00248.16 KII87997.1 - 9.8e-73 244.4 0.0 1.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII87998.1 - 9.7e-73 244.4 0.1 1.1e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.1 KII87999.1 - 5.3e-80 269.0 33.5 6.6e-80 268.7 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII87999.1 - 6.3e-14 51.1 25.9 6.3e-14 51.1 17.9 1.3 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 KII88000.1 - 2.8e-14 52.9 0.0 3.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII88000.1 - 7.1e-07 29.3 0.0 8.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII88000.1 - 3.1e-06 26.8 0.1 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KII88000.1 - 3.6e-06 27.0 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII88000.1 - 0.0057 16.6 0.1 0.012 15.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII88000.1 - 0.0058 16.4 0.1 0.0071 16.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII88000.1 - 0.087 12.9 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAS_8 PF13188.1 KII88000.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain Acetyltransf_13 PF13880.1 KII88000.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF4563 PF15124.1 KII88002.1 - 0.07 12.7 1.7 2.1 7.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4563) Pro-kuma_activ PF09286.6 KII88003.1 - 6e-42 143.0 0.0 6.3e-41 139.7 0.0 2.3 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII88003.1 - 2.8e-12 46.3 2.1 2.8e-12 46.3 1.5 1.7 1 1 0 1 1 1 1 Subtilase family TraI PF07057.6 KII88003.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 DNA helicase TraI Cellulase PF00150.13 KII88004.1 - 5.9e-17 61.7 0.0 8.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KII88004.1 - 0.025 14.9 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Fungal_trans PF04082.13 KII88009.1 - 7.5e-17 61.0 0.1 1.5e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII88009.1 - 6.5e-06 25.9 11.1 1.1e-05 25.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCAT PF02450.10 KII88010.1 - 0.0006 18.8 0.0 0.00079 18.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase MIR PF02815.14 KII88012.1 - 1.5e-20 73.5 2.0 2.6e-17 62.9 0.3 2.6 1 1 1 2 2 2 2 MIR domain PGM_PMM_II PF02879.11 KII88012.1 - 1.9e-05 24.8 0.0 6.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF2842 PF11003.3 KII88014.1 - 7.2 6.5 7.1 4.6 7.1 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2842) PepSY_TM_2 PF13703.1 KII88015.1 - 0.75 10.0 4.4 0.61 10.3 0.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix ABC2_membrane_4 PF12730.2 KII88015.1 - 8.9 5.3 9.4 0.25 10.5 2.4 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Tetraspannin PF00335.15 KII88017.1 - 0.027 13.7 11.6 0.048 12.9 8.0 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.1 KII88017.1 - 5.1 6.4 9.2 1.2 8.5 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) KLRAQ PF10205.4 KII88019.1 - 0.00071 19.5 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein CorC_HlyC PF03471.12 KII88019.1 - 0.019 14.7 0.2 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Transporter associated domain GTP_EFTU_D2 PF03144.20 KII88019.1 - 0.5 10.5 2.7 23 5.1 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Tetraspannin PF00335.15 KII88021.1 - 2.9e-05 23.4 1.3 3.6e-05 23.1 0.9 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2975 PF11188.3 KII88021.1 - 2 8.1 9.1 4.2 7.0 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) adh_short PF00106.20 KII88022.1 - 1.2e-09 38.3 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII88022.1 - 4.4e-06 26.4 0.0 7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KII88023.1 - 1.7e-21 76.8 2.3 2.4e-20 73.1 1.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII88023.1 - 3e-10 40.0 0.4 9.1e-10 38.4 0.2 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KII88023.1 - 3e-07 30.1 0.3 5.9e-07 29.1 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII88023.1 - 4.5e-05 23.5 1.0 6.1e-05 23.0 0.7 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KII88023.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KII88023.1 - 0.0052 16.8 0.1 0.0088 16.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KII88023.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2807 PF10988.3 KII88023.1 - 0.12 11.8 0.3 0.21 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) adh_short PF00106.20 KII88024.1 - 1.2e-21 77.3 0.4 1.1e-20 74.2 0.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII88024.1 - 4.4e-09 36.2 0.1 7.4e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII88024.1 - 2.6e-07 30.3 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KII88024.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII88024.1 - 0.00069 19.6 0.2 0.0012 18.8 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KII88024.1 - 0.013 14.5 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KII88024.1 - 0.017 15.2 0.1 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KII88024.1 - 0.048 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LacI PF00356.16 KII88024.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HisKA PF00512.20 KII88025.1 - 0.73 9.8 3.4 2.3 8.2 1.5 2.5 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain DDE_Tnp_4 PF13359.1 KII88027.1 - 6.9e-19 67.9 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MBOAT_2 PF13813.1 KII88028.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Cauli_VI PF01693.11 KII88029.1 - 6.5e-24 83.6 2.0 1.3e-12 47.4 0.4 2.2 2 0 0 2 2 2 2 Caulimovirus viroplasmin KTSC PF13619.1 KII88029.1 - 0.12 12.0 0.0 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 KTSC domain Tet_JBP PF12851.2 KII88030.1 - 0.0068 15.7 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 KII88030.1 - 0.036 14.5 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-B_box PF00643.19 KII88031.1 - 0.0011 18.8 5.1 0.0022 17.8 3.5 1.5 1 0 0 1 1 1 1 B-box zinc finger Chol_subst-bind PF09129.6 KII88031.1 - 0.1 11.7 1.2 1.4 8.0 0.4 2.1 2 0 0 2 2 2 0 Cholesterol oxidase, substrate-binding DUF4218 PF13960.1 KII88032.1 - 0.051 13.0 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Nucleoplasmin PF03066.10 KII88032.1 - 2.3 7.6 6.0 4.1 6.9 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Tet_JBP PF12851.2 KII88037.1 - 0.00041 19.6 0.0 0.00063 19.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HALZ PF02183.13 KII88038.1 - 0.14 11.8 0.3 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper WD40 PF00400.27 KII88044.1 - 1.9e-33 113.1 22.8 1.3e-08 34.3 0.3 6.6 5 1 0 5 5 5 5 WD domain, G-beta repeat Hairy_orange PF07527.8 KII88044.1 - 0.017 14.8 0.7 6.8 6.5 0.1 3.0 2 0 0 2 2 2 0 Hairy Orange DUF1880 PF08976.6 KII88045.1 - 3.6 7.7 7.3 0.33 11.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1880) Chromo PF00385.19 KII88046.1 - 3.3e-08 33.0 0.1 8.6e-08 31.7 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KII88046.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MTBP_mid PF14919.1 KII88052.1 - 0.036 12.7 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding Peptidase_S8 PF00082.17 KII88053.1 - 0.066 12.3 2.9 0.17 10.9 2.0 1.7 1 1 0 1 1 1 0 Subtilase family Pro-kuma_activ PF09286.6 KII88055.1 - 6.7e-32 110.4 0.0 1e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Chlam_PMP PF02415.12 KII88058.1 - 5.1 7.5 5.9 9.9 6.6 4.1 1.6 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SAPS PF04499.10 KII88060.1 - 1.5 7.3 5.0 1.9 6.9 3.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pro-kuma_activ PF09286.6 KII88063.1 - 1.5e-40 138.5 0.0 2.3e-39 134.6 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII88063.1 - 5e-12 45.5 4.7 9.6e-12 44.6 3.3 1.4 1 0 0 1 1 1 1 Subtilase family NPR3 PF03666.8 KII88063.1 - 0.23 9.9 0.1 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mab-21 PF03281.9 KII88066.1 - 0.031 13.4 0.1 0.17 11.0 0.0 1.9 1 1 1 2 2 2 0 Mab-21 protein MFS_1 PF07690.11 KII88067.1 - 2.8e-40 138.1 71.4 4.5e-33 114.4 30.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII88067.1 - 1e-05 24.3 9.1 1e-05 24.3 6.3 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 KII88067.1 - 0.0098 15.6 4.9 2.3 8.0 0.7 3.2 3 0 0 3 3 3 2 MFS_1 like family Glyco_hydro_2 PF00703.16 KII88068.1 - 0.00076 19.9 0.1 0.0025 18.2 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KII88068.1 - 0.13 11.1 0.1 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.11 KII88069.1 - 1.1e-13 50.6 65.1 3e-13 49.2 41.0 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 KII88071.1 - 0.0016 18.2 9.5 0.0016 18.2 6.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII88071.1 - 0.0055 16.3 7.6 0.0055 16.3 5.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII88071.1 - 0.0056 16.6 8.9 0.0056 16.6 6.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII88071.1 - 0.012 15.3 8.8 0.012 15.3 6.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 KII88071.1 - 0.032 12.5 15.6 0.042 12.0 10.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-NADH-PPase PF09297.6 KII88071.1 - 0.075 12.5 0.3 0.075 12.5 0.2 2.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-RING_5 PF14634.1 KII88071.1 - 0.28 10.9 16.7 0.056 13.1 5.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII88071.1 - 0.88 9.3 6.8 2.5 7.8 4.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 KII88071.1 - 3.4 7.5 11.1 8.8 6.2 0.5 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 KII88071.1 - 6.3 6.4 10.3 1.2 8.8 3.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KII88072.1 - 4.8e-13 48.7 42.9 1.5e-06 27.9 4.0 4.5 4 0 0 4 4 4 4 IBR domain zf-RING_2 PF13639.1 KII88072.1 - 1e-05 25.2 5.2 1e-05 25.2 3.6 4.8 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KII88072.1 - 0.00024 20.6 2.1 0.00024 20.6 1.5 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII88072.1 - 0.0016 18.4 6.1 0.0016 18.4 4.2 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII88072.1 - 0.0043 16.7 2.8 0.0043 16.7 2.0 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.19 KII88072.1 - 0.024 14.5 3.6 0.024 14.5 2.5 4.8 4 1 0 4 4 4 0 B-box zinc finger DNA_pol_A PF00476.15 KII88075.1 - 3.5e-92 308.9 0.0 5e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A Nup_retrotrp_bd PF10599.4 KII88076.1 - 2.9 8.5 8.3 18 6.0 0.2 2.5 1 1 1 2 2 2 0 Retro-transposon transporting motif AA_permease PF00324.16 KII88077.1 - 4e-110 368.4 32.4 4.5e-110 368.2 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII88077.1 - 2.1e-18 66.0 38.0 2.9e-18 65.6 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KII88077.1 - 5 6.8 15.6 0.046 13.4 2.7 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) F-box-like PF12937.2 KII88078.1 - 6.3e-10 38.6 0.2 2.2e-09 36.8 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII88079.1 - 7e-11 41.6 0.3 1.7e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88079.1 - 0.43 10.2 2.6 0.66 9.7 0.6 2.2 2 0 0 2 2 2 0 F-box domain SQS_PSY PF00494.14 KII88080.1 - 1.5e-12 47.4 0.5 3.8e-11 42.8 0.4 2.1 1 1 0 1 1 1 1 Squalene/phytoene synthase DUF3733 PF12534.3 KII88080.1 - 1.1 8.5 2.9 2.6 7.3 2.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 SQS_PSY PF00494.14 KII88081.1 - 3.1e-41 141.4 0.1 4.6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Dus PF01207.12 KII88082.1 - 2e-64 217.4 0.0 2.5e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 KII88082.1 - 6.9e-05 22.5 0.0 0.012 15.2 0.0 2.2 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.10 KII88082.1 - 0.00019 20.7 0.1 0.0036 16.5 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 KII88082.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KII88082.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KII88082.1 - 0.04 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.16 KII88082.1 - 0.076 11.9 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase AP_endonuc_2 PF01261.19 KII88082.1 - 0.084 12.1 0.2 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel IMPDH PF00478.20 KII88082.1 - 0.1 11.4 0.1 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF1272 PF06906.6 KII88085.1 - 9.1 6.2 8.3 0.22 11.3 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Zn_clus PF00172.13 KII88086.1 - 4.5e-05 23.2 11.1 7.3e-05 22.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.16 KII88087.1 - 6.5e-79 265.0 0.1 7.6e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family DASH_Dad3 PF08656.5 KII88089.1 - 2.5e-20 71.9 0.0 2.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 CBF PF03914.12 KII88089.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 2 0 0 2 2 2 0 CBF/Mak21 family WD40 PF00400.27 KII88090.1 - 2.3e-23 81.1 8.7 1.3e-08 34.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 KII88090.1 - 0.0001 21.6 0.1 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 KII88090.1 - 0.0038 15.8 0.8 0.056 12.0 0.1 2.6 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 KII88090.1 - 0.01 15.5 0.1 0.97 9.1 0.0 3.0 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A BTB PF00651.26 KII88091.1 - 0.13 12.2 0.0 8.9 6.3 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Pkinase PF00069.20 KII88092.1 - 7.7e-53 179.2 0.0 9.5e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88092.1 - 2e-27 95.8 0.0 2.6e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII88092.1 - 5.7e-06 25.5 0.0 8.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII88092.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII88092.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.22 KII88095.1 - 4.9e-56 186.4 3.6 7.8e-22 76.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Formyl_trans_N PF00551.14 KII88096.1 - 1.6e-36 125.5 0.0 1.8e-17 63.4 0.1 2.0 2 0 0 2 2 2 2 Formyl transferase Glyco_hydro_15 PF00723.16 KII88097.1 - 3e-49 167.8 0.0 1.5e-48 165.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.20 KII88098.1 - 3.6e-28 98.4 0.0 8.6e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88098.1 - 1.7e-18 66.6 1.0 4.7e-18 65.1 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 KII88098.1 - 0.011 14.6 1.4 0.038 12.9 0.0 2.4 3 0 0 3 3 3 0 Kinase-like AAA_13 PF13166.1 KII88098.1 - 5.6 5.2 12.5 7.8 4.8 8.7 1.1 1 0 0 1 1 1 0 AAA domain DUF1602 PF07673.9 KII88105.1 - 4.5 6.8 10.5 7.2 6.1 0.9 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1602) Ins_P5_2-kin PF06090.7 KII88112.1 - 8.2e-49 166.3 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase F-box-like PF12937.2 KII88112.1 - 2.9e-07 30.1 1.7 8.5e-07 28.6 1.2 1.9 1 0 0 1 1 1 1 F-box-like Ins_P5_2-kin PF06090.7 KII88113.1 - 1.8e-53 181.6 0.0 3.8e-53 180.5 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase F-box-like PF12937.2 KII88113.1 - 1.1e-06 28.2 2.3 4e-06 26.4 1.6 2.1 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.16 KII88115.1 - 6.2e-27 94.4 0.0 8.1e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Ins_P5_2-kin PF06090.7 KII88117.1 - 1e-54 185.7 0.0 1.8e-54 184.8 0.0 1.4 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase F-box-like PF12937.2 KII88117.1 - 4.1e-06 26.4 0.6 1.1e-05 25.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88117.1 - 0.0067 16.0 0.4 0.021 14.4 0.3 2.0 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII88118.1 - 3.1e-07 30.0 0.0 1.3e-06 27.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like Tim54 PF11711.3 KII88120.1 - 4.1e-72 242.8 0.0 1e-71 241.5 0.0 1.7 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Epimerase_Csub PF13950.1 KII88120.1 - 0.14 12.1 0.7 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit Sec63 PF02889.11 KII88121.1 - 6e-45 153.8 0.0 9.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KII88121.1 - 4.4e-23 81.6 0.0 8.9e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII88121.1 - 5.7e-10 39.3 0.4 5.4e-09 36.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KII88121.1 - 8.6e-07 28.7 0.0 2.9e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TAF4 PF05236.9 KII88121.1 - 0.0019 17.5 3.7 0.0046 16.2 2.5 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family T2SE PF00437.15 KII88121.1 - 0.026 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KII88121.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KII88121.1 - 0.056 13.5 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain CKS PF01111.14 KII88122.1 - 7.3e-36 121.8 0.1 8.9e-36 121.5 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16 PF00675.15 KII88123.1 - 5.2e-39 133.3 0.2 2.7e-38 131.0 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KII88123.1 - 2.2e-21 76.3 0.0 3e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Histone_HNS PF00816.16 KII88124.1 - 0.27 11.7 3.3 10 6.7 0.2 2.5 2 0 0 2 2 2 0 H-NS histone family CwfJ_C_1 PF04677.10 KII88125.1 - 7.3e-29 99.9 0.0 1.2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KII88125.1 - 5e-20 71.8 0.0 8.4e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 KII88125.1 - 1.3e-12 46.9 17.2 1.5e-05 24.3 1.5 3.6 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 KII88125.1 - 6.1e-07 29.0 13.9 0.0033 17.2 0.1 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 KII88125.1 - 0.12 12.1 4.8 5.3 6.8 0.1 3.4 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII88125.1 - 0.56 9.9 12.5 1.3 8.7 0.3 3.5 3 0 0 3 3 3 0 Zinc knuckle NIF PF03031.13 KII88126.1 - 1.1e-18 67.4 0.0 7.2e-18 64.7 0.0 2.1 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 KII88126.1 - 5.3e-07 28.9 0.0 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Acid_phosphat_B PF03767.9 KII88126.1 - 0.068 12.5 0.1 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) COesterase PF00135.23 KII88127.1 - 6.8e-62 209.8 0.0 9.2e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII88127.1 - 1.6e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KII88127.1 - 0.11 11.3 0.1 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme COesterase PF00135.23 KII88128.1 - 2e-105 353.5 0.0 3e-105 352.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII88128.1 - 1.4e-06 28.0 0.6 1.8e-05 24.3 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII88128.1 - 0.042 13.6 0.3 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family CENP-C_C PF11699.3 KII88129.1 - 1.3e-26 92.3 0.1 2.3e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KII88129.1 - 6.2e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KII88129.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Aha1_N PF09229.6 KII88130.1 - 6.7e-25 87.4 0.0 1.1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KII88130.1 - 9.8e-16 57.9 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 KII88130.1 - 7.6e-05 22.8 2.0 0.00046 20.3 0.1 2.4 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport DUF3235 PF11574.3 KII88130.1 - 2.3 8.5 8.9 0.53 10.5 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Septin PF00735.13 KII88131.1 - 1e-114 382.3 1.4 1.2e-114 382.0 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KII88131.1 - 3.6e-08 33.3 0.0 1.1e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KII88131.1 - 5.8e-07 28.8 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KII88131.1 - 5.5e-06 25.6 0.0 9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KII88131.1 - 2.8e-05 23.6 0.3 0.00042 19.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KII88131.1 - 4.7e-05 23.2 0.6 0.11 12.3 0.2 2.4 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 KII88131.1 - 0.00027 20.4 0.0 0.00053 19.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 KII88131.1 - 0.0007 18.7 0.2 0.0025 17.0 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 KII88131.1 - 0.00082 19.6 0.4 0.0014 18.8 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 KII88131.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 KII88131.1 - 0.0013 17.6 0.1 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 KII88131.1 - 0.0039 16.0 0.0 0.0079 15.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain IIGP PF05049.8 KII88131.1 - 0.011 14.5 0.4 0.086 11.6 0.0 2.2 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 KII88131.1 - 0.011 16.2 0.1 0.034 14.6 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 KII88131.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KII88131.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KII88131.1 - 0.016 15.1 0.4 0.14 12.0 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KII88131.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KII88131.1 - 0.028 14.7 0.1 0.064 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 KII88131.1 - 0.028 13.7 0.3 0.2 11.0 0.0 2.3 2 1 0 2 2 2 0 Ras family DUF815 PF05673.8 KII88131.1 - 0.083 11.8 0.1 0.28 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 KII88131.1 - 0.083 12.6 0.4 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KII88131.1 - 0.1 13.4 1.5 2.7 8.8 0.2 2.5 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KII88131.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GST_N PF02798.15 KII88133.1 - 3.6e-12 46.2 0.0 6.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII88133.1 - 8.2e-12 44.9 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII88133.1 - 2.5e-11 43.6 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII88133.1 - 2.3e-10 40.3 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII88133.1 - 4e-09 36.2 0.1 1.1e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII88133.1 - 2.4e-05 24.7 0.1 5.7e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KII88133.1 - 0.12 12.7 0.0 0.74 10.2 0.0 2.0 1 1 0 1 1 1 0 MetRS-N binding domain CENP-C_C PF11699.3 KII88134.1 - 6.8e-28 96.4 0.0 9.9e-28 95.9 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KII88134.1 - 3.5e-05 23.2 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HgmA PF04209.8 KII88134.1 - 0.012 13.9 0.0 0.017 13.5 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Microvir_J PF04726.8 KII88134.1 - 0.015 15.2 1.4 0.03 14.2 1.0 1.5 1 0 0 1 1 1 0 Microvirus J protein AraC_binding PF02311.14 KII88134.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.2 KII88134.1 - 0.076 12.6 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Cupin EutQ PF06249.7 KII88134.1 - 0.086 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ COesterase PF00135.23 KII88136.1 - 1.4e-96 324.3 0.0 2.4e-96 323.5 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII88136.1 - 6.6e-08 32.3 1.1 1.1e-07 31.6 0.8 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII88136.1 - 1.8e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII88136.1 - 0.013 15.2 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 KII88136.1 - 0.091 12.1 0.4 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 Putative esterase Aminotran_5 PF00266.14 KII88138.1 - 5.4e-89 298.5 0.0 2.2e-78 263.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KII88138.1 - 0.00031 19.8 0.1 0.0028 16.7 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KII88138.1 - 0.012 13.9 0.2 0.018 13.3 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_6 PF01341.12 KII88139.1 - 5.8e-110 367.4 3.7 7.1e-110 367.1 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KII88139.1 - 2.5e-13 49.4 9.9 5.7e-13 48.2 6.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1681 PF07933.9 KII88140.1 - 2.8e-51 173.2 0.0 3.3e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PCI_Csn8 PF10075.4 KII88141.1 - 4e-11 42.8 0.0 1.3e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KII88141.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family RRM_1 PF00076.17 KII88143.1 - 1.3e-26 91.9 0.0 3.3e-14 52.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII88143.1 - 5.3e-21 74.3 0.0 2e-10 40.4 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII88143.1 - 1.4e-13 50.4 0.0 2.8e-07 30.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KII88143.1 - 0.0053 16.4 0.1 0.41 10.4 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 RRM_3 PF08777.6 KII88143.1 - 0.0065 16.2 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif CAP_GLY PF01302.20 KII88144.1 - 2.6e-20 71.9 0.5 4.3e-20 71.1 0.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KII88144.1 - 5.5e-09 35.4 2.7 0.0016 17.9 0.9 5.2 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII88144.1 - 3.5e-05 23.4 4.5 0.049 13.4 0.4 5.1 3 2 2 6 6 6 3 Leucine rich repeat LRR_9 PF14580.1 KII88144.1 - 0.00021 20.8 0.0 0.00049 19.6 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat CTV_P6 PF06706.6 KII88144.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein LRR_6 PF13516.1 KII88144.1 - 0.34 11.0 2.0 76 3.8 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich repeat ECH_C PF13766.1 KII88145.1 - 4e-29 101.1 0.0 4.6e-28 97.7 0.0 2.6 3 0 0 3 3 3 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KII88145.1 - 4.1e-27 94.8 0.0 1.1e-26 93.4 0.0 1.7 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase family IDO PF01231.13 KII88146.1 - 3.1e-104 348.7 0.0 3.5e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.5 KII88147.1 - 7.3e-52 174.9 2.9 4.2e-50 169.2 0.7 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KII88147.1 - 8e-20 70.5 0.6 1.7e-19 69.4 0.4 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KII88147.1 - 1.3e-14 53.8 0.0 4e-13 49.0 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain HSDR_N PF04313.9 KII88147.1 - 0.023 14.4 1.0 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF4539 PF15072.1 KII88147.1 - 0.085 12.5 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) NUDIX PF00293.23 KII88148.1 - 3.7e-19 68.7 0.0 6.6e-16 58.1 0.0 2.5 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KII88148.1 - 0.044 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain FF PF01846.14 KII88148.1 - 0.13 12.1 0.2 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 FF domain DUF1989 PF09347.5 KII88150.1 - 1.4e-52 177.5 0.0 1.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) COesterase PF00135.23 KII88153.1 - 1e-96 324.7 0.0 1.4e-96 324.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII88153.1 - 4.6e-09 36.1 0.6 8.4e-09 35.3 0.4 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII88153.1 - 1.6e-07 30.7 0.2 3.1e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII88153.1 - 0.021 14.6 0.2 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family SKIP_SNW PF02731.10 KII88154.1 - 3.6e-66 221.5 0.8 3.6e-66 221.5 0.5 2.4 2 0 0 2 2 2 1 SKIP/SNW domain COesterase PF00135.23 KII88155.1 - 1.3e-101 340.9 0.1 1.5e-99 334.1 0.0 2.7 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII88155.1 - 1e-09 38.2 1.3 1.7e-09 37.5 0.9 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII88155.1 - 1.5e-06 27.5 0.8 3.5e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII88155.1 - 0.02 14.6 0.5 0.043 13.5 0.3 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family SNF2_N PF00176.18 KII88156.1 - 1.4e-47 162.0 0.1 1.1e-38 132.7 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KII88156.1 - 5.4e-06 26.1 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII88156.1 - 9.4e-06 25.2 0.0 3.8e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII88156.1 - 0.16 11.7 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pam17 PF08566.5 KII88157.1 - 3.7e-62 209.0 0.0 4.8e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2833 PF11090.3 KII88157.1 - 0.11 12.6 0.1 1.5 9.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2833) SH3_9 PF14604.1 KII88158.1 - 1.1e-07 31.2 0.0 1.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII88158.1 - 0.0057 16.1 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII88158.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 SH3 domain DUF3292 PF11696.3 KII88158.1 - 0.05 11.4 2.5 0.029 12.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Meckelin PF09773.4 KII88158.1 - 0.079 10.7 0.0 0.1 10.3 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) AAA_5 PF07728.9 KII88159.1 - 3.6e-12 46.2 0.0 5.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KII88159.1 - 1.1e-09 38.3 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KII88159.1 - 3.5e-07 30.4 0.0 6.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII88159.1 - 1.2e-05 25.4 0.0 5.1e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KII88159.1 - 3e-05 24.1 0.0 0.00078 19.4 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KII88159.1 - 0.00053 19.8 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KII88159.1 - 0.0016 17.2 0.0 0.0071 15.0 0.0 1.7 1 1 0 2 2 2 1 PrkA AAA domain RNA_helicase PF00910.17 KII88159.1 - 0.0051 16.9 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KII88159.1 - 0.0076 16.1 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KII88159.1 - 0.015 14.4 0.0 0.054 12.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KII88159.1 - 0.016 16.0 0.0 0.037 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KII88159.1 - 0.03 14.6 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Sigma54_activat PF00158.21 KII88159.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KII88159.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Ank PF00023.25 KII88159.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat zf-CCCH PF00642.19 KII88160.1 - 3.6e-06 26.5 0.5 5.5e-06 25.9 0.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF836 PF05768.9 KII88161.1 - 2e-12 47.1 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 KII88161.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain zf-CCHC PF00098.18 KII88161.1 - 0.039 13.8 0.5 0.061 13.2 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII88161.1 - 0.075 12.7 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Thioredoxin_2 PF13098.1 KII88161.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Abhydrolase_3 PF07859.8 KII88162.1 - 1.4e-11 44.4 0.2 6.7e-11 42.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KII88162.1 - 2.1e-08 33.3 0.0 3.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 KII88162.1 - 9.4e-07 28.6 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII88162.1 - 3.2e-05 22.8 2.8 9e-05 21.3 1.9 1.6 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.6 KII88162.1 - 0.00029 19.7 0.0 0.00043 19.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 KII88162.1 - 0.0025 17.7 0.1 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4013 PF13197.1 KII88163.1 - 0.015 14.6 1.3 0.015 14.6 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) EphA2_TM PF14575.1 KII88163.1 - 0.016 15.5 0.2 0.14 12.5 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KII88163.1 - 0.6 9.7 2.6 0.49 10.0 0.2 1.9 2 0 0 2 2 2 0 Syndecan domain PROL5-SMR PF15621.1 KII88163.1 - 0.66 10.4 6.7 1.5 9.2 0.6 2.6 2 1 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Gly-zipper_Omp PF13488.1 KII88163.1 - 0.76 9.4 8.6 0.1 12.2 2.6 2.0 2 0 0 2 2 2 0 Glycine zipper DUF4328 PF14219.1 KII88163.1 - 1.8 7.8 9.0 0.16 11.2 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) Beta-APP PF03494.8 KII88163.1 - 2.9 7.4 5.6 4.9 6.7 3.9 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SMN PF06003.7 KII88164.1 - 0.023 13.8 5.4 0.032 13.3 3.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) COX15-CtaA PF02628.10 KII88164.1 - 0.038 12.8 0.5 0.05 12.4 0.2 1.3 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein COPI_assoc PF08507.5 KII88164.1 - 0.047 13.3 3.5 0.18 11.4 0.7 2.1 2 0 0 2 2 2 0 COPI associated protein DUF2020 PF09449.5 KII88165.1 - 0.018 14.7 0.0 0.053 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Rdx PF10262.4 KII88165.1 - 0.59 10.1 0.0 0.59 10.1 0.0 3.6 3 0 0 3 3 3 0 Rdx family Methyltransf_30 PF05430.6 KII88166.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Radical_SAM PF04055.16 KII88167.1 - 2.4e-16 60.3 0.1 1e-15 58.3 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KII88167.1 - 2.9e-12 46.4 0.1 8.4e-12 44.9 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII88167.1 - 0.019 15.0 0.0 0.063 13.4 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII88167.1 - 0.033 13.9 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF2404 PF10296.4 KII88168.1 - 0.00013 21.9 0.0 0.0019 18.2 0.0 2.5 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) tRNA_Me_trans PF03054.11 KII88169.1 - 3.5e-117 390.9 0.0 4.1e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 KII88169.1 - 3.2e-07 29.5 0.0 3.9e-05 22.6 0.0 2.5 2 1 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 KII88169.1 - 0.0053 16.2 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 KII88169.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 KII88169.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Mit_ribos_Mrp51 PF11709.3 KII88170.1 - 2.2e-27 96.1 0.5 3.2e-27 95.5 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Nuc_sug_transp PF04142.10 KII88171.1 - 2.5e-77 259.2 6.4 3.5e-77 258.7 4.5 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KII88171.1 - 7.8e-08 31.5 7.9 1.1e-07 31.0 5.5 1.1 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KII88171.1 - 4.3e-06 26.8 5.0 4.3e-06 26.8 3.4 2.8 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KII88171.1 - 2.2e-05 24.4 4.3 2.2e-05 24.4 3.0 2.5 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 KII88171.1 - 0.00024 20.7 3.4 0.00024 20.7 2.4 3.0 3 1 0 3 3 3 1 Triose-phosphate Transporter family WD40 PF00400.27 KII88172.1 - 2.3e-05 24.0 0.7 2 8.4 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat GDA1_CD39 PF01150.12 KII88173.1 - 1.9e-100 336.4 0.0 1.9e-93 313.3 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KII88173.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Fungal_trans PF04082.13 KII88176.1 - 5.4e-19 68.0 0.3 1e-18 67.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII88176.1 - 1.9e-05 24.4 7.3 3.6e-05 23.5 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 KII88176.1 - 9.8 4.8 10.6 1.3 7.8 3.1 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 KII88179.1 - 4.7e-58 191.1 28.0 6e-11 41.7 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KII88179.1 - 1.8e-13 49.9 1.5 4.2e-13 48.7 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88179.1 - 3.9e-12 45.5 1.1 8.5e-12 44.4 0.8 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KII88179.1 - 2.5e-06 25.9 15.7 0.035 12.2 0.1 6.1 3 3 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII88179.1 - 7.6e-05 21.6 0.2 0.65 8.6 0.0 4.0 3 2 1 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 KII88179.1 - 0.0043 16.5 2.0 1.6 8.1 0.4 3.0 2 1 0 2 2 2 2 PQQ-like domain DUF2457 PF10446.4 KII88179.1 - 2.4 6.8 17.4 0.07 11.8 7.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ebola_NP PF05505.7 KII88179.1 - 9.2 4.1 5.3 14 3.6 3.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Pro_isomerase PF00160.16 KII88180.1 - 2.3e-51 174.0 0.0 2.5e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tyr_Deacylase PF02580.11 KII88181.1 - 9.3e-48 161.8 0.0 1.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PLDc_2 PF13091.1 KII88182.1 - 1.4e-12 47.5 0.0 1.9e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KII88182.1 - 8.1e-07 28.6 0.0 0.011 15.4 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif WD40 PF00400.27 KII88183.1 - 1.7e-47 157.6 32.2 4.5e-10 39.0 0.0 8.4 7 1 1 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KII88183.1 - 1.4e-10 39.9 11.6 0.0067 14.6 0.1 5.2 3 3 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII88183.1 - 8.1e-05 21.5 0.8 0.16 10.7 0.0 3.5 2 2 2 4 4 4 2 Nup133 N terminal like AsnC_trans_reg PF01037.16 KII88183.1 - 0.11 12.2 0.0 7.8 6.2 0.0 2.8 3 0 0 3 3 3 0 AsnC family PQQ_3 PF13570.1 KII88183.1 - 0.13 12.6 12.2 1.8 8.9 0.1 5.3 7 0 0 7 7 7 0 PQQ-like domain adh_short_C2 PF13561.1 KII88184.1 - 7.3e-32 111.0 0.1 8.4e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII88184.1 - 1.4e-16 60.8 1.2 2e-16 60.3 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII88184.1 - 6.1e-05 22.7 0.1 9.7e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 KR domain Oxidored_nitro PF00148.14 KII88184.1 - 0.0044 15.7 0.0 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.16 KII88184.1 - 0.0093 15.8 0.4 0.016 15.0 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 KII88184.1 - 0.013 14.9 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII88184.1 - 0.018 15.0 1.4 0.029 14.3 1.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KII88184.1 - 0.06 12.9 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII88184.1 - 0.078 12.1 0.2 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KII88184.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GRDA PF04723.9 KII88184.1 - 0.12 12.0 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A adh_short_C2 PF13561.1 KII88185.1 - 2.5e-31 109.3 1.0 2.9e-31 109.0 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII88185.1 - 2.9e-12 46.8 5.4 4.3e-12 46.2 3.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KII88185.1 - 0.0017 18.0 0.5 0.0041 16.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Oxidored_nitro PF00148.14 KII88185.1 - 0.0054 15.4 0.2 0.0097 14.5 0.1 1.4 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.1 KII88185.1 - 0.018 15.0 3.0 0.038 14.0 2.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KII88185.1 - 0.023 14.3 1.3 0.023 14.3 0.9 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KII88185.1 - 0.026 13.6 0.2 0.043 12.8 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KII88185.1 - 0.093 12.1 0.5 0.5 9.7 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-C3HC4_3 PF13920.1 KII88186.1 - 5.8e-09 35.4 15.7 9.7e-09 34.7 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII88186.1 - 1.1 9.3 18.3 1.9 8.5 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyclin PF08613.6 KII88189.1 - 1.7e-12 48.0 0.7 4.7e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KII88189.1 - 6.2e-11 41.9 0.0 9.9e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Virulence_RhuM PF13310.1 KII88189.1 - 0.042 12.8 0.0 0.083 11.8 0.0 1.4 1 1 0 1 1 1 0 Virulence protein RhuM family Gag_spuma PF03276.9 KII88189.1 - 0.32 9.2 5.3 0.44 8.8 3.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein zf-C4H2 PF10146.4 KII88190.1 - 3e-06 27.4 0.4 3e-06 27.4 0.3 1.7 2 0 0 2 2 2 1 Zinc finger-containing protein TBPIP PF07106.8 KII88190.1 - 0.11 12.0 3.3 0.16 11.5 2.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pex14_N PF04695.8 KII88190.1 - 1.5 8.9 6.0 1.4 8.9 3.1 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AT_hook PF02178.14 KII88190.1 - 2 8.3 9.0 5.1 7.1 6.2 1.7 1 0 0 1 1 1 0 AT hook motif Acetyltransf_1 PF00583.19 KII88191.1 - 5.6e-09 35.9 0.1 9.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KII88191.1 - 0.00024 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KII88191.1 - 0.00074 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII88191.1 - 0.024 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII88191.1 - 0.037 13.8 0.3 0.074 12.9 0.2 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3608 PF12257.3 KII88192.1 - 1.4e-64 217.6 0.0 2.4e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KII88192.1 - 1.4e-16 59.9 0.1 2.8e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_6 PF01341.12 KII88193.1 - 2.3e-110 368.7 1.5 2.9e-110 368.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 F-box-like PF12937.2 KII88197.1 - 2.3e-07 30.4 1.1 4.6e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like ADIP PF11559.3 KII88197.1 - 0.58 10.0 5.5 0.94 9.3 3.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding F-box-like PF12937.2 KII88198.1 - 7.3e-08 32.0 0.1 1.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like Cortex-I_coil PF09304.5 KII88198.1 - 0.1 12.6 0.2 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil VRR_NUC PF08774.6 KII88201.1 - 1.2e-20 73.3 0.0 4.8e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 VRR-NUC domain SAP PF02037.22 KII88201.1 - 0.0013 18.2 0.1 0.0044 16.4 0.1 2.0 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 KII88201.1 - 0.0016 18.1 3.0 0.0047 16.6 0.4 2.5 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain AAA_11 PF13086.1 KII88202.1 - 7.6e-51 172.9 1.1 1.1e-50 172.4 0.7 1.2 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 KII88202.1 - 6.9e-28 97.1 0.3 2.9e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 KII88202.1 - 9.2e-15 54.1 0.1 1.6e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KII88202.1 - 1e-10 41.5 0.1 6.6e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KII88202.1 - 1.7e-08 34.5 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KII88202.1 - 4e-05 23.3 0.1 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.4 KII88202.1 - 4.8e-05 22.4 0.0 0.00018 20.6 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KII88202.1 - 8.3e-05 22.0 0.1 0.00033 20.0 0.0 1.9 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KII88202.1 - 0.0027 17.2 0.6 0.008 15.6 0.4 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII88202.1 - 0.0043 17.1 0.1 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII88202.1 - 0.016 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KII88202.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 KII88202.1 - 0.028 13.6 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 KII88202.1 - 0.03 14.5 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KII88202.1 - 0.047 13.1 0.0 0.099 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain KaiC PF06745.8 KII88202.1 - 0.048 12.7 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 KII88202.1 - 0.054 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KII88202.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KII88202.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_12 PF13087.1 KII88203.1 - 2.8e-27 95.4 0.0 4.7e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RTA1 PF04479.8 KII88204.1 - 1.6e-49 168.4 8.7 1.6e-49 168.4 6.0 1.3 2 0 0 2 2 2 1 RTA1 like protein Flu_C_NS1 PF03506.8 KII88204.1 - 0.14 11.8 0.3 0.34 10.6 0.1 1.7 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) RTA1 PF04479.8 KII88205.1 - 5e-49 166.8 10.2 7.1e-49 166.3 7.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Flu_C_NS1 PF03506.8 KII88205.1 - 0.0064 16.2 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 Influenza C non-structural protein (NS1) MtrF PF09472.5 KII88205.1 - 0.11 11.7 0.8 11 5.3 0.3 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PhrC_PhrF PF11131.3 KII88205.1 - 0.29 10.7 4.3 0.26 10.9 0.4 2.4 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF3995 PF13160.1 KII88205.1 - 2.8 8.0 7.2 1.1 9.3 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) FAD_binding_3 PF01494.14 KII88206.1 - 3.5e-69 233.5 0.0 4.6e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KII88206.1 - 0.00035 19.7 0.0 0.00062 18.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KII88206.1 - 0.00052 19.9 0.2 0.029 14.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII88206.1 - 0.00065 20.0 0.1 0.72 10.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII88206.1 - 0.00088 19.2 0.0 0.0031 17.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII88206.1 - 0.00099 18.1 2.3 0.13 11.1 0.3 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KII88206.1 - 0.0031 16.0 0.1 0.012 14.1 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KII88206.1 - 0.0064 15.3 1.2 0.013 14.3 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KII88206.1 - 0.11 11.3 0.2 0.18 10.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KII88207.1 - 4.5e-63 213.4 0.0 6.1e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KII88207.1 - 0.00041 20.6 0.1 2.3 8.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII88207.1 - 0.00073 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII88207.1 - 0.0016 17.5 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KII88207.1 - 0.0018 16.8 0.1 0.007 14.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KII88207.1 - 0.0032 16.3 0.6 0.0053 15.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII88207.1 - 0.0035 17.2 0.2 0.068 13.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII88207.1 - 0.007 15.3 2.8 0.18 10.6 0.1 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KII88207.1 - 0.075 12.0 0.2 0.13 11.3 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KII88207.1 - 0.086 11.6 0.3 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Hydrolase PF00702.21 KII88208.1 - 1.4e-14 55.0 1.4 2.4e-07 31.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII88208.1 - 8.9e-14 52.0 0.1 4e-13 49.9 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII88208.1 - 1.2e-11 44.4 0.0 2.9e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KII88208.1 - 6.6e-10 38.4 1.3 2.1e-09 36.7 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KII88208.1 - 7.3e-05 22.4 1.4 0.0034 17.0 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ricin_B_lectin PF00652.17 KII88210.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain F-box-like PF12937.2 KII88212.1 - 0.64 9.7 6.7 0.61 9.8 0.2 2.6 2 0 0 2 2 2 0 F-box-like Leu_leader PF08054.6 KII88212.1 - 9.2 6.0 7.2 0.51 10.0 0.5 2.1 2 0 0 2 2 2 0 Leucine operon leader peptide GPI-anchored PF10342.4 KII88214.1 - 2.1e-06 28.1 0.0 2.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII88214.1 - 0.00029 20.3 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KII88215.1 - 1.7e-06 28.3 0.0 2.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII88215.1 - 0.00035 20.1 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3429 PF11911.3 KII88216.1 - 4.4e-36 123.9 15.1 6e-36 123.5 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF2378 PF09536.5 KII88216.1 - 0.007 15.9 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2378) GPI-anchored PF10342.4 KII88217.1 - 9.7e-05 22.7 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII88217.1 - 0.00046 19.7 0.0 0.0005 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Pkinase PF00069.20 KII88218.1 - 1.5e-11 44.0 0.0 1e-10 41.2 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88218.1 - 3.7e-05 22.9 0.0 6.3e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII88218.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KII88221.1 - 1.1e-11 44.3 0.0 6.7e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII88221.1 - 0.00031 19.8 0.0 0.00058 19.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF948 PF06103.6 KII88222.1 - 0.077 12.8 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 KII88223.1 - 1.9e-09 37.0 0.0 7.3e-08 31.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII88223.1 - 6.6e-05 22.0 0.0 0.00012 21.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.1 KII88224.1 - 1.1e-08 34.4 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII88224.1 - 5e-07 29.0 0.0 8.2e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII88224.1 - 8.4e-06 25.1 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1180 PF06679.7 KII88224.1 - 0.00053 19.9 7.9 0.00053 19.9 5.4 3.1 2 1 1 3 3 2 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.1 KII88224.1 - 0.0027 18.0 0.2 0.0063 16.8 0.0 1.7 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 KII88224.1 - 0.0035 17.0 3.5 0.012 15.2 2.3 1.8 1 1 1 2 2 2 1 Rifin/stevor family NfeD PF01957.13 KII88224.1 - 0.016 15.3 1.3 0.025 14.6 0.2 1.9 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Amnionless PF14828.1 KII88224.1 - 0.025 13.0 0.1 0.039 12.4 0.1 1.3 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.1 KII88224.1 - 0.034 13.8 11.5 0.76 9.4 7.7 2.6 1 1 0 1 1 1 0 TMEM154 protein family Cytomega_TRL10 PF06084.6 KII88224.1 - 0.038 13.7 0.2 0.038 13.7 0.1 1.7 2 0 0 2 2 1 0 Cytomegalovirus TRL10 protein FAM176 PF14851.1 KII88224.1 - 0.062 12.9 1.5 0.64 9.6 0.4 2.4 2 0 0 2 2 2 0 FAM176 family ATG27 PF09451.5 KII88224.1 - 0.065 12.4 0.2 0.1 11.8 0.0 1.4 2 0 0 2 2 1 0 Autophagy-related protein 27 Meckelin PF09773.4 KII88224.1 - 0.081 10.6 0.0 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF912 PF06024.7 KII88224.1 - 0.14 12.1 0.7 0.69 9.9 0.0 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SH3_9 PF14604.1 KII88225.1 - 7.7e-10 38.2 0.0 1.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII88225.1 - 1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII88225.1 - 1.6e-06 27.4 0.6 2.9e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Rifin_STEVOR PF02009.11 KII88225.1 - 0.00035 20.3 0.5 0.00058 19.6 0.3 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF1180 PF06679.7 KII88225.1 - 0.0034 17.2 11.2 0.0034 17.2 7.8 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1180) DUF912 PF06024.7 KII88225.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vpu PF00558.14 KII88225.1 - 0.11 12.0 1.5 0.27 10.8 0.3 1.9 2 0 0 2 2 2 0 Vpu protein Herpes_BLLF1 PF05109.8 KII88225.1 - 2.9 5.7 48.6 4.5 5.1 33.7 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) IER PF05760.7 KII88225.1 - 3.2 7.6 11.1 4.7 7.0 7.7 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) TMEM154 PF15102.1 KII88225.1 - 6.6 6.4 17.8 1.2e+02 2.3 12.4 2.5 1 1 0 1 1 1 0 TMEM154 protein family WD40 PF00400.27 KII88226.1 - 1.5e-41 138.8 25.9 1.6e-08 34.0 0.0 8.3 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 KII88226.1 - 4.4e-11 42.3 0.5 1.1e-10 41.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88226.1 - 1.6e-05 24.4 0.3 4.8e-05 22.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KII88226.1 - 0.015 13.4 0.0 1.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF1258 PF06869.7 KII88226.1 - 0.047 12.7 0.0 0.89 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) DUF2457 PF10446.4 KII88226.1 - 1.3 7.6 5.9 1.8 7.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_Rpc34 PF05158.7 KII88227.1 - 6.4e-75 252.3 3.1 2.9e-64 217.3 0.3 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 KII88227.1 - 0.028 14.2 0.2 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC MIP-T3 PF10243.4 KII88227.1 - 0.031 12.7 59.5 0.049 12.1 41.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HxlR PF01638.12 KII88227.1 - 0.089 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix UPAR_LY6 PF00021.16 KII88228.1 - 0.015 15.7 0.2 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 u-PAR/Ly-6 domain DUF1878 PF08963.5 KII88229.1 - 0.021 15.0 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Pkinase PF00069.20 KII88230.1 - 1.2e-11 44.2 0.0 5.8e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII88230.1 - 0.00035 19.7 0.0 0.00062 18.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RCR PF12273.3 KII88231.1 - 0.028 14.9 0.6 0.051 14.1 0.4 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Neur_chan_memb PF02932.11 KII88231.1 - 0.037 13.9 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAA_hydrolase PF01557.13 KII88232.1 - 9.9e-58 195.1 0.0 1.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 KII88232.1 - 0.00035 20.0 0.4 0.0048 16.4 0.1 2.2 2 0 0 2 2 2 1 KH domain DsrH PF04077.7 KII88232.1 - 0.043 13.4 0.1 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein SAPS PF04499.10 KII88233.1 - 2.6e-129 431.9 0.0 4.3e-129 431.2 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein YL1 PF05764.8 KII88233.1 - 7.5 6.0 7.5 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Adap_comp_sub PF00928.16 KII88234.1 - 5.6e-86 287.8 0.2 7.2e-86 287.5 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KII88234.1 - 2e-06 27.5 2.7 3.5e-06 26.8 1.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GPI-anchored PF10342.4 KII88235.1 - 1.3e-10 41.6 0.4 1.7e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HMG_box PF00505.14 KII88236.1 - 2e-13 50.3 0.7 6.9e-13 48.6 0.5 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII88236.1 - 1.9e-10 40.9 0.0 5.9e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain FAD_binding_3 PF01494.14 KII88237.1 - 1.8e-50 171.9 0.0 2.8e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII88237.1 - 8.8e-10 38.0 4.5 0.00042 19.3 1.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII88237.1 - 2.7e-07 30.8 0.1 4.9e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII88237.1 - 4.9e-06 26.5 0.2 1.3e-05 25.1 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII88237.1 - 5e-06 25.2 0.6 0.019 13.4 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 KII88237.1 - 9.5e-05 21.6 1.6 0.00013 21.2 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII88237.1 - 0.0002 20.5 0.0 0.022 13.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KII88237.1 - 0.00071 18.5 2.6 0.0014 17.5 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KII88237.1 - 0.0024 17.6 0.4 0.2 11.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KII88237.1 - 0.0026 16.7 3.5 0.018 13.9 1.1 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KII88237.1 - 0.0029 17.9 0.7 1.9 8.9 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII88237.1 - 0.0048 16.8 0.5 0.011 15.7 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KII88237.1 - 0.0082 15.9 0.6 0.02 14.7 0.3 1.8 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 KII88237.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KII88237.1 - 0.027 13.5 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 KII88237.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 KII88237.1 - 0.28 9.9 2.4 0.44 9.3 1.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PAP_assoc PF03828.14 KII88238.1 - 1.6e-18 66.4 0.1 4.7e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KII88238.1 - 5.2e-08 33.1 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Methyltransf_31 PF13847.1 KII88239.1 - 1.4e-11 44.1 0.0 2.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII88239.1 - 9.6e-11 41.3 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KII88239.1 - 5.9e-10 39.5 0.0 1.3e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII88239.1 - 1.6e-09 38.3 0.1 3.8e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII88239.1 - 1.1e-08 34.9 0.0 1e-07 31.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII88239.1 - 1.8e-08 34.4 0.0 5.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII88239.1 - 4.9e-06 26.0 0.0 8.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KII88239.1 - 5e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KII88239.1 - 0.00036 19.3 0.0 0.00057 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KII88239.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII88239.1 - 0.0058 15.7 0.1 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 KII88239.1 - 0.0071 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PRMT5 PF05185.11 KII88239.1 - 0.033 13.0 0.0 0.068 12.0 0.0 1.7 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.10 KII88239.1 - 0.044 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 KII88239.1 - 0.05 14.4 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KII88239.1 - 0.054 13.4 0.1 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 KII88239.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KII88239.1 - 0.094 12.1 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 KII88239.1 - 0.11 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase F-box-like PF12937.2 KII88240.1 - 7.8e-09 35.1 0.2 1.3e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88240.1 - 5.8e-05 22.6 0.0 9.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain DUF390 PF04094.9 KII88240.1 - 0.16 9.9 0.0 0.19 9.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Nbl1_Borealin_N PF10444.4 KII88241.1 - 1.9e-06 27.1 0.0 3.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Ribosomal_S3Ae PF01015.13 KII88241.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family 3Beta_HSD PF01073.14 KII88242.1 - 2.4e-64 216.7 0.0 1.1e-58 198.2 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII88242.1 - 2.3e-34 118.8 0.0 5.8e-34 117.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII88242.1 - 9.8e-18 64.8 0.1 1.4e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII88242.1 - 3.8e-14 52.2 0.1 6.4e-11 41.6 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KII88242.1 - 1.1e-11 44.2 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KII88242.1 - 1.4e-05 24.1 0.0 5e-05 22.3 0.1 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KII88242.1 - 0.0011 18.8 0.7 0.042 13.7 0.5 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KII88242.1 - 0.016 14.4 0.2 0.083 12.1 0.1 1.9 1 1 0 1 1 1 0 NmrA-like family KR PF08659.5 KII88242.1 - 0.037 13.7 0.5 0.34 10.5 0.2 2.3 1 1 1 2 2 2 0 KR domain TPP_enzyme_N PF02776.13 KII88244.1 - 1.1e-56 190.9 0.0 4.6e-56 188.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KII88244.1 - 9e-49 164.9 0.3 3.8e-47 159.6 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KII88244.1 - 3.9e-37 127.0 1.1 1.8e-36 124.9 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF438 PF04282.8 KII88245.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF438) TYW3 PF02676.9 KII88246.1 - 0.0089 15.1 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Hema_esterase PF03996.10 KII88246.1 - 0.033 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin esterase DUF481 PF04338.7 KII88247.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF481 VP40 PF07447.7 KII88248.1 - 0.13 11.3 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 Matrix protein VP40 Toxin_16 PF07945.6 KII88251.1 - 0.78 9.4 3.4 13 5.5 0.8 2.5 2 0 0 2 2 2 0 Janus-atracotoxin Retinal PF15449.1 KII88255.1 - 2.5 5.6 10.6 3.2 5.2 7.4 1.1 1 0 0 1 1 1 0 Retinal protein F-box-like PF12937.2 KII88259.1 - 0.00038 20.1 0.1 0.0015 18.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like SRPRB PF09439.5 KII88260.1 - 2.8e-21 75.5 0.0 4.7e-21 74.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KII88260.1 - 8.7e-11 41.3 0.0 1.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KII88260.1 - 6.5e-09 35.7 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KII88260.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KII88260.1 - 3.6e-07 30.6 0.0 7.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KII88260.1 - 2e-05 24.4 0.0 0.23 11.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin family TIP49 PF06068.8 KII88260.1 - 0.00071 18.4 0.0 0.00097 17.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KII88260.1 - 0.002 18.3 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 KII88260.1 - 0.0025 17.2 0.0 2.1 7.7 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KII88260.1 - 0.0037 16.5 0.0 0.011 14.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_25 PF13481.1 KII88260.1 - 0.0057 16.0 0.1 0.014 14.8 0.1 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KII88260.1 - 0.025 14.5 0.1 0.055 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KII88260.1 - 0.041 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KII88260.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 KII88260.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KII88260.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 KII88260.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Ras family E1_dh PF00676.15 KII88261.1 - 3.9e-113 377.1 0.0 4.6e-113 376.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KII88261.1 - 0.00068 18.6 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KII88261.1 - 0.0014 18.2 0.6 0.003 17.1 0.4 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4598 PF15370.1 KII88262.1 - 5.3e-14 52.4 0.4 5.3e-14 52.4 0.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) HEAT_2 PF13646.1 KII88263.1 - 3.2e-15 56.1 21.3 0.00025 21.2 0.2 7.5 5 1 2 7 7 7 3 HEAT repeats HEAT PF02985.17 KII88263.1 - 7e-15 53.7 30.8 0.00014 21.6 0.1 10.6 11 0 0 11 11 11 3 HEAT repeat Arm PF00514.18 KII88263.1 - 5.8e-14 51.3 21.4 3.6e-05 23.4 0.1 8.6 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KII88263.1 - 3.5e-09 35.5 5.8 3e-06 25.8 0.3 5.3 3 1 1 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 KII88263.1 - 1.3e-08 34.8 1.2 0.0057 16.5 0.0 4.4 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KII88263.1 - 6.5e-08 31.2 2.8 0.0065 14.7 0.0 3.8 2 1 2 4 4 4 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 KII88263.1 - 3.7e-05 24.0 30.6 0.00058 20.2 0.1 7.4 8 0 0 8 8 8 2 HEAT-like repeat V-ATPase_H_C PF11698.3 KII88263.1 - 0.00017 21.4 3.0 4.1 7.3 0.0 5.0 5 1 1 6 6 6 2 V-ATPase subunit H Arm_2 PF04826.8 KII88263.1 - 0.0036 16.4 0.1 0.14 11.2 0.1 2.5 1 1 1 2 2 2 2 Armadillo-like IBN_N PF03810.14 KII88263.1 - 0.011 15.5 0.1 0.16 11.8 0.1 3.0 3 0 0 3 3 3 0 Importin-beta N-terminal domain DUF3361 PF11841.3 KII88263.1 - 0.088 12.5 0.7 1.9 8.2 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3361) DRIM PF07539.7 KII88263.1 - 0.13 11.6 0.1 8.1 5.8 0.0 3.1 2 0 0 2 2 2 0 Down-regulated in metastasis DUF1641 PF07849.6 KII88263.1 - 0.16 11.5 0.0 0.42 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF3808 PF10300.4 KII88264.1 - 5e-77 259.4 0.0 6.5e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KII88264.1 - 0.00018 21.1 1.3 0.017 14.7 0.0 3.6 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 KII88264.1 - 0.00093 19.4 0.3 0.83 10.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII88264.1 - 0.026 14.4 0.6 18 5.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KII88264.1 - 0.45 11.2 6.4 2.2 9.0 0.2 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat CoaE PF01121.15 KII88266.1 - 1.6e-63 213.3 0.0 1.9e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KII88266.1 - 3.6e-06 27.3 0.0 1.5e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII88266.1 - 9.7e-05 23.1 0.1 0.0005 20.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 KII88266.1 - 0.052 13.4 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.1 KII88266.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.12 KII88267.1 - 2.2e-35 120.9 1.1 4e-35 120.1 0.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Orthopox_A5L PF06193.6 KII88267.1 - 0.043 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Ets PF00178.17 KII88267.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Arrestin_C PF02752.17 KII88269.1 - 6.5e-09 36.0 0.0 8.6e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KII88269.1 - 2.6e-05 24.0 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KII88269.1 - 0.0026 17.2 0.0 0.0084 15.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like DUF382 PF04037.8 KII88270.1 - 3.7e-61 204.6 0.5 3.7e-61 204.6 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KII88270.1 - 3.2e-18 64.8 6.5 6.1e-18 63.9 4.5 1.5 1 0 0 1 1 1 1 PSP MitMem_reg PF13012.1 KII88271.1 - 3.1e-37 127.1 0.6 6.2e-37 126.2 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KII88271.1 - 2.6e-27 94.8 0.0 5.2e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-CCHC PF00098.18 KII88272.1 - 2.4e-50 166.1 55.5 9.9e-08 31.5 1.2 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KII88272.1 - 1.1e-13 50.5 43.9 0.06 13.0 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KII88272.1 - 2.2e-08 33.6 36.2 0.1 12.3 0.3 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 KII88272.1 - 1.5e-05 24.5 49.8 0.13 11.9 0.6 7.4 5 2 2 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 KII88272.1 - 5.4e-05 22.5 37.9 0.12 11.9 0.3 7.1 3 2 4 7 7 7 5 Zinc knuckle COX4 PF02936.9 KII88273.1 - 7.6e-35 119.7 0.0 9.2e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.8 KII88273.1 - 0.002 18.0 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1138) PEHE PF15275.1 KII88273.1 - 0.03 14.7 0.5 0.05 14.0 0.3 1.3 1 0 0 1 1 1 0 PEHE domain DUF1289 PF06945.8 KII88273.1 - 4.9 6.6 6.4 1.2 8.6 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) ATP-synt_Eps PF04627.8 KII88274.1 - 1.7e-19 69.1 3.2 2.5e-19 68.5 2.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.17 KII88275.1 - 6.6e-52 175.1 0.0 7.8e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII88275.1 - 1.6e-14 54.4 0.0 2.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII88275.1 - 8.9e-12 44.5 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII88275.1 - 1.6e-05 24.4 0.0 0.00034 20.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII88275.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KII88275.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DSPc PF00782.15 KII88276.1 - 5.8e-27 93.8 0.0 6.4e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII88276.1 - 0.00051 19.4 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KII88276.1 - 0.042 12.7 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 KII88276.1 - 0.096 12.9 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family DEAD PF00270.24 KII88277.1 - 7.7e-43 145.9 3.2 1.8e-42 144.6 0.7 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII88277.1 - 1.9e-26 91.6 0.3 7.2e-26 89.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KII88277.1 - 0.00067 19.3 0.6 0.0019 17.9 0.1 2.0 1 1 1 2 2 2 1 Part of AAA domain ResIII PF04851.10 KII88277.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KII88277.1 - 0.0069 15.9 0.7 0.019 14.5 0.3 1.9 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 KII88277.1 - 0.027 14.2 0.1 0.15 11.7 0.0 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.1 KII88277.1 - 0.029 14.4 0.2 0.14 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 KII88277.1 - 0.066 12.2 0.0 0.19 10.7 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 KII88277.1 - 0.077 12.2 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MFS_1 PF07690.11 KII88279.1 - 7.8e-28 97.1 76.9 1.9e-20 72.8 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TrbC PF04956.8 KII88279.1 - 0.0045 16.9 1.5 0.0045 16.9 1.0 3.3 3 2 0 3 3 3 1 TrbC/VIRB2 family DUF4583 PF15190.1 KII88279.1 - 0.12 12.0 1.7 0.31 10.6 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) Fibrillarin PF01269.12 KII88280.1 - 3e-104 346.9 0.0 3.4e-104 346.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KII88280.1 - 7.7e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KII88280.1 - 0.00025 20.6 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KII88280.1 - 0.00052 19.6 0.1 0.0018 17.8 0.0 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KII88280.1 - 0.0056 17.2 0.0 0.0083 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PMT PF02366.13 KII88281.1 - 2.5e-77 259.5 19.3 2.5e-77 259.5 13.4 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KII88281.1 - 2.1e-29 102.4 0.3 2.8e-29 101.9 0.2 1.2 1 0 0 1 1 1 1 MIR domain UCH PF00443.24 KII88282.1 - 1e-48 165.7 0.0 1.6e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII88282.1 - 6.1e-12 45.5 0.0 2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF1664 PF07889.7 KII88283.1 - 0.44 10.3 10.1 9.2 6.0 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KII88283.1 - 0.63 10.3 9.9 8.4 6.7 0.0 4.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_3 PF13920.1 KII88284.1 - 2.9e-05 23.6 7.7 2.9e-05 23.6 5.4 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) DUF605 PF04652.11 KII88284.1 - 1.1 8.6 14.5 5.9 6.1 6.1 2.3 2 0 0 2 2 2 0 Vta1 like ADH_zinc_N PF00107.21 KII88285.1 - 9.9e-21 73.6 1.0 3.8e-20 71.7 0.2 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII88285.1 - 1.9e-10 41.7 0.1 4.3e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII88285.1 - 3e-05 23.7 0.0 0.00028 20.5 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Choline_transpo PF04515.7 KII88286.1 - 7.1e-24 84.1 5.6 7.1e-24 84.1 3.9 2.0 2 1 0 2 2 2 1 Plasma-membrane choline transporter Ribosomal_L37 PF08561.5 KII88287.1 - 7.9e-21 73.4 0.2 1.5e-20 72.5 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 LRR_8 PF13855.1 KII88288.1 - 0.025 14.3 0.3 0.66 9.7 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat CBM_19 PF03427.8 KII88290.1 - 0.012 15.3 0.6 0.012 15.3 0.4 2.6 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) Utp21 PF04192.7 KII88291.1 - 2e-64 216.9 0.6 3.3e-64 216.2 0.4 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KII88291.1 - 2.9e-18 64.9 21.3 4.4e-06 26.3 0.0 9.6 9 1 0 9 9 9 5 WD domain, G-beta repeat Hira PF07569.6 KII88291.1 - 0.0015 17.7 1.3 1.2 8.3 0.0 3.8 4 0 0 4 4 4 1 TUP1-like enhancer of split Nucleoporin_N PF08801.6 KII88291.1 - 0.0029 16.4 3.1 6.1 5.4 0.0 4.8 2 2 3 5 5 5 1 Nup133 N terminal like Nup160 PF11715.3 KII88291.1 - 0.0058 14.8 1.4 1.8 6.5 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KII88291.1 - 0.039 14.2 0.1 1.1 9.6 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain eIF2A PF08662.6 KII88291.1 - 0.04 13.6 0.0 3.2 7.3 0.0 3.4 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF3509 PF12021.3 KII88291.1 - 0.077 12.7 0.5 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Tim17 PF02466.14 KII88292.1 - 0.038 14.0 3.0 0.089 12.8 0.0 2.4 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF1010 PF06231.6 KII88292.1 - 0.096 12.6 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) PQQ_3 PF13570.1 KII88293.1 - 9.1e-07 28.9 0.3 1.9 8.8 0.0 3.7 3 0 0 3 3 3 3 PQQ-like domain WD40 PF00400.27 KII88293.1 - 3.2e-06 26.7 0.6 0.41 10.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KII88293.1 - 0.00024 20.8 0.1 0.32 10.7 0.0 3.1 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region D-ser_dehydrat PF14031.1 KII88293.1 - 0.019 15.1 0.2 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Putative serine dehydratase domain Lipase_3 PF01764.20 KII88294.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KII88294.1 - 0.0042 16.8 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KII88294.1 - 0.005 16.5 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KII88294.1 - 0.0074 15.9 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Amidohydro_1 PF01979.15 KII88295.1 - 1.9e-42 146.0 0.2 2.6e-42 145.6 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KII88295.1 - 9.4e-09 34.9 0.1 1.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KII88295.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KII88295.1 - 0.00044 20.3 0.0 0.07 13.1 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase TauD PF02668.11 KII88296.1 - 3.2e-26 92.5 0.0 4.2e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family M20_dimer PF07687.9 KII88297.1 - 2.7e-07 30.3 0.1 5.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KII88297.1 - 1e-05 25.1 3.8 1.7e-05 24.4 2.7 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1905 PF08922.6 KII88297.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Fungal_trans PF04082.13 KII88298.1 - 1.3e-25 89.7 0.0 2.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII88298.1 - 2.7e-11 43.1 4.6 5.8e-11 42.1 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 KII88300.1 - 1e-36 125.9 0.9 2.1e-36 124.9 0.1 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase CTP_transf_2 PF01467.21 KII88301.1 - 2.5e-08 34.1 0.0 5.5e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase Gln-synt_C PF00120.19 KII88302.1 - 2.2e-56 190.8 0.0 2.1e-55 187.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain MARVEL PF01284.18 KII88303.1 - 1e-05 25.3 7.4 0.026 14.3 2.8 2.2 2 0 0 2 2 2 2 Membrane-associating domain NfeD PF01957.13 KII88303.1 - 0.34 11.0 0.8 0.51 10.4 0.0 1.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF3074 PF11274.3 KII88304.1 - 3.4e-36 124.5 0.1 4.7e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ribosomal_L27 PF01016.14 KII88305.1 - 1.3e-31 108.2 1.9 1.8e-31 107.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Skp1 PF01466.14 KII88306.1 - 1e-39 134.4 1.7 1.5e-39 133.8 1.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KII88306.1 - 1.1e-23 83.1 0.3 2.8e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 KII88306.1 - 0.00014 21.8 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.9 KII88306.1 - 0.08 12.5 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) mRNA_cap_enzyme PF01331.14 KII88307.1 - 5.9e-52 176.1 0.0 7.7e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KII88307.1 - 3.3e-17 62.7 0.0 6.7e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KII88307.1 - 1.7e-10 40.6 0.0 3.3e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF4149 PF13664.1 KII88310.1 - 4.5 7.3 9.3 3.4 7.7 4.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) HSF_DNA-bind PF00447.12 KII88312.1 - 1.4e-35 121.5 1.2 1.4e-35 121.5 0.8 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 KII88312.1 - 1.3e-22 79.9 0.0 4.2e-22 78.2 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PEP-utilisers_N PF05524.8 KII88312.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.2 4 0 0 4 4 4 0 PEP-utilising enzyme, N-terminal Peptidase_U4 PF03419.8 KII88315.1 - 0.5 9.3 6.2 0.63 9.0 4.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA COX2_TM PF02790.10 KII88315.1 - 3.6 7.6 7.2 23 5.0 0.1 2.5 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Exo_endo_phos PF03372.18 KII88317.1 - 7.2e-07 29.3 0.0 8.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.18 KII88319.1 - 3.7e-17 63.1 0.0 4.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.15 KII88320.1 - 9.2e-09 35.2 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.11 KII88321.1 - 5.8e-19 68.0 32.1 1.1e-14 53.9 14.0 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily Phage_connector PF05352.7 KII88321.1 - 0.22 10.6 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Phage Connector (GP10) Arf PF00025.16 KII88322.1 - 6.8e-68 227.3 0.0 7.6e-68 227.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KII88322.1 - 2e-10 39.9 0.2 3.6e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KII88322.1 - 2.1e-10 40.1 0.0 2.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KII88322.1 - 1.6e-07 31.8 0.0 2.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KII88322.1 - 3.8e-07 30.0 0.0 1.2e-06 28.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 KII88322.1 - 2e-06 27.2 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KII88322.1 - 7.2e-05 22.0 0.0 7.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KII88322.1 - 0.01 15.2 0.0 0.36 10.2 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KII88322.1 - 0.015 14.7 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 KII88322.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) Coa1 PF08695.5 KII88324.1 - 5e-34 116.2 0.0 7.3e-34 115.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 LSM14 PF12701.2 KII88325.1 - 7.8e-28 96.1 0.0 1.5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KII88325.1 - 2.1e-10 41.0 4.4 2.1e-10 41.0 3.0 1.9 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KII88325.1 - 0.00074 19.3 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain SWI-SNF_Ssr4 PF08549.5 KII88325.1 - 0.032 12.5 4.3 0.048 11.9 3.0 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) U79_P34 PF03064.11 KII88325.1 - 1.8 7.9 5.6 3.2 7.2 3.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Adenylsucc_synt PF00709.16 KII88327.1 - 4.6e-159 529.6 0.0 5.2e-159 529.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.1 KII88328.1 - 3.1e-28 97.7 0.1 4e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Clathrin PF00637.15 KII88329.1 - 3e-13 49.5 1.2 2.1e-08 33.8 1.7 3.3 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KII88329.1 - 2.6e-06 27.1 0.1 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 KII88329.1 - 0.16 11.8 8.6 0.29 10.9 6.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 KII88329.1 - 0.23 11.2 8.4 0.39 10.4 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII88329.1 - 0.37 10.8 7.8 0.67 10.0 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KII88329.1 - 0.74 9.6 2.5 1.5 8.6 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ATP-synt_J PF04911.7 KII88330.1 - 1.3e-22 78.9 0.4 1.4e-22 78.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain SWIM PF04434.12 KII88331.1 - 4.9e-07 29.0 0.2 1e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.1 KII88331.1 - 8.6e-06 25.4 7.7 8.6e-06 25.4 5.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII88331.1 - 0.0039 17.1 7.6 0.012 15.6 5.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KII88331.1 - 0.0061 16.4 4.7 0.0061 16.4 3.3 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain RINGv PF12906.2 KII88331.1 - 0.0073 16.3 6.9 0.0073 16.3 4.8 1.8 2 0 0 2 2 2 1 RING-variant domain zf-C3HC4_3 PF13920.1 KII88331.1 - 0.013 15.1 5.6 0.013 15.1 3.9 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII88331.1 - 0.02 14.9 5.5 0.02 14.9 3.8 1.9 2 1 0 2 2 2 0 RING-H2 zinc finger PHD PF00628.24 KII88331.1 - 0.065 12.9 6.9 0.15 11.8 4.8 1.6 1 0 0 1 1 1 0 PHD-finger NOB1_Zn_bind PF08772.6 KII88331.1 - 0.18 11.6 2.2 0.4 10.5 0.8 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Prok-RING_1 PF14446.1 KII88331.1 - 0.76 9.5 5.1 0.32 10.7 1.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 KII88331.1 - 1 9.2 10.7 0.11 12.3 3.7 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 KII88331.1 - 8.1 6.2 12.5 0.052 13.2 1.6 2.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KII88331.1 - 8.7 6.4 12.1 0.25 11.3 2.7 2.5 3 0 0 3 3 2 0 RING-like domain Prenyltransf PF01255.14 KII88332.1 - 1.3e-78 263.1 0.0 1.6e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Prenyltransf PF01255.14 KII88333.1 - 2.7e-79 265.3 0.0 3.2e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rab5ip PF07019.7 KII88333.1 - 0.079 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) TrbL PF04610.9 KII88335.1 - 0.3 10.7 10.5 0.13 11.8 4.7 2.0 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein PspC PF04024.7 KII88335.1 - 6.5 6.3 9.6 39 3.8 0.0 2.6 2 1 0 2 2 2 0 PspC domain MFS_1 PF07690.11 KII88336.1 - 4e-21 75.1 29.3 5.9e-16 58.1 12.8 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Ribosomal_L3 PF00297.17 KII88337.1 - 8.8e-39 133.4 2.7 2.6e-37 128.6 1.9 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Mito_carr PF00153.22 KII88338.1 - 5.2e-43 144.6 0.2 6.6e-14 51.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.4 KII88338.1 - 4.1e-16 58.2 1.7 4.7e-06 25.0 0.3 3.1 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor DIOX_N PF14226.1 KII88339.1 - 3e-23 82.5 0.0 4.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII88339.1 - 4.1e-20 71.9 0.0 6.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UFD1 PF03152.9 KII88340.1 - 2.2e-66 222.3 0.0 3.2e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KII88340.1 - 0.034 13.7 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Cpn60_TCP1 PF00118.19 KII88341.1 - 1e-142 476.2 10.9 1.2e-142 476.0 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3599 PF12206.3 KII88341.1 - 0.027 14.7 0.2 0.061 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) Vps52 PF04129.7 KII88341.1 - 0.034 12.6 0.3 0.061 11.8 0.2 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family Fungal_trans PF04082.13 KII88342.1 - 7.1e-32 110.2 0.4 1e-31 109.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KII88342.1 - 3.9e-08 33.1 9.2 0.00032 20.8 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII88342.1 - 1.4e-07 31.3 8.3 0.00072 19.7 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KII88342.1 - 0.26 10.9 6.2 0.12 12.0 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KII88342.1 - 0.51 10.5 2.0 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NMT PF01233.14 KII88343.1 - 7e-76 253.3 0.0 1.1e-75 252.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KII88343.1 - 9.5e-71 237.1 0.0 4.3e-70 234.9 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KII88343.1 - 1.4e-06 28.1 0.0 1.4e-05 24.9 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII88343.1 - 0.0014 18.7 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII88343.1 - 0.0093 15.9 0.0 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family ThiF PF00899.16 KII88344.1 - 5.3e-39 133.1 0.0 1.5e-38 131.6 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KII88344.1 - 1.8e-26 91.6 0.1 3e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KII88344.1 - 3.3e-24 84.2 0.5 5.7e-24 83.4 0.3 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KII88344.1 - 7.3e-18 63.6 1.2 1.6e-17 62.6 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KII88344.1 - 0.0014 18.1 0.7 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KII88344.1 - 0.0028 17.7 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KII88344.1 - 0.071 13.5 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_C PF09358.5 KII88344.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain ApbA PF02558.11 KII88344.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KII88344.1 - 0.18 10.6 0.2 0.37 9.6 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ecm33 PF12454.3 KII88344.1 - 0.19 11.6 2.8 0.4 10.6 1.9 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RTC PF01137.16 KII88345.1 - 4.3e-67 225.2 0.0 5e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KII88345.1 - 5e-29 100.3 0.0 7.8e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NPR2 PF06218.6 KII88346.1 - 1.9e-103 346.4 0.0 8.2e-88 294.9 0.0 2.5 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 KII88346.1 - 0.04 12.4 0.9 1.4 7.3 0.2 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 OGG_N PF07934.7 KII88347.1 - 4.6e-29 100.7 0.0 8.3e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KII88347.1 - 1.2e-14 54.5 0.0 2.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-CCCH PF00642.19 KII88348.1 - 0.00024 20.7 2.1 0.00065 19.3 1.4 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII88348.1 - 0.00051 19.9 1.7 0.0013 18.6 1.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type RRM_1 PF00076.17 KII88348.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulf_transp PF04143.9 KII88349.1 - 3.3e-17 62.2 19.5 1.8e-11 43.9 4.9 3.9 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 KII88349.1 - 9.1e-11 41.2 7.0 9.1e-11 41.2 4.8 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4341) DUF726 PF05277.7 KII88350.1 - 2.6e-82 276.4 6.6 3.6e-82 276.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KII88350.1 - 0.00082 19.3 2.7 0.0015 18.4 0.5 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII88350.1 - 0.25 11.1 0.1 0.25 11.1 0.0 2.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Pkinase_Tyr PF07714.12 KII88351.1 - 1.7e-40 138.7 0.0 1.9e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII88351.1 - 3.7e-38 131.1 0.0 4.5e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII88351.1 - 0.00021 20.3 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII88351.1 - 0.00069 18.7 0.1 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII88351.1 - 0.013 15.2 2.7 0.019 14.6 0.2 2.4 1 1 2 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KII88351.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KII88351.1 - 0.062 12.6 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GMC_oxred_N PF00732.14 KII88352.1 - 9.9e-61 205.4 0.0 1.5e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII88352.1 - 2.4e-36 125.1 0.0 4.4e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KII88352.1 - 8.8e-06 24.8 0.1 0.012 14.4 0.0 3.2 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 KII88352.1 - 0.00024 20.1 0.0 0.0092 14.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII88352.1 - 0.0018 18.2 0.1 0.0064 16.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII88352.1 - 0.003 16.5 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KII88352.1 - 0.019 15.0 0.8 0.53 10.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LEA_2 PF03168.8 KII88353.1 - 4.7e-08 33.3 0.2 7.5e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 KII88353.1 - 2.2e-05 23.7 0.1 3.1e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.2 KII88353.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 JmjC PF02373.17 KII88355.1 - 1.7e-13 50.7 0.0 3.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 KII88355.1 - 0.037 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Pkinase PF00069.20 KII88356.1 - 2.8e-36 125.0 0.0 3.5e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88356.1 - 6.6e-13 48.3 0.0 9.5e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII88356.1 - 0.00049 19.9 0.3 0.66 9.6 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Ras PF00071.17 KII88357.1 - 2.5e-50 170.0 0.0 3e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII88357.1 - 2.3e-16 60.3 0.0 3.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII88357.1 - 3.1e-10 39.5 0.0 4.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII88357.1 - 8.4e-05 21.8 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KII88357.1 - 0.0071 15.0 1.8 1.3 7.6 0.1 2.6 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 KII88357.1 - 0.014 15.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 KII88357.1 - 0.03 13.5 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KII88357.1 - 0.043 13.9 0.1 0.1 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII88357.1 - 0.085 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 KII88357.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain MMR_HSR1 PF01926.18 KII88357.1 - 0.15 12.0 0.2 0.3 11.0 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.11 KII88358.1 - 2.5e-48 164.5 40.9 2.5e-48 164.5 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KII88358.1 - 1.4e-19 69.8 17.0 1.9e-19 69.3 11.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KII88358.1 - 2.7e-13 49.2 8.0 2.7e-13 49.2 5.6 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Neurensin PF14927.1 KII88358.1 - 0.38 10.1 3.6 1.3 8.3 2.5 1.7 1 1 0 1 1 1 0 Neurensin Vac_ImportDeg PF09783.4 KII88359.1 - 2.7e-57 193.0 0.1 7.5e-52 175.3 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein Pyr_redox_3 PF13738.1 KII88360.1 - 6.8e-25 88.3 0.0 6.9e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII88360.1 - 1.8e-11 42.9 0.1 9e-11 40.6 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KII88360.1 - 3.5e-10 39.3 0.0 8.3e-08 31.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KII88360.1 - 3.8e-09 36.4 0.0 9.6e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII88360.1 - 2.6e-07 30.7 0.0 1.3e-05 25.1 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII88360.1 - 0.00057 18.8 0.0 0.011 14.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII88360.1 - 0.0015 18.2 0.5 0.045 13.5 0.1 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Semialdhyde_dh PF01118.19 KII88360.1 - 0.036 14.3 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GIDA PF01134.17 KII88360.1 - 0.065 12.0 0.1 22 3.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A He_PIG PF05345.7 KII88362.1 - 0.005 16.8 0.2 0.058 13.4 0.0 2.7 2 0 0 2 2 2 1 Putative Ig domain LUC7 PF03194.10 KII88365.1 - 1.3e-71 241.0 3.4 1.8e-71 240.6 2.4 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Ada3 PF10198.4 KII88365.1 - 0.0054 16.4 0.6 0.011 15.4 0.4 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Atg14 PF10186.4 KII88365.1 - 0.016 14.1 0.7 0.026 13.4 0.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_D PF01813.12 KII88366.1 - 6.5e-65 218.3 3.2 6.5e-65 218.3 2.2 1.6 2 0 0 2 2 2 1 ATP synthase subunit D PriCT_1 PF08708.6 KII88366.1 - 0.052 13.3 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) ISG65-75 PF11727.3 KII88366.1 - 0.6 9.1 3.7 0.3 10.0 0.4 1.8 2 0 0 2 2 2 0 Invariant surface glycoprotein KOW PF00467.24 KII88367.1 - 1.4e-09 37.2 3.5 1.4e-09 37.2 2.4 2.1 2 0 0 2 2 2 1 KOW motif FRG1 PF06229.7 KII88368.1 - 4e-25 88.3 0.1 7.3e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KII88368.1 - 0.00098 19.2 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Fascin domain DUF1754 PF08555.5 KII88368.1 - 0.056 14.0 15.0 0.2 12.2 1.2 2.5 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) UCH PF00443.24 KII88369.1 - 4.3e-41 140.8 0.5 8.5e-41 139.8 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII88369.1 - 5.4e-23 81.8 1.3 9.4e-23 81.0 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KII88369.1 - 0.00013 21.2 0.1 0.00031 20.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.7 KII88369.1 - 0.037 14.4 0.1 0.61 10.5 0.0 2.7 1 1 0 1 1 1 0 DUSP domain zf-RanBP PF00641.13 KII88369.1 - 0.084 11.9 8.8 0.021 13.9 2.1 3.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Gaa1 PF04114.9 KII88370.1 - 4.8e-71 239.9 3.1 9.9e-37 126.7 0.0 2.1 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component DUF3357 PF11837.3 KII88370.1 - 0.073 12.9 0.1 0.35 10.7 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TAFII55_N PF04658.8 KII88371.1 - 6.1e-57 191.6 0.9 1.3e-56 190.5 0.6 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region DnaJ PF00226.26 KII88372.1 - 4.4e-16 58.3 0.1 1.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.2 KII88372.1 - 3.6e-13 49.6 0.0 1e-11 45.0 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KII88372.1 - 3e-10 39.3 0.0 0.0016 18.1 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KII88372.1 - 3.3e-10 40.2 0.0 8.2e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII88372.1 - 1.7e-09 37.0 0.0 0.0098 16.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KII88372.1 - 3.5e-08 33.4 0.0 0.0029 17.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Borrelia_P83 PF05262.6 KII88372.1 - 0.78 7.9 12.3 1.1 7.4 8.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 KII88372.1 - 1.3 8.9 11.9 0.12 12.2 4.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BCS1_N PF08740.6 KII88373.1 - 3.1e-50 170.3 1.2 4.1e-50 169.9 0.8 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KII88373.1 - 1.3e-17 64.2 0.0 2.3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KII88373.1 - 5.7e-05 23.9 0.0 0.00012 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII88373.1 - 0.00012 21.5 0.0 0.00068 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KII88373.1 - 0.00039 20.2 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII88373.1 - 0.00088 19.3 0.3 0.003 17.5 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KII88373.1 - 0.00095 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KII88373.1 - 0.004 16.6 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KII88373.1 - 0.01 15.9 0.0 0.042 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KII88373.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KII88373.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 KII88373.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KII88373.1 - 0.044 14.0 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 KII88373.1 - 0.059 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KII88373.1 - 0.059 13.6 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KII88373.1 - 0.06 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KII88373.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KII88373.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.14 KII88373.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 KII88373.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KII88373.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain WBS_methylT PF12589.3 KII88374.1 - 1.2e-18 67.3 6.7 1.2e-18 67.3 4.6 1.5 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KII88374.1 - 8.8e-09 35.7 0.0 1.9e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII88374.1 - 3e-06 27.0 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII88374.1 - 0.00012 22.4 0.0 0.0005 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII88374.1 - 0.00051 19.6 0.0 0.00096 18.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII88374.1 - 0.0013 19.3 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII88374.1 - 0.012 15.9 0.0 0.036 14.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.8 KII88374.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.11 KII88375.1 - 1.1e-33 115.8 0.0 1.6e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PTP_N PF12453.3 KII88375.1 - 0.033 13.7 1.0 0.062 12.9 0.7 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal C_GCAxxG_C_C PF09719.5 KII88375.1 - 0.08 12.7 0.0 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Exo_endo_phos PF03372.18 KII88376.1 - 1.7e-19 70.7 0.1 7.3e-19 68.6 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KII88376.1 - 7.4e-06 25.5 0.1 0.063 12.8 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Pec_lyase_C PF00544.14 KII88379.1 - 0.0026 17.2 2.6 0.0026 17.2 1.8 2.0 2 0 0 2 2 2 1 Pectate lyase Tom37 PF10568.4 KII88380.1 - 1.1e-11 44.8 0.1 1.8e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 KII88380.1 - 5.4e-10 39.3 0.0 1.6e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Tom37 C-terminal domain GST_C_2 PF13410.1 KII88380.1 - 4e-06 26.6 0.0 9.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII88380.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII88380.1 - 0.014 15.3 0.0 0.072 13.0 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain XAP5 PF04921.9 KII88381.1 - 1.5e-94 316.0 4.3 1.5e-94 316.0 3.0 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator Cnd1_N PF12922.2 KII88381.1 - 0.15 11.6 2.2 0.24 11.0 1.5 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term NST1 PF13945.1 KII88381.1 - 0.67 9.9 15.8 0.031 14.3 7.0 1.6 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF4618 PF15397.1 KII88381.1 - 0.81 8.9 13.7 0.039 13.2 5.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Ribosomal_S13 PF00416.17 KII88382.1 - 5.2e-25 87.9 0.0 1e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KII88382.1 - 3.5e-05 22.5 0.1 6.1e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.3 KII88382.1 - 0.0027 17.6 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif OTU PF02338.14 KII88383.1 - 2.1e-11 44.4 0.0 3.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.18 KII88383.1 - 0.015 14.7 0.3 0.099 12.0 0.2 2.2 1 1 0 1 1 1 0 Ubiquitin family SecY PF00344.15 KII88383.1 - 0.23 10.3 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 SecY translocase Acyl-CoA_dh_1 PF00441.19 KII88384.1 - 2.6e-30 105.5 0.4 4.6e-30 104.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII88384.1 - 3e-16 58.6 1.2 7.1e-16 57.4 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KII88384.1 - 2.7e-15 55.9 0.1 7.8e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KII88384.1 - 2.5e-11 44.1 0.0 1.2e-10 41.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KII88384.1 - 3.4e-06 27.3 0.1 8.2e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KII88385.1 - 7.7e-31 107.2 0.4 1.3e-30 106.4 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII88385.1 - 5.4e-16 57.8 0.9 1.3e-15 56.6 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KII88385.1 - 2.4e-15 56.0 0.0 1.6e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KII88385.1 - 4.7e-12 46.4 0.0 4.9e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KII88385.1 - 2.3e-06 27.9 0.1 4.8e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.17 KII88386.1 - 2.8e-60 204.1 0.0 3.4e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII88387.1 - 0.066 11.7 0.0 0.083 11.3 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 UCR_hinge PF02320.11 KII88388.1 - 2.8e-14 52.7 11.1 3.1e-08 33.4 4.7 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein C8 PF08742.6 KII88388.1 - 0.037 14.2 4.2 0.076 13.2 2.9 1.5 1 0 0 1 1 1 0 C8 domain OAD_gamma PF04277.8 KII88388.1 - 0.062 13.6 1.7 0.091 13.1 1.2 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Sigma70_ner PF04546.8 KII88388.1 - 0.11 12.1 3.2 0.11 12.0 2.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3530 PF12048.3 KII88388.1 - 0.95 8.3 3.6 1 8.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3306 PF11748.3 KII88388.1 - 1.4 9.5 5.6 1.9 9.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RR_TM4-6 PF06459.7 KII88388.1 - 1.6 8.5 7.1 1.9 8.3 4.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BEX PF04538.7 KII88388.1 - 2.6 8.2 9.7 3.7 7.8 6.7 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family Trypan_PARP PF05887.6 KII88388.1 - 7.7 6.3 19.2 15 5.4 13.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.17 KII88389.1 - 3e-54 184.2 0.0 4.1e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 KII88390.1 - 1.3e-65 221.1 0.0 1.9e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KII88390.1 - 5.8e-40 137.1 9.3 1.1e-39 136.2 6.5 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 KII88390.1 - 6e-13 48.4 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KII88390.1 - 4.4e-06 25.7 0.0 1.4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KII88390.1 - 0.0052 16.9 0.1 0.082 13.0 0.0 2.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 KII88390.1 - 0.031 14.0 0.0 0.2 11.4 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit U1snRNP70_N PF12220.3 KII88390.1 - 1 9.7 6.0 0.24 11.7 0.8 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pkinase PF00069.20 KII88391.1 - 4.4e-56 189.8 0.0 5.2e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88391.1 - 3.3e-41 141.0 0.0 4.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII88391.1 - 0.00024 20.1 0.0 0.0071 15.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like PQ-loop PF04193.9 KII88392.1 - 2e-38 129.7 8.0 9e-19 66.7 2.0 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KII88392.1 - 0.0077 16.0 0.4 0.029 14.2 0.3 1.9 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange GYF PF02213.11 KII88393.1 - 4.4e-06 26.1 0.2 7.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 GYF domain NAD_binding_10 PF13460.1 KII88394.1 - 1.4e-12 47.9 0.1 1.6e-10 41.3 0.1 2.7 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KII88394.1 - 3.7e-11 42.9 0.3 8.7e-07 28.6 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII88394.1 - 0.00089 18.0 0.0 0.01 14.5 0.0 2.3 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KII88394.1 - 0.0065 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KII88394.1 - 0.14 11.0 0.0 0.94 8.3 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein ADK PF00406.17 KII88395.1 - 2.9e-44 150.5 0.0 3.8e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KII88395.1 - 1.2e-12 47.2 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KII88395.1 - 4.8e-07 30.6 0.0 7.2e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII88395.1 - 1.6e-06 28.0 0.0 1.6e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KII88395.1 - 3.7e-05 24.0 0.0 8.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KII88395.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 KII88395.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Methyltransf_PK PF05891.7 KII88396.1 - 1.1e-52 178.5 0.0 1.5e-32 112.6 0.0 2.3 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KII88396.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII88396.1 - 0.00045 20.7 0.1 0.0016 19.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII88396.1 - 0.00097 19.5 0.0 0.015 15.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII88396.1 - 0.0035 17.6 0.0 0.0099 16.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII88396.1 - 0.0039 17.6 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain RPA_C PF08784.6 KII88398.1 - 5.8e-17 61.9 0.9 1.1e-16 61.0 0.2 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KII88398.1 - 1.6e-06 27.8 0.9 2.8e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_27 PF13463.1 KII88398.1 - 5.1e-05 23.5 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.2 KII88398.1 - 0.0015 18.1 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 KII88398.1 - 0.0018 18.0 0.0 0.0064 16.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.16 KII88398.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family CMD PF02627.15 KII88398.1 - 0.045 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Fe_dep_repress PF01325.14 KII88398.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Prenyltrans_2 PF13249.1 KII88398.1 - 0.065 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Prenyltransferase-like MarR PF01047.17 KII88398.1 - 0.077 12.7 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 MarR family NTF2 PF02136.15 KII88398.1 - 0.078 13.3 0.1 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain NatB_MDM20 PF09797.4 KII88399.1 - 1.3e-69 234.7 1.3 2.3e-69 233.8 0.9 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 KII88399.1 - 3.8e-07 30.1 0.1 0.0073 16.8 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KII88399.1 - 4.9e-06 26.9 0.5 5.2e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_19 PF14559.1 KII88399.1 - 9.2e-06 25.9 0.0 4.1 7.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.1 KII88399.1 - 0.0096 15.0 2.7 0.098 11.7 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII88399.1 - 0.012 16.2 0.0 65 4.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KII88399.1 - 0.16 11.9 1.2 13 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2665 PF11654.3 KII88400.1 - 1.3e-15 56.7 0.1 1.5e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Hydrolase PF00702.21 KII88401.1 - 1.3e-12 48.6 0.1 3.6e-12 47.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KII88401.1 - 7.8e-12 45.7 0.0 3.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII88401.1 - 3.3e-06 26.7 0.0 8.8e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KII88401.1 - 0.00061 20.0 0.0 0.0013 18.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Med16 PF11635.3 KII88403.1 - 5.9e-07 27.8 0.2 3.8e-06 25.1 0.1 1.9 1 1 0 1 1 1 1 Mediator complex subunit 16 SHOCT PF09851.4 KII88404.1 - 0.008 15.6 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Short C-terminal domain Condensation PF00668.15 KII88404.1 - 0.0091 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PNTB PF02233.11 KII88405.1 - 1.6e-170 567.8 22.1 1.6e-170 567.8 15.3 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KII88405.1 - 4.3e-52 176.0 0.5 8.4e-52 175.1 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KII88405.1 - 9.9e-45 151.8 0.1 2.5e-44 150.5 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KII88405.1 - 2.8e-32 110.7 3.0 2.8e-32 110.7 2.1 5.1 4 2 1 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KII88405.1 - 0.0053 15.9 2.7 3.2 6.8 0.0 4.2 3 1 1 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KII88405.1 - 0.029 14.2 0.2 0.076 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII88405.1 - 2.3 8.2 8.4 0.58 10.2 0.6 3.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KII88405.1 - 3.5 7.7 10.8 1.1 9.3 0.1 3.9 4 1 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase DHDPS PF00701.17 KII88406.1 - 5.1e-28 97.5 0.0 2.5e-27 95.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Transp_Tc5_C PF04236.10 KII88407.1 - 0.039 14.1 0.2 0.062 13.5 0.2 1.3 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-AN1 PF01428.11 KII88407.1 - 0.15 11.9 1.0 0.2 11.5 0.2 1.5 2 0 0 2 2 2 0 AN1-like Zinc finger TruB_N PF01509.13 KII88408.1 - 1.4e-45 155.1 0.0 4.8e-45 153.3 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Cu_bind_like PF02298.12 KII88409.1 - 7.8e-06 25.6 5.9 0.074 12.8 0.3 4.0 2 2 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.15 KII88409.1 - 0.00028 21.0 0.9 1.1 9.4 0.1 3.1 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 KII88409.1 - 0.00079 19.2 0.0 0.076 12.9 0.0 2.7 2 0 0 2 2 2 1 Cupredoxin-like domain MFS_1 PF07690.11 KII88410.1 - 5.2e-26 91.1 35.6 1.7e-14 53.3 17.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_sug_transp PF04142.10 KII88411.1 - 5.4e-79 264.7 14.9 8.3e-79 264.1 10.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KII88411.1 - 8.5e-09 34.7 13.9 1.2e-08 34.2 9.7 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KII88411.1 - 2.7e-07 30.7 21.0 6.1e-07 29.6 1.8 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 KII88411.1 - 1.8e-06 28.0 27.2 2e-06 27.8 2.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KII88411.1 - 6e-05 22.7 28.6 0.0001 22.0 2.4 2.8 2 2 0 2 2 2 2 Triose-phosphate Transporter family BRCT PF00533.21 KII88413.1 - 1.7e-05 24.8 1.1 0.0002 21.4 0.1 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.1 KII88413.1 - 2.6e-05 23.9 0.0 6.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.5 KII88413.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor Rad9_Rad53_bind PF08605.5 KII88413.1 - 0.0002 21.1 0.0 0.0021 17.8 0.0 2.1 1 1 1 2 2 2 1 Fungal Rad9-like Rad53-binding DUF1325 PF07039.6 KII88413.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF2367 PF10164.4 KII88414.1 - 1.6e-06 27.8 2.9 2e-06 27.5 2.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.4 KII88414.1 - 0.0014 18.4 0.9 0.0021 17.8 0.6 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-CCHC_5 PF14787.1 KII88414.1 - 0.12 11.8 1.7 6.7 6.2 0.0 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger ATP1G1_PLM_MAT8 PF02038.11 KII88414.1 - 0.23 10.5 2.6 0.38 9.8 1.8 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family zf-HIT PF04438.11 KII88414.1 - 0.6 9.8 4.2 0.52 10.0 1.5 2.0 1 1 0 1 1 1 0 HIT zinc finger zf-C2HC5 PF06221.8 KII88414.1 - 0.75 9.5 6.0 1.2 8.9 3.9 1.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Chromo PF00385.19 KII88415.1 - 4.2e-11 42.3 2.8 7.1e-11 41.6 2.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Snf7 PF03357.16 KII88416.1 - 7.1e-18 64.5 7.2 1.1e-17 64.0 5.0 1.2 1 0 0 1 1 1 1 Snf7 DUF1378 PF07125.6 KII88416.1 - 0.083 12.8 0.0 0.34 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Aldo_ket_red PF00248.16 KII88417.1 - 8.9e-40 136.2 0.0 1.2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SKG6 PF08693.5 KII88418.1 - 0.00036 19.7 2.4 0.00036 19.7 1.7 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KII88418.1 - 0.0075 14.5 0.0 0.0075 14.5 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E RCR PF12273.3 KII88418.1 - 0.021 15.3 4.2 0.17 12.4 2.9 2.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Gly-zipper_OmpA PF13436.1 KII88418.1 - 0.044 13.4 4.6 0.13 11.9 3.2 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Beta-APP PF03494.8 KII88418.1 - 0.14 11.6 4.6 0.25 10.8 3.2 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Syndecan PF01034.15 KII88418.1 - 0.22 11.2 0.3 0.5 10.0 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Bacteriocin_IIc PF10439.4 KII88418.1 - 0.35 11.0 4.7 1.2 9.3 3.3 1.9 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF4229 PF14012.1 KII88418.1 - 0.97 9.3 5.8 0.42 10.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Ribosomal_L30_N PF08079.7 KII88419.1 - 1.5e-26 92.2 16.2 2.8e-26 91.3 11.3 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KII88419.1 - 1.5e-19 69.2 1.6 3e-19 68.3 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CLTH PF10607.4 KII88421.1 - 1.8e-19 69.8 0.0 2.7e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KII88421.1 - 2.3e-06 27.1 0.0 6.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 LisH DAO PF01266.19 KII88422.1 - 3.5e-47 161.0 0.2 4.1e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII88422.1 - 0.00052 19.9 0.2 0.063 13.1 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII88422.1 - 0.0024 16.7 0.1 0.67 8.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A F420_oxidored PF03807.12 KII88422.1 - 0.0042 17.4 0.2 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KII88422.1 - 0.0053 16.5 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 ThiF family NAD_binding_9 PF13454.1 KII88422.1 - 0.0091 15.7 0.3 0.77 9.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KII88422.1 - 0.052 13.5 0.5 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 KII88422.1 - 0.053 13.4 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_3 PF13738.1 KII88422.1 - 0.053 13.5 0.0 4.3 7.3 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 KII88422.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KII88422.1 - 0.096 12.3 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 KII88422.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 KR domain SRP54 PF00448.17 KII88423.1 - 1.8e-73 246.1 0.6 4e-73 245.0 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KII88423.1 - 3.3e-22 78.7 0.2 3.3e-22 78.7 0.1 4.1 2 2 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 KII88423.1 - 4.1e-14 52.4 5.8 9.2e-14 51.3 4.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 KII88423.1 - 1.8e-06 27.9 0.1 3.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KII88423.1 - 3.1e-06 26.7 0.3 8.4e-06 25.3 0.2 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KII88423.1 - 0.0012 17.9 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 KII88423.1 - 0.0015 18.2 0.1 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KII88423.1 - 0.0021 16.9 0.6 0.009 14.8 0.1 2.3 2 1 0 2 2 2 1 ArgK protein CbiA PF01656.18 KII88423.1 - 0.0033 16.8 0.3 0.02 14.3 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KII88423.1 - 0.027 15.3 0.0 0.057 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1768 PF08719.6 KII88423.1 - 0.067 12.9 0.6 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) AAA_31 PF13614.1 KII88423.1 - 0.069 13.0 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KII88423.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KII88423.1 - 0.11 11.0 1.4 0.95 8.0 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF2201 PF09967.4 KII88423.1 - 0.22 11.5 1.8 0.6 10.1 0.1 2.6 2 1 1 3 3 3 0 VWA-like domain (DUF2201) WD40 PF00400.27 KII88424.1 - 1.5e-17 62.7 20.0 0.0027 17.5 0.0 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Methyltransf_23 PF13489.1 KII88425.1 - 3.6e-16 59.2 0.0 5.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII88425.1 - 6.9e-11 41.9 0.0 5e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII88425.1 - 1.9e-10 41.0 0.0 3.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KII88425.1 - 7.3e-07 27.8 0.0 2.3e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 KII88425.1 - 1.1e-06 29.2 0.0 6.3e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII88425.1 - 2.9e-06 27.6 0.0 8.9e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KII88425.1 - 3.8e-06 26.6 0.0 7.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 KII88425.1 - 1.4e-05 25.4 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII88425.1 - 7.7e-05 21.8 0.0 0.0034 16.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 KII88425.1 - 0.0002 20.5 0.0 0.0033 16.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KII88425.1 - 0.00026 20.4 0.0 0.00083 18.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KII88425.1 - 0.00055 19.1 0.0 0.0084 15.3 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_8 PF05148.10 KII88425.1 - 0.0038 16.9 0.0 0.0082 15.8 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 KII88425.1 - 0.0082 15.2 0.0 0.072 12.1 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KII88425.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KII88425.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 KII88425.1 - 0.049 12.7 0.0 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G RRM_1 PF00076.17 KII88426.1 - 6.6e-84 275.5 2.7 2.4e-21 75.1 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII88426.1 - 3.5e-54 180.6 0.7 7.7e-15 54.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII88426.1 - 1.9e-42 142.9 0.1 1.7e-12 46.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KII88426.1 - 5.3e-27 93.3 0.9 1.4e-26 91.9 0.7 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 KII88426.1 - 1.9e-05 24.4 5.4 0.02 14.7 0.3 3.6 4 0 0 4 4 4 1 RNA binding motif Limkain-b1 PF11608.3 KII88426.1 - 0.00019 21.1 2.2 0.075 12.7 0.1 3.5 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.6 KII88426.1 - 0.00075 18.9 0.8 5.6 6.5 0.1 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KII88426.1 - 0.0019 17.9 0.1 8.4 6.2 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KII88426.1 - 0.015 15.4 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis central region DUF4407 PF14362.1 KII88426.1 - 0.13 11.2 0.7 0.25 10.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SCAMP PF04144.8 KII88427.1 - 8.5e-47 159.3 4.3 9.9e-47 159.0 3.0 1.0 1 0 0 1 1 1 1 SCAMP family DPBB_1 PF03330.13 KII88428.1 - 3e-11 43.1 0.2 7.5e-11 41.8 0.2 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII88428.1 - 8.7e-06 25.4 0.3 1.7e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Barwin family DUF4551 PF15087.1 KII88428.1 - 2 6.6 7.9 2.6 6.2 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF572 PF04502.8 KII88428.1 - 2.3 7.3 7.7 3.3 6.8 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3948 PF13134.1 KII88430.1 - 0.017 14.5 3.1 0.44 10.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Cytochrom_B_N PF00033.14 KII88430.1 - 0.78 9.0 5.0 2.7 7.3 3.5 1.8 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF202 PF02656.10 KII88430.1 - 2.9 8.1 12.4 0.96 9.7 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SH2_2 PF14633.1 KII88431.1 - 3.4e-69 232.2 1.6 6e-69 231.4 0.3 2.0 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KII88431.1 - 1.3e-30 105.7 2.3 1.3e-30 105.7 1.6 3.4 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 KII88431.1 - 3.6e-30 104.1 0.0 7.5e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KII88431.1 - 1.8e-28 98.9 1.9 6.4e-17 61.5 0.0 3.1 3 0 0 3 3 3 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KII88431.1 - 1.4e-19 69.9 29.6 1.4e-19 69.9 20.5 5.9 5 1 1 6 6 6 2 Acidic N-terminal SPT6 HTH_44 PF14641.1 KII88431.1 - 9.8e-16 57.8 0.1 3.2e-15 56.1 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KII88431.1 - 9.1e-07 28.6 0.0 7.8e-06 25.6 0.0 2.5 2 0 0 2 2 2 1 SH2 domain S1 PF00575.18 KII88431.1 - 1.2e-05 25.3 2.5 2.1e-05 24.5 1.0 2.0 2 0 0 2 2 2 1 S1 RNA binding domain HHH_3 PF12836.2 KII88431.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif dCMP_cyt_deam_1 PF00383.17 KII88432.1 - 3e-13 49.2 0.0 5.9e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF3670 PF12419.3 KII88432.1 - 0.059 12.7 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 SNF2 Helicase protein Ribosomal_L24e PF01246.15 KII88435.1 - 1.9e-30 104.5 3.3 3.5e-30 103.6 2.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 KII88435.1 - 0.065 12.8 5.1 0.13 11.9 3.6 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATG_C PF09333.6 KII88436.1 - 4.3e-33 113.3 0.1 8.5e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KII88436.1 - 3.7e-09 36.1 0.0 8.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ANF_receptor PF01094.23 KII88436.1 - 0.024 13.4 0.2 0.047 12.4 0.1 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region ATG2_CAD PF13329.1 KII88436.1 - 0.045 13.3 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif Lipase_GDSL_2 PF13472.1 KII88437.1 - 6.3e-08 32.9 0.1 8.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII88437.1 - 2.8e-05 24.0 0.0 6.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Swi3 PF07962.7 KII88438.1 - 2.7e-25 87.7 0.1 4.3e-25 87.1 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DPBB_1 PF03330.13 KII88439.1 - 2.5e-08 33.7 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel HTH_17 PF12728.2 KII88440.1 - 0.002 18.3 0.1 0.0027 17.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain WD40 PF00400.27 KII88441.1 - 1.6e-09 37.2 18.3 0.00037 20.2 0.8 5.3 7 0 0 7 7 7 3 WD domain, G-beta repeat U79_P34 PF03064.11 KII88441.1 - 0.32 10.4 5.9 4.5 6.7 4.5 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 AA_permease_2 PF13520.1 KII88442.1 - 8.7e-86 288.1 41.9 1e-85 287.8 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII88442.1 - 7.5e-17 60.8 32.3 7.5e-17 60.8 22.4 2.1 2 1 0 2 2 2 1 Amino acid permease F-box-like PF12937.2 KII88443.1 - 0.00028 20.5 0.1 0.00082 19.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like PRNT PF15174.1 KII88443.1 - 0.023 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Prion-related protein testis-specific adh_short PF00106.20 KII88444.1 - 1e-10 41.7 0.1 1.9e-10 40.9 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII88444.1 - 7.7e-06 25.8 0.0 0.00013 21.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII88444.1 - 0.0033 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KII88444.1 - 0.053 12.4 0.1 0.17 10.8 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Mito_fiss_reg PF05308.6 KII88445.1 - 0.22 10.8 2.8 0.33 10.2 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SAP PF02037.22 KII88446.1 - 3.8e-10 39.0 0.1 6.8e-09 35.0 0.1 2.2 2 0 0 2 2 2 1 SAP domain DUF2315 PF10231.4 KII88447.1 - 1.6e-12 47.4 6.3 2.2e-11 43.7 2.7 2.2 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) MaoC_dehydratas PF01575.14 KII88448.1 - 0.011 15.1 0.1 0.058 12.7 0.0 2.0 2 0 0 2 2 2 0 MaoC like domain Histone PF00125.19 KII88449.1 - 1.7e-21 76.1 0.2 2.4e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII88449.1 - 5.5e-05 23.1 0.9 7.9e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KII88449.1 - 0.00017 21.7 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KII88449.1 - 0.04 14.4 0.5 0.053 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 KII88449.1 - 0.041 13.2 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein PRCC PF10253.4 KII88450.1 - 1.1e-29 104.4 3.7 1.1e-29 104.4 2.6 2.4 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF1785 PF08699.5 KII88451.1 - 0.013 14.8 1.4 29 4.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1785) Nitro_FeMo-Co PF02579.12 KII88451.1 - 5.8 7.0 10.3 1.8 8.7 0.1 3.8 3 1 0 4 4 4 0 Dinitrogenase iron-molybdenum cofactor Pkinase PF00069.20 KII88452.1 - 5e-29 101.2 0.0 9.3e-29 100.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88452.1 - 1.5e-09 37.3 0.0 0.00046 19.3 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 KII88452.1 - 0.00056 19.0 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleoporin_C PF03177.9 KII88453.1 - 8.9e-57 192.9 0.3 1.3e-56 192.3 0.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KII88453.1 - 8.2e-18 64.3 0.0 1.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Methyltransf_11 PF08241.7 KII88454.1 - 1.7e-12 47.6 0.0 3.8e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII88454.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII88454.1 - 2.2e-06 28.2 0.0 3.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII88454.1 - 2.4e-05 24.7 0.0 4.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII88454.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII88454.1 - 0.00088 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KII88454.1 - 0.056 12.8 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DAGK_cat PF00781.19 KII88455.1 - 3.5e-24 84.6 0.1 8.5e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Histone PF00125.19 KII88456.1 - 2.7e-22 78.6 0.2 4.1e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KII88456.1 - 3.7e-05 23.7 0.1 3.7e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KII88456.1 - 0.00043 20.5 0.0 0.00075 19.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KII88456.1 - 0.021 15.3 0.5 0.032 14.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 KII88456.1 - 0.054 12.9 0.1 0.095 12.1 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF3292 PF11696.3 KII88456.1 - 3.7 5.3 9.2 5.9 4.6 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2360 PF10152.4 KII88456.1 - 7.7 6.7 8.6 8.6 6.6 5.6 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 KII88457.1 - 7.3e-68 228.5 0.0 9.8e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88457.1 - 3.7e-46 157.2 0.0 5.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KII88457.1 - 3.9e-17 62.0 0.0 8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KII88457.1 - 2e-14 53.4 0.0 4.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KII88457.1 - 2.4e-12 46.5 0.0 5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KII88457.1 - 0.0005 19.1 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KII88457.1 - 0.27 10.0 0.0 0.46 9.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CDC45 PF02724.9 KII88457.1 - 1.5 6.7 6.3 2 6.3 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 KII88457.1 - 7.8 5.3 8.1 13 4.6 5.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RTC4 PF14474.1 KII88459.1 - 1.2e-19 70.5 0.0 2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Alpha-amylase PF00128.19 KII88464.1 - 2.8e-26 92.6 3.6 2.5e-23 82.9 1.0 3.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KII88464.1 - 2.8e-15 56.4 0.1 5.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KII88464.1 - 5.3e-09 36.3 0.1 1.6e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KII88464.1 - 5.4e-09 35.6 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 KII88464.1 - 0.065 13.8 3.2 0.098 13.2 0.7 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain TRM PF02005.11 KII88465.1 - 6.1e-120 400.5 0.0 8.4e-120 400.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KII88465.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KII88465.1 - 0.035 13.6 0.1 0.074 12.6 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.4 KII88465.1 - 0.094 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.2 KII88465.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TFIID-18kDa PF02269.11 KII88466.1 - 1.7e-19 69.3 0.0 2.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PAT1 PF09770.4 KII88466.1 - 0.24 9.6 15.5 0.22 9.7 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KII88466.1 - 4.7 6.9 7.6 4.9 6.9 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.17 KII88467.1 - 1.1e-16 60.2 0.1 2.4e-16 59.1 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII88467.1 - 3e-13 49.5 0.0 3.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII88467.1 - 3.4e-07 29.9 0.0 1.8e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KII88467.1 - 0.00026 20.6 0.1 0.00042 20.0 0.0 1.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KII88467.1 - 0.00081 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 KII88468.1 - 1.6e-12 47.1 0.0 2.9e-11 43.0 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88468.1 - 0.00046 19.3 0.0 0.00068 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII88468.1 - 0.0055 15.7 0.4 0.0095 15.0 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII88468.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2040 PF09745.4 KII88469.1 - 5.4e-32 110.3 23.3 5.4e-32 110.3 16.2 3.3 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RNase_PH PF01138.16 KII88470.1 - 5.7e-32 110.8 0.1 1.2e-31 109.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KII88470.1 - 0.00023 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AA_permease_2 PF13520.1 KII88471.1 - 7.3e-65 219.1 40.6 9.1e-65 218.8 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII88471.1 - 3.1e-33 114.8 35.5 7.2e-33 113.6 24.7 1.4 1 1 0 1 1 1 1 Amino acid permease HMA PF00403.21 KII88472.1 - 3.1e-14 52.8 0.9 3.8e-14 52.5 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain NAD_binding_6 PF08030.7 KII88473.1 - 8e-15 55.0 0.0 2.8e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KII88473.1 - 2.3e-14 53.5 14.7 2.3e-14 53.5 10.2 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KII88473.1 - 5.6e-14 51.8 0.0 2.6e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain DUF4211 PF13926.1 KII88474.1 - 3.8e-31 107.5 0.1 1.4e-30 105.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) C1_1 PF00130.17 KII88475.1 - 3e-08 33.2 3.2 3e-08 33.2 2.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 KII88475.1 - 0.00014 20.3 0.1 0.00045 18.7 0.0 1.8 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 PHD PF00628.24 KII88475.1 - 1.6 8.4 21.4 0.48 10.1 4.8 2.5 2 0 0 2 2 2 0 PHD-finger DPM2 PF07297.7 KII88476.1 - 7.3e-30 103.0 0.5 8.8e-30 102.8 0.3 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KII88476.1 - 6.1e-06 25.8 0.2 7.4e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 PIG-P TatC PF00902.13 KII88476.1 - 0.017 14.4 0.4 0.021 14.2 0.3 1.2 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Sensor PF13796.1 KII88476.1 - 0.022 14.3 0.7 0.027 14.0 0.5 1.1 1 0 0 1 1 1 0 Putative sensor TRAPPC9-Trs120 PF08626.6 KII88477.1 - 8.3e-113 377.8 0.0 1.3e-111 373.8 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps55 PF04133.9 KII88478.1 - 3e-42 143.1 4.2 3.4e-42 142.9 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 BCLP PF12304.3 KII88478.1 - 0.12 11.7 3.0 0.2 11.0 1.5 1.7 1 1 1 2 2 2 0 Beta-casein like protein Kinesin PF00225.18 KII88479.1 - 1.4e-108 362.5 0.0 2.8e-108 361.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 KII88479.1 - 5.1e-06 26.6 0.3 5.1e-06 26.6 0.2 4.1 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Utp12 PF04003.7 KII88479.1 - 0.13 12.1 2.1 3.6 7.5 0.0 3.2 2 1 0 2 2 2 0 Dip2/Utp12 Family Elf1 PF05129.8 KII88480.1 - 1.2e-29 101.8 0.9 1.5e-29 101.5 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KII88480.1 - 0.002 18.2 0.5 0.0029 17.7 0.3 1.3 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C554 PF13435.1 KII88480.1 - 0.072 13.1 2.0 0.15 12.1 1.4 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 KII88480.1 - 0.12 12.6 0.9 0.18 12.1 0.4 1.5 1 1 0 1 1 1 0 Cytochrome c3 Kinesin PF00225.18 KII88481.1 - 5.9e-113 376.9 0.5 5.9e-113 376.9 0.3 2.3 3 0 0 3 3 3 1 Kinesin motor domain DUF3584 PF12128.3 KII88481.1 - 0.0015 15.9 19.1 0.0015 15.9 13.3 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_10 PF12846.2 KII88481.1 - 2.3 7.5 14.9 2.2 7.6 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain PUF PF00806.14 KII88483.1 - 4e-65 211.7 7.3 6.3e-10 37.9 0.0 9.1 9 1 1 10 10 10 8 Pumilio-family RNA binding repeat oligo_HPY PF08352.7 KII88483.1 - 0.15 12.4 0.3 3.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Oligopeptide/dipeptide transporter, C-terminal region Sec16_C PF12931.2 KII88484.1 - 5.3e-65 219.9 0.0 7.2e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KII88484.1 - 6.5e-29 100.2 0.0 1.7e-28 98.9 0.0 1.8 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_C PF12931.2 KII88485.1 - 4e-06 26.7 0.1 5.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 OST3_OST6 PF04756.8 KII88486.1 - 1.9e-14 53.5 3.0 2.9e-14 52.9 2.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KII88486.1 - 0.0052 16.4 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin ORMDL PF04061.9 KII88486.1 - 0.094 12.2 4.0 0.22 11.0 2.8 1.6 1 1 0 1 1 1 0 ORMDL family VKOR PF07884.9 KII88486.1 - 0.25 11.1 6.5 3.8 7.3 0.9 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family 7TMR-DISM_7TM PF07695.6 KII88486.1 - 0.36 10.4 10.2 1 8.9 7.1 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4231 PF14015.1 KII88486.1 - 0.87 9.5 4.6 5.6 7.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PI3_PI4_kinase PF00454.22 KII88487.1 - 4.7e-32 111.3 0.0 8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3552 PF12072.3 KII88490.1 - 0.1 11.8 9.0 0.11 11.7 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1090 PF06476.7 KII88490.1 - 0.41 10.3 3.0 7.8 6.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) zf-C4H2 PF10146.4 KII88492.1 - 0.0016 18.5 8.1 0.002 18.1 5.4 1.3 1 1 0 1 1 1 1 Zinc finger-containing protein DUF3829 PF12889.2 KII88492.1 - 0.0027 16.9 1.7 0.0046 16.1 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) CENP-Q PF13094.1 KII88492.1 - 0.005 16.8 10.7 0.0067 16.4 4.8 2.4 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit PV-1 PF06637.6 KII88492.1 - 0.01 14.4 3.5 0.016 13.8 2.4 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CALCOCO1 PF07888.6 KII88492.1 - 0.011 14.0 3.3 0.01 14.1 2.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.14 KII88492.1 - 0.014 14.9 15.3 0.018 14.6 10.2 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF972 PF06156.8 KII88492.1 - 0.028 14.7 4.7 0.028 14.7 3.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Ead_Ea22 PF13935.1 KII88492.1 - 0.047 14.0 8.1 0.026 14.8 3.2 1.9 2 0 0 2 2 2 0 Ead/Ea22-like protein DUF3322 PF11795.3 KII88492.1 - 0.054 13.1 1.9 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) FUSC PF04632.7 KII88492.1 - 0.071 11.5 5.6 0.083 11.3 3.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_23 PF13476.1 KII88492.1 - 0.075 13.3 1.6 0.095 13.0 1.1 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 KII88492.1 - 0.077 13.1 5.6 4.6 7.3 0.1 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF86 PF01934.12 KII88492.1 - 0.08 12.5 0.9 0.17 11.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF86 IFT57 PF10498.4 KII88492.1 - 0.093 11.4 7.5 0.031 13.0 3.5 1.4 2 0 0 2 2 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 KII88492.1 - 0.098 12.2 11.2 0.059 12.9 6.2 1.8 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 KII88492.1 - 0.13 10.7 5.3 0.19 10.1 3.6 1.3 1 1 0 1 1 1 0 AAA domain PEP-utilisers_N PF05524.8 KII88492.1 - 0.13 12.0 6.8 6.7 6.5 3.2 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Rho_Binding PF08912.6 KII88492.1 - 0.13 12.5 8.7 0.2 11.9 3.7 2.7 2 1 0 2 2 2 0 Rho Binding Baculo_PEP_C PF04513.7 KII88492.1 - 0.14 12.0 7.3 3.4 7.5 2.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2580 PF10824.3 KII88492.1 - 0.14 12.4 4.6 0.2 11.9 2.3 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF2580) Syntaxin_2 PF14523.1 KII88492.1 - 0.15 12.1 5.5 0.17 11.9 2.1 2.2 2 1 0 2 2 2 0 Syntaxin-like protein GP41 PF00517.12 KII88492.1 - 0.16 11.4 1.0 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Retroviral envelope protein PrkA PF06798.7 KII88492.1 - 0.2 10.9 5.3 0.12 11.6 1.9 1.8 2 1 0 2 2 2 0 PrkA serine protein kinase C-terminal domain V_ATPase_I PF01496.14 KII88492.1 - 0.2 9.4 2.3 0.19 9.5 1.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 KII88492.1 - 0.21 11.4 12.7 0.056 13.3 6.4 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KII88492.1 - 0.23 11.2 9.5 0.35 10.6 6.6 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RasGAP_C PF03836.10 KII88492.1 - 0.25 11.0 6.0 0.38 10.4 2.5 2.0 2 0 0 2 2 2 0 RasGAP C-terminus Prefoldin PF02996.12 KII88492.1 - 0.29 10.8 8.5 0.4 10.3 1.8 3.0 3 1 0 3 3 3 0 Prefoldin subunit Hemerythrin PF01814.18 KII88492.1 - 0.36 10.9 9.5 0.6 10.2 3.7 2.7 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Sulfatase_C PF14707.1 KII88492.1 - 0.42 10.8 4.3 8.3 6.7 1.2 2.3 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase TMF_TATA_bd PF12325.3 KII88492.1 - 0.49 10.1 13.0 0.15 11.8 5.7 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nsp1_C PF05064.8 KII88492.1 - 0.49 10.0 5.8 0.28 10.8 2.4 1.8 2 0 0 2 2 1 0 Nsp1-like C-terminal region EzrA PF06160.7 KII88492.1 - 0.57 8.3 10.8 0.56 8.3 5.9 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA MAP7 PF05672.6 KII88492.1 - 0.58 9.5 13.5 0.9 8.8 9.4 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family OmpH PF03938.9 KII88492.1 - 0.58 10.0 9.7 0.77 9.6 6.2 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.7 KII88492.1 - 0.67 10.1 7.7 0.4 10.8 3.7 1.8 2 0 0 2 2 1 0 Centromere protein H (CENP-H) DUF16 PF01519.11 KII88492.1 - 0.72 10.1 5.6 0.44 10.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_27 PF13514.1 KII88492.1 - 0.82 7.2 15.5 1.3 6.6 10.3 1.8 1 1 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 KII88492.1 - 0.85 10.0 5.9 1.1 9.7 1.6 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 KII88492.1 - 0.86 8.2 9.9 0.64 8.6 2.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.8 KII88492.1 - 0.89 8.5 4.0 0.69 8.9 1.9 1.5 1 1 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 KII88492.1 - 0.95 8.4 13.7 0.26 10.3 7.5 1.4 2 0 0 2 2 1 0 Autophagy protein Apg6 TMCO5 PF14992.1 KII88492.1 - 0.96 8.5 7.8 0.4 9.7 3.7 1.6 2 0 0 2 2 2 0 TMCO5 family 4HB_MCP_1 PF12729.2 KII88492.1 - 1.2 8.4 8.5 1.2 8.4 4.8 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF607 PF04678.8 KII88492.1 - 1.2 9.0 6.8 0.4 10.5 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF2937 PF11157.3 KII88492.1 - 1.2 8.4 3.7 0.61 9.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FemAB PF02388.11 KII88492.1 - 1.3 7.6 5.2 1.9 7.0 3.6 1.2 1 0 0 1 1 1 0 FemAB family GAS PF13851.1 KII88492.1 - 1.3 8.1 12.6 1.9 7.6 6.9 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding FliD_C PF07195.7 KII88492.1 - 1.6 7.9 5.3 0.71 9.1 1.8 1.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DivIC PF04977.10 KII88492.1 - 1.6 8.2 9.1 3.8 7.0 2.8 2.7 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.6 KII88492.1 - 1.7 8.4 17.0 2.9 7.6 4.8 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) WXG100 PF06013.7 KII88492.1 - 1.8 8.6 7.2 28 4.8 2.5 3.4 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DUF342 PF03961.8 KII88492.1 - 1.8 6.8 8.5 0.72 8.2 4.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TBPIP PF07106.8 KII88492.1 - 1.9 7.9 8.4 1.1 8.8 3.9 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GrpE PF01025.14 KII88492.1 - 2 7.9 13.0 8.7 5.8 6.7 2.6 2 1 0 2 2 2 0 GrpE Herpes_UL6 PF01763.11 KII88492.1 - 2 6.4 6.1 0.97 7.5 2.8 1.5 2 0 0 2 2 2 0 Herpesvirus UL6 like HSCB_C PF07743.8 KII88492.1 - 2.2 8.7 11.7 4.3 7.8 0.0 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain H-kinase_dim PF02895.9 KII88492.1 - 2.2 8.6 6.4 10 6.5 2.5 2.5 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Seryl_tRNA_N PF02403.17 KII88492.1 - 2.4 8.2 12.4 2 8.4 6.4 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.1 KII88492.1 - 2.7 7.8 6.8 4.9 6.9 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NEMO PF11577.3 KII88492.1 - 2.8 7.7 13.5 0.29 10.8 5.1 2.6 3 1 0 3 3 1 0 NF-kappa-B essential modulator NEMO Mnd1 PF03962.10 KII88492.1 - 3 7.4 13.4 9.7 5.8 7.7 2.5 2 1 1 3 3 3 0 Mnd1 family Cep57_MT_bd PF06657.8 KII88492.1 - 3 7.8 9.5 13 5.8 2.0 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 KII88492.1 - 3.1 8.0 8.0 2.6 8.2 3.8 2.1 2 0 0 2 2 2 0 Syntaxin DivIVA PF05103.8 KII88492.1 - 3.6 7.6 13.8 1.2 9.1 6.0 2.6 2 1 0 2 2 2 0 DivIVA protein TMF_DNA_bd PF12329.3 KII88492.1 - 3.8 7.3 14.4 4 7.3 6.3 3.0 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.16 KII88492.1 - 4.9 7.4 11.5 4.8 7.5 4.5 2.7 2 1 1 3 3 3 0 Spectrin repeat Spc24 PF08286.6 KII88492.1 - 4.9 6.8 10.1 1.2 8.8 4.2 2.0 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 Muted PF14942.1 KII88492.1 - 5.5 6.8 11.1 5.2 6.9 5.0 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Enkurin PF13864.1 KII88492.1 - 5.8 7.1 11.6 41 4.4 5.4 2.6 2 1 0 2 2 2 0 Calmodulin-binding FlaF PF07309.6 KII88492.1 - 7.4 6.4 8.5 5.6 6.8 3.8 2.2 2 0 0 2 2 2 0 Flagellar protein FlaF DUF4200 PF13863.1 KII88492.1 - 7.6 6.5 16.1 5.2 7.0 7.4 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) Phage_GP20 PF06810.6 KII88492.1 - 8.1 5.8 11.1 59 3.0 5.8 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF724 PF05266.9 KII88492.1 - 8.6 5.9 11.0 3.4 7.2 5.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Glyco_transf_15 PF01793.11 KII88493.1 - 2.4e-141 470.4 4.4 2.9e-141 470.2 3.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DDE_2 PF02914.10 KII88493.1 - 0.094 12.2 0.0 9.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage Mu transposase Glyco_transf_15 PF01793.11 KII88494.1 - 5.2e-138 459.5 4.8 6.3e-138 459.2 3.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.17 KII88495.1 - 6.8e-76 255.1 4.0 7.8e-76 254.9 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin PolyA_pol PF01743.15 KII88495.1 - 0.0052 17.0 0.0 0.2 11.8 0.0 2.8 2 1 0 2 2 2 1 Poly A polymerase head domain ABC_tran PF00005.22 KII88496.1 - 1.6e-23 83.5 0.0 2.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KII88496.1 - 5.1e-06 26.6 0.0 0.042 13.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KII88496.1 - 5.8e-05 22.4 0.0 0.0075 15.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KII88496.1 - 7.4e-05 22.3 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KII88496.1 - 0.00011 21.8 0.0 0.00065 19.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 KII88496.1 - 0.00017 20.7 0.1 0.00029 20.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KII88496.1 - 0.00029 20.6 0.0 0.0049 16.7 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KII88496.1 - 0.00051 19.7 0.6 0.0012 18.5 0.2 1.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 KII88496.1 - 0.00088 18.7 0.1 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KII88496.1 - 0.001 19.4 0.0 0.0015 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KII88496.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII88496.1 - 0.0011 18.9 0.1 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 KII88496.1 - 0.0023 17.0 0.0 0.026 13.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KII88496.1 - 0.0038 17.5 0.1 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KII88496.1 - 0.0095 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII88496.1 - 0.017 14.5 0.0 0.059 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KII88496.1 - 0.024 15.4 0.6 0.053 14.3 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII88496.1 - 0.036 13.9 0.2 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KII88496.1 - 0.042 13.5 0.3 0.11 12.1 0.1 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 KII88496.1 - 0.044 12.6 0.1 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_ATPase PF09818.4 KII88496.1 - 0.055 12.0 0.4 1.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_13 PF13166.1 KII88496.1 - 0.066 11.6 0.0 0.92 7.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KII88496.1 - 0.069 12.0 0.1 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_2 PF03668.10 KII88496.1 - 0.076 12.0 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_10 PF12846.2 KII88496.1 - 0.079 12.3 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.14 KII88496.1 - 0.086 12.2 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CPT PF07931.7 KII88496.1 - 0.089 12.4 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.4 KII88496.1 - 0.09 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 KII88496.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.18 KII88496.1 - 0.16 11.3 0.3 0.32 10.3 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain tRNA-synt_2d PF01409.15 KII88498.1 - 2.3e-49 167.8 3.3 6.5e-27 94.2 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KII88498.1 - 2.8e-20 72.2 0.1 7.2e-20 70.9 0.1 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.14 KII88499.1 - 1.4e-41 141.7 0.0 2.4e-41 141.0 0.0 1.3 1 1 0 1 1 1 1 GrpE FTHFS PF01268.14 KII88500.1 - 3.4e-256 850.6 0.0 5e-256 850.0 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KII88500.1 - 1.3e-67 225.9 0.2 3.3e-67 224.5 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KII88500.1 - 1e-35 122.3 0.6 2.4e-35 121.0 0.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 KII88500.1 - 0.096 12.5 1.1 3.5 7.4 0.2 3.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PNGaseA PF12222.3 KII88501.1 - 7.5e-84 282.0 5.1 1e-83 281.6 3.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A RRM PF10378.4 KII88501.1 - 0.014 15.0 0.1 0.049 13.2 0.1 2.0 1 0 0 1 1 1 0 Putative RRM domain Pmp3 PF01679.12 KII88502.1 - 1.9e-16 59.4 3.2 2.7e-16 59.0 2.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.6 KII88502.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE SLX9 PF15341.1 KII88502.1 - 0.5 10.8 9.7 0.31 11.4 3.7 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 zf-H2C2_2 PF13465.1 KII88503.1 - 9.3e-22 76.1 23.4 7.2e-08 32.3 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KII88503.1 - 2.5e-19 68.3 30.0 1.2e-05 25.3 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII88503.1 - 1.1e-11 44.2 25.1 0.0018 18.4 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KII88503.1 - 0.25 11.3 7.9 0.32 10.9 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII88503.1 - 0.4 10.8 14.7 0.26 11.4 0.2 4.6 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 KII88503.1 - 0.46 10.1 4.0 7.9 6.2 0.0 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-TRAF PF02176.13 KII88503.1 - 0.5 10.7 9.8 0.58 10.5 1.5 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 KII88503.1 - 0.5 10.6 9.9 1.5 9.1 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF4407 PF14362.1 KII88503.1 - 7.6 5.3 8.7 0.63 8.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FBPase PF00316.15 KII88504.1 - 3.9e-129 430.1 0.0 4.4e-129 429.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KII88504.1 - 0.00015 21.2 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family Amidase PF01425.16 KII88505.1 - 1e-100 337.6 0.2 1.3e-100 337.3 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF2418 PF10332.4 KII88506.1 - 7.9e-26 90.2 0.1 1.6e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Kelch_3 PF13415.1 KII88507.1 - 4.7e-13 48.9 9.3 0.51 10.5 0.0 8.0 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KII88507.1 - 2.2e-12 46.5 15.6 0.3 11.3 0.3 7.3 4 1 2 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KII88507.1 - 4.7e-10 39.2 6.5 0.002 18.0 0.0 6.5 7 1 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 KII88507.1 - 1.2e-07 31.3 17.7 0.09 12.5 0.0 6.7 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KII88507.1 - 6.6e-07 28.7 10.5 0.56 9.7 0.0 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KII88507.1 - 8.2e-07 28.5 5.0 0.54 10.1 0.1 5.5 5 0 0 5 5 5 2 Kelch motif zf-MYND PF01753.13 KII88507.1 - 0.00072 19.3 7.8 0.00072 19.3 5.4 2.4 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.1 KII88507.1 - 0.01 15.7 0.5 0.091 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII88507.1 - 0.068 13.1 6.1 0.46 10.5 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KII88507.1 - 0.075 12.6 2.0 0.4 10.3 1.4 2.1 1 1 0 1 1 1 0 TPR repeat DUF3482 PF11981.3 KII88507.1 - 0.21 10.8 1.4 0.4 9.8 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) TPR_10 PF13374.1 KII88507.1 - 0.34 10.9 1.8 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII88507.1 - 1.1 9.0 3.3 2.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_3 PF13415.1 KII88508.1 - 9.3e-18 63.8 6.6 0.0067 16.5 0.0 7.3 6 2 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KII88508.1 - 3.3e-16 58.7 16.4 0.00055 19.6 0.0 7.2 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KII88508.1 - 6.8e-16 57.8 1.4 0.00033 20.5 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KII88508.1 - 1.2e-14 53.7 11.5 2.6e-05 24.1 0.0 6.9 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.20 KII88508.1 - 2.7e-12 46.0 13.6 5.9e-05 22.5 0.0 7.3 7 1 1 8 8 8 2 Kelch motif TPR_12 PF13424.1 KII88508.1 - 2.9e-05 23.9 0.9 0.48 10.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Kelch_2 PF07646.10 KII88508.1 - 0.00057 19.5 12.6 0.083 12.6 0.1 6.2 6 1 0 6 6 6 1 Kelch motif zf-MYND PF01753.13 KII88508.1 - 0.00069 19.4 8.6 0.0017 18.1 6.0 1.7 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 KII88508.1 - 0.0022 17.6 1.7 0.012 15.1 1.2 2.2 1 1 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KII88508.1 - 0.0027 17.4 6.0 0.19 11.7 2.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII88508.1 - 0.027 15.0 1.6 0.63 10.8 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII88508.1 - 0.061 12.9 2.9 4.5 7.0 1.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KII88508.1 - 0.075 12.8 1.7 0.32 10.8 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KII88508.1 - 0.1 13.3 2.3 0.38 11.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KII88508.1 - 0.13 12.2 1.5 45 4.1 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-MYND PF01753.13 KII88509.1 - 8.1e-10 38.4 13.1 8.1e-10 38.4 9.1 4.3 3 1 0 3 3 3 2 MYND finger FYVE_2 PF02318.11 KII88509.1 - 7.1e-05 22.6 6.3 7.1e-05 22.6 4.4 2.8 2 1 1 3 3 3 1 FYVE-type zinc finger UPF0086 PF01868.11 KII88510.1 - 2.2e-21 75.3 0.0 1.7e-20 72.4 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function UPF0086 WxL PF13731.1 KII88510.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 WxL domain surface cell wall-binding SpoIIE PF07228.7 KII88511.1 - 6.3e-14 52.1 0.0 9.3e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KII88511.1 - 0.00021 20.7 0.0 0.00051 19.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KII88511.1 - 0.011 15.1 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C Peptidase_M49 PF03571.10 KII88512.1 - 5.1e-189 628.8 0.0 6.3e-189 628.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Cellulase PF00150.13 KII88513.1 - 1.2e-13 50.9 6.1 5.6e-13 48.7 4.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KII88513.1 - 0.00019 21.7 0.1 0.00055 20.3 0.0 1.8 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KII88513.1 - 0.029 13.5 1.0 0.18 10.9 0.4 2.4 2 1 0 2 2 2 0 Beta-galactosidase TPR_12 PF13424.1 KII88514.1 - 1.1e-05 25.2 4.4 1.2 9.1 0.0 4.1 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII88514.1 - 0.0024 17.6 0.8 8.3 6.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII88514.1 - 0.0035 16.8 0.2 0.57 9.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII88514.1 - 0.007 16.0 0.0 13 5.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII88514.1 - 0.042 13.5 0.2 11 5.7 0.0 3.0 3 0 0 3 3 3 0 TPR repeat DUF1227 PF06777.6 KII88515.1 - 1.5e-56 190.1 0.0 2.8e-56 189.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KII88515.1 - 5.4e-48 162.6 0.3 1.9e-47 160.9 0.0 2.1 3 0 0 3 3 3 1 DEAD_2 Helicase_C_2 PF13307.1 KII88515.1 - 1.3e-41 142.3 0.0 2.5e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 KII88515.1 - 0.0013 18.3 0.0 0.33 10.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KII88515.1 - 0.0048 16.7 0.0 0.025 14.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KII88515.1 - 0.0083 14.9 0.0 0.48 9.1 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KII88515.1 - 0.089 12.9 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Peptidase_M41 PF01434.13 KII88517.1 - 5e-66 222.2 4.0 1.3e-65 220.8 2.8 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KII88517.1 - 1.3e-43 148.4 0.2 3.8e-43 146.8 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KII88517.1 - 6.7e-05 23.6 0.0 0.0003 21.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KII88517.1 - 8.4e-05 21.4 0.0 0.00022 20.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KII88517.1 - 0.00025 20.7 0.7 0.0017 18.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KII88517.1 - 0.00047 20.3 0.6 0.049 13.7 0.4 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII88517.1 - 0.00094 18.2 0.0 0.0024 16.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KII88517.1 - 0.0014 18.9 0.3 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII88517.1 - 0.0015 18.5 4.3 0.027 14.4 0.1 3.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 KII88517.1 - 0.0018 17.9 0.7 0.0056 16.3 0.5 1.8 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KII88517.1 - 0.0023 17.0 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KaiC PF06745.8 KII88517.1 - 0.0029 16.7 0.5 0.17 10.9 0.1 2.5 1 1 0 2 2 2 1 KaiC AAA_14 PF13173.1 KII88517.1 - 0.0031 17.3 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KII88517.1 - 0.0053 16.1 0.1 0.016 14.6 0.1 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 KII88517.1 - 0.0065 15.4 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 KII88517.1 - 0.008 16.1 0.9 0.013 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KII88517.1 - 0.009 15.9 0.3 0.037 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KII88517.1 - 0.012 14.7 0.4 0.028 13.5 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KII88517.1 - 0.015 14.7 1.4 0.13 11.6 0.5 2.5 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KII88517.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII88517.1 - 0.079 12.6 0.4 0.36 10.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KII88517.1 - 0.095 12.1 0.3 0.83 9.1 0.2 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain GCIP PF13324.1 KII88518.1 - 3.1e-10 39.7 0.0 5.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting F-box-like PF12937.2 KII88519.1 - 2.8e-06 26.9 0.1 6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88519.1 - 9.2e-05 21.9 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain Glycos_transf_2 PF00535.21 KII88520.1 - 8e-33 113.4 0.0 1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KII88520.1 - 3.4e-13 49.9 0.0 4.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KII88520.1 - 9.8e-10 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KII88520.1 - 0.017 15.3 0.0 0.058 13.7 0.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase family 2 zf-MYND PF01753.13 KII88521.1 - 5.8e-07 29.2 10.9 5.8e-07 29.2 7.6 4.8 3 1 1 4 4 4 3 MYND finger Oxidored_FMN PF00724.15 KII88522.1 - 7e-69 232.4 0.0 8.7e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family LRR_4 PF12799.2 KII88523.1 - 0.0081 15.7 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Glucan_synthase PF02364.10 KII88524.1 - 0 1362.5 0.2 0 1361.9 0.1 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KII88524.1 - 5.6e-39 132.6 0.1 1.5e-38 131.3 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 F-box-like PF12937.2 KII88525.1 - 5.3e-08 32.4 0.1 9.1e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 F-box-like Osmo_CC PF08946.5 KII88525.1 - 0.017 15.0 1.7 0.035 14.1 1.1 1.6 1 1 0 1 1 1 0 Osmosensory transporter coiled coil DUF4254 PF14063.1 KII88525.1 - 0.045 13.3 0.5 0.055 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DUF4200 PF13863.1 KII88525.1 - 0.13 12.2 0.5 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) F-box PF00646.28 KII88525.1 - 0.56 9.9 2.8 0.63 9.7 0.8 2.1 2 1 0 2 2 2 0 F-box domain DUF3958 PF13125.1 KII88527.1 - 0.054 13.3 0.3 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) IncA PF04156.9 KII88527.1 - 1.4 8.4 15.4 0.17 11.4 1.5 2.9 2 1 0 2 2 2 0 IncA protein DMPK_coil PF08826.5 KII88527.1 - 4.9 7.1 17.9 0.057 13.3 0.9 4.3 5 0 0 5 5 5 0 DMPK coiled coil domain like SlyX PF04102.7 KII88528.1 - 0.0074 16.6 6.1 0.2 12.0 1.6 3.6 4 0 0 4 4 4 1 SlyX Atg14 PF10186.4 KII88528.1 - 0.015 14.3 6.8 0.015 14.2 2.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 KII88528.1 - 0.034 14.4 4.7 0.98 9.7 1.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) ADIP PF11559.3 KII88528.1 - 0.036 13.9 10.6 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 KII88528.1 - 0.15 12.2 3.1 0.16 12.0 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_CLD_2 PF14197.1 KII88528.1 - 0.34 10.8 9.8 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Mnd1 PF03962.10 KII88528.1 - 0.76 9.4 6.3 2.3 7.8 1.3 2.3 2 0 0 2 2 2 0 Mnd1 family Prefoldin_2 PF01920.15 KII88528.1 - 2 8.2 13.3 0.82 9.4 3.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 KII88528.1 - 2.4 8.6 8.6 2.9 8.3 0.2 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Hrs_helical PF12210.3 KII88528.1 - 2.6 8.3 7.1 15 5.8 3.4 2.8 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IncA PF04156.9 KII88528.1 - 9.1 5.8 10.1 16 4.9 2.9 2.3 2 0 0 2 2 2 0 IncA protein RAI16-like PF10257.4 KII88529.1 - 4.5e-73 246.2 0.1 7.4e-73 245.5 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein F-box-like PF12937.2 KII88530.1 - 5.3e-06 26.0 0.3 8.3e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 F-box-like CLASP_N PF12348.3 KII88531.1 - 2e-22 79.6 0.0 2.5e-10 40.0 0.0 4.6 4 0 0 4 4 4 3 CLASP N terminal HEAT_2 PF13646.1 KII88531.1 - 2.5e-13 50.1 19.0 0.0016 18.7 0.0 9.2 9 3 1 10 10 10 4 HEAT repeats HEAT PF02985.17 KII88531.1 - 8.2e-12 44.1 10.8 0.38 10.9 0.0 11.1 13 0 0 13 13 13 4 HEAT repeat HEAT_EZ PF13513.1 KII88531.1 - 9.3e-07 29.1 12.9 0.23 11.9 0.0 8.8 8 1 1 9 9 9 2 HEAT-like repeat TAN PF11640.3 KII88531.1 - 0.00017 21.3 0.4 0.25 11.0 0.0 4.9 5 0 0 5 5 5 1 Telomere-length maintenance and DNA damage repair Proteasom_PSMB PF10508.4 KII88531.1 - 0.041 12.1 0.0 1 7.5 0.0 2.5 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit SMC_Nse1 PF07574.8 KII88531.1 - 0.4 10.2 0.0 19 4.7 0.0 2.7 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Prot_inhib_II PF02428.10 KII88532.1 - 1.1 9.3 5.8 0.14 12.1 1.0 1.8 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family IF-2B PF01008.12 KII88534.1 - 4.2e-57 193.2 0.0 5.9e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M24 PF00557.19 KII88536.1 - 5.7e-46 156.7 0.0 7.7e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KII88536.1 - 0.0002 21.1 3.7 0.00042 20.1 2.6 1.5 1 0 0 1 1 1 1 MYND finger Acyltransferase PF01553.16 KII88537.1 - 1.7e-13 50.1 0.0 6.4e-12 45.0 0.0 2.9 2 1 0 2 2 2 1 Acyltransferase Cyclin_N PF00134.18 KII88538.1 - 1.4e-15 56.9 0.1 3.1e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KII88538.1 - 2.5e-06 27.4 0.2 0.098 12.5 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 KII88538.1 - 6.5e-05 22.6 0.1 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat EndIII_4Fe-2S PF10576.4 KII88542.1 - 1 9.6 0.1 1 9.6 0.1 2.9 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III zf-A20 PF01754.11 KII88542.1 - 9.5 5.9 7.0 16 5.2 0.2 2.8 3 0 0 3 3 3 0 A20-like zinc finger Ribosomal_S21 PF01165.15 KII88543.1 - 6.6e-11 41.4 9.0 6.6e-11 41.4 6.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S21 RWD PF05773.17 KII88544.1 - 6.5e-18 64.6 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain Abhydrolase_6 PF12697.2 KII88545.1 - 1.1e-12 48.3 0.2 1.7e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII88545.1 - 0.0011 18.7 0.1 0.0033 17.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII88545.1 - 0.0038 16.8 0.0 0.007 15.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 KII88545.1 - 0.044 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Rubis-subs-bind PF09273.6 KII88547.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KII88547.1 - 0.0067 16.7 2.1 0.028 14.7 1.2 2.0 1 1 0 1 1 1 1 SET domain adh_short PF00106.20 KII88548.1 - 1.1e-30 106.7 3.5 1.4e-30 106.4 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII88548.1 - 1.2e-12 47.8 0.9 1.5e-12 47.5 0.7 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII88548.1 - 1.3e-11 44.7 0.2 1.7e-11 44.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KII88548.1 - 2.3e-05 24.0 1.6 5e-05 23.0 1.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KII88548.1 - 0.012 15.0 0.2 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Helicase_RecD PF05127.9 KII88548.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Helicase DUF1776 PF08643.5 KII88548.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4157 PF13699.1 KII88550.1 - 0.017 15.2 0.2 0.035 14.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) DUF2583 PF10762.4 KII88551.1 - 0.018 15.1 4.2 3.4 7.8 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Ninjurin PF04923.7 KII88551.1 - 2.5 7.8 6.4 0.28 10.9 0.2 2.4 3 0 0 3 3 3 0 Ninjurin Paired_CXXCH_1 PF09699.5 KII88554.1 - 0.082 12.4 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) HALZ PF02183.13 KII88555.1 - 0.24 11.1 1.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1192 PF06698.6 KII88555.1 - 0.38 10.5 5.6 0.27 11.0 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Striatin PF08232.7 KII88555.1 - 0.43 10.8 0.0 0.43 10.8 0.0 3.5 2 1 1 3 3 3 0 Striatin family DUF4140 PF13600.1 KII88555.1 - 7.7 7.0 11.1 0.22 11.9 2.5 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Transpos_assoc PF13963.1 KII88556.1 - 0.04 13.8 0.2 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 Transposase-associated domain DnaJ PF00226.26 KII88557.1 - 1.7e-19 69.2 3.4 5e-19 67.8 2.3 1.9 1 0 0 1 1 1 1 DnaJ domain PilJ PF13675.1 KII88558.1 - 0.02 15.1 2.3 0.9 9.8 0.2 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sec8_exocyst PF04048.9 KII88558.1 - 0.06 12.9 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MSC PF09402.5 KII88559.1 - 1.6e-55 188.1 0.0 2.4e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KII88559.1 - 1.6e-11 43.5 0.0 4.6e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain UEV PF05743.8 KII88560.1 - 4.7e-34 116.6 0.0 6.9e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KII88560.1 - 7.1e-28 96.0 1.7 8.6e-28 95.7 0.3 1.9 2 0 0 2 2 2 1 Vps23 core domain HemeBinding_Shp PF11545.3 KII88560.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp TEA PF01285.13 KII88561.1 - 4.5e-08 32.6 1.4 8e-08 31.8 1.0 1.6 1 1 0 1 1 1 1 TEA/ATTS domain family NOC3p PF07540.6 KII88562.1 - 3.6e-26 91.2 2.7 4.5e-26 90.9 0.0 2.6 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 KII88562.1 - 1.9e-21 76.2 0.0 8.1e-21 74.1 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family COPI_C PF06957.6 KII88562.1 - 1.3 7.4 5.9 3.8 5.9 0.6 2.4 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Apc5 PF12862.2 KII88563.1 - 1e-06 28.4 0.1 0.00017 21.3 0.1 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 5 Chordopox_A13L PF05961.6 KII88566.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Conotoxin PF02950.12 KII88566.1 - 6.4 7.6 6.3 10 6.9 0.1 3.6 2 1 2 4 4 4 0 Conotoxin Pyr_redox_2 PF07992.9 KII88568.1 - 1.9e-06 27.8 0.0 2.3e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII88568.1 - 0.0014 18.4 0.0 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KII88568.1 - 0.013 14.4 0.4 0.1 11.5 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Kelch_1 PF01344.20 KII88568.1 - 0.026 14.0 0.2 0.38 10.3 0.0 2.7 3 0 0 3 3 3 0 Kelch motif K_oxygenase PF13434.1 KII88568.1 - 0.11 11.3 0.4 0.21 10.4 0.1 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cu_bind_like PF02298.12 KII88570.1 - 1.2e-05 25.0 0.3 2.8e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Adaptin_N PF01602.15 KII88571.1 - 1.4e-135 452.5 1.8 1.8e-135 452.2 1.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KII88571.1 - 1.5e-22 80.2 0.2 4.9e-21 75.3 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KII88571.1 - 9.1e-17 61.1 6.1 2e-09 37.5 0.2 5.1 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KII88571.1 - 3e-08 33.0 3.3 0.051 13.6 0.0 5.6 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 KII88571.1 - 0.00011 21.9 3.4 0.2 11.5 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KII88571.1 - 0.0015 17.9 0.1 0.15 11.4 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.1 KII88571.1 - 0.0018 18.6 5.2 4.3 7.9 0.0 6.0 4 2 2 6 6 6 1 HEAT-like repeat Proteasom_PSMB PF10508.4 KII88571.1 - 0.019 13.2 0.1 0.43 8.7 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit DUF1548 PF07579.6 KII88571.1 - 0.03 14.4 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DUF4477 PF14780.1 KII88572.1 - 8e-06 25.3 0.0 9.3e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) APC_crr PF05923.7 KII88572.1 - 0.19 11.4 2.0 0.49 10.0 1.4 1.7 1 0 0 1 1 1 0 APC cysteine-rich region Ribosomal_60s PF00428.14 KII88573.1 - 0.057 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein OTU PF02338.14 KII88574.1 - 3.8e-18 66.2 0.0 1e-17 64.8 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KII88574.1 - 0.0059 15.9 0.0 2.2 7.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain Aldo_ket_red PF00248.16 KII88575.1 - 2.9e-46 157.5 0.0 3.3e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4172 PF13776.1 KII88576.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) ECH PF00378.15 KII88577.1 - 3.4e-23 82.0 0.0 4.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AA_permease PF00324.16 KII88578.1 - 4.3e-126 421.0 38.5 5.1e-126 420.8 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII88578.1 - 2.9e-33 115.0 41.2 3.6e-33 114.7 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pirin PF02678.11 KII88579.1 - 4e-31 107.0 0.6 7.4e-31 106.1 0.4 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KII88579.1 - 8.4e-27 93.2 0.1 9.4e-26 89.9 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KII88579.1 - 0.29 10.6 2.7 0.64 9.5 1.2 2.1 2 0 0 2 2 2 0 Cupin domain WD40 PF00400.27 KII88580.1 - 0.0054 16.5 0.2 0.044 13.6 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ PF01011.16 KII88580.1 - 0.12 11.9 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat CLTH PF10607.4 KII88581.1 - 1.7e-20 73.1 0.0 3.1e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KII88581.1 - 2.4e-18 65.5 0.8 5.1e-18 64.5 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KII88581.1 - 8.9e-05 21.8 1.6 0.00015 21.0 0.1 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KII88581.1 - 0.0016 18.2 0.3 0.0031 17.3 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KII88581.1 - 0.0047 16.6 0.3 0.0084 15.8 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 KII88581.1 - 0.0084 15.6 1.7 0.062 12.8 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 KII88581.1 - 0.013 15.5 0.6 0.022 14.7 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII88581.1 - 0.021 14.4 0.4 0.033 13.8 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII88581.1 - 0.028 14.0 0.6 0.049 13.2 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sfi1 PF08457.5 KII88582.1 - 2e-27 95.8 105.6 1.7e-11 43.2 23.5 4.6 1 1 3 4 4 4 4 Sfi1 spindle body protein Methyltransf_11 PF08241.7 KII88583.1 - 3e-06 27.6 0.0 5.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII88583.1 - 0.00051 19.7 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII88583.1 - 0.0017 18.8 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII88583.1 - 0.0027 17.2 0.0 0.0058 16.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII88583.1 - 0.0028 18.1 0.0 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Glyco_tran_28_C PF04101.11 KII88584.1 - 7.3e-29 100.5 0.0 8.9e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KII88584.1 - 6.4e-06 25.5 0.0 7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 P5CR_dimer PF14748.1 KII88585.1 - 3.2e-38 130.0 2.5 3.6e-38 129.8 0.9 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KII88585.1 - 2.1e-12 47.3 0.0 2.6e-10 40.5 0.0 2.6 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 KII88586.1 - 2.5e-44 150.6 0.0 7.2e-44 149.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII88586.1 - 6.7e-09 35.5 0.1 2.2e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KII88586.1 - 7.6e-08 32.4 0.2 2.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KII88586.1 - 3.3e-07 30.4 0.1 2.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII88586.1 - 5.9e-07 29.6 0.6 0.00013 22.0 0.4 3.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 KII88586.1 - 5.5e-06 25.4 0.1 1.1e-05 24.5 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 KII88586.1 - 9.5e-05 22.4 0.0 0.00036 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KII88586.1 - 0.00012 22.0 0.0 0.00082 19.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KII88586.1 - 0.00016 21.3 0.2 0.00043 19.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KII88586.1 - 0.00077 18.5 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KII88586.1 - 0.00079 20.2 0.0 0.0043 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII88586.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KII88586.1 - 0.0019 17.9 0.2 0.06 13.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KII88586.1 - 0.0024 17.5 0.1 0.022 14.3 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 KII88586.1 - 0.0028 17.1 0.9 0.0067 15.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KII88586.1 - 0.0037 17.5 0.1 0.07 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KII88586.1 - 0.0038 16.9 1.0 0.011 15.4 0.0 2.3 3 0 0 3 3 2 1 NTPase AAA_11 PF13086.1 KII88586.1 - 0.0038 16.8 0.1 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KII88586.1 - 0.0038 17.1 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KII88586.1 - 0.0044 16.4 3.7 0.015 14.7 0.1 2.5 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 KII88586.1 - 0.0049 15.6 0.0 0.0092 14.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KII88586.1 - 0.0071 15.5 0.1 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KII88586.1 - 0.0093 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KII88586.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KII88586.1 - 0.013 15.0 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII88586.1 - 0.022 14.4 1.2 0.3 10.7 0.0 2.8 2 1 0 3 3 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 KII88586.1 - 0.028 13.2 0.4 0.074 11.8 0.0 1.9 3 0 0 3 3 3 0 AFG1-like ATPase Zeta_toxin PF06414.7 KII88586.1 - 0.033 13.2 0.1 0.08 12.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Bac_DnaA PF00308.13 KII88586.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 KII88586.1 - 0.065 12.7 0.2 1 8.8 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 KII88586.1 - 0.082 12.3 0.2 0.62 9.4 0.1 2.4 1 1 1 2 2 2 0 AAA-like domain KaiC PF06745.8 KII88586.1 - 0.1 11.6 0.9 0.42 9.7 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 KII88586.1 - 0.12 12.7 3.1 0.8 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KII88586.1 - 0.12 12.7 0.2 0.56 10.5 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 KII88586.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KII88586.1 - 0.12 12.3 0.0 0.58 10.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain RRM_1 PF00076.17 KII88587.1 - 7.2e-12 44.7 0.1 3.4e-11 42.6 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII88587.1 - 4e-08 33.1 0.0 6.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII88587.1 - 6.2e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII88588.1 - 0.0022 17.9 0.0 0.025 14.5 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14e PF01929.12 KII88589.1 - 1e-26 93.0 0.9 1.5e-26 92.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KII88589.1 - 8.4e-06 25.3 0.2 8.4e-06 25.3 0.1 2.0 2 0 0 2 2 2 1 KOW motif DUF2561 PF10812.3 KII88590.1 - 0.029 13.9 0.7 0.042 13.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF1777 PF08648.7 KII88591.1 - 3.5e-25 88.7 44.9 3.5e-25 88.7 31.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KII88591.1 - 3.6 5.9 17.1 4.4 5.6 11.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SUI1 PF01253.17 KII88592.1 - 2.7e-30 103.9 1.2 3.3e-30 103.7 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF608 PF04685.8 KII88592.1 - 0.021 13.5 0.0 0.023 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Flu_B_NS1 PF02942.9 KII88592.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Nop53 PF07767.6 KII88593.1 - 0.07 12.1 13.2 0.089 11.7 9.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2890 PF11081.3 KII88593.1 - 0.47 10.4 10.6 0.69 9.9 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Peptidase_S30 PF01577.11 KII88593.1 - 1.8 7.9 6.3 2.7 7.3 4.3 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Nop14 PF04147.7 KII88593.1 - 1.8 6.3 13.3 2.4 5.9 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 KII88594.1 - 1.1e-20 74.3 0.2 1.8e-20 73.6 0.1 1.4 1 1 0 1 1 1 1 PPP4R2 PAP2 PF01569.16 KII88595.1 - 5.5e-27 93.9 2.9 9.8e-27 93.1 2.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily Ribosomal_S21e PF01249.13 KII88596.1 - 1.7e-36 124.0 0.0 1.8e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e adh_short PF00106.20 KII88597.1 - 2.2e-18 66.7 0.1 6.5e-18 65.2 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII88597.1 - 2.7e-09 36.9 0.0 6.8e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KII88597.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KII88597.1 - 0.00028 21.0 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KII88597.1 - 0.0011 19.0 0.3 0.0019 18.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KII88597.1 - 0.0062 15.5 0.2 0.0091 15.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KII88597.1 - 0.015 14.7 0.1 0.038 13.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2807 PF10988.3 KII88597.1 - 0.031 13.8 0.5 0.051 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) AdoHcyase_NAD PF00670.16 KII88597.1 - 0.086 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BMC PF00936.14 KII88597.1 - 0.16 11.6 2.7 1.8 8.3 0.8 2.8 1 1 1 3 3 3 0 BMC domain F-box-like PF12937.2 KII88598.1 - 4.5e-06 26.2 1.8 1.2e-05 24.9 1.3 1.8 1 0 0 1 1 1 1 F-box-like RabGAP-TBC PF00566.13 KII88599.1 - 3.1e-41 141.1 5.3 1.1e-39 136.1 1.1 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 KII88599.1 - 2.8e-08 33.3 0.0 0.00011 21.5 0.0 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) TALPID3 PF15324.1 KII88599.1 - 0.15 9.3 1.0 0.26 8.6 0.7 1.3 1 0 0 1 1 1 0 Hedgehog signalling target DcpS_C PF11969.3 KII88600.1 - 2.9e-13 50.0 1.2 3.4e-13 49.8 0.1 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KII88600.1 - 2.8e-09 37.3 0.0 6.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 HIT domain zf-C2H2_2 PF12756.2 KII88600.1 - 0.062 13.4 2.7 0.06 13.4 0.8 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ox_reductase_C PF08635.5 KII88601.1 - 3.8e-72 240.3 0.2 5.6e-72 239.7 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 KII88601.1 - 4.4e-22 78.8 0.0 1.1e-21 77.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII88601.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain TA0956 PF11513.3 KII88601.1 - 0.038 14.0 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 HALZ PF02183.13 KII88602.1 - 0.0037 16.9 1.7 0.0071 16.0 1.1 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.12 KII88602.1 - 0.034 14.4 3.3 0.05 13.8 2.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF972 PF06156.8 KII88602.1 - 0.047 14.0 2.2 0.061 13.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF489 PF04356.7 KII88602.1 - 0.056 13.0 0.1 0.06 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF904 PF06005.7 KII88602.1 - 0.083 13.1 3.3 0.13 12.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Matrilin_ccoil PF10393.4 KII88602.1 - 0.19 11.1 1.8 0.31 10.4 1.3 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DivIC PF04977.10 KII88602.1 - 0.25 10.8 5.8 0.36 10.3 4.0 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF2681 PF10883.3 KII88602.1 - 1.4 9.2 5.5 1.9 8.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) IncA PF04156.9 KII88602.1 - 2.1 7.8 6.0 2.2 7.8 4.1 1.2 1 1 0 1 1 1 0 IncA protein CBM_48 PF02922.13 KII88603.1 - 0.014 15.4 0.3 0.086 12.8 0.0 2.5 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PIG-Y PF15159.1 KII88604.1 - 5.1e-11 42.6 0.8 5.4e-11 42.5 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SBF PF01758.11 KII88604.1 - 0.066 12.6 0.3 0.069 12.5 0.2 1.0 1 0 0 1 1 1 0 Sodium Bile acid symporter family Aminotran_1_2 PF00155.16 KII88605.1 - 2.2e-83 280.1 0.0 2.5e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-AN1 PF01428.11 KII88606.1 - 3.7e-09 36.3 9.1 3.7e-09 36.3 6.3 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 KII88606.1 - 0.093 12.6 8.7 0.13 12.1 5.9 1.4 1 1 0 1 1 1 0 IBR domain ERO1 PF04137.10 KII88606.1 - 0.39 9.6 3.1 0.42 9.5 2.1 1.0 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_ligase_ZBD PF03119.11 KII88606.1 - 7.1 6.4 10.1 1.9 8.2 0.6 3.4 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain SNARE PF05739.14 KII88608.1 - 7.3e-14 51.2 1.1 7.3e-14 51.2 0.7 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KII88608.1 - 1.3e-13 50.9 4.4 1.3e-12 47.8 0.2 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KII88608.1 - 8.1e-05 22.2 2.9 0.00091 18.8 1.1 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Tweety PF04906.8 KII88608.1 - 0.00046 18.7 1.2 0.0029 16.0 0.1 2.0 2 0 0 2 2 2 1 Tweety Use1 PF09753.4 KII88608.1 - 0.00058 19.3 1.9 0.0008 18.9 1.3 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4094 PF13334.1 KII88608.1 - 0.035 14.4 1.2 0.7 10.3 0.0 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF4094) VitD-bind_III PF09164.5 KII88608.1 - 0.04 13.5 0.4 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Syntaxin_2 PF14523.1 KII88608.1 - 0.041 13.9 8.7 0.03 14.3 3.2 2.2 2 0 0 2 2 2 0 Syntaxin-like protein ABC2_membrane_3 PF12698.2 KII88608.1 - 0.044 12.8 0.1 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF805 PF05656.9 KII88608.1 - 0.046 13.5 0.2 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) AvrPphF-ORF-2 PF09143.5 KII88608.1 - 0.086 12.5 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 AvrPphF-ORF-2 Rifin_STEVOR PF02009.11 KII88608.1 - 0.099 12.2 7.8 0.19 11.3 4.8 1.7 1 1 1 2 2 2 0 Rifin/stevor family Spectrin PF00435.16 KII88608.1 - 0.1 12.8 3.5 4.8 7.5 0.1 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF4407 PF14362.1 KII88608.1 - 0.11 11.4 6.6 0.17 10.8 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMEM154 PF15102.1 KII88608.1 - 0.16 11.6 1.2 0.33 10.6 0.8 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 KII88608.1 - 0.24 11.4 1.8 0.57 10.2 1.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tmemb_55A PF09788.4 KII88608.1 - 0.26 10.3 0.9 0.43 9.6 0.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A BRO1 PF03097.13 KII88608.1 - 0.45 9.2 3.6 2.8 6.5 0.2 2.1 2 0 0 2 2 2 0 BRO1-like domain Neur_chan_memb PF02932.11 KII88608.1 - 0.56 10.0 2.4 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spc7 PF08317.6 KII88608.1 - 0.87 8.1 7.5 0.55 8.8 0.4 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3753 PF12575.3 KII88608.1 - 1.1 9.1 6.3 0.96 9.2 3.2 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3753) Synaptobrevin PF00957.16 KII88608.1 - 1.5 8.4 12.0 0.45 10.1 4.0 2.7 2 1 0 2 2 2 0 Synaptobrevin Hexapep PF00132.19 KII88609.1 - 1.1e-13 50.0 10.6 4.3e-05 22.8 0.4 4.7 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KII88609.1 - 4e-09 36.1 0.0 6.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase W2 PF02020.13 KII88609.1 - 1.3e-06 28.2 0.0 1.3e-06 28.2 0.0 2.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 KII88609.1 - 0.0001 21.7 11.9 0.043 13.3 2.1 3.4 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KII88609.1 - 0.00035 20.6 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.7 KII88609.1 - 0.0053 15.3 0.5 0.0086 14.6 0.4 1.3 1 0 0 1 1 1 1 L-fucokinase Pmp3 PF01679.12 KII88610.1 - 6.8e-27 92.9 6.4 7.5e-27 92.7 4.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DctM PF06808.7 KII88610.1 - 0.034 12.7 0.5 0.033 12.7 0.4 1.0 1 0 0 1 1 1 0 DctM-like transporters Abhydrolase_5 PF12695.2 KII88611.1 - 7.3e-10 38.7 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KII88611.1 - 2.6e-07 30.4 0.3 4.7e-07 29.5 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aminotran_5 PF00266.14 KII88612.1 - 3.3e-15 55.6 0.0 4.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.14 KII88613.1 - 5.6e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KII88613.1 - 5.3e-06 26.7 0.0 0.00015 22.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII88613.1 - 1.4e-05 24.1 0.0 0.0011 17.9 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII88613.1 - 0.00083 19.3 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KII88613.1 - 0.00086 18.2 0.0 0.0013 17.6 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KII88613.1 - 0.0013 18.5 0.1 0.007 16.2 0.0 2.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KII88613.1 - 0.0047 16.6 0.1 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KII88613.1 - 0.011 14.2 0.6 0.018 13.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KII88613.1 - 0.013 15.0 0.2 0.065 12.8 0.1 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 KII88613.1 - 0.018 13.9 0.0 0.071 11.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.2 KII88613.1 - 0.021 13.9 0.1 0.26 10.2 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KII88613.1 - 0.024 13.2 0.0 3.2 6.2 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase XdhC_C PF13478.1 KII88613.1 - 0.075 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_binding_2 PF00890.19 KII88613.1 - 0.09 11.6 0.2 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KII88613.1 - 0.11 12.3 1.2 0.2 11.4 0.2 1.9 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 KII88613.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AT_hook PF02178.14 KII88614.1 - 0.00015 21.0 55.2 0.11 12.2 4.8 4.6 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.8 KII88615.1 - 3.5e-14 53.3 0.0 7.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KII88615.1 - 2e-06 27.3 0.0 1.2e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase PF00069.20 KII88616.1 - 2.1e-48 164.7 0.0 2.7e-47 161.1 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88616.1 - 7.9e-20 71.0 0.0 1.8e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII88616.1 - 0.0032 17.2 0.1 0.0095 15.6 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ndc1_Nup PF09531.5 KII88616.1 - 0.004 15.6 1.2 0.004 15.6 0.8 3.2 3 0 0 3 3 3 1 Nucleoporin protein Ndc1-Nup TMEM171 PF15471.1 KII88616.1 - 3.5 6.3 6.7 11 4.7 4.6 1.8 1 0 0 1 1 1 0 Transmembrane protein family 171 Elongin_A PF06881.6 KII88618.1 - 0.073 13.4 0.7 0.098 13.0 0.2 1.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_N_3 PF13417.1 KII88619.1 - 4.3e-14 52.4 0.0 9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII88619.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII88619.1 - 0.00059 19.7 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII88619.1 - 0.0013 18.6 0.6 0.0071 16.2 0.4 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII88619.1 - 0.018 15.2 0.0 0.067 13.3 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII88619.1 - 0.021 15.2 0.1 0.044 14.2 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII88621.1 - 7.5e-14 51.7 0.0 2e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII88621.1 - 8.3e-10 38.5 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII88621.1 - 7e-06 25.8 0.1 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII88621.1 - 1.6e-05 24.7 0.0 3.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII88621.1 - 0.00044 20.6 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII88621.1 - 0.0078 16.3 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PIG-H PF10181.4 KII88622.1 - 2.5e-12 46.2 0.0 3.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ist1 PF03398.9 KII88623.1 - 3.7e-34 117.5 0.0 5.7e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 KII88623.1 - 9.2e-11 41.6 0.1 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1697 PF08002.6 KII88623.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Ion_trans PF00520.26 KII88625.1 - 0.00042 19.6 0.2 0.00062 19.0 0.1 1.2 1 0 0 1 1 1 1 Ion transport protein Uds1 PF15456.1 KII88625.1 - 0.065 13.2 0.1 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF972 PF06156.8 KII88625.1 - 0.091 13.1 1.0 0.13 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3186 PF11382.3 KII88625.1 - 0.12 11.5 0.4 0.16 11.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) KfrA_N PF11740.3 KII88625.1 - 0.19 12.1 4.7 0.66 10.4 1.7 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIC PF04977.10 KII88625.1 - 0.34 10.4 2.8 0.6 9.6 1.9 1.4 1 0 0 1 1 1 0 Septum formation initiator NAC PF01849.13 KII88627.1 - 3.3e-20 71.3 0.0 5.5e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 KII88627.1 - 0.0012 18.6 0.1 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 KII88627.1 - 0.027 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF1264 PF06884.6 KII88628.1 - 6.9e-66 220.9 0.2 8.7e-66 220.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Hamartin PF04388.7 KII88629.1 - 3.4e-13 49.1 16.2 3.4e-13 49.1 11.2 2.4 1 1 1 2 2 2 1 Hamartin protein HSP90 PF00183.13 KII88630.1 - 7.4e-254 843.0 27.3 8.9e-254 842.8 18.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KII88630.1 - 4.7e-11 42.3 0.0 9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KII88630.1 - 9.1e-11 41.5 0.2 9.1e-11 41.5 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 KII88630.1 - 2.7 7.3 19.5 0.081 12.2 8.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Herpes_US9 PF06072.6 KII88631.1 - 0.087 12.6 0.1 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Aminotran_5 PF00266.14 KII88633.1 - 3.8e-35 121.3 0.0 5.1e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_79n PF03662.9 KII88633.1 - 0.12 10.9 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain TRAPPC10 PF12584.3 KII88634.1 - 8e-29 100.0 0.0 1.5e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DEAD PF00270.24 KII88635.1 - 1.7e-47 161.0 0.0 2.9e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII88635.1 - 3.7e-28 97.2 0.0 7.6e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII88635.1 - 0.00028 20.7 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_7 PF03492.10 KII88636.1 - 0.083 11.6 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase TMEM238 PF15125.1 KII88636.1 - 0.12 12.2 1.7 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 TMEM238 protein family 2OG-FeII_Oxy_3 PF13640.1 KII88638.1 - 1.3e-07 32.0 0.0 2.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KII88638.1 - 3.2e-07 29.8 0.0 5.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KII88638.1 - 0.016 15.4 0.0 0.035 14.4 0.0 1.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily HPIH PF13323.1 KII88638.1 - 0.097 12.3 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain with HPIH motif Far-17a_AIG1 PF04750.9 KII88639.1 - 3.5e-37 127.5 5.5 3.9e-37 127.3 3.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein GST_N_3 PF13417.1 KII88641.1 - 6e-14 52.0 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII88641.1 - 1.1e-09 38.1 0.0 2.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII88641.1 - 5.3e-06 26.2 0.1 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII88641.1 - 2.3e-05 24.2 0.0 8.3e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII88641.1 - 0.0023 18.0 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FUN14 PF04930.10 KII88642.1 - 2.7e-18 66.0 0.9 2.7e-18 66.0 0.6 1.5 2 0 0 2 2 2 1 FUN14 family DNA_primase_lrg PF04104.9 KII88643.1 - 1.1e-84 283.7 0.0 1.8e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SNARE PF05739.14 KII88644.1 - 2.7e-14 52.5 1.4 2.7e-14 52.5 1.0 2.6 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 KII88644.1 - 8e-14 51.6 8.5 1.4e-13 50.8 1.8 2.4 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KII88644.1 - 9.3e-05 22.0 6.0 0.0039 16.7 0.9 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.5 KII88644.1 - 0.0017 17.8 0.7 0.051 13.1 0.0 2.5 2 0 0 2 2 2 1 Vitamin D binding protein, domain III Syntaxin_2 PF14523.1 KII88644.1 - 0.0057 16.6 8.6 0.0084 16.1 3.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Tweety PF04906.8 KII88644.1 - 0.011 14.1 4.8 0.12 10.8 0.2 2.3 2 1 0 2 2 2 0 Tweety Spectrin PF00435.16 KII88644.1 - 0.029 14.6 5.9 0.43 10.8 0.1 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF1268 PF06896.6 KII88644.1 - 0.032 14.5 0.5 0.072 13.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) LRR19-TM PF15176.1 KII88644.1 - 0.038 13.6 3.1 0.1 12.2 2.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF1469 PF07332.6 KII88644.1 - 0.049 13.3 2.0 0.12 12.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) FUSC PF04632.7 KII88644.1 - 0.27 9.6 1.9 0.38 9.1 1.0 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family HisKA PF00512.20 KII88644.1 - 0.3 11.1 3.7 3.8 7.5 0.2 3.2 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF4094 PF13334.1 KII88644.1 - 0.35 11.2 3.8 2.9 8.3 0.0 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF4094) Spc7 PF08317.6 KII88644.1 - 0.4 9.2 9.0 1.6 7.3 0.2 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Rifin_STEVOR PF02009.11 KII88644.1 - 0.72 9.4 8.1 0.6 9.7 3.6 2.0 1 1 1 2 2 2 0 Rifin/stevor family WXG100 PF06013.7 KII88644.1 - 0.97 9.4 8.2 3.9 7.5 0.1 3.5 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Ibs_toxin PF13956.1 KII88644.1 - 3.9 7.3 8.3 6.8 6.6 5.8 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Pox_A_type_inc PF04508.7 KII88644.1 - 8.1 6.5 6.2 3.7 7.5 0.6 2.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Lyase_1 PF00206.15 KII88645.1 - 4e-100 335.0 0.0 5.8e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KII88645.1 - 6.3e-28 96.6 0.1 1.3e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Cellulase PF00150.13 KII88646.1 - 2.1e-13 50.1 0.4 3.6e-13 49.3 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF755 PF05501.6 KII88646.1 - 0.29 11.1 8.2 0.56 10.2 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 KII88646.1 - 4.3 6.7 7.1 8.8 5.7 5.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ALG3 PF05208.8 KII88647.1 - 3.1e-119 398.5 12.1 3.6e-119 398.2 8.4 1.0 1 0 0 1 1 1 1 ALG3 protein MFS_1 PF07690.11 KII88648.1 - 1.5e-13 50.1 28.1 1.5e-13 50.1 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KII88648.1 - 1.7e-09 37.3 2.8 1.7e-09 37.3 2.0 2.1 3 0 0 3 3 3 1 Nodulin-like HEAT PF02985.17 KII88649.1 - 8.5e-22 75.2 7.9 2.1e-05 24.2 0.1 9.0 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 KII88649.1 - 6.4e-16 58.4 9.7 1.5e-06 28.3 0.3 7.5 6 1 2 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 KII88649.1 - 0.00058 20.2 28.1 0.031 14.7 0.5 8.1 6 4 2 8 8 8 4 HEAT-like repeat MARVEL PF01284.18 KII88650.1 - 1.6 8.5 15.4 2.4 7.9 10.7 1.2 1 0 0 1 1 1 0 Membrane-associating domain Aldo_ket_red PF00248.16 KII88651.1 - 1.6e-50 171.5 0.0 1.8e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Macro PF01661.16 KII88651.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Macro domain SNARE PF05739.14 KII88653.1 - 5.6e-12 45.1 2.6 5.6e-12 45.1 1.8 2.5 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 KII88653.1 - 6.9e-12 45.4 8.9 7.7e-12 45.2 1.3 2.6 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 KII88653.1 - 6.4e-06 26.1 15.4 1.3e-05 25.1 6.7 2.4 2 0 0 2 2 2 1 Syntaxin-like protein V-SNARE PF05008.10 KII88653.1 - 0.022 14.9 0.2 0.022 14.9 0.2 3.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Ferritin PF00210.19 KII88653.1 - 0.033 13.9 0.4 0.23 11.2 0.0 2.3 2 1 0 2 2 2 0 Ferritin-like domain FUSC PF04632.7 KII88653.1 - 0.061 11.7 8.5 0.052 11.9 4.9 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Med28 PF11594.3 KII88653.1 - 0.085 13.1 2.7 10 6.4 0.3 2.4 2 1 0 2 2 2 0 Mediator complex subunit 28 Allexi_40kDa PF05549.6 KII88653.1 - 0.25 10.5 7.1 0.095 11.9 1.1 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Herpes_US9 PF06072.6 KII88653.1 - 0.3 10.9 1.5 0.74 9.6 1.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MCPsignal PF00015.16 KII88653.1 - 0.45 10.0 14.4 0.04 13.4 1.4 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF479 PF04336.7 KII88653.1 - 1.3 9.1 5.2 14 5.8 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function, DUF479 BLOC1_2 PF10046.4 KII88653.1 - 3.8 7.7 7.7 1.3 9.1 0.3 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.4 KII88653.1 - 4.8 7.4 7.1 5.7 7.1 0.1 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CDP-OH_P_transf PF01066.16 KII88654.1 - 1.1e-19 70.5 2.8 1.1e-19 70.5 2.0 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase AAA PF00004.24 KII88655.1 - 8.8e-36 123.0 0.0 1.7e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII88655.1 - 9.2e-06 25.7 2.0 0.0021 18.0 0.0 3.7 2 1 2 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 KII88655.1 - 0.00014 22.6 0.0 0.00049 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII88655.1 - 0.00018 21.1 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KII88655.1 - 0.00033 20.3 0.0 0.0013 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KII88655.1 - 0.00057 20.0 0.0 0.016 15.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII88655.1 - 0.0032 17.1 0.1 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KII88655.1 - 0.009 15.8 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KII88655.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KII88655.1 - 0.026 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KII88655.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KII88655.1 - 0.037 14.3 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KII88655.1 - 0.051 12.6 0.0 0.051 12.6 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KII88655.1 - 0.053 12.4 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 KII88655.1 - 0.055 12.1 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KII88655.1 - 0.094 12.1 0.1 2.6 7.3 0.1 2.8 2 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KII88655.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 KII88655.1 - 0.23 11.1 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KII88655.1 - 0.3 9.7 0.0 0.45 9.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SMC_Nse1 PF07574.8 KII88656.1 - 1.8e-23 83.2 0.3 6.3e-20 71.6 0.1 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex DUF1348 PF07080.6 KII88657.1 - 2.7e-51 173.1 2.5 3.3e-51 172.8 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 KII88657.1 - 0.00018 21.8 0.5 0.00035 20.9 0.4 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KII88657.1 - 0.0004 20.5 0.1 0.00064 19.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3648 PF12364.3 KII88657.1 - 0.042 13.8 0.1 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) Pectate_lyase_3 PF12708.2 KII88660.1 - 6.3e-83 278.3 25.4 2.8e-66 223.8 10.1 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KII88660.1 - 1.6e-08 33.9 2.5 0.0029 17.0 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Pectate_lyase_3 PF12708.2 KII88661.1 - 1.1e-82 277.5 19.3 1.6e-67 227.9 6.7 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KII88661.1 - 2.3e-07 30.1 1.6 0.021 14.3 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase CDC45 PF02724.9 KII88662.1 - 5.9e-179 596.0 0.0 6.6e-179 595.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Scramblase PF03803.10 KII88665.1 - 9.4e-57 191.6 0.0 4.3e-56 189.4 0.0 1.8 1 1 0 1 1 1 1 Scramblase GTP_EFTU PF00009.22 KII88666.1 - 6.3e-39 133.3 1.6 4.7e-38 130.4 1.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KII88666.1 - 1.4e-25 89.2 2.0 5.4e-25 87.3 0.4 2.6 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KII88666.1 - 1.6e-06 28.0 0.3 6.3e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KII88666.1 - 0.00025 21.0 6.3 0.014 15.5 0.1 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KII88666.1 - 0.00026 20.5 2.6 0.067 12.6 0.1 2.8 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KII88666.1 - 0.00057 20.3 0.1 0.0017 18.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KII88666.1 - 0.01 15.0 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CHORD PF04968.7 KII88667.1 - 9.1e-49 163.5 12.5 1.5e-24 85.9 2.8 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 KII88667.1 - 1.9e-15 57.1 0.0 4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 CS domain Rieske PF00355.21 KII88667.1 - 0.057 12.9 1.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain BTK PF00779.14 KII88667.1 - 0.25 10.9 6.1 8.4 6.1 0.0 3.5 3 0 0 3 3 3 0 BTK motif Mito_carr PF00153.22 KII88668.1 - 4e-13 48.8 0.0 0.00053 19.6 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.1 KII88669.1 - 4.7e-13 49.4 0.0 6.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.10 KII88669.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase LysR_substrate PF03466.15 KII88669.1 - 0.065 12.3 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DUF1776 PF08643.5 KII88670.1 - 0.0061 15.7 0.0 0.6 9.1 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KII88670.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding WD40 PF00400.27 KII88672.1 - 5.6e-48 159.1 16.6 1.2e-12 47.1 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Gmad1 PF10647.4 KII88672.1 - 8.1e-06 25.4 0.0 8.2e-05 22.1 0.0 2.4 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KII88672.1 - 5.4e-05 21.5 3.4 1.2 7.1 0.0 4.1 2 2 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII88672.1 - 0.00013 20.8 2.3 0.027 13.2 0.1 3.9 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.6 KII88672.1 - 0.0016 17.7 0.2 1.8 7.7 0.0 3.1 3 1 1 4 4 4 2 TUP1-like enhancer of split DUF3312 PF11768.3 KII88672.1 - 0.081 11.1 0.0 0.13 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Glu_synthase PF01645.12 KII88674.1 - 1.8e-158 527.3 1.0 2e-158 527.1 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KII88674.1 - 3.2e-138 460.3 0.0 4.3e-138 459.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KII88674.1 - 9.2e-115 382.8 0.0 1.5e-114 382.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KII88674.1 - 3.1e-69 232.0 3.3 7.5e-69 230.7 2.3 1.6 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KII88674.1 - 5.9e-24 83.8 0.1 1.3e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KII88674.1 - 3.6e-19 69.4 0.0 1e-18 67.9 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII88674.1 - 3.5e-12 46.8 0.1 5.7e-05 23.2 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII88674.1 - 4.4e-09 36.2 0.0 2.2e-08 33.9 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KII88674.1 - 9.9e-09 35.4 0.1 8.7e-05 22.8 0.0 3.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII88674.1 - 3.4e-06 25.8 1.1 5.6e-06 25.0 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KII88674.1 - 1.1e-05 24.5 0.1 0.00034 19.5 0.0 2.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KII88674.1 - 1.1e-05 24.5 4.2 6.3e-05 22.0 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII88674.1 - 9.1e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 KII88674.1 - 0.0017 18.5 0.8 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KII88674.1 - 0.0024 16.9 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.13 KII88674.1 - 0.0032 16.3 2.2 0.017 13.9 1.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_oxidored PF12831.2 KII88674.1 - 0.0035 16.4 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KII88674.1 - 0.0064 15.6 1.4 0.0087 15.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 KII88674.1 - 0.0082 15.8 0.1 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KII88674.1 - 0.011 14.7 0.6 0.52 9.1 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.16 KII88674.1 - 0.015 15.1 0.4 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 KII88674.1 - 0.017 14.7 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.14 KII88674.1 - 0.018 13.2 0.1 5.5 5.0 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_2 PF03446.10 KII88674.1 - 0.019 14.8 0.1 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.1 KII88674.1 - 0.031 14.0 0.3 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding GATase_6 PF13522.1 KII88674.1 - 0.041 13.8 0.3 0.15 12.0 0.1 2.0 2 0 0 2 2 1 0 Glutamine amidotransferase domain 3HCDH_N PF02737.13 KII88674.1 - 0.051 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KII88674.1 - 0.068 12.6 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KII88674.1 - 0.069 12.5 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KII88674.1 - 0.071 12.2 0.0 0.3 10.1 0.0 2.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KII88674.1 - 0.081 11.7 1.8 0.31 9.8 0.1 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KII88674.1 - 0.12 12.4 0.5 22 5.1 0.0 3.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4231 PF14015.1 KII88675.1 - 1.7 8.6 8.7 2.5 8.1 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Acetyltransf_13 PF13880.1 KII88677.1 - 7.8e-11 41.5 0.0 1.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KII88677.1 - 2.8e-07 29.9 0.1 4.1e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 KII88677.1 - 0.056 13.4 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family zf-Mss51 PF13824.1 KII88679.1 - 6.6e-23 80.3 12.8 1.1e-22 79.5 8.9 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 KII88679.1 - 0.016 15.4 5.7 0.032 14.5 3.9 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF1610 PF07754.6 KII88679.1 - 0.17 12.0 0.3 0.17 12.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) IGPD PF00475.13 KII88680.1 - 1.9e-59 199.6 0.1 2.7e-59 199.1 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase 3-HAO PF06052.7 KII88682.1 - 2.7e-59 198.8 0.0 3.1e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KII88682.1 - 1.5e-06 27.5 0.1 2.9e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KII88682.1 - 0.00037 20.2 0.1 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KII88682.1 - 0.0093 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Peptidase_M13_N PF05649.8 KII88684.1 - 2e-89 300.4 0.0 5.4e-89 298.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 KII88684.1 - 4e-53 179.6 0.0 7.1e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Mucin PF01456.12 KII88684.1 - 0.00085 19.1 13.6 0.0017 18.1 9.4 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein 2OG-FeII_Oxy_2 PF13532.1 KII88685.1 - 1.4e-25 90.3 0.0 2e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_8 PF02954.14 KII88685.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Peptidase_M24 PF00557.19 KII88686.1 - 9.8e-43 146.1 1.0 4.7e-42 143.9 0.3 2.0 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KII88686.1 - 6.9e-05 23.3 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain HAD_2 PF13419.1 KII88688.1 - 1.3e-16 61.3 0.0 2.2e-15 57.2 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII88688.1 - 1.5e-05 24.6 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 KII88688.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Hydrolase PF00702.21 KII88688.1 - 0.06 13.7 0.0 0.52 10.6 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase QCR10 PF09796.4 KII88689.1 - 5e-16 58.1 0.0 5.7e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) IMS_HHH PF11798.3 KII88689.1 - 0.11 12.5 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 IMS family HHH motif UCR_6-4kD PF08997.5 KII88689.1 - 0.22 11.2 1.5 0.4 10.4 1.1 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Nop16 PF09420.5 KII88690.1 - 5.6e-40 137.1 0.0 7.5e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zn_clus PF00172.13 KII88691.1 - 4e-06 26.6 4.3 8.4e-06 25.5 2.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KII88692.1 - 3.5e-68 229.9 0.0 5.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme EF-hand_1 PF00036.27 KII88693.1 - 4.8e-23 78.6 0.0 7.3e-06 24.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KII88693.1 - 7.5e-19 65.8 0.4 1.2e-05 24.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KII88693.1 - 1.5e-17 63.4 0.0 2.5e-08 33.9 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KII88693.1 - 5.1e-17 60.3 0.1 0.0002 20.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KII88693.1 - 4.2e-13 48.7 0.6 3.5e-05 23.3 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain pair F-box-like PF12937.2 KII88694.1 - 2e-08 33.8 1.1 9.7e-08 31.6 0.7 2.3 1 0 0 1 1 1 1 F-box-like DUF484 PF04340.7 KII88694.1 - 0.044 13.2 0.3 0.075 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 F_bP_aldolase PF01116.15 KII88695.1 - 4.4e-99 331.2 0.0 4.9e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.12 KII88695.1 - 0.13 11.5 0.4 0.34 10.1 0.2 1.7 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AdoHcyase PF05221.12 KII88695.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase dCMP_cyt_deam_1 PF00383.17 KII88696.1 - 4e-18 64.9 0.0 6e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KII88696.1 - 0.0047 16.7 0.7 0.19 11.5 0.5 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 KII88696.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 2 0 0 2 2 2 0 APOBEC-like N-terminal domain Transp_cyt_pur PF02133.10 KII88697.1 - 9.1e-43 146.4 35.7 1.2e-42 146.0 24.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Oxidored_q2 PF00420.19 KII88697.1 - 9.5 5.8 18.7 2.7 7.6 2.5 2.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L AMP-binding PF00501.23 KII88699.1 - 1.3e-79 267.5 0.0 1.7e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 KII88700.1 - 6.2e-31 107.3 25.9 6.2e-31 107.3 18.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII88700.1 - 2.8e-09 36.0 11.0 2.8e-09 36.0 7.6 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter VQ PF05678.9 KII88700.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 VQ motif Het-C PF07217.6 KII88700.1 - 0.26 9.4 0.0 0.38 8.8 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C SOR_SNZ PF01680.12 KII88702.1 - 4.8e-112 372.6 5.0 7.5e-112 371.9 3.5 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KII88702.1 - 7.3e-09 35.0 7.4 2.5e-07 30.0 0.1 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KII88702.1 - 4.6e-05 22.4 0.3 0.089 11.6 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KII88702.1 - 0.0022 17.2 0.5 0.11 11.6 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 KII88702.1 - 0.0024 16.9 0.1 0.015 14.3 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 KII88702.1 - 0.0031 16.7 5.4 0.013 14.7 0.1 2.4 2 0 0 2 2 2 1 Nitronate monooxygenase NanE PF04131.9 KII88702.1 - 0.0043 16.0 0.3 0.17 10.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF2984 PF11203.3 KII88702.1 - 0.15 12.1 2.7 0.51 10.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) Img2 PF05046.9 KII88704.1 - 1.3e-17 63.8 0.0 1.6e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.12 KII88705.1 - 1.1e-52 178.8 0.0 1.8e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KII88705.1 - 2e-14 52.6 0.0 5e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Ras PF00071.17 KII88706.1 - 2.6e-65 218.7 1.3 3.1e-65 218.5 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII88706.1 - 3.3e-21 75.9 0.0 5.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII88706.1 - 2.6e-17 62.6 0.3 3.2e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII88706.1 - 4.8e-07 29.1 0.1 5.8e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KII88706.1 - 1.1e-06 28.1 0.3 2.4e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KII88706.1 - 9.6e-06 24.9 0.1 1.2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KII88706.1 - 2.6e-05 24.1 0.1 4.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KII88706.1 - 0.00075 18.7 0.3 0.053 12.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KII88706.1 - 0.00094 19.3 0.0 0.0018 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KII88706.1 - 0.0036 17.5 0.1 0.34 11.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 KII88706.1 - 0.0061 15.8 0.1 0.032 13.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 KII88706.1 - 0.014 15.3 0.2 0.053 13.5 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KII88706.1 - 0.031 13.8 0.6 0.083 12.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KII88706.1 - 0.032 13.9 0.0 0.063 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KII88706.1 - 0.035 13.9 0.2 0.19 11.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KII88706.1 - 0.062 13.6 0.0 0.098 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 KII88706.1 - 0.07 12.1 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KII88706.1 - 0.089 12.2 0.1 1.1 8.7 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.18 KII88707.1 - 1e-29 103.8 0.0 2.1e-29 102.7 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Zn_Tnp_IS1595 PF12760.2 KII88708.1 - 0.024 14.4 1.0 0.079 12.7 0.7 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain efb-c PF12199.3 KII88709.1 - 0.14 12.0 0.2 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Cyclin_N PF00134.18 KII88710.1 - 3.5e-09 36.2 0.0 6.9e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Got1 PF04178.7 KII88711.1 - 5.5e-23 81.3 20.5 7.6e-23 80.8 14.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family LHC PF00556.15 KII88711.1 - 0.24 11.3 2.9 1 9.2 0.3 2.9 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit LigB PF02900.13 KII88713.1 - 2.5e-45 154.6 0.0 3.2e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Herpes_LP PF03363.8 KII88713.1 - 0.45 10.0 2.4 0.75 9.3 1.7 1.2 1 0 0 1 1 1 0 Herpesvirus leader protein Pkinase PF00069.20 KII88714.1 - 5.5e-63 212.5 0.0 6.6e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88714.1 - 3.5e-29 101.6 0.0 4.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII88714.1 - 0.0004 19.4 0.0 0.00083 18.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Brix PF04427.13 KII88715.1 - 1.1e-44 152.4 0.0 1.4e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Nop25 PF09805.4 KII88715.1 - 0.19 11.7 25.6 0.36 10.9 17.8 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Drc1-Sld2 PF11719.3 KII88715.1 - 0.2 10.7 11.0 0.36 9.8 7.6 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Cyto_heme_lyase PF01265.12 KII88716.1 - 1.4e-74 250.9 0.0 1.9e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase MAT1 PF06391.8 KII88717.1 - 5.5e-49 166.4 10.0 6.8e-49 166.1 7.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KII88717.1 - 3.1e-05 23.5 8.4 9.3e-05 22.0 5.9 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII88717.1 - 5.4e-05 22.7 6.1 0.00012 21.7 4.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII88717.1 - 7e-05 22.4 7.9 0.00022 20.8 5.7 1.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII88717.1 - 0.00027 20.8 7.5 0.00085 19.2 5.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII88717.1 - 0.0004 20.1 8.3 0.00095 18.9 5.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII88717.1 - 0.0054 16.8 2.6 0.0094 16.0 1.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KII88717.1 - 0.34 10.7 1.8 0.62 9.9 1.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glutaredoxin PF00462.19 KII88717.1 - 0.42 10.6 2.3 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin zf-RING_4 PF14570.1 KII88717.1 - 0.42 10.2 8.9 3.7 7.2 6.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KII88717.1 - 1.4 8.8 6.5 6.2 6.7 4.8 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Peptidase_C78 PF07910.8 KII88718.1 - 2.5e-41 141.1 0.0 4.6e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Proteasome PF00227.21 KII88719.1 - 3.2e-59 199.4 0.0 4.3e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII88719.1 - 3.4e-14 51.8 1.5 4.2e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SRP54 PF00448.17 KII88720.1 - 1.1e-46 158.7 0.1 5.5e-46 156.4 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KII88720.1 - 4e-45 154.3 0.2 1.3e-44 152.6 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 KII88720.1 - 5.4e-07 29.2 0.0 1.3e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 KII88720.1 - 4.7e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KII88720.1 - 3.4e-05 22.7 0.1 9e-05 21.3 0.1 1.6 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 KII88720.1 - 0.0031 17.2 0.0 0.0097 15.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KII88720.1 - 0.012 15.8 0.1 0.061 13.4 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.1 KII88720.1 - 0.032 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 KII88720.1 - 0.034 13.1 0.7 1.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.13 KII88720.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family WD40 PF00400.27 KII88721.1 - 3.3e-28 96.4 10.0 5.9e-13 48.1 0.2 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KII88721.1 - 0.0021 16.8 1.3 2.4 6.8 0.1 3.7 2 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 KII88721.1 - 0.0094 14.1 1.9 0.42 8.6 0.4 2.9 2 1 0 2 2 2 1 Nucleoporin Nup120/160 DUF3445 PF11927.3 KII88722.1 - 2e-68 230.4 0.0 2.7e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ApoO PF09769.4 KII88722.1 - 0.056 13.1 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O NMO PF03060.10 KII88723.1 - 6e-74 249.1 0.9 7.1e-74 248.8 0.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KII88723.1 - 3e-07 29.6 0.3 0.016 14.1 0.2 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KII88723.1 - 0.029 13.2 3.7 0.049 12.4 2.6 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TPR_14 PF13428.1 KII88726.1 - 1.9e-08 34.2 11.1 5.5 7.9 0.0 10.0 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII88726.1 - 3.5e-08 32.9 10.8 0.38 10.4 0.0 7.3 8 0 0 8 8 8 2 TPR repeat TPR_12 PF13424.1 KII88726.1 - 8.1e-07 28.8 5.1 0.62 10.0 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII88726.1 - 2.1e-06 27.2 13.2 0.052 13.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat NRDE-2 PF08424.5 KII88726.1 - 3.3e-06 26.2 1.0 0.19 10.6 0.0 4.1 2 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 KII88726.1 - 3.7e-06 27.1 3.8 4.2 7.7 0.1 5.7 5 1 0 6 6 6 3 Tetratricopeptide repeat Suf PF05843.9 KII88726.1 - 1.4e-05 25.0 5.6 0.00082 19.1 0.1 4.9 4 1 2 6 6 6 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.7 KII88726.1 - 0.0081 15.9 8.7 5.9 6.6 0.1 5.9 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 HAT PF02184.11 KII88726.1 - 3.6 7.4 12.3 2.3 8.0 0.0 5.5 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat PPTA PF01239.17 KII88727.1 - 1.5e-40 134.8 10.7 5.4e-10 38.1 0.3 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Lactamase_B PF00753.22 KII88728.1 - 5.4e-21 75.1 2.0 7.5e-21 74.6 1.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF347 PF03988.7 KII88729.1 - 0.054 13.3 0.8 0.1 12.5 0.5 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TMEM154 PF15102.1 KII88729.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.1 KII88729.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3329 PF11808.3 KII88729.1 - 0.18 11.8 0.2 0.98 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Tad PF13400.1 KII88729.1 - 0.24 11.4 2.6 0.35 10.9 1.8 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Sec7 PF01369.15 KII88730.1 - 2e-61 207.0 0.0 3.2e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KII88730.1 - 2e-20 72.9 0.9 2.7e-09 36.6 0.1 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KII88730.1 - 0.0024 17.3 1.3 0.89 9.1 0.0 4.3 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Cytochrom_B561 PF03188.11 KII88731.1 - 7.3e-12 45.2 10.3 1.4e-11 44.3 6.5 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 KII88731.1 - 0.0047 16.6 0.7 0.0047 16.6 0.5 3.7 5 0 0 5 5 5 1 PepSY-associated TM helix NYN PF01936.13 KII88733.1 - 4e-15 56.3 0.1 7.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 NYN domain adh_short PF00106.20 KII88734.1 - 3.6e-24 85.5 0.6 5e-24 85.0 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII88734.1 - 5.5e-24 85.2 0.0 7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII88734.1 - 8.1e-13 48.4 0.2 1.3e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 KII88736.1 - 3.6e-38 128.0 15.5 8.6e-12 44.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sulfate_transp PF00916.15 KII88737.1 - 3.3e-78 262.5 8.7 5.4e-78 261.8 6.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KII88737.1 - 5.5e-32 109.2 5.2 5.5e-32 109.2 3.6 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KII88737.1 - 1.3e-08 34.2 0.0 2.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KII88737.1 - 0.0074 16.3 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain F-box-like PF12937.2 KII88738.1 - 0.0033 17.1 0.0 0.017 14.8 0.0 2.3 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.12 KII88740.1 - 1.4e-46 158.7 0.0 1.5e-28 99.5 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KII88740.1 - 4.9e-40 137.3 0.0 1.2e-39 136.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII88740.1 - 0.00083 19.1 0.4 0.0035 17.0 0.0 2.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII88740.1 - 0.0025 16.8 0.0 0.34 9.8 0.0 2.2 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII88740.1 - 0.011 15.0 0.0 0.076 12.3 0.0 1.9 1 1 1 2 2 2 0 RIO1 family PIN_4 PF13638.1 KII88741.1 - 6.9e-22 77.9 0.2 1.6e-21 76.7 0.2 1.7 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 KII88741.1 - 5.5e-12 45.4 0.0 5e-11 42.3 0.0 2.5 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Cytochrom_B561 PF03188.11 KII88742.1 - 1.7e-07 31.1 7.6 2.9e-07 30.4 5.3 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KII88742.1 - 1.8e-05 24.6 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DOMON domain PIG-Y PF15159.1 KII88742.1 - 0.71 10.1 4.0 0.35 11.1 0.5 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y NDK PF00334.14 KII88743.1 - 2.8e-56 189.0 0.0 3.2e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KII88743.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ UCR_14kD PF02271.11 KII88744.1 - 1e-36 124.9 1.7 1.2e-36 124.6 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.16 KII88745.1 - 3e-139 463.4 0.1 3.9e-139 463.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KII88745.1 - 4.2e-41 140.3 0.0 1.2e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KII88745.1 - 2.7e-13 49.9 0.0 7.2e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KII88745.1 - 2.1e-05 23.5 0.2 4.2e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KII88745.1 - 0.00035 19.4 0.0 0.0006 18.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Cmc1 PF08583.5 KII88746.1 - 1e-13 50.8 1.9 1.2e-13 50.5 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KII88746.1 - 0.026 14.4 3.5 0.42 10.5 0.2 2.2 2 0 0 2 2 2 0 CHCH domain MFS_1 PF07690.11 KII88748.1 - 3.4e-29 101.6 63.2 4.7e-15 55.1 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII88748.1 - 0.00044 18.9 40.9 0.0054 15.3 11.8 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter PALP PF00291.20 KII88749.1 - 8.8e-48 163.0 0.0 1.2e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.16 KII88749.1 - 0.00023 20.7 0.2 0.00043 19.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.10 KII88749.1 - 0.0034 17.0 0.1 0.0064 16.1 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FAD_binding_2 PF00890.19 KII88749.1 - 0.12 11.1 0.5 0.23 10.2 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain PALP PF00291.20 KII88750.1 - 1.1e-54 185.8 0.0 1.3e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.16 KII88750.1 - 0.0013 18.2 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TP_methylase PF00590.15 KII88750.1 - 0.0097 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2346 PF09803.4 KII88751.1 - 4.6e-11 42.4 0.4 7e-11 41.8 0.2 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Pyridoxal_deC PF00282.14 KII88753.1 - 9.7e-57 192.0 0.0 1.3e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KII88753.1 - 4.9e-05 22.2 0.0 7.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 KII88753.1 - 0.053 12.0 0.0 0.089 11.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Copper-bind PF00127.15 KII88755.1 - 0.00023 21.3 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Hid1 PF12722.2 KII88756.1 - 5.2e-154 514.1 0.0 8.6e-154 513.4 0.0 1.2 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KII88756.1 - 1.5e-70 238.1 0.0 2.1e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MCPVI PF02993.9 KII88756.1 - 0.023 14.8 2.6 0.04 14.0 1.8 1.3 1 0 0 1 1 1 0 Minor capsid protein VI MFS_1 PF07690.11 KII88757.1 - 5.8e-24 84.4 74.7 7.6e-21 74.1 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 KII88758.1 - 5.7e-08 32.3 2.1 1.8e-07 30.7 1.5 1.9 1 0 0 1 1 1 1 F-box-like DivIC PF04977.10 KII88758.1 - 0.043 13.3 1.0 0.085 12.3 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2857 PF11198.3 KII88758.1 - 0.059 12.8 0.2 1.1 8.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2857) DUF4349 PF14257.1 KII88758.1 - 0.091 11.9 2.5 0.14 11.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GAS PF13851.1 KII88758.1 - 0.24 10.5 0.2 0.36 9.9 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rad51 PF08423.6 KII88759.1 - 1.4e-18 66.7 0.0 2.8e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KII88759.1 - 4.4e-05 22.9 0.1 0.0013 18.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain RecA PF00154.16 KII88759.1 - 0.00099 18.2 0.1 0.0019 17.3 0.1 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KII88759.1 - 0.033 13.3 0.3 0.15 11.1 0.1 1.9 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.10 KII88759.1 - 0.036 12.9 0.2 0.084 11.7 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TarH PF02203.10 KII88759.1 - 0.36 10.6 2.7 0.33 10.7 0.1 2.1 3 0 0 3 3 3 0 Tar ligand binding domain homologue MFS_1 PF07690.11 KII88761.1 - 5.9e-40 137.0 36.9 5.9e-40 137.0 25.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KII88761.1 - 0.00053 18.3 1.7 0.00081 17.7 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glt_symporter PF03616.9 KII88761.1 - 0.041 12.3 2.5 0.075 11.5 1.7 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter MFS_1 PF07690.11 KII88762.1 - 6.1e-38 130.4 37.1 6.1e-38 130.4 25.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Glt_symporter PF03616.9 KII88762.1 - 0.18 10.2 4.4 0.37 9.2 3.0 1.5 1 0 0 1 1 1 0 Sodium/glutamate symporter Lactamase_B_2 PF12706.2 KII88763.1 - 7.9e-19 67.9 0.0 1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KII88763.1 - 4.4e-08 33.0 0.1 1.5e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 KII88763.1 - 0.0049 15.8 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Glyco_hydro_63 PF03200.11 KII88765.1 - 1e-233 777.7 0.0 8.1e-233 774.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 KII88765.1 - 0.00069 18.4 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KII88765.1 - 0.0025 16.5 0.1 0.0041 15.8 0.0 1.2 1 0 0 1 1 1 1 Trehalase Band_7 PF01145.20 KII88766.1 - 2.4e-06 27.6 0.6 2.4e-06 27.6 0.4 2.7 2 1 1 3 3 3 1 SPFH domain / Band 7 family PIH1 PF08190.7 KII88766.1 - 0.02 14.3 1.2 0.029 13.8 0.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 UPF0104 PF03706.8 KII88767.1 - 0.056 12.7 4.4 0.092 12.0 3.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF2417 PF10329.4 KII88767.1 - 0.081 12.3 2.2 0.12 11.7 1.5 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF4386 PF14329.1 KII88767.1 - 0.09 12.2 7.0 0.12 11.8 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) CRPA PF05745.6 KII88767.1 - 0.17 11.6 4.4 0.21 11.4 2.5 1.4 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF1761 PF08570.5 KII88767.1 - 0.19 11.7 6.7 12 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF4131 PF13567.1 KII88767.1 - 0.26 10.6 1.4 0.34 10.3 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 KII88767.1 - 0.55 10.2 7.5 0.57 10.1 4.6 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein AA_permease_2 PF13520.1 KII88767.1 - 0.73 8.2 10.1 0.54 8.7 6.1 1.3 1 1 0 1 1 1 0 Amino acid permease PAP2_C PF14360.1 KII88767.1 - 2.5 8.4 11.2 0.57 10.4 5.2 1.8 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Bax1-I PF01027.15 KII88767.1 - 7 6.1 12.8 2.5 7.6 5.5 1.9 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Optomotor-blind PF11078.3 KII88770.1 - 0.0015 18.8 0.6 0.0015 18.8 0.4 1.5 2 0 0 2 2 2 1 Optomotor-blind protein N-terminal region UBN2 PF14223.1 KII88772.1 - 4.5e-12 45.7 0.0 5e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII88772.1 - 2.2e-07 30.4 0.0 2.7e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KII88772.1 - 0.02 14.4 0.1 0.024 14.2 0.1 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1877 PF08974.5 KII88772.1 - 0.035 13.7 0.1 0.075 12.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) Atg8 PF02991.11 KII88773.1 - 4.1e-52 174.4 0.2 4.9e-52 174.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KII88773.1 - 3.3e-07 30.4 0.0 4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.12 KII88773.1 - 0.041 13.3 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Variant SH3 domain ubiquitin PF00240.18 KII88774.1 - 3.6e-21 74.3 0.0 9.3e-21 73.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KII88774.1 - 6.9e-11 41.6 0.0 1.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4_3 PF13920.1 KII88774.1 - 0.00047 19.7 8.7 0.00079 19.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII88774.1 - 0.013 15.2 10.2 0.022 14.4 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Ubiquitin_2 PF14560.1 KII88774.1 - 0.072 13.3 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain zf-C3HC4 PF00097.20 KII88774.1 - 0.33 10.6 7.0 0.71 9.5 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII88774.1 - 2.2 8.1 7.5 4.7 7.1 5.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KII88774.1 - 6.3 6.9 9.4 12 6.0 6.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KII88777.1 - 2.6e-61 207.0 0.0 3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88777.1 - 2.1e-24 85.9 0.0 3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII88777.1 - 1.7e-05 23.9 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII88777.1 - 0.0015 18.3 0.1 0.033 13.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII88777.1 - 0.0043 16.6 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.27 KII88778.1 - 1.5e-61 202.2 22.0 7.1e-09 35.2 0.1 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KII88778.1 - 9.5e-13 47.6 0.0 2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII88778.1 - 3.8e-11 42.3 0.0 8.4e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KII88778.1 - 7e-11 40.9 10.8 0.012 13.7 0.1 6.0 1 1 4 6 6 6 5 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KII88778.1 - 4.9e-05 23.0 0.0 7.9 6.2 0.0 4.9 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Pkinase_Tyr PF07714.12 KII88779.1 - 2.8e-44 151.1 0.0 5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII88779.1 - 7.1e-41 140.0 0.0 1.6e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 KII88779.1 - 2.9e-29 102.1 0.9 6.5e-29 101.0 0.6 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII88779.1 - 4.3e-12 46.0 0.1 1.2e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Kinase-like PF14531.1 KII88779.1 - 0.00084 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII88779.1 - 0.012 15.3 0.1 0.045 13.4 0.1 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.2 KII88780.1 - 9e-07 28.5 1.3 3.6e-06 26.5 0.9 2.2 1 0 0 1 1 1 1 F-box-like NPV_P10 PF05531.7 KII88780.1 - 0.0075 16.5 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF2520 PF10728.4 KII88780.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) LRR_4 PF12799.2 KII88780.1 - 0.016 14.8 0.4 17 5.1 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) RasGAP_C PF03836.10 KII88780.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RasGAP C-terminus SlyX PF04102.7 KII88780.1 - 0.18 12.1 0.9 0.44 10.9 0.6 1.6 1 0 0 1 1 1 0 SlyX bZIP_1 PF00170.16 KII88780.1 - 0.19 11.7 0.1 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor FAP PF07174.6 KII88782.1 - 0.22 10.7 10.8 0.27 10.4 7.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) COQ7 PF03232.8 KII88783.1 - 1e-65 220.3 0.0 1.2e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF3849 PF12960.2 KII88783.1 - 0.093 12.6 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) NDUF_B4 PF07225.7 KII88784.1 - 0.00056 19.7 0.0 0.00063 19.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.18 KII88785.1 - 6.2e-13 48.3 1.5 1.4e-12 47.2 1.1 1.6 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 KII88785.1 - 9.9e-13 47.8 0.0 2.1e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII88785.1 - 1.4e-12 47.0 0.1 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII88785.1 - 2.3e-06 27.3 0.3 0.043 13.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KII88785.1 - 7.2e-06 25.7 0.9 2.6e-05 23.9 0.6 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RED_N PF07808.8 KII88785.1 - 0.02 14.1 0.5 0.039 13.1 0.3 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_jaz PF12171.3 KII88785.1 - 0.048 13.8 0.6 0.098 12.8 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PBP PF01161.15 KII88786.1 - 5.8e-16 58.6 0.0 8.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4644 PF15486.1 KII88786.1 - 0.093 12.6 0.6 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) PAP2 PF01569.16 KII88787.1 - 8.4e-21 73.9 2.8 8.4e-21 73.9 2.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily FAM163 PF15069.1 KII88788.1 - 0.0046 17.5 0.0 0.0052 17.3 0.0 1.1 1 0 0 1 1 1 1 FAM163 family LRR19-TM PF15176.1 KII88788.1 - 0.041 13.5 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain IncA PF04156.9 KII88788.1 - 0.18 11.3 0.2 0.23 11.0 0.2 1.4 1 1 0 1 1 1 0 IncA protein FH2 PF02181.18 KII88789.1 - 2e-75 254.0 6.0 2e-75 254.0 4.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KII88789.1 - 4.3e-38 130.5 0.1 4.3e-38 130.5 0.1 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KII88789.1 - 4.7e-36 124.0 0.5 4.7e-36 124.0 0.3 2.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain XhlA PF10779.4 KII88789.1 - 4.9 7.1 9.2 0.78 9.6 0.6 3.6 2 0 0 2 2 2 0 Haemolysin XhlA COG4 PF08318.7 KII88790.1 - 1.8e-57 194.5 0.0 3.6e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein MutS_III PF05192.13 KII88790.1 - 0.0019 18.0 0.5 1.8 8.3 0.0 2.9 2 1 0 2 2 2 2 MutS domain III FUSC PF04632.7 KII88790.1 - 0.52 8.6 10.0 5 5.4 0.0 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family Snf7 PF03357.16 KII88791.1 - 9.5e-40 135.7 18.4 9.5e-40 135.7 12.8 1.6 2 0 0 2 2 2 1 Snf7 DUF939_C PF11728.3 KII88791.1 - 0.13 12.0 5.6 0.11 12.2 2.6 1.9 1 1 0 1 1 1 0 DUF939 C-terminal domain Pathogen_betaC1 PF09593.5 KII88791.1 - 0.26 11.0 1.8 0.45 10.2 1.2 1.3 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein V_ATPase_I PF01496.14 KII88791.1 - 0.36 8.6 4.7 0.45 8.2 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 KII88791.1 - 0.91 9.5 11.5 2.1 8.4 4.0 2.1 1 1 1 2 2 2 0 YlqD protein zf-AN1 PF01428.11 KII88792.1 - 1.7e-18 66.1 18.5 4.4e-09 36.0 5.1 2.5 2 1 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KII88792.1 - 0.045 13.9 12.4 0.13 12.4 2.2 2.6 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Myosin_head PF00063.16 KII88793.1 - 5.9e-240 798.0 0.1 1.4e-239 796.7 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KII88793.1 - 9.7e-34 115.4 7.7 1.6e-33 114.7 1.6 2.9 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 KII88793.1 - 3.5e-10 38.5 41.8 0.015 14.9 0.9 7.3 7 0 0 7 7 7 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KII88793.1 - 0.014 15.4 2.3 0.082 13.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain TMF_DNA_bd PF12329.3 KII88793.1 - 0.045 13.5 23.3 0.011 15.5 3.9 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pcc1 PF09341.5 KII88793.1 - 0.18 11.8 4.4 1.4 9.0 0.1 3.7 3 0 0 3 3 3 0 Transcription factor Pcc1 MutS_III PF05192.13 KII88793.1 - 0.8 9.4 10.5 2.7 7.7 7.3 1.9 1 0 0 1 1 1 0 MutS domain III CENP-F_leu_zip PF10473.4 KII88793.1 - 1.7 8.5 25.3 0.15 11.9 9.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-O PF09496.5 KII88793.1 - 1.7 8.9 6.5 1.4 9.1 0.7 3.3 3 0 0 3 3 3 0 Cenp-O kinetochore centromere component DUF342 PF03961.8 KII88793.1 - 2 6.7 11.1 3.6 5.9 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KII88793.1 - 8.8 6.4 17.6 0.45 10.6 7.4 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2422 PF10337.4 KII88794.1 - 2.1e-13 49.9 16.3 8.6e-05 21.5 1.2 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KII88794.1 - 2.8e-12 46.6 11.6 2.8e-12 46.6 8.1 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KII88794.1 - 8.5e-08 31.2 24.6 7.4e-06 24.8 5.0 3.7 3 1 0 3 3 3 2 Aluminium activated malate transporter DUF2421 PF10334.4 KII88794.1 - 3e-06 27.0 1.9 3.4e-06 26.8 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) Uds1 PF15456.1 KII88794.1 - 0.089 12.7 5.9 0.42 10.6 0.2 3.3 2 1 0 2 2 2 0 Up-regulated During Septation Fungal_trans PF04082.13 KII88798.1 - 1.1e-20 73.5 0.1 1.1e-20 73.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII88798.1 - 2.2e-05 24.2 12.0 5.3e-05 23.0 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KII88799.1 - 1.2e-05 24.9 2.3 7.8e-05 22.4 0.1 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat SKG6 PF08693.5 KII88800.1 - 0.089 12.1 1.4 0.43 9.9 0.3 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ADK PF00406.17 KII88801.1 - 2.5e-45 154.0 1.3 1.5e-43 148.2 0.9 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KII88801.1 - 2.8e-06 27.6 0.0 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII88801.1 - 6.2e-06 26.1 0.2 4.2e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII88801.1 - 4e-05 24.4 0.0 7.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KII88801.1 - 0.0011 18.4 1.0 0.64 9.3 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 KII88801.1 - 0.049 12.7 0.1 0.24 10.4 0.0 2.1 2 1 0 2 2 2 0 Zeta toxin Alpha-2-MRAP_C PF06401.6 KII88801.1 - 0.066 13.0 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DAGK_cat PF00781.19 KII88802.1 - 7.8e-14 51.2 0.1 2.3e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Imm1 PF14430.1 KII88802.1 - 0.052 13.7 0.2 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm1 CN_hydrolase PF00795.17 KII88803.1 - 5.3e-31 107.4 0.0 6.9e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ PF00226.26 KII88804.1 - 3.8e-23 80.9 2.1 6.2e-23 80.3 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KII88804.1 - 4.4e-21 74.5 2.5 1.4e-18 66.5 0.1 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KII88804.1 - 1.9e-15 56.6 18.6 3.3e-15 55.8 12.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KII88804.1 - 0.23 11.1 10.5 0.81 9.4 1.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2340 PF10209.4 KII88805.1 - 4.8e-44 149.4 0.5 5.7e-44 149.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Glyco_hydro_3 PF00933.16 KII88806.1 - 2.3e-78 263.2 0.0 3.4e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII88806.1 - 2.2e-66 223.6 0.0 9.7e-66 221.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII88806.1 - 8.8e-21 73.6 0.0 1.7e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KII88806.1 - 4.8e-11 42.5 0.0 8.2e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.4 KII88806.1 - 0.011 14.4 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein adh_short PF00106.20 KII88807.1 - 3.5e-24 85.6 2.3 4.7e-24 85.1 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII88807.1 - 1.9e-09 37.6 0.5 2.9e-09 37.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII88807.1 - 6.3e-09 35.7 1.0 8.9e-09 35.2 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII88807.1 - 0.0017 18.3 0.1 0.0058 16.6 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 KII88807.1 - 0.008 15.7 0.1 0.025 14.1 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KII88807.1 - 0.012 15.0 0.1 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII88807.1 - 0.06 12.5 0.4 0.083 12.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KII88807.1 - 0.063 13.0 0.2 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 KII88807.1 - 0.079 11.9 0.2 0.15 10.9 0.1 1.5 1 1 1 2 2 2 0 Saccharopine dehydrogenase Bcl-2 PF00452.14 KII88808.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family SSI PF00720.12 KII88810.1 - 0.47 10.4 1.9 2.5 8.1 0.7 1.9 1 1 1 2 2 2 0 Subtilisin inhibitor-like Myb_Cef PF11831.3 KII88811.1 - 5.9e-61 205.6 0.1 5.9e-61 205.6 0.0 4.0 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KII88811.1 - 9.5e-20 70.3 3.8 1.9e-09 37.4 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII88811.1 - 1.8e-17 63.1 5.5 6.5e-12 45.3 1.3 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Shisa PF13908.1 KII88812.1 - 0.059 13.5 0.5 0.059 13.5 0.3 3.0 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF1690 PF07956.6 KII88813.1 - 3.5e-14 52.9 2.5 7.9e-14 51.8 1.8 1.6 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) LUC7 PF03194.10 KII88813.1 - 0.091 12.2 3.2 0.098 12.1 2.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DegS PF05384.6 KII88813.1 - 0.22 10.7 5.9 0.7 9.0 4.1 1.8 1 1 0 1 1 1 0 Sensor protein DegS AKNA PF12443.3 KII88813.1 - 0.35 10.9 3.7 1.8 8.6 2.4 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor PLAC9 PF15205.1 KII88813.1 - 0.44 10.8 1.9 0.58 10.4 0.2 1.9 1 1 1 2 2 2 0 Placenta-specific protein 9 APG6 PF04111.7 KII88813.1 - 1.4 7.9 8.9 2 7.3 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 OB_NTP_bind PF07717.11 KII88814.1 - 9.1e-19 67.3 0.0 1.8e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KII88814.1 - 1.5e-17 63.5 0.0 2.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KII88814.1 - 1e-13 50.9 0.0 2.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KII88814.1 - 3.6e-06 27.1 0.0 1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 KII88814.1 - 6.7e-06 25.7 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KII88814.1 - 0.0053 15.6 0.0 0.0095 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KII88814.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KII88814.1 - 0.011 15.5 0.1 0.25 11.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KII88814.1 - 0.094 13.0 0.1 0.43 10.8 0.0 2.1 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KII88814.1 - 0.097 11.7 0.1 0.29 10.1 0.0 1.8 1 1 1 2 2 2 0 Zeta toxin DUF572 PF04502.8 KII88815.1 - 3.6e-88 295.8 6.8 4.5e-88 295.5 4.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) HrpA_pilin PF09589.5 KII88815.1 - 0.0034 17.7 0.7 0.0076 16.6 0.0 1.9 2 1 0 2 2 2 1 HrpA pilus formation protein DUF866 PF05907.8 KII88815.1 - 0.0076 15.7 0.2 0.015 14.8 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 KII88815.1 - 0.14 11.8 1.4 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Lar_restr_allev PF14354.1 KII88815.1 - 0.18 12.0 0.9 7.1 7.0 1.1 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Mis14 PF08641.7 KII88816.1 - 7.2e-05 22.8 3.0 7.2e-05 22.8 2.1 1.9 2 1 0 2 2 2 1 Kinetochore protein Mis14 like BAG PF02179.11 KII88816.1 - 0.038 14.0 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 BAG domain Syntaxin-6_N PF09177.6 KII88816.1 - 0.64 10.4 4.4 0.35 11.2 0.6 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Gar1 PF04410.9 KII88817.1 - 2.2e-38 131.1 0.0 2.7e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.24 KII88818.1 - 7.9e-63 210.5 0.0 2.6e-44 150.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII88818.1 - 1.7e-08 34.6 2.3 0.0077 16.2 0.1 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KII88818.1 - 2.8e-07 31.3 0.0 0.0063 17.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KII88818.1 - 7.8e-06 25.1 0.0 0.0045 16.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KII88818.1 - 8.3e-06 25.5 0.2 0.018 14.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KII88818.1 - 4.1e-05 23.4 0.0 0.075 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KII88818.1 - 9.1e-05 22.6 0.2 0.0047 17.0 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KII88818.1 - 0.00037 19.9 2.2 0.0044 16.4 0.2 2.7 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KII88818.1 - 0.00062 19.2 0.1 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KII88818.1 - 0.00066 19.3 0.0 0.0049 16.5 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KII88818.1 - 0.0011 19.0 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.8 KII88818.1 - 0.0012 17.6 0.0 0.027 13.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 KII88818.1 - 0.0017 17.8 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KII88818.1 - 0.0026 18.0 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KII88818.1 - 0.0034 16.5 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_2 PF07724.9 KII88818.1 - 0.0046 16.8 0.0 0.017 15.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KII88818.1 - 0.0059 16.7 0.0 0.091 12.9 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KII88818.1 - 0.0061 16.4 0.0 0.17 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KII88818.1 - 0.0072 15.5 0.2 0.039 13.1 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KII88818.1 - 0.0088 14.9 0.0 0.87 8.4 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 KII88818.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KII88818.1 - 0.015 15.2 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KII88818.1 - 0.023 14.2 0.2 0.09 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KII88818.1 - 0.024 14.2 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KII88818.1 - 0.028 14.0 0.8 2.7 7.6 0.0 3.1 3 0 0 3 3 3 0 NACHT domain Vps4_C PF09336.5 KII88818.1 - 0.029 14.2 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PhoH PF02562.11 KII88818.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.17 KII88818.1 - 0.043 13.6 0.0 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 KII88818.1 - 0.16 11.6 0.1 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KII88818.1 - 0.2 10.7 0.0 0.45 9.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 KII88818.1 - 0.38 9.5 0.1 1.6 7.5 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain PhoD PF09423.5 KII88819.1 - 2.6e-48 164.7 2.2 1.8e-47 161.9 1.5 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase GalP_UDP_transf PF01087.17 KII88820.1 - 2e-59 200.7 0.0 3.2e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KII88820.1 - 1.9e-46 157.6 0.0 3.9e-46 156.6 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 KII88820.1 - 0.0025 18.0 0.3 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KII88820.1 - 0.012 16.1 0.6 0.11 12.9 0.2 2.7 3 1 0 3 3 3 0 HIT domain NUDIX PF00293.23 KII88821.1 - 8.7e-18 64.2 0.4 1.5e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 NUDIX domain Phage_integrase PF00589.17 KII88827.1 - 5.5e-05 22.9 0.5 0.0015 18.2 0.0 2.8 3 0 0 3 3 3 1 Phage integrase family PLRV_ORF5 PF01690.12 KII88829.1 - 0.21 10.7 4.6 0.28 10.2 3.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4219 PF13961.1 KII88834.1 - 3.8e-07 29.3 1.4 4.7e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 KII88834.1 - 1.6e-05 24.5 0.1 2e-05 24.1 0.1 1.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Ctr PF04145.10 KII88837.1 - 2.3 8.2 4.4 0.84 9.6 0.1 2.6 2 2 0 2 2 2 0 Ctr copper transporter family AraC_binding PF02311.14 KII88841.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.6 KII88841.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Chromo PF00385.19 KII88842.1 - 3.5e-12 45.8 0.0 3.7e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TMF_DNA_bd PF12329.3 KII88844.1 - 0.00081 19.1 2.1 0.00081 19.1 1.5 1.5 2 0 0 2 2 1 1 TATA element modulatory factor 1 DNA binding DUF2353 PF09789.4 KII88844.1 - 0.0034 16.6 1.9 0.0038 16.5 1.3 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.6 KII88844.1 - 0.004 16.9 1.8 0.0051 16.6 1.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KII88844.1 - 0.0045 16.8 1.5 0.0066 16.3 1.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KII88844.1 - 0.0052 16.4 3.5 0.0053 16.3 1.9 1.3 1 1 0 1 1 1 1 IncA protein FlaC_arch PF05377.6 KII88844.1 - 0.014 15.2 0.4 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DASH_Spc34 PF08657.5 KII88844.1 - 0.014 15.0 4.9 0.041 13.5 3.4 1.8 1 1 0 1 1 1 0 DASH complex subunit Spc34 GAS PF13851.1 KII88844.1 - 0.016 14.4 1.4 0.022 13.9 1.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 KII88844.1 - 0.02 14.8 2.3 0.02 14.8 1.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor BRE1 PF08647.6 KII88844.1 - 0.021 14.7 1.3 0.034 14.1 0.9 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.4 KII88844.1 - 0.023 13.6 5.2 0.031 13.2 3.6 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 KII88844.1 - 0.03 14.6 1.6 0.064 13.5 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 KII88844.1 - 0.03 13.7 1.8 0.068 12.6 1.2 1.6 1 1 0 1 1 1 0 Septum formation initiator KLRAQ PF10205.4 KII88844.1 - 0.034 14.1 1.2 0.034 14.1 0.8 1.5 2 0 0 2 2 1 0 Predicted coiled-coil domain-containing protein DUF2228 PF10228.4 KII88844.1 - 0.035 13.6 0.4 0.041 13.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) CorA PF01544.13 KII88844.1 - 0.038 13.0 0.2 0.047 12.7 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mod_r PF07200.8 KII88844.1 - 0.043 13.7 0.6 0.066 13.1 0.1 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.1 KII88844.1 - 0.059 13.3 1.7 0.11 12.4 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.15 KII88844.1 - 0.082 12.6 1.6 0.14 11.9 1.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Spc24 PF08286.6 KII88844.1 - 0.087 12.5 1.8 0.17 11.5 1.3 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 COG2 PF06148.6 KII88844.1 - 0.095 12.5 0.2 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF521 PF04412.8 KII88844.1 - 0.13 10.7 0.1 0.15 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) APG6 PF04111.7 KII88844.1 - 0.13 11.2 1.6 0.14 11.1 1.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Microtub_assoc PF07989.6 KII88844.1 - 0.2 11.5 2.1 0.33 10.8 1.5 1.4 1 0 0 1 1 1 0 Microtubule associated bZIP_2 PF07716.10 KII88844.1 - 3.2 7.6 6.8 0.15 11.8 0.6 1.9 2 0 0 2 2 1 0 Basic region leucine zipper Cauli_VI PF01693.11 KII88850.1 - 1.7e-21 75.9 0.6 8.6e-12 44.8 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin Gpi1 PF05024.10 KII88851.1 - 8.1e-46 156.0 7.3 1.5e-45 155.1 5.1 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.17 KII88852.1 - 2.2e-53 179.9 0.0 2.6e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII88852.1 - 2e-16 60.5 0.0 2.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII88852.1 - 2.2e-06 27.0 0.0 6.3e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII88852.1 - 0.0031 16.6 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PIG-X PF08320.7 KII88853.1 - 1.6e-29 102.6 0.0 2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 6PF2K PF01591.13 KII88854.1 - 5e-71 238.3 0.0 6.8e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KII88854.1 - 3.1e-31 108.6 0.0 5.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KII88854.1 - 5.1e-08 32.8 0.1 9.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII88854.1 - 0.00022 22.0 0.1 0.0016 19.2 0.0 2.2 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KII88854.1 - 0.016 14.3 0.1 0.025 13.6 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Methyltransf_32 PF13679.1 KII88854.1 - 0.02 14.5 0.1 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain KTI12 PF08433.5 KII88854.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 GBP PF02263.14 KII88854.1 - 0.11 11.5 0.1 0.24 10.4 0.0 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Glyco_transf_8 PF01501.15 KII88855.1 - 0.0016 17.7 0.1 0.0088 15.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KII88855.1 - 0.055 13.2 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase PNK3P PF08645.6 KII88856.1 - 6.6e-46 155.6 0.0 7e-45 152.3 0.0 2.1 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KII88856.1 - 1.1e-24 86.8 0.1 8.1e-24 84.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII88856.1 - 5.7e-09 35.3 0.0 0.00046 19.3 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin Hydrolase_6 PF13344.1 KII88856.1 - 2.3e-05 24.2 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase LNS2 PF08235.8 KII88856.1 - 7.7e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) KTI12 PF08433.5 KII88856.1 - 9.4e-05 21.7 4.4 0.0088 15.2 3.0 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 KII88856.1 - 0.00075 19.4 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase HAD_2 PF13419.1 KII88856.1 - 0.0039 17.4 0.1 0.077 13.2 0.0 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 KII88856.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KII88856.1 - 0.11 13.2 0.0 0.65 10.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain PITH PF06201.8 KII88857.1 - 8.5e-42 142.4 0.1 9.7e-42 142.3 0.1 1.0 1 0 0 1 1 1 1 PITH domain Sel1 PF08238.7 KII88858.1 - 1.7e-45 152.4 26.1 2e-08 34.6 0.0 7.9 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 KII88858.1 - 0.048 14.1 0.6 3.1 8.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII88858.1 - 0.09 13.4 19.1 0.099 13.3 0.7 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat JmjC PF02373.17 KII88859.1 - 1.4e-08 34.9 2.2 2.5e-07 30.9 1.5 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 KII88859.1 - 1.3e-07 31.2 8.8 2.3e-07 30.3 6.1 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 KII88859.1 - 1.3e-05 24.7 3.4 2.1e-05 24.1 0.7 2.3 2 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.1 KII88859.1 - 0.021 14.1 4.1 0.042 13.1 2.9 1.5 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_5 PF13719.1 KII88859.1 - 0.14 11.7 1.9 0.38 10.3 1.3 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF1423 PF07227.6 KII88859.1 - 0.27 9.8 4.6 1.5 7.3 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) DUF4206 PF13901.1 KII88859.1 - 0.35 10.4 5.1 0.64 9.5 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) zinc_ribbon_4 PF13717.1 KII88859.1 - 0.37 10.5 2.4 1 9.0 1.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Prok-RING_1 PF14446.1 KII88859.1 - 4.8 7.0 8.7 0.76 9.5 3.0 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PGK PF00162.14 KII88860.1 - 1.5e-148 494.4 0.0 1.7e-148 494.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase CAF-1_p150 PF11600.3 KII88861.1 - 0.12 11.7 19.5 0.21 10.9 13.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atg14 PF10186.4 KII88861.1 - 0.5 9.2 11.3 0.67 8.8 7.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KII88861.1 - 4.3 6.8 7.6 5.5 6.5 5.3 1.1 1 0 0 1 1 1 0 IncA protein SDA1 PF05285.7 KII88862.1 - 4.6e-78 262.7 39.1 9.8e-78 261.6 21.9 2.6 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KII88862.1 - 8.7e-23 80.3 0.0 3e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 NUC130/3NT domain CFEM PF05730.6 KII88863.1 - 4.2e-10 39.3 15.4 7.2e-10 38.5 10.7 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 KII88863.1 - 4 7.5 7.9 0.13 12.2 0.8 1.9 3 0 0 3 3 3 0 Gamma-thionin family Tmemb_cc2 PF10267.4 KII88863.1 - 5.1 5.5 5.8 5.3 5.5 4.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DEAD PF00270.24 KII88864.1 - 1.5e-41 141.6 0.0 1.4e-40 138.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII88864.1 - 1.4e-22 79.2 0.0 5.2e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII88864.1 - 5e-05 23.2 0.2 0.0098 15.7 0.0 2.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KII88864.1 - 0.0015 18.5 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KII88864.1 - 0.0038 15.6 0.1 0.07 11.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) SNF2_N PF00176.18 KII88864.1 - 0.034 12.9 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain SecA_DEAD PF07517.9 KII88864.1 - 0.077 12.2 0.0 0.18 11.0 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain CMS1 PF14617.1 KII88864.1 - 0.089 11.8 6.2 0.64 9.0 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ycf1 PF05758.7 KII88864.1 - 1.1 6.9 3.9 1.5 6.4 2.7 1.1 1 0 0 1 1 1 0 Ycf1 DEAD PF00270.24 KII88866.1 - 4.8e-25 87.9 0.0 1e-22 80.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KII88866.1 - 7.4e-21 73.8 0.0 1.2e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 KII88866.1 - 2.2e-12 46.6 0.0 1.5e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 KII88866.1 - 0.00045 20.0 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peripla_BP_4 PF13407.1 KII88866.1 - 0.16 11.3 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain Nuf2 PF03800.9 KII88867.1 - 7.9e-27 94.0 0.2 3.2e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 Nuf2 family Syntaxin_2 PF14523.1 KII88867.1 - 0.001 19.0 8.5 0.001 19.0 5.9 3.4 2 1 1 4 4 4 1 Syntaxin-like protein GAS PF13851.1 KII88867.1 - 0.0091 15.2 39.9 0.2 10.7 10.1 3.4 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding 60KD_IMP PF02096.15 KII88867.1 - 0.91 9.1 7.9 20 4.7 0.0 3.2 2 1 1 3 3 3 0 60Kd inner membrane protein Atg14 PF10186.4 KII88867.1 - 1 8.2 36.6 1.1 8.1 5.9 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 KII88867.1 - 4.3 6.1 27.6 0.088 11.7 2.3 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 KII88867.1 - 7.8 6.8 29.8 5.2 7.4 1.8 4.5 1 1 3 5 5 5 0 Protein of unknown function (DUF972) ING PF12998.2 KII88868.1 - 1e-11 44.9 0.4 1.6e-10 41.1 0.3 2.3 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KII88868.1 - 6.2e-09 35.4 9.6 1.1e-08 34.6 6.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KII88868.1 - 0.05 13.7 1.0 0.11 12.6 0.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Pkinase_Tyr PF07714.12 KII88869.1 - 6.7e-34 117.1 0.0 2.2e-33 115.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII88869.1 - 1.2e-31 109.7 0.1 6.4e-31 107.4 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KII88869.1 - 0.0042 16.1 0.2 0.017 14.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.13 KII88870.1 - 0.0034 17.2 18.2 0.0049 16.7 12.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KII88871.1 - 1.4e-51 175.1 0.0 4.9e-51 173.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88871.1 - 1.1e-15 57.4 0.2 1.7e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KII88871.1 - 0.0038 16.9 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII88871.1 - 0.045 13.1 0.1 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 RIO1 family AAA PF00004.24 KII88872.1 - 3.3e-41 140.5 0.0 9.3e-41 139.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 KII88872.1 - 4.6e-38 130.3 0.0 7.3e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KII88872.1 - 3e-12 46.2 0.0 4.1e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 KII88872.1 - 2.5e-05 24.4 0.0 0.0013 18.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KII88872.1 - 5.2e-05 22.9 0.0 0.00018 21.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KII88872.1 - 0.00017 21.6 0.0 0.00082 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KII88872.1 - 0.00083 19.3 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KII88872.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KII88872.1 - 0.0043 17.8 0.1 0.014 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII88872.1 - 0.0063 16.2 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KII88872.1 - 0.0094 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KII88872.1 - 0.021 13.9 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KII88872.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII88872.1 - 0.031 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KII88872.1 - 0.038 14.0 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KII88872.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain HATPase_c_3 PF13589.1 KII88872.1 - 0.047 13.3 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_3 PF07726.6 KII88872.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KII88872.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KII88872.1 - 0.083 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 KII88872.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 KII88872.1 - 0.11 12.1 0.0 13 5.4 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 KII88872.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KII88872.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KII88872.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KII88873.1 - 2.4e-112 373.6 0.0 3.4e-112 373.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KII88873.1 - 1.6e-21 76.8 1.2 3.4e-21 75.8 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KII88873.1 - 2.1e-14 53.4 3.8 5.7e-14 52.0 2.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain E2R135 PF11570.3 KII88873.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Fasciclin PF02469.17 KII88874.1 - 8.2e-35 119.6 0.2 2.9e-13 49.9 0.0 4.3 3 1 0 3 3 3 3 Fasciclin domain IPPT PF01715.12 KII88875.1 - 7.4e-51 172.6 0.1 5.5e-31 107.4 0.0 2.4 2 1 0 2 2 2 2 IPP transferase AAA_18 PF13238.1 KII88875.1 - 7.2e-06 26.3 0.1 0.0015 18.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KII88875.1 - 5.9e-05 23.8 0.0 0.00017 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KII88875.1 - 0.0074 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.18 KII88875.1 - 0.029 13.7 0.4 0.059 12.7 0.3 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KII88875.1 - 0.03 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KII88875.1 - 0.03 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IPT PF01745.11 KII88875.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_16 PF13191.1 KII88875.1 - 0.066 13.2 0.2 0.34 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KII88875.1 - 0.081 13.0 0.1 0.44 10.6 0.1 2.2 1 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KII88875.1 - 0.13 11.6 0.1 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Ribosomal_L18e PF00828.14 KII88876.1 - 2.1e-18 66.9 0.0 3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PRP38 PF03371.10 KII88877.1 - 2.3e-66 222.6 0.8 2.8e-66 222.4 0.6 1.1 1 0 0 1 1 1 1 PRP38 family DUF2201_N PF13203.1 KII88877.1 - 0.028 13.5 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1777 PF08648.7 KII88877.1 - 8.6 6.0 26.1 13 5.4 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PHD PF00628.24 KII88879.1 - 4e-16 58.4 16.0 5.4e-10 38.7 3.7 2.8 3 0 0 3 3 3 2 PHD-finger zf-RING-like PF08746.6 KII88879.1 - 0.0037 17.2 7.8 0.53 10.3 2.0 2.5 2 0 0 2 2 2 2 RING-like domain zf-PHD-like PF15446.1 KII88879.1 - 0.0072 15.6 4.2 0.018 14.3 0.2 2.5 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KII88879.1 - 0.014 15.1 4.9 0.62 9.8 0.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 KII88879.1 - 0.2 11.8 5.1 0.049 13.7 0.9 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KII88879.1 - 0.47 9.8 17.7 0.1 11.9 0.4 3.4 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.1 KII88879.1 - 3.6 7.4 19.9 0.55 9.9 0.5 3.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 PGM_PMM_I PF02878.11 KII88880.1 - 4.4e-38 129.8 0.0 9e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KII88880.1 - 2.9e-19 69.3 0.0 7.2e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KII88880.1 - 5.2e-19 68.3 0.2 2.7e-17 62.8 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KII88880.1 - 0.00019 21.3 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 KII88880.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 MCM_bind PF09739.4 KII88881.1 - 1.1e-18 66.9 0.0 2.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 KII88881.1 - 9.1e-17 61.1 0.0 1.7e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Putative alanine racemase F-box-like PF12937.2 KII88882.1 - 1.6e-08 34.1 0.0 3.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like zf-CCHC_6 PF15288.1 KII88883.1 - 0.19 11.4 0.3 0.19 11.4 0.2 2.8 3 0 0 3 3 3 0 Zinc knuckle ArfGap PF01412.13 KII88883.1 - 2.9 7.7 11.4 0.31 10.8 2.9 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf RNase_H PF00075.19 KII88887.1 - 0.00024 21.4 0.4 0.0012 19.1 0.1 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 KII88888.1 - 0.001 19.3 0.7 0.0014 18.8 0.2 1.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF484 PF04340.7 KII88889.1 - 0.00031 20.2 0.3 0.00051 19.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF484 CAF-1_p150 PF11600.3 KII88889.1 - 0.013 14.9 8.2 0.1 11.9 0.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal F-box PF00646.28 KII88889.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.4 2 0 0 2 2 2 0 F-box domain R3H PF01424.17 KII88890.1 - 4.1e-12 45.6 0.1 7.9e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 KII88890.1 - 8.9e-08 31.6 0.0 2.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII88890.1 - 2e-07 30.9 0.0 9.9e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII88890.1 - 0.00061 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 KII88892.1 - 4.8e-45 152.4 0.0 5.8e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KII88892.1 - 0.00092 19.0 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain EF-hand_4 PF12763.2 KII88893.1 - 9.3e-36 121.7 0.0 3.7e-14 52.3 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KII88893.1 - 7.7e-08 32.3 0.0 0.0036 17.4 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair UBA PF00627.26 KII88893.1 - 1.1e-05 25.0 0.0 2.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 KII88893.1 - 0.00034 19.6 3.0 1.3 8.4 0.0 5.2 6 0 0 6 6 6 1 EF hand Fez1 PF06818.10 KII88893.1 - 0.0004 20.4 28.0 0.013 15.5 8.6 2.4 1 1 1 2 2 2 2 Fez1 EF-hand_8 PF13833.1 KII88893.1 - 0.011 15.3 0.3 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair WEMBL PF05701.6 KII88893.1 - 0.012 14.1 33.1 0.023 13.1 22.9 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light EF-hand_6 PF13405.1 KII88893.1 - 0.054 13.3 1.7 93 3.3 0.1 4.4 5 0 0 5 5 5 0 EF-hand domain CENP-F_leu_zip PF10473.4 KII88893.1 - 0.21 11.4 31.1 1.7 8.5 7.1 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.1 KII88893.1 - 0.25 8.9 34.2 0.56 7.8 23.7 1.5 1 1 0 1 1 1 0 AAA domain CENP-Q PF13094.1 KII88893.1 - 0.49 10.4 33.5 0.096 12.7 11.7 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 KII88893.1 - 0.62 9.8 23.9 2 8.1 16.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MUG2_C PF08593.5 KII88893.1 - 1 9.6 0.0 1 9.6 0.0 3.3 4 0 0 4 4 3 0 Meiotically up-regulated glycoproteins C-terminal Spc7 PF08317.6 KII88893.1 - 3.6 6.1 27.8 0.65 8.5 6.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 KII88893.1 - 8 6.3 26.1 2.4 8.0 6.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PDEase_II PF02112.10 KII88896.1 - 2.1e-46 158.4 0.0 4.4e-46 157.3 0.0 1.6 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KII88896.1 - 3.7e-11 42.9 0.1 5.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KII88896.1 - 0.047 13.3 0.6 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily WD40 PF00400.27 KII88898.1 - 1.9e-49 163.8 4.3 1.7e-11 43.5 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KII88898.1 - 0.00031 19.6 0.4 0.25 10.0 0.0 3.5 2 2 0 3 3 3 2 Nup133 N terminal like Striatin PF08232.7 KII88899.1 - 6.2e-35 120.4 17.2 1.1e-34 119.6 1.3 2.1 2 0 0 2 2 2 1 Striatin family PAT1 PF09770.4 KII88899.1 - 0.004 15.4 33.2 0.0037 15.5 23.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 KII88899.1 - 0.08 12.4 4.9 0.084 12.3 3.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 KII88899.1 - 0.1 12.3 4.4 0.13 12.0 3.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF4337 PF14235.1 KII88899.1 - 0.17 11.7 9.2 5.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Ax_dynein_light PF10211.4 KII88899.1 - 0.31 10.8 13.5 1.1 9.0 5.2 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4175 PF13779.1 KII88899.1 - 0.46 8.1 28.4 0.51 7.9 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Exonuc_VII_L PF02601.10 KII88899.1 - 0.54 9.4 7.5 0.65 9.1 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Serinc PF03348.10 KII88899.1 - 0.55 8.8 3.2 0.57 8.8 2.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3373 PF11853.3 KII88899.1 - 1 7.8 4.2 0.98 7.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TFIIA PF03153.8 KII88899.1 - 1.7 8.4 22.6 2 8.1 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4140 PF13600.1 KII88899.1 - 2.2 8.7 14.2 2.9 8.3 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Borrelia_P83 PF05262.6 KII88899.1 - 2.4 6.3 12.2 2.8 6.1 8.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ndc1_Nup PF09531.5 KII88899.1 - 2.7 6.2 7.1 2.5 6.4 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.9 KII88899.1 - 4.9 6.8 14.9 7 6.2 10.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF572 PF04502.8 KII88899.1 - 5.6 6.0 13.5 2.4 7.3 6.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) Med15 PF09606.5 KII88899.1 - 7.7 4.5 49.6 9.8 4.2 34.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3464 PF11947.3 KII88899.1 - 8.5 5.8 7.3 14 5.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) TMA7 PF09072.5 KII88900.1 - 3.8e-21 75.3 25.0 4.1e-21 75.1 17.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 PKK PF12474.3 KII88900.1 - 0.13 12.0 5.7 0.13 11.9 3.9 1.0 1 0 0 1 1 1 0 Polo kinase kinase DUF2098 PF09871.4 KII88900.1 - 0.42 10.5 3.9 0.46 10.4 2.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Abhydrolase_5 PF12695.2 KII88901.1 - 2.1e-11 43.7 0.1 5e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII88901.1 - 1.2e-07 31.8 5.8 3.6e-07 30.3 4.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII88901.1 - 1.4e-07 31.0 0.0 3.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KII88901.1 - 0.0021 17.6 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tannase PF07519.6 KII88901.1 - 0.003 16.3 0.1 0.0046 15.7 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.15 KII88901.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 KII88901.1 - 0.24 10.7 0.1 0.4 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Not1 PF04054.10 KII88902.1 - 1.6e-116 389.2 0.1 3.7e-116 388.1 0.1 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KII88902.1 - 2.8e-52 176.2 1.5 8.4e-52 174.7 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF4418 PF14387.1 KII88902.1 - 0.15 11.7 0.2 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Sugar_tr PF00083.19 KII88903.1 - 8.6e-75 252.0 10.5 1e-74 251.7 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII88903.1 - 6.4e-23 81.0 25.0 6.4e-23 81.0 17.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KII88903.1 - 0.00036 19.0 2.0 0.00036 19.0 1.4 3.7 2 2 1 3 3 3 3 MFS/sugar transport protein Alpha-amylase PF00128.19 KII88904.1 - 3.6e-62 210.5 0.2 5.5e-62 209.9 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KII88904.1 - 4.8e-17 61.8 0.3 1.8e-16 59.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.11 KII88904.1 - 0.031 12.0 0.1 0.16 9.6 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 HOOK PF05622.7 KII88905.1 - 7e-61 205.9 68.7 5.7e-59 199.6 17.0 3.2 1 1 2 3 3 3 3 HOOK protein NYD-SP28_assoc PF14775.1 KII88905.1 - 0.0007 19.2 1.6 0.0007 19.2 1.1 5.5 5 0 0 5 5 5 1 Sperm tail C-terminal domain ERM PF00769.14 KII88905.1 - 0.0015 18.1 21.0 0.0015 18.1 14.6 4.7 1 1 2 4 4 4 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 KII88905.1 - 0.0081 15.9 11.7 0.0081 15.9 8.1 7.3 5 1 2 7 7 7 4 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 KII88905.1 - 0.0096 15.8 2.5 0.0096 15.8 1.7 8.7 10 1 1 11 11 11 1 bZIP transcription factor Reo_sigmaC PF04582.7 KII88905.1 - 0.13 11.4 20.8 1.4 7.9 0.6 4.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Tetraspannin PF00335.15 KII88906.1 - 0.45 9.7 4.8 0.6 9.3 3.3 1.3 1 0 0 1 1 1 0 Tetraspanin family Tetraspannin PF00335.15 KII88907.1 - 0.012 14.8 12.4 0.01 15.1 7.3 1.7 1 1 1 2 2 2 0 Tetraspanin family NKAIN PF05640.9 KII88907.1 - 0.17 10.8 4.0 0.076 11.9 0.7 1.8 1 1 1 2 2 2 0 Na,K-Atpase Interacting protein DUF2592 PF10766.4 KII88907.1 - 2.9 7.2 7.7 0.24 10.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) RTC PF01137.16 KII88908.1 - 1.1e-70 236.9 0.0 1.3e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KII88908.1 - 5.3e-21 74.5 1.7 7.6e-21 74.0 0.8 1.6 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CDC50 PF03381.10 KII88909.1 - 5.4e-95 317.7 0.1 8.4e-95 317.0 0.1 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family NAD_binding_7 PF13241.1 KII88910.1 - 2e-30 105.0 0.1 7.4e-30 103.2 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KII88910.1 - 3.2e-17 61.5 0.1 5.3e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KII88910.1 - 8.1e-16 56.6 1.5 1.5e-15 55.8 1.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 KII88910.1 - 0.073 12.8 1.2 0.2 11.4 0.1 2.0 1 1 1 2 2 2 0 ThiF family Endonuclease_NS PF01223.18 KII88911.1 - 8e-53 179.1 0.0 9.5e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MRP-L46 PF11788.3 KII88912.1 - 8.1e-18 65.1 1.7 1.4e-17 64.3 1.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KII88912.1 - 2.2e-05 24.1 0.7 3.8e-05 23.3 0.0 1.7 2 1 0 2 2 2 1 NUDIX domain Herpes_LMP2 PF07415.6 KII88912.1 - 0.1 11.1 0.2 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF3774 PF12609.3 KII88912.1 - 2.5 8.9 6.1 0.38 11.6 1.0 2.0 2 0 0 2 2 2 0 Wound-induced protein V-ATPase_H_N PF03224.9 KII88913.1 - 3.1e-84 282.7 0.0 7.2e-84 281.5 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KII88913.1 - 2.4e-45 153.2 0.8 9.2e-45 151.4 0.2 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 KII88913.1 - 0.0014 18.9 0.2 0.18 12.1 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats Arm_2 PF04826.8 KII88913.1 - 0.0037 16.4 0.3 0.0096 15.0 0.0 1.8 2 0 0 2 2 2 1 Armadillo-like Cnd1 PF12717.2 KII88913.1 - 0.049 13.4 0.1 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KII88913.1 - 0.12 12.4 2.6 0.74 10.0 0.0 3.6 5 0 0 5 5 5 0 HEAT repeat DUF974 PF06159.8 KII88914.1 - 1.6e-60 204.6 0.0 2.1e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) 60KD_IMP PF02096.15 KII88915.1 - 3.5e-19 69.2 9.0 4.6e-19 68.8 6.3 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein FAD-oxidase_C PF02913.14 KII88916.1 - 3e-51 174.1 0.1 6.9e-51 172.9 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KII88916.1 - 4.7e-31 107.1 0.0 9.7e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HlyC PF02794.11 KII88916.1 - 0.085 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RTX toxin acyltransferase family DUF3321 PF11968.3 KII88917.1 - 1.2e-63 214.7 0.0 1.6e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KII88917.1 - 3.6e-05 23.5 0.0 6.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MBF1 PF08523.5 KII88918.1 - 5.9e-24 83.8 3.3 1.2e-23 82.8 2.3 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KII88918.1 - 4.9e-11 42.3 0.1 7.9e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KII88918.1 - 6.4e-05 22.9 0.1 9.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KII88918.1 - 0.0078 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Tubulin PF00091.20 KII88919.1 - 4.9e-72 242.2 0.0 9e-72 241.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KII88919.1 - 2.8e-47 159.8 0.1 5.9e-47 158.8 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KII88919.1 - 0.0003 20.8 0.0 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Ribosomal_L34 PF00468.12 KII88920.1 - 0.021 14.5 0.5 0.05 13.2 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L34 RNA12 PF10443.4 KII88921.1 - 1.1e-117 393.1 0.0 3.7e-117 391.4 0.0 1.7 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 KII88921.1 - 6.5e-07 29.5 0.3 4.3e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KII88921.1 - 4.1e-05 23.3 0.0 0.00037 20.2 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KII88921.1 - 0.0024 18.0 0.1 0.0081 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain RRM_1 PF00076.17 KII88921.1 - 0.0068 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_33 PF13671.1 KII88921.1 - 0.0069 16.2 0.5 0.39 10.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII88921.1 - 0.016 14.2 0.0 0.047 12.7 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 KII88921.1 - 0.027 14.2 0.0 0.21 11.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KII88921.1 - 0.069 13.4 0.2 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 KII88921.1 - 0.098 12.0 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KII88921.1 - 0.19 11.4 2.0 2.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain Tetraspannin PF00335.15 KII88922.1 - 7.7e-05 22.0 17.7 0.00017 20.9 12.3 1.4 1 1 0 1 1 1 1 Tetraspanin family CMV_US PF08001.6 KII88922.1 - 0.14 11.1 0.3 0.26 10.3 0.1 1.4 2 0 0 2 2 2 0 CMV US DUF1440 PF07274.7 KII88922.1 - 0.69 9.8 2.9 11 6.0 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) DUF4191 PF13829.1 KII88922.1 - 1.6 7.8 4.9 3.9 6.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2420 PF10336.4 KII88923.1 - 4.7e-13 48.7 0.0 8.6e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) 5_nucleotid_C PF02872.13 KII88925.1 - 1.3e-22 80.4 0.0 2.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KII88925.1 - 7.5e-09 35.2 0.3 1.9e-08 33.9 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_9 PF08221.6 KII88926.1 - 8.2e-17 60.8 0.4 5.7e-14 51.7 0.2 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 KII88926.1 - 1.8e-14 53.9 0.7 1.4e-12 47.6 1.2 2.6 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 KII88926.1 - 3.4e-11 42.5 0.0 6.4e-08 32.0 0.0 4.4 4 1 1 5 5 5 1 TFIIE alpha subunit XPA_C PF05181.7 KII88927.1 - 0.06 12.9 0.9 0.45 10.1 0.5 2.2 1 1 1 2 2 2 0 XPA protein C-terminus EB1_binding PF05937.6 KII88927.1 - 0.14 12.5 0.1 0.14 12.5 0.1 1.6 2 0 0 2 2 2 0 EB-1 Binding Domain zf-C2H2 PF00096.21 KII88928.1 - 0.5 10.8 4.2 0.16 12.3 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type TMA7 PF09072.5 KII88931.1 - 1.2e-18 67.2 14.1 1.6e-18 66.8 9.7 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 Metallophos PF00149.23 KII88933.1 - 6.9e-10 38.6 0.4 1.8e-09 37.2 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII88933.1 - 1.4e-06 28.2 0.0 4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SPT16 PF08644.6 KII88934.1 - 1.1e-55 187.6 0.3 2.8e-55 186.3 0.2 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KII88934.1 - 4.4e-43 146.6 0.0 1.5e-42 144.8 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KII88934.1 - 2.5e-23 82.7 0.0 4.4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KII88934.1 - 1.7e-20 72.8 0.0 4.2e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 KII88934.1 - 0.091 12.3 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) DUF3772 PF12607.3 KII88935.1 - 0.081 12.5 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) TF_Zn_Ribbon PF08271.7 KII88936.1 - 0.0011 18.2 0.4 0.0021 17.3 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Abhydrolase_6 PF12697.2 KII88937.1 - 4e-30 105.3 0.3 5.3e-30 104.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII88937.1 - 1.4e-18 67.2 0.0 6.9e-17 61.7 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII88937.1 - 6.1e-15 55.2 0.0 9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KII88937.1 - 5.4e-07 29.3 0.3 4.6e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KII88937.1 - 0.00046 20.0 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 KII88937.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KII88937.1 - 0.014 14.5 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 KII88937.1 - 0.043 13.0 0.1 0.64 9.2 0.1 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.8 KII88937.1 - 0.094 12.1 0.0 0.41 10.0 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase (FSH1) UPF0227 PF05728.7 KII88937.1 - 0.1 12.2 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 KII88937.1 - 0.11 11.3 0.1 0.6 8.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) BAAT_C PF08840.6 KII88937.1 - 0.13 11.9 0.1 2.6 7.7 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DEAD PF00270.24 KII88939.1 - 2.6e-19 69.3 0.0 4.3e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII88939.1 - 4.1e-14 52.1 0.4 1.3e-10 40.9 0.0 3.5 3 1 0 3 3 3 2 Helicase conserved C-terminal domain DUF1998 PF09369.5 KII88939.1 - 1.8e-10 41.2 0.5 5.6e-10 39.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 KII88939.1 - 1.8e-07 31.2 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like Pkinase PF00069.20 KII88940.1 - 4.6e-22 78.4 0.0 6.9e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII88940.1 - 8.1e-12 44.7 0.0 1.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase NYN PF01936.13 KII88941.1 - 6.5e-23 81.6 0.0 8.9e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 NYN domain OGFr_III PF04680.8 KII88945.1 - 0.036 14.1 1.1 0.093 12.8 0.8 1.7 1 0 0 1 1 1 0 Opioid growth factor receptor repeat Arrestin_C PF02752.17 KII88947.1 - 0.0011 19.0 0.0 0.12 12.4 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain NAD_binding_2 PF03446.10 KII88948.1 - 3.2e-38 131.1 0.0 4.6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KII88948.1 - 1.2e-32 112.5 0.0 1.3e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KII88948.1 - 0.00015 22.1 0.0 0.00043 20.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KII88949.1 - 0.023 14.1 0.0 0.056 12.8 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DNA_pol_E_B PF04042.11 KII88950.1 - 3.8e-34 117.7 0.3 2.4e-33 115.1 0.2 2.0 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NYN PF01936.13 KII88951.1 - 1.2e-24 87.2 0.0 2.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 NYN domain MR_MLE_C PF13378.1 KII88951.1 - 0.0077 16.1 0.5 16 5.5 0.0 3.7 4 0 0 4 4 4 1 Enolase C-terminal domain-like HTH_33 PF13592.1 KII88951.1 - 0.15 11.5 0.2 0.36 10.3 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix NYN PF01936.13 KII88952.1 - 2.9e-23 82.7 0.0 1.5e-22 80.4 0.0 2.2 3 0 0 3 3 3 1 NYN domain CHCH PF06747.8 KII88953.1 - 5.5e-05 22.9 0.1 9.6e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KII88953.1 - 0.012 15.4 1.6 0.02 14.6 1.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 KII88953.1 - 0.083 13.0 0.2 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) UQ_con PF00179.21 KII88954.1 - 1.8e-21 76.0 0.0 2.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KII88954.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF4658 PF15555.1 KII88954.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) zf-RanBP PF00641.13 KII88954.1 - 2.1 7.5 4.7 0.49 9.5 0.5 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP21_like_P PF12230.3 KII88956.1 - 8.5e-55 185.7 15.1 8.5e-55 185.7 10.5 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KII88956.1 - 5.3e-34 115.6 0.5 4e-16 58.3 0.1 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 KII88956.1 - 0.00057 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KII88956.1 - 0.0057 16.3 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like L31 PF09784.4 KII88957.1 - 1.6e-38 130.9 0.1 1.8e-38 130.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.1 KII88958.1 - 6.6e-76 254.7 0.6 7.8e-76 254.4 0.4 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AOX PF01786.12 KII88958.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.7 1 1 1 2 2 2 0 Alternative oxidase RNase_T PF00929.19 KII88959.1 - 1.7e-12 47.9 0.0 1.3e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 Exonuclease Herpes_IE68 PF02479.11 KII88959.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus immediate early protein Ndc80_HEC PF03801.8 KII88961.1 - 2.2e-30 105.2 0.0 4.3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Fib_alpha PF08702.5 KII88961.1 - 0.086 12.9 18.9 0.54 10.3 2.6 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.3 KII88961.1 - 0.2 11.3 10.4 2 8.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) KxDL PF10241.4 KII88961.1 - 0.69 9.8 9.1 0.48 10.3 1.2 3.2 1 1 0 2 2 2 0 Uncharacterized conserved protein Flagellin_N PF00669.15 KII88961.1 - 1.1 8.9 6.4 0.97 9.2 0.5 2.6 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region NPV_P10 PF05531.7 KII88961.1 - 1.7 8.9 9.5 3.7 7.8 0.2 4.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 KII88961.1 - 7 5.6 29.9 0.042 12.8 2.9 2.8 2 1 1 3 3 3 0 Autophagy protein Apg6 Mog1 PF04603.7 KII88962.1 - 2.9e-31 108.3 0.0 3.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein PaREP1 PF05942.6 KII88963.1 - 9.1e-05 22.3 0.1 9.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DUF972 PF06156.8 KII88963.1 - 0.01 16.1 11.4 0.86 9.9 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Orbi_VP5 PF00901.12 KII88963.1 - 0.011 13.9 0.5 0.011 13.9 0.4 1.6 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 Kinesin-relat_1 PF12711.2 KII88963.1 - 0.08 13.3 0.3 0.08 13.3 0.2 2.5 3 0 0 3 3 2 0 Kinesin motor Striatin PF08232.7 KII88963.1 - 0.87 9.9 11.0 2 8.7 2.7 3.1 3 0 0 3 3 3 0 Striatin family DUF2383 PF09537.5 KII88963.1 - 0.99 9.6 10.8 0.8 9.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) DUF3186 PF11382.3 KII88963.1 - 1.5 7.8 6.0 13 4.8 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3186) Sox_N PF12444.3 KII88963.1 - 2.5 9.2 0.0 2.5 9.2 0.0 3.5 4 0 0 4 4 4 0 Sox developmental protein N terminal DUF3450 PF11932.3 KII88963.1 - 2.7 7.2 11.8 0.029 13.6 1.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DivIVA PF05103.8 KII88963.1 - 4.5 7.3 20.6 1.1 9.3 1.5 2.9 3 0 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 KII88963.1 - 6 7.2 15.3 6.6 7.1 0.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF904) WD40_alt PF14077.1 KII88963.1 - 6.4 6.4 6.8 0.64 9.6 1.4 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif HECT PF00632.20 KII88965.1 - 6.9e-89 298.1 0.0 9.4e-89 297.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KII88965.1 - 1.3e-33 114.4 21.3 1.5e-11 43.9 4.1 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KII88965.1 - 1.5e-15 56.8 0.1 3.4e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain Pox_MCEL PF03291.11 KII88966.1 - 5.8e-83 278.5 0.0 5.3e-72 242.4 0.0 2.0 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_23 PF13489.1 KII88966.1 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII88966.1 - 1.2e-09 38.5 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII88966.1 - 3.3e-09 37.1 0.0 7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII88966.1 - 1.3e-08 35.3 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII88966.1 - 1.5e-08 34.4 0.0 2.3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII88966.1 - 7.2e-07 29.5 0.1 2.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII88966.1 - 0.00015 21.7 0.1 0.0005 20.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KII88966.1 - 0.00083 18.3 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family TPMT PF05724.6 KII88966.1 - 0.0089 15.4 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 KII88966.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M1 PF01433.15 KII88967.1 - 4.5e-111 371.6 0.0 1.9e-72 244.5 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 KII88967.1 - 1.4e-57 195.4 0.2 2.3e-57 194.7 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KII88967.1 - 5e-16 58.9 1.2 1.3e-15 57.5 0.0 2.3 3 0 0 3 3 3 1 Peptidase MA superfamily TEA PF01285.13 KII88969.1 - 8e-26 91.1 0.0 1.2e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 TEA/ATTS domain family Lipase_GDSL_2 PF13472.1 KII88970.1 - 5.9e-28 98.2 0.2 7.7e-28 97.8 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII88970.1 - 1.5e-21 77.3 0.0 2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Telomere_reg-2 PF10193.4 KII88971.1 - 8.5e-26 90.4 0.0 1.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein 2Fe-2S_thioredx PF01257.14 KII88972.1 - 2.1e-59 199.2 0.0 2.6e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF3786 PF12654.2 KII88972.1 - 0.042 13.1 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Bestrophin PF01062.16 KII88973.1 - 2.3e-44 151.5 0.9 3.5e-27 95.1 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel PsbH PF00737.15 KII88973.1 - 2.3 7.8 5.0 8.2 6.0 0.5 2.4 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Rhodanese PF00581.15 KII88974.1 - 2e-13 50.6 0.0 4.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Fer4_3 PF12798.2 KII88975.1 - 0.83 10.3 5.5 1.4 9.6 0.4 3.0 3 1 0 3 3 3 0 4Fe-4S binding domain adh_short PF00106.20 KII88976.1 - 3e-19 69.5 0.0 5.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII88976.1 - 3.5e-09 36.5 0.0 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII88976.1 - 3.9e-09 36.6 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII88976.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII88976.1 - 0.0089 16.0 0.1 0.023 14.7 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 KII88976.1 - 0.014 14.8 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Glyco_hydro_15 PF00723.16 KII88977.1 - 2.4e-91 306.5 0.0 2.8e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KII88977.1 - 2.3e-24 84.8 0.4 5.3e-24 83.6 0.3 1.7 1 0 0 1 1 1 1 Starch binding domain Cpn60_TCP1 PF00118.19 KII88978.1 - 2.3e-140 468.4 10.3 2.6e-140 468.3 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 KII88978.1 - 0.0063 15.7 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination TPR_11 PF13414.1 KII88979.1 - 7.4e-24 83.1 19.7 1.4e-06 27.8 0.0 8.4 6 2 2 9 9 9 5 TPR repeat TPR_2 PF07719.12 KII88979.1 - 1.5e-21 74.4 14.5 7e-05 22.4 0.1 10.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 KII88979.1 - 2.6e-19 67.9 5.6 1.5e-07 30.7 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII88979.1 - 3.7e-17 61.0 4.1 0.012 15.7 0.0 7.2 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KII88979.1 - 7.6e-17 61.5 24.7 8.3e-06 26.3 0.1 9.5 8 2 3 11 11 10 2 Tetratricopeptide repeat Apc3 PF12895.2 KII88979.1 - 3e-15 56.1 10.6 3.7e-11 43.0 0.4 5.5 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KII88979.1 - 1.3e-14 53.9 6.6 5.9e-06 26.1 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII88979.1 - 9.5e-13 47.5 12.1 0.14 12.8 0.0 10.1 4 1 7 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII88979.1 - 2e-12 45.9 0.0 0.0014 18.2 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII88979.1 - 7.2e-12 45.4 1.9 1 9.7 0.0 7.4 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KII88979.1 - 1e-09 38.2 0.5 1.5 9.4 0.0 7.5 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KII88979.1 - 5.4e-06 26.1 1.9 0.013 15.3 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII88979.1 - 3.6e-05 23.2 1.0 32 4.6 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KII88979.1 - 0.26 11.4 3.6 17 5.6 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Aldolase_II PF00596.16 KII88980.1 - 4.6e-46 156.7 0.1 5.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain G-patch PF01585.18 KII88981.1 - 5.1e-07 29.3 1.3 1.4e-06 27.9 0.9 1.8 1 0 0 1 1 1 1 G-patch domain FAD_binding_2 PF00890.19 KII88982.1 - 5.7e-127 424.0 1.9 7.1e-127 423.7 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KII88982.1 - 5.7e-45 152.3 0.2 8.2e-45 151.8 0.1 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KII88982.1 - 2.5e-07 30.7 0.0 0.00069 19.5 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII88982.1 - 8.6e-07 28.2 0.1 0.0032 16.6 0.0 3.2 4 0 0 4 4 4 2 Thi4 family DAO PF01266.19 KII88982.1 - 1.4e-05 24.1 0.8 0.00084 18.3 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KII88982.1 - 2.6e-05 23.2 2.3 0.0099 14.7 1.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KII88982.1 - 0.0029 16.7 0.2 0.0047 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KII88982.1 - 0.088 12.8 0.1 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII88982.1 - 0.24 9.8 2.8 0.5 8.7 0.4 2.5 4 0 0 4 4 4 0 HI0933-like protein RabGAP-TBC PF00566.13 KII88983.1 - 4.5e-30 104.7 0.1 6.8e-29 100.8 0.1 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Fungal_trans PF04082.13 KII88984.1 - 1.7e-17 63.1 0.7 6.9e-17 61.1 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII88984.1 - 4.1e-05 23.3 11.0 6.7e-05 22.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CsbD PF05532.7 KII88985.1 - 0.038 13.6 0.4 0.067 12.8 0.3 1.3 1 0 0 1 1 1 0 CsbD-like Oligomerisation PF02410.10 KII88987.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain SHR3_chaperone PF08229.6 KII88988.1 - 2.6e-29 101.6 0.1 4e-29 100.9 0.0 1.3 1 1 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 KII88988.1 - 0.039 14.3 0.1 0.27 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ApbA_C PF08546.6 KII88988.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal LETM1 PF07766.8 KII88989.1 - 8.7e-100 333.1 0.0 8.7e-100 333.1 0.0 2.1 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 KII88989.1 - 6.5e-06 25.5 1.5 0.0012 18.3 0.0 3.5 4 0 0 4 4 4 1 SAP domain EF-hand_1 PF00036.27 KII88989.1 - 0.0042 16.2 0.0 0.089 12.1 0.0 3.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KII88989.1 - 0.0062 16.6 0.0 0.077 13.1 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KII88989.1 - 0.0069 16.1 0.0 2.5 8.2 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KII88989.1 - 0.049 12.9 0.1 0.88 9.0 0.0 2.8 2 0 0 2 2 2 0 EF hand Glycos_transf_1 PF00534.15 KII88991.1 - 1.8e-22 79.5 0.0 3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KII88991.1 - 5.5e-09 36.2 0.0 1.4e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KII88991.1 - 1.9e-06 28.0 0.0 5.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 2OG-FeII_Oxy_2 PF13532.1 KII88992.1 - 5.4e-37 127.5 0.0 6.3e-36 124.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Dmrt1 PF12374.3 KII88992.1 - 3.8 7.9 6.8 2.6 8.4 3.1 1.9 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 DNA_pol_phi PF04931.8 KII88994.1 - 8.9e-66 222.2 13.8 8.9e-66 222.2 9.5 2.7 2 1 0 2 2 2 1 DNA polymerase phi DUF2457 PF10446.4 KII88994.1 - 0.00054 18.8 15.4 0.00054 18.8 10.7 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) MutS_V PF00488.16 KII88995.1 - 3.6e-80 268.7 0.0 1.1e-79 267.1 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KII88995.1 - 8.4e-41 140.0 0.3 8.4e-41 140.0 0.2 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KII88995.1 - 2.5e-26 91.9 0.0 5.5e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KII88995.1 - 2.1e-09 37.3 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KII88995.1 - 3.6e-09 36.7 0.0 9.2e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II ATP12 PF07542.6 KII88996.1 - 1.6e-37 128.1 0.0 2.7e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF3025 PF11227.3 KII88996.1 - 0.033 13.7 0.4 0.088 12.3 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3025) PLRV_ORF5 PF01690.12 KII88996.1 - 9.2 5.2 9.5 9.8 5.1 5.5 1.8 2 1 1 3 3 3 0 Potato leaf roll virus readthrough protein adh_short PF00106.20 KII88997.1 - 1.8e-23 83.2 1.8 2.6e-23 82.7 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII88997.1 - 9.9e-14 51.3 0.3 1.3e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII88997.1 - 3.8e-07 29.7 0.0 1.2e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KII88997.1 - 0.00012 21.9 0.1 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TP_methylase PF00590.15 KII88997.1 - 0.033 13.8 0.2 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases p450 PF00067.17 KII88998.1 - 1.2e-62 212.0 0.0 1.5e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nt_Gln_amidase PF09764.4 KII89001.1 - 1.2e-33 116.0 0.0 1.8e-33 115.3 0.0 1.3 1 1 0 1 1 1 1 N-terminal glutamine amidase BTB PF00651.26 KII89002.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RCC1_2 PF13540.1 KII89003.1 - 0.05 13.2 0.6 0.098 12.3 0.4 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat MYCBPAP PF14646.1 KII89003.1 - 0.082 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family UQ_con PF00179.21 KII89005.1 - 9.8e-41 138.4 0.1 1.1e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII89005.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KII89005.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KII89005.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain SPRY PF00622.23 KII89006.1 - 7.9e-08 32.4 0.0 6.1e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 SPRY domain PhoD PF09423.5 KII89007.1 - 0.00015 20.5 0.3 0.26 9.8 0.0 2.6 3 0 0 3 3 3 2 PhoD-like phosphatase CAP_N PF01213.14 KII89008.1 - 6.9e-89 298.2 19.5 7.9e-89 298.0 12.5 2.3 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KII89008.1 - 1e-52 177.6 8.4 1.4e-52 177.2 5.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KII89008.1 - 0.0012 18.2 4.7 0.0027 17.0 3.4 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C FERM_N PF09379.5 KII89008.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain DUF2360 PF10152.4 KII89008.1 - 0.44 10.8 10.4 10 6.3 0.3 3.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) tRNA_int_endo PF01974.12 KII89009.1 - 9.5e-14 50.9 0.0 1.6e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain EI24 PF07264.6 KII89010.1 - 4.7e-32 111.2 13.5 1e-31 110.1 9.3 1.5 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF204 PF02659.10 KII89010.1 - 0.11 12.6 1.1 3.4 7.8 0.7 2.5 1 1 0 1 1 1 0 Domain of unknown function DUF Linker_histone PF00538.14 KII89011.1 - 1.6e-15 56.9 0.0 4.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family RF-1 PF00472.15 KII89012.1 - 5.9e-24 84.0 4.5 5.9e-24 84.0 3.1 1.8 2 0 0 2 2 2 1 RF-1 domain Aldo_ket_red PF00248.16 KII89013.1 - 8.3e-47 159.3 0.0 9.4e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 KII89013.1 - 0.0074 16.5 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Linker_histone PF00538.14 KII89014.1 - 6.5e-11 42.1 0.0 1.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF202 PF02656.10 KII89016.1 - 8.8 6.6 10.7 1.2 9.3 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Aldo_ket_red PF00248.16 KII89017.1 - 1.9e-46 158.1 0.0 2.1e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 KII89018.1 - 5.2e-14 51.4 0.0 9.1e-14 50.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.14 KII89019.1 - 5.2e-15 55.2 0.1 1.8e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family RRM_1 PF00076.17 KII89020.1 - 2.4e-25 87.9 0.0 2e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 KII89020.1 - 2.3e-19 67.7 0.0 0.00022 20.5 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 KII89020.1 - 4.7e-17 61.7 0.0 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII89020.1 - 6.9e-14 51.4 0.0 1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCC1 PF00415.13 KII89024.1 - 1.2e-19 70.1 10.7 3.6e-05 23.8 0.1 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII89024.1 - 2.6e-11 42.8 21.2 6.6e-06 25.5 0.2 6.6 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DUF4230 PF14014.1 KII89025.1 - 5.3 6.8 9.5 10 5.9 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) AUX_IAA PF02309.11 KII89025.1 - 5.6 6.6 8.3 10 5.8 5.8 1.4 1 0 0 1 1 1 0 AUX/IAA family DPBB_1 PF03330.13 KII89026.1 - 1.1e-05 25.3 0.0 4.5e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII89026.1 - 0.025 14.2 0.0 0.061 12.9 0.0 1.7 1 0 0 1 1 1 0 Barwin family Med3 PF11593.3 KII89026.1 - 0.77 8.9 23.7 1 8.5 16.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hex_IIIa PF02455.11 KII89026.1 - 5.8 5.4 7.6 7.6 5.0 5.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Golgin_A5 PF09787.4 KII89026.1 - 8.8 4.7 17.5 12 4.2 12.1 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DPBB_1 PF03330.13 KII89027.1 - 0.00017 21.5 0.1 0.00046 20.1 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII89027.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Barwin family MGC-24 PF05283.6 KII89027.1 - 0.017 14.9 17.6 0.025 14.3 12.2 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TIM-br_sig_trns PF09370.5 KII89027.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 TIM-barrel signal transduction protein SOG2 PF10428.4 KII89027.1 - 0.35 9.4 9.1 0.38 9.3 6.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.6 KII89027.1 - 1.7 6.6 12.6 2.1 6.3 8.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF605 PF04652.11 KII89027.1 - 2.2 7.6 14.5 2.9 7.2 10.1 1.1 1 0 0 1 1 1 0 Vta1 like SoxE PF06525.6 KII89027.1 - 5.2 6.2 13.1 8.6 5.5 9.1 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) TFIIA PF03153.8 KII89027.1 - 6.4 6.5 7.6 7.8 6.2 5.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit E1-E2_ATPase PF00122.15 KII89028.1 - 6.8e-66 221.5 6.6 2.8e-65 219.5 3.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KII89028.1 - 3e-44 150.7 9.2 3e-44 150.7 6.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KII89028.1 - 1.6e-33 116.9 0.0 8e-33 114.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII89028.1 - 7.7e-22 77.0 0.0 1.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KII89028.1 - 2.4e-21 74.9 0.6 4.6e-20 70.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KII89028.1 - 5e-14 52.9 0.1 1.3e-13 51.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KII89028.1 - 9.1e-07 28.7 2.0 6e-06 26.0 1.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KII89028.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CBP4 PF07960.6 KII89030.1 - 2.3e-11 43.4 0.0 2.9e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 KII89030.1 - 0.042 13.5 0.2 0.052 13.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4574) DUF3665 PF12427.3 KII89030.1 - 0.094 12.0 1.0 0.18 11.2 0.7 1.4 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase BRCT PF00533.21 KII89031.1 - 6.3e-05 23.0 0.0 0.046 13.8 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PNK3P PF08645.6 KII89032.1 - 2.8e-45 153.6 0.0 3.4e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.1 KII89032.1 - 0.028 14.6 0.2 0.46 10.6 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Metallophos PF00149.23 KII89033.1 - 1.3e-08 34.5 0.7 2.2e-08 33.7 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII89033.1 - 6.8e-08 32.5 0.1 9.2e-08 32.0 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aconitase_2_N PF06434.8 KII89033.1 - 0.11 11.9 0.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus SHQ1 PF04925.10 KII89034.1 - 1.1e-50 171.6 0.0 1.9e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 SHQ1 protein PIH1 PF08190.7 KII89034.1 - 0.0027 17.2 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 PDEase_II PF02112.10 KII89037.1 - 0.065 12.1 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PDEase_II PF02112.10 KII89038.1 - 3.5e-18 65.6 0.0 7e-18 64.6 0.0 1.4 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KII89038.1 - 1.1e-07 31.6 0.1 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KII89038.1 - 0.031 13.9 0.5 0.058 13.0 0.3 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Nuc_sug_transp PF04142.10 KII89039.1 - 5.3e-09 35.5 1.0 8.1e-09 34.9 0.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KII89039.1 - 7.8e-08 31.5 4.9 1.1e-07 31.0 3.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KII89039.1 - 9.2e-05 22.4 3.2 9.2e-05 22.4 2.2 3.2 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KII89039.1 - 0.001 19.2 3.3 0.001 19.2 2.3 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KII89039.1 - 0.016 14.8 15.5 0.19 11.3 0.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Arrestin_N PF00339.24 KII89040.1 - 0.005 16.6 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_C14 PF00656.17 KII89041.1 - 4.7e-72 242.6 0.0 6.1e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Chorismate_bind PF00425.13 KII89042.1 - 9.5e-89 297.1 0.0 1.4e-88 296.5 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KII89042.1 - 1.8e-29 102.5 0.0 3.5e-28 98.3 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.15 KII89043.1 - 8.5e-47 159.0 0.0 1.2e-44 152.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 HSP70 PF00012.15 KII89044.1 - 1.7e-241 802.3 5.8 1.9e-241 802.1 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KII89044.1 - 1.8e-16 59.6 0.4 1.6e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.15 KII89044.1 - 0.0016 17.7 0.1 0.55 9.4 0.0 2.5 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.5 KII89044.1 - 0.0082 15.0 0.5 0.052 12.3 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 KII89044.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 KII89044.1 - 0.037 12.9 0.0 0.088 11.7 0.0 1.6 1 0 0 1 1 1 0 StbA protein RE_CfrBI PF09516.5 KII89044.1 - 0.065 12.1 1.2 0.19 10.5 0.1 2.0 2 0 0 2 2 2 0 CfrBI restriction endonuclease Hydantoinase_A PF01968.13 KII89044.1 - 0.12 11.4 2.3 0.23 10.5 0.1 2.4 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase F-box-like PF12937.2 KII89045.1 - 0.002 17.7 0.3 0.0096 15.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 KII89045.1 - 0.65 10.4 2.9 56 4.6 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat Amino_oxidase PF01593.19 KII89046.1 - 6.6e-59 200.1 0.4 1.2e-58 199.3 0.3 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII89046.1 - 1.1e-17 63.8 0.1 2.2e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII89046.1 - 2.4e-10 39.8 5.1 5.2e-09 35.4 3.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KII89046.1 - 4.4e-07 29.2 0.1 9.2e-07 28.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KII89046.1 - 1.4e-06 27.4 1.3 1.5e-06 27.3 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KII89046.1 - 4.4e-06 25.4 2.2 6e-05 21.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KII89046.1 - 4.6e-06 26.8 0.2 1.4e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII89046.1 - 1.1e-05 24.7 0.4 2e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII89046.1 - 3.5e-05 23.0 2.0 9e-05 21.6 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KII89046.1 - 7.7e-05 23.0 0.9 0.0011 19.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII89046.1 - 0.00033 20.6 0.3 0.00059 19.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII89046.1 - 0.00095 18.1 0.6 0.056 12.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KII89046.1 - 0.003 16.4 0.1 0.0051 15.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KII89046.1 - 0.67 9.7 3.4 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAA PF00004.24 KII89047.1 - 9.1e-15 55.0 0.0 2.7e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KII89047.1 - 8.8e-13 48.2 0.0 8e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KII89047.1 - 1.4e-10 40.5 0.0 9.4e-07 27.8 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KII89047.1 - 6.1e-09 35.7 0.0 1.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 KII89047.1 - 8.2e-08 32.4 0.0 3.4e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII89047.1 - 1.2e-05 25.0 0.0 4.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KII89047.1 - 4.3e-05 23.2 0.0 6.8e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII89047.1 - 5.4e-05 22.3 0.0 0.00013 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KII89047.1 - 6.9e-05 22.9 0.0 0.00033 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KII89047.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KII89047.1 - 0.00037 20.2 0.0 0.0017 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KII89047.1 - 0.0006 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KII89047.1 - 0.0027 16.9 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KII89047.1 - 0.0028 17.2 0.0 0.0071 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KII89047.1 - 0.003 17.0 0.1 0.12 11.7 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain DUF2075 PF09848.4 KII89047.1 - 0.0037 16.2 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KII89047.1 - 0.007 17.1 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII89047.1 - 0.0082 15.5 0.0 0.019 14.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KII89047.1 - 0.013 15.0 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KII89047.1 - 0.014 15.2 0.0 0.064 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KII89047.1 - 0.018 15.0 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KII89047.1 - 0.038 12.9 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 KII89047.1 - 0.039 13.4 0.1 0.63 9.5 0.0 2.4 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_23 PF13476.1 KII89047.1 - 0.042 14.1 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KII89047.1 - 0.046 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KII89047.1 - 0.052 12.7 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 KII89047.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KII89047.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KII89047.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CAF1A PF12253.3 KII89048.1 - 2.6e-19 69.1 2.8 2.6e-19 69.1 2.0 2.5 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A LRR_1 PF00560.28 KII89049.1 - 0.011 15.6 0.5 1.2 9.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 KII89049.1 - 0.018 14.6 0.3 1.7 8.3 0.0 3.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KII89049.1 - 0.12 12.6 1.3 30 5.4 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat RNase_H PF00075.19 KII89051.1 - 3.1e-06 27.5 0.1 7.4e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.22 KII89052.1 - 0.00044 19.6 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gemini_AC4_5 PF04807.7 KII89053.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region adh_short PF00106.20 KII89055.1 - 8.3e-11 42.0 0.2 1.2e-10 41.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII89055.1 - 1.1e-05 25.1 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII89055.1 - 0.00012 21.8 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_oxidored PF12831.2 KII89055.1 - 0.038 13.0 0.3 0.047 12.7 0.2 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 KII89055.1 - 0.064 13.2 0.7 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KII89056.1 - 7.3e-09 35.7 0.5 1.1e-08 35.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII89056.1 - 4.7e-05 23.1 0.3 8e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII89056.1 - 0.0018 18.0 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_oxidored PF12831.2 KII89056.1 - 0.14 11.2 0.7 0.17 10.9 0.5 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Oxidored_FMN PF00724.15 KII89057.1 - 6.6e-72 242.3 0.0 9.9e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N_2 PF13602.1 KII89058.1 - 3.7e-22 79.5 0.0 9.2e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KII89058.1 - 2.2e-09 36.9 0.0 5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89058.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PUA PF01472.15 KII89059.1 - 1.3e-15 56.8 0.0 1.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 PUA domain CRM1_C PF08767.6 KII89060.1 - 2.5e-131 437.3 0.1 2.5e-131 437.3 0.1 3.2 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KII89060.1 - 2.8e-42 144.1 11.6 1e-41 142.3 6.7 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KII89060.1 - 3.7e-13 49.1 0.0 1.7e-12 47.0 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain ADH_zinc_N_2 PF13602.1 KII89061.1 - 2.7e-21 76.7 0.0 5.6e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KII89061.1 - 4.1e-14 52.2 0.2 1.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89061.1 - 0.0071 16.0 0.0 0.048 13.4 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Oxidored_FMN PF00724.15 KII89062.1 - 3.2e-63 213.7 0.0 6.5e-63 212.7 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.8 KII89062.1 - 0.00059 19.2 0.3 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 Repeat of unknown function (DUF346) Pkinase PF00069.20 KII89063.1 - 5.7e-52 176.4 0.0 8.3e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89063.1 - 1.2e-44 152.3 0.0 1.6e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 KII89063.1 - 0.0094 15.4 0.1 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-CHCC PF10276.4 KII89064.1 - 0.23 11.3 1.8 0.28 11.0 0.3 1.8 2 0 0 2 2 2 0 Zinc-finger domain SRR1 PF07985.7 KII89065.1 - 2.9e-17 62.3 0.0 4.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 SRR1 RNA_pol_L_2 PF13656.1 KII89066.1 - 4.8e-27 93.2 0.0 5.7e-27 92.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KII89066.1 - 1.6e-09 36.7 0.0 2.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short PF00106.20 KII89067.1 - 2.4e-08 34.0 0.2 3.3e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII89067.1 - 0.0016 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII89067.1 - 0.009 15.6 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KII89067.1 - 0.034 13.2 0.1 0.054 12.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_oxidored PF12831.2 KII89067.1 - 0.083 11.9 0.9 0.11 11.5 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase WD40 PF00400.27 KII89068.1 - 5.1e-23 80.0 1.9 9.1e-07 28.5 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KII89068.1 - 0.19 9.8 0.0 0.31 9.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 adh_short PF00106.20 KII89069.1 - 3.4e-09 36.8 1.1 5.4e-09 36.1 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII89069.1 - 1.1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII89069.1 - 8.1e-05 22.3 0.3 0.0002 21.0 0.3 1.5 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.14 KII89069.1 - 0.015 14.3 0.2 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KII89069.1 - 0.034 14.1 0.4 0.067 13.1 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 KII89069.1 - 0.089 12.2 0.6 0.21 10.9 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KII89069.1 - 0.17 11.5 1.7 0.26 10.9 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KII89069.1 - 0.18 10.8 2.3 0.25 10.3 1.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NmrA PF05368.8 KII89069.1 - 0.28 10.3 2.3 0.5 9.5 1.6 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KII89070.1 - 5.5e-10 39.4 3.5 7.9e-10 38.8 1.8 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII89070.1 - 6e-06 26.0 0.6 1.4e-05 24.8 0.3 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KII89070.1 - 0.00046 20.0 0.2 0.00085 19.1 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 KII89070.1 - 0.053 13.9 0.2 1.5 9.3 0.2 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KII89070.1 - 0.076 13.0 0.4 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KII89070.1 - 0.088 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 KII89070.1 - 0.14 11.3 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KII89070.1 - 0.16 11.0 0.8 0.25 10.3 0.5 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 KII89071.1 - 7.9e-09 35.6 0.5 1.2e-08 35.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII89071.1 - 0.00046 19.8 0.2 0.0007 19.3 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII89071.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 KII89071.1 - 0.1 11.4 0.1 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_oxidored PF12831.2 KII89071.1 - 0.15 11.0 1.8 0.21 10.6 1.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase zf-MYND PF01753.13 KII89072.1 - 2e-08 33.9 10.8 3.9e-08 33.0 7.5 1.5 1 0 0 1 1 1 1 MYND finger Spc24 PF08286.6 KII89073.1 - 2.6e-12 46.4 0.1 2.1e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 KII89073.1 - 0.061 12.4 0.2 0.072 12.2 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 KII89073.1 - 0.25 10.3 4.9 0.33 9.9 3.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 M PF02370.11 KII89073.1 - 2.9 8.5 8.0 3 8.5 0.4 2.9 2 0 0 2 2 2 0 M protein repeat Chs3p PF12271.3 KII89074.1 - 4.4e-114 380.4 22.9 5.1e-114 380.1 15.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit GATA PF00320.22 KII89075.1 - 6.1e-15 54.2 5.4 1.2e-14 53.3 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KII89075.1 - 7.9e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KII89075.1 - 0.00061 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 KII89075.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 PAS fold PAS_11 PF14598.1 KII89075.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 PAS domain DUF4428 PF14471.1 KII89075.1 - 0.23 11.2 1.3 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) adh_short_C2 PF13561.1 KII89076.1 - 4.6e-29 101.8 0.1 5.7e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII89076.1 - 7.4e-25 87.7 0.3 1.2e-24 87.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII89076.1 - 6.7e-13 48.6 0.1 3.8e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KII89076.1 - 2.2e-06 27.3 0.1 5.7e-06 25.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KII89076.1 - 0.00045 19.2 0.0 0.00074 18.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KII89076.1 - 0.051 12.2 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Kinesin PF00225.18 KII89077.1 - 2.4e-96 322.3 0.0 1.6e-55 188.1 0.0 4.3 5 0 0 5 5 5 2 Kinesin motor domain IncA PF04156.9 KII89077.1 - 0.001 18.6 12.9 0.001 18.6 8.9 13.4 4 2 6 11 11 11 4 IncA protein WD40 PF00400.27 KII89078.1 - 3.3e-81 264.5 10.4 2.5e-12 46.1 0.0 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KII89078.1 - 2.5e-09 35.8 4.7 0.03 12.4 0.0 5.3 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII89078.1 - 8.2e-06 24.8 1.9 1.4 7.5 0.0 4.4 2 2 2 4 4 4 3 Nup133 N terminal like Coatomer_WDAD PF04053.9 KII89078.1 - 0.0053 15.6 0.0 0.1 11.3 0.0 2.5 2 1 1 3 3 3 1 Coatomer WD associated region bZIP_2 PF07716.10 KII89078.1 - 0.061 13.1 0.4 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper TIM-br_sig_trns PF09370.5 KII89079.1 - 1.7e-132 440.4 0.6 2e-132 440.2 0.4 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KII89079.1 - 7.5e-05 22.0 0.3 0.00013 21.2 0.2 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase AP_endonuc_2 PF01261.19 KII89079.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Amidohydro_2 PF04909.9 KII89079.1 - 0.016 14.7 0.2 0.084 12.4 0.1 2.1 1 1 1 2 2 2 0 Amidohydrolase UPF0261 PF06792.6 KII89080.1 - 1.5e-130 435.3 5.7 1.8e-130 435.0 4.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Alba PF01918.16 KII89080.1 - 0.035 13.6 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Alba YTH PF04146.10 KII89081.1 - 3.9e-47 159.3 0.0 5.7e-47 158.8 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain p450 PF00067.17 KII89082.1 - 8.1e-70 235.6 0.0 9.3e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP_bind_3 PF01171.15 KII89083.1 - 4.6e-39 133.8 0.0 6.3e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Abhydrolase_6 PF12697.2 KII89084.1 - 9.7e-24 84.4 0.7 1.2e-23 84.1 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII89084.1 - 9.6e-13 48.1 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII89084.1 - 2.4e-11 43.6 0.0 9.3e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII89084.1 - 0.0011 18.2 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KII89084.1 - 0.0093 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 KII89084.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase FSH1 PF03959.8 KII89084.1 - 0.049 13.0 0.0 0.41 10.0 0.0 2.1 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KII89084.1 - 0.062 12.7 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 KII89084.1 - 0.15 11.7 0.0 15 5.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 KII89085.1 - 9.7e-24 84.5 0.9 1.3e-23 84.1 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII89085.1 - 1.8e-12 47.2 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII89085.1 - 7.8e-11 41.9 0.0 9.8e-10 38.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII89085.1 - 0.018 14.2 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KII89085.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KII89085.1 - 0.033 13.6 0.0 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 KII89085.1 - 0.12 11.7 0.0 0.56 9.6 0.0 2.0 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 KII89085.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein UPF0227 PF05728.7 KII89085.1 - 0.14 11.8 0.0 8 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) SRP40_C PF05022.7 KII89086.1 - 1.2e-26 92.9 0.8 1.3e-26 92.8 0.5 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain RSF PF14876.1 KII89086.1 - 0.0066 15.2 0.1 0.0069 15.2 0.1 1.0 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator DMRL_synthase PF00885.14 KII89087.1 - 1.5e-46 157.6 0.1 7.8e-27 93.7 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Gtr1_RagA PF04670.7 KII89088.1 - 1.5e-83 279.5 0.0 2.1e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KII89088.1 - 8.8e-08 31.7 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KII89088.1 - 3.8e-06 26.2 0.0 5.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KII89088.1 - 8.4e-06 25.7 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KII89088.1 - 8.7e-06 26.2 0.0 2.5e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein DUF1033 PF06279.6 KII89088.1 - 0.014 15.2 0.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) PduV-EutP PF10662.4 KII89088.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KII89088.1 - 0.098 12.2 0.5 0.2 11.2 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KII89088.1 - 0.11 12.4 0.1 1 9.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KII89088.1 - 0.13 12.2 0.2 17 5.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain Na_Ca_ex PF01699.19 KII89089.1 - 1.3e-43 147.9 29.4 4.7e-24 84.5 6.9 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KII89089.1 - 0.035 13.9 0.6 0.27 11.1 0.2 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) His_Phos_1 PF00300.17 KII89090.1 - 3.5e-27 95.4 0.0 2.9e-26 92.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1113 PF06541.6 KII89091.1 - 0.013 15.2 5.6 0.013 15.2 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1113) DUF3735 PF12537.3 KII89091.1 - 0.027 14.5 0.2 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) PFU PF09070.6 KII89092.1 - 6.6e-44 148.6 0.1 1.2e-43 147.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KII89092.1 - 1e-41 139.3 14.2 6.3e-09 35.3 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 KII89092.1 - 4.9e-27 94.3 0.0 7.3e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 KII89092.1 - 0.00022 20.9 0.1 1.1 9.0 0.0 2.9 1 1 2 3 3 3 3 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.13 KII89093.1 - 2.3e-41 141.5 0.0 3.9e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 HORMA domain MarR PF01047.17 KII89093.1 - 0.11 12.1 0.1 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 MarR family TFIIA PF03153.8 KII89094.1 - 0.44 10.3 5.5 0.64 9.8 3.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sybindin PF04099.7 KII89095.1 - 2.9e-39 134.0 0.0 3.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KII89095.1 - 6.7e-09 35.7 0.0 9.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Lipocalin_7 PF14651.1 KII89095.1 - 0.056 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_M28 PF04389.12 KII89096.1 - 5e-35 120.8 0.0 7.5e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 GET2 PF08690.5 KII89097.1 - 0.21 10.7 3.1 0.37 9.9 1.8 1.5 1 1 0 1 1 1 0 GET complex subunit GET2 PBP1_TM PF14812.1 KII89097.1 - 0.24 11.7 2.0 0.35 11.1 0.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RdRP PF05183.7 KII89098.1 - 5.3e-151 504.1 0.0 6.6e-151 503.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase PI3_PI4_kinase PF00454.22 KII89099.1 - 1.7e-37 129.1 0.1 1.2e-36 126.4 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KII89099.1 - 8.6e-23 80.4 0.1 3e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2937 PF11157.3 KII89103.1 - 0.11 11.8 1.1 0.2 10.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) zf-C2H2_jaz PF12171.3 KII89104.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KII89104.1 - 0.083 13.2 3.6 0.1 12.9 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KII89104.1 - 1.1 9.7 5.4 0.22 11.9 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type FA_hydroxylase PF04116.8 KII89105.1 - 1e-13 51.6 21.3 1e-13 51.6 14.7 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 KII89107.1 - 6.6e-05 23.2 6.9 0.00012 22.4 4.8 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Far-17a_AIG1 PF04750.9 KII89107.1 - 0.017 14.2 1.9 0.024 13.7 1.3 1.2 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein FA_hydroxylase PF04116.8 KII89108.1 - 0.00012 22.4 9.1 0.00013 22.3 6.3 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Far-17a_AIG1 PF04750.9 KII89108.1 - 0.01 14.9 3.8 0.013 14.7 2.6 1.2 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Cytochrome_CBB3 PF13442.1 KII89112.1 - 0.043 13.9 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III VitD-bind_III PF09164.5 KII89115.1 - 6.2 6.5 6.3 6.5 6.4 0.0 3.1 3 0 0 3 3 3 0 Vitamin D binding protein, domain III CPDase PF07823.6 KII89116.1 - 1.4e-19 70.3 0.0 2.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein DUF1776 PF08643.5 KII89116.1 - 4.4e-15 55.6 0.0 7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2_5_RNA_ligase2 PF13563.1 KII89116.1 - 5.2e-06 26.2 0.1 1.4e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF883 PF05957.8 KII89116.1 - 0.021 15.1 3.4 0.28 11.6 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Taq-exonuc PF09281.5 KII89116.1 - 0.04 14.0 0.5 0.15 12.2 0.1 1.9 1 1 1 2 2 2 0 Taq polymerase, exonuclease Mito_fiss_reg PF05308.6 KII89116.1 - 4.4 6.5 8.1 8.5 5.6 1.7 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Brix PF04427.13 KII89118.1 - 9.3e-38 129.8 0.1 1.2e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain zf-DHHC PF01529.15 KII89119.1 - 2.5e-21 75.8 0.1 7.5e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 KII89119.1 - 0.033 14.2 0.5 0.093 12.7 0.3 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SET PF00856.23 KII89120.1 - 2.6e-09 37.5 0.0 7.6e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KII89120.1 - 4.8e-07 29.5 16.2 1e-06 28.5 11.2 1.5 1 0 0 1 1 1 1 MYND finger IF-2B PF01008.12 KII89121.1 - 6.1e-63 212.4 0.1 7.3e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DNA_pol_B_3 PF08408.5 KII89121.1 - 0.12 12.2 0.3 0.38 10.6 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase family B viral insert LepA_C PF06421.7 KII89122.1 - 4.1e-41 139.2 1.4 5e-41 138.9 0.1 1.8 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 KII89122.1 - 6.1e-39 133.4 0.1 1.2e-38 132.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KII89122.1 - 5.9e-17 61.3 0.0 1.3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KII89122.1 - 3.3e-07 30.3 0.0 8.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KII89122.1 - 1.8e-05 24.4 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 KII89122.1 - 0.00021 20.7 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KII89122.1 - 0.0067 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KII89122.1 - 0.016 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KII89122.1 - 0.025 13.8 0.0 0.079 12.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SIS_2 PF13580.1 KII89122.1 - 0.029 14.0 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 0 SIS domain SRPRB PF09439.5 KII89122.1 - 0.031 13.4 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cwf18 PF08315.7 KII89123.1 - 8.1e-31 107.1 9.6 1.1e-30 106.7 6.6 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF3677 PF12432.3 KII89123.1 - 0.03 14.7 0.1 0.077 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Gti1_Pac2 PF09729.4 KII89124.1 - 1.4e-27 96.5 0.2 1.3e-25 90.1 0.2 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family Elongin_A PF06881.6 KII89125.1 - 1.5e-08 34.9 1.5 3e-08 33.9 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A FlhE PF06366.8 KII89127.1 - 0.0092 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Flagellar protein FlhE Ecl1 PF12855.2 KII89128.1 - 3.6e-05 22.9 0.7 6.6e-05 22.1 0.5 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Vps54 PF07928.7 KII89130.1 - 1.1e-50 171.2 2.7 2.6e-50 170.0 1.9 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.4 KII89130.1 - 0.00092 19.0 0.1 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 KII89130.1 - 0.0012 17.7 0.0 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec6 PF06046.8 KII89130.1 - 0.098 10.7 0.0 0.15 10.0 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 PPR PF01535.15 KII89130.1 - 0.16 11.9 0.0 0.52 10.4 0.0 1.8 1 0 0 1 1 1 0 PPR repeat DUF552 PF04472.7 KII89130.1 - 0.19 11.6 0.0 0.55 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF552) GST_C_3 PF14497.1 KII89131.1 - 7.5e-06 26.3 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII89131.1 - 0.00021 21.1 0.0 0.00064 19.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 KII89131.1 - 0.045 14.0 0.6 0.082 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2731) TRAM_LAG1_CLN8 PF03798.11 KII89132.1 - 1.2e-29 103.3 13.7 1.7e-29 102.8 9.5 1.2 1 0 0 1 1 1 1 TLC domain DUF4200 PF13863.1 KII89133.1 - 0.39 10.6 7.2 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PcfJ PF14284.1 KII89133.1 - 2.3 7.6 7.4 0.14 11.6 0.6 2.2 3 1 0 3 3 3 0 PcfJ-like protein G-gamma PF00631.17 KII89134.1 - 1.8e-25 88.4 0.0 2e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain COG5 PF10392.4 KII89134.1 - 0.1 12.5 0.4 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 G-gamma PF00631.17 KII89135.1 - 1.2e-17 63.4 2.8 1.2e-12 47.3 0.2 2.0 2 0 0 2 2 2 2 GGL domain Thioredoxin PF00085.15 KII89136.1 - 3.6e-23 81.2 0.0 4.5e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KII89136.1 - 2e-08 34.4 0.0 9.8e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII89136.1 - 3.1e-07 30.4 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KII89136.1 - 0.00015 21.6 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KII89136.1 - 0.007 16.0 0.0 0.0088 15.7 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII89136.1 - 0.021 14.3 0.1 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.1 KII89136.1 - 0.046 13.5 0.0 0.076 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.1 KII89136.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin Cu_bind_like PF02298.12 KII89138.1 - 0.00029 20.5 0.8 0.0019 17.9 0.5 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 KII89138.1 - 0.016 15.4 0.2 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF442 PF04273.8 KII89138.1 - 0.017 14.9 0.2 0.035 13.9 0.1 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) RAP1 PF07218.6 KII89138.1 - 0.67 7.9 6.2 0.83 7.6 4.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) KH_1 PF00013.24 KII89139.1 - 4.9e-39 131.7 8.2 2.8e-14 52.4 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KII89139.1 - 1.1e-29 101.5 13.2 1.1e-09 37.6 0.9 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KII89139.1 - 1.4e-15 56.5 5.6 2.2e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KII89139.1 - 4.8e-06 26.1 1.8 0.047 13.3 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KII89139.1 - 0.0018 18.0 4.8 4.1 7.2 0.0 3.5 3 0 0 3 3 3 3 NusA-like KH domain Sugar_tr PF00083.19 KII89140.1 - 6.4e-96 321.6 20.8 7.3e-96 321.4 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII89140.1 - 3.1e-35 121.5 42.5 7.4e-34 116.9 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KII89140.1 - 5.6e-07 27.9 6.6 0.01 13.9 0.0 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KII89140.1 - 0.0011 18.7 0.2 0.14 11.9 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family Phage_holin_2 PF04550.7 KII89140.1 - 0.025 14.6 2.8 0.097 12.7 1.9 2.0 1 0 0 1 1 1 0 Phage holin family 2 Glyoxal_oxid_N PF07250.6 KII89141.1 - 2.2e-50 170.9 0.0 7.9e-50 169.1 0.0 1.9 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KII89141.1 - 3e-20 72.1 0.1 9.2e-20 70.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) GATase_2 PF00310.16 KII89142.1 - 6e-26 91.0 0.1 1.7e-19 69.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 KII89142.1 - 2.2e-14 53.2 0.3 4e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 KII89142.1 - 5.5e-14 52.2 0.0 1.9e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KII89142.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KII89142.1 - 3.5e-05 22.6 0.0 9.3e-05 21.2 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II S-AdoMet_synt_C PF02773.11 KII89143.1 - 1.9e-76 254.3 0.3 3.6e-76 253.4 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KII89143.1 - 9.4e-49 164.3 0.0 1.7e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KII89143.1 - 4.6e-44 148.7 0.1 1e-43 147.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 KII89143.1 - 0.17 10.9 0.0 0.38 9.8 0.0 1.5 2 0 0 2 2 2 0 Amidinotransferase Myotub-related PF06602.9 KII89144.1 - 3.3e-129 430.6 0.2 4.7e-129 430.1 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KII89144.1 - 0.018 15.3 0.1 0.059 13.6 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 KII89144.1 - 0.035 13.6 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII89144.1 - 0.045 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KII89145.1 - 2e-26 92.1 0.0 2.4e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII89145.1 - 0.00086 18.7 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase A_deaminase PF00962.17 KII89146.1 - 4e-51 173.9 0.0 5.6e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KII89146.1 - 0.0012 18.7 0.0 0.0028 17.6 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal COMP PF11598.3 KII89146.1 - 0.041 13.9 0.3 0.088 12.8 0.2 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF812 PF05667.6 KII89147.1 - 0.0083 14.6 18.3 0.011 14.2 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4200 PF13863.1 KII89147.1 - 0.0096 15.8 2.1 0.0096 15.8 1.4 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 KII89147.1 - 0.046 13.4 11.8 0.35 10.6 0.2 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KII89147.1 - 0.69 9.7 18.1 2.5 7.9 1.6 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 KII89147.1 - 6.2 6.2 11.3 0.2 11.0 2.3 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Lzipper-MIP1 PF14389.1 KII89147.1 - 7.4 6.7 19.6 0.062 13.4 3.6 3.3 2 2 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TMF_TATA_bd PF12325.3 KII89147.1 - 8.9 6.0 18.6 6.8 6.4 2.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Trp_syntA PF00290.15 KII89148.1 - 2.9e-83 278.3 0.2 4.5e-83 277.7 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KII89148.1 - 2.7e-45 154.9 0.2 4.7e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 KII89148.1 - 2.2e-05 23.8 0.0 6.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 KII89148.1 - 0.0003 20.1 0.0 0.0032 16.7 0.1 2.2 2 0 0 2 2 2 1 PcrB family PA PF02225.17 KII89148.1 - 0.017 14.7 0.6 2.1 8.0 0.0 3.4 4 0 0 4 4 4 0 PA domain ThiG PF05690.9 KII89148.1 - 0.041 12.9 0.2 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG IGPS PF00218.16 KII89148.1 - 0.072 12.1 0.1 0.87 8.5 0.0 2.4 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase KH_1 PF00013.24 KII89149.1 - 2.4e-05 23.9 0.7 5.1e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 KH domain DUF3835 PF12927.2 KII89150.1 - 6.3e-12 46.2 1.3 6.3e-12 46.2 0.9 5.0 5 1 0 5 5 5 3 Domain of unknown function (DUF3835) Asparaginase PF00710.15 KII89151.1 - 3.6e-120 400.5 0.0 4.7e-120 400.1 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KII89151.1 - 2.6e-15 56.5 0.0 8.1e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KII89151.1 - 5.5e-15 54.3 2.1 3.3e-07 29.7 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KII89151.1 - 3.6e-10 39.7 0.4 2.1e-08 34.1 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII89151.1 - 5.1e-10 38.6 1.6 0.0023 17.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KII89151.1 - 3.8e-09 36.8 0.0 0.0015 19.0 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) GATase_7 PF13537.1 KII89151.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glyco_transf_22 PF03901.12 KII89152.1 - 1.8e-84 284.1 20.4 2.1e-84 283.9 14.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1713 PF08213.6 KII89153.1 - 9.7e-09 34.6 22.0 1.4e-08 34.1 15.3 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) gag-asp_proteas PF13975.1 KII89154.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease E1-E2_ATPase PF00122.15 KII89154.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase UQ_con PF00179.21 KII89155.1 - 3.8e-48 162.4 0.1 4.3e-48 162.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII89155.1 - 0.0061 16.3 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KII89155.1 - 0.052 13.4 1.1 0.094 12.6 0.7 1.7 1 1 0 1 1 1 0 RWD domain Ribosomal_L7Ae PF01248.21 KII89156.1 - 3.7e-25 87.2 0.0 4.4e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KII89156.1 - 0.00031 20.5 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KII89156.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Adenosine_kin PF04008.9 KII89156.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase Pax7 PF12360.3 KII89157.1 - 0.054 13.7 0.2 0.18 12.0 0.2 1.9 1 0 0 1 1 1 0 Paired box protein 7 Proteasome PF00227.21 KII89158.1 - 2.5e-51 173.6 0.1 3.1e-51 173.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FAD_binding_3 PF01494.14 KII89159.1 - 3.2e-51 174.4 0.0 7.6e-50 169.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII89159.1 - 2.2e-09 36.6 0.6 0.0006 18.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII89159.1 - 1.5e-07 31.7 0.0 3.5e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII89159.1 - 2.7e-05 24.4 0.3 0.069 13.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII89159.1 - 5.6e-05 21.7 0.6 0.15 10.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 KII89159.1 - 0.0014 17.5 0.4 0.0021 17.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KII89159.1 - 0.003 16.4 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KII89159.1 - 0.0038 17.1 0.3 0.017 15.0 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII89159.1 - 0.01 15.6 0.8 0.93 9.2 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KII89159.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 KII89159.1 - 0.012 15.4 0.2 0.024 14.4 0.2 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.1 KII89159.1 - 0.025 14.5 0.2 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KII89159.1 - 0.025 14.6 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KII89159.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_18 PF12847.2 KII89159.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KII89159.1 - 0.13 11.6 0.1 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 KII89159.1 - 0.16 11.0 0.5 0.59 9.1 0.2 1.8 1 1 1 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KII89159.1 - 0.17 10.7 0.8 2.8 6.7 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Syja_N PF02383.13 KII89160.1 - 1.3e-87 293.6 0.0 1.6e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KII89160.1 - 1.2e-23 82.7 0.0 2.1e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Pil1 PF13805.1 KII89160.1 - 3.8 6.5 7.1 16 4.5 0.0 2.4 2 0 0 2 2 2 0 Eisosome component PIL1 zf-C2H2 PF00096.21 KII89161.1 - 1.7e-05 24.8 1.4 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII89161.1 - 0.00038 20.5 2.4 0.066 13.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII89161.1 - 0.00038 20.5 0.5 0.11 12.6 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KII89161.1 - 0.061 13.4 1.4 0.82 9.8 1.1 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KII89161.1 - 0.17 11.9 1.6 1.9 8.6 1.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Abhydrolase_6 PF12697.2 KII89162.1 - 2.4e-13 50.4 0.2 5.4e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII89162.1 - 1.7e-05 24.5 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KII89162.1 - 0.00075 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.15 KII89162.1 - 0.00091 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 KII89162.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Apolipoprotein PF01442.13 KII89162.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Unstab_antitox PF09720.5 KII89162.1 - 1.3 8.7 6.5 9.9 5.9 0.2 2.7 2 0 0 2 2 2 0 Putative addiction module component GFO_IDH_MocA PF01408.17 KII89163.1 - 2e-13 50.8 0.0 3.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold LIM PF00412.17 KII89164.1 - 1.6e-18 66.5 23.2 1.1e-11 44.6 4.6 4.0 4 0 0 4 4 4 3 LIM domain AP_endonuc_2 PF01261.19 KII89165.1 - 1.6e-28 99.4 0.0 2.8e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF1308 PF07000.6 KII89165.1 - 0.065 11.8 0.1 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Mannitol_dh_C PF08125.8 KII89166.1 - 5.7e-50 169.7 0.0 8.1e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KII89166.1 - 1.7e-18 67.0 0.0 3.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 KII89166.1 - 0.00064 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KII89166.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KII89166.1 - 0.056 13.1 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_18 PF12847.2 KII89166.1 - 0.091 13.3 0.0 0.36 11.4 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Caerin_1 PF07440.7 KII89166.1 - 0.21 11.4 1.4 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Caerin 1 protein ABC_tran PF00005.22 KII89167.1 - 3.6e-16 59.7 0.0 6.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KII89167.1 - 0.00066 19.7 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KII89167.1 - 0.0016 19.2 0.0 0.0062 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII89167.1 - 0.0023 17.6 0.1 0.0074 16.0 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 KII89167.1 - 0.0029 17.8 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KII89167.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KII89167.1 - 0.0099 14.9 0.0 0.049 12.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 KII89167.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KII89167.1 - 0.013 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KII89167.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KII89167.1 - 0.027 14.4 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KII89167.1 - 0.028 13.9 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KII89167.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KII89167.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KII89167.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KII89167.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KII89167.1 - 0.075 13.5 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KII89167.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII89167.1 - 0.15 11.7 0.4 0.58 9.7 0.0 2.2 3 0 0 3 3 3 0 NACHT domain BTB PF00651.26 KII89169.1 - 0.00048 20.0 0.0 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain RPN7 PF10602.4 KII89170.1 - 2e-55 186.8 0.2 3e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KII89170.1 - 1.8e-17 63.5 0.9 6.7e-17 61.7 0.0 2.4 3 1 1 4 4 4 1 PCI domain PCI PF01399.22 KII89171.1 - 1.2e-17 64.0 1.1 2.1e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.1 KII89171.1 - 0.00051 19.6 0.8 13 5.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII89171.1 - 0.00062 19.3 6.7 0.081 12.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII89171.1 - 0.092 12.7 3.2 3.1 7.9 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII89171.1 - 0.28 11.5 9.4 3.8 7.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HMGL-like PF00682.14 KII89173.1 - 6.9e-58 196.0 0.0 1.1e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KII89173.1 - 8.3e-46 155.0 0.0 7.9e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain DUF3129 PF11327.3 KII89173.1 - 0.073 12.8 0.0 2.7 7.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3129) tRNA-synt_1c PF00749.16 KII89174.1 - 2.6e-103 344.9 0.0 3.5e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KII89174.1 - 2.3e-35 121.8 0.1 3.7e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KII89174.1 - 6.2e-07 29.8 0.5 2.1e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII89174.1 - 2.6e-06 27.2 0.1 6.7e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII89174.1 - 2.5e-05 24.1 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KII89174.1 - 0.1 11.7 0.1 0.23 10.5 0.1 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain HLH PF00010.21 KII89175.1 - 7.4e-12 44.7 0.4 1.6e-11 43.7 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HlyD PF00529.15 KII89175.1 - 1.2 8.3 9.6 3 7.0 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein APG9 PF04109.11 KII89178.1 - 1.7e-160 533.9 0.1 2.1e-160 533.6 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 EF-hand_4 PF12763.2 KII89179.1 - 6e-06 25.9 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF77 PF01910.12 KII89180.1 - 6.9e-29 99.3 0.0 8e-29 99.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 KII89180.1 - 8.8e-05 22.5 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DNA_methylase PF00145.12 KII89181.1 - 2.9e-48 164.7 0.0 4e-34 118.2 0.0 2.9 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 KII89181.1 - 8.2e-17 61.0 0.0 7e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 KII89181.1 - 6.3e-12 45.4 0.1 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BaffR-Tall_bind PF09256.5 KII89181.1 - 0.01 15.3 0.6 0.054 13.0 0.0 2.3 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding MCM PF00493.18 KII89182.1 - 3.7e-134 446.7 0.0 3.7e-133 443.4 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KII89182.1 - 1.1e-28 100.1 1.9 1.8e-28 99.4 0.4 2.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KII89182.1 - 6.6e-08 31.9 0.1 9.5e-06 24.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KII89182.1 - 8.9e-08 31.9 0.0 1.1e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KII89182.1 - 8.8e-05 22.8 0.2 0.00026 21.3 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KII89182.1 - 0.029 13.9 0.0 0.097 12.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KII89182.1 - 0.055 12.9 0.0 0.77 9.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain BLVR PF06375.6 KII89182.1 - 0.069 12.9 3.3 1.7 8.4 0.2 2.9 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S8 PF00082.17 KII89183.1 - 3.6e-50 170.7 1.6 5.1e-50 170.1 1.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KII89183.1 - 1.4e-27 95.2 0.1 2.4e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain PepSY_TM_2 PF13703.1 KII89183.1 - 0.066 13.3 0.3 0.23 11.6 0.2 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix POT1 PF02765.12 KII89184.1 - 7.9e-10 38.8 0.0 2.4e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TAP42 PF04177.7 KII89186.1 - 1.5e-76 257.6 0.0 1.6e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Cwf_Cwc_15 PF04889.7 KII89186.1 - 0.14 11.8 9.1 0.017 14.8 3.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ras PF00071.17 KII89187.1 - 1.6e-59 199.8 0.3 2e-59 199.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII89187.1 - 1.6e-22 80.1 0.2 3.1e-22 79.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KII89187.1 - 2.7e-16 59.2 0.1 3.4e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII89187.1 - 9e-08 31.7 0.2 6.3e-07 29.0 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KII89187.1 - 3.5e-07 29.6 0.6 4.4e-07 29.2 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KII89187.1 - 5.7e-07 28.9 0.1 1.2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KII89187.1 - 5.3e-06 26.3 0.1 2.3e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII89187.1 - 0.0014 17.9 0.6 0.095 11.9 0.4 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KII89187.1 - 0.0067 16.2 0.0 0.86 9.3 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 KII89187.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 KII89187.1 - 0.023 14.2 1.6 0.21 11.0 1.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KII89187.1 - 0.036 13.7 0.2 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CPT PF07931.7 KII89187.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 KII89187.1 - 0.065 13.1 0.6 0.11 12.3 0.2 1.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KII89187.1 - 0.096 12.8 0.0 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 KII89187.1 - 0.12 12.3 0.0 0.89 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MTHFR PF02219.12 KII89188.1 - 4.7e-103 344.2 0.0 6.8e-103 343.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Apc15p PF05841.6 KII89189.1 - 0.041 14.5 0.0 0.051 14.3 0.0 1.3 1 0 0 1 1 1 0 Apc15p protein WD40 PF00400.27 KII89190.1 - 8.4e-17 60.3 13.7 0.00028 20.6 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KII89190.1 - 0.0012 17.2 0.0 0.0044 15.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain Transket_pyr PF02779.19 KII89191.1 - 4.7e-40 136.9 0.0 6.3e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KII89191.1 - 1e-27 96.5 0.0 7.5e-27 93.7 0.0 2.3 2 1 0 2 2 2 1 Transketolase, C-terminal domain Peptidase_C1_2 PF03051.10 KII89191.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_S28 PF05577.7 KII89193.1 - 5.6e-57 193.2 0.0 3.5e-45 154.3 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abi PF02517.11 KII89194.1 - 5e-14 52.2 5.2 7.9e-14 51.5 2.7 2.0 3 0 0 3 3 3 1 CAAX protease self-immunity ATP-synt_ab PF00006.20 KII89195.1 - 1.1e-63 214.5 0.0 1.7e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KII89195.1 - 4.3e-24 85.1 0.4 7.3e-24 84.4 0.3 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KII89195.1 - 6.1e-22 77.6 4.0 6.1e-22 77.6 1.9 1.8 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 KII89195.1 - 0.014 14.2 0.9 0.03 13.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 KII89195.1 - 0.018 14.7 0.2 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KII89195.1 - 0.02 15.0 0.0 0.24 11.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KII89195.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 KII89195.1 - 0.028 13.5 0.1 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KII89195.1 - 0.028 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KII89195.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KII89195.1 - 0.034 13.5 0.1 0.071 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KII89195.1 - 0.039 13.0 0.1 0.074 12.1 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KII89195.1 - 0.049 13.6 0.2 0.14 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Pyr_redox_2 PF07992.9 KII89196.1 - 5.7e-23 81.8 0.0 8.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KII89196.1 - 1.4e-12 47.5 1.8 1.3e-07 31.6 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair Pyr_redox PF00070.22 KII89196.1 - 2.6e-11 43.7 0.0 3.2e-07 30.6 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KII89196.1 - 1.5e-10 39.5 1.4 6e-05 22.0 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KII89196.1 - 3.1e-08 32.8 0.9 0.00061 19.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KII89196.1 - 5.5e-08 32.2 1.6 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.1 KII89196.1 - 5.6e-07 29.8 0.0 0.22 11.5 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.1 KII89196.1 - 1.4e-05 24.1 0.6 0.0041 16.4 0.1 2.5 2 0 0 2 2 2 2 EF hand NAD_binding_7 PF13241.1 KII89196.1 - 0.0083 16.3 0.1 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KII89196.1 - 0.088 12.8 0.0 0.97 9.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Clp1 PF06807.9 KII89197.1 - 1.2e-19 70.9 0.0 6e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KII89197.1 - 3.4e-06 26.7 0.0 1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KII89197.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KII89197.1 - 0.072 13.9 0.0 0.18 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KII89197.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KII89197.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 KII89197.1 - 0.2 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KII89197.1 - 0.21 10.7 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KII89197.1 - 0.26 9.9 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit MFS_1 PF07690.11 KII89198.1 - 4e-26 91.5 30.3 4e-26 91.5 21.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 KII89199.1 - 1e-64 218.1 0.0 1.4e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89199.1 - 1.6e-36 125.7 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII89199.1 - 9.1e-09 34.6 0.0 1.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII89199.1 - 0.0012 18.6 0.4 0.0027 17.4 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII89199.1 - 0.057 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KII89199.1 - 0.12 11.4 0.5 0.27 10.2 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.24 KII89200.1 - 3.8e-12 46.5 0.0 7.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KII89200.1 - 1.1e-06 27.6 0.0 0.00041 19.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KII89200.1 - 0.00011 22.3 0.0 0.0019 18.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII89200.1 - 0.00024 20.2 0.0 0.00066 18.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KII89200.1 - 0.00024 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII89200.1 - 0.00034 20.3 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KII89200.1 - 0.00062 20.5 0.0 0.0016 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII89200.1 - 0.0017 18.2 0.1 0.014 15.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KII89200.1 - 0.0018 18.2 0.4 0.039 13.9 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KII89200.1 - 0.0052 16.4 0.1 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 KII89200.1 - 0.015 14.6 0.4 3.8 6.8 0.1 2.5 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KII89200.1 - 0.035 13.7 0.0 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 KII89200.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KII89200.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KII89200.1 - 0.087 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KII89200.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 KII89200.1 - 0.14 12.0 0.1 0.37 10.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 KII89200.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Aminotran_1_2 PF00155.16 KII89201.1 - 1.4e-12 47.2 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KII89201.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 KII89201.1 - 0.15 11.1 0.0 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase HSP70 PF00012.15 KII89202.1 - 7e-275 912.6 6.6 7.9e-275 912.4 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KII89202.1 - 5.6e-15 54.7 0.0 9.1e-14 50.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KII89202.1 - 0.0014 18.3 0.0 0.0051 16.4 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KII89202.1 - 0.013 14.5 0.7 0.084 11.9 0.0 2.4 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase TarH PF02203.10 KII89202.1 - 0.2 11.4 4.8 0.83 9.4 3.8 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue B56 PF01603.15 KII89203.1 - 1.8e-171 570.2 4.1 2.2e-171 570.0 2.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Citrate_synt PF00285.16 KII89205.1 - 2.9e-101 338.7 0.0 4.7e-101 338.0 0.0 1.3 2 0 0 2 2 2 1 Citrate synthase XH PF03469.9 KII89205.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 XH domain Sec66 PF09802.4 KII89206.1 - 1.2e-50 171.5 0.0 1.5e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 USP7_ICP0_bdg PF12436.3 KII89207.1 - 1.8e-84 282.8 0.1 6.4e-83 277.8 0.0 2.7 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KII89207.1 - 2.5e-66 223.1 3.2 9e-64 214.8 0.3 2.7 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KII89207.1 - 7.9e-57 192.4 0.1 1.2e-56 191.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII89207.1 - 6e-31 107.9 0.0 9e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KII89207.1 - 2.5e-07 30.9 0.1 3.4e-06 27.2 0.0 2.9 2 0 0 2 2 2 1 MATH domain Nol1_Nop2_Fmu PF01189.12 KII89210.1 - 4.8e-101 337.8 0.0 6e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 KII89210.1 - 0.00045 19.8 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 KII89210.1 - 0.0023 17.5 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KII89210.1 - 0.0053 16.3 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KII89210.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 KII89210.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SUR7 PF06687.7 KII89211.1 - 6.5e-24 84.6 15.5 8.9e-24 84.2 10.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF1689 PF07954.6 KII89211.1 - 0.0014 18.5 0.2 0.0022 17.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Abhydrolase_9_N PF15420.1 KII89211.1 - 0.032 13.9 4.9 0.059 13.1 3.4 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus YqjK PF13997.1 KII89211.1 - 0.57 10.4 2.3 1.7 8.9 0.1 2.5 3 0 0 3 3 3 0 YqjK-like protein Arch_flagellin PF01917.11 KII89211.1 - 0.98 9.0 3.4 0.6 9.7 0.2 1.8 2 0 0 2 2 2 0 Archaebacterial flagellin SHP PF03579.8 KII89211.1 - 8.1 5.8 6.7 0.55 9.6 0.1 2.2 2 0 0 2 2 2 0 Small hydrophobic protein Abhydrolase_6 PF12697.2 KII89213.1 - 2.7e-17 63.4 0.3 3.4e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KII89213.1 - 5.7e-17 61.3 0.5 2.3e-16 59.4 0.4 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KII89213.1 - 2.5e-15 56.4 0.0 4.4e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KII89213.1 - 0.00013 20.6 0.1 0.0055 15.2 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 KII89213.1 - 0.0097 15.3 0.2 0.4 10.0 0.0 2.3 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KII89213.1 - 0.019 14.5 0.1 0.078 12.5 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII89213.1 - 0.049 12.8 0.1 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 KII89213.1 - 0.079 12.2 0.1 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 KII89213.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Asn_synthase PF00733.16 KII89214.1 - 2.4e-71 240.2 0.1 3.1e-71 239.8 0.1 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KII89214.1 - 4.7e-36 123.2 0.0 7.8e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KII89214.1 - 5.3e-29 100.8 0.0 1.3e-28 99.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KII89214.1 - 1.9e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KII89214.1 - 0.0045 15.9 0.0 0.013 14.3 0.0 1.7 2 0 0 2 2 2 1 NAD synthase GATase_2 PF00310.16 KII89214.1 - 0.0047 15.6 0.0 0.23 10.1 0.0 2.3 1 1 2 3 3 3 1 Glutamine amidotransferases class-II QueC PF06508.8 KII89214.1 - 0.024 13.9 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TEA PF01285.13 KII89214.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 TEA/ATTS domain family RhoGEF PF00621.15 KII89215.1 - 7.4e-21 74.8 0.1 1e-16 61.3 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Methyltransf_16 PF10294.4 KII89216.1 - 3.7e-18 65.5 0.0 1.8e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KII89216.1 - 0.0012 19.3 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII89216.1 - 0.0099 15.9 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII89216.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3325 PF11804.3 KII89216.1 - 0.041 13.8 0.2 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3325) EF-hand_8 PF13833.1 KII89217.1 - 0.0027 17.3 0.2 0.0086 15.6 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF_assoc_2 PF08356.7 KII89217.1 - 0.015 15.0 0.1 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 EF hand associated EF_assoc_1 PF08355.7 KII89217.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 EF hand associated DEAD PF00270.24 KII89218.1 - 8.3e-42 142.5 0.0 6.7e-41 139.5 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII89218.1 - 8.9e-25 86.3 0.1 2e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KII89218.1 - 4.2e-05 22.4 0.0 6.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KII89218.1 - 0.021 14.6 0.2 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3421 PF11901.3 KII89218.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) DUF3334 PF11813.3 KII89218.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) CDP-OH_P_transf PF01066.16 KII89219.1 - 1.2e-11 44.7 4.1 1.2e-11 44.7 2.9 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4013 PF13197.1 KII89220.1 - 0.011 15.0 0.3 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF3158 PF11358.3 KII89220.1 - 0.045 13.2 0.1 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) HSA PF07529.8 KII89221.1 - 5.7e-16 58.0 0.2 5.7e-16 58.0 0.1 3.5 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.1 KII89221.1 - 5e-08 32.9 0.4 2.6e-07 30.6 0.3 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KII89221.1 - 0.0069 16.4 0.3 0.026 14.5 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3357 PF11837.3 KII89222.1 - 0.023 14.5 0.3 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) YjbE PF11106.3 KII89222.1 - 0.029 14.3 4.3 0.057 13.3 3.0 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE DUF2207 PF09972.4 KII89222.1 - 0.17 10.4 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cellulase PF00150.13 KII89223.1 - 1.6e-09 37.3 0.0 3.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) IATP PF04568.7 KII89224.1 - 3.2e-06 27.0 1.9 3.2e-06 27.0 1.4 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Ribonuclease_T2 PF00445.13 KII89225.1 - 9e-39 133.0 0.1 9e-39 133.0 0.0 1.3 2 0 0 2 2 2 1 Ribonuclease T2 family Aldedh PF00171.17 KII89226.1 - 1.2e-120 402.9 0.0 1.4e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cupredoxin_1 PF13473.1 KII89230.1 - 9.3e-05 22.2 0.1 0.031 14.1 0.0 2.6 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.15 KII89230.1 - 9.5e-05 22.5 1.6 0.18 12.0 0.1 2.7 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 KII89230.1 - 0.0087 15.8 9.1 0.94 9.3 0.5 3.9 2 2 0 2 2 2 2 Plastocyanin-like domain Kunitz_BPTI PF00014.18 KII89230.1 - 0.0099 16.0 1.3 1.3 9.3 0.1 2.4 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Glyco_hydro_59 PF02057.10 KII89230.1 - 0.051 11.6 0.0 1.4 6.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 DUF11 PF01345.13 KII89230.1 - 0.099 12.7 10.6 1.8 8.6 0.1 3.7 2 1 1 3 3 3 0 Domain of unknown function DUF11 DUF515 PF04415.7 KII89230.1 - 7.1 4.7 6.1 1.2 7.2 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF515) MUG113 PF13455.1 KII89231.1 - 1.2e-13 51.3 0.0 1.5e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KII89231.1 - 1e-07 32.2 0.0 8.7e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 T5orf172 domain Sas10_Utp3 PF04000.10 KII89232.1 - 3.1e-08 33.6 0.0 5.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family UDG PF03167.14 KII89233.1 - 7.7e-21 74.1 0.1 1.1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ERM PF00769.14 KII89234.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.15 KII89234.1 - 0.013 15.2 0.5 0.022 14.5 0.3 1.3 1 0 0 1 1 1 0 Prefoldin subunit Sugarporin_N PF11471.3 KII89234.1 - 0.067 12.8 1.2 0.15 11.7 0.8 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Prefoldin PF02996.12 KII89234.1 - 0.31 10.7 1.4 0.48 10.0 1.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit GrpE PF01025.14 KII89234.1 - 0.63 9.5 3.3 1.3 8.5 2.3 1.4 1 0 0 1 1 1 0 GrpE dsDNA_bind PF01984.15 KII89236.1 - 1.6e-23 82.7 10.1 1.9e-23 82.4 7.0 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.22 KII89236.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 PCI domain Host_attach PF10116.4 KII89236.1 - 0.24 11.6 2.9 0.37 11.0 1.8 1.5 1 1 0 1 1 1 0 Protein required for attachment to host cells Anophelin PF10731.4 KII89237.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito UCH_1 PF13423.1 KII89238.1 - 1.1e-50 172.8 0.0 1.8e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KII89238.1 - 2.3e-24 86.5 0.0 4.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KII89238.1 - 6.9e-08 31.9 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KII89238.1 - 0.023 14.5 3.4 1.7 8.6 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat FMO-like PF00743.14 KII89239.1 - 1.8e-40 138.6 0.0 5.5e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII89239.1 - 7.4e-22 78.4 0.0 1.6e-20 74.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KII89239.1 - 2.1e-08 33.4 0.0 9.8e-07 28.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII89239.1 - 9e-08 32.2 0.0 0.0012 18.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII89239.1 - 7.9e-07 28.9 0.0 2.2e-05 24.2 0.0 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KII89239.1 - 1.4e-06 28.1 0.0 0.00029 20.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII89239.1 - 1.6e-05 23.9 0.0 2 7.2 0.0 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KII89239.1 - 0.00097 19.2 0.5 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KII89239.1 - 0.0011 18.0 0.0 0.57 9.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 KII89239.1 - 0.0018 17.4 0.3 0.53 9.2 0.1 2.4 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 KII89239.1 - 0.0031 17.8 0.3 0.43 11.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KII89239.1 - 0.0038 17.4 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 KII89239.1 - 0.038 12.4 0.7 0.73 8.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein ELFV_dehydrog PF00208.16 KII89239.1 - 0.087 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KII89239.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KII89239.1 - 0.12 11.1 0.1 2.8 6.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain F420_oxidored PF03807.12 KII89239.1 - 0.2 12.1 0.1 0.86 10.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2618 PF10940.3 KII89240.1 - 0.014 15.1 1.8 0.022 14.4 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2618) CBFD_NFYB_HMF PF00808.18 KII89242.1 - 6e-21 74.2 1.1 8e-21 73.8 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KII89242.1 - 5.6e-09 36.0 0.0 7.7e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KII89242.1 - 0.0044 16.7 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 KII89242.1 - 0.073 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) F-box-like PF12937.2 KII89243.1 - 0.0022 17.7 1.1 0.0044 16.7 0.3 1.9 2 0 0 2 2 2 1 F-box-like CENP-F_leu_zip PF10473.4 KII89244.1 - 0.0047 16.7 0.2 0.0067 16.2 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KII89244.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-RING_4 PF14570.1 KII89246.1 - 4e-21 74.3 10.7 6.5e-21 73.6 7.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KII89246.1 - 0.00031 20.3 8.1 0.00053 19.5 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KII89246.1 - 0.0025 17.4 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 KII89246.1 - 0.036 14.0 12.6 0.063 13.3 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 KII89246.1 - 0.038 13.7 3.6 0.073 12.8 2.5 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.1 KII89246.1 - 0.044 13.5 2.8 0.11 12.3 1.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_5 PF13893.1 KII89246.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1272 PF06906.6 KII89246.1 - 2.6 7.9 7.4 4.9 7.0 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Cupin_8 PF13621.1 KII89247.1 - 4.8e-33 114.7 0.0 6.3e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KII89247.1 - 2.2e-05 23.9 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KII89247.1 - 0.0019 18.4 0.0 0.0057 16.8 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KII89247.1 - 0.0033 16.8 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KII89247.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF3535 PF12054.3 KII89248.1 - 2.9e-93 312.9 1.4 1.3e-92 310.7 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KII89248.1 - 1.7e-76 256.8 0.0 2.4e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KII89248.1 - 6.1e-15 53.9 11.4 1.1 9.5 0.0 10.0 9 0 0 9 9 9 6 HEAT repeat Helicase_C PF00271.26 KII89248.1 - 3.6e-12 45.9 0.0 7.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KII89248.1 - 0.00043 20.6 0.2 1.4 9.3 0.0 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KII89248.1 - 0.00075 19.7 12.5 0.33 11.2 0.1 6.8 6 2 0 6 6 6 2 HEAT repeats DUF1546 PF07571.8 KII89248.1 - 0.009 16.0 1.8 0.19 11.8 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 KII89248.1 - 0.017 15.5 24.3 11 6.6 0.0 9.7 10 1 1 11 11 11 0 HEAT-like repeat DUF3385 PF11865.3 KII89248.1 - 0.09 12.7 0.0 0.48 10.3 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) GPI-anchored PF10342.4 KII89249.1 - 2.3e-06 27.9 3.9 2.3e-06 27.9 2.7 2.4 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Herpes_gE PF02480.11 KII89249.1 - 0.048 11.9 1.5 0.061 11.5 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E CoA_trans PF01144.18 KII89250.1 - 3.3e-102 340.2 5.3 2.5e-61 206.6 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KII89250.1 - 0.00034 20.3 0.1 0.00076 19.1 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 KII89250.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain SMI1_KNR4 PF09346.5 KII89251.1 - 4.9e-23 81.5 0.0 8.6e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SOG2 PF10428.4 KII89252.1 - 9.1e-53 179.4 0.2 9.1e-53 179.4 0.1 3.4 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 KII89252.1 - 9.8e-12 44.2 5.3 7e-08 31.9 0.4 3.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII89252.1 - 1e-10 41.2 7.6 1.9e-06 27.4 1.0 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KII89252.1 - 2.4e-07 29.8 4.1 0.57 10.4 0.1 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KII89252.1 - 0.00012 21.6 4.0 5.8 7.5 0.0 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KII89252.1 - 0.049 13.7 4.3 3.4 8.0 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat CoA_trans PF01144.18 KII89253.1 - 3e-103 343.6 2.8 4.2e-60 202.6 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KII89253.1 - 0.00016 21.3 0.1 0.00039 20.1 0.1 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cofilin_ADF PF00241.15 KII89254.1 - 5.1e-18 65.1 0.0 9.7e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein FYVE PF01363.16 KII89255.1 - 7.5e-17 60.9 1.5 1.3e-16 60.1 1.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 KII89255.1 - 0.00023 20.6 0.4 0.00053 19.4 0.3 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.8 KII89255.1 - 0.018 14.7 4.9 0.018 14.7 3.4 1.9 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.11 KII89255.1 - 0.02 14.7 0.6 0.02 14.7 0.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4206 PF13901.1 KII89255.1 - 0.12 11.8 3.8 0.078 12.5 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) zf-RING_2 PF13639.1 KII89256.1 - 1.6e-05 24.5 14.3 3.3e-05 23.6 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII89256.1 - 2.7e-05 23.7 13.2 5.5e-05 22.7 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin_1 PF12718.2 KII89256.1 - 0.00036 20.4 6.8 0.00036 20.4 4.7 3.1 2 1 1 3 3 3 2 Tropomyosin like zf-C3HC4_2 PF13923.1 KII89256.1 - 0.00063 19.7 14.3 0.0013 18.7 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII89256.1 - 0.0012 18.4 14.2 0.0027 17.4 9.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain GAS PF13851.1 KII89256.1 - 0.0024 17.0 23.8 0.17 11.0 3.3 3.9 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding zf-C3HC4 PF00097.20 KII89256.1 - 0.0069 16.0 11.8 0.015 14.9 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FlxA PF14282.1 KII89256.1 - 0.12 12.3 14.0 0.98 9.3 0.7 4.3 4 1 0 4 4 4 0 FlxA-like protein AAA_13 PF13166.1 KII89256.1 - 0.12 10.8 17.2 0.0044 15.5 5.8 2.0 2 0 0 2 2 2 0 AAA domain zf-RING_4 PF14570.1 KII89256.1 - 0.14 11.7 11.1 0.3 10.7 7.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CENP-F_leu_zip PF10473.4 KII89256.1 - 0.24 11.2 22.3 0.19 11.5 1.4 4.1 3 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KII89256.1 - 0.26 10.8 26.5 0.28 10.7 0.2 3.7 2 1 1 3 3 3 0 IncA protein zf-UDP PF14569.1 KII89256.1 - 0.28 10.9 5.8 0.76 9.5 4.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.1 KII89256.1 - 0.41 10.4 9.7 1 9.1 6.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Filament PF00038.16 KII89256.1 - 0.65 9.4 29.6 0.23 10.8 2.8 3.3 2 1 1 3 3 3 0 Intermediate filament protein APG6 PF04111.7 KII89256.1 - 0.68 8.9 25.0 0.76 8.7 3.3 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 TBPIP PF07106.8 KII89256.1 - 0.76 9.2 14.0 0.38 10.2 0.2 3.8 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 KII89256.1 - 1.2 8.2 13.9 0.2 10.8 3.4 3.1 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KII89256.1 - 1.8 8.6 15.4 0.11 12.5 1.2 3.7 3 2 0 3 3 3 0 Fibrinogen alpha/beta chain family SPX PF03105.14 KII89256.1 - 2.3 7.9 8.0 2.3e+02 1.3 5.6 3.0 1 1 0 1 1 1 0 SPX domain TPR_MLP1_2 PF07926.7 KII89256.1 - 5.8 6.6 31.4 15 5.3 10.7 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glyco_hydro_88 PF07470.8 KII89257.1 - 1.2e-13 50.7 0.1 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 TBP PF00352.16 KII89258.1 - 2.4e-69 228.6 0.2 1.3e-34 117.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KII89258.1 - 0.00015 21.7 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Hamartin PF04388.7 KII89262.1 - 1.5 7.3 10.9 1.6 7.2 7.5 1.0 1 0 0 1 1 1 0 Hamartin protein EPL1 PF10513.4 KII89262.1 - 7.2 6.8 8.3 8.4 6.6 5.7 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like TBP PF00352.16 KII89263.1 - 1.3e-51 171.8 0.2 5.5e-35 118.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KII89263.1 - 0.00039 20.4 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) tRNA-synt_1b PF00579.20 KII89264.1 - 1.5e-19 70.2 0.0 3.5e-19 69.0 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-C3HC4_2 PF13923.1 KII89265.1 - 4.4e-09 36.2 10.1 4.4e-09 36.2 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII89265.1 - 9.6e-09 34.7 9.6 9.6e-09 34.7 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII89265.1 - 1.3e-08 34.5 9.0 1.3e-08 34.5 6.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KII89265.1 - 3.7e-08 33.0 3.1 3.7e-08 33.0 2.2 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 KII89265.1 - 6.8e-08 32.2 13.7 8.8e-08 31.8 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KII89265.1 - 8.4e-07 28.6 9.1 8.4e-07 28.6 6.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII89265.1 - 1e-06 28.2 11.1 1.3e-06 27.9 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KII89265.1 - 9.1e-05 22.3 0.0 0.0003 20.7 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-RING_UBOX PF13445.1 KII89265.1 - 9.6e-05 22.0 5.8 0.00011 21.8 2.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KII89265.1 - 0.00096 19.2 2.0 0.00096 19.2 1.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger Sgf11 PF08209.6 KII89265.1 - 0.052 12.8 0.3 0.16 11.2 0.2 1.8 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) TerY-C PF15616.1 KII89265.1 - 0.34 10.8 5.3 1.8 8.5 1.0 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain zf-Nse PF11789.3 KII89265.1 - 0.84 9.1 9.6 0.1 12.1 3.4 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.10 KII89265.1 - 0.93 8.9 5.8 0.5 9.8 1.5 2.3 2 0 0 2 2 2 0 RecR protein zf-RING_4 PF14570.1 KII89265.1 - 1.2 8.8 9.4 0.33 10.5 3.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 KII89265.1 - 2 8.3 6.4 0.98 9.3 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) NTF2 PF02136.15 KII89267.1 - 4e-34 117.5 0.1 4.5e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 KII89267.1 - 0.0078 15.2 0.1 0.01 14.9 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) S1-P1_nuclease PF02265.11 KII89268.1 - 1.9e-70 237.3 0.0 1.9e-69 234.1 0.0 1.9 1 1 0 1 1 1 1 S1/P1 Nuclease DUF1534 PF07551.6 KII89269.1 - 0.029 13.8 0.1 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) Dynamin_M PF01031.15 KII89271.1 - 2.7e-104 348.1 0.0 5.1e-104 347.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KII89271.1 - 1.8e-54 184.0 0.0 3.3e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KII89271.1 - 1.3e-27 95.5 3.5 3.2e-27 94.2 2.4 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KII89271.1 - 0.0022 17.9 0.1 0.027 14.4 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Lysine_decarbox PF03641.9 KII89272.1 - 9.7e-33 112.8 0.0 1.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Dimer_Tnp_hAT PF05699.9 KII89273.1 - 0.00088 18.8 0.0 0.003 17.1 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.10 KII89273.1 - 0.0041 16.6 0.1 0.0073 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) F-box-like PF12937.2 KII89274.1 - 2.3e-06 27.2 0.7 7.2e-06 25.6 0.5 1.9 1 0 0 1 1 1 1 F-box-like CD52 PF15116.1 KII89274.1 - 1.1 9.1 5.1 2.8 7.8 3.5 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen Cullin_binding PF03556.10 KII89276.1 - 2e-24 85.9 0.3 4.2e-24 84.9 0.1 1.6 2 0 0 2 2 2 1 Cullin binding Mitofilin PF09731.4 KII89276.1 - 0.18 10.3 5.8 0.19 10.3 4.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF59 PF01883.14 KII89277.1 - 4.7e-11 42.5 0.1 1e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 CNRIP1 PF15043.1 KII89277.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 OCD_Mu_crystall PF02423.10 KII89278.1 - 5.9e-29 100.8 2.0 3.7e-22 78.4 0.4 3.2 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family ADH_zinc_N PF00107.21 KII89279.1 - 7.8e-08 31.9 0.6 2.3e-06 27.1 0.4 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 KII89279.1 - 0.051 13.4 0.8 0.089 12.7 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 KII89280.1 - 1.1e-23 84.5 0.2 2.7e-23 83.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KII89280.1 - 6.8e-14 51.5 0.1 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89280.1 - 0.0019 17.9 0.0 0.017 14.8 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Hat1_N PF10394.4 KII89281.1 - 7.7e-41 139.8 0.0 1.4e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 KII89281.1 - 0.00077 19.4 0.4 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII89281.1 - 0.00094 19.2 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KII89281.1 - 0.002 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family HCaRG PF07258.9 KII89281.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 HCaRG protein Acetyltransf_7 PF13508.1 KII89281.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3415 PF11895.3 KII89281.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) DUF948 PF06103.6 KII89282.1 - 0.23 11.3 0.9 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ERM PF00769.14 KII89282.1 - 0.46 9.9 40.0 0.015 14.8 8.7 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family GAS PF13851.1 KII89282.1 - 1.1 8.4 22.1 0.07 12.3 5.6 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KII89282.1 - 1.1 8.7 19.2 4.3 6.8 2.4 4.5 2 1 2 4 4 4 0 Septum formation initiator AAA_13 PF13166.1 KII89282.1 - 1.9 6.8 12.2 2.5 6.4 8.5 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 KII89282.1 - 2.2 8.6 20.6 9.6 6.6 3.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KII89282.1 - 2.5 8.4 25.1 4.2 7.7 0.5 4.3 2 1 1 3 3 3 0 Protein of unknown function (DUF904) NYD-SP28_assoc PF14775.1 KII89282.1 - 3.3 7.4 11.2 0.08 12.6 1.0 2.8 3 0 0 3 3 3 0 Sperm tail C-terminal domain APG6 PF04111.7 KII89282.1 - 7.1 5.5 26.7 6.5 5.6 6.3 2.4 1 1 2 3 3 3 0 Autophagy protein Apg6 Rad1 PF02144.11 KII89284.1 - 4.3e-66 222.5 0.0 2.5e-39 134.7 0.0 2.0 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Biotin_lipoyl PF00364.17 KII89285.1 - 3.1e-19 68.3 1.0 5.9e-19 67.4 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KII89285.1 - 2.1e-07 30.4 1.2 1.7e-06 27.5 0.0 2.7 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KII89285.1 - 0.052 13.2 0.7 0.36 10.5 0.0 2.5 3 0 0 3 3 3 0 Biotin-lipoyl like QRPTase_N PF02749.11 KII89285.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2360 PF10152.4 KII89285.1 - 1.1 9.5 6.7 1.6 9.0 1.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 KII89285.1 - 7.2 5.8 9.5 0.13 11.6 1.7 1.7 2 0 0 2 2 2 0 Vta1 like Sterol-sensing PF12349.3 KII89286.1 - 1.3e-33 115.6 11.4 1.3e-33 115.6 7.9 2.3 1 1 1 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KII89286.1 - 5.3e-14 51.1 5.8 7.3e-14 50.6 4.0 1.1 1 0 0 1 1 1 1 Patched family DUF3796 PF12676.2 KII89286.1 - 0.15 12.3 7.2 0.22 11.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Nop14 PF04147.7 KII89288.1 - 0.0091 13.9 10.6 0.012 13.5 7.4 1.2 1 0 0 1 1 1 1 Nop14-like family Cwf_Cwc_15 PF04889.7 KII89288.1 - 0.12 12.0 14.2 0.12 12.0 8.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 KII89288.1 - 7.1 6.0 19.9 0.35 10.3 10.0 1.6 2 0 0 2 2 2 0 PPP4R2 DUF1658 PF07871.6 KII89290.1 - 0.0032 17.0 0.7 0.033 13.7 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1658) DUF1405 PF07187.6 KII89291.1 - 0.045 13.4 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) PI-PLC-X PF00388.14 KII89292.1 - 2.6e-08 33.3 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain adh_short PF00106.20 KII89293.1 - 8.3e-21 74.6 0.4 1.5e-20 73.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII89293.1 - 1.4e-07 31.3 0.1 2.1e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII89293.1 - 9.4e-05 21.9 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII89293.1 - 0.00049 20.1 0.2 0.00089 19.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KII89293.1 - 0.0017 18.1 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 KII89293.1 - 0.0027 16.8 0.0 0.0051 15.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KII89293.1 - 0.055 13.5 0.1 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KII89295.1 - 4e-37 128.0 0.0 8.3e-37 127.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KII89295.1 - 1.5e-34 118.2 0.2 3e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KII89295.1 - 6.6e-22 77.7 4.3 1.2e-18 67.2 0.3 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII89295.1 - 2.7e-15 56.9 0.0 3.3e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII89295.1 - 5.3e-07 28.4 2.1 0.0042 15.6 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 KII89295.1 - 2.9e-06 26.6 0.1 6.1e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KII89295.1 - 2.2e-05 23.5 0.0 6.5e-05 22.0 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KII89295.1 - 0.0011 18.9 1.0 0.0011 18.9 0.7 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII89295.1 - 0.0016 17.3 4.5 0.014 14.2 1.6 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KII89295.1 - 0.0035 16.2 1.2 0.03 13.1 0.5 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KII89295.1 - 0.024 14.3 0.6 0.21 11.3 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KII89295.1 - 0.044 13.4 2.6 0.2 11.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KII89295.1 - 0.05 12.6 1.1 0.15 11.1 0.2 2.2 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 KII89295.1 - 0.081 11.8 9.5 0.32 9.8 0.3 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII89295.1 - 3.4 6.6 7.8 34 3.3 0.1 3.6 3 1 1 4 4 4 0 FAD binding domain PDE8 PF08629.5 KII89296.1 - 0.013 15.3 0.4 0.05 13.3 0.1 2.1 2 0 0 2 2 2 0 PDE8 phosphodiesterase MIF PF01187.13 KII89297.1 - 3.6e-19 68.9 0.0 4.2e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.13 KII89298.1 - 2.9e-18 66.0 0.0 3.2e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Rpp20 PF12328.3 KII89299.1 - 2.1e-06 27.4 0.0 3.3e-05 23.5 0.0 2.4 2 1 1 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P eRF1_2 PF03464.10 KII89300.1 - 1.1e-44 151.9 0.0 2.4e-44 150.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KII89300.1 - 6.8e-39 132.6 0.5 1.4e-38 131.6 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KII89300.1 - 2e-26 92.1 0.0 4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Pro-kuma_activ PF09286.6 KII89301.1 - 1e-36 126.0 0.1 1.8e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII89301.1 - 3.1e-08 33.1 0.0 5.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Amidohydro_4 PF13147.1 KII89304.1 - 3.3e-17 63.4 0.8 8.7e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KII89304.1 - 1.3e-11 44.1 0.1 3.6e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KII89304.1 - 1.6e-11 44.4 0.1 5e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.7 KII89304.1 - 2.3e-07 30.3 0.1 0.0072 15.9 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Amidohydro_3 PF07969.6 KII89304.1 - 1.2e-05 24.7 0.1 0.0066 15.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Potex_coat PF06184.6 KII89305.1 - 0.048 13.0 0.2 0.11 11.9 0.2 1.6 1 1 0 1 1 1 0 Potexvirus coat protein RRM_1 PF00076.17 KII89306.1 - 2.2e-33 113.6 0.0 4.1e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII89306.1 - 7.5e-16 57.8 0.0 4.1e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII89306.1 - 5.8e-09 35.6 0.0 0.002 17.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KII89306.1 - 0.061 12.8 0.2 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain IL13 PF03487.8 KII89307.1 - 0.043 13.5 5.2 0.61 9.8 0.2 3.1 3 0 0 3 3 3 0 Interleukin-13 Ras PF00071.17 KII89308.1 - 7.4e-54 181.5 0.0 8.5e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII89308.1 - 8.8e-16 58.4 0.0 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII89308.1 - 3.3e-07 29.7 0.0 4.4e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family WD40 PF00400.27 KII89309.1 - 1.1e-10 40.9 1.3 1.8e-05 24.4 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat EF-1_beta_acid PF10587.4 KII89310.1 - 0.25 11.5 2.0 0.43 10.7 1.4 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF1077 PF06417.7 KII89311.1 - 7e-43 144.9 0.0 8.6e-43 144.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Senescence PF06911.7 KII89312.1 - 3.1e-18 66.1 8.3 9.4e-18 64.5 5.7 1.7 1 1 0 1 1 1 1 Senescence-associated protein VGCC_alpha2 PF08473.6 KII89312.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd Phosducin PF02114.11 KII89313.1 - 2.7e-08 32.8 0.0 5.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Phosducin Pox_Ag35 PF03286.9 KII89313.1 - 0.86 9.0 6.7 9.6 5.6 2.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ribonuclease_3 PF00636.21 KII89314.1 - 3.5e-39 133.7 0.0 1.5e-19 70.5 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KII89314.1 - 1e-25 90.1 0.0 1.5e-15 57.2 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.26 KII89314.1 - 2e-13 49.9 0.0 4.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KII89314.1 - 7.3e-11 41.7 0.0 2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 KII89314.1 - 0.0049 16.7 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KII89314.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase PAZ PF02170.17 KII89314.1 - 0.036 13.3 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 PAZ domain dsrm PF00035.20 KII89314.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif CMD PF02627.15 KII89315.1 - 0.015 15.1 0.4 0.066 13.0 0.2 2.1 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family TrbE PF11100.3 KII89316.1 - 0.074 12.9 0.3 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Conjugal transfer protein TrbE Ras PF00071.17 KII89317.1 - 1.3e-61 206.7 0.2 1.6e-61 206.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII89317.1 - 1.7e-20 73.7 0.0 2.3e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII89317.1 - 7.5e-12 44.8 0.0 9.3e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KII89317.1 - 1.3e-07 31.5 0.1 2.1e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KII89317.1 - 4.6e-05 23.5 0.0 0.00017 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KII89317.1 - 5.7e-05 22.6 0.1 0.00016 21.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 KII89317.1 - 0.0022 17.1 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KII89317.1 - 0.0027 16.9 0.0 0.007 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 KII89317.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KII89317.1 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KII89317.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KII89317.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KII89317.1 - 0.024 13.9 0.2 0.099 11.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 KII89317.1 - 0.028 14.6 0.1 0.046 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KII89317.1 - 0.047 13.6 0.1 0.088 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KII89317.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain YvfG PF09628.5 KII89317.1 - 0.12 12.4 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.9 KII89317.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Oxidored_FMN PF00724.15 KII89318.1 - 1.9e-72 244.1 0.0 2.5e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF442 PF04273.8 KII89318.1 - 0.097 12.5 0.2 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 Putative phosphatase (DUF442) ABC_tran PF00005.22 KII89319.1 - 1.3e-42 145.3 0.1 2.3e-20 73.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII89319.1 - 2.4e-14 53.9 7.9 8.3e-05 22.6 0.8 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KII89319.1 - 3.4e-13 49.3 0.4 0.00093 18.4 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KII89319.1 - 1.7e-08 33.8 0.2 0.007 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 KII89319.1 - 1.4e-07 31.6 12.6 0.0033 17.6 0.1 4.0 1 1 2 3 3 3 3 HEAT repeats AAA_17 PF13207.1 KII89319.1 - 2.1e-07 31.7 0.1 0.0011 19.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KII89319.1 - 1.8e-06 28.1 0.0 0.02 15.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KII89319.1 - 4.5e-06 26.3 0.2 0.017 14.5 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain DUF87 PF01935.12 KII89319.1 - 4.9e-06 26.5 0.0 0.0026 17.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KII89319.1 - 6e-06 26.7 0.1 0.087 13.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 KII89319.1 - 6.9e-06 25.8 0.1 0.13 11.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.1 KII89319.1 - 1.7e-05 24.6 0.3 0.028 14.3 0.0 3.3 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KII89319.1 - 2e-05 24.3 0.1 0.19 11.4 0.0 3.6 4 0 0 4 4 4 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KII89319.1 - 2.2e-05 23.7 0.1 0.06 12.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Chromo PF00385.19 KII89319.1 - 2.9e-05 23.6 0.1 7.6e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_18 PF13238.1 KII89319.1 - 3.3e-05 24.1 0.4 0.028 14.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII89319.1 - 4.7e-05 23.5 0.0 0.21 11.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_25 PF13481.1 KII89319.1 - 6.3e-05 22.4 0.0 0.21 10.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KII89319.1 - 0.00011 22.1 2.0 0.18 11.7 0.0 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase HEAT PF02985.17 KII89319.1 - 0.00019 21.2 6.2 0.11 12.6 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat AAA PF00004.24 KII89319.1 - 0.00027 21.1 0.0 2 8.5 0.0 3.5 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KII89319.1 - 0.00029 21.2 8.9 0.033 14.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain ArgK PF03308.11 KII89319.1 - 0.00031 19.5 0.1 0.34 9.6 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 KII89319.1 - 0.00035 20.4 0.0 0.67 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KII89319.1 - 0.00041 19.5 0.4 3.4 6.5 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 KII89319.1 - 0.00044 20.2 0.0 0.71 9.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 KII89319.1 - 0.00077 19.2 0.2 3.4 7.2 0.0 3.5 3 0 0 3 3 3 1 Archaeal ATPase HEAT_EZ PF13513.1 KII89319.1 - 0.00098 19.5 12.6 0.096 13.2 1.4 5.5 4 1 1 5 5 5 1 HEAT-like repeat AAA_13 PF13166.1 KII89319.1 - 0.0032 16.0 0.0 1.9 6.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 KII89319.1 - 0.006 15.5 0.1 2.2 7.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Dynamin_N PF00350.18 KII89319.1 - 0.0061 16.3 0.0 0.24 11.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 KII89319.1 - 0.011 15.2 1.7 0.79 9.1 0.0 3.0 4 0 0 4 4 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KII89319.1 - 0.013 15.4 0.3 3.8 7.4 0.1 3.6 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KII89319.1 - 0.013 15.4 12.6 0.02 14.8 0.3 4.3 4 1 0 4 4 3 0 AAA ATPase domain KAP_NTPase PF07693.9 KII89319.1 - 0.037 13.0 0.4 0.18 10.7 0.0 2.3 3 0 0 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.10 KII89319.1 - 0.039 13.6 0.0 6.6 6.4 0.0 2.7 2 0 0 2 2 2 0 NTPase cobW PF02492.14 KII89319.1 - 0.074 12.4 2.3 6.3 6.2 0.0 3.5 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 KII89319.1 - 0.13 11.7 0.0 4.1 6.8 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 KII89319.1 - 0.41 10.3 4.4 11 5.7 0.1 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) V_ATPase_I PF01496.14 KII89320.1 - 2.6e-281 934.9 0.0 3e-281 934.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Wzz PF02706.10 KII89320.1 - 0.039 13.7 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Chain length determinant protein SlyX PF04102.7 KII89320.1 - 0.089 13.1 3.7 0.12 12.7 0.8 2.4 3 0 0 3 3 3 0 SlyX Clusterin PF01093.12 KII89320.1 - 0.25 10.1 0.5 0.38 9.4 0.3 1.2 1 0 0 1 1 1 0 Clusterin Lactamase_B PF00753.22 KII89321.1 - 2.2e-20 73.1 3.6 5.6e-20 71.8 2.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KII89321.1 - 1.9e-06 27.5 0.1 2.6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VCBS PF13517.1 KII89322.1 - 1e-22 80.2 19.6 2.2e-08 34.2 1.7 5.7 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KII89322.1 - 4e-13 48.6 13.4 0.0064 16.1 0.3 6.5 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 KII89322.1 - 0.00094 18.6 9.4 3.6 6.9 0.1 6.3 4 2 2 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region Peptidase_M50B PF13398.1 KII89323.1 - 3.8e-54 183.1 20.7 5.3e-54 182.6 14.3 1.1 1 0 0 1 1 1 1 Peptidase M50B-like FAD_binding_3 PF01494.14 KII89324.1 - 5.5e-21 75.0 1.3 2.7e-20 72.7 0.9 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII89324.1 - 1.9e-06 27.0 0.3 4.1e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII89324.1 - 2.1e-06 27.6 1.0 4.8e-06 26.5 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII89324.1 - 5.3e-05 22.2 0.4 7.8e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KII89324.1 - 6.9e-05 23.1 0.2 0.00016 22.0 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII89324.1 - 0.00027 19.9 1.6 0.0005 19.0 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KII89324.1 - 0.00078 19.3 0.6 0.0018 18.1 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KII89324.1 - 0.0013 18.3 0.2 0.0025 17.3 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KII89324.1 - 0.0025 16.7 1.2 0.004 16.0 0.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII89324.1 - 0.0081 15.2 2.8 0.013 14.6 1.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII89324.1 - 0.058 12.4 0.2 0.058 12.4 0.2 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 KII89324.1 - 0.069 12.2 0.1 0.2 10.6 0.1 1.7 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KII89324.1 - 0.091 11.2 1.4 0.14 10.5 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KII89324.1 - 0.12 12.4 0.3 0.31 11.0 0.3 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KII89324.1 - 0.15 10.6 2.9 3.3 6.2 0.6 2.9 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.13 KII89324.1 - 1.4 8.5 5.1 0.26 10.9 0.6 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SnoaL_2 PF12680.2 KII89325.1 - 1.9e-05 24.9 0.1 3.6e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KII89325.1 - 3e-05 23.6 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase MIF4G PF02854.14 KII89326.1 - 3.3e-27 95.2 0.3 4.3e-26 91.6 0.0 2.5 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KII89326.1 - 4.6e-22 77.8 0.0 9.9e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 MA3 domain DNA_pol_phi PF04931.8 KII89326.1 - 2.2 5.9 10.5 3.2 5.4 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cerato-platanin PF07249.7 KII89328.1 - 5.4e-33 113.5 1.3 6.4e-33 113.2 0.9 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 KII89328.1 - 0.035 13.7 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Barwin family DDE_3 PF13358.1 KII89329.1 - 2.1e-11 43.7 0.3 4e-10 39.5 0.1 2.8 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF2441 PF10386.4 KII89329.1 - 0.0058 16.6 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2441) Exonuc_V_gamma PF04257.9 KII89329.1 - 0.024 12.6 0.0 0.034 12.1 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit HTH_33 PF13592.1 KII89329.1 - 0.079 12.5 0.3 0.26 10.8 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Sarcoglycan_2 PF05510.8 KII89335.1 - 0.12 10.6 0.0 0.22 9.7 0.0 1.4 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Cyt_c_ox_IV PF12270.3 KII89335.1 - 5.9 6.6 9.4 6.9 6.4 1.7 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV LRV_FeS PF05484.6 KII89336.1 - 0.047 13.2 0.4 0.095 12.2 0.3 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster Isochorismatase PF00857.15 KII89337.1 - 2.9e-35 121.7 0.0 3.3e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family GAS PF13851.1 KII89339.1 - 0.00015 21.0 3.6 0.00025 20.3 2.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 KII89339.1 - 8 6.4 10.9 3 7.8 5.3 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_11 PF13414.1 KII89340.1 - 9.6e-13 47.5 3.4 3.3e-11 42.6 0.1 2.5 2 0 0 2 2 2 1 TPR repeat F-box-like PF12937.2 KII89340.1 - 1.1e-12 47.4 0.5 7.8e-12 44.7 0.3 2.2 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.23 KII89340.1 - 1.6e-08 33.7 0.1 0.00054 19.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII89340.1 - 8.9e-07 28.3 1.5 0.0015 18.3 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.28 KII89340.1 - 0.0001 21.8 0.1 0.0014 18.2 0.0 2.5 2 0 0 2 2 2 1 F-box domain TPR_8 PF13181.1 KII89340.1 - 0.00028 20.4 1.3 0.35 10.7 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII89340.1 - 0.00029 20.7 1.3 0.00051 19.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII89340.1 - 0.00073 20.1 8.8 0.0028 18.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KII89340.1 - 0.0062 16.6 2.3 0.13 12.5 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII89340.1 - 0.016 15.0 5.2 0.15 11.9 0.1 2.8 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 KII89340.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.1 KII89340.1 - 0.25 12.0 8.1 2.2 9.1 0.4 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII89340.1 - 0.25 11.6 4.7 0.9 9.9 0.8 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyoxalase_3 PF13468.1 KII89341.1 - 1.5e-30 106.3 0.0 8.8e-30 103.8 0.0 1.8 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KII89341.1 - 0.0057 16.6 0.0 0.8 9.7 0.0 2.9 2 1 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Asp PF00026.18 KII89342.1 - 4.9e-82 275.6 11.6 5.9e-82 275.4 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KII89342.1 - 0.00018 21.0 0.1 0.00046 19.7 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KII89342.1 - 0.00029 20.8 6.9 0.00033 20.6 2.5 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII89342.1 - 0.00058 20.3 2.6 0.44 11.0 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease WD40 PF00400.27 KII89343.1 - 1.1e-59 196.2 17.8 1.7e-10 40.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KII89343.1 - 1.3e-09 38.0 0.5 4e-05 23.3 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KII89343.1 - 6.3e-05 21.8 0.3 2.4 6.7 0.0 4.0 1 1 0 2 2 2 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 KII89343.1 - 0.00055 18.8 0.0 0.00076 18.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Det1 PF09737.4 KII89343.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Apc4_WD40 PF12894.2 KII89343.1 - 0.017 14.6 0.0 2 7.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 KII89343.1 - 0.044 12.0 0.0 0.22 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 KII89343.1 - 0.092 10.5 0.0 0.16 9.7 0.0 1.3 1 0 0 1 1 1 0 IKI3 family CBM_21 PF03370.8 KII89344.1 - 5e-27 94.1 0.0 8.8e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit zf-MYND PF01753.13 KII89345.1 - 9.9e-10 38.1 12.2 1.5e-09 37.5 8.5 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII89345.1 - 0.0019 18.0 4.4 0.004 16.9 3.1 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 KII89345.1 - 0.36 10.5 6.6 0.69 9.6 4.6 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.13 KII89347.1 - 7.9e-08 32.0 9.2 1.3e-07 31.3 6.4 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KII89347.1 - 0.024 14.2 5.9 0.041 13.5 4.1 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.1 KII89347.1 - 0.88 9.4 8.4 2.8 7.8 5.8 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 KAP PF05804.7 KII89348.1 - 0.11 10.3 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Zn_clus PF00172.13 KII89349.1 - 4.7e-07 29.6 15.4 1.1e-06 28.3 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII89349.1 - 2.8e-05 23.1 0.2 4.7e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FlxA PF14282.1 KII89349.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 FlxA-like protein Golgin_A5 PF09787.4 KII89349.1 - 0.18 10.2 0.1 0.31 9.5 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Clusterin PF01093.12 KII89349.1 - 0.99 8.1 3.4 1.5 7.5 2.4 1.2 1 0 0 1 1 1 0 Clusterin ADK PF00406.17 KII89350.1 - 5.9e-58 195.0 0.0 7.3e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KII89350.1 - 6.9e-15 54.4 0.0 1.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KII89350.1 - 0.01 16.6 0.0 0.018 15.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KII89350.1 - 0.045 12.8 0.1 0.082 11.9 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KII89350.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DDOST_48kD PF03345.9 KII89351.1 - 2.4e-107 359.1 0.0 2.9e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BCSC_C PF05420.6 KII89351.1 - 0.03 13.4 0.3 0.056 12.5 0.0 1.4 2 0 0 2 2 2 0 Cellulose synthase operon protein C C-terminus (BCSC_C) DUF446 PF04287.7 KII89357.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 tRNA pseudouridine synthase C Pkinase PF00069.20 KII89359.1 - 2.3e-51 174.4 0.0 3.1e-50 170.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89359.1 - 5.5e-27 94.4 0.0 2.1e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KII89359.1 - 5.3e-05 22.3 0.1 8.5e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII89359.1 - 9.7e-05 21.4 0.0 0.003 16.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII89359.1 - 0.015 15.0 2.3 2 8.1 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family GPDPase_memb PF10110.4 KII89360.1 - 0.054 12.9 8.7 0.097 12.0 6.0 1.4 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Herpes_LMP1 PF05297.6 KII89360.1 - 0.32 9.8 6.1 0.42 9.4 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) HemY_N PF07219.8 KII89360.1 - 2.7 7.6 8.3 1.4 8.5 4.0 2.0 1 1 1 2 2 2 0 HemY protein N-terminus LMBR1 PF04791.11 KII89361.1 - 0.089 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cerato-platanin PF07249.7 KII89363.1 - 4.8e-23 81.4 3.8 3.1e-22 78.8 2.6 1.9 1 1 0 1 1 1 1 Cerato-platanin Pkinase PF00069.20 KII89365.1 - 9.3e-35 120.0 0.0 1e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89365.1 - 2.1e-12 46.6 0.0 2.4e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII89365.1 - 1.7e-05 24.0 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII89365.1 - 1.8e-05 23.8 0.0 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KII89365.1 - 0.044 13.5 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cerato-platanin PF07249.7 KII89371.1 - 2.4e-41 140.4 2.2 2.9e-41 140.2 1.5 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 KII89371.1 - 0.005 16.4 0.4 0.0077 15.9 0.3 1.4 1 1 0 1 1 1 1 Barwin family Glyco_hydro_45 PF02015.11 KII89371.1 - 0.025 14.6 0.7 0.029 14.4 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Cerato-platanin PF07249.7 KII89372.1 - 5.1e-34 116.8 1.6 6.1e-34 116.5 1.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 KII89372.1 - 0.047 13.3 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Barwin family COX17 PF05051.8 KII89375.1 - 3.8e-19 68.4 2.5 4.4e-19 68.2 1.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_L32p PF01783.18 KII89375.1 - 0.1 12.8 0.9 0.15 12.2 0.7 1.5 1 1 0 1 1 1 0 Ribosomal L32p protein family E1-E2_ATPase PF00122.15 KII89378.1 - 1.1e-60 204.5 1.8 2e-60 203.7 1.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KII89378.1 - 7.5e-30 104.9 0.0 3.8e-29 102.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KII89378.1 - 1.8e-20 73.2 18.9 1e-15 57.7 1.2 4.1 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KII89378.1 - 8.3e-20 70.5 0.0 1.8e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KII89378.1 - 3.1e-15 55.3 0.0 6.6e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KII89378.1 - 1.3e-14 54.7 0.0 3.5e-14 53.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KII89378.1 - 0.00015 21.4 0.4 0.028 13.9 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.1 KII89378.1 - 0.68 10.0 10.0 3.8 7.6 2.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF1691 PF07950.6 KII89379.1 - 7e-07 29.1 1.1 0.00031 20.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Peptidase_S10 PF00450.17 KII89383.1 - 2.1e-104 349.9 0.0 2.6e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KII89383.1 - 6.8e-06 26.1 0.3 6.5e-05 22.9 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Herpes_gE PF02480.11 KII89384.1 - 0.054 11.7 0.0 0.085 11.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EVI2A PF05399.6 KII89384.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) ATP-synt_8 PF00895.15 KII89384.1 - 0.085 13.0 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 Mucin PF01456.12 KII89384.1 - 0.12 12.1 3.3 0.33 10.7 2.3 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein HMG_box PF00505.14 KII89386.1 - 1.9e-10 40.8 5.7 5.9e-10 39.2 3.9 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII89386.1 - 5.9e-06 26.5 0.6 1.2e-05 25.6 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain Polysacc_lyase PF14099.1 KII89387.1 - 0.033 13.8 0.1 0.24 11.0 0.1 2.2 1 1 0 1 1 1 0 Polysaccharide lyase Pol_alpha_B_N PF08418.5 KII89387.1 - 1.2 8.6 11.4 1.7 8.1 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal OPT PF03169.10 KII89388.1 - 7.6e-198 658.8 64.0 8.8e-198 658.6 44.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4229 PF14012.1 KII89388.1 - 3.3 7.6 11.6 19 5.2 4.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Methyltransf_23 PF13489.1 KII89389.1 - 2.1e-19 69.8 0.0 3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII89389.1 - 4.5e-19 68.5 0.0 7.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII89389.1 - 1.6e-13 50.9 0.1 3.1e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII89389.1 - 2.2e-12 47.3 0.1 5.5e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII89389.1 - 2.5e-12 47.3 0.4 1.3e-11 45.0 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII89389.1 - 5.2e-11 42.8 0.2 1.6e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII89389.1 - 1.2e-09 38.2 1.0 2.4e-09 37.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII89389.1 - 1.2e-07 31.1 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KII89389.1 - 2.5e-06 26.9 0.0 3.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KII89389.1 - 5.5e-05 22.4 0.0 7.8e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KII89389.1 - 7.6e-05 22.7 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 KII89389.1 - 0.00013 20.7 0.0 0.00018 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 KII89389.1 - 0.0003 20.4 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KII89389.1 - 0.00051 19.2 0.0 0.0007 18.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KII89389.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KII89389.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pox_MCEL PF03291.11 KII89389.1 - 0.038 12.8 0.0 0.1 11.4 0.0 1.5 1 1 0 1 1 1 0 mRNA capping enzyme CmcI PF04989.7 KII89389.1 - 0.039 13.2 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase TPMT PF05724.6 KII89389.1 - 0.06 12.7 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) IMS PF00817.15 KII89390.1 - 6.5e-42 142.8 0.0 1.2e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KII89390.1 - 2.9e-15 56.3 0.0 6.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KII89390.1 - 1.4e-06 28.2 1.4 0.08 12.8 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KII89390.1 - 2.4e-06 27.2 0.0 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 KII89390.1 - 0.0002 21.1 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KII89390.1 - 0.00088 19.3 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.6 KII89390.1 - 0.03 14.1 0.0 0.094 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) VSP PF03302.8 KII89391.1 - 0.0081 14.8 159.2 0.014 14.0 16.0 6.9 1 1 4 5 5 5 4 Giardia variant-specific surface protein DUF4381 PF14316.1 KII89391.1 - 0.057 13.5 3.5 0.1 12.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PP2C PF00481.16 KII89392.1 - 8.4e-20 71.2 0.0 1.6e-17 63.7 0.0 2.8 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KII89392.1 - 5e-06 26.0 0.0 2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KII89392.1 - 0.0012 18.6 0.0 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Cyt_c_ox_IV PF12270.3 KII89393.1 - 0.063 13.0 7.9 1.8 8.3 3.5 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Sarcoglycan_2 PF05510.8 KII89393.1 - 0.12 10.6 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon LMBR1 PF04791.11 KII89394.1 - 0.055 12.0 0.0 0.055 12.0 0.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Glycos_transf_1 PF00534.15 KII89397.1 - 2.9e-25 88.6 0.0 2.1e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KII89397.1 - 9.3e-11 42.1 0.6 2.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KII89397.1 - 7.1e-07 29.1 0.4 1.7e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KII89397.1 - 2.1e-06 27.9 0.0 9.6e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KII89397.1 - 0.00047 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TNFR_c6 PF00020.13 KII89400.1 - 0.038 14.0 1.1 0.058 13.4 0.7 1.2 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region Fer4_2 PF12797.2 KII89400.1 - 1.2 9.2 4.4 1.1 9.3 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S binding domain DUF1014 PF06244.7 KII89402.1 - 7.6e-26 90.7 18.7 9.4e-25 87.1 13.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) U79_P34 PF03064.11 KII89402.1 - 4.9 6.6 10.9 7.1 6.0 7.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 KII89402.1 - 8.7 3.9 7.7 9.2 3.8 5.3 1.2 1 0 0 1 1 1 0 Ycf1 Calcipressin PF04847.7 KII89403.1 - 8e-34 116.8 0.0 8.7e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Calcipressin F-box-like PF12937.2 KII89404.1 - 1.4e-05 24.6 2.4 2.5e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 F-box-like LRR_2 PF07723.8 KII89404.1 - 0.05 14.1 0.3 0.31 11.5 0.2 2.5 1 0 0 1 1 1 0 Leucine Rich Repeat F-box PF00646.28 KII89404.1 - 0.11 12.1 6.1 0.51 10.0 2.1 3.3 2 1 0 2 2 2 0 F-box domain BTB PF00651.26 KII89405.1 - 8.2e-08 32.2 0.0 2.4e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain FA_desaturase PF00487.19 KII89407.1 - 1.9e-25 89.7 17.8 3.7e-25 88.8 12.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KII89407.1 - 0.021 14.8 0.1 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4282 PF14110.1 KII89407.1 - 0.034 14.3 0.3 0.034 14.3 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3374 PF11854.3 KII89407.1 - 0.14 10.3 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) AA_kinase PF00696.23 KII89408.1 - 5.3e-39 134.1 2.2 8.1e-39 133.5 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KII89408.1 - 1.7e-10 40.5 3.7 9.5e-06 25.2 0.2 2.8 3 0 0 3 3 3 2 PUA domain DOPA_dioxygen PF08883.6 KII89409.1 - 1.4e-25 89.3 0.1 1.7e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF4563 PF15124.1 KII89409.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4563) Pribosyltran_N PF13793.1 KII89410.1 - 1.8e-49 166.3 0.4 3.3e-48 162.2 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KII89410.1 - 6.2e-40 136.9 0.2 8.1e-36 123.4 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KII89410.1 - 1.3e-15 57.1 0.2 1.1e-13 51.0 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KII89410.1 - 8.9e-05 21.7 0.1 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KII89410.1 - 0.036 13.3 0.1 0.076 12.3 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase Per1 PF04080.8 KII89413.1 - 9.5e-92 307.2 6.6 1.2e-91 306.9 4.6 1.1 1 0 0 1 1 1 1 Per1-like Sed5p PF11416.3 KII89413.1 - 0.051 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Integral membrane protein Sed5p Hist_deacetyl PF00850.14 KII89414.1 - 3e-79 266.5 0.2 3.9e-79 266.1 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_transf_28 PF03033.15 KII89415.1 - 4.5e-23 81.5 0.0 1.4e-22 79.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.6 KII89415.1 - 0.00023 21.2 0.1 0.0009 19.3 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain UDPGT PF00201.13 KII89415.1 - 0.0017 17.0 0.6 0.0017 17.0 0.4 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KII89415.1 - 0.0032 17.1 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RNA_pol PF00940.14 KII89416.1 - 5.6e-05 21.7 0.0 5.9e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RNA_polI_A34 PF08208.6 KII89417.1 - 8.8e-17 61.4 2.6 8.8e-17 61.4 1.8 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Ada3 PF10198.4 KII89418.1 - 1.5e-23 82.9 0.0 1.5e-23 82.9 0.0 2.5 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Herpes_UL25 PF01499.11 KII89418.1 - 0.17 10.1 2.4 0.15 10.3 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus UL25 family FadA PF09403.5 KII89418.1 - 0.31 11.0 5.9 0.37 10.8 0.4 3.0 2 1 0 2 2 2 0 Adhesion protein FadA MgtE PF01769.11 KII89419.1 - 2.1e-24 86.3 21.7 2.5e-09 37.5 3.3 3.8 3 1 0 3 3 3 3 Divalent cation transporter ADH_zinc_N PF00107.21 KII89420.1 - 2.4e-11 43.3 0.1 6e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89420.1 - 1.3e-10 40.9 0.0 3e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII89420.1 - 0.00046 21.0 0.0 0.00078 20.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Phos_pyr_kin PF08543.7 KII89421.1 - 1.4e-81 273.2 0.0 1.7e-80 269.8 0.0 2.0 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KII89421.1 - 2.7e-42 144.8 0.0 4.2e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KII89421.1 - 0.00026 20.2 0.0 0.0039 16.3 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ADH_zinc_N PF00107.21 KII89422.1 - 8.3e-14 51.2 0.2 1.3e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89422.1 - 1.5e-11 44.0 0.0 3.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HhH-GPD PF00730.20 KII89423.1 - 1.9e-17 63.4 0.0 3.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KII89423.1 - 0.0057 16.2 0.0 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Mak10 PF04112.8 KII89424.1 - 1.8e-35 121.6 0.0 3.8e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.20 KII89425.1 - 4.7e-73 245.8 0.0 5.7e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) GMC_oxred_N PF00732.14 KII89426.1 - 2.6e-59 200.7 0.0 3.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII89426.1 - 1.4e-34 119.4 0.1 2.5e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KII89426.1 - 0.0015 17.5 0.9 0.0042 16.0 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII89426.1 - 0.0019 17.1 0.1 0.083 11.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KII89426.1 - 0.0061 16.5 0.2 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII89426.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KII89426.1 - 0.03 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 KII89427.1 - 6.9e-13 48.2 0.1 1.3e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89427.1 - 6.6e-11 41.9 0.0 1.8e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII89427.1 - 2.1e-05 25.4 0.1 3.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SUV3_C PF12513.3 KII89428.1 - 9e-14 50.6 0.0 2.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KII89428.1 - 4.4e-09 36.0 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MRP-S33 PF08293.6 KII89429.1 - 2.1e-24 85.3 1.6 2.6e-24 85.0 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF3984 PF13136.1 KII89431.1 - 0.45 9.6 6.3 0.76 8.9 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) TT_ORF1 PF02956.9 KII89431.1 - 8 4.7 9.2 11 4.2 6.4 1.2 1 0 0 1 1 1 0 TT viral orf 1 p450 PF00067.17 KII89432.1 - 7.2e-05 21.4 0.0 0.00021 19.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF2637 PF10935.3 KII89434.1 - 0.063 13.2 4.8 0.12 12.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) DUF2824 PF11039.3 KII89434.1 - 0.1 12.2 0.6 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) L27 PF02828.11 KII89436.1 - 0.028 14.0 0.7 0.15 11.7 0.1 2.3 2 0 0 2 2 2 0 L27 domain adh_short PF00106.20 KII89437.1 - 1.1e-23 83.9 1.3 4.6e-23 81.9 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII89437.1 - 8.6e-20 71.5 0.1 1.2e-19 71.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII89437.1 - 5.2e-07 29.5 0.1 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII89437.1 - 0.00031 20.2 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KII89437.1 - 0.0016 18.5 0.4 0.0032 17.5 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KII89437.1 - 0.0016 18.4 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KII89437.1 - 0.0036 16.4 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 KII89437.1 - 0.012 14.8 0.4 0.019 14.2 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family AdoHcyase_NAD PF00670.16 KII89437.1 - 0.012 15.4 0.3 0.028 14.2 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 KII89437.1 - 0.037 14.2 0.1 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KII89437.1 - 0.076 12.6 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KII89437.1 - 0.14 11.9 1.6 0.34 10.7 1.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IPK PF03770.11 KII89438.1 - 5.2e-42 143.7 0.0 6.8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Nucleoplasmin PF03066.10 KII89438.1 - 0.12 11.8 4.9 0.24 10.9 3.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin RhoGEF PF00621.15 KII89440.1 - 3.1e-44 150.9 2.2 5.5e-44 150.1 1.5 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 KII89440.1 - 1.9e-21 75.3 2.9 6.9e-11 41.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KII89440.1 - 5.2e-20 70.5 0.5 1.9e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 KII89440.1 - 1.1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 KII89440.1 - 3.5e-11 42.4 0.1 0.00016 21.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 KII89440.1 - 1.3e-09 37.2 0.5 3.2e-09 36.1 0.3 1.7 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 KII89440.1 - 2.8e-06 27.3 0.1 9.9e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KII89440.1 - 4.5e-05 22.4 0.1 0.073 12.4 0.0 3.0 2 0 0 2 2 2 2 EF hand PH PF00169.24 KII89440.1 - 7.4e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.1 KII89440.1 - 0.00085 19.0 0.3 2.5 8.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KII89440.1 - 0.0041 16.7 0.0 0.012 15.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair zf-MYND PF01753.13 KII89441.1 - 1.5e-11 43.9 9.8 1.5e-11 43.9 6.8 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KII89441.1 - 2.7 7.6 15.7 0.98 9.1 3.1 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-Mss51 PF13824.1 KII89441.1 - 8.3 6.3 8.1 10 6.0 2.9 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CDC73 PF05179.9 KII89442.1 - 2.9e-53 180.9 0.6 4.2e-53 180.4 0.4 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family MFS_1 PF07690.11 KII89443.1 - 4e-36 124.4 25.0 4e-36 124.4 17.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII89443.1 - 3.2e-19 68.8 3.4 3.2e-19 68.8 2.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KII89443.1 - 2.1e-05 22.9 0.3 3.2e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N PF00107.21 KII89444.1 - 6.8e-17 61.2 0.2 1.7e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89444.1 - 9.2e-11 41.4 0.1 2.8e-10 39.9 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RasGEF PF00617.14 KII89445.1 - 5.6e-55 185.9 0.0 9.4e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII89445.1 - 1.7e-20 73.0 0.1 4.4e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.21 KII89445.1 - 0.032 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 WW domain Pkinase PF00069.20 KII89447.1 - 2.3e-14 53.2 0.0 3.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89447.1 - 3.7e-06 26.2 0.0 7.4e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII89448.1 - 4.3e-13 49.0 0.0 1.4e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89448.1 - 0.00043 19.4 0.0 0.001 18.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 KII89448.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Lipase_3 PF01764.20 KII89449.1 - 8.2e-07 28.7 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KII89449.1 - 0.026 14.2 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KII89449.1 - 0.14 11.9 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KII89449.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein F-box-like PF12937.2 KII89450.1 - 9e-06 25.3 0.0 3.3e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KII89450.1 - 0.011 15.4 0.8 0.12 12.1 0.0 2.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 KII89450.1 - 0.044 13.4 0.5 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KII89450.1 - 0.085 12.9 0.0 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat ADH_zinc_N PF00107.21 KII89451.1 - 9.6e-15 54.2 0.9 7.5e-14 51.4 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89451.1 - 3.9e-09 36.2 0.0 7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII89452.1 - 1.4e-14 53.7 0.1 2.2e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89452.1 - 4.4e-09 36.0 0.0 7.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain OPA3 PF07047.7 KII89453.1 - 3.8e-33 114.0 0.1 7.3e-33 113.1 0.0 1.4 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Rootletin PF15035.1 KII89453.1 - 0.019 14.9 0.2 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lig_chan-Glu_bd PF10613.4 KII89453.1 - 0.038 13.9 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site Dor1 PF04124.7 KII89453.1 - 0.038 12.4 0.2 0.056 11.8 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family Mnd1 PF03962.10 KII89453.1 - 0.13 11.9 0.6 0.19 11.3 0.4 1.2 1 0 0 1 1 1 0 Mnd1 family Cellulase PF00150.13 KII89454.1 - 4.1e-15 55.7 1.9 3.1e-09 36.4 0.0 3.1 3 1 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KII89454.1 - 0.003 16.9 0.1 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 eIF2A PF08662.6 KII89455.1 - 1e-78 263.5 0.0 2.1e-77 259.2 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KII89455.1 - 0.0093 15.8 0.6 1.4 8.8 0.1 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat CDV3 PF15359.1 KII89455.1 - 0.015 15.3 1.9 0.015 15.3 1.3 2.4 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DPPIV_N PF00930.16 KII89455.1 - 0.15 10.6 0.0 19 3.6 0.0 2.7 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 KII89455.1 - 0.17 11.2 3.9 11 5.3 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Rb_C PF08934.5 KII89460.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Rb C-terminal domain Pinin_SDK_N PF04697.8 KII89460.1 - 0.047 13.7 0.2 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 pinin/SDK conserved region Rota_NS26 PF01525.11 KII89461.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Rotavirus NS26 DUF1143 PF06608.6 KII89462.1 - 0.029 14.3 1.5 4.4 7.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1143) Gram_pos_anchor PF00746.16 KII89463.1 - 8.7 6.2 13.0 17 5.3 0.1 4.3 4 0 0 4 4 4 0 Gram positive anchor Yip1 PF04893.12 KII89466.1 - 0.0009 18.7 2.5 0.0012 18.3 1.7 1.1 1 0 0 1 1 1 1 Yip1 domain DUF2976 PF11190.3 KII89466.1 - 4.9 6.7 7.2 11 5.6 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) MFS_1 PF07690.11 KII89467.1 - 3.9e-45 154.1 47.4 4e-44 150.7 32.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KII89467.1 - 2.2e-10 39.3 12.4 3.4e-10 38.7 8.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3020 PF11223.3 KII89469.1 - 1.2 9.5 11.4 3.7 8.0 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) Shugoshin_C PF07557.6 KII89472.1 - 8.2e-11 41.1 4.4 8.2e-11 41.1 3.0 3.8 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 KII89472.1 - 1.7e-05 24.4 1.8 3.4e-05 23.4 1.2 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TYA PF01021.14 KII89472.1 - 0.02 15.0 4.8 0.02 15.0 3.3 2.3 2 0 0 2 2 2 0 TYA transposon protein Cyclase PF04199.8 KII89473.1 - 2.2e-16 60.0 0.0 3.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pkinase PF00069.20 KII89474.1 - 3.6e-50 170.5 0.0 5.4e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89474.1 - 1.4e-24 86.6 0.0 2.7e-24 85.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KII89474.1 - 0.013 14.3 0.1 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KII89474.1 - 0.069 12.4 0.3 2.8 7.2 0.2 2.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.9 KII89474.1 - 0.071 12.1 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2414 PF10309.4 KII89480.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Asp_protease_2 PF13650.1 KII89481.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.1 KII89481.1 - 0.043 13.4 0.7 0.11 12.1 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Tet_JBP PF12851.2 KII89483.1 - 2.6e-06 26.8 0.0 5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Rubella_Capsid PF05750.6 KII89484.1 - 0.31 10.3 6.5 0.42 9.9 4.5 1.1 1 0 0 1 1 1 0 Rubella capsid protein Synthase_beta PF11421.3 KII89485.1 - 0.75 10.5 3.3 0.8 10.4 0.0 2.5 2 1 0 2 2 2 0 ATP synthase F1 beta subunit Transposase_21 PF02992.9 KII89487.1 - 1.2e-11 44.2 0.0 2.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KII89487.1 - 0.00011 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Cupin_8 PF13621.1 KII89489.1 - 0.0012 18.4 1.3 0.0082 15.6 0.1 2.3 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 KII89489.1 - 0.021 14.1 1.8 0.22 10.7 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein LRR_4 PF12799.2 KII89490.1 - 0.05 13.2 2.4 14 5.4 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KII89490.1 - 3.5 7.9 4.3 80 3.7 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.2 KII89491.1 - 0.0082 15.8 0.0 0.031 14.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like DUF566 PF04484.7 KII89498.1 - 0.25 10.8 1.8 0.28 10.6 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) WD40 PF00400.27 KII89499.1 - 1.4e-08 34.3 0.5 0.0012 18.5 0.0 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat LRR_6 PF13516.1 KII89501.1 - 0.024 14.6 1.0 12 6.3 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat UvrD_C_2 PF13538.1 KII89502.1 - 1.7e-05 24.8 0.0 4.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 KII89502.1 - 0.0058 14.4 0.0 0.0075 14.0 0.0 1.0 1 0 0 1 1 1 1 Helicase DUF3962 PF13111.1 KII89503.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) SOBP PF15279.1 KII89511.1 - 0.01 16.2 3.1 0.016 15.6 2.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein YL1 PF05764.8 KII89511.1 - 0.21 11.1 25.4 0.046 13.3 15.3 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Ycf1 PF05758.7 KII89511.1 - 0.22 9.2 2.2 0.21 9.2 1.5 1.1 1 0 0 1 1 1 0 Ycf1 BUD22 PF09073.5 KII89511.1 - 1.7 7.6 20.8 9.6 5.1 0.1 2.2 1 1 1 2 2 2 0 BUD22 RR_TM4-6 PF06459.7 KII89511.1 - 2.4 7.9 9.4 4.7 7.0 6.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EBV-NA3 PF05009.7 KII89511.1 - 5.2 6.2 6.1 2.1 7.5 2.6 1.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) LRR_6 PF13516.1 KII89521.1 - 5.2e-09 35.2 8.3 0.19 11.8 0.0 7.9 10 0 0 10 10 10 3 Leucine Rich repeat LRR_8 PF13855.1 KII89521.1 - 0.00053 19.6 5.5 9.7 6.0 0.3 5.1 5 1 0 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 KII89521.1 - 0.0093 16.0 11.1 15 6.3 0.0 7.7 11 0 0 11 11 11 1 Leucine rich repeat LRR_1 PF00560.28 KII89521.1 - 0.035 14.1 4.7 49 4.5 0.0 5.5 7 0 0 7 7 7 0 Leucine Rich Repeat TIMELESS_C PF05029.8 KII89521.1 - 0.038 12.9 17.7 0.056 12.3 12.3 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region CDC27 PF09507.5 KII89521.1 - 0.17 11.1 17.9 0.26 10.4 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-piccolo PF05715.8 KII89521.1 - 1.9 8.5 11.6 3.5 7.6 1.3 3.2 3 1 0 3 3 3 0 Piccolo Zn-finger TFIIF_alpha PF05793.7 KII89521.1 - 2.7 6.2 21.3 3.8 5.7 14.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.20 KII89525.1 - 8.4e-41 139.8 0.0 1.1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89525.1 - 3.4e-17 62.3 0.0 2.7e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII89525.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII89525.1 - 0.26 10.0 0.1 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Microtub_assoc PF07989.6 KII89526.1 - 8.4e-21 73.5 10.6 8.4e-21 73.5 7.4 8.7 9 3 1 11 11 11 2 Microtubule associated Mto2_bdg PF12808.2 KII89526.1 - 0.0035 17.4 10.2 0.0035 17.4 7.1 11.2 11 2 1 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF869 PF05911.6 KII89526.1 - 1 7.5 102.3 0.022 12.9 30.9 4.4 1 1 3 4 4 4 0 Plant protein of unknown function (DUF869) Filament PF00038.16 KII89526.1 - 5.2 6.4 142.6 0.059 12.8 33.2 7.8 3 3 3 7 7 7 0 Intermediate filament protein Reo_sigmaC PF04582.7 KII89526.1 - 6.4 5.8 40.4 1.8 7.6 1.0 7.2 3 2 5 8 8 8 0 Reovirus sigma C capsid protein MFS_1 PF07690.11 KII89528.1 - 1.1e-39 136.1 32.7 1.1e-39 136.1 22.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII89528.1 - 1.3e-09 37.2 8.0 1.3e-09 37.2 5.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter C2 PF00168.25 KII89529.1 - 8.6e-15 54.3 0.0 1.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pollen_allerg_1 PF01357.16 KII89529.1 - 0.063 13.0 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Pollen allergen DPBB_1 PF03330.13 KII89530.1 - 8.8e-08 32.0 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII89530.1 - 0.0087 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Barwin family Pectinesterase PF01095.14 KII89533.1 - 1.8e-43 148.2 0.9 2.3e-43 147.8 0.6 1.0 1 0 0 1 1 1 1 Pectinesterase ADH_zinc_N PF00107.21 KII89534.1 - 1.4e-14 53.7 1.0 2.6e-14 52.8 0.1 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89534.1 - 5.4e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII89535.1 - 2.6e-14 52.8 0.2 4.8e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89535.1 - 1.3e-09 37.7 0.0 3.4e-09 36.4 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_3_C PF01915.17 KII89537.1 - 5.1e-72 242.0 0.0 2.6e-71 239.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KII89537.1 - 3.6e-67 226.4 0.0 5.6e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KII89537.1 - 1e-22 79.8 0.5 2.5e-22 78.5 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KII89537.1 - 5.4e-11 42.3 0.0 9.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain ADH_N PF08240.7 KII89538.1 - 4.7e-29 100.3 0.9 8.4e-29 99.5 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII89538.1 - 2.7e-26 91.6 1.3 4.7e-26 90.8 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII89538.1 - 0.012 16.5 0.3 0.028 15.3 0.2 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Fer4_10 PF13237.1 KII89538.1 - 0.02 14.7 0.3 0.039 13.7 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain OppC_N PF12911.2 KII89540.1 - 0.0051 16.1 0.1 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Rifin_STEVOR PF02009.11 KII89540.1 - 0.27 10.8 0.1 0.4 10.2 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF605 PF04652.11 KII89540.1 - 0.57 9.5 17.9 1 8.7 12.4 1.5 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KII89540.1 - 4.8 6.9 9.2 7.4 6.3 6.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DBR1 PF05011.8 KII89542.1 - 3.8e-34 117.6 0.0 6e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KII89542.1 - 3.6e-10 39.5 1.6 5.3e-10 39.0 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII89542.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KII89542.1 - 0.0037 16.4 0.0 0.0083 15.2 0.0 1.6 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily FTCD_C PF04961.7 KII89546.1 - 3 7.2 0.0 3 7.2 0.0 3.3 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase ERbeta_N PF12497.3 KII89549.1 - 0.15 11.9 0.5 0.23 11.3 0.4 1.3 1 0 0 1 1 1 0 Estrogen receptor beta Cyclin PF08613.6 KII89552.1 - 3.1e-27 95.8 0.0 3.1e-27 95.8 0.0 2.4 2 1 1 3 3 3 1 Cyclin DUF4451 PF14616.1 KII89556.1 - 2.6e-08 33.6 6.3 0.3 10.8 0.1 4.2 3 1 0 4 4 4 3 Domain of unknown function (DUF4451) zf-dskA_traR PF01258.12 KII89556.1 - 0.074 12.7 3.0 5.1 6.9 0.1 3.4 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Ecl1 PF12855.2 KII89556.1 - 0.87 8.9 5.9 0.34 10.2 0.2 2.5 2 0 0 2 2 2 0 Life-span regulatory factor DUF2039 PF10217.4 KII89556.1 - 1 9.4 8.6 2.4 8.2 0.6 3.8 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2039) PHD PF00628.24 KII89556.1 - 3.2 7.5 6.4 29 4.4 0.1 3.9 4 0 0 4 4 4 0 PHD-finger zf-C2H2_4 PF13894.1 KII89556.1 - 5 7.6 10.2 29 5.3 0.2 3.5 2 1 0 2 2 2 0 C2H2-type zinc finger Shisa PF13908.1 KII89560.1 - 0.029 14.5 0.1 0.029 14.5 0.1 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 KII89560.1 - 9.5 5.7 10.5 0.13 11.7 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Brix PF04427.13 KII89561.1 - 8.1e-29 100.6 0.0 1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.2 KII89563.1 - 4.9e-11 42.1 0.1 1.1e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like DnaG_DnaB_bind PF08278.6 KII89563.1 - 0.13 12.4 2.8 4.8 7.4 0.1 2.6 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding HNH_2 PF13391.1 KII89564.1 - 0.03 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease HNH_2 PF13391.1 KII89565.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 KII89566.1 - 1.3e-40 139.2 0.1 1.8e-22 79.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII89566.1 - 4.4e-14 52.1 0.3 4.2e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KII89566.1 - 0.035 12.9 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HOOK PF05622.7 KII89567.1 - 0.0032 15.3 3.0 0.0044 14.9 2.1 1.1 1 0 0 1 1 1 1 HOOK protein Yae1_N PF09811.4 KII89567.1 - 0.0062 16.0 1.6 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Macoilin PF09726.4 KII89567.1 - 0.36 9.0 2.6 0.51 8.5 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 KII89567.1 - 1.4 8.7 4.4 2.9 7.7 0.7 2.0 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4218 PF13960.1 KII89568.1 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) UBN2_2 PF14227.1 KII89569.1 - 9.4e-11 41.3 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII89569.1 - 1e-07 31.7 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII89569.1 - 0.024 14.5 5.0 0.039 13.8 3.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KII89569.1 - 0.5 9.8 4.4 1 8.9 3.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.12 KII89572.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Erythro-docking PF09277.6 KII89572.1 - 0.11 12.2 2.0 0.24 11.0 1.4 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking Na_H_antiporter PF03553.9 KII89577.1 - 0.16 10.9 2.7 0.19 10.7 1.9 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter family HisKA_3 PF07730.8 KII89580.1 - 0.00033 20.9 6.8 0.11 12.8 0.8 3.3 3 0 0 3 3 3 2 Histidine kinase Nbl1_Borealin_N PF10444.4 KII89580.1 - 0.013 14.8 1.2 0.027 13.8 0.8 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Zn_clus PF00172.13 KII89580.1 - 0.71 9.8 9.8 4 7.4 3.2 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Utp13 PF08625.6 KII89582.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain OAD_gamma PF04277.8 KII89583.1 - 0.55 10.6 2.5 0.34 11.3 0.2 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Tet_JBP PF12851.2 KII89585.1 - 2.4e-13 49.7 0.0 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF592 PF04574.8 KII89586.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) BacteriocIIc_cy PF12173.3 KII89587.1 - 0.0086 16.0 3.7 3.5 7.7 0.0 3.3 1 1 2 3 3 3 2 Bacteriocin class IIc cyclic gassericin A-like Myb_DNA-binding PF00249.26 KII89588.1 - 0.66 10.0 2.7 17 5.5 0.0 2.8 3 1 0 3 3 3 0 Myb-like DNA-binding domain Dispanin PF04505.7 KII89594.1 - 0.09 12.3 1.2 0.17 11.4 0.3 1.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DUF3752 PF12572.3 KII89600.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3752) DASH_Dad2 PF08654.5 KII89600.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad2 P34-Arc PF04045.9 KII89605.1 - 3.9e-105 350.4 1.3 4.7e-105 350.2 0.9 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RRM_1 PF00076.17 KII89606.1 - 4.1e-16 58.3 0.1 8.6e-16 57.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII89606.1 - 5e-11 42.4 0.0 9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII89606.1 - 6.2e-05 22.7 0.0 0.00037 20.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 KII89607.1 - 5.5e-45 153.3 0.0 6.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 KII89608.1 - 4.5e-46 156.2 0.0 5.1e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII89608.1 - 3.9e-19 69.2 0.0 6.9e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII89608.1 - 2e-05 23.9 0.0 2.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII89608.1 - 0.00029 20.3 0.0 0.0029 17.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII89608.1 - 0.0077 16.1 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KII89608.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII89608.1 - 0.029 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KII89608.1 - 0.03 14.3 0.1 0.056 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Kdo_hydroxy PF11004.3 KII89608.1 - 0.042 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase ImcF-related_N PF14331.1 KII89608.1 - 0.045 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain FtsZ_C PF12327.3 KII89608.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DEAD PF00270.24 KII89609.1 - 2.6e-49 166.9 0.0 1e-47 161.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII89609.1 - 3.1e-28 97.4 0.0 7.4e-28 96.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII89609.1 - 1.4e-06 28.2 0.0 4.9e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KII89609.1 - 0.003 16.0 0.0 0.015 13.7 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KII89609.1 - 0.0056 16.6 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_30 PF13604.1 KII89609.1 - 0.026 14.0 0.0 0.18 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain Ndufs5 PF10200.4 KII89609.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Alba PF01918.16 KII89610.1 - 3.2e-05 23.4 0.1 0.39 10.3 0.0 3.0 3 0 0 3 3 3 2 Alba PHD PF00628.24 KII89611.1 - 3.8e-07 29.6 11.0 6.7e-07 28.9 7.6 1.4 1 0 0 1 1 1 1 PHD-finger APC10 PF03256.11 KII89612.1 - 1.2e-44 152.2 0.0 1.3e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 KII89612.1 - 2.7e-05 23.9 0.0 5.6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 F5/8 type C domain ThiF PF00899.16 KII89613.1 - 1.1e-43 148.3 0.0 1.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KII89613.1 - 1.4e-28 98.2 0.1 3.3e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KII89613.1 - 2.3e-11 44.0 0.0 4.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KII89613.1 - 0.0003 20.8 0.1 0.0022 18.0 0.1 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KII89613.1 - 0.15 11.3 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UBX PF00789.15 KII89614.1 - 5.4e-11 42.3 0.2 8.7e-11 41.7 0.2 1.3 1 0 0 1 1 1 1 UBX domain PITH PF06201.8 KII89615.1 - 3.2e-38 130.8 0.0 4.1e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Med25_VWA PF11265.3 KII89616.1 - 0.0091 15.0 0.0 0.022 13.8 0.0 1.7 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A TMEM247 PF15444.1 KII89616.1 - 2.3 7.9 4.7 4.6 6.9 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 SH3_9 PF14604.1 KII89619.1 - 7.3e-15 54.2 0.1 1.2e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII89619.1 - 1.5e-12 46.8 0.0 2.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII89619.1 - 7.4e-12 44.4 0.0 1.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain TSP_1 PF00090.14 KII89620.1 - 0.096 12.8 0.9 0.096 12.8 0.6 1.9 2 0 0 2 2 2 0 Thrombospondin type 1 domain YchF-GTPase_C PF06071.8 KII89623.1 - 9.6e-36 121.4 0.1 2.5e-35 120.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KII89623.1 - 5.9e-15 55.2 0.0 1.6e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII89623.1 - 9.8e-06 24.9 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 KII89623.1 - 0.0011 18.3 0.2 0.0068 15.7 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 AAA_17 PF13207.1 KII89623.1 - 0.013 16.2 0.1 0.046 14.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain PQQ PF01011.16 KII89624.1 - 0.002 17.5 0.3 1.2 8.7 0.1 2.4 2 0 0 2 2 2 2 PQQ enzyme repeat LPAM_1 PF08139.7 KII89624.1 - 0.47 10.7 2.8 1.1 9.5 2.0 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site F-box-like PF12937.2 KII89625.1 - 4.2e-07 29.5 0.0 1.9e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 F-box-like SH3_9 PF14604.1 KII89626.1 - 5.4e-10 38.7 0.1 8.3e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII89626.1 - 3.3e-07 29.5 0.0 4.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII89626.1 - 0.00087 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain NUDIX PF00293.23 KII89627.1 - 1.7e-15 56.8 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1192 PF06698.6 KII89629.1 - 0.013 15.3 0.5 0.013 15.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MARVEL PF01284.18 KII89630.1 - 2.4e-09 37.1 6.8 3.6e-09 36.5 4.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4013 PF13197.1 KII89630.1 - 0.11 11.8 8.8 0.2 10.9 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF202 PF02656.10 KII89630.1 - 0.25 11.6 1.9 0.77 10.0 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Voldacs PF03517.8 KII89631.1 - 4.4e-26 91.3 0.0 6.1e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling TauD PF02668.11 KII89632.1 - 2e-37 129.2 0.1 4.1e-37 128.2 0.0 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KII89632.1 - 2.2e-07 31.2 0.0 4.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) LRR_8 PF13855.1 KII89633.1 - 0.0054 16.4 0.8 0.72 9.6 0.0 3.8 3 1 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.2 KII89634.1 - 2e-07 30.6 0.1 4.8e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 KII89636.1 - 1.7e-48 165.1 38.2 5.1e-31 107.6 11.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII89636.1 - 2.1 6.6 34.4 3.2 6.0 2.1 3.6 2 2 0 2 2 2 0 MFS/sugar transport protein Aconitase PF00330.15 KII89637.1 - 2.3e-71 240.6 0.3 1.5e-43 148.9 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KII89637.1 - 1.1e-19 70.8 0.0 2.1e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Telomere_Sde2 PF13019.1 KII89639.1 - 3.2e-53 179.7 0.0 3.9e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing IlvN PF07991.7 KII89640.1 - 7e-46 155.6 0.0 1.2e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KII89640.1 - 6.8e-41 139.5 0.0 1e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KII89640.1 - 0.16 12.4 0.7 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent F-box-like PF12937.2 KII89642.1 - 3.6e-07 29.7 0.4 9.4e-07 28.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII89642.1 - 0.29 10.8 1.1 5.7 6.6 0.0 3.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Syndecan PF01034.15 KII89643.1 - 0.056 13.1 0.0 0.58 9.8 0.1 2.1 2 0 0 2 2 2 0 Syndecan domain Gly-zipper_OmpA PF13436.1 KII89643.1 - 7.8 6.1 13.3 16 5.1 9.3 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Glycophorin_A PF01102.13 KII89644.1 - 0.0062 16.2 6.7 0.0062 16.2 4.6 3.1 1 1 1 2 2 2 1 Glycophorin A P12 PF12669.2 KII89644.1 - 0.026 14.7 0.2 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Herpes_UL32 PF06070.6 KII89644.1 - 1.6 7.1 9.6 1.9 6.8 6.7 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Podoplanin PF05808.6 KII89644.1 - 4.9 6.6 14.0 27 4.2 9.7 2.0 1 1 0 1 1 1 0 Podoplanin Phage_Coat_B PF05356.6 KII89644.1 - 9.2 6.0 7.4 0.65 9.7 0.8 2.2 2 0 0 2 2 2 0 Phage Coat protein B Aminotran_3 PF00202.16 KII89646.1 - 2.6e-41 141.6 0.0 1.5e-40 139.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 KII89646.1 - 7.8e-28 97.4 0.0 1.3e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF1045 PF06299.7 KII89647.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) PI3Ka PF00613.15 KII89648.1 - 4.8e-54 182.3 0.1 7.4e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KII89648.1 - 1.5e-43 148.9 0.0 4.6e-42 144.1 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KII89648.1 - 1.6e-40 138.2 0.0 2.6e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 KII89648.1 - 0.00077 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Amidohydro_1 PF01979.15 KII89649.1 - 4.8e-54 184.2 5.8 1.9e-53 182.2 3.4 2.0 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 KII89649.1 - 6.6e-54 181.1 1.4 1.5e-53 180.0 1.0 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KII89649.1 - 7.3e-42 141.2 0.2 2.3e-41 139.6 0.1 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KII89649.1 - 1.1e-39 134.3 0.3 3e-39 133.0 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KII89649.1 - 3.3e-06 26.8 1.4 9.8e-06 25.3 1.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KII89649.1 - 0.0085 15.3 4.8 0.13 11.4 1.1 2.8 1 1 1 2 2 2 2 Amidohydrolase family zf-C2H2 PF00096.21 KII89651.1 - 6.3e-05 23.0 0.6 6.3e-05 23.0 0.4 3.0 2 1 1 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.2 KII89651.1 - 0.00019 21.5 0.1 0.37 11.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KII89651.1 - 0.0004 20.5 5.3 0.0023 18.1 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII89651.1 - 0.04 14.0 0.1 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KII89651.1 - 3.2 8.2 5.9 1.2 9.6 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger double domain FtsJ PF01728.14 KII89652.1 - 1.2e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KII89652.1 - 0.0047 17.5 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HgmA PF04209.8 KII89653.1 - 4.1e-157 522.9 0.0 4.7e-157 522.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Transketolase_N PF00456.16 KII89654.1 - 5.2e-19 68.2 2.5 4.5e-18 65.1 1.7 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KII89654.1 - 8e-08 32.2 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KII89654.1 - 1.1e-05 24.9 0.3 2.7e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KII89654.1 - 0.00049 18.9 0.0 0.0009 18.0 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KII89654.1 - 0.0026 17.3 0.2 0.012 15.1 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4112 PF13430.1 KII89656.1 - 2.3e-30 104.6 0.1 3e-30 104.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HA2 PF04408.18 KII89659.1 - 4.9e-28 97.1 0.0 4.4e-27 94.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KII89659.1 - 2.1e-23 82.3 0.0 1.6e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KII89659.1 - 4.2e-13 48.9 0.0 9.3e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII89659.1 - 0.0035 16.8 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII89660.1 - 0.0021 18.2 0.1 0.0021 18.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KII89660.1 - 0.0036 17.7 0.1 0.0038 17.7 0.0 1.3 1 1 0 1 1 1 1 Miro-like protein SRP54 PF00448.17 KII89660.1 - 0.0078 15.6 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 KII89660.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 KII89660.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KII89660.1 - 0.014 15.0 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain PrcB_C PF14343.1 KII89660.1 - 0.016 14.9 0.1 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 PrcB C-terminal ABC_tran PF00005.22 KII89660.1 - 0.017 15.3 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KII89660.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KII89660.1 - 0.024 13.7 0.7 0.37 9.8 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin MobB PF03205.9 KII89660.1 - 0.032 13.9 0.2 0.051 13.2 0.1 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KII89660.1 - 0.056 13.1 0.4 0.097 12.4 0.3 1.5 1 1 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KII89660.1 - 0.061 12.8 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KII89660.1 - 0.074 12.4 0.1 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KII89660.1 - 0.09 12.7 0.0 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.24 KII89660.1 - 0.09 12.2 0.1 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.17 KII89660.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 KII89660.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KII89660.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KII89660.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain QH-AmDH_gamma PF08992.6 KII89662.1 - 0.096 12.4 1.3 0.5 10.1 0.9 2.1 1 1 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Nt_Gln_amidase PF09764.4 KII89662.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal glutamine amidase CHORD PF04968.7 KII89662.1 - 2 8.7 10.6 0.099 12.9 1.1 2.5 2 1 0 2 2 2 0 CHORD CHORD PF04968.7 KII89663.1 - 0.06 13.5 4.1 0.24 11.6 0.4 2.4 2 0 0 2 2 2 0 CHORD Microvir_J PF04726.8 KII89665.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Microvirus J protein Methyltransf_2 PF00891.13 KII89666.1 - 1.5e-33 115.9 0.0 3e-33 115.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII89666.1 - 0.0062 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KII89666.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_2 PF00891.13 KII89667.1 - 3.6e-30 104.9 0.0 5.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KII89667.1 - 0.00052 19.7 0.1 0.0017 18.1 0.1 2.0 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_18 PF12847.2 KII89667.1 - 0.033 14.7 0.1 0.091 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KII89667.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MarR PF01047.17 KII89667.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family MTS PF05175.9 KII89667.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ricin_B_lectin PF00652.17 KII89668.1 - 5.8e-19 68.3 0.4 3.2e-05 23.9 0.0 4.2 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain Med13_N PF11597.3 KII89668.1 - 0.41 9.2 4.9 0.61 8.7 3.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Profilin PF00235.14 KII89669.1 - 1.1e-05 25.5 0.0 1.6e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Profilin Tubulin PF00091.20 KII89672.1 - 2e-65 220.6 0.0 3e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KII89672.1 - 7e-40 135.9 0.0 1.1e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KII89672.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KII89672.1 - 0.0036 16.7 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Methyltransf_2 PF00891.13 KII89673.1 - 1.9e-34 118.9 0.0 4.6e-34 117.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KII89673.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KII89673.1 - 0.01 15.6 0.1 0.035 13.9 0.0 2.0 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_18 PF12847.2 KII89673.1 - 0.013 16.0 0.0 0.037 14.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 KII89673.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.14 KII89673.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cyanate_lyase PF02560.9 KII89675.1 - 1.2e-34 117.6 0.0 1.8e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 KII89675.1 - 0.0059 16.4 0.1 0.0088 15.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.7 KII89675.1 - 0.026 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.1 KII89675.1 - 0.026 14.7 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.2 KII89675.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4113 PF13438.1 KII89675.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4113) Complex1_LYR PF05347.10 KII89676.1 - 1.5e-11 43.9 0.0 2.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII89676.1 - 1.7e-09 37.7 0.0 3.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KII89676.1 - 1e-06 29.1 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF4604 PF15377.1 KII89677.1 - 2.1e-26 93.0 11.5 2.8e-26 92.5 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) YL1 PF05764.8 KII89677.1 - 0.57 9.7 8.1 1.1 8.7 5.5 1.6 1 1 0 1 1 1 0 YL1 nuclear protein TATR PF03430.8 KII89677.1 - 0.86 8.1 2.8 0.96 8.0 1.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Med8 PF10232.4 KII89678.1 - 6.3e-05 22.5 0.1 8.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 QRPTase_C PF01729.14 KII89678.1 - 0.054 13.0 0.4 0.1 12.1 0.2 1.4 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Glypican PF01153.14 KII89678.1 - 0.15 10.6 0.9 0.17 10.4 0.6 1.1 1 0 0 1 1 1 0 Glypican Abhydrolase_6 PF12697.2 KII89681.1 - 6.4e-25 88.3 0.0 8.5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII89681.1 - 3.5e-15 56.1 0.0 7.5e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII89681.1 - 2.8e-13 49.8 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KII89681.1 - 2.2e-08 33.9 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KII89681.1 - 8.2e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 KII89681.1 - 9.7e-06 25.9 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_2 PF01674.13 KII89681.1 - 0.00084 18.7 0.0 0.0063 15.8 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 2) DUF3444 PF11926.3 KII89681.1 - 0.0037 16.4 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3444) DUF915 PF06028.6 KII89681.1 - 0.012 14.7 0.1 2.4 7.1 0.0 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KII89681.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 KII89681.1 - 0.076 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 KII89681.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2048 PF09752.4 KII89681.1 - 0.12 11.2 0.0 0.63 8.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Steroid_dh PF02544.11 KII89682.1 - 6.4e-39 133.1 0.3 9.8e-39 132.5 0.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.5 KII89682.1 - 0.0096 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PEMT PF04191.8 KII89682.1 - 0.046 13.8 0.1 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase DUF1295 PF06966.7 KII89682.1 - 0.054 12.7 0.2 0.074 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) IncFII_repA PF02387.10 KII89683.1 - 0.014 14.5 0.2 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 IncFII RepA protein family HAUS5 PF14817.1 KII89683.1 - 0.02 13.4 1.9 0.03 12.8 1.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Arv1 PF04161.8 KII89684.1 - 3.6e-29 102.1 0.0 6e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Arv1-like family ATPase_gene1 PF09527.5 KII89684.1 - 2.3 8.0 5.8 0.79 9.5 1.4 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) COesterase PF00135.23 KII89685.1 - 1.2e-89 301.4 0.1 2e-89 300.7 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII89685.1 - 3.7e-09 36.4 0.6 2e-08 34.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII89685.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF420 PF04238.7 KII89686.1 - 0.027 14.4 1.4 0.055 13.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF420) DUF3329 PF11808.3 KII89686.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3329) zf-RING_5 PF14634.1 KII89687.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 zinc-RING finger domain TMEM151 PF14857.1 KII89688.1 - 0.074 11.6 0.0 0.091 11.3 0.0 1.1 1 0 0 1 1 1 0 TMEM151 family DUF410 PF04190.8 KII89689.1 - 2.6e-33 115.6 0.0 3.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HSBP1 PF06825.7 KII89690.1 - 3.1e-17 61.8 1.5 4.4e-17 61.3 1.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.7 KII89690.1 - 0.015 15.0 0.4 0.02 14.6 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 KII89690.1 - 0.02 14.2 0.7 0.31 10.4 0.3 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Flagellin_C PF00700.16 KII89690.1 - 0.037 14.1 0.2 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF4164 PF13747.1 KII89690.1 - 0.059 13.5 0.2 0.078 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 KII89690.1 - 0.14 12.3 0.7 0.3 11.3 0.5 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF935 PF06074.7 KII89690.1 - 0.15 10.7 0.3 0.16 10.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Ank PF00023.25 KII89691.1 - 1.9e-19 68.4 0.2 1.8e-06 27.4 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KII89691.1 - 1.4e-17 63.7 0.1 2.3e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KII89691.1 - 5.2e-16 57.1 0.1 1.5e-05 24.7 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KII89691.1 - 2.5e-13 49.7 0.1 6.3e-05 23.0 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KII89691.1 - 9.5e-13 48.2 0.1 1.6e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KII89692.1 - 4.9e-18 65.1 0.0 4.7e-12 46.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KII89692.1 - 5e-18 63.9 0.3 1.7e-12 46.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KII89692.1 - 1.9e-17 62.9 0.1 2.3e-11 43.5 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KII89692.1 - 2.1e-15 56.8 0.0 2.3e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KII89692.1 - 6.5e-11 41.3 0.0 3.5e-07 29.8 0.0 2.3 3 0 0 3 3 3 2 Ankyrin repeat Tfb2 PF03849.9 KII89693.1 - 1.6e-129 431.6 0.0 1.9e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KII89693.1 - 0.00039 20.1 0.0 0.00091 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gti1_Pac2 PF09729.4 KII89695.1 - 2.3e-47 160.9 1.4 2.5e-46 157.6 1.0 1.9 1 1 0 1 1 1 1 Gti1/Pac2 family Terpene_synth_C PF03936.11 KII89698.1 - 4.5e-17 62.1 0.0 6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.1 KII89698.1 - 0.061 13.1 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal zf-HC5HC2H_2 PF13832.1 KII89699.1 - 0.055 13.4 0.3 0.079 12.9 0.2 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KII89699.1 - 0.068 13.3 0.3 0.094 12.8 0.2 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF829 PF05705.9 KII89700.1 - 5.5e-38 131.0 0.0 1.8e-37 129.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) FtsJ PF01728.14 KII89701.1 - 0.002 18.1 0.0 0.017 15.0 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase AFOR_C PF01314.13 KII89701.1 - 0.057 12.1 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Cupin_1 PF00190.17 KII89702.1 - 2e-31 108.3 0.0 4.4e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KII89702.1 - 3e-30 103.5 0.2 9.4e-15 53.8 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KII89702.1 - 1.4e-11 43.5 0.0 5.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KII89702.1 - 2.4e-08 33.7 0.1 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.9 KII89702.1 - 0.00014 21.8 0.0 0.0036 17.2 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family 3-HAO PF06052.7 KII89702.1 - 0.00014 21.2 0.0 0.0018 17.6 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase MannoseP_isomer PF01050.13 KII89702.1 - 0.00019 21.1 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.7 KII89702.1 - 0.00026 20.3 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.1 KII89702.1 - 0.0012 18.3 0.0 0.91 8.9 0.0 2.5 2 1 0 2 2 2 2 Cupin-like domain FdtA PF05523.6 KII89702.1 - 0.0017 17.8 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 WxcM-like, C-terminal Ectoine_synth PF06339.7 KII89702.1 - 0.0068 16.3 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 1 Ectoine synthase Cupin_6 PF12852.2 KII89702.1 - 0.011 15.4 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Cupin GPI PF06560.6 KII89702.1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Pirin_C PF05726.8 KII89702.1 - 0.08 13.0 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Pirin C-terminal cupin domain 2OG-FeII_Oxy_5 PF13759.1 KII89702.1 - 0.082 13.1 0.2 16 5.8 0.0 3.3 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase RRM_1 PF00076.17 KII89703.1 - 1e-22 79.5 0.0 1.2e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII89703.1 - 2.4e-18 65.8 0.0 2.9e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII89703.1 - 3e-13 49.3 0.0 3.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 KII89703.1 - 7.2e-06 26.3 44.6 7.2e-06 26.3 30.9 2.1 2 0 0 2 2 2 1 Glycine rich protein family DcpS_C PF11969.3 KII89706.1 - 2.7e-24 85.6 2.5 3.2e-24 85.3 1.7 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KII89706.1 - 7e-08 32.9 8.0 2.7e-07 31.0 5.5 1.8 1 1 0 1 1 1 1 HIT domain CDH PF02611.10 KII89706.1 - 0.0068 15.6 0.0 0.0089 15.2 0.0 1.1 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Phage_gp49_66 PF13876.1 KII89706.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family UCH PF00443.24 KII89707.1 - 6.1e-60 202.6 0.1 8.9e-60 202.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII89707.1 - 9e-29 100.8 0.0 1.4e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KII89707.1 - 3.8e-14 52.5 7.8 3.8e-14 52.5 5.4 2.3 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Thg1C PF14413.1 KII89709.1 - 1.1e-47 160.6 0.1 1.8e-47 160.0 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KII89709.1 - 2.5e-43 146.9 0.1 3.9e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase SbmA_BacA PF05992.7 KII89709.1 - 0.037 13.2 1.0 0.09 11.9 0.1 1.8 2 0 0 2 2 2 0 SbmA/BacA-like family Fork_head PF00250.13 KII89710.1 - 1.9e-26 91.9 0.0 2.1e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Fork head domain DUF4047 PF13256.1 KII89710.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Abhydrolase_6 PF12697.2 KII89711.1 - 9.6e-22 77.9 0.4 1.4e-21 77.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII89711.1 - 4.8e-20 71.7 0.1 4.6e-19 68.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KII89711.1 - 3.5e-11 43.0 0.0 1.2e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KII89711.1 - 1.9e-08 33.8 0.0 8.9e-05 21.8 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KII89711.1 - 6.4e-08 32.3 0.0 9.7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KII89711.1 - 7.4e-08 31.9 0.0 6.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KII89711.1 - 7.3e-05 22.4 0.0 0.00026 20.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 KII89711.1 - 8.1e-05 21.2 0.1 0.08 11.4 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.5 KII89711.1 - 0.0044 16.9 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.6 KII89711.1 - 0.045 13.4 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.7 KII89711.1 - 0.068 11.7 0.0 0.091 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_2 PF02230.11 KII89711.1 - 0.08 12.3 0.0 12 5.2 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 KII89711.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) zf-C2H2_4 PF13894.1 KII89712.1 - 2.7e-08 33.5 6.3 0.002 18.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII89712.1 - 1.6e-07 31.2 6.8 0.0005 20.2 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII89712.1 - 0.045 14.0 6.3 0.1 12.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KII89712.1 - 0.39 10.9 4.8 4.1 7.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KII89712.1 - 2.1 8.7 5.9 14 6.1 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF629 PF04780.7 KII89712.1 - 5.1 5.4 5.4 2.4 6.5 1.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 KII89713.1 - 6.5e-05 22.9 6.7 0.084 13.2 2.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII89713.1 - 0.0029 17.8 0.6 0.0029 17.8 0.4 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KII89713.1 - 0.013 15.7 8.0 1 9.8 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pyocin_S PF06958.7 KII89713.1 - 0.076 13.3 0.3 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 S-type Pyocin Coq4 PF05019.8 KII89714.1 - 1.4e-92 308.5 0.0 1.7e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 zf-C2H2_4 PF13894.1 KII89715.1 - 0.0061 16.8 3.5 1.7 9.1 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger DUF605 PF04652.11 KII89715.1 - 0.9 8.8 9.8 1.2 8.4 6.8 1.2 1 0 0 1 1 1 0 Vta1 like Fer4_11 PF13247.1 KII89716.1 - 0.51 10.2 17.4 0.35 10.7 1.3 3.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain TFIIA PF03153.8 KII89716.1 - 1.3 8.8 14.5 1.5 8.6 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YyzF PF14116.1 KII89716.1 - 2.5 8.1 6.3 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 YyzF-like protein PAT1 PF09770.4 KII89716.1 - 7.4 4.6 25.1 8.7 4.4 17.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1768 PF08719.6 KII89717.1 - 4.4e-32 110.9 0.1 8.8e-32 110.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) PARP PF00644.15 KII89718.1 - 4.7e-16 58.8 0.0 3.3e-11 42.9 0.0 3.0 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 KII89719.1 - 3e-35 121.2 0.0 3.7e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1202 PF06717.6 KII89719.1 - 0.043 13.0 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Hepcidin PF06446.7 KII89720.1 - 0.043 14.2 0.5 0.043 14.2 0.3 2.2 2 0 0 2 2 2 0 Hepcidin Perm-CXXC PF15629.1 KII89720.1 - 0.13 12.3 2.3 0.4 10.7 1.6 1.9 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Ribosomal_L4 PF00573.17 KII89722.1 - 7.1e-45 152.7 1.0 1.2e-44 152.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KII89722.1 - 3.5e-28 97.3 5.3 3.5e-28 97.3 3.7 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Terpene_synth_C PF03936.11 KII89723.1 - 2.3e-07 30.3 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Allene_ox_cyc PF06351.6 KII89723.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Pkinase_Tyr PF07714.12 KII89725.1 - 9.5e-33 113.3 0.0 5.6e-32 110.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII89725.1 - 7.6e-27 94.0 0.0 2.6e-26 92.3 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KII89725.1 - 0.066 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ku PF02735.11 KII89726.1 - 2e-26 92.6 0.0 1.6e-25 89.7 0.0 2.1 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KII89726.1 - 1.6e-20 73.5 0.0 2.9e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KII89726.1 - 7.2e-10 38.1 0.2 1.3e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 KII89726.1 - 5.8e-05 23.5 1.2 9.8e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 KII89726.1 - 0.0017 18.4 0.0 0.0048 17.0 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 KII89726.1 - 0.065 12.7 0.2 0.27 10.8 0.1 2.0 1 1 0 1 1 1 0 HeH/LEM domain F-box-like PF12937.2 KII89728.1 - 0.019 14.6 0.6 0.05 13.3 0.4 1.8 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 KII89728.1 - 0.16 11.6 0.6 0.54 9.9 0.1 2.1 2 1 0 2 2 2 0 F-box domain DUF1295 PF06966.7 KII89729.1 - 7.7e-40 136.6 4.3 6.3e-39 133.6 3.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DAO PF01266.19 KII89732.1 - 1.5e-44 152.3 0.1 2e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII89732.1 - 3.2e-06 27.0 0.0 2.9e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII89732.1 - 2.1e-05 23.5 0.6 0.013 14.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KII89732.1 - 2.4e-05 24.4 0.0 0.00042 20.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII89732.1 - 0.0014 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KII89732.1 - 0.0035 16.4 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 KII89732.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KII89732.1 - 0.048 12.7 0.1 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KII89732.1 - 0.07 12.8 0.2 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KII89732.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.2 KII89733.1 - 8.1e-08 31.8 0.5 9.7e-07 28.4 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII89733.1 - 0.028 14.0 0.0 0.098 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box domain RRM_5 PF13893.1 KII89734.1 - 6.4e-07 29.1 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII89734.1 - 2.2e-06 27.1 0.1 3.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII89734.1 - 3.4e-05 23.7 0.1 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KII89734.1 - 0.0014 18.3 0.2 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2415 PF10313.4 KII89735.1 - 0.00023 20.7 0.0 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KII89735.1 - 0.00057 19.6 5.1 0.15 11.9 0.0 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat ABC_membrane PF00664.18 KII89736.1 - 5.9e-33 114.4 10.0 7.4e-33 114.1 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KII89736.1 - 6.6e-33 113.9 0.0 2e-32 112.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KII89736.1 - 5.3e-07 29.8 0.0 0.0066 16.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 KII89736.1 - 2.6e-06 26.8 0.6 0.0066 15.7 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KII89736.1 - 0.0012 18.3 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KII89736.1 - 0.0093 15.9 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KII89736.1 - 0.023 14.5 0.0 0.099 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KII89736.1 - 0.025 15.4 0.0 0.06 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KII89736.1 - 0.033 14.4 0.0 0.33 11.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KII89736.1 - 0.034 14.4 0.1 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KII89736.1 - 0.046 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KII89736.1 - 0.046 13.8 0.1 0.27 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KII89736.1 - 0.047 13.9 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KII89736.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KII89736.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 KII89736.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 KII89736.1 - 0.17 11.8 1.3 0.88 9.5 0.2 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit LRR_4 PF12799.2 KII89737.1 - 1.2e-23 82.2 30.5 2.1e-07 30.4 0.1 9.8 5 3 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII89737.1 - 5.1e-18 62.3 17.8 0.72 10.1 0.1 11.5 11 1 1 12 12 12 6 Leucine Rich Repeat LRR_8 PF13855.1 KII89737.1 - 5.6e-17 61.2 8.9 4e-11 42.4 1.8 8.1 5 3 3 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 KII89737.1 - 1.4e-14 52.4 17.2 0.79 9.9 0.0 11.1 12 0 0 12 12 12 5 Leucine Rich repeat LRR_7 PF13504.1 KII89737.1 - 1.1e-12 45.9 25.8 0.11 12.7 0.1 10.9 13 0 0 13 13 13 5 Leucine rich repeat zf-C2H2_4 PF13894.1 KII89739.1 - 1.2e-06 28.4 9.0 6.7e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII89739.1 - 7.7e-05 22.7 12.0 0.00016 21.8 2.7 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KII89739.1 - 0.00037 20.6 0.2 0.00037 20.6 0.2 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type IBR PF01485.16 KII89739.1 - 0.044 13.6 0.6 0.079 12.8 0.4 1.4 1 0 0 1 1 1 0 IBR domain zf-H2C2_2 PF13465.1 KII89741.1 - 3.6e-06 26.9 6.6 0.0045 17.2 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII89741.1 - 0.00043 20.4 17.4 0.0088 16.3 3.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-RING_3 PF14369.1 KII89741.1 - 0.0086 16.0 0.5 5.8 7.0 0.1 2.8 2 0 0 2 2 2 2 zinc-finger zf-MIZ PF02891.15 KII89741.1 - 0.32 10.5 0.1 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-met PF12874.2 KII89741.1 - 0.61 10.3 7.7 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type F-box-like PF12937.2 KII89744.1 - 9.1e-08 31.7 0.0 2.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Pyr_redox_2 PF07992.9 KII89745.1 - 1.8e-31 109.6 0.0 4.3e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KII89745.1 - 4.8e-16 58.1 0.0 1.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KII89745.1 - 1.2e-13 51.6 0.4 7.5e-06 26.1 0.0 3.3 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII89745.1 - 7.3e-12 45.5 6.5 9.2e-10 38.7 0.5 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KII89745.1 - 1.1e-07 31.9 0.0 4.4e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 KII89745.1 - 2e-05 23.6 0.2 0.039 12.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KII89745.1 - 0.0029 16.1 0.5 0.5 8.7 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 KII89745.1 - 0.0032 16.5 0.1 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KII89745.1 - 0.0038 17.4 0.9 0.037 14.2 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 KII89745.1 - 0.015 14.1 3.4 3.3 6.5 0.1 3.1 1 1 0 3 3 3 0 FAD dependent oxidoreductase Glyco_tran_WecB PF03808.8 KII89745.1 - 0.057 12.8 0.1 0.91 8.9 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Cys_Met_Meta_PP PF01053.15 KII89746.1 - 1.9e-129 431.3 0.0 2.5e-129 430.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 KII89746.1 - 9.7e-18 64.0 0.0 9.7e-18 64.0 0.0 3.0 4 0 0 4 4 4 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KII89746.1 - 5.7e-05 23.2 0.2 0.0002 21.5 0.1 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Beta_elim_lyase PF01212.16 KII89746.1 - 6.6e-05 22.1 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KII89746.1 - 0.00015 20.9 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KII89746.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GalKase_gal_bdg PF10509.4 KII89746.1 - 0.002 17.3 0.0 0.0041 16.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.6 KII89746.1 - 0.0028 16.0 0.0 0.0089 14.3 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase zf-HIT PF04438.11 KII89747.1 - 4.7e-07 29.3 10.2 8e-07 28.5 7.1 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.8 KII89747.1 - 0.45 8.1 2.6 0.62 7.6 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 HMGL-like PF00682.14 KII89748.1 - 8.5e-72 241.6 0.7 1.8e-71 240.5 0.5 1.6 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.1 KII89748.1 - 0.024 14.7 0.2 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain DUF1387 PF07139.6 KII89749.1 - 0.5 9.9 13.1 0.28 10.7 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) Response_reg PF00072.19 KII89750.1 - 3.6e-16 59.1 0.0 2.4e-15 56.4 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KII89750.1 - 1.8e-14 53.3 0.0 3.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KII89750.1 - 4.4e-13 49.0 0.0 1.3e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CTP_transf_1 PF01148.15 KII89750.1 - 3.8e-08 33.2 8.9 1.8e-07 31.0 6.2 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family GAF PF01590.21 KII89750.1 - 4.7e-07 30.0 0.1 1.7e-05 24.9 0.0 3.1 2 1 0 2 2 2 1 GAF domain GAF_3 PF13492.1 KII89750.1 - 0.00012 22.2 0.0 0.019 15.0 0.0 2.9 2 1 0 2 2 2 1 GAF domain DUF3895 PF13034.1 KII89750.1 - 0.51 9.8 0.0 1.6 8.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) UDG PF03167.14 KII89751.1 - 1.2e-22 80.0 0.1 3.2e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily bZIP_1 PF00170.16 KII89752.1 - 2.6e-05 24.0 2.6 4.5e-05 23.3 1.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KII89752.1 - 0.00084 19.1 1.3 0.0017 18.1 0.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Shugoshin_N PF07558.6 KII89752.1 - 0.012 15.3 2.1 0.033 13.8 0.2 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.1 KII89752.1 - 0.19 11.3 0.2 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif Helicase_C_3 PF13625.1 KII89754.1 - 5.4e-28 97.3 0.1 3.4e-27 94.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII89754.1 - 8.3e-16 58.3 0.3 5e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KII89754.1 - 1.7e-13 50.0 0.1 2.9e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII89754.1 - 7.3e-11 41.7 0.0 1.8e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.18 KII89755.1 - 1.3e-11 43.8 7.7 1.7e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KII89755.1 - 1.1e-06 28.1 3.6 0.0022 17.7 1.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KII89755.1 - 2.2e-05 24.0 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KII89755.1 - 0.0003 20.3 0.0 0.0007 19.1 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 KII89755.1 - 0.00056 19.5 6.2 0.19 11.4 0.3 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KII89755.1 - 0.0013 18.3 6.1 0.28 10.8 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 KII89755.1 - 0.046 13.7 5.2 0.11 12.5 3.6 1.6 1 0 0 1 1 1 0 DnaJ central domain CCDC-167 PF15188.1 KII89755.1 - 1.7 8.6 5.3 1 9.3 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-CCHC_2 PF13696.1 KII89755.1 - 8.2 6.0 10.2 0.63 9.5 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle Nol1_Nop2_Fmu PF01189.12 KII89756.1 - 3.3e-22 79.1 0.0 6.9e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family Dehydratase_SU PF02287.10 KII89756.1 - 0.0067 16.1 0.7 0.085 12.5 0.0 2.2 2 0 0 2 2 2 1 Dehydratase small subunit Fibrillarin PF01269.12 KII89756.1 - 0.022 13.6 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin DnaJ PF00226.26 KII89757.1 - 1.2e-25 89.0 0.1 2e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KII89757.1 - 1.1e-21 76.5 0.4 6.1e-20 70.9 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KII89757.1 - 1.7e-11 43.9 19.4 2.9e-11 43.2 13.5 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KII89757.1 - 0.0089 15.7 8.5 0.079 12.6 1.6 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KII89757.1 - 0.034 14.4 3.1 0.08 13.2 2.2 1.6 1 0 0 1 1 1 0 Cytochrome c3 DZR PF12773.2 KII89757.1 - 1.3 8.8 8.9 1.6 8.6 1.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Coiled PF05710.7 KII89757.1 - 6.5 7.3 6.3 1.1 9.8 0.2 2.3 1 1 0 2 2 2 0 Coiled coil ThuA PF06283.6 KII89758.1 - 9.3e-54 182.4 0.0 1.1e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation CIA30 PF08547.7 KII89759.1 - 2.7e-24 85.7 0.0 3.4e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) IMS PF00817.15 KII89760.1 - 6.9e-40 136.2 0.0 1.1e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KII89760.1 - 1.1e-12 48.0 0.0 2.7e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain TFIIS_C PF01096.13 KII89760.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) IMS_HHH PF11798.3 KII89760.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Dicty_CAR PF05462.6 KII89761.1 - 0.028 13.2 1.7 0.047 12.5 1.2 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Ras PF00071.17 KII89762.1 - 4.3e-58 195.2 0.2 5e-58 195.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII89762.1 - 7.3e-20 71.6 0.0 1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII89762.1 - 7.8e-09 34.9 0.0 9.5e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII89762.1 - 1.6e-06 27.6 0.1 3.4e-06 26.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KII89762.1 - 0.0032 16.7 0.1 0.0078 15.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KII89762.1 - 0.0052 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ser_hydrolase PF06821.8 KII89762.1 - 0.056 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.12 KII89762.1 - 0.1 12.0 1.7 0.98 8.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KII89762.1 - 0.13 11.6 0.2 0.98 8.8 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.24 KII89763.1 - 1.2e-37 129.0 0.0 5.7e-37 126.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII89763.1 - 5.4e-21 74.2 0.1 1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII89763.1 - 4.9e-10 39.5 0.0 8.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KII89763.1 - 0.036 14.2 0.7 1.2 9.2 0.5 2.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KII89763.1 - 0.039 13.7 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_membrane PF00664.18 KII89764.1 - 2.8e-62 210.6 30.5 2.8e-32 112.2 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII89764.1 - 4.7e-50 169.4 0.0 2.7e-28 98.9 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII89764.1 - 5.5e-08 33.1 0.0 0.016 15.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KII89764.1 - 1.7e-07 30.6 1.2 0.015 14.5 0.1 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KII89764.1 - 4.5e-07 29.4 0.5 0.0048 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KII89764.1 - 1.7e-05 25.2 0.3 0.37 11.0 0.2 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KII89764.1 - 4e-05 22.8 0.3 0.094 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KII89764.1 - 5.2e-05 22.8 0.0 0.042 13.3 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KII89764.1 - 8.8e-05 22.4 1.0 0.059 13.3 0.2 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KII89764.1 - 0.00014 21.3 0.8 0.27 10.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KII89764.1 - 0.00015 21.8 0.9 0.2 11.6 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 KII89764.1 - 0.00075 19.9 2.1 1.1 9.8 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 KII89764.1 - 0.002 18.2 3.4 0.62 10.2 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KII89764.1 - 0.0036 18.1 1.5 0.81 10.5 0.5 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KII89764.1 - 0.014 15.0 4.0 2.1 7.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KII89764.1 - 0.032 13.9 2.8 0.73 9.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KII89764.1 - 0.051 13.3 1.8 0.21 11.3 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain AAA_10 PF12846.2 KII89764.1 - 0.052 12.9 0.0 8.6 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 KII89764.1 - 0.059 12.8 4.1 24 4.3 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KII89764.1 - 0.066 13.3 0.1 17 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 KII89764.1 - 0.09 12.5 2.9 7 6.4 0.0 2.9 3 0 0 3 3 3 0 Dynamin family T2SE PF00437.15 KII89764.1 - 0.13 11.1 0.2 9.5 5.0 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein NACHT PF05729.7 KII89764.1 - 0.21 11.2 2.0 0.47 10.1 0.2 2.2 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KII89764.1 - 0.26 11.4 5.4 1.7 8.8 0.4 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 KII89764.1 - 0.3 9.6 3.8 2 6.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 KII89764.1 - 0.31 10.8 2.3 0.73 9.6 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 UPF0079 PF02367.12 KII89764.1 - 0.35 10.5 2.6 0.56 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KII89764.1 - 0.39 9.7 3.4 6.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 KII89764.1 - 0.61 9.9 3.6 8.8 6.1 0.2 3.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KII89764.1 - 3.2 8.0 4.6 41 4.4 0.6 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KII89764.1 - 6 6.2 7.3 0.73 9.2 0.2 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Asp PF00026.18 KII89765.1 - 4.6e-68 229.7 1.6 5.6e-68 229.5 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII89765.1 - 4.7e-07 29.9 0.1 1.2e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII89765.1 - 0.0019 18.6 0.1 3.2 8.3 0.0 3.7 3 0 0 3 3 3 1 Aspartyl protease DLH PF01738.13 KII89766.1 - 9.5e-20 70.8 0.0 1.5e-19 70.1 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 KII89766.1 - 0.00024 20.0 0.0 0.00032 19.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KII89766.1 - 0.00028 19.7 0.0 0.00037 19.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.2 KII89766.1 - 0.00047 19.9 0.0 0.00068 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Transposase_21 PF02992.9 KII89767.1 - 1.5e-13 50.3 0.0 4.6e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 KII89767.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HMG_box PF00505.14 KII89771.1 - 1.3e-10 41.3 0.0 2.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII89771.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain MOZ_SAS PF01853.13 KII89773.1 - 1.1e-75 252.9 0.0 1.7e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KII89773.1 - 7.7e-15 54.3 27.6 2.2e-09 36.8 4.5 3.3 2 1 1 3 3 3 2 PHD-finger Elf1 PF05129.8 KII89773.1 - 0.28 10.8 5.7 0.067 12.8 1.0 2.2 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-PHD-like PF15446.1 KII89773.1 - 4.8 6.4 15.0 1.4 8.1 1.3 2.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Pkinase PF00069.20 KII89775.1 - 4.3e-56 189.9 0.0 5.9e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89775.1 - 4.6e-18 65.2 0.0 1.2e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII89775.1 - 0.13 11.9 1.8 4.4 6.9 0.3 2.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Asp PF00026.18 KII89778.1 - 3.6e-64 217.0 5.9 4.3e-64 216.7 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII89778.1 - 2.9e-05 24.0 1.9 2.9e-05 24.0 1.3 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal ECH PF00378.15 KII89779.1 - 7.1e-24 84.2 0.0 1.1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family p450 PF00067.17 KII89780.1 - 6.8e-73 245.7 0.0 9.7e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NDUFB10 PF10249.4 KII89783.1 - 0.01 15.9 0.6 0.012 15.7 0.4 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 MitoNEET_N PF10660.4 KII89784.1 - 0.026 14.3 0.1 0.058 13.2 0.1 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus WD40 PF00400.27 KII89785.1 - 6.9e-23 79.6 4.0 2.3e-06 27.2 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat RNA_pol_Rpb5_C PF01191.14 KII89786.1 - 2.6e-35 119.8 0.2 4.8e-35 118.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KII89786.1 - 5.2e-28 97.3 0.0 8.8e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KII89786.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Restriction endonuclease PDEase_I PF00233.14 KII89786.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Terpene_synth_C PF03936.11 KII89787.1 - 1.5e-08 34.1 0.5 3.3e-08 33.0 0.4 1.5 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain ABC_membrane PF00664.18 KII89788.1 - 2e-53 181.5 30.8 4.1e-28 98.5 5.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII89788.1 - 3e-48 163.5 0.0 7.9e-28 97.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII89788.1 - 8.4e-09 35.7 2.2 0.089 12.7 0.0 4.3 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 KII89788.1 - 2.2e-06 27.0 3.7 0.0042 16.3 0.8 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KII89788.1 - 7.7e-05 22.1 0.1 0.18 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII89788.1 - 0.00011 21.6 0.3 0.72 9.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KII89788.1 - 0.00022 21.1 1.8 0.13 12.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KII89788.1 - 0.00028 20.9 2.0 0.083 12.8 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KII89788.1 - 0.00029 21.2 1.5 0.63 10.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KII89788.1 - 0.00038 19.6 0.6 0.39 9.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KII89788.1 - 0.00067 19.4 0.1 0.018 14.7 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 KII89788.1 - 0.0031 17.4 0.4 5.9 6.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KII89788.1 - 0.012 14.7 0.4 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 KII89788.1 - 0.022 14.4 0.2 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 KII89788.1 - 0.03 14.4 1.5 2.6 8.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.10 KII89788.1 - 0.034 12.7 0.0 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_23 PF13476.1 KII89788.1 - 0.039 14.2 0.3 8.3 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KII89788.1 - 0.04 13.6 0.7 5.3 6.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KII89788.1 - 0.041 13.3 2.6 6.8 6.0 0.3 3.0 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KII89788.1 - 0.078 13.7 3.0 17 6.2 0.1 3.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KII89788.1 - 0.091 12.6 0.8 3.8 7.4 0.1 3.6 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.18 KII89788.1 - 0.16 11.7 5.0 3.6 7.3 0.2 2.5 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 KII89788.1 - 0.2 11.8 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 KII89788.1 - 6.8 6.4 5.2 1.4 8.6 0.5 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 C2 PF00168.25 KII89789.1 - 3.1e-10 39.7 0.0 5.4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain p450 PF00067.17 KII89790.1 - 3.8e-71 239.9 0.0 5.7e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII89791.1 - 1.9e-76 257.4 0.0 2.6e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KII89792.1 - 0.011 15.4 0.3 0.029 14.0 0.2 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KII89793.1 - 0.88 9.3 4.3 0.24 11.1 0.4 2.1 2 0 0 2 2 2 0 F-box-like Ku PF02735.11 KII89794.1 - 1.7e-24 86.3 0.0 7.5e-24 84.2 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KII89794.1 - 5.1e-20 71.8 0.0 1e-19 70.8 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KII89794.1 - 1.3e-09 37.2 0.2 1.3e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 SAP domain Ku_C PF03730.9 KII89794.1 - 0.00015 22.2 1.1 0.00024 21.5 0.1 1.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 KII89794.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 KII89794.1 - 0.072 12.6 0.2 0.28 10.7 0.1 1.9 1 1 0 1 1 1 0 HeH/LEM domain Frag1 PF10277.4 KII89796.1 - 2.4e-35 121.9 11.2 3e-35 121.6 7.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7TM_GPCR_Srh PF10318.4 KII89796.1 - 0.069 11.9 0.9 0.11 11.2 0.7 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Ribosomal_L23 PF00276.15 KII89800.1 - 0.052 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L23 DSBA PF01323.15 KII89801.1 - 5.3e-26 91.3 0.0 6.8e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 KII89801.1 - 0.0017 18.3 0.0 0.078 12.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 KII89801.1 - 0.019 14.7 0.2 0.058 13.2 0.0 1.9 2 1 0 2 2 2 0 Thioredoxin domain p450 PF00067.17 KII89803.1 - 7.9e-67 225.7 0.0 1.5e-66 224.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII89804.1 - 8.9e-72 242.0 0.0 1.4e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 KII89805.1 - 4.8 7.7 7.4 2 8.9 2.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII89805.1 - 8.6 6.9 7.8 7.4 7.1 3.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_27 PF13514.1 KII89806.1 - 0.011 13.4 7.9 0.015 13.0 5.4 1.1 1 0 0 1 1 1 0 AAA domain Osmo_CC PF08946.5 KII89806.1 - 0.034 14.1 0.7 0.078 13.0 0.5 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Ank_2 PF12796.2 KII89807.1 - 2.2e-23 82.3 3.7 4.5e-08 33.3 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII89807.1 - 2.3e-20 72.5 7.8 0.00014 22.2 0.1 6.5 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII89807.1 - 6.5e-20 70.7 3.2 1.3e-05 25.2 0.0 6.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KII89807.1 - 1.5e-19 68.7 5.1 5.3e-07 29.1 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KII89807.1 - 1.1e-17 62.3 0.1 0.00022 21.1 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat LRR_4 PF12799.2 KII89808.1 - 1.4e-08 34.1 6.5 2.8e-05 23.6 1.4 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) TAP_C PF03943.8 KII89808.1 - 1.7e-08 33.7 0.0 4.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 KII89808.1 - 6.4e-05 23.3 0.0 0.57 10.5 0.0 2.4 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_7 PF13504.1 KII89808.1 - 0.0013 18.5 0.5 39 5.0 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat UBA_4 PF14555.1 KII89808.1 - 0.018 14.5 0.7 0.066 12.7 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain LRR_6 PF13516.1 KII89808.1 - 0.073 13.1 1.1 26 5.2 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 KII89808.1 - 0.11 12.6 5.2 14 6.2 0.2 3.6 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 KII89808.1 - 0.13 11.9 3.7 0.7 9.6 2.1 2.4 1 1 1 2 2 2 0 Leucine rich repeat MFS_1 PF07690.11 KII89810.1 - 2.2e-34 118.7 61.7 3.4e-30 104.9 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII89810.1 - 0.0044 15.4 26.8 0.0061 15.0 10.0 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 KII89811.1 - 2.1e-26 92.5 56.7 2.9e-25 88.7 21.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PagP PF07017.6 KII89812.1 - 0.0018 17.5 0.1 0.0019 17.4 0.1 1.1 1 0 0 1 1 1 1 Antimicrobial peptide resistance and lipid A acylation protein PagP SPT2 PF08243.6 KII89813.1 - 5.1e-14 52.5 10.1 5.1e-14 52.5 7.0 4.1 2 1 2 4 4 4 1 SPT2 chromatin protein RRM_1 PF00076.17 KII89814.1 - 3.1e-06 26.7 0.0 5.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII89814.1 - 3.8e-06 26.7 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII89814.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPA PF08616.5 KII89815.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 KII89815.1 - 0.0042 17.0 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.16 KII89815.1 - 0.014 15.1 0.0 0.046 13.4 0.0 1.8 1 1 0 1 1 1 0 DENN (AEX-3) domain Pkinase PF00069.20 KII89818.1 - 9.7e-36 123.2 0.0 1.2e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89818.1 - 3e-12 46.1 0.0 3.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII89818.1 - 3.8e-05 23.5 0.0 0.28 10.8 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family PalH PF08733.5 KII89819.1 - 3.2 6.4 8.3 0.34 9.7 2.1 1.8 1 1 0 2 2 2 0 PalH/RIM21 DUF368 PF04018.8 KII89822.1 - 1 8.4 10.8 0.044 12.9 1.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF368) Tic20 PF09685.5 KII89822.1 - 9.8 6.2 16.7 24 4.9 5.6 3.2 1 1 1 2 2 2 0 Tic20-like protein MFS_1 PF07690.11 KII89830.1 - 4.9e-16 58.3 27.7 4.9e-16 58.3 19.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ALMT PF11744.3 KII89830.1 - 0.11 11.1 1.0 4.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Sterol-sensing PF12349.3 KII89832.1 - 0.071 12.5 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Acetate_kinase PF00871.12 KII89835.1 - 8.7e-85 284.5 0.0 2e-84 283.3 0.0 1.6 1 1 0 1 1 1 1 Acetokinase family Anth_synt_I_N PF04715.8 KII89835.1 - 0.031 14.3 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region XFP_N PF09364.5 KII89836.1 - 6.6e-153 508.7 0.0 8.5e-153 508.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KII89836.1 - 9.9e-70 233.7 0.0 1.7e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KII89836.1 - 8.6e-67 224.4 0.0 1.6e-66 223.6 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 KII89836.1 - 0.003 17.1 0.3 0.0072 15.9 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain p450 PF00067.17 KII89837.1 - 2.3e-66 224.2 0.0 5.8e-66 222.8 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Fasciclin PF02469.17 KII89837.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Fasciclin domain FA_hydroxylase PF04116.8 KII89841.1 - 4.7e-13 49.5 27.4 3e-12 46.9 16.4 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Vps39_1 PF10366.4 KII89843.1 - 1.4e-27 95.7 1.3 3.6e-27 94.5 0.1 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KII89843.1 - 7.3e-24 84.0 0.2 1.9e-23 82.7 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KII89843.1 - 9e-16 57.7 1.8 3.1e-11 43.0 0.1 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.17 KII89843.1 - 1e-12 48.0 0.0 3.1e-11 43.1 0.0 2.7 2 1 0 2 2 2 1 CNH domain TPR_1 PF00515.23 KII89843.1 - 0.039 13.5 4.6 9.2 6.0 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KII89843.1 - 0.086 13.5 7.0 14 6.4 0.0 4.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII89843.1 - 0.15 12.8 4.7 6.7 7.6 0.2 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII89843.1 - 0.28 11.5 3.9 0.3 11.4 0.0 3.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII89843.1 - 1.7 8.7 5.3 1e+02 3.1 0.6 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 KII89844.1 - 4e-30 102.5 7.7 7.4e-08 31.9 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KII89844.1 - 0.00087 19.0 0.1 0.21 11.2 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ADH_zinc_N PF00107.21 KII89845.1 - 1.3e-16 60.2 0.1 3.4e-16 58.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII89845.1 - 4.6e-16 59.8 0.0 9.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII89845.1 - 6.3e-14 51.6 0.1 2.9e-11 43.0 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KII89845.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF1295 PF06966.7 KII89846.1 - 2.4e-46 157.9 0.1 3e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KII89846.1 - 0.00014 22.0 0.1 0.00048 20.2 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KII89846.1 - 0.00048 18.7 0.1 0.001 17.7 0.1 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 KII89846.1 - 0.003 17.6 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KII89846.1 - 0.069 12.9 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase p450 PF00067.17 KII89847.1 - 3.4e-68 230.2 0.0 4.2e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SIR2 PF02146.12 KII89849.1 - 2.2e-27 95.9 0.2 6.9e-19 68.2 0.0 3.0 2 1 0 2 2 2 2 Sir2 family BmKX PF09132.5 KII89849.1 - 0.092 12.6 0.0 0.092 12.6 0.0 2.1 2 0 0 2 2 2 0 BmKX TPP_enzyme_M PF00205.17 KII89849.1 - 0.12 12.1 0.1 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF2413 PF10310.4 KII89849.1 - 1.2 7.8 6.2 2 7.1 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DSS1_SEM1 PF05160.8 KII89850.1 - 1.4e-20 72.7 11.0 3.7e-20 71.4 7.6 1.6 1 1 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.19 KII89851.1 - 2.9e-33 115.1 34.7 2.9e-20 72.3 7.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KII89851.1 - 2.1e-18 66.1 61.9 6.8e-18 64.5 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII89851.1 - 0.0007 18.1 25.3 0.001 17.5 1.2 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein DUF2839 PF10999.3 KII89851.1 - 0.06 13.3 0.1 0.44 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) PGAP1 PF07819.8 KII89852.1 - 0.046 13.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein APG6 PF04111.7 KII89852.1 - 0.084 11.8 2.0 0.16 10.9 1.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Alpha-amylase PF00128.19 KII89853.1 - 2.7e-18 66.4 0.0 3.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KII89853.1 - 3.3e-05 23.9 0.0 9.9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 KII89853.1 - 0.06 12.2 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme COesterase PF00135.23 KII89856.1 - 5.9e-96 322.2 0.0 7.2e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII89856.1 - 5.3e-08 32.6 0.1 9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1168 PF06658.7 KII89856.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Amidohydro_4 PF13147.1 KII89857.1 - 1.1e-20 74.8 13.5 3.8e-20 73.0 1.8 3.4 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KII89857.1 - 9.1e-13 47.8 0.0 4.1e-09 36.1 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 KII89857.1 - 3.4e-12 46.6 0.1 2.8e-08 33.7 0.0 3.3 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 KII89857.1 - 3.6e-09 36.3 0.2 3.3e-06 26.5 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Ank PF00023.25 KII89857.1 - 0.072 12.9 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat HIT PF01230.18 KII89858.1 - 3e-22 78.9 0.1 4.2e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KII89858.1 - 6.3e-12 45.7 0.1 8.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KII89858.1 - 0.06 12.9 0.6 0.18 11.4 0.5 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 MBOAT_2 PF13813.1 KII89859.1 - 3.3e-16 59.1 2.6 3.3e-16 59.1 1.8 2.2 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family NPR3 PF03666.8 KII89860.1 - 4e-55 187.1 2.0 5.1e-55 186.8 0.0 2.1 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 AvrL567-A PF11529.3 KII89860.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A TFIIE_alpha PF02002.12 KII89860.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit Epimerase PF01370.16 KII89861.1 - 2e-22 79.7 0.0 3.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII89861.1 - 1.1e-14 54.8 0.0 1.6e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII89861.1 - 4.3e-09 35.4 0.0 5.4e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KII89861.1 - 2.1e-06 27.1 0.1 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KII89861.1 - 9e-06 24.7 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.15 KII89861.1 - 0.00011 22.0 0.2 0.00018 21.4 0.1 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KII89861.1 - 0.002 17.2 0.1 0.0027 16.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase HTH_8 PF02954.14 KII89861.1 - 0.0033 16.9 0.3 0.44 10.1 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family TrkA_N PF02254.13 KII89861.1 - 0.0079 16.1 0.1 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 KII89861.1 - 0.045 13.6 0.1 0.093 12.6 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.18 KII89861.1 - 0.046 13.5 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KII89861.1 - 0.087 13.2 0.1 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SAD_SRA PF02182.12 KII89862.1 - 9.9e-37 125.6 1.7 3.4e-36 123.8 0.2 2.0 2 0 0 2 2 2 1 SAD/SRA domain Mucin PF01456.12 KII89862.1 - 1.2 8.9 6.1 2.8 7.6 2.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Abhydrolase_6 PF12697.2 KII89869.1 - 1.9e-13 50.8 0.6 6.1e-08 32.8 0.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII89869.1 - 2.2e-11 43.7 0.0 3.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KII89869.1 - 9.1e-10 38.4 0.0 1.7e-09 37.4 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KII89869.1 - 3.1e-09 36.7 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII89869.1 - 0.0046 16.2 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family VirJ PF06057.6 KII89869.1 - 0.019 14.7 0.0 0.065 13.0 0.0 1.8 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KII89869.1 - 0.034 13.7 0.0 0.088 12.4 0.0 1.7 1 1 1 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.3 KII89869.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase PE-PPE PF08237.6 KII89869.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 PE-PPE domain FSH1 PF03959.8 KII89869.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) SAD_SRA PF02182.12 KII89870.1 - 1.2e-38 131.8 0.3 1.5e-38 131.5 0.2 1.1 1 0 0 1 1 1 1 SAD/SRA domain SAD_SRA PF02182.12 KII89871.1 - 3.6e-35 120.5 0.0 1e-32 112.6 0.0 2.3 2 0 0 2 2 2 2 SAD/SRA domain E1-E2_ATPase PF00122.15 KII89872.1 - 9.5e-57 191.6 0.4 9.5e-57 191.6 0.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KII89872.1 - 2e-46 157.8 8.3 2e-46 157.8 5.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KII89872.1 - 1.5e-25 90.8 0.0 1.3e-24 87.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII89872.1 - 5.7e-20 71.0 0.0 2e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KII89872.1 - 9.8e-16 58.4 0.0 1.4e-14 54.7 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KII89872.1 - 1.8e-08 33.7 0.2 7e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KII89872.1 - 3.1e-05 23.7 0.3 0.0025 17.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Apq12 PF12716.2 KII89872.1 - 0.02 14.5 2.2 0.12 12.1 1.5 2.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Hep_core_N PF08290.6 KII89873.1 - 1.7 8.1 7.0 0.83 9.1 2.8 2.2 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger TPR_11 PF13414.1 KII89874.1 - 5e-06 26.0 5.3 8.7e-06 25.2 1.1 3.0 2 1 1 3 3 3 2 TPR repeat Methyltransf_25 PF13649.1 KII89875.1 - 6.1e-07 29.7 0.0 1.8e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII89875.1 - 0.00031 20.5 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII89875.1 - 0.0085 16.6 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 KII89876.1 - 2.6e-51 174.2 0.0 4e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII89876.1 - 2.4e-25 89.0 0.0 1.1e-21 77.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KII89876.1 - 7e-05 22.6 0.4 0.029 14.1 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 KII89876.1 - 0.00045 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KII89876.1 - 0.0033 16.4 0.0 14 4.5 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Macoilin PF09726.4 KII89877.1 - 0.00012 20.5 13.7 0.00012 20.5 9.5 1.9 2 0 0 2 2 2 1 Transmembrane protein FliJ PF02050.11 KII89877.1 - 0.003 17.5 19.6 0.003 17.5 13.6 3.5 3 1 1 4 4 4 1 Flagellar FliJ protein Baculo_PEP_C PF04513.7 KII89877.1 - 0.013 15.3 3.1 0.032 14.0 2.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KII89877.1 - 0.018 14.6 37.0 0.017 14.7 17.6 2.8 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 KII89877.1 - 0.19 11.5 38.1 0.89 9.3 4.8 2.8 1 1 1 2 2 2 0 Tropomyosin like DUF724 PF05266.9 KII89877.1 - 0.39 10.3 26.2 0.018 14.6 7.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) YwqJ-deaminase PF14431.1 KII89877.1 - 0.4 10.5 4.6 0.57 10.0 1.5 2.2 2 0 0 2 2 2 0 YwqJ-like deaminase Reo_sigmaC PF04582.7 KII89877.1 - 0.8 8.8 6.7 0.96 8.5 3.6 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tnp_P_element PF12017.3 KII89877.1 - 0.97 8.6 11.7 2.8 7.1 2.5 2.7 1 1 1 2 2 2 0 Transposase protein Spc24 PF08286.6 KII89877.1 - 1.1 8.9 26.1 2.5 7.8 3.5 3.9 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FliD_N PF02465.13 KII89877.1 - 1.4 9.3 17.2 0.69 10.3 1.4 3.9 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus ADIP PF11559.3 KII89877.1 - 3.8 7.3 34.6 0.43 10.4 15.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KII89877.1 - 4.6 7.0 37.5 5 6.8 18.8 3.7 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.6 KII89877.1 - 5.8 6.8 15.7 4.9 7.0 0.2 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) SH3_9 PF14604.1 KII89878.1 - 0.0022 17.5 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SNN_transmemb PF09049.5 KII89878.1 - 0.034 13.8 1.4 0.063 12.9 1.0 1.4 1 0 0 1 1 1 0 Stannin transmembrane NmrA PF05368.8 KII89879.1 - 2.4e-34 118.5 0.0 3.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII89879.1 - 6.4e-07 29.5 0.0 8.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII89879.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII89879.1 - 0.081 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acyl-CoA_dh_1 PF00441.19 KII89880.1 - 3.8e-30 104.9 2.7 5.4e-30 104.4 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII89880.1 - 4e-18 64.6 0.8 8e-18 63.6 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KII89880.1 - 1.7e-16 59.7 0.0 3.9e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KII89880.1 - 2.4e-08 34.5 0.0 8.2e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KII89880.1 - 2e-05 24.8 1.5 3.8e-05 23.9 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Piwi PF02171.12 KII89880.1 - 0.11 11.4 0.3 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Piwi domain LysM PF01476.15 KII89881.1 - 1.2e-05 25.0 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain APG17 PF04108.7 KII89882.1 - 4.5e-41 140.9 21.6 4.7e-40 137.6 15.0 2.1 1 1 0 1 1 1 1 Autophagy protein Apg17 Herpes_UL36 PF03586.8 KII89882.1 - 0.0029 16.7 1.8 0.0029 16.7 1.3 2.1 2 0 0 2 2 2 1 Herpesvirus UL36 tegument protein K-box PF01486.12 KII89882.1 - 0.017 14.8 1.2 0.017 14.8 0.8 2.6 2 0 0 2 2 2 0 K-box region FTO_CTD PF12934.2 KII89882.1 - 0.15 11.6 4.5 0.22 11.0 0.5 2.8 1 1 1 2 2 2 0 FTO C-terminal domain UPF0184 PF03670.8 KII89882.1 - 1.4 9.1 9.6 2 8.6 0.2 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Syntaxin-6_N PF09177.6 KII89882.1 - 4.6 7.7 10.5 0.4 11.1 0.7 3.4 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Herpes_gE PF02480.11 KII89883.1 - 0.049 11.8 0.1 0.073 11.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 KII89883.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SCF PF02404.10 KII89883.1 - 0.099 11.8 5.3 0.16 11.1 3.7 1.2 1 0 0 1 1 1 0 Stem cell factor Acyl-CoA_dh_1 PF00441.19 KII89884.1 - 2.3e-29 102.4 0.3 3.5e-29 101.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KII89884.1 - 1.9e-20 72.4 0.1 9.1e-20 70.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KII89884.1 - 2.9e-19 68.3 0.5 5.9e-19 67.3 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KII89884.1 - 2.8e-12 47.1 0.0 6.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain COLFI PF01410.13 KII89884.1 - 0.0088 15.4 1.1 1.5 8.1 0.2 2.2 2 0 0 2 2 2 2 Fibrillar collagen C-terminal domain DUF3997 PF13162.1 KII89884.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Fungal_trans PF04082.13 KII89885.1 - 1.6e-10 40.2 1.3 2.9e-10 39.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII89885.1 - 0.00096 19.0 11.8 0.0017 18.1 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZZ PF00569.12 KII89885.1 - 1.2 8.7 6.6 3.6 7.1 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type CoA_transf_3 PF02515.12 KII89886.1 - 6.9e-42 142.8 0.0 9.3e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Actin PF00022.14 KII89887.1 - 1.4e-88 296.9 0.0 2e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Actin NAD_binding_10 PF13460.1 KII89888.1 - 1e-08 35.4 0.4 1.6e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII89888.1 - 1.2e-06 27.9 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KII89888.1 - 3.9e-06 26.4 0.0 2.4e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KII89888.1 - 1.8e-05 23.7 0.0 5.5e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KII89888.1 - 2.3e-05 24.7 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KII89888.1 - 0.0028 16.4 0.0 0.035 12.8 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KII89888.1 - 0.0032 16.5 0.1 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KII89888.1 - 0.04 12.8 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KII89888.1 - 0.052 13.9 0.1 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 KII89888.1 - 0.14 12.5 0.2 1.6 9.1 0.0 2.5 2 1 1 3 3 3 0 Homoserine dehydrogenase, NAD binding domain Epimerase PF01370.16 KII89889.1 - 1.8e-07 30.8 0.1 3.5e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII89889.1 - 1.4e-06 27.7 0.2 2.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KII89889.1 - 1.3e-05 24.2 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KII89889.1 - 1.3e-05 25.4 0.1 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KII89889.1 - 4.1e-05 23.6 0.3 7e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KII89889.1 - 0.0018 17.3 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KII89889.1 - 0.0021 16.8 0.0 0.0032 16.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KII89889.1 - 0.0099 16.2 0.2 0.024 15.0 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KII89889.1 - 0.032 14.3 0.2 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 KII89889.1 - 0.045 13.3 0.2 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 KII89889.1 - 0.059 13.2 2.7 0.29 11.0 1.9 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Ala_racemase_N PF01168.15 KII89890.1 - 3.5e-39 134.6 0.0 4.4e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Epimerase PF01370.16 KII89891.1 - 1.1e-07 31.6 0.0 4.1e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII89891.1 - 1.7e-07 30.7 0.1 4.4e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KII89891.1 - 2.3e-06 27.7 0.1 3.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII89891.1 - 0.00019 20.4 0.0 0.00088 18.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KII89891.1 - 0.0019 18.5 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KII89891.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII89892.1 - 1.8e-07 30.8 0.0 0.0069 15.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KII89892.1 - 1.7e-05 24.2 0.1 5.3e-05 22.5 0.0 1.8 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KII89892.1 - 8.1e-05 22.7 0.1 0.00025 21.1 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KII89892.1 - 9.2e-05 22.7 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII89892.1 - 0.00017 20.6 0.0 0.00041 19.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 KII89892.1 - 0.024 13.6 0.1 0.045 12.7 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NAD_binding_3 PF03447.11 KII89892.1 - 0.072 13.4 0.2 0.27 11.6 0.0 2.0 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KII89892.1 - 0.14 10.8 0.0 0.29 9.8 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KII89892.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C2 PF00168.25 KII89893.1 - 2.6e-06 27.1 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain Alpha-L-AF_C PF06964.7 KII89894.1 - 1.4e-33 116.1 0.0 2.2e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydro_79n PF03662.9 KII89894.1 - 0.051 12.2 0.1 0.089 11.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Sugar_tr PF00083.19 KII89895.1 - 4.5e-98 328.7 24.3 1.7e-97 326.8 16.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII89895.1 - 2.4e-28 98.8 40.3 3e-26 91.9 12.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 KII89896.1 - 2e-08 33.8 0.4 5.4e-08 32.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KII89896.1 - 0.053 13.2 0.9 0.36 10.5 0.4 2.6 2 1 0 2 2 2 0 F-box-like domain adh_short PF00106.20 KII89897.1 - 3.5e-65 218.9 17.6 8.9e-34 116.8 3.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KII89897.1 - 3.8e-31 108.1 12.4 8.2e-17 61.4 1.8 2.2 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.13 KII89897.1 - 0.00011 21.9 10.5 0.035 13.7 0.8 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KII89897.1 - 0.00015 20.9 3.0 0.016 14.2 0.2 3.1 2 1 1 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 KII89897.1 - 0.0028 16.8 1.7 0.039 13.0 0.1 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4161 PF13722.1 KII89897.1 - 0.0043 17.3 2.3 0.39 11.0 0.0 2.6 2 1 0 2 2 2 1 C-terminal domain on CstA (DUF4161) Phage_portal_2 PF05136.8 KII89897.1 - 0.038 12.5 0.0 1.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Phage portal protein, lambda family Dfp1_Him1_M PF08630.5 KII89897.1 - 0.068 12.9 0.1 13 5.5 0.0 3.1 3 0 0 3 3 3 0 Dfp1/Him1, central region DUF543 PF04418.7 KII89897.1 - 0.1 12.5 6.8 1.5 8.8 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Shikimate_DH PF01488.15 KII89897.1 - 0.14 12.2 4.4 7.1 6.7 0.4 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cyclin_N PF00134.18 KII89899.1 - 7e-43 145.2 0.2 1.1e-41 141.3 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KII89899.1 - 3.4e-24 85.0 0.0 6e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain G-patch PF01585.18 KII89901.1 - 1.5e-07 31.0 0.3 2.5e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 KII89901.1 - 7.1e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 KII89902.1 - 1.7 7.0 8.7 2 6.7 6.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2945 PF11160.3 KII89904.1 - 0.0001 22.0 0.4 0.03 14.1 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) DUF1918 PF08940.6 KII89904.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) CsgF PF10614.4 KII89904.1 - 0.09 12.7 0.3 0.11 12.5 0.2 1.1 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein CBM_5_12 PF02839.9 KII89904.1 - 2 8.0 5.3 2.1 7.9 0.5 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain TOM13 PF08219.6 KII89905.1 - 8.1e-13 47.9 0.1 2.5e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Outer membrane protein TOM13 Na_Ca_ex PF01699.19 KII89906.1 - 5.7e-35 119.9 35.2 1.1e-19 70.4 7.7 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Vma12 PF11712.3 KII89906.1 - 0.035 13.8 0.7 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1510 PF07423.6 KII89906.1 - 0.098 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NMN_transporter PF04973.7 KII89906.1 - 3.2 7.1 12.2 0.84 9.0 0.3 4.1 4 1 0 4 4 4 0 Nicotinamide mononucleotide transporter Calc_CGRP_IAPP PF00214.14 KII89907.1 - 0.046 13.7 0.1 0.056 13.4 0.1 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family F-box-like PF12937.2 KII89910.1 - 0.00043 19.9 0.3 0.0014 18.2 0.2 1.9 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KII89910.1 - 0.0094 15.9 0.0 0.11 12.6 0.0 2.8 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.28 KII89910.1 - 0.089 12.8 0.7 2 8.7 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 KII89910.1 - 0.1 12.3 1.8 5.5 6.8 0.2 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 KII89910.1 - 0.14 11.8 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KII89911.1 - 0.00013 21.7 0.6 0.063 13.3 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 KII89911.1 - 0.0017 17.9 0.5 0.33 10.6 0.0 3.4 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII89911.1 - 0.0047 16.7 4.0 2.3 8.6 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 KII89911.1 - 0.3 10.8 3.6 6.7 6.5 0.2 4.0 3 1 1 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KII89911.1 - 1.6 9.2 6.9 28 5.5 0.1 5.5 6 0 0 6 6 6 0 Leucine rich repeat FAD_binding_3 PF01494.14 KII89912.1 - 3.8e-89 299.2 0.0 5.1e-89 298.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KII89912.1 - 4.5e-42 143.5 0.0 9.2e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KII89912.1 - 0.00047 20.1 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII89912.1 - 0.00073 18.1 0.1 0.0012 17.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KII89912.1 - 0.0017 17.1 0.1 0.0047 15.6 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 KII89912.1 - 0.0056 15.8 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KII89912.1 - 0.0062 15.4 0.0 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII89912.1 - 0.0063 15.4 0.1 0.016 14.1 0.1 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KII89912.1 - 0.011 15.6 0.1 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KII89912.1 - 0.034 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KII89912.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KII89912.1 - 0.063 12.8 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KII89912.1 - 0.099 11.4 0.1 0.23 10.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 KII89912.1 - 0.14 11.9 0.1 0.36 10.6 0.0 1.7 2 0 0 2 2 1 0 ThiF family Erg28 PF03694.8 KII89913.1 - 2.1e-36 124.2 5.2 2.7e-36 123.9 3.6 1.1 1 0 0 1 1 1 1 Erg28 like protein Herpes_BMRF2 PF04633.7 KII89913.1 - 0.004 16.1 2.5 0.005 15.8 1.7 1.3 1 1 0 1 1 1 1 Herpesvirus BMRF2 protein MaoC_dehydratas PF01575.14 KII89915.1 - 1.1e-29 102.2 0.0 2.3e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KII89915.1 - 1.1e-13 51.0 0.0 1.4e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF4078 PF13300.1 KII89916.1 - 1.7e-19 69.7 3.3 1.7e-19 69.7 2.3 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4078) DUF2203 PF09969.4 KII89916.1 - 1.2 9.3 4.6 1.7 8.9 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Lactamase_B PF00753.22 KII89917.1 - 3.3e-06 26.9 0.2 3.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ank_5 PF13857.1 KII89918.1 - 6.6e-15 54.8 0.2 1.5e-12 47.3 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KII89918.1 - 6.5e-13 48.8 0.0 3.6e-11 43.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII89918.1 - 1.5e-10 40.3 0.8 7.2e-07 28.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KII89918.1 - 1.9e-10 40.9 0.1 4.9e-06 26.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII89918.1 - 1.4e-07 31.0 0.1 9.3e-05 22.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat 7tm_2 PF00002.19 KII89919.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) PDE6_gamma PF04868.7 KII89919.1 - 0.11 12.3 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit F-box-like PF12937.2 KII89921.1 - 0.011 15.4 0.1 0.029 14.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like 7tm_2 PF00002.19 KII89921.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) ThiS PF02597.15 KII89924.1 - 0.00012 22.3 0.0 0.00014 22.2 0.0 1.1 1 0 0 1 1 1 1 ThiS family TPK_catalytic PF04263.11 KII89925.1 - 1.3e-24 86.0 0.0 1.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KII89925.1 - 4.8e-20 71.0 0.1 7.9e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CS PF04969.11 KII89926.1 - 2e-06 28.2 0.0 3.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 CS domain Terpene_synth_C PF03936.11 KII89927.1 - 2.1e-08 33.7 0.2 3e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain GATA PF00320.22 KII89928.1 - 8.3e-14 50.6 5.2 2e-13 49.4 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 KII89928.1 - 0.01 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 KII89928.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAP1 PF08601.5 KII89930.1 - 3.3 7.3 10.6 4.1 6.9 7.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 KII89930.1 - 4.4 5.4 9.7 4.8 5.3 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein PRMT5 PF05185.11 KII89931.1 - 6.6e-157 522.9 0.0 8.2e-157 522.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 KII89931.1 - 0.057 13.0 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein LRR_4 PF12799.2 KII89932.1 - 4.1e-41 137.9 44.7 2.4e-08 33.4 4.0 7.6 4 2 6 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII89932.1 - 1.1e-26 92.3 38.7 2.1e-10 40.1 2.8 5.9 3 2 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 KII89932.1 - 4.4e-16 58.9 10.8 3.7e-09 36.3 1.8 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 KII89932.1 - 4.6e-16 56.3 34.1 0.23 11.6 0.1 11.5 12 0 0 12 12 12 8 Leucine Rich Repeat LRR_6 PF13516.1 KII89932.1 - 4.4e-13 47.8 24.5 0.7 10.1 0.0 10.7 6 2 4 10 10 10 6 Leucine Rich repeat LRR_7 PF13504.1 KII89932.1 - 2.2e-09 35.9 26.8 1.2 9.6 0.1 10.9 11 1 1 12 12 12 4 Leucine rich repeat LRR_5 PF13306.1 KII89932.1 - 0.11 12.2 0.3 0.64 9.7 0.0 2.1 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) PFK PF00365.15 KII89933.1 - 1.2e-159 529.7 2.2 3.7e-94 314.8 0.1 3.1 3 0 0 3 3 3 3 Phosphofructokinase DUF4646 PF15496.1 KII89933.1 - 0.035 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) FAM216B PF15107.1 KII89933.1 - 0.087 12.7 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 FAM216B protein family DUF3421 PF11901.3 KII89935.1 - 6e-15 55.0 0.0 8.2e-11 41.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) KilA-N PF04383.8 KII89936.1 - 0.069 12.7 0.0 0.36 10.4 0.0 2.1 1 1 0 1 1 1 0 KilA-N domain DUF1687 PF07955.6 KII89936.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) DUF3835 PF12927.2 KII89936.1 - 0.18 12.7 4.9 0.44 11.5 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) PPP4R2 PF09184.6 KII89936.1 - 0.5 9.8 7.8 0.87 9.0 5.4 1.3 1 0 0 1 1 1 0 PPP4R2 WLM PF08325.5 KII89937.1 - 1e-53 181.9 0.4 3.2e-53 180.3 0.3 1.8 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KII89937.1 - 3.3e-06 26.0 0.7 7.6e-06 24.9 0.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KII89937.1 - 5e-06 26.4 0.2 1.1e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KII89937.1 - 0.0011 18.6 0.3 0.003 17.2 0.0 1.8 2 0 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 KII89937.1 - 0.03 14.3 0.8 0.067 13.2 0.1 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily Nop25 PF09805.4 KII89937.1 - 0.19 11.7 4.3 0.35 10.9 3.0 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nucleo_P87 PF07267.6 KII89937.1 - 3.5 6.2 3.7 5.1 5.6 2.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 APH PF01636.18 KII89938.1 - 0.091 12.4 1.9 0.7 9.5 0.7 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2262 PF10020.4 KII89939.1 - 0.15 12.2 1.4 0.18 12.0 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Chromo PF00385.19 KII89940.1 - 1.5e-11 43.7 0.2 1.8e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KII89940.1 - 0.055 13.1 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF3357 PF11837.3 KII89942.1 - 1.3 8.8 4.0 6.7 6.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Dimer_Tnp_hAT PF05699.9 KII89944.1 - 7.4e-14 51.1 0.1 8.5e-14 50.9 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ACC_epsilon PF13822.1 KII89946.1 - 0.026 14.8 1.9 0.039 14.3 1.3 1.3 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Transposase_21 PF02992.9 KII89951.1 - 3e-06 26.5 0.1 9e-06 24.9 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 Auto_anti-p27 PF06677.7 KII89951.1 - 0.019 14.7 2.4 2.7 7.8 0.1 3.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4218 PF13960.1 KII89951.1 - 0.051 13.0 0.1 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Asp PF00026.18 KII89952.1 - 1.8e-48 165.4 1.3 2.7e-48 164.8 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII89952.1 - 6.1e-09 36.0 0.8 6.1e-09 36.0 0.5 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII89952.1 - 0.00024 21.5 0.6 0.11 13.0 0.2 3.5 2 1 0 2 2 2 1 Aspartyl protease RasGAP PF00616.14 KII89953.1 - 1.1e-55 188.3 0.7 3.2e-54 183.5 0.0 2.8 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KII89953.1 - 2.7e-36 124.3 0.7 2.7e-36 124.3 0.5 2.2 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 KII89953.1 - 8.8 6.7 8.6 21 5.4 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Na_Ca_ex PF01699.19 KII89956.1 - 1.4e-42 144.6 38.3 7.4e-26 90.4 6.0 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MLANA PF14991.1 KII89956.1 - 1 9.4 5.1 0.15 12.0 0.3 2.0 2 0 0 2 2 2 0 Protein melan-A SGL PF08450.7 KII89957.1 - 0.0003 20.2 0.0 0.001 18.5 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KII89957.1 - 0.03 14.2 0.1 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Arylesterase Lactonase PF10282.4 KII89957.1 - 0.05 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller BRO1 PF03097.13 KII89959.1 - 3.3e-82 276.2 0.0 5.6e-82 275.4 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KII89959.1 - 1e-66 224.9 8.8 1.9e-66 224.0 6.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Ferritin PF00210.19 KII89959.1 - 0.75 9.5 5.8 0.57 9.9 0.6 2.6 2 0 0 2 2 2 0 Ferritin-like domain DnaJ PF00226.26 KII89961.1 - 6.2e-26 89.9 3.7 9.6e-26 89.3 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KII89961.1 - 2.6e-18 65.6 0.0 1.2e-16 60.4 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KII89961.1 - 1.2e-15 57.2 17.0 1.9e-15 56.6 11.8 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KII89961.1 - 0.0084 15.7 4.1 0.39 10.4 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KII89961.1 - 0.098 12.9 7.1 1.1 9.6 0.1 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar PADR1 PF08063.7 KII89961.1 - 0.56 9.6 9.4 0.46 9.9 0.1 2.9 2 1 1 3 3 3 0 PADR1 (NUC008) domain DZR PF12773.2 KII89961.1 - 0.82 9.5 11.1 63 3.5 8.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon PhzC-PhzF PF02567.11 KII89962.1 - 1.3e-41 142.7 0.0 1.5e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 KII89962.1 - 0.00025 19.9 0.0 0.009 14.8 0.0 2.1 2 0 0 2 2 2 2 Proline racemase Xpo1 PF08389.7 KII89963.1 - 2.9e-15 56.4 0.0 1.5e-14 54.1 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KII89963.1 - 0.00017 21.3 0.3 0.059 13.4 0.0 4.6 4 1 1 5 5 5 1 HEAT repeat MIT PF04212.13 KII89963.1 - 0.14 12.0 0.1 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Cullin PF00888.17 KII89964.1 - 7.6e-150 500.2 0.0 1e-149 499.8 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KII89964.1 - 2.6e-29 100.8 2.9 7.4e-29 99.3 2.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF479 PF04336.7 KII89964.1 - 0.021 14.9 0.0 0.51 10.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF479 Pyr_redox PF00070.22 KII89965.1 - 3.4e-11 43.4 0.1 9.9e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII89965.1 - 2.3e-09 37.4 0.0 0.022 14.6 0.1 4.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII89965.1 - 0.00034 19.6 0.2 0.36 9.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII89965.1 - 0.028 14.1 0.3 0.34 10.6 0.0 2.6 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KII89965.1 - 0.033 14.2 0.0 6.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KII89965.1 - 0.058 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KII89965.1 - 0.067 13.2 0.0 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.2 KII89966.1 - 4.1e-06 26.4 0.6 1.1e-05 25.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII89966.1 - 1.8e-05 24.2 0.5 4.6e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain DUF1490 PF07371.7 KII89967.1 - 0.75 9.7 6.1 0.25 11.3 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1490) DUF883 PF05957.8 KII89967.1 - 3.7 8.0 13.7 4.6 7.7 2.7 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Cellulase PF00150.13 KII89968.1 - 1e-14 54.4 2.1 2.5e-14 53.1 1.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Colipase PF01114.13 KII89970.1 - 0.04 13.4 1.4 0.096 12.1 1.0 1.6 1 0 0 1 1 1 0 Colipase, N-terminal domain Rubrerythrin PF02915.12 KII89972.1 - 0.011 16.0 1.5 0.024 14.9 1.0 1.6 1 0 0 1 1 1 0 Rubrerythrin PIN_2 PF10130.4 KII89972.1 - 0.058 13.4 1.1 0.11 12.4 0.7 1.4 1 0 0 1 1 1 0 PIN domain Peptidase_M57 PF12388.3 KII89973.1 - 0.068 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1183 PF06682.7 KII89974.1 - 3.5e-62 210.8 1.8 7.8e-62 209.7 1.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Pex14_N PF04695.8 KII89974.1 - 0.052 13.5 0.2 0.34 10.9 0.0 1.9 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OPT PF03169.10 KII89975.1 - 8.9e-140 467.0 20.4 1e-139 466.8 14.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3995 PF13160.1 KII89975.1 - 0.029 14.4 0.3 0.029 14.4 0.2 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF3995) Lysis_S PF04971.7 KII89975.1 - 0.27 10.9 6.8 3.2 7.4 0.2 3.3 3 0 0 3 3 3 0 Lysis protein S tRNA-synt_1g PF09334.6 KII89976.1 - 7.3e-129 429.8 0.0 9.2e-129 429.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 KII89976.1 - 2.1e-05 24.1 3.5 4.6e-05 22.9 2.4 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Anticodon_1 PF08264.8 KII89976.1 - 5.8e-05 22.8 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 KII89976.1 - 0.00029 19.0 0.0 0.003 15.6 0.0 2.5 4 0 0 4 4 4 1 tRNA synthetases class I (I, L, M and V) DUF1289 PF06945.8 KII89976.1 - 0.16 11.4 2.6 2.4 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) C1_1 PF00130.17 KII89976.1 - 0.46 10.2 2.1 1.1 9.0 1.4 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 KII89976.1 - 8.1 6.3 8.6 51 3.7 5.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon Pectate_lyase_3 PF12708.2 KII89977.1 - 3.4e-85 285.7 26.4 2.9e-70 236.9 7.2 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KII89977.1 - 5.2e-09 35.4 2.0 0.0034 16.7 0.1 3.4 2 1 1 3 3 3 2 N terminal extension of bacteriophage endosialidase Asp PF00026.18 KII89978.1 - 5.3e-49 167.1 17.6 1.1e-48 166.1 12.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII89978.1 - 8.7e-07 29.0 7.2 4e-05 23.6 3.1 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII89978.1 - 0.0025 18.2 5.5 0.12 12.8 0.9 2.8 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KII89978.1 - 0.048 13.2 0.5 0.99 8.9 0.3 2.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal RVP PF00077.15 KII89978.1 - 0.16 11.9 0.7 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease COX5B PF01215.14 KII89980.1 - 2.4e-41 140.6 0.0 2.8e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-RING_4 PF14570.1 KII89980.1 - 0.12 11.9 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Na_Ca_ex PF01699.19 KII89981.1 - 5.7e-30 103.7 28.9 3e-17 62.5 7.5 3.0 2 1 0 3 3 3 2 Sodium/calcium exchanger protein YWFCY PF14293.1 KII89981.1 - 0.018 14.8 0.1 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 YWFCY protein DUF3784 PF12650.2 KII89981.1 - 0.12 12.3 0.0 0.12 12.3 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF3784) PRK PF00485.13 KII89982.1 - 1.7e-47 161.4 0.0 2.5e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KII89982.1 - 4.3e-44 150.2 0.0 2.9e-43 147.5 0.0 2.0 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_33 PF13671.1 KII89982.1 - 2.8e-05 24.0 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII89982.1 - 9.9e-05 23.1 0.0 0.00047 20.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII89982.1 - 0.00018 21.7 0.0 0.00041 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KII89982.1 - 0.0093 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.15 KII89982.1 - 0.04 13.3 0.1 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase CPT PF07931.7 KII89982.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2392 PF10288.4 KII89983.1 - 2.8e-09 37.2 0.0 6.4e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) DUF2616 PF11077.3 KII89983.1 - 0.049 13.1 0.5 0.12 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-P11 PF03854.9 KII89983.1 - 0.44 10.0 5.1 1.4 8.4 0.0 3.2 3 0 0 3 3 3 0 P-11 zinc finger DZR PF12773.2 KII89983.1 - 3 7.7 10.6 10 6.0 1.0 3.1 2 1 0 2 2 2 0 Double zinc ribbon p450 PF00067.17 KII89984.1 - 9.3e-45 153.0 0.0 1.1e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YqjK PF13997.1 KII89984.1 - 0.65 10.2 7.4 0.29 11.3 0.1 3.2 3 0 0 3 3 3 0 YqjK-like protein Sugar_tr PF00083.19 KII89985.1 - 3.1e-117 391.9 25.5 3.7e-117 391.6 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII89985.1 - 1.5e-29 102.8 49.2 2.9e-19 68.9 11.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII89985.1 - 0.014 13.8 38.9 0.081 11.2 8.7 3.8 2 2 1 3 3 3 0 MFS/sugar transport protein Oxidored_FMN PF00724.15 KII89986.1 - 4.9e-71 239.4 0.0 6.2e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII89987.1 - 1.6e-69 234.5 0.0 2e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KII89987.1 - 0.04 12.7 0.0 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) UvrD_C PF13361.1 KII89988.1 - 4.4e-69 233.5 0.0 6.9e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KII89988.1 - 5.5e-65 219.7 0.0 9.3e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 KII89988.1 - 3e-14 52.5 0.3 1.6e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 KII89988.1 - 6.3e-13 48.7 0.0 2.2e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KII89988.1 - 8.7e-07 28.6 0.9 0.21 11.0 0.0 3.8 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KII89988.1 - 0.00026 20.6 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KII89988.1 - 0.00029 20.4 0.0 0.023 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain HSP20 PF00011.16 KII89990.1 - 6.2e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF2630 PF10944.3 KII89990.1 - 0.086 12.9 0.4 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Bud13 PF09736.4 KII89991.1 - 3.9e-47 160.1 12.3 3.9e-47 160.1 8.5 2.0 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Mit_ribos_Mrp51 PF11709.3 KII89991.1 - 0.0077 15.4 1.0 0.01 15.0 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FlaA PF04620.7 KII89992.1 - 0.006 16.0 0.1 21 4.4 0.0 3.3 3 0 0 3 3 3 3 Flagellar filament outer layer protein Flaa RNase_HII PF01351.13 KII89993.1 - 1e-43 149.2 0.0 2.5e-36 125.1 0.0 2.0 2 0 0 2 2 2 2 Ribonuclease HII NDUF_B12 PF08122.7 KII89994.1 - 0.48 10.1 4.8 8.9 6.1 0.0 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family NfeD PF01957.13 KII89994.1 - 0.76 9.8 5.3 0.48 10.5 1.4 2.1 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4231 PF14015.1 KII89994.1 - 0.92 9.5 12.5 1 9.3 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) PgaD PF13994.1 KII89994.1 - 1.2 8.6 5.2 0.22 10.9 0.8 1.9 2 0 0 2 2 2 0 PgaD-like protein PRA1 PF03208.14 KII89994.1 - 3.2 7.0 7.3 1.9 7.8 3.3 1.9 1 1 1 2 2 2 0 PRA1 family protein Vac14_Fig4_bd PF11916.3 KII89995.1 - 0.0033 16.6 0.8 0.05 12.7 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding DUF92 PF01940.11 KII89996.1 - 4.1e-58 196.2 10.9 5.3e-58 195.8 7.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 2H-phosphodiest PF08975.5 KII89997.1 - 0.032 13.9 0.0 0.086 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) GlyL_C PF12524.3 KII90003.1 - 2.9 7.8 8.7 0.31 10.9 0.7 2.7 2 1 0 2 2 2 0 dsDNA virus glycoprotein L C terminal TACC PF05010.9 KII90007.1 - 0.026 14.2 0.0 0.065 12.9 0.0 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) EF-hand_5 PF13202.1 KII90007.1 - 0.075 12.4 0.0 0.2 11.0 0.0 1.8 1 0 0 1 1 1 0 EF hand PfkB PF00294.19 KII90008.1 - 1.9e-12 46.9 0.0 5.9e-05 22.3 0.0 3.0 3 0 0 3 3 3 3 pfkB family carbohydrate kinase TPR_16 PF13432.1 KII90009.1 - 1.4e-14 54.2 8.4 3.7e-08 33.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII90009.1 - 1.7e-12 47.5 10.7 2.1e-06 27.9 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII90009.1 - 6.8e-11 41.6 0.9 0.0012 18.4 0.0 3.7 4 0 0 4 4 3 2 TPR repeat TPR_2 PF07719.12 KII90009.1 - 5.9e-09 35.1 5.1 0.33 10.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII90009.1 - 1.2e-08 34.1 1.8 1.2 8.8 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII90009.1 - 3.6e-08 33.3 15.9 0.098 13.3 0.1 6.5 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KII90009.1 - 8.2e-08 32.0 6.5 0.019 14.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII90009.1 - 2.1e-06 27.4 0.1 0.096 12.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII90009.1 - 0.00022 20.8 0.2 9.7 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KII90009.1 - 0.0012 18.6 0.8 0.036 13.9 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KII90009.1 - 0.0013 19.0 9.1 3.9 8.1 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII90009.1 - 0.0026 17.5 8.6 0.02 14.7 0.6 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat Pex26 PF07163.7 KII90009.1 - 0.0098 14.8 0.2 0.019 13.9 0.2 1.4 1 0 0 1 1 1 1 Pex26 protein MIT PF04212.13 KII90009.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 KII90009.1 - 0.082 13.3 1.5 0.33 11.5 0.1 3.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KII90009.1 - 0.11 12.2 0.4 93 3.1 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KII90009.1 - 0.15 12.2 0.3 0.98 9.6 0.0 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_10 PF13374.1 KII90009.1 - 1.9 8.5 4.1 11 6.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Svf1 PF08622.5 KII90011.1 - 3e-87 292.6 0.0 3.5e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Svf1-like DUF4454 PF14628.1 KII90011.1 - 0.089 12.4 0.1 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Peptidase_M48 PF01435.13 KII90012.1 - 4.4e-10 39.5 0.0 6.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 KII90012.1 - 0.16 12.0 0.2 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Sdh_cyt PF01127.17 KII90014.1 - 3.7 7.3 9.1 6 6.7 1.5 2.2 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Exosortase_EpsH PF09721.5 KII90014.1 - 3.7 6.6 14.4 25 3.9 10.0 2.0 1 1 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) Striatin PF08232.7 KII90015.1 - 9.7 6.5 11.1 4.1 7.7 0.1 3.9 4 0 0 4 4 4 0 Striatin family EF-hand_6 PF13405.1 KII90017.1 - 0.009 15.8 0.1 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KII90017.1 - 0.082 12.2 0.1 0.24 10.7 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 KII90017.1 - 0.092 12.0 0.3 0.38 10.1 0.0 2.3 2 0 0 2 2 2 0 EF hand DUF948 PF06103.6 KII90017.1 - 1.3 8.8 8.2 7 6.5 0.3 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF155 PF02582.9 KII90019.1 - 5.3e-42 143.6 0.0 6.6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2199 PF09965.4 KII90019.1 - 0.08 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) SART-1 PF03343.8 KII90021.1 - 2e-130 436.0 64.1 2e-130 436.0 44.5 1.9 2 0 0 2 2 2 2 SART-1 family ADH_zinc_N PF00107.21 KII90023.1 - 2.5e-19 69.1 0.0 4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII90023.1 - 8.8e-09 36.3 0.0 1.7e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.11 KII90023.1 - 0.0047 16.1 0.0 0.0073 15.5 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein ELFV_dehydrog PF00208.16 KII90023.1 - 0.05 13.1 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MIP PF00230.15 KII90024.1 - 8.3e-26 90.8 11.3 1.3e-25 90.2 7.8 1.3 1 0 0 1 1 1 1 Major intrinsic protein LsmAD PF06741.8 KII90025.1 - 2.7e-28 97.8 3.5 1.3e-27 95.6 0.2 2.4 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 KII90025.1 - 7.7e-07 28.9 0.1 2.1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Mad3_BUB1_I PF08311.7 KII90027.1 - 6.2e-34 116.5 0.9 1.1e-33 115.6 0.6 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KII90027.1 - 5.6e-13 48.6 0.0 1.6e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90027.1 - 0.00033 19.8 0.0 0.00056 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 KII90027.1 - 0.00084 19.1 0.0 0.0043 16.9 0.0 2.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 CNH PF00780.17 KII90029.1 - 2e-34 119.2 0.0 3e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KII90029.1 - 6.7e-33 114.0 0.2 1e-32 113.4 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KII90029.1 - 5.3e-07 29.6 0.0 1.9e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KII90029.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Lactonase PF10282.4 KII90030.1 - 1.6e-08 34.0 0.0 7.9e-06 25.1 0.0 2.8 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller PASTA PF03793.14 KII90030.1 - 0.0083 15.7 0.0 0.12 11.9 0.0 2.9 3 0 0 3 3 3 1 PASTA domain WD40 PF00400.27 KII90031.1 - 9.8e-48 158.4 5.7 2.1e-09 36.9 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 KII90031.1 - 6.5e-05 22.5 2.1 0.00079 18.9 1.3 2.8 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 KII90031.1 - 0.26 9.3 0.5 2.5 6.1 0.2 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KII90031.1 - 5.6 7.3 11.6 12 6.3 0.0 5.3 6 1 0 6 6 6 0 PQQ-like domain Helicase_C PF00271.26 KII90032.1 - 9.4e-13 47.8 0.0 2e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII90032.1 - 6.2e-11 42.0 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase EF-1_beta_acid PF10587.4 KII90035.1 - 1.4 9.1 5.9 3.1 8.0 4.1 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region SpoIISB_antitox PF14185.1 KII90038.1 - 0.12 12.1 0.6 0.88 9.3 0.1 2.2 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system zf-CCHC PF00098.18 KII90038.1 - 0.36 10.8 3.5 0.65 10.0 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KII90038.1 - 1.3 8.5 5.8 2.5 7.6 4.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Dimer_Tnp_hAT PF05699.9 KII90039.1 - 5e-07 29.2 0.1 2e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.10 KII90039.1 - 1.2e-06 28.0 0.6 2.2e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) CUE PF02845.11 KII90040.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 CUE domain Transposase_21 PF02992.9 KII90042.1 - 8.9e-08 31.4 0.0 1.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KII90042.1 - 7.4e-06 25.4 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Zn_Tnp_IS1595 PF12760.2 KII90042.1 - 0.0099 15.6 1.1 1.6 8.5 0.1 2.9 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KII90042.1 - 0.11 11.6 9.8 0.26 10.5 2.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KII90042.1 - 1.5 8.7 8.5 1.9 8.3 0.5 3.0 3 0 0 3 3 3 0 Double zinc ribbon HypA PF01155.14 KII90042.1 - 2 8.1 4.1 8.8 6.0 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KII90042.1 - 2.3 7.8 9.4 6.2 6.4 1.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain AA_permease_2 PF13520.1 KII90043.1 - 8.8e-56 189.2 41.7 1.1e-55 188.9 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII90043.1 - 5.9e-15 54.5 33.7 8.4e-15 54.0 23.4 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KII90043.1 - 6.5 6.6 9.2 0.63 9.9 0.1 3.4 3 0 0 3 3 3 0 Gram positive anchor WD40 PF00400.27 KII90045.1 - 3.9e-120 387.9 62.6 5.8e-14 51.3 0.8 12.7 13 0 0 13 13 12 11 WD domain, G-beta repeat DUF3312 PF11768.3 KII90045.1 - 6.9e-12 44.3 1.1 0.023 12.9 0.0 6.2 3 2 4 7 7 7 4 Protein of unknown function (DUF3312) PD40 PF07676.7 KII90045.1 - 1.2e-11 43.9 19.7 5.9 6.6 0.0 11.0 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat NACHT PF05729.7 KII90045.1 - 7.7e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII90045.1 - 6e-06 26.3 0.1 3e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KII90045.1 - 0.00024 21.2 0.0 0.0012 19.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII90045.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KII90045.1 - 0.0058 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain SidE PF12252.3 KII90045.1 - 0.012 12.9 0.3 0.017 12.4 0.2 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein NTPase_1 PF03266.10 KII90045.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 KII90045.1 - 0.016 16.0 0.1 0.065 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KII90045.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KII90045.1 - 0.13 12.5 0.3 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1258 PF06869.7 KII90045.1 - 0.58 9.2 8.5 22 4.0 0.0 4.3 2 2 3 5 5 5 0 Protein of unknown function (DUF1258) AAA_23 PF13476.1 KII90045.1 - 6.3 7.0 5.1 37 4.5 0.4 2.7 2 1 0 2 2 2 0 AAA domain Gp_dh_C PF02800.15 KII90052.1 - 3.7e-71 237.6 0.0 5e-71 237.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KII90052.1 - 2.7e-58 196.2 0.1 4.4e-58 195.5 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII90052.1 - 0.037 13.1 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 KII90052.1 - 0.075 12.9 1.4 0.23 11.3 0.4 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 KII90053.1 - 8.9e-25 87.1 28.3 2.8e-16 59.2 8.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YhhN PF07947.9 KII90054.1 - 0.0034 16.7 0.2 0.0037 16.6 0.2 1.1 1 0 0 1 1 1 1 YhhN-like protein Ldh_1_N PF00056.18 KII90055.1 - 3e-46 156.7 0.1 8.3e-46 155.3 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KII90055.1 - 2.7e-39 134.6 0.0 3.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KII90055.1 - 0.00054 18.7 0.0 0.00073 18.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KII90055.1 - 0.075 12.1 2.5 1 8.4 0.1 3.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AflR PF08493.5 KII90057.1 - 0.34 9.9 1.9 0.78 8.7 1.3 1.6 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF4218 PF13960.1 KII90058.1 - 5.3e-06 25.8 0.1 9.8e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CD99L2 PF12301.3 KII90060.1 - 0.1 12.2 5.3 0.17 11.5 3.7 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Fes1 PF08609.5 KII90063.1 - 3.5e-25 88.3 0.1 8.6e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KII90063.1 - 2.4e-06 27.7 0.4 0.0019 18.4 0.0 2.5 1 1 1 2 2 2 2 HEAT repeats DUF908 PF06012.7 KII90063.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HEAT_EZ PF13513.1 KII90063.1 - 0.034 14.6 0.2 7.3 7.2 0.0 3.2 3 1 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 KII90063.1 - 0.043 13.8 0.1 4.5 7.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat DUF258 PF03193.11 KII90065.1 - 0.2 10.8 0.1 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 WD40 PF00400.27 KII90067.1 - 4e-12 45.5 21.5 4.3e-06 26.3 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KII90067.1 - 0.025 14.0 0.0 1.5 8.3 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KII90067.1 - 0.099 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region DUF202 PF02656.10 KII90068.1 - 0.0031 17.6 5.5 0.0097 16.1 2.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF202) Hist_rich_Ca-bd PF10529.4 KII90068.1 - 0.5 10.4 4.6 0.93 9.5 3.2 1.4 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region DEAD PF00270.24 KII90069.1 - 3e-14 52.8 0.0 6.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII90069.1 - 6.6e-09 35.5 0.0 3.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII90069.1 - 0.022 14.5 0.0 0.33 10.7 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit EF1_GNE PF00736.14 KII90072.1 - 4.9e-31 106.2 2.3 9.6e-31 105.3 1.6 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KII90072.1 - 1.5e-12 47.4 9.7 1.5e-12 47.4 6.7 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KII90072.1 - 3e-05 24.4 0.0 6.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII90072.1 - 0.0016 18.4 0.4 0.0094 15.9 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII90072.1 - 0.047 13.5 0.1 1.4 8.9 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sigma70_r2 PF04542.9 KII90072.1 - 0.094 12.3 0.2 0.43 10.2 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 region 2 DNA_pol3_a_NII PF11490.3 KII90072.1 - 4.2 7.0 5.5 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TBX PF12598.3 KII90072.1 - 6.2 7.2 8.5 0.57 10.5 1.1 2.5 3 0 0 3 3 3 0 T-box transcription factor OapA_N PF08525.6 KII90075.1 - 0.94 9.3 0.1 0.94 9.3 0.1 2.5 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif F-box-like PF12937.2 KII90077.1 - 0.0093 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like VIGSSK PF14773.1 KII90080.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal PhnA_Zn_Ribbon PF08274.7 KII90081.1 - 0.53 10.1 3.7 3.9 7.3 0.8 2.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon WD40 PF00400.27 KII90082.1 - 2.3e-12 46.2 6.1 1.9e-07 30.6 0.5 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.20 KII90084.1 - 1.3e-06 27.7 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Chorion_2 PF03964.10 KII90084.1 - 6 7.4 7.8 7.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Chorion family 2 HLH PF00010.21 KII90086.1 - 4.7e-14 51.8 0.1 7.2e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M16 PF00675.15 KII90087.1 - 2.5e-23 82.4 0.1 5.3e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KII90087.1 - 0.011 15.3 0.0 0.053 13.1 0.0 2.0 1 1 0 1 1 1 0 Peptidase M16 inactive domain GATA PF00320.22 KII90088.1 - 6.9e-26 89.3 19.9 1.5e-15 56.1 2.4 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 KII90088.1 - 1.9e-10 40.1 0.6 3.8e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 KII90088.1 - 0.18 11.1 6.7 0.16 11.3 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 KII90088.1 - 0.87 9.5 5.8 8 6.5 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 KII90088.1 - 1.8 8.2 7.9 4.9 6.8 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zinc_ribbon_5 PF13719.1 KII90088.1 - 1.8 8.2 4.6 3.1 7.4 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KII90088.1 - 3.6 7.3 5.6 2.8 7.7 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 KII90088.1 - 7.1 6.5 10.3 94 2.9 7.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 KII90088.1 - 8.9 6.4 7.5 0.42 10.6 0.6 2.2 2 0 0 2 2 2 0 zinc-finger RRN7 PF11781.3 KII90088.1 - 9.2 5.8 10.8 0.33 10.4 0.4 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Glyco_hydro_1 PF00232.13 KII90091.1 - 1.9e-111 372.4 0.2 2.7e-111 371.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.13 KII90092.1 - 4.3e-109 364.7 0.2 6e-109 364.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 NST1 PF13945.1 KII90093.1 - 1.9e-57 194.4 0.0 1.9e-57 194.4 0.0 4.3 3 1 1 4 4 4 1 Salt tolerance down-regulator Utp14 PF04615.8 KII90093.1 - 0.0013 17.0 75.3 0.0013 17.0 52.2 2.5 2 0 0 2 2 2 1 Utp14 protein E1-E2_ATPase PF00122.15 KII90096.1 - 9e-25 87.0 0.0 9e-25 87.0 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KII90096.1 - 1.6e-18 67.9 0.0 1.5e-17 64.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII90096.1 - 3.2e-12 47.0 0.0 7.7e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII90096.1 - 2.1e-06 27.5 0.0 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KII90096.1 - 0.00019 21.1 0.0 0.00046 19.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KII90098.1 - 9.9e-15 54.3 0.0 1.3e-13 50.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90098.1 - 2.2e-06 26.9 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII90098.1 - 0.0024 16.9 0.1 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.21 KII90099.1 - 6.8e-26 90.3 0.8 1e-25 89.7 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII90099.1 - 2e-17 64.2 0.1 4.7e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90099.1 - 8.7e-09 35.1 0.0 2.4e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KII90099.1 - 0.0093 15.5 0.2 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KII90099.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-DHHC PF01529.15 KII90100.1 - 2.8e-34 117.9 2.5 2.8e-34 117.9 1.7 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase PocR PF10114.4 KII90100.1 - 0.9 8.6 4.3 1.5 7.9 3.0 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR ABA_GPCR PF12430.3 KII90101.1 - 7.1e-43 146.0 2.6 7.1e-43 146.0 1.8 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KII90101.1 - 6.9e-14 51.6 0.1 2.4e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) E1-E2_ATPase PF00122.15 KII90101.1 - 0.0038 16.2 0.2 0.022 13.8 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Adeno_GP19K PF04881.8 KII90101.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Adenovirus GP19K EF1G PF00647.14 KII90102.1 - 6.4e-43 144.8 0.1 1.3e-42 143.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 KII90102.1 - 6e-11 42.3 0.0 1.5e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KII90102.1 - 1.2e-10 41.4 0.1 6.2e-10 39.1 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII90102.1 - 1.1e-09 38.1 0.0 2.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII90102.1 - 2.7e-08 33.5 0.1 8.8e-08 31.9 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII90102.1 - 2.5e-06 27.8 0.0 7.9e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KII90102.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2360 PF10152.4 KII90102.1 - 0.03 14.6 2.9 0.048 13.9 2.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_5 PF12695.2 KII90102.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_60s PF00428.14 KII90102.1 - 9.5 6.6 13.1 22 5.5 9.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein NAD_binding_10 PF13460.1 KII90103.1 - 2.5e-28 99.3 0.1 3e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 KII90103.1 - 0.0054 16.5 0.4 0.78 9.5 0.0 2.4 2 1 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KII90103.1 - 0.084 13.1 0.0 0.24 11.7 0.0 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polyketide_cyc2 PF10604.4 KII90105.1 - 7.4e-09 35.8 0.2 1.2e-08 35.2 0.2 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KII90105.1 - 5e-06 26.5 0.3 7.2e-06 26.0 0.2 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport BP28CT PF08146.7 KII90106.1 - 3.3e-29 101.5 0.2 1.8e-28 99.1 0.1 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KII90106.1 - 1.9e-12 47.1 5.4 8.9e-12 45.0 0.8 4.3 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KII90106.1 - 1.3 9.2 10.2 0.19 11.8 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.20 KII90107.1 - 9.2e-37 126.5 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90107.1 - 5.6e-27 94.4 0.0 8e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII90107.1 - 2.6e-05 23.3 0.0 4.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 KII90107.1 - 4.4e-05 23.8 0.1 0.00023 21.4 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain PBD PF00786.23 KII90109.1 - 6.5e-07 29.6 0.2 0.0078 16.6 0.0 3.0 2 0 0 2 2 2 2 P21-Rho-binding domain Ribonuclease_T2 PF00445.13 KII90110.1 - 2.3e-37 128.4 0.1 3.2e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family BAG PF02179.11 KII90112.1 - 1.7e-05 24.8 0.1 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 BAG domain IQ PF00612.22 KII90112.1 - 0.0083 15.6 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif ADH_zinc_N PF00107.21 KII90113.1 - 2.6e-29 101.3 1.2 4.1e-29 100.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII90113.1 - 3.7e-16 60.1 0.3 8.1e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90113.1 - 8.7e-12 44.7 0.0 5.6e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KII90113.1 - 0.0022 17.6 0.1 0.0037 16.8 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KII90113.1 - 0.007 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HSP70 PF00012.15 KII90116.1 - 1.3e-82 277.6 2.9 1.3e-82 277.6 2.0 2.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KII90116.1 - 2.8e-06 26.1 0.2 7.3e-06 24.8 0.2 1.7 1 1 0 1 1 1 1 MreB/Mbl protein Membr_traf_MHD PF10540.4 KII90117.1 - 7.2e-20 71.1 0.0 2.1e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KII90117.1 - 5.6e-08 32.5 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.1 KII90118.1 - 5.7e-05 22.7 0.8 0.076 12.7 0.2 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KII90118.1 - 0.0027 17.2 0.3 1.4 8.6 0.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII90118.1 - 0.033 14.1 3.1 15 6.0 0.0 4.3 3 2 2 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KII90118.1 - 0.041 14.0 7.2 11 6.7 0.0 6.0 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KII90118.1 - 0.044 13.8 1.1 54 4.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat SET PF00856.23 KII90119.1 - 4.8e-21 75.7 0.3 4.8e-21 75.7 0.2 3.3 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KII90119.1 - 1.4e-16 60.1 11.4 4.8e-16 58.4 7.9 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain TFIIA PF03153.8 KII90119.1 - 0.036 13.9 12.7 0.055 13.3 8.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med26 PF08711.6 KII90119.1 - 0.15 11.5 2.5 0.53 9.8 0.0 2.9 3 0 0 3 3 3 0 TFIIS helical bundle-like domain R_equi_Vir PF05526.6 KII90119.1 - 2 7.9 4.1 3.8 7.1 2.9 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RNA_pol_I_A49 PF06870.7 KII90120.1 - 6.8e-85 284.9 0.1 7.6e-85 284.7 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor F-box-like PF12937.2 KII90123.1 - 2e-05 24.1 1.1 0.14 11.8 0.1 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KII90123.1 - 0.072 12.7 3.1 14 5.4 0.2 3.3 3 0 0 3 3 3 0 F-box domain zf-primase PF09329.6 KII90124.1 - 6.2e-12 44.9 0.9 1.1e-11 44.1 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger DUF1365 PF07103.6 KII90126.1 - 2.3e-29 102.1 0.0 3.9e-29 101.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) MFS_1 PF07690.11 KII90127.1 - 4e-36 124.4 32.1 4e-36 124.4 22.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 KII90128.1 - 1.4e-16 61.0 0.0 2.9e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII90128.1 - 2.3e-13 50.2 0.0 4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR PF05347.10 KII90129.1 - 2.2e-11 43.3 0.6 2.2e-11 43.3 0.4 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII90129.1 - 1.5e-09 37.8 0.3 2.9e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.4 KII90130.1 - 1.6e-24 85.7 26.9 1.5e-23 82.6 8.2 2.5 2 0 0 2 2 2 2 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 KII90130.1 - 6.8 5.0 25.0 9 4.6 17.3 1.1 1 0 0 1 1 1 0 Daxx Family V-SNARE PF05008.10 KII90132.1 - 0.00097 19.2 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus GTP_EFTU PF00009.22 KII90133.1 - 3.9e-37 127.5 0.0 6.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KII90133.1 - 6.7e-36 122.2 0.5 1.5e-35 121.0 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KII90133.1 - 4.5e-11 42.7 0.4 4.5e-11 42.7 0.3 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII90133.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PPR_2 PF13041.1 KII90134.1 - 1.8e-09 37.4 0.0 0.011 15.7 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 KII90134.1 - 9.4e-07 28.6 0.5 0.21 11.9 0.0 6.2 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 KII90134.1 - 0.0091 15.9 0.0 0.15 12.0 0.0 3.0 2 0 0 2 2 2 1 PPR repeat RRM_1 PF00076.17 KII90135.1 - 8.3e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII90135.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII90135.1 - 0.0004 20.2 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KII90135.1 - 0.63 9.7 35.6 0.91 9.2 24.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RINGv PF12906.2 KII90136.1 - 5e-07 29.6 6.6 9.3e-07 28.7 4.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KII90136.1 - 0.00032 20.4 6.1 0.00032 20.4 4.2 1.7 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 KII90136.1 - 0.0062 16.4 3.2 0.011 15.6 2.2 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 KII90136.1 - 0.011 15.8 3.3 0.011 15.8 2.3 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KII90136.1 - 0.23 11.5 4.0 0.65 10.0 2.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII90136.1 - 0.25 11.0 3.4 0.5 10.0 2.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_zinc_N PF00107.21 KII90137.1 - 1.2e-11 44.2 0.1 2.3e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90137.1 - 3.3e-10 39.6 0.4 3.6e-09 36.3 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII90137.1 - 0.043 14.7 0.0 0.084 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Helicase_RecD PF05127.9 KII90137.1 - 0.069 12.7 0.0 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Helicase F-box-like PF12937.2 KII90138.1 - 3.3e-07 29.9 3.0 3.3e-07 29.9 2.1 2.5 3 0 0 3 3 3 1 F-box-like KRAB PF01352.22 KII90138.1 - 0.14 11.6 0.2 0.38 10.2 0.2 1.7 1 0 0 1 1 1 0 KRAB box F-box PF00646.28 KII90138.1 - 3.2 7.5 7.4 1.1 9.0 0.4 3.0 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.11 KII90139.1 - 1.6e-34 119.2 39.6 2.2e-34 118.7 27.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KII90140.1 - 8.5e-35 120.0 37.5 1.3e-34 119.4 26.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily XdhC_C PF13478.1 KII90140.1 - 0.16 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Bap31 PF05529.7 KII90141.1 - 5.1e-53 179.4 4.1 6.5e-53 179.0 2.9 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Lge1 PF11488.3 KII90141.1 - 0.024 14.8 1.6 0.11 12.6 1.2 2.0 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DOG1 PF14144.1 KII90141.1 - 0.17 11.9 1.2 0.36 10.8 0.4 1.8 2 0 0 2 2 2 0 Seed dormancy control Cortexin PF11057.3 KII90141.1 - 0.23 11.0 1.4 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Cortexin of kidney DUF4446 PF14584.1 KII90141.1 - 0.48 10.2 3.4 0.34 10.7 0.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4094 PF13334.1 KII90141.1 - 1.3 9.4 5.6 2.5 8.5 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF2140 PF09911.4 KII90141.1 - 2.5 7.2 5.7 0.32 10.1 0.2 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) UCH PF00443.24 KII90142.1 - 5.5e-45 153.5 0.0 7.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII90142.1 - 4.6e-15 55.8 0.0 3.4e-14 52.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KII90142.1 - 8.6e-05 21.8 0.0 0.00022 20.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family RasGEF PF00617.14 KII90143.1 - 6.4e-25 87.9 0.0 1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII90143.1 - 3.5e-10 39.9 0.1 7.4e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SET PF00856.23 KII90144.1 - 3.5e-11 43.6 0.0 5.4e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.1 KII90144.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain Herpes_gp2 PF05955.6 KII90144.1 - 0.1 11.8 4.2 0.17 11.1 1.9 1.8 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 Lactonase PF10282.4 KII90145.1 - 9.5e-35 120.2 0.0 1.2e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KII90145.1 - 2.8e-05 23.6 0.0 7.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KII90145.1 - 0.0036 17.2 0.0 0.026 14.4 0.0 2.5 1 0 0 1 1 1 1 Arylesterase PD40 PF07676.7 KII90145.1 - 0.068 12.8 2.2 35 4.1 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ASF1_hist_chap PF04729.8 KII90146.1 - 5.4e-61 204.7 0.0 6.1e-61 204.5 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone p450 PF00067.17 KII90147.1 - 6e-59 199.7 0.0 1.4e-58 198.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UCH PF00443.24 KII90148.1 - 2.6e-09 36.6 0.0 3.4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase 5_3_exonuc PF01367.15 KII90148.1 - 0.00026 21.1 0.1 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UBA_4 PF14555.1 KII90148.1 - 0.00077 18.9 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 KII90148.1 - 0.042 13.4 2.5 6.6 6.5 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Osmo_CC PF08946.5 KII90148.1 - 8.8 6.4 6.8 3.9 7.5 0.8 2.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Fra10Ac1 PF09725.4 KII90149.1 - 1.7e-39 134.5 0.0 2.4e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF2039 PF10217.4 KII90149.1 - 0.063 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) 60KD_IMP PF02096.15 KII90151.1 - 9.1e-21 74.4 0.0 1.2e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein LELP1 PF15042.1 KII90151.1 - 2.1 8.5 15.9 0.64 10.2 8.8 1.7 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Na_H_Exchanger PF00999.16 KII90152.1 - 1.2e-66 224.7 35.2 1.6e-66 224.4 24.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_60s PF00428.14 KII90152.1 - 0.42 11.0 8.2 1.9 8.9 0.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein G-alpha PF00503.15 KII90153.1 - 6.4e-123 410.2 0.0 7.7e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII90153.1 - 8.2e-12 44.7 0.1 1.3e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 KII90153.1 - 0.028 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KII90153.1 - 0.038 13.0 0.1 0.098 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 KII90153.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirB8 PF04335.8 KII90155.1 - 0.81 9.2 3.1 1.1 8.8 2.2 1.2 1 0 0 1 1 1 0 VirB8 protein PIN_4 PF13638.1 KII90159.1 - 9.1e-13 48.4 0.3 5.3e-09 36.2 0.2 2.5 1 1 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 KII90159.1 - 2.9e-12 46.4 0.0 3.8e-11 42.7 0.0 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Alpha_kinase PF02816.13 KII90161.1 - 0.00015 21.4 0.8 0.06 13.0 0.0 2.1 2 0 0 2 2 2 2 Alpha-kinase family Alpha_kinase PF02816.13 KII90162.1 - 1.5e-16 60.6 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family PMT_C PF11647.3 KII90162.1 - 0.036 13.6 0.6 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 HTH_21 PF13276.1 KII90163.1 - 0.0088 16.0 0.5 0.06 13.3 0.0 2.5 3 0 0 3 3 3 1 HTH-like domain Acyl-CoA_dh_N PF02771.11 KII90163.1 - 0.072 13.6 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain p450 PF00067.17 KII90165.1 - 3.6e-62 210.3 0.0 3.6e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KII90166.1 - 8.4e-35 119.9 0.0 1.7e-34 118.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KII90166.1 - 3.5e-31 108.0 0.0 5.5e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KII90166.1 - 7.8e-10 38.5 0.0 2.8e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII90166.1 - 0.00043 20.3 0.0 0.0055 16.7 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII90166.1 - 0.0016 18.3 0.2 0.0079 16.1 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KII90166.1 - 0.0035 16.0 0.0 0.0068 15.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KII90166.1 - 0.007 16.0 0.0 0.031 13.9 0.0 2.1 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 KII90166.1 - 0.0086 16.3 0.1 0.032 14.4 0.1 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site Bromo_TP PF07524.8 KII90167.1 - 7.5e-09 35.2 0.7 8.9e-08 31.7 0.2 2.1 1 1 1 2 2 2 1 Bromodomain associated Histone PF00125.19 KII90167.1 - 0.04 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII90167.1 - 0.055 13.6 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore component CENP-S DUF159 PF02586.9 KII90168.1 - 3.8e-54 183.3 0.0 9.3e-54 182.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 DSPc PF00782.15 KII90170.1 - 1.6e-25 89.2 0.0 2.4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KII90170.1 - 3.9e-06 27.1 0.0 3.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KII90170.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KII90170.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 KII90170.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CUE PF02845.11 KII90171.1 - 4e-08 32.5 0.0 6.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain NmrA PF05368.8 KII90172.1 - 6.9e-42 143.2 0.1 1.2e-40 139.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KII90172.1 - 8.8e-15 55.1 0.8 5.5e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 KII90172.1 - 6.1e-07 29.5 4.9 0.015 15.1 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase 3Beta_HSD PF01073.14 KII90172.1 - 2.9e-05 22.9 0.1 4.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KII90172.1 - 5.8e-05 23.4 0.2 0.35 11.3 0.0 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KII90172.1 - 0.0003 19.8 0.9 0.0028 16.7 0.2 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 KII90172.1 - 0.0044 16.1 0.0 0.049 12.7 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KII90172.1 - 0.0075 16.5 0.4 0.054 13.7 0.1 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KII90172.1 - 0.014 14.3 0.6 2.6 6.8 0.0 2.8 4 0 0 4 4 4 0 RmlD substrate binding domain KR PF08659.5 KII90172.1 - 0.018 14.7 0.4 0.082 12.5 0.1 2.2 2 0 0 2 2 2 0 KR domain DXP_reductoisom PF02670.11 KII90172.1 - 0.077 13.5 0.2 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NmrA PF05368.8 KII90173.1 - 2.4e-40 138.2 0.0 2.8e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII90173.1 - 1e-11 45.1 1.2 1.9e-11 44.3 0.8 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII90173.1 - 2.8e-06 26.2 0.2 3.8e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII90173.1 - 1.2e-05 24.8 0.5 1.9e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KII90173.1 - 0.0015 18.4 0.3 0.0025 17.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KII90173.1 - 0.0016 17.4 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KII90173.1 - 0.0033 17.1 0.1 0.0062 16.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 KII90173.1 - 0.01 16.1 0.1 0.018 15.3 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 KII90173.1 - 0.029 14.9 0.2 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Peptidase_C5 PF00770.13 KII90174.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease CsbD PF05532.7 KII90175.1 - 0.0054 16.3 3.8 0.0087 15.7 2.4 1.5 1 1 0 1 1 1 1 CsbD-like GATase_4 PF13230.1 KII90176.1 - 4.5e-12 45.2 0.0 1.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KII90176.1 - 9.8e-09 35.2 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KII90176.1 - 0.025 13.3 0.1 0.033 12.8 0.1 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Rtt106 PF08512.7 KII90177.1 - 2.4e-15 56.2 0.0 5.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Herpes_UL49_2 PF04823.7 KII90177.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein LANC_like PF05147.8 KII90178.1 - 5.7e-32 110.6 0.0 3e-31 108.2 0.0 1.9 1 1 1 2 2 2 1 Lanthionine synthetase C-like protein DUF4419 PF14388.1 KII90179.1 - 1.8e-87 293.3 0.0 2.2e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.1 KII90180.1 - 0.051 12.7 0.0 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) WD40 PF00400.27 KII90181.1 - 7.8e-07 28.7 0.5 0.0083 15.9 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat UIM PF02809.15 KII90181.1 - 0.017 14.6 0.5 0.057 13.0 0.4 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif P16-Arc PF04699.9 KII90182.1 - 3.1e-49 166.9 0.0 3.6e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) TPR_11 PF13414.1 KII90183.1 - 1.7e-12 46.7 0.6 1.3e-11 43.9 0.1 2.3 2 0 0 2 2 2 1 TPR repeat DUF4470 PF14737.1 KII90183.1 - 8.4e-12 44.7 0.0 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_16 PF13432.1 KII90183.1 - 6.9e-06 26.5 0.3 0.0051 17.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII90183.1 - 6.6e-05 22.3 0.0 0.0022 17.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII90183.1 - 0.00048 19.8 0.7 0.019 14.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII90183.1 - 0.013 16.0 0.5 3.8 8.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.17 KII90185.1 - 1.5e-25 89.9 0.0 3.4e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase SWIB PF02201.13 KII90186.1 - 6.6e-16 57.7 0.0 1.8e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain PPP1R35_C PF15503.1 KII90186.1 - 0.15 11.5 1.1 0.23 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus BAR PF03114.13 KII90187.1 - 5.4e-35 120.9 14.3 7.4e-35 120.5 9.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KII90187.1 - 9.5e-14 50.5 0.4 2.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KII90187.1 - 2.3e-12 46.2 0.2 5.1e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII90187.1 - 5.9e-10 38.4 0.0 1.3e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Filament PF00038.16 KII90187.1 - 0.00022 20.8 13.1 0.00041 19.9 9.1 1.3 1 0 0 1 1 1 1 Intermediate filament protein FAM92 PF06730.6 KII90187.1 - 0.00033 20.0 4.2 0.00063 19.1 2.9 1.4 1 0 0 1 1 1 1 FAM92 protein LicD PF04991.8 KII90187.1 - 0.021 14.9 0.4 0.038 14.1 0.3 1.5 1 0 0 1 1 1 0 LicD family Spc7 PF08317.6 KII90187.1 - 0.035 12.7 10.9 0.07 11.7 7.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF883 PF05957.8 KII90187.1 - 1.9 8.9 6.1 1.7 9.0 2.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.14 KII90187.1 - 3.5 5.3 9.1 4.7 4.9 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_TM PF12794.2 KII90187.1 - 4 5.9 5.0 6.5 5.2 3.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 APG6 PF04111.7 KII90187.1 - 5.5 5.9 14.7 12 4.8 10.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KII90187.1 - 6.6 6.2 14.4 0.81 9.2 6.1 2.0 2 0 0 2 2 2 0 IncA protein SNase PF00565.12 KII90188.1 - 1.2e-19 70.5 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue FAD_binding_1 PF00667.15 KII90191.1 - 1.8e-36 125.6 0.0 2.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KII90191.1 - 1.3e-25 90.1 0.0 2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KII90191.1 - 5.9e-12 46.1 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1944 PF09175.5 KII90193.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Glyco_hydro_3 PF00933.16 KII90196.1 - 1.2e-82 277.3 0.0 4.8e-82 275.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII90196.1 - 5.4e-60 202.7 0.1 1.3e-59 201.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII90196.1 - 3.9e-16 58.7 0.0 7.2e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2387 PF09526.5 KII90198.1 - 0.019 14.8 0.8 0.03 14.2 0.1 1.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) FYDLN_acid PF09538.5 KII90198.1 - 0.041 14.4 4.2 0.057 14.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.1 KII90199.1 - 0.023 15.0 0.3 0.023 15.0 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Lipl32 PF12103.3 KII90199.1 - 0.12 11.8 0.5 0.21 11.0 0.3 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order LRR_8 PF13855.1 KII90201.1 - 0.0026 17.4 0.2 9.5 6.0 0.0 4.0 4 0 0 4 4 4 2 Leucine rich repeat RRM_1 PF00076.17 KII90202.1 - 8e-28 95.8 0.2 2.4e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII90202.1 - 2.3e-23 81.9 0.1 7.9e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII90202.1 - 1.3e-10 40.9 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 KII90202.1 - 0.89 10.0 36.9 1.8 9.0 25.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family ABC1 PF03109.11 KII90203.1 - 4.6e-26 91.1 0.0 7.6e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family YihI PF04220.7 KII90204.1 - 0.0016 17.7 0.6 0.0027 17.0 0.4 1.3 1 0 0 1 1 1 1 Der GTPase activator (YihI) PEMT PF04191.8 KII90205.1 - 2.8e-30 104.5 3.6 4.9e-30 103.7 2.1 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase LRR_8 PF13855.1 KII90206.1 - 0.041 13.6 0.0 1.2 8.9 0.0 3.2 4 1 0 4 4 4 0 Leucine rich repeat UQ_con PF00179.21 KII90207.1 - 1.9e-32 111.6 0.0 2.5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.19 KII90209.1 - 8.2e-101 337.7 20.6 9.4e-101 337.5 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90209.1 - 2.9e-26 92.0 27.4 4.9e-18 64.9 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KII90209.1 - 1.5e-06 26.5 1.1 2.8e-06 25.6 0.8 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family OTU PF02338.14 KII90210.1 - 6e-16 59.1 0.0 1.1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KII90210.1 - 0.083 12.2 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain F-box-like PF12937.2 KII90211.1 - 0.03 14.0 0.0 0.068 12.9 0.0 1.7 1 1 0 1 1 1 0 F-box-like DUF3678 PF12435.3 KII90211.1 - 1.2 8.7 7.6 4.9 6.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) adh_short PF00106.20 KII90212.1 - 1.5e-27 96.5 0.5 2.1e-27 96.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII90212.1 - 7.5e-17 61.8 0.0 9.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII90212.1 - 1.4e-09 37.9 0.1 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KII90212.1 - 3.6e-08 32.9 0.0 5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KII90212.1 - 3.4e-05 23.9 0.3 6.3e-05 23.0 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII90212.1 - 0.091 12.1 0.1 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SNF2_N PF00176.18 KII90213.1 - 4.5e-62 209.5 0.0 6.2e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII90213.1 - 4.4e-07 29.6 0.0 9.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII90213.1 - 5.2e-07 29.6 0.0 9.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KII90213.1 - 6.5e-05 22.4 1.6 0.00013 21.5 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII90213.1 - 7.5e-05 22.3 1.1 0.00014 21.5 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII90213.1 - 0.00013 21.7 1.4 0.00025 20.7 1.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KII90213.1 - 0.00021 20.9 0.5 0.00047 19.8 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KII90213.1 - 0.00029 20.7 2.3 0.00057 19.8 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII90213.1 - 0.0014 18.4 2.8 0.0026 17.5 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KII90213.1 - 0.0032 16.9 1.5 0.0073 15.8 1.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 KII90213.1 - 0.0056 16.3 1.1 0.01 15.4 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2141 PF09912.4 KII90214.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Ras PF00071.17 KII90216.1 - 2.4e-35 121.3 0.0 3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII90216.1 - 1.3e-11 45.0 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KII90216.1 - 1.2e-07 31.1 0.1 5.4e-06 25.7 0.1 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KII90216.1 - 4.9e-06 26.4 0.0 6.4e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KII90216.1 - 0.00011 21.6 0.0 0.02 14.3 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KII90216.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.5 1 1 1 2 2 2 1 AAA domain Arf PF00025.16 KII90216.1 - 0.0075 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 KII90216.1 - 0.015 15.4 0.0 0.23 11.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KII90216.1 - 0.14 11.6 0.0 0.89 9.0 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Acyl-thio_N PF12590.3 KII90217.1 - 0.081 13.3 0.4 0.15 12.4 0.3 1.4 1 0 0 1 1 1 0 Acyl-ATP thioesterase Bac_rhamnosid PF05592.6 KII90218.1 - 1.8e-28 99.0 0.2 1.4e-27 96.1 0.3 2.2 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KII90218.1 - 0.0036 16.0 0.4 0.0056 15.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KII90218.1 - 0.02 13.5 0.1 0.043 12.5 0.1 1.6 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KII90218.1 - 0.15 10.7 0.1 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 Trehalase F-box-like PF12937.2 KII90221.1 - 1.3e-06 28.0 1.2 2.3e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like IMP_cyclohyd PF07826.6 KII90221.1 - 0.053 12.8 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Macro PF01661.16 KII90222.1 - 2.3e-39 133.9 0.1 3.2e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 Macro domain DUF1995 PF09353.5 KII90222.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) PigN PF04987.9 KII90223.1 - 5.3e-109 364.8 34.1 6.6e-109 364.4 23.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KII90223.1 - 1.2e-09 38.0 0.1 4.4e-07 29.5 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KII90223.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KII90223.1 - 0.014 14.6 0.1 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Sulfatase Peroxidase_2 PF01328.12 KII90224.1 - 1.7e-21 76.2 0.0 2.8e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Peroxidase, family 2 DUF1687 PF07955.6 KII90225.1 - 4.5e-11 42.8 0.0 5.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Amino_oxidase PF01593.19 KII90226.1 - 4.1e-34 118.4 0.1 3.8e-33 115.2 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII90226.1 - 1e-09 38.2 0.0 3.5e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII90226.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KII90226.1 - 0.00047 19.3 0.5 0.00047 19.3 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KII90226.1 - 0.011 14.2 0.3 0.019 13.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KII90226.1 - 0.12 11.5 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF3824 PF12868.2 KII90227.1 - 1.5e-05 25.9 2.9 4.4e-05 24.4 2.0 1.8 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) EAP30 PF04157.11 KII90228.1 - 1.3e-31 109.5 0.0 1.8e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KII90228.1 - 2.8e-21 75.1 0.0 4.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KII90228.1 - 0.0034 16.4 12.4 0.12 11.5 1.0 2.7 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KII90228.1 - 0.0043 16.8 5.2 0.13 12.1 4.1 2.3 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 KII90228.1 - 0.41 9.9 9.8 0.16 11.2 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 KII90228.1 - 0.86 9.2 5.6 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Mito_carr PF00153.22 KII90229.1 - 2.4e-56 187.4 1.5 2.9e-19 68.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.7 KII90229.1 - 1.6 9.0 5.3 1 9.6 0.1 3.2 4 0 0 4 4 4 0 The GLUG motif SRP9-21 PF05486.7 KII90230.1 - 1.2e-16 60.1 0.7 1.5e-16 59.8 0.5 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.12 KII90230.1 - 0.13 11.9 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DEAD PF00270.24 KII90231.1 - 3.1e-09 36.5 0.0 5.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII90231.1 - 0.016 15.0 0.1 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Mucin PF01456.12 KII90233.1 - 0.0085 15.8 11.3 0.0085 15.8 7.8 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF1628 PF07790.6 KII90233.1 - 0.03 15.0 1.2 0.082 13.6 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) SpoIIIAH PF12685.2 KII90233.1 - 0.037 13.5 0.4 0.054 12.9 0.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2611 PF11022.3 KII90233.1 - 0.057 13.5 2.5 0.085 12.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2611) Shisa PF13908.1 KII90233.1 - 0.062 13.4 1.7 0.069 13.3 0.3 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SOG2 PF10428.4 KII90233.1 - 0.64 8.6 5.2 0.82 8.2 3.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein STE PF02200.11 KII90235.1 - 2.2e-36 124.3 0.0 3.8e-36 123.5 0.0 1.4 1 1 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KII90236.1 - 4.9e-15 54.8 10.7 1e-07 31.8 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII90236.1 - 2.9e-14 52.2 10.4 6e-07 29.3 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII90236.1 - 5.4e-10 39.0 15.8 2.3e-08 33.9 3.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KII90236.1 - 1.7e-06 27.9 0.7 0.02 15.0 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KII90236.1 - 5.8e-06 26.0 0.1 5.8e-06 26.0 0.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 KII90236.1 - 4.3e-05 23.5 1.8 0.046 13.9 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 KII90236.1 - 0.0008 19.1 5.5 0.069 12.9 0.1 2.1 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 KII90236.1 - 0.0027 17.8 0.7 0.23 11.5 0.0 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KII90236.1 - 0.0059 16.6 2.1 0.012 15.6 1.5 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KII90236.1 - 0.028 13.9 0.3 0.95 9.0 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-FPG_IleRS PF06827.9 KII90236.1 - 0.035 13.7 1.0 0.41 10.3 0.3 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS GAGA PF09237.6 KII90236.1 - 0.035 13.7 4.9 0.55 9.8 0.7 2.1 1 1 1 2 2 2 0 GAGA factor zf-TRAF PF02176.13 KII90236.1 - 0.042 14.2 1.8 0.073 13.4 1.3 1.4 1 1 0 1 1 1 0 TRAF-type zinc finger Ogr_Delta PF04606.7 KII90236.1 - 0.064 12.9 0.5 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.1 KII90236.1 - 0.1 12.2 5.2 2 8.1 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KII90236.1 - 0.15 12.0 0.3 0.15 12.0 0.2 1.6 2 0 0 2 2 1 0 zinc-finger Prok-RING_4 PF14447.1 KII90236.1 - 0.15 11.5 1.8 0.72 9.4 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Transpos_assoc PF13963.1 KII90236.1 - 0.17 11.8 3.1 4 7.4 0.8 2.0 1 1 1 2 2 2 0 Transposase-associated domain Elf1 PF05129.8 KII90236.1 - 0.36 10.5 3.4 0.2 11.3 1.0 1.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Phosphorylase PF00343.15 KII90237.1 - 3.9e-300 996.9 0.0 4.6e-300 996.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1708 PF08101.6 KII90238.1 - 3.5e-16 59.0 0.0 6.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KII90238.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 RhoGAP domain Sugar_tr PF00083.19 KII90241.1 - 8.7e-78 261.8 19.2 1.1e-77 261.6 13.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90241.1 - 1.6e-17 63.2 34.2 1.6e-09 37.0 7.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KII90241.1 - 1.7 8.6 7.3 0.54 10.3 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1228) NAD_binding_4 PF07993.7 KII90242.1 - 1.7e-34 118.9 0.0 2.5e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII90242.1 - 3.2e-31 108.1 0.0 7.8e-30 103.5 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KII90242.1 - 2.5e-09 36.9 0.0 4.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KII90242.1 - 2.1e-05 24.5 0.0 8.4e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KII90242.1 - 6.8e-05 21.7 0.0 0.00017 20.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KII90242.1 - 0.00076 19.1 0.0 0.0027 17.3 0.0 2.0 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 KII90242.1 - 0.0031 17.7 0.1 0.014 15.6 0.1 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KII90242.1 - 0.074 11.9 0.0 0.15 10.9 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_5 PF12695.2 KII90242.1 - 0.082 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Semialdhyde_dh PF01118.19 KII90242.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 KII90244.1 - 2.7e-09 36.5 0.0 2.7e-08 33.3 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90244.1 - 0.0077 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Statherin PF03875.8 KII90244.1 - 0.16 11.8 4.0 0.9 9.4 0.2 2.9 2 0 0 2 2 2 0 Statherin MFS_1 PF07690.11 KII90245.1 - 1.9e-23 82.7 58.8 1.7e-19 69.7 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII90245.1 - 0.00098 17.6 23.7 0.0018 16.7 13.3 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 KII90245.1 - 1.8 8.6 20.3 0.46 10.5 0.2 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1228) AMP-binding PF00501.23 KII90246.1 - 8e-81 271.5 0.1 1.3e-80 270.9 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme His_biosynth PF00977.16 KII90246.1 - 0.088 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein PhoU PF01895.14 KII90247.1 - 0.034 14.5 1.1 0.061 13.7 0.4 1.8 1 1 1 2 2 2 0 PhoU domain Syntaxin_2 PF14523.1 KII90247.1 - 0.035 14.1 1.0 0.65 10.0 0.1 2.2 1 1 1 2 2 2 0 Syntaxin-like protein GCIP PF13324.1 KII90247.1 - 0.16 11.1 1.8 3.7 6.6 0.3 2.2 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting RPW8 PF05659.6 KII90247.1 - 0.17 11.4 1.6 0.19 11.2 0.2 1.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GldM_N PF12081.3 KII90247.1 - 0.23 10.9 1.8 2.6 7.5 0.1 2.2 2 0 0 2 2 2 0 GldM N-terminal domain RRN3 PF05327.6 KII90247.1 - 0.89 7.5 2.3 0.8 7.7 0.9 1.3 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Taxilin PF09728.4 KII90247.1 - 2.2 7.3 6.7 1.1 8.2 1.3 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Transformer PF06495.6 KII90248.1 - 0.025 14.4 9.2 0.029 14.2 6.4 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Secretin_N_2 PF07655.8 KII90248.1 - 0.13 12.6 1.1 0.36 11.2 0.7 1.9 1 1 0 1 1 1 0 Secretin N-terminal domain Peptidase_A21 PF03566.8 KII90248.1 - 3.2 5.7 4.7 3.2 5.7 3.2 1.0 1 0 0 1 1 1 0 Peptidase family A21 Sorb PF02208.11 KII90251.1 - 0.78 9.1 9.9 3.9 6.9 0.2 3.9 3 1 0 3 3 3 0 Sorbin homologous domain Ribonuc_red_2_N PF08471.5 KII90253.1 - 0.00078 19.4 0.1 2.2 8.3 0.0 4.3 1 1 3 4 4 4 2 Class II vitamin B12-dependent ribonucleotide reductase DUF382 PF04037.8 KII90253.1 - 0.047 13.5 0.2 16 5.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF382) Lipase_GDSL_2 PF13472.1 KII90254.1 - 2.8e-12 47.1 2.0 5.2e-12 46.2 1.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII90254.1 - 0.00014 21.7 3.1 0.0019 18.0 2.2 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KII90254.1 - 0.0021 17.8 0.0 0.013 15.2 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 KII90256.1 - 5.9e-23 81.1 51.5 2.7e-14 52.6 21.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII90256.1 - 5.3e-22 78.0 21.2 1.3e-21 76.7 14.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4400 PF14348.1 KII90257.1 - 5.6 6.2 13.4 1.3 8.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Prefoldin PF02996.12 KII90258.1 - 5e-25 87.4 0.2 8e-24 83.5 0.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 KII90258.1 - 0.16 12.3 1.4 8.2 6.9 0.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RRM_1 PF00076.17 KII90259.1 - 7e-72 237.0 0.0 5.8e-17 61.0 0.0 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII90259.1 - 1.1e-64 214.3 0.0 6e-14 51.7 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII90259.1 - 1.6e-28 98.3 0.0 2.2e-06 27.4 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII90259.1 - 0.00011 21.9 0.6 0.6 9.9 0.0 4.4 3 1 1 4 4 4 1 RNA binding motif Limkain-b1 PF11608.3 KII90259.1 - 0.00012 21.7 0.0 0.73 9.6 0.0 4.8 4 1 0 4 4 4 1 Limkain b1 RRM_2 PF04059.7 KII90259.1 - 0.0057 16.6 0.0 5 7.1 0.0 3.8 4 0 0 4 4 4 1 RNA recognition motif 2 GMC_oxred_N PF00732.14 KII90260.1 - 1.5e-52 178.6 0.0 2.3e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII90260.1 - 5.5e-32 111.0 0.0 1.1e-31 110.0 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KII90260.1 - 0.0034 16.3 0.1 0.0048 15.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DUF373 PF04123.8 KII90261.1 - 0.47 9.4 2.2 0.48 9.4 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ank_5 PF13857.1 KII90262.1 - 1.3e-07 31.6 0.7 0.00042 20.4 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KII90262.1 - 7.7e-06 26.1 0.0 0.029 14.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII90262.1 - 0.00025 20.6 3.0 0.081 12.7 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KII90262.1 - 0.11 12.7 0.3 2.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Velvet PF11754.3 KII90263.1 - 3.1e-46 157.5 0.1 1.4e-36 125.9 0.0 2.3 2 0 0 2 2 2 2 Velvet factor Patatin PF01734.17 KII90267.1 - 3.2e-22 79.4 0.0 5.8e-22 78.6 0.0 1.4 1 1 0 1 1 1 1 Patatin-like phospholipase CARM1 PF11531.3 KII90267.1 - 0.064 12.9 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal TPR_10 PF13374.1 KII90268.1 - 4.5e-140 452.2 16.8 1.3e-12 47.2 0.3 17.1 17 0 0 17 17 17 15 Tetratricopeptide repeat TPR_12 PF13424.1 KII90268.1 - 2e-116 380.1 52.7 4.1e-15 55.4 0.7 13.3 1 1 15 16 16 16 16 Tetratricopeptide repeat TPR_7 PF13176.1 KII90268.1 - 5.4e-38 125.7 25.6 0.024 14.3 0.1 14.7 15 0 0 15 15 14 11 Tetratricopeptide repeat TPR_17 PF13431.1 KII90268.1 - 1.7e-31 105.7 25.3 0.072 13.3 0.0 14.6 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_1 PF00515.23 KII90268.1 - 1.8e-31 106.4 37.1 0.046 13.3 0.0 15.6 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_4 PF07721.9 KII90268.1 - 3.8e-30 101.1 1.1 0.055 13.9 0.1 14.3 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 KII90268.1 - 7.8e-29 99.8 21.1 0.14 12.5 0.1 13.9 9 4 4 14 14 14 7 Tetratricopeptide repeat TPR_16 PF13432.1 KII90268.1 - 6.3e-26 90.4 1.4 0.021 15.5 0.0 10.9 6 2 6 12 12 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 KII90268.1 - 1.9e-22 77.3 33.6 0.83 9.7 0.0 15.1 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_11 PF13414.1 KII90268.1 - 3.1e-15 55.5 20.2 0.013 15.0 0.1 11.2 6 3 6 12 12 12 6 TPR repeat TPR_14 PF13428.1 KII90268.1 - 6.7e-13 48.0 24.7 4 8.3 0.0 14.0 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII90268.1 - 3.8e-11 41.9 37.2 1.8 8.5 0.1 14.0 15 0 0 15 15 14 3 Tetratricopeptide repeat Apc3 PF12895.2 KII90268.1 - 3.7e-07 30.1 10.2 0.071 13.2 0.0 7.6 3 3 6 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF814 PF05670.8 KII90268.1 - 2.3e-05 24.1 3.3 5.3 7.0 0.0 8.0 4 3 6 10 10 10 1 Domain of unknown function (DUF814) TPR_20 PF14561.1 KII90268.1 - 5.7e-05 23.1 21.6 7.2 6.8 0.0 9.7 4 2 7 12 12 11 0 Tetratricopeptide repeat DUF4074 PF13293.1 KII90268.1 - 0.0013 18.8 16.0 7.7 6.8 0.0 9.2 11 0 0 11 11 9 0 Domain of unknown function (DUF4074) Rab5-bind PF09311.6 KII90268.1 - 0.0054 16.6 22.4 0.56 10.0 0.8 8.2 3 2 5 9 9 9 1 Rabaptin-like protein PPR PF01535.15 KII90268.1 - 0.017 15.0 17.3 36 4.6 0.0 10.6 16 0 0 16 16 11 0 PPR repeat RHS_repeat PF05593.9 KII90268.1 - 0.031 14.4 0.7 57 4.0 0.0 4.7 5 0 0 5 5 4 0 RHS Repeat TPR_3 PF07720.7 KII90268.1 - 0.035 13.9 24.6 0.8 9.5 0.0 9.5 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII90268.1 - 1.4 9.5 37.5 17 6.1 0.1 10.9 12 0 0 12 12 11 0 Tetratricopeptide repeat DUF1897 PF09005.5 KII90268.1 - 2.6 7.5 5.6 50 3.4 0.0 5.3 8 0 0 8 8 6 0 Domain of unknown function (DUF1897) DUF3353 PF11833.3 KII90270.1 - 0.054 12.9 0.1 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DAHP_synth_1 PF00793.15 KII90273.1 - 5.7e-79 264.6 0.0 4.3e-78 261.7 0.0 2.1 1 1 0 1 1 1 1 DAHP synthetase I family Patatin PF01734.17 KII90274.1 - 3.1e-24 86.0 0.0 4.6e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 KII90275.1 - 1.9e-28 99.7 0.0 3.1e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase PIH1 PF08190.7 KII90276.1 - 1.9e-24 86.7 0.0 4.6e-22 78.9 0.0 2.8 2 1 0 2 2 2 2 pre-RNA processing PIH1/Nop17 Ad_cyc_g-alpha PF08509.6 KII90276.1 - 0.067 12.5 0.4 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain LIM PF00412.17 KII90277.1 - 1.5e-26 92.2 19.4 1.9e-14 53.4 3.2 2.2 2 0 0 2 2 2 2 LIM domain DUF3039 PF11238.3 KII90277.1 - 0.75 9.2 4.1 11 5.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-DNA_Pol PF08996.5 KII90277.1 - 1.1 8.6 6.7 0.52 9.6 0.7 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF678 PF05077.7 KII90277.1 - 4.4 7.3 11.3 1.1 9.2 0.4 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF678) DUF1720 PF08226.6 KII90277.1 - 7.8 6.6 12.4 19 5.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1720) eIF-5a PF01287.15 KII90278.1 - 1.8e-27 95.0 0.7 2.6e-27 94.5 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KII90278.1 - 2.7e-05 23.7 0.8 5.8e-05 22.6 0.6 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KII90278.1 - 0.0051 16.6 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Lipase_3 PF01764.20 KII90280.1 - 4.6e-34 117.0 0.0 7.1e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) zf-RanBP PF00641.13 KII90281.1 - 0.00056 18.9 14.9 0.0038 16.3 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AAA_12 PF13087.1 KII90282.1 - 3.3e-56 189.8 0.0 4.6e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII90282.1 - 6.6e-50 169.8 0.0 9e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII90282.1 - 5.8e-12 45.1 0.4 3.2e-11 42.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KII90282.1 - 9.8e-10 38.3 0.2 2.1e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 KII90282.1 - 9.1e-06 25.1 0.1 1.9e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KII90282.1 - 0.00012 21.6 0.1 4.4 6.7 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KII90282.1 - 0.027 14.4 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KII90282.1 - 0.039 14.1 0.1 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KII90282.1 - 0.082 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 KII90282.1 - 0.17 10.8 1.6 1.6 7.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) tRNA-synt_1d PF00750.14 KII90282.1 - 0.27 10.0 0.0 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) RVT_1 PF00078.22 KII90283.1 - 3.5e-06 26.5 0.0 6.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 KII90283.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Laminin_EGF PF00053.19 KII90284.1 - 2.1 8.3 6.9 3.7 7.5 4.8 1.4 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) SAP PF02037.22 KII90285.1 - 0.047 13.2 0.1 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 SAP domain Rft-1 PF04506.8 KII90286.1 - 2.9e-80 270.2 0.1 6.2e-80 269.1 0.0 1.5 2 0 0 2 2 2 1 Rft protein Syja_N PF02383.13 KII90287.1 - 1.8e-87 293.1 0.1 2.7e-87 292.4 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain KAR9 PF08580.5 KII90288.1 - 2.9 6.0 3.9 4 5.6 2.7 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SR-25 PF10500.4 KII90292.1 - 0.0031 17.0 18.4 0.0063 16.0 12.7 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein YL1 PF05764.8 KII90292.1 - 0.27 10.7 27.0 0.059 12.9 16.3 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Dsh_C PF12316.3 KII90292.1 - 0.3 11.1 8.9 0.043 13.9 3.4 1.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2201_N PF13203.1 KII90292.1 - 0.44 9.6 8.2 0.64 9.1 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 KII90292.1 - 1.5 8.6 13.3 2.3 8.0 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cas_Cas6 PF01881.11 KII90293.1 - 0.031 14.4 0.0 0.041 14.1 0.0 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Asp_protease PF09668.5 KII90293.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 1 1 2 2 2 0 Aspartyl protease DDE_1 PF03184.14 KII90298.1 - 7.9e-05 21.8 0.0 9.3e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KII90298.1 - 0.0059 16.3 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3508 PF12018.3 KII90299.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) PT PF04886.7 KII90301.1 - 5.5e-10 38.3 30.2 1.9e-07 30.3 9.0 4.1 3 1 1 4 4 4 2 PT repeat Rz1 PF06085.6 KII90302.1 - 0.5 9.8 5.8 0.4 10.1 1.5 2.6 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor UBN2_2 PF14227.1 KII90306.1 - 7.6e-11 41.6 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII90306.1 - 4.1e-08 33.0 0.0 5.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII90306.1 - 0.024 14.5 5.7 0.036 14.0 3.9 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII90306.1 - 0.63 9.7 2.2 1.2 8.8 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle MbeD_MobD PF04899.7 KII90307.1 - 0.19 11.6 6.6 0.48 10.3 1.4 2.3 1 1 1 2 2 2 0 MbeD/MobD like UBN2 PF14223.1 KII90308.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII90308.1 - 0.00031 20.3 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KII90308.1 - 0.043 13.7 6.8 0.087 12.7 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII90308.1 - 0.29 10.8 2.6 2.6 7.7 1.6 2.1 2 0 0 2 2 2 0 Zinc knuckle Corona_nucleoca PF00937.13 KII90308.1 - 0.61 8.9 5.7 0.96 8.3 4.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DDE_1 PF03184.14 KII90309.1 - 1.6e-18 66.6 0.0 1.2e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KII90309.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Pox_RNA_Pol_19 PF05320.7 KII90312.1 - 1 9.1 4.1 1 9.0 2.9 1.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2890 PF11081.3 KII90312.1 - 3.8 7.5 11.6 4.5 7.2 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2407_C PF13373.1 KII90312.1 - 5 7.0 5.4 5.8 6.8 3.7 1.2 1 1 0 1 1 1 0 DUF2407 C-terminal domain eIF3_subunit PF08597.5 KII90312.1 - 6.8 6.1 13.3 6.9 6.1 9.2 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2732 PF10809.3 KII90314.1 - 0.33 10.5 2.6 0.38 10.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2732) Tet_JBP PF12851.2 KII90315.1 - 1.7e-08 33.9 0.0 2.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DASH_Dad2 PF08654.5 KII90315.1 - 0.18 11.8 0.2 0.35 10.8 0.0 1.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 UBN2 PF14223.1 KII90316.1 - 9.4e-10 38.3 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII90316.1 - 2.5e-05 23.8 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KII90316.1 - 0.002 17.7 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1877 PF08974.5 KII90316.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) FHA PF00498.21 KII90317.1 - 0.035 14.2 0.1 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 FHA domain CAP59_mtransfer PF11735.3 KII90318.1 - 1.8e-44 151.8 0.0 2.8e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 OTCace_N PF02729.16 KII90319.1 - 1.8e-46 157.3 0.0 2.4e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KII90319.1 - 1.5e-40 138.6 0.0 2.1e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Peptidase_C37 PF05416.7 KII90319.1 - 0.062 11.5 0.1 0.086 11.1 0.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glycogen_syn PF05693.8 KII90320.1 - 0 1082.7 0.0 0 1082.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 KII90320.1 - 8.4e-08 32.5 1.2 6.8e-07 29.5 0.2 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KII90320.1 - 1.3e-07 31.2 0.0 0.00012 21.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KII90320.1 - 1.8e-07 30.9 0.8 4.6e-07 29.5 0.2 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Ribonuc_L-PSP PF01042.16 KII90321.1 - 1.9e-32 111.5 0.0 2.1e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribonuc_L-PSP PF01042.16 KII90322.1 - 9.9e-35 118.9 0.0 1.1e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribonuc_L-PSP PF01042.16 KII90323.1 - 1e-31 109.2 0.0 1.1e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP JmjC PF02373.17 KII90324.1 - 1.9e-38 131.2 0.1 4.1e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 KII90324.1 - 7.7e-16 57.3 0.4 2.8e-15 55.5 0.3 2.0 2 0 0 2 2 2 1 jmjN domain zf-HC5HC2H PF13771.1 KII90324.1 - 2.6e-12 46.6 1.7 2.6e-12 46.6 1.2 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KII90324.1 - 1.3e-11 44.4 2.4 3.5e-11 43.0 0.7 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain Helicase_C PF00271.26 KII90327.1 - 5.8e-15 54.9 0.0 1.5e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII90327.1 - 7.4e-13 48.3 0.0 1.7e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII90327.1 - 0.0025 17.6 0.4 0.026 14.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KII90327.1 - 0.039 12.5 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer zf-MYND PF01753.13 KII90329.1 - 3e-08 33.4 14.2 3e-08 33.4 9.9 1.8 2 0 0 2 2 2 1 MYND finger Mating_N PF12731.2 KII90329.1 - 0.092 12.6 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein beta 1 Zn_Tnp_IS91 PF14319.1 KII90329.1 - 0.56 9.7 9.0 1.7 8.1 6.2 1.8 1 0 0 1 1 1 0 Transposase zinc-binding domain GST_N PF02798.15 KII90330.1 - 1.1e-09 38.2 0.0 3.2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KII90330.1 - 5.6e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII90330.1 - 2.1e-05 24.3 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII90330.1 - 0.0081 16.6 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII90330.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2844 PF11005.3 KII90331.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2844) ENTH PF01417.15 KII90332.1 - 7.5e-52 174.4 0.1 1.6e-51 173.4 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KII90332.1 - 4.5e-05 22.2 4.7 0.00011 21.0 0.0 2.2 2 0 0 2 2 2 1 ANTH domain Methyltrn_RNA_4 PF09936.4 KII90332.1 - 0.53 9.7 2.2 0.6 9.5 0.5 1.8 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase DUF4613 PF15390.1 KII90332.1 - 2.7 6.0 12.0 4.2 5.4 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PI-PLC-Y PF00387.14 KII90334.1 - 0.0057 16.6 0.1 0.0082 16.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Cellulase PF00150.13 KII90335.1 - 9.3e-32 110.3 1.9 1.5e-31 109.6 1.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_1 PF00133.17 KII90336.1 - 2.1e-208 693.1 0.0 1e-207 690.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KII90336.1 - 5.8e-36 123.5 0.1 1.4e-35 122.2 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KII90336.1 - 1.2e-16 60.3 0.1 5.3e-08 31.9 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KII90336.1 - 2.5e-10 39.9 0.1 4e-06 26.2 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 KII90336.1 - 0.0017 17.2 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 KII90336.1 - 0.039 13.0 0.1 0.4 9.7 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF1524 PF07510.6 KII90337.1 - 7.8e-14 51.7 0.0 9.9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Peptidase_C12 PF01088.16 KII90338.1 - 1.5e-47 161.5 0.0 4.2e-46 156.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Mid1 PF12929.2 KII90339.1 - 3.3e-81 273.2 0.3 3.7e-81 273.0 0.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KII90339.1 - 0.49 10.7 5.7 2.3 8.6 0.6 2.3 1 1 0 2 2 2 0 Fz domain ASXH PF13919.1 KII90340.1 - 1.1e-17 64.1 0.0 1.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Asx homology domain ABC1 PF03109.11 KII90341.1 - 2.6e-28 98.3 0.0 4.2e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KII90341.1 - 0.002 17.9 0.1 0.0058 16.3 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII90341.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rhv PF00073.15 KII90341.1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 picornavirus capsid protein DUF21 PF01595.15 KII90342.1 - 2.7e-29 101.7 1.2 4.5e-29 101.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KII90342.1 - 1.2e-06 28.1 1.0 0.03 14.1 0.1 3.5 3 0 0 3 3 3 3 CBS domain FhuF PF06276.7 KII90345.1 - 0.026 14.4 1.1 0.048 13.6 0.4 1.6 1 1 1 2 2 2 0 Ferric iron reductase FhuF-like transporter CBF PF03914.12 KII90346.1 - 2.8e-33 114.6 0.0 2.4e-32 111.6 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.15 KII90346.1 - 0.0053 15.1 0.2 0.011 14.0 0.1 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KII90346.1 - 0.0091 15.8 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 MFS_1 PF07690.11 KII90347.1 - 6.4e-20 71.1 36.1 9.6e-20 70.5 25.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FYVE_2 PF02318.11 KII90348.1 - 3.1 7.7 10.9 4 7.3 1.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.11 KII90349.1 - 7.2e-26 90.7 44.2 5.7e-24 84.4 23.3 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII90349.1 - 1.6e-06 27.0 2.1 1.6e-06 27.0 1.5 3.8 2 2 1 3 3 3 2 Sugar (and other) transporter EthD PF07110.6 KII90350.1 - 7.2e-05 23.6 0.4 0.52 11.2 0.0 2.3 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 KII90350.1 - 0.12 12.6 0.1 21 5.4 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4286) DUF2288 PF10052.4 KII90350.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) p450 PF00067.17 KII90351.1 - 2.8e-60 204.1 0.0 1.3e-59 201.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Collagen PF01391.13 KII90352.1 - 0.0046 16.4 34.3 0.0046 16.4 23.7 6.5 4 2 2 6 6 6 2 Collagen triple helix repeat (20 copies) DUF1875 PF08961.5 KII90353.1 - 0.00014 21.2 0.2 0.00024 20.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) DUF2353 PF09789.4 KII90353.1 - 0.00032 20.0 1.7 0.00046 19.5 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) APG6 PF04111.7 KII90353.1 - 0.034 13.2 1.4 0.045 12.7 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 KII90353.1 - 0.041 13.5 2.4 0.096 12.4 1.6 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Prp19 PF08606.6 KII90353.1 - 0.36 10.5 4.2 0.26 11.0 0.5 2.1 1 1 1 2 2 2 0 Prp19/Pso4-like GED PF02212.13 KII90353.1 - 0.73 9.7 8.0 3.3 7.6 0.3 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF904 PF06005.7 KII90353.1 - 1.4 9.2 4.8 4.5 7.6 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) FUSC PF04632.7 KII90353.1 - 2.5 6.4 7.1 2.9 6.2 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acetyltransf_1 PF00583.19 KII90354.1 - 5.1e-10 39.2 0.1 9.6e-10 38.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII90354.1 - 1.7e-07 31.3 0.0 4.5e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII90354.1 - 7.3e-06 26.0 0.0 0.0001 22.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII90354.1 - 8.7e-05 22.3 0.0 0.0013 18.5 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII90354.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein HrpF PF06266.7 KII90354.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 HrpF protein Methyltransf_16 PF10294.4 KII90355.1 - 3.5e-18 65.6 0.0 7.8e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KII90355.1 - 0.022 15.3 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain KRAB PF01352.22 KII90355.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 KRAB box GidB PF02527.10 KII90355.1 - 0.089 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G CMD PF02627.15 KII90356.1 - 3.5e-13 49.1 0.8 2.3e-11 43.3 0.3 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Atrophin-1 PF03154.10 KII90357.1 - 0.15 10.1 3.6 0.26 9.4 2.5 1.3 1 0 0 1 1 1 0 Atrophin-1 family DUF3043 PF11241.3 KII90357.1 - 4.1 6.9 7.4 18 4.8 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Kdo PF06293.9 KII90361.1 - 7.7e-09 34.9 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII90361.1 - 6.2e-06 26.1 0.1 0.00092 19.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KII90361.1 - 5.6e-05 22.4 0.0 0.00013 21.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 KII90361.1 - 0.00045 19.4 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KII90361.1 - 0.0012 18.2 0.0 0.083 12.2 0.0 2.1 1 1 0 1 1 1 1 RIO1 family SEP PF08059.8 KII90362.1 - 7.7e-24 83.7 0.0 2.1e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KII90362.1 - 4.7e-16 58.6 0.0 7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain MAGE PF01454.14 KII90363.1 - 1.9e-38 131.7 0.1 1.3e-34 119.2 0.0 2.3 2 0 0 2 2 2 2 MAGE family Sigma70_ner PF04546.8 KII90363.1 - 0.95 9.0 14.1 1.1 8.8 2.1 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region PI-PLC-X PF00388.14 KII90364.1 - 3.3e-42 143.3 0.0 5.7e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KII90364.1 - 2.3e-28 98.5 0.0 3.5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF4528 PF15031.1 KII90364.1 - 0.088 12.5 0.1 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4528) C2 PF00168.25 KII90364.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 C2 domain SPC25 PF06703.6 KII90365.1 - 1.1 8.7 4.9 2.1 7.8 3.4 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sugar_tr PF00083.19 KII90366.1 - 3.5e-121 404.9 18.4 4.1e-121 404.6 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90366.1 - 1.3e-17 63.6 44.0 7.3e-11 41.3 16.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.6 KII90366.1 - 0.62 9.7 9.2 0.12 12.0 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) PIN_4 PF13638.1 KII90367.1 - 9.3e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 PIN domain Abhydrolase_4 PF08386.5 KII90368.1 - 3.2e-20 71.9 0.1 4.1e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KII90368.1 - 0.046 13.5 0.1 0.065 13.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family HtrL_YibB PF09612.5 KII90368.1 - 0.088 12.0 0.0 0.51 9.5 0.0 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Methyltransf_32 PF13679.1 KII90369.1 - 0.078 12.6 1.2 1.7 8.2 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Abhydrolase_1 PF00561.15 KII90370.1 - 1e-12 48.1 0.0 2.4e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII90370.1 - 2.4e-07 30.8 0.0 1.2e-06 28.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII90370.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.16 KII90371.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KII90371.1 - 0.014 14.3 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 KII90371.1 - 0.014 15.2 0.2 0.05 13.5 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KII90372.1 - 4.1e-39 134.2 0.0 5.1e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII90372.1 - 4.9e-11 42.9 0.3 7.7e-11 42.3 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII90372.1 - 3.1e-06 26.0 0.1 4.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII90372.1 - 1.8e-05 24.3 0.1 3.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KII90372.1 - 0.0027 16.7 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 KII90372.1 - 0.0034 17.9 0.0 0.0055 17.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 KII90372.1 - 0.0041 17.0 0.1 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KII90372.1 - 0.017 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KII90372.1 - 0.054 13.1 0.1 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 KR domain DapB_N PF01113.15 KII90372.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ion_trans PF00520.26 KII90373.1 - 3.2e-97 323.6 94.7 5.1e-36 123.8 4.5 5.4 6 0 0 6 6 6 4 Ion transport protein PCI PF01399.22 KII90374.1 - 5.8e-07 29.7 2.1 5e-05 23.5 0.0 3.2 3 0 0 3 3 3 2 PCI domain Sugar_tr PF00083.19 KII90375.1 - 4.4e-118 394.7 23.3 5.1e-118 394.5 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90375.1 - 6.1e-18 64.6 53.2 2.4e-11 42.9 18.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_28 PF00295.12 KII90376.1 - 7.1e-30 104.0 4.8 1.1e-29 103.4 3.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Prefoldin PF02996.12 KII90377.1 - 2.5e-27 94.8 3.0 3.1e-27 94.5 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KII90377.1 - 1.7e-05 24.4 0.3 3.1e-05 23.6 0.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.5 KII90377.1 - 0.0013 18.9 5.3 0.051 13.7 0.8 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family COG2 PF06148.6 KII90377.1 - 0.0015 18.4 2.8 0.91 9.3 0.4 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.15 KII90377.1 - 0.0093 15.7 5.7 0.055 13.2 0.3 2.2 2 0 0 2 2 2 1 Prefoldin subunit TMF_TATA_bd PF12325.3 KII90377.1 - 0.013 15.2 1.5 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding XkdW PF09636.5 KII90377.1 - 0.021 14.6 1.2 0.095 12.5 0.1 2.0 2 0 0 2 2 2 0 XkdW protein Seryl_tRNA_N PF02403.17 KII90377.1 - 0.025 14.6 1.5 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 KII90377.1 - 0.05 13.9 4.9 1.3 9.3 0.2 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Bacillus_HBL PF05791.6 KII90377.1 - 0.059 12.7 4.1 0.34 10.2 0.2 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TACC PF05010.9 KII90377.1 - 0.11 12.2 4.5 0.29 10.8 3.1 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) IncA PF04156.9 KII90377.1 - 0.12 12.0 3.7 1.5 8.3 0.3 2.0 2 0 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 KII90377.1 - 0.15 11.8 3.6 6.7 6.5 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.8 KII90377.1 - 0.15 12.4 2.3 3.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) IFT46_B_C PF12317.3 KII90377.1 - 0.16 11.3 1.0 7.3 5.8 0.1 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Spc7 PF08317.6 KII90377.1 - 0.18 10.4 5.7 1.2 7.7 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein IL6 PF00489.12 KII90377.1 - 0.22 11.0 5.0 0.11 12.0 1.0 1.9 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family FlaC_arch PF05377.6 KII90377.1 - 0.22 11.4 2.0 6.6 6.7 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 KII90377.1 - 0.24 11.3 4.4 0.86 9.6 0.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor Baculo_PEP_C PF04513.7 KII90377.1 - 0.26 11.1 6.8 2.3 8.0 0.4 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4298 PF14131.1 KII90377.1 - 0.29 11.0 2.8 12 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) BLOC1_2 PF10046.4 KII90377.1 - 0.32 11.1 6.6 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.8 KII90377.1 - 0.35 10.2 4.1 3.3 7.0 0.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1409 PF07197.7 KII90377.1 - 0.35 10.9 2.5 10 6.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) V_ATPase_I PF01496.14 KII90377.1 - 0.37 8.5 3.2 0.89 7.3 2.2 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 KII90377.1 - 0.37 10.8 5.4 0.38 10.7 0.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit NPV_P10 PF05531.7 KII90377.1 - 0.52 10.6 5.5 1.3 9.3 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 KII90377.1 - 0.63 9.9 8.7 0.54 10.1 0.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tektin PF03148.9 KII90377.1 - 0.72 8.3 6.2 3.6 6.0 0.2 2.0 2 0 0 2 2 2 0 Tektin family Cortex-I_coil PF09304.5 KII90377.1 - 1.4 9.0 5.6 8 6.5 0.5 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF2347 PF09804.4 KII90378.1 - 1.5e-47 162.2 0.0 3.4e-47 161.0 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 KII90378.1 - 1.2e-05 24.0 0.0 1.2 7.5 0.1 3.1 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.5 KII90378.1 - 0.038 13.7 0.0 0.25 11.0 0.0 2.0 1 1 0 1 1 1 0 Stabilization of polarity axis zf-rbx1 PF12678.2 KII90378.1 - 0.96 9.5 4.8 0.95 9.6 0.1 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger Pkinase PF00069.20 KII90379.1 - 0.0002 20.5 0.0 0.002 17.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90379.1 - 0.0044 16.1 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KII90380.1 - 0.0082 15.2 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII90380.1 - 0.017 14.0 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KII90380.1 - 0.17 10.9 0.2 1.2 8.2 0.1 1.9 1 1 0 1 1 1 0 Protein kinase domain ATP_bind_1 PF03029.12 KII90383.1 - 4e-77 258.9 0.0 6.5e-77 258.2 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KII90383.1 - 5.8e-05 22.6 0.1 0.0011 18.4 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KII90383.1 - 0.00098 19.0 0.0 0.0026 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KII90383.1 - 0.0019 17.7 0.1 0.0063 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KII90383.1 - 0.0039 17.9 3.1 0.028 15.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.15 KII90383.1 - 0.0043 15.8 0.2 0.37 9.4 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit CbiA PF01656.18 KII90383.1 - 0.0043 16.4 0.4 0.022 14.1 0.3 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 KII90383.1 - 0.005 16.7 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KII90383.1 - 0.0065 15.2 0.0 2.3 6.9 0.0 2.3 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 KII90383.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 KII90383.1 - 0.016 14.3 0.1 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin FeoB_N PF02421.13 KII90383.1 - 0.021 14.0 0.1 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.17 KII90383.1 - 0.026 13.9 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KII90383.1 - 0.027 14.5 0.0 0.062 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KII90383.1 - 0.042 13.3 0.0 9.1 5.6 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KII90383.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KII90383.1 - 0.11 11.3 0.0 0.37 9.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Arf PF00025.16 KII90383.1 - 0.12 11.6 0.0 0.7 9.1 0.0 2.2 3 0 0 3 3 3 0 ADP-ribosylation factor family Adeno_IVa2 PF02456.10 KII90383.1 - 0.12 11.0 0.1 0.19 10.3 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF258 PF03193.11 KII90383.1 - 0.16 11.1 0.1 0.7 9.0 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 KII90384.1 - 6.6e-75 251.6 0.0 7.4e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90384.1 - 2.3e-33 115.3 0.0 2.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII90384.1 - 0.0017 18.1 0.1 0.017 14.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII90384.1 - 0.0037 16.2 0.0 0.1 11.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KII90384.1 - 0.027 13.3 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KII90385.1 - 1.2e-74 250.7 0.0 1.3e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90385.1 - 2.2e-33 115.4 0.0 2.7e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII90385.1 - 0.00035 20.3 0.1 0.014 15.0 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII90385.1 - 0.0088 15.0 0.0 0.11 11.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KII90385.1 - 0.048 12.4 0.0 0.093 11.5 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KII90385.1 - 0.15 11.0 0.3 0.42 9.6 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3435 PF11917.3 KII90386.1 - 4.9e-05 22.2 0.0 0.00011 21.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) DUF2721 PF11026.3 KII90389.1 - 0.038 13.6 0.2 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pkinase_Tyr PF07714.12 KII90391.1 - 2.2e-10 40.0 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII90391.1 - 5.1e-08 32.3 0.0 6.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KII90391.1 - 0.027 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII90391.1 - 0.051 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KII90391.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FHA PF00498.21 KII90393.1 - 6.2e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain NPV_P10 PF05531.7 KII90393.1 - 0.0017 18.5 2.3 0.047 13.9 0.1 2.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KII90393.1 - 0.0086 15.9 0.4 0.046 13.5 0.2 2.3 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 KII90393.1 - 0.04 13.6 4.5 0.062 13.0 0.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 KII90393.1 - 0.096 12.8 7.3 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 Syntaxin Prefoldin_2 PF01920.15 KII90393.1 - 0.1 12.3 1.2 3.5 7.4 0.0 3.0 2 2 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 KII90393.1 - 0.16 11.8 2.6 0.26 11.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 KII90393.1 - 0.17 11.5 4.2 3 7.4 2.9 2.4 1 1 0 1 1 1 0 Mnd1 family THOC7 PF05615.8 KII90393.1 - 0.28 11.4 3.7 2.2 8.5 0.3 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4515 PF14988.1 KII90393.1 - 0.33 10.5 5.7 0.58 9.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF1843 PF08898.5 KII90393.1 - 0.33 11.0 4.5 2.1 8.4 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) AAA_13 PF13166.1 KII90393.1 - 0.36 9.2 1.3 0.56 8.6 0.9 1.2 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 KII90393.1 - 0.39 11.4 1.9 0.79 10.4 0.2 2.2 2 0 0 2 2 2 0 Occludin homology domain FlxA PF14282.1 KII90393.1 - 0.59 10.1 7.8 0.37 10.7 0.1 3.3 2 1 1 3 3 3 0 FlxA-like protein DUF4140 PF13600.1 KII90393.1 - 0.72 10.3 6.5 1.5 9.2 0.2 3.2 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF883 PF05957.8 KII90393.1 - 0.74 10.2 8.4 2.4 8.6 1.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HAUS-augmin3 PF14932.1 KII90393.1 - 0.77 8.8 4.1 0.45 9.6 0.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.1 KII90393.1 - 0.9 8.6 4.7 0.36 9.9 0.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KII90393.1 - 1.5 8.4 5.3 7.8 6.0 3.6 2.2 1 1 0 1 1 1 0 IncA protein SAC3_GANP PF03399.11 KII90394.1 - 4.6e-24 85.1 0.0 8.2e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF29 PF01724.11 KII90394.1 - 0.061 13.1 0.6 0.16 11.8 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF29 Folate_carrier PF01770.13 KII90394.1 - 0.8 8.1 0.1 1.2 7.5 0.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Glyco_hydro_16 PF00722.16 KII90396.1 - 6.9e-19 67.8 0.9 2e-18 66.3 0.3 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 KII90397.1 - 3.6e-52 176.9 0.2 3.6e-52 176.9 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KII90397.1 - 3e-08 33.7 0.0 6.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KII90397.1 - 0.005 16.5 0.1 0.041 13.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 2 Gti1_Pac2 PF09729.4 KII90398.1 - 4e-56 189.4 0.0 1.6e-55 187.5 0.0 1.8 2 0 0 2 2 2 1 Gti1/Pac2 family Peptidase_M22 PF00814.20 KII90399.1 - 2.3e-69 233.8 0.1 2.8e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Pkinase PF00069.20 KII90400.1 - 9.2e-39 133.1 0.0 1.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90400.1 - 4e-30 104.7 0.0 5.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII90400.1 - 0.00066 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII90400.1 - 0.0055 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KII90400.1 - 0.0062 16.3 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII90400.1 - 0.0074 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KII90401.1 - 1.5e-38 132.3 0.0 1.8e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII90401.1 - 1.6e-34 119.2 0.0 1.8e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII90401.1 - 5.6e-05 22.2 0.0 8.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII90401.1 - 0.00071 19.3 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII90401.1 - 0.035 13.1 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KII90401.1 - 0.059 12.5 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KII90401.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MMR_HSR1 PF01926.18 KII90402.1 - 3.5e-20 72.0 0.1 7.5e-15 54.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KII90402.1 - 6.6e-08 31.9 0.1 3.8e-06 26.2 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KII90402.1 - 3.4e-06 26.6 0.0 0.00029 20.3 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KII90402.1 - 8e-05 22.5 0.4 0.37 10.5 0.1 3.2 2 1 1 3 3 3 1 Dynamin family ArgK PF03308.11 KII90402.1 - 0.00059 18.6 0.0 0.0012 17.6 0.0 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 KII90402.1 - 0.0012 19.3 0.1 0.73 10.3 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KII90402.1 - 0.0017 17.5 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KII90402.1 - 0.017 15.1 0.4 2 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.11 KII90402.1 - 0.038 13.1 0.3 0.18 10.8 0.1 2.0 2 0 0 2 2 2 0 AIG1 family cobW PF02492.14 KII90402.1 - 0.068 12.6 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KII90402.1 - 0.07 12.8 0.1 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIR_2 PF13676.1 KII90402.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 TIR domain AAA_17 PF13207.1 KII90402.1 - 0.16 12.8 0.4 4.6 8.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KII90402.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Dehydrin PF00257.14 KII90403.1 - 0.45 10.8 5.2 0.56 10.5 3.6 1.2 1 0 0 1 1 1 0 Dehydrin Inositol_P PF00459.20 KII90404.1 - 1.2e-51 175.6 0.0 8e-51 172.9 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.20 KII90405.1 - 1.5e-41 142.2 0.0 2e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90405.1 - 3.2e-35 121.4 0.0 4e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII90405.1 - 0.028 13.7 0.0 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KII90405.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KII90405.1 - 0.13 11.2 0.2 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KII90406.1 - 1.5e-41 142.1 0.0 1.8e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII90406.1 - 8.5e-38 129.9 0.0 1.1e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.6 KII90406.1 - 0.0018 17.2 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KII90406.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2955 PF11168.3 KII90407.1 - 0.058 13.0 0.4 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) Ferric_reduct PF01794.14 KII90407.1 - 0.063 13.3 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DEAD PF00270.24 KII90408.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase MtmB PF05369.7 KII90408.1 - 0.11 10.6 0.1 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB WD40 PF00400.27 KII90409.1 - 7.1e-49 162.0 20.6 1.7e-11 43.5 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KII90409.1 - 0.00015 21.5 6.3 1.2 8.8 0.1 4.1 3 1 1 4 4 4 3 Transcription factor IIIC subunit delta N-term GTP_EFTU PF00009.22 KII90410.1 - 1.7e-56 190.6 0.0 2.7e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KII90410.1 - 1.5e-35 121.3 0.1 4.1e-35 119.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 KII90410.1 - 3.2e-28 97.3 0.0 6.8e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KII90410.1 - 4.8e-22 77.6 0.0 1.4e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KII90410.1 - 4e-13 49.2 0.0 9.9e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Pkinase PF00069.20 KII90411.1 - 3.7e-37 127.8 0.0 5.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90411.1 - 5.8e-34 117.3 0.0 9.6e-34 116.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII90411.1 - 6.5e-06 26.0 0.2 2.7e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KII90411.1 - 0.0016 17.3 0.1 0.0024 16.7 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KII90411.1 - 0.0026 16.8 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII90411.1 - 0.0036 16.6 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family ABC1 PF03109.11 KII90411.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family YrbL-PhoP_reg PF10707.4 KII90411.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EcKinase PF02958.15 KII90411.1 - 0.054 12.6 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kinase-like PF14531.1 KII90411.1 - 0.056 12.3 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1242 PF06842.7 KII90412.1 - 2e-18 65.5 1.4 2.8e-18 65.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.8 KII90412.1 - 0.33 10.9 0.1 0.33 10.9 0.1 1.6 2 0 0 2 2 2 0 LST-1 protein OPT PF03169.10 KII90413.1 - 8.1e-197 655.4 64.4 9.2e-197 655.2 44.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RCR PF12273.3 KII90417.1 - 0.00019 21.9 2.5 0.0003 21.3 1.7 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Nitrate_red_gam PF02665.9 KII90417.1 - 0.00038 19.8 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Nitrate reductase gamma subunit AftA_N PF12250.3 KII90417.1 - 0.00048 18.9 0.4 0.00056 18.7 0.3 1.0 1 0 0 1 1 1 1 Arabinofuranosyltransferase N terminal Shisa PF13908.1 KII90417.1 - 0.0012 19.0 0.2 0.0016 18.6 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Syndecan PF01034.15 KII90417.1 - 0.0033 17.0 0.3 0.0064 16.1 0.2 1.4 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.13 KII90417.1 - 0.0061 16.3 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A ASFV_J13L PF05568.6 KII90417.1 - 0.0073 15.8 0.2 0.01 15.3 0.1 1.4 1 1 0 1 1 1 1 African swine fever virus J13L protein EphA2_TM PF14575.1 KII90417.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KII90417.1 - 0.019 13.2 0.0 0.024 12.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KII90417.1 - 0.029 13.9 0.2 0.053 13.0 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Lamp PF01299.12 KII90417.1 - 0.046 12.8 0.1 0.046 12.8 0.1 1.8 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF3357 PF11837.3 KII90417.1 - 0.061 13.1 0.1 0.13 12.0 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Bac_Ubq_Cox PF01654.12 KII90417.1 - 0.067 11.5 0.5 0.089 11.1 0.4 1.2 1 1 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Cytochrom_B_N PF00033.14 KII90417.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB P12 PF12669.2 KII90417.1 - 2.7 8.2 5.1 9 6.5 1.5 2.1 1 1 1 2 2 2 0 Virus attachment protein p12 family Hydantoinase_A PF01968.13 KII90420.1 - 1.5e-89 299.9 0.0 2.2e-89 299.3 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KII90420.1 - 1.7e-55 187.2 0.5 1.9e-52 177.2 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region SseB_C PF14581.1 KII90420.1 - 0.097 12.5 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF1708 PF08101.6 KII90421.1 - 1.3e-20 73.6 0.0 8.7e-20 70.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KII90421.1 - 0.23 11.0 0.0 0.98 9.0 0.0 2.1 2 1 0 2 2 2 0 RhoGAP domain zf-Di19 PF05605.7 KII90423.1 - 0.0012 18.8 1.2 0.0012 18.8 0.8 1.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KII90423.1 - 0.12 12.7 5.9 0.064 13.6 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KII90425.1 - 0.0049 17.1 0.1 0.0049 17.1 0.1 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII90425.1 - 0.0093 16.2 0.1 0.0093 16.2 0.1 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII90425.1 - 0.11 12.8 0.7 5.3 7.5 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Mif2_N PF15624.1 KII90425.1 - 5.7 7.5 8.0 45 4.6 4.1 2.5 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RNase_PH PF01138.16 KII90426.1 - 2.6e-16 60.1 0.1 3.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KII90426.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Trm112p PF03966.11 KII90427.1 - 6.9e-18 64.7 0.0 1.2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Trm112p-like protein CDC45 PF02724.9 KII90428.1 - 1.8 6.5 9.1 2.6 5.9 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_3 PF13358.1 KII90431.1 - 1.2e-08 34.8 0.0 1.2e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease AhpC-TSA PF00578.16 KII90432.1 - 1.1e-33 115.5 0.0 1.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII90432.1 - 1.3e-13 50.6 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KII90432.1 - 1.4e-10 40.5 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Glyco_transf_9 PF01075.12 KII90432.1 - 0.13 11.5 0.1 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Peptidase_M48 PF01435.13 KII90433.1 - 1e-23 84.1 0.0 3.5e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M48 Terminase_6 PF03237.10 KII90433.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family SR-25 PF10500.4 KII90434.1 - 0.0022 17.5 11.4 0.0035 16.8 7.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MRP-S26 PF14943.1 KII90434.1 - 0.035 13.6 5.2 0.065 12.7 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 GBP_C PF02841.9 KII90434.1 - 0.13 11.4 8.2 0.25 10.4 5.7 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CDC45 PF02724.9 KII90434.1 - 0.42 8.6 9.2 0.56 8.1 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KII90434.1 - 0.64 9.5 15.9 1.1 8.8 11.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zf-CCHC PF00098.18 KII90434.1 - 1.1 9.2 11.4 0.092 12.7 3.2 2.2 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.24 KII90437.1 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KII90437.1 - 0.0037 16.6 0.2 0.0064 15.8 0.1 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T4SS-DNA_transf PF02534.9 KII90437.1 - 0.0088 14.6 0.0 0.0088 14.6 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 KII90437.1 - 0.02 14.7 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NAD_binding_9 PF13454.1 KII90439.1 - 0.00041 20.1 0.0 0.0017 18.1 0.0 2.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding DUF3337 PF11816.3 KII90440.1 - 1.3e-41 143.1 0.1 1.2e-40 139.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 KII90440.1 - 9.5e-31 104.5 18.5 6.1e-08 32.2 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat CBM_20 PF00686.14 KII90441.1 - 5.6e-31 106.0 0.1 1.4e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 KII90441.1 - 4.4e-21 75.5 0.6 7.1e-21 74.9 0.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KII90441.1 - 1.7e-12 47.2 0.0 4.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.20 KII90442.1 - 7.1e-11 41.7 0.0 8.4e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90442.1 - 9.3e-05 21.6 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII90442.1 - 0.00011 21.9 0.6 0.00014 21.6 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII90443.1 - 9.1e-27 93.7 0.0 1.1e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII90443.1 - 1.1e-26 93.5 0.0 1.4e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII90443.1 - 4.7e-06 25.7 0.0 8.6e-06 24.9 0.0 1.3 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.12 KII90444.1 - 1e-22 80.4 0.0 1.2e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII90444.1 - 1.5e-19 70.2 0.0 1.7e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII90444.1 - 0.0016 17.5 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF2863 PF11062.3 KII90445.1 - 0.089 10.8 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Polysacc_deac_1 PF01522.16 KII90446.1 - 2.8e-27 94.8 0.0 4.3e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_88 PF07470.8 KII90447.1 - 4.9e-15 55.4 0.2 4.9e-15 55.4 0.1 2.1 2 1 1 3 3 3 1 Glycosyl Hydrolase Family 88 Macoilin PF09726.4 KII90447.1 - 0.61 8.2 11.6 0.76 7.9 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_pp85 PF04637.7 KII90447.1 - 0.91 7.7 3.3 1.2 7.3 2.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tmemb_cc2 PF10267.4 KII90447.1 - 1.2 7.6 5.9 1.6 7.2 4.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DNA_pol_viral_N PF00242.12 KII90447.1 - 2.7 6.9 8.7 3.7 6.4 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RAP1 PF07218.6 KII90447.1 - 3.3 5.6 15.5 4.3 5.3 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF262 PF03235.9 KII90448.1 - 7e-16 58.8 0.1 1.2e-15 58.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF262 Apt1 PF10351.4 KII90448.1 - 0.23 10.2 2.5 0.4 9.4 1.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMC_N PF02463.14 KII90449.1 - 8.1e-66 221.4 0.0 2.9e-65 219.5 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KII90449.1 - 7.5e-23 80.7 0.8 2.8e-21 75.6 0.1 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KII90449.1 - 6.4e-15 56.0 5.1 6.4e-15 56.0 3.6 5.9 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 KII90449.1 - 3e-14 53.6 1.9 2.9e-06 27.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII90449.1 - 6.9e-06 25.5 0.7 3.8e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KII90449.1 - 0.00017 20.2 58.2 0.00018 20.1 16.2 5.2 5 0 0 5 5 5 3 AAA domain AAA_15 PF13175.1 KII90449.1 - 0.0004 19.5 0.1 0.0004 19.5 0.1 3.1 2 2 1 3 3 2 1 AAA ATPase domain Reo_sigmaC PF04582.7 KII90449.1 - 0.0021 17.3 26.8 0.066 12.3 3.7 4.9 3 2 2 5 5 5 3 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KII90449.1 - 0.0052 16.6 4.2 0.0052 16.6 2.9 8.1 4 2 3 7 7 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 KII90449.1 - 0.04 14.0 0.2 0.04 14.0 0.1 6.7 5 1 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.22 KII90449.1 - 0.11 12.8 24.9 9.5 6.5 3.7 5.6 3 2 0 3 3 3 0 ABC transporter NIF PF03031.13 KII90450.1 - 9.2e-09 35.1 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pro_isomerase PF00160.16 KII90451.1 - 1.6e-45 155.1 0.9 1.8e-45 154.9 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Toxin_54 PF15533.1 KII90452.1 - 0.17 12.1 0.8 0.29 11.4 0.6 1.3 1 0 0 1 1 1 0 Putative toxin 54 DUF2116 PF09889.4 KII90452.1 - 0.4 10.5 3.4 0.99 9.2 2.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2197 PF09963.4 KII90453.1 - 0.5 10.3 5.7 1 9.3 1.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-IS66 PF13005.2 KII90453.1 - 8 6.5 8.0 4.9 7.2 0.2 2.7 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 HypA PF01155.14 KII90454.1 - 1.2 8.8 6.7 14 5.4 1.2 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF262 PF03235.9 KII90455.1 - 7.7e-18 65.2 0.7 1.9e-17 63.9 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 MAD PF05557.8 KII90456.1 - 8.8e-40 136.5 54.7 1.4e-39 135.7 37.9 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein ALIX_LYPXL_bnd PF13949.1 KII90456.1 - 5.5e-06 25.5 37.5 5.5e-06 25.5 26.0 3.6 3 1 1 4 4 4 1 ALIX V-shaped domain binding to HIV MRP-S26 PF14943.1 KII90456.1 - 0.0066 16.0 14.4 0.0066 16.0 10.0 5.9 4 2 2 6 6 6 1 Mitochondrial ribosome subunit S26 SYCE1 PF15233.1 KII90456.1 - 0.047 13.6 0.1 0.047 13.6 0.1 6.7 2 1 4 6 6 6 0 Synaptonemal complex central element protein 1 Glyco_trans_1_4 PF13692.1 KII90457.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 E1-N PF14463.1 KII90457.1 - 0.077 12.5 0.5 0.16 11.5 0.3 1.5 1 1 0 1 1 1 0 E1 N-terminal domain LamB_YcsF PF03746.11 KII90458.1 - 5e-73 245.1 0.0 5.7e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family F-box-like PF12937.2 KII90460.1 - 3e-05 23.6 0.1 8.6e-05 22.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII90460.1 - 0.0087 15.6 3.4 0.016 14.8 0.3 2.8 2 1 0 2 2 2 1 F-box domain AHS2 PF02626.10 KII90461.1 - 3.2e-67 226.6 0.0 5.1e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KII90461.1 - 1.4e-60 204.1 0.0 3.5e-60 202.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KII90461.1 - 4.3e-34 117.7 0.0 1.1e-33 116.4 0.0 1.6 2 0 0 2 2 2 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 KII90461.1 - 5.6e-34 116.5 0.0 1.8e-33 114.9 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KII90461.1 - 5.6e-28 97.0 0.0 1.1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KII90461.1 - 4.6e-12 46.0 0.1 9.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KII90461.1 - 3.8e-10 39.0 0.0 1.2e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KII90461.1 - 2.9e-07 30.0 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KII90461.1 - 0.0041 16.4 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KII90461.1 - 0.006 16.2 0.2 0.018 14.6 0.2 1.8 1 1 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.6 KII90461.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KII90461.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain Nudc_N PF14050.1 KII90461.1 - 0.12 12.3 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. Vitellogenin_N PF01347.17 KII90461.1 - 1 7.5 0.1 1.6 6.8 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region Glyco_hydro_16 PF00722.16 KII90462.1 - 4.3e-06 26.1 0.0 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 KII90463.1 - 2.1e-05 23.8 0.0 6.7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2193 PF09959.4 KII90464.1 - 0.004 15.4 7.8 8.9 4.4 0.0 5.4 1 1 4 6 6 6 5 Uncharacterized protein conserved in archaea (DUF2193) UNC45-central PF11701.3 KII90464.1 - 0.063 12.9 0.0 2.6e+02 1.1 0.0 5.5 8 0 0 8 8 8 0 Myosin-binding striated muscle assembly central DUF566 PF04484.7 KII90465.1 - 0.22 11.0 3.5 0.3 10.5 2.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) CybS PF05328.7 KII90471.1 - 1.1e-37 128.6 0.0 1.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 CybS DUF2892 PF11127.3 KII90471.1 - 0.65 9.8 2.9 1 9.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Glyco_transf_11 PF01531.11 KII90472.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 11 Hus1 PF04005.7 KII90481.1 - 1.6e-55 188.1 0.0 1.9e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein DUF3815 PF12821.2 KII90482.1 - 0.59 10.0 10.6 0.18 11.7 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3815) DUF983 PF06170.7 KII90482.1 - 6.6 6.9 8.5 0.65 10.1 0.5 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF983) F-box-like PF12937.2 KII90485.1 - 2.2e-06 27.2 0.1 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like Longin PF13774.1 KII90485.1 - 0.065 12.7 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Regulated-SNARE-like domain DUF1758 PF05585.7 KII90486.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Perm-CXXC PF15629.1 KII90487.1 - 0.051 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Permuted single zf-CXXC unit PgpA PF04608.8 KII90487.1 - 0.069 12.9 5.8 0.14 11.9 1.1 2.3 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A LrgB PF04172.11 KII90487.1 - 0.15 11.1 13.1 0.013 14.6 4.2 2.1 1 1 1 2 2 2 0 LrgB-like family UXS1_N PF11803.3 KII90488.1 - 0.076 12.7 0.0 0.076 12.7 0.0 2.7 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Fungal_trans PF04082.13 KII90488.1 - 0.092 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3815 PF12821.2 KII90488.1 - 0.095 12.6 8.0 0.97 9.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) DUF983 PF06170.7 KII90488.1 - 1.8 8.7 5.7 1.4 9.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) PNP_UDP_1 PF01048.15 KII90489.1 - 3.5e-32 111.2 0.1 4.1e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF566 PF04484.7 KII90490.1 - 3.2 7.1 7.0 4.1 6.8 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1118 PF06549.7 KII90491.1 - 1.8 8.7 4.5 10 6.2 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1118) VPS28 PF03997.7 KII90492.1 - 6.9e-63 211.6 0.0 8e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DNA_ligase_OB_2 PF14743.1 KII90494.1 - 1.6e-25 88.5 0.4 3.1e-25 87.6 0.3 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 KII90494.1 - 5.2e-17 61.8 0.0 1.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain SWIM PF04434.12 KII90494.1 - 1.2e-05 24.6 1.8 0.091 12.2 0.1 2.7 2 0 0 2 2 2 2 SWIM zinc finger MIP-T3 PF10243.4 KII90494.1 - 0.041 12.3 43.0 0.063 11.7 29.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cpn60_TCP1 PF00118.19 KII90495.1 - 1e-116 390.5 2.3 1.2e-116 390.2 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.13 KII90496.1 - 4.9e-26 91.1 0.0 8.4e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII90496.1 - 5.6e-09 35.7 11.2 1.1e-08 34.7 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain polyprenyl_synt PF00348.12 KII90497.1 - 3.5e-71 239.1 0.0 5e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase zf-MYND PF01753.13 KII90499.1 - 7e-11 41.8 17.5 1.6e-10 40.6 12.1 1.7 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII90499.1 - 1.1 9.2 9.2 2.1 8.2 6.4 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KII90500.1 - 1.7e-09 37.4 15.7 4.2e-09 36.1 10.9 1.7 1 1 0 1 1 1 1 MYND finger DUF4279 PF14106.1 KII90500.1 - 0.0037 17.1 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4279) DnaJ PF00226.26 KII90501.1 - 2.8e-21 75.0 2.1 7.9e-21 73.5 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.23 KII90501.1 - 7.4e-16 57.0 9.6 0.00014 21.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KII90501.1 - 9e-16 57.2 23.0 8.2e-12 44.6 0.4 5.5 4 2 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KII90501.1 - 8.1e-14 50.3 21.4 0.00015 21.4 0.0 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII90501.1 - 6.5e-10 39.4 25.5 4.8e-07 30.2 0.4 5.5 3 2 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KII90501.1 - 1.9e-09 36.6 7.2 0.053 13.3 0.0 5.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII90501.1 - 9e-09 35.2 20.1 0.0067 16.9 0.2 7.6 3 2 4 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KII90501.1 - 9.4e-09 35.3 10.3 6.7e-06 26.1 0.6 3.8 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KII90501.1 - 2.3e-07 30.4 4.5 0.12 12.6 0.2 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII90501.1 - 1.1e-06 28.8 24.4 0.059 13.7 0.2 5.9 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KII90501.1 - 5.6e-06 26.1 6.8 0.022 14.6 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII90501.1 - 6.6e-06 25.5 1.4 0.11 12.3 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII90501.1 - 2.4e-05 24.4 17.5 2.7 8.6 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII90501.1 - 0.00021 21.1 18.8 0.05 13.5 0.4 5.0 5 2 1 6 6 6 3 Tetratricopeptide repeat DUF3808 PF10300.4 KII90501.1 - 0.023 13.2 0.2 0.12 10.9 0.0 2.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3808) Zn_clus PF00172.13 KII90502.1 - 1.6e-06 27.9 12.3 3.1e-06 26.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII90502.1 - 1.2e-05 24.2 1.1 8.4e-05 21.5 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tetraspannin PF00335.15 KII90504.1 - 0.019 14.2 13.8 0.02 14.1 9.0 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF1951 PF09188.5 KII90504.1 - 0.062 13.2 0.2 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) NKAIN PF05640.9 KII90504.1 - 0.13 11.1 5.6 0.13 11.2 2.2 1.9 1 1 1 2 2 2 0 Na,K-Atpase Interacting protein DUF4083 PF13314.1 KII90504.1 - 0.57 10.0 4.5 12 5.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) FA_desaturase PF00487.19 KII90504.1 - 1.1 8.6 5.7 2.5 7.4 3.9 1.6 1 1 0 1 1 1 0 Fatty acid desaturase CRAL_TRIO PF00650.15 KII90507.1 - 5.3e-25 87.7 0.0 1.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KII90507.1 - 1.4e-06 28.3 0.1 4.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain UPF0203 PF05254.7 KII90508.1 - 9.8e-17 60.5 0.9 6.6e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 KII90508.1 - 0.12 12.2 1.6 3.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 KII90508.1 - 0.81 9.7 4.6 3.9 7.5 0.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb ADH_N PF08240.7 KII90509.1 - 6.6e-29 99.8 3.1 6.6e-29 99.8 2.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII90509.1 - 4.8e-24 84.3 0.2 9.2e-24 83.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII90509.1 - 0.0017 19.2 0.1 0.0028 18.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII90509.1 - 0.0083 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.7 KII90509.1 - 0.019 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 KII90509.1 - 0.034 14.0 0.2 0.078 12.8 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_26 PF13659.1 KII90509.1 - 0.11 12.5 0.4 0.24 11.4 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase domain Nipped-B_C PF12830.2 KII90510.1 - 8.4e-52 175.5 0.9 2.6e-51 173.9 0.6 1.9 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KII90510.1 - 6.6e-15 54.6 0.6 1.6e-13 50.3 0.1 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 KII90510.1 - 6e-06 26.4 4.6 0.0012 19.0 0.3 4.3 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KII90510.1 - 0.00083 19.2 0.1 0.8 9.9 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 KII90510.1 - 0.013 15.9 4.0 1.4 9.4 0.1 5.0 3 1 1 4 4 4 0 HEAT-like repeat FANCI_S2 PF14676.1 KII90510.1 - 0.034 14.0 1.0 1.1 9.0 0.0 3.7 5 0 0 5 5 5 0 FANCI solenoid 2 Aldo_ket_red PF00248.16 KII90511.1 - 2.1e-60 203.9 0.1 2.3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PCP_red PF08369.5 KII90511.1 - 6.7 6.6 6.2 27 4.7 0.3 3.2 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit HA2 PF04408.18 KII90512.1 - 1.4e-21 76.3 0.0 3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KII90512.1 - 2.4e-12 46.5 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KII90512.1 - 7.4e-11 41.8 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KII90512.1 - 2.1e-08 33.8 0.1 3.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII90512.1 - 0.00031 20.8 0.0 0.00081 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII90512.1 - 0.013 15.2 1.1 0.034 13.8 0.7 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 KII90512.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 KII90512.1 - 0.059 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain KaiC PF06745.8 KII90512.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC MlrC_C PF07171.7 KII90512.1 - 0.084 12.4 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 MlrC C-terminus Arch_ATPase PF01637.13 KII90512.1 - 0.089 12.4 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 KII90512.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DIOX_N PF14226.1 KII90513.1 - 1.3e-30 106.2 0.0 1.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII90513.1 - 6.2e-20 71.3 0.0 9.7e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0172 PF03665.8 KII90514.1 - 9.7e-48 162.2 0.0 1.3e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 KII90514.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cep57_MT_bd PF06657.8 KII90515.1 - 7.3e-25 86.7 0.2 7.3e-25 86.7 0.1 3.3 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KII90515.1 - 2.6e-10 40.0 9.5 2.6e-10 40.0 6.6 3.1 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 IncA PF04156.9 KII90515.1 - 0.041 13.4 32.2 0.49 9.9 15.1 2.5 1 1 1 2 2 2 0 IncA protein HALZ PF02183.13 KII90515.1 - 1.2 8.9 0.0 1.2 8.9 0.0 3.7 4 1 1 5 5 5 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 KII90515.1 - 2.6 5.8 11.2 4.1 5.1 7.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IZUMO PF15005.1 KII90515.1 - 3.8 7.5 5.4 2.5 8.1 1.2 2.4 2 1 1 3 3 3 0 Izumo sperm-egg fusion TMPIT PF07851.8 KII90515.1 - 9.9 5.1 5.6 3.7 6.5 1.0 2.0 2 0 0 2 2 2 0 TMPIT-like protein Hpt PF01627.18 KII90516.1 - 4.6e-09 36.1 0.1 7.3e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Hpt domain CoA_transf_3 PF02515.12 KII90517.1 - 9.4e-68 227.2 0.0 1.3e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Transket_pyr PF02779.19 KII90518.1 - 6.8e-66 221.1 0.0 1.1e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KII90518.1 - 2.2e-57 194.0 0.0 3e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Ribosomal_L23 PF00276.15 KII90519.1 - 6.6e-18 64.4 0.7 1.5e-17 63.3 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 KII90519.1 - 1.2e-16 60.4 17.1 1.2e-16 60.4 11.9 2.1 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Med3 PF11593.3 KII90519.1 - 0.15 11.2 2.2 0.18 11.0 1.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YihI PF04220.7 KII90519.1 - 0.32 10.3 4.0 0.63 9.3 2.8 1.4 1 1 0 1 1 1 0 Der GTPase activator (YihI) DUF663 PF04950.7 KII90521.1 - 7.7e-89 297.5 1.2 9.4e-89 297.2 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KII90521.1 - 4.9e-29 99.6 0.0 1.6e-28 98.0 0.0 1.9 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KII90521.1 - 9.4e-07 28.4 0.0 0.00062 19.2 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KII90521.1 - 9.5e-06 26.4 3.6 9.5e-05 23.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KII90521.1 - 6e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KII90521.1 - 0.00014 21.7 0.1 0.00047 20.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KII90521.1 - 0.00017 21.6 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KII90521.1 - 0.00089 19.1 0.1 0.0025 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KII90521.1 - 0.0012 19.2 0.0 0.0012 19.2 0.0 2.1 2 0 0 2 2 1 1 ABC transporter Miro PF08477.8 KII90521.1 - 0.0012 19.3 0.0 0.0035 17.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 KII90521.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 3.0 3 1 0 3 3 1 1 AAA domain NACHT PF05729.7 KII90521.1 - 0.002 17.7 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KII90521.1 - 0.0025 18.0 0.2 0.0079 16.3 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KII90521.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KII90521.1 - 0.0029 16.8 0.1 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KII90521.1 - 0.0052 16.2 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 KII90521.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 KII90521.1 - 0.009 15.6 0.0 0.029 13.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KII90521.1 - 0.0097 15.8 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 KII90521.1 - 0.012 15.3 0.2 0.026 14.2 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 KII90521.1 - 0.012 15.5 0.9 0.023 14.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KII90521.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 KII90521.1 - 0.016 14.6 0.0 0.061 12.8 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KII90521.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KII90521.1 - 0.058 13.1 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 KII90521.1 - 0.064 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KII90521.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_C_2 PF13307.1 KII90522.1 - 1.1e-52 178.3 0.0 2.2e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KII90522.1 - 2.4e-40 137.7 0.0 5.7e-39 133.3 0.0 2.3 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KII90522.1 - 0.0025 17.3 0.0 0.39 10.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_19 PF13245.1 KII90522.1 - 0.0039 16.8 0.1 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KII90522.1 - 0.005 16.9 0.0 3.3 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KII90522.1 - 0.005 16.0 0.1 1.6 7.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 KII90522.1 - 0.026 14.3 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit His_Phos_1 PF00300.17 KII90523.1 - 3.9e-15 56.2 0.0 5.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.16 KII90524.1 - 8.1e-60 202.0 0.0 9.2e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PCP_red PF08369.5 KII90524.1 - 0.7 9.7 3.8 1.7 8.5 0.5 2.8 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Ras PF00071.17 KII90525.1 - 1.4e-54 183.8 0.0 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII90525.1 - 1.3e-15 57.9 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII90525.1 - 1.3e-06 27.8 0.0 2e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KII90525.1 - 0.0025 17.0 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KII90525.1 - 0.052 12.6 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KII90525.1 - 0.16 11.4 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.18 KII90526.1 - 2.8e-37 128.6 0.7 5.3e-27 94.8 1.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII90526.1 - 1.4e-06 28.3 1.7 7.4e-06 26.0 0.7 2.2 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal AKAP7_NLS PF10469.4 KII90527.1 - 2.8e-27 95.8 0.0 1.2e-23 83.9 0.0 2.7 2 1 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KII90527.1 - 5.3e-06 26.2 0.0 1.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily FAA_hydrolase_N PF09298.6 KII90527.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal Sugar_tr PF00083.19 KII90528.1 - 2.6e-43 148.2 12.8 3.9e-43 147.6 8.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90528.1 - 9e-22 77.2 20.5 7.6e-12 44.5 2.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_51K PF01512.12 KII90529.1 - 3.4e-48 163.1 0.0 5e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KII90529.1 - 4.9e-21 73.6 0.9 4.9e-21 73.6 0.6 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KII90529.1 - 3.5e-07 29.9 0.0 9.4e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 SLBB domain F-box-like PF12937.2 KII90530.1 - 4.8e-07 29.3 1.0 1.7e-06 27.6 0.7 2.0 1 0 0 1 1 1 1 F-box-like BTB PF00651.26 KII90531.1 - 8.2e-11 41.8 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Mu-conotoxin PF05374.7 KII90532.1 - 5.2 6.9 7.0 0.43 10.4 0.5 2.3 2 0 0 2 2 2 0 Mu-Conotoxin Helicase_C PF00271.26 KII90534.1 - 2.9e-16 59.1 0.1 9.4e-16 57.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII90534.1 - 0.0024 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Gpi16 PF04113.9 KII90535.1 - 4.6e-140 467.3 0.0 6.1e-138 460.3 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component F1F0-ATPsyn_F PF10791.4 KII90536.1 - 2.1e-25 88.7 0.0 2.4e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KII90536.1 - 0.068 13.2 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f EB1 PF03271.12 KII90537.1 - 1.2e-15 57.2 0.8 2.2e-15 56.4 0.5 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KII90537.1 - 1.3e-06 28.3 0.3 2.5e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Matrilin_ccoil PF10393.4 KII90537.1 - 0.046 13.0 0.2 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Suppressor_APC PF11414.3 KII90537.1 - 0.049 13.4 0.7 0.13 12.0 0.5 1.7 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Peptidase_S9 PF00326.16 KII90539.1 - 1.5e-48 164.8 0.6 2.1e-48 164.3 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII90539.1 - 4.7e-10 39.3 0.0 2.5e-09 37.0 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 KII90539.1 - 0.00049 18.6 0.0 0.15 10.5 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Lactonase PF10282.4 KII90539.1 - 0.063 12.3 0.0 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ribosomal_L10 PF00466.15 KII90540.1 - 3.9e-17 62.0 0.0 5.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HEAT_2 PF13646.1 KII90541.1 - 2.9e-40 136.4 2.8 3.1e-17 62.6 0.1 4.0 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 KII90541.1 - 2e-26 89.7 0.1 0.0002 21.4 0.0 6.6 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.17 KII90541.1 - 5.8e-12 44.6 0.1 0.0051 16.7 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KII90541.1 - 6e-11 42.5 0.5 0.0079 16.6 0.1 5.5 4 2 1 5 5 5 2 HEAT-like repeat Arm PF00514.18 KII90541.1 - 1.2e-06 28.0 0.2 0.08 12.8 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 KII90541.1 - 0.11 12.6 0.0 13 6.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) Adaptin_binding PF10199.4 KII90545.1 - 2.9e-09 37.3 1.3 1.2e-08 35.2 0.2 2.4 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 T2SE PF00437.15 KII90549.1 - 0.00024 20.0 0.0 0.00039 19.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 KII90549.1 - 0.0094 15.4 0.1 0.03 13.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII90549.1 - 0.016 15.3 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KII90549.1 - 0.016 14.9 0.2 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Herpes_ori_bp PF02399.10 KII90549.1 - 0.035 12.0 0.0 0.052 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein HpcH_HpaI PF03328.9 KII90550.1 - 5.2e-42 143.2 0.0 1.1e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KII90550.1 - 3.8e-11 42.4 0.0 3.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CwfJ_C_1 PF04677.10 KII90551.1 - 3.1e-33 114.0 0.1 4.4e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KII90551.1 - 3.5e-23 81.9 4.9 1.8e-22 79.6 0.0 2.9 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Chitin_synth_1 PF01644.12 KII90552.1 - 1.8e-86 288.0 0.1 2.8e-86 287.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KII90552.1 - 4.8e-32 109.4 0.1 1e-31 108.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KII90552.1 - 7.4e-23 80.7 1.4 5.8e-18 64.5 0.1 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KII90552.1 - 6.6e-07 29.3 0.0 2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KII90552.1 - 3.6e-05 23.5 12.1 0.00023 20.9 8.4 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 NmrA PF05368.8 KII90554.1 - 2.4e-36 125.1 0.0 3.3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII90554.1 - 4.6e-19 69.1 0.1 5.9e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII90554.1 - 0.00019 20.9 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KII90554.1 - 0.0015 18.4 0.3 0.0022 17.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KII90554.1 - 0.0016 17.2 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KII90554.1 - 0.0049 17.1 0.2 0.008 16.4 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII90554.1 - 0.0053 15.7 0.0 0.061 12.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 KII90554.1 - 0.056 13.1 0.2 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 KR domain F-box-like PF12937.2 KII90555.1 - 0.0011 18.6 1.3 0.0025 17.4 0.5 2.1 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 KII90555.1 - 0.0053 16.3 0.0 0.025 14.2 0.0 2.2 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 KII90557.1 - 3.6e-06 26.3 0.0 5.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90557.1 - 0.015 14.4 0.0 0.03 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Ecl1 PF12855.2 KII90559.1 - 7.2e-05 22.0 0.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 2 Life-span regulatory factor DUF3586 PF12131.3 KII90559.1 - 0.058 13.4 0.2 0.4 10.7 0.2 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) DUF1634 PF07843.6 KII90560.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) Complex1_LYR PF05347.10 KII90563.1 - 0.41 10.4 2.9 1.2 8.9 1.6 2.0 1 1 1 2 2 2 0 Complex 1 protein (LYR family) Fmp27_WPPW PF10359.4 KII90563.1 - 0.73 8.1 4.5 0.79 8.0 3.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CsbD PF05532.7 KII90564.1 - 7.8e-15 54.2 13.2 3e-09 36.4 2.0 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 KII90564.1 - 0.14 12.2 0.6 0.42 10.7 0.1 2.1 1 1 2 3 3 3 0 Heat shock protein 9/12 FKBP_C PF00254.23 KII90565.1 - 5.9e-31 106.3 0.0 6.8e-31 106.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase OGFr_N PF04664.8 KII90568.1 - 4.3e-55 186.3 0.1 5.8e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF727 PF05303.7 KII90569.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) GATA PF00320.22 KII90571.1 - 0.11 11.8 1.5 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 GATA zinc finger Sensor PF13796.1 KII90571.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative sensor Sec1 PF00995.18 KII90572.1 - 9.5e-136 453.6 0.0 1.2e-135 453.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.7 KII90572.1 - 2.7e-65 220.1 0.3 4e-65 219.5 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KII90572.1 - 1.5e-24 85.7 0.3 1.5e-24 85.7 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Amidase_6 PF12671.2 KII90572.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative amidase domain Mnd1 PF03962.10 KII90573.1 - 0.34 10.5 6.9 0.68 9.5 4.8 1.5 1 0 0 1 1 1 0 Mnd1 family ASXH PF13919.1 KII90573.1 - 0.58 9.9 7.8 2.2 8.0 5.1 2.0 1 1 1 2 2 2 0 Asx homology domain APG6 PF04111.7 KII90573.1 - 1.1 8.2 9.5 1.6 7.7 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TPP_enzyme_N PF02776.13 KII90574.1 - 5.2e-39 133.4 0.5 5.2e-39 133.4 0.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KII90574.1 - 1.4e-16 60.4 0.3 3.2e-16 59.2 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KII90574.1 - 2.1e-07 30.7 0.0 2.9e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.20 KII90575.1 - 2.7e-18 66.4 2.3 3.8e-18 65.9 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII90575.1 - 1.2e-08 35.0 0.1 1.6e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII90575.1 - 2.6e-07 30.4 0.7 3.6e-07 30.0 0.5 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KII90575.1 - 0.033 13.3 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PrpR_N PF06506.6 KII90575.1 - 0.04 13.3 1.6 0.11 11.8 0.8 1.9 2 1 0 2 2 2 0 Propionate catabolism activator GGGtGRT PF14057.1 KII90575.1 - 0.061 12.1 0.4 0.17 10.6 0.1 1.7 2 0 0 2 2 2 0 GGGtGRT protein Yae1_N PF09811.4 KII90576.1 - 1.8e-12 46.5 1.8 3.6e-12 45.6 1.2 1.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal eIF2A PF08662.6 KII90577.1 - 4.5e-08 33.0 0.0 5.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PVL_ORF50 PF07768.6 KII90579.1 - 6 6.8 8.7 12 5.8 6.0 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family Thaumatin PF00314.12 KII90580.1 - 3.2e-64 216.2 16.6 3.7e-64 216.0 11.5 1.0 1 0 0 1 1 1 1 Thaumatin family DSPc PF00782.15 KII90583.1 - 3e-27 94.7 0.0 4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KII90583.1 - 0.0076 16.5 0.1 0.23 11.7 0.0 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family PmrD PF11183.3 KII90583.1 - 0.029 14.1 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Init_tRNA_PT PF04179.7 KII90583.1 - 0.15 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Alg6_Alg8 PF03155.10 KII90585.1 - 8.6e-133 443.5 16.5 9e-103 344.6 2.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family TRI5 PF06330.6 KII90586.1 - 5.7e-15 54.8 0.0 6.8e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KII90586.1 - 0.013 14.7 0.0 0.058 12.6 0.0 1.9 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain HTH_Tnp_Tc5 PF03221.11 KII90587.1 - 2.6e-07 30.3 0.0 3.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KII90588.1 - 2.1e-21 76.0 0.0 3.7e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KII90588.1 - 0.00024 20.8 0.1 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2 PF14223.1 KII90589.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KII90589.1 - 1.7e-06 27.6 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII90589.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1011 PF06237.7 KII90592.1 - 5 7.0 10.1 2.8 7.8 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) Mito_carr PF00153.22 KII90594.1 - 2.8e-30 103.8 0.0 2.8e-11 42.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 KII90595.1 - 1.5e-12 47.0 0.0 2.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain His_Phos_1 PF00300.17 KII90596.1 - 1.2e-20 74.1 0.0 2.1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SKN1 PF03935.10 KII90597.1 - 1.7e-191 636.7 1.1 2e-191 636.5 0.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FGGY_N PF00370.16 KII90600.1 - 3.5e-24 85.4 0.0 5.7e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KII90600.1 - 6.4e-21 74.8 0.0 1.1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pro_isomerase PF00160.16 KII90601.1 - 6.1e-47 159.6 0.2 1.4e-46 158.5 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KII90601.1 - 1.6e-06 27.7 0.2 0.054 13.3 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4504 PF14953.1 KII90602.1 - 2.7e-07 30.1 0.1 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) DUF2592 PF10766.4 KII90603.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Ycf1 PF05758.7 KII90604.1 - 0.18 9.4 1.5 0.25 8.9 1.0 1.1 1 0 0 1 1 1 0 Ycf1 RIO1 PF01163.17 KII90606.1 - 2e-72 242.5 0.0 2e-72 242.5 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KII90606.1 - 6.1e-05 22.8 1.0 0.11 12.1 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KII90606.1 - 0.0031 16.5 0.5 2.5 7.1 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KII90606.1 - 0.035 13.2 0.0 0.073 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain ILVD_EDD PF00920.16 KII90607.1 - 1.4e-196 653.9 0.3 1.6e-196 653.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Zn_clus PF00172.13 KII90609.1 - 1.4e-07 31.2 5.2 1.4e-07 31.2 3.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 KII90609.1 - 1 8.8 5.1 1.4 8.3 3.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Septin PF00735.13 KII90610.1 - 8.2e-30 103.7 0.0 2.3e-09 36.7 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 KII90610.1 - 1.2e-18 66.7 26.4 2.9e-10 39.8 5.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.13 KII90611.1 - 5.1e-46 156.9 0.0 1.6e-16 60.1 0.0 3.7 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.18 KII90611.1 - 1.3e-05 25.1 0.0 4.7e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KII90611.1 - 2.8e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KII90611.1 - 0.036 13.8 0.1 4.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 KII90611.1 - 0.037 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein CM_2 PF01817.16 KII90612.1 - 1.6e-10 40.8 0.0 3.3e-07 30.3 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II Thi4 PF01946.12 KII90613.1 - 1.3e-92 309.1 0.1 1.5e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KII90613.1 - 1.1e-10 41.0 0.5 6.1e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII90613.1 - 1.4e-07 30.7 0.4 5e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KII90613.1 - 1.2e-06 28.5 0.4 1.8e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII90613.1 - 1.8e-06 27.9 0.1 4.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KII90613.1 - 2.3e-06 27.4 1.7 3.4e-05 23.6 0.1 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KII90613.1 - 3e-05 23.0 1.0 0.00014 20.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KII90613.1 - 0.00015 21.9 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII90613.1 - 0.00074 18.0 0.2 0.0013 17.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KII90613.1 - 0.0017 17.5 0.1 0.0028 16.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KII90613.1 - 0.019 13.8 0.3 0.094 11.5 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KII90613.1 - 0.022 13.4 0.4 0.031 12.8 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GRASP55_65 PF04495.9 KII90614.1 - 7.6e-06 25.9 0.0 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KII90614.1 - 3.1e-05 23.7 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KII90614.1 - 0.014 15.6 0.0 0.03 14.4 0.0 1.7 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Acyl-CoA_dh_1 PF00441.19 KII90615.1 - 4.9e-20 72.1 0.1 1.3e-19 70.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KII90615.1 - 1.1e-07 32.1 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII90615.1 - 7.8e-07 28.5 0.1 2.1e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KII90615.1 - 0.0011 19.5 0.0 0.0029 18.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain LRR_4 PF12799.2 KII90616.1 - 0.00013 21.4 0.4 0.11 12.0 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KII90616.1 - 0.00027 20.5 0.5 0.0046 16.6 0.0 3.2 4 0 0 4 4 4 1 F-box-like LRR_8 PF13855.1 KII90616.1 - 0.062 13.0 0.1 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 KII90616.1 - 0.19 12.0 1.6 1.2e+02 3.6 0.2 4.0 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KII90617.1 - 6.2e-09 35.4 0.2 1.7e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII90617.1 - 0.00094 18.7 0.0 0.0033 17.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 KII90617.1 - 0.057 13.5 0.3 36 4.8 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich repeat Fungal_trans PF04082.13 KII90618.1 - 1.3e-31 109.3 0.1 2.5e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII90618.1 - 6.9e-10 38.6 8.8 1.7e-09 37.4 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Heme_oxygenase PF01126.15 KII90619.1 - 1.5e-29 103.0 0.1 1.9e-28 99.4 0.1 2.4 1 1 0 1 1 1 1 Heme oxygenase Glyco_trans_4_3 PF12000.3 KII90619.1 - 0.089 12.4 0.2 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 Gkycosyl transferase family 4 group Fungal_trans PF04082.13 KII90620.1 - 1.1e-30 106.3 0.1 2e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII90620.1 - 0.00032 20.5 4.3 0.00065 19.5 3.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KII90622.1 - 1.5e-46 158.4 0.0 1.9e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KII90623.1 - 2.7e-07 30.2 1.7 7.2e-07 28.8 1.2 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KII90623.1 - 0.0047 16.5 0.3 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 F-box domain DUF3623 PF12291.3 KII90623.1 - 0.17 10.8 0.8 0.24 10.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Sugar_tr PF00083.19 KII90624.1 - 1e-128 429.7 30.6 1.2e-128 429.5 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90624.1 - 6.4e-20 71.1 38.3 4.7e-15 55.1 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_B_palm PF14792.1 KII90625.1 - 2e-15 56.8 0.0 2.2e-14 53.4 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KII90625.1 - 8e-15 54.2 0.2 2.9e-14 52.4 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 KII90625.1 - 5.1e-13 49.0 0.1 5.2e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KII90625.1 - 3.3e-10 39.3 0.1 8.7e-10 38.0 0.0 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 KII90625.1 - 1.1e-05 25.4 0.1 0.00039 20.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 KII90625.1 - 0.0073 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus SNF5 PF04855.7 KII90626.1 - 1.7e-56 191.4 0.0 2.9e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF2419 PF10343.4 KII90627.1 - 6.1e-70 235.7 0.0 4.7e-47 160.6 0.0 3.9 3 1 0 3 3 3 3 Protein of unknown function (DUF2419) NB-ARC PF00931.17 KII90631.1 - 0.00054 18.8 0.3 0.035 12.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 KII90631.1 - 0.008 16.1 0.2 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII90631.1 - 0.012 15.7 0.0 0.06 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KII90631.1 - 0.017 14.8 0.2 0.099 12.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain APS_kinase PF01583.15 KII90631.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 KII90631.1 - 0.018 14.6 0.1 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KII90631.1 - 0.032 14.5 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KII90631.1 - 0.036 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 KII90631.1 - 0.059 12.9 0.3 0.21 11.1 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KII90631.1 - 0.065 13.4 0.3 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KII90631.1 - 0.11 12.3 0.1 0.41 10.5 0.0 1.9 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.9 KII90632.1 - 0.0051 15.8 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 KII90632.1 - 0.012 15.2 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Myb_DNA-bind_3 PF12776.2 KII90635.1 - 2.9e-10 40.6 0.1 5.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain WD40 PF00400.27 KII90636.1 - 4.7e-112 362.3 42.4 6.1e-13 48.1 0.1 10.1 10 0 0 10 10 10 10 WD domain, G-beta repeat PD40 PF07676.7 KII90636.1 - 3.1e-19 68.2 20.9 0.85 9.3 0.0 10.3 10 0 0 10 10 10 7 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KII90636.1 - 1.2e-12 46.8 18.3 0.14 10.2 0.0 7.8 2 2 6 8 8 8 6 Nucleoporin Nup120/160 eIF2A PF08662.6 KII90636.1 - 1.6e-12 47.5 2.4 0.012 15.3 0.1 4.7 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A GH97_N PF14508.1 KII90636.1 - 5.6e-08 32.0 3.4 0.2 10.5 0.0 4.8 4 1 1 5 5 5 3 Glycosyl-hydrolase 97 N-terminal DUF1258 PF06869.7 KII90636.1 - 7.1e-08 31.8 5.2 0.56 9.2 0.0 6.1 2 2 3 6 6 6 3 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 KII90636.1 - 9.2e-07 27.4 8.9 0.07 11.4 0.0 4.6 1 1 2 4 4 4 3 Cytochrome D1 heme domain VEFS-Box PF09733.4 KII90636.1 - 9.5e-07 28.5 0.4 39 3.8 0.0 7.0 2 2 6 8 8 8 0 VEFS-Box of polycomb protein DUF1652 PF07865.6 KII90636.1 - 4e-05 23.1 0.0 21 4.8 0.0 6.0 5 3 2 7 7 7 0 Protein of unknown function (DUF1652) Hira PF07569.6 KII90636.1 - 5.1e-05 22.5 3.4 11 5.1 0.0 6.8 1 1 5 8 8 8 0 TUP1-like enhancer of split Nbas_N PF15492.1 KII90636.1 - 0.00039 19.6 2.8 1.1 8.2 0.0 6.0 1 1 6 7 7 7 1 Neuroblastoma-amplified sequence, N terminal Root_cap PF06830.6 KII90636.1 - 0.016 15.0 0.1 1.1 9.1 0.0 3.4 4 0 0 4 4 4 0 Root cap PLD_C PF12357.3 KII90636.1 - 0.028 13.9 4.0 16 5.1 0.0 5.8 7 1 0 7 7 6 0 Phospholipase D C terminal DUF4123 PF13503.1 KII90636.1 - 0.038 13.9 0.0 15 5.5 0.0 3.6 1 1 2 4 4 4 0 Domain of unknown function (DUF4123) AcetylCoA_hyd_C PF13336.1 KII90636.1 - 0.051 13.2 0.0 42 3.7 0.0 4.0 4 1 0 4 4 4 0 Acetyl-CoA hydrolase/transferase C-terminal domain Proteasome_A_N PF10584.4 KII90636.1 - 0.11 11.8 39.0 15 5.0 0.2 9.6 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature GCV_T_C PF08669.6 KII90636.1 - 0.23 11.5 15.6 26 4.9 0.0 6.9 6 2 2 9 9 9 0 Glycine cleavage T-protein C-terminal barrel domain EBP PF05241.7 KII90636.1 - 0.63 9.0 3.8 14 4.6 0.1 4.2 2 2 3 5 5 5 0 Emopamil binding protein Tuberculin PF12198.3 KII90637.1 - 0.81 9.6 4.0 11 6.0 0.3 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein DUF605 PF04652.11 KII90637.1 - 1 8.7 5.4 1.1 8.5 3.7 1.0 1 0 0 1 1 1 0 Vta1 like eIF_4EBP PF05456.6 KII90640.1 - 0.054 13.2 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Sugar_tr PF00083.19 KII90641.1 - 7.8e-105 351.0 12.0 1.8e-104 349.8 8.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90641.1 - 7.8e-21 74.1 53.4 5.9e-15 54.8 18.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.19 KII90642.1 - 2e-66 223.1 48.6 8.3e-43 146.0 10.5 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KII90642.1 - 2e-37 128.5 0.0 3e-18 66.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KII90642.1 - 3.9e-30 103.5 7.2 5.6e-26 90.2 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KII90642.1 - 1.6e-14 53.7 0.1 4.6e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KII90642.1 - 3.6e-08 33.0 0.1 0.00024 20.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KII90642.1 - 5.2e-08 33.0 0.1 0.00036 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KII90642.1 - 7.4e-07 28.4 0.0 4.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KII90642.1 - 1.2e-06 28.7 0.1 0.075 13.1 0.1 3.1 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KII90642.1 - 7.9e-05 22.3 0.1 0.11 12.1 0.1 3.3 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.1 KII90642.1 - 0.0001 21.7 0.5 0.043 13.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KII90642.1 - 0.00021 21.6 0.1 0.46 10.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KII90642.1 - 0.00033 20.1 0.7 0.079 12.3 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KII90642.1 - 0.00063 19.6 0.1 0.56 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KII90642.1 - 0.0014 18.6 0.0 1.4 8.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KII90642.1 - 0.0022 18.8 0.0 0.89 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KII90642.1 - 0.0026 17.6 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KII90642.1 - 0.0029 17.1 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KII90642.1 - 0.0031 16.9 0.1 3.1 7.1 0.2 2.8 3 0 0 3 3 3 1 AAA-like domain Arch_ATPase PF01637.13 KII90642.1 - 0.0036 17.0 0.0 0.68 9.5 0.0 2.6 3 0 0 3 3 2 1 Archaeal ATPase AAA PF00004.24 KII90642.1 - 0.0046 17.1 0.0 5.3 7.2 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KII90642.1 - 0.0048 17.3 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 KII90642.1 - 0.0077 16.2 0.2 0.83 9.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KII90642.1 - 0.01 15.3 0.4 0.85 9.0 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 KII90642.1 - 0.011 15.4 1.0 1.3 8.7 0.3 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 KII90642.1 - 0.021 14.8 0.0 0.91 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KII90642.1 - 0.023 13.7 0.0 4.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Septin UPF0079 PF02367.12 KII90642.1 - 0.038 13.6 3.0 0.26 10.8 0.1 2.6 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KII90642.1 - 0.12 11.9 0.1 2.6 7.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KII90642.1 - 0.14 12.5 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 KII90643.1 - 2.3e-54 181.0 4.3 3e-17 62.0 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Hist_deacetyl PF00850.14 KII90644.1 - 5.9e-61 206.4 0.2 7.9e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NAD_binding_4 PF07993.7 KII90646.1 - 9.9e-35 119.6 0.0 1.4e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII90646.1 - 1.6e-32 112.4 0.0 1.4e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KII90646.1 - 1.1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII90646.1 - 9.3e-07 27.8 0.0 1.9e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII90646.1 - 4.2e-05 23.6 0.0 0.00019 21.4 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KII90646.1 - 0.00014 21.8 0.0 0.0004 20.3 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII90646.1 - 0.00053 19.7 0.1 0.0017 18.0 0.0 2.0 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 KII90646.1 - 0.067 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KII90646.1 - 0.11 11.3 0.0 0.38 9.6 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KII90646.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family GPI-anchored PF10342.4 KII90647.1 - 0.0025 18.2 1.1 0.0068 16.8 0.8 1.7 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADH_zinc_N PF00107.21 KII90648.1 - 4.4e-12 45.6 0.1 8.6e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90648.1 - 1.5e-10 40.7 0.0 2.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII90648.1 - 0.021 15.7 0.0 0.036 14.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 KII90650.1 - 1.5e-47 162.0 46.7 6.6e-46 156.6 33.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KII90650.1 - 1.7e-11 43.0 31.3 3.2e-11 42.1 21.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KII90650.1 - 3.7e-07 29.0 17.0 3.7e-07 29.0 11.8 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter adh_short_C2 PF13561.1 KII90651.1 - 5.7e-26 91.7 0.4 6.5e-26 91.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII90651.1 - 4.1e-10 39.8 6.3 5.7e-10 39.3 4.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Oxidored_nitro PF00148.14 KII90651.1 - 0.00059 18.5 0.0 0.00087 18.0 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase KR PF08659.5 KII90651.1 - 0.0017 18.0 1.2 0.0026 17.4 0.8 1.4 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 KII90651.1 - 0.0061 16.4 1.8 0.013 15.3 1.1 1.7 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII90651.1 - 0.017 14.2 0.3 0.028 13.5 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KII90651.1 - 0.026 13.6 0.4 0.061 12.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KII90651.1 - 0.063 13.2 2.3 0.073 13.0 1.4 1.4 1 1 0 1 1 1 0 NADH(P)-binding Sen15 PF09631.5 KII90652.1 - 3.6e-20 72.0 0.0 4.2e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein MerT PF02411.10 KII90654.1 - 0.1 12.4 0.2 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 MerT mercuric transport protein MFS_1 PF07690.11 KII90655.1 - 2.1e-21 76.0 52.2 1.3e-15 56.9 8.8 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII90655.1 - 4.3e-19 68.4 3.4 4.3e-19 68.4 2.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Carb_kinase PF01256.12 KII90657.1 - 0.029 13.6 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase BTB PF00651.26 KII90658.1 - 2.5e-08 33.8 0.1 6.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 KII90659.1 - 1.3e-33 113.6 0.2 7.1e-07 28.8 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KII90659.1 - 0.0014 16.8 0.0 0.012 13.8 0.0 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KII90659.1 - 0.0014 18.0 0.0 0.0038 16.7 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 KII90659.1 - 0.0015 17.3 0.1 0.0031 16.3 0.1 1.6 1 1 0 1 1 1 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KII90659.1 - 0.012 13.8 0.0 0.02 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KII90659.1 - 0.038 12.7 0.0 1.6 7.4 0.0 2.7 1 1 2 3 3 3 0 Coatomer WD associated region IKI3 PF04762.7 KII90659.1 - 0.15 9.8 0.0 0.21 9.3 0.0 1.3 1 0 0 1 1 1 0 IKI3 family AflR PF08493.5 KII90660.1 - 4.7 6.1 5.5 5.5 5.9 3.8 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein zf-C3HC4_3 PF13920.1 KII90662.1 - 2.6e-08 33.3 10.8 3.8e-08 32.8 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII90662.1 - 4.2e-07 29.6 11.7 6.4e-07 29.1 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KII90662.1 - 3.6e-06 26.6 10.7 5.6e-06 25.9 7.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII90662.1 - 8.4e-06 25.7 12.4 1.2e-05 25.1 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Spt4 PF06093.8 KII90662.1 - 0.00012 21.8 3.7 0.0002 21.1 0.1 2.3 1 1 1 2 2 2 1 Spt4/RpoE2 zinc finger zf-C3HC4 PF00097.20 KII90662.1 - 0.00023 20.7 10.9 0.00037 20.0 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII90662.1 - 0.00068 19.1 10.3 0.0017 17.9 7.2 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain NOB1_Zn_bind PF08772.6 KII90662.1 - 0.046 13.5 1.4 0.095 12.5 1.0 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4_4 PF15227.1 KII90662.1 - 0.07 13.0 13.1 0.13 12.1 9.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TerY-C PF15616.1 KII90662.1 - 0.096 12.6 7.0 0.18 11.7 4.9 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.1 KII90662.1 - 0.21 11.3 5.9 0.38 10.5 4.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KII90662.1 - 0.24 10.9 10.6 1.5 8.4 7.3 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 KII90662.1 - 0.36 10.3 9.8 0.68 9.4 6.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 KII90662.1 - 0.81 9.4 10.8 1.9 8.2 7.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Kin17_mid PF10357.4 KII90663.1 - 1.9e-48 163.2 0.4 3.1e-48 162.5 0.3 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KII90663.1 - 0.0005 20.1 4.1 0.0013 18.8 2.8 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KII90663.1 - 0.021 14.9 3.8 0.021 14.9 2.6 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ecl1 PF12855.2 KII90663.1 - 0.092 12.0 0.8 0.2 11.0 0.6 1.5 1 0 0 1 1 1 0 Life-span regulatory factor zf-C2H2_2 PF12756.2 KII90663.1 - 0.19 11.8 5.3 0.1 12.7 1.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2407_C PF13373.1 KII90664.1 - 6.9e-23 81.1 5.9 4e-18 65.6 1.4 3.2 2 1 0 2 2 2 2 DUF2407 C-terminal domain DUF2407 PF10302.4 KII90664.1 - 2.2e-16 59.8 0.0 3.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KII90664.1 - 0.00019 20.7 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UPF0118 PF01594.11 KII90664.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF2453 PF10507.4 KII90664.1 - 0.089 12.6 0.0 10 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) MtrF PF09472.5 KII90664.1 - 0.098 11.9 0.4 9.2 5.5 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) IBN_N PF03810.14 KII90665.1 - 7.9e-10 38.5 0.0 9.2e-07 28.7 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KII90665.1 - 1e-08 35.3 2.8 0.0019 18.4 0.0 4.7 4 0 0 4 4 4 2 HEAT repeats DUF2435 PF10363.4 KII90665.1 - 0.0018 18.1 0.2 0.0083 16.0 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) HEAT PF02985.17 KII90665.1 - 0.0046 16.9 0.1 0.89 9.8 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat Cse1 PF08506.5 KII90665.1 - 0.009 14.6 0.0 0.02 13.5 0.0 1.6 1 0 0 1 1 1 1 Cse1 DUF77 PF01910.12 KII90665.1 - 0.026 14.1 0.3 0.11 12.1 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF77 HEAT_EZ PF13513.1 KII90665.1 - 0.19 12.2 3.2 2 9.0 0.1 4.4 3 1 1 4 4 4 0 HEAT-like repeat Xpo1 PF08389.7 KII90665.1 - 0.63 9.9 0.0 0.63 9.9 0.0 3.6 4 1 0 4 4 4 0 Exportin 1-like protein PSS PF03034.10 KII90666.1 - 2.9e-98 328.7 13.3 3.9e-98 328.3 9.2 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Zn_clus PF00172.13 KII90667.1 - 2.1e-08 33.9 7.3 4.6e-08 32.8 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 KII90667.1 - 0.26 9.9 6.9 7.1 5.1 4.4 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein NRDE PF05742.7 KII90668.1 - 7.5e-41 140.2 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 NRDE protein Actin PF00022.14 KII90669.1 - 4.1e-80 269.1 0.0 4.7e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Actin DUF4449 PF14613.1 KII90672.1 - 5e-27 94.8 2.3 5e-27 94.8 1.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF167 PF02594.11 KII90673.1 - 2.6e-07 30.4 22.2 7.2 6.6 0.1 9.1 3 1 6 9 9 9 6 Uncharacterised ACR, YggU family COG1872 Vps23_core PF09454.5 KII90673.1 - 0.18 11.4 1.7 19 4.9 0.0 4.0 4 0 0 4 4 4 0 Vps23 core domain ADH_zinc_N PF00107.21 KII90674.1 - 1.1e-11 44.3 0.2 2.2e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90674.1 - 2.8e-10 39.9 0.7 2.5e-09 36.8 0.3 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII90674.1 - 0.037 14.9 0.0 0.071 14.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DEAD PF00270.24 KII90675.1 - 4.2e-13 49.1 0.0 6.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC_6 PF15288.1 KII90675.1 - 4.1e-05 23.1 1.3 0.00012 21.6 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Helicase_C PF00271.26 KII90675.1 - 0.002 17.9 0.0 0.0093 15.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII90675.1 - 0.0029 17.4 0.0 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 KII90678.1 - 5e-14 51.8 10.3 1.1e-08 34.7 1.8 3.3 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 KII90678.1 - 4.2e-08 33.1 1.9 3.7e-05 23.7 0.1 2.8 3 0 0 3 3 3 2 RING-H2 zinc finger zf-RING_5 PF14634.1 KII90678.1 - 1.4e-06 27.8 6.1 0.00056 19.5 0.4 2.9 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.20 KII90678.1 - 1.9e-05 24.2 9.2 4e-05 23.1 0.6 2.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII90678.1 - 4.8e-05 23.3 1.8 4.8e-05 23.3 1.3 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII90678.1 - 9.9e-05 22.1 3.3 0.0025 17.6 0.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KII90678.1 - 0.00029 20.4 6.6 0.0018 17.9 0.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KII90678.1 - 0.032 14.1 1.1 0.86 9.6 0.1 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KII90678.1 - 0.043 13.8 0.8 0.12 12.4 0.5 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KII90678.1 - 2 8.1 6.8 11 5.7 0.8 2.6 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 KII90678.1 - 7.3 6.5 8.0 1.7 8.5 0.7 3.1 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 KII90679.1 - 1.1e-62 211.5 0.0 1.6e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90679.1 - 6.1e-38 130.3 0.0 8.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII90679.1 - 7.9e-10 38.1 0.1 2e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII90679.1 - 0.0042 16.8 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII90679.1 - 0.0043 16.1 0.1 0.061 12.3 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KII90680.1 - 0.00011 21.9 3.4 0.00026 20.6 2.4 1.7 1 1 0 1 1 1 1 F-box-like CENP-F_leu_zip PF10473.4 KII90680.1 - 0.086 12.7 0.1 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dynactin PF12455.3 KII90680.1 - 0.13 11.1 0.5 0.17 10.7 0.3 1.1 1 0 0 1 1 1 0 Dynein associated protein Ferritin_2 PF13668.1 KII90681.1 - 2.4e-46 157.0 0.1 3.9e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 KII90682.1 - 7.6e-48 161.9 5.5 1.3e-47 161.2 3.8 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF4157 PF13699.1 KII90682.1 - 0.038 14.1 0.5 0.11 12.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Rubrerythrin PF02915.12 KII90682.1 - 0.19 12.0 1.5 0.88 9.8 1.1 2.1 1 1 0 1 1 1 0 Rubrerythrin Cohesin_HEAT PF12765.2 KII90684.1 - 0.036 14.0 7.5 63 3.6 0.2 6.0 3 2 3 6 6 6 0 HEAT repeat associated with sister chromatid cohesion zf-B_box PF00643.19 KII90687.1 - 0.00052 19.8 3.8 0.00052 19.8 2.6 2.1 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.1 KII90687.1 - 1.3 8.7 13.3 0.046 13.4 4.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFIID_30kDa PF03540.8 KII90689.1 - 0.29 10.9 2.3 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit adh_short_C2 PF13561.1 KII90691.1 - 1.3e-19 70.9 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GFO_IDH_MocA PF01408.17 KII90692.1 - 8.8e-16 58.5 0.0 2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KII90692.1 - 0.012 15.9 0.0 0.05 14.0 0.0 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.12 KII90692.1 - 0.086 12.6 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain F-box-like PF12937.2 KII90693.1 - 2.8e-07 30.1 1.4 6.3e-07 29.0 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII90693.1 - 0.0027 17.3 0.1 0.0075 15.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain Herpes_U30 PF04523.8 KII90693.1 - 0.007 13.8 0.0 0.0097 13.4 0.0 1.1 1 0 0 1 1 1 1 Herpes virus tegument protein U30 GFO_IDH_MocA PF01408.17 KII90694.1 - 2.4e-16 60.3 0.1 5.1e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII90694.1 - 5.4e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 KII90694.1 - 0.0051 17.1 0.4 0.019 15.3 0.0 2.2 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Acetyltransf_3 PF13302.1 KII90697.1 - 1.3e-21 77.2 0.1 3.2e-21 75.9 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII90697.1 - 1.9e-09 37.4 0.0 4.1e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KII90697.1 - 1.2e-06 28.5 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII90697.1 - 3.8e-05 23.7 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII90697.1 - 0.00018 21.3 0.1 0.00047 20.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII90697.1 - 0.00084 19.4 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NmrA PF05368.8 KII90698.1 - 2.9e-50 170.7 0.0 3.5e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII90698.1 - 1.7e-16 60.7 0.0 2.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII90698.1 - 2.5e-08 32.9 0.0 8.5e-08 31.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII90698.1 - 0.0005 19.5 0.0 0.00091 18.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KII90698.1 - 0.0075 16.2 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain DUF3454 PF11936.3 KII90699.1 - 0.014 15.6 2.4 0.014 15.6 1.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3454) Abhydrolase_4 PF08386.5 KII90700.1 - 4.8e-20 71.3 0.8 1.2e-19 70.0 0.0 2.1 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_1 PF00561.15 KII90700.1 - 7.7e-13 48.5 0.1 4.4e-12 46.0 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII90700.1 - 4.8e-08 33.1 0.0 2.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.24 KII90705.1 - 1.3e-08 34.5 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII90705.1 - 9.1e-08 31.8 0.0 5.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KII90705.1 - 0.01 15.5 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 KII90705.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.2 KII90709.1 - 8.8e-05 22.1 1.0 8.8e-05 22.1 0.7 2.5 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 KII90710.1 - 1.9e-24 86.0 67.1 5e-20 71.5 28.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII90710.1 - 4.2e-05 22.3 8.5 4.2e-05 22.3 5.9 3.9 2 2 2 4 4 4 3 Sugar (and other) transporter SPRY PF00622.23 KII90714.1 - 2.1e-10 40.7 0.1 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain TFIIS_C PF01096.13 KII90715.1 - 3.6e-15 55.2 4.2 3.6e-15 55.2 2.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KII90715.1 - 5.5e-09 35.5 0.6 5.5e-09 35.5 0.4 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 KII90715.1 - 0.02 14.6 9.4 0.17 11.7 0.2 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KII90715.1 - 0.33 10.7 13.4 4.3 7.2 0.1 4.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon AMP-binding PF00501.23 KII90716.1 - 1.3e-70 237.8 0.0 1.7e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 KII90717.1 - 1.2e-70 238.0 0.0 1.3e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII90717.1 - 2.6e-06 28.2 0.0 5.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM PF10378.4 KII90717.1 - 0.027 14.0 1.1 1.9 8.1 0.1 2.6 2 0 0 2 2 2 0 Putative RRM domain zf-MYND PF01753.13 KII90718.1 - 3.9e-06 26.6 11.2 7.5e-06 25.7 7.7 1.5 1 0 0 1 1 1 1 MYND finger CRAL_TRIO_2 PF13716.1 KII90719.1 - 1.2e-32 112.8 0.1 2e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 KII90719.1 - 1.2e-30 106.1 0.0 1.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 KII90719.1 - 0.0002 20.9 0.1 0.00089 18.7 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain Glyco_hydro_88 PF07470.8 KII90720.1 - 4.7e-16 58.7 0.5 8.5e-16 57.9 0.3 1.5 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4387 PF14330.1 KII90721.1 - 9.7e-37 125.2 0.0 2.3e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 KII90721.1 - 3.1e-16 58.8 0.0 6.2e-08 31.4 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1446) bZIP_1 PF00170.16 KII90722.1 - 2.1e-10 40.3 4.9 3.7e-10 39.6 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KII90722.1 - 2.9e-07 30.1 8.9 5.2e-07 29.3 6.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KII90722.1 - 0.0035 17.6 2.3 0.0065 16.7 1.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor GDA1_CD39 PF01150.12 KII90723.1 - 5.6e-92 308.5 0.0 7.4e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KII90723.1 - 0.094 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family adh_short PF00106.20 KII90724.1 - 2.4e-31 108.9 3.6 3.3e-31 108.4 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII90724.1 - 1.7e-18 67.2 0.1 2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII90724.1 - 7.2e-13 48.5 1.9 1e-12 48.0 1.3 1.3 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 KII90724.1 - 0.0014 18.7 0.4 0.41 10.8 0.1 2.7 2 1 0 2 2 2 2 Helix-hairpin-helix domain Epimerase PF01370.16 KII90724.1 - 0.029 13.7 0.1 0.052 12.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.22 KII90725.1 - 8.7e-67 220.8 7.9 3e-25 87.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferritin_2 PF13668.1 KII90726.1 - 8.2e-50 168.3 1.1 1.2e-49 167.7 0.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.1 KII90726.1 - 0.084 13.3 0.9 0.28 11.6 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4439) ADH_zinc_N PF00107.21 KII90727.1 - 2.6e-25 88.4 0.3 7e-25 87.0 0.2 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII90727.1 - 3.9e-16 60.0 0.1 7.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90727.1 - 1.8e-07 30.8 0.0 4.1e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-RNPHF PF08080.7 KII90727.1 - 0.0027 17.1 0.2 0.0056 16.1 0.1 1.5 1 0 0 1 1 1 1 RNPHF zinc finger ELFV_dehydrog PF00208.16 KII90727.1 - 0.0084 15.7 0.1 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ferritin_2 PF13668.1 KII90728.1 - 9.3e-49 164.9 1.3 1.5e-48 164.2 0.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.1 KII90728.1 - 0.051 14.0 1.6 0.16 12.4 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4439) DAO PF01266.19 KII90729.1 - 5.2e-50 170.3 0.1 7.2e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KII90729.1 - 1.5e-06 27.5 0.0 4.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII90729.1 - 2.8e-05 23.1 6.8 2.8e-05 23.1 4.7 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KII90729.1 - 5.6e-05 23.1 0.3 0.00093 19.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KII90729.1 - 0.0048 16.0 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KII90729.1 - 0.0049 16.8 0.4 0.018 15.0 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII90729.1 - 0.0097 14.8 0.4 0.34 9.7 0.3 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.17 KII90729.1 - 0.012 14.4 0.3 0.27 10.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KII90729.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII90729.1 - 0.016 14.2 1.6 0.022 13.8 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 KII90729.1 - 0.02 15.3 3.5 0.034 14.5 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII90729.1 - 0.022 13.2 0.9 0.036 12.5 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KII90729.1 - 0.055 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.23 KII90730.1 - 2.2e-84 283.2 0.0 2.9e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII90730.1 - 7.6e-14 52.4 0.1 1.9e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phenol_monoox PF04663.7 KII90730.1 - 0.049 13.3 0.3 0.35 10.6 0.3 2.2 2 0 0 2 2 2 0 Phenol hydroxylase conserved region DUF3493 PF11998.3 KII90732.1 - 0.086 12.7 0.3 16 5.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) TPR_5 PF12688.2 KII90734.1 - 0.97 9.4 9.0 34 4.4 0.2 4.2 4 0 0 4 4 4 0 Tetratrico peptide repeat Phage_CII PF05269.6 KII90734.1 - 1 9.4 16.6 26 4.9 0.1 5.5 4 2 0 5 5 5 0 Bacteriophage CII protein Metalloenzyme PF01676.13 KII90734.1 - 3.7 6.8 5.5 34 3.6 0.0 3.7 2 2 2 4 4 4 0 Metalloenzyme superfamily DUF2062 PF09835.4 KII90734.1 - 4.3 6.9 5.4 35 3.9 0.0 4.2 5 1 1 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF3181 PF11378.3 KII90737.1 - 0.02 14.9 2.2 72 3.4 0.0 5.5 7 1 0 7 7 7 0 Protein of unknown function (DUF3181) SDF PF00375.13 KII90737.1 - 0.069 11.8 5.2 12 4.4 0.1 4.3 3 2 0 4 4 4 0 Sodium:dicarboxylate symporter family Cadherin_pro PF08758.6 KII90737.1 - 1.7 8.4 5.7 1.4e+02 2.2 0.0 5.5 6 2 0 6 6 6 0 Cadherin prodomain like KR PF08659.5 KII90737.1 - 9.5 5.8 25.9 1.5 8.4 0.2 6.8 3 2 4 8 8 8 0 KR domain Birna_VP5 PF03042.9 KII90738.1 - 0.051 13.0 0.4 0.065 12.7 0.3 1.2 1 0 0 1 1 1 0 Birnavirus VP5 protein Virul_fac_BrkB PF03631.10 KII90739.1 - 0.054 12.8 4.0 0.17 11.2 2.7 1.8 1 1 0 1 1 1 0 Virulence factor BrkB COesterase PF00135.23 KII90741.1 - 1.4e-98 330.9 0.0 1.8e-98 330.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII90741.1 - 4e-07 29.8 0.2 2e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1593 PF07632.6 KII90742.1 - 8.5e-97 323.5 0.0 1.3e-96 322.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 KII90742.1 - 0.0089 14.3 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 1 REJ domain FMN_red PF03358.10 KII90743.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KII90743.1 - 3.6e-05 23.7 0.0 8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KII90743.1 - 0.00083 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Bacteriocin_IIc PF10439.4 KII90743.1 - 1.5 9.0 6.7 1.6 8.9 2.4 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Pkinase PF00069.20 KII90744.1 - 6.6e-49 166.3 0.0 7.9e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90744.1 - 1.5e-24 86.4 0.1 1.3e-23 83.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII90744.1 - 3.9e-05 22.7 0.0 5.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII90744.1 - 0.0029 16.9 0.3 0.0052 16.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KII90744.1 - 0.013 14.5 0.1 0.025 13.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AhpC-TSA PF00578.16 KII90745.1 - 6.4e-29 100.1 0.0 8.1e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII90745.1 - 5e-18 65.0 0.0 6.8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin Linker_histone PF00538.14 KII90746.1 - 4.7e-07 29.8 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family Lipase_3 PF01764.20 KII90747.1 - 4e-23 81.5 0.0 5.3e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KII90747.1 - 0.00021 20.9 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII90747.1 - 0.00075 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KII90747.1 - 0.0042 16.7 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.7 KII90747.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 KII90747.1 - 0.063 13.0 0.1 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 KII90748.1 - 6.4e-56 189.2 0.0 1.6e-55 187.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII90749.1 - 2.6e-58 197.0 0.1 3e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EHN PF06441.7 KII90750.1 - 2.9e-34 117.3 0.8 2.3e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII90750.1 - 5.7e-09 36.1 0.4 1.6e-08 34.7 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII90750.1 - 0.00033 20.2 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 KII90751.1 - 2.9e-70 237.0 0.0 3.4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KII90752.1 - 8.7e-21 74.2 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KII90752.1 - 0.023 14.3 0.2 0.078 12.6 0.0 1.8 2 0 0 2 2 2 0 KR domain rve PF00665.21 KII90753.1 - 6.5e-07 29.4 0.0 8.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain LRRCT PF01463.19 KII90755.1 - 0.012 15.8 0.8 0.036 14.3 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain zf-CCHC PF00098.18 KII90758.1 - 0.081 12.8 5.8 0.15 12.0 4.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KII90758.1 - 0.25 10.8 3.3 0.41 10.1 1.4 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PX PF00787.19 KII90759.1 - 1.3e-13 50.6 0.3 8.1e-12 44.9 0.0 3.1 3 0 0 3 3 3 1 PX domain PLDc PF00614.17 KII90759.1 - 1.4e-12 46.9 0.5 2.4e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KII90759.1 - 5e-12 45.6 0.0 2.9e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Dabb PF07876.7 KII90760.1 - 6.3e-20 71.4 0.0 6.9e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.7 KII90761.1 - 6.8e-19 68.1 0.0 7.5e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain E1_dh PF00676.15 KII90763.1 - 8.6e-81 270.9 0.0 1e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF1049 PF06305.6 KII90764.1 - 0.029 13.8 0.5 0.072 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Podoplanin PF05808.6 KII90764.1 - 0.2 11.1 2.7 0.67 9.4 0.2 2.2 2 0 0 2 2 2 0 Podoplanin DUF1180 PF06679.7 KII90764.1 - 4.8 7.0 9.1 5.8 6.7 4.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3415 PF11895.3 KII90765.1 - 2.7e-33 113.6 1.9 5.9e-33 112.5 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KII90765.1 - 2.5e-29 102.4 0.0 3.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase vATP-synt_AC39 PF01992.11 KII90766.1 - 5.9e-103 344.5 0.0 6.6e-103 344.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit MFS_1 PF07690.11 KII90767.1 - 2.5e-28 98.8 31.3 2.5e-28 98.8 21.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 KII90767.1 - 0.49 10.1 2.4 3.2 7.4 0.1 3.0 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF2614 PF11023.3 KII90767.1 - 1 9.1 3.2 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) DLH PF01738.13 KII90768.1 - 7.3e-23 80.9 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII90768.1 - 1.4e-06 28.1 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII90768.1 - 0.00013 21.9 0.0 0.00085 19.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII90768.1 - 0.0025 17.3 0.1 0.6 9.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF3415 PF11895.3 KII90769.1 - 1.6e-35 120.7 1.5 3.7e-35 119.6 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KII90769.1 - 6.3e-29 101.0 0.0 8.9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase zf-Tim10_DDP PF02953.10 KII90770.1 - 2.7e-19 68.1 7.6 3.5e-19 67.8 5.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 KII90770.1 - 0.098 11.6 0.1 0.1 11.6 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Borrelia_lipo_2 PF06238.6 KII90770.1 - 0.14 12.2 0.1 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein DAHP_synth_1 PF00793.15 KII90771.1 - 4.6e-89 297.7 0.0 5.9e-89 297.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Scm3 PF10384.4 KII90772.1 - 4.7e-13 48.4 0.9 8.3e-13 47.6 0.6 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 3Beta_HSD PF01073.14 KII90773.1 - 7.7e-10 37.9 0.0 1.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII90773.1 - 5.3e-08 32.5 0.0 9.1e-08 31.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII90773.1 - 0.00012 22.1 0.3 0.0039 17.2 0.3 2.4 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII90773.1 - 0.00015 20.7 0.0 0.00087 18.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII90773.1 - 0.076 12.2 0.2 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Mit_KHE1 PF10173.4 KII90774.1 - 3.6e-47 160.6 0.0 5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Sensor PF13796.1 KII90774.1 - 0.064 12.8 0.2 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Putative sensor Mit_KHE1 PF10173.4 KII90775.1 - 1.1e-26 93.8 3.0 1.8e-26 93.1 2.1 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related zf-C2H2 PF00096.21 KII90776.1 - 0.019 15.2 1.6 0.019 15.2 1.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII90776.1 - 2.2 8.7 6.3 0.95 9.9 0.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Mit_KHE1 PF10173.4 KII90778.1 - 1.2e-05 25.3 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Zip PF02535.17 KII90779.1 - 1.3e-30 106.5 1.3 1.8e-30 106.0 0.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter mRNA_triPase PF02940.10 KII90780.1 - 2.2e-52 177.9 0.0 2.6e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain F-box-like PF12937.2 KII90781.1 - 2.4e-07 30.3 2.4 4.6e-07 29.4 1.7 1.5 1 1 0 1 1 1 1 F-box-like DUF4150 PF13665.1 KII90782.1 - 0.49 10.3 7.0 5.4 6.9 0.1 3.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4150) MIP PF00230.15 KII90783.1 - 4.3e-53 180.1 2.6 5e-53 179.8 1.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KII90783.1 - 0.14 11.8 4.1 0.24 11.0 0.9 2.6 3 1 0 3 3 3 0 PAP2 superfamily EamA PF00892.15 KII90783.1 - 2.3 8.2 10.9 0.098 12.7 0.5 3.1 3 1 1 4 4 4 0 EamA-like transporter family NTR2 PF15458.1 KII90784.1 - 3.1e-60 203.5 7.4 3.1e-60 203.5 5.1 2.3 3 0 0 3 3 3 1 Nineteen complex-related protein 2 GCFC PF07842.7 KII90784.1 - 0.022 14.1 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein Rad60-SLD PF11976.3 KII90785.1 - 4.2e-10 39.1 0.0 0.0039 16.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like PH PF00169.24 KII90787.1 - 0.012 15.8 0.3 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 PH domain SSrecog PF03531.9 KII90788.1 - 2.6e-77 259.1 0.0 4.5e-77 258.3 0.0 1.4 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KII90788.1 - 2.7e-25 88.1 0.1 6e-23 80.6 0.0 2.5 2 0 0 2 2 2 2 Histone chaperone Rttp106-like Cauli_VI PF01693.11 KII90793.1 - 2.7e-13 49.7 5.5 3.5e-09 36.5 0.1 3.2 3 0 0 3 3 3 3 Caulimovirus viroplasmin PNPase_C PF12111.3 KII90793.1 - 0.19 10.9 1.6 0.52 9.5 1.1 1.8 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal zf-B_box PF00643.19 KII90795.1 - 0.00023 21.0 4.7 0.00071 19.4 3.3 1.9 1 0 0 1 1 1 1 B-box zinc finger CH PF00307.26 KII90796.1 - 1.5e-42 144.0 0.0 2.9e-24 85.2 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Cofilin_ADF PF00241.15 KII90796.1 - 2.1e-40 137.5 1.4 5.6e-40 136.1 0.3 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein EFhand_Ca_insen PF08726.5 KII90796.1 - 4.7e-16 58.5 0.3 2.6e-14 52.9 0.0 3.6 3 1 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KII90796.1 - 1.1e-13 50.6 0.1 1.1e-10 40.9 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Seryl_tRNA_N PF02403.17 KII90796.1 - 0.00041 20.3 0.5 0.0016 18.4 0.3 2.0 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain EF-hand_6 PF13405.1 KII90796.1 - 0.0074 16.0 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 KII90796.1 - 0.032 14.5 7.1 0.1 12.8 1.5 3.2 2 1 0 2 2 2 0 Spectrin repeat EF-hand_8 PF13833.1 KII90796.1 - 0.044 13.3 0.5 8 6.1 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain pair TroA PF01297.12 KII90796.1 - 0.07 12.3 0.5 0.23 10.6 0.3 1.9 1 0 0 1 1 1 0 Periplasmic solute binding protein family EF-hand_7 PF13499.1 KII90796.1 - 0.09 12.9 0.1 0.32 11.1 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair DASH_Duo1 PF08651.5 KII90796.1 - 0.21 11.1 2.2 1.7 8.3 0.2 2.8 1 1 0 2 2 2 0 DASH complex subunit Duo1 CENP-F_leu_zip PF10473.4 KII90796.1 - 0.35 10.7 3.6 0.84 9.4 2.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3407 PF11887.3 KII90796.1 - 0.49 9.6 1.8 0.59 9.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) DUF4404 PF14357.1 KII90796.1 - 1 9.7 4.9 4.7 7.7 2.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Apolipoprotein PF01442.13 KII90796.1 - 2.1 7.7 10.7 31 4.0 7.5 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.5 KII90796.1 - 2.2 8.4 6.2 1.6 8.8 0.8 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 KII90796.1 - 3.3 7.9 8.7 2 8.5 0.7 3.3 1 1 1 2 2 2 0 Syntaxin Porin_3 PF01459.17 KII90797.1 - 1e-63 215.2 0.1 1.1e-63 215.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin TPR_11 PF13414.1 KII90798.1 - 2.5e-21 75.1 1.3 1.3e-15 56.8 0.2 2.3 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 KII90798.1 - 4e-20 71.5 0.3 8.6e-20 70.5 0.1 1.6 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 KII90798.1 - 4.8e-16 57.5 1.1 9.8e-06 24.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII90798.1 - 1.9e-11 42.9 2.8 0.0048 16.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII90798.1 - 2.4e-11 43.9 3.0 7.8e-08 32.8 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII90798.1 - 3.5e-08 33.6 2.2 5.7e-06 26.5 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII90798.1 - 5.8e-06 26.0 0.2 0.033 14.0 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KII90798.1 - 1.1e-05 25.2 0.5 0.11 12.3 0.1 2.4 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KII90798.1 - 4e-05 23.8 3.6 0.46 11.2 0.1 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII90798.1 - 0.00019 20.9 0.7 0.36 10.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII90798.1 - 0.0046 16.8 2.4 0.069 13.0 0.7 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KII90798.1 - 0.006 16.6 0.3 0.02 15.0 0.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TAF1_subA PF14929.1 KII90798.1 - 0.0084 14.6 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_8 PF13181.1 KII90798.1 - 0.009 15.7 0.4 5.9 6.9 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 KII90798.1 - 0.029 13.4 0.8 1.2 8.0 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 KII90798.1 - 0.031 14.5 0.6 0.073 13.3 0.4 1.6 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_17 PF13431.1 KII90798.1 - 0.039 14.1 1.2 0.64 10.3 0.1 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 KII90798.1 - 0.08 13.0 1.1 3 8.0 0.5 2.9 3 1 1 4 4 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KII90798.1 - 0.14 12.4 0.4 18 5.5 0.0 2.4 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation MIT PF04212.13 KII90798.1 - 0.2 11.5 2.2 5.2 7.0 0.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KII90798.1 - 0.21 12.1 1.8 69 4.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF605 PF04652.11 KII90798.1 - 0.23 10.8 11.9 0.32 10.3 8.2 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 KII90799.1 - 1.4e-26 91.3 23.1 4.3e-09 35.9 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 KII90799.1 - 4.3e-26 91.5 0.0 8.7e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KII90799.1 - 3.7e-13 49.2 0.0 8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 KII90799.1 - 3e-06 25.6 0.6 0.0032 15.6 0.5 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DUF1470 PF07336.6 KII90800.1 - 0.023 15.0 2.3 0.048 14.0 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Prefoldin PF02996.12 KII90801.1 - 0.022 14.3 0.0 0.023 14.3 0.0 1.0 1 0 0 1 1 1 0 Prefoldin subunit F-box-like PF12937.2 KII90802.1 - 3.6e-09 36.1 0.7 4.1e-08 32.8 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII90802.1 - 0.045 13.4 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 F-box domain Mon1 PF03164.9 KII90803.1 - 1.3e-101 340.2 0.0 1.7e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-MYND PF01753.13 KII90804.1 - 1.7e-09 37.3 14.3 2.6e-09 36.7 9.9 1.3 1 0 0 1 1 1 1 MYND finger DUF2960 PF11173.3 KII90804.1 - 0.069 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) MFS_1 PF07690.11 KII90805.1 - 5.9e-19 67.9 44.3 1.2e-18 67.0 30.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRAM_LAG1_CLN8 PF03798.11 KII90806.1 - 9.1e-31 106.9 27.6 9.1e-31 106.9 19.1 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KII90806.1 - 7e-13 47.8 1.3 9.4e-13 47.4 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein DUF2561 PF10812.3 KII90807.1 - 0.026 14.1 0.6 0.048 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) H_PPase PF03030.11 KII90807.1 - 0.27 9.4 3.4 0.39 8.9 2.3 1.2 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase TraL PF07178.6 KII90807.1 - 0.53 10.3 4.4 0.42 10.6 0.5 2.6 1 1 1 2 2 2 0 TraL protein Glyco_hydro_43 PF04616.9 KII90808.1 - 4.9e-43 147.2 4.2 5.9e-43 146.9 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Flagellin_D3 PF08884.6 KII90808.1 - 0.33 11.1 3.7 12 6.2 0.0 2.7 3 0 0 3 3 3 0 Flagellin D3 domain ADH_N PF08240.7 KII90809.1 - 7.5e-27 93.2 0.4 1.4e-26 92.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII90809.1 - 3e-05 23.5 0.0 5.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_9 PF13454.1 KII90809.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding NADH_4Fe-4S PF10589.4 KII90809.1 - 3.7 6.7 6.8 13 5.0 4.7 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region IGR PF09597.5 KII90810.1 - 3.3e-14 52.5 0.0 4.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif BTB PF00651.26 KII90811.1 - 2.4e-06 27.4 0.0 6.2e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KII90812.1 - 2.7e-06 27.3 1.9 0.014 15.6 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII90812.1 - 1.1e-05 25.4 3.7 0.023 14.9 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type YL1 PF05764.8 KII90812.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.0 1 1 1 2 2 2 0 YL1 nuclear protein zf-H2C2_5 PF13909.1 KII90812.1 - 0.51 10.6 3.8 0.43 10.9 1.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KII90812.1 - 1.5 9.2 7.2 2.8 8.4 0.0 3.1 4 0 0 4 4 4 0 Zinc-finger double domain FHA PF00498.21 KII90813.1 - 3.3e-15 55.9 0.0 5.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 KII90813.1 - 4.3 5.6 26.0 5.3 5.4 18.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF566 PF04484.7 KII90813.1 - 9.3 5.6 11.1 12 5.2 7.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ole-e-6 PF09253.5 KII90815.1 - 0.11 12.1 0.5 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Pollen allergen ole e 6 Glyco_hydro_16 PF00722.16 KII90816.1 - 5.9e-05 22.4 0.2 0.0001 21.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GIT_SHD PF08518.6 KII90818.1 - 4.5e-16 57.9 0.1 2.3e-09 36.4 0.1 2.2 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT X PF00739.14 KII90819.1 - 3 7.7 7.2 1.9 8.4 3.4 1.9 1 1 2 3 3 3 0 Trans-activation protein X DEAD PF00270.24 KII90823.1 - 2.8e-14 52.9 0.2 7.6e-14 51.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII90823.1 - 5e-08 32.7 1.0 8.4e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII90823.1 - 7.2e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 KII90823.1 - 0.062 13.7 11.1 1.4 9.3 7.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_zinc_N PF00107.21 KII90824.1 - 5.2e-30 103.6 0.2 8.2e-30 103.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII90824.1 - 1.2e-12 48.8 0.1 3.9e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII90824.1 - 1.8e-10 40.5 0.3 6.7e-09 35.4 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Helicase_RecD PF05127.9 KII90824.1 - 0.11 12.0 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Helicase Abhydrolase_6 PF12697.2 KII90826.1 - 1.6e-11 44.5 1.7 2.1e-11 44.1 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII90826.1 - 7e-10 38.8 0.1 9.5e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII90826.1 - 1.2e-05 24.6 0.2 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1749 PF08538.5 KII90826.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 KII90826.1 - 0.012 15.2 0.4 0.031 13.8 0.2 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 KII90826.1 - 0.039 13.4 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ribosomal_L1 PF00687.16 KII90828.1 - 5.3e-52 176.3 0.1 7.1e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_M64 PF09471.5 KII90829.1 - 4.4e-29 101.9 0.0 6.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 Pkinase PF00069.20 KII90830.1 - 1.3e-70 237.5 0.0 2.1e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90830.1 - 3.7e-51 173.6 0.0 6.6e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII90830.1 - 0.0019 17.1 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Ribosomal_L5_C PF00673.16 KII90831.1 - 2.2e-14 52.9 0.0 5.9e-14 51.5 0.0 1.7 1 1 0 1 1 1 1 ribosomal L5P family C-terminus DHHA1 PF02272.14 KII90831.1 - 0.1 12.3 0.4 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 DHHA1 domain FGF-BP1 PF06473.7 KII90832.1 - 4.4 6.8 5.1 8.6 5.8 3.6 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Zn_clus PF00172.13 KII90833.1 - 5.1e-08 32.6 10.5 1.3e-07 31.4 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII90833.1 - 0.056 12.3 3.9 0.2 10.4 1.8 2.2 1 1 1 2 2 2 0 Fungal specific transcription factor domain Dynamin_N PF00350.18 KII90834.1 - 1e-17 64.4 0.5 3.4e-17 62.7 0.0 2.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KII90834.1 - 3.5e-11 43.0 0.0 1.8e-10 40.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KII90834.1 - 2.2e-10 40.2 0.0 1.6e-09 37.5 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KII90834.1 - 0.00018 22.0 0.1 0.0089 16.5 0.1 2.6 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 KII90834.1 - 0.002 17.5 0.2 0.18 11.2 0.0 2.7 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KII90834.1 - 0.0069 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.8 KII90834.1 - 0.018 13.9 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.16 KII90834.1 - 0.02 14.1 0.6 8.2 5.6 0.1 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family Septin PF00735.13 KII90834.1 - 0.093 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin DUF4341 PF14241.1 KII90834.1 - 0.11 12.1 0.7 0.73 9.5 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) PPTA PF01239.17 KII90835.1 - 3.5e-14 51.4 7.5 1.2e-07 30.7 0.1 5.6 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat DUF1212 PF06738.7 KII90835.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Zip PF02535.17 KII90838.1 - 0.15 11.0 1.3 0.18 10.7 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Aminotran_5 PF00266.14 KII90839.1 - 3.7e-14 52.2 0.0 6.7e-08 31.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 KII90839.1 - 1.8e-05 23.8 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KII90839.1 - 8.4e-05 21.7 0.1 0.0083 15.2 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3767 PF12597.3 KII90840.1 - 4e-19 68.4 0.0 4.5e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF865 PF05906.6 KII90840.1 - 0.24 10.9 3.0 0.52 9.9 2.1 1.6 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Glyco_hydro_18 PF00704.23 KII90841.1 - 2.4e-59 201.5 3.2 7.4e-59 199.9 2.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KII90841.1 - 0.053 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Pol_alpha_B_N PF08418.5 KII90842.1 - 2.1e-30 106.1 0.2 5.1e-16 58.9 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KII90842.1 - 2.2e-30 105.4 0.3 3e-30 105.0 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ORC2 PF04084.9 KII90843.1 - 1e-72 244.7 0.0 1.3e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MIP PF00230.15 KII90844.1 - 3.9e-53 180.2 7.5 4.7e-53 179.9 5.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KII90844.1 - 0.29 10.8 8.5 0.18 11.4 3.0 2.8 3 1 0 3 3 3 0 PAP2 superfamily EamA PF00892.15 KII90844.1 - 4.7 7.2 8.1 0.34 10.9 0.6 2.6 3 0 0 3 3 3 0 EamA-like transporter family NMO PF03060.10 KII90845.1 - 7.4e-62 209.4 0.1 9.2e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KII90845.1 - 6.6e-09 35.1 0.1 0.00013 20.9 0.5 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KII90845.1 - 0.0002 20.3 0.7 0.00029 19.7 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 KII90845.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 KII90845.1 - 0.032 13.3 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Glu_synthase PF01645.12 KII90845.1 - 0.12 11.2 1.4 0.26 10.1 0.8 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase DPBB_1 PF03330.13 KII90846.1 - 5.2e-06 26.3 0.0 9.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII90846.1 - 0.0083 15.7 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Barwin family Cyt-b5 PF00173.23 KII90847.1 - 1.6e-17 63.0 0.0 2.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LUC7 PF03194.10 KII90848.1 - 0.0042 16.6 0.7 0.0057 16.2 0.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus zf-MYND PF01753.13 KII90849.1 - 1e-08 34.8 9.0 1.8e-08 34.0 6.3 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KII90849.1 - 0.57 9.5 5.3 1.1 8.5 3.7 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Tcp11 PF05794.8 KII90850.1 - 8.9e-45 153.1 0.0 3.2e-44 151.3 0.0 1.9 1 1 0 1 1 1 1 T-complex protein 11 ATP-synt_ab PF00006.20 KII90852.1 - 8.4e-62 208.4 0.0 1.1e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KII90852.1 - 8.1e-17 61.7 0.0 1.6e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KII90852.1 - 2.4e-11 43.6 0.6 4.4e-11 42.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KII90852.1 - 0.00078 19.3 0.3 0.0019 18.0 0.2 1.6 1 0 0 1 1 1 1 HAS barrel domain TFCD_C PF12612.3 KII90853.1 - 5e-35 120.6 0.0 1.6e-33 115.8 0.0 3.0 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 KII90853.1 - 5.6e-05 23.3 16.5 0.0037 17.4 0.0 6.1 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.17 KII90853.1 - 0.0043 17.0 14.8 0.023 14.7 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat FliG_N PF14842.1 KII90853.1 - 0.1 12.7 0.0 0.41 10.7 0.0 2.0 1 0 0 1 1 1 0 FliG N-terminal domain HEAT_EZ PF13513.1 KII90853.1 - 0.11 13.0 0.1 0.11 13.0 0.0 7.6 7 1 1 8 8 8 0 HEAT-like repeat BUD22 PF09073.5 KII90854.1 - 1.2e-62 212.4 20.5 1.4e-62 212.2 14.2 1.1 1 0 0 1 1 1 1 BUD22 ER-remodelling PF14755.1 KII90854.1 - 6.3 6.8 17.3 0.17 11.9 1.7 3.2 3 0 0 3 3 3 0 Intracellular membrane remodeller PP2C PF00481.16 KII90856.1 - 3.5e-79 265.8 0.0 5.1e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KII90856.1 - 7e-05 22.3 0.0 0.0002 20.8 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KII90856.1 - 0.0091 15.7 0.2 0.26 10.9 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) CS PF04969.11 KII90857.1 - 3.9e-07 30.5 0.0 2.7e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 CS domain DUF2213 PF09979.4 KII90857.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Aldo_ket_red PF00248.16 KII90858.1 - 6.4e-52 176.1 0.0 7.2e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lactamase_B PF00753.22 KII90861.1 - 7.8e-11 41.9 1.7 1.2e-10 41.3 1.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KII90861.1 - 2.4e-05 23.9 0.1 3.7e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.2 KII90862.1 - 5.1e-08 32.5 0.8 1.5e-06 27.8 0.6 2.6 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KII90862.1 - 0.041 13.5 0.4 0.088 12.5 0.3 1.8 1 1 0 1 1 1 0 F-box-like domain Oxidored_FMN PF00724.15 KII90863.1 - 1.6e-94 316.7 0.0 1.8e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1637 PF07847.7 KII90864.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) Sugar_tr PF00083.19 KII90865.1 - 2.9e-106 355.7 21.7 3.3e-106 355.5 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII90865.1 - 7.3e-23 80.8 32.0 2.7e-17 62.5 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII90865.1 - 3e-05 22.6 1.1 3e-05 22.6 0.7 3.4 2 1 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KII90865.1 - 9.5e-05 21.2 2.8 0.00013 20.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 KII90865.1 - 0.0001 20.7 0.9 0.0001 20.7 0.6 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_61 PF03443.9 KII90867.1 - 1.8e-70 237.1 0.1 2.3e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Kdo PF06293.9 KII90869.1 - 2.9e-06 26.4 0.0 4.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KII90869.1 - 2.2e-05 23.7 0.0 9.1e-05 21.7 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 KII90869.1 - 0.0005 19.4 0.0 0.0013 18.1 0.0 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KII90869.1 - 0.0016 18.2 1.8 0.071 12.8 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family WD40 PF00400.27 KII90872.1 - 7.9e-165 529.6 61.4 7.8e-13 47.7 0.4 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat DUF3312 PF11768.3 KII90872.1 - 4.6e-15 54.8 0.1 0.061 11.5 0.0 7.5 3 2 4 8 8 8 7 Protein of unknown function (DUF3312) PD40 PF07676.7 KII90872.1 - 3.8e-13 48.7 18.4 5 6.8 0.0 12.8 14 0 0 14 14 14 2 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 KII90872.1 - 3.5e-12 46.0 4.7 7.8 6.3 0.0 11.3 10 3 2 12 12 12 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KII90872.1 - 1.6e-10 39.8 23.4 0.11 10.6 0.1 9.3 1 1 7 8 8 8 6 Nucleoporin Nup120/160 DUF1258 PF06869.7 KII90872.1 - 6.3e-05 22.1 7.6 21 4.1 0.0 7.4 3 3 8 11 11 11 0 Protein of unknown function (DUF1258) PQQ_3 PF13570.1 KII90872.1 - 0.0041 17.3 9.1 11 6.3 0.0 6.9 6 3 2 8 8 7 1 PQQ-like domain DUF1652 PF07865.6 KII90872.1 - 0.015 14.8 0.0 42 3.8 0.0 5.4 7 0 0 7 7 7 0 Protein of unknown function (DUF1652) IKI3 PF04762.7 KII90872.1 - 0.016 13.0 0.6 5.6 4.6 0.0 4.0 2 2 2 4 4 4 0 IKI3 family DUF1938 PF09153.5 KII90872.1 - 0.022 14.5 0.0 16 5.3 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF1938) Resistin PF06954.6 KII90872.1 - 0.044 14.0 0.0 2.5e+02 2.0 0.0 4.7 4 1 1 5 5 5 0 Resistin Hira PF07569.6 KII90872.1 - 1.6 7.8 5.7 1.1 8.4 0.2 3.3 4 0 0 4 4 4 0 TUP1-like enhancer of split NACHT PF05729.7 KII90873.1 - 5.3e-06 26.1 0.1 9.5e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 KII90873.1 - 0.00069 19.8 0.1 0.0037 17.4 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII90873.1 - 0.00074 19.5 0.1 0.0017 18.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII90873.1 - 0.00086 19.4 0.0 0.0016 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII90873.1 - 0.016 14.9 0.1 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KII90873.1 - 0.018 13.8 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 KII90873.1 - 0.022 13.7 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KII90873.1 - 0.023 13.9 0.4 0.041 13.1 0.3 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 KII90873.1 - 0.035 13.8 0.0 5.2 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KII90873.1 - 0.052 12.5 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.17 KII90873.1 - 0.091 12.1 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KII90873.1 - 0.091 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KII90873.1 - 0.12 11.7 0.4 1.9 7.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KII90873.1 - 0.13 12.1 0.0 4.7 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Calc_CGRP_IAPP PF00214.14 KII90875.1 - 0.047 13.7 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family TBCA PF02970.11 KII90876.1 - 0.03 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A HhH-GPD PF00730.20 KII90877.1 - 1.8e-11 44.2 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KII90877.1 - 0.0082 15.7 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KII90877.1 - 0.029 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Carb_kinase PF01256.12 KII90877.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase adh_short PF00106.20 KII90878.1 - 2.6e-13 50.2 0.2 3.9e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII90878.1 - 1.9e-05 24.4 0.2 2.9e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KII90878.1 - 0.011 15.8 0.2 0.018 15.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KII90878.1 - 0.027 14.2 0.1 0.071 12.9 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-DHHC PF01529.15 KII90880.1 - 1.3e-32 112.5 12.7 2.8e-32 111.4 8.6 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF912 PF06024.7 KII90880.1 - 0.047 13.7 0.6 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DZR PF12773.2 KII90880.1 - 0.062 13.1 2.9 0.13 12.1 2.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon Spt4 PF06093.8 KII90880.1 - 0.75 9.7 3.4 1.4 8.8 2.4 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Fungal_trans PF04082.13 KII90881.1 - 0.00033 19.5 0.0 0.00052 18.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII90881.1 - 0.00062 19.6 1.8 0.0012 18.7 1.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.18 KII90882.1 - 6e-56 189.8 31.1 2.5e-29 102.5 5.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII90882.1 - 2.2e-52 176.9 0.0 3.9e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII90882.1 - 2.6e-10 39.8 3.2 0.0015 17.8 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII90882.1 - 2.2e-09 37.6 0.1 0.026 14.5 0.0 3.6 3 1 1 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 KII90882.1 - 2.5e-08 33.8 0.2 0.011 15.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KII90882.1 - 4.4e-07 30.3 0.1 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KII90882.1 - 7.1e-07 28.6 0.3 0.053 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KII90882.1 - 1.8e-06 27.8 0.1 0.0051 16.6 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.1 KII90882.1 - 3.5e-06 27.1 0.6 0.059 13.3 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KII90882.1 - 8.7e-06 25.2 0.0 0.018 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KII90882.1 - 1.6e-05 24.1 0.4 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KII90882.1 - 3.4e-05 24.0 0.5 0.11 12.6 0.1 3.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KII90882.1 - 3.7e-05 23.2 0.1 0.047 13.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KII90882.1 - 0.00012 22.9 0.0 0.41 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KII90882.1 - 0.00012 22.4 0.2 0.19 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KII90882.1 - 0.00014 21.0 0.5 0.22 10.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 KII90882.1 - 0.0015 18.8 0.1 2.7 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KII90882.1 - 0.0023 17.6 0.5 1.4 8.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KII90882.1 - 0.0026 17.6 2.1 0.5 10.1 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 ArgK PF03308.11 KII90882.1 - 0.007 15.1 0.6 2.5 6.7 0.0 2.3 2 0 0 2 2 2 2 ArgK protein ATP-synt_ab PF00006.20 KII90882.1 - 0.0081 15.6 0.1 2.4 7.6 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KII90882.1 - 0.0083 15.7 0.5 5.2 6.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KII90882.1 - 0.01 14.7 0.7 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 KII90882.1 - 0.011 14.8 0.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 KII90882.1 - 0.017 14.5 0.3 4.9 6.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KII90882.1 - 0.017 13.9 0.0 5.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 KII90882.1 - 0.018 13.6 0.3 1.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KII90882.1 - 0.018 14.4 1.4 4.4 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KII90882.1 - 0.018 15.1 0.0 15 5.8 0.0 3.3 4 0 0 4 4 2 0 RNA helicase NACHT PF05729.7 KII90882.1 - 0.024 14.3 0.4 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KII90882.1 - 0.028 14.1 0.1 1.4 8.5 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KII90882.1 - 0.038 13.4 0.2 6.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KII90882.1 - 0.077 12.9 0.1 4.9 7.1 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 KII90882.1 - 0.085 11.4 0.5 48 2.3 0.0 3.7 4 0 0 4 4 4 0 Predicted ATPase of the ABC class NB-ARC PF00931.17 KII90882.1 - 0.16 10.8 1.3 12 4.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.9 KII90882.1 - 0.2 10.6 0.0 7.8 5.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain UPF0079 PF02367.12 KII90882.1 - 0.55 9.8 1.9 16 5.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DNA_pol_A_exo1 PF01612.15 KII90883.1 - 2.8e-44 150.6 0.1 4.5e-44 150.0 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KII90883.1 - 3.3e-14 52.9 2.1 1.3e-13 51.0 0.7 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KII90883.1 - 3.7e-13 48.9 0.1 1.4e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 HRDC domain H-K_ATPase_N PF09040.6 KII90883.1 - 0.0062 16.6 0.2 2.3 8.4 0.0 3.4 3 0 0 3 3 3 1 Gastric H+/K+-ATPase, N terminal domain Velvet PF11754.3 KII90885.1 - 2.5e-44 151.3 0.8 4.5e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 Velvet factor DEAD PF00270.24 KII90888.1 - 1.2e-11 44.4 0.0 2.3e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 KII90888.1 - 0.15 10.6 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 KII90888.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SKN1 PF03935.10 KII90889.1 - 2.1e-189 629.8 2.5 2.5e-189 629.6 1.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Avl9 PF09794.4 KII90891.1 - 6.1e-130 433.0 0.0 7.6e-130 432.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KII90891.1 - 6e-09 35.6 0.0 0.0034 17.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KII90891.1 - 5e-08 32.5 3.2 0.00034 19.9 1.1 2.9 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Drc1-Sld2 PF11719.3 KII90892.1 - 0.0062 15.6 2.2 0.0084 15.2 1.5 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Acetyltransf_3 PF13302.1 KII90893.1 - 1.2e-11 44.9 0.0 1.6e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII90893.1 - 0.00037 20.4 0.0 0.00072 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Cullin PF00888.17 KII90894.1 - 4.7e-45 154.2 0.0 9.5e-45 153.2 0.0 1.4 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 KII90894.1 - 1.5e-09 37.9 0.0 3.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 GDC-P PF02347.11 KII90894.1 - 0.12 10.9 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Glycine cleavage system P-protein Pkinase PF00069.20 KII90899.1 - 2.5e-61 207.1 0.0 3.5e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII90899.1 - 4.9e-34 117.5 0.0 2.2e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KII90899.1 - 9.2e-05 21.5 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KII90899.1 - 0.0012 17.7 0.4 0.0031 16.3 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 DUF1215 PF06744.7 KII90899.1 - 0.089 12.4 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) TMF_DNA_bd PF12329.3 KII90901.1 - 0.0023 17.6 15.6 0.094 12.5 5.9 3.2 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 KII90901.1 - 0.0033 17.6 0.9 0.21 11.8 0.1 3.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 KII90901.1 - 0.034 14.5 10.8 0.12 12.8 0.5 3.8 2 1 0 3 3 3 0 SlyX AAA_13 PF13166.1 KII90901.1 - 0.32 9.4 10.1 0.44 8.9 7.0 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 KII90901.1 - 0.39 9.0 13.9 0.031 12.6 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Peptidase_S46 PF10459.4 KII90901.1 - 0.59 8.4 7.2 0.78 8.0 5.0 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2959 PF11172.3 KII90901.1 - 0.76 9.5 10.0 0.87 9.3 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Spc24 PF08286.6 KII90901.1 - 1.8 8.3 13.5 2.9 7.6 0.1 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Bacillus_HBL PF05791.6 KII90901.1 - 2 7.7 8.0 0.67 9.2 3.0 2.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.4 KII90901.1 - 2.1 8.5 7.3 0.61 10.2 1.3 2.6 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KII90901.1 - 2.3 7.3 5.3 5.2 6.1 1.8 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 KII90901.1 - 2.8 6.7 16.8 3.6 6.4 11.1 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3829 PF12889.2 KII90901.1 - 3 6.9 9.2 1.3 8.1 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Macoilin PF09726.4 KII90901.1 - 3.8 5.6 17.6 7.2 4.7 12.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Syntaxin-6_N PF09177.6 KII90901.1 - 8 6.9 11.5 9.9 6.6 1.9 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ABC_tran_2 PF12848.2 KII90901.1 - 8.9 6.2 13.8 7.1 6.5 8.1 1.9 2 0 0 2 2 2 0 ABC transporter SNF2_N PF00176.18 KII90902.1 - 7.3e-73 244.9 0.0 9.6e-73 244.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII90902.1 - 3.6e-14 52.3 0.0 1.5e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII90902.1 - 1.6e-07 30.9 0.0 1.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KII90902.1 - 0.00071 19.4 0.0 0.0028 17.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3105 PF11303.3 KII90902.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) zf-C3HC4 PF00097.20 KII90908.1 - 8.2e-09 34.9 1.3 8.2e-09 34.9 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII90908.1 - 1.5e-08 34.4 2.8 1.5e-08 34.4 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII90908.1 - 2.1e-07 30.7 2.8 2.1e-07 30.7 2.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KII90908.1 - 4.6e-07 29.5 11.9 4.6e-07 29.5 6.8 2.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KII90908.1 - 6e-06 25.8 0.6 6e-06 25.8 0.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KII90908.1 - 9.2e-06 25.2 3.8 0.00024 20.6 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KII90908.1 - 6.7e-05 22.5 0.3 6.7e-05 22.5 0.2 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KII90908.1 - 0.0039 16.8 11.3 0.036 13.8 7.8 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 KII90908.1 - 0.0097 15.4 6.9 0.026 14.0 1.3 2.4 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KII90908.1 - 0.011 15.2 2.4 0.025 14.1 1.5 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KII90908.1 - 0.014 15.4 7.0 0.02 14.9 2.2 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger Myb_DNA-bind_4 PF13837.1 KII90908.1 - 0.031 14.4 0.2 0.062 13.4 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-Apc11 PF12861.2 KII90908.1 - 0.11 12.3 1.8 0.43 10.4 0.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger F-box PF00646.28 KII90910.1 - 0.061 12.9 1.2 0.13 11.9 0.1 2.2 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KII90910.1 - 0.071 12.8 0.3 0.25 11.0 0.1 2.1 3 0 0 3 3 3 0 F-box-like GST_N PF02798.15 KII90912.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KII90912.1 - 3.7e-08 33.4 0.0 7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII90912.1 - 1.7e-07 31.0 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KII90912.1 - 4.9e-06 26.4 0.0 7.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII90912.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dynamin_N PF00350.18 KII90913.1 - 6.7e-15 55.3 0.0 1.7e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KII90913.1 - 6.7e-06 26.0 0.1 0.0067 16.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.11 KII90913.1 - 0.00031 19.9 0.3 0.0026 16.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 KII90913.1 - 0.00045 20.5 0.2 0.0076 16.5 0.0 2.6 3 0 0 3 3 3 1 ABC transporter Miro PF08477.8 KII90913.1 - 0.0026 18.2 0.1 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 KII90913.1 - 0.0033 17.2 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF87 IIGP PF05049.8 KII90913.1 - 0.0099 14.7 0.0 0.52 9.0 0.0 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 KII90913.1 - 0.013 14.6 0.0 0.036 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KII90913.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KII90913.1 - 0.026 13.9 0.0 0.062 12.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KII90913.1 - 0.13 11.7 0.3 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SMC_N PF02463.14 KII90913.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Sad1_UNC PF07738.8 KII90916.1 - 2.6e-22 79.0 0.0 5.5e-22 78.0 0.0 1.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Pico_P2A PF00947.14 KII90917.1 - 0.014 15.2 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Picornavirus core protein 2A zf-C3HC4 PF00097.20 KII90918.1 - 7.7e-06 25.4 2.0 1.4e-05 24.6 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII90918.1 - 2.3e-05 24.0 5.4 3.6e-05 23.3 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII90918.1 - 4.3e-05 23.2 2.3 8.9e-05 22.2 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII90918.1 - 0.00016 21.4 1.6 0.00036 20.3 1.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KII90918.1 - 0.00018 21.4 3.7 0.00037 20.4 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII90918.1 - 0.00055 19.6 3.9 0.00062 19.4 1.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KII90918.1 - 0.0014 18.2 4.4 0.0021 17.6 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) EZH2_WD-Binding PF11616.3 KII90918.1 - 0.0024 17.7 0.1 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 WD repeat binding protein EZH2 zf-Apc11 PF12861.2 KII90918.1 - 0.0056 16.4 0.5 0.0088 15.8 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FTA4 PF13093.1 KII90918.1 - 0.015 14.7 0.3 0.02 14.3 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 zf-RING_4 PF14570.1 KII90918.1 - 0.02 14.4 0.6 0.041 13.4 0.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tho2 PF11262.3 KII90918.1 - 0.04 12.9 0.4 0.052 12.5 0.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 KII90918.1 - 0.04 13.4 1.4 0.051 13.1 1.0 1.2 1 0 0 1 1 1 0 IncA protein WbqC PF08889.6 KII90918.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 WbqC-like protein family FYVE PF01363.16 KII90918.1 - 0.13 12.1 2.9 0.37 10.7 2.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_6 PF14835.1 KII90918.1 - 0.16 11.7 2.0 0.32 10.8 1.4 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KII90918.1 - 0.26 11.4 3.0 0.47 10.5 2.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger IBR PF01485.16 KII90918.1 - 0.33 10.8 2.4 0.44 10.4 0.9 1.9 1 1 0 1 1 1 0 IBR domain DUF2235 PF09994.4 KII90919.1 - 2e-78 263.5 0.0 2.5e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KII90919.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3850 PF12961.2 KII90919.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) MFS_1 PF07690.11 KII90920.1 - 2.5e-18 65.9 64.0 4.1e-16 58.6 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily N_methyl PF07963.7 KII90920.1 - 0.095 12.4 0.5 0.095 12.4 0.3 2.8 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation motif A_deaminase PF00962.17 KII90921.1 - 3e-109 364.9 0.3 4.1e-109 364.4 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Snf7 PF03357.16 KII90922.1 - 0.12 11.7 5.1 0.13 11.5 3.6 1.1 1 0 0 1 1 1 0 Snf7 DUF4226 PF10774.4 KII90922.1 - 0.29 11.1 5.5 0.33 11.0 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DUF3153 PF11353.3 KII90922.1 - 0.29 10.5 2.0 0.28 10.6 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF3407 PF11887.3 KII90922.1 - 0.61 9.3 2.5 0.67 9.1 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) DUF484 PF04340.7 KII90922.1 - 0.65 9.4 5.5 0.68 9.3 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF484 APG6 PF04111.7 KII90922.1 - 1.4 7.8 7.1 1.5 7.7 4.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinetocho_Slk19 PF12709.2 KII90922.1 - 1.5 8.9 6.2 1.9 8.6 0.4 2.0 1 1 1 2 2 2 0 Central kinetochore-associated TMF_DNA_bd PF12329.3 KII90922.1 - 1.6 8.5 11.0 2.2 8.1 3.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 KII90922.1 - 2 8.4 7.8 3.5 7.6 4.8 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 ADIP PF11559.3 KII90922.1 - 2.1 8.2 8.3 2.4 8.0 5.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 KII90922.1 - 3.1 6.1 6.1 2.9 6.2 4.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.7 KII90922.1 - 5.8 7.3 9.4 57 4.1 6.5 2.0 1 1 0 1 1 1 0 SlyX DivIC PF04977.10 KII90922.1 - 7.3 6.1 9.3 4.8 6.7 2.3 2.1 1 1 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KII90923.1 - 3.5e-05 23.4 5.4 4.2e-05 23.2 3.7 1.0 1 0 0 1 1 1 1 IncA protein EzrA PF06160.7 KII90923.1 - 0.0017 16.6 2.6 0.002 16.4 1.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_27 PF13514.1 KII90923.1 - 0.002 15.9 2.7 0.0022 15.7 1.9 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 KII90923.1 - 0.0025 16.5 8.3 0.003 16.2 5.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3552 PF12072.3 KII90923.1 - 0.0049 16.0 6.2 0.0062 15.7 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) V_ATPase_I PF01496.14 KII90923.1 - 0.0055 14.6 5.7 0.0063 14.4 3.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4201 PF13870.1 KII90923.1 - 0.0056 16.1 7.2 0.0072 15.7 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) ATG16 PF08614.6 KII90923.1 - 0.0091 15.8 5.1 0.013 15.3 3.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Amidoligase_2 PF12224.3 KII90923.1 - 0.079 12.5 0.3 0.087 12.4 0.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme Syntaxin PF00804.20 KII90923.1 - 0.091 12.9 6.0 0.13 12.4 4.2 1.4 1 0 0 1 1 1 0 Syntaxin Microtub_assoc PF07989.6 KII90923.1 - 0.11 12.3 3.3 1.6 8.6 0.5 2.7 2 1 1 3 3 3 0 Microtubule associated COG5 PF10392.4 KII90923.1 - 0.12 12.3 5.4 0.26 11.2 3.7 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Laminin_II PF06009.7 KII90923.1 - 0.13 12.0 6.2 0.23 11.1 3.8 1.6 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 KII90923.1 - 0.13 12.5 4.6 0.79 10.0 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.8 KII90923.1 - 0.13 10.6 1.0 0.18 10.1 0.7 1.3 1 0 0 1 1 1 0 Tweety DUF2514 PF10721.4 KII90923.1 - 0.17 11.5 2.4 0.19 11.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Atg14 PF10186.4 KII90923.1 - 0.19 10.6 6.8 0.22 10.4 4.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 KII90923.1 - 0.27 11.0 4.6 6.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.6 KII90923.1 - 0.39 10.7 4.9 0.58 10.1 3.4 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Phage_GP20 PF06810.6 KII90923.1 - 0.82 9.1 6.8 0.23 10.9 0.5 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF16 PF01519.11 KII90923.1 - 0.93 9.7 6.8 1.8 8.8 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 YgaB PF14182.1 KII90923.1 - 1.1 9.4 8.8 3.5 7.9 2.7 2.3 1 1 1 2 2 2 0 YgaB-like protein DUF1515 PF07439.6 KII90923.1 - 1.3 8.9 5.4 1.3 8.8 2.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) F-box-like PF12937.2 KII90924.1 - 0.0013 18.3 0.0 0.0041 16.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KII90924.1 - 0.025 14.3 0.1 2.5 7.9 0.0 3.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 KII90924.1 - 0.027 14.0 1.1 7 6.3 0.0 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KII90924.1 - 0.094 12.8 1.3 54 4.3 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat DUF4283 PF14111.1 KII90926.1 - 0.0053 15.8 0.2 0.0088 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4283) WD40 PF00400.27 KII90927.1 - 1.6e-16 59.4 0.9 2.1e-10 40.0 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KII90927.1 - 0.0006 19.3 0.0 0.006 16.0 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain Kelch_4 PF13418.1 KII90927.1 - 0.11 12.2 0.0 0.4 10.5 0.0 2.0 1 0 0 1 1 1 0 Galactose oxidase, central domain Transposase_21 PF02992.9 KII90928.1 - 4.5e-12 45.5 0.0 7.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 tRNA_deacylase PF04414.7 KII90929.1 - 0.00078 18.6 0.1 0.0021 17.2 0.0 1.6 2 0 0 2 2 2 1 D-aminoacyl-tRNA deacylase JmjC PF02373.17 KII90929.1 - 0.0021 18.2 0.4 0.008 16.4 0.3 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Mito_carr PF00153.22 KII90930.1 - 1.3e-49 165.8 4.0 2.6e-17 62.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AMPKBI PF04739.10 KII90931.1 - 4.3e-22 77.8 1.9 4.5e-22 77.7 0.0 2.0 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DEAD PF00270.24 KII90932.1 - 1.9e-21 76.3 0.0 3.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII90932.1 - 1.4e-16 60.0 0.0 8.9e-14 51.1 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KII90932.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain CN_hydrolase PF00795.17 KII90933.1 - 4e-07 29.5 0.0 5.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_3 PF07859.8 KII90934.1 - 5.7e-17 62.0 0.1 1.2e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII90934.1 - 2.1e-13 50.2 0.0 8.2e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII90934.1 - 4.8e-08 32.4 0.1 0.00042 19.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KII90934.1 - 1.4e-07 31.6 2.7 2.5e-07 30.8 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KII90934.1 - 0.00033 19.9 0.1 0.079 12.2 0.0 2.7 2 1 1 3 3 3 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KII90934.1 - 0.00045 19.7 0.0 0.0049 16.3 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.23 KII90934.1 - 0.13 10.9 0.1 1.4 7.5 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S15 PF02129.13 KII90934.1 - 0.15 11.4 0.1 0.55 9.5 0.0 2.2 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PAS_3 PF08447.6 KII90935.1 - 3.8e-06 26.9 0.0 8.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KII90935.1 - 9.1e-05 22.2 0.0 0.0003 20.5 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KII90935.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 KII90935.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_11 PF14598.1 KII90935.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain GCD14 PF08704.5 KII90936.1 - 8.2e-91 303.8 0.6 3.7e-89 298.4 0.4 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KII90936.1 - 9.4e-06 25.3 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KII90936.1 - 1.3e-05 25.1 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII90936.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII90936.1 - 0.00023 21.7 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KII90936.1 - 0.0017 19.1 0.1 0.0039 17.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 KII90936.1 - 0.036 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_23 PF13489.1 KII90936.1 - 0.051 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KII90936.1 - 0.089 11.8 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KII90936.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KII90936.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain BHD_3 PF10405.4 KII90937.1 - 1.9e-28 97.9 0.0 4.4e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KII90937.1 - 2.7e-21 75.5 0.0 4e-20 71.6 0.0 2.4 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KII90937.1 - 1.6e-15 56.3 0.0 3.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KII90937.1 - 2.3e-11 43.8 0.8 8.3e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KII90937.1 - 4.8e-07 29.9 0.2 5.7e-06 26.5 0.1 2.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily FYRC PF05965.9 KII90938.1 - 1.5e-16 59.9 0.0 4.4e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 KII90938.1 - 2.1e-15 55.8 0.3 4.4e-15 54.8 0.2 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Spt20 PF12090.3 KII90938.1 - 0.0018 17.6 3.8 0.0018 17.6 0.3 2.3 2 0 0 2 2 2 1 Spt20 family DUF4658 PF15555.1 KII90938.1 - 1.3 8.8 8.0 0.21 11.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) DUF972 PF06156.8 KII90938.1 - 9.8 6.5 10.4 1.1 9.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4064 PF13273.1 KII90939.1 - 0.004 17.2 0.7 2.2 8.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) DUF2407_C PF13373.1 KII90939.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Claudin_2 PF13903.1 KII90939.1 - 0.033 13.8 2.4 0.22 11.1 0.5 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3112 PF11309.3 KII90939.1 - 0.22 11.3 2.4 0.93 9.2 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Tetraspannin PF00335.15 KII90939.1 - 0.41 9.8 3.4 1.2 8.3 1.2 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF1240 PF06836.7 KII90939.1 - 0.51 10.5 0.1 0.51 10.5 0.1 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1240) DUF202 PF02656.10 KII90940.1 - 2.7e-18 65.9 0.9 2.7e-18 65.9 0.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Asp PF00026.18 KII90941.1 - 3.4e-23 82.3 6.5 4.7e-21 75.3 4.5 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII90941.1 - 0.0018 18.7 1.6 0.009 16.4 0.3 2.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 KII90941.1 - 0.016 15.1 1.0 0.36 10.7 0.7 2.5 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal BTB PF00651.26 KII90942.1 - 1.5e-05 24.9 0.0 3.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.13 KII90943.1 - 8.6e-32 110.0 0.0 1.6e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII90943.1 - 1.3e-06 28.1 11.3 2.6e-06 27.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Usp PF00582.21 KII90944.1 - 2.4e-20 73.1 0.1 2.4e-20 73.1 0.1 2.2 2 0 0 2 2 2 1 Universal stress protein family Asp PF00026.18 KII90945.1 - 1.4e-19 70.4 0.2 1.4e-16 60.6 0.1 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Shisa PF13908.1 KII90945.1 - 3.4e-05 24.0 0.2 5.3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Asp_protease_2 PF13650.1 KII90945.1 - 0.004 17.6 1.5 0.41 11.1 0.8 2.8 2 0 0 2 2 2 1 Aspartyl protease Herpes_gE PF02480.11 KII90945.1 - 0.0097 14.2 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KII90945.1 - 0.16 11.3 4.3 0.31 10.3 3.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain p450 PF00067.17 KII90946.1 - 5.5e-69 232.8 0.0 1e-68 231.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.16 KII90947.1 - 3.1e-59 200.3 0.0 4.7e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII90947.1 - 1.1e-52 178.7 0.1 1.7e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII90947.1 - 2.4e-19 69.0 0.5 4.7e-19 68.0 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AAA PF00004.24 KII90950.1 - 3.9e-41 140.3 0.0 9.6e-41 139.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII90950.1 - 2.2e-05 24.5 0.1 0.0018 18.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII90950.1 - 0.00035 20.7 1.0 0.018 15.1 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KII90950.1 - 0.00063 19.6 0.0 0.0077 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KII90950.1 - 0.0007 18.7 0.0 0.0015 17.6 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KII90950.1 - 0.00078 19.1 0.3 0.008 15.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 KII90950.1 - 0.0017 17.6 0.1 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 KII90950.1 - 0.0041 17.0 0.1 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KII90950.1 - 0.0063 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KII90950.1 - 0.0067 16.1 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KII90950.1 - 0.0085 15.2 0.1 0.034 13.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KII90950.1 - 0.012 16.4 0.1 0.033 15.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KII90950.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KII90950.1 - 0.037 13.4 1.2 0.45 9.8 0.1 2.4 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KII90950.1 - 0.06 12.2 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KII90950.1 - 0.084 12.4 0.4 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KII90950.1 - 0.15 11.6 0.3 3.1 7.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain NuA4 PF09340.5 KII90951.1 - 5.1e-24 83.7 0.1 5.1e-24 83.7 0.1 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Snf7 PF03357.16 KII90951.1 - 0.047 13.0 0.2 0.047 13.0 0.1 1.4 2 0 0 2 2 2 0 Snf7 Mod_r PF07200.8 KII90953.1 - 4.1e-21 75.4 7.2 5.3e-20 71.8 5.0 1.9 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.1 KII90953.1 - 0.00091 19.2 3.5 0.00091 19.2 2.4 1.9 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF2051 PF09738.4 KII90953.1 - 0.011 15.1 0.2 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) CSTF2_hinge PF14327.1 KII90953.1 - 0.04 13.9 0.6 0.21 11.6 0.5 2.1 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Glyco_hydro_61 PF03443.9 KII90954.1 - 5.5e-50 170.1 0.0 6.5e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DNA_pol_B PF00136.16 KII90956.1 - 1.3e-93 314.3 0.0 1.9e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KII90956.1 - 2.8e-20 72.4 0.0 1.7e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KII90956.1 - 1.8e-15 56.6 2.3 3.4e-15 55.7 1.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 KII90956.1 - 0.21 10.2 0.1 0.34 9.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Oxidored_FMN PF00724.15 KII90957.1 - 3.1e-94 315.7 0.0 3.6e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NCA2 PF08637.5 KII90958.1 - 1.2e-72 244.2 0.0 2.6e-72 243.1 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 DUF221 PF02714.10 KII90959.1 - 3.8e-103 344.7 22.2 6.1e-103 344.0 15.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KII90959.1 - 3.3e-34 117.7 6.3 3.3e-34 117.7 4.4 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KII90959.1 - 1e-13 51.6 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KII90959.1 - 3e-13 49.4 0.1 1.7e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein Oxidored_FMN PF00724.15 KII90960.1 - 9.6e-100 333.8 0.0 1.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DXP_reductoisom PF02670.11 KII90961.1 - 0.065 13.7 0.0 0.089 13.3 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cyclin_N PF00134.18 KII90962.1 - 1.2e-12 47.4 0.0 1e-11 44.5 0.0 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain MBOAT_2 PF13813.1 KII90963.1 - 1.7e-09 37.6 8.2 1.7e-09 37.6 5.7 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family adh_short PF00106.20 KII90965.1 - 4e-23 82.1 0.9 1.3e-22 80.5 0.1 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KII90965.1 - 8.6e-11 41.8 0.1 2.3e-10 40.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KII90965.1 - 1.2e-07 31.4 0.1 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KII90965.1 - 4.8e-07 29.7 0.0 7.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII90965.1 - 7.4e-05 22.8 0.2 0.00021 21.3 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KII90965.1 - 0.00088 18.3 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 KII90965.1 - 0.044 13.0 0.2 0.066 12.4 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 KII90965.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TIR-like PF10137.4 KII90965.1 - 0.13 11.8 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NAD_binding_4 PF07993.7 KII90965.1 - 0.16 10.8 0.3 0.28 10.0 0.2 1.5 1 1 0 1 1 1 0 Male sterility protein CDC37_N PF03234.9 KII90966.1 - 7e-49 166.5 1.2 9.1e-49 166.1 0.2 1.6 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KII90966.1 - 2.5e-32 111.7 0.1 6.7e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KII90966.1 - 6.2e-18 64.4 0.4 5.5e-17 61.4 0.0 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain PgaD PF13994.1 KII90967.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 PgaD-like protein DUF1180 PF06679.7 KII90967.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Endomucin PF07010.7 KII90967.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Endomucin Rifin_STEVOR PF02009.11 KII90967.1 - 0.22 11.1 0.1 0.29 10.7 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family GWT1 PF06423.7 KII90968.1 - 4.6 7.3 12.8 45 4.1 8.9 2.3 1 1 0 1 1 1 0 GWT1 DUF3624 PF12292.3 KII90968.1 - 5.3 7.5 11.0 0.47 10.8 2.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) Zip PF02535.17 KII90969.1 - 0.38 9.6 5.0 0.48 9.3 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ni_hydr_CYTB PF01292.15 KII90970.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SCIMP PF15050.1 KII90970.1 - 0.035 14.0 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein SRF-TF PF00319.13 KII90971.1 - 2.5e-23 81.0 0.2 3.3e-23 80.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-C3H1 PF10650.4 KII90972.1 - 0.0014 18.1 0.2 0.0023 17.3 0.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain adh_short PF00106.20 KII90974.1 - 3.4e-20 72.6 0.1 6.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII90974.1 - 4.5e-08 32.9 0.1 8.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII90974.1 - 0.00018 21.3 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII90974.1 - 0.00019 20.9 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII90974.1 - 0.0013 18.7 0.1 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII90974.1 - 0.023 13.4 0.3 0.042 12.5 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldo_ket_red PF00248.16 KII90975.1 - 1.2e-62 211.3 0.0 1.3e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KII90976.1 - 1.4e-21 77.1 0.0 4.4e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII90976.1 - 1.1e-09 38.2 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII90976.1 - 5.2e-06 26.0 0.1 1e-05 25.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII90976.1 - 8.5e-06 25.8 0.3 1.3e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KII90976.1 - 2.6e-05 24.1 0.0 8.1e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KII90976.1 - 0.0024 17.9 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KII90976.1 - 0.0037 16.2 0.2 0.0053 15.7 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 KII90976.1 - 0.034 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 KII90976.1 - 0.035 13.3 0.3 0.055 12.7 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_7 PF13241.1 KII90976.1 - 0.11 12.7 0.1 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding VWA_2 PF13519.1 KII90978.1 - 5.5e-09 36.3 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KII90978.1 - 1.2e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 KII90978.1 - 0.0039 16.2 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Miro PF08477.8 KII90979.1 - 1.5e-35 122.2 0.0 3.8e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KII90979.1 - 3.5e-33 113.2 0.0 8.6e-33 111.9 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KII90979.1 - 1.7e-30 105.5 0.0 3.6e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 KII90979.1 - 3.4e-30 103.1 0.5 6.8e-30 102.1 0.3 1.5 1 0 0 1 1 1 1 EF hand associated Arf PF00025.16 KII90979.1 - 5.8e-10 38.6 0.0 0.00022 20.5 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.1 KII90979.1 - 1.5e-08 33.8 1.8 0.0018 17.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain AAA_22 PF13401.1 KII90979.1 - 5.7e-08 32.9 0.0 0.0073 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KII90979.1 - 7.9e-08 32.2 0.0 0.0006 19.7 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 KII90979.1 - 2.5e-07 29.5 3.5 0.0015 17.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KII90979.1 - 8.9e-07 27.9 5.0 0.0017 17.6 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 KII90979.1 - 2.3e-06 27.7 0.1 0.074 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_7 PF13499.1 KII90979.1 - 3.6e-06 27.0 0.9 0.0091 16.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_28 PF13521.1 KII90979.1 - 4e-06 26.9 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KII90979.1 - 1.7e-05 24.5 0.1 0.096 12.3 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KII90979.1 - 4.6e-05 22.8 0.0 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KII90979.1 - 4.7e-05 23.7 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.1 KII90979.1 - 5.5e-05 22.8 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KII90979.1 - 0.00011 22.4 0.0 0.27 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KII90979.1 - 0.00012 22.3 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KII90979.1 - 0.00015 21.6 1.0 0.46 10.2 0.1 3.1 2 1 1 3 3 3 1 Dynamin family NACHT PF05729.7 KII90979.1 - 0.00017 21.2 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SRPRB PF09439.5 KII90979.1 - 0.00052 19.2 0.1 0.37 9.9 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 KII90979.1 - 0.00056 19.7 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KII90979.1 - 0.00056 19.4 0.0 0.18 11.3 0.0 2.7 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KII90979.1 - 0.00057 19.1 0.0 0.1 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KII90979.1 - 0.0012 19.6 0.0 1.8 9.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain ATP_bind_1 PF03029.12 KII90979.1 - 0.0012 18.3 3.1 5.3 6.5 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KII90979.1 - 0.0019 18.3 0.0 0.73 10.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Septin PF00735.13 KII90979.1 - 0.0021 17.1 0.0 0.055 12.4 0.0 2.2 2 0 0 2 2 2 1 Septin DUF815 PF05673.8 KII90979.1 - 0.0025 16.8 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 KII90979.1 - 0.0026 17.2 0.0 1.7 8.0 0.0 3.7 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KII90979.1 - 0.003 17.0 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family G-alpha PF00503.15 KII90979.1 - 0.0045 15.7 0.0 1.8 7.1 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit AAA_5 PF07728.9 KII90979.1 - 0.0098 15.6 0.0 0.31 10.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KII90979.1 - 0.011 15.2 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KII90979.1 - 0.011 15.2 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KII90979.1 - 0.018 14.7 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KII90979.1 - 0.022 15.0 0.1 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 KII90979.1 - 0.03 13.7 0.2 2.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E AAA_14 PF13173.1 KII90979.1 - 0.035 14.0 0.0 9.6 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KII90979.1 - 0.042 12.7 0.0 4.9 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain EF-hand_10 PF14788.1 KII90979.1 - 0.045 13.4 0.1 0.045 13.4 0.1 2.0 2 0 0 2 2 1 0 EF hand cobW PF02492.14 KII90979.1 - 0.047 13.1 0.1 2.5 7.5 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 KII90979.1 - 0.049 12.4 0.1 0.25 10.0 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family Sigma54_activat PF00158.21 KII90979.1 - 0.053 12.9 0.0 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 KII90979.1 - 0.057 12.9 0.0 0.21 11.0 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AIG1 PF04548.11 KII90979.1 - 0.076 12.1 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 1 0 AIG1 family SPARC_Ca_bdg PF10591.4 KII90979.1 - 0.086 12.8 1.3 1.9 8.5 0.0 2.6 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region Guanylate_kin PF00625.16 KII90979.1 - 0.13 11.6 0.1 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.7 KII90979.1 - 0.13 11.2 0.0 7.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 KII90979.1 - 0.16 11.6 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KII90979.1 - 0.18 11.3 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KII90979.1 - 0.21 10.1 0.0 13 4.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain zf-RVT PF13966.1 KII90980.1 - 1.8e-05 24.9 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_C48 PF02902.14 KII90983.1 - 6.2e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Inhibitor_I29 PF08246.7 KII90985.1 - 0.014 15.6 0.4 0.81 10.0 0.0 2.6 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Baculo_PEP_C PF04513.7 KII90985.1 - 0.02 14.7 1.2 0.079 12.7 0.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.2 KII90986.1 - 2.2e-08 33.7 0.5 6.8e-08 32.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like DUF2773 PF10971.3 KII90986.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) p450 PF00067.17 KII90987.1 - 8.9e-69 232.1 0.0 2e-68 231.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KII90988.1 - 0.00016 21.3 0.2 0.00037 20.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII90988.1 - 0.01 15.4 0.3 0.01 15.4 0.2 1.9 2 0 0 2 2 2 0 F-box domain RCC1_2 PF13540.1 KII90988.1 - 0.077 12.6 0.3 0.077 12.6 0.2 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 KII90988.1 - 1.9 8.4 8.5 27 4.8 0.1 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat RasGEF PF00617.14 KII90989.1 - 4.6e-51 173.2 0.0 7.2e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII90989.1 - 1.2e-19 70.2 0.0 4.2e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KII90989.1 - 1.3e-13 50.2 0.0 3.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII90989.1 - 6.5e-13 47.9 0.0 2.2e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII90989.1 - 7.8e-11 41.1 0.0 1.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Methyltransf_11 PF08241.7 KII90991.1 - 7.8e-11 42.3 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII90991.1 - 3.9e-09 36.7 0.0 7.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII90991.1 - 1.7e-08 35.0 0.0 3.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII90991.1 - 2e-08 34.2 0.0 5.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII90991.1 - 3.5e-08 33.3 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII90991.1 - 4.5e-07 29.2 0.0 7.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KII90991.1 - 2e-06 27.4 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII90991.1 - 1.8e-05 25.1 0.0 4.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KII90991.1 - 0.00027 19.3 0.0 0.00064 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 KII90991.1 - 0.0095 15.0 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KII90991.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.13 KII90991.1 - 0.044 12.9 0.1 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase FtsJ PF01728.14 KII90991.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase FmrO PF07091.6 KII90991.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) LRR_4 PF12799.2 KII90992.1 - 0.00023 20.7 0.0 0.68 9.6 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KII90992.1 - 0.0035 17.2 0.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeat F-box-like PF12937.2 KII90992.1 - 0.051 13.3 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like LRR_1 PF00560.28 KII90992.1 - 0.053 13.5 0.0 3.5 8.0 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Clat_adaptor_s PF01217.15 KII90993.1 - 1.1e-56 190.5 3.5 1.2e-56 190.4 2.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ArfGap PF01412.13 KII90994.1 - 1.2e-33 115.3 0.3 1.2e-33 115.3 0.2 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CytochromB561_N PF09786.4 KII90994.1 - 0.34 9.2 3.1 0.46 8.8 2.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Med3 PF11593.3 KII90994.1 - 6.1 5.9 8.4 8.6 5.4 5.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UQ_con PF00179.21 KII90998.1 - 4e-41 139.7 0.0 5e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KII90998.1 - 5.5e-19 67.5 0.9 5.5e-19 67.5 0.6 1.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KII90998.1 - 0.00055 19.7 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.9 KII90998.1 - 0.015 15.2 0.1 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 FeoA domain Chitin_synth_2 PF03142.10 KII90999.1 - 1.3e-13 50.1 1.4 1.9e-12 46.3 0.0 2.8 3 0 0 3 3 3 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 KII90999.1 - 5.3e-13 49.2 0.3 3.9e-08 33.3 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KII90999.1 - 1.2e-07 31.6 8.9 1.2e-07 31.6 6.2 3.4 1 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KII90999.1 - 1.1e-05 25.2 0.0 0.041 13.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KII90999.1 - 0.0001 21.6 0.1 0.00019 20.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF3778 PF12620.3 KII90999.1 - 0.0043 16.5 0.1 0.02 14.4 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3778) Coprogen_oxidas PF01218.13 KII91000.1 - 1.5e-117 391.3 0.0 2e-117 390.9 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glycos_transf_3 PF00591.16 KII91001.1 - 1.8e-77 260.2 0.0 2.2e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KII91001.1 - 4.3e-07 29.4 0.0 7.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF633 PF04816.7 KII91001.1 - 0.04 13.2 0.2 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Pro-kuma_activ PF09286.6 KII91002.1 - 2.8e-44 150.6 0.1 6.7e-43 146.1 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII91002.1 - 6.8e-06 25.4 2.7 1.1e-05 24.8 1.8 1.3 1 0 0 1 1 1 1 Subtilase family Nop14 PF04147.7 KII91003.1 - 0.42 8.4 8.3 0.59 7.9 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KII91003.1 - 0.6 9.1 11.9 0.95 8.4 8.3 1.2 1 0 0 1 1 1 0 BUD22 HTH_29 PF13551.1 KII91004.1 - 9.2e-06 25.7 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_33 PF13592.1 KII91004.1 - 0.034 13.6 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 KII91004.1 - 0.046 13.3 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain ALAD PF00490.16 KII91005.1 - 0.085 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Helicase_C PF00271.26 KII91007.1 - 2e-14 53.1 0.0 5.1e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII91007.1 - 8.1e-12 44.9 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC_6 PF15288.1 KII91007.1 - 0.00051 19.6 1.7 0.0015 18.1 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle T4SS-DNA_transf PF02534.9 KII91007.1 - 0.0052 15.4 0.0 0.0089 14.6 0.0 1.3 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 KII91007.1 - 0.18 11.6 0.1 0.61 9.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RPAP1_C PF08620.5 KII91008.1 - 4.2e-20 71.3 0.0 8.9e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KII91008.1 - 1.7e-07 30.7 4.5 4.1e-07 29.4 3.1 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF763 PF05559.6 KII91008.1 - 0.35 9.7 0.1 0.81 8.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Gly-zipper_Omp PF13488.1 KII91009.1 - 0.018 14.6 39.3 0.07 12.7 11.9 3.4 2 1 1 3 3 3 0 Glycine zipper DUF4169 PF13770.1 KII91009.1 - 0.15 12.0 2.5 0.18 11.7 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4169) CsbD PF05532.7 KII91009.1 - 0.34 10.6 4.3 1.8 8.2 3.0 2.3 1 1 0 1 1 1 0 CsbD-like GSH_synth_ATP PF03917.12 KII91010.1 - 2.2e-90 302.9 0.0 2.9e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KII91010.1 - 3.6e-31 107.3 0.0 5.5e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SWI-SNF_Ssr4 PF08549.5 KII91012.1 - 1.5e-11 43.3 7.9 9.4e-08 30.8 0.0 2.3 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1750) CG-1 PF03859.11 KII91012.1 - 0.06 12.8 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 CG-1 domain DivIC PF04977.10 KII91012.1 - 0.47 9.9 2.9 2.9 7.4 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Amino_oxidase PF01593.19 KII91013.1 - 5.1e-32 111.5 0.0 3.1e-31 108.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII91013.1 - 2.3e-10 40.3 0.0 6.1e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII91013.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII91013.1 - 0.0087 14.5 0.1 0.023 13.1 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KII91013.1 - 0.025 13.6 0.1 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 KII91013.1 - 0.054 13.0 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KII91013.1 - 0.062 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII91013.1 - 0.15 10.9 0.3 0.25 10.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KII91013.1 - 0.28 9.9 0.1 0.48 9.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Gly-zipper_OmpA PF13436.1 KII91015.1 - 0.052 13.2 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Cation_efflux PF01545.16 KII91016.1 - 1.7e-31 109.3 4.2 2e-31 109.1 2.9 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1049 PF06305.6 KII91016.1 - 0.011 15.1 0.5 0.13 11.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TMEMspv1-c74-12 PF11044.3 KII91016.1 - 0.053 13.0 0.3 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein BPL_LplA_LipB PF03099.14 KII91016.1 - 0.058 13.4 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family VSP PF03302.8 KII91017.1 - 0.083 11.5 0.3 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein MLANA PF14991.1 KII91018.1 - 0.0064 16.4 0.1 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein melan-A Pkinase PF00069.20 KII91019.1 - 2.1e-42 145.0 0.0 6.8e-31 107.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII91019.1 - 1.4e-25 89.8 0.0 4.1e-21 75.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII91019.1 - 0.00012 21.1 0.0 0.37 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KII91019.1 - 0.015 14.9 0.2 0.05 13.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Antimicrobial18 PF08130.6 KII91019.1 - 0.093 12.6 0.2 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Type A lantibiotic family Macro PF01661.16 KII91020.1 - 3.4e-17 62.4 0.1 4.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Macro domain Proteasome PF00227.21 KII91023.1 - 1.3e-32 112.6 0.0 1.5e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.4 KII91024.1 - 6.5e-59 198.8 0.9 7.4e-59 198.6 0.6 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal OPT PF03169.10 KII91025.1 - 8e-199 662.1 64.0 9.1e-199 661.9 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein UPF0233 PF06781.7 KII91025.1 - 0.07 12.7 6.1 0.3 10.7 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) YcbB PF08664.5 KII91026.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 YcbB domain HisG PF01634.13 KII91027.1 - 2.8e-49 166.8 0.1 4.8e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KII91027.1 - 5.5e-27 93.5 0.0 1.5e-26 92.0 0.0 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.6 KII91027.1 - 8.8e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Methyltransf_20 PF12147.3 KII91027.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase SLAC1 PF03595.12 KII91028.1 - 8.5e-51 172.5 44.2 9.8e-51 172.3 30.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3366 PF11846.3 KII91028.1 - 0.45 10.3 2.9 1.4 8.7 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) HIT PF01230.18 KII91029.1 - 7.6e-25 87.3 0.1 9.8e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KII91029.1 - 4.4e-11 43.0 0.0 6.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KII91029.1 - 0.0014 18.2 0.6 0.0026 17.4 0.4 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DIOX_N PF14226.1 KII91030.1 - 1.9e-29 102.5 0.0 3.3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII91030.1 - 1e-18 67.4 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1081 PF06448.6 KII91030.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Peptidase_M3 PF01432.15 KII91031.1 - 6.7e-134 447.3 0.0 9.3e-134 446.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KII91031.1 - 0.0036 16.6 0.1 0.0064 15.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase M50B-like TAT_signal PF10518.4 KII91031.1 - 0.19 11.8 0.6 0.55 10.3 0.4 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF814 PF05670.8 KII91035.1 - 6.1e-23 80.5 0.0 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) ALMS_motif PF15309.1 KII91035.1 - 0.73 9.6 12.0 1.2 9.0 8.3 1.2 1 0 0 1 1 1 0 ALMS motif RRM_1 PF00076.17 KII91036.1 - 3.8e-10 39.2 0.0 2e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII91036.1 - 0.00021 21.2 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KII91036.1 - 0.0016 18.4 0.2 0.0035 17.4 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KII91036.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COesterase PF00135.23 KII91038.1 - 3.3e-104 349.5 0.0 7.7e-104 348.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII91038.1 - 8.4e-06 25.5 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII91038.1 - 0.019 14.2 1.0 0.11 11.7 0.9 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family Amino_oxidase PF01593.19 KII91039.1 - 1.5e-30 106.6 0.0 2.1e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII91039.1 - 3.1e-09 36.7 0.0 8e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII91039.1 - 0.0068 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII91039.1 - 0.029 12.8 0.0 0.23 9.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 KII91039.1 - 0.048 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Peroxidase_2 PF01328.12 KII91040.1 - 1.3e-22 79.9 0.0 2.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 FAD_binding_3 PF01494.14 KII91041.1 - 7.7e-71 239.0 0.0 1.1e-70 238.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KII91041.1 - 1.9e-06 26.9 0.2 1.6e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KII91041.1 - 7.1e-06 25.9 0.1 2.9e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII91041.1 - 7.9e-06 25.8 0.1 2.2e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII91041.1 - 9.2e-06 24.3 0.3 7.5e-05 21.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KII91041.1 - 1.3e-05 25.3 0.0 5.9e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII91041.1 - 4.2e-05 22.6 0.1 0.013 14.3 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII91041.1 - 0.00018 21.8 0.2 0.19 12.1 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII91041.1 - 0.00053 18.9 0.0 0.00086 18.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KII91041.1 - 0.00095 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KII91041.1 - 0.00098 18.2 0.0 0.0023 17.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII91041.1 - 0.0089 14.9 0.2 0.024 13.5 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KII91041.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KII91041.1 - 0.02 14.6 0.1 0.054 13.2 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KII91041.1 - 0.064 11.8 0.5 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 KII91041.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain AAA PF00004.24 KII91042.1 - 3.7e-38 130.7 0.0 6.6e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KII91042.1 - 1.7e-06 27.2 0.0 5.7e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KII91042.1 - 5.6e-06 26.5 0.1 0.00064 19.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 KII91042.1 - 9.7e-06 26.4 0.0 3.3e-05 24.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KII91042.1 - 2.6e-05 24.2 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KII91042.1 - 3.6e-05 23.8 0.0 0.00047 20.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KII91042.1 - 4.2e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KII91042.1 - 7.5e-05 22.4 0.3 0.00061 19.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KII91042.1 - 0.00013 21.0 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KII91042.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KII91042.1 - 0.00046 19.4 0.2 0.0013 17.9 0.1 1.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KII91042.1 - 0.0005 19.5 0.2 0.032 13.6 0.2 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KII91042.1 - 0.00051 19.5 0.1 0.00095 18.6 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KII91042.1 - 0.0007 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KII91042.1 - 0.00074 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KII91042.1 - 0.00088 19.2 0.1 0.0022 17.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 KII91042.1 - 0.0012 17.5 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 KII91042.1 - 0.0025 16.5 0.1 0.0041 15.8 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 KII91042.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KII91042.1 - 0.0029 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 KII91042.1 - 0.0032 17.1 0.0 0.036 13.7 0.0 2.2 2 1 0 2 2 1 1 Bacterial dnaA protein NACHT PF05729.7 KII91042.1 - 0.0037 16.9 0.1 0.0096 15.5 0.1 1.7 2 0 0 2 2 1 1 NACHT domain Sigma54_activat PF00158.21 KII91042.1 - 0.01 15.3 0.0 0.033 13.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KII91042.1 - 0.021 14.5 0.0 0.067 12.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 KII91042.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 KII91042.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KII91042.1 - 0.024 14.9 0.1 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KII91042.1 - 0.029 14.0 0.0 0.089 12.4 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase SKI PF01202.17 KII91042.1 - 0.04 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.6 KII91042.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KII91042.1 - 0.068 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 KII91042.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KII91042.1 - 0.083 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 KII91042.1 - 0.11 11.9 0.0 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase PhoH PF02562.11 KII91042.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATP-synt_ab PF00006.20 KII91042.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Glyco_hydro_20 PF00728.17 KII91043.1 - 8.2e-81 271.8 0.0 9.8e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KII91043.1 - 2.8e-12 47.4 0.0 3e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KII91043.1 - 8.8e-07 29.5 0.0 2.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_97 PF10566.4 KII91043.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 Glycos_transf_1 PF00534.15 KII91044.1 - 1e-23 83.6 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KII91044.1 - 3e-09 37.1 0.1 5.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DAO PF01266.19 KII91045.1 - 1.8e-38 132.3 0.7 8.1e-37 126.9 0.5 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII91045.1 - 0.0002 21.6 0.0 0.76 10.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII91045.1 - 0.001 18.8 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KII91045.1 - 0.0025 17.7 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII91045.1 - 0.0032 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII91045.1 - 0.0047 17.0 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KII91045.1 - 0.0086 15.1 0.1 0.84 8.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KII91045.1 - 0.14 10.7 0.0 6.3 5.3 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_M20 PF01546.23 KII91046.1 - 8.3e-29 100.4 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KII91046.1 - 8.8e-10 38.3 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KII91046.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 FMN_dh PF01070.13 KII91047.1 - 1.4e-112 376.1 0.0 1.7e-112 375.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 KII91047.1 - 3.8e-05 22.8 0.3 0.013 14.5 0.0 3.6 4 1 0 4 4 4 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KII91047.1 - 4.1e-05 22.6 0.7 0.00079 18.4 0.2 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KII91047.1 - 0.00013 20.9 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DEAD PF00270.24 KII91049.1 - 9.5e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 KII91049.1 - 0.076 11.5 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SUR7 PF06687.7 KII91051.1 - 7.8e-17 61.5 19.4 1.9e-16 60.2 13.5 1.6 1 1 0 1 1 1 1 SUR7/PalI family DuoxA PF10204.4 KII91051.1 - 0.097 11.7 7.7 0.024 13.7 1.9 1.9 2 0 0 2 2 2 0 Dual oxidase maturation factor Claudin_2 PF13903.1 KII91051.1 - 0.27 10.9 17.1 0.01 15.5 5.0 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 KII91051.1 - 1.5 8.7 11.8 0.066 13.0 2.8 2.5 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Pyr_redox_2 PF07992.9 KII91052.1 - 1.8e-29 103.0 0.0 2.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII91052.1 - 7.5e-19 67.9 0.1 1.5e-15 57.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII91052.1 - 5e-08 33.2 0.2 5.3e-05 23.3 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII91052.1 - 1.1e-06 27.7 0.5 0.0056 15.6 0.0 3.2 1 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KII91052.1 - 1.3e-05 24.4 0.1 0.00011 21.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KII91052.1 - 2.1e-05 24.4 0.3 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KII91052.1 - 6.5e-05 23.0 0.1 0.11 12.6 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KII91052.1 - 9e-05 21.4 0.5 0.0017 17.2 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KII91052.1 - 0.00034 20.8 0.1 0.04 14.1 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 KII91052.1 - 0.00035 19.5 5.3 0.0044 15.9 0.1 3.8 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII91052.1 - 0.00045 19.4 0.0 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KII91052.1 - 0.00049 19.1 0.1 0.28 10.0 0.0 3.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KII91052.1 - 0.0013 17.9 0.1 0.048 12.7 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KII91052.1 - 0.0021 16.6 0.5 0.039 12.4 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 KII91052.1 - 0.0045 15.6 0.4 0.05 12.2 0.2 2.5 2 1 1 3 3 3 1 Tryptophan halogenase F420_oxidored PF03807.12 KII91052.1 - 0.011 16.1 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KII91052.1 - 0.014 14.8 0.4 4.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KII91052.1 - 0.024 14.3 0.3 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 KII91052.1 - 0.025 14.3 0.1 7.4 6.3 0.1 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding IlvN PF07991.7 KII91052.1 - 0.047 13.0 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 KII91052.1 - 0.052 13.3 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 ThiF family ATP-synt_C PF00137.16 KII91053.1 - 2.7e-31 107.2 31.9 1.3e-18 66.6 9.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 KII91053.1 - 4.5 6.9 10.1 0.67 9.5 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Sad1_UNC PF07738.8 KII91054.1 - 8.7e-29 100.0 0.0 2.8e-28 98.3 0.0 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal WD40 PF00400.27 KII91056.1 - 1.1e-46 155.1 14.8 2.9e-11 42.7 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KII91056.1 - 0.0018 16.5 3.7 0.36 8.9 0.1 3.4 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII91056.1 - 0.054 12.2 0.9 1.2 7.8 0.0 3.2 1 1 1 3 3 3 0 Nup133 N terminal like CDC48_2 PF02933.12 KII91057.1 - 3.9e-06 26.4 0.1 0.3 10.7 0.0 4.2 2 1 2 4 4 4 3 Cell division protein 48 (CDC48), domain 2 DUF320 PF03777.8 KII91057.1 - 0.034 13.9 6.0 0.62 9.8 0.2 3.8 3 1 1 4 4 4 0 Small secreted domain (DUF320) Tetraspannin PF00335.15 KII91058.1 - 3.1e-15 56.0 9.0 4.1e-15 55.6 6.2 1.1 1 0 0 1 1 1 1 Tetraspanin family Peptidase_M3 PF01432.15 KII91059.1 - 2.4e-115 386.1 0.0 3.5e-115 385.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KII91059.1 - 0.053 12.8 0.6 0.092 12.1 0.4 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WD40 PF00400.27 KII91061.1 - 2.6e-07 30.2 0.2 0.011 15.5 0.0 6.4 7 0 0 7 7 7 1 WD domain, G-beta repeat Glyco_hydro_20 PF00728.17 KII91062.1 - 4.1e-78 262.9 0.0 2.2e-76 257.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KII91062.1 - 8.6e-14 52.2 0.0 2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KII91062.1 - 5.5e-07 30.1 0.0 2.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 UPF0150 PF03681.10 KII91062.1 - 0.12 12.0 0.1 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0150) Glyco_hydro_20 PF00728.17 KII91063.1 - 1.1e-90 304.3 0.0 1.3e-90 304.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KII91063.1 - 4.3e-15 56.5 0.0 9.9e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KII91063.1 - 7.8e-10 39.3 0.3 1.7e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 ENTH PF01417.15 KII91065.1 - 1.7e-44 150.6 0.1 2.4e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KII91065.1 - 0.029 13.0 0.1 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 ANTH domain RNA_pol_Rpb4 PF03874.11 KII91067.1 - 2.3e-22 79.1 0.4 3.1e-22 78.7 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.16 KII91067.1 - 0.022 14.8 0.4 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 Death effector domain NOT2_3_5 PF04153.13 KII91068.1 - 3e-33 114.5 1.3 8.1e-33 113.1 0.9 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Prenyltrans PF00432.16 KII91069.1 - 1.8e-33 113.7 8.9 1.8e-09 36.9 0.8 5.4 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KII91069.1 - 4.3e-24 85.0 0.0 1.9e-13 50.8 0.0 3.5 2 2 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KII91069.1 - 1.9e-06 27.8 0.0 0.025 14.6 0.0 3.1 3 0 0 3 3 3 2 Prenyltransferase-like DUF972 PF06156.8 KII91070.1 - 0.75 10.1 4.2 12 6.2 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KII91070.1 - 5.3 5.8 9.3 7.7 5.3 6.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 KII91071.1 - 2.9e-48 164.2 0.0 3.6e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91071.1 - 3.6e-29 101.6 0.0 4.2e-28 98.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII91071.1 - 0.00063 18.7 0.0 0.00096 18.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII91071.1 - 0.00096 18.9 0.5 0.003 17.3 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_8 PF13855.1 KII91072.1 - 0.00012 21.7 0.8 0.0011 18.6 0.3 2.9 2 1 0 2 2 2 1 Leucine rich repeat Pyr_redox_3 PF13738.1 KII91073.1 - 4.9e-23 82.2 0.0 2.5e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII91073.1 - 3.3e-17 61.9 0.2 7.3e-16 57.4 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KII91073.1 - 2.8e-13 49.5 0.8 1.1e-10 40.9 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII91073.1 - 1.7e-10 41.1 0.0 2.2e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII91073.1 - 1.1e-08 34.9 1.1 3.6e-08 33.3 0.0 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KII91073.1 - 0.0096 15.7 0.3 0.82 9.4 0.1 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KII91073.1 - 0.06 12.2 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GPI-anchored PF10342.4 KII91076.1 - 0.00093 19.6 0.2 0.0013 19.1 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PGAP1 PF07819.8 KII91077.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KII91077.1 - 0.0045 16.2 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF4640 PF15480.1 KII91077.1 - 0.017 14.7 2.0 0.034 13.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) ST7 PF04184.7 KII91077.1 - 2.7 6.1 4.9 6.6 4.8 2.4 1.9 2 0 0 2 2 2 0 ST7 protein Velvet PF11754.3 KII91078.1 - 2.5e-28 99.0 0.0 3.6e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Velvet factor ELFV_dehydrog PF00208.16 KII91079.1 - 2.4e-51 174.6 0.0 3.4e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KII91079.1 - 5.5e-18 63.9 0.0 6.3e-12 43.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KII91079.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SpoU_methylase PF00588.14 KII91079.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 SpoU rRNA Methylase family adh_short PF00106.20 KII91080.1 - 1e-29 103.6 0.4 1.3e-29 103.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII91080.1 - 5e-15 55.9 0.0 6.8e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII91080.1 - 2.9e-10 40.1 0.2 4.5e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KII91080.1 - 0.02 14.4 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 KII91080.1 - 0.024 14.3 0.8 0.037 13.6 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KII91080.1 - 0.024 14.6 0.3 0.055 13.4 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_2 PF07992.9 KII91080.1 - 0.026 14.4 0.2 5.7 6.7 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.5 KII91080.1 - 0.04 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Rossmann-like PF10727.4 KII91080.1 - 0.056 13.1 0.0 0.32 10.7 0.0 2.1 2 1 0 2 2 2 0 Rossmann-like domain Thi4 PF01946.12 KII91080.1 - 0.45 9.5 2.7 0.26 10.3 0.2 1.7 2 0 0 2 2 2 0 Thi4 family SAM_2 PF07647.12 KII91081.1 - 3.1e-09 36.5 0.0 8.1e-09 35.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KII91081.1 - 2.9e-06 27.3 0.1 7.2e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ALIX_LYPXL_bnd PF13949.1 KII91081.1 - 0.068 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV FAD_binding_7 PF03441.9 KII91082.1 - 5.2e-51 173.4 0.2 6.9e-51 173.0 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KII91082.1 - 9e-21 74.3 0.0 1.6e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Acetyltransf_3 PF13302.1 KII91083.1 - 4.9e-11 42.9 0.0 6.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII91083.1 - 0.00011 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Flavoprotein PF02441.14 KII91084.1 - 5.4e-43 145.7 0.0 6.7e-43 145.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DUF3605 PF12239.3 KII91085.1 - 1e-26 93.6 2.2 2e-10 40.7 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) Mob1_phocein PF03637.12 KII91086.1 - 1.1e-64 217.3 0.3 1.4e-64 216.9 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family TPR_MLP1_2 PF07926.7 KII91087.1 - 5.5e-18 64.9 17.1 5.5e-18 64.9 11.9 16.6 6 4 9 15 15 15 7 TPR/MLP1/MLP2-like protein LELP1 PF15042.1 KII91087.1 - 0.11 12.6 5.5 0.31 11.2 3.8 1.7 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Pkinase PF00069.20 KII91088.1 - 1.9e-44 151.7 0.0 3e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91088.1 - 5.8e-20 71.4 0.0 1.9e-19 69.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII91088.1 - 4.6e-06 25.7 0.0 8.7e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII91088.1 - 0.001 18.8 0.2 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC_tran PF00005.22 KII91089.1 - 4.9e-46 156.4 0.0 1.8e-27 96.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII91089.1 - 3.2e-36 125.1 29.9 2.4e-20 73.0 0.9 3.6 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 KII91089.1 - 6.7e-13 48.3 1.6 0.0034 16.6 0.2 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII91089.1 - 7.7e-11 42.4 1.7 0.015 15.2 0.1 4.3 2 2 1 3 3 3 3 AAA domain AAA_25 PF13481.1 KII91089.1 - 2e-08 33.8 0.0 0.0071 15.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KII91089.1 - 5.6e-06 26.8 1.6 0.00042 20.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII91089.1 - 1.8e-05 24.1 0.8 0.12 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KII91089.1 - 2.3e-05 23.9 0.3 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 KII91089.1 - 5.2e-05 23.3 1.8 0.23 11.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KII91089.1 - 5.5e-05 23.9 0.1 0.14 13.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 KII91089.1 - 8.6e-05 21.5 0.0 0.038 12.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KII91089.1 - 9.2e-05 22.5 0.2 0.071 13.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KII91089.1 - 0.00062 19.4 0.8 0.49 10.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KII91089.1 - 0.0018 18.2 0.1 0.43 10.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 KII91089.1 - 0.0018 18.1 2.7 0.041 13.7 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KII91089.1 - 0.0042 17.5 0.0 5 7.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 KII91089.1 - 0.0054 17.0 0.0 3.1 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KII91089.1 - 0.0064 15.6 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KII91089.1 - 0.0091 15.7 0.0 0.24 11.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KII91089.1 - 0.014 15.2 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 KII91089.1 - 0.015 14.7 0.4 4.3 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 KII91089.1 - 0.015 15.1 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KII91089.1 - 0.025 14.2 0.0 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase Pox_A32 PF04665.7 KII91089.1 - 0.033 13.5 0.9 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.24 KII91089.1 - 0.033 13.6 0.0 9.7 5.6 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KII91089.1 - 0.033 13.9 0.2 11 5.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KII91089.1 - 0.038 13.4 0.0 5.8 6.2 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 KII91089.1 - 0.085 12.3 0.1 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Adeno_IVa2 PF02456.10 KII91089.1 - 0.12 11.0 0.0 0.64 8.5 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_11 PF13086.1 KII91089.1 - 0.14 11.7 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.18 KII91089.1 - 0.32 10.8 1.9 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.1 KII91089.1 - 0.78 8.7 0.0 1.4 7.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 KII91090.1 - 4.8e-117 390.9 0.0 6e-117 390.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII91090.1 - 5e-10 38.8 0.3 9.2e-07 28.2 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII91090.1 - 0.0037 16.7 0.1 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KII91090.1 - 0.0056 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KII91090.1 - 0.011 15.1 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KII91090.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KII91090.1 - 0.097 11.7 0.1 2.1 7.3 0.0 2.5 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region Transferase PF02458.10 KII91091.1 - 5.8e-40 137.0 0.0 3e-15 55.6 0.0 3.0 3 0 0 3 3 3 3 Transferase family KRE9 PF05390.6 KII91091.1 - 0.029 14.7 0.6 0.084 13.2 0.4 1.8 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 DUF1886 PF09171.5 KII91091.1 - 0.12 11.3 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) AAA_5 PF07728.9 KII91092.1 - 1.2e-114 378.2 0.0 1e-20 73.9 0.0 9.4 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KII91092.1 - 2.1e-24 85.5 0.0 2.7e-07 30.2 0.0 7.9 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII91092.1 - 8.1e-23 80.9 0.8 0.0056 16.8 0.0 7.2 7 0 0 7 7 6 5 AAA domain AAA_16 PF13191.1 KII91092.1 - 8.5e-22 78.0 5.9 2.8e-05 24.1 0.0 7.1 6 0 0 6 6 6 3 AAA ATPase domain AAA PF00004.24 KII91092.1 - 2.4e-21 76.3 0.0 0.00027 21.1 0.0 5.9 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KII91092.1 - 3.2e-17 63.4 0.0 0.012 16.4 0.0 6.4 6 0 0 6 6 5 3 AAA domain AAA_18 PF13238.1 KII91092.1 - 6.7e-17 62.0 0.0 0.0077 16.5 0.0 5.7 5 0 0 5 5 5 3 AAA domain Sigma54_activat PF00158.21 KII91092.1 - 4.9e-15 55.4 0.0 0.0087 15.5 0.0 5.1 5 0 0 5 5 4 4 Sigma-54 interaction domain AAA_14 PF13173.1 KII91092.1 - 5.3e-15 55.4 0.0 0.0024 17.7 0.0 7.1 7 1 0 7 7 6 2 AAA domain Sigma54_activ_2 PF14532.1 KII91092.1 - 1.3e-14 54.4 0.1 0.00036 20.5 0.0 5.7 5 0 0 5 5 5 2 Sigma-54 interaction domain T2SE PF00437.15 KII91092.1 - 2.6e-13 49.5 0.1 0.0036 16.2 0.0 5.4 5 0 0 5 5 5 3 Type II/IV secretion system protein AAA_19 PF13245.1 KII91092.1 - 3e-12 46.0 8.3 0.0013 18.3 0.1 6.9 7 0 0 7 7 6 3 Part of AAA domain AAA_30 PF13604.1 KII91092.1 - 1.7e-10 40.7 0.2 0.00078 19.0 0.0 5.8 5 1 0 5 5 5 1 AAA domain AAA_33 PF13671.1 KII91092.1 - 1.9e-10 40.7 0.0 0.099 12.5 0.0 5.9 5 0 0 5 5 5 1 AAA domain AAA_28 PF13521.1 KII91092.1 - 8.3e-10 38.8 3.2 0.44 10.4 0.0 5.6 6 0 0 6 6 4 3 AAA domain MobB PF03205.9 KII91092.1 - 1e-09 38.1 0.4 1.7 8.3 0.0 5.4 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KII91092.1 - 2e-09 37.1 0.3 0.55 9.8 0.0 5.2 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KII91092.1 - 2.1e-09 37.7 1.9 0.044 14.0 0.0 5.5 6 0 0 6 6 4 2 ABC transporter RNA_helicase PF00910.17 KII91092.1 - 2.6e-08 33.9 0.1 3 8.0 0.0 5.6 5 0 0 5 5 5 0 RNA helicase AAA_29 PF13555.1 KII91092.1 - 5.3e-08 32.2 0.1 0.72 9.4 0.0 5.1 5 0 0 5 5 5 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KII91092.1 - 9.7e-08 31.6 0.4 0.28 10.5 0.0 4.9 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.16 KII91092.1 - 1.3e-07 31.0 0.1 6.4 5.8 0.0 6.4 7 0 0 7 7 6 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KII91092.1 - 1.6e-07 30.6 0.0 2.3 7.2 0.0 5.7 6 0 0 6 6 6 1 Zeta toxin NACHT PF05729.7 KII91092.1 - 3.7e-07 29.9 0.0 0.9 9.1 0.0 5.0 5 0 0 5 5 4 2 NACHT domain Miro PF08477.8 KII91092.1 - 1.2e-06 29.0 0.1 5.3 7.5 0.0 5.0 5 0 0 5 5 4 0 Miro-like protein DUF815 PF05673.8 KII91092.1 - 1.2e-05 24.3 0.0 1.4 7.7 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KII91092.1 - 1.3e-05 24.7 0.3 0.24 10.7 0.0 4.9 6 0 0 6 6 5 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KII91092.1 - 3.6e-05 23.5 0.0 2.2 7.9 0.0 5.1 5 0 0 5 5 5 1 Archaeal ATPase PduV-EutP PF10662.4 KII91092.1 - 4.9e-05 22.8 0.1 0.46 9.9 0.0 4.4 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KII91092.1 - 0.0001 22.7 0.0 5.9 7.1 0.0 4.3 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.17 KII91092.1 - 0.00018 21.0 0.0 6.9 6.0 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 KII91092.1 - 0.00019 21.2 1.2 5.1 6.7 0.1 5.5 7 1 1 8 8 4 0 NTPase RuvB_N PF05496.7 KII91092.1 - 0.00048 19.2 1.9 3 6.8 0.0 4.6 5 0 0 5 5 4 0 Holliday junction DNA helicase ruvB N-terminus Dynein_heavy PF03028.10 KII91092.1 - 0.0012 17.0 0.0 0.12 10.3 0.0 3.3 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor DEAD PF00270.24 KII91092.1 - 0.0016 17.9 0.1 3.7 7.0 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase ResIII PF04851.10 KII91092.1 - 0.0029 17.4 0.0 4.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KII91092.1 - 0.0047 16.4 0.1 0.38 10.2 0.0 3.9 6 0 0 6 6 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KII91092.1 - 0.0047 16.5 0.0 10 5.6 0.0 4.2 5 0 0 5 5 4 0 AAA domain cobW PF02492.14 KII91092.1 - 0.0053 16.2 2.5 9 5.6 0.0 5.2 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.8 KII91092.1 - 0.0053 15.5 0.1 5.7 5.5 0.0 3.6 4 0 0 4 4 3 0 TIP49 C-terminus DUF258 PF03193.11 KII91092.1 - 0.0056 15.8 2.2 4 6.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KII91092.1 - 0.012 15.1 0.4 28 4.2 0.0 3.9 5 0 0 5 5 3 0 AAA domain CbiA PF01656.18 KII91092.1 - 0.017 14.5 0.4 1.6 8.0 0.1 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.5 KII91092.1 - 0.022 13.9 0.1 74 2.4 0.0 4.7 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KII91092.1 - 0.024 14.6 0.4 13 5.8 0.0 4.2 5 0 0 5 5 4 0 50S ribosome-binding GTPase AAA_6 PF12774.2 KII91092.1 - 0.029 13.8 0.0 51 3.2 0.0 5.0 6 1 0 6 6 6 0 Hydrolytic ATP binding site of dynein motor region D1 IPT PF01745.11 KII91092.1 - 0.032 13.4 0.1 11 5.1 0.0 3.5 4 0 0 4 4 3 0 Isopentenyl transferase KTI12 PF08433.5 KII91092.1 - 0.057 12.6 0.6 72 2.4 0.0 4.7 6 0 0 6 6 5 0 Chromatin associated protein KTI12 AAA_7 PF12775.2 KII91092.1 - 0.075 12.0 0.0 1.2 8.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 PhoH PF02562.11 KII91092.1 - 0.076 12.2 0.3 9.6 5.3 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein Bac_DnaA PF00308.13 KII91092.1 - 0.082 12.5 0.0 19 4.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial dnaA protein KaiC PF06745.8 KII91092.1 - 0.11 11.5 0.8 22 4.0 0.0 3.2 3 0 0 3 3 3 0 KaiC KAP_NTPase PF07693.9 KII91092.1 - 0.15 10.9 0.0 49 2.7 0.0 3.2 3 0 0 3 3 3 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 KII91092.1 - 0.16 11.4 0.6 32 3.9 0.0 4.4 6 0 0 6 6 4 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 KII91092.1 - 0.16 10.5 0.3 34 2.9 0.0 3.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Gtr1_RagA PF04670.7 KII91092.1 - 0.21 10.7 2.0 1 8.4 0.0 2.8 4 0 0 4 4 2 0 Gtr1/RagA G protein conserved region AAA_26 PF13500.1 KII91092.1 - 0.33 10.5 0.4 26 4.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.16 KII91092.1 - 0.34 10.1 1.0 25 4.0 0.0 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KII91092.1 - 0.83 8.5 0.2 1e+02 1.6 0.0 3.3 3 0 0 3 3 3 0 PIF1-like helicase DAP3 PF10236.4 KII91092.1 - 1.2 7.9 0.9 50 2.6 0.0 3.4 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 KII91092.1 - 2.3 7.0 0.1 17 4.2 0.0 2.2 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 KII91092.1 - 4.6 6.7 4.0 30 4.0 0.1 3.7 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein LRR_6 PF13516.1 KII91093.1 - 3.8e-13 48.0 4.5 1.5 9.1 0.0 7.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.2 KII91093.1 - 1.5e-07 30.8 3.6 0.047 13.3 1.3 4.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII91093.1 - 5.3e-07 28.7 1.5 7.7 6.9 0.0 5.7 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 KII91093.1 - 2.3e-05 24.0 3.2 0.67 9.7 0.2 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 KII91093.1 - 0.21 11.8 7.8 60 4.5 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat SAC3_GANP PF03399.11 KII91094.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Phosphodiest PF01663.17 KII91095.1 - 2e-72 244.5 1.2 2.6e-72 244.1 0.8 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase OppC_N PF12911.2 KII91095.1 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C DUF500 PF04366.7 KII91096.1 - 8.7e-45 151.2 0.0 1.5e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Sec7 PF01369.15 KII91096.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Sec7 domain Nup160 PF11715.3 KII91097.1 - 0.0086 14.2 0.0 0.014 13.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 KII91097.1 - 0.057 13.3 8.1 0.39 10.6 0.0 4.0 3 1 0 3 3 3 0 WD domain, G-beta repeat BIR PF00653.16 KII91107.1 - 9.1e-32 109.2 2.3 2.9e-16 59.6 0.5 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 KII91107.1 - 4.8e-05 23.1 0.7 0.054 13.2 0.0 2.6 3 0 0 3 3 3 2 C3HC zinc finger-like zf-BED PF02892.10 KII91107.1 - 0.0015 18.2 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 BED zinc finger WAPL PF07814.8 KII91108.1 - 6.3e-05 21.8 0.0 0.00031 19.5 0.0 2.0 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Lactamase_B_2 PF12706.2 KII91109.1 - 1.2e-28 100.0 0.2 3e-28 98.7 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KII91109.1 - 1.5e-09 37.1 0.0 9.8e-09 34.5 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KII91109.1 - 3.2e-05 23.6 0.0 0.00032 20.4 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Kelch_6 PF13964.1 KII91112.1 - 0.11 12.7 0.1 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 Kelch motif DUF3433 PF11915.3 KII91113.1 - 3.7e-19 68.6 3.3 3.7e-19 68.6 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) GMC_oxred_N PF00732.14 KII91114.1 - 1.2e-57 195.3 0.0 2.3e-57 194.4 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII91114.1 - 2.6e-32 112.0 0.0 4.1e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KII91114.1 - 0.0014 17.5 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KII91114.1 - 0.002 18.1 0.1 0.0066 16.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII91114.1 - 0.004 16.1 0.3 0.022 13.6 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII91114.1 - 0.0043 15.9 0.1 0.0069 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KII91114.1 - 0.13 12.3 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII91114.1 - 0.25 9.7 0.1 0.45 8.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pmp3 PF01679.12 KII91116.1 - 2.6e-19 68.6 7.6 3.1e-19 68.3 5.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ECF-ribofla_trS PF07155.7 KII91116.1 - 0.046 13.4 0.5 0.058 13.1 0.4 1.2 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component MutS_V PF00488.16 KII91117.1 - 5.4e-97 323.8 0.0 8.5e-97 323.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KII91117.1 - 2.8e-36 125.2 3.3 3.9e-36 124.7 1.5 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 KII91117.1 - 5.6e-17 62.0 0.1 1.4e-15 57.5 0.0 2.8 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KII91117.1 - 1.3e-16 60.4 1.1 1.3e-16 60.4 0.7 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 KII91117.1 - 3.5e-09 36.6 0.0 1.1e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.1 KII91117.1 - 5.9 7.1 7.2 3.3 7.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain zf-MYND PF01753.13 KII91118.1 - 4.5e-07 29.6 12.0 1.2e-06 28.2 8.3 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KII91118.1 - 0.019 14.2 9.7 0.074 12.3 4.9 2.9 2 1 0 2 2 2 0 Life-span regulatory factor ATPase-cat_bd PF12156.3 KII91118.1 - 0.18 12.3 7.0 0.59 10.6 4.8 1.9 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase DZR PF12773.2 KII91118.1 - 1.1 9.1 8.6 3.3 7.6 6.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon Nol1_Nop2_Fmu PF01189.12 KII91119.1 - 2e-27 96.3 0.0 4.8e-18 65.5 0.0 3.2 3 0 0 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 KII91119.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.20 KII91120.1 - 2.7e-17 62.7 0.0 3.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91120.1 - 2e-11 43.4 0.0 2.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII91120.1 - 0.057 12.7 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Tannase PF07519.6 KII91121.1 - 5e-91 305.7 0.0 7.8e-87 291.9 0.0 3.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase La PF05383.12 KII91122.1 - 1.5e-15 56.7 0.0 2.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 La domain GRP PF07172.6 KII91122.1 - 1.4 9.4 11.0 4.4 7.8 7.6 1.9 1 0 0 1 1 1 0 Glycine rich protein family IBR PF01485.16 KII91124.1 - 3.8e-16 58.7 30.9 4.8e-10 39.1 5.0 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 KII91124.1 - 4.3e-05 23.4 6.7 4.3e-05 23.4 4.6 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII91124.1 - 5.8e-05 22.6 6.1 5.8e-05 22.6 4.2 4.0 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII91124.1 - 0.00041 19.9 5.9 0.00041 19.9 4.1 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII91124.1 - 0.003 17.3 6.7 0.003 17.3 4.6 3.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII91124.1 - 0.0072 16.1 8.3 0.0072 16.1 5.7 3.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KII91124.1 - 0.017 14.8 6.9 0.017 14.8 4.8 3.5 3 1 1 4 4 4 0 zinc-RING finger domain Eapp_C PF10238.4 KII91124.1 - 7.7 6.4 19.0 0.24 11.3 1.1 3.4 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF2611 PF11022.3 KII91126.1 - 1.4e-16 60.3 2.9 9.2e-16 57.6 2.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) G-alpha PF00503.15 KII91129.1 - 4.6e-109 364.6 0.0 5.6e-109 364.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII91129.1 - 3.7e-10 39.3 0.0 1.1e-06 27.9 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 KII91129.1 - 0.0023 17.4 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KII91129.1 - 0.019 14.1 0.0 0.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 KII91129.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Glyco_hydro_16 PF00722.16 KII91131.1 - 2.4e-07 30.2 0.0 4.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Arrestin_C PF02752.17 KII91132.1 - 0.03 14.4 0.0 2.5 8.2 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KII91132.1 - 0.038 13.8 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain AdoHcyase PF05221.12 KII91133.1 - 3.5e-137 455.6 0.0 4e-137 455.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KII91133.1 - 7.9e-83 276.1 0.5 1.2e-82 275.6 0.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KII91133.1 - 5.3e-09 35.4 0.1 1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KII91133.1 - 6.3e-05 22.3 0.2 0.0001 21.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KII91133.1 - 0.00087 19.2 0.1 0.0023 17.9 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KII91133.1 - 0.0022 17.6 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 KII91133.1 - 0.0037 17.5 0.2 0.01 16.0 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 KII91133.1 - 0.054 13.3 0.1 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mitochondr_Som1 PF11093.3 KII91134.1 - 2.7e-08 33.4 0.1 3.5e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 MFS_1 PF07690.11 KII91137.1 - 3.5e-30 104.9 34.1 3.1e-29 101.8 23.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 KII91137.1 - 0.061 12.6 2.1 0.37 10.0 1.5 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF21 WXG100 PF06013.7 KII91138.1 - 0.36 10.8 3.2 3.3 7.7 0.3 2.1 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF1556 PF07590.6 KII91139.1 - 0.0068 16.6 1.6 0.011 15.9 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1556) DUF566 PF04484.7 KII91140.1 - 1.2 8.5 5.0 2.2 7.7 3.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) BCIP PF13862.1 KII91142.1 - 1.3e-45 155.3 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein AdoMet_MTase PF07757.8 KII91143.1 - 3.6e-32 110.8 0.0 3.3e-31 107.6 0.0 2.1 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KII91143.1 - 0.00036 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KII91143.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII91143.1 - 0.012 16.1 0.1 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KII91143.1 - 0.045 13.3 0.2 0.077 12.5 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KII91143.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 KII91143.1 - 0.18 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KII91143.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Mito_carr PF00153.22 KII91144.1 - 9e-58 191.9 0.7 8.9e-22 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 KII91145.1 - 4.2e-59 200.2 0.0 4.8e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nab2 PF11517.3 KII91145.1 - 0.094 12.8 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.17 KII91146.1 - 3.5e-70 236.8 0.0 4.2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YrhK PF14145.1 KII91149.1 - 5.2 6.8 8.6 0.26 10.9 0.7 2.4 2 0 0 2 2 2 0 YrhK-like protein DUF4407 PF14362.1 KII91151.1 - 6.6 5.6 6.4 7.3 5.4 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.1 KII91154.1 - 7.5e-06 25.5 4.7 1.2e-05 24.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KII91154.1 - 3.8e-05 23.5 0.0 6.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KII91154.1 - 5e-05 22.8 5.5 7.9e-05 22.2 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII91154.1 - 5e-05 22.9 5.6 7.9e-05 22.2 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain RRM_1 PF00076.17 KII91154.1 - 0.0016 17.9 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 KII91154.1 - 0.039 13.7 5.7 0.085 12.6 4.0 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KII91154.1 - 0.082 12.9 7.1 0.15 12.0 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.7 KII91154.1 - 1.8 8.1 6.1 3.8 7.0 4.3 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Apolipoprotein PF01442.13 KII91155.1 - 3.2e-09 36.5 12.0 4.1e-09 36.2 8.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain OmpH PF03938.9 KII91155.1 - 7.1e-05 22.7 12.1 0.0001 22.2 8.4 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF883 PF05957.8 KII91155.1 - 0.00057 20.2 14.1 0.11 12.9 6.0 2.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) DUF3584 PF12128.3 KII91155.1 - 0.00058 17.3 12.8 0.0007 17.0 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prominin PF05478.6 KII91155.1 - 0.0016 16.1 3.2 0.0019 15.8 2.2 1.0 1 0 0 1 1 1 1 Prominin Exonuc_VII_L PF02601.10 KII91155.1 - 0.005 16.0 4.9 0.0062 15.7 3.4 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit SGT1 PF07093.6 KII91155.1 - 0.0072 14.7 9.6 0.0088 14.4 6.7 1.0 1 0 0 1 1 1 1 SGT1 protein Baculo_PEP_C PF04513.7 KII91155.1 - 0.012 15.3 6.9 0.33 10.7 1.9 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.3 KII91155.1 - 0.013 14.5 7.4 0.019 14.0 5.2 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein eIF-3c_N PF05470.7 KII91155.1 - 0.019 13.0 8.0 0.025 12.6 5.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4455 PF14643.1 KII91155.1 - 0.019 13.5 15.3 0.025 13.2 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) ApoLp-III PF07464.6 KII91155.1 - 0.02 14.8 12.7 0.038 14.0 8.8 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 KII91155.1 - 0.024 14.7 8.2 0.2 11.7 4.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF885 PF05960.6 KII91155.1 - 0.026 13.6 7.8 0.034 13.3 5.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF342 PF03961.8 KII91155.1 - 0.027 12.9 6.2 0.036 12.4 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mitofilin PF09731.4 KII91155.1 - 0.029 13.0 15.8 0.033 12.8 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein COG2 PF06148.6 KII91155.1 - 0.031 14.1 11.7 2 8.2 3.4 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PHTB1_C PF14728.1 KII91155.1 - 0.034 12.9 1.1 0.036 12.8 0.8 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus YtxH PF12732.2 KII91155.1 - 0.038 14.3 13.2 0.26 11.6 9.0 2.3 1 1 0 1 1 1 0 YtxH-like protein UPF0449 PF15136.1 KII91155.1 - 0.046 13.9 0.1 0.046 13.9 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF3376 PF11856.3 KII91155.1 - 0.049 13.0 8.3 0.056 12.8 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Ribosomal_L22 PF00237.14 KII91155.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e FUSC PF04632.7 KII91155.1 - 0.086 11.2 4.6 0.092 11.1 3.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.1 KII91155.1 - 0.09 11.2 12.7 0.053 11.9 6.1 1.6 1 1 1 2 2 2 0 AAA domain THP2 PF09432.5 KII91155.1 - 0.1 12.4 5.0 0.18 11.6 3.0 1.8 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF4407 PF14362.1 KII91155.1 - 0.13 11.2 9.9 0.17 10.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 KII91155.1 - 0.16 12.2 7.8 28 5.0 5.4 3.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mre11_DNA_bind PF04152.9 KII91155.1 - 0.17 11.7 10.0 0.67 9.7 2.8 2.3 1 1 1 2 2 2 0 Mre11 DNA-binding presumed domain Mod_r PF07200.8 KII91155.1 - 0.18 11.7 15.7 0.78 9.6 10.9 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ENT PF03735.9 KII91155.1 - 0.2 11.3 6.9 0.99 9.1 1.2 2.6 1 1 1 2 2 2 0 ENT domain DUF3394 PF11874.3 KII91155.1 - 0.21 11.1 1.3 0.25 10.8 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) WXG100 PF06013.7 KII91155.1 - 0.23 11.4 5.9 5.8 6.9 0.1 3.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG APG6 PF04111.7 KII91155.1 - 0.25 10.3 12.9 0.34 9.9 8.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1002 PF06207.6 KII91155.1 - 0.26 10.5 6.6 0.26 10.5 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) ApoO PF09769.4 KII91155.1 - 0.26 10.9 1.0 0.38 10.4 0.7 1.3 1 0 0 1 1 1 0 Apolipoprotein O ALMT PF11744.3 KII91155.1 - 0.28 9.7 1.5 0.33 9.5 1.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Borrelia_P83 PF05262.6 KII91155.1 - 0.3 9.3 9.6 0.34 9.1 6.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein tRNA-synt_1c PF00749.16 KII91155.1 - 0.3 9.7 4.9 0.36 9.4 3.4 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Mnd1 PF03962.10 KII91155.1 - 0.3 10.7 13.3 0.46 10.1 9.2 1.4 1 0 0 1 1 1 0 Mnd1 family AAA_32 PF13654.1 KII91155.1 - 0.33 9.5 11.6 0.45 9.1 8.0 1.3 1 1 0 1 1 1 0 AAA domain Anti-adapt_IraP PF10796.4 KII91155.1 - 0.33 11.3 7.5 5.8 7.3 4.2 3.1 1 1 2 3 3 3 0 Sigma-S stabilisation anti-adaptor protein AAA_11 PF13086.1 KII91155.1 - 0.46 10.0 3.1 0.55 9.7 2.1 1.1 1 0 0 1 1 1 0 AAA domain Phe_tRNA-synt_N PF02912.13 KII91155.1 - 0.47 10.2 12.3 5.1 6.8 0.4 3.1 1 1 2 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain HAUS-augmin3 PF14932.1 KII91155.1 - 0.48 9.5 10.9 0.66 9.1 7.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Herpes_UL25 PF01499.11 KII91155.1 - 0.48 8.6 8.1 0.56 8.4 5.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family TMF_DNA_bd PF12329.3 KII91155.1 - 0.51 10.1 23.9 2.7 7.8 0.2 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YfcL PF08891.6 KII91155.1 - 0.54 10.2 12.6 2 8.4 2.7 2.9 1 1 3 4 4 4 0 YfcL protein DIT1_PvcA PF05141.7 KII91155.1 - 0.55 9.5 4.9 0.88 8.8 3.4 1.4 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Baculo_p24 PF05073.7 KII91155.1 - 0.7 9.4 3.6 1.1 8.7 2.5 1.5 1 1 0 1 1 1 0 Baculovirus P24 capsid protein SBP_bac_7 PF03480.8 KII91155.1 - 0.74 8.8 7.3 1.4 8.0 2.9 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF3708 PF12501.3 KII91155.1 - 0.75 9.6 2.8 1.1 9.1 1.9 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF2361 PF10153.4 KII91155.1 - 1.1 9.5 10.9 8.5 6.6 7.6 2.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF1664 PF07889.7 KII91155.1 - 1.2 8.9 11.8 9.7 6.0 3.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Histidinol_dh PF00815.15 KII91155.1 - 1.2 7.6 6.5 2.1 6.9 4.4 1.5 1 1 0 1 1 1 0 Histidinol dehydrogenase HK97-gp10_like PF04883.7 KII91155.1 - 1.3 9.9 5.0 17 6.4 3.5 2.5 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF2229 PF09989.4 KII91155.1 - 1.4 8.3 6.8 2.7 7.4 4.8 1.5 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) BTV_NS2 PF04514.7 KII91155.1 - 1.6 7.5 10.4 1.9 7.3 7.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Atg14 PF10186.4 KII91155.1 - 1.6 7.6 13.6 3.8 6.3 9.5 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRF PF01765.14 KII91155.1 - 1.7 8.1 18.3 0.28 10.6 8.0 2.0 1 1 1 2 2 2 0 Ribosome recycling factor Erp_C PF06780.6 KII91155.1 - 1.8 8.4 13.8 5.4 6.8 9.3 2.0 1 1 0 1 1 1 0 Erp protein C-terminus AAA_16 PF13191.1 KII91155.1 - 1.8 8.5 7.2 11 5.8 5.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 KII91155.1 - 1.8 8.3 7.2 3.6 7.3 4.7 1.5 1 1 1 2 2 2 0 Domain of unknown function DUF87 ATP-synt_B PF00430.13 KII91155.1 - 1.9 8.3 19.5 0.79 9.5 10.6 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) HAD_2 PF13419.1 KII91155.1 - 2 8.6 5.0 11 6.2 3.4 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3135 PF11333.3 KII91155.1 - 2.1 8.5 6.4 8.5 6.6 0.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3135) V_ATPase_I PF01496.14 KII91155.1 - 2.2 6.0 9.2 2.7 5.7 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 KII91155.1 - 2.2 6.4 11.9 2.5 6.2 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 KII91155.1 - 2.3 7.7 14.6 4 6.9 10.1 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3416 PF11896.3 KII91155.1 - 2.3 8.1 8.7 1.7 8.5 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) DUF848 PF05852.6 KII91155.1 - 2.4 8.0 19.6 0.77 9.5 8.2 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Spore_III_AB PF09548.5 KII91155.1 - 2.5 7.8 6.5 6 6.5 4.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NAD_binding_5 PF07994.7 KII91155.1 - 2.6 7.4 4.2 3.6 7.0 2.9 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase vATP-synt_E PF01991.13 KII91155.1 - 2.6 7.2 18.9 0.82 8.9 6.2 2.2 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Acyl-CoA_dh_C PF12806.2 KII91155.1 - 3.3 7.5 5.7 1.3 8.8 0.9 2.3 1 1 3 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like DUF4071 PF13281.1 KII91155.1 - 3.3 6.4 11.5 3.1 6.5 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) Med4 PF10018.4 KII91155.1 - 3.6 6.9 14.7 1.5e+02 1.6 3.2 3.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Nuc-transf PF10127.4 KII91155.1 - 3.7 6.8 8.2 4.8 6.4 5.3 1.5 1 1 0 1 1 1 0 Predicted nucleotidyltransferase IncA PF04156.9 KII91155.1 - 3.9 7.0 21.1 8.6 5.9 14.6 1.4 1 1 0 1 1 1 0 IncA protein HisKA_3 PF07730.8 KII91155.1 - 4.7 7.6 12.8 18 5.7 1.8 3.2 1 1 1 2 2 2 0 Histidine kinase HSCB_C PF07743.8 KII91155.1 - 6 7.4 23.1 6.9 7.2 7.5 3.0 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.4 KII91155.1 - 7.5 6.7 10.6 8 6.7 4.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.6 KII91155.1 - 7.7 6.4 7.4 88 3.0 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HAUS6_N PF14661.1 KII91155.1 - 8.5 5.6 13.5 74 2.5 9.3 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SNF2_N PF00176.18 KII91157.1 - 2.6e-71 239.8 1.4 3.6e-71 239.4 1.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 KII91157.1 - 4.4e-11 42.2 4.3 8.1e-11 41.4 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII91157.1 - 1.7e-09 37.3 8.3 3.8e-09 36.2 5.7 1.7 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 KII91157.1 - 4.3e-09 36.1 0.0 1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KII91157.1 - 5.2e-09 35.9 7.4 1.2e-08 34.8 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII91157.1 - 1.1e-08 34.6 7.0 2.3e-08 33.5 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII91157.1 - 3.2e-08 33.1 1.6 4.5e-08 32.6 0.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KII91157.1 - 1.2e-07 31.4 5.4 6e-07 29.2 4.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KII91157.1 - 2.4e-07 30.3 6.5 4.9e-07 29.3 4.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 KII91157.1 - 5.6e-05 23.0 1.0 8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-Nse PF11789.3 KII91157.1 - 0.0088 15.5 4.8 0.021 14.3 3.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Corona_S2 PF01601.11 KII91157.1 - 0.21 9.6 0.2 6.4 4.7 0.1 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein NOA36 PF06524.7 KII91157.1 - 0.3 10.3 5.9 0.59 9.3 4.1 1.4 1 0 0 1 1 1 0 NOA36 protein zf-RING_4 PF14570.1 KII91157.1 - 0.51 9.9 5.2 1.7 8.2 3.6 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRF PF01765.14 KII91158.1 - 9.8e-28 96.6 0.0 1.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Ribosome recycling factor p450 PF00067.17 KII91159.1 - 2.7e-66 224.0 0.0 3.2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KII91163.1 - 8.5e-24 84.3 0.8 1.2e-23 83.8 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII91163.1 - 9.4e-16 58.3 0.2 1.1e-15 58.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII91163.1 - 5.2e-08 32.7 0.4 7.9e-08 32.1 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII91163.1 - 1.1e-05 25.4 0.2 1.5e-05 25.0 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KII91163.1 - 8.7e-05 21.7 0.0 0.018 14.1 0.0 2.7 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KII91163.1 - 0.0016 17.3 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain PAE PF03283.8 KII91163.1 - 0.03 12.9 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase TrkA_N PF02254.13 KII91163.1 - 0.061 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain G-alpha PF00503.15 KII91164.1 - 4.7e-130 433.7 0.0 5.8e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII91164.1 - 9e-11 41.3 0.1 4.4e-06 26.0 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 KII91164.1 - 0.007 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KII91164.1 - 0.033 14.3 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KII91164.1 - 0.04 13.3 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RPT PF13446.1 KII91165.1 - 0.044 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein Nop14 PF04147.7 KII91165.1 - 3.1 5.6 6.1 3.8 5.3 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cyt-b5 PF00173.23 KII91166.1 - 1.1e-13 50.7 0.0 2.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KII91166.1 - 1.1e-12 47.9 24.6 1.1e-12 47.9 17.0 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF2034 PF10356.4 KII91167.1 - 3.7e-29 101.2 0.0 3.1e-27 94.9 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KII91167.1 - 1.5e-07 31.2 0.0 3.3e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease ABC_membrane_2 PF06472.10 KII91168.1 - 2.2e-82 276.3 0.0 3.3e-82 275.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KII91168.1 - 6e-15 55.7 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.1 KII91168.1 - 0.0038 17.2 0.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 KII91168.1 - 0.034 13.9 0.1 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KII91168.1 - 0.036 13.4 0.3 0.2 11.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KII91168.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KII91168.1 - 0.072 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KII91168.1 - 0.076 13.1 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KII91168.1 - 0.13 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 KII91168.1 - 0.21 10.7 0.1 0.36 9.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 KII91168.1 - 0.22 10.7 0.0 1.5 7.9 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Apolipoprotein PF01442.13 KII91169.1 - 5e-07 29.4 13.9 2.3e-06 27.2 9.6 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 KII91169.1 - 0.0002 21.4 11.6 0.0023 17.9 1.2 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) OmpH PF03938.9 KII91169.1 - 0.00039 20.3 8.3 0.00055 19.9 1.6 2.2 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) DUF148 PF02520.12 KII91169.1 - 0.00066 19.4 3.9 0.00076 19.2 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function DUF148 DUF883 PF05957.8 KII91169.1 - 0.00067 20.0 17.2 0.0038 17.5 2.8 3.0 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 KII91169.1 - 0.0019 18.0 6.0 0.032 14.0 0.5 2.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 KII91169.1 - 0.0058 14.0 12.3 0.0065 13.8 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4407 PF14362.1 KII91169.1 - 0.007 15.3 12.8 0.013 14.4 8.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 KII91169.1 - 0.008 15.9 6.3 0.008 15.9 4.3 2.6 1 1 2 3 3 3 1 ATP synthase B/B' CF(0) Gp58 PF07902.6 KII91169.1 - 0.015 13.5 5.1 0.02 13.1 3.5 1.1 1 0 0 1 1 1 0 gp58-like protein IFT46_B_C PF12317.3 KII91169.1 - 0.018 14.4 0.5 0.018 14.4 0.4 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal FUSC PF04632.7 KII91169.1 - 0.018 13.5 5.8 0.024 13.0 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 KII91169.1 - 0.02 15.0 6.2 1.3 9.1 0.4 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 KII91169.1 - 0.031 14.0 1.7 0.031 14.0 1.2 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.6 KII91169.1 - 0.032 14.6 12.7 1.4 9.3 0.3 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal NYD-SP28 PF14772.1 KII91169.1 - 0.035 14.2 9.1 1.3 9.1 1.2 2.9 1 1 1 2 2 2 0 Sperm tail AAA_13 PF13166.1 KII91169.1 - 0.041 12.3 8.3 0.58 8.5 1.3 1.8 1 1 1 2 2 2 0 AAA domain Sec8_exocyst PF04048.9 KII91169.1 - 0.05 13.2 3.9 0.3 10.7 0.1 2.2 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain TBPIP PF07106.8 KII91169.1 - 0.053 13.0 9.0 0.44 10.0 2.8 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HalX PF08663.5 KII91169.1 - 0.056 13.4 1.3 0.056 13.4 0.9 4.4 1 1 3 4 4 3 0 HalX domain YwqJ-deaminase PF14431.1 KII91169.1 - 0.06 13.2 3.1 0.43 10.4 0.6 2.3 1 1 0 2 2 2 0 YwqJ-like deaminase Reo_sigmaC PF04582.7 KII91169.1 - 0.068 12.3 6.0 1.5 7.9 0.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 KII91169.1 - 0.072 12.0 7.7 0.094 11.6 4.7 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 KII91169.1 - 0.075 13.0 0.4 0.075 13.0 0.3 2.2 1 1 1 2 2 2 0 YlqD protein Fez1 PF06818.10 KII91169.1 - 0.093 12.7 11.6 0.16 12.0 8.0 1.4 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.7 KII91169.1 - 0.093 12.4 9.3 5.1 6.8 6.5 2.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein MIS13 PF08202.6 KII91169.1 - 0.12 11.3 5.6 0.17 10.9 3.9 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Prominin PF05478.6 KII91169.1 - 0.15 9.5 5.0 0.24 8.8 3.5 1.3 1 1 0 1 1 1 0 Prominin Filament PF00038.16 KII91169.1 - 0.15 11.4 16.4 0.18 11.2 3.9 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF2229 PF09989.4 KII91169.1 - 0.15 11.4 1.0 0.21 11.0 0.7 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) YtxH PF12732.2 KII91169.1 - 0.18 12.1 10.9 0.097 13.0 1.5 2.7 2 1 1 3 3 2 0 YtxH-like protein HCMV_UL139 PF12507.3 KII91169.1 - 0.19 11.8 2.8 3.8 7.6 2.0 2.4 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein WXG100 PF06013.7 KII91169.1 - 0.19 11.7 8.6 0.13 12.2 0.7 3.2 1 1 2 3 3 3 0 Proteins of 100 residues with WXG MDMPI_N PF11716.3 KII91169.1 - 0.2 12.0 6.2 0.13 12.7 2.1 2.1 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Trans_reg_C PF00486.23 KII91169.1 - 0.2 11.5 1.8 8.2 6.4 0.0 3.5 2 1 2 4 4 4 0 Transcriptional regulatory protein, C terminal DUF4200 PF13863.1 KII91169.1 - 0.22 11.4 10.1 0.086 12.7 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.14 KII91169.1 - 0.24 10.8 17.1 0.65 9.4 10.3 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family KLRAQ PF10205.4 KII91169.1 - 0.26 11.3 4.8 0.46 10.5 1.4 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF2580 PF10824.3 KII91169.1 - 0.27 11.6 8.5 0.14 12.5 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2580) HSP70 PF00012.15 KII91169.1 - 0.28 9.0 9.4 0.34 8.7 6.5 1.2 1 0 0 1 1 1 0 Hsp70 protein Mnd1 PF03962.10 KII91169.1 - 0.36 10.4 10.5 3.8 7.1 7.3 2.0 1 1 0 1 1 1 0 Mnd1 family Activator-TraM PF11657.3 KII91169.1 - 0.37 10.2 9.8 1.6 8.1 5.7 2.1 1 1 1 2 2 2 0 Transcriptional activator TraM PilJ PF13675.1 KII91169.1 - 0.45 10.8 7.1 3 8.2 2.6 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lectin_N PF03954.9 KII91169.1 - 0.5 9.7 4.2 16 4.8 2.9 2.2 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Rab5-bind PF09311.6 KII91169.1 - 0.53 10.1 15.0 4.5 7.1 10.2 1.9 1 1 1 2 2 2 0 Rabaptin-like protein GvpL_GvpF PF06386.6 KII91169.1 - 0.54 9.7 14.9 0.28 10.7 1.5 2.2 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF CENP-F_leu_zip PF10473.4 KII91169.1 - 0.72 9.7 16.0 4.4 7.1 7.6 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_lysis PF03245.8 KII91169.1 - 0.73 9.8 12.1 0.75 9.7 2.9 3.1 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein V_ATPase_I PF01496.14 KII91169.1 - 0.75 7.5 5.9 1 7.1 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC37_N PF03234.9 KII91169.1 - 0.82 9.9 9.3 1.1 9.6 6.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding IncA PF04156.9 KII91169.1 - 0.88 9.1 16.5 27 4.2 10.6 2.4 1 1 1 2 2 2 0 IncA protein Acyl-CoA_dh_C PF12806.2 KII91169.1 - 0.92 9.3 5.0 0.45 10.3 0.6 2.4 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Bacillus_HBL PF05791.6 KII91169.1 - 1.2 8.5 5.6 4.2 6.6 0.9 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.17 KII91169.1 - 1.3 9.0 13.0 1.5 8.8 5.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4618 PF15397.1 KII91169.1 - 1.4 8.1 9.5 4.4 6.5 6.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HrpB7 PF09486.5 KII91169.1 - 1.4 8.8 19.6 0.098 12.5 5.8 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.3 KII91169.1 - 1.5 8.6 15.2 67 3.3 0.3 4.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 KII91169.1 - 1.7 8.4 13.2 8.2 6.2 0.7 3.6 1 1 2 3 3 3 0 Prefoldin subunit TMF_TATA_bd PF12325.3 KII91169.1 - 1.9 8.2 14.1 0.17 11.6 4.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CorA PF01544.13 KII91169.1 - 2.3 7.1 10.7 1 8.3 1.3 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein FlxA PF14282.1 KII91169.1 - 2.8 7.9 6.1 8.3 6.4 2.4 2.3 1 1 1 2 2 2 0 FlxA-like protein Vps51 PF08700.6 KII91169.1 - 3.7 7.4 11.0 8.7 6.2 0.2 4.2 1 1 2 4 4 3 0 Vps51/Vps67 zf-C4H2 PF10146.4 KII91169.1 - 4 7.4 9.5 7 6.5 6.5 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Fzo_mitofusin PF04799.8 KII91169.1 - 4.3 6.6 6.3 7.6 5.8 0.2 2.8 1 1 2 3 3 3 0 fzo-like conserved region ISG65-75 PF11727.3 KII91169.1 - 4.5 6.2 12.0 3.5 6.5 4.9 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1640 PF07798.6 KII91169.1 - 4.6 7.2 10.2 36 4.3 7.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Phage_Mu_Gam PF07352.7 KII91169.1 - 4.8 6.6 11.9 1.1 8.8 1.1 3.1 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein PspA_IM30 PF04012.7 KII91169.1 - 5.9 6.1 17.9 6.6 6.0 10.9 2.0 1 1 1 2 2 2 0 PspA/IM30 family Bap31 PF05529.7 KII91169.1 - 7 6.0 11.2 1.5 8.2 0.6 2.8 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like TPD52 PF04201.10 KII91169.1 - 8.4 6.0 12.4 13 5.4 4.2 2.9 1 1 1 2 2 2 0 Tumour protein D52 family PEP-utilisers_N PF05524.8 KII91169.1 - 9 6.1 15.1 3.3 7.5 6.4 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Ax_dynein_light PF10211.4 KII91169.1 - 9.8 5.9 11.4 7.4 6.3 2.9 2.5 1 1 0 2 2 2 0 Axonemal dynein light chain HAUS6_N PF14661.1 KII91169.1 - 9.9 5.4 10.1 20 4.4 0.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RdRP PF05183.7 KII91170.1 - 1.1e-125 420.6 0.0 1.4e-125 420.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Glyco_hydro_28 PF00295.12 KII91171.1 - 8.3e-67 225.4 18.2 1e-66 225.1 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KII91171.1 - 1.6e-08 34.4 24.9 5e-08 32.8 17.1 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KII91171.1 - 3.9e-07 29.4 5.8 6.1e-07 28.8 4.0 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 KII91171.1 - 6.3e-06 25.5 6.8 1.3e-05 24.5 4.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) Chlam_PMP PF02415.12 KII91171.1 - 1.7 9.0 16.2 1.9 8.9 0.0 5.3 6 2 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat FA_desaturase PF00487.19 KII91173.1 - 4.9e-14 52.3 22.2 4.9e-14 52.3 15.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KII91173.1 - 7.5e-14 51.2 0.0 1.7e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Astro_capsid PF03115.9 KII91174.1 - 0.057 11.6 0.0 0.06 11.6 0.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor adh_short PF00106.20 KII91175.1 - 1.3e-21 77.2 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91175.1 - 7.7e-11 41.9 0.0 9.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII91175.1 - 2e-10 40.8 0.0 2.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 KII91175.1 - 0.003 16.9 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.1 KII91175.1 - 0.083 12.8 0.5 0.14 12.1 0.3 1.5 1 1 0 1 1 1 0 NADH(P)-binding CRISPR_Cas2 PF09827.4 KII91177.1 - 0.00019 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 CRISPR associated protein Cas2 DUF3806 PF12713.2 KII91178.1 - 0.012 15.0 0.4 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) DUF2034 PF10356.4 KII91179.1 - 4.1e-23 81.5 0.4 1.6e-21 76.3 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KII91179.1 - 9.4e-07 28.6 0.0 1.6e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Restriction endonuclease FA_desaturase PF00487.19 KII91180.1 - 1.9e-14 53.7 20.9 3.5e-14 52.8 14.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KII91180.1 - 8.2e-14 51.1 0.0 1.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2034 PF10356.4 KII91181.1 - 1.8e-28 98.9 0.0 1.5e-22 79.6 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KII91181.1 - 2e-07 30.8 0.0 6.8e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Restriction endonuclease DNA_mis_repair PF01119.14 KII91185.1 - 2.4e-27 94.7 0.0 4.3e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KII91185.1 - 1.5e-12 47.3 0.0 3.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KII91185.1 - 7.7e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.1 KII91186.1 - 2.7e-139 465.4 0.0 4e-139 464.8 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KII91186.1 - 1.1e-76 258.0 0.5 2.7e-76 256.7 0.1 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KII91186.1 - 1.1e-16 59.7 0.0 7.6e-09 33.7 0.0 3.2 3 0 0 3 3 3 3 Cell morphogenesis central region Cyclin_N PF00134.18 KII91187.1 - 3.2e-47 159.2 1.2 7.2e-47 158.1 0.8 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KII91187.1 - 6.1e-27 93.8 0.0 1.3e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3314 PF11771.3 KII91187.1 - 0.018 14.8 0.6 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) DSPc PF00782.15 KII91188.1 - 4e-05 23.2 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KII91188.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KII91188.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PC_rep PF01851.17 KII91189.1 - 1.3e-23 81.8 17.7 0.0003 20.8 0.1 8.9 8 0 0 8 8 8 7 Proteasome/cyclosome repeat CBS PF00571.23 KII91190.1 - 1.5e-06 27.9 0.0 0.00048 19.8 0.0 2.5 2 1 0 2 2 2 2 CBS domain HSP20 PF00011.16 KII91191.1 - 1.3e-13 50.6 0.0 7.4e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family tRNA-synt_1 PF00133.17 KII91192.1 - 1.2e-153 512.2 0.0 1.9e-153 511.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KII91192.1 - 1.6e-24 86.3 0.1 2.8e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KII91192.1 - 3.4e-22 78.6 0.1 2.3e-14 52.8 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 KII91192.1 - 3.6e-05 23.2 3.7 7.7e-05 22.2 2.5 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 KII91192.1 - 0.0021 17.2 0.0 1.2 8.1 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KII91192.1 - 0.065 12.0 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (R) ProRS-C_1 PF09180.6 KII91193.1 - 4.6e-24 84.1 0.3 1.1e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KII91193.1 - 8e-21 74.3 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KII91193.1 - 1.4e-15 57.0 0.0 3.6e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 KII91193.1 - 3.5e-13 49.4 0.0 7.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain FAM110_N PF14161.1 KII91193.1 - 0.057 13.6 0.2 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Centrosome-associated N terminus Suppressor_APC PF11414.3 KII91193.1 - 0.079 12.7 0.1 20 5.0 0.1 2.6 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein ProRS-C_1 PF09180.6 KII91194.1 - 4.6e-20 71.2 0.9 5.2e-20 71.1 0.6 1.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal Zn-ribbon_8 PF09723.5 KII91194.1 - 0.074 13.0 1.5 0.086 12.8 0.1 1.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KII91194.1 - 0.082 12.1 0.3 0.17 11.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DJ-1_PfpI PF01965.19 KII91196.1 - 1.7e-24 85.9 0.0 2.3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KII91196.1 - 2.4e-15 56.2 0.0 2.7e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KII91196.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CENP-F_leu_zip PF10473.4 KII91197.1 - 0.027 14.3 24.0 0.061 13.1 3.8 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KII91197.1 - 0.035 13.2 0.3 0.069 12.3 0.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FUSC PF04632.7 KII91197.1 - 0.057 11.8 6.2 0.088 11.2 4.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ParB PF08775.5 KII91197.1 - 0.062 13.6 1.6 0.11 12.8 0.3 1.9 1 1 0 1 1 1 0 ParB family APG6 PF04111.7 KII91197.1 - 0.24 10.4 15.3 0.16 11.0 1.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 KII91197.1 - 0.24 11.2 14.0 1.5 8.6 0.3 2.6 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KII91197.1 - 1.2 8.8 16.4 1.5 8.5 1.3 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KII91197.1 - 1.5 8.6 4.6 11 5.7 0.7 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) IFT57 PF10498.4 KII91197.1 - 1.7 7.2 6.3 2.8 6.5 4.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mnd1 PF03962.10 KII91197.1 - 3.2 7.3 14.8 9 5.9 3.6 2.3 1 1 1 2 2 2 0 Mnd1 family Fib_alpha PF08702.5 KII91197.1 - 3.9 7.5 5.3 4.8 7.2 1.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.8 KII91197.1 - 5.2 6.0 6.9 3.7 6.5 2.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF3584 PF12128.3 KII91197.1 - 9.4 3.4 17.7 26 1.9 12.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) adh_short PF00106.20 KII91198.1 - 3.9e-21 75.6 0.1 8e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII91198.1 - 8.6e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII91198.1 - 2.9e-09 36.8 0.1 4.9e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII91198.1 - 1.3e-07 31.8 1.2 8.6e-06 25.8 0.8 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII91198.1 - 0.00053 19.5 0.0 0.0012 18.3 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KII91198.1 - 0.015 15.3 0.8 0.11 12.5 0.2 2.4 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KII91198.1 - 0.018 14.2 0.3 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KII91198.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_18 PF00704.23 KII91199.1 - 2.4e-56 191.6 8.2 3.2e-56 191.2 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.19 KII91199.1 - 1.1e-14 54.2 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Cyt-b5 PF00173.23 KII91200.1 - 2.3e-22 78.5 0.0 4.6e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KII91200.1 - 1.4e-07 31.9 17.9 1.4e-07 31.9 12.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMP-binding PF00501.23 KII91201.1 - 3e-86 289.4 0.0 3.8e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII91201.1 - 7.7e-08 33.1 0.3 2.2e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.1 KII91202.1 - 5.6e-17 62.3 0.0 1.9e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII91202.1 - 1.5e-12 47.6 0.0 2.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KII91203.1 - 5.6e-16 59.1 0.0 1.3e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII91203.1 - 3.4e-12 46.5 0.0 5.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.22 KII91204.1 - 3.4e-56 186.9 0.4 2.4e-22 78.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein WND PF07861.6 KII91205.1 - 0.027 13.5 0.7 0.032 13.2 0.5 1.1 1 0 0 1 1 1 0 WisP family N-Terminal Region DUF1430 PF07242.6 KII91206.1 - 0.81 9.7 9.9 0.07 13.2 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1430) His_Phos_2 PF00328.17 KII91207.1 - 4.4e-28 98.6 0.0 7.2e-28 97.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.7 KII91208.1 - 4.6e-32 110.0 3.4 8.5e-32 109.1 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII91208.1 - 3.7e-16 58.8 0.0 5.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KII91208.1 - 0.00091 18.3 0.9 0.0013 17.8 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.1 KII91208.1 - 0.0018 19.1 0.0 0.0032 18.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2338 PF10100.4 KII91208.1 - 0.0054 15.1 0.0 0.0078 14.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2338) Saccharop_dh PF03435.13 KII91208.1 - 0.022 13.7 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KII91208.1 - 0.032 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KII91208.1 - 0.065 13.3 0.1 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3395 PF11875.3 KII91209.1 - 2.1e-07 30.6 0.0 2.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) Gti1_Pac2 PF09729.4 KII91210.1 - 6e-24 84.8 1.3 5.7e-21 75.1 0.0 2.7 2 1 0 3 3 3 2 Gti1/Pac2 family DUF605 PF04652.11 KII91210.1 - 1.1 8.6 9.4 1.2 8.4 6.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF155 PF02582.9 KII91211.1 - 1.4e-55 187.8 0.5 2.3e-55 187.1 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sec5 PF15469.1 KII91212.1 - 2.3e-60 203.4 0.8 2.7e-59 199.9 0.1 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 HhH-GPD PF00730.20 KII91213.1 - 1.6e-19 70.1 0.0 4.4e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KII91213.1 - 2.2e-09 36.7 0.0 1.7e-08 33.8 0.0 2.3 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.18 KII91213.1 - 0.0094 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KII91213.1 - 0.09 12.9 3.2 0.21 11.8 2.2 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III TauD PF02668.11 KII91214.1 - 8.4e-44 150.1 0.1 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KII91215.1 - 4.9e-21 74.8 16.0 4.9e-21 74.8 11.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M10 PF00413.19 KII91215.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Matrixin SURF4 PF02077.10 KII91216.1 - 1.1e-93 313.4 2.8 1.3e-93 313.2 1.9 1.0 1 0 0 1 1 1 1 SURF4 family Lactonase PF10282.4 KII91217.1 - 3.9e-21 75.5 0.0 6.3e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KII91217.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Corona_NS4 PF03905.8 KII91217.1 - 0.51 10.1 3.9 6.5 6.6 0.2 2.6 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 adh_short PF00106.20 KII91218.1 - 1.7e-10 41.0 0.9 5.4e-10 39.4 0.5 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII91218.1 - 1.3e-05 24.8 0.2 2.3e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII91218.1 - 0.0013 18.7 0.5 0.0028 17.6 0.4 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KII91218.1 - 0.0044 16.8 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII91218.1 - 0.16 11.4 0.1 0.29 10.5 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Treacle PF03546.9 KII91219.1 - 0.001 17.9 2.2 0.0017 17.2 1.5 1.2 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle Antistasin PF02822.9 KII91220.1 - 0.078 13.2 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Antistasin family AMP-binding PF00501.23 KII91221.1 - 7.9e-72 241.9 0.0 1.2e-71 241.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KII91221.1 - 1.6e-64 217.2 0.0 3.7e-64 216.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 KII91221.1 - 3.7e-14 52.7 0.0 1.4e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KII91221.1 - 1.2e-09 38.9 0.0 5.2e-09 36.9 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KII91221.1 - 4.5e-09 36.1 0.0 8.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII91221.1 - 0.0031 16.2 0.0 0.0087 14.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 KII91221.1 - 0.036 12.9 0.1 0.091 11.5 0.0 1.7 1 1 0 1 1 1 0 Condensation domain NUC153 PF08159.7 KII91223.1 - 1.3e-11 43.8 0.2 2.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 NUC153 domain DUF294 PF03445.8 KII91224.1 - 0.16 11.5 0.0 0.67 9.5 0.0 1.9 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 adh_short PF00106.20 KII91225.1 - 5e-19 68.8 0.2 8.8e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91225.1 - 6.1e-08 32.5 0.2 9.2e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII91225.1 - 8.3e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII91225.1 - 7e-06 26.1 0.6 1.3e-05 25.2 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII91225.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lactonase PF10282.4 KII91226.1 - 1.5e-27 96.5 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KII91226.1 - 0.0034 16.7 0.0 0.0091 15.3 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Abhydrolase_6 PF12697.2 KII91227.1 - 8.4e-33 114.1 3.1 9.9e-33 113.9 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII91227.1 - 8e-16 58.2 0.0 7e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII91227.1 - 1.1e-13 51.1 0.7 2.2e-13 50.1 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KII91227.1 - 1.7e-08 33.2 0.0 1.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KII91227.1 - 0.035 13.9 1.1 0.24 11.2 0.1 2.8 3 1 0 3 3 3 0 Putative lysophospholipase Ser_hydrolase PF06821.8 KII91227.1 - 0.096 12.2 0.3 0.3 10.6 0.1 1.9 1 1 1 2 2 2 0 Serine hydrolase Dioxygenase_C PF00775.16 KII91228.1 - 9.6e-46 155.3 0.0 1.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KII91228.1 - 4.4e-16 58.6 0.0 6.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KII91228.1 - 0.00024 21.0 0.0 0.00099 19.1 0.0 2.0 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain ADH_N PF08240.7 KII91229.1 - 1.2e-33 115.1 4.7 2.3e-33 114.2 3.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII91229.1 - 3.8e-15 55.5 0.0 6.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII91229.1 - 3.1e-05 24.8 0.0 0.00012 23.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KII91229.1 - 0.00031 19.9 0.5 0.00044 19.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 KII91229.1 - 0.011 15.8 0.1 0.027 14.5 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N_assoc PF13823.1 KII91229.1 - 0.045 13.4 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated MAF_flag10 PF01973.13 KII91229.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 NAD_binding_7 PF13241.1 KII91229.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding KH_1 PF00013.24 KII91230.1 - 7.6e-07 28.6 0.0 3.3e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KII91230.1 - 0.0061 16.1 0.3 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 KH domain DUF4160 PF13711.1 KII91230.1 - 0.1 12.4 0.3 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) K_channel_TID PF07941.6 KII91230.1 - 0.22 11.7 7.0 0.95 9.7 4.8 2.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Oxidored_FMN PF00724.15 KII91231.1 - 2.3e-77 260.2 0.0 2.8e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KII91231.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel HTH_15 PF12324.3 KII91232.1 - 0.46 10.1 4.4 9.6 5.9 0.9 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase C6 PF01681.12 KII91232.1 - 0.66 10.0 7.0 2.2 8.4 4.8 1.8 1 0 0 1 1 1 0 C6 domain Pkinase_Tyr PF07714.12 KII91233.1 - 5.8e-41 140.2 0.0 7.6e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII91233.1 - 4.2e-39 134.2 0.0 4.8e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII91233.1 - 0.00014 20.9 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII91233.1 - 0.0037 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KII91233.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII91233.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2413 PF10310.4 KII91234.1 - 0.52 9.0 10.9 0.75 8.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Peptidase_S64 PF08192.6 KII91234.1 - 1.8 6.8 6.0 2.5 6.3 4.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF2217 PF10265.4 KII91234.1 - 2.7 6.6 8.4 1.2 7.8 4.3 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) BCNT PF07572.7 KII91235.1 - 6.8e-19 67.5 0.0 1.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development Peptidase_M36 PF02128.10 KII91236.1 - 3.2e-117 391.5 10.4 4.6e-117 391.0 7.2 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KII91236.1 - 5.4e-05 22.5 0.1 0.00019 20.8 0.1 2.0 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif SRP19 PF01922.12 KII91237.1 - 1.4e-22 80.0 0.0 2.2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein DUF2360 PF10152.4 KII91237.1 - 0.2 11.9 6.9 0.41 10.9 1.5 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PAXIP1_C PF15364.1 KII91237.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.3 2 1 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Pex14_N PF04695.8 KII91237.1 - 0.86 9.6 4.7 6.2 6.8 0.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region JTB PF05439.7 KII91238.1 - 0.00019 21.1 0.3 0.0003 20.5 0.0 1.4 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) TALPID3 PF15324.1 KII91238.1 - 3.9 4.7 9.1 4.7 4.4 6.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target COesterase PF00135.23 KII91240.1 - 1.3e-38 133.0 0.0 1.1e-37 129.9 0.1 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII91240.1 - 0.0015 18.1 0.1 0.0047 16.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KII91240.1 - 0.003 16.5 0.0 0.0044 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF1720 PF08226.6 KII91240.1 - 0.12 12.4 1.3 0.2 11.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) SHMT PF00464.14 KII91241.1 - 1.8e-167 556.7 0.0 2.2e-167 556.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KII91241.1 - 0.0019 17.3 0.1 0.0062 15.7 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DUF2457 PF10446.4 KII91242.1 - 2.2 6.9 26.0 1.5 7.4 16.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 KII91242.1 - 6.7 5.0 16.4 5.1 5.4 10.4 1.5 1 1 0 1 1 1 0 Daxx Family DUF4336 PF14234.1 KII91243.1 - 2.6e-10 39.9 0.1 0.00013 21.2 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) 7tm_1 PF00001.16 KII91244.1 - 0.023 13.8 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Cu-oxidase PF00394.17 KII91245.1 - 3.8e-38 130.8 0.1 3.2e-36 124.6 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KII91245.1 - 9.4e-38 128.8 0.7 4.7e-34 116.8 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 KII91245.1 - 1.1e-33 115.4 0.3 1.8e-31 108.3 0.1 3.8 4 1 0 4 4 4 1 Multicopper oxidase FTR1 PF03239.9 KII91246.1 - 1.4e-64 217.9 7.9 1.6e-64 217.7 5.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Wzy_C PF04932.10 KII91246.1 - 8.2 6.1 12.3 0.15 11.7 0.5 2.9 2 2 1 3 3 3 0 O-Antigen ligase F-box-like PF12937.2 KII91247.1 - 4.5e-07 29.5 0.2 4.5e-07 29.5 0.1 3.0 3 1 1 4 4 4 1 F-box-like F-box-like PF12937.2 KII91249.1 - 4e-05 23.2 1.0 4e-05 23.2 0.7 2.5 1 1 1 2 2 2 1 F-box-like Spc7 PF08317.6 KII91249.1 - 0.13 10.9 0.1 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1241 PF06840.6 KII91249.1 - 0.13 11.5 0.1 0.29 10.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) zf-C2H2_4 PF13894.1 KII91251.1 - 0.0026 17.9 0.4 0.0069 16.6 0.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger Na_trans_assoc PF06512.8 KII91251.1 - 0.2 11.6 5.4 0.34 10.8 3.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.9 KII91251.1 - 0.74 7.7 5.6 1 7.3 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 KII91251.1 - 1.9 6.6 7.4 2.9 6.0 5.1 1.3 1 0 0 1 1 1 0 Transmembrane protein DAP3 PF10236.4 KII91252.1 - 1.5e-62 211.3 0.0 1.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 KII91252.1 - 0.00018 21.2 0.0 0.00055 19.6 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 KII91252.1 - 0.00046 19.7 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 KII91252.1 - 0.00051 20.0 0.1 0.0012 18.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 KII91252.1 - 0.002 16.9 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 KII91252.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KII91252.1 - 0.0057 16.0 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KII91252.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 KII91252.1 - 0.016 16.0 0.0 0.025 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KII91252.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KII91252.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KII91252.1 - 0.042 14.1 0.3 0.093 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII91252.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KII91252.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KII91252.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KII91252.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KII91252.1 - 0.11 12.6 0.1 0.82 9.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KII91252.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KII91252.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.20 KII91253.1 - 7.5e-69 231.7 0.0 8.7e-69 231.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91253.1 - 8.5e-31 106.9 0.0 1e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII91253.1 - 0.028 14.1 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KII91253.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like NUDIX PF00293.23 KII91254.1 - 5.1e-06 26.1 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain rve PF00665.21 KII91255.1 - 2.3e-05 24.4 0.0 4e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Integrase core domain CBFD_NFYB_HMF PF00808.18 KII91258.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3857 PF12969.2 KII91258.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) DAO PF01266.19 KII91260.1 - 7.5e-19 67.8 0.5 1.1e-18 67.2 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribosomal_S26e PF01283.14 KII91261.1 - 1.2e-50 170.4 7.6 1.5e-50 170.2 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 KII91261.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) BACON PF13004.2 KII91262.1 - 0.014 15.6 9.9 0.014 15.6 6.9 2.1 1 1 1 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Ribosomal_L28e PF01778.12 KII91262.1 - 0.49 10.8 2.9 0.66 10.3 1.2 1.8 1 1 0 1 1 1 0 Ribosomal L28e protein family DUF1034 PF06280.7 KII91262.1 - 4.5 7.7 8.3 1.2 9.5 3.3 2.0 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) zf-PARP PF00645.13 KII91263.1 - 2.3e-23 82.2 0.0 2.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Hc1 PF07432.8 KII91264.1 - 0.34 11.1 10.1 0.38 10.9 7.0 1.0 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Spt5_N PF11942.3 KII91264.1 - 0.34 11.5 6.6 0.38 11.3 4.6 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.1 KII91264.1 - 4.6 7.4 9.3 1.8 8.7 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) zf-C3HC4_3 PF13920.1 KII91265.1 - 2.2e-11 43.2 16.9 8.5e-10 38.1 4.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII91265.1 - 3.7e-10 39.4 22.9 3.3e-09 36.4 7.7 2.7 2 1 0 2 2 2 2 Ring finger domain zf-met PF12874.2 KII91265.1 - 7.7e-10 38.6 14.5 0.0011 19.1 0.1 4.7 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C3HC4_2 PF13923.1 KII91265.1 - 1.6e-08 34.4 23.3 7.2e-08 32.3 8.5 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.3 KII91265.1 - 3.8e-08 33.2 15.1 0.0021 18.1 0.1 4.3 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.1 KII91265.1 - 2.1e-06 27.3 10.1 2.1e-06 27.3 7.0 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII91265.1 - 3.8e-06 26.4 22.3 9.9e-06 25.1 7.3 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII91265.1 - 1.2e-05 25.3 3.5 1.2e-05 25.3 2.4 3.0 2 1 1 3 3 3 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KII91265.1 - 0.00051 19.8 4.2 0.00051 19.8 2.9 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KII91265.1 - 0.00055 19.5 3.2 0.00055 19.5 2.2 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C2H2_4 PF13894.1 KII91265.1 - 0.0011 19.1 0.5 0.1 12.9 0.1 6.0 4 2 1 5 5 4 2 C2H2-type zinc finger zf-C3HC4_4 PF15227.1 KII91265.1 - 0.0035 17.1 11.6 0.0035 17.1 8.0 3.2 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C2H2_2 PF12756.2 KII91265.1 - 0.0061 16.6 1.7 0.02 14.9 0.6 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-RING_6 PF14835.1 KII91265.1 - 0.019 14.7 7.5 0.019 14.7 5.2 2.6 2 1 1 3 3 3 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 KII91265.1 - 0.086 13.2 0.1 0.086 13.2 0.1 5.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KII91265.1 - 0.19 11.6 0.3 0.19 11.6 0.2 5.2 6 0 0 6 6 5 0 C2H2-type zinc finger Ecl1 PF12855.2 KII91265.1 - 0.2 10.9 8.2 0.74 9.1 0.0 3.8 4 0 0 4 4 4 0 Life-span regulatory factor FYVE PF01363.16 KII91265.1 - 3.2 7.7 18.1 6 6.8 2.2 3.5 2 2 0 2 2 2 0 FYVE zinc finger MFS_1 PF07690.11 KII91266.1 - 2.6e-19 69.1 16.7 3.4e-19 68.7 11.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HEAT_2 PF13646.1 KII91267.1 - 8e-07 29.2 3.8 0.038 14.2 0.0 5.9 5 2 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KII91267.1 - 1.4e-05 24.7 1.2 16 5.9 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KII91267.1 - 0.17 12.4 3.7 8.6 6.9 0.1 5.0 5 0 0 5 5 5 0 HEAT-like repeat Daxx PF03344.10 KII91267.1 - 0.38 9.1 15.5 0.59 8.5 10.7 1.2 1 0 0 1 1 1 0 Daxx Family ORC6 PF05460.8 KII91267.1 - 1.1 8.2 12.3 2 7.4 8.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NARP1 PF12569.3 KII91268.1 - 1.5e-177 591.5 2.2 5.7e-176 586.2 0.6 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KII91268.1 - 1.9e-13 49.8 15.0 0.00085 18.9 0.0 7.9 7 1 0 7 7 7 2 TPR repeat TPR_2 PF07719.12 KII91268.1 - 2.7e-13 48.7 16.8 0.0025 17.5 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII91268.1 - 3.1e-12 45.9 15.1 0.13 12.9 0.1 10.0 7 3 2 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII91268.1 - 2.3e-10 40.8 22.0 0.048 14.3 0.2 8.6 7 2 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII91268.1 - 2.6e-10 40.4 13.7 0.1 12.9 0.0 7.6 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KII91268.1 - 8e-09 34.7 6.1 0.0015 18.0 0.3 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII91268.1 - 1.2e-06 28.2 0.1 8.5 6.8 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII91268.1 - 2.2e-06 27.4 20.7 0.59 10.0 0.1 7.8 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KII91268.1 - 1.7e-05 24.2 3.4 0.2 11.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII91268.1 - 0.0026 18.1 14.3 1.5 9.4 0.2 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII91268.1 - 0.008 15.9 6.4 0.16 11.8 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII91268.1 - 0.015 15.1 9.2 4.3 7.2 0.0 5.7 5 2 2 7 7 7 0 Tetratricopeptide repeat MIT PF04212.13 KII91268.1 - 0.045 13.6 0.0 0.045 13.6 0.0 2.8 2 0 0 2 2 1 0 MIT (microtubule interacting and transport) domain Wzy_C PF04932.10 KII91269.1 - 0.082 12.6 0.2 0.082 12.6 0.2 2.6 3 0 0 3 3 3 0 O-Antigen ligase Sulfate_tra_GLY PF13792.1 KII91269.1 - 0.24 11.0 4.2 0.28 10.8 0.9 2.6 3 0 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif HLH PF00010.21 KII91270.1 - 2.2e-12 46.4 0.0 5.7e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.7 KII91270.1 - 0.2 9.5 6.2 0.32 8.8 4.3 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 KII91270.1 - 0.21 11.1 3.2 0.53 9.8 2.2 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region AT_hook PF02178.14 KII91270.1 - 0.31 10.8 10.1 0.37 10.6 5.2 2.6 2 0 0 2 2 2 0 AT hook motif CDC45 PF02724.9 KII91270.1 - 1.5 6.7 2.7 2.3 6.1 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein FA_desaturase PF00487.19 KII91271.1 - 2.5e-26 92.6 12.3 3.9e-26 92.0 8.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KII91271.1 - 4.3e-18 64.2 0.2 7.1e-18 63.5 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Acetyltransf_3 PF13302.1 KII91272.1 - 9.2e-11 42.0 0.2 1.9e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII91272.1 - 1.5e-05 24.9 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KII91272.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII91272.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 KII91273.1 - 8.7e-05 22.5 1.2 0.00019 21.4 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF4336 PF14234.1 KII91274.1 - 5e-11 42.3 0.0 4.4e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Hira PF07569.6 KII91275.1 - 3.9e-47 160.2 0.0 8.6e-47 159.1 0.0 1.6 1 1 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KII91275.1 - 6.5e-43 143.1 20.4 2.5e-09 36.6 0.3 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 KII91275.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 HIRA B motif MFS_1 PF07690.11 KII91276.1 - 6.3e-19 67.8 16.5 8.7e-19 67.4 11.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2910 PF11139.3 KII91276.1 - 0.00094 18.3 0.0 0.0019 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2910) MFS_1 PF07690.11 KII91277.1 - 1.1e-20 73.6 11.9 1.6e-20 73.1 8.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Prenyltrans PF00432.16 KII91278.1 - 0.093 12.3 0.7 0.18 11.3 0.5 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Ribosomal_L44 PF00935.14 KII91279.1 - 7.5e-36 121.9 11.5 1.1e-35 121.4 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 HMG-CoA_red PF00368.13 KII91280.1 - 2.9e-158 526.4 5.5 3.8e-158 526.0 3.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KII91280.1 - 1.2e-14 54.0 0.1 2.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KII91280.1 - 0.017 13.0 0.0 0.026 12.4 0.0 1.2 1 0 0 1 1 1 0 Patched family DUF647 PF04884.9 KII91281.1 - 9.1e-70 234.6 1.5 1.3e-69 234.2 1.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis F-box-like PF12937.2 KII91282.1 - 9.4e-06 25.2 1.2 3.6e-05 23.3 0.2 2.6 2 0 0 2 2 2 1 F-box-like S1-P1_nuclease PF02265.11 KII91283.1 - 1.1e-45 156.2 0.0 5.6e-42 144.1 0.0 2.8 3 0 0 3 3 3 2 S1/P1 Nuclease Methyltransf_16 PF10294.4 KII91284.1 - 4.9e-09 35.8 0.0 9.7e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 KII91284.1 - 0.0022 17.7 0.0 0.011 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII91284.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KII91284.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KII91284.1 - 0.12 11.9 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KII91284.1 - 0.14 12.6 0.0 2.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Metallophos PF00149.23 KII91285.1 - 7.9e-43 146.1 0.6 1.1e-42 145.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pol_alpha_B_N PF08418.5 KII91285.1 - 3.3 7.1 4.8 5.9 6.3 3.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal UNC-50 PF05216.8 KII91286.1 - 1.4e-84 282.9 11.0 1.6e-84 282.7 7.6 1.0 1 0 0 1 1 1 1 UNC-50 family WW PF00397.21 KII91287.1 - 1e-08 34.8 1.2 2e-08 33.9 0.8 1.5 1 0 0 1 1 1 1 WW domain FMN_bind_2 PF04299.7 KII91287.1 - 0.14 11.5 0.1 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain TFIIF_alpha PF05793.7 KII91287.1 - 0.21 9.8 6.5 0.26 9.5 4.0 1.6 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4646 PF15496.1 KII91289.1 - 2e-20 73.0 0.7 3.7e-20 72.1 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) SR-25 PF10500.4 KII91289.1 - 0.00061 19.3 12.5 0.00085 18.8 8.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4337 PF14235.1 KII91289.1 - 0.047 13.5 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PBP_sp32 PF07222.7 KII91289.1 - 1.3 8.1 3.6 2 7.5 2.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Corona_nucleoca PF00937.13 KII91289.1 - 4.1 6.2 13.9 5.5 5.8 9.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDC45 PF02724.9 KII91289.1 - 7.7 4.4 9.8 9.8 4.0 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sin3_corepress PF08295.7 KII91290.1 - 1.1e-37 127.8 0.1 2.7e-37 126.5 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KII91290.1 - 6.9e-30 102.4 4.9 5e-14 51.6 0.0 3.8 4 0 0 4 4 4 3 Paired amphipathic helix repeat Aldedh PF00171.17 KII91291.1 - 2.1e-123 412.0 5.6 2.6e-123 411.7 3.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII91291.1 - 4.7e-07 28.8 0.1 1.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KII91291.1 - 0.0088 15.2 0.0 0.043 13.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF4646 PF15496.1 KII91292.1 - 1.5e-18 66.9 0.0 2.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 KII91292.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family GLTSCR1 PF15249.1 KII91292.1 - 0.092 12.8 0.7 0.19 11.8 0.5 1.5 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region Fucose_iso_C PF02952.12 KII91292.1 - 8.6 5.8 8.7 91 2.5 6.0 2.2 1 1 0 1 1 1 0 L-fucose isomerase, C-terminal domain Mg_trans_NIPA PF05653.9 KII91293.1 - 4.1e-100 334.6 11.1 5.1e-100 334.2 7.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KII91293.1 - 2.7e-06 27.5 0.3 2.7e-06 27.5 0.2 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KII91293.1 - 0.01 15.8 3.7 0.01 15.8 2.6 2.7 2 2 0 2 2 2 0 EamA-like transporter family RseC_MucC PF04246.7 KII91293.1 - 6.1 6.4 8.3 10 5.7 0.0 3.1 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC AAA_12 PF13087.1 KII91294.1 - 4.8e-44 150.1 0.0 7.4e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII91294.1 - 5.6e-33 114.4 0.0 1.5e-15 57.4 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KII91294.1 - 1.2e-13 51.1 0.0 5.9e-13 48.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII91294.1 - 7.1e-12 44.9 0.0 1.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 KII91294.1 - 8.1e-06 25.3 0.0 0.0081 15.4 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 KII91294.1 - 8.7e-05 22.1 0.0 0.0039 16.6 0.0 2.3 1 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 KII91294.1 - 0.00026 21.1 0.0 0.00086 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KII91294.1 - 0.0019 17.4 0.0 0.031 13.5 0.0 2.4 1 1 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 KII91294.1 - 0.0048 16.7 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KII91294.1 - 0.018 15.0 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 KII91294.1 - 0.026 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 KII91294.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.9 KII91294.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C PF13361.1 KII91294.1 - 0.075 12.4 0.0 7.7 5.8 0.0 2.2 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KII91294.1 - 0.091 12.9 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KII91294.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 KII91294.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KII91294.1 - 0.14 12.0 0.0 4 7.3 0.0 2.7 2 1 0 2 2 1 0 AAA domain AAA PF00004.24 KII91295.1 - 1e-43 148.6 0.0 1.9e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KII91295.1 - 3.6e-08 33.5 0.0 9.1e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KII91295.1 - 7.7e-07 28.9 0.0 4.2e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KII91295.1 - 5.4e-06 26.5 0.1 0.00031 20.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KII91295.1 - 5.9e-06 26.3 0.4 1.7e-05 24.8 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 KII91295.1 - 7.4e-05 23.5 0.1 0.00017 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII91295.1 - 7.9e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KII91295.1 - 0.00011 21.8 0.2 0.0003 20.4 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 KII91295.1 - 0.00032 20.1 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KII91295.1 - 0.00085 18.1 0.0 0.0015 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KII91295.1 - 0.0013 18.5 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KII91295.1 - 0.0018 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KII91295.1 - 0.002 17.2 0.0 0.0047 16.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF2072 PF09845.4 KII91295.1 - 0.0026 17.6 0.1 0.0058 16.5 0.1 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_28 PF13521.1 KII91295.1 - 0.0033 17.4 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KII91295.1 - 0.0036 16.8 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KII91295.1 - 0.0054 17.0 0.1 0.03 14.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain PhoH PF02562.11 KII91295.1 - 0.0058 15.8 0.0 0.073 12.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KII91295.1 - 0.0073 15.4 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KII91295.1 - 0.015 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 KII91295.1 - 0.017 14.5 0.0 0.087 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KII91295.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KII91295.1 - 0.024 13.5 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KII91295.1 - 0.028 13.8 0.1 0.077 12.3 0.0 1.7 1 1 1 2 2 2 0 AAA domain DivIC PF04977.10 KII91295.1 - 0.033 13.6 0.1 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Septum formation initiator RNA_helicase PF00910.17 KII91295.1 - 0.034 14.3 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KII91295.1 - 0.035 13.7 0.0 0.57 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KII91295.1 - 0.043 13.8 0.0 0.16 12.0 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KII91295.1 - 0.05 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KII91295.1 - 0.087 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_12 PF13087.1 KII91296.1 - 2.8e-44 150.8 0.0 4.3e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII91296.1 - 2.6e-35 122.1 0.0 9e-17 61.4 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KII91296.1 - 3.5e-13 49.5 0.0 2.8e-12 46.6 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KII91296.1 - 3.7e-12 45.8 0.1 1.7e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 KII91296.1 - 0.00014 21.3 0.0 0.0042 16.4 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 KII91296.1 - 0.0023 17.9 0.0 0.017 15.0 0.0 2.4 3 1 0 3 3 2 1 AAA ATPase domain PhoH PF02562.11 KII91296.1 - 0.0028 16.9 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 KII91296.1 - 0.01 16.0 0.0 0.04 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KII91296.1 - 0.014 14.9 0.0 22 4.4 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KII91296.1 - 0.03 13.7 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.24 KII91296.1 - 0.049 13.8 0.2 0.37 10.9 0.1 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 KII91296.1 - 0.052 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 KII91296.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 KII91296.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KII91296.1 - 0.074 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KII91296.1 - 0.11 11.9 0.0 0.67 9.3 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain UvrD_C PF13361.1 KII91296.1 - 0.32 10.3 0.2 15 4.9 0.0 2.2 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Syndecan PF01034.15 KII91297.1 - 0.16 11.6 0.1 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain NAD_binding_10 PF13460.1 KII91298.1 - 1.1e-05 25.5 0.0 4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF3562 PF12085.3 KII91300.1 - 0.12 12.2 1.1 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Pribosyltran PF00156.22 KII91301.1 - 1.3e-13 50.8 0.4 2.6e-13 49.8 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain G-alpha PF00503.15 KII91302.1 - 1.1e-145 485.2 0.0 1.3e-145 484.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII91302.1 - 5.4e-08 32.2 0.1 0.00014 21.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KII91302.1 - 0.0015 18.0 0.0 0.005 16.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KII91302.1 - 0.011 14.9 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KII91302.1 - 0.071 13.2 0.0 0.42 10.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain DAP3 PF10236.4 KII91302.1 - 0.11 11.4 0.2 0.34 9.8 0.3 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 KII91302.1 - 0.12 12.6 0.0 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AA_kinase PF00696.23 KII91305.1 - 6.6e-38 130.6 0.0 1.7e-36 125.9 0.0 2.2 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KII91305.1 - 2.1e-12 46.2 0.3 3.9e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KII91305.1 - 5.7e-09 35.3 1.9 1.5e-06 27.6 0.2 2.9 3 0 0 3 3 3 2 ACT domain DUF3318 PF11780.3 KII91305.1 - 0.037 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Sec1 PF00995.18 KII91306.1 - 2.5e-119 399.4 0.0 2.9e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peripla_BP_4 PF13407.1 KII91306.1 - 0.052 12.9 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain ChAPs PF09295.5 KII91307.1 - 3e-147 490.5 0.0 1.1e-145 485.3 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 KII91307.1 - 6e-07 29.5 0.9 1.7 8.8 0.2 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KII91307.1 - 4.7e-06 26.8 0.8 0.002 18.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 KII91307.1 - 8.8e-05 21.6 1.7 0.56 9.2 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII91307.1 - 0.00012 21.9 0.9 0.83 9.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII91307.1 - 0.00019 21.0 0.6 0.046 13.3 0.0 3.6 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.1 KII91307.1 - 0.00064 20.1 1.0 1.5e+02 3.4 0.0 6.1 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KII91307.1 - 0.00087 18.9 0.1 4 7.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII91307.1 - 0.00094 18.9 0.1 17 5.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII91307.1 - 0.041 14.3 0.1 31 5.3 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat NARP1 PF12569.3 KII91307.1 - 0.18 10.5 0.1 1 8.0 0.0 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF2046 PF09755.4 KII91308.1 - 1.1e-11 44.1 5.8 1.5e-11 43.8 2.5 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) HSP20 PF00011.16 KII91310.1 - 2.1e-10 40.3 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DER1 PF04511.10 KII91311.1 - 5.5e-31 107.6 0.6 6.8e-31 107.3 0.4 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KII91311.1 - 0.0098 15.9 9.5 0.021 14.8 6.6 1.6 1 1 0 1 1 1 1 Rhomboid family DUF3482 PF11981.3 KII91311.1 - 9.6 5.3 6.5 14 4.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Ion_trans_2 PF07885.11 KII91312.1 - 1.4e-28 98.4 30.3 1.6e-17 63.0 6.5 3.0 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.21 KII91312.1 - 0.02 14.6 0.9 0.02 14.6 0.6 2.7 3 0 0 3 3 3 0 Ligand-gated ion channel Herpes_UL45 PF05473.7 KII91312.1 - 0.078 12.3 0.4 0.28 10.5 0.1 1.9 2 0 0 2 2 2 0 UL45 protein TauD PF02668.11 KII91313.1 - 2.1e-30 106.2 0.0 3.6e-30 105.5 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KII91313.1 - 0.0046 15.9 0.0 0.0083 15.0 0.0 1.3 1 0 0 1 1 1 1 CsiD DUF432 PF04254.8 KII91313.1 - 0.084 12.7 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF432) AAA_12 PF13087.1 KII91314.1 - 4.3e-44 150.3 0.0 1.1e-43 149.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KII91314.1 - 6.5e-33 114.2 0.0 6.6e-16 58.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KII91314.1 - 2e-12 47.1 0.0 6.7e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII91314.1 - 1.3e-11 44.0 0.0 3.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 KII91314.1 - 6.2e-06 25.7 0.0 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KII91314.1 - 0.0008 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII91314.1 - 0.0024 18.0 0.0 0.011 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KII91314.1 - 0.0024 17.1 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 KII91314.1 - 0.003 17.1 0.0 6.6 6.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF3505 PF12013.3 KII91314.1 - 0.024 14.8 0.3 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) DUF2075 PF09848.4 KII91314.1 - 0.052 12.5 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KII91314.1 - 0.056 13.6 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KII91314.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KII91314.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KII91314.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C PF13361.1 KII91314.1 - 0.22 10.9 0.0 5.4 6.3 0.0 2.3 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain PIGA PF08288.7 KII91315.1 - 6.5e-36 122.5 0.4 2.2e-35 120.8 0.3 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KII91315.1 - 1.7e-26 92.6 0.0 2.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KII91315.1 - 1.3e-12 47.7 0.4 3e-12 46.6 0.3 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KII91315.1 - 2.3e-12 47.2 0.0 5.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KII91315.1 - 8.6e-12 45.4 0.2 1.9e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KII91315.1 - 7.9e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Oxysterol_BP PF01237.13 KII91317.1 - 4.2e-51 173.5 0.0 4.3e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein CorA PF01544.13 KII91320.1 - 7.5e-09 35.0 2.0 1.5e-08 34.0 1.4 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Syntaxin PF00804.20 KII91320.1 - 0.076 13.1 0.7 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 Syntaxin zf-RING_5 PF14634.1 KII91321.1 - 1.5e-06 27.8 13.3 1.5e-06 27.8 9.2 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII91321.1 - 8.5e-06 25.6 14.0 8.5e-06 25.6 9.7 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII91321.1 - 2.8e-05 23.6 11.8 2.8e-05 23.6 8.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII91321.1 - 9.2e-05 22.0 13.1 9.2e-05 22.0 9.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 KII91321.1 - 0.00019 21.5 1.9 0.00019 21.5 1.3 4.4 5 0 0 5 5 4 2 Zinc finger, C2H2 type zf-RING_2 PF13639.1 KII91321.1 - 0.0002 21.1 13.5 0.0002 21.1 9.3 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 KII91321.1 - 0.00053 19.7 8.4 0.00053 19.7 5.8 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF1213 PF06740.7 KII91321.1 - 0.0039 17.2 0.3 0.0039 17.2 0.2 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF1213) zf-met PF12874.2 KII91321.1 - 0.0055 16.8 0.4 0.0055 16.8 0.3 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KII91321.1 - 0.0064 16.7 2.0 0.0064 16.7 1.4 4.4 4 1 0 4 4 3 1 C2H2-type zinc finger zf-RING_UBOX PF13445.1 KII91321.1 - 0.019 14.6 4.9 0.019 14.6 3.4 3.2 2 2 0 2 2 2 0 RING-type zinc-finger zf-C2H2_jaz PF12171.3 KII91321.1 - 0.32 11.1 10.0 0.54 10.4 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.9 KII91321.1 - 3.9 7.0 8.7 3.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif WD40 PF00400.27 KII91322.1 - 7.5e-36 120.7 14.2 5.1e-08 32.5 0.4 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat MFS_1 PF07690.11 KII91323.1 - 3.9e-51 173.8 21.8 5.5e-51 173.3 15.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KII91323.1 - 5e-06 24.8 2.3 9.2e-05 20.6 0.7 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.20 KII91324.1 - 8.3e-08 32.3 0.1 1.4e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase zf-MYND PF01753.13 KII91325.1 - 2.1e-09 37.0 16.6 2.1e-09 37.0 11.5 2.0 2 0 0 2 2 2 1 MYND finger NAD_binding_10 PF13460.1 KII91326.1 - 2.3e-14 53.8 0.0 2.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KII91326.1 - 0.031 14.5 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII91326.1 - 0.052 12.4 0.1 0.25 10.2 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Aminotran_1_2 PF00155.16 KII91327.1 - 1.5e-51 175.4 0.0 1.8e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 KII91328.1 - 4.5e-71 232.4 22.7 1.9e-14 52.8 1.2 7.8 7 1 1 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KII91328.1 - 5.5e-09 35.3 0.0 0.042 13.3 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 KII91328.1 - 4.9e-07 28.8 0.1 0.6 8.7 0.0 5.0 1 1 2 4 4 4 4 Nup133 N terminal like PHF5 PF03660.9 KII91329.1 - 5.6e-51 171.1 8.0 6.2e-51 170.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KII91329.1 - 0.27 11.0 14.7 0.047 13.5 4.6 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 KII91329.1 - 0.43 10.3 14.3 2.3 7.9 0.3 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KII91329.1 - 1.3 8.7 14.1 0.034 13.8 3.7 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 KII91329.1 - 6.6 4.2 6.4 7.2 4.1 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 KII91329.1 - 9.6 6.0 13.0 10 5.9 4.9 2.7 1 1 0 1 1 1 0 zinc-ribbons UCH PF00443.24 KII91330.1 - 3.2e-45 154.3 0.0 4.8e-45 153.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII91330.1 - 1.5e-12 47.5 0.0 2.5e-06 27.1 0.0 3.1 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase TSP9 PF11493.3 KII91330.1 - 4.5 7.8 6.0 0.44 11.1 0.3 2.3 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Bin3 PF06859.7 KII91331.1 - 1.4e-34 118.3 0.0 2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 KII91331.1 - 3.7e-15 56.4 0.0 6.9e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII91331.1 - 1.1e-14 54.5 0.0 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII91331.1 - 1.3e-09 37.8 0.0 3e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KII91331.1 - 5.1e-09 36.4 0.0 0.00046 20.6 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 KII91331.1 - 5.2e-08 33.2 0.0 0.0087 16.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KII91331.1 - 1.8e-06 27.9 0.1 4.3e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII91331.1 - 1.2e-05 24.4 0.0 0.001 18.1 0.0 2.6 2 1 1 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 KII91331.1 - 6.1e-05 23.3 0.0 0.00042 20.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII91331.1 - 0.0005 19.2 0.0 0.00095 18.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KII91331.1 - 0.00078 19.0 0.0 0.0033 16.9 0.0 1.9 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KII91331.1 - 0.0011 18.0 0.1 0.08 12.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KII91331.1 - 0.0021 17.4 0.0 0.0088 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KII91331.1 - 0.0026 16.9 0.0 0.078 12.0 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 KII91331.1 - 0.061 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.7 KII91331.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DEAD PF00270.24 KII91332.1 - 9.3e-39 132.6 0.1 2.5e-36 124.7 0.0 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KII91332.1 - 1.9e-18 66.0 0.1 3.5e-17 62.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CTP_synth_N PF06418.9 KII91333.1 - 2.2e-93 312.3 0.0 3e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KII91333.1 - 3.6e-49 166.8 0.0 5.6e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KII91333.1 - 4e-05 23.1 0.0 0.00015 21.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 CBFD_NFYB_HMF PF00808.18 KII91334.1 - 4.1e-15 55.5 0.9 7.9e-15 54.6 0.6 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KII91334.1 - 4.3e-07 29.9 0.7 7.4e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ABC_membrane PF00664.18 KII91335.1 - 3.2e-47 161.2 21.2 9e-29 100.7 5.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII91335.1 - 3e-40 137.6 0.1 2.2e-26 92.7 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII91335.1 - 1e-10 41.2 2.6 0.045 12.9 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KII91335.1 - 1.7e-08 34.1 0.2 0.0023 17.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KII91335.1 - 2.4e-08 34.3 0.5 0.35 10.7 0.1 4.0 2 2 0 3 3 3 3 AAA domain T2SE PF00437.15 KII91335.1 - 1.8e-06 27.0 0.1 0.00046 19.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 KII91335.1 - 5.2e-06 25.8 2.6 0.0089 15.5 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KII91335.1 - 6.9e-06 26.1 0.6 0.046 13.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KII91335.1 - 9.2e-06 26.1 0.9 0.00028 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KII91335.1 - 1.4e-05 24.7 0.2 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KII91335.1 - 0.00019 22.2 0.6 0.27 12.0 0.3 3.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KII91335.1 - 0.00022 20.9 0.7 0.48 10.1 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.10 KII91335.1 - 0.0011 17.7 0.0 0.0059 15.3 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_22 PF13401.1 KII91335.1 - 0.0011 19.0 0.8 0.4 10.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KII91335.1 - 0.0013 18.6 1.0 0.11 12.2 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KII91335.1 - 0.0015 18.8 0.0 0.43 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KII91335.1 - 0.0031 17.2 0.0 0.12 12.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KII91335.1 - 0.0042 16.5 0.2 3 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 KII91335.1 - 0.0072 16.8 0.0 2.7 8.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KII91335.1 - 0.01 15.7 0.4 0.62 10.0 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF258 PF03193.11 KII91335.1 - 0.017 14.3 0.1 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 KII91335.1 - 0.018 14.8 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KII91335.1 - 0.043 13.5 0.1 0.93 9.1 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 KII91335.1 - 0.044 13.2 0.1 14 5.1 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.7 KII91335.1 - 0.057 12.7 0.8 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.1 KII91335.1 - 0.066 12.7 0.3 2.6 7.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KII91335.1 - 0.067 12.7 0.5 9.8 5.6 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KII91335.1 - 0.072 12.5 0.1 15 4.9 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 KII91335.1 - 0.076 12.7 0.8 17 5.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KII91335.1 - 0.094 12.5 0.5 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 KII91335.1 - 0.096 12.5 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KII91335.1 - 0.12 12.3 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 KII91335.1 - 0.21 11.1 0.0 0.53 9.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 KII91335.1 - 0.23 11.6 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KII91335.1 - 0.23 11.0 1.6 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.4 KII91335.1 - 0.28 9.7 1.3 11 4.5 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 KII91335.1 - 0.37 10.4 2.7 2 8.0 0.1 2.7 3 0 0 3 3 2 0 NTPase cobW PF02492.14 KII91335.1 - 0.42 10.0 3.8 0.47 9.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 2-Hacid_dh_C PF02826.14 KII91336.1 - 3.2e-41 140.4 0.0 4.9e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII91336.1 - 8.9e-23 80.2 0.0 1.1e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KII91336.1 - 0.0028 18.0 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 KII91338.1 - 8.4e-75 251.4 1.7 1e-74 251.2 1.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KII91338.1 - 6.1e-47 158.4 0.0 2.3e-46 156.6 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Lipocalin_4 PF13648.1 KII91339.1 - 0.033 14.7 1.0 0.64 10.6 0.1 2.3 2 0 0 2 2 2 0 Lipocalin-like domain adh_short PF00106.20 KII91340.1 - 6.2e-22 78.2 1.2 1.6e-21 76.9 0.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII91340.1 - 2.5e-09 37.2 0.0 8.7e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII91340.1 - 9e-09 35.2 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII91340.1 - 0.0091 15.7 0.1 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-RING_2 PF13639.1 KII91341.1 - 9.6e-07 28.5 8.4 1.8e-06 27.6 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII91341.1 - 1.2e-05 25.2 3.8 2.8e-05 24.1 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KII91341.1 - 1.9e-05 24.5 5.3 3.9e-05 23.5 3.7 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KII91341.1 - 0.0047 16.7 2.2 0.0098 15.7 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KII91341.1 - 0.027 14.5 7.1 0.06 13.4 4.9 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 KII91341.1 - 0.038 13.6 9.8 0.069 12.8 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 KII91341.1 - 1 9.1 5.4 0.36 10.5 1.8 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 KII91341.1 - 2.4 8.2 9.6 4.9 7.2 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII91341.1 - 2.8 7.6 6.0 5.7 6.6 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII91341.1 - 9.8 5.8 6.9 20 4.8 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_M24 PF00557.19 KII91342.1 - 2.1e-43 148.3 0.0 3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KII91342.1 - 1.9e-23 83.3 0.0 9e-20 71.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain F-box-like PF12937.2 KII91343.1 - 0.063 13.0 0.1 0.063 13.0 0.1 2.4 3 0 0 3 3 3 0 F-box-like adh_short PF00106.20 KII91344.1 - 2.1e-31 109.1 3.5 2.7e-31 108.7 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII91344.1 - 1.1e-23 84.2 0.1 1.3e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII91344.1 - 1.2e-09 38.1 1.8 1.8e-09 37.5 1.2 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII91345.1 - 5.2e-09 36.2 0.0 7.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII91345.1 - 0.00017 21.5 0.6 0.00037 20.4 0.1 1.7 1 1 1 2 2 2 1 short chain dehydrogenase bZIP_1 PF00170.16 KII91346.1 - 3.3e-08 33.3 5.3 8.9e-08 31.9 3.7 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KII91346.1 - 1.2e-05 25.0 3.6 1.2e-05 25.0 2.5 2.6 2 1 1 3 3 3 2 Basic region leucine zipper DUF4140 PF13600.1 KII91346.1 - 1.2 9.5 4.8 0.33 11.4 0.8 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_Maf PF03131.12 KII91346.1 - 1.9 8.8 8.9 0.13 12.6 2.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF1183 PF06682.7 KII91346.1 - 2.1 7.8 5.6 5.9 6.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) PAP2 PF01569.16 KII91348.1 - 4.9e-18 65.0 5.9 6.7e-18 64.6 2.9 2.2 2 0 0 2 2 2 1 PAP2 superfamily DUF1614 PF07758.6 KII91348.1 - 0.0036 17.0 1.5 0.036 13.8 0.5 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1614) PRiA4_ORF3 PF07929.6 KII91349.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein p450 PF00067.17 KII91350.1 - 6.3e-68 229.3 0.0 7.2e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SQS_PSY PF00494.14 KII91350.1 - 0.0038 16.5 0.1 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase HLH PF00010.21 KII91351.1 - 2.2e-18 65.6 0.0 7.8e-18 63.9 0.0 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Tyrosinase PF00264.15 KII91355.1 - 2.2e-30 106.5 8.1 2.9e-30 106.0 5.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase IF4E PF01652.13 KII91357.1 - 8.2e-49 165.3 0.0 1.2e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ATP_bind_1 PF03029.12 KII91358.1 - 7.3e-74 248.2 0.0 8.7e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KII91358.1 - 0.071 12.9 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KII91358.1 - 0.28 11.9 3.1 1 10.1 1.8 2.3 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 KII91359.1 - 8.6e-17 60.3 8.3 0.00011 21.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 KII91359.1 - 1.3e-10 41.2 0.0 1.3e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 KII91359.1 - 0.042 13.3 0.3 6.1 6.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.24 KII91361.1 - 2.1e-16 59.8 0.0 5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII91361.1 - 3.4e-11 42.8 0.1 1.7e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 KII91361.1 - 4.4e-06 26.3 0.1 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 RQC domain DUF870 PF05912.6 KII91361.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Pox_Ag35 PF03286.9 KII91361.1 - 0.14 11.6 7.3 0.27 10.7 5.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 KII91361.1 - 0.37 10.2 3.1 0.57 9.5 2.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO GST_N_3 PF13417.1 KII91363.1 - 8.4e-12 45.1 0.1 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII91363.1 - 1.8e-08 34.1 0.5 3.9e-08 33.0 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KII91363.1 - 3.5e-08 33.3 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KII91363.1 - 0.00034 21.0 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KII91363.1 - 0.00045 20.1 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 KII91363.1 - 0.00048 20.0 0.1 0.001 19.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KII91363.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NTP_transf_5 PF14907.1 KII91364.1 - 0.002 17.4 0.1 0.0037 16.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised nucleotidyltransferase DUF2204 PF09970.4 KII91364.1 - 0.012 15.0 0.0 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) NTP_transf_2 PF01909.18 KII91364.1 - 0.068 13.5 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyltransferase domain CPSF_A PF03178.10 KII91367.1 - 8.1e-76 255.1 0.0 1.9e-75 253.9 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 KII91367.1 - 0.048 13.9 0.2 12 6.3 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain SET PF00856.23 KII91368.1 - 1.3e-12 48.3 0.0 7e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 SET domain Vg_Tdu PF07545.9 KII91369.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Vestigial/Tondu family CBFD_NFYB_HMF PF00808.18 KII91370.1 - 7.5e-27 93.1 0.3 1.4e-26 92.3 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KII91370.1 - 5.4e-06 26.4 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KII91370.1 - 0.0091 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PAN_3 PF08277.7 KII91370.1 - 0.061 12.9 0.1 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.8 KII91370.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 KII91370.1 - 0.16 12.2 0.1 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A LZ_Tnp_IS66 PF13007.2 KII91371.1 - 0.54 10.9 19.0 4.1 8.1 6.6 3.5 4 0 0 4 4 4 0 Transposase C of IS166 homeodomain DUF3886 PF13025.1 KII91371.1 - 1.6 8.7 11.9 4.7 7.2 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF605 PF04652.11 KII91371.1 - 2.8 7.2 19.2 3.7 6.8 13.3 1.1 1 0 0 1 1 1 0 Vta1 like Lyase_aromatic PF00221.14 KII91372.1 - 3e-144 481.0 5.9 6.1e-144 479.9 1.5 2.6 2 1 0 2 2 2 1 Aromatic amino acid lyase WD40 PF00400.27 KII91373.1 - 6.7e-06 25.7 1.0 0.0023 17.7 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat SET PF00856.23 KII91374.1 - 2.5e-16 60.4 0.7 3.8e-15 56.5 0.5 2.6 1 1 0 1 1 1 1 SET domain TCR PF03638.10 KII91374.1 - 9.8 6.1 45.4 0.2 11.5 9.3 3.3 3 0 0 3 3 3 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain APH PF01636.18 KII91376.1 - 2.6e-15 56.8 0.7 5.6e-15 55.7 0.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII91376.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SnoaL_3 PF13474.1 KII91376.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain LexA_DNA_bind PF01726.11 KII91378.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 LexA DNA binding domain RNA_lig_T4_1 PF09511.5 KII91379.1 - 4.6e-76 255.1 0.0 7.9e-76 254.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KII91379.1 - 3.3e-28 98.6 0.2 5.8e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 KII91379.1 - 2.1e-19 69.7 0.0 7.6e-19 67.9 0.0 1.9 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 KII91379.1 - 0.00092 20.0 0.0 0.0024 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KII91379.1 - 0.013 14.7 0.1 0.034 13.3 0.0 1.6 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 KII91379.1 - 0.052 13.4 0.3 0.29 11.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain Exo70 PF03081.10 KII91380.1 - 2.7e-40 138.3 0.0 4.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Snapin_Pallidin PF14712.1 KII91380.1 - 0.038 14.3 3.3 0.084 13.1 1.4 2.3 2 0 0 2 2 2 0 Snapin/Pallidin MTBP_N PF14918.1 KII91380.1 - 0.091 12.1 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding CTNNBL PF08216.6 KII91380.1 - 0.11 12.0 3.2 0.1 12.1 1.0 1.9 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear GCR PF02155.10 KII91380.1 - 0.17 10.6 0.5 0.28 9.8 0.4 1.2 1 0 0 1 1 1 0 Glucocorticoid receptor Sec63 PF02889.11 KII91381.1 - 4.4e-196 650.3 0.0 2e-104 349.2 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KII91381.1 - 1.3e-52 177.6 0.3 2.1e-28 98.9 0.1 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KII91381.1 - 1.9e-17 63.7 0.1 4.2e-10 39.7 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KII91381.1 - 1e-12 47.7 0.0 9.4e-09 35.0 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KII91381.1 - 3.2e-07 30.5 0.1 0.039 14.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 KII91381.1 - 0.0003 20.0 0.0 0.019 14.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 KII91381.1 - 0.0063 15.4 0.0 0.13 11.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KII91381.1 - 0.039 13.3 0.0 0.94 8.8 0.0 3.2 2 2 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 KII91381.1 - 0.82 9.9 8.4 1.9 8.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain UDG PF03167.14 KII91382.1 - 1.3e-15 57.2 0.0 1.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Herpes_LP PF03363.8 KII91383.1 - 0.00038 20.0 1.6 0.0006 19.4 0.5 1.8 1 1 1 2 2 2 1 Herpesvirus leader protein Mating_C PF12737.2 KII91383.1 - 0.88 8.3 11.0 1.1 8.0 7.6 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 F-box-like PF12937.2 KII91384.1 - 0.031 13.9 0.1 0.08 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like DEAD PF00270.24 KII91386.1 - 1.2e-41 142.0 0.1 3.1e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII91386.1 - 2.8e-17 62.3 0.0 6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KII91386.1 - 4.3e-06 25.7 0.0 7.8e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KII91386.1 - 2.9e-05 23.7 0.7 0.001 18.7 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KII91386.1 - 0.0068 16.2 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Kelch_4 PF13418.1 KII91387.1 - 1e-27 95.6 9.9 1.9e-06 27.5 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KII91387.1 - 1.5e-25 88.6 12.3 3.2e-07 30.3 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.1 KII91387.1 - 2.8e-22 78.3 0.0 2.8e-22 78.3 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 KII91387.1 - 1.6e-19 69.1 6.0 2e-05 24.5 0.0 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KII91387.1 - 3.8e-17 61.5 0.6 1.3e-05 24.6 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KII91387.1 - 1.2e-14 53.8 13.0 5.9e-05 22.9 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KII91387.1 - 3.3e-09 36.1 9.3 0.023 14.4 1.1 4.9 4 1 0 4 4 4 3 Kelch motif Atg14 PF10186.4 KII91388.1 - 4.1e-53 180.3 0.0 5.9e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Zwint PF15556.1 KII91388.1 - 0.0089 15.3 1.9 0.013 14.7 1.3 1.2 1 0 0 1 1 1 1 ZW10 interactor HlyD PF00529.15 KII91388.1 - 0.019 14.3 6.8 0.028 13.7 4.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 KII91388.1 - 0.019 14.0 0.6 0.04 12.9 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 HRDC PF00570.18 KII91388.1 - 0.038 13.7 0.7 0.077 12.7 0.5 1.5 1 0 0 1 1 1 0 HRDC domain GlnE PF03710.10 KII91388.1 - 0.046 12.9 1.1 0.077 12.2 0.7 1.3 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase EzrA PF06160.7 KII91388.1 - 0.05 11.7 0.3 0.062 11.4 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Hemerythrin PF01814.18 KII91388.1 - 0.057 13.5 0.3 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain 4HBT_3 PF13622.1 KII91388.1 - 0.15 11.7 4.5 0.51 10.0 0.8 2.2 2 0 0 2 2 2 0 Thioesterase-like superfamily zf-B_box PF00643.19 KII91388.1 - 1.1 9.1 4.5 2.1 8.3 3.1 1.4 1 0 0 1 1 1 0 B-box zinc finger F-box-like PF12937.2 KII91389.1 - 3.3e-05 23.5 0.1 9.8e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.7 KII91390.1 - 1.8e-10 40.5 0.3 2.4e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KII91390.1 - 2.2e-06 27.2 0.3 3.6e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated RVT_1 PF00078.22 KII91393.1 - 3.4e-08 33.1 0.0 3.6e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KII91394.1 - 4.3e-06 27.1 0.0 9.8e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 RNase H ADH_zinc_N PF00107.21 KII91395.1 - 1.7e-11 43.7 0.1 3.3e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII91395.1 - 4.4e-05 23.2 0.2 8.7e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HI0933_like PF03486.9 KII91395.1 - 0.00016 20.3 0.3 0.00059 18.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KII91395.1 - 0.0068 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KII91395.1 - 0.048 12.5 0.2 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_18 PF12847.2 KII91395.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KII91395.1 - 0.051 13.5 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KII91395.1 - 0.061 12.9 0.1 0.079 12.6 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KII91395.1 - 0.065 12.2 0.1 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KII91395.1 - 0.084 13.2 0.2 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KII91395.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KII91395.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KII91395.1 - 0.12 12.4 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L33 PF00471.15 KII91396.1 - 1.4e-08 34.8 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.3 KII91396.1 - 0.029 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal GCN5L1 PF06320.8 KII91397.1 - 0.077 12.8 0.3 0.088 12.6 0.2 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Prion_bPrPp PF11587.3 KII91397.1 - 0.13 11.9 0.3 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Robl_LC7 PF03259.12 KII91398.1 - 9.4e-07 28.3 0.0 9.5e-06 25.1 0.0 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain zf-MYND PF01753.13 KII91399.1 - 1.8e-08 34.1 13.3 1.8e-08 34.1 9.2 2.2 3 0 0 3 3 3 1 MYND finger Metallophos_2 PF12850.2 KII91402.1 - 4.6e-16 59.0 0.0 5.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KII91402.1 - 0.0013 18.1 0.0 0.0039 16.6 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 KII91403.1 - 3.6e-16 58.8 53.4 5.1e-15 55.0 34.8 3.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KII91403.1 - 9.2e-07 27.4 34.8 9.7e-06 24.0 24.1 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 KII91403.1 - 0.11 12.5 0.3 0.11 12.5 0.2 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 CorA PF01544.13 KII91403.1 - 7.3 5.5 9.1 1.8 7.5 3.7 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TraH PF06122.6 KII91405.1 - 0.18 10.6 0.4 0.32 9.7 0.0 1.5 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein BTB PF00651.26 KII91406.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.5 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 KII91407.1 - 1.5e-05 24.9 0.2 2.4e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyoxal_oxid_N PF07250.6 KII91409.1 - 4.4e-38 130.7 1.4 3.2e-35 121.3 0.0 4.0 4 1 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KII91409.1 - 8.5e-23 80.3 0.3 2.6e-22 78.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF2510 PF10708.4 KII91409.1 - 0.84 9.1 3.6 2.7 7.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) Kelch_4 PF13418.1 KII91409.1 - 9.9 6.0 11.9 2.9 7.7 0.1 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain zf-MYND PF01753.13 KII91410.1 - 2.2e-09 36.9 15.0 4.7e-09 35.9 10.4 1.5 1 0 0 1 1 1 1 MYND finger Glyoxal_oxid_N PF07250.6 KII91411.1 - 1.6e-37 128.9 2.2 5.5e-35 120.5 0.1 4.0 4 1 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KII91411.1 - 2.2e-22 78.9 1.9 2.8e-22 78.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) DUF4243 PF14027.1 KII91412.1 - 7.1e-96 321.5 0.0 9.2e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DELLA PF12041.3 KII91412.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Chs3p PF12271.3 KII91413.1 - 1.8e-48 165.0 10.0 3.5e-48 164.0 6.9 1.4 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit RBM1CTR PF08081.6 KII91414.1 - 0.95 9.2 9.4 0.55 10.0 3.9 2.6 2 0 0 2 2 2 0 RBM1CTR (NUC064) family F-box-like PF12937.2 KII91415.1 - 4.6e-06 26.2 0.9 8.7e-06 25.3 0.6 1.5 1 1 0 1 1 1 1 F-box-like HMG_box PF00505.14 KII91416.1 - 2.6e-11 43.6 0.0 5.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII91416.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain Aldo_ket_red PF00248.16 KII91417.1 - 1.5e-69 233.9 0.0 1.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KII91418.1 - 4.3e-06 26.3 4.2 4.3e-06 26.3 2.9 3.0 3 0 0 3 3 3 1 F-box-like IncA PF04156.9 KII91418.1 - 0.0064 16.1 1.1 0.01 15.4 0.8 1.3 1 0 0 1 1 1 1 IncA protein LRR_8 PF13855.1 KII91418.1 - 0.099 12.4 0.4 27 4.6 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat GPP34 PF05719.6 KII91424.1 - 1.5e-58 198.2 0.1 1.9e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) G-alpha PF00503.15 KII91425.1 - 5.5e-124 413.8 0.1 6.6e-124 413.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII91425.1 - 3.4e-12 45.9 0.6 3.5e-08 32.8 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 KII91425.1 - 0.0046 16.4 0.0 0.0097 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KII91425.1 - 0.006 16.5 0.1 0.98 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KII91425.1 - 0.015 15.4 0.2 0.066 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KII91425.1 - 0.02 14.3 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KII91425.1 - 0.026 13.6 0.0 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ERCC4 PF02732.10 KII91425.1 - 0.03 14.0 0.1 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 ERCC4 domain ATP_bind_1 PF03029.12 KII91425.1 - 0.034 13.7 0.2 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Myosin_head PF00063.16 KII91425.1 - 0.057 11.4 0.0 0.22 9.5 0.0 1.8 2 0 0 2 2 2 0 Myosin head (motor domain) AAA_16 PF13191.1 KII91425.1 - 0.092 12.7 2.5 0.45 10.4 1.8 2.2 1 1 0 1 1 1 0 AAA ATPase domain Acetyltransf_7 PF13508.1 KII91428.1 - 2e-10 40.6 0.0 3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII91428.1 - 3.8e-08 33.2 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII91428.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII91428.1 - 6.2e-05 22.6 0.0 9.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KII91428.1 - 0.0009 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 KII91428.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 WD40 PF00400.27 KII91429.1 - 1.9e-26 90.9 15.1 2.7e-08 33.3 0.0 7.1 6 1 1 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KII91429.1 - 0.00033 20.4 0.1 0.053 13.2 0.0 3.0 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.20 KII91431.1 - 3.6e-39 134.4 0.0 5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91431.1 - 1.3e-38 132.5 0.0 2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII91431.1 - 8.6e-07 28.1 0.0 1.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII91431.1 - 0.00051 19.8 0.1 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII91431.1 - 0.0083 15.2 0.2 0.022 13.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KII91431.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KII91431.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family 4HBT PF03061.17 KII91432.1 - 1.6e-12 47.4 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KII91432.1 - 4.1e-06 27.2 0.0 5.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KII91432.1 - 0.0018 17.2 0.5 0.0027 16.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase Proteasome PF00227.21 KII91433.1 - 1.8e-36 125.2 0.0 2.2e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sad1_UNC PF07738.8 KII91435.1 - 3.3e-20 72.2 0.0 4.4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal WD40 PF00400.27 KII91436.1 - 0.0075 16.1 0.0 0.09 12.6 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat MCM PF00493.18 KII91438.1 - 0.021 13.6 0.1 0.025 13.3 0.0 1.0 1 0 0 1 1 1 0 MCM2/3/5 family DUF4218 PF13960.1 KII91440.1 - 3.3e-05 23.3 0.1 6.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4194 PF13835.1 KII91440.1 - 0.052 12.9 0.0 0.31 10.4 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4194) G-alpha PF00503.15 KII91443.1 - 3.4e-112 374.9 0.3 4e-112 374.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII91443.1 - 1.4e-14 53.7 0.3 4e-10 39.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII91443.1 - 2.3e-05 23.6 0.1 0.06 12.4 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KII91443.1 - 0.015 15.7 0.1 10 6.6 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KII91443.1 - 0.021 14.3 0.1 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KII91443.1 - 0.024 14.0 0.1 5.2 6.4 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SNF2_N PF00176.18 KII91444.1 - 1.8e-72 243.6 0.0 2.4e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII91444.1 - 5.7e-16 58.1 0.0 1.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII91444.1 - 1.9e-05 24.2 0.0 4.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII91444.1 - 0.00017 21.4 0.0 0.00053 19.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Crust_neurohorm PF01147.12 KII91444.1 - 0.085 12.1 0.2 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family DUF3584 PF12128.3 KII91445.1 - 0.00095 16.6 7.1 0.0012 16.2 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HalX PF08663.5 KII91445.1 - 0.028 14.4 1.8 0.46 10.5 0.0 3.4 3 1 1 4 4 4 0 HalX domain Spc7 PF08317.6 KII91445.1 - 0.29 9.7 6.2 0.5 8.9 4.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.4 KII91445.1 - 6.1 6.8 7.4 18 5.2 0.1 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 JmjC PF02373.17 KII91448.1 - 0.0017 18.5 0.1 0.0061 16.7 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase CMD PF02627.15 KII91449.1 - 2.1e-11 43.4 0.1 3.5e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Glyco_hydr_30_2 PF14587.1 KII91451.1 - 2.3e-17 63.0 2.6 4.3e-17 62.1 1.8 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 ICMT PF04140.9 KII91452.1 - 8.4e-15 54.7 0.3 2.9e-14 53.0 0.1 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII91452.1 - 1.3e-12 47.7 4.4 4.4e-12 46.0 0.8 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KII91452.1 - 0.0083 14.7 0.1 0.012 14.1 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KII91452.1 - 0.021 14.1 0.2 0.021 14.1 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DSPc PF00782.15 KII91453.1 - 1.7e-24 85.9 0.0 2.3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII91453.1 - 0.0031 16.8 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CTP_transf_1 PF01148.15 KII91454.1 - 2.9e-12 46.7 6.7 7.4e-09 35.6 2.6 2.3 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_S8 PF00410.14 KII91455.1 - 2.9e-26 91.8 0.1 4e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 KII91456.1 - 1.3e-57 192.8 0.1 1.5e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cu_amine_oxid PF01179.15 KII91457.1 - 2.7e-156 520.4 0.0 3.4e-156 520.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KII91457.1 - 5.7e-16 58.4 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KII91457.1 - 1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Hist_deacetyl PF00850.14 KII91458.1 - 1.7e-77 260.7 0.5 2.3e-77 260.3 0.4 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SSF PF00474.12 KII91459.1 - 1.1e-14 53.9 30.3 1.1e-14 53.9 21.0 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family CAS_CSE1 PF03378.10 KII91460.1 - 1.6e-111 372.7 0.0 2.3e-111 372.1 0.0 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KII91460.1 - 3e-100 335.3 0.0 4.7e-100 334.7 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KII91460.1 - 1.6e-11 43.9 0.0 1.1e-10 41.2 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KII91460.1 - 0.0017 18.3 0.2 0.078 12.8 0.0 3.4 3 1 0 3 3 3 1 Exportin 1-like protein Sec10 PF07393.6 KII91464.1 - 9.3e-132 440.6 0.0 1.2e-131 440.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 KII91464.1 - 2.9e-06 26.8 0.3 5.7e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII91464.1 - 2e-05 24.1 0.6 0.00011 21.8 0.4 2.1 2 0 0 2 2 2 1 F-box-like RDV-p3 PF09231.5 KII91464.1 - 0.055 10.8 0.0 0.084 10.2 0.0 1.1 1 0 0 1 1 1 0 Rice dwarf virus p3 Rubella_E1 PF05748.6 KII91465.1 - 0.21 10.1 2.9 0.25 9.9 2.0 1.0 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 Mre11_DNA_bind PF04152.9 KII91468.1 - 1.5e-53 181.2 0.0 1.5e-53 181.2 0.0 2.4 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KII91468.1 - 2.5e-27 95.6 1.3 4e-27 94.9 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII91468.1 - 5.1e-07 29.6 0.2 2.6e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain IFT43 PF15305.1 KII91468.1 - 3.2 7.7 9.4 0.57 10.2 3.1 2.2 1 1 1 2 2 2 0 Intraflagellar transport protein 43 TPT PF03151.11 KII91469.1 - 8.2e-11 41.7 9.0 8.2e-11 41.7 6.2 3.1 2 1 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 KII91469.1 - 3.1e-05 24.0 34.1 0.00038 20.4 11.1 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KII91469.1 - 0.066 12.1 20.3 0.097 11.5 14.1 1.2 1 0 0 1 1 1 0 UAA transporter family UDPG_MGDP_dh_N PF03721.9 KII91470.1 - 8.4e-57 191.5 0.1 3.2e-56 189.6 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KII91470.1 - 7.7e-35 119.2 0.4 5.2e-34 116.5 0.2 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KII91470.1 - 2.2e-31 107.9 0.0 4.9e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 KII91470.1 - 0.0054 16.4 0.2 1.2 8.7 0.0 2.9 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 KII91470.1 - 0.046 13.5 0.2 3.4 7.4 0.0 2.8 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain OTCace PF00185.19 KII91470.1 - 0.066 13.0 0.1 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain F420_oxidored PF03807.12 KII91470.1 - 0.074 13.4 1.3 0.53 10.7 0.1 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 KII91472.1 - 3.5e-80 269.7 0.0 4.3e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 KII91473.1 - 1.2e-65 221.2 0.0 1.6e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KII91473.1 - 2.8e-05 23.1 0.0 4.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TAA-Trp-ring PF15401.1 KII91473.1 - 0.0076 16.4 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Polysacc_synt_2 PF02719.10 KII91473.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HTH_8 PF02954.14 KII91473.1 - 0.045 13.2 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family NAD_binding_10 PF13460.1 KII91473.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 KII91473.1 - 0.055 12.7 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 KII91474.1 - 3e-51 174.1 0.0 3.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KII91474.1 - 2.7e-06 26.5 0.0 8.4e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KII91474.1 - 4.3e-05 22.5 0.3 0.004 16.0 0.2 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KII91474.1 - 0.0012 17.6 0.0 0.0023 16.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DEAD PF00270.24 KII91475.1 - 4.9e-16 58.6 0.0 8.2e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Bromodomain PF00439.20 KII91475.1 - 2.5e-13 49.7 0.1 6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KII91475.1 - 3.9e-05 23.4 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII91475.1 - 0.16 11.8 0.0 0.48 10.2 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UME PF08064.8 KII91476.1 - 0.02 14.8 0.2 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 UME (NUC010) domain Peptidase_M24 PF00557.19 KII91477.1 - 2.8e-57 193.6 0.0 3.9e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KII91477.1 - 9.6e-19 67.1 0.0 1.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GFO_IDH_MocA PF01408.17 KII91478.1 - 3.1e-13 50.2 0.0 6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII91478.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain BPL_N PF09825.4 KII91479.1 - 1.6e-36 125.9 0.0 6.8e-35 120.5 0.0 2.4 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KII91479.1 - 1.4e-16 60.6 0.0 2.7e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ABC_transp_aux PF09822.4 KII91479.1 - 0.046 13.1 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system SNF2_N PF00176.18 KII91481.1 - 5.2e-75 252.0 0.2 9.4e-75 251.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII91481.1 - 2.4e-17 62.5 0.0 5.7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KII91481.1 - 0.00013 20.9 1.9 0.02 13.7 0.0 3.0 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 KII91481.1 - 0.037 13.4 1.0 1.4 8.2 0.0 3.1 3 0 0 3 3 3 0 DEAD_2 DUF2413 PF10310.4 KII91481.1 - 1.6 7.4 8.5 0.037 12.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) EST1_DNA_bind PF10373.4 KII91482.1 - 1.2e-33 116.5 0.0 1.8e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KII91482.1 - 2.4e-13 50.2 0.0 4.2e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 PAPS_reduct PF01507.14 KII91483.1 - 1.1e-26 93.6 0.0 4.1e-26 91.8 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family GCS PF03074.11 KII91484.1 - 3e-154 513.5 0.0 4.3e-124 414.3 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase Peptidase_M20 PF01546.23 KII91485.1 - 4.1e-30 104.6 0.0 7.2e-30 103.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KII91485.1 - 6.5e-14 51.6 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Aminotran_1_2 PF00155.16 KII91486.1 - 1.2e-52 179.1 0.0 3e-50 171.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KII91486.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.15 KII91486.1 - 0.011 14.3 0.0 0.021 13.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 KII91486.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF4165 PF13752.1 KII91487.1 - 0.14 11.9 0.0 6.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) F-box PF00646.28 KII91488.1 - 1.2e-05 24.7 0.1 1.2e-05 24.7 0.0 3.2 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.2 KII91488.1 - 0.012 15.3 0.0 0.012 15.3 0.0 2.7 3 0 0 3 3 3 0 F-box-like Zn_ribbon_2 PF12674.2 KII91488.1 - 4.9 7.5 7.9 1.7 9.0 0.1 3.0 3 0 0 3 3 3 0 Putative zinc ribbon domain ArfGap PF01412.13 KII91489.1 - 5.9e-40 135.7 0.4 9e-40 135.1 0.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NUDIX PF00293.23 KII91490.1 - 2.6e-12 46.5 0.0 3.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SUZ PF12752.2 KII91491.1 - 4e-13 49.6 0.3 4e-13 49.6 0.2 3.0 3 0 0 3 3 3 1 SUZ domain Dus PF01207.12 KII91492.1 - 5.2e-51 173.3 0.0 8.1e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KII91492.1 - 6.5e-05 22.5 5.2 0.00048 19.7 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Fungal_trans PF04082.13 KII91493.1 - 1.3e-32 112.7 0.0 2.6e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91493.1 - 5e-05 23.1 14.4 8.3e-05 22.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF775 PF05603.7 KII91494.1 - 7.9e-45 152.8 0.0 1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FA_desaturase PF00487.19 KII91495.1 - 2.5e-25 89.3 25.3 4.3e-25 88.6 17.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KII91495.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pro-kuma_activ PF09286.6 KII91496.1 - 1.2e-46 158.3 0.1 7.4e-46 155.7 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII91496.1 - 0.0025 17.0 1.1 0.0053 15.9 0.8 1.5 1 0 0 1 1 1 1 Subtilase family F-box PF00646.28 KII91497.1 - 0.0018 17.8 1.1 0.003 17.1 0.8 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII91497.1 - 0.0019 17.8 0.4 0.0027 17.4 0.3 1.2 1 0 0 1 1 1 1 F-box-like FA_desaturase PF00487.19 KII91499.1 - 3.3e-26 92.2 23.6 5.5e-26 91.5 16.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KII91499.1 - 7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) NAD_binding_5 PF07994.7 KII91501.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Epimerase PF01370.16 KII91502.1 - 7.6e-21 74.6 0.1 4.3e-20 72.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII91502.1 - 1.6e-17 63.1 0.0 2.5e-17 62.4 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KII91502.1 - 1.8e-13 50.8 0.2 7.9e-13 48.8 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII91502.1 - 1.1e-08 34.2 0.1 7.4e-07 28.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII91502.1 - 2.3e-05 23.7 0.2 4.2e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KII91502.1 - 0.0025 17.7 0.8 0.021 14.7 0.5 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KII91502.1 - 0.0057 15.5 0.1 0.0089 14.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Prenylcys_lyase PF07156.9 KII91502.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase WD40 PF00400.27 KII91503.1 - 3.8e-34 115.3 7.6 1e-07 31.5 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KII91503.1 - 0.027 13.2 0.0 8.4 5.0 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Aminotran_1_2 PF00155.16 KII91504.1 - 1.6e-38 132.6 0.0 2.1e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_11 PF13414.1 KII91505.1 - 1e-18 66.7 2.3 2.5e-12 46.2 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KII91505.1 - 4.4e-06 26.1 3.4 0.0053 16.5 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII91505.1 - 0.0046 17.5 4.4 0.73 10.5 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII91505.1 - 0.014 15.5 1.1 7.2 7.0 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KII91505.1 - 0.04 14.2 5.1 1.7 9.0 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KII91505.1 - 0.11 12.3 0.4 16 5.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII91505.1 - 0.48 10.1 4.1 5.2 6.8 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KII91505.1 - 0.77 9.7 8.1 5.2 7.0 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII91505.1 - 1.3 9.8 5.5 61 4.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1482 PF07358.6 KII91506.1 - 0.065 12.8 0.2 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) TPR_11 PF13414.1 KII91507.1 - 1.1e-17 63.4 11.8 5.2e-16 58.0 1.4 3.3 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 KII91507.1 - 1.1e-08 34.2 13.3 0.0069 16.2 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII91507.1 - 1.8e-05 24.1 8.0 1.3 8.7 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KII91507.1 - 0.0012 18.7 7.6 0.0092 15.8 0.4 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII91507.1 - 0.015 15.8 11.6 1.3 9.8 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KII91507.1 - 0.035 14.3 6.3 0.068 13.4 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KII91507.1 - 0.76 9.6 6.7 0.21 11.5 0.2 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 KII91507.1 - 1.7 9.3 12.9 5.4 7.8 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DAO PF01266.19 KII91508.1 - 3.4e-34 118.3 1.2 4.3e-34 117.9 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII91508.1 - 0.01 15.8 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_6 PF12697.2 KII91511.1 - 1.4e-19 70.9 5.6 1.7e-19 70.5 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII91511.1 - 2.5e-07 30.5 0.1 6.6e-07 29.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 KII91512.1 - 1e-65 222.0 0.0 2.1e-65 221.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 KII91512.1 - 0.061 12.6 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 KII91513.1 - 3.6e-66 223.5 0.0 6.5e-66 222.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Copper-fist PF00649.13 KII91514.1 - 7.3e-21 73.0 0.5 7.3e-21 73.0 0.3 3.7 3 1 1 4 4 4 2 Copper fist DNA binding domain HTH_15 PF12324.3 KII91514.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase F-box-like PF12937.2 KII91518.1 - 0.025 14.3 0.2 0.059 13.1 0.2 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KII91519.1 - 0.06 13.0 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 F-box-like Fer2 PF00111.22 KII91520.1 - 2.3e-11 43.2 0.1 3.4e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pro-kuma_activ PF09286.6 KII91521.1 - 2.9e-37 127.8 0.0 8.2e-37 126.4 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII91521.1 - 7.6e-06 25.2 1.8 1.3e-05 24.5 1.2 1.3 1 0 0 1 1 1 1 Subtilase family MMR_HSR1 PF01926.18 KII91522.1 - 1.1e-05 25.3 0.1 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KII91522.1 - 4.3e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KII91522.1 - 0.00011 21.2 0.0 0.07 12.1 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_16 PF13191.1 KII91522.1 - 0.0032 17.4 0.1 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KII91522.1 - 0.0042 16.2 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KII91522.1 - 0.0076 17.0 0.0 0.016 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KII91522.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KII91522.1 - 0.022 14.1 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KII91522.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII91522.1 - 0.036 13.7 0.2 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 KII91522.1 - 0.043 13.3 0.1 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KII91522.1 - 0.043 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 KII91522.1 - 0.045 13.1 0.2 0.15 11.4 0.0 1.9 3 0 0 3 3 3 0 Ras family AIG1 PF04548.11 KII91522.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.22 KII91522.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KII91522.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.1 KII91522.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 KII91522.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 KII91522.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DnaJ PF00226.26 KII91523.1 - 3.2e-17 62.0 0.2 1.1e-16 60.3 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Opi1 PF08618.5 KII91523.1 - 4.9 5.9 13.7 6.7 5.5 9.5 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DNA_pol_A_exo1 PF01612.15 KII91524.1 - 5.7e-14 51.9 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease HTH_40 PF14493.1 KII91524.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PQ-loop PF04193.9 KII91525.1 - 5.4e-18 64.2 6.0 1.1e-09 37.6 0.8 3.7 4 0 0 4 4 4 2 PQ loop repeat DUF3328 PF11807.3 KII91525.1 - 0.11 12.1 7.6 0.44 10.1 0.8 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3328) Adap_comp_sub PF00928.16 KII91526.1 - 1.4e-90 303.0 0.0 1.9e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KII91526.1 - 8.8e-07 28.7 0.3 1.6e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KII91526.1 - 0.00077 18.7 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mon1 PF03164.9 KII91526.1 - 0.0036 15.9 0.0 0.0056 15.3 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 SH3_5 PF08460.5 KII91526.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain 4HBT PF03061.17 KII91529.1 - 7e-07 29.2 0.1 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily PHP PF02811.14 KII91530.1 - 2.6e-11 43.6 0.0 4.8e-11 42.7 0.0 1.3 1 1 0 1 1 1 1 PHP domain Rnk_N PF14760.1 KII91530.1 - 0.029 14.4 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 Rnk N-terminus DUF3039 PF11238.3 KII91531.1 - 0.007 15.7 1.2 0.011 15.2 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) TerY-C PF15616.1 KII91531.1 - 0.027 14.4 2.6 0.028 14.3 1.8 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain DUF1688 PF07958.6 KII91532.1 - 1.3e-161 537.8 0.0 1.5e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.1 KII91533.1 - 5e-09 35.0 24.9 6.8e-08 31.3 16.7 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 KII91533.1 - 9.8 6.2 10.7 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) ETF_QO PF05187.8 KII91534.1 - 3.7e-28 97.7 0.0 1.8e-26 92.2 0.0 2.3 1 1 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KII91534.1 - 1.5e-07 30.6 0.0 3.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII91534.1 - 3.4e-07 30.1 0.0 9.4e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII91534.1 - 1.2e-05 24.4 1.1 8.8e-05 21.5 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KII91534.1 - 2.3e-05 24.5 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KII91534.1 - 3.8e-05 23.6 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII91534.1 - 8.1e-05 21.8 0.0 0.0027 16.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KII91534.1 - 0.00017 20.2 0.6 0.00024 19.6 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 KII91534.1 - 0.00037 20.2 0.1 0.00075 19.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KII91534.1 - 0.00041 19.5 0.1 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KII91534.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KII91534.1 - 0.0029 16.5 0.2 0.0044 15.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 KII91534.1 - 0.0055 17.0 0.4 0.019 15.3 0.3 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 KII91534.1 - 0.013 14.1 0.2 0.022 13.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_10 PF13237.1 KII91534.1 - 0.09 12.5 0.6 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.22 KII91534.1 - 0.091 13.1 0.3 3 8.3 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII91534.1 - 0.11 11.3 0.1 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.2 KII91534.1 - 3 7.9 5.0 0.43 10.5 0.5 1.9 2 0 0 2 2 1 0 4Fe-4S binding domain Methyltransf_10 PF05971.7 KII91536.1 - 6.1e-69 232.4 0.0 7.6e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KII91536.1 - 8.7e-06 25.7 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII91536.1 - 0.0021 17.2 0.0 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KII91536.1 - 0.0041 17.6 0.0 0.0086 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII91536.1 - 0.0044 16.4 0.0 0.019 14.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain DUF633 PF04816.7 KII91536.1 - 0.029 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_11 PF08241.7 KII91536.1 - 0.048 14.1 0.0 0.092 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KII91537.1 - 1.2e-65 221.8 0.0 2.9e-65 220.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII91538.1 - 8.6e-69 232.2 0.0 1.7e-68 231.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KII91540.1 - 2.8e-16 59.8 0.1 4.7e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91540.1 - 6.9e-05 22.5 0.1 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII91540.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UQ_con PF00179.21 KII91541.1 - 4.1e-49 165.6 0.0 4.9e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KII91541.1 - 1.1e-08 34.9 0.2 1.8e-06 27.7 0.0 2.1 1 1 1 2 2 2 2 Prokaryotic E2 family B HAT PF02184.11 KII91542.1 - 1.4e-24 85.5 49.2 7.6e-08 31.9 1.8 14.2 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KII91542.1 - 2.2e-23 80.6 25.1 0.0013 19.1 0.0 12.2 3 2 10 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.1 KII91542.1 - 5.3e-16 58.7 0.1 0.05 13.9 0.0 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KII91542.1 - 6.4e-14 52.1 19.2 0.0011 19.6 0.0 8.0 8 2 2 10 10 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KII91542.1 - 6.4e-12 44.4 4.7 1.6 8.8 0.0 8.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 KII91542.1 - 2.6e-10 39.7 1.7 0.2 11.3 0.0 6.1 5 2 2 7 7 7 4 TPR repeat TPR_7 PF13176.1 KII91542.1 - 9.2e-08 31.3 11.4 4.6 7.2 0.0 9.1 11 0 0 11 11 10 2 Tetratricopeptide repeat SNAP PF14938.1 KII91542.1 - 1.9e-07 30.5 1.2 0.00018 20.7 0.3 3.6 4 0 0 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.1 KII91542.1 - 3.1e-06 26.4 19.2 0.016 14.2 4.3 5.6 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KII91542.1 - 1.4e-05 24.8 0.3 0.049 13.8 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII91542.1 - 6.4e-05 22.3 0.7 46 3.8 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KII91542.1 - 0.00032 20.5 12.0 0.55 10.1 0.0 6.7 5 3 1 6 6 6 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KII91542.1 - 0.0019 17.9 14.8 0.012 15.3 0.5 5.7 3 3 3 6 6 6 1 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 KII91542.1 - 0.082 13.4 11.7 90 3.8 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 KII91542.1 - 0.12 12.4 2.2 4.1 7.5 0.1 4.0 5 0 0 5 5 5 0 c-SKI Smad4 binding domain IncA PF04156.9 KII91543.1 - 0.044 13.3 8.7 0.014 14.9 4.4 1.4 1 1 1 2 2 2 0 IncA protein zf-DHHC PF01529.15 KII91543.1 - 2.2 7.6 6.8 3.2 7.1 4.7 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DnaJ PF00226.26 KII91544.1 - 2.2e-16 59.3 4.7 2.2e-16 59.3 3.3 1.7 2 0 0 2 2 2 1 DnaJ domain TGT PF01702.13 KII91545.1 - 4.4e-26 91.6 0.0 4.7e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Amidase PF01425.16 KII91546.1 - 7.6e-75 252.4 0.1 7.3e-74 249.1 0.0 1.9 1 1 0 1 1 1 1 Amidase PGPGW PF09656.5 KII91546.1 - 2.4 7.5 5.7 5 6.4 0.3 2.6 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) His_Phos_2 PF00328.17 KII91547.1 - 5.6e-45 154.1 0.0 6.9e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3684 PF12449.3 KII91548.1 - 0 1142.9 0.0 0 1142.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Spo7 PF03907.8 KII91549.1 - 1.4e-13 50.9 2.9 1.4e-13 50.9 2.0 2.8 2 1 0 2 2 2 1 Spo7-like protein Tmemb_18A PF09771.4 KII91549.1 - 0.023 14.6 0.4 0.14 12.1 0.3 2.0 1 1 0 1 1 1 0 Transmembrane protein 188 DUF2207 PF09972.4 KII91549.1 - 0.14 10.7 0.2 0.21 10.1 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.17 KII91550.1 - 7.5e-66 222.5 0.0 1.7e-65 221.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 CBM_1 PF00734.13 KII91554.1 - 1.9e-11 43.4 13.4 1.9e-11 43.4 9.3 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain CFEM PF05730.6 KII91555.1 - 3.6e-13 49.1 12.4 3.6e-13 49.1 8.6 1.6 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.6 KII91555.1 - 1.6 6.4 11.0 1.7 6.3 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L34e PF01199.13 KII91556.1 - 1.8e-38 130.6 3.5 2.5e-38 130.1 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 KII91556.1 - 0.027 14.1 3.0 2.6 7.7 0.1 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain EndIII_4Fe-2S PF10576.4 KII91556.1 - 0.22 11.7 2.0 0.55 10.5 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ribosomal_L31e PF01198.14 KII91557.1 - 2e-36 123.5 3.8 2.6e-36 123.1 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e EHN PF06441.7 KII91559.1 - 1.5e-33 115.0 0.3 3e-32 110.8 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII91559.1 - 6.4e-09 36.0 0.7 1.5e-08 34.8 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII91559.1 - 3.9e-05 23.3 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CAP59_mtransfer PF11735.3 KII91560.1 - 7.9e-70 234.8 0.0 1.1e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RPN7 PF10602.4 KII91561.1 - 4.5e-41 140.1 0.0 8.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KII91561.1 - 2.6e-14 53.3 0.0 8.6e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 KII91561.1 - 0.00012 21.7 1.5 0.82 9.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII91561.1 - 0.00035 20.1 0.0 0.31 10.9 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII91561.1 - 0.0027 17.2 3.6 0.27 10.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII91561.1 - 0.0061 16.1 0.2 0.82 9.3 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 KII91561.1 - 0.0091 15.9 0.1 0.84 9.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII91561.1 - 0.022 14.5 0.1 2.7 7.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII91561.1 - 0.044 14.2 0.2 6.7 7.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII91561.1 - 0.83 10.4 6.6 27 5.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop53 PF07767.6 KII91562.1 - 3.4e-76 256.7 11.3 4.3e-76 256.4 7.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BTB PF00651.26 KII91563.1 - 2e-10 40.6 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII91564.1 - 0.049 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF718 PF05336.8 KII91566.1 - 2.7e-28 97.8 0.0 3.1e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Aminotran_1_2 PF00155.16 KII91569.1 - 5.7e-36 124.2 0.0 7.1e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KII91569.1 - 0.038 12.2 0.0 0.08 11.2 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme F-box-like PF12937.2 KII91570.1 - 0.07 12.8 0.4 0.07 12.8 0.3 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KII91570.1 - 0.74 9.5 5.3 0.13 11.9 0.8 2.0 2 0 0 2 2 2 0 F-box domain RNA_Me_trans PF04252.8 KII91571.1 - 2.7e-35 121.5 0.0 3.6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.20 KII91572.1 - 2.1e-61 207.3 0.0 3.4e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91572.1 - 4.6e-44 150.4 0.0 8.4e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 KII91572.1 - 1.4e-19 70.2 0.0 2.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 KII91572.1 - 3.7e-07 29.3 0.0 5.7e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII91572.1 - 0.001 18.8 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Alginate_lyase PF05426.7 KII91574.1 - 4e-58 196.9 3.0 7.3e-58 196.0 2.1 1.4 1 0 0 1 1 1 1 Alginate lyase Pneumo_att_G PF05539.6 KII91576.1 - 1.3 8.2 5.5 1.4 8.2 3.8 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribosomal_L28 PF00830.14 KII91581.1 - 8.1e-23 80.0 2.3 1.1e-22 79.5 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L28 family NT-C2 PF10358.4 KII91583.1 - 1e-17 63.9 0.0 2.7e-16 59.3 0.0 2.2 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins GWT1 PF06423.7 KII91585.1 - 5.4e-35 120.4 0.0 3.4e-34 117.8 0.0 2.4 2 1 0 2 2 2 1 GWT1 YIEGIA PF14045.1 KII91585.1 - 0.094 11.3 0.2 0.16 10.5 0.2 1.3 1 0 0 1 1 1 0 YIEGIA protein AA_permease_2 PF13520.1 KII91586.1 - 8.5e-52 176.1 52.9 1e-51 175.8 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII91586.1 - 7.8e-23 80.5 48.0 1.3e-22 79.8 33.3 1.2 1 1 0 1 1 1 1 Amino acid permease COX2-transmemb PF09125.5 KII91586.1 - 7 6.2 9.6 5.8 6.5 0.0 3.7 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane DUF607 PF04678.8 KII91587.1 - 3e-42 144.5 0.1 6.3e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF607 DUF4193 PF13834.1 KII91587.1 - 0.23 11.6 6.4 0.45 10.7 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) DIOX_N PF14226.1 KII91589.1 - 3.2e-18 66.3 0.0 6.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII91589.1 - 1e-13 51.4 0.0 1e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BetaGal_dom2 PF10435.4 KII91589.1 - 0.054 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 KdgM PF06178.8 KII91589.1 - 0.055 12.9 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) DIOX_N PF14226.1 KII91590.1 - 9.9e-15 55.0 0.0 2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII91590.1 - 7.1e-11 42.2 0.0 2.4e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LPAM_1 PF08139.7 KII91591.1 - 0.094 12.9 1.0 0.29 11.4 0.7 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_S10 PF00450.17 KII91592.1 - 6.7e-95 318.6 2.8 8e-95 318.4 2.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1246 PF06849.7 KII91592.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) PhyH PF05721.8 KII91593.1 - 1.6e-10 41.4 0.0 2.8e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cellulase PF00150.13 KII91594.1 - 2.2e-13 50.0 0.0 1.6e-07 30.8 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) APH PF01636.18 KII91595.1 - 4.7e-14 52.7 0.3 2.1e-13 50.5 0.0 2.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Hexokinase_2 PF03727.11 KII91596.1 - 4.9e-81 271.5 0.0 6.9e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KII91596.1 - 3.2e-70 235.6 0.0 4.8e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1731 PF08338.6 KII91596.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Ribosomal_L14 PF00238.14 KII91597.1 - 3.9e-43 146.0 2.0 4.4e-43 145.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Harakiri PF15196.1 KII91597.1 - 0.041 14.1 0.5 0.061 13.5 0.4 1.3 1 0 0 1 1 1 0 Activator of apoptosis harakiri WD40 PF00400.27 KII91598.1 - 1.3e-36 123.1 1.3 5.5e-09 35.5 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KII91598.1 - 2.4e-05 24.1 0.1 0.073 12.7 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KII91598.1 - 0.0026 16.6 0.0 1.2 7.8 0.0 2.8 3 0 0 3 3 3 2 Coatomer WD associated region BBS2_Mid PF14783.1 KII91598.1 - 0.2 11.4 0.0 0.74 9.6 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Proteasome_A_N PF10584.4 KII91598.1 - 5.9 6.3 5.7 28 4.1 0.1 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature eIF-5_eIF-2B PF01873.12 KII91599.1 - 5.4e-45 152.0 0.1 8.2e-45 151.4 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 KII91599.1 - 0.0033 16.7 0.2 0.0065 15.7 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.7 KII91599.1 - 0.084 12.3 0.1 13 5.3 0.0 2.5 2 0 0 2 2 2 0 HypF finger ATP-synt PF00231.14 KII91600.1 - 1.9e-73 247.3 2.4 2.2e-73 247.1 1.7 1.0 1 0 0 1 1 1 1 ATP synthase Glucosamine_iso PF01182.15 KII91601.1 - 3.2e-23 82.5 0.0 4.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.7 KII91601.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain UPF0029 PF01205.14 KII91602.1 - 4.9e-25 87.3 0.0 6.1e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 But2 PF09792.4 KII91603.1 - 0.00046 19.9 0.0 0.0053 16.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Epimerase PF01370.16 KII91604.1 - 4e-17 62.4 0.0 1.1e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII91604.1 - 2.7e-12 47.0 0.7 4.6e-12 46.3 0.5 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII91604.1 - 8.8e-12 44.3 0.0 1.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KII91604.1 - 2.7e-10 39.6 0.1 4.1e-09 35.7 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KII91604.1 - 1.5e-08 34.2 0.5 2.2e-08 33.6 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KII91604.1 - 5.6e-08 32.8 1.9 1.2e-07 31.7 1.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KII91604.1 - 7.8e-06 24.9 0.0 1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KII91604.1 - 4.1e-05 23.3 1.5 0.0001 22.0 1.0 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KII91604.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MaoC_dehydratas PF01575.14 KII91605.1 - 1.9e-25 88.6 0.0 3.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KII91605.1 - 4.1e-07 29.8 0.0 2.2e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF3328 PF11807.3 KII91606.1 - 4.9e-26 91.7 0.2 7.1e-26 91.2 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) BAALC_N PF06989.7 KII91606.1 - 0.025 14.8 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 BAALC N-terminus HSP70 PF00012.15 KII91607.1 - 2.7e-40 137.8 0.0 3.2e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Pyr_redox_3 PF13738.1 KII91608.1 - 4.5e-23 82.3 0.1 8.5e-22 78.2 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII91608.1 - 3.9e-21 74.8 0.0 1.2e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KII91608.1 - 1.8e-15 56.7 0.0 1.9e-09 36.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII91608.1 - 4.8e-11 42.9 0.0 2.2e-08 34.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII91608.1 - 3.7e-08 33.6 0.2 0.0025 18.1 0.0 3.8 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII91608.1 - 4.6e-05 23.3 0.0 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KII91608.1 - 0.00054 19.1 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KII91608.1 - 0.002 17.1 0.4 1.5 7.6 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KII91608.1 - 0.0093 15.0 0.0 0.036 13.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KII91608.1 - 0.039 13.7 1.8 4.2 7.1 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding SnoaL_2 PF12680.2 KII91608.1 - 0.046 14.1 2.4 0.25 11.7 0.2 2.5 2 0 0 2 2 2 0 SnoaL-like domain 3HCDH_N PF02737.13 KII91608.1 - 0.074 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SnoaL_4 PF13577.1 KII91608.1 - 0.12 12.3 0.4 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain TauD PF02668.11 KII91609.1 - 7.8e-54 183.0 2.3 1e-53 182.6 1.3 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KII91609.1 - 0.00043 20.6 0.0 0.00092 19.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KII91609.1 - 0.0085 15.0 0.1 0.016 14.1 0.1 1.4 1 1 0 1 1 1 1 CsiD Abhydro_lipase PF04083.11 KII91610.1 - 6.7e-22 76.6 0.0 1.6e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KII91610.1 - 1.8e-17 63.7 0.3 2.8e-17 63.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII91610.1 - 1.8e-10 41.1 0.8 3.8e-10 40.0 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII91610.1 - 7e-07 29.0 0.0 2.5e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KII91610.1 - 0.00063 19.2 0.0 0.034 13.6 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Kelch_3 PF13415.1 KII91611.1 - 5.4e-08 32.7 0.1 0.036 14.2 0.0 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KII91611.1 - 5.8e-07 29.4 0.1 0.079 13.1 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 KII91611.1 - 2.8e-06 27.0 0.1 0.99 9.2 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KII91611.1 - 5e-06 25.9 0.1 0.096 12.2 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 KII91611.1 - 0.0005 19.7 2.1 1.4 8.7 0.0 3.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 KII91611.1 - 0.00071 19.4 0.0 1 9.3 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Pyr_redox_3 PF13738.1 KII91612.1 - 1e-21 77.9 0.1 1.4e-20 74.2 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KII91612.1 - 8.6e-21 73.7 0.0 3.1e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KII91612.1 - 3e-15 55.9 0.0 1.1e-09 37.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII91612.1 - 3.8e-11 43.2 0.0 1.5e-08 34.7 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII91612.1 - 1.9e-08 34.5 0.1 0.0025 18.1 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII91612.1 - 4.3e-05 23.4 0.0 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII91612.1 - 5e-05 22.3 0.2 0.17 10.7 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KII91612.1 - 0.00052 19.2 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KII91612.1 - 0.0043 16.1 0.0 0.035 13.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KII91612.1 - 0.065 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KII91612.1 - 0.073 12.8 1.7 4.2 7.1 0.0 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 KII91612.1 - 0.17 10.9 0.1 3 6.8 0.0 2.3 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 KII91612.1 - 0.19 10.1 0.0 1.7 7.0 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Nup54 PF13874.1 KII91613.1 - 1e-34 119.1 7.6 2.7e-34 117.8 5.3 1.7 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KII91613.1 - 7.9e-28 96.9 150.1 1.1e-16 61.1 37.8 3.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region TcdB_N PF12918.2 KII91613.1 - 0.064 13.3 0.3 0.22 11.5 0.2 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain FlaC_arch PF05377.6 KII91613.1 - 0.11 12.4 0.6 21 5.0 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HWE_HK PF07536.9 KII91613.1 - 0.43 11.0 8.2 0.88 10.0 3.3 2.8 3 0 0 3 3 3 0 HWE histidine kinase DivIC PF04977.10 KII91613.1 - 0.68 9.4 3.0 0.48 9.9 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Fungal_trans PF04082.13 KII91614.1 - 2.7e-20 72.3 0.0 4e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91614.1 - 2.1e-08 33.9 10.2 4.2e-08 32.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med4 PF10018.4 KII91614.1 - 0.033 13.5 0.1 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Pro_isomerase PF00160.16 KII91615.1 - 1.5e-42 145.4 0.0 2.2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KII91615.1 - 2.8e-08 33.2 5.8 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KII91615.1 - 0.00061 19.5 6.8 0.059 13.3 1.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII91615.1 - 0.069 13.8 9.2 0.18 12.4 4.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KII91615.1 - 0.4 11.0 2.8 14 6.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII91615.1 - 0.48 10.1 4.2 2.6 7.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII91615.1 - 1 9.9 5.1 52 4.6 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KII91615.1 - 1.4 9.6 11.0 6.5 7.5 4.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 KII91616.1 - 6.4e-17 62.3 0.0 1.3e-16 61.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KII91616.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.1 KII91616.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like MepB PF08877.5 KII91616.1 - 0.2 11.1 0.0 0.59 9.6 0.0 1.7 1 0 0 1 1 1 0 MepB protein HABP4_PAI-RBP1 PF04774.10 KII91617.1 - 7.4e-05 23.2 2.1 9.9e-05 22.8 1.5 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family AAA_17 PF13207.1 KII91619.1 - 6.2e-05 23.7 0.0 0.00013 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KII91619.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 KII91619.1 - 0.0027 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KII91619.1 - 0.0046 16.5 0.0 0.078 12.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Arf PF00025.16 KII91619.1 - 0.0058 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KII91619.1 - 0.0078 16.7 0.0 0.05 14.1 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KII91619.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KII91619.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KII91619.1 - 0.034 13.1 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Septin G-alpha PF00503.15 KII91619.1 - 0.068 11.8 0.0 1.4 7.5 0.0 2.2 2 1 0 2 2 2 0 G-protein alpha subunit AAA PF00004.24 KII91619.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.6 KII91619.1 - 0.09 11.6 0.1 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Rad51 AAA_18 PF13238.1 KII91619.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4131 PF13567.1 KII91621.1 - 0.0075 15.6 0.1 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF624 PF04854.9 KII91621.1 - 0.049 13.4 0.2 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DUF3941 PF13081.1 KII91622.1 - 1.1 9.3 5.5 3.6 7.6 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3941) CENP-B_dimeris PF09026.5 KII91623.1 - 0.17 12.1 3.8 0.19 11.9 2.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Anophelin PF10731.4 KII91623.1 - 6.9 6.8 9.0 8.3 6.5 6.1 1.3 1 1 0 1 1 1 0 Thrombin inhibitor from mosquito BTB PF00651.26 KII91624.1 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_6 PF12697.2 KII91625.1 - 2e-07 31.1 0.3 4.1e-07 30.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII91625.1 - 2.5e-07 30.5 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KII91625.1 - 1.6e-05 25.2 0.1 6.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 KII91625.1 - 3.4e-05 23.5 1.2 4.6e-05 23.1 0.1 1.9 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.15 KII91625.1 - 0.00047 19.7 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 KII91625.1 - 0.0028 17.0 0.0 0.0066 15.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.9 KII91625.1 - 0.0044 16.3 0.0 0.012 14.9 0.0 1.7 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Ndc1_Nup PF09531.5 KII91625.1 - 0.02 13.3 5.1 0.19 10.1 0.8 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Lipase_3 PF01764.20 KII91625.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KII91625.1 - 0.038 13.5 0.1 0.14 11.7 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold UPF0227 PF05728.7 KII91625.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 KII91625.1 - 0.27 10.0 6.7 1.6 7.5 4.7 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) NARP1 PF12569.3 KII91625.1 - 2.4 6.8 10.3 3.6 6.2 7.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF106 PF01956.11 KII91625.1 - 3.4 7.1 4.6 7.7 6.0 3.2 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 RR_TM4-6 PF06459.7 KII91625.1 - 6.1 6.6 13.7 0.84 9.4 4.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NinG PF05766.7 KII91625.1 - 8.3 6.1 11.4 6.1 6.5 5.7 2.0 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein TFIIS_C PF01096.13 KII91626.1 - 5.5e-13 48.3 1.5 5.5e-13 48.3 1.0 2.8 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KII91626.1 - 3.8e-11 42.4 1.1 3.8e-11 42.4 0.8 3.3 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 KII91626.1 - 0.0026 17.9 0.2 0.0026 17.9 0.2 2.2 2 1 0 2 2 2 1 Restriction alleviation protein Lar Zn_Tnp_IS1 PF03811.8 KII91626.1 - 0.019 14.4 0.4 0.019 14.4 0.3 2.6 3 0 0 3 3 3 0 InsA N-terminal domain UPF0547 PF10571.4 KII91626.1 - 0.023 14.3 9.8 0.046 13.4 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Zn_ribbon_recom PF13408.1 KII91626.1 - 0.049 13.8 6.4 1.1 9.5 0.6 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.1 KII91626.1 - 0.062 12.8 7.4 1.9 8.0 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain GFA PF04828.9 KII91626.1 - 0.069 13.0 6.0 2.4 8.1 0.3 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.2 KII91626.1 - 0.073 12.8 10.5 0.29 10.9 2.0 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KII91626.1 - 0.081 12.9 10.6 0.39 10.7 0.8 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain DUF2387 PF09526.5 KII91626.1 - 0.14 12.0 0.3 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 KII91626.1 - 0.16 11.6 9.1 0.22 11.2 0.8 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like PhnA_Zn_Ribbon PF08274.7 KII91626.1 - 0.21 11.3 6.0 0.73 9.6 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-ISL3 PF14690.1 KII91626.1 - 0.31 11.1 0.1 0.31 11.1 0.1 3.3 2 2 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0515 PF15135.1 KII91626.1 - 0.38 9.7 2.5 3.5 6.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 zf-ribbon_3 PF13248.1 KII91626.1 - 0.38 10.0 8.1 1.8 7.9 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KII91626.1 - 0.53 9.8 6.0 3.4 7.2 0.1 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-RING_3 PF14369.1 KII91626.1 - 0.54 10.2 7.9 3.5 7.7 0.1 3.1 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 KII91626.1 - 0.64 9.8 10.3 4.7 7.1 1.3 3.1 2 2 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 KII91626.1 - 1.2 8.6 7.0 29 4.2 0.9 3.4 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_4 PF13717.1 KII91626.1 - 1.5 8.5 10.1 5.4 6.7 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KII91626.1 - 1.6 8.7 8.5 12 5.9 0.0 3.7 4 0 0 4 4 4 0 Zinc ribbon domain zf-CHY PF05495.7 KII91626.1 - 2 8.6 9.9 7.3 6.8 1.0 2.7 2 1 0 2 2 2 0 CHY zinc finger DUF1936 PF09151.5 KII91626.1 - 2.2 7.8 6.0 15 5.1 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1936) zinc_ribbon_5 PF13719.1 KII91626.1 - 2.3 7.8 10.0 5.8 6.5 0.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Rpr2 PF04032.11 KII91626.1 - 2.9 7.8 9.8 28 4.6 6.8 2.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain IBR PF01485.16 KII91626.1 - 3.3 7.6 9.6 3.3e+02 1.2 6.6 2.6 1 1 0 1 1 1 0 IBR domain FYVE PF01363.16 KII91626.1 - 3.5 7.6 8.8 6.6 6.7 0.6 2.4 2 1 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.17 KII91626.1 - 3.8 7.3 8.8 0.15 11.8 0.4 2.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.15 KII91626.1 - 5 7.0 8.3 45 4.0 0.0 3.8 4 0 0 4 4 4 0 Rubredoxin PHD PF00628.24 KII91626.1 - 7.1 6.4 10.5 1.3 8.7 0.8 2.8 2 1 0 2 2 2 0 PHD-finger Ribosomal_L27e PF01777.13 KII91627.1 - 1.5e-34 117.9 0.6 2.1e-34 117.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family PfkB PF00294.19 KII91628.1 - 2.8e-34 118.6 0.0 3.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4048 PF13257.1 KII91628.1 - 0.014 15.0 0.2 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) BTB PF00651.26 KII91629.1 - 3.8e-05 23.6 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_22 PF03901.12 KII91630.1 - 7.9e-14 51.4 1.1 1e-13 51.1 0.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.12 KII91631.1 - 8.2e-15 54.7 0.0 8.8e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Autophagy_N PF03986.8 KII91631.1 - 0.045 13.5 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Cyt-b5 PF00173.23 KII91632.1 - 3.7e-21 74.7 0.0 7.4e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KII91632.1 - 9.9e-07 29.1 19.5 9.9e-07 29.1 13.5 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF543 PF04418.7 KII91635.1 - 7.2e-28 96.3 0.1 8.1e-28 96.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-C2HC_2 PF13913.1 KII91635.1 - 0.14 11.8 0.2 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type BRO1 PF03097.13 KII91636.1 - 2.7e-113 378.5 0.0 4.2e-113 377.9 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KII91636.1 - 1.6e-61 207.9 1.6 2.6e-61 207.1 1.1 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Septin PF00735.13 KII91637.1 - 6.3e-05 22.1 0.1 0.00059 18.9 0.1 2.2 1 1 0 1 1 1 1 Septin Miro PF08477.8 KII91637.1 - 0.00011 22.6 0.0 0.00047 20.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KII91637.1 - 0.00015 21.6 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KII91637.1 - 0.00071 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KII91637.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 KII91637.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KII91637.1 - 0.0084 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.17 KII91637.1 - 0.013 14.9 0.1 0.14 11.5 0.1 2.3 1 1 0 1 1 1 0 Ras family AAA_18 PF13238.1 KII91637.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KII91637.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KII91637.1 - 0.021 15.6 0.2 0.056 14.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KII91637.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KII91637.1 - 0.023 14.8 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KII91637.1 - 0.028 14.2 0.4 0.089 12.6 0.3 1.7 1 1 0 1 1 1 0 Dynamin family AAA_15 PF13175.1 KII91637.1 - 0.044 12.8 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 KII91637.1 - 0.065 12.3 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MobB PF03205.9 KII91637.1 - 0.087 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.18 KII91637.1 - 0.089 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 KII91637.1 - 0.089 12.9 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AIG1 PF04548.11 KII91637.1 - 0.093 11.8 0.3 0.16 11.0 0.2 1.5 1 1 0 1 1 1 0 AIG1 family AAA PF00004.24 KII91637.1 - 0.1 12.7 0.0 0.53 10.4 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KII91637.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KII91637.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KII91637.1 - 0.12 11.2 0.1 0.49 9.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.1 KII91637.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KII91637.1 - 0.12 11.7 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 KII91637.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 KII91637.1 - 0.51 8.9 1.4 22 3.5 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit PNP_UDP_1 PF01048.15 KII91639.1 - 3.8e-36 124.2 0.6 5.2e-36 123.7 0.4 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily 2OG-FeII_Oxy_3 PF13640.1 KII91641.1 - 4.9e-10 39.8 0.2 8.3e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KII91641.1 - 0.00016 21.2 0.2 0.00032 20.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 KII91641.1 - 0.022 13.5 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein WD40 PF00400.27 KII91642.1 - 9.3e-11 41.1 15.9 5.6e-05 22.8 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat PHD PF00628.24 KII91642.1 - 0.12 12.0 7.4 0.57 9.9 2.6 2.6 2 0 0 2 2 2 0 PHD-finger FMO-like PF00743.14 KII91643.1 - 8.2e-23 80.3 0.0 1.2e-10 40.2 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII91643.1 - 4.7e-11 43.1 0.1 1.4e-09 38.3 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII91643.1 - 2.4e-07 30.6 0.1 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII91643.1 - 1.7e-06 28.0 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII91643.1 - 0.00078 18.4 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KII91643.1 - 0.00083 19.1 0.1 0.0061 16.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KII91643.1 - 0.0018 16.7 0.0 0.0039 15.7 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KII91643.1 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KII91643.1 - 0.002 17.2 0.2 0.0052 15.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 KII91643.1 - 0.0025 16.8 0.2 0.041 12.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KII91643.1 - 0.0044 16.1 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KII91643.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MoeA_N PF03453.12 KII91643.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) Rap1-DNA-bind PF09197.5 KII91644.1 - 0.00073 20.0 8.4 0.11 13.0 0.0 3.5 3 1 0 3 3 3 2 Rap1, DNA-binding Myb_DNA-bind_2 PF08914.6 KII91644.1 - 0.019 14.7 3.4 7.1 6.5 0.1 3.4 3 0 0 3 3 3 0 Rap1 Myb domain Iso_dh PF00180.15 KII91645.1 - 1.6e-70 237.7 0.0 1.9e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 KII91646.1 - 3.5e-13 49.0 12.2 1.9e-12 46.5 8.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 KII91646.1 - 0.97 9.4 9.4 0.5 10.4 3.6 2.6 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) 2OG-FeII_Oxy_3 PF13640.1 KII91647.1 - 1.4e-09 38.3 0.1 2.5e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KII91647.1 - 0.0018 17.8 0.4 0.0039 16.8 0.3 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Git3 PF11710.3 KII91648.1 - 6.1e-09 35.7 6.1 1.1e-08 34.8 4.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KII91648.1 - 4.5e-05 22.7 4.4 7e-05 22.0 3.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KII91648.1 - 0.00098 18.8 1.5 0.0019 17.8 0.0 2.2 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term AAA_5 PF07728.9 KII91649.1 - 1.7e-69 231.9 0.0 6.6e-29 100.4 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 KII91649.1 - 2.5e-05 24.4 0.0 5.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.1 KII91649.1 - 0.025 14.5 0.8 0.54 10.2 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain CbbQ_C PF08406.5 KII91649.1 - 0.049 13.6 0.1 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.1 KII91649.1 - 0.089 12.9 0.1 0.56 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KII91649.1 - 0.12 12.6 0.0 0.67 10.1 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) vWA-TerF-like PF10138.4 KII91649.1 - 0.12 12.1 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 vWA found in TerF C terminus AAA_32 PF13654.1 KII91649.1 - 0.16 10.6 0.6 5.8 5.4 0.3 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_C39_2 PF13529.1 KII91649.1 - 0.25 11.6 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family WD40 PF00400.27 KII91650.1 - 9.2e-32 107.7 14.5 1.8e-10 40.2 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KII91650.1 - 2.3e-26 91.6 6.7 4.5e-26 90.6 4.6 1.5 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KII91650.1 - 0.0057 16.3 0.0 0.031 13.9 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF2259 PF10016.4 KII91650.1 - 0.061 13.0 1.2 0.085 12.5 0.0 1.7 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) Coatomer_WDAD PF04053.9 KII91650.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Vps26 PF03643.10 KII91652.1 - 2e-128 426.9 2.4 2.3e-128 426.7 1.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KII91652.1 - 0.013 15.3 0.4 1.6 8.5 0.1 3.3 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Sds3 PF08598.6 KII91653.1 - 5.7e-18 65.1 0.0 7.7e-17 61.5 0.0 2.7 3 0 0 3 3 3 1 Sds3-like Plus-3 PF03126.13 KII91654.1 - 5.6e-22 77.8 0.0 3.4e-21 75.3 0.0 2.4 2 1 1 3 3 3 1 Plus-3 domain F-box PF00646.28 KII91655.1 - 8.4e-07 28.4 1.8 0.00041 19.9 0.0 3.7 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 KII91655.1 - 6.1e-06 25.8 0.2 3.9e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like DUF3760 PF12586.3 KII91655.1 - 0.12 12.2 0.5 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) LRR_adjacent PF08191.6 KII91656.1 - 0.11 12.2 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 LRR adjacent DUF2013 PF09431.5 KII91657.1 - 1.4e-46 157.7 0.2 2.6e-46 156.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Abhydrolase_3 PF07859.8 KII91658.1 - 9.6e-16 57.9 0.6 1.2e-14 54.3 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII91658.1 - 5.5e-07 29.4 0.1 7.4e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII91658.1 - 2.9e-06 26.2 0.2 6.2e-06 25.2 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KII91658.1 - 9.2e-06 25.7 1.1 1.3e-05 25.2 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KII91658.1 - 0.0035 16.0 0.0 0.005 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KII91658.1 - 0.03 13.5 0.0 0.21 10.7 0.0 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Pkinase PF00069.20 KII91659.1 - 1.8e-72 243.6 0.0 2.3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91659.1 - 1.1e-33 116.4 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII91659.1 - 1.5e-05 24.1 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII91659.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII91659.1 - 0.0033 17.1 0.0 0.024 14.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KII91659.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Gti1_Pac2 PF09729.4 KII91662.1 - 2.9e-41 141.1 0.6 3.3e-40 137.6 0.4 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family MIP PF00230.15 KII91664.1 - 4.5e-54 183.3 5.8 5.3e-54 183.0 4.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KII91664.1 - 0.14 11.8 5.2 0.21 11.2 1.9 2.6 2 1 1 3 3 3 0 PAP2 superfamily TauE PF01925.14 KII91664.1 - 2.6 7.4 15.1 2.3 7.6 4.0 2.4 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE NAD_binding_6 PF08030.7 KII91666.1 - 3.2e-36 124.5 0.0 5.8e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KII91666.1 - 2.3e-23 82.0 0.0 5.9e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KII91666.1 - 1.3e-14 54.3 6.9 1.3e-14 54.3 4.8 2.5 1 1 2 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KII91666.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4131 PF13567.1 KII91666.1 - 0.84 9.0 3.5 0.81 9.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ATP_synt_I PF03899.10 KII91666.1 - 8.8 6.5 10.9 6.1 7.0 0.9 3.4 4 0 0 4 4 4 0 ATP synthase I chain Glyco_hydro_28 PF00295.12 KII91667.1 - 8.3e-40 136.7 0.6 2.5e-39 135.1 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Methyltransf_3 PF01596.12 KII91669.1 - 8e-43 145.8 0.0 1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KII91669.1 - 3.8e-17 63.0 0.0 7.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII91669.1 - 1.7e-09 38.2 0.0 3.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII91669.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KII91669.1 - 1.6e-07 31.1 0.1 2.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KII91669.1 - 1.1e-05 25.4 0.1 4.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KII91669.1 - 0.0071 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.7 KII91669.1 - 0.063 13.7 0.0 0.57 10.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 KII91671.1 - 5.2e-44 149.7 0.0 6.6e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KII91671.1 - 1.9e-16 60.7 0.0 3.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII91671.1 - 2.8e-10 40.7 0.1 5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII91671.1 - 1.9e-08 34.0 0.0 2.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII91671.1 - 1e-07 32.0 0.1 2.6e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KII91671.1 - 9.9e-07 28.4 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KII91671.1 - 0.00046 19.3 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KII91671.1 - 0.013 14.8 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GCD14 PF08704.5 KII91671.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.7 KII91671.1 - 0.023 15.1 0.1 0.22 12.0 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_4 PF08386.5 KII91672.1 - 1.6e-19 69.6 0.1 3.8e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KII91672.1 - 3.5e-12 46.3 0.0 4e-11 42.9 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII91672.1 - 3.2e-11 43.5 0.0 1.7e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family VIT1 PF01988.14 KII91673.1 - 4.9e-68 228.8 8.1 5.6e-68 228.5 5.6 1.0 1 0 0 1 1 1 1 VIT family ThiF PF00899.16 KII91674.1 - 4.9e-36 123.5 0.3 8.2e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KII91674.1 - 2e-05 23.7 0.1 4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KII91674.1 - 0.00058 20.0 0.1 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 KII91674.1 - 0.0013 17.6 0.3 0.0027 16.6 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KII91674.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KII91674.1 - 0.0056 16.1 0.1 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KII91674.1 - 0.015 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 KII91674.1 - 0.03 13.3 0.3 0.044 12.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DUF3824 PF12868.2 KII91674.1 - 0.046 14.6 0.3 0.074 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) 3Beta_HSD PF01073.14 KII91674.1 - 0.08 11.6 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KII91674.1 - 0.091 12.8 0.8 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KII91674.1 - 0.099 12.6 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain MTS PF05175.9 KII91674.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Yip1 PF04893.12 KII91676.1 - 2.9e-07 30.1 23.0 4.4e-07 29.5 16.0 1.4 1 0 0 1 1 1 1 Yip1 domain Peroxidase_2 PF01328.12 KII91677.1 - 5.3e-21 74.6 0.3 2.4e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Peroxidase, family 2 ADH_N PF08240.7 KII91678.1 - 1.7e-26 92.0 0.6 3.3e-26 91.1 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII91678.1 - 1.2e-23 83.0 0.2 2.4e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KII91678.1 - 3.9e-05 23.1 0.5 0.00015 21.3 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KII91678.1 - 0.0035 18.2 0.0 0.006 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KII91678.1 - 0.015 15.3 0.4 0.03 14.3 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KII91678.1 - 0.022 14.8 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidase PF01425.16 KII91679.1 - 4.1e-75 253.3 0.1 1.6e-73 248.0 0.1 2.0 1 1 0 1 1 1 1 Amidase EBV-NA1 PF02905.9 KII91680.1 - 0.88 9.0 3.0 0.69 9.3 0.1 1.9 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain zf-C3HC4_3 PF13920.1 KII91681.1 - 3.8e-11 42.4 15.4 2.3e-07 30.3 4.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII91681.1 - 1.7e-10 40.7 17.6 5.1e-05 23.2 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KII91681.1 - 2e-10 40.3 0.9 5.5e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 Rtf2 RING-finger zf-RING_2 PF13639.1 KII91681.1 - 4.2e-06 26.4 15.4 0.0031 17.3 5.4 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KII91681.1 - 1.4e-05 24.7 19.6 1.9e-05 24.2 5.3 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII91681.1 - 3e-05 23.5 17.8 0.011 15.3 5.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII91681.1 - 0.016 15.0 15.3 0.43 10.4 0.7 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII91681.1 - 0.05 13.3 9.7 0.76 9.5 4.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DUF4207 PF13904.1 KII91681.1 - 0.07 12.4 1.5 0.14 11.5 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) zf-rbx1 PF12678.2 KII91681.1 - 0.21 11.7 8.0 0.1 12.6 1.9 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger FYVE PF01363.16 KII91681.1 - 0.25 11.2 12.1 0.15 12.0 2.2 2.7 2 1 0 2 2 2 0 FYVE zinc finger Elf1 PF05129.8 KII91681.1 - 0.33 10.6 5.4 0.078 12.6 0.5 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like IATP PF04568.7 KII91681.1 - 0.71 9.9 6.2 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Siva PF05458.7 KII91681.1 - 1 8.8 10.0 0.22 11.0 2.7 2.2 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DZR PF12773.2 KII91681.1 - 1.8 8.4 14.2 12 5.7 5.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon MRP-L20 PF12824.2 KII91681.1 - 7.6 6.4 7.1 23 4.9 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Glyco_hydro_31 PF01055.21 KII91682.1 - 1.9e-88 297.2 2.3 2.4e-88 296.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KII91682.1 - 3.1e-05 23.7 0.1 9.3e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like Thaumatin PF00314.12 KII91684.1 - 2.8e-58 196.9 5.2 3.2e-58 196.7 3.6 1.0 1 0 0 1 1 1 1 Thaumatin family SYF2 PF08231.7 KII91685.1 - 9.5e-47 158.9 11.3 9.5e-47 158.9 7.8 2.4 2 1 0 2 2 2 1 SYF2 splicing factor Mei4 PF13971.1 KII91685.1 - 0.2 10.6 3.4 0.27 10.1 2.3 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 5_nucleotid PF05761.9 KII91685.1 - 8.9 4.6 7.9 28 3.0 5.5 2.0 1 1 0 1 1 1 0 5' nucleotidase family Pkinase PF00069.20 KII91686.1 - 3.9e-21 75.3 0.0 2.4e-20 72.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91686.1 - 4.8e-10 38.9 0.0 4e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII91686.1 - 0.077 12.3 0.7 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pyr_redox_2 PF07992.9 KII91687.1 - 2.3e-26 92.9 0.0 8.7e-26 91.0 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII91687.1 - 2.8e-12 46.8 0.1 2.2e-09 37.6 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII91687.1 - 3.9e-05 23.8 0.0 0.0029 17.6 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CytB6-F_Fe-S PF08802.5 KII91687.1 - 0.053 13.5 0.1 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Pinin_SDK_N PF04697.8 KII91688.1 - 0.045 13.7 0.1 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region Phage_GPD PF05954.6 KII91688.1 - 0.05 12.8 1.8 0.065 12.4 0.8 1.5 1 1 0 1 1 1 0 Phage late control gene D protein (GPD) MFS_1 PF07690.11 KII91689.1 - 1.3e-34 119.4 34.5 2e-34 118.8 23.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII91690.1 - 1.9e-81 273.9 29.0 2.4e-81 273.6 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII91690.1 - 7.4e-21 74.2 75.5 2.8e-15 55.8 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.4 KII91691.1 - 5.5e-10 39.5 5.1 5.5e-10 39.5 3.5 2.3 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.6 KII91691.1 - 9.4 4.1 8.8 8.7 4.3 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apc1 PF12859.2 KII91692.1 - 1.7e-09 37.8 0.0 5.7e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KII91692.1 - 0.00014 21.9 14.0 0.84 9.9 0.0 5.6 6 0 0 6 6 6 3 Proteasome/cyclosome repeat MCM PF00493.18 KII91693.1 - 2.7e-131 437.2 0.0 3.6e-131 436.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KII91693.1 - 5.3e-19 68.8 0.0 3e-18 66.4 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 KII91693.1 - 6e-08 32.5 0.0 1.7e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KII91693.1 - 2.8e-07 29.9 0.0 8.7e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KII91693.1 - 0.00018 21.0 0.0 0.0049 16.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KII91693.1 - 0.0012 18.3 0.1 1.4 8.4 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA PF00004.24 KII91693.1 - 0.093 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KII91693.1 - 0.2 11.6 0.0 0.59 10.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain APH PF01636.18 KII91694.1 - 0.0085 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DAO PF01266.19 KII91698.1 - 1.2e-56 192.1 1.5 2.1e-56 191.3 1.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII91698.1 - 1e-05 25.4 0.3 4e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KII91698.1 - 1.2e-05 25.2 1.9 0.035 13.9 0.0 2.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KII91698.1 - 0.00016 20.4 0.1 0.011 14.4 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 KII91698.1 - 0.001 19.4 0.3 0.0032 17.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII91698.1 - 0.0021 17.8 0.5 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 KII91698.1 - 0.0037 16.4 0.1 0.53 9.3 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.17 KII91698.1 - 0.0074 15.1 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Saccharop_dh PF03435.13 KII91698.1 - 0.071 12.0 0.2 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thi4 PF01946.12 KII91698.1 - 0.13 11.3 0.3 0.23 10.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.20 KII91699.1 - 1.3e-20 73.6 0.0 2.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KII91699.1 - 9.7e-19 66.4 14.7 7.4e-09 35.1 0.6 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 KII91699.1 - 6.1e-13 47.6 12.1 0.021 14.8 0.1 6.4 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 KII91699.1 - 1.9e-07 31.2 1.2 0.043 14.1 0.0 3.7 1 1 3 4 4 4 4 HEAT repeats Pkinase_Tyr PF07714.12 KII91699.1 - 3.6e-07 29.5 0.0 2.2e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Cohesin_HEAT PF12765.2 KII91699.1 - 0.022 14.7 6.0 0.13 12.2 0.2 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KII91699.1 - 0.038 13.8 2.6 5.7 6.7 0.2 3.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KII91699.1 - 0.11 12.8 1.6 2.4 8.5 0.1 2.8 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KII91699.1 - 6.8 7.3 14.1 0.52 10.8 0.2 4.3 5 0 0 5 5 5 0 HEAT-like repeat zf-MYND PF01753.13 KII91700.1 - 9.5e-10 38.1 11.6 2.4e-09 36.9 8.1 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KII91700.1 - 1.1 8.9 8.3 3.7 7.2 5.8 1.9 1 1 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.1 KII91700.1 - 2.3 8.1 5.6 11 5.9 4.0 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Asp_protease_2 PF13650.1 KII91701.1 - 0.0016 18.8 0.0 0.009 16.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KII91701.1 - 0.0088 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Yip1 PF04893.12 KII91702.1 - 4.7e-07 29.4 8.6 5.4e-07 29.2 5.9 1.1 1 0 0 1 1 1 1 Yip1 domain SET PF00856.23 KII91704.1 - 7.5e-13 49.0 0.0 1.4e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 KII91705.1 - 2e-09 37.1 12.2 3.5e-09 36.3 8.5 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII91705.1 - 1.3 8.9 7.4 21 5.0 5.4 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DIM PF08194.7 KII91706.1 - 0.14 12.1 0.9 0.23 11.4 0.6 1.4 1 0 0 1 1 1 0 DIM protein UcrQ PF02939.11 KII91707.1 - 5.9e-23 80.4 1.9 7.1e-23 80.2 1.3 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 KII91707.1 - 0.0067 16.5 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) MFS_1 PF07690.11 KII91708.1 - 7.1e-38 130.2 69.9 6.8e-28 97.3 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII91708.1 - 7.2e-06 24.6 9.3 7.2e-06 24.6 6.4 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein NAD_binding_4 PF07993.7 KII91709.1 - 8.6e-33 113.2 0.0 1.4e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KII91709.1 - 1.3e-29 102.8 0.0 3e-29 101.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KII91709.1 - 7.2e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII91709.1 - 1.7e-05 24.9 0.1 6.8e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding PP-binding PF00550.20 KII91709.1 - 6.5e-05 23.1 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KII91709.1 - 0.00033 20.6 0.3 0.00088 19.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII91709.1 - 0.0023 17.5 0.0 0.0071 16.0 0.0 1.8 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KII91709.1 - 0.037 12.9 0.0 0.46 9.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SNF5 PF04855.7 KII91710.1 - 1.8e-72 243.7 0.5 3.1e-72 242.9 0.4 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KII91710.1 - 0.0085 15.4 2.8 0.017 14.4 1.9 1.6 1 0 0 1 1 1 1 GATA zinc finger Elf1 PF05129.8 KII91710.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AAA_11 PF13086.1 KII91711.1 - 2.6e-59 200.6 0.0 4.9e-59 199.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KII91711.1 - 7e-57 192.0 0.0 1.2e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII91711.1 - 4.3e-12 45.6 0.1 3.5e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KII91711.1 - 1e-09 38.2 0.1 0.0094 15.4 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KII91711.1 - 4.8e-08 32.8 0.0 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KII91711.1 - 0.00027 21.0 0.0 0.0054 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII91711.1 - 0.00043 20.3 0.1 0.00098 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KII91711.1 - 0.00099 18.9 0.0 0.0073 16.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 KII91711.1 - 0.0041 17.2 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KII91711.1 - 0.0086 15.4 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 KII91711.1 - 0.012 14.6 0.0 0.98 8.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KII91711.1 - 0.013 15.6 0.0 0.052 13.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.1 KII91711.1 - 0.04 13.3 1.2 0.16 11.4 0.1 2.2 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KII91711.1 - 0.044 12.7 0.0 7.9 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase ABC_tran PF00005.22 KII91711.1 - 0.05 13.9 0.0 0.93 9.7 0.0 2.6 1 1 1 2 2 2 0 ABC transporter AAA_25 PF13481.1 KII91711.1 - 0.071 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII91712.1 - 1.1e-11 44.9 0.0 3.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 KII91712.1 - 1.3e-06 28.5 0.0 5.2e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII91712.1 - 0.00067 19.8 0.0 0.4 10.8 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA PF00004.24 KII91712.1 - 0.01 16.0 0.0 6.7 6.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KII91712.1 - 0.019 14.8 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 KII91712.1 - 0.026 13.0 0.0 0.047 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein ResIII PF04851.10 KII91712.1 - 0.086 12.6 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 KII91714.1 - 3.5e-08 33.3 6.8 3.5e-08 33.3 4.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII91714.1 - 4.1e-08 32.7 4.1 4.1e-08 32.7 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII91714.1 - 2.8e-07 30.2 5.8 2.8e-07 30.2 4.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KII91714.1 - 4.2e-07 29.5 5.8 4.2e-07 29.5 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII91714.1 - 6.1e-06 25.8 4.7 6.1e-06 25.8 3.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII91714.1 - 0.00011 21.9 4.1 0.00011 21.9 2.8 2.9 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII91714.1 - 0.00042 19.9 2.1 0.00042 19.9 1.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 KII91714.1 - 0.0013 18.4 0.1 0.0013 18.4 0.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Vps39_2 PF10367.4 KII91714.1 - 0.04 14.1 2.2 0.05 13.7 0.6 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-ribbon_3 PF13248.1 KII91714.1 - 0.71 9.1 3.6 5.7 6.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Tmemb_cc2 PF10267.4 KII91714.1 - 1.6 7.2 8.0 2.8 6.4 5.6 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-UBR PF02207.15 KII91714.1 - 7.2 6.4 9.1 2.2 8.0 0.7 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) TPT PF03151.11 KII91715.1 - 4.7e-26 91.2 14.1 8.1e-23 80.7 1.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KII91715.1 - 6.4e-11 41.7 11.6 1.3e-05 24.2 0.6 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KII91715.1 - 2e-08 34.3 27.5 7.8e-06 25.9 7.4 3.4 3 1 1 4 4 4 2 EamA-like transporter family EmrE PF13536.1 KII91715.1 - 0.00068 19.8 22.5 0.0071 16.5 2.4 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter YtpI PF14007.1 KII91715.1 - 0.87 9.5 16.2 1.7 8.6 0.1 4.2 2 2 3 5 5 5 0 YtpI-like protein HTH_AsnC-type PF13404.1 KII91716.1 - 0.063 12.8 2.4 0.54 9.8 0.1 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Peptidase_S41 PF03572.13 KII91717.1 - 1.4e-05 24.5 0.0 6.1e-05 22.4 0.0 2.1 2 1 0 2 2 2 1 Peptidase family S41 Abhydrolase_6 PF12697.2 KII91718.1 - 2.6e-20 73.2 0.9 5.2e-20 72.3 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII91718.1 - 7.6e-05 22.5 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII91718.1 - 7.8e-05 22.3 0.0 0.00015 21.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII91718.1 - 0.0019 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 KII91718.1 - 0.03 12.5 0.0 0.21 9.8 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 KII91718.1 - 0.038 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1308 PF07000.6 KII91720.1 - 1.1e-26 93.3 0.0 5.1e-26 91.1 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1308) Abhydrolase_6 PF12697.2 KII91721.1 - 6.4e-10 39.2 1.0 6.9e-10 39.1 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII91721.1 - 0.00021 20.9 0.1 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII91721.1 - 0.013 15.2 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 KII91721.1 - 0.11 11.9 0.2 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative esterase SSF PF00474.12 KII91723.1 - 8.7e-21 74.0 31.2 1.5e-20 73.2 21.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DIOX_N PF14226.1 KII91724.1 - 2.5e-12 47.3 0.0 5.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII91724.1 - 3.4e-10 40.1 0.0 1.2e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SET PF00856.23 KII91726.1 - 6.3e-27 94.8 0.1 1.9e-26 93.2 0.1 1.8 1 1 0 1 1 1 1 SET domain N-SET PF11764.3 KII91726.1 - 2.1e-12 47.2 1.6 3e-11 43.4 0.2 2.3 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N O-FucT PF10250.4 KII91727.1 - 1e-12 47.8 0.0 3.7e-12 46.0 0.0 1.8 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.2 KII91728.1 - 0.00053 19.6 4.6 0.0026 17.4 1.4 2.8 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KII91728.1 - 0.02 14.6 1.9 0.058 13.1 0.7 2.3 2 1 0 2 2 2 0 Leucine rich repeat Abhydrolase_6 PF12697.2 KII91729.1 - 1.5e-17 64.2 0.0 2.1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII91729.1 - 5e-06 26.2 0.1 8.8e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII91729.1 - 1.1e-05 25.2 0.1 1.9e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family O-FucT PF10250.4 KII91730.1 - 1.4e-08 34.2 0.0 2.6e-06 26.7 0.0 2.4 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase HATPase_c_3 PF13589.1 KII91731.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldedh PF00171.17 KII91733.1 - 5.7e-128 427.1 0.0 6.8e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 KII91733.1 - 0.078 12.6 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated LuxC PF05893.9 KII91733.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) WD40 PF00400.27 KII91734.1 - 7e-14 51.0 3.7 0.0035 17.1 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4394 PF14339.1 KII91734.1 - 0.00017 20.9 0.0 0.00054 19.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4394) SGL PF08450.7 KII91734.1 - 0.0079 15.5 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Ribonuc_2-5A PF06479.7 KII91735.1 - 1.9e-44 150.5 0.1 3.1e-44 149.9 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KII91735.1 - 5.7e-39 133.8 0.0 7.7e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91735.1 - 7.8e-19 67.7 0.0 1.8e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KII91735.1 - 2.3e-06 27.2 0.1 4.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 KII91735.1 - 0.0023 17.3 0.0 0.024 14.1 0.0 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 KII91735.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII91735.1 - 0.018 14.7 0.2 0.44 10.2 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Thr_synth_N PF14821.1 KII91736.1 - 2.8e-26 91.3 0.0 7.4e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KII91736.1 - 6.7e-18 64.9 0.0 3e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_2b PF00587.20 KII91737.1 - 2.2e-35 121.7 0.1 4.7e-35 120.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KII91737.1 - 2.9e-20 72.3 5.4 2.9e-20 72.3 3.8 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain ATPase_gene1 PF09527.5 KII91738.1 - 0.23 11.2 0.2 0.23 11.2 0.2 1.8 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) WD40 PF00400.27 KII91739.1 - 4e-54 178.6 19.9 3.7e-11 42.4 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KII91739.1 - 2.7e-08 33.3 1.0 5.5e-08 32.4 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII91739.1 - 2.6e-07 30.1 0.3 5.8e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KII91739.1 - 4.1e-06 25.2 4.3 0.12 10.5 0.0 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KII91739.1 - 0.00012 20.9 0.3 1.7 7.2 0.0 4.5 2 1 2 5 5 5 1 Nup133 N terminal like FlaG PF03646.10 KII91739.1 - 0.29 11.2 0.0 18 5.4 0.0 3.0 2 1 1 3 3 3 0 FlaG protein Glyco_hyd_65N_2 PF14498.1 KII91742.1 - 2.4e-40 138.7 0.3 4.2e-40 137.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STAG PF08514.6 KII91743.1 - 1.7e-28 98.7 0.1 8e-28 96.5 0.1 2.3 1 1 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KII91743.1 - 5.4e-10 39.4 0.0 4e-05 23.8 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KII91743.1 - 4.2e-06 26.3 0.1 5.8 7.2 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat DUF4318 PF14201.1 KII91743.1 - 0.21 11.4 0.1 0.45 10.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) GAS PF13851.1 KII91744.1 - 0.00077 18.7 0.2 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KII91744.1 - 0.0018 18.0 4.5 0.28 10.9 0.3 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KII91744.1 - 0.0091 15.6 5.1 0.018 14.6 3.5 1.4 1 0 0 1 1 1 1 IncA protein TPR_MLP1_2 PF07926.7 KII91744.1 - 0.017 14.8 3.7 0.038 13.7 2.5 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cytochrom_C_2 PF01322.15 KII91744.1 - 0.033 14.7 0.3 0.29 11.6 0.0 2.2 1 1 1 2 2 2 0 Cytochrome C' DUF2935 PF11155.3 KII91744.1 - 0.046 13.8 1.3 4.5 7.3 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Helicase_IV_N PF12462.3 KII91744.1 - 0.063 12.9 2.9 0.14 11.7 2.0 1.6 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Nup54 PF13874.1 KII91744.1 - 0.096 12.3 3.6 0.19 11.3 2.5 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4201 PF13870.1 KII91744.1 - 0.12 11.7 4.2 0.56 9.6 2.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) APH PF01636.18 KII91744.1 - 0.17 11.5 1.6 0.3 10.7 1.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GvpK PF05121.7 KII91744.1 - 0.19 11.5 5.9 0.21 11.4 1.0 2.2 1 1 1 2 2 2 0 Gas vesicle protein K DUF3053 PF11254.3 KII91744.1 - 0.43 9.7 2.7 0.61 9.2 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) APG6 PF04111.7 KII91744.1 - 0.58 9.1 4.8 1.3 7.9 3.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 KII91744.1 - 0.6 10.1 4.9 3.3 7.7 0.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor MAP65_ASE1 PF03999.7 KII91744.1 - 0.61 8.6 8.4 0.86 8.1 5.3 1.6 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TBPIP PF07106.8 KII91744.1 - 0.71 9.3 3.5 12 5.4 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 KII91744.1 - 1.1 9.6 3.7 20 5.5 2.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 KII91744.1 - 1.3 8.4 4.6 2.2 7.6 0.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 KII91744.1 - 1.7 8.4 5.5 17 5.3 0.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KII91744.1 - 5.5 6.5 6.8 12 5.4 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator Serglycin PF04360.7 KII91745.1 - 0.0044 16.7 0.3 0.0099 15.6 0.2 1.6 1 0 0 1 1 1 1 Serglycin DUF3292 PF11696.3 KII91746.1 - 1e-71 241.7 0.0 2.3e-71 240.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) IncA PF04156.9 KII91747.1 - 0.016 14.8 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4482 PF14818.1 KII91747.1 - 0.18 12.4 3.9 0.37 11.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) ERM PF00769.14 KII91747.1 - 0.28 10.6 5.1 0.57 9.6 0.9 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Pkinase PF00069.20 KII91748.1 - 1.3e-35 122.8 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91748.1 - 3.3e-09 36.2 0.0 5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII91748.1 - 1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KII91748.1 - 0.0022 16.8 0.1 0.0046 15.8 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KII91748.1 - 0.0037 17.0 0.1 0.019 14.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family NUT_C PF12882.2 KII91748.1 - 0.14 11.7 0.3 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 NUT protein C terminal ATP-synt_C PF00137.16 KII91749.1 - 0.59 10.0 4.6 0.26 11.2 0.4 2.5 2 1 0 2 2 2 0 ATP synthase subunit C Urm1 PF09138.6 KII91750.1 - 2.8e-33 113.9 0.1 6.9e-31 106.2 0.0 2.0 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KII91750.1 - 7.1e-06 26.3 0.0 1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 ThiS family HIG_1_N PF04588.8 KII91752.1 - 7.3e-12 44.8 0.6 1.4e-11 43.8 0.4 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PaaSYMP PF14738.1 KII91752.1 - 0.27 10.9 8.1 0.19 11.4 4.2 1.7 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 CobT PF06213.7 KII91753.1 - 0.02 14.0 1.7 0.032 13.3 1.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1125 PF06563.6 KII91753.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) 2-Hacid_dh_C PF02826.14 KII91754.1 - 1.4e-40 138.3 0.0 1.9e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII91754.1 - 2.2e-16 59.5 0.0 2.6e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KII91754.1 - 3.6e-06 26.8 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Complex1_LYR_1 PF13232.1 KII91755.1 - 7.3e-14 51.7 0.2 1e-13 51.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KII91755.1 - 1.3e-11 44.1 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DHH PF01368.15 KII91756.1 - 2.7e-10 40.0 0.2 7.3e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 DHH family DHHA2 PF02833.9 KII91756.1 - 5.4e-08 33.0 0.0 1.5e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 DHHA2 domain FMN_dh PF01070.13 KII91757.1 - 1.1e-104 350.1 0.0 1.3e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KII91757.1 - 0.00028 19.8 0.6 0.00046 19.1 0.4 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KII91757.1 - 0.00044 19.4 1.5 0.00064 18.9 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KII91757.1 - 0.00048 19.1 0.2 0.00071 18.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KII91757.1 - 0.00092 18.2 0.2 0.0034 16.3 0.0 1.8 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KII91757.1 - 0.012 14.8 0.2 0.13 11.5 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 KII91757.1 - 0.029 13.4 0.5 1.6 7.7 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Ribosomal_S30 PF04758.9 KII91758.1 - 7.6e-30 102.4 4.8 8.6e-30 102.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pterin_bind PF00809.17 KII91759.1 - 2.9e-53 180.3 0.0 4.4e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KII91759.1 - 2.4e-33 114.5 0.0 2e-32 111.5 0.0 2.3 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 KII91759.1 - 1.4e-28 99.3 0.3 1.1e-13 51.2 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase FR47 PF08445.5 KII91760.1 - 1.6e-05 24.5 0.1 4.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 KII91760.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII91760.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_14 PF13428.1 KII91761.1 - 4.1e-09 36.2 2.8 0.031 14.8 0.0 5.3 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII91761.1 - 4.5e-09 36.5 0.8 0.0003 21.0 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII91761.1 - 7.5e-08 32.8 0.7 0.0079 16.8 0.0 5.0 4 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII91761.1 - 1.7e-06 27.5 0.0 0.0023 17.5 0.0 3.1 1 1 3 4 4 4 3 TPR repeat TPR_2 PF07719.12 KII91761.1 - 8.5e-06 25.3 0.0 0.036 13.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII91761.1 - 8.2e-05 22.1 0.0 0.12 12.2 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII91761.1 - 0.0007 19.8 0.4 0.72 10.4 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KII91761.1 - 0.0026 17.2 0.2 0.048 13.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Imm43 PF15602.1 KII91761.1 - 0.0089 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 43 TPR_9 PF13371.1 KII91761.1 - 0.011 15.5 1.3 1.6 8.6 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KII91761.1 - 0.069 12.9 0.6 9 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 KII91762.1 - 1.4e-21 76.8 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII91762.1 - 1.8e-06 28.4 0.0 4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII91762.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII91762.1 - 0.0019 17.8 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RPA_C PF08784.6 KII91762.1 - 0.0068 16.8 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 Replication protein A C terminal MTS PF05175.9 KII91762.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KII91762.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rrf2 PF02082.15 KII91762.1 - 0.074 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.7 KII91762.1 - 0.15 11.7 0.4 6.2 6.5 0.1 2.4 2 0 0 2 2 2 0 HTH domain Cytochrome-c551 PF10643.4 KII91765.1 - 0.079 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Myb_DNA-binding PF00249.26 KII91765.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain DUF605 PF04652.11 KII91765.1 - 0.4 10.0 15.7 0.69 9.2 10.8 1.4 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 KII91766.1 - 1e-07 31.1 0.0 1.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91766.1 - 1.6e-05 24.7 8.8 2.8e-05 23.9 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP1_OBG PF01018.17 KII91768.1 - 3.8e-33 114.3 5.0 4.4e-22 78.3 1.8 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KII91768.1 - 4.4e-17 62.1 0.0 8.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII91768.1 - 0.00047 19.4 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 KII91768.1 - 0.00096 18.4 0.1 0.78 8.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KII91768.1 - 0.0012 19.2 0.2 0.78 10.2 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KII91768.1 - 0.0015 18.0 0.0 0.012 15.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KII91768.1 - 0.0018 18.1 0.0 0.025 14.4 0.0 2.6 1 1 0 1 1 1 1 Dynamin family cobW PF02492.14 KII91768.1 - 0.0067 15.8 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KII91768.1 - 0.015 15.6 0.1 0.048 13.9 0.1 1.8 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 KII91768.1 - 0.64 8.7 4.0 0.37 9.5 0.0 2.3 3 0 0 3 3 3 0 ArgK protein AAA_17 PF13207.1 KII91768.1 - 1.2 9.9 5.0 2.3 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain FAM110_C PF14160.1 KII91769.1 - 0.11 13.4 0.7 0.11 13.4 0.5 2.0 2 0 0 2 2 2 0 Centrosome-associated C terminus Gti1_Pac2 PF09729.4 KII91770.1 - 1.3e-37 129.2 0.0 1.9e-31 109.2 0.0 2.1 2 0 0 2 2 2 2 Gti1/Pac2 family adh_short PF00106.20 KII91772.1 - 2e-13 50.5 0.6 3.3e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91772.1 - 3.4e-05 23.5 0.3 7.2e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KII91772.1 - 0.015 15.3 0.2 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KII91772.1 - 0.029 14.1 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-MYND PF01753.13 KII91773.1 - 1.8e-10 40.4 16.6 2.8e-10 39.8 11.5 1.3 1 0 0 1 1 1 1 MYND finger CLN3 PF02487.12 KII91774.1 - 1.4e-64 218.4 6.6 5.8e-58 196.5 0.3 2.0 1 1 1 2 2 2 2 CLN3 protein DEAD PF00270.24 KII91775.1 - 2.5e-44 150.7 0.0 4.8e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KII91775.1 - 4e-25 87.1 0.2 7.7e-25 86.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KII91775.1 - 2.7e-21 75.2 0.0 6.8e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TLP-20 PF06088.6 KII91775.1 - 0.84 9.2 9.9 0.055 13.1 1.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) F-box-like PF12937.2 KII91776.1 - 2.8e-05 23.7 3.9 0.00016 21.2 2.7 2.4 1 1 0 1 1 1 1 F-box-like Syndecan PF01034.15 KII91777.1 - 0.15 11.7 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Syndecan domain BAH PF01426.13 KII91778.1 - 3.9e-10 39.5 0.4 6.3e-10 38.8 0.3 1.3 1 0 0 1 1 1 1 BAH domain DUF1610 PF07754.6 KII91778.1 - 0.022 14.8 2.5 0.023 14.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) AT_hook PF02178.14 KII91778.1 - 0.2 11.4 5.0 0.62 9.9 3.5 1.9 1 0 0 1 1 1 0 AT hook motif TB2_DP1_HVA22 PF03134.14 KII91779.1 - 6.7e-26 89.8 6.8 6.7e-26 89.8 4.7 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Velvet PF11754.3 KII91780.1 - 5.7e-27 94.6 0.0 1.3e-26 93.4 0.0 1.5 1 1 0 1 1 1 1 Velvet factor Fungal_trans PF04082.13 KII91782.1 - 4.5e-18 65.0 0.0 7.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MARVEL PF01284.18 KII91783.1 - 0.061 13.1 0.2 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Membrane-associating domain BPD_transp_2 PF02653.11 KII91783.1 - 0.061 12.2 0.5 0.14 11.1 0.3 1.5 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF1275 PF06912.6 KII91783.1 - 0.085 12.0 3.8 0.071 12.2 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF3357 PF11837.3 KII91783.1 - 0.17 11.7 0.2 0.17 11.7 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) P12 PF12669.2 KII91783.1 - 0.8 9.9 3.7 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family BTB PF00651.26 KII91784.1 - 0.00032 20.6 0.0 0.00061 19.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DNA_ligase_ZBD PF03119.11 KII91784.1 - 0.085 12.5 1.0 8 6.2 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Glucan_synthase PF02364.10 KII91785.1 - 0 1394.2 0.0 0 1393.7 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KII91785.1 - 2.2e-39 134.0 0.6 8.8e-39 132.0 0.0 2.3 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Thaumatin PF00314.12 KII91787.1 - 1.6e-61 207.4 9.4 1.8e-61 207.3 6.5 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.16 KII91787.1 - 0.033 13.7 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat F-box-like PF12937.2 KII91788.1 - 3.6e-09 36.1 0.5 2e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII91788.1 - 0.00014 21.4 0.3 0.0011 18.5 0.0 2.7 2 0 0 2 2 2 1 F-box domain Smg4_UPF3 PF03467.10 KII91789.1 - 1.8e-21 76.8 0.1 2.2e-21 76.6 0.1 1.0 1 0 0 1 1 1 1 Smg-4/UPF3 family HLH PF00010.21 KII91790.1 - 1.8e-10 40.3 0.0 3.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PTH2 PF01981.11 KII91790.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 GPI-anchored PF10342.4 KII91792.1 - 0.0073 16.7 0.0 0.0085 16.5 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MoCF_biosynth PF00994.19 KII91793.1 - 9.9e-33 112.5 0.0 2e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain Peptidase_S24 PF00717.18 KII91794.1 - 6e-08 32.2 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Glyco_hydro_30 PF02055.11 KII91795.1 - 1.8e-30 105.6 2.8 2.9e-30 104.9 1.9 1.3 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RE_MjaI PF09568.5 KII91796.1 - 0.00033 20.2 0.1 0.35 10.3 0.1 2.9 3 0 0 3 3 3 2 MjaI restriction endonuclease SAP PF02037.22 KII91798.1 - 6.9e-06 25.4 0.3 1.3e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.8 KII91798.1 - 0.025 13.6 0.0 0.056 12.4 0.0 1.5 1 0 0 1 1 1 0 LETM1-like protein F-box-like PF12937.2 KII91799.1 - 0.015 15.0 0.2 0.042 13.5 0.1 1.9 1 0 0 1 1 1 0 F-box-like Gti1_Pac2 PF09729.4 KII91801.1 - 5.2e-39 133.8 0.9 1.3e-37 129.2 0.6 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family CMD PF02627.15 KII91802.1 - 0.0038 17.0 0.1 0.0079 16.0 0.1 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CUE PF02845.11 KII91802.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 CUE domain adh_short PF00106.20 KII91803.1 - 2.2e-12 47.1 0.5 3.3e-12 46.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91803.1 - 2.6e-05 23.9 0.2 4.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KII91803.1 - 0.01 15.9 0.2 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KII91803.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-MYND PF01753.13 KII91804.1 - 2e-11 43.5 17.4 3.2e-11 42.8 12.0 1.3 1 0 0 1 1 1 1 MYND finger GIY-YIG PF01541.19 KII91805.1 - 1.9e-05 24.9 0.0 3.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING-like PF08746.6 KII91805.1 - 0.037 14.0 0.8 0.037 14.0 0.5 2.1 2 0 0 2 2 2 0 RING-like domain PDE6_gamma PF04868.7 KII91805.1 - 2.2 8.2 7.6 1.3 8.8 0.2 3.5 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit DUF1752 PF08550.5 KII91806.1 - 8.9e-08 31.5 9.5 1.6e-07 30.7 6.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) cobW PF02492.14 KII91807.1 - 2.6e-40 137.7 0.0 3.3e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KII91807.1 - 7.4e-06 25.5 0.0 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KII91807.1 - 0.0046 16.4 0.3 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KII91807.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KII91807.1 - 0.055 12.8 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KII91807.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KII91807.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-C2H2 PF00096.21 KII91809.1 - 3.1e-10 39.7 15.3 8.2e-06 25.8 3.8 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII91809.1 - 2e-08 34.1 11.2 6.4e-07 29.3 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII91809.1 - 4.9e-07 29.6 14.0 0.0028 17.8 1.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII91809.1 - 0.0019 18.2 4.0 0.073 13.2 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII91809.1 - 0.0029 17.7 0.9 0.0029 17.7 0.6 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KII91809.1 - 0.013 15.4 2.1 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 KII91809.1 - 0.03 13.9 10.1 0.28 10.8 2.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-HYPF PF07503.7 KII91809.1 - 0.094 12.1 3.2 0.75 9.2 0.6 2.3 2 0 0 2 2 2 0 HypF finger zinc_ribbon_5 PF13719.1 KII91809.1 - 0.18 11.3 1.8 4.3 7.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 KII91809.1 - 0.18 11.9 5.4 0.51 10.5 3.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KII91809.1 - 0.27 11.2 4.3 0.6 10.0 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 KII91809.1 - 0.32 10.7 2.2 5.1 6.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 KII91809.1 - 0.72 9.9 4.5 1.6 8.9 0.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DM PF00751.13 KII91809.1 - 6.8 6.3 7.9 26 4.4 5.5 1.9 1 1 0 1 1 1 0 DM DNA binding domain Toxin_7 PF05980.7 KII91810.1 - 0.0012 18.8 3.8 0.0029 17.6 2.7 1.6 1 1 0 1 1 1 1 Toxin 7 Toxin_12 PF07740.7 KII91810.1 - 0.011 16.1 1.7 0.032 14.6 1.2 1.9 1 1 0 1 1 1 0 Ion channel inhibitory toxin DUF3648 PF12364.3 KII91810.1 - 0.39 10.6 3.7 0.48 10.4 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) tRNA-synt_2b PF00587.20 KII91811.1 - 2.1e-45 154.3 0.0 4.2e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KII91811.1 - 1.8e-19 69.4 0.1 3.6e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KII91811.1 - 1.9e-15 56.4 0.0 3.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KII91811.1 - 1.4e-12 47.3 0.0 2.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CSTF2_hinge PF14327.1 KII91812.1 - 1.2e-23 82.9 2.6 1.2e-23 82.9 1.8 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KII91812.1 - 8.3e-22 76.6 0.0 1.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII91812.1 - 2.1e-14 53.2 0.0 3.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KII91812.1 - 4.8e-11 41.7 4.2 4.8e-11 41.7 2.9 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KII91812.1 - 3.3e-07 30.0 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 KII91813.1 - 4.1e-09 36.0 1.1 7.4e-09 35.2 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII91813.1 - 0.0092 15.6 1.0 1.4 8.6 0.2 2.5 2 0 0 2 2 2 2 F-box domain GLTP PF08718.6 KII91813.1 - 0.064 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) BTB PF00651.26 KII91815.1 - 1.5e-07 31.3 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII91816.1 - 3.5e-07 30.1 0.0 7.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Toxin_7 PF05980.7 KII91817.1 - 0.0033 17.4 3.5 0.0056 16.6 2.4 1.4 1 0 0 1 1 1 1 Toxin 7 Toxin_12 PF07740.7 KII91817.1 - 0.12 12.8 2.4 0.19 12.2 1.7 1.4 1 0 0 1 1 1 0 Ion channel inhibitory toxin Tachystatin_A PF11406.3 KII91817.1 - 0.15 11.9 4.5 0.26 11.1 3.1 1.4 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A F-box-like PF12937.2 KII91818.1 - 7.5e-08 31.9 1.5 2.1e-07 30.5 1.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KII91818.1 - 0.19 11.4 3.1 2.6 7.8 0.2 2.5 2 0 0 2 2 2 0 F-box domain HSP20 PF00011.16 KII91819.1 - 1e-15 57.4 0.0 1.2e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family COesterase PF00135.23 KII91820.1 - 5.2e-98 329.0 1.0 1.9e-97 327.2 0.7 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII91820.1 - 5.3e-12 45.7 0.1 2.3e-11 43.6 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KII91820.1 - 0.0088 15.4 0.4 0.028 13.8 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KII91820.1 - 0.017 14.3 0.1 0.033 13.3 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DIM PF08194.7 KII91820.1 - 0.12 12.3 2.2 6.4 6.8 0.0 2.8 3 0 0 3 3 3 0 DIM protein DUF2424 PF10340.4 KII91820.1 - 0.29 9.7 0.1 2.3 6.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 KII91821.1 - 4.3e-11 42.1 0.0 8.1e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91821.1 - 9.7e-05 22.2 13.1 0.0002 21.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TBCC PF07986.7 KII91822.1 - 1.8e-25 88.6 0.1 3.2e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF3618 PF12277.3 KII91822.1 - 0.097 12.7 5.4 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Cob_adeno_trans PF01923.13 KII91822.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Mitovir_RNA_pol PF05919.6 KII91823.1 - 4.5 6.0 0.0 8 5.2 0.0 1.3 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase zf-rbx1 PF12678.2 KII91825.1 - 2.4e-34 117.2 13.5 3e-34 116.9 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KII91825.1 - 2.6e-16 59.2 9.5 3.4e-16 58.8 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KII91825.1 - 1.7e-06 27.7 13.1 8.6e-06 25.4 9.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII91825.1 - 0.001 18.6 11.8 0.02 14.5 8.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII91825.1 - 0.0024 17.8 3.3 0.0024 17.8 2.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII91825.1 - 0.0042 16.7 10.1 0.43 10.3 7.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KII91825.1 - 0.18 11.7 9.3 0.79 9.7 6.6 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 KII91825.1 - 0.69 10.0 10.0 37 4.5 6.7 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KII91825.1 - 0.98 9.4 9.7 3.1 7.8 6.7 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 KII91825.1 - 1 9.1 7.1 1.2 8.9 1.6 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 KII91825.1 - 1.1 9.0 10.8 6.8 6.4 7.5 2.2 1 1 0 1 1 1 0 zinc-RING finger domain CRC_subunit PF08624.5 KII91827.1 - 5.5e-38 130.0 0.0 8.4e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Neisseria_TspB PF05616.8 KII91827.1 - 2.9 6.1 7.0 4.4 5.5 4.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CobT PF06213.7 KII91828.1 - 0.12 11.4 9.7 0.012 14.7 1.1 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 KII91828.1 - 1.1 7.1 14.5 0.069 11.0 4.3 2.1 2 0 0 2 2 2 0 Nop14-like family TLP-20 PF06088.6 KII91828.1 - 4.6 6.8 11.7 0.56 9.8 2.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 KII91828.1 - 6.6 6.2 17.5 12 5.4 0.1 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region RRN9 PF10680.4 KII91828.1 - 7.7 6.3 10.9 0.83 9.4 0.7 2.8 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor Abhydrolase_2 PF02230.11 KII91829.1 - 2.2e-10 40.3 0.0 1.1e-08 34.7 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KII91829.1 - 2.8e-06 27.4 0.1 5.3e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII91829.1 - 3.2e-05 23.7 0.0 7.2e-05 22.5 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KII91829.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Piwi PF02171.12 KII91830.1 - 9.4e-79 264.5 0.0 1.4e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KII91830.1 - 2.2e-19 69.1 0.1 4e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KII91830.1 - 3.2e-19 68.0 0.3 6.8e-19 66.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF3726 PF12525.3 KII91831.1 - 0.063 13.0 0.0 5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Ribonucleas_3_3 PF14622.1 KII91832.1 - 4.5e-12 46.0 0.0 7.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KII91832.1 - 5.9e-12 46.0 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Tetraspannin PF00335.15 KII91833.1 - 0.049 12.9 11.4 0.011 14.9 5.4 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF3899 PF13038.1 KII91833.1 - 0.64 10.2 3.6 24 5.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF2108 PF09881.4 KII91833.1 - 0.65 9.8 6.3 0.79 9.5 3.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2108) DUF1469 PF07332.6 KII91833.1 - 2.9 7.6 7.0 7.8 6.2 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) PIG-F PF06699.6 KII91834.1 - 5.2e-32 111.3 10.7 8.4e-32 110.6 6.6 1.9 1 1 1 2 2 2 1 GPI biosynthesis protein family Pig-F Hydrolase_6 PF13344.1 KII91835.1 - 5.8e-30 103.1 0.0 1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII91835.1 - 2.1e-17 62.5 0.0 5.9e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KII91835.1 - 3.8e-13 50.3 0.0 5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KII91835.1 - 3.7e-07 30.5 0.0 0.0021 18.2 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KII91835.1 - 0.022 14.1 0.0 0.09 12.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Fungal_trans PF04082.13 KII91836.1 - 1.8e-09 36.8 0.3 3.4e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91836.1 - 0.00033 20.4 12.8 0.00075 19.3 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transaldolase PF00923.14 KII91837.1 - 2.1e-22 79.6 0.0 2.8e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Transaldolase Proteasome PF00227.21 KII91837.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit bZIP_2 PF07716.10 KII91839.1 - 1.7e-05 24.5 7.3 0.0019 18.0 0.2 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KII91839.1 - 0.00012 21.9 7.7 0.0016 18.3 1.3 2.2 2 0 0 2 2 2 2 bZIP transcription factor DUF972 PF06156.8 KII91839.1 - 0.0054 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 KII91839.1 - 0.028 14.1 1.7 0.057 13.1 1.2 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain TSC22 PF01166.13 KII91839.1 - 0.032 14.1 0.3 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.7 KII91839.1 - 0.065 13.0 0.5 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DivIC PF04977.10 KII91839.1 - 0.079 12.4 2.1 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Shugoshin_N PF07558.6 KII91839.1 - 0.094 12.4 6.2 0.26 11.0 1.9 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3280 PF11684.3 KII91839.1 - 0.12 12.6 0.7 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) GOLGA2L5 PF15070.1 KII91839.1 - 0.2 10.0 1.3 0.29 9.5 0.9 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 bZIP_Maf PF03131.12 KII91839.1 - 0.31 11.3 4.0 2.2 8.6 0.3 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Fic PF02661.13 KII91840.1 - 4.7e-12 46.4 0.0 1.7e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Fic/DOC family TIMELESS PF04821.9 KII91841.1 - 5.2e-43 147.2 0.0 2e-42 145.2 0.0 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KII91841.1 - 3.9e-10 39.3 9.8 3.9e-10 39.3 6.8 3.6 2 1 1 3 3 3 1 Timeless protein C terminal region RNA_pol_Rpb4 PF03874.11 KII91841.1 - 0.31 11.0 5.1 2.8 7.9 0.1 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb4 RXT2_N PF08595.6 KII91841.1 - 2.8 7.7 10.5 4.9 6.9 1.2 3.0 2 0 0 2 2 2 0 RXT2-like, N-terminal BTB PF00651.26 KII91842.1 - 1.1e-07 31.8 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Polysacc_synt_4 PF04669.8 KII91843.1 - 7.1e-25 87.4 1.3 7.2e-24 84.2 0.9 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis CinA PF02464.12 KII91844.1 - 9.4e-27 93.3 2.0 1.1e-26 93.0 1.4 1.0 1 0 0 1 1 1 1 Competence-damaged protein WW PF00397.21 KII91846.1 - 4.1e-08 32.9 3.7 4.1e-08 32.9 2.6 1.8 2 0 0 2 2 2 1 WW domain DUF3381 PF11861.3 KII91846.1 - 0.14 11.6 6.7 0.26 10.7 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Usp PF00582.21 KII91847.1 - 1.3e-15 57.8 0.3 1.8e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Universal stress protein family PK_C PF02887.11 KII91847.1 - 0.13 11.8 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Acetyltransf_1 PF00583.19 KII91848.1 - 7e-11 42.0 0.6 1.6e-10 40.8 0.4 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KII91848.1 - 1.6e-10 40.6 0.1 3.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KII91848.1 - 1.3e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII91848.1 - 8.6e-06 25.8 0.1 1.5e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII91848.1 - 2.9e-05 23.9 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII91848.1 - 0.00046 20.0 0.1 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII91848.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KII91848.1 - 0.014 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase F-box-like PF12937.2 KII91849.1 - 0.027 14.1 0.3 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.2 KII91849.1 - 0.087 12.4 0.9 3.6 7.2 0.0 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Pro_CA PF00484.14 KII91850.1 - 3.8e-39 134.1 0.0 4.8e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 KII91850.1 - 0.022 14.6 1.0 0.12 12.2 0.5 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family BTB PF00651.26 KII91851.1 - 3.7e-08 33.3 0.0 7.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF539 PF04400.8 KII91851.1 - 0.046 13.1 2.2 0.1 12.1 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF539) BTB PF00651.26 KII91852.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Thaumatin PF00314.12 KII91853.1 - 3.1e-63 213.0 8.1 3.5e-63 212.9 5.6 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.16 KII91853.1 - 0.041 13.4 0.0 0.098 12.2 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat BTB PF00651.26 KII91854.1 - 2.2e-08 34.0 0.0 4.8e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII91856.1 - 1.8e-10 40.8 0.1 1.4e-09 37.9 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KII91857.1 - 0.00026 20.9 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Chaperone_III PF07824.7 KII91857.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Type III secretion chaperone domain FHA PF00498.21 KII91858.1 - 1.2e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain Beta-lactamase PF00144.19 KII91859.1 - 4.5e-37 127.8 0.0 1.4e-36 126.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase BTB PF00651.26 KII91861.1 - 3.2e-08 33.5 0.0 4.6e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 KII91862.1 - 9.5e-07 28.7 0.0 3.1e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_M90 PF06167.7 KII91862.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Isy1 PF06246.7 KII91863.1 - 9.7e-81 270.9 1.5 1.4e-80 270.4 1.0 1.3 1 1 0 1 1 1 1 Isy1-like splicing family P22_Tail-4 PF11650.3 KII91863.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor MbeD_MobD PF04899.7 KII91863.1 - 0.022 14.6 0.2 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 MbeD/MobD like FAP PF07174.6 KII91863.1 - 0.76 9.0 10.6 1.1 8.5 7.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Sugar_tr PF00083.19 KII91864.1 - 1.4e-109 366.7 25.3 1.6e-109 366.5 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII91864.1 - 6.5e-26 90.8 34.6 3.7e-25 88.3 24.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KII91864.1 - 7.4e-06 24.4 3.8 7.4e-06 24.4 2.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KII91864.1 - 0.00052 18.2 2.1 0.00052 18.2 1.4 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector N2227 PF07942.7 KII91865.1 - 6.7e-91 304.0 0.0 8.4e-91 303.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KII91865.1 - 1.6e-06 27.9 0.0 4.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII91865.1 - 0.0078 16.6 0.0 0.038 14.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII91865.1 - 0.077 13.4 0.0 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Nup88 PF10168.4 KII91865.1 - 0.11 10.3 0.1 0.15 9.8 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component SelP_N PF04592.9 KII91865.1 - 2 7.7 9.2 3.2 7.0 6.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KII91865.1 - 3.5 6.5 7.8 4.9 6.0 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter adh_short PF00106.20 KII91866.1 - 2.2e-19 70.0 0.1 6.8e-19 68.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII91866.1 - 5.3e-08 32.7 0.1 1.1e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KII91866.1 - 1.4e-06 28.2 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII91866.1 - 9.4e-05 22.4 0.6 0.00028 20.9 0.5 1.8 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KII91866.1 - 0.00033 20.1 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KII91866.1 - 0.088 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Molybdopterin PF00384.17 KII91867.1 - 3.1e-67 227.1 0.0 2.2e-66 224.3 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KII91867.1 - 1.7e-19 69.3 0.2 4.3e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KII91867.1 - 4.6e-19 67.3 0.1 1.5e-18 65.7 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KII91867.1 - 2e-15 56.6 0.1 5.5e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KII91867.1 - 7e-09 35.3 0.5 7e-09 35.3 0.4 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KII91867.1 - 0.0038 16.9 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain JAB PF01398.16 KII91869.1 - 8.2e-16 57.7 0.0 8.2e-16 57.7 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KII91869.1 - 6.4e-12 45.4 0.1 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KII91869.1 - 7.6e-08 31.8 0.0 5.5e-07 29.1 0.0 2.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF357 PF04010.8 KII91869.1 - 0.00077 19.1 0.3 0.0019 17.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF357) MIP-T3 PF10243.4 KII91869.1 - 0.005 15.3 27.3 0.0071 14.8 18.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RNase_PH PF01138.16 KII91870.1 - 2.2e-21 76.5 0.0 1.4e-20 73.9 0.0 2.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 Glyco_transf_90 PF05686.7 KII91871.1 - 9.4e-14 50.8 1.7 2.2e-11 43.1 0.4 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 adh_short PF00106.20 KII91872.1 - 9.8e-29 100.4 2.2 1.3e-28 100.0 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII91872.1 - 1.4e-19 70.8 0.1 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII91872.1 - 9.2e-08 31.9 0.9 1.4e-07 31.3 0.6 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KII91872.1 - 0.12 11.9 0.4 0.22 11.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_43 PF04616.9 KII91874.1 - 3.3e-71 239.7 0.7 5.3e-71 239.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TPR_11 PF13414.1 KII91875.1 - 4.8e-12 45.3 4.7 8.8e-12 44.5 3.3 1.4 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 KII91875.1 - 1.3e-08 34.4 0.0 2.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 KII91875.1 - 5.5e-06 25.8 5.1 0.013 15.3 1.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII91875.1 - 2.3e-05 23.7 5.7 0.00015 21.2 2.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII91875.1 - 0.00042 20.8 1.5 0.044 14.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII91875.1 - 0.0008 19.8 0.9 0.23 12.2 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII91875.1 - 0.0028 17.5 5.0 0.087 12.7 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII91875.1 - 1.1 9.6 3.2 1.7 9.0 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KII91875.1 - 4 7.4 5.0 1.9 8.4 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 KII91876.1 - 3.3e-33 115.4 0.4 4.6e-33 114.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII91876.1 - 3.9e-31 108.2 0.5 6e-31 107.5 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91876.1 - 3.1e-18 66.0 0.2 1.1e-17 64.3 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KII91876.1 - 5e-05 22.8 0.2 6e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KII91876.1 - 0.0099 15.5 0.1 0.16 11.6 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KII91876.1 - 0.012 15.6 0.5 0.025 14.5 0.4 1.7 1 1 0 1 1 1 0 NADH(P)-binding Cas_Cas02710 PF09670.5 KII91876.1 - 0.073 11.6 0.0 1.7 7.1 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) Cation_efflux PF01545.16 KII91877.1 - 5.2e-11 42.1 0.5 8.2e-11 41.4 0.3 1.3 1 0 0 1 1 1 1 Cation efflux family SURF6 PF04935.7 KII91878.1 - 3.9e-36 124.3 51.1 3.9e-36 124.3 35.4 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 KII91878.1 - 1.3e-22 79.6 8.2 1.3e-22 79.6 5.7 5.8 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 PTPA PF03095.10 KII91879.1 - 3.4e-116 387.6 0.0 4.1e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNA_polI_A14 PF08203.6 KII91879.1 - 0.035 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Chitin_synth_2 PF03142.10 KII91880.1 - 1.2e-242 806.0 0.4 1.6e-242 805.5 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KII91880.1 - 4.3e-162 540.6 0.0 7.2e-162 539.9 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KII91880.1 - 7.8e-18 63.9 0.6 3.9e-17 61.7 0.3 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KII91880.1 - 2.7e-14 52.7 0.0 3e-07 30.1 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KII91880.1 - 3.9e-13 49.7 0.0 1.8e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KII91880.1 - 3.6e-12 46.3 5.6 1e-11 44.9 2.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KII91880.1 - 0.018 14.7 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF826 PF05696.6 KII91880.1 - 0.11 12.6 0.1 0.41 10.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF826) AAA_29 PF13555.1 KII91880.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.18 KII91881.1 - 2.4e-66 223.9 22.1 1.5e-36 126.2 3.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII91881.1 - 4.4e-61 205.1 0.1 5.1e-30 104.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KII91881.1 - 3.1e-15 56.0 0.4 1.3e-05 24.5 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KII91881.1 - 2.1e-11 44.7 0.0 0.00041 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KII91881.1 - 6.9e-10 39.2 1.9 0.00017 21.6 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KII91881.1 - 1.3e-09 38.2 0.8 0.0021 18.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KII91881.1 - 2.7e-09 37.4 0.0 0.3 10.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_10 PF12846.2 KII91881.1 - 4.7e-09 36.1 0.1 0.089 12.2 0.0 4.2 4 0 0 4 4 4 2 AAA-like domain AAA_29 PF13555.1 KII91881.1 - 1e-08 34.5 0.3 0.007 15.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KII91881.1 - 2.2e-08 33.7 0.1 0.34 10.3 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein ABC_ATPase PF09818.4 KII91881.1 - 2.5e-08 32.9 0.1 0.00019 20.1 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 KII91881.1 - 2.6e-07 30.9 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KII91881.1 - 3.1e-06 26.4 0.0 0.1 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KII91881.1 - 5.1e-06 26.0 1.0 0.074 12.4 0.0 4.1 3 1 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KII91881.1 - 1.3e-05 24.8 0.0 0.18 11.2 0.0 2.8 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KII91881.1 - 1.5e-05 24.1 0.2 0.035 13.2 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_5 PF07728.9 KII91881.1 - 2e-05 24.3 0.1 0.16 11.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KII91881.1 - 2.1e-05 24.1 0.2 0.18 11.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 KII91881.1 - 7.8e-05 22.6 0.2 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 SbcCD_C PF13558.1 KII91881.1 - 0.00011 22.0 0.2 0.32 10.9 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 KII91881.1 - 0.00047 19.8 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF2075 PF09848.4 KII91881.1 - 0.00053 19.0 0.0 0.12 11.2 0.0 2.4 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KII91881.1 - 0.00059 19.8 0.2 2.3 8.1 0.1 3.7 3 1 1 4 4 2 1 AAA domain AAA_14 PF13173.1 KII91881.1 - 0.0009 19.1 0.0 0.53 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KII91881.1 - 0.0016 18.3 3.3 0.75 9.6 0.2 2.9 2 2 0 2 2 2 2 AAA domain MobB PF03205.9 KII91881.1 - 0.0025 17.5 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KII91881.1 - 0.0031 16.9 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 KII91881.1 - 0.0032 17.8 0.1 2.9 8.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII91881.1 - 0.0048 17.0 0.0 2.9 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KII91881.1 - 0.0052 15.9 0.1 6.2 5.9 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KII91881.1 - 0.0071 15.8 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KII91881.1 - 0.0087 15.7 0.1 6.1 6.4 0.0 2.8 3 0 0 3 3 2 0 NACHT domain PRK PF00485.13 KII91881.1 - 0.014 14.9 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KII91881.1 - 0.014 14.2 0.1 2 7.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.7 KII91881.1 - 0.015 14.9 0.2 7.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF3987 PF13148.1 KII91881.1 - 0.02 13.4 0.0 1.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.15 KII91881.1 - 0.022 13.4 0.0 1.4 7.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 KII91881.1 - 0.022 13.6 0.0 0.78 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KII91881.1 - 0.022 14.6 0.0 5.9 6.8 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase KaiC PF06745.8 KII91881.1 - 0.025 13.7 0.8 4.9 6.2 0.0 3.0 3 0 0 3 3 3 0 KaiC AAA_13 PF13166.1 KII91881.1 - 0.039 12.4 0.0 8.2 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain CobU PF02283.11 KII91881.1 - 0.042 13.2 0.1 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase T2SE PF00437.15 KII91881.1 - 0.046 12.6 0.0 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 KII91881.1 - 0.05 13.6 0.0 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Miro PF08477.8 KII91881.1 - 0.063 13.7 0.0 23 5.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 KII91881.1 - 0.066 12.7 0.1 5.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CoaE PF01121.15 KII91881.1 - 0.079 12.3 0.2 15 4.9 0.0 2.5 2 0 0 2 2 2 0 Dephospho-CoA kinase Thymidylate_kin PF02223.12 KII91881.1 - 0.084 12.2 0.0 8.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Ribosomal_60s PF00428.14 KII91883.1 - 5e-28 97.3 10.6 6.3e-28 97.0 7.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Metallophos_2 PF12850.2 KII91884.1 - 6.5e-09 35.8 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KII91884.1 - 4.5e-08 32.7 5.1 1.1e-07 31.5 3.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KII91885.1 - 6.2e-09 35.1 0.0 1.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91885.1 - 0.00045 20.0 3.1 0.00078 19.3 2.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KII91886.1 - 6.7e-07 29.1 6.5 1e-06 28.5 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KII91887.1 - 1.9e-36 125.5 32.5 1.9e-36 125.5 22.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII91887.1 - 8.9e-15 54.2 23.0 1.1e-13 50.6 15.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KII91887.1 - 1.5e-07 30.0 1.1 2.2e-07 29.4 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KII91887.1 - 1.4 6.8 7.5 4.8 5.1 2.9 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.27 KII91889.1 - 1.8e-35 119.4 12.5 6.3e-07 29.0 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 KII91889.1 - 2.4e-16 59.4 0.0 3.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KII91889.1 - 0.073 11.1 1.4 0.75 7.8 0.1 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PI-PLC-X PF00388.14 KII91890.1 - 3.4e-52 175.7 0.0 6.9e-52 174.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KII91890.1 - 1e-39 135.1 0.1 2e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KII91890.1 - 3.5e-07 30.1 0.2 0.21 11.6 0.0 3.5 3 0 0 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 KII91890.1 - 1.2e-06 28.5 0.7 3.6e-06 27.0 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair C2 PF00168.25 KII91890.1 - 2.3e-06 27.3 0.0 7.8e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 C2 domain EF-hand_10 PF14788.1 KII91890.1 - 5.7e-05 22.7 0.7 0.00019 21.0 0.5 2.0 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KII91890.1 - 0.00024 20.1 0.6 0.23 10.8 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KII91890.1 - 0.0021 17.7 1.1 0.3 11.0 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain Chlam_OMP6 PF03504.8 KII91890.1 - 0.019 15.1 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 F-box-like PF12937.2 KII91891.1 - 4.5e-05 23.0 0.3 0.00024 20.7 0.2 2.3 1 0 0 1 1 1 1 F-box-like Beta-lactamase PF00144.19 KII91892.1 - 2.3e-43 148.4 1.1 8.3e-43 146.6 0.7 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KII91892.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase MMR_HSR1 PF01926.18 KII91897.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KII91897.1 - 0.00061 20.2 0.0 0.01 16.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 KII91897.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KII91897.1 - 0.0027 17.1 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KII91897.1 - 0.0045 16.2 0.0 0.042 13.0 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 KII91897.1 - 0.0082 15.7 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KII91897.1 - 0.0083 16.9 0.0 0.021 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KII91897.1 - 0.021 14.9 0.0 0.067 13.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 KII91897.1 - 0.049 12.3 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.1 KII91897.1 - 0.066 13.5 0.1 0.88 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 KII91897.1 - 0.079 12.3 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KII91897.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HCV_NS5a_1a PF08300.8 KII91899.1 - 0.064 13.1 0.2 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain DUF2326 PF10088.4 KII91905.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) DUF4488 PF14869.1 KII91905.1 - 0.053 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) DUF1843 PF08898.5 KII91907.1 - 0.072 13.1 0.6 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Seryl_tRNA_N PF02403.17 KII91907.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PIF1 PF05970.9 KII91908.1 - 4.7e-27 94.8 0.1 4.4e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 KII91908.1 - 1.5e-12 47.5 0.5 2.5e-05 23.9 0.4 3.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KII91908.1 - 1.5e-05 25.0 0.1 0.00015 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII91908.1 - 0.0003 20.9 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII91908.1 - 0.0005 19.5 0.4 0.0086 15.5 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain DEAD PF00270.24 KII91908.1 - 0.00055 19.4 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_19 PF13245.1 KII91908.1 - 0.00057 19.5 0.9 0.0017 18.0 0.6 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KII91908.1 - 0.0011 18.5 0.0 0.5 9.8 0.0 2.4 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 KII91908.1 - 0.0018 17.5 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Mg_chelatase PF01078.16 KII91908.1 - 0.0038 16.4 0.1 0.0061 15.7 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KII91908.1 - 0.0085 15.5 0.0 0.091 12.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 KII91908.1 - 0.011 15.4 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KII91908.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KII91908.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KII91908.1 - 0.043 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KII91908.1 - 0.062 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KII91908.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KII91908.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 KII91908.1 - 0.14 11.0 0.0 0.55 9.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KII91908.1 - 0.16 11.4 0.0 9.2 5.7 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KII91908.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BNIP2 PF12496.3 KII91908.1 - 0.68 10.1 4.8 1.3 9.1 3.3 1.7 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PIF1 PF05970.9 KII91909.1 - 0.0033 16.4 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Dispanin PF04505.7 KII91909.1 - 0.022 14.2 0.1 0.022 14.2 0.1 1.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein SR-25 PF10500.4 KII91909.1 - 0.44 9.9 11.8 0.077 12.4 4.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rot1 PF10681.4 KII91910.1 - 2.8e-54 183.6 0.0 3.2e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal HOASN PF14515.1 KII91915.1 - 0.057 13.7 0.3 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices Herpes_ORF11 PF04797.8 KII91915.1 - 0.26 9.7 0.0 0.41 9.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein zf-CCHC PF00098.18 KII91915.1 - 0.88 9.6 3.1 1.8 8.6 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 KII91923.1 - 1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KII91923.1 - 6.2e-06 26.6 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KII91923.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease MAD PF05557.8 KII91923.1 - 0.045 11.8 0.1 0.06 11.4 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein ECM11 PF15463.1 KII91928.1 - 0.028 14.6 0.1 0.028 14.6 0.0 2.3 3 1 0 3 3 3 0 Extracellular mutant protein 11 Metal_CEHH PF14455.1 KII91928.1 - 0.086 12.2 0.7 0.16 11.3 0.5 1.3 1 0 0 1 1 1 0 Predicted metal binding domain zf-MYND PF01753.13 KII91929.1 - 0.00045 20.0 9.8 0.00045 20.0 6.8 2.1 2 0 0 2 2 2 1 MYND finger Zn_clus PF00172.13 KII91932.1 - 1.6e-05 24.6 9.0 3e-05 23.8 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KII91932.1 - 0.078 12.7 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold PDE6_gamma PF04868.7 KII91935.1 - 0.1 12.4 3.2 0.16 11.8 2.2 1.3 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit COXG PF06240.8 KII91937.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Glyco_hydro_16 PF00722.16 KII91941.1 - 6.2e-05 22.3 0.1 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_65m PF03632.10 KII91942.1 - 7.6e-90 301.2 0.7 3.7e-89 299.0 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KII91942.1 - 2.9e-32 111.9 0.0 9.8e-32 110.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 KII91942.1 - 5.5e-10 39.1 6.7 5.9e-10 39.0 0.5 2.8 2 0 0 2 2 2 1 F5/8 type C domain Glyco_hydro_65C PF03633.10 KII91942.1 - 0.00049 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain DUF2152 PF10222.4 KII91942.1 - 0.18 9.9 0.0 0.42 8.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2152) BTB PF00651.26 KII91943.1 - 0.0073 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-RING-like PF08746.6 KII91953.1 - 0.079 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 RING-like domain BTB PF00651.26 KII91953.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Pkinase PF00069.20 KII91955.1 - 8.9e-07 28.3 0.0 9.6e-06 24.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91955.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3022 PF11226.3 KII91955.1 - 0.025 14.4 0.2 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Carn_acyltransf PF00755.15 KII91956.1 - 2.3e-167 557.7 0.0 2.7e-167 557.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase PF00069.20 KII91958.1 - 0.00033 19.8 0.0 0.00067 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII91958.1 - 0.025 13.6 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase AMP-binding PF00501.23 KII91960.1 - 7.8e-95 317.7 0.2 7.8e-95 317.7 0.2 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII91960.1 - 1e-21 77.6 0.3 2.2e-20 73.3 0.1 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 KII91960.1 - 0.15 11.7 0.0 0.51 10.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) HNH_2 PF13391.1 KII91961.1 - 2.3e-09 36.8 0.4 4.1e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_1 PF00232.13 KII91962.1 - 2.4e-157 523.7 0.1 3.1e-157 523.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KII91962.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core FMN_red PF03358.10 KII91962.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Peroxin-3 PF04882.7 KII91963.1 - 3.6e-96 322.5 0.0 4.3e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 UCR_6-4kD PF08997.5 KII91964.1 - 0.22 11.2 0.2 0.22 11.2 0.1 1.6 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein RhoGAP PF00620.22 KII91965.1 - 2.5e-07 30.4 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FTZ PF03867.9 KII91966.1 - 0.015 14.5 0.1 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DUF35_N PF12172.3 KII91966.1 - 0.67 9.9 3.3 1.8 8.5 1.5 2.2 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DEAD PF00270.24 KII91969.1 - 7.6e-13 48.3 0.0 2.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII91969.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain ResIII PF04851.10 KII91969.1 - 0.039 13.7 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Oxidored_FMN PF00724.15 KII91970.1 - 1.7e-78 264.0 0.0 8.4e-78 261.7 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII91971.1 - 4.7e-97 325.0 0.0 5.4e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N PF00107.21 KII91972.1 - 4.1e-15 55.4 0.0 7.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KII91972.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_FMN PF00724.15 KII91973.1 - 6.8e-91 304.7 0.0 7.8e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 KII91975.1 - 1.8e-89 300.0 0.0 2.1e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.18 KII91976.1 - 5.7e-08 32.7 0.5 1.5e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KII91976.1 - 2.4e-05 23.6 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KII91976.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 KII91976.1 - 0.03 13.6 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_Tyr PF07714.12 KII91976.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 KII91976.1 - 0.13 11.2 0.0 0.4 9.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferritin_2 PF13668.1 KII91977.1 - 2.7e-50 169.8 1.7 4.5e-50 169.1 1.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.1 KII91977.1 - 0.006 17.0 2.1 0.043 14.3 1.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4439) Rubrerythrin PF02915.12 KII91977.1 - 0.18 12.1 0.3 0.64 10.3 0.3 1.9 1 1 1 2 2 2 0 Rubrerythrin F-box-like PF12937.2 KII91979.1 - 2.2e-07 30.4 1.9 8.1e-07 28.6 1.3 2.1 1 0 0 1 1 1 1 F-box-like APG5 PF04106.7 KII91980.1 - 1e-45 155.6 0.0 1.3e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Fungal_trans PF04082.13 KII91982.1 - 4.9e-07 28.8 1.5 8.4e-07 28.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII91982.1 - 9.7e-05 22.2 10.0 0.00017 21.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KII91982.1 - 0.78 9.0 11.3 1.1 8.5 7.8 1.2 1 0 0 1 1 1 0 Vta1 like TPT PF03151.11 KII91983.1 - 1.2e-29 102.9 9.3 1.2e-29 102.9 6.5 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KII91983.1 - 6.1e-08 32.7 32.7 9.4e-05 22.4 7.9 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KII91983.1 - 6.1e-07 28.6 19.6 2.1e-06 26.9 12.4 2.1 1 1 1 2 2 2 2 UAA transporter family Peptidase_C12 PF01088.16 KII91986.1 - 5e-54 182.7 0.0 8.1e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 T2SF PF00482.18 KII91986.1 - 0.0091 15.8 0.9 3.3 7.6 0.0 2.3 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein F Med31 PF05669.7 KII91987.1 - 5.3e-34 116.0 3.6 6.3e-34 115.7 2.5 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 KII91987.1 - 0.12 12.0 2.8 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat Aldo_ket_red PF00248.16 KII91988.1 - 2.4e-51 174.2 0.0 3e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII91989.1 - 8.9e-49 165.8 0.0 1.1e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Antimicrobial_6 PF08036.6 KII91989.1 - 0.077 12.7 1.4 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide F-box-like PF12937.2 KII91990.1 - 3.6e-08 33.0 1.5 6.5e-08 32.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like TMF_TATA_bd PF12325.3 KII91990.1 - 0.029 14.1 0.7 0.038 13.7 0.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RasGAP_C PF03836.10 KII91990.1 - 0.047 13.3 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 RasGAP C-terminus CENP-F_leu_zip PF10473.4 KII91990.1 - 0.068 13.0 0.3 0.094 12.5 0.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KII91990.1 - 0.092 11.9 0.2 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Aldo_ket_red PF00248.16 KII91992.1 - 4.2e-51 173.4 0.0 5.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 KII91992.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 KII91993.1 - 2.8e-48 164.1 0.0 3.3e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 KII91993.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 KII91994.1 - 5.5e-21 75.1 2.6 1e-20 74.3 1.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII91994.1 - 3.7e-10 39.7 0.6 4.7e-10 39.4 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII91994.1 - 5.1e-09 36.2 0.0 6.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII91994.1 - 1.3e-06 28.0 0.1 2.3e-06 27.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KII91994.1 - 0.0056 16.0 0.3 0.52 9.7 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.1 KII91994.1 - 0.066 13.2 1.4 0.16 11.9 1.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding YtfJ_HI0045 PF09695.5 KII91994.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) MspA PF09203.6 KII91994.1 - 0.13 11.6 1.0 8 5.8 0.0 2.3 2 1 0 2 2 2 0 MspA ETF PF01012.16 KII91994.1 - 0.23 11.1 3.4 0.47 10.1 2.4 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain TrkA_N PF02254.13 KII91994.1 - 0.38 10.7 2.2 0.43 10.5 0.3 2.0 2 1 0 2 2 2 0 TrkA-N domain Sugar_tr PF00083.19 KII91995.1 - 1.7e-78 264.2 22.4 2e-78 263.9 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII91995.1 - 6.8e-19 67.7 38.7 4.3e-13 48.7 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KII91995.1 - 0.21 11.6 11.5 0.098 12.6 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) KH_3 PF13014.1 KII91996.1 - 0.042 13.5 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 KH domain zf-CCCH PF00642.19 KII91996.1 - 0.051 13.2 0.3 0.051 13.2 0.2 1.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 KII91997.1 - 6.7e-07 28.8 2.4 6.7e-07 28.8 1.7 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII91997.1 - 0.014 15.3 1.0 0.031 14.2 0.7 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Cytochrom_C550 PF14495.1 KII91997.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain HTH_21 PF13276.1 KII91998.1 - 0.084 12.8 0.7 3.2 7.8 0.3 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_32 PF13565.1 KII91999.1 - 3.6e-06 27.6 3.2 0.0012 19.5 0.1 2.7 2 1 1 3 3 3 2 Homeodomain-like domain HTH_21 PF13276.1 KII91999.1 - 0.00014 21.8 0.8 0.08 12.9 0.3 2.3 2 0 0 2 2 2 2 HTH-like domain DUF218 PF02698.12 KII92000.1 - 2.3e-05 23.9 0.1 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Fungal_trans PF04082.13 KII92001.1 - 2.7e-17 62.5 0.4 5e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII92001.1 - 6.1e-07 29.2 11.1 6.1e-07 29.2 7.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KII92001.1 - 1.9e-06 27.8 4.1 1.9e-06 27.8 2.8 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII92001.1 - 4.9e-05 23.3 20.7 7.5e-05 22.7 3.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII92001.1 - 0.0013 18.9 4.9 0.0013 18.9 3.4 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KII92001.1 - 0.0099 15.7 2.4 0.0099 15.7 1.7 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII92001.1 - 0.015 15.4 4.1 0.86 9.8 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII92001.1 - 0.69 10.2 5.8 5.6 7.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Hydrolase_6 PF13344.1 KII92002.1 - 2.7e-22 78.5 0.0 4.7e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII92002.1 - 2e-20 72.2 0.2 2.6e-19 68.6 0.0 2.6 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 KII92002.1 - 7.9e-05 22.9 0.0 0.0087 16.2 0.0 2.7 2 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII92002.1 - 0.00011 22.6 0.1 0.098 13.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMG_box PF00505.14 KII92004.1 - 1.4e-08 34.8 0.3 2.4e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII92004.1 - 0.055 13.8 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Mgm101p PF06420.7 KII92006.1 - 0.14 11.4 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Mgm101p PF06420.7 KII92007.1 - 0.074 12.3 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 RhoGAP PF00620.22 KII92008.1 - 1.8e-29 102.3 0.0 3.6e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 KII92008.1 - 1.6e-28 98.9 0.0 3.2e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain DUF1932 PF09130.6 KII92009.1 - 2.3e-15 56.0 0.7 1.1e-14 53.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 KII92009.1 - 4.2e-09 36.4 0.2 8.3e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KII92009.1 - 2.3e-05 24.7 0.5 6.3e-05 23.3 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KII92009.1 - 0.00023 20.5 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 KII92009.1 - 0.00087 18.7 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KII92009.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KII92009.1 - 0.043 13.4 0.5 0.081 12.5 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KII92009.1 - 0.079 12.6 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain BTB PF00651.26 KII92010.1 - 0.00032 20.6 0.0 0.0013 18.7 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain DUF998 PF06197.8 KII92011.1 - 0.056 12.7 1.2 0.062 12.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2910 PF11139.3 KII92011.1 - 0.058 12.5 0.1 0.067 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) DUF4536 PF15055.1 KII92011.1 - 2.1 8.4 9.4 0.36 10.9 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) F-box-like PF12937.2 KII92012.1 - 5.5e-10 38.8 0.6 1.1e-09 37.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like YCII PF03795.9 KII92013.1 - 6.1e-10 39.1 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 YCII-related domain BTB PF00651.26 KII92013.1 - 6.7e-06 26.0 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TF_Zn_Ribbon PF08271.7 KII92013.1 - 0.053 12.8 0.1 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4182 PF13790.1 KII92013.1 - 0.66 9.8 4.1 0.25 11.1 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) F-box-like PF12937.2 KII92014.1 - 4e-10 39.2 2.1 7.9e-10 38.3 1.5 1.6 1 0 0 1 1 1 1 F-box-like HRDC PF00570.18 KII92014.1 - 0.078 12.6 0.9 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 HRDC domain DUF4628 PF15429.1 KII92014.1 - 0.1 12.0 0.1 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) F-box-like_2 PF13013.1 KII92014.1 - 0.16 11.6 1.4 0.52 10.0 0.9 1.9 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.28 KII92014.1 - 2.2 8.0 5.8 40 4.0 4.0 2.5 1 1 0 1 1 1 0 F-box domain ECH PF00378.15 KII92015.1 - 3.8e-73 245.6 0.3 4.4e-73 245.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KII92015.1 - 0.00098 19.2 0.1 0.0053 16.8 0.0 1.9 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 KII92015.1 - 0.0098 15.6 0.0 0.035 13.8 0.0 1.9 1 1 1 2 2 2 1 Peptidase family S49 RNase_PH PF01138.16 KII92016.1 - 3.9e-14 53.0 0.2 6.4e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Med12 PF09497.5 KII92017.1 - 1.6e-25 88.8 0.1 3.7e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KII92017.1 - 0.0019 16.8 0.0 0.011 14.1 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain DASH_Dad2 PF08654.5 KII92018.1 - 4.2e-13 49.1 0.1 5.2e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 HEAT PF02985.17 KII92019.1 - 2.1e-09 36.6 0.3 0.47 10.6 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.12 KII92019.1 - 8.9e-06 24.9 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII92019.1 - 2.2e-05 23.7 0.0 4.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.1 KII92019.1 - 0.00029 21.0 0.0 0.32 11.3 0.0 3.3 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KII92019.1 - 0.0041 17.5 0.0 16 6.1 0.0 4.2 3 1 0 3 3 3 2 HEAT-like repeat Med14 PF08638.6 KII92020.1 - 2.3e-47 160.7 0.1 7.5e-47 159.1 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 Acetyltransf_1 PF00583.19 KII92022.1 - 1.2e-08 34.7 0.0 3.5e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KII92022.1 - 4.3e-05 23.1 0.1 0.001 18.8 0.1 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KII92022.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 KII92022.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII92022.1 - 0.00091 19.3 0.0 0.0061 16.6 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII92022.1 - 0.0048 16.7 0.0 2.2 8.1 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain PEPCK_ATP PF01293.15 KII92023.1 - 3.8e-216 718.0 0.0 4.5e-216 717.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 KII92023.1 - 0.023 14.1 0.0 0.076 12.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KII92023.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2516 PF10724.4 KII92025.1 - 0.043 13.8 0.4 0.075 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) zf-C3HC4_4 PF15227.1 KII92026.1 - 4.4e-07 29.6 2.0 4.4e-07 29.6 1.4 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KII92026.1 - 5.6e-06 25.9 3.1 5.6e-06 25.9 2.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII92026.1 - 7.3e-06 25.9 3.2 7.3e-06 25.9 2.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII92026.1 - 3.7e-05 23.3 1.4 0.0001 21.9 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KII92026.1 - 9.5e-05 21.9 4.6 0.003 17.1 0.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII92026.1 - 0.0001 22.0 11.3 0.0019 17.9 7.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KII92026.1 - 0.00015 21.3 6.6 0.00059 19.5 2.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KII92026.1 - 0.003 17.6 3.0 0.007 16.4 0.9 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger ADIP PF11559.3 KII92026.1 - 0.01 15.7 0.5 0.12 12.3 0.8 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding HAP1_N PF04849.8 KII92026.1 - 0.028 13.3 0.1 0.04 12.8 0.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region zf-RING_6 PF14835.1 KII92026.1 - 0.033 13.9 0.5 0.065 13.0 0.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF904 PF06005.7 KII92026.1 - 0.067 13.4 1.9 0.13 12.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4047 PF13256.1 KII92026.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) BRO1 PF03097.13 KII92026.1 - 0.086 11.5 0.1 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Taxilin PF09728.4 KII92026.1 - 0.088 11.8 1.5 0.12 11.4 1.0 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF1272 PF06906.6 KII92026.1 - 0.54 10.1 7.0 2 8.3 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) FYVE PF01363.16 KII92026.1 - 0.56 10.1 4.1 2.2 8.2 2.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger Git3 PF11710.3 KII92027.1 - 3.1e-09 36.6 8.9 6.7e-09 35.5 6.2 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KII92027.1 - 0.02 14.6 1.3 0.02 14.6 0.9 2.2 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 KII92027.1 - 0.41 9.4 11.1 0.018 13.9 3.3 1.8 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor ubiquitin PF00240.18 KII92029.1 - 2.8e-171 555.2 28.5 7.8e-34 114.8 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 KII92029.1 - 1.7e-96 315.9 28.1 8.7e-19 66.9 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KII92029.1 - 8.8e-30 102.8 14.0 0.00019 21.5 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KII92029.1 - 5.3e-26 91.2 1.6 0.0026 17.4 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KII92029.1 - 5.8e-17 61.5 5.4 0.15 11.9 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KII92029.1 - 1.6e-16 60.2 3.8 0.23 11.6 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KII92029.1 - 3.2e-13 49.5 0.0 2.1 8.4 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 KII92029.1 - 8.7e-09 34.8 1.9 1.5 7.8 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase FlgD_ig PF13860.1 KII92029.1 - 1.2e-08 34.5 8.0 4.8 7.0 0.0 5.3 5 0 0 5 5 5 5 FlgD Ig-like domain TUG-UBL1 PF11470.3 KII92029.1 - 4.9e-07 29.5 7.9 9.3 6.2 0.0 5.2 5 0 0 5 5 5 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 KII92029.1 - 9.8e-05 22.6 1.9 84 3.6 0.0 5.2 5 0 0 5 5 5 0 ACT domain Big_3_3 PF13750.1 KII92029.1 - 0.00019 20.9 0.0 71 2.7 0.0 4.8 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 KII92029.1 - 0.0011 17.3 17.4 5.5 5.1 0.1 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 KII92029.1 - 0.02 14.7 19.5 13 5.8 0.2 5.6 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 KII92029.1 - 0.029 14.2 38.3 4.6 7.3 1.2 5.3 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 KII92029.1 - 0.086 12.8 10.8 78 3.3 0.1 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain ACP PF06857.6 KII92029.1 - 0.24 11.3 7.0 48 3.9 0.1 5.4 5 0 0 5 5 5 0 Malonate decarboxylase delta subunit (MdcD) CDC48_2 PF02933.12 KII92029.1 - 5.5 6.7 18.6 59 3.4 0.1 5.1 5 0 0 5 5 5 0 Cell division protein 48 (CDC48), domain 2 DUF3781 PF12636.2 KII92029.1 - 6.9 6.7 10.7 2.3e+02 1.8 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 KII92029.1 - 8.5 6.5 17.7 1.2e+02 2.7 0.1 6.9 5 5 0 5 5 5 0 FERM N-terminal domain HMG_box PF00505.14 KII92030.1 - 8e-12 45.2 0.4 3.7e-11 43.1 0.3 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box PF00505.14 KII92032.1 - 1.9e-13 50.4 0.7 2.2e-13 50.2 0.5 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII92032.1 - 0.0024 18.1 0.3 0.0029 17.9 0.2 1.1 1 0 0 1 1 1 1 HMG-box domain Iron_permease PF04120.7 KII92032.1 - 0.04 13.4 0.3 0.044 13.3 0.2 1.0 1 0 0 1 1 1 0 Low affinity iron permease DUF2570 PF10828.3 KII92032.1 - 0.1 12.2 0.2 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Nop25 PF09805.4 KII92033.1 - 5.6e-22 78.2 19.4 5.6e-22 78.2 13.4 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) MAGE_N PF12440.3 KII92033.1 - 9 6.6 14.4 1.6 9.0 0.9 2.7 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal V-SNARE_C PF12352.3 KII92036.1 - 3.6e-16 58.9 0.5 3.6e-16 58.9 0.4 2.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KII92036.1 - 7.9e-07 28.7 0.3 4.5e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 Sec20 AAA_27 PF13514.1 KII92036.1 - 0.038 11.6 6.2 0.65 7.6 2.2 2.0 2 0 0 2 2 2 0 AAA domain DUF3513 PF12026.3 KII92036.1 - 0.077 12.5 0.4 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Plasmid_RAQPRD PF09686.5 KII92036.1 - 0.094 12.7 5.9 0.19 11.8 1.6 2.5 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Transposase_22 PF02994.9 KII92036.1 - 0.1 11.0 1.7 0.097 11.1 0.3 1.5 2 0 0 2 2 2 0 L1 transposable element Wbp11 PF09429.5 KII92036.1 - 0.13 12.2 3.6 0.82 9.6 1.6 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 HALZ PF02183.13 KII92036.1 - 0.19 11.4 2.6 1.4 8.7 0.1 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper OmpH PF03938.9 KII92036.1 - 0.29 11.0 4.2 0.63 9.9 2.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIVA PF05103.8 KII92036.1 - 0.42 10.6 6.8 0.16 12.0 2.5 1.7 2 0 0 2 2 2 0 DivIVA protein DUF106 PF01956.11 KII92036.1 - 0.88 9.0 2.9 2 7.8 2.0 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF106 T2SM PF04612.7 KII92036.1 - 4.6 7.0 7.9 0.72 9.6 0.8 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M Pkinase PF00069.20 KII92037.1 - 4.9e-15 55.3 0.0 6.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92037.1 - 4.1e-08 32.5 0.0 4.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII92037.1 - 0.00012 21.5 0.0 0.0017 17.7 0.0 2.1 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KII92037.1 - 0.00066 19.4 0.1 0.001 18.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII92037.1 - 0.0041 16.2 0.1 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII92037.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 KII92038.1 - 1.7e-17 63.3 0.0 2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII92038.1 - 3.1e-12 46.1 0.0 4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII92038.1 - 0.022 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4219 PF13961.1 KII92039.1 - 0.13 11.6 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) CAP_N PF01213.14 KII92039.1 - 0.31 10.2 2.1 0.4 9.9 1.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 KII92041.1 - 2.5e-16 59.6 0.0 3e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92041.1 - 1.9e-15 56.6 0.0 2.2e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Beta-lactamase PF00144.19 KII92041.1 - 0.011 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase Kinase-like PF14531.1 KII92041.1 - 0.033 13.1 0.0 0.077 11.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Gyro_capsid PF04162.7 KII92041.1 - 0.091 10.9 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Peptidase_M28 PF04389.12 KII92043.1 - 1.5e-26 93.1 0.1 2.7e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KII92043.1 - 1.9e-08 34.0 0.1 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HMG_box PF00505.14 KII92044.1 - 3.2e-13 49.7 0.0 5.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII92044.1 - 0.0029 17.9 0.1 0.0059 16.9 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Peptidase_M28 PF04389.12 KII92045.1 - 2.6e-29 102.2 0.0 4.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KII92045.1 - 9.6e-10 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 bZIP_2 PF07716.10 KII92046.1 - 4.4 7.1 7.3 11 5.9 2.0 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF1856 PF08983.5 KII92047.1 - 0.013 15.6 2.0 0.054 13.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1856) Fez1 PF06818.10 KII92047.1 - 0.083 12.8 1.8 0.11 12.4 0.9 1.6 1 1 0 1 1 1 0 Fez1 DUF3404 PF11884.3 KII92050.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) HMG_box PF00505.14 KII92053.1 - 6.6e-09 35.9 0.6 1.2e-08 35.0 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MIF4G PF02854.14 KII92060.1 - 5.4e-48 163.1 0.1 1.4e-27 96.5 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KII92060.1 - 1.7e-23 83.2 6.2 1.7e-23 83.2 4.3 3.1 4 0 0 4 4 4 1 Up-frameshift suppressor 2 F-box PF00646.28 KII92062.1 - 0.0059 16.2 0.9 0.015 14.9 0.1 2.2 2 0 0 2 2 2 1 F-box domain DUF3750 PF12570.3 KII92062.1 - 0.1 12.8 1.7 0.32 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) F-box PF00646.28 KII92063.1 - 0.0013 18.3 0.2 0.0049 16.4 0.1 2.1 1 0 0 1 1 1 1 F-box domain Cytochrome_CBB3 PF13442.1 KII92064.1 - 0.045 13.9 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III TAT_ubiq PF07706.7 KII92065.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase ubiquitination site Amidohydro_2 PF04909.9 KII92066.1 - 6.4e-08 32.4 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase SMN PF06003.7 KII92066.1 - 0.035 13.1 1.8 0.056 12.5 1.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) p450 PF00067.17 KII92067.1 - 7.4e-71 239.0 0.0 2.4e-53 181.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Yae1_N PF09811.4 KII92068.1 - 4.1e-09 35.8 27.3 3.8e-05 23.1 6.4 3.4 2 1 1 3 3 3 3 Essential protein Yae1, N terminal UPF0565 PF10561.4 KII92068.1 - 0.074 11.9 0.3 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 E1-E2_ATPase PF00122.15 KII92069.1 - 3.4e-27 94.9 0.8 6.3e-27 94.0 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KII92069.1 - 4.1e-25 89.0 0.0 7e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII92069.1 - 1.5e-22 81.0 0.0 6.1e-21 75.8 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KII92069.1 - 4.5e-18 65.2 0.0 9.1e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.16 KII92069.1 - 6.5e-09 35.5 7.4 1.6e-08 34.2 5.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KII92069.1 - 8.1e-06 25.7 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KII92069.1 - 4e-05 22.9 0.0 9e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KII92069.1 - 0.00086 18.9 0.1 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Lactamase_B PF00753.22 KII92071.1 - 2.1e-08 34.0 0.6 4.3e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KII92071.1 - 2.3e-05 24.0 0.2 2.3e-05 24.0 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain AIF_C PF14721.1 KII92072.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ODC_AZ PF02100.12 KII92073.1 - 1.8e-19 69.2 0.0 2.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.15 KII92074.1 - 8.1e-28 95.9 1.3 8.1e-28 95.9 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KII92074.1 - 8.6e-22 76.2 0.1 1.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.17 KII92075.1 - 3.5e-63 213.7 0.0 4.1e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MUG2_C PF08593.5 KII92075.1 - 0.024 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal Form_Nir_trans PF01226.12 KII92076.1 - 4.2e-74 248.5 16.9 4.9e-74 248.3 11.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter TM_helix PF05552.7 KII92076.1 - 0.42 10.3 3.9 5.4 6.7 1.1 2.7 2 0 0 2 2 2 0 Conserved TM helix Oxidored_FMN PF00724.15 KII92078.1 - 2.8e-85 286.2 0.0 3.4e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RRM_2 PF04059.7 KII92079.1 - 2.9e-33 113.7 0.5 6.1e-33 112.6 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 KII92079.1 - 0.00078 19.3 0.1 0.01 15.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII92079.1 - 0.0027 17.3 0.1 0.73 9.5 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S6 PF01250.12 KII92082.1 - 3.1e-11 42.9 0.0 4.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 HAD_2 PF13419.1 KII92083.1 - 2.7e-21 76.5 0.1 3.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII92083.1 - 1.1e-08 34.6 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KII92083.1 - 2.5e-06 28.0 0.0 3.1e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SNase PF00565.12 KII92084.1 - 6.4e-60 200.1 0.8 2.3e-21 76.1 0.1 6.2 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KII92084.1 - 7.7e-23 80.6 0.0 1.3e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Smr PF01713.16 KII92085.1 - 1.9e-14 53.5 0.1 4.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KII92085.1 - 6.8e-10 38.8 1.6 1.9e-09 37.4 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) GatB_Yqey PF02637.13 KII92085.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 GatB domain PAT1 PF09770.4 KII92085.1 - 0.028 12.7 31.5 0.035 12.3 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MdcE PF06833.6 KII92085.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DUF605 PF04652.11 KII92085.1 - 0.17 11.2 18.8 0.2 11.0 13.0 1.2 1 0 0 1 1 1 0 Vta1 like PCEMA1 PF07418.6 KII92085.1 - 0.27 10.5 1.2 0.3 10.3 0.8 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 SGL PF08450.7 KII92087.1 - 7.4e-11 41.8 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region zf-MYND PF01753.13 KII92088.1 - 1.4e-05 24.8 18.4 1.4e-05 24.8 12.7 2.4 2 0 0 2 2 2 1 MYND finger Mg_trans_NIPA PF05653.9 KII92089.1 - 1.5e-17 63.4 11.8 3.6e-09 35.9 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KII92089.1 - 2.3e-05 24.5 6.4 2.3e-05 24.5 4.5 4.5 3 2 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KII92089.1 - 5.6e-05 23.1 25.2 0.0023 17.9 6.6 3.7 3 1 0 3 3 3 2 EamA-like transporter family DUF4131 PF13567.1 KII92089.1 - 0.36 10.2 12.5 4 6.8 0.0 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) IncA PF04156.9 KII92089.1 - 7 6.1 9.5 6.8 6.2 0.1 3.5 4 0 0 4 4 4 0 IncA protein Tcp11 PF05794.8 KII92090.1 - 4.4e-14 52.0 0.0 8.3e-08 31.3 0.0 2.9 2 1 0 2 2 2 2 T-complex protein 11 Se-cys_synth_N PF12390.3 KII92090.1 - 0.045 13.8 2.6 7 6.8 0.1 3.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal zf-MYND PF01753.13 KII92091.1 - 9.1e-06 25.4 13.2 9.1e-06 25.4 9.2 1.9 2 0 0 2 2 2 1 MYND finger Ssl1 PF04056.9 KII92093.1 - 2.2e-71 239.4 0.0 3e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KII92093.1 - 1.2e-14 53.9 9.5 1.2e-14 53.9 6.6 3.2 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 KII92093.1 - 3.1e-12 46.9 0.0 4.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 KII92093.1 - 0.0016 17.7 5.3 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 DUF4428 PF14471.1 KII92093.1 - 5.8 6.7 11.0 2.7 7.8 3.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) EphA2_TM PF14575.1 KII92094.1 - 0.033 14.5 0.0 7 7.1 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Hexapep PF00132.19 KII92094.1 - 0.51 9.9 5.1 1.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF605 PF04652.11 KII92095.1 - 3.1 7.0 17.3 3.5 6.9 12.0 1.1 1 0 0 1 1 1 0 Vta1 like Na_H_Exchanger PF00999.16 KII92097.1 - 8.6e-56 189.0 29.9 1.1e-55 188.7 20.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PPTA PF01239.17 KII92098.1 - 1.1e-10 40.3 14.8 1.3e-07 30.6 0.1 5.6 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat Glyco_hydr_30_2 PF14587.1 KII92099.1 - 3.3e-24 85.5 0.0 6.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Peptidase_C1_2 PF03051.10 KII92100.1 - 1.1e-156 521.7 0.0 1.3e-156 521.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KII92100.1 - 1e-06 28.8 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 KII92100.1 - 0.044 12.3 0.0 0.07 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family SGL PF08450.7 KII92103.1 - 5.1e-09 35.8 0.0 8.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DUF2036 PF09724.4 KII92104.1 - 8.4e-58 196.0 0.0 1.1e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) G-patch_2 PF12656.2 KII92104.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site DUF262 PF03235.9 KII92105.1 - 4e-16 59.6 0.0 7.4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 FUSC PF04632.7 KII92106.1 - 0.0025 16.3 4.4 0.0043 15.5 3.0 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family Pkinase PF00069.20 KII92107.1 - 9.9e-54 182.2 0.0 1.2e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92107.1 - 5.2e-17 61.7 0.0 7.9e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII92107.1 - 6.3e-09 35.9 0.1 1.5e-05 24.8 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII92107.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sec7 PF01369.15 KII92108.1 - 7.4e-23 81.2 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_10 PF15411.1 KII92108.1 - 0.42 10.8 0.0 0.77 9.9 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Flavin_Reduct PF01613.13 KII92109.1 - 3.1e-25 88.8 0.3 4.7e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KII92109.1 - 0.061 12.8 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Fe-ADH PF00465.14 KII92110.1 - 2.8e-66 223.6 0.0 3.5e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KII92110.1 - 2.4e-18 66.3 0.1 3.5e-18 65.8 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.16 KII92111.1 - 5.1e-45 153.7 8.9 1.9e-44 151.8 6.1 1.8 1 1 0 1 1 1 1 Cation efflux family zf-MYND PF01753.13 KII92112.1 - 4.2e-06 26.5 11.3 9.9e-06 25.3 7.8 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KII92112.1 - 0.17 11.5 5.2 0.47 10.1 3.6 1.8 1 0 0 1 1 1 0 HIT zinc finger CHCH PF06747.8 KII92113.1 - 7.3e-07 28.9 4.4 1.1e-06 28.3 3.1 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KII92113.1 - 0.082 13.0 2.4 0.13 12.3 1.7 1.2 1 0 0 1 1 1 0 GCK domain Mito_fiss_reg PF05308.6 KII92113.1 - 3.2 7.0 9.0 4.8 6.4 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MCM PF00493.18 KII92114.1 - 6.4e-138 459.0 0.1 9.3e-138 458.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KII92114.1 - 1.1e-32 113.2 36.9 1.1e-32 113.2 25.6 2.5 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KII92114.1 - 2.2e-15 57.1 0.0 5.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KII92114.1 - 2.2e-07 30.2 0.0 6.4e-06 25.4 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KII92114.1 - 9e-07 28.7 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KII92114.1 - 0.0012 18.4 0.1 0.019 14.5 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KII92114.1 - 0.0016 17.9 0.1 0.0092 15.4 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 KII92114.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sorting_nexin PF03700.8 KII92114.1 - 0.052 13.6 5.5 0.17 11.9 2.5 2.4 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain DUF3128 PF11326.3 KII92115.1 - 6.6e-19 67.8 0.0 9e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Jiv90 PF14901.1 KII92115.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone DSPc PF00782.15 KII92117.1 - 7.2e-29 100.0 0.0 1.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII92117.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2636 PF11120.3 KII92118.1 - 0.033 13.6 0.4 0.063 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) COX2_TM PF02790.10 KII92118.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4218 PF13960.1 KII92119.1 - 9.8e-06 25.0 0.6 2.2e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-TFIIB PF13453.1 KII92119.1 - 1.2 8.4 9.3 0.11 11.6 0.5 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF4616 PF15394.1 KII92120.1 - 0.008 15.2 0.5 0.084 11.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4616) NPV_P10 PF05531.7 KII92120.1 - 0.074 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KII92120.1 - 0.31 8.8 0.9 0.43 8.3 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KII92120.1 - 0.44 10.1 2.6 0.9 9.0 1.8 1.4 1 0 0 1 1 1 0 IncA protein DUF3415 PF11895.3 KII92123.1 - 1.2e-35 121.2 2.9 3.2e-35 119.8 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KII92123.1 - 8.9e-31 107.1 0.0 1.3e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Got1 PF04178.7 KII92125.1 - 2.5e-20 72.7 11.2 2.7e-20 72.6 7.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 KII92125.1 - 0.4 9.5 9.0 0.45 9.4 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF3185 PF11381.3 KII92125.1 - 3.6 7.4 11.9 8.2 6.2 0.2 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3185) U3_assoc_6 PF08640.6 KII92126.1 - 3.9e-24 84.2 0.2 2.1e-23 81.8 0.4 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KII92126.1 - 0.00024 21.4 5.3 2.1 9.2 0.3 6.0 3 1 2 5 5 5 1 Tetratricopeptide repeat Toxin_trans PF07952.7 KII92126.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain TPR_16 PF13432.1 KII92126.1 - 0.4 11.4 5.5 35 5.2 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Adaptin_N PF01602.15 KII92127.1 - 1.2e-22 80.0 0.0 2.5e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 KII92127.1 - 0.028 14.5 0.9 46 4.4 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KII92127.1 - 0.41 11.2 5.1 4.4 7.9 0.1 4.1 5 0 0 5 5 5 0 HEAT-like repeat DUF4098 PF13345.1 KII92128.1 - 0.00056 19.8 6.3 0.00059 19.7 0.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4098) ICMT PF04140.9 KII92132.1 - 6.5e-15 55.1 0.6 6.2e-13 48.7 0.4 2.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII92132.1 - 7.8e-15 54.8 2.4 1.5e-12 47.5 0.1 2.2 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KII92132.1 - 2.6e-06 26.2 0.1 3.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KII92132.1 - 0.063 12.5 0.1 0.093 12.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Tetraspannin PF00335.15 KII92132.1 - 0.067 12.4 0.8 0.11 11.7 0.5 1.3 1 0 0 1 1 1 0 Tetraspanin family PEMT PF04191.8 KII92133.1 - 3.4e-14 52.8 1.3 1.6e-13 50.6 0.1 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KII92133.1 - 3.8e-14 52.6 0.3 1.3e-12 47.7 0.0 2.4 1 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KII92133.1 - 8.1e-07 27.9 0.0 1.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Tetraspannin PF00335.15 KII92133.1 - 0.0019 17.4 0.2 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family ICMT PF04140.9 KII92135.1 - 8.7e-15 54.6 1.3 3e-13 49.7 0.1 2.4 1 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII92135.1 - 7.9e-14 51.6 2.2 9.1e-13 48.2 0.1 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KII92135.1 - 3.8e-06 25.7 0.0 5.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KII92135.1 - 0.0016 17.7 0.1 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tetraspannin PF00335.15 KII92135.1 - 1.2 8.3 5.2 7.2 5.8 3.6 1.9 1 1 0 1 1 1 0 Tetraspanin family Ribosomal_L11_N PF03946.9 KII92136.1 - 7.7e-18 63.7 0.1 1.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KII92136.1 - 1e-13 51.2 0.8 1.8e-13 50.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pab87_oct PF13969.1 KII92136.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Pab87 octamerisation domain Cyclin PF08613.6 KII92137.1 - 9.4e-28 97.5 0.1 2.1e-27 96.3 0.1 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KII92137.1 - 2.6e-05 23.7 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.11 KII92138.1 - 1.2e-16 60.4 36.1 9.9e-16 57.3 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KII92140.1 - 1.1e-37 129.6 0.0 2e-36 125.4 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92140.1 - 1.4e-17 63.6 0.0 2.4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92140.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII92140.1 - 0.032 13.9 0.4 0.086 12.5 0.3 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family CBF PF03914.12 KII92140.1 - 0.063 12.7 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 CBF/Mak21 family Epimerase PF01370.16 KII92141.1 - 7.6e-09 35.3 0.0 7.6e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII92141.1 - 1.2e-05 25.4 0.1 2.1e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KII92141.1 - 2.2e-05 23.8 0.0 5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KII92141.1 - 0.0015 18.8 0.1 0.0051 17.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KII92141.1 - 0.0078 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_3 PF03447.11 KII92141.1 - 0.022 15.1 0.4 0.77 10.1 0.0 2.7 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII92141.1 - 0.047 12.6 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein RabGAP-TBC PF00566.13 KII92142.1 - 1.7e-38 132.2 0.2 2.5e-38 131.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBF PF01758.11 KII92144.1 - 6.6e-47 159.3 13.4 6.6e-47 159.3 9.3 2.0 3 0 0 3 3 3 1 Sodium Bile acid symporter family DUF3169 PF11368.3 KII92144.1 - 0.34 10.0 2.9 8.3 5.5 0.0 2.7 3 1 0 4 4 4 0 Protein of unknown function (DUF3169) NmrA PF05368.8 KII92145.1 - 4.1e-08 32.7 0.0 6.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KII92145.1 - 8.3e-07 29.1 0.5 1.2e-06 28.6 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII92145.1 - 1.5e-05 24.5 0.1 0.011 15.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KII92145.1 - 0.00037 20.8 0.1 0.0019 18.5 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KII92145.1 - 0.0004 19.3 0.1 0.0016 17.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KII92145.1 - 0.004 15.9 0.0 0.011 14.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KII92145.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KII92145.1 - 0.024 14.7 0.1 0.086 12.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3415 PF11895.3 KII92147.1 - 3.1e-37 126.2 1.9 6.8e-37 125.2 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KII92147.1 - 1.5e-30 106.3 0.0 2.4e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.14 KII92149.1 - 2.1e-28 99.4 0.0 2.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII92149.1 - 2.4e-07 30.0 0.0 0.00029 19.8 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 KII92149.1 - 0.0026 16.6 0.0 0.69 8.6 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 KII92149.1 - 0.011 16.1 0.5 0.047 14.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII92149.1 - 0.05 12.5 0.4 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein bZIP_1 PF00170.16 KII92150.1 - 8.2e-07 28.8 4.1 2.1e-06 27.5 2.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KII92150.1 - 0.0016 18.2 5.4 0.0016 18.2 3.8 1.7 2 0 0 2 2 2 1 Basic region leucine zipper zf-C4H2 PF10146.4 KII92150.1 - 0.0061 16.6 1.0 0.009 16.0 0.7 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein DivIVA PF05103.8 KII92150.1 - 0.023 14.7 0.1 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 DivIVA protein HAP1_N PF04849.8 KII92150.1 - 0.034 13.1 0.4 0.034 13.1 0.3 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DivIC PF04977.10 KII92150.1 - 0.041 13.3 1.1 0.089 12.2 0.8 1.5 1 0 0 1 1 1 0 Septum formation initiator Nnf1 PF03980.9 KII92150.1 - 0.056 13.4 0.5 0.14 12.1 0.3 1.7 1 0 0 1 1 1 0 Nnf1 Telomere_reg-2 PF10193.4 KII92150.1 - 0.14 12.4 0.3 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Telomere length regulation protein FAM101 PF15068.1 KII92150.1 - 2.6 7.4 9.3 0.81 9.0 2.9 2.2 1 1 1 2 2 2 0 FAM101 family CotE PF10628.4 KII92151.1 - 0.048 13.0 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) IU_nuc_hydro PF01156.14 KII92152.1 - 1.2e-52 179.1 0.0 1.5e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase WD40 PF00400.27 KII92153.1 - 4.7e-61 200.6 25.6 1.3e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KII92153.1 - 5.7e-05 21.4 6.0 0.054 11.6 0.3 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 KII92153.1 - 0.0011 17.9 0.0 0.16 10.7 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 KII92153.1 - 0.0029 15.9 0.1 0.71 8.1 0.2 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain DUF1416 PF07210.7 KII92153.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PD40 PF07676.7 KII92153.1 - 0.092 12.4 1.1 15 5.3 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat D123 PF07065.9 KII92158.1 - 4.7e-80 268.8 0.0 5.4e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KII92158.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Dynamitin PF04912.9 KII92161.1 - 1.1e-21 77.0 0.1 6.2e-20 71.3 0.0 2.9 2 1 0 2 2 2 1 Dynamitin EzrA PF06160.7 KII92161.1 - 0.02 13.1 0.0 0.038 12.1 0.0 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Laminin_II PF06009.7 KII92161.1 - 0.033 13.9 0.1 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 Laminin Domain II SlyX PF04102.7 KII92161.1 - 0.071 13.4 5.3 0.22 11.9 0.1 3.6 4 0 0 4 4 4 0 SlyX TPR_MLP1_2 PF07926.7 KII92161.1 - 1.6 8.4 4.3 0.51 10.0 0.1 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SNF2_N PF00176.18 KII92162.1 - 9.6e-58 195.3 0.0 1.3e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII92162.1 - 8.6e-11 41.5 0.0 1.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2439 PF10382.4 KII92162.1 - 1.5e-07 31.5 1.7 0.0055 16.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) DEAD PF00270.24 KII92162.1 - 2.7e-07 30.2 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Rad54_N PF08658.5 KII92162.1 - 0.00014 21.6 0.8 0.0097 15.6 0.1 2.6 2 0 0 2 2 2 1 Rad54 N terminal HDA2-3 PF11496.3 KII92162.1 - 0.00027 19.8 0.0 0.00065 18.5 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KII92162.1 - 0.00058 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Lipid_bd PF12888.2 KII92162.1 - 0.17 11.7 0.1 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Lipid-binding putative hydrolase XPG_I PF00867.13 KII92167.1 - 9.5e-19 67.2 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KII92167.1 - 1.9e-05 24.8 0.0 5.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain AAA PF00004.24 KII92170.1 - 1.4e-08 34.9 0.0 5.4e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KII92170.1 - 3.7e-05 22.7 0.0 0.00032 19.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KII92170.1 - 0.00011 22.2 0.1 0.00033 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KII92170.1 - 0.00059 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KII92170.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KII92170.1 - 0.02 14.1 0.0 0.87 8.7 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KII92170.1 - 0.025 14.2 0.1 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KII92170.1 - 0.068 13.9 0.1 0.25 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KII92170.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KII92170.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KII92170.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus FtsK_SpoIIIE PF01580.13 KII92170.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family F-box-like PF12937.2 KII92171.1 - 1.8e-09 37.1 0.8 7.5e-09 35.1 0.6 2.2 1 0 0 1 1 1 1 F-box-like Asparaginase_2 PF01112.13 KII92172.1 - 3.8e-53 180.2 0.0 4.7e-52 176.6 0.0 2.2 1 1 0 1 1 1 1 Asparaginase Ricin_B_lectin PF00652.17 KII92173.1 - 0.00088 19.3 0.1 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.17 KII92174.1 - 0.0014 18.6 0.6 0.0026 17.7 0.4 1.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CMAS PF02353.15 KII92175.1 - 1.4e-33 116.1 0.0 1.8e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KII92175.1 - 1.8e-13 50.3 0.0 4.1e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII92175.1 - 2.2e-11 44.0 0.0 4.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII92175.1 - 2.9e-11 43.9 0.0 5.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII92175.1 - 1.6e-10 41.2 0.0 3.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII92175.1 - 5.5e-10 39.2 0.0 9.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII92175.1 - 4.6e-09 35.8 0.0 7.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KII92175.1 - 2.5e-07 30.9 0.0 6.8e-07 29.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KII92175.1 - 5.6e-06 25.2 0.0 8.9e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.12 KII92175.1 - 4.4e-05 22.6 0.0 8e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 KII92175.1 - 7.7e-05 21.9 0.1 0.00023 20.4 0.0 1.7 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 KII92175.1 - 0.0022 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KII92175.1 - 0.0047 16.5 0.1 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) FtsJ PF01728.14 KII92175.1 - 0.0075 16.2 0.1 0.053 13.4 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.10 KII92175.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MetW PF07021.7 KII92175.1 - 0.012 14.9 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.6 KII92175.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 KII92175.1 - 0.036 13.6 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KII92175.1 - 0.095 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MDM31_MDM32 PF08118.6 KII92176.1 - 1.7e-133 445.7 0.1 1.3e-129 432.9 0.1 3.1 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Ribosomal_S7 PF00177.16 KII92178.1 - 8.6e-40 135.7 0.7 1e-39 135.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pinin_SDK_memA PF04696.8 KII92179.1 - 3.9 7.0 9.9 6.1 6.4 6.9 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Pex24p PF06398.6 KII92180.1 - 2.3e-33 115.4 0.8 7.8e-33 113.7 0.5 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin SNF2_N PF00176.18 KII92184.1 - 7.6e-67 225.2 0.0 1.3e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KII92184.1 - 1.9e-18 66.3 0.0 4.3e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 KII92184.1 - 9.7e-16 57.7 0.0 2.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 KII92184.1 - 1.1e-09 38.0 0.0 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KII92184.1 - 1.8e-07 30.6 7.1 3.8e-07 29.6 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII92184.1 - 7.5e-07 28.8 5.6 1.6e-06 27.8 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII92184.1 - 1.1e-06 28.5 7.1 1.1e-06 28.5 5.0 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII92184.1 - 3.2e-06 26.7 3.9 5.9e-06 25.9 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII92184.1 - 4.9e-06 26.3 8.1 1.1e-05 25.1 5.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.10 KII92184.1 - 7.7e-06 25.8 0.0 2.3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 KII92184.1 - 5.4e-05 22.7 6.3 0.0001 21.8 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KII92184.1 - 0.047 13.4 3.7 0.096 12.4 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KII92184.1 - 0.058 13.5 4.8 0.17 12.0 3.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Nse4_C PF08743.5 KII92185.1 - 1e-27 95.9 0.6 2.2e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KII92185.1 - 1e-19 70.0 0.9 2.4e-19 68.9 0.6 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Sec7 PF01369.15 KII92186.1 - 2e-15 56.9 0.0 2.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain APH PF01636.18 KII92186.1 - 2.5e-09 37.2 1.4 1.1e-06 28.5 1.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII92186.1 - 6.2e-06 25.9 0.1 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KII92186.1 - 1.5e-05 24.3 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KII92186.1 - 0.00098 18.2 0.1 0.0017 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII92186.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 KII92186.1 - 0.055 12.5 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase ARPC4 PF05856.7 KII92187.1 - 1.2e-75 252.5 5.2 1.3e-75 252.4 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.23 KII92188.1 - 6e-30 103.1 0.0 1.7e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MFMR PF07777.6 KII92188.1 - 0.64 9.9 8.5 1.1 9.1 5.9 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR DUF4604 PF15377.1 KII92188.1 - 0.76 9.9 28.2 0.65 10.1 18.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) YL1 PF05764.8 KII92188.1 - 2.6 7.5 24.6 5.9 6.4 17.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein NARP1 PF12569.3 KII92188.1 - 5.2 5.6 18.3 7.3 5.2 12.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Acetyltransf_3 PF13302.1 KII92189.1 - 1.8e-19 70.3 0.0 2.3e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII92189.1 - 1.5e-08 34.5 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KII92189.1 - 1e-07 32.0 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII92189.1 - 6.1e-05 22.9 0.0 0.00061 19.6 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII92189.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII92189.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PX PF00787.19 KII92191.1 - 2e-25 88.7 0.1 3.5e-25 88.0 0.0 1.4 2 0 0 2 2 2 1 PX domain Trs65 PF12735.2 KII92192.1 - 5.2e-27 94.9 1.0 9e-21 74.4 0.1 3.5 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 Ras PF00071.17 KII92194.1 - 2.5e-34 118.0 0.0 2.9e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII92194.1 - 1.2e-12 48.3 0.0 1.6e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KII92194.1 - 0.0059 15.9 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF2763 PF10961.3 KII92194.1 - 0.13 12.7 0.2 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Arch_ATPase PF01637.13 KII92194.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase Ras PF00071.17 KII92195.1 - 4e-34 117.3 0.0 5.1e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII92195.1 - 5e-14 52.8 0.0 7.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KII92195.1 - 0.0017 17.6 0.0 0.26 10.5 0.0 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B AAA_14 PF13173.1 KII92195.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII92195.1 - 0.027 14.1 0.0 0.033 13.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 KII92195.1 - 0.079 12.4 0.0 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HSP70 PF00012.15 KII92197.1 - 6.6e-163 542.8 0.4 6.6e-163 542.8 0.3 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KII92197.1 - 3.6e-11 42.2 2.6 5.9e-11 41.5 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein CRISPR_assoc PF08798.6 KII92197.1 - 0.045 13.5 1.5 0.078 12.7 1.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein ApoO PF09769.4 KII92197.1 - 1.4 8.6 6.3 7.8 6.1 0.8 2.4 1 1 1 2 2 2 0 Apolipoprotein O IPK PF03770.11 KII92197.1 - 3.7 7.1 9.7 43 3.6 0.0 3.4 3 1 0 3 3 3 0 Inositol polyphosphate kinase Ras PF00071.17 KII92198.1 - 2.6e-39 134.2 0.0 3e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII92198.1 - 2.8e-13 50.4 0.0 3.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KII92198.1 - 0.00055 19.2 0.0 0.017 14.3 0.0 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KII92198.1 - 0.0064 15.9 0.2 0.29 10.5 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KII92198.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Glyco_tranf_2_3 PF13641.1 KII92200.1 - 1.6e-25 90.2 0.0 2.3e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KII92200.1 - 1.8e-09 37.5 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KII92200.1 - 4.4e-07 29.3 0.0 1.4e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KII92200.1 - 1.2e-06 28.3 4.6 1.9e-06 27.7 3.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 IBR PF01485.16 KII92201.1 - 1.4e-15 56.8 38.2 6.9e-10 38.6 11.1 3.9 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 KII92201.1 - 1e-06 28.6 5.5 1e-06 28.6 3.8 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII92201.1 - 1.2e-05 24.8 3.9 1.2e-05 24.8 2.7 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII92201.1 - 5.7e-05 22.8 6.5 5.7e-05 22.8 4.5 3.6 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 KII92201.1 - 0.0016 18.0 4.9 0.0016 18.0 3.4 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII92201.1 - 0.006 16.4 2.7 0.006 16.4 1.9 4.3 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII92201.1 - 0.0077 15.9 1.6 0.0077 15.9 1.1 2.8 2 0 0 2 2 2 1 RING-type zinc-finger YL1 PF05764.8 KII92201.1 - 0.98 8.9 6.3 0.13 11.8 1.2 1.8 2 1 0 2 2 2 0 YL1 nuclear protein tRNA-synt_2 PF00152.15 KII92202.1 - 1.5e-89 300.0 0.0 1.9e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KII92202.1 - 5.5e-12 45.3 0.2 3.9e-11 42.6 0.0 2.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KII92202.1 - 6.7e-10 38.5 0.0 1.7e-05 24.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KII92202.1 - 0.0033 17.0 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) PC-Esterase PF13839.1 KII92203.1 - 9.4e-08 32.1 0.1 9.6e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Use1 PF09753.4 KII92204.1 - 4.2e-11 42.7 3.6 1.4e-10 41.0 2.5 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.8 KII92204.1 - 0.58 9.8 3.0 1.3 8.7 0.7 2.3 2 1 0 2 2 2 0 Sec20 DUF3149 PF11346.3 KII92204.1 - 0.7 9.4 4.2 1.2 8.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Use1 PF09753.4 KII92205.1 - 6.7e-06 25.7 1.0 8e-06 25.4 0.7 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Phage_1_1 PF08200.6 KII92206.1 - 0.088 13.0 2.4 0.45 10.7 1.6 2.3 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein DUF812 PF05667.6 KII92206.1 - 0.4 9.1 7.7 0.75 8.2 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tet_JBP PF12851.2 KII92207.1 - 8.1e-05 21.9 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_2_C PF02836.12 KII92211.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain NRDE-2 PF08424.5 KII92212.1 - 0.053 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference PHD_2 PF13831.1 KII92213.1 - 0.0021 17.3 2.1 0.004 16.4 1.5 1.5 1 0 0 1 1 1 1 PHD-finger DUF2296 PF10058.4 KII92213.1 - 0.12 12.0 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Glyco_hydro_2_N PF02837.13 KII92216.1 - 0.006 16.1 0.1 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KII92216.1 - 0.025 15.0 0.1 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KII92216.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain R3H PF01424.17 KII92217.1 - 1.4e-11 43.9 0.0 3.7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KII92217.1 - 6.2e-08 32.2 0.0 1.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KII92217.1 - 0.00031 20.5 1.4 0.0011 18.7 0.1 2.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site CytochromB561_N PF09786.4 KII92217.1 - 0.052 12.0 0.1 0.079 11.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal RF-1 PF00472.15 KII92220.1 - 2.9e-16 59.2 0.4 4.3e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KII92220.1 - 0.05 13.6 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein ALS_ss_C PF10369.4 KII92221.1 - 1.1e-20 73.0 0.1 1.4e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KII92221.1 - 3e-12 45.7 0.0 6.4e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KII92221.1 - 5.6e-09 35.6 0.1 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.20 KII92222.1 - 9.3e-54 182.2 0.0 1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92222.1 - 1.9e-29 102.5 0.0 2.3e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92222.1 - 4.1e-12 45.6 0.0 6e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII92222.1 - 0.00095 18.2 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII92222.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family GATase_5 PF13507.1 KII92223.1 - 1.2e-96 322.5 0.0 1.7e-96 322.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KII92223.1 - 5.2e-49 166.1 1.3 3e-27 95.5 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KII92223.1 - 4e-25 87.8 0.9 1.3e-24 86.2 0.0 2.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Aldo_ket_red PF00248.16 KII92224.1 - 4e-75 252.2 0.0 4.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ChW PF07538.6 KII92224.1 - 0.27 10.7 1.1 0.55 9.7 0.8 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W CMAS PF02353.15 KII92225.1 - 4.6e-61 206.3 0.0 1.1e-60 205.0 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KII92225.1 - 2.8e-10 40.1 0.0 6.4e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII92225.1 - 1.6e-09 38.3 0.0 2.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII92225.1 - 1.3e-05 25.5 0.0 2.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII92225.1 - 5.5e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII92225.1 - 0.00021 21.6 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII92225.1 - 0.00026 20.6 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII92225.1 - 0.00067 19.6 0.1 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII92225.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KII92225.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 KII92225.1 - 0.025 14.1 0.1 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KII92225.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 KII92225.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) HHH_5 PF14520.1 KII92225.1 - 0.087 13.0 0.0 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Abhydrolase_6 PF12697.2 KII92226.1 - 1.1e-19 71.2 0.5 1.3e-19 71.0 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII92226.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.3 KII92227.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) COG5 PF10392.4 KII92228.1 - 1.8e-24 86.1 2.3 1.8e-13 50.5 0.0 3.9 3 0 0 3 3 3 2 Golgi transport complex subunit 5 Vps51 PF08700.6 KII92228.1 - 0.00015 21.5 0.1 0.0017 18.1 0.0 2.9 2 1 0 2 2 2 1 Vps51/Vps67 NAD_kinase PF01513.16 KII92229.1 - 3.3e-66 222.9 0.0 8.5e-66 221.6 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DUF3069 PF11269.3 KII92229.1 - 0.099 12.7 1.4 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) NOA36 PF06524.7 KII92229.1 - 0.26 10.5 3.4 0.42 9.8 2.3 1.2 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.3 KII92229.1 - 0.92 10.1 15.5 0.24 12.0 5.7 2.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal YqeY PF09424.5 KII92231.1 - 1.5e-24 86.4 0.1 1.8e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Yqey-like protein FANCI_S2 PF14676.1 KII92231.1 - 0.056 13.3 0.1 0.13 12.2 0.1 1.6 2 0 0 2 2 2 0 FANCI solenoid 2 zf-rbx1 PF12678.2 KII92232.1 - 2.9e-13 49.7 0.7 5.1e-13 48.9 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KII92232.1 - 2e-11 43.5 6.4 5.7e-11 42.0 4.4 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII92232.1 - 4.8e-07 29.3 2.9 9.6e-07 28.3 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII92232.1 - 2.4e-05 24.2 2.5 2.4e-05 24.2 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII92232.1 - 3.2e-05 23.4 6.6 0.00047 19.7 4.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII92232.1 - 3.6e-05 23.3 2.7 9.9e-05 21.9 2.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KII92232.1 - 6.6e-05 22.6 0.4 0.00015 21.5 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KII92232.1 - 0.00033 20.3 2.7 0.00089 18.9 1.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KII92232.1 - 0.01 15.6 1.9 0.022 14.6 1.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KII92232.1 - 0.067 13.1 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KII92232.1 - 4.1 7.0 4.7 1.2 8.8 1.1 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.6 KII92233.1 - 1.8e-70 238.1 0.0 2.2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KII92233.1 - 2.5e-07 30.9 0.3 0.002 18.2 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 KII92233.1 - 0.00013 21.6 0.0 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KII92233.1 - 0.00019 21.1 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Skp1_POZ PF03931.10 KII92233.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Con-6 PF10346.4 KII92234.1 - 7.3e-44 146.8 10.5 3.6e-14 51.8 0.5 3.1 3 0 0 3 3 3 3 Conidiation protein 6 DUF4349 PF14257.1 KII92234.1 - 0.0017 17.6 1.3 0.002 17.4 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) SpoIIIAH PF12685.2 KII92234.1 - 0.014 14.9 2.6 0.27 10.7 0.0 2.4 2 1 0 2 2 2 0 SpoIIIAH-like protein DUF3359 PF11839.3 KII92234.1 - 4.7 7.6 8.4 6.6 7.1 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) HbrB PF08539.6 KII92235.1 - 2.2e-36 125.1 0.0 3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Pkinase PF00069.20 KII92237.1 - 3.3e-67 226.3 0.0 4.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92237.1 - 1.2e-44 152.3 0.0 1.9e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92237.1 - 3.5e-09 36.0 0.0 1.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KII92237.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KII92237.1 - 0.0057 16.0 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KII92237.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4661 PF15576.1 KII92237.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF4529 PF15032.1 KII92238.1 - 0.084 11.4 0.2 0.18 10.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) MBD_C PF14048.1 KII92239.1 - 0.019 15.5 0.1 0.025 15.1 0.1 1.3 1 1 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF165 PF02592.10 KII92240.1 - 0.073 13.2 0.1 0.087 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 ABC_tran PF00005.22 KII92241.1 - 2.8e-33 115.1 0.0 4.8e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KII92241.1 - 2.1e-27 96.2 4.6 3.6e-27 95.4 3.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KII92241.1 - 9.7e-07 29.0 0.1 0.0072 16.3 0.1 2.5 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KII92241.1 - 4.1e-05 22.9 0.2 0.00046 19.4 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KII92241.1 - 0.00017 21.6 0.1 0.00055 19.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KII92241.1 - 0.0013 18.1 0.3 0.0038 16.7 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KII92241.1 - 0.007 16.5 0.5 0.067 13.3 0.2 2.5 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KII92241.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KII92241.1 - 0.13 12.1 0.0 0.84 9.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KII92241.1 - 0.16 11.0 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 KII92241.1 - 0.17 11.8 0.8 1.5 8.7 0.1 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FA_desaturase PF00487.19 KII92241.1 - 5.9 6.2 7.3 0.81 9.0 0.3 2.6 2 1 0 2 2 2 0 Fatty acid desaturase RRM_1 PF00076.17 KII92242.1 - 7.8e-25 86.3 0.0 9.8e-25 85.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII92242.1 - 7.1e-20 70.7 0.0 8.8e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII92242.1 - 7.7e-11 41.6 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 KII92243.1 - 6.6e-15 55.1 1.6 9.6e-15 54.6 1.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII92243.1 - 4.5e-06 26.9 0.3 5.6e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KII92243.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 DUF3437 PF11919.3 KII92243.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Rz1 PF06085.6 KII92243.1 - 2.6 7.5 5.4 0.5 9.8 1.1 1.8 1 1 0 1 1 1 0 Lipoprotein Rz1 precursor PROL5-SMR PF15621.1 KII92244.1 - 0.53 10.7 16.0 0.6 10.5 9.2 2.0 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Glyco_hydro_16 PF00722.16 KII92245.1 - 6.2e-10 38.6 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SHIPPO-rpt PF07004.7 KII92246.1 - 0.004 17.9 2.0 1 10.3 0.7 2.8 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat Tup_N PF08581.5 KII92246.1 - 0.045 13.9 0.0 0.045 13.9 0.0 4.5 5 1 1 6 6 6 0 Tup N-terminal NIF PF03031.13 KII92247.1 - 5.6e-53 178.8 0.2 6.8e-53 178.5 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KII92247.1 - 0.043 14.0 0.1 0.91 9.7 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Slu7 PF11708.3 KII92248.1 - 0.013 15.2 1.7 0.013 15.2 1.2 1.6 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Pol_alpha_B_N PF08418.5 KII92248.1 - 6.5 6.2 24.6 6 6.3 16.3 1.4 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal PTPLA PF04387.9 KII92249.1 - 3.6e-49 166.3 3.4 7.6e-49 165.2 2.3 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Asp PF00026.18 KII92250.1 - 3.9e-71 239.9 5.0 3.9e-71 239.9 3.5 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII92250.1 - 1.4e-05 25.1 1.9 1.4e-05 25.1 1.3 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Serglycin PF04360.7 KII92250.1 - 0.29 10.8 3.4 0.17 11.6 0.1 2.1 2 1 0 2 2 2 0 Serglycin SHS2_Rpb7-N PF03876.12 KII92251.1 - 1.7e-09 37.6 0.0 3.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pam16 PF03656.8 KII92252.1 - 3e-20 72.2 0.0 8e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Pam16 HR1 PF02185.11 KII92253.1 - 0.023 14.4 3.2 0.023 14.4 2.2 3.0 2 1 1 3 3 3 0 Hr1 repeat DUF4200 PF13863.1 KII92253.1 - 0.086 12.7 28.8 0.073 13.0 11.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 KII92253.1 - 0.1 11.7 2.2 0.13 11.4 1.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 KII92253.1 - 0.14 11.7 27.4 0.021 14.4 7.5 2.1 1 1 1 2 2 2 0 IncA protein Laminin_II PF06009.7 KII92253.1 - 0.16 11.7 11.4 0.55 9.9 3.0 2.6 1 1 2 3 3 3 0 Laminin Domain II Fib_alpha PF08702.5 KII92253.1 - 2.3 8.3 13.1 1.4 9.0 4.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Striatin PF08232.7 KII92253.1 - 2.8 8.2 21.5 63 3.8 14.8 2.1 1 1 0 1 1 1 0 Striatin family DUF3619 PF12279.3 KII92253.1 - 3.5 7.7 13.6 0.09 12.8 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) LMBR1 PF04791.11 KII92253.1 - 4.8 5.6 9.6 5.4 5.4 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PPR_2 PF13041.1 KII92256.1 - 1e-38 131.0 2.1 1.6e-09 37.5 0.0 8.3 5 3 3 8 8 8 8 PPR repeat family PPR_3 PF13812.1 KII92256.1 - 1.2e-28 96.9 3.4 1.8e-05 24.6 0.0 9.6 10 0 0 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.15 KII92256.1 - 1.1e-16 59.5 10.7 3.5e-05 23.4 0.2 7.6 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.2 KII92256.1 - 1.8e-11 43.3 5.8 0.0011 18.3 0.0 7.0 7 1 0 7 7 7 3 PPR repeat ECSIT PF06239.6 KII92256.1 - 0.00081 18.3 0.2 2.2 7.1 0.0 4.6 5 1 1 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway Rad21_Rec8_N PF04825.8 KII92257.1 - 5.5e-43 145.4 0.2 9.2e-43 144.7 0.2 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KII92257.1 - 3.6e-12 45.2 0.1 6.6e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KII92257.1 - 9e-05 22.1 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 ScpA/B protein BTB PF00651.26 KII92258.1 - 1.3e-11 44.4 0.0 5.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain RhoGAP PF00620.22 KII92259.1 - 3.2e-43 146.9 0.2 2.8e-42 143.9 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KII92259.1 - 1.1e-11 44.6 26.8 1.5e-07 31.3 5.7 2.9 3 1 1 4 4 4 2 LIM domain C1_1 PF00130.17 KII92259.1 - 1.4e-06 27.9 7.1 1.4e-06 27.9 4.9 3.5 3 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RICH PF05062.7 KII92259.1 - 0.013 15.6 2.8 4.5 7.4 0.4 2.7 2 0 0 2 2 2 0 RICH domain TMF_TATA_bd PF12325.3 KII92259.1 - 7.2 6.3 18.3 0.44 10.2 1.9 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF35_N PF12172.3 KII92259.1 - 8.5 6.4 8.1 0.25 11.3 0.3 2.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) KTI12 PF08433.5 KII92260.1 - 1.7e-77 260.2 0.0 2e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KII92260.1 - 3.4e-06 26.9 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3419 PF11899.3 KII92261.1 - 7.2e-129 429.8 0.0 9.6e-129 429.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KII92261.1 - 3.5e-09 36.6 0.0 2.3e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII92261.1 - 2e-08 34.6 0.0 2.4e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 KII92261.1 - 4e-08 33.6 0.0 6e-06 26.6 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII92261.1 - 2.3e-07 30.2 0.0 2.6e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KII92261.1 - 6.4e-07 29.9 0.0 1.8e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII92261.1 - 3.5e-06 26.6 0.0 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII92261.1 - 2e-05 24.8 0.0 9.4e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII92261.1 - 0.0018 18.3 0.0 0.12 12.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII92261.1 - 0.029 13.4 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase zf-MYND PF01753.13 KII92262.1 - 1.1e-08 34.7 11.0 1.7e-08 34.1 7.6 1.3 1 0 0 1 1 1 1 MYND finger UPF0560 PF10577.4 KII92262.1 - 0.13 10.5 0.1 0.16 10.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Herpes_UL87 PF03043.9 KII92265.1 - 1.9 6.7 7.1 2.4 6.4 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Baculo_PEP_C PF04513.7 KII92266.1 - 2.9 7.7 7.1 35 4.2 4.9 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hist_deacetyl PF00850.14 KII92267.1 - 1.4e-96 323.4 0.0 2e-96 322.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KII92267.1 - 1.7e-21 76.4 0.0 6.2e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Arb2 domain DUF1749 PF08538.5 KII92267.1 - 0.0025 16.7 0.0 0.006 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF3089 PF11288.3 KII92267.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lactamase_B PF00753.22 KII92268.1 - 1.2e-11 44.6 2.7 1.7e-11 44.1 1.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KII92268.1 - 2.9e-05 23.7 0.1 4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KII92268.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Amidohydro_4 PF13147.1 KII92269.1 - 2.8e-15 57.1 19.2 2e-14 54.2 5.0 4.1 3 2 1 4 4 4 2 Amidohydrolase Amidohydro_1 PF01979.15 KII92269.1 - 8.7e-09 35.4 0.4 5e-05 23.1 0.0 3.8 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 KII92269.1 - 1.4e-08 34.4 3.5 2.4e-08 33.6 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 KII92269.1 - 2.1e-06 27.2 2.5 0.00011 21.5 0.1 2.9 3 1 0 3 3 3 2 Amidohydrolase family Rad10 PF03834.9 KII92270.1 - 7.2e-28 96.0 0.0 1.2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KII92270.1 - 1.2e-09 38.1 0.0 3.8e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain MFS_1 PF07690.11 KII92272.1 - 2e-37 128.7 28.2 2e-37 128.7 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII92272.1 - 4.5e-10 38.6 17.4 4.5e-10 38.6 12.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KII92272.1 - 0.078 11.0 12.5 0.0082 14.3 5.7 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector Transgly_assoc PF04226.8 KII92272.1 - 9.3 6.4 16.8 14 5.8 6.6 3.5 3 0 0 3 3 3 0 Transglycosylase associated protein Amidohydro_4 PF13147.1 KII92273.1 - 1.9e-20 74.0 9.6 6.6e-20 72.2 1.1 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KII92273.1 - 5.8e-14 51.6 0.1 1.3e-09 37.7 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KII92273.1 - 6.8e-07 29.2 0.6 9.7e-05 22.1 0.0 3.5 4 0 0 4 4 4 1 Amidohydrolase family Amidohydro_3 PF07969.6 KII92273.1 - 0.00039 19.7 0.1 0.037 13.2 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase family TRP PF06011.7 KII92274.1 - 2.4e-75 253.7 16.1 3.3e-75 253.3 11.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KII92274.1 - 1.3e-25 90.1 0.3 2.2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.1 KII92274.1 - 0.024 14.8 0.1 0.062 13.4 0.1 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NdhL PF10716.4 KII92274.1 - 0.024 14.4 1.5 0.12 12.1 1.0 2.3 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit OPT PF03169.10 KII92275.1 - 2.8e-165 551.2 43.3 3.2e-165 551.1 30.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF21 PF01595.15 KII92275.1 - 2.1 7.5 8.4 0.46 9.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF21 OSCP PF00213.13 KII92277.1 - 2.7e-39 134.8 2.1 3e-39 134.6 1.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DNA_pol3_a_NI PF14480.1 KII92277.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I Pre-SET PF05033.11 KII92279.1 - 1.3e-21 76.7 5.7 1.3e-21 76.7 3.9 2.3 2 1 0 2 2 2 1 Pre-SET motif SET PF00856.23 KII92279.1 - 5.9e-21 75.4 1.3 1.1e-19 71.3 0.9 2.4 1 1 0 1 1 1 1 SET domain YqbF PF14553.1 KII92279.1 - 0.13 11.9 0.2 0.29 10.8 0.2 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain MgsA_C PF12002.3 KII92280.1 - 4.5e-53 179.3 0.1 7.4e-53 178.6 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 KII92280.1 - 2.2e-17 62.8 0.0 9.9e-17 60.7 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KII92280.1 - 6.2e-16 58.8 0.1 1.8e-15 57.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII92280.1 - 9.5e-08 31.8 0.1 1.7e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KII92280.1 - 5.9e-06 27.0 0.1 2.6e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KII92280.1 - 7.2e-06 25.3 0.2 0.048 12.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KII92280.1 - 7.5e-06 25.5 0.0 0.00026 20.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KII92280.1 - 8.6e-06 25.9 0.1 0.0015 18.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KII92280.1 - 9.4e-06 25.7 0.1 0.0032 17.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta2 PF13177.1 KII92280.1 - 3.3e-05 23.5 0.0 0.012 15.3 0.0 2.4 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KII92280.1 - 8.4e-05 22.4 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII92280.1 - 0.00014 22.1 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KII92280.1 - 0.00058 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 KII92280.1 - 0.00066 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII92280.1 - 0.00087 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KII92280.1 - 0.00089 19.2 0.0 0.0025 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 KII92280.1 - 0.0021 16.8 0.0 0.034 12.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KII92280.1 - 0.007 15.8 0.0 0.072 12.5 0.0 2.6 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 KII92280.1 - 0.0073 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KII92280.1 - 0.022 14.5 1.2 0.043 13.5 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 KII92280.1 - 0.026 14.8 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 KII92280.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 KII92280.1 - 0.039 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Zeta_toxin PF06414.7 KII92280.1 - 0.046 12.8 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KII92280.1 - 0.053 12.9 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KII92280.1 - 0.056 12.6 0.0 0.67 9.1 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KII92280.1 - 0.086 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 KII92280.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arrestin_C PF02752.17 KII92281.1 - 0.051 13.6 0.0 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Peptidase_C15 PF01470.12 KII92282.1 - 7.7e-07 29.1 0.0 0.0043 16.9 0.0 2.9 3 0 0 3 3 3 2 Pyroglutamyl peptidase APS_kinase PF01583.15 KII92283.1 - 4.4e-71 237.6 0.0 5.2e-71 237.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KII92283.1 - 2.9e-05 24.8 0.1 5.2e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII92283.1 - 3.1e-05 23.8 0.0 5.8e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII92283.1 - 4.9e-05 23.6 0.0 7.6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KII92283.1 - 0.0047 16.1 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KII92283.1 - 0.0048 16.3 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.7 KII92283.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 KII92283.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.20 KII92285.1 - 1.3e-65 221.1 0.0 1.6e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92285.1 - 2.9e-47 160.9 0.0 3.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92285.1 - 3.5e-06 26.1 0.0 5.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII92285.1 - 0.00011 21.9 0.0 0.15 11.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KII92285.1 - 0.03 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII92285.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Hexapep PF00132.19 KII92286.1 - 6e-10 38.1 1.7 0.0017 17.7 2.5 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KII92286.1 - 1.3e-08 34.4 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KII92286.1 - 1.1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NOA36 PF06524.7 KII92286.1 - 0.82 8.8 6.1 1.3 8.2 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein Hexapep_2 PF14602.1 KII92286.1 - 1.1 8.9 9.7 0.1 12.1 2.7 2.3 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Sigma70_ner PF04546.8 KII92286.1 - 6 6.4 14.1 9.7 5.7 9.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4502 PF14950.1 KII92287.1 - 1.3e-06 27.8 0.1 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) Laminin_II PF06009.7 KII92288.1 - 0.014 15.1 1.3 0.014 15.1 0.9 1.9 1 1 1 2 2 2 0 Laminin Domain II Imm23 PF15593.1 KII92288.1 - 0.058 13.6 2.5 0.078 13.2 1.7 1.2 1 0 0 1 1 1 0 Immunity protein 23 Syntaxin-6_N PF09177.6 KII92288.1 - 0.62 10.5 5.4 2.7 8.4 3.6 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF3896 PF13035.1 KII92288.1 - 1.1 9.3 6.1 2.2 8.3 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) IncA PF04156.9 KII92288.1 - 1.2 8.7 8.0 0.19 11.3 0.8 1.9 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 KII92288.1 - 1.5 7.8 9.5 1.8 7.5 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 eIF-3c_N PF05470.7 KII92289.1 - 3.4e-182 606.6 28.4 3.4e-182 606.6 19.7 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KII92289.1 - 1.8e-14 53.8 0.1 1.1e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 PCI domain DUF1642 PF07852.6 KII92289.1 - 0.068 13.5 3.8 0.18 12.1 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) CRA PF06589.6 KII92291.1 - 4.9 6.4 5.6 1.8 7.8 0.1 2.5 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Pro_racemase PF05544.6 KII92293.1 - 9.9e-46 156.0 0.0 1.8e-45 155.1 0.0 1.4 1 1 0 1 1 1 1 Proline racemase CAP_GLY PF01302.20 KII92295.1 - 1e-18 66.7 1.7 1.7e-18 66.0 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 KII92295.1 - 0.00015 21.4 111.1 0.026 14.1 9.3 7.2 1 1 5 7 7 7 5 IncA protein DUF3584 PF12128.3 KII92295.1 - 0.00037 17.9 42.2 0.00037 17.9 29.2 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3584) PspA_IM30 PF04012.7 KII92295.1 - 0.003 16.9 9.7 0.003 16.9 6.7 6.2 2 2 3 5 5 5 2 PspA/IM30 family Tropomyosin_1 PF12718.2 KII92295.1 - 0.015 15.1 1.1 0.015 15.1 0.8 7.8 2 2 6 8 8 8 0 Tropomyosin like YlbD_coat PF14071.1 KII92295.1 - 0.039 14.0 0.3 0.039 14.0 0.2 4.1 4 0 0 4 4 4 0 Putative coat protein zf-CCHC_4 PF14392.1 KII92295.1 - 0.15 11.7 10.2 1.1 9.0 2.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 KII92295.1 - 1.4 8.4 3.3 14 5.2 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF1237 PF06824.6 KII92297.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) Tet_JBP PF12851.2 KII92302.1 - 1.4e-11 44.0 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF3966 PF13110.1 KII92303.1 - 0.11 12.3 0.2 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Daxx PF03344.10 KII92303.1 - 1.1 7.6 11.6 0.14 10.5 1.4 2.2 2 0 0 2 2 2 0 Daxx Family YdjO PF14169.1 KII92304.1 - 0.012 15.0 3.2 0.2 11.1 0.2 3.4 3 0 0 3 3 3 0 Cold-inducible protein YdjO RFX5_DNA_bdg PF14621.1 KII92304.1 - 0.025 14.2 0.1 0.066 12.8 0.1 1.6 2 0 0 2 2 2 0 RFX5 DNA-binding domain PhnA_Zn_Ribbon PF08274.7 KII92304.1 - 0.099 12.4 0.2 0.099 12.4 0.1 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-NADH-PPase PF09297.6 KII92304.1 - 0.3 10.6 1.2 13 5.4 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PIF1 PF05970.9 KII92305.1 - 2.3e-13 49.8 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KII92305.1 - 4.9e-09 36.0 0.0 6.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII92305.1 - 5.9e-05 22.7 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KII92305.1 - 0.032 13.7 0.0 0.095 12.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 KII92305.1 - 0.034 13.9 0.1 0.2 11.4 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.8 KII92305.1 - 0.041 12.7 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 KII92305.1 - 0.045 12.3 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KII92305.1 - 0.053 12.9 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Peptidase_C13 PF01650.13 KII92307.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family Helitron_like_N PF14214.1 KII92308.1 - 8.2e-06 25.6 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Peptidase_M91 PF14891.1 KII92308.1 - 0.074 13.1 1.1 0.13 12.3 0.7 1.4 1 1 0 1 1 1 0 Effector protein GAS PF13851.1 KII92310.1 - 0.0065 15.6 2.2 0.012 14.7 1.5 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 KII92310.1 - 0.023 14.5 9.1 0.047 13.5 6.3 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CDC37_N PF03234.9 KII92310.1 - 0.045 14.0 1.6 0.092 13.0 1.1 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ADIP PF11559.3 KII92310.1 - 0.082 12.8 12.2 0.62 9.9 1.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KII92310.1 - 0.25 11.7 2.5 6.9 7.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-H PF05837.7 KII92310.1 - 0.26 11.4 5.4 2.8 8.1 0.6 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.7 KII92310.1 - 0.28 10.9 7.1 0.5 10.1 4.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KII92310.1 - 0.31 10.8 6.8 4.7 7.0 0.1 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 KII92310.1 - 0.32 10.8 3.6 0.27 11.0 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KII92310.1 - 0.34 10.4 10.7 1.5 8.3 7.4 1.9 1 1 0 1 1 1 0 IncA protein vATP-synt_E PF01991.13 KII92310.1 - 1.9 7.6 5.8 2.9 7.0 1.7 2.1 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Tropomyosin_1 PF12718.2 KII92310.1 - 2.4 8.0 9.2 32 4.3 6.3 2.2 1 1 1 2 2 2 0 Tropomyosin like ABC_tran_2 PF12848.2 KII92311.1 - 0.33 10.8 6.1 3.9 7.3 0.0 3.5 4 0 0 4 4 4 0 ABC transporter HAP1_N PF04849.8 KII92312.1 - 0.0018 17.3 0.1 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Uds1 PF15456.1 KII92312.1 - 2.4 8.1 6.6 0.59 10.1 0.9 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Zn_clus PF00172.13 KII92312.1 - 9.8 6.1 12.1 0.87 9.5 0.6 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nsp1_C PF05064.8 KII92313.1 - 0.0053 16.3 2.4 0.062 12.9 0.2 2.7 1 1 1 2 2 2 1 Nsp1-like C-terminal region DUF3584 PF12128.3 KII92313.1 - 0.02 12.2 13.6 0.027 11.8 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Microtub_assoc PF07989.6 KII92313.1 - 0.047 13.5 0.4 0.16 11.8 0.2 1.9 1 1 0 1 1 1 0 Microtubule associated AAA-ATPase_like PF09820.4 KII92313.1 - 0.083 12.0 0.1 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 Predicted AAA-ATPase Sipho_Gp157 PF05565.6 KII92313.1 - 0.14 11.7 5.6 0.11 12.0 2.3 2.0 1 1 0 1 1 1 0 Siphovirus Gp157 Vps5 PF09325.5 KII92313.1 - 0.14 11.3 6.4 0.041 13.1 0.6 2.3 2 1 1 3 3 3 0 Vps5 C terminal like SlyX PF04102.7 KII92313.1 - 0.28 11.5 14.3 8.3 6.8 0.0 5.3 3 2 2 5 5 5 0 SlyX DUF2937 PF11157.3 KII92313.1 - 0.39 10.0 5.9 0.45 9.8 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) BLOC1_2 PF10046.4 KII92313.1 - 0.51 10.5 8.6 0.083 13.0 1.4 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KII92313.1 - 1 8.4 4.7 0.58 9.2 0.9 2.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 KII92313.1 - 1.3 8.6 16.9 2.8 7.4 4.5 2.3 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 KII92313.1 - 2.1 8.4 10.5 1.3 9.1 2.0 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 KII92313.1 - 4.4 6.8 8.9 4.1 6.9 0.1 3.4 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.6 KII92313.1 - 7.6 5.0 13.7 0.59 8.7 4.1 2.1 1 1 2 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.3 KII92313.1 - 9.1 6.1 18.7 11 5.8 3.8 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3732 PF12532.3 KII92314.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) SAP PF02037.22 KII92314.1 - 0.14 11.6 0.0 0.46 10.0 0.0 2.0 1 0 0 1 1 1 0 SAP domain UBN2 PF14223.1 KII92318.1 - 0.00088 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII92318.1 - 0.0048 16.4 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII92319.1 - 6.1e-05 22.7 0.0 6.9e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII92319.1 - 9e-05 22.0 0.0 9.4e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII92320.1 - 0.0012 18.4 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII92321.1 - 0.00055 19.4 0.0 0.00076 19.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII92321.1 - 0.0031 17.2 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type tRNA-synt_2c PF01411.14 KII92325.1 - 4.1e-214 711.9 0.0 5.7e-214 711.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KII92325.1 - 2.5e-17 62.4 0.3 6.2e-17 61.2 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KII92325.1 - 3e-07 30.0 0.5 9.4e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 DHHA1 domain Zn_clus PF00172.13 KII92328.1 - 1.2e-07 31.5 29.8 0.00043 20.1 10.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.16 KII92329.1 - 1.7e-24 86.6 0.0 5.3e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KII92329.1 - 0.00012 21.5 0.0 0.0018 17.7 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KII92329.1 - 0.0023 17.6 0.1 1.7 8.3 0.0 2.8 2 2 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Utp12 PF04003.7 KII92329.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Dip2/Utp12 Family SAM_decarbox PF01536.11 KII92330.1 - 1.5e-83 280.2 0.0 1.4e-53 181.6 0.0 2.2 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase DUF1279 PF06916.8 KII92331.1 - 4.9e-18 65.2 0.0 6.7e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1469 PF07332.6 KII92331.1 - 0.2 11.3 1.2 0.98 9.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) RPEL PF02755.10 KII92332.1 - 5.5e-17 60.5 6.7 4.1e-09 35.4 0.6 2.4 2 0 0 2 2 2 2 RPEL repeat Sigma70_r3 PF04539.11 KII92332.1 - 0.0071 16.2 4.3 0.59 10.0 0.3 2.1 1 1 1 2 2 2 2 Sigma-70 region 3 MEA1 PF06910.6 KII92332.1 - 0.0077 15.9 0.1 0.0096 15.6 0.1 1.1 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Ricin_B_lectin PF00652.17 KII92333.1 - 1.9e-22 79.5 11.6 4.2e-22 78.4 8.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KII92333.1 - 1e-15 57.9 6.7 6.8e-12 45.6 2.3 2.5 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Rax2 PF12768.2 KII92335.1 - 1.2e-87 293.7 26.9 8.6e-71 238.4 1.7 5.4 4 1 1 5 5 5 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 KII92335.1 - 9.5e-10 37.7 0.0 1.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KII92335.1 - 1.7e-07 30.7 0.3 3.4e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2625 PF10946.3 KII92335.1 - 0.0024 16.8 1.5 0.0053 15.7 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF2625 SH3_2 PF07653.12 KII92335.1 - 0.0054 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF938 PF06080.7 KII92335.1 - 0.017 14.6 0.2 0.073 12.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF938) ABC_membrane_3 PF13748.1 KII92335.1 - 0.1 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region EphA2_TM PF14575.1 KII92335.1 - 0.37 11.2 0.0 0.94 9.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-C2H2_2 PF12756.2 KII92336.1 - 8.5e-37 125.3 12.5 1.7e-31 108.3 0.1 3.1 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KII92336.1 - 3.3e-09 36.6 2.0 3.3e-09 36.6 1.4 2.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KII92336.1 - 1.7e-08 34.3 2.1 1.7e-08 34.3 1.4 4.0 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KII92336.1 - 4.2e-05 23.6 22.2 0.078 13.3 0.6 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KII92336.1 - 0.0001 22.0 7.0 0.045 13.6 0.0 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KII92336.1 - 0.00024 21.2 19.6 0.012 15.9 0.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-DBF PF07535.7 KII92336.1 - 0.0074 15.9 1.1 0.0074 15.9 0.8 3.7 4 0 0 4 4 4 1 DBF zinc finger Nop14 PF04147.7 KII92336.1 - 0.72 7.7 7.9 1.2 7.0 5.5 1.3 1 0 0 1 1 1 0 Nop14-like family zf-FCS PF06467.9 KII92336.1 - 1 9.0 6.3 7.1 6.3 0.3 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF3449 PF11931.3 KII92336.1 - 4.5 6.7 16.2 0.15 11.5 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Cwf_Cwc_15 PF04889.7 KII92336.1 - 8.5 6.0 15.8 0.74 9.4 5.8 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PP2C PF00481.16 KII92337.1 - 1.7e-29 103.0 0.0 3.2e-27 95.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KII92337.1 - 0.0068 16.1 0.0 4.2 7.0 0.1 2.4 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) HeH PF12949.2 KII92339.1 - 1.5e-05 24.4 1.7 1.5e-05 24.4 1.2 2.1 2 0 0 2 2 2 1 HeH/LEM domain SAP PF02037.22 KII92339.1 - 0.00084 18.7 0.3 0.0057 16.1 0.2 2.3 1 1 0 1 1 1 1 SAP domain Rho_N PF07498.7 KII92339.1 - 0.016 14.9 0.5 0.03 14.0 0.3 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain CDC27 PF09507.5 KII92339.1 - 0.017 14.3 14.9 0.021 14.0 10.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF605 PF04652.11 KII92339.1 - 7.6 5.8 26.0 10 5.3 18.0 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KII92339.1 - 9.4 4.3 12.9 12 4.0 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CBFB_NFYA PF02045.10 KII92340.1 - 4.1e-29 100.8 7.1 8.5e-29 99.8 4.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_S13 PF00416.17 KII92342.1 - 2.6e-41 140.4 1.3 3.2e-41 140.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KII92342.1 - 0.013 14.1 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 KII92342.1 - 0.15 12.1 0.4 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Dfp1_Him1_M PF08630.5 KII92343.1 - 5.1e-23 81.2 0.0 9.9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KII92343.1 - 5.9e-21 73.8 0.5 1.1e-20 72.9 0.4 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 KII92343.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KII92343.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF1003 PF06210.6 KII92343.1 - 7.3 6.5 8.1 1.6 8.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Spc97_Spc98 PF04130.8 KII92345.1 - 5.4e-51 173.5 0.0 8.9e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family FAD_binding_3 PF01494.14 KII92346.1 - 1.8e-72 244.3 0.1 2.6e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII92346.1 - 3.5e-06 26.1 3.2 0.011 14.7 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII92346.1 - 5.2e-06 26.7 0.2 0.072 13.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII92346.1 - 0.00031 20.7 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII92346.1 - 0.00067 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KII92346.1 - 0.0008 18.3 1.4 0.009 14.8 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KII92346.1 - 0.00084 19.2 0.0 0.0038 17.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII92346.1 - 0.0011 17.5 0.0 0.0052 15.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 KII92346.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_22 PF13401.1 KII92347.1 - 4.7e-09 36.4 0.0 8.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII92347.1 - 5e-08 33.1 0.0 6.9e-07 29.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KII92347.1 - 3.3e-06 27.3 0.0 6.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KII92347.1 - 0.00069 19.3 0.0 0.0033 17.1 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 KII92347.1 - 0.0028 16.3 0.0 0.26 9.8 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KII92347.1 - 0.0082 15.8 0.0 0.024 14.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain cobW PF02492.14 KII92347.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KII92347.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 KII92347.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 KII92347.1 - 0.29 9.8 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.17 KII92347.1 - 0.34 9.7 0.0 0.54 9.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TP6A_N PF04406.9 KII92348.1 - 9.3e-16 57.2 0.1 1.7e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 KII92348.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Mito_carr PF00153.22 KII92349.1 - 4.7e-61 202.5 1.2 3.6e-26 90.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Homez PF11569.3 KII92349.1 - 0.17 11.0 0.1 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MSP1_C PF07462.6 KII92350.1 - 0.65 8.3 1.6 0.86 7.9 1.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ARL6IP6 PF15062.1 KII92352.1 - 0.11 12.4 1.6 0.24 11.3 1.1 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF1183 PF06682.7 KII92353.1 - 0.013 15.1 0.3 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) G8 PF10162.4 KII92353.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 G8 domain DUF1191 PF06697.7 KII92353.1 - 0.078 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 KII92353.1 - 0.41 10.7 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RhoGAP PF00620.22 KII92354.1 - 5.9e-30 103.8 0.0 1.3e-29 102.7 0.0 1.5 1 1 0 1 1 1 1 RhoGAP domain Glyco_hydro_63 PF03200.11 KII92355.1 - 5e-06 24.6 5.7 5.6e-05 21.2 0.7 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Glyco_hydro_28 PF00295.12 KII92356.1 - 1.3e-54 185.3 15.4 1.6e-54 185.1 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KII92356.1 - 1.8e-06 27.7 25.9 1.8e-06 27.7 17.9 2.2 2 0 0 2 2 2 1 Right handed beta helix region RhoGEF PF00621.15 KII92357.1 - 7.1e-38 130.2 2.1 1.2e-37 129.5 1.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KII92357.1 - 3e-34 117.6 0.1 9.5e-34 116.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.19 KII92357.1 - 6.1e-17 61.0 0.0 1.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 KII92357.1 - 5.7e-14 51.9 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PH PF00169.24 KII92357.1 - 0.0016 18.6 0.0 0.005 17.0 0.0 1.8 1 1 0 1 1 1 1 PH domain DUF4482 PF14818.1 KII92357.1 - 0.08 13.5 1.5 0.18 12.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) SPT16 PF08644.6 KII92357.1 - 0.11 12.2 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Rap1-DNA-bind PF09197.5 KII92360.1 - 3.6e-05 24.2 6.9 0.33 11.5 0.8 3.6 2 1 1 3 3 3 3 Rap1, DNA-binding HK PF02110.10 KII92361.1 - 9e-72 241.1 0.1 5.5e-70 235.3 0.1 2.1 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KII92361.1 - 2.3e-54 183.2 0.0 4.9e-54 182.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 KII92361.1 - 0.00083 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M19 PF01244.16 KII92361.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) PhyH PF05721.8 KII92362.1 - 4.8e-48 163.9 0.0 5.6e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF747 PF05346.6 KII92363.1 - 4.9e-113 377.5 3.3 6.1e-113 377.2 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family SUR7 PF06687.7 KII92365.1 - 1.1e-14 54.5 10.3 1.9e-13 50.4 7.1 2.0 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 KII92365.1 - 0.00026 20.3 1.2 0.0043 16.3 0.3 2.1 2 0 0 2 2 2 1 Clc-like Claudin_2 PF13903.1 KII92365.1 - 0.016 14.9 11.8 0.054 13.1 8.4 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1656 PF07869.7 KII92365.1 - 5.5 6.8 11.4 2.4 8.0 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) GFO_IDH_MocA PF01408.17 KII92367.1 - 5.6e-19 68.8 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KII92367.1 - 0.0011 19.3 0.2 0.015 15.7 0.0 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_6 PF12697.2 KII92367.1 - 0.019 14.8 0.2 0.049 13.4 0.2 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family GFO_IDH_MocA_C PF02894.12 KII92367.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain RrnaAD PF00398.15 KII92368.1 - 1.9e-19 69.7 0.0 2.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase WD40 PF00400.27 KII92369.1 - 6.9e-17 60.6 18.3 1.2e-06 28.1 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Beta_propel PF09826.4 KII92369.1 - 0.068 11.4 0.0 0.099 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta propeller domain ASL_C2 PF14698.1 KII92371.1 - 0.02 14.9 0.3 0.031 14.3 0.2 1.4 1 1 0 1 1 1 0 Argininosuccinate lyase C-terminal Ins134_P3_kin PF05770.6 KII92371.1 - 0.056 12.4 0.1 0.073 12.0 0.0 1.0 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase CPSF73-100_C PF11718.3 KII92372.1 - 1.9e-53 181.0 0.1 2.8e-53 180.4 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KII92372.1 - 1.7e-32 111.9 0.0 6.8e-32 110.0 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KII92372.1 - 2.5e-14 53.3 0.3 6.9e-14 51.9 0.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KII92372.1 - 1.3e-10 40.8 0.2 3e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KII92372.1 - 1.3e-09 37.8 2.3 1.9e-09 37.3 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KII92372.1 - 4e-06 26.6 0.0 2.5e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Med3 PF11593.3 KII92373.1 - 0.67 9.1 23.0 1.2 8.3 15.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mcm10 PF09332.6 KII92373.1 - 0.97 8.7 9.4 1.3 8.3 6.5 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Peptidase_S64 PF08192.6 KII92373.1 - 9.9 4.3 7.9 12 4.0 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_76 PF03663.9 KII92374.1 - 2.4e-38 132.4 23.7 3e-38 132.1 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 KII92374.1 - 0.011 15.0 1.6 0.27 10.4 0.0 2.8 2 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Sec7 PF01369.15 KII92375.1 - 1.6e-35 122.5 0.0 3.6e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KII92375.1 - 1e-26 93.4 0.0 2.2e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 KII92375.1 - 0.0015 18.6 2.2 0.0043 17.1 1.5 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 GATA PF00320.22 KII92376.1 - 5.6e-19 67.1 2.6 1.2e-18 66.1 1.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KII92376.1 - 2e-13 49.6 1.9 4.1e-13 48.6 1.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Peptidase_A22B PF04258.8 KII92377.1 - 1.6e-63 214.9 3.5 2.2e-63 214.5 2.4 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KII92377.1 - 6.8e-07 28.7 4.1 6.8e-07 28.7 2.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) Cellulase PF00150.13 KII92378.1 - 7.6e-29 100.7 3.6 1e-28 100.3 2.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KII92378.1 - 0.0088 14.9 0.0 0.05 12.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KII92378.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like G_glu_transpept PF01019.16 KII92379.1 - 4e-164 546.8 0.0 4.6e-164 546.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Keratin PF02422.11 KII92381.1 - 0.033 14.1 0.4 0.057 13.3 0.3 1.3 1 0 0 1 1 1 0 Keratin ABM PF03992.11 KII92381.1 - 0.068 13.2 0.1 0.62 10.1 0.0 2.2 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase TIP49 PF06068.8 KII92384.1 - 4.3e-174 578.8 0.0 5e-174 578.6 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KII92384.1 - 8.2e-10 38.9 0.1 2.1e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KII92384.1 - 3.6e-09 36.0 0.2 7.7e-07 28.3 0.0 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KII92384.1 - 1.6e-07 31.5 0.0 1.1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII92384.1 - 6.9e-06 26.2 0.2 0.037 14.1 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 KII92384.1 - 9.3e-06 25.4 0.1 0.0043 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KII92384.1 - 0.00054 19.6 0.2 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KII92384.1 - 0.0014 18.5 0.1 0.0036 17.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII92384.1 - 0.0037 16.7 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII92384.1 - 0.0092 15.8 0.0 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KII92384.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KII92384.1 - 0.02 14.7 0.0 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KII92384.1 - 0.031 13.4 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KII92384.1 - 0.045 14.5 0.1 0.11 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KII92384.1 - 0.046 13.2 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KII92384.1 - 0.051 12.6 0.6 0.083 11.9 0.1 1.5 2 0 0 2 2 2 0 Zeta toxin DUF2584 PF10763.4 KII92384.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) DUF2075 PF09848.4 KII92384.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KII92384.1 - 0.46 9.6 3.7 0.43 9.7 0.1 2.6 4 0 0 4 4 3 0 PhoH-like protein Oxidored_q6 PF01058.17 KII92386.1 - 2.1e-22 79.1 0.1 3.2e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F-box PF00646.28 KII92387.1 - 3.6e-08 32.8 0.0 5.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII92387.1 - 4.2e-07 29.5 0.1 6.4e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 KII92389.1 - 2.5e-51 174.3 0.0 2.3e-36 125.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII92389.1 - 1.2e-20 73.7 0.0 1e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII92389.1 - 5.5e-05 23.0 0.1 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII92389.1 - 0.00016 20.7 0.0 0.00077 18.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KII92389.1 - 0.034 13.2 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.20 KII92390.1 - 3.2e-17 62.7 0.0 7.5e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Inhibitor_I9 PF05922.11 KII92391.1 - 6.5e-08 33.0 0.0 8.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 NUDIX PF00293.23 KII92393.1 - 5.6e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain AA_permease_2 PF13520.1 KII92394.1 - 2.4e-46 158.1 41.6 2.9e-46 157.8 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII92394.1 - 1.6e-10 39.9 39.3 2.2e-10 39.4 27.2 1.2 1 0 0 1 1 1 1 Amino acid permease SLAC1 PF03595.12 KII92396.1 - 2e-74 250.2 42.8 2.3e-74 250.0 29.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel adh_short PF00106.20 KII92397.1 - 9.3e-21 74.4 0.2 1.7e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII92397.1 - 2.3e-10 40.4 0.1 3.3e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII92397.1 - 1.8e-05 24.6 0.0 0.0001 22.1 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII92397.1 - 2e-05 24.6 0.2 5.1e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KII92397.1 - 0.00013 22.1 0.0 0.0003 20.9 0.1 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KII92397.1 - 0.00015 20.9 0.1 0.00034 19.7 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KII92397.1 - 0.001 18.5 0.2 0.0023 17.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 KII92397.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain Polysacc_synt_2 PF02719.10 KII92397.1 - 0.05 12.4 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 KII92397.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.7 KII92397.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein RRM_6 PF14259.1 KII92399.1 - 3.4e-11 42.9 0.1 2.9e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII92399.1 - 5.7e-11 41.8 0.1 0.00046 19.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII92399.1 - 8.7e-05 22.2 0.0 0.0021 17.8 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4604 PF15377.1 KII92399.1 - 0.028 14.6 4.5 0.077 13.2 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) PI3_PI4_kinase PF00454.22 KII92400.1 - 1.4e-31 109.7 0.0 2.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1499 PF07386.6 KII92400.1 - 0.074 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) Mnd1 PF03962.10 KII92401.1 - 8.8e-58 195.0 0.0 9.9e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Mnd1 family MscS_porin PF12795.2 KII92401.1 - 0.00064 19.1 3.2 0.00095 18.5 2.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DNA_Packaging PF11053.3 KII92401.1 - 0.0078 15.8 0.1 0.011 15.3 0.1 1.4 1 1 0 1 1 1 1 Terminase DNA packaging enzyme FUR PF01475.14 KII92401.1 - 0.055 13.3 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family SMK-1 PF04802.10 KII92401.1 - 0.066 12.7 0.1 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Component of IIS longevity pathway SMK-1 DUF1409 PF07197.7 KII92401.1 - 0.12 12.4 1.3 0.24 11.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) RPN7 PF10602.4 KII92401.1 - 0.14 11.4 1.0 0.73 9.1 0.2 2.0 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Tannase PF07519.6 KII92403.1 - 6.8e-109 364.6 0.2 1.5e-108 363.5 0.1 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase zf-MYND PF01753.13 KII92404.1 - 0.019 14.8 9.5 0.045 13.6 6.6 1.6 1 0 0 1 1 1 0 MYND finger Fungal_trans PF04082.13 KII92405.1 - 9.6e-08 31.2 0.0 1.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII92405.1 - 1.2e-07 31.5 12.4 2e-07 30.7 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cut8_N PF14482.1 KII92405.1 - 0.0014 18.5 1.0 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 Cut8 proteasome-binding domain DUF4455 PF14643.1 KII92405.1 - 0.2 10.2 0.1 0.29 9.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) W2 PF02020.13 KII92406.1 - 1.1e-19 70.1 1.5 1.5e-19 69.7 0.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Choline_transpo PF04515.7 KII92408.1 - 8.3e-90 300.9 9.2 8.3e-90 300.9 6.4 1.9 1 1 1 2 2 2 1 Plasma-membrane choline transporter PP2C PF00481.16 KII92409.1 - 3.9e-66 223.0 0.1 2.1e-51 174.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KII92409.1 - 0.0043 16.7 0.2 0.021 14.5 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Amastin PF07344.6 KII92410.1 - 0.0002 21.0 3.5 0.00054 19.5 0.9 2.4 2 1 0 2 2 2 1 Amastin surface glycoprotein DUF998 PF06197.8 KII92410.1 - 0.00038 19.8 7.4 0.00038 19.8 5.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF998) PhnH PF05845.7 KII92410.1 - 0.086 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnH) Claudin_3 PF06653.6 KII92410.1 - 0.099 12.3 5.3 0.39 10.4 1.2 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF2079 PF09852.4 KII92410.1 - 0.11 11.1 1.4 0.2 10.3 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Ferric_reduct PF01794.14 KII92410.1 - 0.66 10.0 8.5 2.2 8.3 2.4 2.8 1 1 1 3 3 3 0 Ferric reductase like transmembrane component Claudin_2 PF13903.1 KII92410.1 - 0.77 9.4 8.7 0.096 12.3 2.7 1.9 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CcmD PF04995.9 KII92410.1 - 0.98 9.2 6.7 9.5 6.0 0.3 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2157 PF09925.4 KII92410.1 - 9.8 5.7 9.1 0.9 9.1 2.1 2.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) Acyltransferase PF01553.16 KII92411.1 - 7.8e-14 51.2 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Aconitase_C PF00694.14 KII92411.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Aconitase C-terminal domain NUC173 PF08161.7 KII92412.1 - 3e-36 124.6 0.0 1.5e-34 119.0 0.0 2.4 2 0 0 2 2 2 1 NUC173 domain MOR2-PAG1_C PF14225.1 KII92412.1 - 0.049 13.3 0.1 0.19 11.4 0.1 2.0 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HEAT PF02985.17 KII92412.1 - 0.079 13.0 2.3 20 5.6 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat DUF2151 PF10221.4 KII92412.1 - 0.33 9.0 0.8 0.53 8.3 0.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator MMS19_C PF12460.3 KII92412.1 - 0.93 8.1 9.9 0.47 9.1 0.7 3.7 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal PAC2 PF09754.4 KII92413.1 - 1.1e-24 87.5 0.0 2e-24 86.6 0.0 1.5 1 1 0 1 1 1 1 PAC2 family FAD_binding_3 PF01494.14 KII92414.1 - 1.2e-13 50.9 0.0 3.2e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain ETF_alpha PF00766.14 KII92415.1 - 5.2e-35 118.9 0.5 9.6e-35 118.0 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KII92415.1 - 1e-31 109.8 0.1 1.9e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_12 PF13087.1 KII92416.1 - 3.8e-34 117.8 0.0 6.7e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KII92416.1 - 1.5e-22 80.3 4.5 2e-12 47.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 KII92416.1 - 3.9e-09 36.3 0.0 9.6e-05 22.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KII92416.1 - 4.4e-07 29.5 0.1 1.3e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KII92416.1 - 0.0068 15.4 0.0 0.083 11.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TFIID_20kDa PF03847.8 KII92417.1 - 2.7e-28 98.0 0.5 4.5e-28 97.3 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KII92417.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyoxal_oxid_N PF07250.6 KII92418.1 - 2.8e-38 131.3 0.0 1.2e-36 125.9 0.0 2.9 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KII92418.1 - 7.6e-22 77.2 0.0 1.5e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KII92418.1 - 0.00015 21.4 0.1 0.17 11.7 0.0 3.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Git3 PF11710.3 KII92419.1 - 7.7e-08 32.1 4.2 1.5e-07 31.2 2.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KII92419.1 - 0.007 16.1 0.6 0.02 14.6 0.4 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KII92419.1 - 0.54 9.3 8.7 0.022 13.9 1.7 1.9 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) HSP20 PF00011.16 KII92423.1 - 0.00021 21.1 0.0 0.0044 16.8 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family FAD_binding_3 PF01494.14 KII92425.1 - 8.3e-17 61.2 0.0 1.8e-10 40.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KII92425.1 - 4.4e-08 32.4 0.0 1.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII92425.1 - 5.4e-08 32.3 0.9 0.00013 21.1 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KII92425.1 - 9.3e-07 28.7 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KII92425.1 - 1e-05 24.5 0.0 2.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KII92425.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII92425.1 - 0.00025 19.6 0.0 0.0063 15.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KII92425.1 - 0.0072 16.7 0.0 0.029 14.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII92425.1 - 0.017 14.1 0.1 0.054 12.5 0.0 1.8 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.7 KII92425.1 - 0.027 13.4 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KII92425.1 - 0.065 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII92425.1 - 0.067 12.2 0.4 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase AFG1_ATPase PF03969.11 KII92426.1 - 4.5e-58 196.7 0.0 1.3e-52 178.8 0.0 3.1 2 1 1 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.1 KII92426.1 - 3.8e-06 27.0 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII92426.1 - 1.5e-05 25.1 0.0 4.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KII92426.1 - 0.0004 20.4 0.0 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_29 PF13555.1 KII92426.1 - 0.0038 16.7 0.0 0.009 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KII92426.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KII92426.1 - 0.0068 16.1 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KII92426.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KII92426.1 - 0.026 14.2 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KII92426.1 - 0.038 13.4 0.1 1.1 8.6 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KII92426.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 KII92426.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KII92426.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Pkinase PF00069.20 KII92427.1 - 1.3e-21 76.9 0.0 4.7e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92427.1 - 2.2e-13 49.8 0.0 2.5e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 KII92427.1 - 0.0037 16.6 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family RTC4 PF14474.1 KII92429.1 - 2.3e-06 27.5 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain SynMuv_product PF06047.6 KII92430.1 - 5.6e-43 144.9 3.4 5.6e-43 144.9 2.3 2.4 2 0 0 2 2 2 1 Ras-induced vulval development antagonist FKBP_C PF00254.23 KII92431.1 - 3.7e-31 107.0 0.0 4.5e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L39 PF00832.15 KII92432.1 - 1e-22 79.3 9.2 1.2e-22 79.1 6.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein CHD5 PF04420.9 KII92433.1 - 7.3e-41 139.5 0.8 9.1e-41 139.1 0.6 1.1 1 0 0 1 1 1 1 CHD5-like protein Vps8 PF12816.2 KII92434.1 - 3.5e-69 232.0 0.0 7e-66 221.2 0.0 2.4 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KII92434.1 - 0.0052 16.3 0.0 0.26 10.8 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Rick_17kDa_Anti PF05433.10 KII92434.1 - 0.33 10.6 0.8 0.67 9.6 0.5 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Daxx PF03344.10 KII92434.1 - 4.1 5.7 7.7 6.2 5.1 5.4 1.1 1 0 0 1 1 1 0 Daxx Family COG2 PF06148.6 KII92438.1 - 8.1e-27 93.7 0.5 2e-26 92.4 0.3 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 KII92438.1 - 2.4e-16 59.9 0.0 4.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) PHD PF00628.24 KII92439.1 - 1.6e-10 40.5 8.7 2.6e-10 39.8 6.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 KII92439.1 - 0.085 12.5 1.8 0.18 11.5 1.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.1 KII92439.1 - 0.49 9.7 4.2 0.9 8.9 2.9 1.4 1 0 0 1 1 1 0 PHD-finger PALP PF00291.20 KII92440.1 - 2.4e-76 256.8 0.1 2.9e-76 256.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KII92440.1 - 2.3e-41 139.2 0.0 2.4e-26 91.1 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase NDUF_B12 PF08122.7 KII92441.1 - 1.6e-19 69.3 2.1 1.7e-19 69.2 1.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I_N PF02919.10 KII92442.1 - 2.8e-97 324.2 0.9 2.8e-97 324.2 0.6 3.5 3 2 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KII92442.1 - 4.7e-86 287.7 5.8 4.7e-86 287.7 4.0 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KII92442.1 - 3.3e-31 106.7 0.2 9.9e-31 105.2 0.1 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KII92442.1 - 0.032 13.3 0.0 0.095 11.8 0.0 1.8 1 0 0 1 1 1 0 RolB/RolC glucosidase family CTP_transf_1 PF01148.15 KII92443.1 - 5.5e-76 255.6 22.8 7.2e-76 255.2 15.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosom_S12_S23 PF00164.20 KII92444.1 - 1.3e-39 134.4 1.1 1.5e-39 134.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.15 KII92445.1 - 6e-09 35.8 0.0 1.1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII92445.1 - 1.5e-07 31.5 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family C2 PF00168.25 KII92446.1 - 5.2e-11 42.2 0.0 1.4e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain WD40 PF00400.27 KII92446.1 - 1.4e-09 37.4 19.7 0.022 14.6 0.1 7.9 9 0 0 9 9 9 3 WD domain, G-beta repeat NACHT PF05729.7 KII92446.1 - 1.2e-06 28.2 0.0 3.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KII92446.1 - 3.4e-06 27.1 0.0 9.2e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KII92446.1 - 0.0023 16.8 0.0 0.0052 15.6 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain PQQ_2 PF13360.1 KII92446.1 - 0.0033 16.9 1.6 2 7.8 0.1 2.9 2 1 0 2 2 2 2 PQQ-like domain AAA_17 PF13207.1 KII92446.1 - 0.036 14.8 0.0 0.089 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KII92446.1 - 0.19 11.8 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pox_A6 PF04924.7 KII92446.1 - 0.2 10.4 0.2 0.31 9.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein Arch_ATPase PF01637.13 KII92446.1 - 0.26 10.9 0.0 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 KII92446.1 - 0.27 11.5 0.0 0.58 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain EMP70 PF02990.11 KII92448.1 - 3.5e-183 609.8 0.0 5.4e-183 609.1 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 tRNA-synt_1b PF00579.20 KII92449.1 - 1.4e-72 244.2 0.0 1.8e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 KII92449.1 - 9.8e-08 31.3 0.0 4.3e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 S4 domain TGT PF01702.13 KII92450.1 - 1e-82 277.0 0.0 1.3e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.24 KII92451.1 - 3.7e-36 124.1 0.0 1.2e-35 122.5 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII92451.1 - 7.5e-21 73.7 0.6 2.3e-20 72.2 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KII92451.1 - 8.8e-20 70.2 4.6 8.8e-20 70.2 3.2 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Pkinase PF00069.20 KII92452.1 - 0.001 18.2 0.1 0.0046 16.1 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92452.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 KII92452.1 - 0.02 14.6 0.1 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_A_bac PF01000.21 KII92453.1 - 5.4e-29 100.6 0.0 9.9e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KII92453.1 - 5.3e-15 54.2 0.0 7.6e-15 53.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 KII92453.1 - 0.033 13.6 0.1 0.088 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF22 Methyltransf_2 PF00891.13 KII92454.1 - 8.7e-30 103.6 0.0 3.9e-29 101.5 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase PFK PF00365.15 KII92454.1 - 0.096 11.6 0.0 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Phosphofructokinase Methyltransf_2 PF00891.13 KII92455.1 - 1.8e-26 92.8 0.0 3.3e-26 91.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII92455.1 - 0.00013 22.4 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KII92455.1 - 0.00087 19.0 0.1 0.0032 17.2 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.1 KII92455.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF2868 PF11067.3 KII92455.1 - 0.037 13.1 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MTS PF05175.9 KII92455.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.10 KII92455.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 KII92455.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 KII92456.1 - 1.4e-32 111.9 0.2 2.2e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII92456.1 - 8.5e-16 59.0 0.0 1.7e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII92456.1 - 1e-08 34.9 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KII92456.1 - 0.082 12.4 0.4 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HECT PF00632.20 KII92457.1 - 2e-91 306.4 0.0 3.3e-91 305.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 KII92457.1 - 2.4e-77 260.2 4.8 5.1e-77 259.1 0.0 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KII92457.1 - 3.1e-66 223.9 1.4 5.9e-66 223.0 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KII92457.1 - 4.7e-29 100.4 5.1 7.3e-28 96.6 4.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 KII92457.1 - 1e-08 34.7 0.0 3.1e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain PC4 PF02229.11 KII92458.1 - 1.1e-23 82.1 0.4 1.1e-23 82.1 0.3 1.8 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) DTHCT PF08070.6 KII92458.1 - 0.039 14.6 19.2 0.86 10.3 7.9 2.4 1 1 1 2 2 2 0 DTHCT (NUC029) region DUF3332 PF11810.3 KII92458.1 - 0.049 13.2 1.9 0.064 12.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) TFIIF_alpha PF05793.7 KII92458.1 - 2.5 6.3 22.4 0.53 8.6 13.3 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.9 KII92458.1 - 3.3 7.2 14.4 4.9 6.6 10.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec62 PF03839.11 KII92458.1 - 6.6 6.0 9.1 9.5 5.5 6.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ABC1 PF03109.11 KII92459.1 - 8.1e-32 109.7 0.0 1.3e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KII92459.1 - 0.024 13.9 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KII92459.1 - 0.22 10.6 0.0 0.59 9.2 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain HSP9_HSP12 PF04119.7 KII92460.1 - 2.7e-20 72.2 2.4 3.9e-20 71.6 1.6 1.3 1 0 0 1 1 1 1 Heat shock protein 9/12 zf-RING_2 PF13639.1 KII92461.1 - 1.8e-12 46.8 4.7 2.8e-12 46.2 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII92461.1 - 7.1e-07 29.2 1.6 1.3e-06 28.4 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KII92461.1 - 1e-06 28.4 1.3 1.8e-06 27.7 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KII92461.1 - 1.6e-05 24.5 2.2 2.5e-05 23.8 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII92461.1 - 6.4e-05 22.8 4.3 0.00011 22.1 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII92461.1 - 6.9e-05 22.3 3.0 0.00011 21.7 2.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KII92461.1 - 7.9e-05 22.2 2.9 0.00013 21.5 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII92461.1 - 0.00021 20.9 0.8 0.00035 20.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KII92461.1 - 0.005 16.7 1.9 0.011 15.6 1.3 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KII92461.1 - 0.038 14.0 2.8 0.067 13.2 2.0 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.1 KII92461.1 - 1.3 8.5 3.8 8.3 6.0 0.3 2.4 1 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 KII92461.1 - 3 7.4 8.1 11 5.6 5.6 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger HTH_21 PF13276.1 KII92463.1 - 0.014 15.4 0.0 0.76 9.8 0.0 2.4 1 1 1 2 2 2 0 HTH-like domain HTH_32 PF13565.1 KII92463.1 - 0.046 14.5 0.6 2.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain Alpha_kinase PF02816.13 KII92464.1 - 2.2e-15 56.8 0.0 2.7e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Aminotran_3 PF00202.16 KII92465.1 - 7.8e-104 347.1 0.0 9.2e-104 346.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Alba PF01918.16 KII92465.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Alba Aminotran_1_2 PF00155.16 KII92465.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Amidohydro_1 PF01979.15 KII92466.1 - 1.4e-26 93.9 0.0 5.4e-26 92.0 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KII92466.1 - 4.4e-22 79.4 1.4 6.6e-10 39.4 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KII92466.1 - 1.7e-11 43.7 1.0 4.5e-11 42.4 0.7 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KII92466.1 - 6.6e-09 35.4 0.2 2.3e-05 23.7 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Yippee-Mis18 PF03226.9 KII92467.1 - 1.5e-10 40.9 0.1 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 KII92467.1 - 0.087 12.5 0.0 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RIG-I_C-RD PF11648.3 KII92467.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I RabGAP-TBC PF00566.13 KII92468.1 - 2.1e-52 177.6 0.2 3.7e-52 176.9 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TMF_DNA_bd PF12329.3 KII92468.1 - 0.0064 16.2 0.8 0.0064 16.2 0.6 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 KII92468.1 - 2.9 7.9 9.1 0.28 11.2 1.7 2.6 3 0 0 3 3 3 0 DivIVA protein DivIC PF04977.10 KII92468.1 - 4.9 6.7 9.4 0.099 12.1 0.5 2.6 2 1 1 3 3 3 0 Septum formation initiator Cauli_VI PF01693.11 KII92469.1 - 0.0057 16.6 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin ATG27 PF09451.5 KII92470.1 - 1.9e-49 168.3 0.0 2.2e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 KII92470.1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KII92470.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Josephin PF02099.12 KII92471.1 - 1.9e-51 173.8 0.3 2.9e-51 173.2 0.2 1.3 1 0 0 1 1 1 1 Josephin Acetyltransf_1 PF00583.19 KII92472.1 - 1.4e-10 41.0 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII92472.1 - 2e-08 34.2 0.0 4.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII92472.1 - 8.7e-07 29.0 0.0 2.3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII92472.1 - 0.0002 21.1 0.1 0.0006 19.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII92472.1 - 0.047 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 KII92472.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DASH_Duo1 PF08651.5 KII92473.1 - 5.4e-12 45.1 0.5 8.4e-12 44.4 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Atrophin-1 PF03154.10 KII92473.1 - 0.051 11.7 10.6 0.095 10.8 7.3 1.5 1 0 0 1 1 1 0 Atrophin-1 family DUF572 PF04502.8 KII92473.1 - 0.39 9.8 12.2 0.55 9.3 8.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mannosyl_trans2 PF04188.8 KII92474.1 - 1.6e-53 182.2 16.3 2e-53 181.8 11.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Sigma_reg_N PF13800.1 KII92474.1 - 0.26 11.3 0.8 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal LRR_4 PF12799.2 KII92475.1 - 0.00079 18.9 4.3 30 4.3 0.0 6.5 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) TFIIS_C PF01096.13 KII92476.1 - 2.3e-18 65.5 1.4 2.3e-18 65.5 0.9 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) PhnA_Zn_Ribbon PF08274.7 KII92476.1 - 2.3e-06 27.2 7.7 0.03 14.0 2.8 3.0 2 2 1 3 3 3 2 PhnA Zinc-Ribbon RNA_POL_M_15KD PF02150.11 KII92476.1 - 2.6e-06 27.0 0.8 2.6e-06 27.0 0.6 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.3 KII92476.1 - 4.4e-05 22.7 0.9 4.4e-05 22.7 0.6 2.5 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 KII92476.1 - 0.0006 19.5 7.5 0.003 17.3 0.2 2.7 2 1 0 2 2 2 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KII92476.1 - 0.00091 18.9 10.3 0.004 16.9 0.8 3.0 2 1 1 3 3 3 1 Transposase zinc-ribbon domain UPF0547 PF10571.4 KII92476.1 - 0.00097 18.7 8.3 0.036 13.7 0.2 2.8 2 1 0 2 2 2 1 Uncharacterised protein family UPF0547 DUF2387 PF09526.5 KII92476.1 - 0.0011 18.8 5.5 0.1 12.5 0.4 2.4 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) DNA_RNApol_7kD PF03604.8 KII92476.1 - 0.013 15.0 8.8 0.29 10.6 0.5 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 KII92476.1 - 0.015 14.6 9.4 1.2 8.5 0.0 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 KII92476.1 - 0.02 14.8 10.5 0.43 10.5 0.1 4.0 3 1 1 4 4 4 0 Zinc ribbon domain IBR PF01485.16 KII92476.1 - 0.024 14.4 8.3 0.28 11.0 0.2 2.5 2 1 0 2 2 2 0 IBR domain DUF2296 PF10058.4 KII92476.1 - 0.059 13.1 4.6 9 6.1 0.1 3.8 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) Lar_restr_allev PF14354.1 KII92476.1 - 0.062 13.6 8.7 0.18 12.1 0.6 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 KII92476.1 - 0.081 12.5 8.6 1.2 8.8 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 KII92476.1 - 0.082 12.4 12.5 0.14 11.7 1.0 3.0 3 1 0 3 3 2 0 zinc-ribbon domain PHD PF00628.24 KII92476.1 - 0.087 12.5 9.3 1.3 8.7 0.7 2.8 2 1 0 2 2 2 0 PHD-finger Cys_rich_CPCC PF14206.1 KII92476.1 - 0.091 12.3 0.9 0.54 9.8 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-RING_3 PF14369.1 KII92476.1 - 0.18 11.8 9.0 8.5 6.4 0.1 4.0 3 1 1 4 4 4 0 zinc-finger Ribosomal_S27e PF01667.12 KII92476.1 - 0.35 10.4 7.0 5.9 6.5 0.6 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 zf-tcix PF14952.1 KII92476.1 - 0.38 10.1 3.9 14 5.0 0.0 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding HypA PF01155.14 KII92476.1 - 0.38 10.4 7.1 0.79 9.4 0.2 2.6 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 KII92476.1 - 0.38 10.0 14.3 0.5 9.6 0.3 3.2 3 1 0 4 4 3 0 zinc-ribbon domain zf-UBR PF02207.15 KII92476.1 - 0.38 10.4 8.6 0.37 10.5 0.4 2.9 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-C4_Topoisom PF01396.14 KII92476.1 - 0.41 10.1 7.5 1.7 8.2 0.2 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Cytochrom_CIII PF02085.11 KII92476.1 - 0.49 10.5 9.1 2 8.5 6.6 1.8 1 1 0 1 1 1 0 Class III cytochrome C family A2L_zn_ribbon PF08792.5 KII92476.1 - 0.6 9.6 10.1 2.2 7.8 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain DNA_ligase_ZBD PF03119.11 KII92476.1 - 0.61 9.8 8.1 5.3 6.8 0.5 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF164 PF02591.10 KII92476.1 - 0.79 9.5 7.3 12 5.8 0.0 3.5 4 0 0 4 4 3 0 Putative zinc ribbon domain Zn_ribbon_recom PF13408.1 KII92476.1 - 0.98 9.7 7.3 10 6.4 0.4 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.7 KII92476.1 - 1.2 8.9 9.4 1.1 9.0 0.5 2.8 2 1 0 2 2 2 0 zinc-ribbons GFA PF04828.9 KII92476.1 - 1.7 8.6 7.8 1.2 9.1 0.4 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C4pol PF14260.1 KII92476.1 - 2.3 8.2 6.3 1.3 9.0 0.9 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zinc_ribbon_5 PF13719.1 KII92476.1 - 3 7.5 10.5 27 4.4 0.8 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 KII92476.1 - 3.7 7.0 8.3 2.4 7.7 0.2 2.8 1 1 2 3 3 3 0 Transposase zinc-binding domain DUF1451 PF07295.6 KII92476.1 - 4.4 7.0 10.3 7.5 6.3 1.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1451) PADR1 PF08063.7 KII92476.1 - 5.4 6.4 9.2 3 7.3 0.1 3.3 3 1 1 4 4 4 0 PADR1 (NUC008) domain zf-CHY PF05495.7 KII92476.1 - 7.3 6.8 11.0 2.8 8.1 1.1 3.1 2 2 0 2 2 2 0 CHY zinc finger DUF563 PF04577.9 KII92478.1 - 1.2e-15 58.0 0.1 2.5e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF3421 PF11901.3 KII92479.1 - 8.4e-27 93.2 0.3 6.9e-21 74.1 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 KII92479.1 - 0.00028 20.3 2.4 0.00028 20.3 1.7 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain PAT1 PF09770.4 KII92479.1 - 0.055 11.7 3.6 0.063 11.5 2.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cellulase PF00150.13 KII92481.1 - 1.1e-28 100.2 2.1 1.4e-28 99.8 1.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KII92481.1 - 4.2e-14 51.8 5.2 4.2e-14 51.8 3.6 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 KII92481.1 - 0.0014 17.6 0.0 0.0083 15.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KII92481.1 - 0.0098 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydr_30_2 PF14587.1 KII92482.1 - 2e-20 73.0 6.1 4.1e-20 72.0 4.2 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_transf_49 PF13896.1 KII92483.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Palm_thioest PF02089.10 KII92487.1 - 1.2e-56 191.7 0.0 1.5e-49 168.4 0.0 2.1 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 KII92487.1 - 0.0027 17.3 0.0 0.0065 16.0 0.0 1.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold CsbD PF05532.7 KII92488.1 - 9.4e-13 47.6 18.5 3.4e-09 36.2 2.7 2.3 1 1 1 2 2 2 2 CsbD-like Nucleos_tra2_C PF07662.8 KII92489.1 - 1.1e-63 214.5 8.1 1.1e-63 214.5 5.6 1.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KII92489.1 - 1.7e-16 60.3 4.0 1.7e-16 60.3 2.8 3.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KII92489.1 - 0.00092 19.0 5.2 0.00092 19.0 3.6 2.4 2 0 0 2 2 2 1 Nucleoside recognition WD40 PF00400.27 KII92490.1 - 7.9e-19 66.7 4.4 3.1e-06 26.8 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Sugar_tr PF00083.19 KII92491.1 - 2.4e-90 303.3 25.2 2.8e-90 303.0 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII92491.1 - 1.2e-17 63.7 42.9 2.1e-14 53.0 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII92492.1 - 3.6e-89 299.4 26.1 4.5e-89 299.0 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII92492.1 - 1.4e-18 66.7 44.8 4.8e-12 45.2 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPA_interact_C PF14768.1 KII92493.1 - 0.067 13.5 0.2 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Gly-zipper_OmpA PF13436.1 KII92494.1 - 0.91 9.2 7.8 1.6 8.4 5.4 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain MPC PF03650.8 KII92496.1 - 9.9e-33 112.6 0.1 1.5e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MPC PF03650.8 KII92497.1 - 2.1e-36 124.5 1.4 1.5e-18 66.8 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0041) zf-C2H2 PF00096.21 KII92498.1 - 1.6 9.2 5.7 9.3 6.8 0.1 3.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 KII92498.1 - 1.7 8.6 4.9 1.1 9.2 1.5 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-DNA_Pol PF08996.5 KII92498.1 - 4.2 6.6 5.9 0.33 10.2 0.4 1.8 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DASH_Dad4 PF08650.5 KII92499.1 - 4.5e-15 55.3 1.5 5e-15 55.1 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 UPF0203 PF05254.7 KII92499.1 - 0.013 15.3 0.5 0.07 12.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) WASH-7_mid PF14744.1 KII92499.1 - 0.065 12.0 0.5 0.07 11.9 0.3 1.0 1 0 0 1 1 1 0 WASH complex subunit 7 DUF922 PF06037.6 KII92499.1 - 0.09 12.0 0.8 0.11 11.8 0.6 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Sugar_tr PF00083.19 KII92502.1 - 1.4e-84 284.3 26.5 1.6e-84 284.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII92502.1 - 1.5e-33 116.0 42.3 1.5e-25 89.6 14.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KII92502.1 - 6.8e-05 21.1 3.3 0.082 11.0 0.4 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Toxin_5 PF05294.8 KII92503.1 - 0.28 11.4 7.1 0.5 10.6 5.0 1.4 1 0 0 1 1 1 0 Scorpion short toxin Peptidase_M24 PF00557.19 KII92504.1 - 3.4e-41 141.1 0.0 4.6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KII92504.1 - 4.4e-10 40.1 0.1 2.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain NOG1 PF06858.9 KII92505.1 - 1.1e-27 95.5 0.1 2.3e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 KII92505.1 - 2.1e-27 94.5 2.1 2.3e-27 94.4 0.2 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 KII92505.1 - 1.1e-16 60.7 0.0 2.9e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII92505.1 - 1.3e-10 40.8 0.0 2.9e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KII92505.1 - 0.0031 17.9 0.0 0.0086 16.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KII92505.1 - 0.005 16.0 0.0 0.047 12.8 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 DUF3591 PF12157.3 KII92505.1 - 0.027 12.9 2.9 0.044 12.1 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3591) Dynamin_N PF00350.18 KII92505.1 - 0.032 14.0 1.5 2.7 7.8 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.11 KII92505.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 KII92505.1 - 0.073 12.7 0.1 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KII92506.1 - 2.9e-109 365.3 0.0 3.3e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII92506.1 - 6.2e-10 38.5 0.4 5.1e-06 25.8 0.0 2.9 2 1 1 3 3 3 2 ADP-ribosylation factor family NACHT PF05729.7 KII92506.1 - 0.0072 16.0 0.0 1 8.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Gtr1_RagA PF04670.7 KII92506.1 - 0.037 13.1 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DAP3 PF10236.4 KII92506.1 - 0.062 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 KII92506.1 - 0.064 12.7 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF1403 PF07183.6 KII92507.1 - 0.019 14.3 0.6 0.023 14.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) IBR PF01485.16 KII92508.1 - 5.9e-11 42.0 36.7 1.3e-07 31.4 8.6 3.3 3 0 0 3 3 3 3 IBR domain DUF2029 PF09594.5 KII92509.1 - 0.0042 16.6 0.2 0.0053 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) Macoilin PF09726.4 KII92510.1 - 1.8 6.7 7.1 2.8 6.1 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Glyoxalase PF00903.20 KII92513.1 - 3.5e-24 85.2 0.1 4.1e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KII92513.1 - 2.9e-16 60.0 0.1 3.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KII92513.1 - 1.5e-07 31.3 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KII92513.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Nop14 PF04147.7 KII92513.1 - 0.078 10.8 0.1 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family EAP30 PF04157.11 KII92513.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family CppA_N PF14506.1 KII92513.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal F-box-like PF12937.2 KII92516.1 - 0.0052 16.4 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 F-box-like Tim17 PF02466.14 KII92517.1 - 1.4e-30 106.0 6.0 1.6e-30 105.7 4.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.2 KII92521.1 - 3.2e-05 23.5 0.0 7.9e-05 22.3 0.0 1.7 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII92522.1 - 3.2e-05 23.5 0.0 7.9e-05 22.3 0.0 1.7 2 1 0 2 2 2 1 F-box-like zf-4CXXC_R1 PF10497.4 KII92523.1 - 4.1e-16 59.0 18.0 7.1e-15 55.0 12.5 2.3 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF4337 PF14235.1 KII92523.1 - 6.8 6.5 9.4 0.22 11.3 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) R3H PF01424.17 KII92524.1 - 0.064 12.9 0.5 0.17 11.5 0.4 1.7 1 0 0 1 1 1 0 R3H domain F-box-like PF12937.2 KII92525.1 - 0.00039 20.0 1.1 0.00039 20.0 0.7 1.9 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 KII92526.1 - 4.5e-14 51.9 40.2 2.3e-13 49.5 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KII92526.1 - 0.21 11.3 5.1 0.18 11.6 0.3 2.9 3 0 0 3 3 3 0 MFS_1 like family F-box-like PF12937.2 KII92527.1 - 3.7e-08 32.9 0.5 2.2e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 F-box-like DMPK_coil PF08826.5 KII92527.1 - 0.061 13.2 0.2 0.094 12.6 0.2 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like UPF0061 PF02696.9 KII92528.1 - 1.6e-97 326.8 0.0 2e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family F-box-like PF12937.2 KII92529.1 - 1.1e-09 37.8 0.3 1.1e-08 34.6 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII92530.1 - 6.6e-11 41.7 0.5 2.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII92530.1 - 0.0089 15.6 0.1 0.048 13.3 0.0 2.2 1 1 0 1 1 1 1 F-box domain Striatin PF08232.7 KII92530.1 - 0.035 14.4 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Striatin family zf-U1 PF06220.7 KII92531.1 - 8.3e-11 41.2 2.8 1.3e-10 40.6 1.9 1.3 1 0 0 1 1 1 1 U1 zinc finger Methyltransf_26 PF13659.1 KII92532.1 - 9.7e-13 48.1 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KII92532.1 - 1.9e-11 43.8 0.0 2.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 KII92532.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 KII92532.1 - 0.071 12.5 0.0 0.71 9.3 0.0 2.2 2 1 0 2 2 2 0 DNA methylase SWIM PF04434.12 KII92533.1 - 6e-06 25.6 0.1 1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Chitin_synth_1 PF01644.12 KII92534.1 - 5.1e-71 237.7 0.0 2.6e-70 235.4 0.0 2.1 1 1 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KII92534.1 - 3.1e-24 84.4 0.0 6.3e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KII92534.1 - 1.4e-23 83.1 11.8 1e-17 63.7 0.5 2.8 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KII92534.1 - 6.2e-08 32.7 0.0 1.5e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KII92534.1 - 8.4e-08 32.1 5.9 4.4e-07 29.7 4.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 IncA PF04156.9 KII92534.1 - 0.077 12.5 5.8 0.15 11.6 4.0 1.5 1 0 0 1 1 1 0 IncA protein F-box-like PF12937.2 KII92535.1 - 5.5e-11 42.0 0.0 1.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII92535.1 - 7.3e-05 22.3 0.0 0.00037 20.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain Striatin PF08232.7 KII92535.1 - 0.02 15.2 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Striatin family TPP1 PF10341.4 KII92536.1 - 9.6e-12 44.8 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD SIR2 PF02146.12 KII92537.1 - 1.8e-33 115.7 0.0 8.4e-33 113.5 0.0 2.0 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KII92537.1 - 0.012 15.4 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PALP PF00291.20 KII92538.1 - 2.2e-60 204.5 0.2 2.5e-60 204.3 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 KII92539.1 - 1.3e-77 258.9 0.0 1.5e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KII92539.1 - 3.5e-13 49.2 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KII92539.1 - 9.2e-12 44.5 0.0 1.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KII92539.1 - 1.2e-11 43.9 1.0 1e-07 31.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KII92539.1 - 7.8e-10 38.2 0.0 9.3e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KII92539.1 - 1.4e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KII92539.1 - 0.00013 21.8 0.1 0.00033 20.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KII92539.1 - 0.012 15.0 0.0 0.041 13.3 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KII92539.1 - 0.014 14.5 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase L27 PF02828.11 KII92539.1 - 0.015 15.0 0.6 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 L27 domain LRR_8 PF13855.1 KII92540.1 - 3.1e-15 55.6 8.7 5.4e-10 38.8 2.3 3.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 KII92540.1 - 5.7e-15 54.5 10.5 2.1e-05 24.0 0.2 4.8 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII92540.1 - 1.9e-07 30.1 10.8 0.18 11.9 0.1 6.3 4 2 2 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KII92540.1 - 0.00036 20.3 10.2 1.1 9.5 0.4 5.6 5 1 2 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 KII92540.1 - 0.065 13.4 13.7 11 6.7 0.3 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_9 PF14580.1 KII92540.1 - 0.093 12.2 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat UBA PF00627.26 KII92541.1 - 1.3e-24 85.3 1.5 4.3e-13 48.6 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 KII92541.1 - 1.5e-19 69.2 9.0 1.5e-19 69.2 6.2 1.7 2 0 0 2 2 1 1 XPC-binding domain ubiquitin PF00240.18 KII92541.1 - 7.2e-18 63.7 1.6 1.1e-17 63.1 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KII92541.1 - 7.3e-07 28.7 2.2 1.2e-06 28.1 1.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KII92541.1 - 0.01 15.4 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain WIYLD PF10440.4 KII92541.1 - 0.011 15.6 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF2407 PF10302.4 KII92541.1 - 0.018 15.1 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KII92541.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 KII92541.1 - 0.037 13.5 0.0 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 CUE domain Rap1_C PF11626.3 KII92541.1 - 0.088 12.6 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ubiquitin_2 PF14560.1 KII92541.1 - 0.1 12.8 0.3 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1296 PF06972.6 KII92541.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) MSA-2c PF12238.3 KII92541.1 - 1.3 8.6 7.6 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c TFIIA PF03153.8 KII92541.1 - 1.5 8.6 7.4 2.3 8.0 5.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PLA2_B PF01735.13 KII92542.1 - 1e-104 350.4 0.0 1.4e-104 350.0 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SKG6 PF08693.5 KII92542.1 - 0.29 10.4 3.9 0.64 9.3 2.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ADH_N PF08240.7 KII92543.1 - 7.5e-26 90.0 4.7 1.6e-25 88.9 3.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII92543.1 - 3.4e-15 55.7 0.0 5.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII92543.1 - 1.7e-06 28.9 0.0 2.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KII92543.1 - 0.00041 20.4 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Cutinase PF01083.17 KII92543.1 - 0.00044 20.0 0.1 0.0009 19.0 0.1 1.5 1 1 0 1 1 1 1 Cutinase 2-Hacid_dh_C PF02826.14 KII92543.1 - 0.0011 18.1 0.1 0.0021 17.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KII92543.1 - 0.0027 17.2 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Tetraspannin PF00335.15 KII92543.1 - 0.083 12.1 1.3 0.11 11.7 0.2 1.6 2 0 0 2 2 2 0 Tetraspanin family ADH_N PF08240.7 KII92544.1 - 4.8e-26 90.6 4.3 9.7e-26 89.6 2.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII92544.1 - 1.9e-15 56.5 0.0 3.2e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII92544.1 - 1.1e-06 29.5 0.0 1.8e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KII92544.1 - 0.00037 20.5 0.0 0.00062 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 KII92544.1 - 0.00052 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Cutinase PF01083.17 KII92544.1 - 0.00082 19.1 0.1 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 Cutinase 2-Hacid_dh_C PF02826.14 KII92544.1 - 0.0011 18.1 0.1 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tetraspannin PF00335.15 KII92544.1 - 0.053 12.7 0.7 0.095 11.9 0.2 1.6 2 0 0 2 2 2 0 Tetraspanin family GFO_IDH_MocA PF01408.17 KII92544.1 - 0.064 13.7 0.4 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_61 PF03443.9 KII92545.1 - 1.9e-62 210.9 0.2 2.2e-62 210.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.7 KII92546.1 - 9.1e-42 141.9 9.7 1.2e-41 141.5 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RNase_H2-Ydr279 PF09468.5 KII92546.1 - 0.74 8.9 4.8 0.91 8.6 3.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1191 PF06697.7 KII92547.1 - 0.0073 15.1 0.0 0.019 13.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) T2SM PF04612.7 KII92547.1 - 0.0087 15.8 0.0 0.041 13.6 0.0 2.1 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M Herpes_gE PF02480.11 KII92547.1 - 0.022 13.0 0.0 0.051 11.8 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 KII92547.1 - 0.059 12.8 0.3 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) YajC PF02699.10 KII92547.1 - 0.14 11.8 0.5 0.26 11.0 0.4 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit PgaD PF13994.1 KII92547.1 - 0.39 10.1 0.2 0.71 9.3 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein Vps53_N PF04100.7 KII92548.1 - 5.7e-83 278.8 0.0 1e-82 277.9 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 KII92548.1 - 6.3e-07 27.8 2.1 8.4e-07 27.4 0.0 2.0 2 1 1 3 3 3 1 Exocyst complex component Sec6 DUF2450 PF10475.4 KII92548.1 - 1.9e-06 27.0 4.0 4.2e-06 25.8 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF1515 PF07439.6 KII92548.1 - 1.2 8.9 6.7 0.28 10.9 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RCC1 PF00415.13 KII92549.1 - 1.1e-14 54.3 1.2 3.4e-06 27.1 0.0 3.9 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII92549.1 - 1.1e-13 50.4 5.3 6.1e-08 32.0 1.1 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 KII92550.1 - 2.3e-10 40.6 0.0 4.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII92550.1 - 7.9e-09 35.7 0.1 4.9e-07 30.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KII92550.1 - 4.9e-06 26.0 0.0 3.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KII92550.1 - 0.00012 22.1 0.0 0.00035 20.7 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII92550.1 - 0.00029 20.7 0.3 0.031 14.5 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Methyltransf_31 PF13847.1 KII92550.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KII92551.1 - 4.2e-05 22.8 0.0 0.00028 20.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain DUF1460 PF07313.7 KII92551.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) UvdE PF03851.9 KII92552.1 - 8.7e-88 293.9 0.0 1.1e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE BAR PF03114.13 KII92553.1 - 8.3e-51 172.6 1.6 9.8e-51 172.4 1.1 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KII92553.1 - 0.0015 17.9 2.0 0.04 13.2 0.2 2.1 2 0 0 2 2 2 1 Arfaptin-like domain AAA_13 PF13166.1 KII92553.1 - 0.052 12.0 0.6 0.075 11.4 0.4 1.3 1 0 0 1 1 1 0 AAA domain UPF0193 PF05250.6 KII92553.1 - 0.053 13.0 0.4 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) IncA PF04156.9 KII92553.1 - 0.056 13.0 0.5 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 IncA protein AAA_27 PF13514.1 KII92553.1 - 0.07 10.8 4.1 0.06 11.0 0.4 1.9 2 0 0 2 2 2 0 AAA domain Vps5 PF09325.5 KII92553.1 - 0.13 11.5 2.6 0.47 9.6 0.2 2.1 2 0 0 2 2 2 0 Vps5 C terminal like Metal_resist PF13801.1 KII92553.1 - 0.39 10.6 5.5 4.1 7.4 0.1 2.5 1 1 0 2 2 2 0 Heavy-metal resistance AMP-binding PF00501.23 KII92555.1 - 1.5e-46 158.6 0.0 2.2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII92555.1 - 9.1e-05 23.3 0.0 0.00019 22.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 KII92555.1 - 0.1 12.4 0.3 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family RHD3 PF05879.7 KII92556.1 - 1.9e-250 832.8 0.0 2.6e-250 832.4 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KII92556.1 - 3.1e-07 29.7 0.2 6.1e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KII92556.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KII92556.1 - 2e-05 24.5 0.0 8.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KII92556.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KII92556.1 - 0.0012 18.8 0.0 0.0039 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF3145 PF11343.3 KII92556.1 - 0.1 11.9 1.0 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Methyltransf_2 PF00891.13 KII92557.1 - 2.9e-37 128.1 0.0 4.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII92557.1 - 2.2e-07 31.4 0.0 4.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII92557.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.1 KII92559.1 - 2.9e-17 63.4 0.0 1e-16 61.6 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII92559.1 - 3.1e-09 37.5 0.0 9.8e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII92559.1 - 2e-05 24.8 0.0 2.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KII92559.1 - 0.00035 20.4 0.0 0.09 12.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII92559.1 - 0.0024 17.5 0.0 0.0079 15.8 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Glutaredoxin PF00462.19 KII92560.1 - 5.1e-13 48.8 0.0 9.3e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_6 PF12697.2 KII92560.1 - 0.061 13.1 0.0 0.61 9.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioredoxin_2 PF13098.1 KII92560.1 - 0.062 13.4 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Fungal_trans PF04082.13 KII92561.1 - 1e-29 103.2 0.1 6.5e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII92561.1 - 0.003 17.4 3.3 0.0056 16.5 2.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 KII92562.1 - 2.7e-29 101.4 4.3 2.7e-29 101.4 3.0 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KII92562.1 - 6e-07 29.2 0.0 1.8e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like BRO1 PF03097.13 KII92563.1 - 5.3e-18 64.9 0.0 7.3e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF1253 PF06862.7 KII92564.1 - 1.1e-147 492.0 0.0 1.3e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) IBB PF01749.15 KII92564.1 - 7.4 6.8 7.5 0.89 9.7 0.4 2.5 3 0 0 3 3 3 0 Importin beta binding domain Topoisom_bac PF01131.15 KII92565.1 - 3.3e-97 325.8 0.0 4e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KII92565.1 - 9e-21 73.7 0.0 3.4e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 Toprim domain zf-GRF PF06839.7 KII92565.1 - 5e-17 61.5 8.7 6.6e-10 38.7 1.6 2.9 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC_3 PF13917.1 KII92565.1 - 5e-07 29.3 3.6 0.0026 17.4 0.1 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 KII92565.1 - 5.1e-07 29.3 16.3 0.0008 19.2 2.9 2.7 2 0 0 2 2 2 2 Zinc knuckle Cytochrome_C554 PF13435.1 KII92565.1 - 0.0037 17.3 1.8 0.0098 15.9 1.2 1.7 1 0 0 1 1 1 1 Cytochrome c554 and c-prime zf-CCHC_2 PF13696.1 KII92565.1 - 0.19 11.2 5.1 5.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII92565.1 - 1 9.0 9.2 5.9 6.6 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Malate_synthase PF01274.17 KII92566.1 - 7.1e-196 651.2 0.0 8e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Dehydratase_SU PF02287.10 KII92566.1 - 0.11 12.2 0.2 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Dehydratase small subunit F-box-like PF12937.2 KII92567.1 - 0.0014 18.2 0.3 0.0036 16.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII92567.1 - 0.041 13.5 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 F-box domain LRR_7 PF13504.1 KII92570.1 - 4.3 7.9 7.6 2.5e+02 2.6 0.0 5.9 7 0 0 7 7 7 0 Leucine rich repeat Hemerythrin PF01814.18 KII92571.1 - 3e-14 53.3 0.5 4.2e-14 52.8 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PriCT_2 PF08707.6 KII92571.1 - 0.0095 15.7 0.2 0.036 13.9 0.0 1.9 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) CPSF_A PF03178.10 KII92572.1 - 2.8e-91 305.9 0.0 1.7e-90 303.3 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KII92572.1 - 4.4e-80 269.2 0.0 6.4e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term OsmC PF02566.14 KII92573.1 - 1.5e-13 50.7 0.0 3e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 OsmC-like protein OsmC PF02566.14 KII92574.1 - 5.8e-07 29.6 0.0 7.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein DUF3077 PF11275.3 KII92574.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) UPF0203 PF05254.7 KII92576.1 - 0.00051 19.8 1.2 0.0014 18.3 0.8 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KII92576.1 - 0.013 15.2 0.5 0.077 12.7 0.0 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KII92576.1 - 0.027 14.4 0.5 0.042 13.7 0.3 1.4 1 1 0 1 1 1 0 CHCH domain COX17 PF05051.8 KII92576.1 - 0.064 13.2 0.8 0.12 12.4 0.5 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF1746 PF08508.5 KII92577.1 - 2e-05 24.5 0.1 3.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) FA_hydroxylase PF04116.8 KII92577.1 - 0.16 12.3 4.1 0.21 12.0 2.6 1.4 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily Tetraspannin PF00335.15 KII92578.1 - 1e-06 28.2 9.9 1e-06 28.2 6.9 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF898 PF05987.8 KII92578.1 - 0.011 14.5 0.6 0.011 14.5 0.4 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) ABC2_membrane_2 PF12679.2 KII92578.1 - 0.44 9.3 5.4 0.59 8.9 3.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Sybindin PF04099.7 KII92580.1 - 1.3e-19 70.3 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.18 KII92581.1 - 6.8e-66 222.0 0.1 9.5e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII92581.1 - 2.2e-14 53.0 0.0 5.1e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII92581.1 - 1.7e-07 31.2 0.0 3.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.2 KII92581.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SOG2 PF10428.4 KII92581.1 - 0.0018 17.0 2.7 0.0018 17.0 1.9 1.7 2 0 0 2 2 2 1 RAM signalling pathway protein PsbU PF06514.6 KII92581.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Mito_carr PF00153.22 KII92582.1 - 3.8e-14 52.1 0.0 6e-08 32.2 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF389 PF04087.9 KII92582.1 - 0.071 13.0 0.7 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Zn_clus PF00172.13 KII92583.1 - 9.8e-07 28.5 5.3 1.8e-06 27.7 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Packaging_FI PF14000.1 KII92583.1 - 0.015 15.5 0.8 0.1 12.7 0.0 2.5 3 0 0 3 3 3 0 DNA packaging protein FI zf-CCCH PF00642.19 KII92584.1 - 6.8e-14 51.1 15.3 3.7e-07 29.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KII92584.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII92584.1 - 0.0096 15.5 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg14 PF08660.6 KII92585.1 - 1.9e-51 174.4 0.0 2.3e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.23 KII92586.1 - 1.6e-28 97.0 7.8 4.4e-05 22.9 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat APC8 PF04049.8 KII92586.1 - 4.7e-26 91.2 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 KII92586.1 - 2.9e-24 84.5 13.7 1.9e-10 40.1 2.5 6.0 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KII92586.1 - 7.1e-21 72.4 20.3 0.0013 18.4 0.0 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KII92586.1 - 9e-21 72.0 4.9 0.0012 18.5 0.0 7.8 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KII92586.1 - 1e-14 54.7 31.5 3.3e-05 24.4 0.3 7.6 6 2 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KII92586.1 - 1.2e-14 53.9 22.1 4.5e-07 29.7 0.1 6.2 4 1 5 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KII92586.1 - 3.3e-14 52.0 18.8 0.0053 17.2 0.1 9.3 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KII92586.1 - 2.4e-10 39.4 19.8 0.17 11.7 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KII92586.1 - 4.7e-08 32.6 4.4 0.065 13.4 0.3 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KII92586.1 - 6.3e-08 32.6 13.3 0.0017 18.4 1.5 5.1 3 1 2 5 5 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KII92586.1 - 1.9e-06 28.0 6.7 0.44 10.9 0.0 5.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KII92586.1 - 2.7e-06 27.1 14.1 0.0004 20.1 0.6 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII92586.1 - 4.3e-05 23.6 13.8 1.3 9.6 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.5 KII92586.1 - 7.5e-05 21.6 0.3 0.14 10.8 0.0 2.5 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 KII92586.1 - 9.6e-05 21.5 9.4 0.0012 17.9 1.9 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.15 KII92586.1 - 0.056 13.0 0.8 0.38 10.3 0.0 2.7 3 0 0 3 3 3 0 Region in Clathrin and VPS MIT PF04212.13 KII92586.1 - 0.12 12.2 3.4 0.43 10.4 0.1 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain GLTSCR1 PF15249.1 KII92587.1 - 5.1e-23 81.2 0.2 9.2e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region DUF2786 PF10979.3 KII92588.1 - 3.6e-12 45.8 4.2 3.6e-12 45.8 2.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) DUF1837 PF08878.6 KII92588.1 - 0.056 13.0 0.6 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) FliL PF03748.9 KII92588.1 - 5.7 6.9 6.9 5.1 7.1 0.2 2.7 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL LSM PF01423.17 KII92589.1 - 3.6e-12 45.6 0.3 4.7e-12 45.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KII92589.1 - 0.053 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain E3_binding PF02817.12 KII92589.1 - 0.068 12.8 0.3 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain Voltage_CLC PF00654.15 KII92590.1 - 2.2e-94 316.3 21.4 2.2e-94 316.3 14.8 2.2 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KII92590.1 - 0.0059 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 CBS domain CbtB PF09489.5 KII92590.1 - 0.14 12.0 0.6 11 5.9 0.0 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF1674 PF07896.7 KII92591.1 - 4.7e-13 49.1 1.7 7e-13 48.5 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.13 KII92592.1 - 7.5e-24 83.9 0.0 1.2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII92592.1 - 3e-09 36.6 11.4 4.9e-09 35.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pterin_4a PF01329.14 KII92594.1 - 2.4e-14 52.8 0.2 5.4e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Ctr PF04145.10 KII92595.1 - 5.1e-38 130.3 0.9 5.9e-38 130.1 0.6 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF4191 PF13829.1 KII92595.1 - 0.37 9.8 2.1 0.34 9.9 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Abi PF02517.11 KII92595.1 - 0.84 9.8 6.0 0.46 10.6 0.3 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity Proteasome PF00227.21 KII92596.1 - 2.5e-54 183.4 0.1 4.7e-54 182.5 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII92596.1 - 0.0046 16.2 5.6 0.072 12.4 3.9 2.4 1 1 0 1 1 1 1 Proteasome subunit A N-terminal signature F-box-like PF12937.2 KII92598.1 - 0.00012 21.6 0.4 0.00035 20.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like dsrm PF00035.20 KII92599.1 - 5.8e-10 39.6 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KII92599.1 - 7.1e-08 32.4 0.0 9.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KII92599.1 - 0.0043 17.4 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Spore_YtfJ PF09579.5 KII92599.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) CHZ PF09649.5 KII92601.1 - 8e-13 47.3 0.9 8e-13 47.3 0.6 3.0 3 1 0 3 3 3 1 Histone chaperone domain CHZ Prothymosin PF03247.9 KII92601.1 - 0.0091 16.1 17.9 0.0091 16.1 12.4 2.1 2 0 0 2 2 2 1 Prothymosin/parathymosin family Retinal PF15449.1 KII92601.1 - 0.91 7.1 5.7 0.92 7.0 4.0 1.2 1 0 0 1 1 1 0 Retinal protein SDA1 PF05285.7 KII92601.1 - 3.5 6.8 22.5 4.1 6.5 15.6 1.1 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.6 KII92601.1 - 3.9 6.6 20.4 5 6.3 14.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 KII92601.1 - 5.5 6.6 16.3 0.11 12.1 6.4 1.7 1 1 1 2 2 2 0 FAM176 family Acetyltransf_3 PF13302.1 KII92602.1 - 8.7e-19 68.0 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII92602.1 - 2.5e-08 33.8 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KII92602.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII92602.1 - 0.0005 19.7 0.0 0.0011 18.6 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KII92602.1 - 0.003 17.5 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SKI PF01202.17 KII92604.1 - 6.1e-11 42.4 0.0 1.5e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 KII92604.1 - 1.7e-06 28.3 0.0 5.3e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII92604.1 - 8.3e-06 25.7 0.0 1.3e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII92604.1 - 8.7e-06 26.5 0.0 1e-05 26.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII92604.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Cytidylate_kin2 PF13189.1 KII92604.1 - 0.0093 15.8 0.0 0.092 12.6 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 KII92604.1 - 0.012 15.9 0.0 0.042 14.1 0.0 1.7 1 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 KII92604.1 - 0.013 14.8 0.0 0.64 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KII92604.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KII92604.1 - 0.031 14.4 0.3 0.1 12.7 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KII92604.1 - 0.06 12.9 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 KII92604.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KII92604.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 KII92604.1 - 0.1 12.1 0.1 0.34 10.5 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Thymidylate_kin PF02223.12 KII92604.1 - 0.16 11.3 0.1 4.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Rpr2 PF04032.11 KII92605.1 - 4.6e-24 84.1 0.1 2e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF164 PF02591.10 KII92605.1 - 0.057 13.2 0.3 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain Ribosomal_S8e PF01201.17 KII92606.1 - 2.4e-38 131.2 5.6 5.7e-38 130.0 3.9 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 KII92606.1 - 0.18 11.7 1.1 0.19 11.6 0.1 1.4 2 0 0 2 2 2 0 Mer2 DUF3959 PF13105.1 KII92606.1 - 1 8.5 3.3 0.43 9.8 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) Yip1 PF04893.12 KII92607.1 - 7.2e-07 28.8 10.2 1.2e-06 28.1 7.1 1.4 1 0 0 1 1 1 1 Yip1 domain Pterin_4a PF01329.14 KII92608.1 - 4.5e-14 51.9 0.0 7.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase eIF3g PF12353.3 KII92608.1 - 0.00094 19.1 16.9 0.11 12.3 0.1 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G Cas_CXXC_CXXC PF09706.5 KII92608.1 - 0.35 11.0 3.0 30 4.8 0.0 3.2 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) MU117 PF15474.1 KII92608.1 - 0.72 10.3 6.0 14 6.2 0.1 3.3 1 1 2 3 3 3 0 Meiotically up-regulated gene family Aldo_ket_red PF00248.16 KII92609.1 - 7.8e-37 126.6 0.0 1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.18 KII92610.1 - 6e-09 35.4 24.0 0.0012 18.6 0.5 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KII92610.1 - 1.1e-05 24.8 14.8 0.0044 16.4 0.2 4.0 2 1 2 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.1 KII92610.1 - 0.0023 17.5 20.8 0.14 11.8 0.3 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.1 KII92610.1 - 0.0071 15.8 1.1 0.0071 15.8 0.7 3.8 3 0 0 3 3 3 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 KII92610.1 - 8.9 6.1 14.0 15 5.4 0.1 4.2 3 1 1 4 4 4 0 Zinc knuckle DUF4004 PF13171.1 KII92611.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) FAD_binding_3 PF01494.14 KII92612.1 - 2.5e-75 253.7 0.0 3.3e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KII92612.1 - 5.1e-07 28.9 0.3 0.0033 16.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KII92612.1 - 1.4e-06 28.3 0.0 1.1e-05 25.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII92612.1 - 2.6e-06 27.7 0.2 0.0034 17.7 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII92612.1 - 5e-06 25.6 0.1 1.3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KII92612.1 - 1.2e-05 23.9 0.9 3.9e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KII92612.1 - 2.1e-05 24.4 0.0 5.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII92612.1 - 0.00042 19.4 0.1 0.00075 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KII92612.1 - 0.00076 18.4 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KII92612.1 - 0.0018 18.4 0.1 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII92612.1 - 0.0025 16.9 0.9 0.0038 16.3 0.6 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KII92612.1 - 0.021 14.5 0.1 0.047 13.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KII92612.1 - 0.031 13.1 0.1 0.052 12.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KII92612.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Yippee-Mis18 PF03226.9 KII92613.1 - 6.8e-16 58.0 0.0 9.1e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Dioxygenase_C PF00775.16 KII92614.1 - 3.7e-09 36.0 0.0 4e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase RdRP PF05183.7 KII92616.1 - 3.3e-113 379.3 0.0 4.3e-113 379.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Amidohydro_2 PF04909.9 KII92617.1 - 1.3e-31 110.1 1.6 2.7e-31 109.1 1.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 KII92617.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Asparaginase RRM_1 PF00076.17 KII92619.1 - 1.7e-17 62.7 0.1 1.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII92619.1 - 2.9e-11 43.0 0.0 2e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII92619.1 - 4e-09 36.3 0.0 2.6e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 KII92620.1 - 2.4e-14 53.1 0.1 3.7e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII92620.1 - 1.7e-11 44.6 0.0 3.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII92620.1 - 5.2e-11 42.1 0.0 7.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KII92620.1 - 2.7e-10 40.5 0.0 6.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII92620.1 - 8.8e-10 38.6 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII92620.1 - 4.6e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII92620.1 - 4.8e-08 32.5 0.1 8.2e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KII92620.1 - 3.5e-07 29.5 0.0 5.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 KII92620.1 - 3.9e-07 29.3 0.0 5.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 KII92620.1 - 5.4e-07 28.6 0.0 7.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KII92620.1 - 1.7e-06 28.4 0.0 3.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII92620.1 - 2.6e-06 27.7 0.0 5.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KII92620.1 - 2.7e-05 23.4 0.1 6.6e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 KII92620.1 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KII92620.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KII92620.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KII92620.1 - 0.0026 17.7 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 KII92620.1 - 0.0027 18.4 0.0 0.0059 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII92620.1 - 0.0033 16.5 0.1 0.0084 15.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 KII92620.1 - 0.0055 16.2 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 KII92620.1 - 0.02 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Cons_hypoth95 PF03602.10 KII92620.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2367 PF10164.4 KII92621.1 - 8.9e-06 25.4 3.5 1.7e-05 24.5 2.4 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) LRR_4 PF12799.2 KII92622.1 - 0.00022 20.7 0.4 2 8.1 0.0 5.5 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) DAO PF01266.19 KII92622.1 - 0.018 13.9 0.0 0.49 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase LRR_8 PF13855.1 KII92624.1 - 0.00025 20.7 0.6 2.4 8.0 0.0 5.1 6 0 0 6 6 6 2 Leucine rich repeat Exo_endo_phos PF03372.18 KII92626.1 - 1.7e-20 74.0 0.1 2.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KII92626.1 - 3.2e-19 68.1 7.1 1.8e-09 37.0 0.5 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII92626.1 - 5e-14 51.7 12.7 1.8e-09 37.1 1.7 2.7 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KII92626.1 - 1.1e-09 36.9 4.6 0.035 14.1 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KII92626.1 - 8.2e-07 28.2 9.8 0.14 12.4 0.3 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KII92626.1 - 0.21 11.7 8.1 11 6.4 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat GHMP_kinases_N PF00288.21 KII92627.1 - 2e-08 34.1 4.5 4.1e-08 33.1 3.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Glyco_hydro_cc PF11790.3 KII92629.1 - 3.2e-74 249.3 3.9 3.8e-74 249.1 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SBP_bac_11 PF13531.1 KII92629.1 - 0.17 11.5 2.2 0.71 9.4 1.4 2.1 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein PIG-U PF06728.8 KII92631.1 - 1.5e-106 356.5 28.0 1.7e-106 356.3 19.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF4462 PF14692.1 KII92631.1 - 0.33 10.2 2.2 0.24 10.6 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) peroxidase PF00141.18 KII92632.1 - 2.1e-45 155.0 0.0 3.6e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase zf-LYAR PF08790.6 KII92634.1 - 5.3e-13 48.4 4.1 5.3e-13 48.4 2.8 1.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger PBP-Tp47_a PF14889.1 KII92634.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Autophagy_N PF03986.8 KII92635.1 - 1.6e-46 157.6 0.0 1.9e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_N PF03986.8 KII92636.1 - 4e-47 159.6 0.0 5.4e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Lectin_N PF03954.9 KII92637.1 - 0.071 12.5 2.0 0.11 11.9 1.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2074 PF09847.4 KII92637.1 - 0.4 9.3 23.1 0.49 9.0 16.0 1.0 1 0 0 1 1 1 0 Predicted permease (DUF2074) DUF3792 PF12670.2 KII92637.1 - 4.4 7.1 22.0 0.69 9.7 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Autophagy_N PF03986.8 KII92638.1 - 3.1e-46 156.7 0.1 6.3e-46 155.7 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KII92638.1 - 3.5e-24 84.7 0.3 6.1e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KII92638.1 - 4.1e-12 44.9 3.2 7.1e-12 44.2 2.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CUE PF02845.11 KII92639.1 - 4.5e-10 38.8 0.0 7.6e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain Tyrosinase PF00264.15 KII92640.1 - 2.7e-30 106.2 10.0 3.6e-30 105.7 6.9 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyridoxal_deC PF00282.14 KII92641.1 - 2e-16 59.4 0.0 3.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KII92641.1 - 7.1e-06 24.9 0.0 0.00096 17.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KII92641.1 - 5.7e-05 22.3 0.2 8.7e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_C PF02752.17 KII92644.1 - 3.7e-09 36.7 0.3 9.4e-08 32.2 0.1 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KII92644.1 - 1.6e-08 34.4 0.0 4.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KII92644.1 - 0.0033 16.9 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like ATP-synt_C PF00137.16 KII92645.1 - 6.6e-27 93.2 26.1 7.3e-17 61.0 6.8 2.8 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 KII92645.1 - 0.24 11.6 0.6 1.1 9.5 0.2 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.19 KII92645.1 - 1.7 8.3 8.1 2.3 7.8 2.8 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF373 PF04123.8 KII92645.1 - 3.2 6.6 9.0 5.7 5.8 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Cation_efflux PF01545.16 KII92645.1 - 7.2 5.5 12.5 0.15 11.0 1.5 2.5 1 1 1 2 2 2 0 Cation efflux family Arf PF00025.16 KII92646.1 - 2e-36 124.8 0.0 5.2e-36 123.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KII92646.1 - 5.1e-12 45.1 0.1 4.5e-07 28.9 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KII92646.1 - 2.3e-08 34.5 0.0 3.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KII92646.1 - 1.9e-07 30.6 0.0 2.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KII92646.1 - 9e-06 24.9 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KII92646.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KII92646.1 - 2e-05 23.9 0.0 3.8e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KII92646.1 - 0.0005 20.2 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KII92646.1 - 0.0005 19.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KII92646.1 - 0.0012 19.1 0.2 0.0039 17.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 KII92646.1 - 0.0026 18.1 0.4 0.0056 17.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KII92646.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KII92646.1 - 0.012 15.0 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KII92646.1 - 0.017 15.0 0.3 0.042 13.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KII92646.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 KII92646.1 - 0.017 14.4 0.1 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase KAP_NTPase PF07693.9 KII92646.1 - 0.024 13.6 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 KII92646.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KII92646.1 - 0.033 13.2 0.2 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 KII92646.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KII92646.1 - 0.035 14.9 1.0 0.072 13.9 0.7 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KII92646.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KII92646.1 - 0.12 12.6 1.3 0.28 11.5 0.9 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII92646.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KII92646.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 KII92646.1 - 0.39 10.6 2.0 0.42 10.5 0.1 2.0 3 0 0 3 3 2 0 AAA domain adh_short PF00106.20 KII92647.1 - 1.1e-23 83.9 0.1 2.3e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII92647.1 - 2.9e-11 43.6 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII92647.1 - 1.2e-06 28.3 0.3 5e-06 26.3 0.2 1.9 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KII92647.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KII92647.1 - 0.02 14.6 0.5 0.042 13.6 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KII92647.1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Voltage_CLC PF00654.15 KII92648.1 - 3.9e-88 295.8 36.6 3.9e-88 295.8 25.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KII92648.1 - 8.4e-14 51.0 0.6 9.7e-07 28.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain SpoIISA_toxin PF14171.1 KII92648.1 - 0.12 11.6 0.1 0.34 10.1 0.1 1.7 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF1228 PF06779.9 KII92648.1 - 9.6 6.3 12.4 0.2 11.6 0.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1228) Phage_pRha PF09669.5 KII92650.1 - 0.032 14.5 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) DUF663 PF04950.7 KII92651.1 - 1.8e-100 335.7 0.0 2.9e-100 335.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KII92651.1 - 1e-19 69.8 0.0 2.5e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Muskelin_N PF06588.6 KII92652.1 - 1.9e-15 57.0 0.0 2e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Muskelin N-terminus Muskelin_N PF06588.6 KII92653.1 - 1.8e-36 125.7 0.0 1.5e-35 122.7 0.0 2.0 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_3 PF13415.1 KII92653.1 - 3.8e-29 100.1 9.3 6.2e-09 35.7 0.0 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KII92653.1 - 5.4e-27 93.3 4.3 6.6e-08 32.1 0.1 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KII92653.1 - 5.8e-21 74.0 0.5 1.5e-07 31.1 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KII92653.1 - 6.5e-19 67.2 5.2 0.00015 21.8 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 KII92653.1 - 4.6e-18 64.4 4.3 6.5e-07 28.7 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Sad1_UNC PF07738.8 KII92653.1 - 0.22 11.3 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Prefoldin_2 PF01920.15 KII92654.1 - 9.8e-22 76.7 10.0 1.2e-21 76.4 6.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Laminin_II PF06009.7 KII92654.1 - 0.00057 19.6 2.1 0.041 13.6 0.2 2.1 2 0 0 2 2 2 1 Laminin Domain II DASH_Dam1 PF08653.5 KII92654.1 - 0.00068 19.3 2.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 DASH complex subunit Dam1 Seryl_tRNA_N PF02403.17 KII92654.1 - 0.00071 19.5 6.3 0.17 11.8 0.3 2.2 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 KII92654.1 - 0.0011 18.5 9.2 0.017 14.7 0.9 2.1 1 1 1 2 2 2 2 Prefoldin subunit BLOC1_2 PF10046.4 KII92654.1 - 0.0039 17.2 5.2 0.17 12.0 1.2 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 KII92654.1 - 0.0046 16.7 12.9 0.0088 15.8 1.7 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KII92654.1 - 0.0053 16.2 6.3 0.34 10.4 0.8 2.2 2 0 0 2 2 2 2 Septum formation initiator FlxA PF14282.1 KII92654.1 - 0.011 15.7 7.8 0.2 11.6 0.8 2.2 2 0 0 2 2 2 0 FlxA-like protein TBPIP PF07106.8 KII92654.1 - 0.014 14.9 9.9 0.038 13.5 0.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF948 PF06103.6 KII92654.1 - 0.02 14.7 0.9 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 KII92654.1 - 0.022 14.6 4.1 2 8.3 1.0 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec8_exocyst PF04048.9 KII92654.1 - 0.036 13.7 1.9 1.5 8.4 0.0 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.5 KII92654.1 - 0.039 14.0 4.3 0.059 13.4 3.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FliD_C PF07195.7 KII92654.1 - 0.042 13.1 3.0 0.13 11.5 0.1 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus NYD-SP28 PF14772.1 KII92654.1 - 0.047 13.7 9.5 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Sperm tail TPR_MLP1_2 PF07926.7 KII92654.1 - 0.064 13.0 10.5 0.09 12.5 6.9 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF919 PF06034.6 KII92654.1 - 0.072 12.7 3.6 0.94 9.1 0.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Spc7 PF08317.6 KII92654.1 - 0.079 11.6 12.1 0.12 10.9 8.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.1 KII92654.1 - 0.088 13.2 9.1 0.89 10.0 1.3 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KII92654.1 - 0.095 12.2 12.3 0.14 11.7 8.5 1.3 1 0 0 1 1 1 0 IncA protein TPR_11 PF13414.1 KII92654.1 - 0.15 11.7 0.8 0.25 11.0 0.1 1.8 2 0 0 2 2 1 0 TPR repeat DUF2951 PF11166.3 KII92654.1 - 0.16 11.8 4.8 0.69 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF1049 PF06305.6 KII92654.1 - 0.18 11.2 2.0 3 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2540 PF10802.3 KII92654.1 - 0.19 11.4 1.8 1.1 9.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2540) AAA_23 PF13476.1 KII92654.1 - 0.19 12.0 7.6 0.26 11.5 5.3 1.2 1 0 0 1 1 1 0 AAA domain DUF4047 PF13256.1 KII92654.1 - 0.2 11.5 2.6 0.19 11.6 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Snapin_Pallidin PF14712.1 KII92654.1 - 0.21 11.8 5.8 2.7 8.3 0.2 2.6 2 1 1 3 3 3 0 Snapin/Pallidin Streptin-Immun PF11083.3 KII92654.1 - 0.46 10.5 4.9 0.86 9.6 3.2 1.6 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF972 PF06156.8 KII92654.1 - 0.46 10.8 7.9 6 7.2 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4208 PF13907.1 KII92654.1 - 0.49 10.6 9.0 0.32 11.2 0.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) Rho_Binding PF08912.6 KII92654.1 - 0.51 10.6 8.3 0.44 10.8 1.8 2.3 2 0 0 2 2 2 0 Rho Binding Shugoshin_N PF07558.6 KII92654.1 - 0.58 9.9 5.0 1.1 9.0 1.1 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GAS PF13851.1 KII92654.1 - 0.63 9.1 12.7 1.5 7.9 8.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Dad2 PF08654.5 KII92654.1 - 0.73 9.8 4.9 9.7 6.2 0.3 2.4 1 1 2 3 3 3 0 DASH complex subunit Dad2 V_ATPase_I PF01496.14 KII92654.1 - 0.79 7.4 5.7 0.94 7.2 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 KII92654.1 - 0.89 9.3 7.6 6.7 6.4 0.2 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.6 KII92654.1 - 1.1 8.9 12.2 3.5e+02 0.9 8.3 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FliD_N PF02465.13 KII92654.1 - 1.3 9.4 4.0 1.6 9.1 0.4 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DASH_Dad3 PF08656.5 KII92654.1 - 1.5 8.5 7.8 0.88 9.3 0.6 2.5 3 0 0 3 3 2 0 DASH complex subunit Dad3 ADIP PF11559.3 KII92654.1 - 1.6 8.6 9.0 6 6.7 0.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Remorin_C PF03763.8 KII92654.1 - 1.6 8.2 5.9 0.59 9.6 0.7 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region DUF2730 PF10805.3 KII92654.1 - 1.9 8.2 6.0 5.8 6.7 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF2312 PF10073.4 KII92654.1 - 2 7.8 6.1 3.8 6.9 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF342 PF03961.8 KII92654.1 - 2.1 6.6 7.1 4.2 5.6 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF16 PF01519.11 KII92654.1 - 2.2 8.5 6.9 71 3.6 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 FTA4 PF13093.1 KII92654.1 - 3 7.2 8.4 4 6.8 5.6 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 H-kinase_dim PF02895.9 KII92654.1 - 3.1 8.1 5.1 20 5.6 1.0 2.2 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Syntaxin-6_N PF09177.6 KII92654.1 - 3.5 8.0 7.7 7.2 7.0 1.5 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Snf7 PF03357.16 KII92654.1 - 3.7 6.9 12.5 0.36 10.2 0.6 2.4 2 1 0 2 2 2 0 Snf7 EMP24_GP25L PF01105.19 KII92654.1 - 3.9 7.1 7.0 4.1 7.0 1.3 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD PhoU PF01895.14 KII92654.1 - 4.3 7.8 6.9 12 6.3 0.2 2.4 1 1 0 2 2 2 0 PhoU domain DUF607 PF04678.8 KII92654.1 - 6 6.7 6.6 2.9 7.8 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 NTR2 PF15458.1 KII92654.1 - 7.9 5.6 14.5 1.3e+03 -1.7 10.0 2.5 1 1 0 1 1 1 0 Nineteen complex-related protein 2 Phage_GPO PF05929.6 KII92654.1 - 8.5 5.5 7.8 22 4.1 5.3 1.6 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SET PF00856.23 KII92655.1 - 8.6e-12 45.6 0.0 4.3e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KII92655.1 - 3e-08 33.6 0.0 5.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DNA_pol_phi PF04931.8 KII92655.1 - 1.5 6.5 4.9 2.1 6.0 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_3 PF01494.14 KII92656.1 - 9.7e-21 74.1 0.1 2e-20 73.1 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KII92656.1 - 4.4e-07 29.1 1.1 0.00079 18.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 KII92656.1 - 1.2e-06 27.7 8.5 0.00065 18.7 3.6 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KII92656.1 - 1.3e-06 27.3 2.7 0.0019 16.8 0.9 2.2 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KII92656.1 - 1.3e-06 28.3 2.0 2.9e-06 27.2 1.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII92656.1 - 4.2e-05 22.7 0.6 7.9e-05 21.8 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KII92656.1 - 0.00089 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII92656.1 - 0.0023 16.8 5.0 0.0023 16.8 3.5 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KII92656.1 - 0.0026 17.5 1.2 0.0097 15.6 0.8 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KII92656.1 - 0.0027 17.6 2.6 0.0077 16.1 1.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII92656.1 - 0.0028 16.1 0.6 0.0068 14.9 0.4 1.6 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KII92656.1 - 0.0068 16.7 0.5 0.06 13.7 0.1 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KII92656.1 - 0.013 14.6 0.9 0.021 13.8 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KII92656.1 - 0.016 14.2 1.4 0.016 14.2 1.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KII92656.1 - 0.16 10.8 3.7 4.3 6.1 3.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Gti1_Pac2 PF09729.4 KII92657.1 - 1.6e-21 76.9 0.1 1e-17 64.5 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.4 KII92659.1 - 1.8e-29 102.8 0.2 2.8e-24 85.8 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family zf-MYND PF01753.13 KII92660.1 - 2.1e-05 24.2 10.2 2.1e-05 24.2 7.1 1.9 2 1 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KII92660.1 - 0.37 10.4 2.9 0.93 9.1 2.0 1.7 1 1 0 1 1 1 0 HIT zinc finger tRNA-synt_1e PF01406.14 KII92661.1 - 7.8e-126 419.2 0.1 1.2e-125 418.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KII92661.1 - 1.1e-09 37.5 2.3 5e-06 25.4 0.1 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KII92661.1 - 5.5e-07 27.9 0.1 8.7e-05 20.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 KII92661.1 - 0.0034 17.5 1.3 0.0068 16.6 0.0 2.2 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.13 KII92661.1 - 0.1 11.2 1.4 1.8 7.1 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (K) HMG_box PF00505.14 KII92663.1 - 7.8e-12 45.2 4.0 7.8e-12 45.2 2.8 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII92663.1 - 1.5e-09 38.0 4.8 1.5e-09 38.0 3.3 2.3 1 1 1 2 2 2 1 HMG-box domain MIP-T3 PF10243.4 KII92663.1 - 0.38 9.1 17.0 0.5 8.7 11.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2924 PF11149.3 KII92663.1 - 2.6 8.0 7.5 4.1 7.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Antifungal_pept PF11410.3 KII92664.1 - 0.061 13.4 2.4 0.19 11.8 1.7 1.9 1 0 0 1 1 1 0 Antifungal peptide LRR_8 PF13855.1 KII92666.1 - 0.00095 18.8 0.3 0.0081 15.8 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat F-box-like PF12937.2 KII92666.1 - 0.005 16.5 1.3 0.018 14.7 0.9 2.0 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KII92666.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 KII92667.1 - 0.076 12.7 1.5 1.7 8.4 1.0 2.5 1 1 0 1 1 1 0 F-box-like GLTP PF08718.6 KII92668.1 - 5e-38 130.4 0.0 6.1e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) TFIIA PF03153.8 KII92669.1 - 1.6e-48 166.5 6.4 1.7e-30 107.2 3.4 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit APG6 PF04111.7 KII92670.1 - 0.11 11.5 1.6 0.12 11.3 1.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Smac_DIABLO PF09057.5 KII92670.1 - 0.17 10.9 6.3 0.27 10.2 4.4 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases DUF2681 PF10883.3 KII92670.1 - 0.32 11.2 4.2 0.54 10.5 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) GrpE PF01025.14 KII92670.1 - 1.3 8.5 8.2 1.8 8.0 5.7 1.2 1 0 0 1 1 1 0 GrpE Herpes_UL25 PF01499.11 KII92670.1 - 1.6 6.9 5.2 2 6.6 3.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Birna_VP3 PF01767.11 KII92670.1 - 3.1 7.3 7.3 4.2 6.9 5.1 1.1 1 0 0 1 1 1 0 Birnavirus VP3 protein ATP-synt_B PF00430.13 KII92670.1 - 3.2 7.5 13.7 4.5 7.0 9.5 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3844 PF12955.2 KII92671.1 - 5.6e-31 106.6 4.8 8.7e-31 106.0 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) HCR PF07111.7 KII92671.1 - 0.15 10.0 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) THF_DHG_CYH PF00763.18 KII92671.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain HAD_2 PF13419.1 KII92672.1 - 8.3e-11 42.4 0.2 2.2e-07 31.2 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DEAD PF00270.24 KII92674.1 - 1.7e-11 43.9 0.0 2.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 KII92674.1 - 0.12 12.1 0.1 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KII92675.1 - 0.0046 15.7 1.9 0.0046 15.7 1.3 1.5 1 1 0 1 1 1 1 ArgK protein ERM PF00769.14 KII92675.1 - 0.019 14.4 26.8 0.026 14.0 18.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Borrelia_P83 PF05262.6 KII92675.1 - 0.1 10.8 21.3 0.12 10.6 14.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 KII92675.1 - 0.18 10.2 31.0 0.21 10.0 21.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0560 PF10577.4 KII92675.1 - 0.27 9.4 6.9 0.29 9.3 4.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AAA_13 PF13166.1 KII92675.1 - 0.39 9.1 13.1 0.47 8.8 9.1 1.0 1 0 0 1 1 1 0 AAA domain CDC27 PF09507.5 KII92675.1 - 0.82 8.8 26.1 0.95 8.6 18.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.6 KII92675.1 - 0.87 9.3 20.5 1 9.1 14.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4407 PF14362.1 KII92675.1 - 0.95 8.3 18.8 1.2 8.0 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 KII92675.1 - 1.1 7.0 5.4 1.3 6.7 3.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPX PF03105.14 KII92675.1 - 1.9 8.1 11.0 2.4 7.8 7.6 1.1 1 0 0 1 1 1 0 SPX domain GAGA_bind PF06217.7 KII92675.1 - 2 8.2 11.0 2.6 7.9 7.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Dsh_C PF12316.3 KII92675.1 - 2.9 7.9 7.6 4.1 7.4 5.3 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SAPS PF04499.10 KII92675.1 - 3.2 6.2 8.0 3.4 6.1 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4551 PF15087.1 KII92675.1 - 4.5 5.5 8.6 5.1 5.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PLRV_ORF5 PF01690.12 KII92675.1 - 4.7 6.2 13.8 5.3 6.0 9.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TATR PF03430.8 KII92675.1 - 7.7 5.0 10.3 8.2 4.9 7.1 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Hid1 PF12722.2 KII92675.1 - 8.4 3.9 9.0 8.5 3.9 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HAD_2 PF13419.1 KII92677.1 - 8.6e-05 22.8 0.0 9.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.15 KII92678.1 - 1.5e-10 40.7 0.0 2.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KII92678.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Metallophos PF00149.23 KII92679.1 - 2.1e-39 135.0 0.7 2.7e-39 134.6 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII92679.1 - 0.0044 16.8 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-C2H2_4 PF13894.1 KII92680.1 - 2.7e-08 33.5 13.8 0.00053 20.1 5.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII92680.1 - 6.9e-07 29.2 18.2 0.0019 18.4 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Tmemb_55A PF09788.4 KII92680.1 - 0.00012 21.2 2.0 0.00012 21.2 1.4 1.8 2 1 1 3 3 3 1 Transmembrane protein 55A zf-BED PF02892.10 KII92680.1 - 0.0002 21.0 6.5 0.038 13.7 0.9 2.3 1 1 1 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.1 KII92680.1 - 0.025 14.8 5.0 0.025 14.8 3.4 3.5 4 0 0 4 4 4 0 Zinc-finger double domain Terminase_GpA PF05876.7 KII92680.1 - 0.029 12.7 0.4 0.041 12.2 0.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-C2H2_6 PF13912.1 KII92680.1 - 0.037 13.9 6.7 0.85 9.6 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0547 PF10571.4 KII92680.1 - 0.095 12.4 5.3 2.6 7.8 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 KII92680.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.8 2 1 1 3 3 3 0 Nudix N-terminal DZR PF12773.2 KII92680.1 - 0.18 11.6 1.7 0.42 10.4 1.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 KII92680.1 - 0.35 10.8 5.8 4.2 7.4 0.8 2.5 2 0 0 2 2 2 0 zinc-finger OrfB_Zn_ribbon PF07282.6 KII92680.1 - 0.67 9.6 2.5 3.8 7.2 0.1 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 KII92680.1 - 1 9.3 5.4 35 4.4 3.7 2.4 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KII92680.1 - 4.2 7.6 14.0 0.81 9.9 1.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 KII92680.1 - 9.9 4.5 5.6 28 3.0 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-CCCH PF00642.19 KII92681.1 - 4.1e-09 35.9 2.5 9.3e-09 34.7 1.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KII92681.1 - 1.2e-08 34.4 5.2 1.9e-08 33.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII92681.1 - 3.4e-07 30.1 10.4 6e-07 29.3 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII92681.1 - 1.3e-06 27.9 8.7 2.3e-06 27.2 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII92681.1 - 0.00012 21.6 9.5 0.00022 20.8 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII92681.1 - 0.00013 21.6 8.1 0.00022 20.9 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII92681.1 - 0.00079 19.2 6.8 0.0018 18.0 4.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII92681.1 - 0.0028 17.3 5.6 0.0086 15.7 3.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KII92681.1 - 0.017 14.2 0.3 0.017 14.2 0.2 2.4 2 1 0 2 2 2 0 Rtf2 RING-finger zf-RanBP PF00641.13 KII92681.1 - 2.6 7.2 7.3 0.066 12.3 0.6 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-rbx1 PF12678.2 KII92681.1 - 3.2 7.9 6.9 11 6.1 4.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Lipase_GDSL PF00657.17 KII92682.1 - 1.9e-15 57.3 0.1 2.6e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KII92682.1 - 4.8e-05 23.5 3.3 9.2e-05 22.6 2.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII92683.1 - 4.5e-16 59.3 0.2 5.9e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KII92683.1 - 1.1e-05 25.6 3.7 1.6e-05 25.1 2.6 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family bZIP_2 PF07716.10 KII92684.1 - 3e-10 39.7 9.5 5.2e-10 38.9 6.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KII92684.1 - 6.5e-07 29.2 4.6 1.3e-06 28.1 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 KII92684.1 - 0.036 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA HMG_box PF00505.14 KII92685.1 - 9.4e-13 48.2 0.1 1.6e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII92685.1 - 0.00046 20.5 0.0 0.00075 19.8 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain LysM PF01476.15 KII92686.1 - 0.00081 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain SAM_2 PF07647.12 KII92688.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NUDIX PF00293.23 KII92689.1 - 7.8e-15 54.7 0.0 1.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KII92689.1 - 1.5e-13 50.9 0.9 4e-13 49.5 0.6 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KII92689.1 - 0.0024 17.3 1.0 0.0051 16.3 0.7 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HMG_box PF00505.14 KII92689.1 - 0.014 15.6 4.1 0.029 14.6 2.9 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box zf-ribbon_3 PF13248.1 KII92689.1 - 0.081 12.1 0.6 0.16 11.1 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KII92689.1 - 0.19 11.2 0.9 0.39 10.2 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.21 KII92690.1 - 1.5e-12 47.0 16.9 0.00019 21.5 1.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII92690.1 - 1.7e-08 34.2 14.9 0.0077 16.4 1.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII92690.1 - 0.00014 21.9 11.2 0.018 15.3 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KII92690.1 - 0.015 15.4 5.7 0.45 10.7 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KII92690.1 - 0.016 15.3 4.3 5.1 7.3 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 KII92690.1 - 0.12 12.4 2.2 0.37 10.8 1.5 1.9 1 1 1 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.10 KII92690.1 - 0.44 10.3 5.6 0.58 9.9 1.9 2.4 1 1 1 2 2 2 0 BED zinc finger SprT-like PF10263.4 KII92690.1 - 0.92 9.1 9.6 15 5.2 4.8 2.8 2 1 0 2 2 2 0 SprT-like family Mito_carr PF00153.22 KII92691.1 - 1.1e-64 214.1 8.0 7.4e-22 76.8 0.5 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 KII92692.1 - 3.6e-13 49.2 0.0 2.6e-11 43.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII92692.1 - 3.2e-05 23.1 0.0 8.9e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KII92693.1 - 2.6e-14 52.9 0.0 5.3e-13 48.7 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92693.1 - 3.8e-05 22.8 0.0 0.00013 21.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KII92695.1 - 7.1e-13 48.2 0.0 7.9e-11 41.5 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII92695.1 - 2.3e-05 23.6 0.0 0.0001 21.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KII92695.1 - 0.17 10.8 0.2 0.39 9.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRPRB PF09439.5 KII92696.1 - 0.031 13.4 0.2 0.056 12.6 0.1 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Pkinase PF00069.20 KII92697.1 - 3.5e-12 46.0 0.0 1.4e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII92697.1 - 0.00017 20.7 0.0 0.00062 18.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Snurportin1 PF11538.3 KII92698.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Snurportin1 Pkinase PF00069.20 KII92699.1 - 5.9e-13 48.5 0.0 1.2e-11 44.2 0.0 2.1 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92699.1 - 3.3e-05 23.0 0.0 8e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CoA_binding_2 PF13380.1 KII92700.1 - 9.5e-30 103.1 0.0 1.1e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 KII92700.1 - 0.018 15.5 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain PALP PF00291.20 KII92701.1 - 9.2e-45 153.1 0.0 4.6e-44 150.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SWIRM PF04433.12 KII92702.1 - 5.1e-16 58.5 0.0 1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KII92702.1 - 5e-09 36.0 0.0 1.4e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII92702.1 - 0.00094 19.2 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KII92702.1 - 0.51 9.9 7.6 1.1 8.8 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type TPR_11 PF13414.1 KII92703.1 - 7.5e-27 92.7 30.5 8.5e-06 25.3 0.0 10.4 8 2 1 10 10 10 7 TPR repeat TPR_1 PF00515.23 KII92703.1 - 8.5e-21 72.6 19.7 3.4e-05 23.2 0.0 10.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 KII92703.1 - 3.4e-20 70.2 35.9 0.00062 19.4 0.0 13.7 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 KII92703.1 - 4.6e-20 71.7 26.6 1.7e-05 25.0 0.0 10.5 8 2 2 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KII92703.1 - 2.7e-18 65.6 41.1 5.3e-09 35.8 0.6 10.0 8 3 2 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 KII92703.1 - 8.1e-13 47.1 16.3 0.036 13.8 0.0 11.0 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII92703.1 - 1.7e-10 40.5 44.0 0.0074 16.8 0.1 14.0 10 4 6 16 16 15 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII92703.1 - 1.9e-10 40.4 24.3 0.029 14.8 0.3 9.9 11 0 0 11 11 9 3 Tetratricopeptide repeat Apc3 PF12895.2 KII92703.1 - 2.9e-10 40.1 14.5 0.24 11.5 0.1 6.6 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KII92703.1 - 2.1e-09 37.8 52.8 0.011 16.3 1.0 11.4 10 3 4 14 14 12 6 Tetratricopeptide repeat TPR_17 PF13431.1 KII92703.1 - 4.1e-07 29.6 17.2 1.4 9.3 0.0 9.5 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII92703.1 - 5.1e-06 25.8 22.5 0.2 11.5 0.1 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 KII92703.1 - 0.0038 17.5 0.2 1.2 9.8 0.0 5.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KII92703.1 - 0.0067 16.3 36.2 0.1 12.5 0.4 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat DUF2989 PF11207.3 KII92703.1 - 0.013 14.9 4.3 1.1 8.7 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2989) ADH_zinc_N PF00107.21 KII92704.1 - 1.7e-18 66.3 0.0 2.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII92704.1 - 4.8e-08 33.9 0.0 8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII92704.1 - 0.00074 19.4 0.1 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain DUF2855 PF11017.3 KII92704.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) zf-HIT PF04438.11 KII92705.1 - 1.5e-08 34.1 14.0 2.2e-08 33.5 9.7 1.3 1 0 0 1 1 1 1 HIT zinc finger TGF_beta_GS PF08515.7 KII92705.1 - 0.097 12.0 1.9 0.19 11.0 1.3 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif TPR_16 PF13432.1 KII92705.1 - 0.17 12.5 2.0 0.45 11.2 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-B_box PF00643.19 KII92705.1 - 1.1 9.2 9.0 1.6 8.6 6.3 1.3 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.1 KII92705.1 - 3.9 7.9 11.7 6.2 7.3 8.1 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RNase_T PF00929.19 KII92706.1 - 7.2e-16 58.9 0.0 1.1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease ADH_zinc_N PF00107.21 KII92707.1 - 1.3e-18 66.7 0.0 2.7e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII92707.1 - 2.8e-07 31.4 0.0 4.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII92707.1 - 0.00047 20.1 0.1 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Cytochrom_B561 PF03188.11 KII92708.1 - 4.4e-10 39.5 2.1 8.4e-10 38.6 1.4 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KII92708.1 - 2.1e-08 34.1 0.3 4.9e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 DOMON domain DUF4181 PF13789.1 KII92708.1 - 0.06 13.2 0.3 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF2427 PF10348.4 KII92708.1 - 0.063 12.8 4.6 0.04 13.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MARVEL PF01284.18 KII92708.1 - 0.26 11.1 7.0 1.6 8.5 0.1 3.4 3 1 1 4 4 4 0 Membrane-associating domain API5 PF05918.6 KII92709.1 - 1.9e-12 46.4 0.2 2.4e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 KII92709.1 - 9.1e-05 22.6 0.4 0.033 14.4 0.1 2.8 2 1 0 2 2 2 2 HEAT repeats FUSC_2 PF13515.1 KII92710.1 - 9.3e-19 67.6 10.7 9.3e-19 67.6 7.4 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KII92710.1 - 9.2e-15 54.1 6.5 6.8e-13 47.9 3.2 3.0 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 KII92710.1 - 3.6e-13 48.9 3.2 2e-10 39.9 0.3 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 KII92710.1 - 3.2e-08 33.4 1.7 1.2e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) FUSC-like PF12805.2 KII92710.1 - 0.00068 18.6 4.1 0.085 11.7 0.1 2.4 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS Asp PF00026.18 KII92711.1 - 6.6e-64 216.1 4.4 8.4e-64 215.8 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII92711.1 - 2.4e-08 34.0 2.6 2.4e-08 34.0 1.8 2.4 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII92711.1 - 0.041 14.3 0.6 0.041 14.3 0.4 3.5 3 1 0 3 3 3 0 Aspartyl protease DUF1517 PF07466.6 KII92711.1 - 2.7 6.8 9.4 7.7 5.4 6.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Fungal_trans PF04082.13 KII92712.1 - 1.9e-14 53.1 0.4 7.6e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII92712.1 - 1.4e-07 31.2 13.5 2.7e-07 30.3 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain stn_TNFRSF12A PF12191.3 KII92713.1 - 0.04 13.9 0.1 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TilS_C PF11734.3 KII92713.1 - 0.049 12.8 0.1 0.055 12.7 0.0 1.3 1 1 0 1 1 1 0 TilS substrate C-terminal domain Pkinase PF00069.20 KII92714.1 - 1.3e-70 237.4 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92714.1 - 2.2e-37 128.5 0.0 3.3e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KII92714.1 - 1.5e-16 60.2 0.2 3.1e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KII92714.1 - 7.3e-07 28.4 0.0 4.9e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KII92714.1 - 3.7e-05 22.9 0.3 0.00018 20.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII92714.1 - 0.0017 18.1 0.0 0.0044 16.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Zn_clus PF00172.13 KII92715.1 - 6.2e-05 22.8 7.6 0.00013 21.8 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPC22 PF04573.7 KII92716.1 - 1.8e-40 138.0 0.0 2e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit S-methyl_trans PF02574.11 KII92717.1 - 3.9e-36 124.9 0.0 2.1e-17 63.3 0.0 2.1 1 1 1 2 2 2 2 Homocysteine S-methyltransferase Ribosomal_S2 PF00318.15 KII92718.1 - 1e-44 152.2 0.1 1.5e-23 83.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Lipase_3 PF01764.20 KII92719.1 - 3.8e-34 117.3 0.0 1.2e-33 115.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KII92719.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KII92719.1 - 0.079 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 KII92720.1 - 2.1e-29 101.9 0.0 2.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PELOTA_1 PF15608.1 KII92720.1 - 0.022 14.5 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 PELOTA RNA binding domain Acyltransferase PF01553.16 KII92721.1 - 6.5e-17 61.2 0.0 1.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase CobD_Cbib PF03186.8 KII92721.1 - 0.013 14.5 1.2 0.021 13.8 0.8 1.2 1 0 0 1 1 1 0 CobD/Cbib protein CHAD PF05235.9 KII92721.1 - 0.024 14.2 1.1 0.052 13.1 0.8 1.5 1 0 0 1 1 1 0 CHAD domain E1-E2_ATPase PF00122.15 KII92722.1 - 1.1e-62 211.0 1.0 1.1e-62 211.0 0.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KII92722.1 - 4.8e-25 89.2 0.0 1.2e-24 87.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII92722.1 - 1.2e-13 51.7 0.0 2.4e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KII92722.1 - 2.2e-10 39.8 0.0 5.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KII92722.1 - 0.00013 21.6 0.1 0.0021 17.6 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII92722.1 - 0.098 12.6 0.2 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit LRR_4 PF12799.2 KII92724.1 - 2e-53 177.2 51.6 1.3e-07 31.0 2.3 12.4 7 3 6 13 13 13 13 Leucine Rich repeats (2 copies) PP2C PF00481.16 KII92724.1 - 1.3e-43 149.2 0.0 2.1e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 KII92724.1 - 2e-41 139.5 53.0 2.6e-11 43.0 5.8 10.6 5 3 6 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 KII92724.1 - 7.7e-27 93.8 0.0 1.7e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KII92724.1 - 6.3e-24 80.3 58.5 0.026 14.5 0.1 19.8 21 1 0 21 21 21 8 Leucine Rich Repeat LRR_7 PF13504.1 KII92724.1 - 2.1e-11 42.0 51.7 1.5 9.3 0.1 17.3 19 0 0 19 19 19 5 Leucine rich repeat LRR_6 PF13516.1 KII92724.1 - 2.1e-07 30.3 46.5 4.2 7.7 0.2 15.7 15 3 3 18 18 18 4 Leucine Rich repeat RA PF00788.18 KII92724.1 - 2.7e-05 24.5 0.0 5.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Mg_trans_NIPA PF05653.9 KII92725.1 - 1.2e-83 280.6 28.1 1.5e-83 280.2 19.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KII92725.1 - 1.6e-06 28.2 9.6 1.6e-06 28.2 6.7 3.5 2 2 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KII92725.1 - 8.5e-06 25.8 13.6 8.5e-06 25.8 9.4 3.7 2 2 0 3 3 3 1 EamA-like transporter family GST_C_3 PF14497.1 KII92726.1 - 4.8e-09 36.6 0.0 7.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KII92726.1 - 4.7e-07 29.6 0.1 9.3e-07 28.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII92726.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KII92726.1 - 0.031 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Rad9 PF04139.8 KII92728.1 - 1.1e-47 162.3 0.0 1.3e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 ATP-sulfurylase PF01747.12 KII92729.1 - 1.1e-85 286.3 0.5 1.6e-85 285.8 0.4 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KII92729.1 - 5.9e-54 181.9 0.0 8.5e-54 181.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KII92729.1 - 1.8e-53 180.2 0.0 3e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KII92729.1 - 0.025 14.4 0.5 0.047 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KII92729.1 - 0.028 13.6 0.0 0.057 12.6 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 KII92729.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ERO1 PF04137.10 KII92731.1 - 1.7e-115 385.8 0.0 2.1e-115 385.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Flu_M2 PF00599.12 KII92732.1 - 0.047 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) ILVD_EDD PF00920.16 KII92733.1 - 6.5e-196 651.7 0.0 7.5e-196 651.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.23 KII92734.1 - 6.1e-16 57.2 0.5 0.00074 19.0 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KII92734.1 - 3.3e-15 55.4 3.1 8.2e-10 38.1 0.5 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KII92734.1 - 1.3e-13 49.7 3.8 0.0038 17.0 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII92734.1 - 2.1e-11 44.1 3.5 8.3e-09 35.8 0.1 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII92734.1 - 4.8e-09 36.0 4.2 0.0037 17.7 0.0 5.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII92734.1 - 5.8e-09 35.7 7.4 0.001 18.9 0.2 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII92734.1 - 1.4e-07 31.1 0.2 0.34 11.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII92734.1 - 1.2e-05 24.6 0.4 0.4 10.5 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII92734.1 - 1.5e-05 24.4 5.0 4.1 7.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII92734.1 - 0.00012 22.3 4.8 0.86 9.9 0.2 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII92734.1 - 0.00041 20.6 0.5 1.9 9.1 0.0 4.7 3 1 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.9 KII92734.1 - 0.0016 17.6 0.0 0.041 13.0 0.0 2.8 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_10 PF13374.1 KII92734.1 - 0.0024 17.7 5.2 9.7 6.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KII92734.1 - 0.0044 17.1 0.1 0.013 15.5 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 HlyIII PF03006.15 KII92735.1 - 3.2e-32 111.7 21.7 5.5e-32 110.9 15.0 1.4 1 0 0 1 1 1 1 Haemolysin-III related DUF1129 PF06570.6 KII92735.1 - 0.021 14.1 0.7 0.043 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 7TMR-DISM_7TM PF07695.6 KII92735.1 - 0.067 12.8 16.0 0.8 9.3 0.2 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling ABC2_membrane_5 PF13346.1 KII92735.1 - 4.6 6.4 15.0 0.038 13.2 4.2 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Pept_tRNA_hydro PF01195.14 KII92736.1 - 9.6e-35 119.7 0.0 1.1e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_hydro_92 PF07971.7 KII92737.1 - 3.9e-123 411.7 1.2 4.9e-123 411.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 IF-2B PF01008.12 KII92738.1 - 1.2e-60 204.9 0.0 1.4e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pox_A51 PF04948.8 KII92739.1 - 0.017 13.8 0.6 0.018 13.6 0.4 1.0 1 0 0 1 1 1 0 Poxvirus A51 protein Zn_clus PF00172.13 KII92740.1 - 0.00019 21.2 10.8 0.00031 20.5 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KII92740.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PRA1 PF03208.14 KII92742.1 - 4.5e-41 139.7 0.4 5.2e-41 139.5 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein TPR_11 PF13414.1 KII92743.1 - 5.3e-23 80.4 15.1 1.8e-11 43.5 1.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KII92743.1 - 6.4e-21 73.0 5.6 0.00018 20.9 0.2 5.1 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KII92743.1 - 4.7e-18 63.8 7.8 0.006 16.6 0.3 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KII92743.1 - 2e-17 61.6 11.4 0.00084 19.0 0.0 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KII92743.1 - 3.2e-14 52.1 15.5 0.0012 19.2 0.2 6.1 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KII92743.1 - 6.7e-14 51.9 9.2 3.3e-07 30.5 0.4 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 KII92743.1 - 1.8e-13 50.2 8.1 1.2e-07 31.5 0.9 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KII92743.1 - 3e-11 43.6 11.2 1.2e-07 32.2 1.2 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KII92743.1 - 1.3e-09 37.1 2.5 0.052 13.3 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 KII92743.1 - 9.4e-09 35.2 5.6 0.05 13.7 0.2 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KII92743.1 - 5.3e-07 29.6 3.4 0.00033 20.7 1.0 3.3 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KII92743.1 - 4.4e-06 26.4 6.8 0.013 15.2 0.4 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KII92743.1 - 2.4e-05 23.7 7.5 0.21 11.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KII92743.1 - 0.00087 19.6 3.0 14 6.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KII92743.1 - 0.068 13.0 4.5 3.5 7.5 0.1 4.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 KII92743.1 - 0.077 11.7 0.1 0.19 10.4 0.0 1.6 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 KII92743.1 - 0.17 11.2 0.2 5.7 6.2 0.0 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 KII92743.1 - 0.23 11.4 14.9 3.4 7.7 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF533 PF04391.7 KII92743.1 - 6.2 6.1 8.0 0.46 9.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF533) zf-C2H2 PF00096.21 KII92744.1 - 1.5e-11 43.8 18.0 0.00054 20.1 0.3 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII92744.1 - 1.8e-08 34.1 18.9 0.0025 18.0 0.2 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII92744.1 - 2e-05 24.6 12.7 4.8e-05 23.4 0.0 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KII92744.1 - 0.026 14.4 5.7 1.6 8.7 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TRAF PF02176.13 KII92744.1 - 2.6 8.4 8.1 0.18 12.2 1.3 2.2 3 0 0 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 KII92744.1 - 5.1 7.4 11.2 7.7 6.8 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Abhydrolase_3 PF07859.8 KII92745.1 - 3e-29 102.1 0.0 5.3e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KII92745.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Herpes_BLLF1 PF05109.8 KII92745.1 - 1.9 6.3 9.7 3 5.7 6.7 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ADH_zinc_N PF00107.21 KII92746.1 - 4e-10 39.3 0.3 4.8e-09 35.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII92746.1 - 1.8e-07 30.9 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII92746.1 - 0.00068 20.5 0.5 0.0017 19.2 0.1 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase zf-MYND PF01753.13 KII92747.1 - 8.4e-11 41.5 17.1 1.7e-10 40.5 11.8 1.6 1 0 0 1 1 1 1 MYND finger DUF1885 PF08968.5 KII92747.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) DUF1394 PF07159.7 KII92747.1 - 0.067 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) RabGAP-TBC PF00566.13 KII92748.1 - 2.8e-50 170.7 0.1 4e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.1 KII92748.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Ran_BP1 PF00638.13 KII92749.1 - 5.1e-12 45.8 0.0 9.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 KII92749.1 - 1.1e-07 32.1 0.2 1.1e-07 32.1 0.2 7.5 3 1 1 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ank PF00023.25 KII92750.1 - 6.1e-15 54.1 0.4 5.7e-07 29.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KII92750.1 - 4.1e-13 49.1 0.9 4.6e-10 39.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KII92750.1 - 7.7e-13 48.5 0.1 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 KII92750.1 - 2.8e-09 36.8 0.0 6.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 KII92750.1 - 2.9e-08 33.1 0.3 0.0014 18.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KII92750.1 - 6.6e-08 32.8 0.3 2.3e-07 31.1 0.2 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PARP PF00644.15 KII92751.1 - 9.6e-15 54.5 0.9 9.9e-12 44.7 0.6 3.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-HIT PF04438.11 KII92751.1 - 0.01 15.4 2.0 0.01 15.4 1.4 5.2 5 1 0 5 5 5 0 HIT zinc finger RPAP2_Rtr1 PF04181.8 KII92751.1 - 0.35 10.9 22.2 1.2 9.2 0.9 4.4 4 0 0 4 4 4 0 Rtr1/RPAP2 family Metallothio_Pro PF02069.11 KII92751.1 - 1.6 8.5 26.0 0.93 9.3 1.0 4.6 5 0 0 5 5 5 0 Prokaryotic metallothionein Methyltransf_26 PF13659.1 KII92752.1 - 3.1e-13 49.7 0.0 7.9e-12 45.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII92752.1 - 8.2e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII92752.1 - 2.5e-07 31.2 0.0 9.3e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII92752.1 - 2.3e-06 27.8 0.0 3.5e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KII92752.1 - 1.7e-05 24.2 0.0 6.6e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KII92752.1 - 0.004 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KII92752.1 - 0.0044 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 KII92752.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 KII92752.1 - 0.031 14.7 0.0 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain N6_Mtase PF02384.11 KII92752.1 - 0.1 11.6 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 N-6 DNA Methylase zf-MYND PF01753.13 KII92753.1 - 1.7e-10 40.6 14.4 3.1e-10 39.7 10.0 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII92753.1 - 3.3 7.6 8.5 0.65 9.9 3.3 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 YcfA PF07927.7 KII92754.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 YcfA-like protein Topo_Zn_Ribbon PF08272.6 KII92754.1 - 0.00031 20.0 3.3 0.019 14.2 0.3 3.5 3 0 0 3 3 3 1 Topoisomerase I zinc-ribbon-like CDC45 PF02724.9 KII92754.1 - 1.6 6.6 14.8 1.2 7.0 5.3 2.7 3 0 0 3 3 3 0 CDC45-like protein PAT1 PF09770.4 KII92754.1 - 3.2 5.8 17.4 4.9 5.2 12.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cwf_Cwc_15 PF04889.7 KII92754.1 - 4.5 6.9 27.7 0.36 10.4 11.7 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF912 PF06024.7 KII92755.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mid2 PF04478.7 KII92755.1 - 0.017 14.5 0.0 0.067 12.6 0.0 2.0 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 KII92755.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 KII92755.1 - 0.06 11.6 0.0 0.18 10.0 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3185 PF11381.3 KII92755.1 - 0.1 12.3 0.7 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) TMEM169 PF15052.1 KII92756.1 - 6.7 6.6 6.8 0.23 11.3 0.6 1.6 2 0 0 2 2 2 0 TMEM169 protein family ATP_transf PF09830.4 KII92757.1 - 1e-19 70.0 0.0 2.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 KII92757.1 - 0.026 15.0 0.3 0.56 10.7 0.0 2.5 2 0 0 2 2 2 0 HIT domain DUF605 PF04652.11 KII92758.1 - 1.9 7.8 15.5 2.9 7.2 10.8 1.2 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 KII92759.1 - 8.6e-79 265.2 0.0 1.1e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KII92759.1 - 1.6e-31 109.5 0.0 2.7e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KII92759.1 - 4e-19 69.0 0.0 1e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KII92759.1 - 2.1e-12 47.5 0.0 5e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain F-box-like PF12937.2 KII92760.1 - 2.7e-08 33.3 0.1 7.8e-08 31.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII92760.1 - 0.0005 19.6 1.7 0.0032 17.0 0.0 2.5 2 0 0 2 2 2 1 F-box domain RNase_H2-Ydr279 PF09468.5 KII92761.1 - 3.3e-55 187.4 0.0 3.8e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Ribosomal_60s PF00428.14 KII92761.1 - 0.063 13.6 6.5 0.12 12.7 4.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Slu7 PF11708.3 KII92763.1 - 1e-82 277.4 15.5 1e-82 277.4 10.7 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor TRL PF13146.1 KII92763.1 - 0.026 14.4 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 TRL-like protein family zf-CCHC_4 PF14392.1 KII92763.1 - 0.046 13.3 0.7 0.095 12.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle SHOCT PF09851.4 KII92763.1 - 0.056 12.9 1.4 6.9 6.3 0.0 3.2 2 0 0 2 2 2 0 Short C-terminal domain DUF3128 PF11326.3 KII92763.1 - 0.24 11.5 4.4 0.059 13.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) BORG_CEP PF14957.1 KII92763.1 - 5.3 7.9 7.4 1 10.2 1.3 2.5 2 0 0 2 2 2 0 Cdc42 effector SNF2_N PF00176.18 KII92764.1 - 3.7e-67 226.2 0.6 6.3e-67 225.4 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KII92764.1 - 1.8e-26 92.2 5.9 3.7e-26 91.2 0.5 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KII92764.1 - 5.5e-19 67.5 8.2 1.6e-15 56.4 0.2 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KII92764.1 - 1.4e-15 56.8 0.0 3.1e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TBP PF00352.16 KII92764.1 - 0.067 12.5 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF1771 PF08590.5 KII92765.1 - 0.0018 18.2 5.6 0.0039 17.1 3.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Rabaptin PF03528.10 KII92765.1 - 0.12 12.3 0.3 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 Rabaptin DUF3918 PF13056.1 KII92765.1 - 0.5 9.7 2.5 0.46 9.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Melibiase PF02065.13 KII92767.1 - 7.9e-21 74.1 0.2 7.7e-16 57.7 0.0 2.5 1 1 1 2 2 2 2 Melibiase CBM_1 PF00734.13 KII92767.1 - 7.5e-12 44.6 12.3 7.5e-12 44.6 8.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain PH PF00169.24 KII92769.1 - 0.02 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 PH domain 2OG-FeII_Oxy_2 PF13532.1 KII92770.1 - 1.1e-19 71.0 0.0 2.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4206 PF13901.1 KII92770.1 - 0.83 9.1 3.9 1.3 8.4 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) ATP-synt_DE_N PF02823.11 KII92771.1 - 1.3e-20 72.9 0.1 1.8e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain APG6 PF04111.7 KII92772.1 - 6.3e-114 380.2 1.0 8.3e-114 379.8 0.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 FtsL PF04999.8 KII92772.1 - 0.062 13.0 2.4 0.13 11.9 1.6 1.6 1 0 0 1 1 1 0 Cell division protein FtsL DUF2564 PF10819.3 KII92772.1 - 0.33 11.0 4.9 7.6 6.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) DUF2031 PF09592.5 KII92772.1 - 0.39 9.8 4.0 0.69 9.0 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) V_ATPase_I PF01496.14 KII92772.1 - 0.7 7.6 3.2 0.91 7.3 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GCS PF03074.11 KII92773.1 - 5.6e-168 558.7 0.0 7.1e-135 449.8 0.0 2.1 1 1 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 KII92773.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Peptidase_C14 PF00656.17 KII92774.1 - 1.3e-17 64.3 0.0 1.9e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain FA_desaturase PF00487.19 KII92775.1 - 6.4e-16 58.5 19.3 6.4e-16 58.5 13.4 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KII92775.1 - 7.4e-14 51.3 0.0 1.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.26 KII92777.1 - 0.00044 20.1 0.0 0.00092 19.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Gemini_AL1 PF00799.15 KII92777.1 - 0.11 12.3 0.0 0.66 9.8 0.0 1.9 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain HTH_30 PF13556.1 KII92778.1 - 0.0032 17.0 2.4 0.0046 16.5 0.3 2.3 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_10 PF04967.7 KII92778.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_20 PF12840.2 KII92778.1 - 0.032 14.0 1.6 0.064 13.0 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain AT_hook PF02178.14 KII92778.1 - 0.08 12.6 1.7 0.14 11.9 1.2 1.4 1 0 0 1 1 1 0 AT hook motif HTH_11 PF08279.7 KII92778.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 HTH domain zf-CCHC_4 PF14392.1 KII92782.1 - 0.13 11.9 0.7 0.27 10.9 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Lipoprotein_20 PF13942.1 KII92785.1 - 0.056 12.9 0.3 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 YfhG lipoprotein CN_hydrolase PF00795.17 KII92786.1 - 2.3e-38 131.4 0.0 3.8e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase IMS PF00817.15 KII92789.1 - 2.3e-41 141.0 0.0 5.2e-41 139.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KII92789.1 - 9.4e-18 64.3 0.0 5.2e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KII92789.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Methyltransf_6 PF03737.10 KII92790.1 - 4.7e-24 85.0 0.0 6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase VanZ PF04892.7 KII92791.1 - 8.3e-07 29.0 1.7 1.9e-06 27.8 1.2 1.6 1 1 0 1 1 1 1 VanZ like family TcpE PF12648.2 KII92791.1 - 0.0008 19.5 1.5 0.0008 19.5 1.1 1.7 1 1 1 2 2 2 1 TcpE family Virul_fac_BrkB PF03631.10 KII92791.1 - 0.016 14.5 1.5 0.02 14.2 1.0 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF2339 PF10101.4 KII92791.1 - 0.03 12.6 0.6 0.037 12.3 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TauE PF01925.14 KII92791.1 - 0.073 12.5 0.9 0.17 11.2 0.7 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Phyto_Pns9_10 PF05878.6 KII92791.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF1275 PF06912.6 KII92791.1 - 1.7 7.7 6.1 2.7 7.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) zf-DNL PF05180.7 KII92792.1 - 5.8e-26 89.9 0.1 7.5e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KII92792.1 - 0.03 13.8 0.2 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger Asparaginase_2 PF01112.13 KII92793.1 - 3.2e-41 141.1 0.5 4.5e-41 140.6 0.4 1.2 1 0 0 1 1 1 1 Asparaginase SUR7 PF06687.7 KII92794.1 - 0.0058 16.2 0.4 0.0058 16.2 0.2 2.3 2 0 0 2 2 2 1 SUR7/PalI family MRP-L27 PF09809.4 KII92794.1 - 0.051 13.1 0.1 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 STE2 PF02116.10 KII92794.1 - 0.086 11.8 14.5 0.49 9.3 10.0 2.2 1 1 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR COX15-CtaA PF02628.10 KII92794.1 - 1.2 7.9 11.3 1.4 7.7 7.1 1.6 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein Tfb4 PF03850.9 KII92795.1 - 3.7e-83 278.9 0.2 4.4e-83 278.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KII92795.1 - 0.032 14.3 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-met2 PF12907.2 KII92795.1 - 1.2 9.1 9.2 2.2 8.3 0.0 3.5 3 0 0 3 3 3 0 Zinc-binding CcmD PF04995.9 KII92796.1 - 0.65 9.7 8.6 0.47 10.2 0.5 3.1 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Pyridox_oxidase PF01243.15 KII92798.1 - 4.9e-11 42.4 0.1 3.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase TRI5 PF06330.6 KII92799.1 - 4.8e-20 71.5 0.0 6.2e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KII92799.1 - 0.0033 16.6 0.0 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain adh_short PF00106.20 KII92800.1 - 1.7e-24 86.5 0.5 2.6e-24 86.0 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII92800.1 - 5.3e-14 52.2 0.1 7.3e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII92800.1 - 1.4e-09 38.1 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KII92800.1 - 0.006 15.3 0.0 0.0077 14.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tran_WecB PF03808.8 KII92800.1 - 0.041 13.2 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family ACP_syn_III PF08545.5 KII92800.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-SNAP50_C PF12251.3 KII92802.1 - 3.8e-28 98.2 0.0 6.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-TRAF PF02176.13 KII92803.1 - 4.6e-07 30.1 15.6 0.00037 20.8 2.1 3.6 1 1 3 4 4 4 4 TRAF-type zinc finger zf-Nse PF11789.3 KII92803.1 - 3.9e-06 26.2 7.9 3.9e-06 26.2 5.5 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KII92803.1 - 8.2e-06 25.5 13.1 8.2e-06 25.5 9.1 3.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII92803.1 - 0.00022 21.1 12.9 0.00022 21.1 9.0 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII92803.1 - 0.00035 20.1 13.1 0.00035 20.1 9.1 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII92803.1 - 0.0016 18.5 7.3 0.0016 18.5 5.1 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KII92803.1 - 0.0043 16.7 11.3 0.0043 16.7 7.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII92803.1 - 0.0074 15.9 11.3 0.0074 15.9 7.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII92803.1 - 0.017 14.8 9.4 0.047 13.4 6.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Sina PF03145.11 KII92803.1 - 0.059 13.0 11.3 0.21 11.2 0.9 2.8 1 1 2 3 3 3 0 Seven in absentia protein family Homeobox PF00046.24 KII92804.1 - 5.7e-16 57.8 0.0 9.8e-16 57.1 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 KII92806.1 - 4.6e-45 153.7 0.0 6.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92806.1 - 3.4e-29 101.7 0.0 4.8e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92806.1 - 0.042 12.8 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KII92806.1 - 0.042 13.5 0.7 3.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DPBB_1 PF03330.13 KII92808.1 - 1.6e-05 24.8 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Aldolase_II PF00596.16 KII92809.1 - 3.1e-33 114.9 0.0 3.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Bromodomain PF00439.20 KII92810.1 - 9.3e-24 83.1 0.1 2e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KII92810.1 - 4e-07 30.1 0.5 7.8e-07 29.1 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII92810.1 - 0.00012 22.0 0.1 0.00027 20.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family 2-Hacid_dh_C PF02826.14 KII92812.1 - 2.3e-46 157.1 0.0 3.1e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII92812.1 - 3.4e-19 68.6 0.0 4.3e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KII92812.1 - 1.7e-06 27.9 0.0 4.3e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KII92812.1 - 0.0043 17.4 0.0 0.023 15.1 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KII92812.1 - 0.021 15.3 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_U35_2 PF14550.1 KII92812.1 - 0.037 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative phage protease XkdF BAG PF02179.11 KII92813.1 - 5.2e-11 42.4 0.0 7.5e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KII92813.1 - 5.8e-06 25.6 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family PHD PF00628.24 KII92815.1 - 0.0027 17.3 1.4 0.0079 15.8 0.2 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 KII92815.1 - 0.092 12.4 0.5 0.092 12.4 0.3 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 KII92815.1 - 0.27 11.2 2.3 0.78 9.7 1.6 1.9 1 1 1 2 2 2 0 RING-like domain Pkinase PF00069.20 KII92816.1 - 1.7e-50 171.6 0.0 2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92816.1 - 7.5e-35 120.2 0.0 9.7e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92816.1 - 9.9e-07 27.9 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII92816.1 - 0.017 14.8 0.0 0.051 13.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_1 PF00133.17 KII92817.1 - 5.7e-224 744.5 0.0 9.5e-223 740.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KII92817.1 - 1.1e-28 99.8 0.1 2.8e-28 98.6 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KII92817.1 - 1.5e-16 60.0 0.1 3.9e-06 25.7 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KII92817.1 - 0.032 13.3 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.3 KII92818.1 - 2.5e-07 30.6 0.1 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII92818.1 - 1e-05 25.5 0.2 1.7e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KII92818.1 - 0.00052 19.8 4.4 0.00052 19.8 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 KII92818.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.21 KII92818.1 - 0.079 13.3 0.3 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1490 PF07371.7 KII92818.1 - 0.18 11.7 0.3 0.18 11.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1490) DUF3914 PF13053.1 KII92818.1 - 2 8.5 6.7 0.13 12.4 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3914) Atg14 PF10186.4 KII92818.1 - 2.7 6.8 11.6 0.56 9.1 0.5 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 EXS PF03124.9 KII92819.1 - 2.8e-85 286.3 3.3 3.2e-85 286.1 2.3 1.0 1 0 0 1 1 1 1 EXS family MOZ_SAS PF01853.13 KII92821.1 - 9.7e-82 272.7 0.9 1.5e-81 272.2 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KII92821.1 - 9.5e-17 60.4 0.1 2.3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KII92821.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Daxx PF03344.10 KII92821.1 - 3.6 5.9 14.7 5.3 5.4 10.2 1.2 1 0 0 1 1 1 0 Daxx Family LAG1-DNAbind PF09271.6 KII92822.1 - 2.1e-34 118.9 0.0 3.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KII92822.1 - 2e-23 82.9 0.0 2.8e-21 75.9 0.0 2.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TPR_9 PF13371.1 KII92823.1 - 0.052 13.3 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M8 PF01457.11 KII92824.1 - 0.087 11.1 0.1 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Leishmanolysin zf-GRF PF06839.7 KII92825.1 - 1.9e-08 34.0 4.0 3.5e-08 33.2 2.8 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF4200 PF13863.1 KII92825.1 - 0.026 14.4 1.1 0.047 13.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Leu_zip PF15294.1 KII92825.1 - 0.069 12.2 1.1 0.079 12.0 0.1 1.5 2 0 0 2 2 2 0 Leucine zipper CtIP_N PF10482.4 KII92825.1 - 0.14 11.9 0.8 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Mating_C PF12737.2 KII92827.1 - 0.66 8.7 6.5 0.78 8.5 4.5 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 GIY-YIG PF01541.19 KII92828.1 - 0.071 13.4 0.3 0.12 12.7 0.0 1.5 2 0 0 2 2 2 0 GIY-YIG catalytic domain Pkinase PF00069.20 KII92829.1 - 4.5e-53 180.0 0.0 1e-52 178.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92829.1 - 1.8e-22 79.6 0.0 3.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII92829.1 - 0.0003 20.5 0.0 0.0003 20.5 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII92829.1 - 0.00045 19.6 0.1 0.0012 18.2 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KII92829.1 - 0.22 11.0 3.1 0.14 11.6 0.2 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.7 KII92830.1 - 5.3e-56 189.4 0.0 5.9e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 KII92830.1 - 0.004 17.3 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KII92830.1 - 0.041 14.0 0.0 0.058 13.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BSD PF03909.12 KII92831.1 - 8.9e-20 70.1 2.0 4.7e-13 48.6 0.0 2.8 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KII92831.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain CASP_C PF08172.7 KII92832.1 - 4.7e-71 238.7 2.9 4.7e-71 238.7 2.0 3.7 3 1 1 4 4 4 1 CASP C terminal DivIVA PF05103.8 KII92832.1 - 0.0064 16.5 11.7 0.0064 16.5 8.1 6.0 4 1 2 6 6 6 3 DivIVA protein UXS1_N PF11803.3 KII92832.1 - 4.8 7.0 6.5 1.4 8.6 1.0 2.9 2 1 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal Ribosomal_S9 PF00380.14 KII92833.1 - 9.8e-34 116.2 0.4 3.5e-33 114.4 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S9/S16 BRE1 PF08647.6 KII92834.1 - 1e-12 47.8 8.2 1e-12 47.8 5.7 7.4 6 2 3 9 9 9 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KII92834.1 - 8.7e-08 32.0 12.1 1.6e-07 31.2 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII92834.1 - 6.3e-06 25.7 11.2 1.2e-05 24.8 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII92834.1 - 2.1e-05 24.0 13.2 4e-05 23.1 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII92834.1 - 4.2e-05 23.1 12.2 7.9e-05 22.3 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII92834.1 - 4.6e-05 23.1 11.0 8.7e-05 22.2 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KII92834.1 - 0.0017 18.1 3.5 0.0032 17.2 2.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KII92834.1 - 0.21 11.4 7.8 0.41 10.5 5.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 KII92834.1 - 0.3 10.9 8.4 0.16 11.8 4.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.2 KII92834.1 - 0.39 10.8 6.5 1 9.5 4.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KII92834.1 - 0.44 10.1 8.3 0.72 9.4 4.9 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Reo_sigmaC PF04582.7 KII92834.1 - 0.77 8.8 20.5 0.38 9.8 1.1 4.1 2 1 3 5 5 5 0 Reovirus sigma C capsid protein zf-RING_UBOX PF13445.1 KII92834.1 - 1.1 9.0 7.9 2.9 7.6 5.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Allantoicase PF03561.10 KII92835.1 - 5.2e-89 295.4 0.0 6.4e-44 149.0 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 KII92835.1 - 5.1e-45 152.7 0.0 7.1e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Smr PF01713.16 KII92836.1 - 0.00096 19.2 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Smr domain Transformer PF06495.6 KII92836.1 - 0.089 12.6 1.1 0.1 12.4 0.8 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Ost4 PF10215.4 KII92837.1 - 0.17 11.3 1.9 0.26 10.8 0.0 2.2 3 0 0 3 3 3 0 Oligosaccaryltransferase Baculo_PEP_C PF04513.7 KII92838.1 - 0.12 12.1 21.0 0.21 11.4 0.6 4.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bax1-I PF01027.15 KII92839.1 - 4.9e-49 166.7 26.9 5.7e-49 166.4 18.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Relaxase PF03432.9 KII92840.1 - 0.0075 15.6 2.1 11 5.2 0.0 3.1 3 0 0 3 3 3 3 Relaxase/Mobilisation nuclease domain FmrO PF07091.6 KII92841.1 - 0.017 14.0 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ten1_2 PF15490.1 KII92841.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit SCA7 PF08313.7 KII92841.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 SCA7, zinc-binding domain DUF4118 PF13493.1 KII92844.1 - 1.7 8.8 13.0 0.79 9.9 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) DUF4407 PF14362.1 KII92844.1 - 3.5 6.5 8.1 1.2 7.9 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WD40 PF00400.27 KII92845.1 - 2.5e-30 103.2 15.3 6.8e-08 32.0 0.1 6.7 7 1 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KII92845.1 - 0.0014 18.1 0.6 0.0069 15.8 0.4 2.2 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KII92845.1 - 0.0046 16.4 0.0 3.8 7.2 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat DUF3312 PF11768.3 KII92845.1 - 0.051 11.8 0.0 0.16 10.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) F-box-like PF12937.2 KII92846.1 - 3.9e-08 32.8 1.9 9.2e-08 31.6 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII92846.1 - 0.013 15.1 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 F-box domain WD40 PF00400.27 KII92846.1 - 0.2 11.6 1.9 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat LSM PF01423.17 KII92847.1 - 8.9e-14 50.7 0.3 1.2e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KII92847.1 - 0.0011 18.8 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain SNAP-25 PF00835.14 KII92849.1 - 9.3 7.1 8.8 14 6.5 0.1 3.0 2 1 1 3 3 3 0 SNAP-25 family DASH_Spc34 PF08657.5 KII92850.1 - 0.00017 21.3 8.9 0.014 15.0 0.0 3.0 2 1 0 3 3 3 2 DASH complex subunit Spc34 Syntaxin PF00804.20 KII92850.1 - 0.012 15.8 1.0 0.033 14.3 0.7 1.8 1 0 0 1 1 1 0 Syntaxin DUF342 PF03961.8 KII92850.1 - 0.11 10.8 0.7 0.16 10.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DOCK-C2 PF14429.1 KII92851.1 - 2.2e-39 134.9 0.0 4.2e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KII92851.1 - 4.5e-37 127.0 0.0 9.1e-37 126.0 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis DUF1174 PF06671.6 KII92851.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) Clusterin PF01093.12 KII92851.1 - 0.89 8.2 0.0 1.8 7.3 0.0 1.4 1 0 0 1 1 1 0 Clusterin TYA PF01021.14 KII92852.1 - 0.049 13.8 0.3 0.062 13.5 0.1 1.3 1 1 0 1 1 1 0 TYA transposon protein Alpha_kinase PF02816.13 KII92855.1 - 1.9e-14 53.7 0.0 3.4e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Alpha-kinase family Mob1_phocein PF03637.12 KII92856.1 - 4.1e-25 88.4 0.1 6.8e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Med27 PF11571.3 KII92858.1 - 3.7e-12 46.2 0.1 9.9e-12 44.8 0.1 1.7 2 0 0 2 2 2 1 Mediator complex subunit 27 Ribosomal_L22 PF00237.14 KII92858.1 - 0.055 13.4 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e TPR_11 PF13414.1 KII92859.1 - 9.7e-54 178.9 23.8 5e-10 38.8 0.0 14.6 10 5 8 18 18 18 14 TPR repeat TPR_16 PF13432.1 KII92859.1 - 4.3e-50 167.4 59.6 1.6e-10 41.3 4.0 15.2 12 3 4 16 16 16 11 Tetratricopeptide repeat TPR_1 PF00515.23 KII92859.1 - 1.2e-36 122.7 9.9 7.6e-05 22.1 0.1 14.3 15 1 0 15 15 15 7 Tetratricopeptide repeat TPR_2 PF07719.12 KII92859.1 - 1.3e-36 121.5 31.7 0.00039 20.1 0.2 18.0 19 0 0 19 19 18 8 Tetratricopeptide repeat TPR_14 PF13428.1 KII92859.1 - 2.2e-36 120.9 69.1 0.001 19.4 0.0 20.1 10 7 11 21 21 21 9 Tetratricopeptide repeat TPR_12 PF13424.1 KII92859.1 - 2.1e-25 88.4 46.4 0.0002 21.2 0.1 13.7 12 4 3 15 15 14 9 Tetratricopeptide repeat TPR_17 PF13431.1 KII92859.1 - 3.4e-25 86.0 15.6 0.0049 16.9 0.0 14.9 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 KII92859.1 - 9.4e-25 86.7 49.2 0.0089 16.3 0.7 14.8 11 3 5 16 16 16 10 Tetratricopeptide repeat TPR_8 PF13181.1 KII92859.1 - 5.7e-24 82.0 10.1 0.00061 19.3 0.0 13.5 11 2 3 14 14 14 3 Tetratricopeptide repeat TPR_9 PF13371.1 KII92859.1 - 2.5e-18 65.6 38.3 0.00025 20.8 0.1 11.1 10 1 2 12 12 12 5 Tetratricopeptide repeat Apc3 PF12895.2 KII92859.1 - 6.8e-17 61.3 1.1 5.5e-06 26.4 0.0 9.1 7 2 2 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KII92859.1 - 4.6e-16 57.2 17.8 0.018 14.8 0.0 11.8 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_6 PF13174.1 KII92859.1 - 1.6e-13 50.1 23.6 0.88 10.1 0.0 13.7 14 0 0 14 14 13 4 Tetratricopeptide repeat NARP1 PF12569.3 KII92859.1 - 0.00015 20.6 1.2 0.6 8.8 0.0 4.7 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 KII92859.1 - 0.00033 20.4 0.3 3.7 7.5 0.1 4.6 4 1 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.18 KII92859.1 - 0.00062 18.8 2.9 0.12 11.3 0.0 4.3 5 1 0 5 5 5 1 FAT domain TPR_4 PF07721.9 KII92859.1 - 0.027 14.8 39.0 3.3 8.4 0.1 11.3 12 0 0 12 12 9 0 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.1 KII92859.1 - 0.04 13.5 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RPN7 PF10602.4 KII92859.1 - 0.044 13.1 1.4 12 5.2 0.0 4.4 5 0 0 5 5 5 0 26S proteasome subunit RPN7 TPR_20 PF14561.1 KII92859.1 - 0.069 13.2 0.0 0.069 13.2 0.0 8.6 10 1 1 11 11 10 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 KII92859.1 - 0.47 9.1 2.1 3.5 6.3 0.1 2.6 3 0 0 3 3 3 0 Coatomer WD associated region Foie-gras_1 PF11817.3 KII92859.1 - 0.53 9.7 4.7 2.4 7.5 0.0 4.0 6 0 0 6 6 5 0 Foie gras liver health family 1 LETM1 PF07766.8 KII92861.1 - 2.1e-26 92.5 0.4 1.9e-14 53.3 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein Pol_alpha_B_N PF08418.5 KII92861.1 - 1.4 8.4 5.5 2.1 7.8 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Chitin_synth_2 PF03142.10 KII92862.1 - 5e-250 830.3 0.0 6.7e-250 829.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KII92862.1 - 5.8e-16 58.7 6.6 5.8e-16 58.7 4.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KII92862.1 - 1.2e-13 51.3 0.0 7.2e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KII92862.1 - 1.5e-10 40.7 0.0 5.8e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KII92862.1 - 0.00023 20.5 0.1 0.015 14.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KII92862.1 - 0.091 12.4 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.15 KII92865.1 - 1e-06 28.3 0.2 3.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII92865.1 - 3.2e-05 23.3 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KII92865.1 - 0.00013 21.4 0.1 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KII92865.1 - 0.012 15.7 0.1 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KII92865.1 - 0.093 12.9 0.1 0.33 11.1 0.2 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF3712 PF12505.3 KII92866.1 - 2.4e-107 353.8 50.2 2.4e-23 82.5 0.0 9.8 10 1 1 11 11 11 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KII92866.1 - 5.9e-12 45.8 31.5 5.9e-05 23.3 0.1 10.3 12 0 0 12 12 12 5 Late embryogenesis abundant protein GPI-anchored PF10342.4 KII92867.1 - 2.3e-09 37.5 0.5 2.9e-09 37.2 0.4 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KII92867.1 - 0.0015 18.0 0.1 0.0019 17.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) NPCBM_assoc PF10633.4 KII92867.1 - 0.015 15.2 0.5 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SNARE PF05739.14 KII92868.1 - 7.2e-12 44.8 0.0 2e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KII92868.1 - 4.7e-09 36.3 0.6 6.2e-08 32.7 0.0 2.3 2 1 0 2 2 2 1 Syntaxin Rossmann-like PF10727.4 KII92868.1 - 0.013 15.2 0.2 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain Striatin PF08232.7 KII92868.1 - 0.41 10.9 3.5 4.8 7.4 1.1 2.3 2 0 0 2 2 2 0 Striatin family WD40 PF00400.27 KII92869.1 - 1.6e-28 97.5 20.9 7.4e-12 44.6 0.2 7.3 8 0 0 8 8 6 4 WD domain, G-beta repeat NACHT PF05729.7 KII92869.1 - 8.8e-10 38.4 0.0 1.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KII92869.1 - 8.4e-07 28.1 0.0 2.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KII92869.1 - 2.9e-05 23.8 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 KII92869.1 - 0.00085 19.3 0.1 0.0073 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII92869.1 - 0.0041 17.2 0.0 0.018 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KII92869.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KII92869.1 - 0.0074 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KII92869.1 - 0.009 15.6 0.4 0.021 14.4 0.1 1.7 2 0 0 2 2 2 1 Adenylylsulphate kinase Arch_ATPase PF01637.13 KII92869.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KII92869.1 - 0.014 15.3 0.1 0.21 11.4 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KII92869.1 - 0.029 15.1 0.0 0.11 13.3 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KII92869.1 - 0.04 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PD40 PF07676.7 KII92869.1 - 0.044 13.4 5.0 63 3.3 0.0 5.9 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat ATP_bind_1 PF03029.12 KII92869.1 - 0.068 12.7 0.1 0.21 11.0 0.1 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 KII92869.1 - 0.08 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Thymidylate_kin PF02223.12 KII92869.1 - 0.13 11.5 0.2 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase Gmad1 PF10647.4 KII92869.1 - 0.42 9.9 1.8 1.7 8.0 0.1 2.7 4 1 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain BTB PF00651.26 KII92874.1 - 0.074 13.0 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Shisa PF13908.1 KII92875.1 - 0.0033 17.6 1.4 0.0076 16.4 0.0 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KII92875.1 - 0.021 13.1 0.0 0.035 12.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pro_isomerase PF00160.16 KII92877.1 - 3.8e-44 150.6 0.1 4.6e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 KII92878.1 - 3.2e-35 121.1 0.0 5.1e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KII92878.1 - 3.6e-18 64.8 0.1 6.6e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KII92878.1 - 1.8e-15 56.5 0.0 4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII92878.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PH_8 PF15409.1 KII92878.1 - 0.089 12.8 0.7 0.75 9.9 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain adh_short PF00106.20 KII92879.1 - 1.3e-14 54.5 0.7 2.1e-14 53.7 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII92879.1 - 5.9e-06 26.0 0.3 1.3e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KII92879.1 - 0.0027 17.4 0.1 0.008 15.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KII92879.1 - 0.048 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MmgE_PrpD PF03972.9 KII92881.1 - 4.6e-161 535.9 0.0 5.2e-161 535.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family adh_short PF00106.20 KII92882.1 - 5e-16 59.0 0.5 8.9e-16 58.2 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII92882.1 - 4e-05 23.3 0.4 0.00025 20.7 0.0 2.0 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KII92882.1 - 0.038 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KII92883.1 - 3.5e-16 59.5 0.1 5.6e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII92883.1 - 0.00016 21.4 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII92883.1 - 0.045 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CitX PF03802.9 KII92883.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase adh_short PF00106.20 KII92884.1 - 5.7e-17 62.1 0.1 8.8e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII92884.1 - 9.4e-07 28.6 0.1 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII92884.1 - 0.014 15.1 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KII92884.1 - 0.04 14.0 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.20 KII92885.1 - 1.2e-57 195.0 0.0 1.4e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII92885.1 - 8.1e-36 123.4 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII92885.1 - 4.4e-05 22.5 0.0 0.00013 21.0 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KII92885.1 - 0.022 13.6 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin PF08613.6 KII92886.1 - 6e-06 26.7 0.0 0.0001 22.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KII92886.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain SLT PF01464.15 KII92887.1 - 1.4e-11 43.9 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 KII92887.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysozyme-like Asp PF00026.18 KII92889.1 - 3.2e-49 167.9 10.6 7.4e-49 166.7 7.3 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII92889.1 - 8.2e-05 22.6 0.7 0.0036 17.2 0.1 2.6 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KII92889.1 - 0.011 15.2 0.0 0.48 9.9 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KII92889.1 - 0.019 15.4 2.4 13 6.3 0.0 3.4 2 1 0 2 2 2 0 Aspartyl protease Gln-synt_N PF03951.14 KII92889.1 - 0.1 12.1 0.7 0.48 10.0 0.0 2.4 3 0 0 3 3 3 0 Glutamine synthetase, beta-Grasp domain Fungal_trans_2 PF11951.3 KII92890.1 - 3.1e-42 144.5 0.4 4e-42 144.1 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII92890.1 - 4e-07 29.8 8.5 4e-07 29.8 5.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain U1snRNP70_N PF12220.3 KII92891.1 - 0.0066 16.7 0.0 0.024 14.9 0.0 2.0 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Metallophos PF00149.23 KII92892.1 - 3.3e-28 98.4 0.3 6.4e-27 94.2 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KII92892.1 - 2e-15 56.5 0.0 3.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 KII92892.1 - 0.023 14.2 0.2 0.13 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat KH_1 PF00013.24 KII92894.1 - 5.4e-78 256.5 27.0 1e-12 47.4 0.4 12.7 12 0 0 12 12 12 11 KH domain KH_3 PF13014.1 KII92894.1 - 1.5e-56 187.2 20.0 2.1e-07 30.3 0.5 11.7 11 0 0 11 11 11 10 KH domain KH_2 PF07650.12 KII92894.1 - 5.9e-10 38.5 14.4 0.082 12.4 0.0 7.0 6 0 0 6 6 6 5 KH domain SLS PF14611.1 KII92894.1 - 1.1e-05 24.9 18.9 0.91 8.9 0.0 7.2 6 4 4 10 10 10 4 Mitochondrial inner-membrane-bound regulator RRM_1 PF00076.17 KII92895.1 - 1.5e-10 40.5 0.0 2.9e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII92895.1 - 1.6e-08 34.4 0.0 7.8e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 KII92895.1 - 2e-08 33.7 0.1 4.6e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 KII92895.1 - 0.027 14.3 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 KII92896.1 - 3e-11 43.1 0.2 6.1e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII92896.1 - 1.6e-09 37.7 0.2 4.4e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII92896.1 - 2.1e-05 24.4 0.0 2.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII92896.1 - 2.2e-05 24.4 0.1 2.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII92896.1 - 3.8e-05 23.7 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII92896.1 - 0.00083 19.5 0.0 0.00096 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII92896.1 - 0.011 15.4 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein zf-C2H2_4 PF13894.1 KII92897.1 - 2.9e-10 39.7 7.1 0.00021 21.3 0.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII92897.1 - 9.6e-10 38.2 11.7 9.4e-08 31.9 0.6 3.0 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KII92897.1 - 4.5e-09 36.1 9.9 2.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KII92897.1 - 0.00076 19.5 4.1 0.13 12.4 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII92897.1 - 0.0037 17.4 3.6 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Ta0938 PF11494.3 KII92897.1 - 0.026 14.6 0.9 0.052 13.6 0.6 1.5 1 1 0 1 1 1 0 Ta0938 DUF329 PF03884.9 KII92897.1 - 0.15 11.6 2.0 0.17 11.4 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-H2C2_5 PF13909.1 KII92897.1 - 1.4 9.3 3.7 3.5 8.0 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DNA_ligase_A_M PF01068.16 KII92898.1 - 5.1e-40 136.9 0.1 1e-36 126.2 0.0 3.0 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KII92898.1 - 2.2e-39 135.0 0.0 2.9e-38 131.4 0.0 2.5 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KII92898.1 - 6.8e-17 61.6 0.0 2.3e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.1 KII92899.1 - 5.7e-29 101.0 0.0 7.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YrhK PF14145.1 KII92901.1 - 0.0016 18.0 19.4 0.58 9.8 0.0 4.5 3 1 0 3 3 3 2 YrhK-like protein BolA PF01722.13 KII92903.1 - 6.7e-29 99.6 0.4 9e-29 99.2 0.3 1.2 1 0 0 1 1 1 1 BolA-like protein RHH_3 PF12651.2 KII92903.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain zf-C2H2 PF00096.21 KII92904.1 - 1.1e-12 47.4 5.6 1.2e-06 28.5 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII92904.1 - 2.8e-09 36.7 7.6 2.6e-05 24.2 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII92904.1 - 2.9e-08 33.4 3.9 0.0012 19.0 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII92904.1 - 0.0002 21.3 0.5 0.00052 20.0 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KII92904.1 - 0.00094 18.7 0.9 0.094 12.4 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.2 KII92904.1 - 0.0065 16.6 0.6 0.0065 16.6 0.4 2.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KII92904.1 - 0.027 14.5 0.8 0.044 13.9 0.6 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KII92904.1 - 0.079 12.9 0.8 3.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 KII92904.1 - 0.12 12.5 0.2 4.3 7.5 0.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KII92904.1 - 0.26 11.2 2.1 4.9 7.1 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KII92904.1 - 0.78 9.5 3.8 0.56 10.0 0.2 2.2 2 0 0 2 2 2 0 BED zinc finger Pkinase PF00069.20 KII92905.1 - 2e-57 194.2 0.1 2.5e-38 131.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII92905.1 - 1.3e-24 86.6 0.3 2.2e-16 59.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KII92905.1 - 2.7e-05 23.2 0.0 0.00024 20.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KII92905.1 - 0.0066 16.2 0.5 0.023 14.4 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KII92905.1 - 0.017 15.6 0.0 0.057 13.9 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KII92905.1 - 0.088 11.5 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase VP4_haemagglut PF00426.13 KII92905.1 - 0.29 9.0 0.6 0.41 8.5 0.4 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Homeobox PF00046.24 KII92906.1 - 2.6e-16 58.9 3.4 4.5e-16 58.1 2.4 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KII92906.1 - 0.0066 16.1 0.2 0.0066 16.1 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain ABC_tran PF00005.22 KII92907.1 - 1.7e-46 157.9 0.0 8.6e-28 97.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII92907.1 - 6.7e-16 59.0 0.5 0.0048 16.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KII92907.1 - 4.1e-12 45.8 0.0 4.4e-05 22.8 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 KII92907.1 - 4.4e-09 35.8 0.1 8.2e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 KII92907.1 - 6.9e-07 30.1 0.0 0.041 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KII92907.1 - 1e-06 29.2 0.0 0.01 16.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KII92907.1 - 1.1e-06 28.0 1.0 0.043 13.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KII92907.1 - 2.5e-06 27.4 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KII92907.1 - 4.3e-05 22.7 0.1 0.033 13.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KII92907.1 - 6e-05 23.4 0.1 0.08 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII92907.1 - 6e-05 23.1 1.9 2.8 7.9 0.0 4.5 5 0 0 5 5 4 1 AAA ATPase domain DUF87 PF01935.12 KII92907.1 - 6.2e-05 22.9 0.6 0.25 11.1 0.0 2.9 3 0 0 3 3 2 2 Domain of unknown function DUF87 AAA_28 PF13521.1 KII92907.1 - 0.0001 22.3 0.0 0.43 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KII92907.1 - 0.00011 22.2 0.0 0.65 10.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KII92907.1 - 0.00015 21.6 0.0 0.24 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KII92907.1 - 0.00019 21.1 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KII92907.1 - 0.00021 20.1 0.3 0.074 11.8 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 KII92907.1 - 0.00029 20.3 0.6 0.75 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 KII92907.1 - 0.00038 20.7 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KII92907.1 - 0.00064 19.4 0.1 0.26 10.9 0.0 3.3 4 0 0 4 4 3 1 NACHT domain AAA_25 PF13481.1 KII92907.1 - 0.001 18.5 0.2 17 4.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.1 KII92907.1 - 0.0025 17.7 0.0 0.82 9.6 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KII92907.1 - 0.0072 14.8 0.0 1.1 7.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII92907.1 - 0.0077 16.3 0.1 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase HEAT PF02985.17 KII92907.1 - 0.0083 16.1 8.2 5 7.4 0.0 5.0 5 0 0 5 5 3 0 HEAT repeat AAA_30 PF13604.1 KII92907.1 - 0.013 15.0 0.3 11 5.5 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_14 PF13173.1 KII92907.1 - 0.017 15.0 0.1 9.6 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 KII92907.1 - 0.018 14.8 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 KII92907.1 - 0.019 14.6 0.2 16 5.1 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase AAA_15 PF13175.1 KII92907.1 - 0.023 13.7 0.0 10 5.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 KII92907.1 - 0.032 13.7 0.2 9.5 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KII92907.1 - 0.036 13.5 0.1 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KII92907.1 - 0.05 13.0 0.1 5.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adaptin_N PF01602.15 KII92907.1 - 0.053 11.8 0.1 0.16 10.2 0.1 1.7 2 0 0 2 2 2 0 Adaptin N terminal region cobW PF02492.14 KII92907.1 - 0.096 12.1 0.3 12 5.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 KII92907.1 - 0.1 11.9 0.0 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 MutS domain V G-alpha PF00503.15 KII92907.1 - 0.11 11.1 0.2 0.33 9.5 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.22 KII92907.1 - 0.13 11.7 0.0 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HEAT_EZ PF13513.1 KII92907.1 - 0.2 12.1 19.7 2 8.9 0.2 5.6 4 1 2 6 6 5 0 HEAT-like repeat AAA_24 PF13479.1 KII92907.1 - 0.22 11.1 1.0 10 5.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KII92907.1 - 0.26 8.5 1.9 3.1 5.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Herpes_gE PF02480.11 KII92908.1 - 0.054 11.7 0.1 0.094 10.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PgaD PF13994.1 KII92908.1 - 0.094 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein MLANA PF14991.1 KII92908.1 - 0.25 11.3 3.1 0.2 11.6 0.3 2.1 1 1 1 2 2 2 0 Protein melan-A Glyco_hydro_18 PF00704.23 KII92909.1 - 1.5e-95 320.5 3.7 1.7e-95 320.3 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KII92909.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Kinesin-relat_1 PF12711.2 KII92910.1 - 0.045 14.1 3.2 0.09 13.1 2.2 1.5 1 0 0 1 1 1 0 Kinesin motor DUF972 PF06156.8 KII92910.1 - 0.45 10.8 5.1 1 9.7 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF724 PF05266.9 KII92910.1 - 0.79 9.3 8.0 1.6 8.3 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.8 KII92910.1 - 4 6.4 5.1 5.8 5.8 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Striatin PF08232.7 KII92910.1 - 5.8 7.2 15.4 0.23 11.7 5.3 2.2 2 0 0 2 2 2 0 Striatin family GTP_EFTU PF00009.22 KII92911.1 - 6.6e-23 81.1 0.0 6.5e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KII92911.1 - 1.5e-16 60.3 0.0 4.1e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KII92911.1 - 7e-08 32.4 4.7 8.3e-08 32.2 0.6 3.1 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII92911.1 - 0.048 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KII92911.1 - 0.051 13.2 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UDPG_MGDP_dh_N PF03721.9 KII92911.1 - 0.082 12.2 0.0 6.9 6.0 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GTP_EFTU_D4 PF14578.1 KII92911.1 - 0.1 12.2 0.5 0.36 10.5 0.3 1.9 1 1 0 1 1 1 0 Elongation factor Tu domain 4 zf-RING_2 PF13639.1 KII92912.1 - 3.7e-11 42.6 2.0 3.5e-09 36.3 0.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KII92912.1 - 7.6e-07 29.1 2.2 8.7e-06 25.7 1.5 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KII92912.1 - 1.3e-06 28.2 3.0 1.9e-06 27.7 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII92912.1 - 1.3e-06 27.8 0.2 1.1e-05 24.9 0.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII92912.1 - 2.8e-05 23.7 1.1 4.2e-05 23.1 0.1 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII92912.1 - 0.00099 18.7 0.5 0.00099 18.7 0.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII92912.1 - 0.0025 17.6 1.2 0.0042 16.9 0.2 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KII92912.1 - 0.13 11.7 0.5 0.46 10.0 0.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KII92912.1 - 0.17 11.5 0.1 0.46 10.1 0.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KII92912.1 - 0.24 11.3 3.3 0.17 11.7 0.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII92912.1 - 0.44 10.2 5.6 0.069 12.8 0.3 2.2 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 KII92912.1 - 0.73 9.8 4.2 1.2 9.1 1.6 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain NKAIN PF05640.9 KII92912.1 - 5.4 5.9 7.0 4.8 6.0 3.1 1.9 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein DUF3533 PF12051.3 KII92913.1 - 2.5e-97 326.0 13.2 3.1e-97 325.7 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 KII92913.1 - 3.4e-10 39.4 20.4 4.9e-10 38.9 14.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 KII92913.1 - 1.3 8.0 32.1 3.8 6.6 22.2 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Ferrochelatase PF00762.14 KII92915.1 - 5.7e-98 327.7 0.0 6.5e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase GHMP_kinases_N PF00288.21 KII92916.1 - 6.1e-10 39.0 1.4 6.1e-10 39.0 1.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KII92916.1 - 7.2e-05 22.9 0.0 0.00024 21.2 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.13 KII92917.1 - 3e-66 223.6 25.5 3.4e-66 223.4 17.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 KII92919.1 - 1.6e-35 122.4 37.0 1.6e-35 122.4 25.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MS_channel PF00924.13 KII92920.1 - 2.2e-14 53.2 4.0 2.2e-14 53.2 2.8 2.1 2 1 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KII92920.1 - 0.02 14.1 0.3 0.053 12.8 0.2 1.8 1 0 0 1 1 1 0 EF hand Fe_hyd_lg_C PF02906.9 KII92921.1 - 1.7e-69 234.2 0.0 2.7e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Omptin PF01278.15 KII92921.1 - 0.0094 15.0 1.5 0.015 14.3 1.0 1.2 1 0 0 1 1 1 1 Omptin family GATase_7 PF13537.1 KII92922.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain HhH-GPD PF00730.20 KII92925.1 - 6.1e-11 42.5 0.0 7.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF1115 PF06544.7 KII92927.1 - 0.00012 21.7 0.0 0.00013 21.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.13 KII92927.1 - 0.044 13.8 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Acylphosphatase Man-6-P_recep PF02157.10 KII92928.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor zf-LYAR PF08790.6 KII92928.1 - 0.4 10.4 3.3 1.1 8.9 2.3 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Cortex-I_coil PF09304.5 KII92929.1 - 0.038 14.0 0.9 0.044 13.8 0.6 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil Tet_JBP PF12851.2 KII92930.1 - 3.5e-07 29.6 0.0 4.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF3956 PF13104.1 KII92931.1 - 0.95 9.0 3.7 0.92 9.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3956) PIRT PF15099.1 KII92931.1 - 2.8 7.1 5.6 2.7 7.2 3.9 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3624 PF12292.3 KII92931.1 - 3 8.3 5.0 5.6 7.4 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) Peptidase_U4 PF03419.8 KII92932.1 - 1.6 7.7 6.8 1.7 7.6 4.7 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF3527 PF12043.3 KII92933.1 - 0.14 11.6 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) ArgJ PF01960.13 KII92934.1 - 1.9e-14 52.8 0.0 2.5e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Zn_clus PF00172.13 KII92939.1 - 4.5e-09 36.0 12.3 8.4e-09 35.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.5 KII92939.1 - 3.2 5.9 10.3 4 5.5 7.1 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.4 KII92939.1 - 3.6 5.7 5.8 4.2 5.5 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein MMtag PF10159.4 KII92943.1 - 5.6e-31 106.4 2.2 5.6e-31 106.4 1.5 3.2 3 1 0 3 3 3 1 Kinase phosphorylation protein SAE2 PF08573.5 KII92943.1 - 0.035 14.8 10.3 0.035 14.8 7.2 3.1 3 1 1 4 4 4 0 DNA repair protein endonuclease SAE2/CtIP C-terminus MIP-T3 PF10243.4 KII92943.1 - 3.5 5.9 27.6 4.3 5.6 19.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PWWP PF00855.12 KII92944.1 - 4.3e-17 62.0 2.2 6.7e-17 61.4 0.0 2.4 1 1 1 2 2 2 1 PWWP domain DUF3083 PF11281.3 KII92944.1 - 0.041 12.9 0.1 0.42 9.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3083) DUF566 PF04484.7 KII92944.1 - 9.6 5.6 13.2 17 4.7 9.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) BCS1_N PF08740.6 KII92945.1 - 2.3e-25 89.3 3.1 2.3e-25 89.3 2.1 2.2 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KII92945.1 - 7.6e-15 55.2 0.0 3.8e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KII92945.1 - 0.00016 21.1 0.2 0.021 14.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KII92945.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 KII92945.1 - 0.0064 15.4 0.0 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KII92945.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KII92945.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KII92945.1 - 0.05 14.4 6.3 0.064 14.0 0.0 3.2 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.22 KII92945.1 - 0.086 13.1 4.6 0.16 12.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Astro_capsid PF03115.9 KII92945.1 - 0.26 9.5 8.4 11 4.1 5.3 2.2 2 0 0 2 2 2 0 Astrovirus capsid protein precursor FtsK_SpoIIIE PF01580.13 KII92945.1 - 0.51 9.7 4.0 8.8 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KII92945.1 - 0.58 10.4 17.5 14 5.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain MBOAT_2 PF13813.1 KII92946.1 - 4.1e-17 62.0 2.4 4.1e-17 62.0 1.7 3.4 3 1 0 3 3 3 1 Membrane bound O-acyl transferase family TFIIS_C PF01096.13 KII92948.1 - 0.023 14.3 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) LVIVD PF08309.6 KII92948.1 - 0.048 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 LVIVD repeat Sec2p PF06428.6 KII92949.1 - 3.2e-09 36.5 13.3 3.2e-09 36.5 9.2 2.6 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p AAA_23 PF13476.1 KII92949.1 - 0.46 10.7 5.7 0.65 10.2 1.2 2.2 2 0 0 2 2 2 0 AAA domain SET PF00856.23 KII92950.1 - 5.2e-10 39.8 0.1 5.2e-10 39.8 0.0 3.6 2 2 0 2 2 2 1 SET domain Ribosomal_S8e PF01201.17 KII92951.1 - 1e-51 174.5 1.2 1.3e-51 174.1 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e UDPGP PF01704.13 KII92952.1 - 8.8e-182 604.2 1.8 1e-181 604.0 1.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDPGP PF01704.13 KII92953.1 - 3.9e-181 602.1 1.0 4.5e-181 601.9 0.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Metallophos PF00149.23 KII92954.1 - 1.8e-07 30.7 0.8 3.7e-07 29.7 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NADH_B2 PF14813.1 KII92955.1 - 0.072 12.7 0.2 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Cytochrome_CBB3 PF13442.1 KII92957.1 - 0.018 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.5 KII92957.1 - 0.046 13.2 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) ABM PF03992.11 KII92958.1 - 1.9e-06 27.7 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AJAP1_PANP_C PF15298.1 KII92960.1 - 1.6 8.5 11.4 2.3 8.0 7.9 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Sporozoite_P67 PF05642.6 KII92960.1 - 6.4 4.5 21.6 7.6 4.2 15.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Polyoma_coat2 PF00761.15 KII92960.1 - 7.1 6.0 12.9 9.8 5.5 8.9 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein DUF2348 PF09807.4 KII92961.1 - 5.6e-15 55.1 0.1 1.5e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Sec34 PF04136.10 KII92962.1 - 7e-29 100.5 0.0 1.6e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Sec34-like family FUSC PF04632.7 KII92962.1 - 0.14 10.5 3.0 0.094 11.1 0.2 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family DIOX_N PF14226.1 KII92963.1 - 8.9e-27 93.9 0.0 1.6e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII92963.1 - 8.4e-18 64.4 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oscp1 PF10188.4 KII92966.1 - 0.055 13.2 0.1 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Organic solute transport protein 1 Dimer_Tnp_hAT PF05699.9 KII92967.1 - 0.0013 18.3 0.2 0.0025 17.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.11 KII92968.1 - 1.2e-15 57.1 28.9 1.7e-15 56.6 20.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KII92968.1 - 4.9e-07 29.3 1.7 4.9e-07 29.3 1.2 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Cpn60_TCP1 PF00118.19 KII92969.1 - 8.2e-148 493.0 0.0 1e-147 492.7 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short_C2 PF13561.1 KII92970.1 - 1e-30 107.2 0.7 1.2e-30 107.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII92970.1 - 6.5e-28 97.7 0.4 9.1e-28 97.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII92970.1 - 1.2e-12 47.8 0.6 5.2e-12 45.8 0.4 1.8 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 KII92970.1 - 0.0011 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII92970.1 - 0.048 14.1 0.0 0.66 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 KII92971.1 - 3.9e-07 29.6 0.0 2.2e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII92971.1 - 0.028 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF3302 PF11742.3 KII92971.1 - 0.081 12.7 1.8 0.23 11.3 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) BSD PF03909.12 KII92972.1 - 9.9e-10 38.0 1.0 1.9e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 BSD domain DUF4456 PF14644.1 KII92972.1 - 0.0095 15.1 0.7 0.65 9.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) DinB_2 PF12867.2 KII92972.1 - 0.013 15.7 2.2 2.2 8.6 0.0 3.0 3 1 0 3 3 3 0 DinB superfamily DUF2277 PF10041.4 KII92972.1 - 0.036 14.0 1.5 0.88 9.5 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) DUF883 PF05957.8 KII92972.1 - 0.037 14.4 4.4 2.6 8.5 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4019 PF13211.1 KII92972.1 - 0.1 12.8 1.1 6.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) ATP-synt_B PF00430.13 KII92972.1 - 4.9 6.9 9.7 6.5 6.5 0.7 2.8 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) CPSase_sm_chain PF00988.17 KII92973.1 - 9e-45 151.3 0.0 1.3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KII92973.1 - 6.9e-37 126.7 0.0 9.2e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KII92973.1 - 2.3e-08 33.7 0.1 4.6e-07 29.4 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KII92973.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Scs3p PF10261.4 KII92974.1 - 6.7e-41 139.8 9.8 4.2e-39 134.0 6.8 2.3 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Glyco_hydro_38 PF01074.17 KII92975.1 - 2.3e-80 269.7 0.1 3.6e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KII92975.1 - 5.5e-62 210.0 0.0 7.6e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KII92975.1 - 1.1e-25 89.5 0.0 2.2e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Aldedh PF00171.17 KII92976.1 - 3.6e-80 269.5 0.0 4.4e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 KII92976.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Fic/DOC family ALAD PF00490.16 KII92977.1 - 1.5e-119 398.7 0.0 1.8e-119 398.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Aldedh PF00171.17 KII92978.1 - 8.4e-79 265.0 0.0 1e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 KII92978.1 - 0.04 14.5 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family Aldedh PF00171.17 KII92979.1 - 9.7e-85 284.6 0.0 1.3e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PRCC PF10253.4 KII92979.1 - 0.16 12.6 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Shisa PF13908.1 KII92981.1 - 2.3e-07 31.1 0.4 3.6e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.3 KII92981.1 - 3.9e-07 30.6 5.8 5.8e-07 30.1 4.0 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4448 PF14610.1 KII92981.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.10 KII92981.1 - 0.027 14.0 4.7 0.043 13.3 3.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 m04gp34like PF12216.3 KII92981.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Immune evasion protein Herpes_gE PF02480.11 KII92981.1 - 0.096 10.9 0.2 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SLA_LP_auto_ag PF05889.8 KII92981.1 - 0.14 10.5 0.1 0.18 10.2 0.1 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cyt-b5 PF00173.23 KII92983.1 - 1.5e-07 31.0 0.1 0.0011 18.6 0.1 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain G-alpha PF00503.15 KII92984.1 - 1e-129 432.6 0.1 1.2e-129 432.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII92984.1 - 1.5e-16 60.1 1.2 9.3e-12 44.5 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KII92984.1 - 0.00026 21.4 0.5 0.18 12.3 0.0 2.9 3 1 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 KII92984.1 - 0.00034 19.8 2.8 0.0074 15.4 0.0 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KII92984.1 - 0.0044 16.4 0.0 5.9 6.2 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII92984.1 - 0.017 15.0 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KII92984.1 - 0.025 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.15 KII92984.1 - 0.028 13.9 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 KII92984.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family FAR1 PF03101.10 KII92985.1 - 1.1 9.7 5.8 2.1 8.8 4.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain GNVR PF13807.1 KII92987.1 - 0.51 10.1 2.4 1.3 8.8 0.1 2.7 1 1 2 3 3 3 0 G-rich domain on putative tyrosine kinase DUF2009 PF09418.5 KII92987.1 - 4.5 5.9 8.0 0.32 9.7 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) EURL PF06937.6 KII92989.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 EURL protein HrpB7 PF09486.5 KII92990.1 - 0.0091 15.9 4.6 0.0091 15.9 3.2 1.8 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) COG2 PF06148.6 KII92990.1 - 0.048 13.5 0.2 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DLH PF01738.13 KII92995.1 - 9.4e-26 90.4 0.1 1.1e-25 90.2 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII92995.1 - 1.4e-07 31.3 0.3 2.1e-07 30.7 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII92995.1 - 2.2e-05 24.4 1.6 0.026 14.4 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family COX7C PF02935.11 KII92995.1 - 0.16 11.7 0.4 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DUF4598 PF15370.1 KII92996.1 - 2.8e-18 66.2 2.9 2.8e-18 66.2 2.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Nop14 PF04147.7 KII92996.1 - 0.092 10.6 4.7 0.098 10.5 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family EBV-NA3 PF05009.7 KII92996.1 - 0.4 9.9 2.0 0.53 9.4 1.4 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF572 PF04502.8 KII92996.1 - 1 8.5 5.7 0.14 11.3 1.4 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) ANAPC15 PF15243.1 KII92996.1 - 1.7 8.7 8.6 32 4.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 CDC45 PF02724.9 KII92996.1 - 1.8 6.5 6.5 2.4 6.0 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 KII92996.1 - 3.7 7.1 14.4 5.5 6.6 10.0 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dus PF01207.12 KII92997.1 - 7.1e-83 277.9 0.0 2.6e-73 246.5 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 KII92997.1 - 0.00029 20.5 0.0 0.03 13.9 0.0 2.3 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.10 KII92997.1 - 0.00069 18.8 0.3 0.01 14.9 0.0 2.6 2 1 1 3 3 3 1 Nitronate monooxygenase ThiG PF05690.9 KII92997.1 - 0.002 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG tRNA-synt_2b PF00587.20 KII92997.1 - 0.0024 17.4 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) DUF2690 PF10901.3 KII92997.1 - 0.022 14.7 1.4 8.9 6.3 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2690) His_biosynth PF00977.16 KII92997.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ApbA_C PF08546.6 KII92998.1 - 1.9e-20 73.1 0.0 6e-18 65.0 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KII92998.1 - 8.6e-18 64.2 0.0 1.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KII92998.1 - 0.0091 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.14 KII92998.1 - 0.14 11.2 0.1 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA_C PF08546.6 KII92999.1 - 1.9e-19 69.8 0.0 3.7e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KII92999.1 - 3.1e-16 59.1 0.0 4.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 KII92999.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 KII92999.1 - 0.13 12.1 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 ThiF family ubiquitin PF00240.18 KII93000.1 - 3.4e-19 68.0 0.3 5.5e-19 67.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KII93000.1 - 4.5e-11 42.2 0.1 1.1e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KII93000.1 - 7.4e-11 41.5 0.6 1.2e-10 40.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KII93000.1 - 7.6e-07 29.2 0.1 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain XPC-binding PF09280.6 KII93000.1 - 6.4e-05 22.3 10.1 0.0042 16.5 3.9 3.6 2 1 2 4 4 4 2 XPC-binding domain Rad60-SLD_2 PF13881.1 KII93000.1 - 0.015 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 KII93000.1 - 0.052 13.0 2.2 0.2 11.1 0.0 2.5 2 0 0 2 2 2 0 CUE domain C2 PF00168.25 KII93001.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain Pkinase PF00069.20 KII93004.1 - 2.2e-06 27.0 0.0 3.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93004.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 KII93004.1 - 0.012 15.3 1.1 0.029 14.0 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family AhpC-TSA_2 PF13911.1 KII93005.1 - 9.5e-24 83.5 0.0 1.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KII93005.1 - 1.6e-08 34.2 0.0 2.3e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII93005.1 - 7.3e-08 32.0 0.0 2.3e-07 30.4 0.0 1.6 1 1 1 2 2 2 1 Redoxin Pkinase PF00069.20 KII93007.1 - 3e-74 249.4 0.0 4e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93007.1 - 8.4e-39 133.1 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93007.1 - 4.5e-06 25.8 0.0 9.6e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like UBA_2 PF08587.6 KII93007.1 - 5.4e-05 23.3 0.5 0.00011 22.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 KII93007.1 - 0.00082 18.7 0.1 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KII93007.1 - 0.007 16.1 1.9 0.18 11.4 0.2 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Aft1_OSA PF11785.3 KII93007.1 - 0.053 14.0 0.7 0.11 13.0 0.5 1.6 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Kdo PF06293.9 KII93007.1 - 0.084 11.9 0.1 0.38 9.7 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Heme_oxygenase PF01126.15 KII93008.1 - 0.017 14.6 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Heme oxygenase DUF4515 PF14988.1 KII93008.1 - 0.1 12.2 13.7 0.054 13.1 6.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4515) CCDC155 PF14662.1 KII93008.1 - 0.17 11.4 13.4 0.036 13.6 4.5 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 ATG16 PF08614.6 KII93008.1 - 0.42 10.3 12.1 0.12 12.1 5.8 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_S46 PF10459.4 KII93008.1 - 1.6 7.0 6.4 0.21 9.9 1.5 1.6 2 0 0 2 2 2 0 Peptidase S46 DUF572 PF04502.8 KII93008.1 - 2.1 7.4 5.8 3.5 6.7 4.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) SLX9 PF15341.1 KII93008.1 - 5.3 7.5 9.5 0.52 10.7 3.0 1.8 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 HNH_2 PF13391.1 KII93009.1 - 2.5e-07 30.3 0.0 5.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3071 PF11268.3 KII93009.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) WD40 PF00400.27 KII93010.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat HNH_2 PF13391.1 KII93012.1 - 1.1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3071 PF11268.3 KII93012.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) SRP14 PF02290.10 KII93013.1 - 1.4e-22 79.3 1.0 5.3e-22 77.5 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle 14kD protein Adeno_VII PF03228.9 KII93013.1 - 1 9.9 10.3 1.4 9.5 7.2 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII zf-C3HC4_3 PF13920.1 KII93014.1 - 4e-05 23.1 10.8 6.8e-05 22.4 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII93014.1 - 0.012 15.2 12.6 0.02 14.6 8.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Med9 PF07544.8 KII93014.1 - 0.02 14.5 4.9 0.031 13.9 3.4 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF812 PF05667.6 KII93014.1 - 0.073 11.5 4.6 0.094 11.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3373 PF11853.3 KII93014.1 - 0.083 11.4 0.1 0.092 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3450 PF11932.3 KII93014.1 - 0.15 11.3 7.4 0.21 10.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF641 PF04859.7 KII93014.1 - 0.16 11.7 4.4 0.22 11.2 3.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-RING_2 PF13639.1 KII93014.1 - 0.17 11.7 13.6 0.3 10.9 9.4 1.4 1 0 0 1 1 1 0 Ring finger domain DUF4200 PF13863.1 KII93014.1 - 0.21 11.5 11.3 0.3 11.0 7.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) zf-C3HC4_2 PF13923.1 KII93014.1 - 3.6 7.7 13.1 7.3 6.7 9.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII93014.1 - 4.7 6.8 9.4 8.8 5.9 6.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nramp PF01566.13 KII93016.1 - 7.1e-87 291.5 26.5 7.1e-87 291.5 18.4 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein PsaL PF02605.10 KII93016.1 - 0.027 14.0 2.5 0.04 13.4 0.1 2.4 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI EthD PF07110.6 KII93017.1 - 1.3e-12 48.4 0.0 1.6e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 EthD domain DUF4543 PF15076.1 KII93017.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Histone PF00125.19 KII93018.1 - 4.1e-30 103.7 0.8 6.6e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII93018.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KII93018.1 - 0.0013 18.7 0.1 0.0013 18.7 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KII93018.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KII93018.1 - 0.14 11.3 1.5 0.17 11.1 1.0 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T TAF4 PF05236.9 KII93018.1 - 1.7 7.8 7.4 4.1 6.5 0.1 2.0 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family EthD PF07110.6 KII93019.1 - 2.2e-14 54.1 0.0 2.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 EthD domain EthD PF07110.6 KII93020.1 - 1.3e-17 64.5 0.0 1.7e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 EthD domain MOZART2 PF12926.2 KII93020.1 - 0.16 11.6 0.5 1.4 8.5 0.2 2.5 1 1 1 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF726 PF05277.7 KII93021.1 - 1.4e-122 408.8 1.1 2.1e-122 408.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KII93021.1 - 0.00075 19.2 0.4 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII93021.1 - 0.019 14.5 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1115 PF06544.7 KII93023.1 - 1.2e-08 34.6 0.5 1.9e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.13 KII93023.1 - 0.026 14.6 0.1 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Acylphosphatase RRM_1 PF00076.17 KII93024.1 - 7.4e-19 67.1 0.0 8.1e-19 67.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII93024.1 - 1.6e-16 60.0 0.0 1.8e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII93024.1 - 3e-11 43.0 0.0 4.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KII93024.1 - 0.036 13.7 0.0 3.2 7.4 0.0 2.0 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.6 KII93024.1 - 0.049 13.1 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain RRM_3 PF08777.6 KII93024.1 - 0.066 13.0 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif F-box-like PF12937.2 KII93025.1 - 0.026 14.2 3.7 0.062 13.0 2.6 1.7 1 0 0 1 1 1 0 F-box-like Peptidase_M17 PF00883.16 KII93026.1 - 2.4e-113 378.1 0.0 3e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KII93026.1 - 9.1e-09 35.1 0.2 2e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain F-box-like PF12937.2 KII93029.1 - 0.003 17.2 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 F-box-like DUF1296 PF06972.6 KII93030.1 - 0.044 13.7 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) HNH_2 PF13391.1 KII93031.1 - 2.8e-08 33.4 0.0 5.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF3071 PF11268.3 KII93031.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) F-box-like PF12937.2 KII93032.1 - 6.4e-06 25.7 1.8 0.00053 19.6 0.5 3.1 2 1 0 2 2 2 2 F-box-like F-box-like PF12937.2 KII93033.1 - 0.0012 18.5 0.5 0.0018 17.9 0.1 1.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KII93034.1 - 0.013 15.1 2.2 3.2 7.4 0.1 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KII93035.1 - 4.7e-06 26.2 0.3 1.5e-05 24.6 0.2 2.0 1 1 0 1 1 1 1 F-box-like Amidohydro_1 PF01979.15 KII93036.1 - 1.1e-15 58.1 0.2 4.7e-15 56.0 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KII93036.1 - 5.3e-09 35.7 0.2 1.4e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KII93036.1 - 2e-05 24.7 2.9 8.5e-05 22.7 1.0 2.6 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KII93036.1 - 3.6e-05 23.1 0.8 0.02 14.1 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family PUF PF00806.14 KII93039.1 - 2.5e-28 95.9 0.2 1.7e-07 30.3 0.0 6.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat F-box-like PF12937.2 KII93040.1 - 1.4e-07 31.1 0.9 2.3e-05 24.0 0.2 3.0 2 1 0 2 2 2 2 F-box-like AraC_binding_2 PF14525.1 KII93041.1 - 0.014 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 AraC-binding-like domain Pkinase PF00069.20 KII93042.1 - 4.8e-12 45.5 0.0 1.2e-11 44.2 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93042.1 - 0.00018 20.6 0.0 0.00039 19.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII93044.1 - 3.2e-10 39.5 0.0 3.6e-09 36.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93044.1 - 0.025 13.6 0.0 0.12 11.4 0.0 2.2 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KII93045.1 - 1.9e-12 46.8 0.0 1.5e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93045.1 - 0.00032 19.8 0.0 0.002 17.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII93045.1 - 0.053 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ER PF01133.12 KII93045.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Enhancer of rudimentary Pkinase PF00069.20 KII93046.1 - 2e-08 33.6 0.0 1.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93046.1 - 0.012 14.6 0.1 0.032 13.3 0.1 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase GATA PF00320.22 KII93047.1 - 0.021 14.1 2.7 0.36 10.2 0.2 2.2 2 0 0 2 2 2 0 GATA zinc finger zf-C2H2_3 PF13878.1 KII93047.1 - 0.036 13.6 0.1 5.1 6.7 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF2752 PF10825.3 KII93047.1 - 0.14 12.1 0.9 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Rpr2 PF04032.11 KII93047.1 - 0.24 11.3 1.2 0.29 11.0 0.3 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase PF00069.20 KII93048.1 - 1.1e-11 44.3 0.0 1.9e-10 40.3 0.0 2.0 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93048.1 - 0.00022 20.3 0.0 0.0015 17.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII93048.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF656 PF04920.7 KII93052.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF656) Pkinase PF00069.20 KII93054.1 - 3.3e-13 49.3 0.0 1.2e-10 40.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93054.1 - 0.00035 19.7 0.0 0.0023 17.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII93056.1 - 4.1e-12 45.7 0.0 4.8e-11 42.3 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Glutaredoxin PF00462.19 KII93057.1 - 4.3e-19 68.2 0.1 5.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KII93057.1 - 5e-05 23.0 0.0 6.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 KII93057.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 KII93057.1 - 0.0042 17.3 0.0 0.0065 16.6 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 KII93057.1 - 0.015 15.3 0.3 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 KII93057.1 - 0.015 15.4 0.3 0.047 13.8 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.15 KII93057.1 - 0.053 13.0 0.6 0.74 9.3 0.1 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain GST_N_3 PF13417.1 KII93057.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pkinase PF00069.20 KII93058.1 - 9.7e-05 21.6 0.0 0.0021 17.2 0.0 2.8 3 1 1 4 4 4 1 Protein kinase domain Pkinase PF00069.20 KII93060.1 - 5.6e-13 48.6 0.0 1e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93060.1 - 0.0078 15.3 0.0 0.089 11.8 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII93061.1 - 1.1e-10 41.0 0.0 2e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.20 KII93063.1 - 2.8e-13 49.6 0.0 1.4e-11 44.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93063.1 - 0.063 12.3 0.0 0.19 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KII93064.1 - 1.1e-10 41.1 0.0 2e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.20 KII93066.1 - 4.3e-14 52.3 0.0 2.9e-13 49.5 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93066.1 - 8.4e-05 21.7 0.0 0.00044 19.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII93067.1 - 7.9e-12 44.8 0.0 9.8e-11 41.2 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93067.1 - 0.0075 15.3 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII93068.1 - 7.5e-05 22.0 0.0 0.0017 17.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain NIF3 PF01784.13 KII93069.1 - 8.9e-58 195.7 0.0 1.1e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PfkB PF00294.19 KII93069.1 - 0.038 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase FAD_binding_3 PF01494.14 KII93071.1 - 8.6e-34 117.1 0.5 1.3e-33 116.4 0.1 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KII93072.1 - 3e-10 39.6 0.2 3e-10 39.6 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KII93072.1 - 1.8e-06 27.8 0.1 2.2e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KII93072.1 - 1.2e-05 24.4 0.1 1.3e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KII93072.1 - 0.0001 21.2 0.2 0.0001 21.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KII93072.1 - 0.00026 19.6 0.2 0.00026 19.6 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KII93072.1 - 0.00048 20.0 0.1 0.00048 20.0 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KII93072.1 - 0.00071 19.6 0.1 0.00071 19.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII93072.1 - 0.00072 18.5 0.1 0.00072 18.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KII93072.1 - 0.001 18.0 0.4 0.001 18.0 0.2 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KII93072.1 - 0.0067 15.5 0.2 0.0079 15.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KII93072.1 - 0.02 15.3 0.1 0.02 15.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII93072.1 - 0.036 13.8 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KII93072.1 - 0.042 12.9 0.0 0.047 12.7 0.0 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KII93072.1 - 0.09 11.6 0.2 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KII93072.1 - 0.13 11.9 0.1 0.17 11.5 0.1 1.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Adaptin_N PF01602.15 KII93074.1 - 4.2e-92 309.1 4.9 6.2e-92 308.6 3.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KII93074.1 - 3.7e-66 220.7 0.0 8.7e-66 219.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KII93074.1 - 2e-58 196.0 0.0 6.1e-58 194.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KII93074.1 - 7.3e-12 45.4 0.2 0.00042 20.5 0.0 4.6 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 KII93074.1 - 5.7e-08 32.2 0.3 0.082 13.0 0.0 5.5 4 1 1 5 5 5 1 HEAT repeat Cnd1 PF12717.2 KII93074.1 - 2.5e-05 24.2 4.7 0.42 10.4 0.0 4.8 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 KII93074.1 - 0.0083 16.0 0.5 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 Parkin co-regulated protein FtsK_SpoIIIE PF01580.13 KII93074.1 - 0.02 14.3 0.1 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT_EZ PF13513.1 KII93074.1 - 0.046 14.2 0.2 8.9 6.9 0.0 4.5 5 1 0 5 5 5 0 HEAT-like repeat Gemini_V1 PF01524.12 KII93074.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Geminivirus V1 protein Transp_cyt_pur PF02133.10 KII93075.1 - 6.9e-32 110.5 27.9 1e-31 109.9 19.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fasciclin PF02469.17 KII93078.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain DPM3 PF08285.6 KII93079.1 - 5.5e-31 106.2 0.2 6e-31 106.1 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ERG2_Sigma1R PF04622.7 KII93080.1 - 2.9e-84 281.6 0.3 3.5e-84 281.3 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein CSTF2_hinge PF14327.1 KII93081.1 - 1.8e-11 43.9 0.6 1.8e-11 43.9 0.4 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 KII93081.1 - 9.4e-07 28.0 1.5 2.7e-06 26.5 1.0 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Peptidase_M43 PF05572.8 KII93082.1 - 4.3e-20 71.8 0.7 8.4e-20 70.9 0.1 1.8 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KII93082.1 - 4e-06 26.8 1.8 5.8e-06 26.3 1.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KII93082.1 - 5e-05 23.4 2.7 9.9e-05 22.4 1.9 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KII93082.1 - 0.0005 20.6 1.4 0.0005 20.6 1.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KII93082.1 - 0.0006 19.3 1.2 0.0013 18.3 0.8 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KII93082.1 - 0.01 15.5 2.1 0.011 15.4 0.1 1.9 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 KII93082.1 - 0.021 14.5 0.2 0.035 13.8 0.1 1.3 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 KII93082.1 - 0.058 12.2 0.5 0.1 11.4 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.8 KII93083.1 - 2.8e-17 62.7 0.2 5.2e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KII93083.1 - 8.7e-06 25.7 0.1 1.3e-05 25.2 0.1 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KII93083.1 - 2.1e-05 24.6 0.1 3.4e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KII93083.1 - 0.00078 19.1 1.9 0.0015 18.2 0.9 1.7 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 KII93083.1 - 0.0077 15.7 0.7 0.0099 15.4 0.5 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KII93083.1 - 0.012 16.1 0.0 0.018 15.5 0.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KII93083.1 - 0.025 13.4 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 KII93083.1 - 0.059 12.6 5.4 0.56 9.5 3.8 2.1 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase F-box-like PF12937.2 KII93084.1 - 7e-09 35.2 0.9 2.4e-08 33.5 0.6 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KII93084.1 - 0.079 12.6 3.6 3.3 7.4 0.1 2.5 2 0 0 2 2 2 0 F-box domain ubiquitin PF00240.18 KII93085.1 - 1.7e-35 120.2 0.7 1.9e-35 120.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KII93085.1 - 1.4e-18 66.3 0.3 1.6e-18 66.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KII93085.1 - 2.7e-06 27.5 0.1 1.1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KII93085.1 - 0.0016 18.1 0.0 0.0018 17.9 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KII93085.1 - 0.0033 17.2 0.1 0.0071 16.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KII93085.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KII93085.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Tash_PEST PF07708.6 KII93085.1 - 0.33 10.9 1.8 0.64 10.0 1.2 1.4 1 0 0 1 1 1 0 Tash protein PEST motif Adap_comp_sub PF00928.16 KII93087.1 - 6.6e-23 81.1 0.0 1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KII93087.1 - 1.1e-07 31.6 0.1 1.8e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 KII93088.1 - 2.9e-68 229.7 0.0 3.3e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII93089.1 - 1.8e-65 220.5 0.0 2.3e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPX2 PF06886.6 KII93091.1 - 3.6e-10 39.7 20.1 5.5e-10 39.1 13.9 1.3 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) Endonuc_Holl PF10107.4 KII93091.1 - 0.13 11.9 2.3 0.18 11.5 1.6 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Oxysterol_BP PF01237.13 KII93091.1 - 1.1 7.6 3.5 1.3 7.4 2.4 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein DUF4207 PF13904.1 KII93091.1 - 6.8 5.9 11.8 7.9 5.7 8.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) ECH PF00378.15 KII93093.1 - 1.2e-46 158.8 0.2 1.5e-46 158.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_M76 PF09768.4 KII93094.1 - 6.6e-67 224.2 4.7 8.2e-67 223.9 3.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KII93094.1 - 0.56 9.8 6.8 0.26 10.9 2.2 2.0 1 1 1 2 2 2 0 SprT-like family DUF1705 PF08019.7 KII93095.1 - 0.13 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) GPI-anchored PF10342.4 KII93096.1 - 1.1e-11 45.0 0.5 1.1e-11 45.0 0.4 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DGF-1_4 PF11024.3 KII93098.1 - 0.044 14.1 1.3 0.081 13.3 0.9 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 CIMR PF00878.13 KII93099.1 - 5.8e-12 45.5 0.1 4.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KII93099.1 - 2.4e-06 26.9 0.2 2.6e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 KII93099.1 - 0.046 12.7 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Complex1_49kDa PF00346.14 KII93100.1 - 2.5e-126 420.2 0.0 3.1e-126 419.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KII93100.1 - 0.043 12.5 0.0 0.084 11.6 0.0 1.4 2 0 0 2 2 2 0 Nickel-dependent hydrogenase Fungal_trans PF04082.13 KII93101.1 - 1.9e-21 76.1 2.6 5.6e-21 74.5 1.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII93101.1 - 3.8e-05 23.5 13.7 8e-05 22.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Spc34 PF08657.5 KII93101.1 - 0.11 12.1 0.5 0.17 11.4 0.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF2339 PF10101.4 KII93101.1 - 0.24 9.6 1.0 0.35 9.0 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Utp14 PF04615.8 KII93102.1 - 2.5e-171 571.5 51.1 2.5e-171 571.5 35.4 2.2 1 1 1 2 2 2 1 Utp14 protein Tetraspannin PF00335.15 KII93103.1 - 4.7e-12 45.6 13.9 6e-12 45.3 9.6 1.1 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.9 KII93103.1 - 0.017 14.0 0.5 0.03 13.2 0.3 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family DUF106 PF01956.11 KII93103.1 - 0.047 13.2 2.3 1.3 8.5 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein DUF106 DIOX_N PF14226.1 KII93104.1 - 9.6e-16 58.3 0.0 1.6e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII93104.1 - 3.9e-11 43.0 0.0 6.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KII93105.1 - 2.5e-14 53.8 0.0 4e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII93105.1 - 2.9e-11 43.5 0.0 6.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rhodanese PF00581.15 KII93106.1 - 7.2e-06 26.3 0.0 8.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain EF-hand_6 PF13405.1 KII93107.1 - 0.012 15.3 0.3 0.065 13.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain YcfA PF07927.7 KII93107.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 YcfA-like protein PhaP_Bmeg PF09602.5 KII93108.1 - 0.002 17.9 4.2 0.0046 16.7 2.9 1.6 1 1 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF2854 PF11016.3 KII93108.1 - 0.012 15.1 4.4 0.16 11.4 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2854) MscS_porin PF12795.2 KII93108.1 - 0.022 14.1 9.4 0.029 13.7 6.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 KII93108.1 - 0.043 12.9 1.3 0.058 12.5 0.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 KII93108.1 - 0.083 12.4 6.7 0.12 11.9 4.6 1.1 1 0 0 1 1 1 0 IncA protein TraF_2 PF13729.1 KII93108.1 - 0.11 11.2 1.0 0.13 11.0 0.7 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF4337 PF14235.1 KII93108.1 - 0.12 12.1 7.9 0.26 11.1 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) CENP-H PF05837.7 KII93108.1 - 0.14 12.3 5.8 0.15 12.2 3.5 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.6 KII93108.1 - 0.15 10.6 8.8 0.18 10.4 6.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KII93108.1 - 0.29 10.9 3.7 4.5 7.0 1.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 KII93108.1 - 0.3 10.6 7.8 0.97 8.9 5.4 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3417 PF11897.3 KII93108.1 - 0.43 10.5 3.1 0.8 9.6 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) Prefoldin_2 PF01920.15 KII93108.1 - 0.46 10.2 6.4 0.24 11.1 0.3 2.4 2 1 0 2 2 2 0 Prefoldin subunit Tropomyosin_1 PF12718.2 KII93108.1 - 0.81 9.5 10.5 7.7 6.3 2.8 2.0 1 1 0 1 1 1 0 Tropomyosin like TPR_MLP1_2 PF07926.7 KII93108.1 - 1.2 8.9 9.8 1.6 8.4 1.7 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.1 KII93108.1 - 2.2 8.6 6.1 4 7.8 0.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DUF3192 PF11399.3 KII93108.1 - 2.2 8.2 5.1 4.9 7.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3192) MADF_DNA_bdg PF10545.4 KII93108.1 - 4.6 7.5 6.9 1.8 8.8 1.3 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ING PF12998.2 KII93108.1 - 5 7.4 8.3 42 4.4 5.7 2.0 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Atg14 PF10186.4 KII93108.1 - 6.1 5.6 13.2 32 3.3 9.1 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KII93108.1 - 7.7 6.9 8.1 3e+02 1.7 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Cohesin_load PF10345.4 KII93109.1 - 0.45 8.6 0.5 2.7 6.0 0.1 2.0 2 0 0 2 2 2 0 Cohesin loading factor PGAP1 PF07819.8 KII93110.1 - 1.3e-08 34.7 0.1 2.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KII93110.1 - 5.1e-05 23.2 0.7 5.1e-05 23.2 0.5 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII93110.1 - 0.00034 20.3 0.1 0.00068 19.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KII93110.1 - 0.00066 19.0 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KII93110.1 - 0.0015 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 KII93110.1 - 0.012 14.7 0.0 0.05 12.6 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 KII93110.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 KII93110.1 - 0.04 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 KII93110.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF3180 PF11377.3 KII93111.1 - 0.62 9.9 7.8 0.039 13.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Nse4_C PF08743.5 KII93112.1 - 1e-26 92.7 0.3 2.3e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KII93112.1 - 2.5e-13 49.6 1.0 7.1e-13 48.1 0.7 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE GDH_N PF12466.3 KII93113.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Metalloenzyme PF01676.13 KII93114.1 - 5.4e-77 258.5 0.5 6.2e-77 258.3 0.3 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KII93114.1 - 9.7e-71 237.6 0.0 1.6e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.18 KII93114.1 - 1e-06 28.1 0.3 3.1e-05 23.2 0.1 2.7 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KII93114.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 KII93114.1 - 0.0017 18.0 0.0 0.0071 16.0 0.0 1.9 2 0 0 2 2 2 1 PglZ domain Alk_phosphatase PF00245.15 KII93114.1 - 0.0024 16.6 0.2 0.041 12.5 0.2 2.2 2 0 0 2 2 2 1 Alkaline phosphatase MFS_1 PF07690.11 KII93115.1 - 4e-37 127.7 40.9 6.3e-37 127.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 KII93116.1 - 8e-07 28.6 0.8 4.7e-06 26.2 0.5 2.4 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII93116.1 - 9.6e-05 21.9 0.1 0.32 10.6 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KII93116.1 - 1.4 8.6 6.0 0.26 10.9 0.6 2.5 3 0 0 3 3 3 0 F-box domain Caveolin PF01146.12 KII93118.1 - 0.22 11.0 4.1 0.46 10.0 2.8 1.5 1 0 0 1 1 1 0 Caveolin Polysacc_deac_1 PF01522.16 KII93119.1 - 0.00051 19.6 0.5 0.0025 17.4 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide deacetylase tRNA-synt_His PF13393.1 KII93120.1 - 1.5e-42 145.7 0.7 4.4e-38 131.1 0.0 2.6 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KII93120.1 - 2.8e-18 66.0 0.0 4.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KII93120.1 - 4.4e-10 39.3 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.14 KII93120.1 - 0.015 15.6 0.7 0.015 15.6 0.5 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein NTS_2 PF15448.1 KII93120.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein DivIC PF04977.10 KII93120.1 - 0.11 11.9 0.7 0.26 10.7 0.5 1.6 1 0 0 1 1 1 0 Septum formation initiator tRNA-synt_2 PF00152.15 KII93120.1 - 0.17 10.6 0.0 3.9 6.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Ank_2 PF12796.2 KII93121.1 - 1.4e-17 63.7 0.1 9.4e-13 48.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII93121.1 - 1.4e-13 49.8 0.3 1.4e-05 24.5 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KII93121.1 - 1.5e-13 50.8 0.1 1.5e-07 31.7 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII93121.1 - 1.2e-12 47.5 0.1 3.4e-05 23.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII93121.1 - 2.3e-11 42.7 0.1 1.2e-05 25.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat SNF2_N PF00176.18 KII93122.1 - 5.8e-74 248.5 0.1 9.9e-74 247.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KII93122.1 - 9.9e-40 134.9 4.5 1.3e-39 134.5 0.5 3.0 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 KII93122.1 - 1.6e-28 99.3 0.5 1.6e-28 99.3 0.3 3.3 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KII93122.1 - 4e-14 52.2 0.0 1.2e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII93122.1 - 4.1e-08 33.2 0.0 3.2e-07 30.3 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KII93122.1 - 0.00071 19.1 0.4 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.1 KII93122.1 - 0.0028 17.6 4.5 0.0028 17.6 3.1 3.9 5 0 0 5 5 5 1 DNA-binding domain AAA_14 PF13173.1 KII93122.1 - 0.006 16.4 1.3 0.042 13.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain F-box-like PF12937.2 KII93123.1 - 4.3e-08 32.7 0.6 1.6e-07 30.9 0.4 2.0 1 1 0 1 1 1 1 F-box-like XPG_I PF00867.13 KII93125.1 - 4.1e-16 58.8 0.0 6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KII93125.1 - 3.3e-06 27.3 0.0 5.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain SMC_N PF02463.14 KII93128.1 - 1.7e-74 249.7 0.5 3.3e-74 248.8 0.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KII93128.1 - 1.1e-27 96.4 0.2 6.5e-27 93.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KII93128.1 - 6.5e-13 49.2 7.3 1.1e-05 25.5 1.3 3.1 3 1 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 KII93128.1 - 2.1e-07 30.4 25.6 0.0001 21.6 1.3 3.8 3 1 1 4 4 4 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 KII93128.1 - 1.9e-06 27.3 0.0 3.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NPR2 PF06218.6 KII93128.1 - 0.021 13.5 1.7 0.054 12.1 1.2 1.6 1 0 0 1 1 1 0 Nitrogen permease regulator 2 ABC_tran PF00005.22 KII93128.1 - 0.8 10.0 0.0 0.8 10.0 0.0 5.5 4 3 0 4 4 4 0 ABC transporter Pkinase PF00069.20 KII93129.1 - 2.7e-39 134.9 0.0 1.6e-34 119.2 0.0 2.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93129.1 - 5e-20 71.6 0.0 9.2e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93129.1 - 3.3e-06 26.2 0.0 7.1e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII93129.1 - 1.4e-05 24.9 0.9 0.0016 18.1 0.0 3.0 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KII93129.1 - 0.00023 20.3 0.1 0.00039 19.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KII93129.1 - 0.0093 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 KII93129.1 - 0.056 13.0 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.2 KII93130.1 - 0.0013 18.4 0.5 0.0047 16.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like DUF2235 PF09994.4 KII93131.1 - 1.3e-64 218.2 0.3 1.6e-64 217.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KII93131.1 - 0.058 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 KII93131.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DEAD PF00270.24 KII93132.1 - 0.0066 15.9 0.0 0.0088 15.5 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase TIR_2 PF13676.1 KII93132.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 TIR domain Fungal_trans PF04082.13 KII93133.1 - 4.4e-20 71.6 2.3 4.4e-20 71.6 1.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII93133.1 - 0.00076 19.3 14.8 0.0015 18.4 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain H-kinase_dim PF02895.9 KII93133.1 - 0.073 13.4 0.3 9.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain HMGL-like PF00682.14 KII93134.1 - 1.1e-42 146.3 0.0 1.8e-42 145.6 0.0 1.4 1 1 0 1 1 1 1 HMGL-like CDP-OH_P_transf PF01066.16 KII93135.1 - 1e-16 61.0 0.4 1e-16 61.0 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase F-box-like PF12937.2 KII93136.1 - 0.0013 18.4 0.3 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 F-box-like tRNA_bind_2 PF13725.1 KII93136.1 - 0.092 12.8 0.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Possible tRNA binding domain SDA1 PF05285.7 KII93137.1 - 4.7 6.3 8.7 6.1 6.0 6.0 1.1 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.2 KII93138.1 - 4.6e-07 29.4 3.8 1.4e-06 27.9 0.8 2.7 2 1 0 2 2 2 1 F-box-like Homeobox PF00046.24 KII93140.1 - 1.7e-15 56.3 2.2 3.3e-15 55.4 1.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KII93140.1 - 0.0065 16.1 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain F-box-like PF12937.2 KII93141.1 - 7.2e-05 22.4 0.1 0.00013 21.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII93142.1 - 2.1e-07 30.5 0.1 7.2e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 F-box-like FliD_C PF07195.7 KII93142.1 - 0.0072 15.6 1.3 0.011 15.0 0.9 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Allexi_40kDa PF05549.6 KII93142.1 - 0.017 14.4 2.7 0.93 8.7 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Elongin_A PF06881.6 KII93142.1 - 0.021 15.2 0.1 0.065 13.6 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Tropomyosin_1 PF12718.2 KII93142.1 - 0.053 13.3 4.7 0.12 12.2 3.3 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF2935 PF11155.3 KII93142.1 - 0.073 13.1 0.8 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) KfrA_N PF11740.3 KII93142.1 - 0.16 12.3 5.2 0.29 11.5 3.6 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term OmpH PF03938.9 KII93142.1 - 0.44 10.4 4.8 0.69 9.8 3.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CCDC155 PF14662.1 KII93142.1 - 1.1 8.8 10.8 1.8 8.1 7.5 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF904 PF06005.7 KII93142.1 - 2.9 8.2 11.0 1.2 9.5 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 KII93142.1 - 3.5 7.6 8.0 2.2 8.3 1.3 2.3 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.10 KII93142.1 - 5.4 6.5 7.2 2.8 7.5 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator LTXXQ PF07813.7 KII93144.1 - 0.55 10.7 7.2 1.3 9.5 5.0 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein PAPA-1 PF04795.7 KII93144.1 - 9 7.0 9.1 4.6 8.0 3.6 2.4 2 0 0 2 2 2 0 PAPA-1-like conserved region Pyridox_oxidase PF01243.15 KII93145.1 - 4.4e-08 33.0 0.0 1.5e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Laminin_II PF06009.7 KII93146.1 - 0.015 15.0 8.5 0.024 14.3 5.9 1.3 1 0 0 1 1 1 0 Laminin Domain II Myosin_tail_1 PF01576.14 KII93146.1 - 0.054 11.2 4.1 0.07 10.8 2.8 1.0 1 0 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 KII93146.1 - 0.44 9.6 9.0 0.61 9.2 6.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DEADboxA PF12343.3 KII93146.1 - 2.1 8.6 9.5 0.25 11.6 2.3 2.4 2 0 0 2 2 2 0 Cold shock protein DEAD box A Fib_alpha PF08702.5 KII93146.1 - 5.3 7.1 7.6 0.79 9.8 2.7 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 KII93146.1 - 6.2 7.1 17.6 0.53 10.5 6.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CBM_21 PF03370.8 KII93147.1 - 1.8e-14 53.6 0.0 2.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Putative phosphatase regulatory subunit F-box-like PF12937.2 KII93150.1 - 7.8e-08 31.9 0.1 3.5e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 F-box-like Homeobox PF00046.24 KII93151.1 - 7.4e-14 51.1 1.3 1.1e-13 50.5 0.9 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KII93151.1 - 0.00015 21.3 0.2 0.00032 20.3 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain adh_short PF00106.20 KII93152.1 - 1.2e-19 70.8 1.0 2.2e-19 70.0 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII93152.1 - 2.5e-09 37.2 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII93152.1 - 1.2e-08 34.8 0.1 1.7e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_16 PF10294.4 KII93153.1 - 1.2e-17 63.8 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII93153.1 - 2.1e-09 37.9 0.0 4.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII93153.1 - 7.2e-09 35.1 0.1 1e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KII93153.1 - 4.9e-06 26.5 0.5 1e-05 25.5 0.4 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII93153.1 - 1.9e-05 24.0 0.1 3.1e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KII93153.1 - 0.00025 21.4 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII93153.1 - 0.0034 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KII93153.1 - 0.0038 16.6 0.1 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KII93153.1 - 0.004 17.5 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII93153.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KII93153.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Gon7 PF08738.5 KII93154.1 - 0.0042 17.0 0.1 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 Gon7 family Cpn60_TCP1 PF00118.19 KII93155.1 - 3.4e-153 510.7 1.0 3.9e-153 510.5 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.20 KII93156.1 - 1.8e-25 89.7 1.2 2.6e-25 89.2 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII93156.1 - 9.4e-16 58.2 0.0 1.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII93156.1 - 1.9e-09 37.4 1.2 2.8e-09 36.8 0.9 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII93156.1 - 0.00014 21.9 0.2 0.00023 21.2 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KII93156.1 - 0.00039 19.6 0.0 0.00053 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KII93156.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 KII93156.1 - 0.061 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KII93158.1 - 1.5e-12 47.8 0.3 2.3e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII93158.1 - 2e-09 37.6 2.2 2.6e-07 30.9 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII93158.1 - 0.0014 18.4 0.1 0.22 11.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KII93158.1 - 0.048 12.5 8.1 0.38 9.6 0.1 3.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase DUF3530 PF12048.3 KII93158.1 - 0.095 11.6 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Lycopene_cycl PF05834.7 KII93158.1 - 0.12 11.3 0.1 4.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_11 PF08241.7 KII93159.1 - 1.3e-12 47.9 0.0 2.9e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII93159.1 - 2.9e-09 36.8 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII93159.1 - 3.7e-09 36.8 0.0 7.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII93159.1 - 6e-09 35.3 0.0 1.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KII93159.1 - 7.8e-09 36.1 0.0 2.5e-08 34.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII93159.1 - 7.3e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII93159.1 - 4.5e-05 23.4 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII93159.1 - 0.00011 21.3 0.0 0.00028 20.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 KII93159.1 - 0.00013 21.5 0.0 0.00042 19.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KII93159.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KII93159.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 KII93159.1 - 0.0058 15.0 0.0 0.012 13.9 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 KII93159.1 - 0.072 12.7 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.14 KII93159.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RAP1 PF07218.6 KII93159.1 - 0.23 9.5 3.7 0.32 9.0 2.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF605 PF04652.11 KII93162.1 - 1e-69 235.8 36.4 8.8e-52 176.7 12.1 2.8 1 1 1 2 2 2 2 Vta1 like UVR PF02151.14 KII93162.1 - 0.45 10.0 1.9 0.85 9.2 1.3 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif Nop52 PF05997.7 KII93163.1 - 2e-67 226.7 0.0 3e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 KII93163.1 - 3.1e-06 26.6 0.0 7.1e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Transthyretin PF00576.16 KII93164.1 - 1e-30 105.8 0.3 3.1e-30 104.3 0.2 1.7 1 1 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 KII93164.1 - 0.016 15.7 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain DUF1122 PF06557.6 KII93164.1 - 0.081 12.0 0.0 7.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1122) UQ_con PF00179.21 KII93165.1 - 4.5e-38 129.8 0.0 5.8e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KII93165.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain adh_short_C2 PF13561.1 KII93166.1 - 1.8e-21 77.0 0.0 2.1e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII93166.1 - 6.5e-20 71.7 0.1 8.4e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII93166.1 - 1.4e-08 34.6 0.1 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KII93166.1 - 2.2e-05 23.7 0.1 2.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KII93166.1 - 0.063 12.3 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KII93166.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cyt-b5 PF00173.23 KII93167.1 - 3.8e-10 39.4 0.0 5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIOX_N PF14226.1 KII93168.1 - 0.00061 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII93168.1 - 0.0022 18.2 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rossmann-like PF10727.4 KII93168.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain F-box-like PF12937.2 KII93169.1 - 0.0018 17.9 1.4 0.0034 17.0 0.0 2.3 3 0 0 3 3 3 1 F-box-like MMR_HSR1 PF01926.18 KII93170.1 - 1.2e-13 51.0 0.0 2.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII93170.1 - 4.5e-06 26.0 0.0 1.2e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KII93170.1 - 0.00094 18.3 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KII93170.1 - 0.017 15.6 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KII93170.1 - 0.039 13.7 0.1 0.039 13.7 0.1 2.3 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.11 KII93170.1 - 0.16 11.0 0.0 0.34 10.0 0.0 1.4 2 0 0 2 2 2 0 AIG1 family RNA_pol_Rpc4 PF05132.9 KII93170.1 - 0.23 11.4 2.7 0.56 10.1 1.3 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pyr_redox_2 PF07992.9 KII93171.1 - 2.6e-13 50.3 0.4 3.7e-13 49.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KII93171.1 - 1.3e-10 41.4 0.4 5.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII93171.1 - 1.6e-05 23.9 4.5 0.022 13.6 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII93171.1 - 7.7e-05 22.8 0.0 0.067 13.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII93171.1 - 0.00012 21.1 0.8 0.46 9.3 0.0 2.9 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KII93171.1 - 0.0009 19.0 0.0 0.11 12.2 0.1 2.8 3 0 0 3 3 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KII93171.1 - 0.0015 17.4 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF4147 PF13660.1 KII93171.1 - 0.0025 16.9 0.1 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4147) TrkA_N PF02254.13 KII93171.1 - 0.003 17.5 0.8 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_7 PF13241.1 KII93171.1 - 0.014 15.6 0.1 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 KII93171.1 - 0.019 13.5 1.8 0.085 11.4 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase DUF3530 PF12048.3 KII93171.1 - 0.03 13.2 0.1 0.093 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Malic_M PF03949.10 KII93171.1 - 0.035 13.6 0.5 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 KII93171.1 - 0.067 12.7 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.8 KII93171.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII93171.1 - 0.11 12.3 1.8 3.1 7.5 0.1 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family GIDA PF01134.17 KII93171.1 - 3.6 6.3 7.6 11 4.6 0.0 3.1 3 1 0 3 3 3 0 Glucose inhibited division protein A WD40 PF00400.27 KII93174.1 - 4.9e-22 76.9 4.3 4.3e-05 23.2 0.1 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat PD40 PF07676.7 KII93174.1 - 0.019 14.5 0.3 3.1 7.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Homeobox PF00046.24 KII93175.1 - 1.5e-16 59.7 0.8 2.8e-16 58.8 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Arrestin_C PF02752.17 KII93176.1 - 4.3e-05 23.6 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain RabGAP-TBC PF00566.13 KII93180.1 - 1.3e-29 103.2 0.0 2e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spc97_Spc98 PF04130.8 KII93181.1 - 1.3e-71 241.5 0.0 1.9e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Ribosomal_S28e PF01200.13 KII93183.1 - 4.7e-34 115.9 1.7 5.2e-34 115.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.15 KII93184.1 - 5.2e-27 94.7 0.0 1e-26 93.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KII93184.1 - 4e-06 26.3 0.0 5.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Peptidase_M22 PF00814.20 KII93185.1 - 1.2e-83 280.6 0.0 1.4e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Glyco_hydro_28 PF00295.12 KII93186.1 - 8.8e-38 130.0 3.8 1.2e-37 129.5 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_65m PF03632.10 KII93188.1 - 0.032 12.9 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Eno-Rase_FAD_bd PF07055.7 KII93190.1 - 0.048 13.6 3.2 0.3 11.0 1.2 2.5 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Aminotran_1_2 PF00155.16 KII93192.1 - 5.6e-90 301.8 0.0 6.5e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Phage_1_1 PF08200.6 KII93193.1 - 0.073 13.2 2.8 0.4 10.9 2.0 2.4 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein Tet_JBP PF12851.2 KII93194.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Ribosomal_L31e PF01198.14 KII93196.1 - 0.051 13.2 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L31e Cyclin_N PF00134.18 KII93198.1 - 6.4e-13 48.3 0.1 9.4e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KII93198.1 - 0.00014 21.6 0.0 0.0038 16.9 0.0 2.9 3 0 0 3 3 3 1 Transcription factor TFIIB repeat PsbP PF01789.11 KII93199.1 - 0.098 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PsbP AAA_18 PF13238.1 KII93200.1 - 8.7e-28 97.2 0.0 1.3e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII93200.1 - 2e-13 51.2 0.0 2.8e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII93200.1 - 0.00015 21.6 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KII93200.1 - 0.00096 19.3 0.0 0.0018 18.4 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KII93200.1 - 0.0013 17.9 0.4 0.59 9.1 0.0 2.3 2 1 0 2 2 2 2 KaiC AAA_28 PF13521.1 KII93200.1 - 0.0016 18.4 0.0 0.0036 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KII93200.1 - 0.0021 18.1 0.0 0.0042 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KII93200.1 - 0.0025 17.2 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.1 KII93200.1 - 0.0035 17.0 0.5 0.0067 16.1 0.4 1.4 1 0 0 1 1 1 1 Part of AAA domain ADK PF00406.17 KII93200.1 - 0.0041 17.0 0.0 0.088 12.6 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 KII93200.1 - 0.0062 15.7 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 KII93200.1 - 0.012 14.4 0.8 0.08 11.7 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 KII93200.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 KII93200.1 - 0.016 14.9 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 NTPase SKI PF01202.17 KII93200.1 - 0.027 14.3 0.1 0.063 13.1 0.1 1.6 1 1 0 1 1 1 0 Shikimate kinase AAA_14 PF13173.1 KII93200.1 - 0.028 14.3 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KII93200.1 - 0.058 12.8 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KII93200.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KII93200.1 - 0.074 12.4 0.0 0.15 11.5 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 KII93200.1 - 0.084 11.8 0.9 0.15 11.0 0.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 KII93200.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.1 KII93200.1 - 0.1 12.1 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 KII93200.1 - 0.1 11.9 0.1 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase IncA PF04156.9 KII93201.1 - 0.0037 16.8 0.9 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 IncA protein DUF3165 PF11364.3 KII93201.1 - 0.047 13.8 1.4 0.18 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Pro_Al_protease PF02983.9 KII93201.1 - 0.19 11.7 2.0 25 4.9 1.1 2.7 2 0 0 2 2 2 0 Alpha-lytic protease prodomain DUF4231 PF14015.1 KII93201.1 - 0.72 9.8 6.2 2.4 8.1 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF805 PF05656.9 KII93201.1 - 3.1 7.6 10.9 4 7.2 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Spt5-NGN PF03439.8 KII93202.1 - 8e-23 79.9 0.0 1.9e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 KII93202.1 - 4.9e-15 56.0 54.4 1.4e-08 35.2 16.3 3.4 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 KII93202.1 - 5.3e-14 51.2 20.7 1.9e-05 24.1 0.0 6.8 7 0 0 7 7 7 3 KOW motif Spt5_N PF11942.3 KII93202.1 - 4.4e-11 43.2 13.7 4.4e-11 43.2 9.5 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal YajC PF02699.10 KII93202.1 - 0.1 12.2 0.8 0.36 10.5 0.2 2.3 1 1 1 2 2 2 0 Preprotein translocase subunit O-FucT PF10250.4 KII93203.1 - 1.2e-08 34.5 0.0 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.2 KII93204.1 - 4.5e-07 29.4 0.3 1.9e-06 27.4 0.2 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII93204.1 - 0.098 12.3 0.6 11 5.7 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.1 KII93204.1 - 0.12 12.1 2.3 0.5 10.1 1.0 2.5 2 1 0 2 2 2 0 F-box-like domain Radical_SAM PF04055.16 KII93206.1 - 7.1e-14 52.3 0.0 1.4e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily JAB PF01398.16 KII93207.1 - 3.7e-13 49.1 0.0 6.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DPBB_1 PF03330.13 KII93208.1 - 1.1e-09 38.1 0.2 1.3e-09 37.9 0.1 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII93208.1 - 0.059 13.0 0.1 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Barwin family Cerato-platanin PF07249.7 KII93208.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Cerato-platanin Ipi1_N PF12333.3 KII93209.1 - 1.4e-14 53.8 0.0 2.2e-12 46.8 0.0 3.5 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 KII93209.1 - 0.013 15.4 0.0 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KII93209.1 - 0.053 13.8 0.8 0.43 10.9 0.0 3.0 4 0 0 4 4 4 0 HEAT repeats GRIP PF01465.15 KII93210.1 - 2.3e-17 62.2 0.8 5.8e-17 60.9 0.5 1.8 1 0 0 1 1 1 1 GRIP domain Filament PF00038.16 KII93210.1 - 0.22 10.9 71.3 0.23 10.8 10.0 3.8 1 1 3 4 4 4 0 Intermediate filament protein Arrestin_C PF02752.17 KII93211.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KII93211.1 - 0.021 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DDDD PF10161.4 KII93211.1 - 0.091 12.4 0.4 0.49 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Ras PF00071.17 KII93212.1 - 3.1e-55 185.9 0.0 3.8e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII93212.1 - 1.7e-17 64.0 0.0 2.5e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII93212.1 - 2.4e-14 52.9 0.0 1e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII93212.1 - 6.3e-08 32.0 0.0 7.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KII93212.1 - 6.2e-06 25.7 0.0 9.9e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII93212.1 - 0.00012 22.0 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase MRI PF15325.1 KII93212.1 - 0.028 15.3 1.3 0.046 14.6 0.9 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection AAA_16 PF13191.1 KII93212.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_6 PF12697.2 KII93213.1 - 1.7e-28 100.0 0.3 3e-28 99.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII93213.1 - 3.3e-11 43.1 0.0 5.7e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KII93213.1 - 1.5e-08 34.3 0.0 5.3e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KII93213.1 - 3.7e-08 33.2 0.8 6.4e-08 32.4 0.2 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KII93213.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.6 KII93213.1 - 0.0073 15.1 0.0 0.0096 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KII93213.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.7 KII93213.1 - 0.035 12.6 0.0 0.051 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 KII93214.1 - 7.9e-28 97.8 0.0 1.4e-27 97.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII93214.1 - 7.3e-11 42.0 0.0 1.4e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII93214.1 - 2.8e-09 36.8 0.6 4.5e-09 36.2 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KII93214.1 - 3.4e-06 26.8 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 KII93214.1 - 0.0049 16.1 0.0 0.0099 15.1 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase PF07224.6 KII93214.1 - 0.05 12.3 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AXE1 PF05448.7 KII93214.1 - 0.052 12.0 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 KII93214.1 - 0.054 12.3 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme tRNA-synt_2 PF00152.15 KII93215.1 - 2e-74 250.3 0.1 2.7e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KII93215.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KII93215.1 - 0.022 13.9 0.3 0.64 9.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Abhydrolase_6 PF12697.2 KII93216.1 - 1.8e-26 93.4 0.0 3.1e-26 92.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII93216.1 - 1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII93216.1 - 2e-09 37.3 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KII93216.1 - 3.6e-07 29.9 0.0 6.3e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase AXE1 PF05448.7 KII93216.1 - 0.011 14.2 0.0 0.076 11.4 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 KII93216.1 - 0.064 12.5 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase PF07224.6 KII93216.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Pil1 PF13805.1 KII93217.1 - 1.3e-22 80.2 1.0 2e-22 79.6 0.7 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 HDV_ag PF01517.13 KII93217.1 - 8.2 6.0 18.8 0.17 11.5 5.7 2.4 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen IF4E PF01652.13 KII93218.1 - 1.5e-46 157.9 0.0 2e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CBS PF00571.23 KII93219.1 - 5.2e-30 102.9 2.3 5.3e-12 45.3 0.0 4.4 4 0 0 4 4 4 4 CBS domain DEAD PF00270.24 KII93221.1 - 5.1e-17 61.8 0.0 7.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII93221.1 - 4.3e-06 26.6 0.0 6.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KII93221.1 - 0.00055 18.8 0.0 0.0007 18.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.1 KII93221.1 - 0.0066 16.0 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain SPRY PF00622.23 KII93223.1 - 7e-17 61.6 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Mucin PF01456.12 KII93224.1 - 0.017 14.9 0.2 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SMN PF06003.7 KII93228.1 - 1.5e-07 30.7 11.1 7.2e-07 28.5 7.7 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KII93228.1 - 0.00014 21.6 0.0 0.00043 20.1 0.0 1.8 2 1 0 2 2 2 1 Tudor domain DUF947 PF06102.7 KII93228.1 - 0.001 18.8 5.4 0.001 18.8 3.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Relaxase PF03432.9 KII93228.1 - 0.0049 16.2 1.8 0.0079 15.6 1.2 1.3 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain PWWP PF00855.12 KII93228.1 - 0.0094 16.1 3.3 0.086 13.0 2.3 2.3 1 1 0 1 1 1 1 PWWP domain PDCD2_C PF04194.8 KII93228.1 - 0.22 11.0 3.9 0.45 10.0 2.7 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Ycf1 PF05758.7 KII93228.1 - 0.53 7.9 5.6 0.72 7.4 3.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF1387 PF07139.6 KII93228.1 - 8.3 5.9 15.8 0.9 9.0 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF1764 PF08576.5 KII93229.1 - 1.1e-08 35.7 9.9 4.3e-07 30.6 1.2 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Ribosomal_60s PF00428.14 KII93229.1 - 0.013 15.8 12.8 0.068 13.5 1.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NST1 PF13945.1 KII93229.1 - 0.53 10.3 5.8 0.68 9.9 4.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Mitofilin PF09731.4 KII93229.1 - 1.1 7.7 6.3 1.2 7.7 4.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ARID PF01388.16 KII93230.1 - 4.1e-09 36.1 0.0 9.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3518 PF12031.3 KII93230.1 - 0.00012 21.0 0.3 0.0074 15.1 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3518) Cation_efflux PF01545.16 KII93231.1 - 4.2e-78 262.2 4.7 5.9e-78 261.8 3.3 1.2 1 0 0 1 1 1 1 Cation efflux family Med5 PF08689.5 KII93232.1 - 3.4e-24 84.6 0.4 4e-23 81.1 0.1 2.0 1 1 0 1 1 1 1 Mediator complex subunit Med5 Abhydrolase_6 PF12697.2 KII93233.1 - 1.8e-23 83.5 0.0 2.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII93233.1 - 3.2e-08 33.4 0.0 6.8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII93233.1 - 3.5e-07 30.0 0.0 9.5e-07 28.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KII93233.1 - 5.5e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KII93233.1 - 0.0067 15.7 0.0 0.092 12.0 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 KII93233.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Sin_N PF04801.8 KII93234.1 - 5.3e-19 68.3 0.0 6.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Mpv17_PMP22 PF04117.7 KII93238.1 - 0.013 15.1 0.1 0.013 15.1 0.1 2.1 2 0 0 2 2 2 0 Mpv17 / PMP22 family LIM PF00412.17 KII93239.1 - 1.6e-14 53.7 13.0 2.2e-06 27.6 1.3 5.0 5 0 0 5 5 5 3 LIM domain zf-PARP PF00645.13 KII93239.1 - 0.14 12.4 0.4 0.7 10.1 0.0 2.3 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DnaJ PF00226.26 KII93241.1 - 1.6e-19 69.4 0.5 2.7e-19 68.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 KII93241.1 - 0.021 14.8 1.7 0.035 14.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 KII93241.1 - 0.039 13.5 8.2 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain nlz1 PF12402.3 KII93241.1 - 0.084 13.2 0.1 0.084 13.2 0.1 3.0 4 1 0 4 4 4 0 NocA-like zinc-finger protein 1 Gly-zipper_YMGG PF13441.1 KII93241.1 - 0.087 12.3 20.2 0.47 10.0 2.1 2.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 KII93241.1 - 1.1 9.4 14.6 3.5 7.8 4.5 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 KII93241.1 - 2.7 7.6 23.0 2.4 7.8 3.0 2.6 2 1 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 KII93241.1 - 2.8 7.6 22.5 3 7.5 2.9 3.3 2 1 1 3 3 3 0 Glycine zipper 2TM domain F-box-like PF12937.2 KII93242.1 - 6.4e-08 32.2 0.5 2e-07 30.6 0.4 1.9 1 0 0 1 1 1 1 F-box-like Myb_DNA-bind_2 PF08914.6 KII93243.1 - 3.1e-09 36.4 3.4 3.6e-09 36.2 1.2 2.0 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KII93243.1 - 0.061 13.8 3.2 0.51 10.9 2.2 2.4 2 1 0 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.20 KII93244.1 - 5e-69 232.3 0.0 6e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93244.1 - 8.5e-27 93.8 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93244.1 - 2.5e-06 26.7 0.1 5.6e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KII93244.1 - 0.0065 15.8 0.0 0.014 14.7 0.0 1.5 2 0 0 2 2 2 1 RIO1 family DnaJ PF00226.26 KII93245.1 - 1.2e-13 50.5 0.2 1.7e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KII93245.1 - 4.7e-13 48.4 0.7 6.2e-13 48.0 0.5 1.2 1 0 0 1 1 1 1 CSL zinc finger Bclt PF15318.1 KII93245.1 - 0.0014 18.6 0.0 0.0016 18.4 0.0 1.0 1 0 0 1 1 1 1 Putative Bcl-2 like protein of testis IBR PF01485.16 KII93246.1 - 0.11 12.4 1.0 0.2 11.5 0.7 1.4 1 0 0 1 1 1 0 IBR domain Cmc1 PF08583.5 KII93247.1 - 5.9e-12 45.1 0.8 7.1e-12 44.9 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like PEX11 PF05648.9 KII93248.1 - 1e-49 168.8 0.4 1.2e-49 168.6 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Anth_synt_I_N PF04715.8 KII93248.1 - 0.043 13.8 0.1 0.36 10.8 0.0 2.2 1 1 1 2 2 2 0 Anthranilate synthase component I, N terminal region Lyase_1 PF00206.15 KII93250.1 - 3.3e-120 400.9 0.0 4.3e-120 400.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KII93250.1 - 1.7e-20 72.8 0.0 3.7e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus G-alpha PF00503.15 KII93250.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SNF2_N PF00176.18 KII93253.1 - 6.8e-68 228.6 2.3 1.4e-67 227.6 1.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KII93253.1 - 1.1e-47 161.5 23.0 1.1e-47 161.5 15.9 2.4 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 KII93253.1 - 2.8e-13 49.5 0.0 8e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KII93253.1 - 4.4e-07 29.0 0.0 1.1e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KII93253.1 - 2.7e-06 27.3 0.2 1.1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HA2 PF04408.18 KII93254.1 - 9.3e-19 67.3 0.0 2.6e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KII93254.1 - 1.7e-12 47.0 0.1 4.3e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KII93254.1 - 4.6e-11 42.5 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KII93254.1 - 2.5e-07 30.9 0.1 7.5e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KII93254.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KII93254.1 - 0.017 15.1 0.1 0.1 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KII93254.1 - 0.021 15.1 0.0 0.078 13.2 0.0 2.0 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.17 KII93254.1 - 0.029 13.2 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SPX PF03105.14 KII93254.1 - 0.039 13.7 3.6 0.034 13.9 1.0 1.9 1 1 1 2 2 2 0 SPX domain T2SE PF00437.15 KII93254.1 - 0.04 12.8 0.0 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KII93254.1 - 0.089 12.3 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KII93254.1 - 0.2 10.8 0.0 0.42 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_L22e PF01776.12 KII93255.1 - 6.7e-46 154.9 0.1 8.4e-46 154.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DKCLD PF08068.7 KII93256.1 - 1.4e-30 104.9 0.1 4.8e-30 103.2 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KII93256.1 - 3.4e-24 85.6 0.4 1e-20 74.3 0.3 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KII93256.1 - 3.7e-21 74.6 1.4 8.3e-21 73.5 0.9 1.6 1 0 0 1 1 1 1 PUA domain Copper-bind PF00127.15 KII93257.1 - 2.9e-05 24.2 0.5 0.031 14.4 0.1 2.4 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 KII93257.1 - 0.0012 18.7 0.1 0.44 10.4 0.0 2.6 2 1 0 2 2 2 2 Cupredoxin-like domain Cu_bind_like PF02298.12 KII93257.1 - 0.026 14.3 0.3 4.6 7.1 0.2 2.8 2 1 0 2 2 2 0 Plastocyanin-like domain DUF3108 PF11306.3 KII93257.1 - 0.049 13.2 1.9 0.084 12.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Form-deh_trans PF09163.6 KII93257.1 - 0.12 11.8 0.2 0.12 11.8 0.2 2.6 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Pkinase PF00069.20 KII93258.1 - 4.5e-66 222.6 0.0 5.4e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93258.1 - 1.8e-27 96.0 0.0 3.4e-27 95.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93258.1 - 1.4e-06 27.5 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KII93258.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII93258.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.14 KII93258.1 - 0.053 12.8 0.4 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain RIO1 PF01163.17 KII93258.1 - 0.062 12.6 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Phage_GP20 PF06810.6 KII93259.1 - 0.0034 16.8 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 GAS PF13851.1 KII93259.1 - 0.014 14.6 0.6 0.025 13.7 0.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 KII93259.1 - 0.021 14.5 2.1 5.6 6.7 0.2 2.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 KII93259.1 - 0.04 13.8 5.1 3.4 7.6 0.3 3.5 2 1 2 4 4 4 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 KII93259.1 - 0.051 13.5 1.2 0.16 12.0 0.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 KII93259.1 - 0.064 12.9 3.9 0.19 11.4 2.6 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 KII93259.1 - 0.069 11.7 1.0 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.8 KII93259.1 - 0.074 12.7 2.1 0.67 9.7 1.5 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin PF02996.12 KII93259.1 - 0.1 12.2 1.1 0.48 10.0 0.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.4 KII93259.1 - 0.11 12.6 0.8 0.28 11.3 0.5 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 KII93259.1 - 0.16 12.3 1.6 0.43 10.9 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 KII93259.1 - 0.19 11.3 1.8 0.4 10.2 1.3 1.5 1 0 0 1 1 1 0 IncA protein DUF812 PF05667.6 KII93259.1 - 0.19 10.2 4.4 0.34 9.3 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ORF6C PF10552.4 KII93259.1 - 0.23 11.1 0.4 0.47 10.1 0.3 1.5 1 0 0 1 1 1 0 ORF6C domain DUF1192 PF06698.6 KII93259.1 - 0.33 10.7 3.3 18 5.2 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) DASH_Dad2 PF08654.5 KII93259.1 - 2.9 7.9 5.9 9.9 6.2 0.2 3.2 2 1 1 3 3 3 0 DASH complex subunit Dad2 FMN_dh PF01070.13 KII93260.1 - 9e-111 370.1 0.1 1.1e-110 369.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KII93260.1 - 1.3e-22 79.3 0.0 2.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KII93260.1 - 0.00041 19.3 0.0 0.00069 18.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KII93260.1 - 0.0013 17.6 0.3 0.0047 15.8 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KII93260.1 - 0.0054 15.9 0.1 0.014 14.5 0.1 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KII93260.1 - 0.063 12.3 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG SMP PF04927.7 KII93260.1 - 0.16 11.9 2.0 0.29 11.1 0.3 2.3 2 0 0 2 2 2 0 Seed maturation protein FAD-oxidase_C PF02913.14 KII93262.1 - 1.4e-50 171.9 0.0 1.8e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KII93262.1 - 5.8e-36 123.0 0.6 9.5e-36 122.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain GYF PF02213.11 KII93263.1 - 8.7e-13 47.6 0.0 1.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 GYF domain AMP-binding PF00501.23 KII93264.1 - 2.8e-73 246.7 0.2 3.3e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII93264.1 - 6.8e-19 68.5 0.1 1.9e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Alginate_lyase PF05426.7 KII93265.1 - 5.9e-49 166.8 6.4 4.7e-48 163.9 0.4 2.4 3 0 0 3 3 3 2 Alginate lyase CPSase_L_D2 PF02786.12 KII93266.1 - 5.2e-73 244.8 0.0 8.9e-73 244.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KII93266.1 - 1.2e-43 147.7 0.2 3.1e-43 146.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KII93266.1 - 7.7e-31 106.2 0.0 2.6e-30 104.5 0.0 1.9 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KII93266.1 - 1.5e-15 56.5 4.7 3e-15 55.5 3.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KII93266.1 - 1.2e-14 53.8 0.0 1.6e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KII93266.1 - 2.6e-13 50.1 0.0 3.6e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KII93266.1 - 3.8e-09 36.2 0.0 8.3e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KII93266.1 - 1.8e-07 30.7 0.0 4.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KII93266.1 - 0.00019 21.0 1.3 0.00099 18.7 0.5 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 KII93266.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KII93266.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain Toxin_59 PF15537.1 KII93266.1 - 0.035 14.1 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 59 NQRA PF05896.6 KII93266.1 - 0.071 12.2 0.7 0.12 11.4 0.5 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KII93266.1 - 0.16 11.0 0.8 0.3 10.1 0.3 1.5 1 1 1 2 2 2 0 HlyD family secretion protein HlyD PF00529.15 KII93266.1 - 0.38 10.0 3.3 1.1 8.4 1.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Vps51 PF08700.6 KII93267.1 - 2.9e-18 65.4 1.4 7.4e-18 64.1 1.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KII93267.1 - 5.9e-07 29.4 0.5 1.6e-06 28.0 0.3 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_S PF02609.11 KII93267.1 - 0.16 11.7 0.8 5 6.9 0.0 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Sel1 PF08238.7 KII93268.1 - 1.8e-43 146.0 22.0 2.2e-08 34.4 0.2 8.1 8 0 0 8 8 8 7 Sel1 repeat Med7 PF05983.6 KII93268.1 - 0.21 11.3 1.3 0.33 10.7 0.9 1.3 1 0 0 1 1 1 0 MED7 protein DNA_methylase PF00145.12 KII93270.1 - 1.1e-39 136.5 0.0 3.2e-38 131.7 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KII93270.1 - 6.2e-17 61.4 0.0 1.4e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 KII93270.1 - 6.9e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Pkinase PF00069.20 KII93271.1 - 3e-72 242.8 0.0 3.7e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93271.1 - 3.5e-31 108.2 0.0 4.5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII93271.1 - 0.00029 19.9 0.0 0.0008 18.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII93271.1 - 0.0006 19.6 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KII93271.1 - 0.003 16.5 0.0 0.022 13.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KII93271.1 - 0.016 14.5 0.1 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family NAD_binding_1 PF00175.16 KII93272.1 - 1.3e-24 86.8 0.0 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KII93272.1 - 4.7e-17 61.9 0.0 9e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KII93272.1 - 1.1e-06 28.6 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KII93272.1 - 0.00072 19.5 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain UCH PF00443.24 KII93273.1 - 1.1e-45 155.8 0.0 5e-45 153.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KII93273.1 - 1.6e-23 81.8 4.2 8e-18 63.6 0.1 3.0 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.1 KII93273.1 - 4.5e-12 46.0 0.0 2.2e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DivIC PF04977.10 KII93273.1 - 0.26 10.7 1.4 0.68 9.4 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator Apolipoprotein PF01442.13 KII93273.1 - 0.27 10.7 4.7 4.6 6.6 0.4 2.3 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain HSBP1 PF06825.7 KII93277.1 - 0.016 14.7 0.8 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tropomyosin PF00261.15 KII93277.1 - 0.019 14.0 0.1 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Tropomyosin Med21 PF11221.3 KII93277.1 - 0.02 14.8 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex CHASE3 PF05227.8 KII93277.1 - 0.078 12.6 0.4 0.62 9.7 0.3 1.9 1 1 0 1 1 1 0 CHASE3 domain efThoc1 PF11957.3 KII93278.1 - 4.6e-98 328.8 1.3 1.5e-93 313.9 0.1 2.2 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.16 KII93278.1 - 1.9e-42 145.3 0.0 8.4e-42 143.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KII93278.1 - 8e-25 86.5 0.1 2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KII93278.1 - 2.1e-10 39.7 0.0 5.2e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KII93278.1 - 2.9e-10 39.5 0.3 1.3e-09 37.4 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KII93278.1 - 4.5e-10 38.8 0.1 6.7e-09 35.0 0.1 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KII93278.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII93278.1 - 9.8e-07 28.6 0.0 3.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 KII93278.1 - 1.9e-06 26.9 0.0 3.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KII93278.1 - 0.0011 18.9 0.0 0.011 15.6 0.0 2.4 2 1 0 2 2 1 1 NADH(P)-binding DapB_N PF01113.15 KII93278.1 - 0.0019 18.0 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KII93278.1 - 0.042 13.1 0.2 1.4 8.0 0.0 2.5 3 0 0 3 3 3 0 NmrA-like family Ldh_1_N PF00056.18 KII93278.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Tuberin PF03542.11 KII93278.1 - 0.29 10.1 0.0 0.48 9.4 0.0 1.2 1 0 0 1 1 1 0 Tuberin MFS_1 PF07690.11 KII93279.1 - 2.4e-38 131.7 24.1 2.4e-38 131.7 16.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4246 PF14033.1 KII93280.1 - 8.5e-94 314.9 0.0 3.1e-92 309.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) DUF515 PF04415.7 KII93280.1 - 0.29 9.3 0.0 0.44 8.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Rotamase PF00639.16 KII93281.1 - 1.6e-22 80.0 0.0 2.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KII93281.1 - 2.6e-18 66.3 0.0 3.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KII93281.1 - 6.1e-07 29.1 0.6 1e-06 28.4 0.1 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KII93281.1 - 0.00036 21.1 0.0 0.0005 20.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MOSC_N PF03476.11 KII93282.1 - 4.6e-16 58.6 0.0 7.1e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KII93282.1 - 3.5e-15 55.6 0.0 6.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 MOSC domain UCH PF00443.24 KII93283.1 - 8.5e-64 215.2 0.0 1.1e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII93283.1 - 6.1e-34 117.8 0.3 4.7e-25 88.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ADH_zinc_N PF00107.21 KII93285.1 - 4.6e-35 120.0 0.0 9.1e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII93285.1 - 4.7e-17 63.0 0.0 9.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII93285.1 - 9.6e-09 34.9 0.1 5.3e-07 29.3 0.0 2.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KII93285.1 - 0.019 14.9 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Peripla_BP_6 PF13458.1 KII93285.1 - 0.023 14.0 0.3 2.1 7.6 0.0 2.7 2 1 1 3 3 3 0 Periplasmic binding protein adh_short PF00106.20 KII93286.1 - 2.6e-16 60.0 0.2 4.4e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII93286.1 - 2e-09 37.5 0.1 2.6e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII93286.1 - 2.1e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII93286.1 - 0.00076 18.9 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Y_phosphatase PF00102.22 KII93287.1 - 1.1e-35 123.0 0.0 3.9e-19 68.9 0.0 3.0 3 0 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KII93287.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate F5_F8_type_C PF00754.20 KII93288.1 - 6.7e-05 22.7 0.0 7.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 KII93288.1 - 0.0056 16.2 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) O-FucT PF10250.4 KII93291.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase MFS_1 PF07690.11 KII93292.1 - 1.2e-49 168.9 19.2 1.2e-49 168.9 13.3 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII93292.1 - 1.3e-16 60.2 6.7 1.3e-16 60.2 4.7 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KII93292.1 - 8.3e-10 37.4 2.4 1.2e-09 36.9 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KII93292.1 - 1.6e-08 33.4 5.1 1.6e-08 33.4 3.5 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein ATG22 PF11700.3 KII93292.1 - 2.1e-05 23.2 1.9 2.1e-05 23.2 1.3 3.1 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 KII93292.1 - 7.5e-05 21.0 5.7 7.5e-05 21.0 3.9 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 KII93292.1 - 0.003 17.3 0.2 0.003 17.3 0.1 2.7 3 0 0 3 3 3 1 MFS_1 like family F-box-like PF12937.2 KII93293.1 - 1.5e-07 31.0 2.3 2.7e-07 30.1 1.6 1.5 1 0 0 1 1 1 1 F-box-like Chromo PF00385.19 KII93300.1 - 1.2e-15 56.9 0.4 1.3e-15 56.8 0.2 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KII93300.1 - 0.12 12.1 1.6 0.14 11.8 1.1 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF4413 PF14372.1 KII93301.1 - 0.026 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Asp_protease_2 PF13650.1 KII93302.1 - 0.066 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.1 KII93302.1 - 0.14 11.8 0.7 0.41 10.3 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle Transposase_21 PF02992.9 KII93303.1 - 1e-09 37.8 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KII93303.1 - 1.9e-07 30.5 0.0 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PUL PF08324.6 KII93303.1 - 0.096 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 PUL domain DUF3678 PF12435.3 KII93304.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF4535 PF15054.1 KII93304.1 - 0.22 10.9 0.6 0.44 9.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) zf-MYND PF01753.13 KII93305.1 - 3.2e-09 36.5 11.0 5.7e-09 35.7 7.7 1.4 1 0 0 1 1 1 1 MYND finger DUF3984 PF13136.1 KII93305.1 - 0.11 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Ecl1 PF12855.2 KII93305.1 - 0.28 10.5 4.6 0.6 9.4 3.2 1.6 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KII93306.1 - 3e-09 36.5 10.7 5.5e-09 35.7 7.4 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KII93306.1 - 0.075 12.3 2.6 0.18 11.1 1.8 1.6 1 0 0 1 1 1 0 Life-span regulatory factor Cation_efflux PF01545.16 KII93308.1 - 1.1e-33 116.5 3.1 1.4e-33 116.1 2.1 1.1 1 0 0 1 1 1 1 Cation efflux family Herpes_UL20 PF04544.7 KII93309.1 - 0.024 14.4 0.9 0.078 12.7 0.6 1.8 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 7tm_2 PF00002.19 KII93309.1 - 1 8.3 9.5 0.073 12.1 1.7 2.4 3 0 0 3 3 3 0 7 transmembrane receptor (Secretin family) Pkinase PF00069.20 KII93310.1 - 3.2e-70 236.2 0.0 4.4e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93310.1 - 8.7e-52 175.7 0.0 1.2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93310.1 - 0.00011 21.2 0.0 0.00074 18.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KII93310.1 - 0.0043 16.3 0.5 0.0076 15.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Adaptin_N PF01602.15 KII93311.1 - 1.6e-109 366.6 0.0 2.1e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KII93311.1 - 8.4e-09 35.6 6.5 0.00034 20.8 0.0 5.2 4 3 2 6 6 6 4 HEAT repeats Cnd1 PF12717.2 KII93311.1 - 1.3e-07 31.6 0.0 0.00082 19.2 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KII93311.1 - 1.3e-05 24.8 2.4 4.2 7.7 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Nipped-B_C PF12830.2 KII93311.1 - 0.00047 19.8 0.2 3.8 7.1 0.0 3.5 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.1 KII93311.1 - 0.00077 19.8 10.9 0.28 11.7 0.0 6.8 6 2 2 8 8 8 1 HEAT-like repeat DUF2435 PF10363.4 KII93311.1 - 0.0072 16.1 0.9 4.3 7.2 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) Arm PF00514.18 KII93311.1 - 0.0094 15.7 0.2 22 5.0 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 KII93311.1 - 0.048 13.6 0.0 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RabGAP-TBC PF00566.13 KII93312.1 - 5.3e-45 153.5 0.0 7.3e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNase_H PF00075.19 KII93313.1 - 4.7e-26 91.6 0.0 1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 KII93313.1 - 1.3e-15 57.1 0.3 2.8e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Myco_19_kDa PF05481.7 KII93313.1 - 0.051 13.4 2.7 0.096 12.5 1.9 1.4 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Dysbindin PF04440.11 KII93313.1 - 1.2 8.9 5.3 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) DDRGK PF09756.4 KII93315.1 - 0.1 12.0 10.3 0.13 11.6 7.1 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4551 PF15087.1 KII93315.1 - 0.4 8.9 1.8 0.44 8.8 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PIH1 PF08190.7 KII93315.1 - 2.4 7.5 7.8 2.8 7.2 5.4 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 NARP1 PF12569.3 KII93315.1 - 2.6 6.6 8.1 2.9 6.5 5.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MIP-T3 PF10243.4 KII93315.1 - 5.3 5.3 18.7 6.1 5.1 12.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ING PF12998.2 KII93319.1 - 2.1e-13 50.4 0.1 3.2e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KII93319.1 - 3.7e-09 36.1 8.4 6.2e-09 35.4 5.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KII93319.1 - 0.17 11.2 3.7 0.31 10.3 2.6 1.4 1 0 0 1 1 1 0 PHD-finger DUF605 PF04652.11 KII93319.1 - 5.4 6.3 13.6 8.1 5.7 9.4 1.2 1 0 0 1 1 1 0 Vta1 like Fip1 PF05182.8 KII93320.1 - 2.9e-21 74.4 0.3 4.7e-21 73.7 0.2 1.4 1 0 0 1 1 1 1 Fip1 motif Pentapeptide_2 PF01469.13 KII93320.1 - 0.00065 19.2 0.0 0.00065 19.2 0.0 2.6 2 1 1 3 3 3 1 Pentapeptide repeats (8 copies) RIC1 PF07064.8 KII93321.1 - 1.7e-76 257.1 0.1 2.4e-76 256.6 0.1 1.2 1 0 0 1 1 1 1 RIC1 PRELI PF04707.9 KII93322.1 - 3.1e-36 124.2 0.0 3.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.6 KII93322.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) DUF2370 PF10176.4 KII93323.1 - 1e-65 221.3 0.0 1.3e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 KII93323.1 - 0.074 13.2 0.7 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Mpv17_PMP22 PF04117.7 KII93324.1 - 6.2e-26 89.8 0.6 9.2e-26 89.2 0.4 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family AA_permease PF00324.16 KII93326.1 - 1.9e-122 409.0 34.2 2.3e-122 408.7 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII93326.1 - 3.3e-35 121.4 38.2 4e-35 121.1 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease Vac_ImportDeg PF09783.4 KII93327.1 - 0.039 13.4 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Vacuolar import and degradation protein BNR PF02012.15 KII93331.1 - 1.9e-10 38.9 33.5 0.95 9.5 0.0 9.4 9 0 0 9 9 9 7 BNR/Asp-box repeat LRR_4 PF12799.2 KII93332.1 - 4.9e-15 54.7 13.1 0.00017 21.1 0.0 6.8 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII93332.1 - 8.3e-07 28.6 10.3 0.071 12.8 0.2 5.9 4 2 2 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KII93332.1 - 6.6e-05 22.5 10.8 1.9 8.8 0.0 6.9 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 KII93332.1 - 0.11 12.5 7.7 1.8e+02 2.8 0.0 7.1 9 0 0 9 9 9 0 Leucine Rich Repeat DUF3755 PF12579.3 KII93333.1 - 0.04 13.3 0.5 0.19 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) RhoGEF PF00621.15 KII93334.1 - 1.4e-45 155.3 0.0 2.3e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 KII93334.1 - 1.1e-11 44.0 2.8 4.9e-05 22.8 0.1 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII93334.1 - 8.4e-11 41.4 1.8 4.8e-06 26.2 0.4 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KII93334.1 - 0.0011 18.6 3.0 7.6 7.0 0.2 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KII93334.1 - 0.0035 17.2 2.6 19 6.0 0.1 5.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 KII93334.1 - 0.093 12.8 0.1 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat PAXNEB PF05625.6 KII93335.1 - 9.4e-59 199.0 0.0 1.2e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein Glyco_hydro_100 PF12899.2 KII93335.1 - 0.089 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase Peptidase_S24 PF00717.18 KII93336.1 - 1.2e-07 31.1 0.0 2.7e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 KII93336.1 - 5.4e-06 25.9 0.1 0.002 17.6 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_11 PF13414.1 KII93337.1 - 1.6e-12 46.8 2.4 2.5e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KII93337.1 - 2.2e-09 36.5 0.4 0.0025 17.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII93337.1 - 5.6e-09 35.2 1.0 0.00042 19.8 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII93337.1 - 0.00066 19.5 2.5 0.77 9.7 0.1 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII93337.1 - 0.0018 18.9 0.8 0.32 11.7 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII93337.1 - 0.0019 17.8 0.2 0.085 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KII93337.1 - 0.036 13.5 0.0 0.73 9.2 0.0 2.4 2 1 1 3 3 3 0 Foie gras liver health family 1 TPR_8 PF13181.1 KII93337.1 - 0.058 13.2 0.0 8.3 6.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII93337.1 - 0.085 13.5 3.9 0.98 10.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 KII93338.1 - 1.2e-19 70.8 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII93338.1 - 3.5e-07 30.2 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII93338.1 - 8e-07 28.8 0.0 5e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KII93338.1 - 0.00052 19.5 0.0 0.0016 17.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KII93338.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_N PF05222.10 KII93339.1 - 2.7e-27 95.4 0.0 4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KII93339.1 - 3.4e-14 52.7 0.0 5.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2360 PF10152.4 KII93341.1 - 0.86 9.8 4.9 0.23 11.7 1.1 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-Tim10_DDP PF02953.10 KII93342.1 - 1.4e-21 75.5 1.8 1.7e-21 75.2 1.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.16 KII93343.1 - 1.7e-21 76.0 0.0 2.7e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Aa_trans PF01490.13 KII93344.1 - 9.1e-35 119.9 37.3 1e-34 119.7 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bap31 PF05529.7 KII93344.1 - 0.24 10.8 0.4 0.68 9.3 0.3 1.8 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Abhydrolase_6 PF12697.2 KII93345.1 - 4.8e-16 59.3 0.4 8e-11 42.2 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family PBP1_TM PF14812.1 KII93345.1 - 5.2 7.4 8.0 19 5.6 5.5 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_gE PF02480.11 KII93346.1 - 0.0059 14.9 0.0 0.0095 14.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Sensor PF13796.1 KII93346.1 - 0.031 13.8 0.3 0.06 12.9 0.2 1.4 1 0 0 1 1 1 0 Putative sensor DAP10 PF07213.6 KII93346.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.1 KII93346.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family Tad PF13400.1 KII93346.1 - 4.5 7.3 7.6 0.87 9.6 2.9 1.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Septin PF00735.13 KII93349.1 - 2.8e-107 357.9 0.0 4.7e-107 357.2 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KII93349.1 - 7.7e-06 25.8 0.0 2e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KII93349.1 - 7.4e-05 22.6 2.4 0.092 12.5 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KII93349.1 - 0.0033 16.6 0.3 0.017 14.2 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KII93349.1 - 0.0034 18.1 1.6 0.021 15.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 KII93349.1 - 0.0069 16.8 0.4 0.028 14.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KII93349.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KII93349.1 - 0.019 14.4 0.0 0.25 10.7 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KII93349.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.8 KII93349.1 - 0.085 11.6 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.1 KII93349.1 - 0.098 12.5 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KII93350.1 - 1.5e-107 358.8 0.2 2.2e-107 358.2 0.0 1.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KII93350.1 - 8.9e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KII93350.1 - 0.0023 17.7 1.7 0.69 9.7 0.0 2.8 3 0 0 3 3 3 2 Dynamin family DUF258 PF03193.11 KII93350.1 - 0.0025 17.0 0.3 0.011 14.9 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KII93350.1 - 0.0027 17.1 0.1 0.04 13.3 0.0 2.4 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KII93350.1 - 0.0041 17.9 1.9 0.011 16.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KII93350.1 - 0.014 14.8 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 KII93350.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 KII93350.1 - 0.015 15.8 0.1 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein IIGP PF05049.8 KII93350.1 - 0.073 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.1 KII93350.1 - 0.082 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KII93350.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gasdermin PF04598.7 KII93350.1 - 0.48 9.1 5.5 1.1 7.9 3.9 1.5 1 1 0 1 1 1 0 Gasdermin family MutS_V PF00488.16 KII93351.1 - 1.2e-80 270.3 0.0 3e-80 269.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KII93351.1 - 2.1e-42 145.2 1.2 6e-42 143.7 0.8 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KII93351.1 - 5.3e-23 81.2 0.0 1.1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KII93351.1 - 1.2e-08 35.0 0.1 4.8e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_23 PF13476.1 KII93351.1 - 0.0037 17.6 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII93351.1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KII93351.1 - 0.13 12.2 0.0 0.46 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain MutS_IV PF05190.13 KII93351.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV Aconitase PF00330.15 KII93352.1 - 1.3e-157 525.0 0.0 1.3e-156 521.7 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KII93352.1 - 2.1e-35 121.6 0.0 3.6e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Oxysterol_BP PF01237.13 KII93353.1 - 4.6e-103 344.4 0.0 8.8e-103 343.4 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KII93353.1 - 2.8e-16 59.3 0.0 1.3e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SPO22 PF08631.5 KII93353.1 - 0.00037 19.6 0.0 0.00089 18.4 0.0 1.5 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like PH_11 PF15413.1 KII93353.1 - 0.00099 19.3 0.2 0.062 13.5 0.1 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KII93353.1 - 0.012 15.8 0.2 0.24 11.6 0.1 2.7 1 1 0 1 1 1 0 PH domain Glyco_hydro_3 PF00933.16 KII93354.1 - 9.5e-84 280.8 0.1 1.4e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII93354.1 - 1.3e-62 211.2 2.1 7.8e-62 208.7 1.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII93354.1 - 6.9e-21 73.9 0.1 1.3e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pantoate_transf PF02548.10 KII93355.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase 6PGD PF00393.14 KII93358.1 - 1.2e-131 438.2 0.0 1.5e-131 437.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KII93358.1 - 7e-52 175.5 0.0 1e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KII93358.1 - 0.0066 16.8 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KII93358.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Asn_synthase PF00733.16 KII93359.1 - 3.1e-53 180.8 0.0 4.6e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KII93359.1 - 5.2e-08 32.6 0.0 1.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.8 KII93359.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.20 KII93360.1 - 4.4e-24 85.3 2.6 5e-24 85.1 0.9 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2522 PF10747.4 KII93360.1 - 0.051 13.6 0.5 0.088 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2522) MgtE_N PF03448.12 KII93360.1 - 0.13 12.5 2.3 3 8.2 0.0 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain COesterase PF00135.23 KII93361.1 - 6.9e-102 341.8 0.0 1.1e-101 341.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII93361.1 - 0.00084 18.9 0.0 0.0022 17.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII93361.1 - 0.038 13.1 0.2 0.094 11.9 0.2 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family RRM_1 PF00076.17 KII93362.1 - 2e-54 181.0 0.0 1.8e-19 69.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII93362.1 - 1.1e-39 134.1 0.0 5.8e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII93362.1 - 3.9e-25 87.4 0.0 8.3e-08 31.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.5 KII93362.1 - 0.00056 19.8 0.0 1.2 9.1 0.0 2.7 2 1 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.1 KII93362.1 - 0.0053 16.5 0.0 4.2 7.2 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif NAD_binding_10 PF13460.1 KII93363.1 - 1.7e-09 37.9 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII93363.1 - 7.3e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF2866 PF11065.3 KII93363.1 - 0.039 13.8 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) ApbA PF02558.11 KII93363.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_72 PF03198.9 KII93364.1 - 9.8e-89 297.4 0.0 1.3e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KII93364.1 - 4.9e-21 75.0 1.5 1.4e-20 73.5 1.0 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 KII93364.1 - 0.0019 17.4 0.0 0.021 14.0 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.17 KII93365.1 - 4.5e-15 55.0 0.1 6.4e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII93365.1 - 1.7e-11 43.9 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII93365.1 - 1.2e-08 34.6 0.1 1.7e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 KII93365.1 - 4.1e-08 32.7 3.0 6.8e-08 32.0 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KII93365.1 - 0.00018 21.1 0.3 0.00046 19.8 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KII93365.1 - 0.00049 19.7 0.1 0.00092 18.8 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_3 PF08777.6 KII93365.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif RNA_bind PF08675.6 KII93365.1 - 0.058 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain HrpA_pilin PF09589.5 KII93366.1 - 0.00087 19.6 1.6 0.35 11.2 2.1 2.1 2 0 0 2 2 2 2 HrpA pilus formation protein HSP9_HSP12 PF04119.7 KII93366.1 - 0.011 15.7 3.1 0.18 11.8 0.2 2.6 1 1 1 2 2 2 0 Heat shock protein 9/12 DUF650 PF04894.7 KII93366.1 - 0.026 13.9 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF650) TFIIF_alpha PF05793.7 KII93366.1 - 0.44 8.8 7.7 0.51 8.6 5.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med6 PF04934.9 KII93367.1 - 4.6e-41 139.6 0.2 6.6e-41 139.1 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF3643 PF12356.3 KII93367.1 - 0.15 11.4 0.3 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3643) Clat_adaptor_s PF01217.15 KII93368.1 - 4.4e-44 149.6 0.1 1.1e-43 148.4 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain SGT1 PF07093.6 KII93369.1 - 9e-142 473.4 9.1 5.4e-129 431.2 0.0 2.3 2 0 0 2 2 2 2 SGT1 protein p450 PF00067.17 KII93370.1 - 1.8e-73 247.6 0.0 3.9e-73 246.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII93371.1 - 4.9e-72 242.9 0.0 1.5e-71 241.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 PAT1 PF09770.4 KII93372.1 - 0.092 10.9 15.4 0.11 10.7 10.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_pol_A_exo1 PF01612.15 KII93373.1 - 1.2e-21 76.9 0.0 1.4e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease F1F0-ATPsyn_F PF10791.4 KII93373.1 - 0.069 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Glyco_hydro_18 PF00704.23 KII93374.1 - 6.8e-17 61.9 5.3 1.3e-16 61.0 3.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 RAP1 PF07218.6 KII93374.1 - 0.23 9.5 7.6 0.31 9.0 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CBM_5_12 PF02839.9 KII93375.1 - 1.3e-09 37.4 10.9 4.3e-09 35.8 7.5 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_18 PF00704.23 KII93375.1 - 5.5e-07 29.3 1.8 7.7e-07 28.8 1.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 KII93376.1 - 2.2e-58 197.4 0.1 2.6e-58 197.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93376.1 - 1.2e-20 73.6 0.0 1.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII93376.1 - 1.2e-07 31.7 0.0 3.6e-05 23.6 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII93376.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KII93376.1 - 0.051 12.9 0.3 6 6.1 0.0 2.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Aconitase_B_N PF11791.3 KII93376.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Aconitate B N-terminal domain Kdo PF06293.9 KII93376.1 - 0.096 11.7 0.3 0.18 10.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.23 KII93377.1 - 7.1e-05 23.1 0.0 0.18 12.0 0.0 2.7 1 1 1 2 2 2 2 SET domain CTDII PF01556.13 KII93379.1 - 1.3e-26 92.3 0.2 1.6e-22 79.1 0.0 3.3 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KII93379.1 - 2.7e-24 84.6 1.4 4.3e-24 84.0 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KII93379.1 - 6.6e-10 38.8 19.3 9.4e-10 38.4 12.6 1.9 2 0 0 2 2 2 1 DnaJ central domain MFS_1 PF07690.11 KII93380.1 - 5.3e-43 147.0 53.0 2.5e-32 111.9 21.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KII93380.1 - 3.8e-10 38.6 14.8 3.8e-10 38.6 10.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 KII93380.1 - 0.045 13.6 0.6 0.045 13.6 0.4 3.0 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Choline_kinase PF01633.15 KII93381.1 - 9.8e-50 169.0 0.0 1.3e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KII93381.1 - 1.3e-12 48.0 0.1 1.9e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-CCCH PF00642.19 KII93382.1 - 6e-20 70.4 14.2 1.4e-11 43.8 1.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII93382.1 - 0.076 13.0 0.4 0.076 13.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3437 PF11919.3 KII93383.1 - 7e-31 105.7 0.2 3.3e-30 103.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KII93383.1 - 1.3e-07 31.0 1.1 0.0016 18.3 0.1 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KII93383.1 - 0.00035 20.8 3.7 0.015 15.5 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.2 KII93383.1 - 0.0073 16.6 0.3 0.38 11.1 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KII93383.1 - 0.022 15.2 1.4 0.55 10.7 0.1 4.2 4 1 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.2 KII93383.1 - 0.036 13.9 0.2 5.8 6.7 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 API5 PF05918.6 KII93383.1 - 0.19 10.2 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Chalcone PF02431.10 KII93384.1 - 3.6e-28 98.3 0.0 1.4e-27 96.4 0.0 1.8 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Histone PF00125.19 KII93385.1 - 4.2e-30 103.6 0.8 6.6e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII93385.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KII93385.1 - 0.0013 18.7 1.4 0.0013 18.7 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KII93385.1 - 0.015 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KII93385.1 - 0.17 11.1 1.5 0.18 11.0 1.1 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T zf-C3HC4 PF00097.20 KII93386.1 - 1.7e-06 27.6 10.0 2.5e-06 27.0 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII93386.1 - 7.5e-06 25.5 7.5 1.2e-05 24.9 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII93386.1 - 1e-05 25.4 11.2 1.6e-05 24.8 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII93386.1 - 1.6e-05 24.6 10.6 2.5e-05 23.9 7.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KII93386.1 - 0.0088 15.7 10.2 0.02 14.6 7.2 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII93386.1 - 0.013 15.4 10.8 0.024 14.4 7.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KII93386.1 - 0.02 14.7 4.9 0.043 13.6 3.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KII93386.1 - 0.21 11.7 7.8 0.7 10.0 5.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DZR PF12773.2 KII93386.1 - 0.22 11.3 8.2 0.56 10.0 5.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon Baculo_IE-1 PF05290.6 KII93386.1 - 0.37 10.4 2.1 0.58 9.8 1.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.1 KII93386.1 - 2.8 7.7 6.0 6.2 6.6 4.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.16 KII93386.1 - 6.1 6.8 8.6 18 5.3 6.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger ATP-synt_F PF01990.12 KII93387.1 - 3.6e-32 110.6 0.1 4.1e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 KII93387.1 - 0.034 13.0 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TIM21 PF08294.6 KII93388.1 - 1.8e-23 82.8 0.0 6.1e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 TIM21 DUF4218 PF13960.1 KII93390.1 - 1.2e-06 28.0 0.0 1.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 KII93391.1 - 4.1e-08 32.6 0.0 2.9e-07 29.8 0.0 2.0 1 1 0 2 2 2 1 Transposase family tnp2 Transposase_21 PF02992.9 KII93392.1 - 2.3e-06 26.8 0.3 2.3e-06 26.8 0.2 1.7 2 0 0 2 2 2 1 Transposase family tnp2 S-antigen PF05756.6 KII93393.1 - 0.31 11.0 1.7 0.43 10.5 1.2 1.3 1 0 0 1 1 1 0 S-antigen protein PBP1_TM PF14812.1 KII93393.1 - 0.5 10.7 2.8 0.83 10.0 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Choline_sulf_C PF12411.3 KII93393.1 - 1.8 8.4 4.5 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal Mito_fiss_reg PF05308.6 KII93394.1 - 0.085 12.2 3.5 0.16 11.3 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Translin PF01997.11 KII93395.1 - 8.9e-52 175.5 0.0 1.1e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Translin family DcpS_C PF11969.3 KII93396.1 - 0.0034 17.5 1.2 0.014 15.6 0.9 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3437 PF11919.3 KII93397.1 - 1.5e-13 50.2 0.0 9.5e-13 47.6 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KII93397.1 - 4e-08 32.6 3.4 0.036 14.1 0.0 7.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 KII93397.1 - 1.4e-06 28.5 0.5 0.031 14.5 0.0 5.7 5 1 1 6 6 6 1 HEAT repeats Cnd1 PF12717.2 KII93397.1 - 0.016 15.0 0.6 1.4 8.7 0.1 3.8 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KII93397.1 - 0.067 13.5 0.0 38 4.7 0.0 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KII93397.1 - 0.28 11.7 4.9 9.2 6.8 0.0 5.1 4 1 1 5 5 5 0 HEAT-like repeat TMF_TATA_bd PF12325.3 KII93398.1 - 0.072 12.8 1.2 0.16 11.7 0.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BATS PF06968.8 KII93400.1 - 5e-28 96.7 0.0 1.5e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KII93400.1 - 5.9e-16 59.0 0.0 9.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily BTG PF07742.7 KII93406.1 - 1.4e-12 47.2 0.0 2.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 BTG family VGCC_beta4Aa_N PF12052.3 KII93406.1 - 1.1 9.2 6.9 0.25 11.2 0.3 2.3 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ribosomal_S27e PF01667.12 KII93407.1 - 1.1e-29 101.6 3.7 1.4e-29 101.4 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KII93407.1 - 0.004 16.9 1.4 0.0047 16.7 1.0 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 KII93407.1 - 0.28 10.5 1.7 0.43 9.9 1.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding 4HBT_3 PF13622.1 KII93408.1 - 1.5e-36 126.4 0.0 2.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily XPA_C PF05181.7 KII93408.1 - 1.5e-27 94.9 1.7 2.5e-27 94.1 1.2 1.4 1 0 0 1 1 1 1 XPA protein C-terminus Acyl_CoA_thio PF02551.10 KII93408.1 - 6e-24 84.1 0.0 1.5e-18 66.7 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase XPA_N PF01286.13 KII93408.1 - 0.00025 20.6 3.4 0.0008 19.0 2.4 1.9 1 0 0 1 1 1 1 XPA protein N-terminal DUF1977 PF09320.6 KII93408.1 - 0.046 13.9 6.0 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1977) M-factor PF03855.8 KII93408.1 - 0.2 11.6 1.2 0.45 10.5 0.8 1.6 1 0 0 1 1 1 0 M-factor ZZ PF00569.12 KII93409.1 - 9.5e-26 89.0 40.0 8.3e-10 38.0 4.4 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type PB1 PF00564.19 KII93409.1 - 0.2 11.3 0.0 0.52 10.0 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Chromo PF00385.19 KII93411.1 - 9.8e-05 21.9 1.3 0.00021 20.9 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ZZ PF00569.12 KII93412.1 - 9.3e-30 101.9 49.6 8.5e-11 41.2 7.3 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type Aminotran_4 PF01063.14 KII93413.1 - 4e-27 95.1 0.0 5.2e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ZZ PF00569.12 KII93414.1 - 4e-09 35.8 25.3 2.2e-07 30.2 4.2 2.7 3 0 0 3 3 3 2 Zinc finger, ZZ type F-box-like PF12937.2 KII93415.1 - 5.7e-06 25.9 0.3 1.4e-05 24.6 0.2 1.7 1 1 0 1 1 1 1 F-box-like DUF2824 PF11039.3 KII93416.1 - 0.029 14.0 0.2 0.059 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) WD40 PF00400.27 KII93417.1 - 2.3e-76 249.1 20.7 1.2e-08 34.4 0.1 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 KII93417.1 - 1.6e-39 134.7 0.0 2.3e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Cytochrom_D1 PF02239.11 KII93417.1 - 0.0047 15.2 0.1 0.11 10.7 0.0 2.5 3 0 0 3 3 3 1 Cytochrome D1 heme domain VID27 PF08553.5 KII93417.1 - 0.17 10.0 0.1 0.44 8.7 0.0 1.6 2 0 0 2 2 2 0 VID27 cytoplasmic protein Fork_head PF00250.13 KII93419.1 - 1.5e-21 76.2 0.0 1.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Fork head domain CBS PF00571.23 KII93420.1 - 7e-36 121.7 8.0 1.1e-08 34.6 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KII93420.1 - 8.1e-09 35.0 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain MerC PF03203.9 KII93421.1 - 0.029 14.7 0.3 0.033 14.5 0.2 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein Corona_RPol_N PF06478.8 KII93421.1 - 0.1 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus UPF0121 PF03661.8 KII93422.1 - 1.1e-20 73.9 0.7 1.3e-20 73.6 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DEAD PF00270.24 KII93423.1 - 1.6e-42 144.9 0.0 2.7e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII93423.1 - 2.1e-21 75.5 0.0 4.4e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KII93423.1 - 1.4e-19 69.3 0.3 3.2e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Trypan_PARP PF05887.6 KII93423.1 - 0.15 11.8 1.6 0.28 10.9 1.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTH2 PF01981.11 KII93424.1 - 1.6e-45 153.5 0.1 2.3e-45 153.0 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PhzC-PhzF PF02567.11 KII93424.1 - 0.07 12.3 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Sigma70_ner PF04546.8 KII93424.1 - 1.2 8.7 5.0 0.48 10.0 1.6 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 KII93424.1 - 3.6 5.2 6.9 4.8 4.8 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Chromo PF00385.19 KII93426.1 - 1.3e-08 34.3 0.2 2.3e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kinesin PF00225.18 KII93427.1 - 1.5e-56 191.5 0.0 2.1e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 KII93427.1 - 0.055 13.6 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KII93427.1 - 0.1 12.3 0.3 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 GST_N_3 PF13417.1 KII93428.1 - 6.1e-11 42.3 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII93428.1 - 1.8e-05 24.6 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KII93428.1 - 9.3e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII93428.1 - 0.055 13.3 0.3 0.15 11.9 0.2 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Colicin_im PF03857.8 KII93428.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein NfeD PF01957.13 KII93429.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding CopD PF05425.8 KII93429.1 - 0.059 13.5 0.3 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Copper resistance protein D B12D PF06522.6 KII93429.1 - 0.14 11.8 0.1 0.9 9.2 0.1 2.2 2 1 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF4231 PF14015.1 KII93429.1 - 0.19 11.6 1.4 0.33 10.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Pkinase PF00069.20 KII93430.1 - 0.0098 15.0 0.1 0.061 12.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93430.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DNase_NucA_NucB PF14040.1 KII93431.1 - 2.2e-09 37.4 2.9 3.5e-08 33.5 0.3 2.7 2 1 0 2 2 2 2 Deoxyribonuclease NucA/NucB WD40 PF00400.27 KII93432.1 - 1.9e-08 33.8 28.3 0.17 11.7 0.1 9.3 10 0 0 10 10 10 5 WD domain, G-beta repeat zf-Tim10_DDP PF02953.10 KII93433.1 - 4e-24 83.6 0.9 4.5e-24 83.5 0.6 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger zf-met2 PF12907.2 KII93434.1 - 2.7e-15 56.0 4.0 3.5e-15 55.6 2.7 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KII93434.1 - 4.8e-06 27.1 13.7 4.8e-06 27.1 9.5 1.8 2 0 0 2 2 2 1 4F5 protein family Beta_elim_lyase PF01212.16 KII93435.1 - 6.7e-68 228.9 0.0 8.9e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KII93435.1 - 9.9e-06 24.7 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KII93435.1 - 0.0036 15.6 0.0 0.0061 14.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KII93435.1 - 0.0066 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Urb2 PF10441.4 KII93436.1 - 5.3e-32 111.2 0.4 2.6e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 Urb2/Npa2 family RWD PF05773.17 KII93437.1 - 2.1e-15 56.6 0.0 3.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KII93437.1 - 1.2e-13 50.7 40.7 1.6e-09 37.4 2.4 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KII93437.1 - 2.6e-06 27.1 6.7 2.6e-06 27.1 4.7 4.1 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KII93437.1 - 0.00089 18.8 4.6 0.00089 18.8 3.2 4.6 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII93437.1 - 0.0023 17.6 6.6 0.0023 17.6 4.6 4.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII93437.1 - 0.019 14.9 7.6 0.019 14.9 5.3 4.8 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KII93437.1 - 5.7 6.8 24.1 0.046 13.6 3.6 3.4 3 0 0 3 3 3 0 FYVE-type zinc finger KH_1 PF00013.24 KII93438.1 - 1.2e-34 117.7 0.6 1.7e-08 33.9 0.0 6.2 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 KII93438.1 - 1.6e-23 81.8 2.7 6.8e-06 25.5 0.1 6.7 6 0 0 6 6 6 4 KH domain V-ATPase_C PF03223.10 KII93439.1 - 1e-118 396.5 1.9 1.1e-118 396.3 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Rhodanese PF00581.15 KII93440.1 - 1.3e-21 76.9 0.0 2.1e-12 47.3 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain Ctr PF04145.10 KII93445.1 - 1.8e-28 99.4 0.2 2.7e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family CobS PF02654.10 KII93445.1 - 0.0083 15.7 0.4 0.013 15.1 0.3 1.4 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase Rhodanese PF00581.15 KII93446.1 - 1.2e-16 61.0 0.0 3.1e-16 59.7 0.0 1.7 1 1 1 2 2 2 1 Rhodanese-like domain Multi_ubiq PF14452.1 KII93446.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Multiubiquitin Frataxin_Cyay PF01491.11 KII93447.1 - 3e-32 110.6 0.0 3.8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain WD40 PF00400.27 KII93449.1 - 2.6e-21 74.6 12.6 2.8e-07 30.1 0.5 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KII93449.1 - 0.0059 14.9 0.0 0.012 13.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Bromodomain PF00439.20 KII93450.1 - 1.7e-40 136.8 0.0 1.2e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Spt5_N PF11942.3 KII93450.1 - 1.8 9.1 10.1 4.1 8.0 2.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Cupin_7 PF12973.2 KII93451.1 - 0.0017 18.1 0.1 0.0028 17.4 0.1 1.6 1 1 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.6 KII93451.1 - 0.062 12.8 0.5 0.08 12.4 0.3 1.3 1 1 0 1 1 1 0 Cupin domain G-patch PF01585.18 KII93452.1 - 6.3e-11 41.8 0.2 1.5e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 KII93452.1 - 7.6e-06 25.9 5.9 1.3e-05 25.1 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII93452.1 - 5e-05 23.3 1.4 8.1e-05 22.6 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 KII93452.1 - 7.5e-05 22.5 0.0 7.5e-05 22.5 0.0 2.8 4 0 0 4 4 4 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 KII93452.1 - 0.0017 18.4 0.6 0.0028 17.7 0.4 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Gemini_V1 PF01524.12 KII93452.1 - 0.13 12.2 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Geminivirus V1 protein DUF2335 PF10097.4 KII93452.1 - 0.13 11.8 0.1 0.13 11.8 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) DEAD PF00270.24 KII93453.1 - 1.1e-18 67.3 0.0 3.5e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII93453.1 - 1.7e-17 63.0 0.1 3.6e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII93453.1 - 4.9e-17 62.3 0.0 1.2e-16 61.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KII93453.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.1 KII93453.1 - 0.12 12.5 0.0 0.38 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain RRM_6 PF14259.1 KII93454.1 - 3e-10 39.9 0.0 1.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KII93454.1 - 1.7e-06 27.5 5.6 2.8e-06 26.8 3.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KII93454.1 - 1.8e-06 27.9 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KII93454.1 - 0.00026 20.7 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII93454.1 - 0.0053 16.5 0.1 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.17 KII93454.1 - 0.0057 16.2 0.1 0.035 13.7 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_4 PF01063.14 KII93455.1 - 3.3e-25 88.9 0.0 4.3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Trypsin_2 PF13365.1 KII93456.1 - 8.4e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Glycophorin_A PF01102.13 KII93457.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 3.6 3 1 2 5 5 5 1 Glycophorin A Adeno_E3_CR2 PF02439.10 KII93457.1 - 0.018 14.5 3.3 0.032 13.7 2.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KII93457.1 - 0.16 12.4 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KII93457.1 - 0.83 9.0 7.0 3 7.2 4.8 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ctr PF04145.10 KII93457.1 - 1.5 8.8 4.2 2.3 8.2 0.0 2.5 2 2 0 2 2 2 0 Ctr copper transporter family PXA PF02194.10 KII93458.1 - 4.7e-30 104.5 0.0 7.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 PXA domain COX15-CtaA PF02628.10 KII93458.1 - 0.014 14.3 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Glucosamine_iso PF01182.15 KII93459.1 - 2.6e-63 213.3 0.0 3.1e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Chromo PF00385.19 KII93460.1 - 3.3e-11 42.6 0.4 3.3e-11 42.6 0.3 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.17 KII93461.1 - 6e-58 194.8 0.3 7e-58 194.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII93461.1 - 5.1e-19 68.9 0.1 1e-18 67.9 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KII93461.1 - 4.1e-14 52.1 0.1 5.3e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII93461.1 - 4.1e-08 32.6 0.1 5.1e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KII93461.1 - 2.9e-07 30.1 0.0 5e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII93461.1 - 4.2e-07 29.9 0.0 6.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KII93461.1 - 0.0003 20.4 0.5 0.019 14.4 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KII93461.1 - 0.00048 20.2 0.0 0.00092 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KII93461.1 - 0.00053 19.4 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KII93461.1 - 0.00055 19.0 0.4 0.032 13.2 0.0 2.4 2 1 0 2 2 2 1 Septin DUF258 PF03193.11 KII93461.1 - 0.0013 17.9 0.1 0.003 16.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 KII93461.1 - 0.0021 17.5 0.0 0.0081 15.6 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 KII93461.1 - 0.0029 16.8 0.0 0.0049 16.1 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KII93461.1 - 0.0051 16.5 0.2 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 KII93461.1 - 0.0054 16.3 0.2 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KII93461.1 - 0.0077 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KII93461.1 - 0.008 15.9 0.1 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 NTPase AAA_10 PF12846.2 KII93461.1 - 0.014 14.8 0.1 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KII93461.1 - 0.014 15.3 0.1 0.022 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KII93461.1 - 0.014 15.0 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KII93461.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 KII93461.1 - 0.06 12.6 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 KII93461.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KII93461.1 - 0.1 12.9 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter ATG16 PF08614.6 KII93462.1 - 2.2e-44 151.6 19.6 3.2e-44 151.0 13.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 KII93462.1 - 0.022 14.5 22.6 0.035 13.8 6.9 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KII93462.1 - 0.094 12.2 23.5 0.1 12.1 2.1 2.7 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 KII93462.1 - 0.46 9.6 18.9 0.081 12.1 6.9 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.7 KII93462.1 - 0.67 10.1 15.3 1.7 8.8 1.8 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF972 PF06156.8 KII93462.1 - 0.72 10.2 17.2 0.3 11.4 3.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 KII93462.1 - 2 8.4 23.4 0.81 9.7 14.2 1.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ING PF12998.2 KII93462.1 - 3.2 8.0 11.5 1.5 9.1 1.3 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding XhlA PF10779.4 KII93462.1 - 5 7.0 6.9 44 4.0 2.6 2.6 2 0 0 2 2 2 0 Haemolysin XhlA zf-C2H2_4 PF13894.1 KII93464.1 - 2.5e-07 30.5 12.2 0.0004 20.5 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII93464.1 - 2.5e-07 30.6 20.2 1.6e-05 24.9 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII93464.1 - 4.6e-05 23.5 16.0 0.0069 16.6 3.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KII93464.1 - 0.0065 16.5 6.2 0.02 15.0 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KII93464.1 - 2.1 8.1 11.2 0.35 10.6 1.3 2.8 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 KII93464.1 - 3.2 8.1 7.2 0.42 10.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ABC_membrane PF00664.18 KII93465.1 - 4.7e-47 160.7 24.0 1e-24 87.4 3.2 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KII93465.1 - 1.1e-43 148.8 0.0 7.4e-26 91.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII93465.1 - 2.2e-10 40.1 2.1 0.034 13.3 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII93465.1 - 2e-08 34.5 0.9 0.32 10.9 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 KII93465.1 - 4.8e-08 32.6 0.0 0.0019 17.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KII93465.1 - 3.2e-06 27.6 0.2 0.00016 22.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII93465.1 - 3.3e-06 26.5 1.5 0.012 15.1 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KII93465.1 - 4.8e-06 25.6 0.0 0.00059 18.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 KII93465.1 - 7.4e-06 26.0 0.4 0.039 13.9 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KII93465.1 - 3.8e-05 23.2 0.1 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KII93465.1 - 8.9e-05 23.2 0.2 0.27 12.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KII93465.1 - 0.0004 20.0 1.8 0.59 9.8 0.1 2.7 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KII93465.1 - 0.00057 20.1 0.1 0.3 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KII93465.1 - 0.00063 19.8 0.4 0.39 10.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KII93465.1 - 0.0023 17.7 1.6 0.09 12.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 KII93465.1 - 0.0023 16.6 0.2 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_19 PF13245.1 KII93465.1 - 0.0034 17.1 0.0 0.13 12.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KII93465.1 - 0.0045 16.4 0.4 3.9 6.8 0.1 2.9 2 0 0 2 2 2 1 AAA-like domain Miro PF08477.8 KII93465.1 - 0.018 15.5 0.1 4 7.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 KII93465.1 - 0.021 13.9 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KII93465.1 - 0.022 14.6 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KII93465.1 - 0.031 13.9 0.0 0.55 9.8 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 KII93465.1 - 0.044 13.3 0.2 1.5 8.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KII93465.1 - 0.062 12.5 0.6 5.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ResIII PF04851.10 KII93465.1 - 0.066 13.0 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 KII93465.1 - 0.075 12.5 0.4 10 5.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KII93465.1 - 0.075 12.8 0.5 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.9 KII93465.1 - 0.079 12.6 0.3 17 5.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 KII93465.1 - 0.11 11.9 0.2 16 4.9 0.0 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_14 PF13173.1 KII93465.1 - 0.14 12.0 0.1 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KII93465.1 - 0.19 11.9 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KII93465.1 - 0.23 11.1 1.3 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 KII93465.1 - 0.24 11.1 2.3 2.1 8.0 0.1 2.7 3 0 0 3 3 2 0 NTPase AAA_33 PF13671.1 KII93465.1 - 0.24 11.2 0.8 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KII93465.1 - 0.45 9.9 3.8 0.5 9.7 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 KII93465.1 - 0.46 8.9 2.2 6 5.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ABC_membrane PF00664.18 KII93466.1 - 2.1e-49 168.3 25.7 5.6e-24 85.0 2.7 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KII93466.1 - 2.9e-43 147.4 0.0 1.3e-26 93.4 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KII93466.1 - 1.4e-11 44.0 1.8 0.018 14.3 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII93466.1 - 1.6e-08 34.9 0.3 0.29 11.0 0.1 4.1 2 2 1 3 3 3 3 AAA domain AAA_25 PF13481.1 KII93466.1 - 1.9e-08 33.9 0.1 0.001 18.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KII93466.1 - 6.4e-07 29.5 0.8 0.0055 16.7 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KII93466.1 - 1.6e-06 27.5 1.0 0.0087 15.5 0.0 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KII93466.1 - 2.1e-06 26.8 0.0 0.00049 19.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 KII93466.1 - 2.7e-05 24.6 3.2 0.00031 21.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KII93466.1 - 4.6e-05 22.9 1.1 0.31 10.4 0.1 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KII93466.1 - 5.6e-05 23.9 0.1 0.28 12.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KII93466.1 - 0.00025 21.1 0.2 0.32 11.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KII93466.1 - 0.00034 20.9 0.5 0.34 11.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 KII93466.1 - 0.00044 19.9 2.3 0.51 10.0 0.1 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KII93466.1 - 0.0033 17.2 2.3 0.11 12.3 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 KII93466.1 - 0.0042 15.8 0.1 0.021 13.4 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_19 PF13245.1 KII93466.1 - 0.0055 16.4 0.1 0.17 11.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KII93466.1 - 0.0057 16.1 0.6 4.3 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KII93466.1 - 0.0092 15.1 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KII93466.1 - 0.011 16.2 0.1 3.6 8.0 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ResIII PF04851.10 KII93466.1 - 0.011 15.5 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 KII93466.1 - 0.022 14.6 0.4 1.1 9.2 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KII93466.1 - 0.036 13.7 0.0 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 KII93466.1 - 0.04 13.4 0.0 14 5.1 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.1 KII93466.1 - 0.05 13.1 0.2 2 7.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KII93466.1 - 0.057 12.7 0.5 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 KII93466.1 - 0.078 12.5 0.4 9.8 5.6 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 KII93466.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 KII93466.1 - 0.094 12.4 0.3 17 5.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KII93466.1 - 0.12 12.3 0.0 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KII93466.1 - 0.19 11.4 2.2 2.2 7.9 0.1 2.7 3 0 0 3 3 2 0 NTPase Dynamin_N PF00350.18 KII93466.1 - 0.21 11.4 1.8 22 4.8 0.0 3.0 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.7 KII93466.1 - 0.22 11.1 1.6 3.9 7.1 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 KII93466.1 - 0.26 11.1 0.9 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 KII93466.1 - 0.33 9.5 2.1 6.6 5.2 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RseC_MucC PF04246.7 KII93466.1 - 0.42 10.1 2.0 6.6 6.3 0.1 3.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC cobW PF02492.14 KII93466.1 - 0.57 9.6 4.2 0.5 9.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RhoGAP PF00620.22 KII93467.1 - 2.7e-43 147.1 0.2 2.6e-42 143.9 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KII93467.1 - 5.1e-08 32.9 2.7 7.3e-08 32.4 0.7 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PIF1 PF05970.9 KII93468.1 - 3.5e-09 36.0 0.0 4.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KII93468.1 - 0.0062 16.6 0.0 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Diphtheria_T PF02764.9 KII93468.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, T domain EHN PF06441.7 KII93470.1 - 3.3e-31 107.5 0.1 7.1e-31 106.4 0.0 1.6 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KII93470.1 - 1.7e-12 47.6 0.4 2.6e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII93470.1 - 2.2e-06 27.4 0.0 5.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold FAD_binding_6 PF00970.19 KII93471.1 - 1.8e-31 108.1 0.0 2.8e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KII93471.1 - 3.2e-28 98.4 0.0 5.3e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KII93471.1 - 0.00013 21.9 0.0 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KII93471.1 - 0.00096 19.1 0.0 0.002 18.0 0.0 1.5 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DSPc PF00782.15 KII93473.1 - 1.1e-21 76.7 0.0 1.3e-19 70.0 0.0 3.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII93473.1 - 0.0028 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KII93473.1 - 0.07 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF846 PF05832.7 KII93474.1 - 1.6e-52 176.9 8.2 2.1e-52 176.6 5.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3792 PF12670.2 KII93474.1 - 0.058 13.2 0.6 0.058 13.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) MtN3_slv PF03083.11 KII93475.1 - 0.19 11.6 2.6 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ATG16 PF08614.6 KII93476.1 - 0.02 14.7 1.1 0.02 14.7 0.8 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CSTF2_hinge PF14327.1 KII93476.1 - 0.034 14.2 0.1 0.14 12.2 0.0 1.9 1 1 1 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 CENP-B_N PF04218.8 KII93476.1 - 0.054 12.9 0.4 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DivIVA PF05103.8 KII93476.1 - 0.64 10.0 4.1 0.36 10.8 1.5 1.5 1 1 1 2 2 2 0 DivIVA protein RNA_pol_Rpb8 PF03870.10 KII93478.1 - 1.1e-39 135.7 0.1 7.5e-39 133.0 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb8 Sec7 PF01369.15 KII93480.1 - 4.8e-28 98.1 0.0 7.2e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KII93480.1 - 4.9e-12 46.0 0.0 8.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KII93480.1 - 8.5e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PH domain MscS_porin PF12795.2 KII93480.1 - 0.16 11.2 1.6 0.28 10.4 1.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Pescadillo_N PF06732.6 KII93481.1 - 5.1e-116 386.8 1.7 9.8e-116 385.9 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KII93481.1 - 2.9e-10 40.1 0.0 5.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LSM PF01423.17 KII93482.1 - 1.6e-17 62.7 0.2 2.1e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain RdRP PF05183.7 KII93483.1 - 9e-156 519.9 0.0 1.3e-155 519.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Complex1_LYR PF05347.10 KII93484.1 - 5.5e-16 58.1 0.8 7.3e-16 57.7 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII93484.1 - 4.2e-14 52.4 0.4 5e-14 52.2 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Siva PF05458.7 KII93486.1 - 1 8.9 6.2 0.33 10.5 2.7 1.4 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Cyclin_N PF00134.18 KII93487.1 - 1.2e-37 128.3 1.4 2.4e-37 127.3 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KII93487.1 - 5.1e-08 32.8 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.17 KII93488.1 - 8.5e-11 42.4 0.3 4.3e-10 40.1 0.2 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII93488.1 - 0.0035 17.1 0.1 0.037 13.8 0.1 2.3 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain JSRP PF15312.1 KII93489.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Lyase_8 PF02278.13 KII93490.1 - 6.1e-34 117.6 0.0 1.3e-33 116.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KII93490.1 - 7.8e-23 80.8 0.3 1.2e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 KII93490.1 - 4.5e-06 26.5 1.3 2.1e-05 24.4 0.9 2.1 1 1 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain plasmid_Toxin PF12703.2 KII93490.1 - 0.084 12.7 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system CAP PF00188.21 KII93492.1 - 7.5e-21 74.9 1.2 7.5e-21 74.9 0.8 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF605 PF04652.11 KII93492.1 - 0.49 9.7 32.3 0.78 9.0 22.4 1.2 1 0 0 1 1 1 0 Vta1 like CAP PF00188.21 KII93493.1 - 3.3e-24 85.7 1.2 4e-24 85.4 0.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2012 PF09430.5 KII93494.1 - 4.3e-23 81.4 0.0 7.2e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KII93494.1 - 0.023 14.7 0.1 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain fn3_3 PF14686.1 KII93494.1 - 0.033 14.3 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Fcf1 PF04900.7 KII93495.1 - 5e-29 100.3 0.3 1.1e-28 99.3 0.2 1.5 1 0 0 1 1 1 1 Fcf1 PP28 PF10252.4 KII93495.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.1 4 0 0 4 4 4 0 Casein kinase substrate phosphoprotein PP28 WAC_Acf1_DNA_bd PF10537.4 KII93497.1 - 4e-33 113.6 1.0 1.1e-32 112.2 0.7 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KII93497.1 - 4.8e-12 45.4 0.1 1.5e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KII93497.1 - 9.6e-06 25.3 1.0 0.00038 20.2 0.0 2.6 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KII93497.1 - 0.00029 20.5 0.1 0.00069 19.3 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KII93497.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Nop53 PF07767.6 KII93497.1 - 2.4 7.0 40.0 0.11 11.4 10.5 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Aa_trans PF01490.13 KII93498.1 - 4.1e-55 186.9 16.5 4.5e-55 186.7 11.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KII93498.1 - 9.1e-05 21.4 9.8 9.1e-05 21.4 6.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family PCI_Csn8 PF10075.4 KII93499.1 - 1.7e-21 76.4 0.0 3.3e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KII93499.1 - 6.7e-20 71.5 0.1 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WD40 PF00400.27 KII93500.1 - 3.5e-75 245.4 19.4 9e-14 50.7 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KII93500.1 - 2e-12 47.2 0.0 1.3e-05 25.0 0.0 3.7 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KII93500.1 - 5.6e-08 31.3 7.8 0.0017 16.5 0.2 4.5 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KII93500.1 - 9.2e-05 20.8 0.5 0.7 8.1 0.0 3.3 1 1 3 4 4 4 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KII93500.1 - 0.00048 19.0 0.2 0.1 11.3 0.0 2.9 1 1 2 3 3 3 1 Coatomer WD associated region Nucleoporin_N PF08801.6 KII93500.1 - 0.00092 18.0 2.9 1.4 7.5 0.1 3.8 1 1 3 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.1 KII93500.1 - 0.0082 15.2 0.6 6.2 5.8 0.0 3.6 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 KII93500.1 - 0.0087 14.9 0.2 0.74 8.6 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) IKI3 PF04762.7 KII93500.1 - 0.013 13.3 0.3 0.11 10.3 0.0 2.3 2 1 1 3 3 3 0 IKI3 family Hira PF07569.6 KII93500.1 - 0.17 11.0 0.5 22 4.1 0.0 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split ubiquitin PF00240.18 KII93501.1 - 2.3e-137 446.5 21.2 6.5e-34 115.1 0.5 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 KII93501.1 - 1.6e-77 255.1 20.9 7.2e-19 67.2 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KII93501.1 - 4.4e-24 84.5 9.7 0.00019 21.6 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KII93501.1 - 5.4e-21 74.9 0.6 0.0017 18.0 0.0 4.1 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KII93501.1 - 8.3e-14 51.4 3.0 0.14 12.0 0.0 4.9 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KII93501.1 - 2.2e-13 50.2 2.4 0.16 12.1 0.0 4.4 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KII93501.1 - 2.4e-10 40.3 0.0 1.8 8.6 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 KII93501.1 - 2.7e-07 30.2 4.5 4.1 7.2 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 KII93501.1 - 1.6e-06 27.4 0.6 1.3 8.1 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 KII93501.1 - 6.3e-06 26.0 4.8 7.8 6.4 0.0 4.3 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 KII93501.1 - 0.001 19.3 0.7 78 3.7 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 KII93501.1 - 0.0016 17.8 0.1 9.3 5.6 0.0 3.9 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 KII93501.1 - 0.0025 16.1 12.5 4.8 5.3 0.2 5.5 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Brix PF04427.13 KII93501.1 - 0.028 14.0 0.2 33 4.0 0.0 3.7 1 1 1 4 4 4 0 Brix domain Tash_PEST PF07708.6 KII93501.1 - 0.047 13.6 29.1 4 7.4 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 KII93501.1 - 0.099 12.6 7.0 65 3.6 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 KII93501.1 - 1.9 8.6 11.7 1e+02 3.0 0.1 5.7 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 KII93501.1 - 4 7.4 7.0 2e+02 2.0 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 KII93501.1 - 4.6 6.9 13.8 51 3.6 0.1 4.2 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Ribosomal_S3_C PF00189.15 KII93502.1 - 3.7e-17 62.3 0.0 7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KII93502.1 - 3.8e-12 45.5 0.0 6.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KII93502.1 - 0.045 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mucin PF01456.12 KII93503.1 - 0.0012 18.6 37.4 0.0016 18.2 25.9 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Herpes_TAF50 PF03326.8 KII93503.1 - 0.31 9.9 14.4 0.36 9.7 10.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) SoxE PF06525.6 KII93503.1 - 0.71 9.1 8.8 1.1 8.4 6.1 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) TFIIA PF03153.8 KII93503.1 - 1.4 8.7 4.5 1.6 8.5 3.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM154 PF15102.1 KII93503.1 - 2.2 7.9 13.7 3.4 7.3 9.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family Med3 PF11593.3 KII93503.1 - 2.5 7.2 15.5 2.6 7.2 10.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AJAP1_PANP_C PF15298.1 KII93503.1 - 3.1 7.6 24.1 4.7 7.0 16.7 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DNA_pol_viral_N PF00242.12 KII93503.1 - 5.1 6.0 7.3 6.6 5.6 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Amidase PF01425.16 KII93504.1 - 4.8e-103 345.3 0.0 5.6e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Thiolase_N PF00108.18 KII93505.1 - 2e-68 230.2 0.0 3.5e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KII93505.1 - 4.1e-40 136.0 0.0 1.4e-39 134.3 0.0 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KII93505.1 - 0.0046 16.4 0.5 0.013 14.9 0.1 1.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KII93505.1 - 0.021 14.5 0.3 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.7 KII93505.1 - 0.14 11.2 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein Ribosomal_L32p PF01783.18 KII93506.1 - 7.9e-16 57.9 4.5 1.2e-15 57.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.1 KII93506.1 - 0.0022 17.7 1.9 0.0043 16.7 1.3 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-UBR PF02207.15 KII93506.1 - 0.015 14.9 0.3 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.2 KII93506.1 - 0.035 13.9 1.3 0.05 13.4 0.9 1.2 1 0 0 1 1 1 0 Double zinc ribbon Stc1 PF12898.2 KII93506.1 - 0.053 13.5 1.7 0.082 12.9 1.2 1.3 1 0 0 1 1 1 0 Stc1 domain DUF1352 PF07086.7 KII93506.1 - 0.085 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) zf-ribbon_3 PF13248.1 KII93506.1 - 0.74 9.1 3.9 1.2 8.4 2.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain ETC_C1_NDUFA5 PF04716.9 KII93507.1 - 1.3e-18 66.2 0.0 2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RPE65 PF03055.10 KII93508.1 - 9.4e-99 331.1 0.0 1.1e-98 330.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GTP_EFTU PF00009.22 KII93509.1 - 7.5e-56 188.5 0.1 1.2e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KII93509.1 - 4.7e-37 126.1 0.0 1.1e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KII93509.1 - 7.7e-16 57.9 1.1 7.7e-16 57.9 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KII93509.1 - 0.00045 19.8 0.5 0.0016 18.0 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KII93509.1 - 0.0027 17.6 0.4 0.0083 16.0 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 KII93509.1 - 0.038 13.8 0.2 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Pkinase PF00069.20 KII93510.1 - 2.2e-42 145.0 0.0 9e-40 136.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93510.1 - 2.1e-14 53.2 0.0 8.3e-13 48.0 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93510.1 - 0.00046 19.2 0.0 0.00095 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII93510.1 - 0.0021 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII93510.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.17 KII93511.1 - 5.4e-17 61.0 0.1 7.2e-17 60.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain PHD PF00628.24 KII93512.1 - 5.3e-10 38.8 7.6 5.3e-10 38.8 5.2 2.4 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 KII93512.1 - 0.0004 19.9 1.1 0.0004 19.9 0.8 2.5 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain HABP4_PAI-RBP1 PF04774.10 KII93514.1 - 0.0012 19.2 10.9 0.0012 19.2 7.6 3.4 3 2 0 3 3 3 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.17 KII93515.1 - 3.1e-25 89.1 0.0 4e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.12 KII93516.1 - 4.1e-65 219.3 0.0 5e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.13 KII93517.1 - 7.8e-48 161.1 3.3 9.1e-48 160.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 AGT PF11440.3 KII93517.1 - 0.047 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Acetyltransf_10 PF13673.1 KII93518.1 - 7.2e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII93518.1 - 0.00051 20.1 0.0 0.0013 18.8 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KII93518.1 - 0.046 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DLH PF01738.13 KII93519.1 - 5.3e-23 81.4 0.0 6.2e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KII93519.1 - 1.8e-06 27.7 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KII93519.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2048 PF09752.4 KII93519.1 - 0.13 11.1 0.0 0.33 9.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) MFS_1 PF07690.11 KII93520.1 - 1.3e-43 149.1 35.6 1.3e-43 149.1 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KII93520.1 - 0.02 13.0 4.8 0.035 12.2 3.3 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.11 KII93524.1 - 1.8e-33 115.7 33.1 1.8e-33 115.7 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII93524.1 - 4.2e-11 42.0 30.7 5.7e-11 41.6 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Elong_Iki1 PF10483.4 KII93526.1 - 6.9e-08 32.1 0.0 7.5e-07 28.7 0.0 2.4 1 1 0 1 1 1 1 Elongator subunit Iki1 SLX9 PF15341.1 KII93528.1 - 1.3e-25 90.1 3.7 1.8e-25 89.7 2.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HisKA_3 PF07730.8 KII93529.1 - 0.064 13.6 3.8 0.3 11.4 0.1 2.3 1 1 1 2 2 2 0 Histidine kinase APG6 PF04111.7 KII93529.1 - 0.22 10.5 9.4 0.26 10.3 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin-relat_1 PF12711.2 KII93529.1 - 1.1 9.6 11.7 0.31 11.4 2.7 2.5 1 1 0 2 2 2 0 Kinesin motor DUF724 PF05266.9 KII93529.1 - 1.8 8.1 7.8 2.4 7.7 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) zf-C4H2 PF10146.4 KII93529.1 - 6.5 6.7 9.6 8.8 6.2 6.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein XhlA PF10779.4 KII93529.1 - 9.9 6.1 9.6 3.2e+02 1.3 6.7 2.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF4164 PF13747.1 KII93531.1 - 0.0072 16.4 3.7 0.0072 16.4 2.5 3.5 2 2 1 3 3 3 1 Domain of unknown function (DUF4164) DUF2540 PF10802.3 KII93531.1 - 0.074 12.7 0.2 0.22 11.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) 2-oxoacid_dh PF00198.18 KII93532.1 - 2.4e-80 269.1 0.0 3.2e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KII93532.1 - 8.1e-19 67.0 2.2 1.7e-18 66.0 0.8 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KII93532.1 - 2e-15 56.1 0.3 5.5e-15 54.7 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KII93532.1 - 0.087 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like QRPTase_N PF02749.11 KII93532.1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain EXOSC1 PF10447.4 KII93533.1 - 2.5e-20 72.2 0.0 4.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KII93533.1 - 0.0011 18.2 1.0 0.008 15.4 0.7 2.3 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region NUDE_C PF04880.8 KII93534.1 - 8e-11 42.5 3.0 8e-11 42.5 2.1 5.9 2 2 4 7 7 7 1 NUDE protein, C-terminal conserved region DUF3523 PF12037.3 KII93534.1 - 0.07 12.0 19.7 0.11 11.4 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF3138 PF11336.3 KII93534.1 - 0.42 8.7 2.3 3.2 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) ERM PF00769.14 KII93534.1 - 1.4 8.3 28.9 0.33 10.4 7.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 KII93534.1 - 1.7 8.1 30.3 0.23 11.0 10.3 2.4 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 KII93534.1 - 2.1 8.2 31.2 0.55 10.0 16.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 KII93534.1 - 2.7 7.9 5.9 1.5 8.6 0.6 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 KII93534.1 - 4.7 6.2 7.2 7.9 5.4 5.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF3287 PF11690.3 KII93534.1 - 5.8 7.0 12.0 9.3 6.3 4.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) ADIP PF11559.3 KII93534.1 - 9.8 6.0 27.2 0.3 10.9 4.6 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NUDIX PF00293.23 KII93535.1 - 1.5e-12 47.3 0.2 3.1e-12 46.3 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain Es2 PF09751.4 KII93536.1 - 2e-70 238.2 0.0 2.8e-68 231.2 0.0 2.1 1 1 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.4 KII93537.1 - 3.8e-26 91.2 11.5 3.8e-26 91.2 7.9 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 KII93537.1 - 1.7 7.8 15.2 2.4 7.2 10.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) EamA PF00892.15 KII93539.1 - 3e-07 30.5 29.1 2e-06 27.8 1.7 2.8 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KII93539.1 - 0.0054 16.9 3.5 0.0054 16.9 2.5 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 KII93539.1 - 0.018 13.8 9.5 0.25 10.1 0.5 3.5 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KII93539.1 - 1.8 8.2 22.3 0.069 12.8 0.9 2.5 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF4131 PF13567.1 KII93539.1 - 2 7.8 9.5 0.75 9.1 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) APG6 PF04111.7 KII93540.1 - 5.2 6.0 28.4 2.2 7.2 1.6 2.8 1 1 0 2 2 2 0 Autophagy protein Apg6 Rad51 PF08423.6 KII93541.1 - 3.3e-07 29.4 0.0 7.7e-07 28.2 0.0 1.5 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KII93541.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KII93541.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC RecA PF00154.16 KII93541.1 - 0.03 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_14 PF13173.1 KII93541.1 - 0.044 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KII93541.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 KII93541.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_35 PF14516.1 KII93541.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AMP-binding PF00501.23 KII93542.1 - 2.7e-25 88.6 0.1 3e-24 85.1 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme 53-BP1_Tudor PF09038.5 KII93542.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor PPR_2 PF13041.1 KII93544.1 - 1.4e-28 98.5 0.0 2.4e-06 27.4 0.0 6.1 6 0 0 6 6 6 5 PPR repeat family PPR_3 PF13812.1 KII93544.1 - 1.7e-19 68.4 13.1 0.00038 20.5 0.0 10.5 10 1 1 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.15 KII93544.1 - 2.6e-11 42.6 0.1 0.026 14.4 0.0 6.2 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 KII93544.1 - 1.8e-08 33.6 0.0 0.14 11.6 0.0 5.7 6 0 0 6 6 6 2 PPR repeat Hap4_Hap_bind PF10297.4 KII93545.1 - 7.1e-09 35.2 3.5 1.6e-08 34.0 2.4 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KII93545.1 - 5.4e-07 29.4 14.3 0.00018 21.4 2.2 2.4 2 0 0 2 2 2 2 bZIP transcription factor HAP1_N PF04849.8 KII93545.1 - 0.026 13.4 4.9 0.045 12.6 3.4 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_2 PF07716.10 KII93545.1 - 0.032 14.0 16.4 2 8.2 2.8 2.6 1 1 1 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 KII93545.1 - 0.037 14.3 2.2 0.078 13.3 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 KII93545.1 - 0.042 13.5 2.7 0.072 12.8 1.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Seadorna_VP6 PF07407.6 KII93545.1 - 0.17 10.6 0.5 0.24 10.1 0.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF2205 PF10224.4 KII93545.1 - 0.32 10.6 5.7 0.71 9.4 3.9 1.6 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 KII93545.1 - 0.44 10.8 10.4 0.91 9.8 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) eIF2A PF08662.6 KII93546.1 - 3.7e-43 147.5 2.7 8.1e-39 133.3 0.1 5.0 3 3 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KII93546.1 - 6.8e-08 32.0 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII93546.1 - 1.4e-06 28.1 0.0 3.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KII93546.1 - 2.8e-05 23.8 0.8 1.2 9.1 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat RRM_5 PF13893.1 KII93546.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KII93547.1 - 1.6e-41 142.3 26.3 4.2e-41 140.9 18.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII93547.1 - 3.9e-17 61.9 36.3 2.6e-09 36.2 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SLS PF14611.1 KII93548.1 - 6.6e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.7 KII93549.1 - 2.5e-67 226.5 27.2 2.5e-67 226.5 18.9 3.2 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 KII93549.1 - 2.5e-52 177.4 0.1 7.1e-52 176.0 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KII93549.1 - 1.5e-44 151.3 6.9 1.5e-44 151.3 4.8 5.5 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) UPF0181 PF03701.9 KII93549.1 - 0.03 13.6 1.7 0.14 11.4 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) DUF423 PF04241.10 KII93550.1 - 4e-21 74.7 3.3 5.1e-21 74.4 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ras PF00071.17 KII93552.1 - 1.2e-53 180.7 0.0 1.4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII93552.1 - 2.4e-17 63.5 0.0 3.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII93552.1 - 5.8e-06 25.6 0.0 8.3e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Requiem_N PF14051.1 KII93553.1 - 0.00073 19.4 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. DUF1180 PF06679.7 KII93553.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) Zn_clus PF00172.13 KII93554.1 - 1e-07 31.7 10.2 2.2e-07 30.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII93554.1 - 5.6e-07 28.6 0.2 2.7e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Prefoldin_2 PF01920.15 KII93554.1 - 0.09 12.5 0.1 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit PDT PF00800.13 KII93555.1 - 1.7e-53 180.8 0.0 2.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase zf-CCCH PF00642.19 KII93556.1 - 2.7e-19 68.3 24.8 4.6e-05 22.9 0.4 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KII93556.1 - 2.2e-05 24.1 3.7 0.0001 22.0 2.6 2.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KII93556.1 - 0.013 15.2 0.1 0.038 13.7 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII93556.1 - 0.026 14.1 1.9 0.071 12.7 1.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_2 PF14608.1 KII93556.1 - 0.08 12.9 0.6 0.08 12.9 0.4 5.6 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type UPF0047 PF01894.12 KII93557.1 - 3.8e-40 136.3 0.1 4.3e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.13 KII93558.1 - 1e-07 31.1 0.0 1.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3112 PF11309.3 KII93558.1 - 0.075 12.8 0.1 7.7 6.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) DUF3563 PF12086.3 KII93558.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) RhoGEF PF00621.15 KII93560.1 - 8.5e-17 61.6 0.0 1.3e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Exo_endo_phos PF03372.18 KII93561.1 - 9.1e-20 71.6 0.0 1.2e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.16 KII93562.1 - 4.2e-19 68.9 0.0 1.3e-09 37.9 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KII93562.1 - 1.3e-08 34.7 0.0 6.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF4212 PF13937.1 KII93563.1 - 0.04 13.9 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) NUFIP1 PF10453.4 KII93564.1 - 1.5e-16 59.5 0.7 2.6e-16 58.8 0.5 1.3 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.7 KII93564.1 - 0.019 14.8 0.3 0.035 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) KH_1 PF00013.24 KII93565.1 - 9.6e-40 134.0 11.7 7.7e-16 57.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KII93565.1 - 1.4e-27 94.8 12.8 8.3e-10 38.0 1.1 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KII93565.1 - 2.5e-11 43.0 0.6 0.0026 17.3 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KII93565.1 - 4.4e-09 35.7 7.7 0.025 14.1 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 KII93565.1 - 0.00012 21.7 2.7 0.24 11.1 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KII93565.1 - 0.084 12.3 0.3 5.8 6.3 0.0 2.6 3 0 0 3 3 3 0 dUTPase Ribosomal_L13 PF00572.13 KII93566.1 - 1.7e-26 92.7 0.0 2.5e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 SGL PF08450.7 KII93567.1 - 6.8e-66 222.1 0.0 9.7e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KII93567.1 - 0.0028 17.6 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Arylesterase YmzC PF14157.1 KII93567.1 - 0.098 12.4 0.0 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 YmzC-like protein PP-binding PF00550.20 KII93568.1 - 1.7e-12 47.3 0.3 2.4e-12 46.9 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KII93568.1 - 5e-06 26.4 0.2 6.2e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L17 PF01196.14 KII93569.1 - 3.7e-36 123.5 0.1 7.4e-36 122.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 AIB PF15334.1 KII93569.1 - 0.049 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein ADH_N PF08240.7 KII93570.1 - 1.4e-29 102.0 1.6 1.4e-29 102.0 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII93570.1 - 8.6e-12 44.7 0.0 6e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KII93570.1 - 0.00061 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain QRPTase_C PF01729.14 KII93570.1 - 0.0017 17.8 0.0 0.005 16.3 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain 2-Hacid_dh_C PF02826.14 KII93570.1 - 0.0034 16.5 0.1 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KII93570.1 - 0.0075 16.8 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain mono-CXXC PF15626.1 KII93570.1 - 0.4 10.6 3.3 12 5.9 0.0 2.3 2 0 0 2 2 2 0 single CXXC unit DUF898 PF05987.8 KII93572.1 - 0.013 14.4 7.3 0.017 14.0 5.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Zip PF02535.17 KII93572.1 - 0.033 13.2 0.0 0.06 12.3 0.0 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter gpUL132 PF11359.3 KII93572.1 - 0.14 11.5 4.2 4.3 6.5 0.1 2.2 1 1 1 2 2 2 0 Glycoprotein UL132 Tetraspannin PF00335.15 KII93572.1 - 0.97 8.6 11.4 5.7 6.1 8.2 2.1 1 1 0 1 1 1 0 Tetraspanin family E1_DerP2_DerF2 PF02221.10 KII93573.1 - 4.5e-24 85.2 0.5 5.4e-24 84.9 0.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KII93573.1 - 0.00012 22.1 0.2 0.00021 21.3 0.1 1.5 1 1 0 1 1 1 1 ML-like domain YbbR PF07949.7 KII93573.1 - 0.15 12.1 1.1 0.51 10.4 0.1 2.2 2 1 0 2 2 2 0 YbbR-like protein DUF3318 PF11780.3 KII93574.1 - 0.043 13.3 0.1 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Pex14_N PF04695.8 KII93575.1 - 3.8e-26 91.7 9.2 4.8e-26 91.4 1.7 3.2 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.7 KII93575.1 - 0.00078 19.2 1.2 0.0022 17.7 0.7 1.9 2 1 0 2 2 1 1 Protein of unknown function (DUF1664) DUF3584 PF12128.3 KII93575.1 - 0.00082 16.8 9.6 0.0011 16.4 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Laminin_II PF06009.7 KII93575.1 - 0.0067 16.1 8.6 0.012 15.4 6.0 1.3 1 0 0 1 1 1 1 Laminin Domain II AAA_13 PF13166.1 KII93575.1 - 0.011 14.2 6.7 0.014 13.8 4.6 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KII93575.1 - 0.017 14.6 8.4 0.028 14.0 5.8 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KII93575.1 - 0.024 12.5 0.0 0.025 12.4 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EzrA PF06160.7 KII93575.1 - 0.029 12.5 6.0 0.053 11.7 4.2 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1759 PF03564.10 KII93575.1 - 0.029 14.1 2.0 0.058 13.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Med9 PF07544.8 KII93575.1 - 0.041 13.6 1.2 0.041 13.6 0.9 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mt_ATP-synt_D PF05873.7 KII93575.1 - 0.051 13.2 3.4 0.11 12.1 2.4 1.4 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Baculo_PEP_C PF04513.7 KII93575.1 - 0.059 13.1 2.5 0.19 11.5 1.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.3 KII93575.1 - 0.066 12.4 6.5 0.1 11.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ING PF12998.2 KII93575.1 - 0.08 13.2 6.0 0.099 12.9 3.1 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Spc7 PF08317.6 KII93575.1 - 0.087 11.4 5.7 0.18 10.4 3.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KII93575.1 - 0.1 12.8 10.3 8.1 6.7 5.5 3.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Hemerythrin PF01814.18 KII93575.1 - 0.11 12.7 5.0 0.19 11.9 3.4 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain IFT57 PF10498.4 KII93575.1 - 0.11 11.2 7.7 0.32 9.6 5.3 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2317 PF10079.4 KII93575.1 - 0.11 11.0 6.9 0.16 10.5 4.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Prominin PF05478.6 KII93575.1 - 0.18 9.3 1.6 0.23 8.9 1.1 1.1 1 0 0 1 1 1 0 Prominin FliJ PF02050.11 KII93575.1 - 0.18 11.8 7.6 0.14 12.2 0.5 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein COG2 PF06148.6 KII93575.1 - 0.24 11.2 10.9 0.46 10.3 1.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ferritin PF00210.19 KII93575.1 - 0.25 11.0 4.3 0.31 10.7 2.4 1.6 2 0 0 2 2 1 0 Ferritin-like domain DUF342 PF03961.8 KII93575.1 - 0.28 9.5 5.2 0.68 8.2 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KII93575.1 - 0.29 11.2 4.3 0.5 10.4 3.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2959 PF11172.3 KII93575.1 - 0.31 10.7 5.5 3.6 7.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) FlgN PF05130.7 KII93575.1 - 0.44 10.7 10.8 0.9 9.7 7.5 1.4 1 0 0 1 1 1 0 FlgN protein MscS_porin PF12795.2 KII93575.1 - 0.45 9.7 12.4 1.1 8.4 2.3 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4071 PF13281.1 KII93575.1 - 0.5 9.1 3.6 0.94 8.2 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) APG6 PF04111.7 KII93575.1 - 0.66 8.9 12.3 0.92 8.4 8.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 KII93575.1 - 0.68 8.2 2.1 0.93 7.8 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2458 PF10454.4 KII93575.1 - 0.78 9.6 7.5 2.7 7.8 5.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Tektin PF03148.9 KII93575.1 - 0.8 8.1 12.2 1.7 7.0 8.5 1.5 1 1 0 1 1 1 0 Tektin family MAD PF05557.8 KII93575.1 - 0.85 7.6 11.7 1.1 7.2 8.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cast PF10174.4 KII93575.1 - 0.87 7.5 15.1 3.7 5.4 10.5 1.7 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Mnd1 PF03962.10 KII93575.1 - 0.94 9.1 10.1 1.4 8.5 7.0 1.3 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 KII93575.1 - 1.1 8.1 5.3 1.6 7.6 3.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sas10_Utp3 PF04000.10 KII93575.1 - 1.2 9.3 4.3 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Phage_GPO PF05929.6 KII93575.1 - 1.4 8.1 7.0 2 7.5 4.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1409 PF07197.7 KII93575.1 - 1.7 8.7 5.8 0.27 11.3 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) Fzo_mitofusin PF04799.8 KII93575.1 - 4.4 6.6 6.4 2.8 7.2 1.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF2203 PF09969.4 KII93575.1 - 6.2 7.0 7.5 22 5.2 5.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2664 PF10867.3 KII93575.1 - 6.3 7.4 8.6 2.8 8.6 2.9 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2664) DUF4140 PF13600.1 KII93575.1 - 6.5 7.2 10.3 1.5 9.3 0.2 3.1 1 1 1 2 2 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 KII93575.1 - 7.4 5.4 10.2 12 4.7 7.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) THOC7 PF05615.8 KII93575.1 - 8.9 6.5 13.9 0.96 9.7 3.8 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 GTP_EFTU PF00009.22 KII93576.1 - 1.3e-58 197.5 0.4 1.9e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KII93576.1 - 2.8e-28 97.9 0.3 1.6e-27 95.5 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KII93576.1 - 1.7e-15 56.9 3.9 2.6e-15 56.3 2.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII93576.1 - 4.4e-05 23.4 0.1 7.8e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KII93576.1 - 0.0013 19.1 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KII93576.1 - 0.015 14.7 0.2 7.3 6.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KII93576.1 - 0.025 14.0 0.5 0.047 13.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.1 KII93576.1 - 0.027 14.1 0.2 0.076 12.6 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DisA_N PF02457.11 KII93576.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding CbiA PF01656.18 KII93576.1 - 0.24 10.7 1.2 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FMN_bind_2 PF04299.7 KII93577.1 - 2.3e-53 180.1 0.0 2.8e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain XPC-binding PF09280.6 KII93577.1 - 0.11 12.0 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 XPC-binding domain GCV_H PF01597.14 KII93578.1 - 2.7e-38 130.3 0.0 3.5e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KII93578.1 - 0.0048 16.4 0.4 0.0098 15.5 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 KII93578.1 - 0.0048 16.5 0.1 0.0097 15.6 0.1 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Tcell_CD4_Cterm PF12104.3 KII93578.1 - 0.06 12.9 1.1 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region ESSS PF10183.4 KII93579.1 - 9.9e-27 93.4 0.3 1.3e-26 93.0 0.2 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RIO1 PF01163.17 KII93580.1 - 3.4e-42 143.9 0.1 8.3e-30 103.5 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KII93580.1 - 1.9e-33 114.3 0.1 3.3e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KII93580.1 - 1.1e-07 31.7 0.7 0.00015 21.5 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KII93580.1 - 1.3e-05 24.3 0.0 0.00012 21.2 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 KII93580.1 - 0.083 10.8 9.4 0.11 10.4 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.10 KII93580.1 - 0.88 8.7 7.7 1.5 8.0 5.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.9 KII93580.1 - 2.4 6.0 6.9 3.3 5.6 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4278 PF14105.1 KII93581.1 - 7.5e-07 28.9 0.3 0.04 13.8 0.1 3.7 1 1 3 4 4 4 4 Domain of unknown function (DUF4278) Polyketide_cyc2 PF10604.4 KII93581.1 - 0.0029 17.7 0.1 0.0029 17.7 0.1 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_23 PF13489.1 KII93582.1 - 3e-05 23.7 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII93582.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII93582.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.19 KII93583.1 - 3.7e-17 62.1 0.1 6.1e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII93583.1 - 4.9e-11 42.6 0.0 7.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII93583.1 - 1.3e-09 38.1 0.1 2.1e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII93583.1 - 5.9e-08 32.3 0.0 1.2e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KII93583.1 - 4e-07 30.1 0.0 6.2e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII93583.1 - 0.0008 19.5 0.1 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII93583.1 - 0.01 15.7 0.1 0.016 15.0 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Sina PF03145.11 KII93583.1 - 0.043 13.4 0.0 0.055 13.1 0.0 1.3 1 1 0 1 1 1 0 Seven in absentia protein family Mito_carr PF00153.22 KII93584.1 - 1.2e-56 188.4 1.7 7e-20 70.5 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 KII93585.1 - 3.4e-15 55.8 0.0 5.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KII93585.1 - 1.7e-08 33.9 0.4 4.8e-08 32.5 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Pyrophosphatase PF00719.14 KII93586.1 - 7.8e-55 184.6 0.1 1e-54 184.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase CFEM PF05730.6 KII93587.1 - 0.017 14.9 7.3 0.036 13.8 5.1 1.6 1 1 0 1 1 1 0 CFEM domain TIL PF01826.12 KII93587.1 - 0.028 14.5 3.8 0.052 13.6 2.6 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF92 PF01940.11 KII93589.1 - 0.17 11.0 0.9 0.24 10.5 0.6 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF3337 PF11816.3 KII93590.1 - 0.02 14.3 1.6 0.024 14.0 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Dehalogenase PF13486.1 KII93590.1 - 0.074 12.4 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Lin-8 PF03353.10 KII93590.1 - 0.11 11.7 4.4 0.15 11.3 3.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SnAC PF14619.1 KII93590.1 - 0.14 12.3 5.2 0.32 11.2 3.6 1.7 1 1 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DUF566 PF04484.7 KII93590.1 - 0.54 9.7 10.1 0.71 9.3 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) RAP1 PF07218.6 KII93590.1 - 0.72 7.8 3.1 0.88 7.5 2.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Histone PF00125.19 KII93593.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII93593.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KII93593.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KII93593.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KII93593.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KII93593.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.15 KII93594.1 - 3.9e-27 93.9 0.1 5.1e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KII93594.1 - 1.7e-06 28.0 0.0 0.00016 21.7 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KII93594.1 - 3.9e-06 27.0 0.1 4.6e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KII93594.1 - 0.0015 18.4 0.1 0.0033 17.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KII93594.1 - 0.0021 17.7 0.1 0.0056 16.3 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KII93594.1 - 0.0032 17.0 0.0 0.0042 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF2847 PF11009.3 KII93594.1 - 0.011 15.3 0.0 0.046 13.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2847) Redoxin PF08534.5 KII93594.1 - 0.024 14.2 0.1 0.062 12.8 0.1 1.5 1 1 0 1 1 1 0 Redoxin TrbC_Ftype PF09673.5 KII93594.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein dsrm PF00035.20 KII93595.1 - 1.8e-10 41.2 0.1 4.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KII93595.1 - 6.8e-06 26.0 0.0 9.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KII93595.1 - 0.00017 22.0 0.0 0.00035 20.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Sporozoite_P67 PF05642.6 KII93596.1 - 0.02 12.7 0.4 0.029 12.2 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2771 PF10969.3 KII93596.1 - 0.088 12.0 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) Chorion_2 PF03964.10 KII93597.1 - 0.039 14.5 3.3 0.068 13.7 2.3 1.4 1 0 0 1 1 1 0 Chorion family 2 Glyco_transf_22 PF03901.12 KII93600.1 - 9.6e-84 281.7 7.4 2.2e-83 280.5 5.1 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamin_N PF00350.18 KII93601.1 - 3.3e-17 62.8 0.1 1.4e-16 60.7 0.0 2.1 2 0 0 2 2 1 1 Dynamin family MMR_HSR1 PF01926.18 KII93601.1 - 4.3e-09 36.3 0.1 0.00026 20.9 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase ABC_tran PF00005.22 KII93601.1 - 1.2e-05 25.6 0.1 0.0004 20.6 0.0 3.0 3 0 0 3 3 3 1 ABC transporter FtsK_SpoIIIE PF01580.13 KII93601.1 - 0.00014 21.3 0.1 0.00053 19.5 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KII93601.1 - 0.00037 21.3 0.0 0.0018 19.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KII93601.1 - 0.00093 18.6 0.0 0.0024 17.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.11 KII93601.1 - 0.0013 17.8 0.0 0.0031 16.6 0.0 1.7 1 0 0 1 1 1 1 AIG1 family AAA_23 PF13476.1 KII93601.1 - 0.0015 18.8 2.9 0.12 12.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KII93601.1 - 0.0031 16.8 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF87 PF01935.12 KII93601.1 - 0.0051 16.6 0.0 0.0051 16.6 0.0 2.9 4 1 0 4 4 4 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KII93601.1 - 0.009 16.1 0.4 0.69 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 KII93601.1 - 0.02 13.7 0.0 0.091 11.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 KII93601.1 - 0.026 13.9 0.3 0.13 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.22 KII93601.1 - 0.029 13.8 0.3 8.5 5.7 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KII93601.1 - 0.049 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF718 PF05336.8 KII93601.1 - 0.069 12.9 0.4 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF718) FliE PF02049.13 KII93601.1 - 0.24 11.4 3.9 0.93 9.5 0.0 3.4 3 1 0 3 3 3 0 Flagellar hook-basal body complex protein FliE F-box-like PF12937.2 KII93602.1 - 1.7e-10 40.4 0.2 3.7e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII93602.1 - 4.8e-08 32.4 0.1 9.4e-08 31.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 KII93602.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 PRANC domain CutC PF03932.9 KII93603.1 - 8.9e-57 191.6 0.2 1.1e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 CutC family FA_desaturase PF00487.19 KII93604.1 - 6.6e-08 32.2 3.7 6.6e-08 32.2 2.6 2.7 3 0 0 3 3 3 2 Fatty acid desaturase Cyt-b5 PF00173.23 KII93604.1 - 0.00012 21.8 0.0 0.00034 20.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Bromodomain PF00439.20 KII93605.1 - 5.6e-37 125.5 4.5 4.2e-19 68.2 0.5 2.3 2 0 0 2 2 2 2 Bromodomain API5 PF05918.6 KII93605.1 - 3 6.2 5.6 6.4 5.1 3.9 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-DHHC PF01529.15 KII93606.1 - 5.5e-43 146.3 2.6 5.5e-43 146.3 1.8 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KII93606.1 - 0.033 13.9 0.8 0.061 13.1 0.6 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF588 PF04535.7 KII93606.1 - 0.12 11.8 0.2 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) ABC2_membrane_2 PF12679.2 KII93606.1 - 0.18 10.6 3.0 0.27 10.0 2.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PEHE PF15275.1 KII93608.1 - 2.2e-05 24.8 1.2 2.2e-05 24.8 0.9 2.2 2 0 0 2 2 2 1 PEHE domain SAS4 PF15460.1 KII93608.1 - 8.6e-05 22.3 3.4 0.00022 21.0 2.4 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 ACT_7 PF13840.1 KII93609.1 - 5.4e-20 70.6 0.0 8.4e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 ACT domain Ribonuclease_T2 PF00445.13 KII93610.1 - 2.9e-40 137.9 0.0 4e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family TRI5 PF06330.6 KII93611.1 - 6.3e-22 77.7 0.0 8.3e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF4217 PF13959.1 KII93611.1 - 0.044 13.3 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Ribonuclease_T2 PF00445.13 KII93612.1 - 1.9e-41 141.7 0.0 2.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Gar1 PF04410.9 KII93613.1 - 2.3e-32 111.6 0.7 2.3e-32 111.6 0.5 2.3 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region EF_TS PF00889.14 KII93614.1 - 1.1e-18 67.4 0.0 2e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.26 KII93614.1 - 0.00047 19.9 0.0 0.00097 18.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Ceramidase PF05875.7 KII93615.1 - 4.5e-75 252.1 6.4 5.3e-75 251.9 4.4 1.0 1 0 0 1 1 1 1 Ceramidase HA2 PF04408.18 KII93616.1 - 2.1e-21 75.8 0.0 6.9e-21 74.1 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KII93616.1 - 1.5e-14 53.8 0.0 3.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KII93616.1 - 2e-08 33.9 0.0 5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII93616.1 - 8.1e-08 31.9 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KII93616.1 - 0.00058 19.9 0.1 0.0018 18.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KII93616.1 - 0.017 14.0 0.0 0.06 12.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 KII93616.1 - 0.029 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 KII93616.1 - 0.03 14.0 0.1 0.097 12.4 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KII93616.1 - 0.056 13.7 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 KII93616.1 - 0.072 12.7 0.6 0.28 10.8 0.2 2.2 2 1 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KII93616.1 - 0.096 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 KII93616.1 - 0.11 11.5 0.1 0.58 9.2 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin KaiC PF06745.8 KII93616.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 KII93616.1 - 0.2 10.5 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KII93616.1 - 0.22 11.4 0.0 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF592 PF04574.8 KII93616.1 - 0.24 10.9 0.0 0.48 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) OB_NTP_bind PF07717.11 KII93617.1 - 1.6e-30 105.2 0.0 5.5e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KII93617.1 - 4.4e-29 100.4 0.1 1.4e-28 98.8 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KII93617.1 - 2.6e-12 46.4 0.0 8.4e-12 44.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII93617.1 - 1.5e-06 27.8 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.18 KII93617.1 - 6e-06 26.2 0.2 1.4e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain T2SE PF00437.15 KII93617.1 - 0.0006 18.7 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 KII93617.1 - 0.0015 18.7 0.1 0.78 10.0 0.0 2.7 1 1 1 2 2 2 1 ABC transporter AAA_19 PF13245.1 KII93617.1 - 0.0042 16.8 0.1 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KII93617.1 - 0.0053 16.8 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KII93617.1 - 0.032 13.8 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KII93617.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_25 PF13481.1 KII93617.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KII93617.1 - 0.072 12.0 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KII93617.1 - 0.1 12.4 0.0 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NTF2 PF02136.15 KII93618.1 - 3.2e-11 43.6 0.0 6.1e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KII93618.1 - 1.9e-08 34.2 0.0 2.3e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Exo_endo_phos PF03372.18 KII93619.1 - 4e-24 85.9 0.3 5.3e-24 85.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3285 PF11688.3 KII93619.1 - 0.78 9.4 3.0 0.53 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) EmrE PF13536.1 KII93619.1 - 2.6 8.2 9.7 0.35 11.0 2.2 2.3 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Abhydrolase_3 PF07859.8 KII93620.1 - 2.4e-48 164.5 0.0 3.9e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KII93620.1 - 2.3e-15 56.1 0.0 2.2e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KII93620.1 - 6.6e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII93620.1 - 0.0072 15.0 0.0 0.91 8.1 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.16 KII93620.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_M24 PF00557.19 KII93622.1 - 3.9e-41 140.9 0.1 5e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Histone PF00125.19 KII93623.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII93623.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KII93623.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KII93623.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KII93623.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KII93623.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RibD_C PF01872.12 KII93624.1 - 8.4e-29 100.6 0.0 1.3e-28 99.9 0.0 1.3 1 1 0 1 1 1 1 RibD C-terminal domain RhoGEF PF00621.15 KII93626.1 - 6e-12 45.7 0.0 3.9e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain DUF3827 PF12877.2 KII93626.1 - 5.4 5.0 7.8 8.8 4.2 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NIF PF03031.13 KII93627.1 - 1.5e-23 83.2 0.0 1.3e-20 73.6 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KII93627.1 - 4.9e-11 42.3 0.2 6.2e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KII93627.1 - 1.7e-05 24.8 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CAF-1_p150 PF11600.3 KII93627.1 - 0.0036 16.7 8.5 0.0036 16.7 5.9 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal BSP PF04450.7 KII93628.1 - 5.2e-60 202.4 0.0 6e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KII93628.1 - 5.6e-07 29.6 0.1 1.3e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 KII93628.1 - 0.077 12.6 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 SprT-like family SnoaL_2 PF12680.2 KII93629.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain DUF1296 PF06972.6 KII93629.1 - 0.077 12.9 0.0 0.79 9.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Zn_clus PF00172.13 KII93630.1 - 9.7e-08 31.7 4.4 1.5e-07 31.1 3.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 KII93630.1 - 0.041 13.6 3.3 0.064 13.0 2.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Haem_bd PF14376.1 KII93630.1 - 0.097 12.3 3.5 0.17 11.5 2.4 1.4 1 0 0 1 1 1 0 Haem-binding domain IER PF05760.7 KII93630.1 - 5.5 6.8 16.6 72 3.1 11.5 2.0 1 1 0 1 1 1 0 Immediate early response protein (IER) HLH PF00010.21 KII93631.1 - 8.3e-05 22.2 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRCC PF10253.4 KII93631.1 - 0.52 10.9 4.1 0.75 10.4 2.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CDC27 PF09507.5 KII93631.1 - 7.2 5.7 7.3 9.4 5.3 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pkinase PF00069.20 KII93633.1 - 5.7e-65 219.0 0.0 1e-63 214.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93633.1 - 2e-34 118.8 0.0 3e-26 92.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII93633.1 - 4.3e-07 29.1 0.0 4.7e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KII93633.1 - 0.00038 20.2 1.8 0.01 15.5 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KII93633.1 - 0.011 14.6 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MMR_HSR1 PF01926.18 KII93634.1 - 2e-18 66.4 0.1 3e-18 65.8 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII93634.1 - 4.6e-11 42.2 0.0 7.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KII93634.1 - 1.1e-10 41.1 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain Miro PF08477.8 KII93634.1 - 0.001 19.5 0.0 0.0027 18.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KII93634.1 - 0.0037 17.1 0.2 0.12 12.1 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MCM PF00493.18 KII93634.1 - 0.063 12.0 0.1 0.14 10.8 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family ArgK PF03308.11 KII93634.1 - 0.067 11.9 0.1 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Lactamase_B_2 PF12706.2 KII93635.1 - 8.1e-11 41.8 0.2 2.8e-10 40.0 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KII93635.1 - 8.5e-11 41.8 0.3 1.7e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 KII93635.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Hist_deacetyl PF00850.14 KII93636.1 - 1.3e-82 277.5 0.0 2.3e-82 276.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DinB_2 PF12867.2 KII93637.1 - 1.9e-08 34.7 0.6 2.4e-08 34.3 0.4 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.7 KII93637.1 - 0.0054 16.4 0.2 0.0095 15.6 0.1 1.4 1 1 0 1 1 1 1 DinB family Complex1_49kDa PF00346.14 KII93637.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit YycC PF14174.1 KII93637.1 - 0.2 11.3 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 YycC-like protein ATP-grasp_2 PF08442.5 KII93638.1 - 3.7e-73 245.2 1.0 4.4e-73 244.9 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KII93638.1 - 8.6e-27 93.6 0.1 1.6e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KII93638.1 - 2.7e-12 46.4 0.1 1.3e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KII93638.1 - 0.00019 21.0 0.1 0.00075 19.1 0.0 2.0 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KII93638.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peripla_BP_2 PF01497.13 KII93638.1 - 0.046 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein CAF-1_p150 PF11600.3 KII93639.1 - 0.0012 18.3 11.8 0.0012 18.3 8.2 3.1 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal BCAS2 PF05700.6 KII93640.1 - 1.5e-63 214.2 2.0 1.7e-63 214.1 1.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CCDC155 PF14662.1 KII93640.1 - 0.0019 17.8 3.5 0.0031 17.1 2.4 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Baculo_PEP_C PF04513.7 KII93640.1 - 0.036 13.8 2.3 0.07 12.9 1.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GP41 PF00517.12 KII93640.1 - 0.07 12.6 1.2 0.099 12.1 0.8 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Prominin PF05478.6 KII93640.1 - 0.29 8.6 2.8 0.35 8.3 1.9 1.1 1 0 0 1 1 1 0 Prominin Cep57_CLD_2 PF14197.1 KII93640.1 - 0.36 10.7 6.4 1.1 9.2 0.6 2.9 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Nup54 PF13874.1 KII93640.1 - 0.9 9.1 6.9 0.23 11.0 2.0 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF1843 PF08898.5 KII93640.1 - 4.3 7.4 9.8 46 4.1 0.1 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF972 PF06156.8 KII93640.1 - 4.7 7.6 6.1 5.7 7.3 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Complex1_30kDa PF00329.14 KII93641.1 - 6.7e-35 119.4 0.0 1e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2413 PF10310.4 KII93642.1 - 1.3e-77 261.4 4.8 1.2e-76 258.4 3.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) TFIIF_alpha PF05793.7 KII93643.1 - 0.27 9.5 29.2 0.4 8.9 20.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MRP-L46 PF11788.3 KII93643.1 - 2.4 8.8 9.3 1 10.0 4.5 1.8 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Tim17 PF02466.14 KII93644.1 - 4.2e-23 81.7 0.1 7.5e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ras PF00071.17 KII93646.1 - 5.1e-51 172.2 0.1 5.9e-51 172.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII93646.1 - 2.9e-15 56.7 0.0 4.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII93646.1 - 5.8e-05 22.4 0.0 6.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII93646.1 - 9.9e-05 21.8 0.0 0.00027 20.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII93646.1 - 0.00074 19.4 0.0 0.00097 19.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII93646.1 - 0.0049 16.1 0.1 0.064 12.5 0.0 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.1 KII93646.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KII93646.1 - 0.067 12.0 0.1 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF1840 PF08895.6 KII93646.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) FAP PF07174.6 KII93647.1 - 4.1 6.6 10.1 4.7 6.4 7.0 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Oxidored_FMN PF00724.15 KII93648.1 - 2e-21 76.3 0.2 4.3e-21 75.2 0.1 1.5 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Methyltransf_23 PF13489.1 KII93649.1 - 3.1e-15 56.2 0.0 4.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII93649.1 - 2.5e-11 43.9 0.0 4.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII93649.1 - 3.1e-09 36.5 0.0 1.8e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII93649.1 - 2.5e-07 31.0 0.0 2e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII93649.1 - 4e-06 27.3 0.0 5.3e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KII93649.1 - 6.9e-06 24.6 0.0 0.00011 20.7 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 KII93649.1 - 9e-05 22.7 0.0 0.00039 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII93649.1 - 0.00011 21.3 0.0 0.0014 17.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 KII93649.1 - 0.00031 19.9 0.0 0.0018 17.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KII93649.1 - 0.00039 19.6 0.0 0.001 18.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 KII93649.1 - 0.00061 19.4 0.0 0.00095 18.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 KII93649.1 - 0.0025 17.2 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.7 KII93649.1 - 0.0058 16.2 0.0 0.024 14.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 KII93649.1 - 0.02 14.9 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KII93649.1 - 0.037 13.2 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase FtsJ PF01728.14 KII93649.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2215 PF10225.4 KII93651.1 - 0.31 10.4 1.0 0.35 10.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ribonuc_red_sm PF00268.16 KII93652.1 - 7.3e-100 333.5 0.0 9.1e-100 333.2 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain F-box-like PF12937.2 KII93657.1 - 9.7e-06 25.2 0.8 6.4e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII93657.1 - 1.3e-05 24.7 2.5 3.1e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 F-box domain Pkinase PF00069.20 KII93658.1 - 9.4e-40 136.3 0.0 1.2e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93658.1 - 5.6e-10 38.7 0.0 2e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KII93658.1 - 0.00054 18.8 0.1 0.00098 18.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KII93658.1 - 0.044 12.7 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF2764 PF10962.3 KII93658.1 - 0.088 12.0 0.2 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) Pkinase PF00069.20 KII93660.1 - 2.4e-08 33.4 0.0 8.5e-08 31.6 0.0 1.8 1 1 1 2 2 2 2 Protein kinase domain Yippee-Mis18 PF03226.9 KII93662.1 - 6.3e-23 80.6 1.3 7.1e-23 80.4 0.9 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 KII93662.1 - 0.051 13.5 2.2 0.23 11.4 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme AlcCBM31 PF11606.3 KII93662.1 - 0.066 13.1 0.1 9.5 6.2 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein Peptidase_C48 PF02902.14 KII93665.1 - 1.1e-36 126.5 0.7 2.1e-34 119.0 0.5 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SNARE PF05739.14 KII93666.1 - 3.6e-08 32.9 0.5 4.6e-08 32.6 0.4 1.1 1 0 0 1 1 1 1 SNARE domain DUF4234 PF14018.1 KII93666.1 - 0.0072 16.0 1.0 0.011 15.4 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) Use1 PF09753.4 KII93666.1 - 0.023 14.1 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Sec20 PF03908.8 KII93666.1 - 0.039 13.6 0.1 0.086 12.5 0.0 1.5 1 1 0 1 1 1 0 Sec20 DUF2120 PF09893.4 KII93666.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) TMEMspv1-c74-12 PF11044.3 KII93667.1 - 5.7 6.5 11.9 0.76 9.3 0.7 3.6 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF1772 PF08592.6 KII93667.1 - 7.5 6.2 9.4 1.4 8.6 3.4 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) PTH2 PF01981.11 KII93668.1 - 1.4e-40 137.5 0.0 1.8e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sgf11 PF08209.6 KII93669.1 - 3.2e-14 51.9 0.4 5.6e-14 51.1 0.3 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Fungal_trans PF04082.13 KII93670.1 - 1.5e-32 112.5 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII93670.1 - 1e-06 28.5 9.5 1.9e-06 27.6 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIPSNAP PF07978.8 KII93671.1 - 1.8e-29 101.6 2.7 2.8e-25 88.2 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP F5_F8_type_C PF00754.20 KII93672.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Proteasome PF00227.21 KII93673.1 - 1.1e-37 129.1 0.0 1.3e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MoaC PF01967.16 KII93674.1 - 8.1e-42 142.1 1.0 1e-38 132.0 0.7 2.5 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KII93674.1 - 1.6e-31 108.6 0.0 2.9e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KII93674.1 - 6.7e-22 78.4 0.0 1.2e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KII93674.1 - 6.2e-08 32.8 0.0 2.6e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KII93674.1 - 2e-06 27.8 0.0 5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain HpcH_HpaI PF03328.9 KII93675.1 - 5.5e-34 116.9 0.0 6.6e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 KII93675.1 - 0.04 12.5 0.4 0.073 11.6 0.3 1.4 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain FR47 PF08445.5 KII93676.1 - 7.7e-08 31.9 0.1 1.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KII93676.1 - 7.5e-07 29.1 0.2 1.3e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII93676.1 - 1.3e-06 28.4 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII93676.1 - 2.6e-06 27.5 0.1 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII93676.1 - 1.8e-05 24.5 0.2 3.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KII93676.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF953 PF06110.6 KII93677.1 - 1.8e-20 72.5 0.0 1.9e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Mucin PF01456.12 KII93678.1 - 4.1 7.1 24.1 3.7 7.3 6.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Mito_carr PF00153.22 KII93679.1 - 2.3e-66 219.5 0.8 1.6e-24 85.4 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KII93679.1 - 2.8e-16 59.3 3.1 3.6e-07 30.2 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KII93679.1 - 1e-14 52.6 5.8 2e-05 23.5 0.0 6.3 7 0 0 7 7 7 2 EF hand EF-hand_6 PF13405.1 KII93679.1 - 6.1e-14 50.5 3.7 0.00041 19.9 0.0 6.0 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.1 KII93679.1 - 5e-13 48.4 0.8 0.00074 19.0 0.0 5.5 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 KII93679.1 - 7.3e-09 34.5 1.6 0.00041 19.5 0.0 3.9 3 0 0 3 3 3 2 EF hand Met_10 PF02475.11 KII93680.1 - 2.6e-66 223.0 0.0 3.4e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KII93680.1 - 2.7e-05 24.1 0.0 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII93680.1 - 0.0047 17.4 0.0 0.0098 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII93680.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TatD_DNase PF01026.16 KII93681.1 - 1.6e-21 76.7 0.0 2.2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.3 KII93682.1 - 8.7e-15 54.5 1.7 8.7e-15 54.5 1.2 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus AAA_13 PF13166.1 KII93682.1 - 0.016 13.7 0.4 0.019 13.4 0.3 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 KII93682.1 - 0.016 15.8 0.5 0.38 11.5 0.1 2.7 2 1 1 3 3 3 0 Occludin homology domain DUF4201 PF13870.1 KII93682.1 - 0.036 13.4 0.2 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 KII93682.1 - 0.037 13.8 3.8 0.032 14.0 1.2 1.8 2 0 0 2 2 2 0 Tropomyosin like Sec20 PF03908.8 KII93682.1 - 0.091 12.4 0.8 0.34 10.6 0.0 2.2 3 0 0 3 3 3 0 Sec20 Rootletin PF15035.1 KII93682.1 - 0.094 12.6 4.5 1.9 8.4 0.2 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3678 PF12435.3 KII93682.1 - 0.17 11.4 2.7 0.54 9.8 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) CCDC-167 PF15188.1 KII93682.1 - 0.32 10.9 2.8 0.61 10.0 0.5 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 FlgN PF05130.7 KII93682.1 - 0.86 9.8 5.7 0.42 10.8 1.7 2.0 1 1 1 2 2 2 0 FlgN protein AATF-Che1 PF13339.1 KII93682.1 - 0.98 9.5 5.9 7.7 6.6 4.1 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor HalX PF08663.5 KII93682.1 - 1.3 9.0 6.2 2.2 8.2 3.2 2.1 1 1 0 1 1 1 0 HalX domain CorA PF01544.13 KII93682.1 - 3 6.8 6.6 0.29 10.1 0.2 2.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein B-block_TFIIIC PF04182.7 KII93683.1 - 3e-09 36.5 0.6 5.5e-08 32.5 0.1 3.1 5 0 0 5 5 5 1 B-block binding subunit of TFIIIC HTH_27 PF13463.1 KII93683.1 - 0.0034 17.6 0.0 0.26 11.6 0.0 3.6 4 0 0 4 4 4 1 Winged helix DNA-binding domain MarR PF01047.17 KII93683.1 - 0.018 14.7 0.2 0.5 10.1 0.0 3.2 3 0 0 3 3 3 0 MarR family HTH_24 PF13412.1 KII93683.1 - 0.03 13.7 1.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PRELI PF04707.9 KII93684.1 - 9.4e-37 126.0 0.0 1.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ABC_membrane_2 PF06472.10 KII93685.1 - 3.5e-87 292.1 0.9 5e-87 291.6 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KII93685.1 - 6.4e-17 62.1 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KII93685.1 - 0.00038 20.5 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KII93685.1 - 0.01 16.1 0.3 0.042 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KII93685.1 - 0.015 15.3 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KII93685.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KII93685.1 - 0.04 13.1 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KII93685.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 KII93685.1 - 0.22 10.1 0.1 0.35 9.4 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF641 PF04859.7 KII93686.1 - 0.00046 19.9 16.1 0.32 10.7 0.1 4.6 2 1 3 5 5 5 2 Plant protein of unknown function (DUF641) ATG16 PF08614.6 KII93686.1 - 0.0066 16.2 9.6 0.0066 16.2 6.7 3.3 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 KII93686.1 - 0.0067 16.2 7.5 0.0067 16.2 5.2 4.3 1 1 2 4 4 4 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 KII93686.1 - 0.027 14.2 28.9 2.6 7.7 0.2 5.1 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding LURAP PF14854.1 KII93686.1 - 0.029 14.0 10.9 0.38 10.4 0.2 4.2 1 1 4 5 5 5 0 Leucine rich adaptor protein IFT57 PF10498.4 KII93686.1 - 0.041 12.6 18.2 0.031 13.0 2.3 2.8 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Shugoshin_N PF07558.6 KII93686.1 - 0.27 10.9 10.4 5.4 6.8 0.0 4.4 5 0 0 5 5 4 0 Shugoshin N-terminal coiled-coil region Phage_GP20 PF06810.6 KII93686.1 - 0.36 10.2 14.3 0.48 9.8 1.2 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 KID PF02524.9 KII93686.1 - 0.46 10.8 1.8 2.9e+02 2.4 0.3 4.4 3 0 0 3 3 3 0 KID repeat Atg14 PF10186.4 KII93686.1 - 1.1 8.1 23.5 1.4 7.8 10.6 2.7 1 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin_2 PF14523.1 KII93686.1 - 1.5 8.9 14.4 2.2 8.3 0.6 3.6 2 1 1 3 3 3 0 Syntaxin-like protein Occludin_ELL PF07303.8 KII93686.1 - 1.7 9.4 6.6 1.2 9.9 0.8 2.7 1 1 0 2 2 2 0 Occludin homology domain Bap31 PF05529.7 KII93686.1 - 2.4 7.5 13.2 5.8 6.3 0.3 3.2 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like FlaC_arch PF05377.6 KII93686.1 - 2.7 7.9 9.8 7.8 6.4 1.6 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 KII93686.1 - 3.4 7.9 8.5 26 5.1 1.8 4.0 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein HR1 PF02185.11 KII93686.1 - 3.5 7.4 14.9 1.6 8.4 0.4 4.4 1 1 4 5 5 5 0 Hr1 repeat GAS PF13851.1 KII93686.1 - 3.7 6.6 22.1 0.054 12.6 4.3 2.9 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Sec2p PF06428.6 KII93686.1 - 4.2 7.2 15.6 1.1 9.1 3.5 3.6 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Reo_sigmaC PF04582.7 KII93686.1 - 4.6 6.3 10.3 5.3 6.1 5.0 2.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF310 PF03750.8 KII93686.1 - 4.8 7.4 5.5 1.1 9.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF310) Fzo_mitofusin PF04799.8 KII93686.1 - 5.5 6.3 13.8 0.2 11.0 1.5 3.2 1 1 4 5 5 5 0 fzo-like conserved region IncA PF04156.9 KII93686.1 - 6 6.4 29.8 4.6e+03 -3.0 20.7 2.9 1 1 0 1 1 1 0 IncA protein NT5C PF06941.7 KII93688.1 - 7.3e-12 45.1 0.6 4.2e-11 42.7 0.0 2.3 2 1 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 KII93688.1 - 2.2e-05 24.7 0.1 7.7e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KII93688.1 - 0.0039 17.3 0.0 0.0053 16.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII93688.1 - 0.0058 17.0 0.0 0.019 15.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KII93688.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KII93688.1 - 0.02 14.2 0.1 0.064 12.6 0.1 1.7 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LNS2 PF08235.8 KII93688.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) SecY PF00344.15 KII93689.1 - 3.7e-97 325.3 10.1 4.7e-97 325.0 7.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KII93689.1 - 1.1e-19 69.5 0.1 6e-19 67.2 0.1 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p Pro_CA PF00484.14 KII93690.1 - 1e-25 90.5 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase RINT1_TIP1 PF04437.8 KII93691.1 - 1e-74 251.9 0.0 2.4e-73 247.3 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family GrpE PF01025.14 KII93691.1 - 0.11 12.0 1.9 0.29 10.6 1.3 1.6 1 0 0 1 1 1 0 GrpE WASH-7_mid PF14744.1 KII93691.1 - 0.31 9.8 0.9 1.1 7.9 0.0 1.9 2 0 0 2 2 2 0 WASH complex subunit 7 Prominin PF05478.6 KII93691.1 - 1.3 6.4 2.6 1.8 6.0 1.8 1.1 1 0 0 1 1 1 0 Prominin Kinesin PF00225.18 KII93692.1 - 5.9e-80 268.4 0.0 9.5e-80 267.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Egg_lysin PF01303.12 KII93692.1 - 0.057 13.4 0.1 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) Nop14 PF04147.7 KII93692.1 - 0.95 7.2 37.4 5.7 4.7 26.5 1.8 2 1 0 2 2 2 0 Nop14-like family Spc7 PF08317.6 KII93693.1 - 3.2e-44 150.9 6.2 5e-44 150.3 4.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4315 PF14193.1 KII93693.1 - 0.0067 16.3 4.7 2.3 8.1 1.9 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4315) Spc7_C2 PF15577.1 KII93693.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Spc7_C2 RasGAP_C PF03836.10 KII93693.1 - 0.23 11.1 4.2 0.43 10.2 2.9 1.4 1 0 0 1 1 1 0 RasGAP C-terminus DUF342 PF03961.8 KII93693.1 - 0.48 8.7 6.5 0.77 8.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 KII93693.1 - 3.5 6.4 6.9 7 5.5 4.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DIE2_ALG10 PF04922.7 KII93695.1 - 4.4e-95 318.9 12.8 5.7e-95 318.5 8.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family TauD PF02668.11 KII93696.1 - 1e-51 176.0 0.2 1.3e-51 175.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0128 PF03673.8 KII93696.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Methyltransf_2 PF00891.13 KII93697.1 - 7.3e-34 117.0 0.0 1.1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII93697.1 - 5.7e-06 26.8 0.0 3.1e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII93697.1 - 0.017 14.7 0.0 0.054 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KII93697.1 - 0.061 12.7 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Colicin_C PF12106.3 KII93697.1 - 0.071 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain Transp_cyt_pur PF02133.10 KII93698.1 - 4e-83 279.4 33.8 4.7e-83 279.1 23.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OPT PF03169.10 KII93700.1 - 2.2e-190 634.2 56.6 2.5e-190 634.0 39.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Prp19 PF08606.6 KII93701.1 - 9.4e-31 105.3 1.1 2.1e-30 104.2 0.7 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KII93701.1 - 5e-21 73.7 0.2 2.4e-07 30.3 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat U-box PF04564.10 KII93701.1 - 5.1e-06 26.3 0.0 1.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KII93701.1 - 2.4e-05 23.7 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 KII93701.1 - 0.0047 16.1 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Glu_cyclase_2 PF05096.7 KII93701.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase DUF3312 PF11768.3 KII93701.1 - 0.078 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) TPR_11 PF13414.1 KII93702.1 - 2.8e-14 52.5 1.2 5.1e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KII93702.1 - 3e-13 48.7 0.0 1.3e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII93702.1 - 8.6e-10 38.0 0.3 0.0013 18.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII93702.1 - 2.4e-09 36.3 0.0 4.8e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII93702.1 - 7.5e-08 32.8 7.3 0.00014 22.4 0.6 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII93702.1 - 1.8e-05 24.9 0.1 0.0041 17.6 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII93702.1 - 3.5e-05 23.2 0.4 0.0017 18.0 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KII93702.1 - 0.00034 20.1 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII93702.1 - 0.00068 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII93702.1 - 0.00085 19.6 0.1 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KII93702.1 - 0.047 13.8 0.1 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KII93702.1 - 0.1 12.4 0.1 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Toluene_X PF03349.11 KII93702.1 - 0.73 8.1 4.2 1.3 7.2 2.9 1.4 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) TPR_6 PF13174.1 KII93702.1 - 9.6 6.9 6.7 2.3 8.8 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 KII93703.1 - 3.4e-33 113.4 5.9 2.4e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII93703.1 - 1.1e-31 108.7 4.6 7.5e-14 51.5 0.2 3.7 2 1 2 4 4 4 3 Myb-like DNA-binding domain zf-C2H2 PF00096.21 KII93703.1 - 0.26 11.7 3.5 1.5 9.3 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.27 KII93704.1 - 2.4e-42 141.3 12.1 2.2e-10 40.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 KII93704.1 - 0.0002 20.9 0.0 0.0083 15.6 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 KII93704.1 - 0.04 12.0 0.3 0.7 7.9 0.2 2.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KII93704.1 - 0.046 11.9 0.0 2.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain MCM PF00493.18 KII93706.1 - 1.1e-125 418.8 0.0 1.7e-125 418.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KII93706.1 - 9.6e-24 84.1 0.1 2.1e-23 83.0 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KII93706.1 - 4.5e-08 32.5 0.0 1.2e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KII93706.1 - 0.0039 16.7 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KII93706.1 - 0.0061 16.0 0.1 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 KII93706.1 - 0.077 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_26 PF13659.1 KII93707.1 - 2.8e-09 37.0 0.1 4.2e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII93707.1 - 7.3e-07 28.7 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain C2 PF00168.25 KII93708.1 - 5.3e-75 247.3 13.8 6.7e-15 54.7 0.0 6.2 7 0 0 7 7 7 5 C2 domain Mito_carr PF00153.22 KII93709.1 - 2.9e-21 74.9 0.0 2e-05 24.1 0.0 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein NUDIX PF00293.23 KII93710.1 - 6.5e-09 35.5 0.0 1.6e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 KII93711.1 - 1.1e-51 175.5 0.0 6.9e-51 172.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93711.1 - 8.7e-39 133.1 0.0 3.9e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII93711.1 - 0.0039 16.2 0.0 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII93711.1 - 0.024 14.3 0.2 0.33 10.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MitMem_reg PF13012.1 KII93712.1 - 2.6e-22 79.0 0.0 3.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KII93712.1 - 3.7e-12 45.9 0.0 7.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4149 PF13664.1 KII93713.1 - 9.8e-18 64.0 2.5 9.8e-18 64.0 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) LRR_9 PF14580.1 KII93714.1 - 2.7e-55 186.6 0.0 4.2e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KII93714.1 - 1.6e-13 49.9 11.2 1.1e-07 31.2 0.8 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII93714.1 - 1.3e-11 44.1 9.7 6.4e-08 32.2 2.5 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KII93714.1 - 0.00034 20.3 2.2 17 6.2 0.0 4.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 KII93714.1 - 0.003 17.3 6.7 6.1 7.2 0.1 4.9 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 KII93714.1 - 0.18 11.9 6.0 12 6.3 0.6 4.0 4 1 1 5 5 5 0 Leucine Rich repeat Syja_N PF02383.13 KII93715.1 - 1.8e-84 283.2 0.0 3.2e-84 282.4 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain DUF2135 PF09906.4 KII93716.1 - 0.038 13.9 0.4 0.072 13.0 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) NPL4 PF05021.10 KII93717.1 - 1e-96 323.7 0.0 1.3e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KII93717.1 - 7.3e-61 204.1 0.0 1.2e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KII93717.1 - 1.9e-05 24.8 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.10 KII93718.1 - 3.9e-09 36.1 9.4 1.3e-08 34.5 6.4 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KII93718.1 - 2.5e-05 24.1 8.3 0.00011 22.1 5.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 KII93718.1 - 0.0016 16.7 11.9 0.0022 16.3 8.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Zwint PF15556.1 KII93718.1 - 0.023 13.9 1.5 0.038 13.2 1.0 1.3 1 0 0 1 1 1 0 ZW10 interactor bZIP_Maf PF03131.12 KII93718.1 - 0.58 10.4 7.2 0.092 13.0 2.1 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF2216 PF10226.4 KII93718.1 - 0.63 9.5 7.4 0.05 13.1 1.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) Pneumo_att_G PF05539.6 KII93718.1 - 3 7.1 7.7 0.4 9.9 1.7 1.9 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G CHCH PF06747.8 KII93719.1 - 7.5e-07 28.9 2.5 1e-06 28.5 1.7 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KII93719.1 - 0.0029 17.6 0.9 0.0049 16.8 0.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GDPD PF03009.12 KII93720.1 - 2.3e-35 122.3 0.0 2.8e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KII93720.1 - 2.5e-06 27.4 0.0 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family UCR_TM PF02921.9 KII93721.1 - 1.7e-18 66.5 0.5 3.4e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KII93721.1 - 3.4e-16 58.5 0.1 5.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase PF00069.20 KII93725.1 - 1.1e-41 142.7 0.0 8.1e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII93725.1 - 1e-10 41.1 0.0 2.2e-05 23.6 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KII93725.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MCM PF00493.18 KII93726.1 - 1.5e-141 470.9 0.1 2e-141 470.5 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KII93726.1 - 1.3e-18 67.5 0.0 3.8e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KII93726.1 - 6.3e-07 28.7 0.0 0.00024 20.3 0.0 2.6 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KII93726.1 - 9.9e-05 22.0 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KII93726.1 - 0.0006 19.4 0.2 0.0029 17.2 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KII93726.1 - 0.0076 16.6 0.2 0.059 13.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 KII93726.1 - 0.034 14.3 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF134 PF02001.11 KII93726.1 - 0.097 12.5 0.1 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF134 NAP PF00956.13 KII93727.1 - 7.8e-33 113.6 0.1 7.8e-33 113.6 0.1 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 KII93727.1 - 1.1 9.4 8.9 0.16 12.0 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Polysacc_deac_1 PF01522.16 KII93728.1 - 7e-30 103.2 0.0 1.4e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KII93728.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DASH_Dad2 PF08654.5 KII93728.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 ADH_N PF08240.7 KII93729.1 - 1.5e-25 89.0 4.6 2.8e-25 88.2 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII93729.1 - 2.2e-19 69.2 0.0 3.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII93729.1 - 0.0012 19.7 0.0 0.0021 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KII93729.1 - 0.0094 15.5 0.1 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CPSase_L_chain PF00289.17 KII93729.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pex16 PF08610.5 KII93730.1 - 6.4e-73 245.6 0.1 7.2e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Cep57_CLD_2 PF14197.1 KII93731.1 - 0.016 15.1 4.9 0.053 13.4 3.4 2.0 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Sulfatase PF00884.18 KII93731.1 - 0.055 12.6 0.1 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Sulfatase HD_3 PF13023.1 KII93731.1 - 0.057 13.1 2.1 0.1 12.3 1.5 1.3 1 0 0 1 1 1 0 HD domain APG6 PF04111.7 KII93731.1 - 0.089 11.8 5.2 0.14 11.1 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KII93731.1 - 0.13 12.1 5.0 0.09 12.5 1.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KII93731.1 - 0.15 12.4 1.3 0.39 11.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Troponin-I_N PF11636.3 KII93731.1 - 1.1 9.0 8.6 0.091 12.4 1.8 2.4 2 0 0 2 2 2 0 Troponin I residues 1-32 ICE2 PF08426.5 KII93732.1 - 4.6e-24 84.8 25.3 3.7e-13 48.8 7.5 3.1 1 1 1 2 2 2 2 ICE2 Peptidase_S10 PF00450.17 KII93733.1 - 3.1e-89 300.0 0.5 3.8e-89 299.7 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KII93733.1 - 0.041 13.7 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family MoaE PF02391.12 KII93734.1 - 1.9e-31 108.2 0.3 2.3e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 MoaE protein Indigoidine_A PF04227.7 KII93735.1 - 2.1e-120 401.3 0.2 4.1e-120 400.4 0.1 1.5 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KII93735.1 - 2e-20 73.1 0.0 6e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ResIII PF04851.10 KII93736.1 - 9.7e-18 64.6 0.0 2.3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KII93736.1 - 9.9e-15 54.4 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII93736.1 - 1.9e-14 53.3 0.0 4.4e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KII93736.1 - 3.5e-06 26.0 0.0 7.9e-06 24.8 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.4 KII93736.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KII93736.1 - 0.0024 18.0 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD_2 PF06733.10 KII93736.1 - 0.05 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 DUF1104 PF06518.6 KII93736.1 - 0.15 12.1 1.9 0.47 10.6 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Mito_carr PF00153.22 KII93737.1 - 3.2e-63 209.4 5.4 3.4e-22 77.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.3 KII93737.1 - 0.15 11.8 0.1 1 9.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) PINIT PF14324.1 KII93738.1 - 1.7e-39 135.1 1.9 2.8e-39 134.4 1.3 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KII93738.1 - 5.1e-18 64.3 8.1 9.5e-18 63.4 5.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KII93738.1 - 2.3e-06 27.0 3.0 5.6e-06 25.7 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 KII93738.1 - 0.088 12.2 0.3 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif SAP PF02037.22 KII93738.1 - 0.13 11.8 1.4 0.23 11.0 0.1 2.1 3 0 0 3 3 3 0 SAP domain CS PF04969.11 KII93739.1 - 1.7e-19 70.1 0.3 3e-19 69.3 0.2 1.4 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.1 KII93739.1 - 1.3 9.4 7.3 0.79 10.1 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4413 PF14372.1 KII93741.1 - 2e-06 27.7 0.1 2.4e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 KII93742.1 - 2.8e-07 30.0 0.1 3.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NUC153 PF08159.7 KII93743.1 - 2.4e-13 49.3 1.9 2.4e-13 49.3 1.3 4.0 4 0 0 4 4 4 2 NUC153 domain DUF1648 PF07853.6 KII93744.1 - 2.3e-05 23.8 0.0 64 3.1 0.0 6.0 6 0 0 6 6 6 4 Protein of unknown function (DUF1648) MFS_1_like PF12832.2 KII93744.1 - 2.4 7.9 4.5 5.3e+02 0.5 0.0 5.1 7 0 0 7 7 7 0 MFS_1 like family Cupin_2 PF07883.6 KII93745.1 - 2.8e-07 29.9 0.0 4.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DUF348 PF03990.9 KII93745.1 - 0.055 13.0 1.2 0.15 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF348) Auxin_BP PF02041.11 KII93745.1 - 0.072 12.5 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein adh_short PF00106.20 KII93746.1 - 7.8e-26 90.9 0.2 1e-25 90.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII93746.1 - 3.9e-24 85.7 0.0 4.6e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII93746.1 - 1.3e-11 44.5 0.1 1.8e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 KII93746.1 - 0.061 13.1 0.2 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KII93747.1 - 5.1e-48 162.5 0.2 7.5e-48 162.0 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KII93747.1 - 1.5e-09 38.1 1.4 2.9e-09 37.2 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KII93747.1 - 5.3e-06 26.3 0.0 9.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvC PF01450.14 KII93747.1 - 2.1e-05 24.5 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KII93747.1 - 0.00014 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KII93747.1 - 0.00096 18.9 0.2 0.015 15.0 0.1 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 KII93747.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 KII93747.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4214 PF13946.1 KII93748.1 - 0.023 14.3 1.1 8.4 6.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4214) SseC PF04888.7 KII93748.1 - 7.4 5.8 15.4 2.4 7.4 4.0 2.9 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family CorA PF01544.13 KII93749.1 - 2.1e-22 79.5 0.8 6.4e-12 45.0 0.0 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF998 PF06197.8 KII93749.1 - 0.03 13.6 2.0 0.17 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) PIG-U PF06728.8 KII93749.1 - 0.051 12.4 0.1 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF947 PF06102.7 KII93750.1 - 3.6e-37 127.7 16.0 5.1e-37 127.2 11.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) TRP PF06011.7 KII93751.1 - 0.00034 19.3 0.2 0.00034 19.3 0.2 2.0 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel GMC_oxred_N PF00732.14 KII93752.1 - 3.5e-60 203.6 0.0 4.6e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KII93752.1 - 6.4e-34 117.3 0.1 3.3e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KII93752.1 - 3.3e-06 26.2 0.0 0.0017 17.3 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII93752.1 - 0.00018 20.5 0.2 0.034 13.0 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KII93752.1 - 0.00068 19.6 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KII93752.1 - 0.002 17.0 0.1 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Abhydrolase_6 PF12697.2 KII93753.1 - 2.8e-22 79.7 2.5 3.2e-22 79.5 1.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII93753.1 - 1.5e-06 28.0 0.0 2.9e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 KII93754.1 - 4.1e-67 226.7 0.0 5.1e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 KII93755.1 - 3e-53 180.9 0.1 3.9e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KII93755.1 - 0.003 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Prenyltransf PF01255.14 KII93756.1 - 0.055 12.5 0.0 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase SNAP PF14938.1 KII93757.1 - 5.9e-108 360.3 15.8 6.7e-108 360.1 11.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KII93757.1 - 1.5e-05 24.5 16.7 0.045 13.3 0.8 4.0 3 2 1 4 4 4 3 TPR repeat TPR_7 PF13176.1 KII93757.1 - 2.1e-05 23.9 9.4 0.082 12.7 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII93757.1 - 0.0038 17.1 4.3 0.0038 17.1 3.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.1 KII93757.1 - 0.0073 15.2 3.8 0.023 13.5 2.0 2.1 2 1 0 2 2 2 1 Spatacsin C-terminus TPR_16 PF13432.1 KII93757.1 - 0.0096 16.5 14.4 0.22 12.2 0.4 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF410 PF04190.8 KII93757.1 - 0.013 15.0 0.2 0.5 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_8 PF13181.1 KII93757.1 - 0.013 15.2 6.7 1.8 8.5 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII93757.1 - 0.022 15.1 11.8 4.7 7.8 0.0 5.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII93757.1 - 0.062 13.2 17.0 9 6.4 0.2 6.0 4 1 1 6 6 6 0 Tetratricopeptide repeat PGM_PMM_I PF02878.11 KII93758.1 - 4.6e-18 65.0 0.0 5.6e-08 32.3 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KII93758.1 - 1.1e-13 51.4 0.0 4.7e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KII93758.1 - 9.2e-11 41.6 0.2 2e-09 37.2 0.2 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KII93758.1 - 0.0095 15.9 0.2 0.023 14.7 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III GATase_4 PF13230.1 KII93759.1 - 8.5e-22 77.1 0.0 1.4e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KII93759.1 - 2.7e-09 37.0 0.0 4.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KII93759.1 - 9.5e-09 34.4 0.0 7.8e-07 28.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II RRM_1 PF00076.17 KII93760.1 - 1.5e-41 139.8 0.4 4.3e-21 74.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII93760.1 - 2.7e-32 110.5 0.1 8e-15 54.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII93760.1 - 5.5e-25 86.9 0.1 8.3e-11 41.5 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KII93760.1 - 5.3e-20 71.4 0.2 1.2e-19 70.3 0.2 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 KII93760.1 - 2.7e-06 27.1 0.7 0.00093 19.0 0.0 2.8 2 1 1 3 3 3 2 RNA binding motif Zn_clus PF00172.13 KII93761.1 - 1.9e-07 30.8 10.6 3.3e-07 30.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KII93761.1 - 8.6e-06 24.8 0.1 1.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TB2_DP1_HVA22 PF03134.14 KII93764.1 - 9.4e-22 76.5 8.2 1.3e-21 76.1 5.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.9 KII93764.1 - 0.00084 19.2 3.1 0.0014 18.5 2.1 1.4 1 0 0 1 1 1 1 GtrA-like protein Sec3_C PF09763.4 KII93765.1 - 4.4e-167 557.3 0.8 6.5e-167 556.7 0.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KII93765.1 - 7.3e-20 70.6 0.0 1.6e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 KII93765.1 - 0.00041 19.0 4.5 0.0035 15.9 3.1 2.1 1 1 0 1 1 1 1 Vps52 / Sac2 family DUF4451 PF14616.1 KII93767.1 - 5.2e-05 23.0 1.1 8.2e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Eapp_C PF10238.4 KII93767.1 - 0.14 12.0 1.6 0.26 11.1 1.1 1.5 1 1 0 1 1 1 0 E2F-associated phosphoprotein DUF3827 PF12877.2 KII93767.1 - 0.35 8.9 5.3 0.48 8.4 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Homeobox PF00046.24 KII93768.1 - 2.1e-07 30.4 0.0 4.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain FAM220 PF15487.1 KII93768.1 - 9.5 5.5 8.1 15 4.8 5.6 1.2 1 0 0 1 1 1 0 FAM220 family Glyco_transf_21 PF13506.1 KII93769.1 - 1.9e-21 76.1 1.0 1.9e-16 59.8 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KII93769.1 - 6.7e-15 55.5 0.0 9.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KII93769.1 - 0.055 13.1 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 TatD_DNase PF01026.16 KII93770.1 - 3.5e-46 157.4 0.0 4.7e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 KII93770.1 - 0.0032 17.0 0.0 0.13 11.7 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase Thiolase_N PF00108.18 KII93771.1 - 2.6e-70 236.4 0.1 4.2e-70 235.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KII93771.1 - 9.3e-47 157.4 0.3 2.5e-46 156.0 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KII93771.1 - 7.8e-07 28.6 2.7 4.1e-05 23.1 0.1 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KII93771.1 - 0.00033 20.2 0.3 0.0031 17.0 0.2 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KII93771.1 - 0.0025 17.8 0.1 0.0091 15.9 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Hepar_II_III PF07940.8 KII93772.1 - 2.7e-09 36.9 0.9 6.3e-09 35.8 0.6 1.6 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF1180 PF06679.7 KII93773.1 - 0.00064 19.6 9.1 0.00064 19.6 6.3 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1180) HTH_21 PF13276.1 KII93774.1 - 2.1e-05 24.4 0.0 3.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 HTH-like domain Ima1_N PF09779.4 KII93775.1 - 3.7e-29 101.8 1.1 6.2e-29 101.1 0.7 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain zf-RING_3 PF14369.1 KII93775.1 - 1.5 8.8 10.2 2.7 8.0 3.6 2.7 2 0 0 2 2 2 0 zinc-finger SNAPc_SNAP43 PF09808.4 KII93776.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SKN1 PF03935.10 KII93777.1 - 3.9e-193 642.2 2.9 4.5e-193 641.9 2.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3976 PF13121.1 KII93777.1 - 0.2 11.5 0.6 0.34 10.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) UQ_con PF00179.21 KII93778.1 - 4.1e-19 68.4 0.0 8.1e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HIRAN PF08797.6 KII93779.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 HIRAN domain F-box PF00646.28 KII93780.1 - 1.2e-06 28.0 0.5 2.7e-06 26.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII93780.1 - 0.0014 18.3 0.5 0.0029 17.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like DUF619 PF04768.8 KII93781.1 - 8.1e-34 116.4 0.1 7e-19 67.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) AA_kinase PF00696.23 KII93781.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Amino acid kinase family YscO PF07321.7 KII93782.1 - 0.029 14.1 0.3 0.047 13.5 0.2 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Trypsin_2 PF13365.1 KII93782.1 - 0.12 12.3 0.1 2.4 8.1 0.1 2.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Mito_carr PF00153.22 KII93784.1 - 7.6e-66 217.8 4.6 1e-22 79.6 0.2 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Fasciclin PF02469.17 KII93784.1 - 8e-65 216.6 0.0 2.3e-14 53.4 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Rav1p_C PF12234.3 KII93785.1 - 2.5e-186 620.5 0.0 3.5e-186 620.1 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal GDI PF00996.13 KII93786.1 - 7.9e-209 693.4 0.1 9.1e-209 693.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PhnJ PF06007.6 KII93786.1 - 0.062 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ TipAS PF07739.8 KII93786.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain RE_MjaI PF09568.5 KII93787.1 - 0.067 12.7 0.5 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 MjaI restriction endonuclease Aldedh PF00171.17 KII93788.1 - 1.3e-129 432.5 0.2 1.5e-129 432.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII93788.1 - 0.0047 15.7 0.0 0.0078 14.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LMWPc PF01451.16 KII93789.1 - 3.3e-35 121.4 0.0 3.7e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3BGR PF04908.10 KII93790.1 - 6.5e-13 48.4 0.0 1.4e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein FANCI_S1-cap PF14674.1 KII93790.1 - 0.058 13.4 0.2 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 FANCI solenoid 1 cap adh_short PF00106.20 KII93791.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII93791.1 - 1.3e-19 70.9 0.0 2.4e-19 70.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII93791.1 - 7.9e-08 32.1 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII93791.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Seipin PF06775.9 KII93792.1 - 1.5e-17 63.7 0.0 3.3e-16 59.3 0.0 2.1 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF4282 PF14110.1 KII93792.1 - 1.1 9.5 6.3 0.17 12.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) LCCL PF03815.14 KII93796.1 - 2.1e-15 56.4 0.0 3.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF3094 PF11293.3 KII93796.1 - 0.016 14.6 0.4 0.016 14.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Sugar_tr PF00083.19 KII93797.1 - 2.5e-102 342.7 13.4 2.9e-102 342.5 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII93797.1 - 1.3e-31 109.6 41.6 3.4e-27 95.0 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3180 PF11377.3 KII93797.1 - 1.3 8.8 8.8 1.8 8.4 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) BAR PF03114.13 KII93798.1 - 0.13 11.7 0.3 0.15 11.5 0.2 1.0 1 0 0 1 1 1 0 BAR domain PPR_2 PF13041.1 KII93799.1 - 1.5e-51 172.1 0.7 1.3e-10 41.0 0.0 9.4 7 2 2 9 9 9 7 PPR repeat family PPR_3 PF13812.1 KII93799.1 - 3.9e-39 129.6 7.0 3.3e-06 26.9 0.0 12.4 12 0 0 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.15 KII93799.1 - 2.8e-23 80.2 12.1 0.0015 18.3 0.0 12.4 13 1 0 13 13 13 7 PPR repeat PPR_1 PF12854.2 KII93799.1 - 1.6e-16 59.4 12.1 0.026 13.9 0.1 8.3 9 1 0 9 9 9 5 PPR repeat TPR_16 PF13432.1 KII93799.1 - 0.0027 18.3 6.7 0.75 10.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Pro_isomerase PF00160.16 KII93800.1 - 3.3e-44 150.8 0.0 5.1e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KII93800.1 - 0.0014 17.8 0.1 0.0095 15.1 0.0 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 KII93800.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain Snf7 PF03357.16 KII93801.1 - 6.4e-34 116.8 7.8 7.5e-34 116.5 5.4 1.0 1 0 0 1 1 1 1 Snf7 HAUS2 PF15003.1 KII93801.1 - 0.0088 15.1 1.2 0.012 14.7 0.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 DUF2481 PF10654.4 KII93801.1 - 1.1 8.9 5.9 0.64 9.7 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2481) Git3 PF11710.3 KII93802.1 - 3.2e-09 36.6 8.8 1.8e-08 34.2 6.1 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3 PF11710.3 KII93803.1 - 0.0013 18.3 3.1 0.0013 18.3 2.2 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KII93803.1 - 0.0017 17.5 5.6 0.024 13.7 3.9 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) IstB_IS21_ATP PF08483.6 KII93803.1 - 0.048 13.3 0.2 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal Dicty_CAR PF05462.6 KII93803.1 - 0.15 10.8 7.8 0.18 10.6 4.7 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Git3_C PF11970.3 KII93803.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.7 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term PgaD PF13994.1 KII93803.1 - 3.6 7.0 7.4 1.2 8.6 0.0 2.8 2 1 1 3 3 3 0 PgaD-like protein Git3 PF11710.3 KII93804.1 - 3.8e-07 29.8 13.7 3.8e-07 29.8 9.5 2.3 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KII93804.1 - 0.00077 18.6 7.2 0.002 17.3 4.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PP2C PF00481.16 KII93805.1 - 3.9e-37 128.0 0.0 1.8e-32 112.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KII93805.1 - 0.029 13.7 0.0 0.078 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C G_glu_transpept PF01019.16 KII93806.1 - 4.7e-147 490.5 0.0 5.3e-147 490.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Prefoldin_2 PF01920.15 KII93807.1 - 6.5e-23 80.5 15.2 8.8e-23 80.0 10.1 1.6 1 1 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 KII93807.1 - 0.0023 17.7 13.3 0.14 12.0 2.8 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KII93807.1 - 0.0036 16.9 16.9 0.014 15.0 6.9 2.0 1 1 1 2 2 2 2 IncA protein Leu_zip PF15294.1 KII93807.1 - 0.017 14.2 8.8 0.019 14.0 6.1 1.0 1 0 0 1 1 1 0 Leucine zipper NPV_P10 PF05531.7 KII93807.1 - 0.026 14.7 7.7 0.7 10.1 1.5 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF607 PF04678.8 KII93807.1 - 0.03 14.2 2.6 0.047 13.6 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TcdA_TcdB PF12919.2 KII93807.1 - 0.034 12.6 4.5 0.04 12.4 3.1 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF4201 PF13870.1 KII93807.1 - 0.063 12.7 8.9 0.46 9.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 KII93807.1 - 0.067 12.3 0.4 0.12 11.5 0.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KII93807.1 - 0.15 11.8 6.7 0.47 10.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3166 PF11365.3 KII93807.1 - 0.25 11.8 7.0 0.28 11.6 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) LLC1 PF14945.1 KII93807.1 - 0.32 11.3 2.4 0.75 10.1 0.3 2.0 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RmuC PF02646.11 KII93807.1 - 0.35 9.6 12.3 1.2 7.9 3.2 2.0 1 1 1 2 2 2 0 RmuC family YgaB PF14182.1 KII93807.1 - 0.43 10.8 12.4 0.048 13.8 2.7 2.4 2 1 0 2 2 2 0 YgaB-like protein Occludin_ELL PF07303.8 KII93807.1 - 0.44 11.2 8.9 2.4 8.9 0.9 2.2 1 1 0 2 2 2 0 Occludin homology domain Uds1 PF15456.1 KII93807.1 - 0.55 10.2 5.5 1.1 9.2 3.8 1.6 1 1 0 1 1 1 0 Up-regulated During Septation COG2 PF06148.6 KII93807.1 - 0.71 9.7 5.6 2.2 8.1 0.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.1 KII93807.1 - 0.77 9.4 9.5 3.5 7.2 1.5 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin PF02996.12 KII93807.1 - 0.91 9.1 13.6 0.28 10.8 2.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 KII93807.1 - 0.96 9.0 12.9 3.1 7.4 1.7 2.0 1 1 1 2 2 2 0 Mnd1 family Spc24 PF08286.6 KII93807.1 - 0.98 9.1 12.7 2.9 7.5 1.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 KII93807.1 - 1 8.3 15.1 0.23 10.4 4.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KII93807.1 - 1.1 9.0 15.9 1.1 9.0 3.1 2.1 2 0 0 2 2 2 0 Tropomyosin like RF-1 PF00472.15 KII93807.1 - 1.2 8.9 6.5 2.6 7.8 0.3 2.3 2 0 0 2 2 2 0 RF-1 domain Img2 PF05046.9 KII93807.1 - 1.4 9.2 3.9 2.6 8.3 0.3 2.2 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DUF972 PF06156.8 KII93807.1 - 1.4 9.2 12.9 2.6 8.4 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DASH_Dad3 PF08656.5 KII93807.1 - 1.5 8.6 7.0 4.2 7.1 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 Rho_Binding PF08912.6 KII93807.1 - 1.5 9.1 11.6 2.3 8.5 1.3 2.2 2 0 0 2 2 2 0 Rho Binding DUF1978 PF09321.5 KII93807.1 - 2 7.7 9.5 0.61 9.4 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) TBPIP PF07106.8 KII93807.1 - 2.2 7.8 14.8 2.2 7.8 2.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4510 PF14971.1 KII93807.1 - 2.3 8.3 7.4 0.32 11.1 0.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4510) Spc7 PF08317.6 KII93807.1 - 2.6 6.6 13.6 3.9 6.0 9.4 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein HAP1_N PF04849.8 KII93807.1 - 2.8 6.7 12.1 0.26 10.1 1.9 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Fib_alpha PF08702.5 KII93807.1 - 3 7.9 9.8 0.49 10.5 1.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 KII93807.1 - 3.8 6.6 16.2 1.3 8.1 3.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 KII93807.1 - 3.9 7.2 9.4 3.6 7.3 1.1 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF4200 PF13863.1 KII93807.1 - 4.7 7.1 12.7 1.3 8.9 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Macoilin PF09726.4 KII93807.1 - 4.7 5.3 11.7 8.1 4.5 8.1 1.3 1 1 0 1 1 1 0 Transmembrane protein ACCA PF03255.9 KII93807.1 - 4.7 6.7 7.7 11 5.5 0.6 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FemAB PF02388.11 KII93807.1 - 5.2 5.6 8.8 0.82 8.2 1.4 2.0 2 0 0 2 2 2 0 FemAB family Fez1 PF06818.10 KII93807.1 - 7 6.6 14.6 1.1 9.1 1.8 2.2 1 1 0 2 2 2 0 Fez1 Seryl_tRNA_N PF02403.17 KII93807.1 - 7.4 6.6 11.6 3e+02 1.4 7.9 2.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Kinetocho_Slk19 PF12709.2 KII93807.1 - 9.6 6.3 13.5 7.4 6.7 2.4 2.7 2 2 1 3 3 3 0 Central kinetochore-associated Ribosomal_S17 PF00366.15 KII93809.1 - 1.7e-16 59.9 2.6 2.2e-16 59.6 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 MFS_1 PF07690.11 KII93810.1 - 4.2e-43 147.3 42.2 2.5e-42 144.8 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII93810.1 - 7.9e-12 44.4 10.1 7.9e-12 44.4 7.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KII93810.1 - 7e-11 41.0 0.5 7e-11 41.0 0.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 KII93811.1 - 1.1e-07 31.3 9.3 0.0018 18.0 0.0 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.6 KII93811.1 - 0.00038 20.2 0.0 15 5.2 0.0 5.1 4 1 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Transglut_N PF00868.15 KII93811.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Transglutaminase family Sec39 PF08314.6 KII93812.1 - 8.6e-65 219.0 0.0 1.3e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 UPF0113 PF03657.8 KII93814.1 - 4.2e-09 36.2 0.0 5.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) NRDE-2 PF08424.5 KII93815.1 - 7.4e-51 172.9 0.7 2.5e-50 171.2 0.1 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KII93815.1 - 0.00041 20.7 20.7 0.033 14.8 0.0 7.6 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII93815.1 - 0.00071 20.1 6.9 0.0038 17.8 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat UreD PF01774.12 KII93817.1 - 3.4e-53 180.2 0.0 4e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein His_Phos_2 PF00328.17 KII93818.1 - 3.5e-40 138.3 0.0 4.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 KII93819.1 - 1.4e-24 86.5 62.7 1.8e-23 82.8 26.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M41 PF01434.13 KII93820.1 - 2.1e-71 239.8 0.0 1.2e-70 237.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 KII93820.1 - 6.6e-43 146.0 0.0 1.3e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KII93820.1 - 1.8e-12 47.3 0.0 4.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 KII93820.1 - 0.0021 18.2 0.1 0.074 13.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII93820.1 - 0.0022 18.7 0.0 0.0059 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KII93820.1 - 0.0031 16.2 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KII93820.1 - 0.0033 17.1 0.4 0.01 15.5 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KII93820.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KII93820.1 - 0.0061 16.4 0.0 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KII93820.1 - 0.01 15.7 0.1 0.11 12.4 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 KII93820.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KII93820.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KII93820.1 - 0.027 13.5 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KII93820.1 - 0.09 12.1 0.5 0.27 10.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain Chitin_bind_3 PF03067.10 KII93821.1 - 8.4e-10 39.2 1.4 1e-09 38.9 1.0 1.1 1 0 0 1 1 1 1 Chitin binding domain Cgr1 PF03879.9 KII93823.1 - 2.2e-21 76.0 26.8 2.6e-21 75.8 18.6 1.0 1 0 0 1 1 1 1 Cgr1 family RF-1 PF00472.15 KII93823.1 - 0.16 11.7 11.0 0.22 11.3 7.6 1.4 1 1 0 1 1 1 0 RF-1 domain PEARLI-4 PF05278.7 KII93823.1 - 0.47 9.7 14.6 0.61 9.4 10.1 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Macoilin PF09726.4 KII93823.1 - 0.68 8.1 14.6 0.74 8.0 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein PBP_sp32 PF07222.7 KII93823.1 - 1.4 8.0 8.0 1.6 7.8 5.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNase_H2-Ydr279 PF09468.5 KII93823.1 - 1.7 7.7 8.5 1.7 7.7 5.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) IncA PF04156.9 KII93823.1 - 2.2 7.8 6.4 2.6 7.6 4.4 1.1 1 0 0 1 1 1 0 IncA protein DDHD PF02862.12 KII93823.1 - 5.2 6.8 8.5 6.2 6.5 5.9 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KII93823.1 - 5.6 6.7 9.3 5.9 6.7 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2514 PF10721.4 KII93823.1 - 5.9 6.5 15.8 7.3 6.2 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Atg14 PF10186.4 KII93823.1 - 7.7 5.3 13.2 8.3 5.2 9.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KII93823.1 - 8.1 5.3 11.6 8.8 5.2 8.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pep3_Vps18 PF05131.9 KII93824.1 - 1.3e-44 151.1 0.0 2.6e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KII93824.1 - 5.1e-09 35.8 5.0 9.3e-05 22.0 0.0 3.2 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 KII93824.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KII93824.1 - 0.00016 21.4 4.3 0.00042 20.0 1.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KII93824.1 - 0.00062 19.4 1.1 0.00062 19.4 0.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF1664 PF07889.7 KII93824.1 - 0.0084 15.9 0.5 0.35 10.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.1 KII93824.1 - 0.051 13.6 3.6 0.067 13.2 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII93824.1 - 0.077 12.6 1.7 0.62 9.7 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KII93824.1 - 0.079 12.6 0.6 0.39 10.4 0.3 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.20 KII93824.1 - 0.56 9.9 4.8 0.15 11.7 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 KII93824.1 - 1.9 8.5 6.1 11 6.2 1.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat His_Phos_1 PF00300.17 KII93825.1 - 4.7e-29 101.5 0.0 5.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Reo_sigmaC PF04582.7 KII93826.1 - 0.0027 16.9 12.3 0.0027 16.9 8.6 6.7 2 1 5 8 8 8 3 Reovirus sigma C capsid protein Sec62 PF03839.11 KII93826.1 - 0.027 13.8 0.3 0.027 13.8 0.2 5.2 3 1 4 7 7 7 0 Translocation protein Sec62 Mito_carr PF00153.22 KII93827.1 - 1e-26 92.4 8.9 2.5e-12 46.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dehydrin PF00257.14 KII93830.1 - 0.0084 16.4 6.1 0.0093 16.3 3.6 1.4 1 1 0 1 1 1 1 Dehydrin WW PF00397.21 KII93830.1 - 0.045 13.6 0.9 0.12 12.2 0.6 1.7 1 0 0 1 1 1 0 WW domain TRAPPC-Trs85 PF12739.2 KII93831.1 - 2.6e-29 102.1 0.0 3.2e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 KII93831.1 - 0.27 8.5 0.0 0.39 7.9 0.0 1.2 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mpv17_PMP22 PF04117.7 KII93832.1 - 1.1e-12 47.4 3.2 1.7e-12 46.7 2.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4229 PF14012.1 KII93832.1 - 0.091 12.6 0.3 0.3 11.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Ribosomal_S21 PF01165.15 KII93833.1 - 0.1 12.0 0.2 0.29 10.6 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S21 PsbK PF02533.10 KII93834.1 - 0.17 11.8 1.5 0.51 10.3 1.1 1.8 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component Polyoma_coat2 PF00761.15 KII93835.1 - 4.1 6.7 5.8 6.8 6.0 4.1 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein AAA_19 PF13245.1 KII93836.1 - 0.077 12.7 3.3 0.096 12.4 2.1 1.4 1 1 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 KII93837.1 - 8e-15 54.6 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93837.1 - 0.004 16.2 0.0 0.013 14.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4369 PF14289.1 KII93838.1 - 0.025 14.6 0.0 0.063 13.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) Pkinase PF00069.20 KII93839.1 - 3.5e-16 59.1 0.0 4.2e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Helitron_like_N PF14214.1 KII93844.1 - 5.4e-16 58.8 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4428 PF14471.1 KII93844.1 - 0.03 14.0 0.6 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Ribonuc_red_sm PF00268.16 KII93845.1 - 2.4e-99 331.8 0.1 3.1e-99 331.5 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Methyltransf_23 PF13489.1 KII93850.1 - 1.6e-17 63.7 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII93850.1 - 2.2e-10 40.8 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII93850.1 - 3.7e-09 36.3 0.0 2.6e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KII93850.1 - 8.4e-07 27.6 0.0 2.3e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 KII93850.1 - 2.3e-06 27.9 0.0 8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII93850.1 - 1.8e-05 25.2 0.0 0.00012 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII93850.1 - 2.6e-05 24.5 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KII93850.1 - 3.7e-05 23.3 0.0 0.00018 21.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 KII93850.1 - 0.00021 20.5 0.0 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_8 PF05148.10 KII93850.1 - 0.00032 20.4 0.0 0.00057 19.5 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 KII93850.1 - 0.00099 18.2 0.0 0.021 13.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KII93850.1 - 0.0013 17.8 0.0 0.033 13.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KII93850.1 - 0.012 14.9 0.0 0.031 13.6 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase small domain CMAS PF02353.15 KII93850.1 - 0.013 14.6 0.0 0.072 12.1 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KII93850.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KII93850.1 - 0.03 14.3 0.0 0.092 12.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain HMG_box PF00505.14 KII93851.1 - 4.5e-07 30.0 2.3 7.8e-07 29.2 1.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII93851.1 - 5.9e-05 23.3 1.9 0.00011 22.5 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain DEAD PF00270.24 KII93853.1 - 1.7e-18 66.6 0.0 4.2e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII93853.1 - 4.8e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII93853.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KII93854.1 - 6.1e-16 58.0 0.0 1.6e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NinG PF05766.7 KII93854.1 - 0.57 9.9 5.7 2.2 7.9 0.5 2.2 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein FAM176 PF14851.1 KII93854.1 - 0.6 9.7 4.4 1.9 8.1 0.1 2.2 2 0 0 2 2 2 0 FAM176 family DUF4203 PF13886.1 KII93856.1 - 9.1e-39 133.0 28.6 1.7e-38 132.2 19.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mucin PF01456.12 KII93856.1 - 4.6 6.9 20.3 0.2 11.4 10.0 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4131 PF13567.1 KII93856.1 - 5.9 6.2 23.2 3.7 6.9 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) XRCC1_N PF01834.11 KII93856.1 - 10 5.6 7.9 0.9 8.9 1.2 2.3 3 0 0 3 3 3 0 XRCC1 N terminal domain LAG1-DNAbind PF09271.6 KII93857.1 - 6e-25 88.3 0.0 2.7e-23 82.9 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KII93857.1 - 1.3e-24 86.7 0.0 3e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.16 KII93858.1 - 8.1e-161 534.4 0.4 1e-160 534.1 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KII93858.1 - 4.3e-32 110.1 0.0 1.2e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KII93858.1 - 5.2e-05 22.2 0.6 0.00013 20.9 0.5 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KII93858.1 - 0.00078 18.4 0.0 0.013 14.4 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.10 KII93859.1 - 2.6e-05 24.5 0.0 6.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KII93859.1 - 0.035 13.2 0.2 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KII93860.1 - 5.4e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KII93860.1 - 0.04 13.0 0.2 0.065 12.3 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribul_P_3_epim PF00834.14 KII93861.1 - 8.1e-62 207.9 0.0 9.8e-62 207.6 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family 2-Hacid_dh_C PF02826.14 KII93863.1 - 5.4e-54 182.0 0.0 9.9e-54 181.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII93863.1 - 1e-08 34.7 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KII93863.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KII93863.1 - 0.017 14.4 0.0 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain PC_rep PF01851.17 KII93864.1 - 3.9e-36 121.2 22.6 1.2e-08 34.7 0.0 9.2 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KII93864.1 - 4.2e-24 84.6 0.4 6.2e-11 42.4 0.0 4.4 2 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 KII93864.1 - 2e-07 31.3 2.6 0.013 15.9 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KII93864.1 - 1.2e-06 28.1 0.6 1.6 8.9 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.15 KII93864.1 - 0.17 10.1 0.0 0.36 9.0 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_PBS PF03130.11 KII93864.1 - 0.77 10.4 3.3 1.8e+02 3.0 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat COX6A PF02046.10 KII93865.1 - 2.2e-26 92.0 0.2 2.6e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Arm PF00514.18 KII93866.1 - 3e-91 296.5 14.3 6.2e-13 48.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KII93866.1 - 7e-23 80.4 2.2 1.9e-08 34.5 0.0 5.3 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.1 KII93866.1 - 2.2e-21 75.9 0.1 2.3e-07 30.9 0.0 5.5 1 1 4 5 5 5 5 HEAT repeats IBB PF01749.15 KII93866.1 - 3e-21 75.3 3.7 4.7e-21 74.7 2.6 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KII93866.1 - 1.7e-16 58.7 0.3 4.7e-05 23.1 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Arm_2 PF04826.8 KII93866.1 - 1e-06 28.0 0.0 0.04 13.0 0.0 4.1 2 1 1 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 KII93866.1 - 2.2e-06 26.2 0.0 0.00035 19.0 0.0 2.8 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 KII93866.1 - 1.4e-05 24.9 2.2 0.072 13.0 0.0 4.5 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 KII93866.1 - 0.00045 20.4 0.7 0.57 10.8 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 KII93866.1 - 0.00049 20.0 0.1 0.61 10.0 0.0 4.3 3 2 0 4 4 4 1 V-ATPase subunit H Mo25 PF08569.6 KII93866.1 - 0.046 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Mo25-like LSM PF01423.17 KII93867.1 - 1.1e-20 72.9 0.1 1.3e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain UPF0565 PF10561.4 KII93867.1 - 0.12 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Homeobox PF00046.24 KII93869.1 - 1.3e-08 34.3 0.1 2.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain Ribosomal_S16 PF00886.14 KII93870.1 - 8.4e-20 70.2 0.0 1.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.14 KII93871.1 - 2.6e-15 55.8 0.0 4.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.2 KII93871.1 - 1.3e-13 51.0 0.5 2.2e-13 50.3 0.1 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KII93871.1 - 8.8e-13 48.0 0.2 2.4e-12 46.6 0.1 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KII93871.1 - 3e-12 45.6 1.0 2.1e-10 39.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KII93871.1 - 2.9e-11 43.5 1.4 9.3e-06 26.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII93871.1 - 2.1e-07 30.5 0.1 1.7e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat CoA_binding PF02629.14 KII93872.1 - 4.1e-28 97.7 0.2 4.1e-28 97.7 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KII93872.1 - 1.9e-24 85.9 0.1 3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KII93872.1 - 1.7e-08 34.1 0.0 5.3e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KII93872.1 - 2.5e-05 24.3 0.3 9.6e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 KII93872.1 - 0.0032 17.9 0.0 0.01 16.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Xpo1 PF08389.7 KII93873.1 - 3.4e-22 78.9 0.0 1.3e-20 73.8 0.0 3.2 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KII93873.1 - 9.2e-08 31.8 0.0 3.5e-06 26.8 0.0 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 KII93873.1 - 0.0017 18.2 0.1 0.29 11.3 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat DehI PF10778.4 KII93873.1 - 0.065 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI WVELL PF14043.1 KII93873.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 WVELL protein Septin PF00735.13 KII93874.1 - 2.1e-122 407.5 0.1 2.1e-122 407.5 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KII93874.1 - 9.6e-08 31.9 0.0 2.1e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KII93874.1 - 5.8e-06 25.5 0.1 2e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KII93874.1 - 1.6e-05 24.4 2.0 0.00038 19.9 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KII93874.1 - 0.00014 22.0 0.1 0.0013 18.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AIG1 PF04548.11 KII93874.1 - 0.00069 18.7 0.7 0.0015 17.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Ras PF00071.17 KII93874.1 - 0.0014 17.9 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.22 KII93874.1 - 0.0016 18.7 5.4 0.014 15.6 0.4 2.6 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 KII93874.1 - 0.0036 17.7 0.0 0.094 13.2 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KII93874.1 - 0.0053 16.2 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 KII93874.1 - 0.0088 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KII93874.1 - 0.015 15.1 4.7 1.2 8.9 0.1 3.3 2 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 KII93874.1 - 0.026 14.0 0.2 4 6.9 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KII93874.1 - 0.027 14.4 0.1 0.082 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 KII93874.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KII93874.1 - 0.054 12.9 0.2 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 KII93874.1 - 0.083 12.5 1.4 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KII93874.1 - 0.11 12.1 1.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KII93874.1 - 0.12 11.8 0.1 6.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Exonuc_VII_L PF02601.10 KII93874.1 - 0.17 11.0 2.3 0.36 9.9 1.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit CN_hydrolase PF00795.17 KII93875.1 - 2.5e-33 115.0 0.0 3.1e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.4 KII93876.1 - 6.2e-31 107.1 0.0 1.1e-30 106.2 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF2606 PF10794.4 KII93876.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF866 PF05907.8 KII93877.1 - 8.3e-49 165.1 0.0 9.1e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 KII93877.1 - 0.019 14.5 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 KII93877.1 - 0.63 10.3 2.8 1.9 8.8 0.1 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 KII93877.1 - 0.95 9.3 6.3 11 5.8 2.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Phostensin_N PF13916.1 KII93878.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal FdsD PF11390.3 KII93879.1 - 0.16 12.0 0.8 0.35 11.0 0.5 1.6 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Pkinase PF00069.20 KII93880.1 - 2.6e-67 226.7 0.0 3.7e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93880.1 - 7.7e-44 149.7 0.0 1.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93880.1 - 2.3e-08 33.3 0.0 5.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.1 KII93880.1 - 0.00012 21.9 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kdo PF06293.9 KII93880.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KII93880.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CLTH PF10607.4 KII93881.1 - 5.1e-36 123.5 0.0 6e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KII93881.1 - 5e-06 26.0 0.2 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 LisH FMO-like PF00743.14 KII93882.1 - 4.4e-32 110.9 0.0 1.1e-22 79.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KII93882.1 - 1.9e-19 70.5 0.0 3.6e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KII93882.1 - 2.6e-08 33.7 1.1 1.3e-06 28.2 0.2 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KII93882.1 - 1.7e-07 30.5 0.4 2.2e-05 23.5 0.1 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KII93882.1 - 4.2e-07 30.0 0.0 0.0031 17.4 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KII93882.1 - 1e-05 24.7 0.0 0.026 13.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 KII93882.1 - 1.1e-05 25.4 0.1 0.0028 17.6 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KII93882.1 - 0.0075 15.2 0.3 2.3 7.0 0.0 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KII93882.1 - 0.037 13.7 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KII93882.1 - 0.069 13.2 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF498 PF04430.9 KII93882.1 - 0.096 12.2 0.0 6.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) Malic_M PF03949.10 KII93882.1 - 0.13 11.8 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain HI0933_like PF03486.9 KII93882.1 - 0.18 10.2 0.1 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KII93882.1 - 1.2 7.9 2.2 1.4 7.6 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Rrp15p PF07890.7 KII93883.1 - 4.8e-22 78.4 3.9 4.8e-22 78.4 2.7 2.1 1 1 1 2 2 2 1 Rrp15p CDC45 PF02724.9 KII93883.1 - 2.5 6.0 9.3 3.4 5.6 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KII93883.1 - 3.2 7.2 9.2 6.6 6.2 3.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DIL PF01843.14 KII93884.1 - 5.3e-22 77.6 0.4 1.5e-21 76.2 0.2 1.8 2 0 0 2 2 2 1 DIL domain Ank PF00023.25 KII93884.1 - 1.2e-12 46.9 0.6 7.5e-05 22.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KII93884.1 - 4.8e-12 46.0 0.0 3e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII93884.1 - 2.3e-09 37.5 0.1 1.1e-06 28.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII93884.1 - 5.3e-09 36.0 0.3 1.5e-05 25.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII93884.1 - 1.1e-06 28.2 0.4 0.0014 18.6 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat FAST_1 PF06743.10 KII93884.1 - 0.1 12.3 0.2 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 SnoaL PF07366.7 KII93885.1 - 1e-07 31.5 0.0 1.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KII93885.1 - 5.5e-05 23.5 0.1 9.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Rhomboid PF01694.17 KII93886.1 - 8e-33 113.5 16.1 1e-32 113.1 9.7 2.0 1 1 1 2 2 2 1 Rhomboid family DUF3094 PF11293.3 KII93886.1 - 0.0084 15.5 0.3 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3094) DUF4203 PF13886.1 KII93886.1 - 5.3 6.4 16.5 0.21 11.0 7.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) Cas1_AcylT PF07779.7 KII93887.1 - 4.4e-152 506.9 19.0 8.2e-151 502.7 13.2 2.0 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KII93887.1 - 3.8e-27 95.7 0.0 6.5e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p adh_short_C2 PF13561.1 KII93888.1 - 7.1e-32 111.0 1.4 8.4e-32 110.8 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KII93888.1 - 7.5e-27 94.2 0.4 1.1e-26 93.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII93888.1 - 5.1e-11 42.5 0.1 8.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 KR domain OCC1 PF15506.1 KII93888.1 - 0.015 15.1 1.7 0.41 10.5 0.9 2.8 2 0 0 2 2 2 0 OCC1 family F420_oxidored PF03807.12 KII93888.1 - 0.018 15.4 0.1 0.05 14.0 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1998 PF09369.5 KII93888.1 - 0.025 15.1 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1998) PEP_mutase PF13714.1 KII93888.1 - 0.038 13.2 0.1 0.075 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase 3HCDH_N PF02737.13 KII93888.1 - 0.04 13.5 0.2 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 KII93890.1 - 2.9e-09 36.8 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII93890.1 - 6.3e-08 33.0 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII93890.1 - 1.1e-06 29.1 0.0 1.8e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII93890.1 - 6e-06 25.9 0.0 2.1e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII93890.1 - 1.1e-05 25.7 0.0 2.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KII93890.1 - 0.0092 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KII93890.1 - 0.013 15.5 0.0 0.043 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KII93890.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.1 KII93891.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 PPR repeat family RNase_T PF00929.19 KII93892.1 - 3.6e-09 37.1 0.0 4.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF3025 PF11227.3 KII93892.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Mito_carr PF00153.22 KII93893.1 - 3.5e-52 174.0 3.6 1.1e-17 63.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2793 PF10983.3 KII93893.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) RINGv PF12906.2 KII93894.1 - 9.1e-14 51.2 4.5 1.4e-13 50.6 3.2 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KII93894.1 - 1.7e-05 24.5 6.7 2.6e-05 23.9 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII93894.1 - 0.031 13.9 4.1 0.05 13.2 2.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1705 PF08019.7 KII93894.1 - 0.04 13.4 1.1 0.89 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) zf-C3HC4 PF00097.20 KII93894.1 - 0.12 12.0 2.6 0.48 10.1 1.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII93894.1 - 0.35 10.4 5.4 0.66 9.5 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KII93894.1 - 0.4 10.3 4.5 0.64 9.7 3.1 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 KII93894.1 - 0.68 10.0 6.3 1.4 9.0 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_C PF03177.9 KII93895.1 - 1e-79 268.6 0.0 1.4e-79 268.1 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KII93895.1 - 3.2e-58 197.4 0.0 6e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like NAD_binding_6 PF08030.7 KII93897.1 - 1.2e-23 83.6 0.0 2.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KII93897.1 - 6.8e-21 74.1 0.0 1.6e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KII93897.1 - 2.6e-15 56.6 10.6 6.4e-15 55.3 7.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KII93897.1 - 0.00014 21.9 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KII93897.1 - 0.00053 20.5 0.0 0.043 14.3 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain HORMA PF02301.13 KII93898.1 - 1.6e-34 119.2 0.1 1.9e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KII93898.1 - 0.0011 18.4 0.1 0.0053 16.2 0.1 1.9 1 1 0 1 1 1 1 Autophagy-related protein 13 Acetyltransf_1 PF00583.19 KII93899.1 - 1.7e-10 40.8 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KII93899.1 - 2.4e-06 27.7 0.0 4.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII93899.1 - 2.6e-05 23.8 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KII93899.1 - 2.7e-05 24.2 0.0 0.0001 22.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII93899.1 - 3.6e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII93899.1 - 3.6e-05 23.7 0.0 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII93899.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KII93899.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Meth_synt_2 PF01717.13 KII93901.1 - 3.1e-18 65.8 0.0 8.8e-17 61.0 0.0 2.6 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KII93901.1 - 1.5e-06 27.6 0.0 0.0057 15.9 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.13 KII93902.1 - 5.5e-67 224.7 6.9 5.5e-67 224.7 4.8 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e Pal1 PF08316.6 KII93903.1 - 9.2e-16 58.5 0.9 9.2e-16 58.5 0.6 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein FA_desaturase PF00487.19 KII93904.1 - 7.9e-35 120.5 24.2 1.1e-34 120.0 16.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KII93904.1 - 9.8e-11 41.3 0.0 2.5e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HhH-GPD PF00730.20 KII93905.1 - 5.8e-22 78.0 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KII93905.1 - 2.4e-07 30.0 0.0 6.1e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF4507 PF14964.1 KII93905.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) His_biosynth PF00977.16 KII93906.1 - 1e-43 149.2 0.3 5.4e-43 146.8 0.2 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KII93906.1 - 5.4e-24 84.7 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KII93906.1 - 6.8e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KII93906.1 - 1.7e-07 31.0 0.0 2.2e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 KII93906.1 - 0.025 14.0 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 ThiG PF05690.9 KII93906.1 - 0.063 12.3 0.4 0.1 11.6 0.3 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Peptidase_S51 PF03575.12 KII93906.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 2-Hacid_dh_C PF02826.14 KII93907.1 - 2.5e-51 173.3 0.0 6.4e-51 172.0 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII93907.1 - 1.4e-32 111.9 0.0 1.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KII93907.1 - 0.0046 16.8 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2597 PF10772.4 KII93907.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) AdoHcyase_NAD PF00670.16 KII93907.1 - 0.036 13.9 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HYLS1_C PF15311.1 KII93908.1 - 0.12 12.6 1.6 0.17 12.1 1.1 1.2 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Abhydrolase_5 PF12695.2 KII93909.1 - 1.4e-22 80.0 0.0 2.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII93909.1 - 6.5e-19 68.7 0.0 3.2e-17 63.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KII93909.1 - 4.4e-08 33.0 0.2 0.00012 21.8 0.0 2.4 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KII93909.1 - 2.3e-07 30.2 0.0 7e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KII93909.1 - 1.1e-06 28.2 0.1 0.015 14.7 0.1 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KII93909.1 - 5e-06 26.2 0.0 0.00043 19.9 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 KII93909.1 - 1.1e-05 24.1 0.0 0.011 14.2 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 KII93909.1 - 5.5e-05 22.5 0.0 0.06 12.6 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KII93909.1 - 0.00041 19.8 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.8 KII93909.1 - 0.0014 18.2 0.0 0.0035 16.9 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 KII93909.1 - 0.003 17.0 0.0 0.0071 15.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 KII93909.1 - 0.0059 16.0 0.1 0.0088 15.4 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KII93909.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.6 KII93909.1 - 0.054 12.0 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF818 PF05677.7 KII93909.1 - 0.079 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.7 KII93909.1 - 0.088 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Tannase PF07519.6 KII93909.1 - 0.16 10.6 0.0 6.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Tannase and feruloyl esterase Transp_cyt_pur PF02133.10 KII93910.1 - 2e-82 277.1 32.2 2.4e-82 276.8 22.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NDUF_B12 PF08122.7 KII93910.1 - 1.4 8.7 5.7 14 5.4 0.1 4.3 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family DIOX_N PF14226.1 KII93911.1 - 2.4e-25 89.3 0.0 5.1e-25 88.2 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII93911.1 - 3.6e-19 68.8 0.0 5.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.16 KII93912.1 - 3.4e-21 75.6 0.0 4.4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KII93912.1 - 3.8e-08 32.3 0.0 5.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF917 PF06032.7 KII93913.1 - 1.6e-108 362.4 0.0 2.8e-108 361.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KII93913.1 - 4.2e-46 157.3 6.5 1.4e-45 155.6 2.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KII93913.1 - 2.7e-28 98.6 0.2 1.5e-27 96.2 0.0 2.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KII93913.1 - 2.2e-05 22.9 0.3 0.00083 17.7 0.1 2.2 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 KII93913.1 - 5.5e-05 22.6 0.1 0.0026 17.1 0.0 2.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Aldo_ket_red PF00248.16 KII93914.1 - 8.4e-50 169.1 0.0 1.1e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DEAD PF00270.24 KII93915.1 - 7.3e-17 61.3 0.0 2e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII93915.1 - 1.4e-16 60.0 0.0 6.2e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF772 PF05598.6 KII93917.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 2 0 0 2 2 2 0 Transposase domain (DUF772) DUF2146 PF10220.4 KII93917.1 - 9.4 4.0 9.3 12 3.7 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) WD40 PF00400.27 KII93918.1 - 9.4e-61 199.6 15.6 6.1e-11 41.7 0.6 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KII93918.1 - 4.1e-31 107.9 0.0 1.1e-30 106.5 0.0 1.6 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 KII93918.1 - 0.0004 20.0 0.6 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 LisH eIF2A PF08662.6 KII93918.1 - 0.022 14.4 0.0 0.3 10.7 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KII93918.1 - 1.2 7.1 3.6 20 3.1 0.0 3.2 2 2 1 3 3 3 0 Nucleoporin Nup120/160 CRAL_TRIO PF00650.15 KII93920.1 - 4.1e-30 104.3 0.0 5.3e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KII93920.1 - 3.2e-10 39.9 0.2 7.5e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ribosomal_L4 PF00573.17 KII93921.1 - 4.5e-56 189.2 2.4 1.6e-55 187.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 KII93922.1 - 3.8e-40 136.9 0.4 4.3e-40 136.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Tim17 PF02466.14 KII93925.1 - 1.5e-12 47.6 9.4 2.1e-12 47.1 6.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.27 KII93926.1 - 6.1e-17 60.7 4.0 5.7e-07 29.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat SUR7 PF06687.7 KII93928.1 - 6.2e-21 74.9 10.7 7.6e-21 74.6 7.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KII93928.1 - 2.4e-05 24.1 6.8 2.4e-05 24.1 4.7 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF566 PF04484.7 KII93929.1 - 2.3 7.6 11.3 2.7 7.4 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Glyco_transf_28 PF03033.15 KII93930.1 - 2.2e-25 89.0 0.0 4.1e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KII93930.1 - 3.4e-19 68.1 0.4 4e-10 39.0 0.1 3.5 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 KII93930.1 - 4.7e-12 46.0 1.2 4.8e-11 42.7 0.2 3.0 2 0 0 2 2 2 1 PH domain PH_6 PF15406.1 KII93930.1 - 7.7e-05 22.7 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KII93930.1 - 0.00012 22.3 0.9 0.005 17.0 0.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 KII93930.1 - 0.00022 19.9 0.0 0.00045 18.8 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 KII93930.1 - 0.0044 17.0 0.1 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF693 PF05113.8 KII93930.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) DIOX_N PF14226.1 KII93931.1 - 0.00079 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII93931.1 - 0.0039 17.4 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 KII93933.1 - 1.9e-27 96.6 0.0 2.3e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII93933.1 - 6.2e-14 52.1 0.0 7.1e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII93933.1 - 3.4e-07 30.1 0.0 1.5e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KII93933.1 - 0.00031 20.2 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 KII93933.1 - 0.0098 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KII93933.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 KII93933.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KII93933.1 - 0.088 12.0 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pneumo_M2 PF07380.6 KII93933.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Pneumovirus M2 protein UPF0261 PF06792.6 KII93934.1 - 0.057 11.8 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) DUF2431 PF10354.4 KII93935.1 - 5.8e-43 146.7 0.0 2.9e-42 144.4 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF2431) Cut8_N PF14482.1 KII93935.1 - 0.025 14.5 0.2 0.078 12.9 0.2 1.9 1 0 0 1 1 1 0 Cut8 proteasome-binding domain RAMP4 PF06624.7 KII93936.1 - 1.3e-05 24.6 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 ROKNT PF08067.6 KII93936.1 - 0.049 13.4 0.9 0.053 13.3 0.1 1.5 2 0 0 2 2 2 0 ROKNT (NUC014) domain Lectin_N PF03954.9 KII93936.1 - 0.074 12.4 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain WD40 PF00400.27 KII93937.1 - 1.2e-32 110.5 14.5 2.3e-09 36.7 0.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KII93937.1 - 2.9e-30 103.9 0.5 6.4e-30 102.8 0.4 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3312 PF11768.3 KII93937.1 - 0.16 10.1 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) ATP-synt_E PF05680.7 KII93938.1 - 2.5e-19 69.0 0.1 2.6e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain FliS PF02561.9 KII93938.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FliS GFA PF04828.9 KII93939.1 - 1.3e-09 37.9 0.9 1.9e-09 37.3 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-BED PF02892.10 KII93939.1 - 0.19 11.4 0.2 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger YL1 PF05764.8 KII93941.1 - 0.23 11.0 8.1 0.34 10.4 5.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Dopey_N PF04118.9 KII93942.1 - 3e-110 367.8 2.0 8.1e-110 366.4 0.0 2.6 3 0 0 3 3 3 1 Dopey, N-terminal GBP_repeat PF02526.9 KII93942.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 Glycophorin-binding protein EF-hand_6 PF13405.1 KII93943.1 - 2.3e-10 39.4 0.3 5.1e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KII93943.1 - 1.4e-07 30.5 0.1 0.00015 20.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KII93943.1 - 4.6e-07 29.8 0.7 1.1e-06 28.6 0.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KII93943.1 - 3.6e-06 25.8 0.3 0.0005 19.1 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KII93943.1 - 0.0099 15.4 0.8 0.19 11.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KII93943.1 - 0.028 14.4 0.9 0.65 10.0 0.6 2.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ABC2_membrane PF01061.19 KII93944.1 - 1.9e-72 242.8 49.3 5.7e-38 130.1 11.8 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KII93944.1 - 1.1e-32 113.1 0.0 6.8e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KII93944.1 - 2.6e-23 81.6 0.3 5.1e-17 61.4 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter cobW PF02492.14 KII93944.1 - 8.7e-07 28.5 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KII93944.1 - 1.1e-06 28.2 0.0 0.014 14.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KII93944.1 - 1.3e-06 28.5 0.1 0.069 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KII93944.1 - 3.4e-06 27.0 0.1 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 KII93944.1 - 5.1e-05 22.7 0.2 0.038 13.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 KII93944.1 - 6.6e-05 22.8 0.0 0.31 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KII93944.1 - 0.00041 21.1 0.0 0.61 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KII93944.1 - 0.00063 19.7 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KII93944.1 - 0.0036 17.5 0.0 0.72 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII93944.1 - 0.0063 16.5 0.3 1.1 9.2 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KII93944.1 - 0.0063 15.7 0.0 0.054 12.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KII93944.1 - 0.0097 15.4 0.7 4.1 6.8 0.0 2.8 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KII93944.1 - 0.01 15.2 0.1 0.17 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KII93944.1 - 0.048 13.4 0.5 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 KII93944.1 - 0.078 12.6 0.5 3 7.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KII93944.1 - 0.085 12.0 2.2 2.1 7.5 0.0 3.7 4 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII93944.1 - 0.087 12.7 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KII93944.1 - 0.12 12.5 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KII93944.1 - 0.24 11.3 0.1 5.1 7.0 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase Prefoldin_2 PF01920.15 KII93945.1 - 2.3e-14 53.0 6.6 2.7e-14 52.7 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit MYCBPAP PF14646.1 KII93945.1 - 0.025 13.2 1.6 0.028 13.1 1.1 1.3 1 1 0 1 1 1 0 MYCBP-associated protein family DUF793 PF05633.6 KII93945.1 - 0.049 12.3 1.4 0.058 12.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) CorA PF01544.13 KII93945.1 - 0.072 12.1 4.5 1.1 8.1 0.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3391 PF11871.3 KII93945.1 - 0.18 12.0 2.8 0.34 11.1 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Cytochrom_B562 PF07361.6 KII93945.1 - 0.21 11.9 4.5 5.1 7.5 0.5 2.1 2 0 0 2 2 2 0 Cytochrome b562 DivIVA PF05103.8 KII93945.1 - 0.23 11.5 5.7 5.2 7.1 1.2 2.1 2 0 0 2 2 2 0 DivIVA protein Tropomyosin_1 PF12718.2 KII93945.1 - 0.34 10.7 7.6 0.085 12.7 2.5 1.8 2 0 0 2 2 2 0 Tropomyosin like RasGAP_C PF03836.10 KII93945.1 - 0.35 10.5 5.6 0.18 11.4 0.6 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF3552 PF12072.3 KII93945.1 - 0.37 9.9 7.7 0.67 9.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.3 KII93945.1 - 0.37 10.6 8.6 0.052 13.3 3.0 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phlebovirus_NSM PF07246.6 KII93945.1 - 0.52 9.4 4.0 0.41 9.7 0.3 1.9 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FliD_C PF07195.7 KII93945.1 - 0.52 9.5 5.3 0.66 9.2 1.3 2.0 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Seryl_tRNA_N PF02403.17 KII93945.1 - 0.73 9.8 7.9 2.4 8.1 5.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 KII93945.1 - 0.86 9.5 11.4 1.4 8.8 7.9 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YlqD PF11068.3 KII93945.1 - 1.3 9.0 9.5 6 6.9 0.5 2.1 2 0 0 2 2 2 0 YlqD protein DivIC PF04977.10 KII93945.1 - 4.2 6.9 9.6 0.27 10.7 2.0 2.1 2 0 0 2 2 2 0 Septum formation initiator Calreticulin PF00262.13 KII93946.1 - 3.1e-150 499.9 8.5 4.6e-150 499.3 5.9 1.3 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.22 KII93946.1 - 9.4e-43 145.8 0.0 1.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KII93946.1 - 7.7e-26 90.0 0.0 1.8e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KII93946.1 - 9.5e-21 73.4 0.0 3e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KII93946.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII93946.1 - 4e-06 26.7 0.1 7.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 KII93946.1 - 6.5e-06 25.9 0.0 3.6e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 KII93946.1 - 7.6e-05 23.1 0.1 0.00018 21.9 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KII93946.1 - 0.0025 17.0 0.1 0.0054 15.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KII93946.1 - 0.0031 17.3 0.6 2.7 7.8 0.1 3.1 2 1 0 3 3 3 2 Dynamin family polyprenyl_synt PF00348.12 KII93947.1 - 3.3e-51 173.6 0.0 3.2e-47 160.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Pkinase PF00069.20 KII93950.1 - 3.2e-37 128.1 0.0 3.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93950.1 - 2e-13 49.9 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII93950.1 - 7.2e-05 22.6 0.0 0.0071 16.0 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII93950.1 - 0.046 12.5 0.1 0.066 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.15 KII93952.1 - 2.9e-114 382.2 0.0 3.9e-114 381.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KII93952.1 - 8.5e-59 197.7 1.1 2.1e-58 196.4 0.7 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KII93952.1 - 1.3e-13 51.0 0.6 0.0029 17.8 0.0 6.6 3 2 4 7 7 7 3 HEAT repeats HEAT PF02985.17 KII93952.1 - 0.013 15.5 8.0 8.3 6.7 0.1 6.5 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.2 KII93952.1 - 0.43 10.4 5.5 3.6 7.3 0.1 3.6 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Fumble PF03630.9 KII93953.1 - 1.9e-118 395.2 0.0 8.6e-89 297.7 0.1 2.6 2 1 0 2 2 2 2 Fumble Homeobox PF00046.24 KII93954.1 - 2.4e-44 148.7 10.2 9.2e-17 60.4 0.3 3.4 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 KII93954.1 - 3.9e-17 61.6 2.2 3.7e-06 26.5 0.1 3.7 3 0 0 3 3 3 3 Homeobox KN domain HTH_3 PF01381.17 KII93954.1 - 0.00069 19.4 0.8 0.74 9.7 0.1 3.0 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.3 KII93954.1 - 0.036 13.1 0.1 19 4.4 0.0 3.3 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Elongin_A PF06881.6 KII93954.1 - 9.4 6.6 8.3 10 6.5 1.3 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PhzC-PhzF PF02567.11 KII93955.1 - 2.1e-42 145.2 0.4 2.9e-42 144.8 0.3 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Metallophos PF00149.23 KII93956.1 - 7e-07 28.8 1.7 2.2e-06 27.2 1.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII93956.1 - 0.0026 17.6 0.0 0.0082 15.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 KII93957.1 - 1.7e-39 135.5 0.0 2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93957.1 - 3e-15 56.0 0.0 3.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII93957.1 - 9.4e-06 25.5 0.0 0.0015 18.2 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KII93957.1 - 0.017 13.9 0.1 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Chitin_synth_1 PF01644.12 KII93958.1 - 5.5e-77 257.1 0.4 8.5e-77 256.5 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KII93958.1 - 1.6e-24 85.4 0.1 4.3e-24 83.9 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KII93958.1 - 3.7e-23 81.7 0.0 5.4e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KII93958.1 - 8e-09 35.6 0.0 2e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KII93958.1 - 6.6e-08 32.4 0.2 6.6e-08 32.4 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Fibrinogen_aC PF12160.3 KII93958.1 - 0.063 12.7 0.4 0.16 11.4 0.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain cNMP_binding PF00027.24 KII93959.1 - 1.3e-40 137.0 0.0 5.5e-19 67.7 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 KII93959.1 - 3.7e-19 69.4 2.8 2.3e-12 47.2 0.7 2.8 2 0 0 2 2 2 2 Patatin-like phospholipase IL13 PF03487.8 KII93959.1 - 0.053 13.2 0.7 0.16 11.6 0.5 1.8 1 0 0 1 1 1 0 Interleukin-13 YABBY PF04690.8 KII93960.1 - 5.7e-09 36.4 0.6 6.7e-09 36.2 0.4 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.14 KII93960.1 - 0.00039 20.6 3.5 0.00055 20.1 2.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII93960.1 - 0.0016 18.7 4.1 0.0022 18.3 2.7 1.4 1 1 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 KII93960.1 - 0.0023 18.1 3.8 0.0026 17.9 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) LRR_6 PF13516.1 KII93961.1 - 5.4e-07 29.0 13.9 0.34 11.1 0.0 7.9 8 0 0 8 8 8 2 Leucine Rich repeat F-box-like PF12937.2 KII93961.1 - 0.00017 21.2 0.0 0.00045 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII93961.1 - 0.00056 19.4 3.5 11 5.7 0.6 5.9 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII93961.1 - 0.0012 18.5 8.3 2 8.7 0.1 6.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 KII93961.1 - 2.5 8.6 12.2 41 5.0 0.1 7.3 9 0 0 9 9 9 0 Leucine rich repeat Sas10_Utp3 PF04000.10 KII93962.1 - 1.6e-15 57.0 1.1 1.8e-15 56.8 0.1 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Ashwin PF15323.1 KII93962.1 - 2.1 8.2 9.7 2.9 7.8 5.4 1.9 2 0 0 2 2 2 0 Developmental protein SF3b10 PF07189.6 KII93963.1 - 1.1e-32 111.6 0.0 1.4e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_11 PF08241.7 KII93964.1 - 5.6e-13 49.1 0.0 7.9e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII93964.1 - 5.9e-10 39.0 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII93964.1 - 7.9e-10 39.3 0.0 2.2e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII93964.1 - 9.3e-09 35.5 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII93964.1 - 2.9e-08 34.0 0.0 1.1e-07 32.2 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII93964.1 - 1.1e-05 24.7 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KII93964.1 - 3.1e-05 23.6 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII93964.1 - 0.00059 19.8 0.0 0.0034 17.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KII93964.1 - 0.0024 17.9 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 KII93964.1 - 0.29 10.2 0.0 0.49 9.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB WLM PF08325.5 KII93965.1 - 1e-47 162.4 0.0 1.6e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KII93965.1 - 5.5e-06 25.3 11.2 1.9e-05 23.6 0.6 3.2 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KII93965.1 - 0.004 16.9 0.1 0.0088 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 KII93965.1 - 0.052 13.3 7.1 0.11 12.3 4.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-UBP PF02148.14 KII93965.1 - 1.3 9.2 5.2 62 3.8 3.6 2.5 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Rubredoxin PF00301.15 KII93965.1 - 2.5 8.0 10.4 2.5 8.0 0.3 3.4 2 1 1 3 3 3 0 Rubredoxin RVT_1 PF00078.22 KII93966.1 - 1.5e-05 24.4 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 KII93967.1 - 1.1e-10 41.1 0.0 1.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KII93967.1 - 2.3e-05 24.4 0.1 2.8e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_16 PF10294.4 KII93969.1 - 1.1e-19 70.5 0.0 1.5e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII93969.1 - 5e-06 27.0 0.0 9.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII93969.1 - 0.00046 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KII93969.1 - 0.00067 19.2 0.0 0.00094 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII93969.1 - 0.042 13.8 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Bot1p PF12298.3 KII93970.1 - 1.7e-24 86.6 0.0 2.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MFS_1 PF07690.11 KII93971.1 - 3.4e-20 72.0 17.7 5.6e-20 71.3 12.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF106 PF01956.11 KII93971.1 - 0.89 9.0 4.7 5.1 6.5 1.4 2.8 2 1 0 2 2 2 0 Integral membrane protein DUF106 Cpn60_TCP1 PF00118.19 KII93972.1 - 9.9e-141 469.6 0.6 1.1e-140 469.4 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HIRAN PF08797.6 KII93973.1 - 5.2e-15 55.2 0.0 8e-14 51.4 0.0 2.3 2 0 0 2 2 2 1 HIRAN domain YL1 PF05764.8 KII93974.1 - 0.1 12.1 10.0 0.22 11.0 6.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein KBP_C PF12309.3 KII93974.1 - 1.3 7.9 9.1 0.062 12.2 0.4 2.5 2 1 1 3 3 3 0 KIF-1 binding protein C terminal SNF2_N PF00176.18 KII93978.1 - 1.5e-63 214.4 0.0 2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII93978.1 - 8.6e-13 47.9 0.0 2.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII93978.1 - 3.6e-08 33.0 0.0 7.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KII93978.1 - 8.3e-07 28.5 13.5 1.7e-06 27.5 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KII93978.1 - 2.3e-06 27.5 0.0 6.5e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 KII93978.1 - 2.5e-06 27.4 14.4 2.5e-06 27.4 10.0 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII93978.1 - 2.9e-05 23.7 12.8 7.5e-05 22.4 8.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII93978.1 - 0.0002 20.9 12.0 0.00035 20.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KII93978.1 - 0.0082 16.0 12.6 0.016 15.0 8.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Patched PF02460.13 KII93978.1 - 0.012 13.5 0.0 0.018 12.9 0.0 1.2 1 0 0 1 1 1 0 Patched family zf-RING_5 PF14634.1 KII93978.1 - 0.047 13.4 11.6 0.12 12.1 8.1 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Helicase_C_4 PF13871.1 KII93978.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Helicase_C-like zf-Nse PF11789.3 KII93978.1 - 0.75 9.3 5.6 1.6 8.2 3.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KII93978.1 - 1.1 8.8 6.7 1.8 8.1 4.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ADH_zinc_N PF00107.21 KII93980.1 - 3.8e-10 39.4 0.0 7.9e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII93980.1 - 1.6e-08 34.2 0.3 1.2e-06 28.2 0.1 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII93980.1 - 0.021 15.6 0.0 0.094 13.6 0.0 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KII93981.1 - 2.3e-23 82.8 0.1 3.3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KII93981.1 - 5.1e-08 33.0 0.0 1.3e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KII93981.1 - 1.4e-05 25.4 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KII93981.1 - 3.8e-05 23.8 0.0 8.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 KII93981.1 - 0.00014 20.7 0.0 0.00027 19.7 0.0 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.14 KII93981.1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KII93981.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.11 KII93981.1 - 0.06 13.7 0.1 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Pkinase PF00069.20 KII93982.1 - 1.5e-38 132.4 0.0 2.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII93982.1 - 1.6e-27 96.1 0.0 2.2e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII93982.1 - 0.062 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ctr PF04145.10 KII93983.1 - 1.8e-05 24.8 1.9 1.8e-05 24.8 1.3 2.3 1 1 1 2 2 2 1 Ctr copper transporter family FA_desaturase PF00487.19 KII93983.1 - 0.00091 18.7 1.2 0.0012 18.3 0.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Pex24p PF06398.6 KII93983.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Exo5 PF09810.4 KII93984.1 - 3.4e-58 197.3 0.0 8.8e-49 166.4 0.0 2.7 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.15 KII93984.1 - 0.00029 20.1 3.2 0.52 10.0 0.2 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif Shisa PF13908.1 KII93987.1 - 8.3 6.5 18.0 0.82 9.8 1.3 3.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Sin3_corepress PF08295.7 KII93988.1 - 1.5e-34 117.7 0.0 3.8e-34 116.4 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KII93988.1 - 7.4e-33 111.9 5.2 4.9e-13 48.4 0.8 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat GBP_C PF02841.9 KII93988.1 - 0.0045 16.2 0.4 0.0081 15.3 0.3 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain SCF PF02404.10 KII93989.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor F-box-like PF12937.2 KII93990.1 - 1.2e-07 31.2 1.2 2.1e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like HEAT_2 PF13646.1 KII93991.1 - 2e-07 31.1 1.2 0.071 13.3 0.0 4.0 4 1 0 4 4 4 2 HEAT repeats Arm PF00514.18 KII93991.1 - 0.00049 19.8 3.1 0.0051 16.5 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KII93991.1 - 0.0013 18.4 2.2 0.49 10.0 0.0 3.1 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 KII93991.1 - 0.0025 18.2 2.1 3.8 8.1 0.1 5.2 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KII93991.1 - 0.051 13.6 4.6 10 6.5 0.1 4.8 5 0 0 5 5 5 0 HEAT repeat VHS PF00790.14 KII93991.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 VHS domain Mg-por_mtran_C PF07109.6 KII93992.1 - 0.095 12.7 0.0 0.34 10.9 0.0 1.8 1 1 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus F-box-like PF12937.2 KII93994.1 - 0.0044 16.7 0.1 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Wbp11 PF09429.5 KII93995.1 - 1.6e-19 69.6 9.6 2.9e-19 68.8 6.7 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.2 KII93995.1 - 1.5e-16 60.5 1.4 1.5e-16 60.5 1.0 8.7 5 2 1 6 6 6 1 mRNA biogenesis factor Cas_DxTHG PF09455.5 KII93995.1 - 0.43 9.6 2.5 0.58 9.2 1.7 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family zf-C3HC4_2 PF13923.1 KII93996.1 - 4.4e-10 39.4 11.2 7e-10 38.7 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII93996.1 - 3.3e-09 36.2 7.8 5.6e-09 35.5 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII93996.1 - 7.8e-08 32.0 10.0 1.2e-07 31.3 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KII93996.1 - 2.8e-06 27.1 10.5 4.5e-06 26.4 7.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KII93996.1 - 3.5e-06 26.5 5.9 5.3e-06 26.0 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII93996.1 - 2.1e-05 24.1 7.0 4.2e-05 23.1 4.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KII93996.1 - 4.3e-05 23.1 5.5 4.9e-05 22.9 2.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KII93996.1 - 0.012 15.6 4.5 0.027 14.5 3.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 KII93996.1 - 0.016 14.6 6.0 0.031 13.8 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KII93996.1 - 0.018 14.5 10.1 0.032 13.7 7.0 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 KII93996.1 - 0.17 11.7 4.3 0.32 10.8 3.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KII93996.1 - 1.4 8.7 4.5 4.6 7.1 3.2 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein SH3_1 PF00018.23 KII93997.1 - 2.1e-11 42.9 0.1 3.7e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII93997.1 - 4e-09 35.8 0.0 7.2e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KII93997.1 - 8.1e-09 34.9 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain AzlD PF05437.7 KII93998.1 - 2.8 7.9 10.2 1.2 9.1 1.8 2.9 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) SET PF00856.23 KII94000.1 - 8.7e-09 35.8 0.0 2e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 SET domain SAF PF08666.7 KII94000.1 - 0.13 12.6 0.0 5.1 7.5 0.0 2.4 2 0 0 2 2 2 0 SAF domain MAPEG PF01124.13 KII94001.1 - 0.00066 19.2 3.7 0.00066 19.2 2.5 1.8 2 1 0 2 2 2 1 MAPEG family CcmD PF04995.9 KII94001.1 - 2.3 8.0 6.3 4.5 7.0 0.0 3.1 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) UQ_con PF00179.21 KII94003.1 - 2.1e-25 88.7 0.0 4.8e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KII94003.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain ICL PF00463.16 KII94004.1 - 2.1e-192 640.0 0.1 2.4e-192 639.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KII94004.1 - 2.2e-11 43.4 2.2 8.1e-10 38.3 0.0 2.9 2 1 1 3 3 3 2 Phosphoenolpyruvate phosphomutase FAD_binding_4 PF01565.18 KII94006.1 - 5.9e-17 61.4 0.1 1.2e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KII94006.1 - 2.4e-08 33.7 0.3 5.8e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like AP_endonuc_2 PF01261.19 KII94006.1 - 0.09 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HLH PF00010.21 KII94007.1 - 2.5e-11 43.1 0.3 2.7e-10 39.8 0.5 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Atg14 PF10186.4 KII94007.1 - 0.01 14.8 2.7 0.012 14.5 1.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 KII94007.1 - 0.015 15.2 1.7 0.03 14.3 1.2 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mt_ATP-synt_B PF05405.9 KII94007.1 - 0.029 13.8 1.8 0.036 13.5 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4200 PF13863.1 KII94007.1 - 0.26 11.2 9.4 0.38 10.7 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_int_SAM_2 PF12834.2 KII94007.1 - 0.37 11.2 2.4 1 9.7 1.6 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal DUF342 PF03961.8 KII94007.1 - 0.84 7.9 3.0 1 7.6 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 KII94007.1 - 5.4 6.5 7.6 2.5 7.6 0.6 2.3 1 1 0 2 2 2 0 Septum formation initiator 5TM-5TMR_LYT PF07694.7 KII94008.1 - 0.11 11.8 12.4 0.02 14.2 6.0 1.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT HLH PF00010.21 KII94009.1 - 3.1e-09 36.4 1.5 6.9e-09 35.2 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Orbi_VP5 PF00901.12 KII94009.1 - 0.38 8.9 6.8 0.5 8.5 4.7 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TBCA PF02970.11 KII94011.1 - 4.2e-19 68.4 1.8 5.4e-19 68.0 1.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A AIP3 PF03915.8 KII94011.1 - 0.03 13.2 0.4 0.031 13.1 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Med11 PF10280.4 KII94012.1 - 0.068 13.2 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 Mediator complex protein YfhD PF14151.1 KII94012.1 - 5.3 7.2 6.7 9.1 6.4 0.5 2.6 3 0 0 3 3 3 0 YfhD-like protein Het-C PF07217.6 KII94013.1 - 1.7e-200 667.2 0.0 1.1e-199 664.5 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Bromodomain PF00439.20 KII94014.1 - 1.5e-58 194.6 0.0 6.1e-19 67.7 0.0 3.8 4 0 0 4 4 4 3 Bromodomain Peptidase_M1 PF01433.15 KII94014.1 - 9.8e-10 38.0 0.0 8.9e-06 25.0 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 LTV PF04180.9 KII94015.1 - 1.9e-62 212.1 29.0 2.8e-45 155.6 6.2 3.1 2 1 0 3 3 3 3 Low temperature viability protein Wzz PF02706.10 KII94015.1 - 0.085 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Chain length determinant protein PIP5K PF01504.13 KII94016.1 - 6.4e-66 222.0 0.1 1.1e-65 221.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KII94016.1 - 7.5e-28 97.3 0.0 1.3e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KII94016.1 - 3.2e-17 62.1 14.9 3.3e-17 62.1 8.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 KII94016.1 - 8.5 6.3 12.6 1.3 8.9 5.6 2.0 2 0 0 2 2 2 0 IBR domain UCH PF00443.24 KII94018.1 - 2.2e-28 99.1 0.0 3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KII94018.1 - 1.9e-10 40.7 0.0 3.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein GLTSCR1 PF15249.1 KII94018.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region Rsm22 PF09243.5 KII94019.1 - 1e-43 149.3 0.0 1.6e-40 138.8 0.0 3.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.16 KII94020.1 - 2.5e-19 69.5 0.3 3.9e-19 68.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.4 KII94021.1 - 2.4e-11 43.6 2.3 1.4e-09 38.0 0.6 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 WASH-7_N PF14745.1 KII94021.1 - 0.08 11.1 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal PCI PF01399.22 KII94022.1 - 3.7e-19 68.9 0.2 1.1e-18 67.4 0.1 1.9 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KII94022.1 - 5.2e-10 39.2 0.5 1.2e-09 38.0 0.3 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 KII94022.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator dsrm PF00035.20 KII94023.1 - 5.9e-10 39.5 0.0 7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 KII94024.1 - 1.2e-07 32.1 0.0 3.5e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif WD40 PF00400.27 KII94026.1 - 1.7e-54 179.8 20.8 7.8e-09 35.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KII94026.1 - 0.00091 18.9 0.0 0.58 9.8 0.0 2.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Myosin_tail_1 PF01576.14 KII94027.1 - 0.00016 19.5 66.2 0.00016 19.5 45.9 3.1 2 1 1 3 3 3 2 Myosin tail DUF4435 PF14491.1 KII94027.1 - 0.07 12.9 0.0 0.07 12.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4435) Reo_sigmaC PF04582.7 KII94027.1 - 2.7 7.0 55.8 0.086 12.0 6.7 6.1 1 1 6 7 7 7 0 Reovirus sigma C capsid protein EFG_IV PF03764.13 KII94028.1 - 0.28 10.7 0.0 0.5 9.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV DUF3037 PF11236.3 KII94028.1 - 0.28 11.2 0.0 0.8 9.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DUF2404 PF10296.4 KII94029.1 - 9.6e-28 96.1 0.0 1.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH_9 PF15410.1 KII94029.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2414 PF10309.4 KII94031.1 - 1.9e-06 27.4 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KII94031.1 - 0.00058 19.7 0.1 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain DUF837 PF05769.6 KII94032.1 - 4.4e-09 36.1 6.2 6e-06 25.9 2.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF837) NYD-SP28_assoc PF14775.1 KII94032.1 - 0.0039 16.8 7.0 0.28 10.8 0.2 3.2 2 0 0 2 2 2 2 Sperm tail C-terminal domain SlyX PF04102.7 KII94032.1 - 0.054 13.8 11.0 0.22 11.9 0.4 4.2 4 0 0 4 4 4 0 SlyX Gsf2 PF11055.3 KII94032.1 - 0.074 11.5 0.2 0.099 11.1 0.1 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 DivIC PF04977.10 KII94032.1 - 0.36 10.3 5.9 9.1 5.8 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator Herpes_BLRF2 PF05812.7 KII94032.1 - 1.2 8.9 6.2 5.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein DUF904 PF06005.7 KII94032.1 - 2.2 8.6 8.2 7.8 6.8 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DSHCT PF08148.7 KII94033.1 - 7e-60 201.3 0.1 1.6e-59 200.2 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KII94033.1 - 2.8e-21 75.7 0.0 5.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 KII94033.1 - 1.8e-12 47.0 0.0 2.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 KII94033.1 - 8.3e-06 25.5 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII94033.1 - 0.063 13.0 0.1 0.62 9.8 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 KII94035.1 - 1.4e-29 102.6 0.0 1.9e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII94035.1 - 2.1e-26 92.2 0.0 3.4e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KII94035.1 - 6e-18 64.8 0.0 9.6e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KII94035.1 - 7.6e-18 64.7 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII94035.1 - 7.7e-18 64.7 0.1 1.9e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII94035.1 - 1.3e-16 61.1 0.0 2.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII94035.1 - 3.2e-16 59.6 0.0 5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII94035.1 - 8.9e-11 41.8 0.2 2e-10 40.6 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KII94035.1 - 4.1e-10 39.5 0.0 6.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KII94035.1 - 1e-08 34.7 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 KII94035.1 - 3.5e-07 29.4 0.0 5.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KII94035.1 - 1.7e-06 27.5 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KII94035.1 - 0.00016 20.4 0.0 0.00038 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.11 KII94035.1 - 0.00017 20.0 0.1 0.00048 18.5 0.0 1.5 1 1 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 KII94035.1 - 0.00025 20.2 0.0 0.0003 19.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KII94035.1 - 0.0006 19.2 0.0 0.00082 18.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KII94035.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 KII94035.1 - 0.0015 17.4 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase UPF0020 PF01170.13 KII94035.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 KII94035.1 - 0.024 13.7 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KII94035.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ist1 PF03398.9 KII94036.1 - 7.5e-63 210.8 2.7 9.3e-63 210.5 1.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Methyltransf_23 PF13489.1 KII94038.1 - 2.6e-09 37.0 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII94038.1 - 6.4e-08 32.9 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII94038.1 - 5e-05 22.4 0.0 0.00026 20.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII94038.1 - 7.4e-05 23.2 0.1 0.00053 20.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KII94038.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KII94038.1 - 0.00049 19.7 0.0 0.0052 16.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII94038.1 - 0.0006 20.2 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KII94038.1 - 0.0074 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KII94038.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KII94038.1 - 0.014 15.7 0.0 0.058 13.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain RasGEF PF00617.14 KII94039.1 - 1.4e-42 145.5 0.1 2.3e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII94039.1 - 8.5e-20 70.8 0.1 1.8e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KII94039.1 - 7.1e-12 44.5 0.0 1.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII94039.1 - 2.1e-08 33.5 0.0 4.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KII94039.1 - 5.9e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4231 PF14015.1 KII94039.1 - 0.091 12.7 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ras PF00071.17 KII94040.1 - 3.3e-59 198.8 0.1 3.9e-59 198.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII94040.1 - 4.1e-20 72.4 0.0 5.6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII94040.1 - 9.5e-14 51.0 0.1 1.1e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII94040.1 - 3.1e-06 26.7 0.0 6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII94040.1 - 7.3e-06 25.9 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KII94040.1 - 9e-06 24.9 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KII94040.1 - 0.043 13.7 0.2 0.15 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KII94040.1 - 0.045 12.9 0.1 0.14 11.3 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KII94040.1 - 0.05 12.7 0.1 0.14 11.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 KII94040.1 - 0.058 12.4 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 KII94040.1 - 0.11 11.1 0.3 5.5 5.5 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 KII94040.1 - 0.12 12.4 0.0 0.51 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 KII94041.1 - 7.7e-15 54.2 0.1 3.5e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94041.1 - 1.3e-08 34.6 0.1 3.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94041.1 - 1.3e-07 31.3 0.0 0.0004 20.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KII94041.1 - 0.22 11.3 0.1 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 KII94042.1 - 4.6e-27 92.8 18.1 1.1e-07 31.5 1.4 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KII94042.1 - 0.09 10.8 0.4 7.3 4.5 0.0 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF1391 PF07151.7 KII94042.1 - 0.12 11.8 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) PQQ_3 PF13570.1 KII94042.1 - 0.3 11.4 3.2 19 5.7 0.2 3.5 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 KII94043.1 - 4.3e-57 188.0 4.2 3.3e-11 42.6 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KII94043.1 - 2.4e-08 33.9 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KII94043.1 - 9e-07 28.4 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.11 KII94043.1 - 0.00076 17.8 0.0 0.44 8.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 KII94043.1 - 0.011 14.7 0.0 0.3 10.1 0.0 2.8 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KII94043.1 - 0.026 12.6 0.5 0.35 8.9 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KII94043.1 - 0.085 12.3 0.0 3 7.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Bax1-I PF01027.15 KII94044.1 - 1.3e-35 122.8 8.1 5.1e-35 120.9 5.6 1.7 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Sec1 PF00995.18 KII94045.1 - 4.3e-144 481.2 0.0 4.9e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RVT_1 PF00078.22 KII94046.1 - 1.2e-05 24.8 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KII94047.1 - 3e-07 30.0 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF221 PF02714.10 KII94048.1 - 4.9e-13 48.6 12.2 9.8e-13 47.6 8.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KII94048.1 - 6.6e-05 22.5 0.4 6.6e-05 22.5 0.3 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KII94048.1 - 0.00018 21.3 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KII94048.1 - 0.0077 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) bZIP_1 PF00170.16 KII94048.1 - 0.056 13.3 1.0 0.11 12.4 0.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor RicinB_lectin_2 PF14200.1 KII94049.1 - 0.018 15.4 0.0 0.056 13.8 0.0 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Arginase PF00491.16 KII94050.1 - 4.9e-82 275.3 0.0 6.2e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KII94050.1 - 0.091 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain SUR7 PF06687.7 KII94051.1 - 1.7e-20 73.4 17.7 2.4e-20 73.0 12.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KII94051.1 - 0.16 11.6 17.3 0.27 10.9 12.0 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KII94051.1 - 6.7 5.9 10.3 0.18 11.0 2.5 1.7 2 0 0 2 2 2 0 Clc-like Acetyltransf_3 PF13302.1 KII94052.1 - 9.4e-21 74.4 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII94052.1 - 0.0004 20.3 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KII94052.1 - 0.0043 16.9 0.0 0.062 13.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII94052.1 - 0.042 13.5 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 KII94052.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII94052.1 - 0.081 12.8 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.22 KII94053.1 - 1.1e-62 210.7 0.1 1.6e-62 210.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KII94053.1 - 3e-38 130.0 0.0 6.4e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KII94053.1 - 1.2e-20 73.1 0.0 3.1e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KII94053.1 - 3.5e-13 49.1 0.0 8.6e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KII94053.1 - 1.9e-09 37.4 0.0 8.3e-09 35.4 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII94053.1 - 1.7e-05 24.7 0.2 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KII94053.1 - 0.069 12.6 0.8 0.25 10.8 0.3 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.23 KII94054.1 - 1e-07 31.5 2.4 4.2e-07 29.5 1.6 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII94054.1 - 0.022 14.5 0.0 0.1 12.4 0.0 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPR_10 PF13374.1 KII94055.1 - 0.044 13.7 1.0 5.6 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KII94055.1 - 0.044 13.9 0.3 1.1 9.4 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ArsA_ATPase PF02374.10 KII94056.1 - 2.8e-110 368.1 1.0 3.2e-110 367.9 0.7 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KII94056.1 - 1e-15 57.7 0.0 1.6e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KII94056.1 - 2.4e-09 37.3 0.0 5.7e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KII94056.1 - 1.1e-05 24.7 0.1 3.8e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KII94056.1 - 0.00013 21.4 0.5 0.0027 17.1 0.1 2.6 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 KII94056.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 KII94056.1 - 0.0015 17.9 0.1 0.0075 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KII94056.1 - 0.0073 16.0 0.0 0.057 13.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain MipZ PF09140.6 KII94056.1 - 0.0082 15.2 0.1 0.019 14.0 0.1 1.7 1 1 0 1 1 1 1 ATPase MipZ IstB_IS21 PF01695.12 KII94056.1 - 0.058 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 KII94056.1 - 0.075 12.2 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein VirC1 PF07015.6 KII94056.1 - 0.08 11.9 1.0 0.17 10.9 0.1 1.9 2 1 0 2 2 2 0 VirC1 protein AAA_24 PF13479.1 KII94056.1 - 0.091 12.3 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 KII94057.1 - 3.7e-11 42.8 13.8 7.8e-11 41.7 9.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 KII94057.1 - 9.5e-10 38.6 0.0 9.5e-10 38.6 0.0 4.0 2 1 1 3 3 3 1 Transcription factor PAP1 bZIP_2 PF07716.10 KII94057.1 - 0.00051 19.8 14.8 0.00051 19.8 10.3 2.9 2 1 1 3 3 3 1 Basic region leucine zipper DUF972 PF06156.8 KII94057.1 - 0.024 14.9 0.5 0.07 13.4 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Jnk-SapK_ap_N PF09744.4 KII94057.1 - 0.31 11.0 5.7 0.53 10.2 3.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 KII94057.1 - 4.4 6.8 12.6 0.023 14.1 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator zf-CGNR PF11706.3 KII94058.1 - 0.41 10.1 2.1 9.3 5.8 0.2 2.2 2 0 0 2 2 2 0 CGNR zinc finger Isochorismatase PF00857.15 KII94059.1 - 3.9e-07 30.1 0.0 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Isochorismatase family Telomere_Sde2 PF13019.1 KII94059.1 - 0.065 12.9 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Telomere stability and silencing Isochorismatase PF00857.15 KII94060.1 - 1.2e-06 28.5 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family EVC2_like PF12297.3 KII94061.1 - 0.1 11.2 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein OppC_N PF12911.2 KII94061.1 - 0.15 11.4 2.9 0.34 10.3 2.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Ras PF00071.17 KII94063.1 - 5.7e-54 181.8 0.0 6.8e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII94063.1 - 1e-17 64.7 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII94063.1 - 1.2e-12 47.4 0.0 1.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII94063.1 - 4e-06 26.4 0.0 4.7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII94063.1 - 9.4e-05 22.3 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KII94063.1 - 0.00015 20.9 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KII94063.1 - 0.0045 17.1 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII94063.1 - 0.0067 16.4 0.6 0.014 15.3 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 KII94063.1 - 0.0073 15.8 0.0 0.45 10.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 KII94063.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KaiC PF06745.8 KII94063.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 KII94063.1 - 0.029 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Methyltransf_25 PF13649.1 KII94063.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ABC_tran PF00005.22 KII94063.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.4 KII94063.1 - 0.059 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 KII94063.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UbiD PF01977.11 KII94063.1 - 0.071 11.5 0.0 0.09 11.2 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Septin PF00735.13 KII94063.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Septin D-ser_dehydrat PF14031.1 KII94064.1 - 1.4e-18 66.8 0.1 1.6e-17 63.4 0.0 2.6 2 1 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KII94064.1 - 2.8e-09 36.8 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4126 PF13548.1 KII94064.1 - 2.9 7.2 5.9 0.55 9.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4126) Abhydrolase_3 PF07859.8 KII94065.1 - 2.8e-64 216.5 0.0 3.9e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KII94065.1 - 5e-11 42.0 2.0 1.1e-10 40.9 1.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 KII94065.1 - 1.1e-05 24.4 0.0 1.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 KII94065.1 - 1.2e-05 24.1 0.0 1.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 KII94065.1 - 2.9e-05 23.0 0.0 6.6e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S9 PF00326.16 KII94065.1 - 5.8e-05 22.4 0.0 0.00021 20.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII94065.1 - 0.00022 20.9 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KII94065.1 - 0.047 13.0 0.3 0.18 11.1 0.2 1.9 1 1 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.8 KII94065.1 - 0.18 10.0 0.1 1.4 7.1 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II COX5A PF02284.11 KII94066.1 - 2e-40 137.1 0.3 2.8e-40 136.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Acetyltransf_1 PF00583.19 KII94067.1 - 1.3e-10 41.1 0.1 2.2e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KII94067.1 - 2e-09 37.0 0.0 3.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KII94067.1 - 3e-06 27.3 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KII94067.1 - 4.3e-06 26.7 0.0 1e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII94067.1 - 5.5e-06 26.3 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII94067.1 - 2.3e-05 24.2 0.0 5.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII94067.1 - 0.0052 16.9 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain BSP PF04450.7 KII94067.1 - 0.028 13.8 0.1 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria RNase_P_pop3 PF08228.6 KII94068.1 - 9.1e-15 54.8 0.1 1.5e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit Pop3 Suf PF05843.9 KII94068.1 - 0.014 15.0 0.1 0.014 15.0 0.1 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Rotamase_2 PF13145.1 KII94068.1 - 0.061 13.9 8.6 0.17 12.5 1.6 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF3857 PF12969.2 KII94068.1 - 0.14 11.7 1.6 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) F-box PF00646.28 KII94069.1 - 0.00024 20.6 0.3 0.0014 18.2 0.2 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII94069.1 - 0.00072 19.2 0.1 0.0027 17.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like dCMP_cyt_deam_1 PF00383.17 KII94070.1 - 6.7e-24 83.4 0.6 1.1e-23 82.7 0.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region HEAT PF02985.17 KII94071.1 - 2.9e-06 26.9 0.7 0.063 13.3 0.0 4.4 3 0 0 3 3 3 2 HEAT repeat Chorismate_bind PF00425.13 KII94072.1 - 1.6e-66 224.2 0.0 2.1e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KII94072.1 - 7.4e-35 120.1 0.0 1.3e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KII94072.1 - 3.6e-16 59.4 0.0 8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KII94072.1 - 4.7e-05 22.9 0.1 9.1e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 F-box-like PF12937.2 KII94073.1 - 9.1e-05 22.1 0.5 0.00019 21.0 0.1 1.8 2 0 0 2 2 2 1 F-box-like Homeobox PF00046.24 KII94074.1 - 1e-15 57.0 1.2 1.8e-15 56.2 0.8 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KII94074.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain CENP-T PF15511.1 KII94075.1 - 0.023 13.9 6.8 0.027 13.7 4.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Methyltransf_24 PF13578.1 KII94076.1 - 4.7e-11 43.4 0.0 8.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KII94076.1 - 0.0013 18.6 1.3 0.0018 18.2 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_3 PF01596.12 KII94076.1 - 0.031 13.3 0.0 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase Abhydrolase_5 PF12695.2 KII94076.1 - 0.039 13.7 0.0 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family PB1 PF00564.19 KII94077.1 - 7.2e-08 31.9 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 PB1 domain MAP65_ASE1 PF03999.7 KII94077.1 - 0.0096 14.5 1.3 0.017 13.7 0.9 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) PV-1 PF06637.6 KII94077.1 - 0.41 9.1 1.3 0.78 8.2 0.9 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3987 PF13148.1 KII94077.1 - 0.82 8.1 5.0 1.9 6.9 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4337 PF14235.1 KII94077.1 - 6.1 6.6 4.7 13 5.5 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Aldo_ket_red PF00248.16 KII94078.1 - 5.1e-45 153.4 0.0 5.9e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ApbA_C PF08546.6 KII94079.1 - 1.1e-35 122.3 0.1 2e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KII94079.1 - 1.9e-19 69.6 0.5 3.4e-18 65.5 0.3 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KII94079.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF2371 PF10177.4 KII94080.1 - 0.024 14.4 0.0 0.14 11.9 0.0 2.2 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF872 PF05915.7 KII94080.1 - 0.09 12.6 0.3 0.31 10.9 0.2 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) O-FucT PF10250.4 KII94081.1 - 2.3e-10 40.1 0.0 4.6e-09 35.8 0.0 2.5 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase TPT PF03151.11 KII94082.1 - 3.8e-06 26.6 10.7 3.8e-06 26.6 7.4 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KII94082.1 - 0.73 9.8 34.9 2 8.4 8.4 3.2 2 2 1 3 3 3 0 EamA-like transporter family Arteri_Gl PF00951.13 KII94083.1 - 0.085 12.4 0.0 0.099 12.2 0.0 1.0 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein AATase PF07247.7 KII94084.1 - 0.0008 18.0 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KII94084.1 - 0.013 14.3 0.3 1.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Condensation domain YccV-like PF08755.6 KII94085.1 - 1.2e-20 73.2 0.0 2.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KII94085.1 - 3.2e-11 42.9 0.0 6.8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1741 PF08427.5 KII94087.1 - 4.1e-36 124.6 0.2 1.1e-35 123.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) GDC-P PF02347.11 KII94088.1 - 1.4e-185 617.0 0.0 7.1e-174 578.4 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KII94088.1 - 4.7e-06 25.9 0.1 8.9e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KII94088.1 - 1.3e-05 24.1 0.2 0.00011 21.0 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V PPR_2 PF13041.1 KII94089.1 - 4.1e-28 97.1 0.0 0.0026 17.6 0.0 9.5 9 2 1 10 10 10 7 PPR repeat family PPR PF01535.15 KII94089.1 - 1.1e-16 59.5 4.8 0.0059 16.4 0.0 9.7 10 0 0 10 10 10 3 PPR repeat PPR_3 PF13812.1 KII94089.1 - 4.8e-16 57.6 1.8 0.26 11.6 0.0 11.3 14 0 0 14 14 14 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 KII94089.1 - 1.2e-08 34.3 0.2 0.43 10.1 0.0 8.1 9 0 0 9 9 9 1 PPR repeat SecE PF00584.15 KII94090.1 - 3.3e-13 48.9 0.0 3.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.5 KII94090.1 - 0.13 12.1 0.1 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Vps51 PF08700.6 KII94092.1 - 2.3e-15 56.1 0.7 9.5e-15 54.2 0.5 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 KII94092.1 - 0.017 14.8 0.6 0.054 13.2 0.4 1.9 1 0 0 1 1 1 0 Exocyst complex component Sec5 COG2 PF06148.6 KII94092.1 - 0.59 10.0 3.8 0.36 10.7 0.7 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1751 PF08551.5 KII94093.1 - 1.2e-27 96.1 2.6 2.2e-27 95.2 1.8 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Ribosomal_60s PF00428.14 KII94093.1 - 0.47 10.8 4.2 0.77 10.2 2.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2975 PF11188.3 KII94093.1 - 0.69 9.6 9.4 0.8 9.4 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF1754 PF08555.5 KII94094.1 - 1.9e-14 54.0 8.2 1.9e-14 54.0 5.7 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF1777 PF08648.7 KII94094.1 - 0.0042 16.8 14.5 0.0055 16.4 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF4191 PF13829.1 KII94094.1 - 0.0058 15.7 0.8 0.0093 15.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4191) ELL PF10390.4 KII94094.1 - 0.075 12.2 2.4 0.089 12.0 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL PP2C_C PF07830.8 KII94094.1 - 0.11 12.5 0.3 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain SAGA-Tad1 PF12767.2 KII94094.1 - 0.17 11.5 3.6 0.2 11.3 2.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Host_attach PF10116.4 KII94094.1 - 0.44 10.7 6.4 0.83 9.8 3.1 1.9 1 1 1 2 2 2 0 Protein required for attachment to host cells U79_P34 PF03064.11 KII94094.1 - 0.76 9.2 12.7 0.94 8.9 8.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FbpA PF05833.6 KII94094.1 - 2.8 6.3 7.8 0.044 12.3 0.5 1.5 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) SUKH-3 PF14433.1 KII94095.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 SUKH-3 immunity protein Cullin_Nedd8 PF10557.4 KII94095.1 - 0.16 11.8 1.7 0.25 11.2 0.4 1.9 2 0 0 2 2 2 0 Cullin protein neddylation domain CDC45 PF02724.9 KII94095.1 - 4.6 5.1 6.8 5.9 4.8 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M3 PF01432.15 KII94096.1 - 1.6e-130 436.2 0.0 2e-130 435.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Mating_C PF12737.2 KII94098.1 - 6.6e-20 71.3 82.9 3.1e-12 46.1 32.5 4.1 2 1 1 3 3 3 2 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 KII94098.1 - 6.3e-14 51.3 0.6 1.8e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Mating_N PF12731.2 KII94098.1 - 2.1e-06 27.5 2.2 2.1e-06 27.5 1.5 1.8 2 0 0 2 2 2 1 Mating-type protein beta 1 MerR-DNA-bind PF09278.6 KII94098.1 - 0.083 13.3 0.1 0.083 13.3 0.1 2.9 3 0 0 3 3 3 0 MerR, DNA binding Homeobox PF00046.24 KII94099.1 - 7.3e-13 47.9 0.6 1.6e-12 46.8 0.4 1.6 1 0 0 1 1 1 1 Homeobox domain AalphaY_MDB PF04611.7 KII94099.1 - 8e-06 25.8 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Mating type protein A alpha Y mating type dependent binding region Homeobox_KN PF05920.6 KII94099.1 - 2.7e-05 23.7 0.6 8.9e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 KII94099.1 - 0.00015 20.7 0.1 0.00033 19.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Mating_C PF12737.2 KII94101.1 - 9.6e-18 64.2 67.7 2.1e-10 40.0 11.7 4.4 2 1 1 3 3 3 2 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 KII94101.1 - 7.1e-14 51.2 0.1 2.7e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Mating_N PF12731.2 KII94101.1 - 4.6e-08 32.8 1.4 1.2e-07 31.5 0.9 1.7 1 0 0 1 1 1 1 Mating-type protein beta 1 MerR-DNA-bind PF09278.6 KII94101.1 - 0.0063 16.8 0.4 0.0063 16.8 0.2 2.5 3 0 0 3 3 3 1 MerR, DNA binding DUF4317 PF14199.1 KII94101.1 - 0.088 11.5 0.2 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) DUF3759 PF12585.3 KII94103.1 - 0.0079 16.0 0.3 0.015 15.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Apolipoprotein PF01442.13 KII94104.1 - 5.6e-05 22.7 2.3 0.00022 20.7 1.6 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 KII94104.1 - 0.0021 17.8 0.7 0.0021 17.8 0.5 2.6 2 1 0 2 2 2 1 ATP synthase B/B' CF(0) DUF883 PF05957.8 KII94104.1 - 0.0044 17.3 10.6 0.062 13.7 0.4 3.1 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.4 KII94104.1 - 0.022 13.4 4.5 0.026 13.2 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FIVAR PF07554.8 KII94104.1 - 0.079 13.2 7.3 1.8 8.8 0.0 3.9 2 1 1 3 3 3 0 Uncharacterised Sugar-binding Domain EF-hand_7 PF13499.1 KII94105.1 - 1.9e-10 40.7 3.0 7.6e-09 35.5 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KII94105.1 - 4.6e-10 38.5 1.5 2.5e-05 23.7 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KII94105.1 - 4.5e-08 31.8 7.8 2.1e-05 23.4 0.2 3.6 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 KII94105.1 - 0.023 14.0 1.8 0.077 12.3 0.4 2.2 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.1 KII94105.1 - 0.036 13.9 0.0 14 5.6 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 KII94105.1 - 3.3 7.4 7.4 14 5.4 0.0 3.4 2 2 1 3 3 3 0 EF-hand domain pair F-box-like PF12937.2 KII94106.1 - 3.7e-11 42.5 0.7 1e-10 41.1 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII94106.1 - 1.3e-06 27.9 0.4 3.1e-06 26.6 0.3 1.8 1 0 0 1 1 1 1 F-box domain adh_short PF00106.20 KII94107.1 - 4.1e-25 88.6 0.1 6.7e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII94107.1 - 4.6e-18 65.8 0.1 5.9e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KII94107.1 - 1.6e-08 34.0 0.0 3.7e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KII94107.1 - 1.1e-05 25.0 0.2 2e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KII94107.1 - 1.4e-05 24.8 0.1 3.1e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII94107.1 - 0.00057 19.9 0.1 0.001 19.1 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KII94107.1 - 0.0072 15.2 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 KII94107.1 - 0.011 15.3 0.1 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CENP-S PF15630.1 KII94107.1 - 0.044 13.9 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore component CENP-S NAD_binding_2 PF03446.10 KII94107.1 - 0.098 12.4 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PAE PF03283.8 KII94107.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase PAP2 PF01569.16 KII94108.1 - 8.1e-15 54.6 8.0 1.3e-14 53.9 5.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KII94108.1 - 0.00032 20.4 0.4 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 1 Divergent PAP2 family PI-PLC-X PF00388.14 KII94109.1 - 0.00012 21.4 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Sigma54_AID PF00309.15 KII94109.1 - 0.025 14.0 1.1 0.053 13.0 0.8 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Utp11 PF03998.8 KII94110.1 - 2.5e-59 201.0 22.2 7e-59 199.5 15.4 1.7 1 1 0 1 1 1 1 Utp11 protein Vpu PF00558.14 KII94110.1 - 0.055 13.0 0.1 0.055 13.0 0.1 2.8 3 0 0 3 3 3 0 Vpu protein DNase_NucA_NucB PF14040.1 KII94110.1 - 0.29 11.3 0.1 0.29 11.3 0.1 2.4 3 0 0 3 3 3 0 Deoxyribonuclease NucA/NucB FAR1 PF03101.10 KII94111.1 - 0.033 14.7 0.2 0.051 14.0 0.2 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain VHS PF00790.14 KII94112.1 - 2.4e-28 98.5 0.0 4.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KII94112.1 - 8.4e-07 28.8 0.4 6.1e-06 26.1 0.3 2.3 2 0 0 2 2 2 1 GAT domain RR_TM4-6 PF06459.7 KII94112.1 - 0.07 13.0 7.5 0.2 11.5 2.3 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 KII94112.1 - 2.8 6.6 19.5 2.1 7.0 0.0 2.5 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 zf-RING_2 PF13639.1 KII94113.1 - 5.7e-14 51.6 4.1 1.1e-13 50.7 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KII94113.1 - 1.2e-10 40.9 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.1 KII94113.1 - 7.1e-07 28.8 2.2 1.2e-06 28.1 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KII94113.1 - 2.5e-06 27.5 2.4 5.9e-06 26.2 1.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KII94113.1 - 7.8e-06 25.4 1.9 1.4e-05 24.6 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII94113.1 - 1.2e-05 25.2 4.0 2.2e-05 24.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII94113.1 - 6.4e-05 22.5 2.6 0.00011 21.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII94113.1 - 0.036 13.9 1.4 0.099 12.4 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KII94113.1 - 0.79 9.7 5.6 2.6 8.0 2.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain tRNA-synt_2b PF00587.20 KII94114.1 - 2.8e-27 95.4 0.0 4.2e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KII94114.1 - 5.8e-08 32.7 0.6 9e-08 32.1 0.4 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Rep_fac_C PF08542.6 KII94115.1 - 1.6e-21 76.1 0.0 4e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KII94115.1 - 6.5e-12 45.7 0.1 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KII94115.1 - 6.6e-12 45.3 0.1 5.2e-10 39.2 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KII94115.1 - 3.7e-07 30.0 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII94115.1 - 4.2e-06 26.8 0.1 5.5e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KII94115.1 - 6.2e-06 26.3 0.1 0.00087 19.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KII94115.1 - 1.6e-05 23.8 0.2 0.046 12.4 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 KII94115.1 - 2.5e-05 23.9 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KII94115.1 - 3.5e-05 23.4 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KII94115.1 - 0.0001 21.4 0.0 0.00024 20.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 KII94115.1 - 0.00088 18.7 0.2 0.17 11.2 0.0 2.4 2 1 1 3 3 3 1 AAA-like domain DNA_pol3_delta PF06144.8 KII94115.1 - 0.002 17.6 0.1 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 KII94115.1 - 0.0043 16.2 0.0 0.046 12.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KII94115.1 - 0.0043 15.8 0.0 0.014 14.1 0.0 1.7 1 1 1 2 2 2 1 ArgK protein AAA_19 PF13245.1 KII94115.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 KII94115.1 - 0.0059 16.3 0.2 0.049 13.3 0.1 2.1 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.1 KII94115.1 - 0.035 14.3 0.1 0.059 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KII94115.1 - 0.041 14.0 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.24 KII94115.1 - 0.054 12.9 0.1 0.52 9.7 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.17 KII94115.1 - 0.058 12.8 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.1 KII94115.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KII94115.1 - 0.083 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KII94115.1 - 0.085 13.1 0.1 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ParA PF10609.4 KII94116.1 - 3.6e-32 110.0 0.2 6.1e-32 109.3 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KII94116.1 - 3.3e-12 46.2 0.0 6.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KII94116.1 - 2.9e-06 26.5 0.3 0.00041 19.5 0.1 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.1 KII94116.1 - 1.6e-05 24.9 0.0 0.0005 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KII94116.1 - 8.8e-05 21.7 0.0 0.0044 16.1 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ DUF258 PF03193.11 KII94116.1 - 0.0079 15.3 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KII94116.1 - 0.015 14.6 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KII94116.1 - 0.035 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF3759 PF12585.3 KII94117.1 - 6.3e-35 118.9 5.6 8.2e-35 118.5 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) zf-C4_ClpX PF06689.8 KII94117.1 - 0.031 13.7 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Abhydrolase_6 PF12697.2 KII94120.1 - 0.0034 17.2 0.7 0.0091 15.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family adh_short PF00106.20 KII94121.1 - 1.1e-27 97.0 0.1 1.6e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII94121.1 - 1.4e-19 70.7 0.1 1.8e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII94121.1 - 3.9e-10 39.6 0.1 9.2e-10 38.4 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 KII94121.1 - 3.4e-07 29.6 0.0 5.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KII94121.1 - 1.2e-05 24.8 0.5 5.2e-05 22.8 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KII94121.1 - 3.9e-05 23.7 0.1 6.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 KII94121.1 - 0.0081 15.8 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 KII94121.1 - 0.0083 15.0 0.2 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain PAE PF03283.8 KII94121.1 - 0.017 13.7 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DUF916 PF06030.7 KII94121.1 - 0.1 12.3 0.2 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) CENP-S PF15630.1 KII94121.1 - 0.11 12.7 0.1 8.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Kinetochore component CENP-S RRM_1 PF00076.17 KII94122.1 - 8.5e-14 50.9 0.0 5.8e-08 32.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94122.1 - 5.2e-11 42.3 0.0 1.1e-06 28.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94122.1 - 1.2e-10 41.1 0.0 4.6e-06 26.3 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.17 KII94123.1 - 3.6e-22 77.8 0.2 4.4e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 HORMA PF02301.13 KII94124.1 - 2.1e-22 79.6 0.0 2.4e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PX PF00787.19 KII94125.1 - 2.7e-19 69.0 0.7 1.5e-18 66.5 0.6 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KII94125.1 - 9.6e-06 25.0 3.4 0.00023 20.4 1.6 2.8 1 1 2 3 3 3 1 Vps5 C terminal like BAR PF03114.13 KII94125.1 - 0.0031 17.0 1.7 7.5 5.9 0.3 3.4 4 0 0 4 4 4 2 BAR domain Lung_7-TM_R PF06814.8 KII94126.1 - 1.4e-62 211.3 14.5 1.8e-62 210.9 10.0 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF834 PF05754.9 KII94127.1 - 0.18 11.6 8.3 0.86 9.4 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF834) RNA_pol_Rpb2_6 PF00562.23 KII94128.1 - 6.2e-127 423.5 0.2 9.7e-127 422.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KII94128.1 - 7.8e-69 230.6 0.0 1.2e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KII94128.1 - 3.2e-48 163.6 0.1 6e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KII94128.1 - 1.3e-28 99.0 0.0 3.2e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KII94128.1 - 6e-28 96.4 0.4 1.7e-27 95.0 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KII94128.1 - 8.2e-24 83.1 0.1 1.7e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KII94128.1 - 7e-21 73.9 0.2 1.5e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MHC_II_alpha PF00993.15 KII94128.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain DUF572 PF04502.8 KII94129.1 - 0.81 8.8 0.0 0.81 8.8 0.0 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF572) Myb_DNA-binding PF00249.26 KII94131.1 - 1.6e-08 34.4 0.0 6.5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII94131.1 - 0.00084 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SIR2 PF02146.12 KII94132.1 - 4e-27 95.0 0.2 2.8e-23 82.5 0.0 3.1 2 1 0 2 2 2 2 Sir2 family Ribonuclease_T2 PF00445.13 KII94133.1 - 2.3e-33 115.4 0.2 3.7e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family MBOAT_2 PF13813.1 KII94134.1 - 1.3e-12 47.6 1.1 1.3e-12 47.6 0.8 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2306 PF10067.4 KII94134.1 - 0.032 14.3 0.7 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) SURF1 PF02104.10 KII94136.1 - 8.4e-59 198.9 0.0 1.1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 SURF1 family PsbI PF02532.9 KII94136.1 - 0.56 9.8 2.5 1.3 8.7 1.7 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) ANTH PF07651.11 KII94137.1 - 1.5e-73 246.9 0.0 1.5e-73 246.9 0.0 3.2 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.12 KII94137.1 - 1.5e-63 213.3 8.4 1.5e-63 213.3 5.8 4.9 5 0 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 KII94137.1 - 2.1e-06 27.5 0.0 1.9e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 ENTH domain DUF2284 PF10050.4 KII94137.1 - 0.21 11.1 1.5 0.81 9.2 1.0 2.0 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Ion_trans PF00520.26 KII94139.1 - 2e-05 23.9 1.4 3.4e-05 23.1 1.0 1.3 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.3 KII94140.1 - 9.9e-26 90.0 0.5 9.9e-26 90.0 0.4 3.7 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KII94140.1 - 4.6e-13 48.9 13.0 4.6e-13 48.9 9.0 3.9 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.11 KII94142.1 - 1.2e-46 159.0 34.9 1.8e-44 151.9 14.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII94142.1 - 1.4e-12 46.9 10.0 1.4e-12 46.9 6.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KII94142.1 - 2e-09 36.1 0.9 3.8e-09 35.3 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KII94142.1 - 1e-07 30.7 3.5 1e-07 30.7 2.4 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 KII94142.1 - 0.00041 18.9 1.2 0.00041 18.9 0.8 3.3 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KII94142.1 - 0.00074 19.2 0.6 0.0051 16.5 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 KII94142.1 - 0.0011 17.1 3.4 0.0021 16.2 2.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DivIC PF04977.10 KII94143.1 - 0.05 13.0 0.6 0.05 13.0 0.4 2.6 3 0 0 3 3 3 0 Septum formation initiator LPP PF04728.8 KII94143.1 - 0.4 10.5 4.9 0.26 11.0 0.9 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper zf-MYND PF01753.13 KII94145.1 - 1.6e-11 43.9 9.8 4.1e-11 42.5 6.8 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KII94145.1 - 0.058 13.2 3.9 0.12 12.2 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_transf_8 PF01501.15 KII94146.1 - 1.3e-31 109.8 0.0 1.9e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KII94146.1 - 0.041 13.2 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative ABC1 PF03109.11 KII94148.1 - 3.4e-23 81.8 0.0 6.4e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KII94148.1 - 0.019 14.6 0.1 0.36 10.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KII94149.1 - 2.2e-60 204.0 0.0 2.6e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KII94149.1 - 8.4e-11 42.0 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.2 KII94150.1 - 9.1e-07 28.5 3.5 9.4e-07 28.4 1.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII94150.1 - 0.041 13.5 0.8 0.041 13.5 0.5 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KII94151.1 - 1.3e-09 37.6 1.0 3.9e-09 36.0 0.7 1.9 1 0 0 1 1 1 1 F-box-like GARS_A PF01071.14 KII94152.1 - 1.4e-76 256.4 0.0 2e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KII94152.1 - 1.8e-33 114.9 0.0 1.7e-32 111.8 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KII94152.1 - 1.7e-31 109.2 0.0 8.1e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KII94152.1 - 5.2e-29 100.2 0.4 1.1e-28 99.2 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KII94152.1 - 2.3e-17 63.0 1.9 1.3e-16 60.5 0.7 2.8 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 KII94152.1 - 7e-08 31.5 0.0 1.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KII94152.1 - 8.4e-07 28.8 0.0 3e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KII94152.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Ank_2 PF12796.2 KII94153.1 - 3.4e-10 40.1 0.0 6.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII94153.1 - 1.4e-09 38.1 0.0 7.5e-06 26.3 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KII94153.1 - 5.9e-09 35.2 0.0 2e-07 30.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KII94153.1 - 2.3e-06 27.3 0.0 4.2e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_2 PF14608.1 KII94153.1 - 3.6e-06 26.7 15.8 9.6e-05 22.2 3.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Ank_5 PF13857.1 KII94153.1 - 2.2e-05 24.5 0.0 7.9e-05 22.7 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-CCCH PF00642.19 KII94153.1 - 5.9e-05 22.6 12.8 0.029 14.0 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_Gly3P_dh_C PF07479.9 KII94154.1 - 1.1e-47 161.4 0.1 1.7e-47 160.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KII94154.1 - 4.9e-33 114.0 0.0 8.3e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KII94154.1 - 1.6e-10 40.6 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KII94154.1 - 1.2e-05 25.6 0.0 8.2e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KII94154.1 - 0.0023 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KII94154.1 - 0.012 15.6 0.0 0.067 13.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 KII94154.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Syntaxin PF00804.20 KII94155.1 - 1.9e-17 63.3 7.9 3.2e-17 62.5 3.1 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 KII94155.1 - 2e-14 53.0 0.4 2e-14 53.0 0.3 2.7 2 1 1 3 3 3 1 SNARE domain Syntaxin-18_N PF10496.4 KII94155.1 - 0.0046 16.7 0.5 0.1 12.4 0.0 2.9 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Sed5p PF11416.3 KII94155.1 - 0.01 15.2 0.1 0.034 13.5 0.1 2.0 1 0 0 1 1 1 1 Integral membrane protein Sed5p PhaC_N PF07167.8 KII94155.1 - 0.041 13.3 1.5 0.075 12.4 0.2 2.0 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus zf-C4H2 PF10146.4 KII94155.1 - 0.13 12.2 1.9 6.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein FlaC_arch PF05377.6 KII94155.1 - 1.1 9.1 3.6 2.6 7.9 0.0 3.2 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) RRM_6 PF14259.1 KII94156.1 - 4.6e-11 42.5 0.0 1e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII94156.1 - 1.2e-09 37.6 0.0 2.9e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94156.1 - 0.00028 20.6 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4139 PF13598.1 KII94158.1 - 0.052 12.8 0.6 0.11 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) MAPEG PF01124.13 KII94160.1 - 3e-20 72.1 0.6 3.7e-20 71.8 0.4 1.1 1 0 0 1 1 1 1 MAPEG family WD40 PF00400.27 KII94161.1 - 3.2e-24 83.8 11.5 2.1e-08 33.6 0.2 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KII94161.1 - 9.1e-18 63.9 0.0 2.8e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 KII94161.1 - 1e-05 25.3 0.2 0.00023 20.9 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KII94161.1 - 0.0057 14.5 0.1 0.028 12.2 0.0 1.9 1 1 0 2 2 2 1 IKI3 family Nucleoplasmin PF03066.10 KII94161.1 - 6.5 6.2 14.9 0.047 13.2 1.1 2.4 2 0 0 2 2 2 0 Nucleoplasmin PA28_beta PF02252.13 KII94162.1 - 1.4e-39 134.9 0.5 2.2e-39 134.3 0.4 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 KII94162.1 - 1.3e-06 28.4 0.5 3.5e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit DUF3591 PF12157.3 KII94163.1 - 4e-181 602.4 0.3 6.2e-181 601.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KII94163.1 - 0.00011 21.7 3.1 0.00024 20.6 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Homeobox_KN PF05920.6 KII94163.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain zf-C2H2 PF00096.21 KII94164.1 - 1.6e-07 31.2 16.7 9.4e-05 22.5 0.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 KII94164.1 - 0.0031 17.6 5.0 0.028 14.6 0.2 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KII94164.1 - 0.0043 17.2 4.4 0.0043 17.2 3.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KII94164.1 - 0.015 15.4 0.1 0.015 15.4 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KII94164.1 - 0.019 15.2 1.1 0.019 15.2 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger F-box PF00646.28 KII94170.1 - 4.8e-06 26.0 0.6 3.4e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII94170.1 - 5.6e-06 25.9 0.1 2.1e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like Med7 PF05983.6 KII94172.1 - 1.9e-27 96.0 0.0 2.4e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 MED7 protein RdRP_4 PF02123.11 KII94172.1 - 0.039 12.6 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase AMP-binding PF00501.23 KII94173.1 - 4.5e-80 269.0 0.0 5.7e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII94173.1 - 9.2e-12 45.7 0.6 4.7e-11 43.4 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Drc1-Sld2 PF11719.3 KII94175.1 - 3.8e-16 59.2 0.6 3.8e-16 59.2 0.4 2.9 1 1 1 2 2 2 1 DNA replication and checkpoint protein Pal1 PF08316.6 KII94176.1 - 0.0082 16.5 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Pal1 cell morphology protein PCI PF01399.22 KII94179.1 - 5.9e-18 65.1 0.1 5.5e-17 61.9 0.0 2.5 2 1 0 2 2 2 1 PCI domain MRP-S25 PF13741.1 KII94180.1 - 1.4e-48 165.3 3.8 1.3e-47 162.2 2.7 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 zf-met PF12874.2 KII94181.1 - 1.5e-06 28.1 1.2 2.7e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KII94181.1 - 0.017 14.3 0.6 0.031 13.5 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like S1 PF00575.18 KII94182.1 - 1e-61 204.9 20.8 5.9e-13 48.6 0.2 10.7 10 0 0 10 10 10 10 S1 RNA binding domain TPR_16 PF13432.1 KII94182.1 - 1.9e-08 34.7 0.0 0.011 16.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII94182.1 - 1.3e-06 28.5 0.0 3.8 8.4 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII94182.1 - 2.3e-06 27.4 1.5 0.1 12.5 0.0 4.0 2 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII94182.1 - 8.4e-05 22.8 0.0 0.094 13.0 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII94182.1 - 0.0019 17.8 0.0 0.0076 15.8 0.0 2.0 1 1 1 2 2 2 2 TPR repeat TPR_21 PF09976.4 KII94182.1 - 0.0021 17.9 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KII94182.1 - 0.0055 16.8 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KII94182.1 - 0.0087 15.1 1.1 0.34 9.9 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.9 KII94182.1 - 0.012 15.4 8.3 0.068 12.9 0.0 3.9 1 1 1 4 4 4 0 Suppressor of forked protein (Suf) TPR_6 PF13174.1 KII94182.1 - 0.025 14.9 0.1 6.4 7.4 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KII94182.1 - 0.036 13.8 0.5 0.46 10.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII94182.1 - 0.072 13.0 2.1 10 6.3 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KII94182.1 - 0.085 13.1 0.0 2.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII94182.1 - 0.24 11.0 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_3 PF13415.1 KII94183.1 - 1.7e-41 139.4 8.9 7.1e-10 38.7 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KII94183.1 - 4.2e-31 106.3 3.8 8.2e-07 28.8 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KII94183.1 - 6.6e-31 105.8 15.6 1.2e-07 31.4 0.1 7.1 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KII94183.1 - 1.8e-30 103.8 1.4 1.6e-07 31.2 0.2 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KII94183.1 - 2.3e-27 94.2 0.1 4.3e-06 26.1 0.3 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KII94183.1 - 2e-22 78.0 12.3 0.0013 18.4 0.2 6.7 6 1 0 6 6 6 5 Kelch motif DUF4200 PF13863.1 KII94183.1 - 0.01 15.7 3.1 0.01 15.7 2.2 9.2 6 3 2 9 9 9 0 Domain of unknown function (DUF4200) RAG2 PF03089.9 KII94183.1 - 0.37 9.4 1.9 10 4.7 0.0 3.3 3 1 1 4 4 4 0 Recombination activating protein 2 Reo_sigmaC PF04582.7 KII94183.1 - 1.1 8.4 31.1 0.02 14.0 1.6 4.6 3 2 1 4 4 4 0 Reovirus sigma C capsid protein Esterase PF00756.15 KII94185.1 - 3.2e-40 138.1 0.0 3.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KII94185.1 - 4.6e-05 23.2 0.0 7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII94185.1 - 0.0013 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.4 KII94185.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Pkinase PF00069.20 KII94186.1 - 2.1e-52 177.8 0.0 3.4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94186.1 - 1.8e-30 105.8 0.0 2.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII94186.1 - 0.00097 18.1 0.0 0.0025 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FHA PF00498.21 KII94186.1 - 0.0045 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 KII94186.1 - 0.059 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1 PF01926.18 KII94187.1 - 1.3e-15 57.3 0.1 1.9e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII94187.1 - 8.2e-05 21.9 0.1 0.00041 19.6 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KII94187.1 - 0.00014 21.1 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KII94187.1 - 0.00072 18.7 0.1 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KII94187.1 - 0.033 14.6 0.1 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KII94187.1 - 0.059 13.1 0.1 0.059 13.1 0.1 2.2 3 0 0 3 3 3 0 Dynamin family cobW PF02492.14 KII94187.1 - 0.13 11.6 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vfa1 PF08432.5 KII94187.1 - 1.1 9.2 9.6 0.22 11.5 3.6 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KII94187.1 - 8.9 4.2 11.5 15 3.5 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cellulase PF00150.13 KII94188.1 - 9.5e-46 156.2 0.0 1.1e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HNH_2 PF13391.1 KII94191.1 - 0.0056 16.4 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease Methyltransf_23 PF13489.1 KII94192.1 - 5.5e-08 32.6 0.0 9.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII94192.1 - 2.7e-05 24.5 0.0 5.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII94192.1 - 3.8e-05 23.9 0.0 7.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII94192.1 - 0.00039 20.8 0.0 0.00094 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII94192.1 - 0.00048 19.7 0.0 0.0015 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KII94192.1 - 0.0018 17.3 0.0 0.0073 15.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KII94192.1 - 0.0041 17.6 0.0 0.013 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KII94192.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase DNA_pol_B_palm PF14792.1 KII94194.1 - 6.3e-27 93.8 0.0 2.3e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KII94194.1 - 3.1e-19 68.2 0.3 1.2e-17 63.1 0.2 2.8 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KII94194.1 - 3.5e-19 68.2 0.0 8.7e-19 66.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KII94194.1 - 2.2e-17 62.9 0.2 1.1e-16 60.7 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KII94194.1 - 0.0025 17.9 0.1 3 8.0 0.0 3.3 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH PF00633.18 KII94194.1 - 0.0058 16.2 0.1 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.18 KII94194.1 - 0.0066 16.7 0.0 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Cellulase PF00150.13 KII94195.1 - 3.6e-49 167.4 0.0 4.4e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KII94195.1 - 9.7e-14 50.7 7.7 2.2e-13 49.5 5.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Complex1_LYR PF05347.10 KII94196.1 - 0.0036 17.0 6.0 0.0036 17.0 4.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII94196.1 - 0.021 15.0 3.6 0.051 13.7 2.5 1.7 1 0 0 1 1 1 0 Complex1_LYR-like Sec8_exocyst PF04048.9 KII94197.1 - 2.2e-34 118.1 0.7 4.7e-34 117.0 0.5 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KII94197.1 - 4.6e-07 29.0 0.8 4.6e-07 29.0 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2305 PF10230.4 KII94198.1 - 9.6e-48 162.9 0.0 1.1e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KII94198.1 - 6.6e-08 32.6 1.4 9.3e-08 32.2 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII94198.1 - 0.0013 18.5 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KII94198.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) DUF900 PF05990.7 KII94198.1 - 0.024 13.9 0.3 0.66 9.2 0.0 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KII94198.1 - 0.035 13.6 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein SNF2_N PF00176.18 KII94199.1 - 5.1e-63 212.6 0.4 7.4e-63 212.1 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KII94199.1 - 1.1e-20 73.6 0.2 2.3e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KII94199.1 - 6.3e-14 51.6 0.0 1.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 KII94199.1 - 9.9e-09 34.7 3.7 1.2e-05 24.6 0.1 3.1 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain DEAD PF00270.24 KII94199.1 - 0.00038 19.9 0.0 0.00092 18.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.19 KII94199.1 - 0.058 13.0 0.1 0.058 13.0 0.1 3.7 4 0 0 4 4 4 0 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KII94199.1 - 0.12 12.0 10.6 0.36 10.5 0.1 3.9 4 0 0 4 4 4 0 PHD-finger UPF0014 PF03649.8 KII94200.1 - 1.6e-41 142.1 9.9 2.8e-41 141.3 6.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 KII94200.1 - 3.9 7.2 19.2 0.059 13.1 4.1 3.2 1 1 1 2 2 2 0 FtsX-like permease family DUF4231 PF14015.1 KII94200.1 - 7.7 6.5 0.0 7.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Ribosomal_S4 PF00163.14 KII94201.1 - 9.8e-28 96.3 0.8 2.2e-27 95.2 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KII94201.1 - 1.7e-12 46.5 0.9 1.7e-12 46.5 0.6 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 KII94202.1 - 2.1e-38 130.0 3.0 3.6e-38 129.3 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Surface_Ag_2 PF01617.12 KII94202.1 - 0.071 12.3 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Surface antigen RNA_replicase_B PF03431.8 KII94202.1 - 0.098 10.8 0.3 0.12 10.6 0.2 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain Lipase_GDSL_2 PF13472.1 KII94203.1 - 1.6e-11 44.7 0.0 2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KII94203.1 - 0.00017 21.5 0.1 0.0031 17.3 0.1 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1399 PF07173.7 KII94204.1 - 7.3e-22 78.1 0.1 3e-18 66.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) Ribonuclease_T2 PF00445.13 KII94205.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease T2 family TIP49 PF06068.8 KII94207.1 - 2.5e-178 592.8 2.5 2.9e-178 592.6 1.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KII94207.1 - 6.4e-09 36.0 0.3 8.5e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KII94207.1 - 8.8e-07 28.2 1.7 0.002 17.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KII94207.1 - 0.00014 20.8 0.3 0.00028 19.8 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KII94207.1 - 0.00058 20.0 0.1 0.19 11.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KII94207.1 - 0.00079 19.4 0.0 0.0069 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KII94207.1 - 0.0026 17.2 0.1 0.0056 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KII94207.1 - 0.0026 16.9 2.3 0.049 12.7 0.3 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KII94207.1 - 0.011 15.6 0.1 2.1 8.2 0.0 3.1 3 2 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KII94207.1 - 0.012 15.3 0.2 5.2 6.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1212 PF06738.7 KII94210.1 - 4.7e-30 104.5 3.6 4.7e-30 104.5 2.5 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KII94210.1 - 5.4e-16 58.7 10.5 5.4e-16 58.7 7.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) SNF2_N PF00176.18 KII94211.1 - 1.1e-71 241.0 0.0 3.5e-71 239.4 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII94211.1 - 1.4e-11 44.1 0.0 2.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KII94211.1 - 2.5e-05 23.9 2.3 5.6e-05 22.7 1.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 KII94211.1 - 0.0034 17.2 0.0 0.72 9.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KII94211.1 - 0.0091 15.6 2.7 0.026 14.1 1.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII94211.1 - 0.12 12.4 3.1 0.28 11.2 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dsrm PF00035.20 KII94212.1 - 1.1e-08 35.5 0.2 2.5e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KII94212.1 - 8.8e-08 32.1 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KII94212.1 - 0.024 15.0 0.0 0.052 14.0 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease III domain MARVEL PF01284.18 KII94213.1 - 7.5e-08 32.3 9.5 1.1e-07 31.8 6.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Oxidored_q3 PF00499.15 KII94213.1 - 0.89 9.3 5.6 9.2 6.0 3.9 2.1 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 LysM PF01476.15 KII94214.1 - 3e-12 46.2 0.0 4.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 LysM domain Malic_M PF03949.10 KII94215.1 - 1.1e-76 257.7 0.0 1.4e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KII94215.1 - 6.5e-62 208.3 0.0 9.2e-62 207.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NTP_transf_2 PF01909.18 KII94216.1 - 1.4e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 KII94216.1 - 0.0026 17.6 0.4 0.005 16.7 0.3 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DAP PF15228.1 KII94217.1 - 0.023 15.4 2.0 0.094 13.4 1.4 1.9 1 1 0 1 1 1 0 Death-associated protein PAP_assoc PF03828.14 KII94218.1 - 3.8e-08 33.1 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KII94218.1 - 0.037 14.3 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain TBD PF12845.2 KII94218.1 - 0.14 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 TBD domain Ribosomal_L28e PF01778.12 KII94219.1 - 2.1e-30 105.5 0.0 2.7e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family F-box-like PF12937.2 KII94220.1 - 0.00015 21.4 0.1 0.00072 19.2 0.0 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII94220.1 - 0.00019 21.0 0.5 0.00062 19.3 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box PF00646.28 KII94221.1 - 0.00034 20.1 0.8 0.001 18.6 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII94221.1 - 0.004 16.8 2.8 0.0048 16.6 0.2 2.5 3 0 0 3 3 3 1 F-box-like RRM_1 PF00076.17 KII94222.1 - 5e-25 86.9 0.0 2.1e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94222.1 - 1.9e-18 66.1 0.0 2e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94222.1 - 6.2e-17 61.1 0.0 1.9e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KII94222.1 - 0.0027 17.3 0.0 0.068 12.9 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 BTB_2 PF02214.17 KII94223.1 - 7.8e-05 22.8 0.0 0.0017 18.5 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Big_1 PF02369.11 KII94223.1 - 0.057 13.3 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) ACOX PF01756.14 KII94224.1 - 2.6e-28 98.6 0.0 6.8e-28 97.3 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KII94224.1 - 8.3e-12 45.4 0.0 1.5e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KII94224.1 - 2.1e-06 27.1 0.4 6e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KII94224.1 - 0.00031 20.8 1.0 0.00063 19.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_33 PF13671.1 KII94225.1 - 6.3e-16 58.5 0.1 5.6e-14 52.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain RNA_ligase PF09414.5 KII94225.1 - 4.9e-10 39.5 0.0 7.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 RNA ligase Y_phosphatase PF00102.22 KII94225.1 - 8.8e-07 28.4 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KII94225.1 - 3.4e-05 24.1 0.0 6.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KII94225.1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KII94225.1 - 0.00048 19.7 0.0 0.0015 18.0 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 KII94225.1 - 0.00082 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KII94225.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_22 PF13401.1 KII94225.1 - 0.029 14.4 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PfkB PF00294.19 KII94226.1 - 3.3e-67 226.7 0.8 3.7e-67 226.5 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KII94226.1 - 0.012 14.8 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase DEC-1_C PF04626.8 KII94226.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region zf-C2H2_4 PF13894.1 KII94227.1 - 8.3e-11 41.4 5.2 2.9e-05 24.0 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KII94227.1 - 3.3e-09 36.5 4.1 0.00073 19.7 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KII94227.1 - 0.00038 20.5 3.3 0.091 12.9 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KII94227.1 - 0.008 16.0 2.2 0.017 15.0 0.3 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII94227.1 - 0.017 15.3 9.9 0.04 14.2 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain GAGA PF09237.6 KII94227.1 - 0.076 12.6 1.1 0.16 11.5 0.7 1.5 1 0 0 1 1 1 0 GAGA factor zf-met PF12874.2 KII94227.1 - 0.081 13.1 0.6 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type YdjO PF14169.1 KII94227.1 - 0.51 9.8 2.3 0.63 9.5 0.3 1.9 2 0 0 2 2 2 0 Cold-inducible protein YdjO Raptor_N PF14538.1 KII94228.1 - 4.3e-62 208.5 0.0 1.1e-61 207.1 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KII94228.1 - 3.9e-12 45.5 2.8 4.6e-06 26.3 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 KII94228.1 - 4.5e-06 26.2 0.2 0.00025 20.8 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 KII94228.1 - 0.0002 21.5 0.0 0.0011 19.2 0.0 2.3 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KII94228.1 - 0.0012 19.3 0.0 0.012 16.1 0.0 2.9 1 1 0 1 1 1 1 HEAT-like repeat BBS2_Mid PF14783.1 KII94228.1 - 0.17 11.7 0.2 1.1 9.0 0.0 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Dynactin PF12455.3 KII94229.1 - 7.2e-88 294.0 2.6 7.2e-88 294.0 1.8 3.4 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 KII94229.1 - 4.4e-22 77.5 1.3 7.2e-22 76.8 0.6 1.6 2 0 0 2 2 2 1 CAP-Gly domain TMF_DNA_bd PF12329.3 KII94229.1 - 0.0079 15.9 2.7 0.0079 15.9 1.9 10.0 7 4 4 11 11 11 3 TATA element modulatory factor 1 DNA binding TraF_2 PF13729.1 KII94229.1 - 8 5.1 10.6 6.6 5.4 0.4 3.0 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein RCC1 PF00415.13 KII94230.1 - 3.4e-24 84.7 11.5 9.1e-05 22.5 0.2 8.7 7 3 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII94230.1 - 3.5e-14 51.9 24.8 0.00029 20.3 0.4 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RdRP PF05183.7 KII94231.1 - 2.1e-99 333.7 0.0 2.7e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Chitin_synth_2 PF03142.10 KII94232.1 - 1.2e-278 924.8 0.0 1.6e-278 924.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KII94232.1 - 4.1e-16 59.2 0.7 1.2e-15 57.7 0.5 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KII94232.1 - 2.5e-12 47.1 0.1 1.9e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KII94232.1 - 0.00045 19.5 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KII94232.1 - 0.043 13.4 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Nop10p PF04135.7 KII94233.1 - 8.4e-22 76.6 0.1 9.6e-22 76.4 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Pyridox_oxase_2 PF12766.2 KII94235.1 - 2.4e-22 79.1 0.0 3.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KII94235.1 - 3.9e-05 23.5 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CorA PF01544.13 KII94236.1 - 8.6e-35 120.1 8.6 7.8e-30 103.9 5.9 2.9 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Thioredoxin PF00085.15 KII94237.1 - 1.5e-25 88.9 0.0 1.7e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KII94237.1 - 2.2e-05 24.6 0.1 0.0012 19.0 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII94237.1 - 2.5e-05 24.3 0.0 0.00014 21.8 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KII94237.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII94237.1 - 0.0024 17.4 0.1 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 KII94237.1 - 0.0057 16.2 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KII94237.1 - 0.033 14.2 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.19 KII94237.1 - 0.035 14.0 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.15 KII94238.1 - 3.2e-27 94.2 0.0 3.7e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KII94238.1 - 6.7e-09 35.9 0.1 5.3e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII94238.1 - 1.6e-07 31.3 0.0 3.2e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KII94238.1 - 2.1e-06 27.3 0.1 5.3e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KII94238.1 - 6.2e-06 25.9 0.0 6.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KII94238.1 - 7e-06 25.6 0.0 8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KII94238.1 - 0.0022 17.9 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 KII94238.1 - 0.0039 16.7 0.0 0.0049 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 KII94238.1 - 0.0055 16.6 0.1 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF4131 PF13567.1 KII94239.1 - 0.15 11.4 1.8 0.15 11.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PBP1_TM PF14812.1 KII94240.1 - 0.33 11.2 1.4 0.36 11.1 0.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 KII94242.1 - 3.2e-60 203.4 0.0 3.3e-36 124.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII94242.1 - 1.4e-25 89.8 0.0 6e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KII94242.1 - 0.003 16.6 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.19 KII94242.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 PX domain Pkinase_C PF00433.19 KII94242.1 - 0.0069 16.8 13.5 0.0069 16.8 9.4 4.1 3 1 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 KII94242.1 - 0.034 13.1 0.0 0.56 9.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Hs1pro-1_C PF07014.7 KII94242.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus GRAM PF02893.15 KII94243.1 - 1.3e-16 59.8 0.0 3.3e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 GRAM domain ABC_tran PF00005.22 KII94244.1 - 2.9e-50 170.1 0.0 1.1e-23 84.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KII94244.1 - 7e-25 87.7 44.9 7.7e-16 58.0 15.3 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KII94244.1 - 1e-21 78.1 1.6 7.7e-07 29.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain ABC2_membrane PF01061.19 KII94244.1 - 3.1e-06 26.4 11.0 3.1e-06 26.4 7.6 4.2 4 0 0 4 4 4 2 ABC-2 type transporter AAA_23 PF13476.1 KII94244.1 - 5.3e-06 26.8 2.6 0.00077 19.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KII94244.1 - 1.8e-05 24.1 1.6 0.022 14.2 0.3 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KII94244.1 - 0.00016 20.9 1.0 6.4 5.9 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KII94244.1 - 0.0058 15.7 0.0 1.4 7.8 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain DUF4162 PF13732.1 KII94244.1 - 0.017 15.6 0.0 4.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_30 PF13604.1 KII94244.1 - 0.017 14.7 1.1 9.1 5.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 KII94244.1 - 0.047 12.8 0.9 3.8 6.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Yae1_N PF09811.4 KII94246.1 - 2.3e-10 39.8 4.8 3.5e-10 39.2 3.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cu_amine_oxid PF01179.15 KII94247.1 - 1.3e-155 518.2 0.0 1.5e-155 517.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KII94247.1 - 1.7e-14 53.6 0.0 3.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KII94247.1 - 8.7e-06 25.7 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_9 PF13371.1 KII94248.1 - 0.00069 19.4 2.5 0.00089 19.0 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C2H2 PF00096.21 KII94250.1 - 7.8e-11 41.6 13.3 6.1e-06 26.2 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII94250.1 - 6.5e-07 29.2 11.0 0.0055 16.9 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII94250.1 - 2.5e-05 24.3 13.7 0.00015 21.8 4.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KII94252.1 - 2.5e-11 43.2 9.6 3.2e-05 24.0 1.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII94252.1 - 2.2e-08 33.8 9.4 0.00019 21.4 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII94252.1 - 2.6e-05 24.2 4.9 2.6e-05 24.2 3.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KII94252.1 - 0.00039 20.2 0.6 0.00039 20.2 0.4 2.0 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2457 PF10446.4 KII94252.1 - 0.65 8.6 9.3 0.22 10.1 4.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2457) Med25_VWA PF11265.3 KII94253.1 - 0.22 10.5 0.9 0.41 9.6 0.7 1.6 1 1 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A EF-hand_1 PF00036.27 KII94254.1 - 1.7e-24 83.1 17.3 1.4e-09 36.5 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KII94254.1 - 4.3e-22 78.0 14.0 3.4e-12 46.2 3.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KII94254.1 - 2.4e-20 70.5 14.4 9e-09 34.4 0.2 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KII94254.1 - 1e-15 57.0 17.9 1.7e-09 37.1 1.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KII94254.1 - 1.3e-15 55.9 12.1 7.4e-06 25.0 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KII94254.1 - 7.5e-10 38.5 1.0 0.00099 18.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KII94254.1 - 4.3e-08 32.8 5.2 0.00059 19.5 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 KII94254.1 - 0.00021 20.9 0.4 0.0051 16.3 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein SPARC_Ca_bdg PF10591.4 KII94254.1 - 0.029 14.4 4.0 0.48 10.4 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3164 PF11363.3 KII94254.1 - 0.035 13.4 0.9 0.82 9.0 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3164) TerB PF05099.8 KII94254.1 - 0.051 13.2 1.5 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Tellurite resistance protein TerB MgtE_N PF03448.12 KII94254.1 - 1.1 9.5 5.2 0.37 11.1 0.8 2.2 3 0 0 3 3 3 0 MgtE intracellular N domain zf-C2H2 PF00096.21 KII94255.1 - 5.1e-13 48.5 47.3 0.013 15.8 0.5 8.3 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-met PF12874.2 KII94255.1 - 9.2e-12 44.7 29.8 0.003 17.7 0.6 7.4 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KII94255.1 - 3.5e-09 36.5 38.0 0.0006 19.8 2.0 6.8 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KII94255.1 - 8.9e-09 35.0 45.6 0.077 13.3 0.6 7.8 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KII94255.1 - 3.8e-05 23.7 29.8 0.0021 18.1 8.5 4.3 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KII94255.1 - 0.0022 17.8 35.1 0.097 12.6 0.1 7.6 8 0 0 8 8 8 4 C2H2-type zinc finger DZR PF12773.2 KII94255.1 - 0.029 14.1 17.8 16 5.4 7.5 4.2 2 1 0 2 2 2 0 Double zinc ribbon DUF4187 PF13821.1 KII94255.1 - 0.057 13.0 0.1 0.057 13.0 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4187) FYVE PF01363.16 KII94255.1 - 2.6 8.0 28.1 0.48 10.3 11.2 3.8 2 2 0 2 2 2 0 FYVE zinc finger Swi5 PF07061.6 KII94256.1 - 6.2e-17 61.1 0.7 7.2e-17 60.9 0.5 1.0 1 0 0 1 1 1 1 Swi5 Macoilin PF09726.4 KII94256.1 - 0.026 12.8 0.4 0.029 12.6 0.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3008 PF11450.3 KII94256.1 - 0.059 13.5 1.1 0.098 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) DUF4140 PF13600.1 KII94256.1 - 0.084 13.3 1.8 0.14 12.5 1.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.1 KII94256.1 - 0.092 12.8 0.6 0.13 12.4 0.4 1.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF904 PF06005.7 KII94256.1 - 0.12 12.7 0.4 0.16 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF1090 PF06476.7 KII94256.1 - 0.17 11.5 2.7 0.22 11.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Mito_carr PF00153.22 KII94257.1 - 1.9e-54 181.3 0.7 6.9e-19 67.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PXA PF02194.10 KII94258.1 - 7.2e-44 149.5 0.5 1.6e-43 148.4 0.0 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KII94258.1 - 2.6e-30 104.8 0.5 1.5e-29 102.3 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KII94258.1 - 1.5e-18 66.6 0.0 5e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KII94258.1 - 5.2e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gcd10p PF04189.8 KII94259.1 - 1.7e-72 244.0 0.0 2.7e-71 240.1 0.0 2.2 1 1 0 1 1 1 1 Gcd10p family Menin PF05053.8 KII94259.1 - 0.11 10.7 0.6 0.16 10.1 0.4 1.2 1 0 0 1 1 1 0 Menin zf-MYND PF01753.13 KII94262.1 - 0.038 13.8 0.5 0.038 13.8 0.3 2.1 2 0 0 2 2 2 0 MYND finger UNC45-central PF11701.3 KII94263.1 - 6.5e-13 48.6 0.0 2.6e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Myosin_head PF00063.16 KII94264.1 - 5.2e-227 755.2 0.4 8.4e-227 754.5 0.3 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KII94264.1 - 2.2e-41 141.3 0.0 3.6e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 KII94264.1 - 4.3e-11 42.2 0.2 9.1e-11 41.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII94264.1 - 1.2e-10 40.7 0.0 3.1e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII94264.1 - 4.5e-09 35.5 1.0 8.9e-09 34.6 0.7 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 KII94264.1 - 6e-05 23.1 0.2 0.00015 21.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 KII94264.1 - 0.0072 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KII94264.1 - 0.026 13.6 0.0 0.066 12.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 KII94264.1 - 0.064 12.5 0.9 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SH3_4 PF06347.8 KII94264.1 - 0.064 12.8 0.2 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_17 PF13207.1 KII94264.1 - 0.072 13.9 0.0 0.23 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII94264.1 - 0.081 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KII94264.1 - 0.18 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Lum_binding PF00677.12 KII94266.1 - 1.5e-31 108.1 0.0 1.4e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain DAO PF01266.19 KII94267.1 - 5.5e-21 74.8 3.6 2.3e-20 72.8 2.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII94267.1 - 0.0076 16.2 0.1 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KII94267.1 - 0.02 15.2 0.3 0.045 14.1 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KII94267.1 - 0.054 13.2 0.4 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KII94267.1 - 0.075 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KII94267.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain zf-RING_2 PF13639.1 KII94268.1 - 2.1e-13 49.8 4.4 2.1e-13 49.8 3.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KII94268.1 - 7.7e-11 41.9 0.6 7.7e-11 41.9 0.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KII94268.1 - 5e-07 29.3 3.6 5e-07 29.3 2.5 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII94268.1 - 1.1e-06 28.1 2.5 1.1e-06 28.1 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII94268.1 - 1.4e-06 27.8 3.9 1.4e-06 27.8 2.7 2.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII94268.1 - 3.3e-06 27.0 1.8 3.3e-06 27.0 1.2 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII94268.1 - 8.5e-06 25.5 0.6 1.8e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 KII94268.1 - 1.9e-05 24.5 5.5 2.1e-05 24.4 1.7 2.4 2 0 0 2 2 2 1 zinc-finger FANCL_C PF11793.3 KII94268.1 - 0.0048 16.8 3.4 0.041 13.8 2.3 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KII94268.1 - 0.12 12.1 2.6 0.39 10.4 0.6 2.4 1 1 1 2 2 2 0 RING-type zinc-finger HypA PF01155.14 KII94268.1 - 1.2 8.8 4.2 14 5.4 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PHD PF00628.24 KII94268.1 - 5.6 6.7 15.6 0.57 9.9 3.0 2.7 3 0 0 3 3 3 0 PHD-finger zf-TFIIB PF13453.1 KII94268.1 - 7.6 5.8 10.3 16 4.8 1.6 3.6 3 1 1 4 4 4 0 Transcription factor zinc-finger Prok-RING_1 PF14446.1 KII94268.1 - 9.3 6.0 12.2 1.7 8.4 3.6 3.0 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 ABC_tran PF00005.22 KII94269.1 - 1.1e-51 174.7 0.0 6.9e-30 104.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII94269.1 - 2.7e-44 151.6 12.0 7.9e-23 81.2 3.3 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KII94269.1 - 6.4e-09 35.3 4.4 0.0011 18.2 1.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KII94269.1 - 6.5e-09 35.0 0.3 0.0025 16.7 0.0 2.5 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KII94269.1 - 7.8e-09 35.7 0.7 0.0023 17.9 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 KII94269.1 - 3.7e-08 32.7 0.3 0.0046 16.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KII94269.1 - 2.3e-07 30.5 0.0 0.0043 16.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 KII94269.1 - 3.7e-07 29.7 0.0 0.018 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KII94269.1 - 1.3e-06 28.8 0.8 0.00078 19.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KII94269.1 - 1.1e-05 25.0 0.1 0.076 12.4 0.1 3.0 3 1 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 KII94269.1 - 2.1e-05 24.6 0.6 0.54 10.4 0.3 3.1 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 KII94269.1 - 4e-05 23.5 0.6 0.0088 15.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KII94269.1 - 8.5e-05 23.0 0.0 0.42 11.1 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KII94269.1 - 0.00013 22.7 0.0 0.14 12.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII94269.1 - 0.00032 19.8 0.1 0.14 11.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 KII94269.1 - 0.00064 19.4 0.1 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KII94269.1 - 0.00065 18.4 0.0 0.63 8.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KII94269.1 - 0.00068 19.3 0.2 0.8 9.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KII94269.1 - 0.00078 19.7 0.0 0.24 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KII94269.1 - 0.0011 19.0 2.4 2.2 8.1 0.0 4.1 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.1 KII94269.1 - 0.0022 17.7 0.8 0.34 10.6 0.0 3.7 3 0 0 3 3 3 1 Part of AAA domain MMR_HSR1 PF01926.18 KII94269.1 - 0.0024 17.8 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KII94269.1 - 0.0033 16.6 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KII94269.1 - 0.0036 17.1 0.3 0.95 9.3 0.2 2.8 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 KII94269.1 - 0.004 16.4 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein AAA PF00004.24 KII94269.1 - 0.0047 17.1 2.4 6.8 6.8 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KII94269.1 - 0.0057 16.1 0.4 0.38 10.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KII94269.1 - 0.0066 16.0 0.5 0.74 9.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KII94269.1 - 0.0069 15.3 1.4 0.47 9.3 0.0 2.8 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KII94269.1 - 0.0094 15.0 0.1 0.76 8.8 0.0 2.8 3 0 0 3 3 3 1 KaiC Dynamin_N PF00350.18 KII94269.1 - 0.017 14.9 0.7 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.12 KII94269.1 - 0.019 14.3 0.0 2.5 7.4 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.24 KII94269.1 - 0.024 14.1 0.9 9.9 5.6 0.0 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase CbiA PF01656.18 KII94269.1 - 0.03 13.7 0.0 8.5 5.7 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.7 KII94269.1 - 0.055 12.9 0.1 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SbcCD_C PF13558.1 KII94269.1 - 0.086 12.7 0.6 11 5.9 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 KII94269.1 - 0.089 12.4 0.0 2.5 7.7 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 KII94269.1 - 0.13 12.4 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KII94269.1 - 0.15 10.8 0.2 1 8.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 KII94269.1 - 0.16 11.5 0.0 14 5.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KII94269.1 - 0.16 11.7 0.0 25 4.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RTA1 PF04479.8 KII94270.1 - 3.5e-42 144.4 7.3 4.5e-42 144.0 5.0 1.1 1 0 0 1 1 1 1 RTA1 like protein PetG PF02529.10 KII94270.1 - 0.01 15.3 0.7 0.025 14.1 0.5 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF89 PF01937.14 KII94275.1 - 4.9e-106 354.5 0.1 6e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 AAA_13 PF13166.1 KII94276.1 - 0.0003 19.4 23.0 0.0003 19.4 16.0 7.8 2 1 5 7 7 7 3 AAA domain IncA PF04156.9 KII94276.1 - 0.0019 17.8 19.7 0.0019 17.8 13.7 11.9 3 3 8 12 12 12 5 IncA protein GAS PF13851.1 KII94276.1 - 0.0023 17.1 9.0 0.0023 17.1 6.2 12.0 5 4 8 13 13 13 2 Growth-arrest specific micro-tubule binding DUF830 PF05708.7 KII94276.1 - 0.57 10.1 6.1 0.11 12.5 0.1 2.9 3 0 0 3 3 3 0 Orthopoxvirus protein of unknown function (DUF830) Lgl_C PF08596.5 KII94277.1 - 2.3e-35 121.8 0.0 8.9e-35 119.8 0.0 2.0 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KII94277.1 - 5.1e-07 29.3 0.1 0.0016 18.2 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KII94277.1 - 0.0019 17.0 0.0 0.57 8.8 0.0 2.9 3 0 0 3 3 3 2 Nup133 N terminal like Hepar_II_III PF07940.8 KII94278.1 - 8.4e-09 35.3 0.4 2e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 Heparinase II/III-like protein Rick_17kDa_Anti PF05433.10 KII94278.1 - 0.88 9.2 6.8 2.2 8.0 4.7 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain cEGF PF12662.2 KII94279.1 - 0.0079 15.8 0.4 0.0079 15.8 0.3 2.5 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KII94279.1 - 8.7 6.5 11.7 45 4.2 8.1 2.1 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site UBN2_3 PF14244.1 KII94280.1 - 0.0022 17.5 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KII94280.1 - 0.0061 16.1 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NPBW PF15180.1 KII94285.1 - 0.55 9.8 6.2 0.23 11.0 1.1 2.3 2 0 0 2 2 2 0 Neuropeptides B and W zf-C2H2_jaz PF12171.3 KII94286.1 - 6.1e-16 58.0 18.7 0.0032 17.5 0.1 6.7 4 1 2 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII94286.1 - 4.7e-13 48.8 23.5 0.035 14.3 0.5 8.4 8 1 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KII94286.1 - 1e-11 44.4 42.5 0.021 15.1 1.2 7.8 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KII94286.1 - 4.8e-10 38.9 24.3 0.0007 19.4 1.1 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KII94286.1 - 1.2e-09 37.7 41.1 0.12 12.7 0.1 8.0 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KII94286.1 - 0.0016 18.5 27.4 0.61 10.2 4.0 5.1 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.1 KII94286.1 - 0.019 14.5 2.9 0.019 14.5 2.0 4.1 5 0 0 5 5 5 0 Probable zinc-binding domain zf-TFIIB PF13453.1 KII94286.1 - 0.037 13.2 6.5 0.69 9.1 0.0 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.1 KII94286.1 - 0.051 13.8 0.0 0.051 13.8 0.0 6.9 8 0 0 8 8 8 0 Zinc-finger double domain Nudix_N_2 PF14803.1 KII94286.1 - 0.083 12.5 0.6 0.083 12.5 0.4 4.5 6 0 0 6 6 6 0 Nudix N-terminal zf-SNAP50_C PF12251.3 KII94286.1 - 0.26 10.6 13.9 3 7.1 1.2 2.4 1 1 2 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal Peptidase_M16 PF00675.15 KII94287.1 - 1.7e-39 134.9 0.0 2.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KII94287.1 - 2.5e-34 118.5 0.0 5.3e-33 114.2 0.0 2.6 2 1 0 2 2 2 1 Peptidase M16 inactive domain OTCace_N PF02729.16 KII94287.1 - 0.086 12.5 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain BRCA-2_OB1 PF09103.5 KII94288.1 - 9.3e-28 96.3 0.0 1.5e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 KII94288.1 - 2.4e-06 27.2 0.1 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical Cellulase PF00150.13 KII94290.1 - 2.5e-12 46.5 3.8 6.8e-11 41.8 2.6 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UDPGP PF01704.13 KII94291.1 - 3.7e-47 160.7 0.0 4.9e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KII94291.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Taxilin PF09728.4 KII94292.1 - 1.4e-14 53.8 34.4 2.5e-07 30.0 4.3 2.5 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 KII94292.1 - 4.8e-06 26.1 0.7 0.032 13.9 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Tht1 PF04163.7 KII94292.1 - 0.79 8.0 4.2 1.2 7.4 2.9 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein LRR_4 PF12799.2 KII94293.1 - 0.093 12.3 0.3 0.4 10.3 0.2 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KII94293.1 - 0.12 12.1 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat HIT PF01230.18 KII94295.1 - 1.4e-25 89.6 0.1 1.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KII94295.1 - 3.6e-07 30.4 0.0 5.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Monellin PF09200.5 KII94295.1 - 0.04 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Monellin DUF2217 PF10265.4 KII94298.1 - 2.1 6.9 8.3 2.5 6.7 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TauD PF02668.11 KII94299.1 - 6.7e-51 173.4 0.1 8.8e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_47 PF01532.15 KII94300.1 - 5.3e-148 493.4 0.0 6.2e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.18 KII94301.1 - 2.5e-10 40.5 0.3 6.1e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KII94301.1 - 0.012 15.4 5.6 0.026 14.4 3.9 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger DUF2180 PF09947.4 KII94301.1 - 0.12 12.1 0.5 0.28 10.9 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Enolase_C PF00113.17 KII94303.1 - 7.2e-148 491.3 0.1 9.8e-148 490.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KII94303.1 - 3.6e-57 191.9 0.1 5.8e-57 191.2 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KII94303.1 - 6.7e-06 26.0 0.1 1.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KII94303.1 - 0.00045 19.2 0.1 0.001 18.1 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KII94303.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain NGP1NT PF08153.7 KII94304.1 - 5.6e-46 155.7 0.0 1.2e-45 154.6 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KII94304.1 - 3.6e-20 72.0 0.0 4.4e-16 58.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KII94304.1 - 3.2e-05 23.2 0.3 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KII94304.1 - 0.00013 21.4 0.6 0.025 13.9 0.1 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KII94304.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 KII94304.1 - 0.0086 15.3 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family YbfN PF13982.1 KII94304.1 - 0.055 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 YbfN-like lipoprotein Dynamin_N PF00350.18 KII94304.1 - 0.18 11.6 5.6 2.4 7.9 0.0 3.8 3 1 1 4 4 4 0 Dynamin family CDC45 PF02724.9 KII94304.1 - 3.5 5.5 10.3 5.4 4.9 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S15 PF00312.17 KII94305.1 - 6e-19 67.6 0.1 1.1e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 rve_3 PF13683.1 KII94305.1 - 0.048 13.1 0.8 0.12 11.9 0.6 1.6 1 0 0 1 1 1 0 Integrase core domain DUF1685 PF07939.6 KII94305.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) IBN_N PF03810.14 KII94307.1 - 1.2e-06 28.2 1.2 0.00087 19.1 0.1 4.6 3 2 1 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.17 KII94307.1 - 1.6e-05 24.5 0.2 0.0061 16.5 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat ParcG PF10274.4 KII94307.1 - 5.7e-05 23.0 0.1 0.34 10.8 0.0 3.5 3 0 0 3 3 3 2 Parkin co-regulated protein HEAT_2 PF13646.1 KII94307.1 - 7.4e-05 22.9 6.5 0.00029 21.0 0.0 4.9 4 1 2 6 6 6 1 HEAT repeats Adaptin_N PF01602.15 KII94307.1 - 0.00032 19.1 0.3 0.0025 16.2 0.1 2.4 3 0 0 3 3 3 1 Adaptin N terminal region Cse1 PF08506.5 KII94307.1 - 0.00042 18.9 0.0 0.00085 17.9 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_EZ PF13513.1 KII94307.1 - 0.00049 20.5 9.9 7.7 7.1 0.0 7.4 9 0 0 9 9 9 1 HEAT-like repeat Xpo1 PF08389.7 KII94307.1 - 0.00052 19.9 0.1 0.0088 15.9 0.0 3.3 2 1 0 2 2 2 1 Exportin 1-like protein CAS_CSE1 PF03378.10 KII94307.1 - 0.0071 14.7 0.0 0.035 12.4 0.0 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Urb2 PF10441.4 KII94307.1 - 0.019 14.5 0.0 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 Urb2/Npa2 family TRI5 PF06330.6 KII94309.1 - 1.3e-19 70.1 0.1 1.8e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KII94309.1 - 0.056 12.6 0.6 2.3 7.3 0.4 2.2 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain TPR_11 PF13414.1 KII94310.1 - 1.2e-14 53.6 8.1 7.8e-14 51.0 2.4 2.9 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 KII94310.1 - 4.8e-06 25.9 6.8 4.3e-05 22.9 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KII94310.1 - 3.1e-05 23.5 0.4 3.1e-05 23.5 0.3 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII94310.1 - 4.4e-05 24.0 3.6 4.4e-05 24.0 2.5 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII94310.1 - 5.1e-05 22.7 0.2 0.0057 16.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KII94310.1 - 0.00032 20.5 12.3 0.0037 17.1 2.3 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KII94310.1 - 0.00068 19.9 1.2 0.00068 19.9 0.8 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII94310.1 - 0.0019 18.6 8.5 0.0022 18.4 0.2 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KII94310.1 - 0.002 18.1 5.2 1.8 8.9 0.2 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat API5 PF05918.6 KII94310.1 - 0.0045 15.5 7.8 0.0075 14.8 5.4 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) TPR_9 PF13371.1 KII94310.1 - 0.0086 15.9 2.3 0.1 12.4 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.2 KII94310.1 - 0.048 13.7 1.0 0.082 12.9 0.7 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 KII94310.1 - 0.061 13.2 4.1 2.8 7.8 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KII94310.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.8 3 1 1 4 4 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KII94310.1 - 0.41 10.8 8.7 0.048 13.7 1.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCCH PF00642.19 KII94310.1 - 0.44 10.2 11.4 0.15 11.7 0.7 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII94310.1 - 1.5 8.9 10.8 0.62 10.1 1.7 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DASH_Ask1 PF08655.5 KII94311.1 - 2.2e-08 33.7 0.0 4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Lipase_GDSL PF00657.17 KII94312.1 - 0.0001 22.2 2.9 0.00015 21.6 2.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.19 KII94314.1 - 8.1e-123 410.3 18.2 9.3e-123 410.1 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII94314.1 - 1.7e-18 66.4 42.1 5.7e-17 61.4 10.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.12 KII94314.1 - 1.9 8.0 5.3 0.96 9.0 1.6 2.0 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Mid2 PF04478.7 KII94316.1 - 0.01 15.2 0.1 0.01 15.2 0.0 4.1 3 2 2 5 5 5 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KII94316.1 - 0.059 12.6 0.2 0.059 12.6 0.1 3.2 3 0 0 3 3 3 0 Transmembrane alpha-helix domain FAM163 PF15069.1 KII94316.1 - 6.3 7.3 12.2 8.9 6.8 0.0 3.7 3 1 0 3 3 3 0 FAM163 family G-alpha PF00503.15 KII94317.1 - 2.1e-128 428.3 0.0 2.6e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII94317.1 - 4.6e-15 55.2 0.1 6.1e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KII94317.1 - 0.0022 17.4 0.0 0.0064 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KII94317.1 - 0.0093 15.4 0.3 0.21 11.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KII94317.1 - 0.012 14.8 0.6 4.7 6.2 0.1 2.8 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KII94317.1 - 0.038 14.1 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 KII94317.1 - 0.09 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ribonuc_L-PSP PF01042.16 KII94318.1 - 1.5e-41 140.9 0.2 1.7e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Proteasome PF00227.21 KII94319.1 - 1.3e-57 194.2 0.0 1.6e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII94319.1 - 2e-14 52.5 0.0 3.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Inositol_P PF00459.20 KII94320.1 - 1.4e-66 224.5 0.0 1.6e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Aldo_ket_red PF00248.16 KII94321.1 - 1.7e-51 174.7 0.0 2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dor1 PF04124.7 KII94322.1 - 9.5e-52 175.5 0.0 2e-50 171.2 0.0 2.1 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 KII94322.1 - 0.002 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 KII94322.1 - 0.0037 17.0 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 B56 PF01603.15 KII94322.1 - 0.046 12.3 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PE PF00934.15 KII94322.1 - 4.4 7.4 10.5 0.15 12.1 0.4 2.9 3 0 0 3 3 3 0 PE family Toxin_7 PF05980.7 KII94323.1 - 0.21 11.6 6.2 0.46 10.5 0.3 2.8 2 0 0 2 2 2 0 Toxin 7 F-box-like PF12937.2 KII94324.1 - 2.9e-07 30.0 0.4 6e-07 29.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 KII94325.1 - 8.7e-12 44.5 5.3 6.6e-10 38.4 0.1 3.5 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 KII94325.1 - 1.8e-06 27.2 0.5 0.21 11.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII94325.1 - 1.3e-05 24.7 4.5 0.018 14.9 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KII94325.1 - 0.00022 21.0 0.0 0.0055 16.5 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Orbi_NS3 PF01616.11 KII94325.1 - 0.018 13.9 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 Orbivirus NS3 Dus PF01207.12 KII94326.1 - 9.6e-48 162.5 0.0 1.8e-47 161.7 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Radical_SAM PF04055.16 KII94326.1 - 0.061 13.4 0.1 0.4 10.8 0.1 2.2 2 1 0 2 2 2 0 Radical SAM superfamily Asp PF00026.18 KII94327.1 - 9.5e-78 261.6 11.8 1.2e-77 261.3 8.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KII94327.1 - 4.7e-07 29.5 0.1 4.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KII94327.1 - 1.9e-05 24.7 4.6 6.6e-05 22.9 1.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TTL PF03133.10 KII94329.1 - 1e-40 139.5 0.0 1.5e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KII94329.1 - 0.0002 21.1 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF2404 PF10296.4 KII94330.1 - 1.6e-08 34.5 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Abhydrolase_6 PF12697.2 KII94331.1 - 3.5e-06 27.0 0.1 5.3e-06 26.4 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII94331.1 - 3.1e-05 23.7 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family GldM_N PF12081.3 KII94332.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Mpp10 PF04006.7 KII94333.1 - 7e-95 318.6 70.7 1e-77 261.9 16.8 2.5 1 1 2 3 3 3 2 Mpp10 protein Dermcidin PF15291.1 KII94333.1 - 6.1 7.0 11.6 0.23 11.6 1.7 3.1 3 0 0 3 3 3 0 Dermcidin, antibiotic peptide SNARE PF05739.14 KII94334.1 - 1.5e-06 27.8 0.3 1.5e-06 27.8 0.2 3.2 4 1 1 5 5 5 1 SNARE domain V-SNARE_C PF12352.3 KII94334.1 - 0.0018 18.3 3.2 0.32 11.0 0.3 2.9 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec34 PF04136.10 KII94334.1 - 0.41 10.3 1.9 1 9.0 0.2 2.0 2 0 0 2 2 2 0 Sec34-like family Transformer PF06495.6 KII94334.1 - 0.44 10.3 8.2 1.3 8.8 5.7 1.7 1 1 0 1 1 1 0 Fruit fly transformer protein MAD PF05557.8 KII94335.1 - 0.0057 14.8 0.1 0.0074 14.4 0.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein FlaC_arch PF05377.6 KII94335.1 - 0.072 12.9 0.4 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) SAD_SRA PF02182.12 KII94336.1 - 6.6e-38 129.4 0.0 1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain SSP160 PF06933.6 KII94339.1 - 0.004 15.2 17.7 0.0041 15.1 12.3 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 UPF0160 PF03690.8 KII94340.1 - 2.3e-129 431.3 0.0 2.7e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) MARVEL PF01284.18 KII94341.1 - 0.0054 16.5 10.3 0.0079 16.0 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain AGTRAP PF06396.6 KII94342.1 - 0.026 14.2 1.7 0.11 12.1 1.2 1.9 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Glyco_transf_41 PF13844.1 KII94343.1 - 1.6e-70 237.4 4.4 3.9e-43 147.0 0.1 4.0 3 1 0 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 KII94343.1 - 8e-13 47.8 0.5 4.5e-07 29.4 0.0 4.0 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 KII94343.1 - 1.6e-11 43.3 0.0 0.0023 17.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KII94343.1 - 1.2e-09 37.5 0.0 0.00036 20.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KII94343.1 - 2.2e-09 37.1 0.0 2.8e-05 23.9 0.0 3.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII94343.1 - 6.3e-07 28.8 0.0 0.012 15.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII94343.1 - 3.4e-06 26.4 0.0 0.0038 16.8 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII94343.1 - 4.4e-05 22.9 0.1 0.082 12.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KII94343.1 - 6.2e-05 22.7 0.2 0.058 13.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KII94343.1 - 0.00047 20.5 0.5 0.42 11.3 0.0 4.4 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII94343.1 - 0.0018 18.8 0.0 0.069 13.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII94343.1 - 0.011 16.1 0.1 0.41 11.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.1 KII94343.1 - 0.092 12.8 0.2 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 zf-DNL PF05180.7 KII94346.1 - 0.058 13.1 0.2 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 DNL zinc finger Aldose_epim PF01263.15 KII94347.1 - 2.6e-31 108.8 0.0 2.9e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.1 KII94347.1 - 0.014 13.9 0.0 0.017 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) cEGF PF12662.2 KII94348.1 - 0.00014 21.4 1.3 0.00014 21.4 0.9 3.0 3 0 0 3 3 3 1 Complement Clr-like EGF-like zf-met PF12874.2 KII94350.1 - 1e-06 28.7 25.8 0.14 12.4 0.1 6.7 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KII94350.1 - 0.00087 19.3 6.8 0.00087 19.3 4.7 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KII94350.1 - 0.0077 16.5 37.8 0.29 11.5 0.3 7.0 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII94350.1 - 0.046 14.0 35.9 0.54 10.7 0.1 6.9 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII94350.1 - 0.11 12.6 0.6 0.11 12.6 0.4 6.1 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KII94350.1 - 0.2 11.9 0.1 0.2 11.9 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc-finger domain ABC_tran PF00005.22 KII94351.1 - 6.4e-47 159.3 0.0 9.7e-23 80.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KII94351.1 - 6.5e-39 133.2 46.0 1.5e-23 83.1 10.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 KII94351.1 - 1.9e-15 57.5 4.8 0.0018 18.2 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_25 PF13481.1 KII94351.1 - 4e-09 36.1 0.4 0.0056 16.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KII94351.1 - 7.2e-08 31.7 2.6 0.00011 21.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KII94351.1 - 1.6e-07 30.7 1.4 0.014 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KII94351.1 - 1.5e-06 29.0 0.4 0.026 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KII94351.1 - 1.1e-05 25.4 2.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KII94351.1 - 2.6e-05 23.5 0.0 0.052 12.7 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 KII94351.1 - 3.2e-05 23.6 0.3 1.2 8.8 0.0 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KII94351.1 - 3.5e-05 23.9 0.4 0.29 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KII94351.1 - 8.5e-05 22.4 0.1 0.23 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KII94351.1 - 0.00012 21.8 0.1 0.39 10.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KII94351.1 - 0.00034 20.3 1.0 0.098 12.4 0.2 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KII94351.1 - 0.0005 20.0 1.6 0.66 9.9 0.6 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KII94351.1 - 0.0013 19.0 0.9 0.14 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KII94351.1 - 0.0014 18.9 2.0 0.32 11.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KII94351.1 - 0.0024 18.3 1.8 1.5 9.3 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 KII94351.1 - 0.0079 15.8 0.5 6.1 6.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KII94351.1 - 0.011 15.3 0.2 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KII94351.1 - 0.011 15.1 0.2 0.16 11.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 KII94351.1 - 0.018 14.1 0.0 24 3.7 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain IstB_IS21 PF01695.12 KII94351.1 - 0.039 13.3 0.4 6.2 6.2 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KII94351.1 - 0.075 13.2 0.6 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KII94351.1 - 0.11 12.3 0.1 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KII94351.1 - 0.14 11.8 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 KII94351.1 - 0.17 11.5 1.0 2 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KII94351.1 - 0.19 11.9 0.3 8.6 6.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KII94351.1 - 0.22 10.5 0.5 0.77 8.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 KII94351.1 - 0.29 10.5 3.9 3.4 7.0 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KII94351.1 - 0.35 10.8 3.0 7.8 6.4 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 KII94351.1 - 0.39 10.1 4.2 6.7 6.1 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KII94351.1 - 0.43 10.0 0.7 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KII94351.1 - 0.48 9.9 1.4 6.3 6.2 0.2 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 KII94351.1 - 0.8 8.3 0.1 8 5.0 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF87 PF01935.12 KII94351.1 - 2.2 8.0 4.4 13 5.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 PRK PF00485.13 KII94351.1 - 2.2 7.7 3.5 28 4.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family F-box-like PF12937.2 KII94353.1 - 0.0017 18.0 4.9 0.0074 15.9 3.4 2.2 1 1 0 1 1 1 1 F-box-like HEAT PF02985.17 KII94354.1 - 1.8e-44 145.8 16.7 0.00097 19.0 0.0 13.6 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 KII94354.1 - 3.1e-31 107.5 12.1 2.6e-08 34.0 0.0 7.4 2 2 4 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KII94354.1 - 1.3e-12 47.9 0.4 0.0097 16.2 0.0 7.4 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KII94354.1 - 9.8e-08 30.7 3.2 0.00095 17.6 0.5 3.8 2 2 2 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 KII94354.1 - 2.2e-07 31.1 21.0 1.4 9.5 0.0 9.7 7 4 3 10 10 10 3 HEAT-like repeat Cnd1 PF12717.2 KII94354.1 - 1.3e-06 28.3 0.0 7.9e-05 22.5 0.0 3.5 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KII94354.1 - 0.00024 20.8 9.6 2.5 8.0 0.0 6.6 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 KII94354.1 - 0.02 13.1 3.0 0.066 11.4 0.1 2.7 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KII94354.1 - 0.069 13.6 5.6 3.2 8.4 0.1 6.0 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat Tic20 PF09685.5 KII94356.1 - 1.5e-06 28.1 1.4 2e-06 27.7 1.0 1.1 1 0 0 1 1 1 1 Tic20-like protein HTH_43 PF09904.4 KII94356.1 - 0.069 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Ribosomal_S24e PF01282.14 KII94357.1 - 4.5e-34 116.1 0.0 6.7e-34 115.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Actin PF00022.14 KII94358.1 - 3.2e-134 447.2 0.0 3.7e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KII94358.1 - 0.026 13.1 0.0 0.27 9.7 0.0 2.1 2 1 0 2 2 2 0 MreB/Mbl protein GPI2 PF06432.6 KII94361.1 - 7.3e-85 284.7 10.2 8.2e-85 284.5 7.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase bZIP_1 PF00170.16 KII94363.1 - 0.00012 21.9 5.6 0.00046 20.0 3.9 2.0 1 1 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 KII94363.1 - 0.013 15.7 0.5 0.024 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KII94363.1 - 0.029 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Lzipper-MIP1 PF14389.1 KII94363.1 - 0.12 12.4 1.3 2.5 8.2 0.3 2.3 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.6 KII94363.1 - 0.73 9.6 7.1 0.067 13.0 1.5 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 KII94363.1 - 8 6.3 11.6 0.14 12.0 0.6 2.9 2 1 1 3 3 3 0 Basic region leucine zipper Apc4 PF12896.2 KII94364.1 - 1.7e-32 112.4 0.0 3.4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DEAD PF00270.24 KII94365.1 - 3.4e-46 156.8 0.1 8e-45 152.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94365.1 - 2.9e-24 84.7 0.0 8.9e-24 83.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KIP1 PF07765.7 KII94365.1 - 0.018 14.8 0.4 0.049 13.4 0.3 1.7 1 0 0 1 1 1 0 KIP1-like protein AAA_22 PF13401.1 KII94365.1 - 0.053 13.6 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain CENP-T PF15511.1 KII94365.1 - 0.28 10.3 37.9 0.57 9.3 5.8 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T APH PF01636.18 KII94366.1 - 4.5e-05 23.2 0.1 0.00054 19.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KII94366.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.9 KII94366.1 - 0.11 11.5 0.2 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_16 PF00722.16 KII94367.1 - 6.1e-12 45.2 0.1 1.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SurE PF01975.12 KII94368.1 - 2.7e-39 134.5 0.0 3.3e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE RasGEF PF00617.14 KII94369.1 - 3.1e-29 102.0 0.0 5.9e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KII94369.1 - 1e-08 35.1 0.0 3.6e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 KII94369.1 - 3.1e-05 23.4 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KII94369.1 - 4.9e-05 23.8 0.0 0.00015 22.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII94369.1 - 0.0019 17.4 0.0 0.091 11.9 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Viral_helicase1 PF01443.13 KII94369.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KII94369.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KII94369.1 - 0.038 13.8 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KII94369.1 - 0.055 13.6 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4212 PF13937.1 KII94370.1 - 0.13 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Ribosomal_L15e PF00827.12 KII94371.1 - 1.9e-89 298.2 11.6 2.2e-89 298.0 8.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 MFS_1 PF07690.11 KII94372.1 - 5.5e-21 74.6 21.6 8.5e-20 70.7 13.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.15 KII94372.1 - 0.00069 18.3 1.2 0.00069 18.3 0.8 3.2 3 1 1 4 4 4 2 Phosphate transporter family Lipase_3 PF01764.20 KII94373.1 - 1.6e-22 79.6 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KII94373.1 - 4.4e-05 23.4 1.2 7e-05 22.8 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII94373.1 - 0.001 18.8 0.1 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KII94373.1 - 0.041 13.1 0.2 0.63 9.2 0.2 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KII94373.1 - 0.15 11.5 0.2 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HSCB_C PF07743.8 KII94374.1 - 9.9e-15 54.7 2.0 2e-14 53.7 0.5 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KII94374.1 - 9.4e-08 31.6 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 KII94374.1 - 0.03 14.1 0.8 0.056 13.2 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KII94374.1 - 4.3 6.6 6.6 8.6 5.7 4.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MFS_1 PF07690.11 KII94376.1 - 3.7e-38 131.1 24.3 3.7e-38 131.1 16.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII94376.1 - 2e-16 59.6 6.2 2e-16 59.6 4.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.27 KII94377.1 - 5.7e-05 22.8 13.0 0.17 11.8 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Adaptin_N PF01602.15 KII94378.1 - 3.3e-123 411.8 7.0 4.4e-123 411.3 4.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KII94378.1 - 1.7e-38 131.0 0.0 3.4e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KII94378.1 - 3.9e-19 69.0 0.0 8.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HA2 PF04408.18 KII94379.1 - 1.1e-18 67.1 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KII94379.1 - 9.8e-13 47.7 0.0 2.1e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 KII94379.1 - 9.1e-08 32.5 0.0 0.00074 20.0 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 KII94379.1 - 1.8e-07 30.8 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KII94379.1 - 8.5e-06 25.5 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Pex24p PF06398.6 KII94380.1 - 2.9e-10 39.4 0.3 4.1e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin F-box-like PF12937.2 KII94381.1 - 0.00062 19.4 0.3 0.00062 19.4 0.2 2.3 2 0 0 2 2 2 1 F-box-like CMV_US PF08001.6 KII94381.1 - 0.059 12.4 0.1 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 CMV US NUDIX PF00293.23 KII94382.1 - 5.7e-25 87.5 0.0 7.9e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.8 KII94383.1 - 2.1e-23 82.4 0.0 3.7e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KII94383.1 - 4.1e-11 41.8 0.0 8e-11 40.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KII94383.1 - 0.03 13.8 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 ScpA/B protein DUF3292 PF11696.3 KII94384.1 - 1e-09 36.8 4.9 7.9e-09 33.9 0.4 3.2 2 1 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 KII94384.1 - 0.0032 16.9 0.2 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 KII94384.1 - 0.13 11.8 2.2 15 5.1 0.8 2.4 2 0 0 2 2 2 0 Reticulon INCENP_ARK-bind PF03941.10 KII94385.1 - 3.6e-17 61.9 0.4 3.6e-17 61.9 0.3 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region DCP2 PF05026.8 KII94386.1 - 5.1e-36 122.4 2.1 9.9e-36 121.5 1.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KII94386.1 - 4.5e-15 55.4 0.0 8.8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Mrr_N PF14338.1 KII94387.1 - 0.034 14.2 0.3 0.096 12.7 0.2 1.7 1 0 0 1 1 1 0 Mrr N-terminal domain AATF-Che1 PF13339.1 KII94387.1 - 0.069 13.3 4.0 0.077 13.1 0.8 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor SBP PF03110.9 KII94388.1 - 0.37 11.0 11.6 0.088 13.0 5.3 2.0 2 0 0 2 2 2 0 SBP domain F-box-like PF12937.2 KII94389.1 - 4.7e-07 29.4 0.4 9.2e-07 28.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII94389.1 - 4.2e-06 26.2 0.2 8.1e-06 25.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain zf-CHCC PF10276.4 KII94390.1 - 2.2e-16 59.3 1.7 3.4e-16 58.7 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain Lamp PF01299.12 KII94390.1 - 0.74 8.9 6.3 0.94 8.5 4.4 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Sporozoite_P67 PF05642.6 KII94390.1 - 3.9 5.2 5.1 4.6 4.9 3.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 KII94391.1 - 2.2e-57 194.1 0.0 5.2e-57 192.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94391.1 - 9.3e-24 83.8 0.0 2.8e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase SpoIIIAH PF12685.2 KII94391.1 - 0.64 9.4 7.1 1.4 8.4 4.9 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Pribosyltran_N PF13793.1 KII94392.1 - 1.8e-43 146.9 0.8 2.8e-42 143.1 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KII94392.1 - 5.3e-36 124.0 1.8 1.8e-30 106.0 0.9 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KII94392.1 - 2.6e-12 46.5 0.8 1.4e-11 44.2 0.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KII94392.1 - 0.00063 18.9 0.2 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 KII94392.1 - 0.44 10.2 4.5 0.14 11.8 0.3 2.2 3 0 0 3 3 3 0 Chlorosome envelope protein C UbiA PF01040.13 KII94393.1 - 1.8e-25 89.6 23.4 3.5e-25 88.7 16.2 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.2 KII94394.1 - 6.8e-09 35.3 0.4 1.3e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII94394.1 - 3.3e-07 29.7 0.3 6.3e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KII94394.1 - 0.33 10.7 1.3 0.51 10.0 0.1 2.0 3 0 0 3 3 3 0 F-box-like domain AAA_2 PF07724.9 KII94395.1 - 3.1e-49 167.1 0.0 1.1e-45 155.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KII94395.1 - 7.8e-25 86.5 0.1 3e-24 84.7 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KII94395.1 - 2.3e-24 86.0 0.0 1.1e-13 51.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 KII94395.1 - 1.7e-17 63.0 8.2 2.1e-13 49.9 0.6 4.5 4 0 0 4 4 4 2 Clp amino terminal domain AAA_5 PF07728.9 KII94395.1 - 2.7e-14 53.0 0.1 2.3e-07 30.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KII94395.1 - 4.1e-11 43.1 0.0 0.00064 19.8 0.0 4.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KII94395.1 - 4.6e-11 43.0 4.3 0.00013 22.0 0.0 4.9 4 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 KII94395.1 - 7.6e-08 32.0 0.0 0.00013 21.4 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KII94395.1 - 2.2e-07 30.4 0.0 0.00064 19.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KII94395.1 - 5.9e-07 29.8 0.0 0.0029 17.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KII94395.1 - 7.1e-06 25.3 0.1 0.012 14.7 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KII94395.1 - 4.7e-05 24.2 9.4 0.053 14.3 2.4 4.1 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KII94395.1 - 5.9e-05 22.7 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 KII94395.1 - 6.2e-05 22.1 0.0 0.021 13.9 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KII94395.1 - 7.5e-05 22.4 0.3 0.45 10.2 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_33 PF13671.1 KII94395.1 - 0.00013 21.8 0.0 0.17 11.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII94395.1 - 0.00026 21.1 0.2 1.4 9.0 0.0 2.8 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.7 KII94395.1 - 0.00032 20.3 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KII94395.1 - 0.002 18.1 0.4 1.1 9.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain PhoH PF02562.11 KII94395.1 - 0.0097 15.1 0.0 0.83 8.8 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein ABC_tran PF00005.22 KII94395.1 - 0.01 16.1 1.1 3.1 8.1 0.0 3.3 3 0 0 3 3 3 0 ABC transporter OmpH PF03938.9 KII94395.1 - 0.016 15.1 6.4 0.011 15.6 1.9 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Arch_ATPase PF01637.13 KII94395.1 - 0.021 14.5 6.1 0.75 9.4 0.1 4.5 4 1 1 5 5 5 0 Archaeal ATPase MobB PF03205.9 KII94395.1 - 0.023 14.4 0.0 2.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KII94395.1 - 0.024 14.1 0.0 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 KII94395.1 - 0.042 13.0 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Torsin PF06309.6 KII94395.1 - 0.065 13.1 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Torsin UPF0079 PF02367.12 KII94395.1 - 0.07 12.7 0.0 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 KII94395.1 - 0.073 12.4 0.6 6 6.2 0.0 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KII94395.1 - 0.11 11.8 2.7 8.8 5.6 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KII94395.1 - 0.47 9.8 3.9 9.8 5.5 0.0 3.6 3 1 0 3 3 3 0 AAA-like domain IncA PF04156.9 KII94395.1 - 0.58 9.7 6.9 1.2 8.6 4.8 1.5 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KII94395.1 - 1.4 7.9 6.2 2.5 7.0 4.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 KII94396.1 - 1.2e-74 250.7 0.0 1.5e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94396.1 - 1.2e-36 126.1 0.0 2e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII94396.1 - 0.00095 18.2 0.0 0.0022 17.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII94396.1 - 0.0081 15.5 0.0 0.099 11.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KII94396.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family MafB19-deam PF14437.1 KII94396.1 - 0.27 10.8 3.9 6.2 6.4 0.7 2.2 2 0 0 2 2 2 0 MafB19-like deaminase DUF4230 PF14014.1 KII94396.1 - 0.28 11.0 2.3 0.46 10.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) CITED PF04487.7 KII94396.1 - 0.99 9.5 10.9 1.5 9.0 7.5 1.2 1 0 0 1 1 1 0 CITED TFIIA PF03153.8 KII94396.1 - 7.3 6.3 9.2 9.8 5.9 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 KII94397.1 - 1.1e-74 250.9 0.0 1.3e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94397.1 - 8.7e-37 126.5 0.0 1.5e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII94397.1 - 0.00037 19.5 0.0 0.00082 18.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KII94397.1 - 0.0032 16.8 0.1 0.048 13.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KII94397.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF4230 PF14014.1 KII94397.1 - 1.2 8.9 4.0 2 8.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) CITED PF04487.7 KII94397.1 - 1.3 9.1 13.6 1.9 8.6 9.5 1.2 1 0 0 1 1 1 0 CITED DUF4407 PF14362.1 KII94397.1 - 5.9 5.7 7.8 8.9 5.1 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.8 KII94397.1 - 7 6.4 11.3 9.5 6.0 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp12 PF04003.7 KII94398.1 - 1.2e-13 50.9 0.5 5.1e-13 48.9 0.4 1.9 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KII94398.1 - 3.2e-07 29.9 2.6 0.0036 17.1 0.6 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat TFIIA PF03153.8 KII94398.1 - 6.4 6.5 15.4 5.6 6.7 9.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fapy_DNA_glyco PF01149.19 KII94399.1 - 8.1e-25 87.4 0.1 1.4e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KII94399.1 - 7.1e-22 76.9 0.0 1.1e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KII94399.1 - 0.022 13.2 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) MFS_1 PF07690.11 KII94400.1 - 1.6e-51 175.1 30.6 1.5e-34 119.2 4.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KII94400.1 - 0.00012 21.7 0.4 0.088 12.6 0.0 3.3 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.15 KII94400.1 - 0.006 14.6 0.8 0.006 14.6 0.6 2.5 2 1 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.11 KII94400.1 - 0.25 10.8 7.9 0.021 14.3 1.3 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PAT1 PF09770.4 KII94401.1 - 0.16 10.1 3.1 0.23 9.6 2.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HATPase_c PF02518.21 KII94402.1 - 6.4e-28 96.6 0.1 1.7e-27 95.3 0.0 1.8 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KII94402.1 - 2.5e-22 78.9 0.0 3.5e-19 68.8 0.0 2.9 2 0 0 2 2 2 2 Response regulator receiver domain AAA_16 PF13191.1 KII94402.1 - 1.1e-16 61.3 0.5 6.4e-16 58.8 0.3 2.5 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.20 KII94402.1 - 2.5e-15 56.1 1.1 1e-14 54.2 0.0 2.8 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 KII94402.1 - 6e-10 38.7 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 KII94402.1 - 6.4e-10 39.2 0.0 2e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 KII94402.1 - 1.7e-09 38.3 0.0 5.1e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 KII94402.1 - 1.1e-07 31.2 0.0 2.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.1 KII94402.1 - 0.001 19.2 0.6 0.032 14.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain TPR_12 PF13424.1 KII94402.1 - 0.0036 17.1 1.1 0.13 12.2 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat HATPase_c_3 PF13589.1 KII94402.1 - 0.0089 15.6 0.0 0.04 13.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF815 PF05673.8 KII94402.1 - 0.025 13.5 0.0 0.056 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KII94402.1 - 0.056 13.1 0.2 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 KII94403.1 - 3e-36 124.4 0.1 5.4e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94403.1 - 1.2e-24 85.9 0.0 6.2e-24 83.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII94403.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 KII94404.1 - 6.2e-57 189.3 0.1 7.5e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_ab_N PF02874.18 KII94404.1 - 0.012 15.7 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain Glyco_hydro_43 PF04616.9 KII94405.1 - 1.1e-16 60.8 5.5 1.7e-16 60.1 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KII94405.1 - 0.064 13.4 12.5 0.16 12.0 8.6 1.7 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) WD40 PF00400.27 KII94406.1 - 8.9e-13 47.5 0.7 0.00016 21.3 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Rax2 PF12768.2 KII94406.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RNB PF00773.14 KII94407.1 - 7.4e-92 308.0 0.2 1.5e-91 307.1 0.0 1.6 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 KII94407.1 - 6e-09 36.0 0.0 2e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 KII94407.1 - 0.052 13.0 1.2 0.44 10.0 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Peptidase_M20 PF01546.23 KII94407.1 - 0.063 12.7 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 His_Phos_2 PF00328.17 KII94408.1 - 8.8e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 KII94409.1 - 1.1e-63 214.8 0.0 1.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94409.1 - 2.2e-23 82.6 0.0 2.9e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII94409.1 - 3.2e-05 23.0 0.0 7.9e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like BRF1 PF07741.8 KII94409.1 - 8.1 6.7 7.2 36 4.6 0.1 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Ribosomal_L19e PF01280.15 KII94410.1 - 8.5e-61 204.0 10.9 8.5e-61 204.0 7.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 KII94410.1 - 0.04 13.3 0.0 0.18 11.2 0.0 2.1 1 0 0 1 1 1 0 S4 domain DUF349 PF03993.7 KII94410.1 - 0.8 9.9 8.2 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Formyl_trans_N PF00551.14 KII94411.1 - 1.4e-40 138.7 0.0 1.7e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase MOZ_SAS PF01853.13 KII94412.1 - 2.8e-65 219.1 0.0 8.5e-64 214.2 0.0 2.1 2 0 0 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 KII94412.1 - 6.6e-07 28.9 0.4 1.3e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain SKG6 PF08693.5 KII94413.1 - 0.0012 18.1 0.7 0.002 17.4 0.5 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 KII94413.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Pkinase PF00069.20 KII94414.1 - 2.9e-58 197.0 0.0 3.8e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94414.1 - 1.5e-26 92.9 0.0 2.1e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII94414.1 - 2.4e-07 30.7 0.2 6.6e-05 22.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KII94414.1 - 4.8e-06 25.7 0.0 7.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 KII94414.1 - 2.1e-05 24.9 0.0 5.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 KII94414.1 - 3.8e-05 22.8 0.0 7.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII94414.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family bZIP_Maf PF03131.12 KII94414.1 - 0.11 12.8 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor CS PF04969.11 KII94415.1 - 1.2e-09 38.5 0.0 5.8e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 CS domain Metallophos PF00149.23 KII94415.1 - 0.00036 19.9 0.0 0.00087 18.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII94415.1 - 0.12 12.2 0.0 0.93 9.3 0.0 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain C2 PF00168.25 KII94416.1 - 6.6e-15 54.7 0.0 2.5e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain Cul7 PF11515.3 KII94416.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 VIT1 PF01988.14 KII94416.1 - 0.11 12.0 0.1 11 5.4 0.0 2.2 2 0 0 2 2 2 0 VIT family Vps35 PF03635.12 KII94417.1 - 0 1055.2 0.0 0 1055.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 VHS PF00790.14 KII94418.1 - 1e-41 141.8 1.9 5.1e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KII94418.1 - 5.5e-17 61.4 6.4 9.1e-17 60.7 4.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KII94418.1 - 0.017 15.0 3.0 0.035 13.9 2.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger UIM PF02809.15 KII94418.1 - 0.054 13.0 20.9 0.028 13.9 2.2 3.5 4 0 0 4 4 4 0 Ubiquitin interaction motif PHA-1 PF06542.6 KII94418.1 - 0.054 12.1 0.1 0.081 11.6 0.1 1.2 1 0 0 1 1 1 0 Regulator protein PHA-1 WHIM3 PF15614.1 KII94418.1 - 0.093 12.5 0.0 0.3 10.8 0.0 2.0 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 HypA PF01155.14 KII94418.1 - 0.096 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KII94418.1 - 0.81 9.5 6.6 26 4.7 4.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon RNA_pol_Rpb1_1 PF04997.7 KII94419.1 - 3.3e-116 388.2 0.0 4.5e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KII94419.1 - 1.7e-106 355.4 0.0 2.5e-106 354.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 KII94419.1 - 1.2e-71 240.3 0.0 2.3e-71 239.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 KII94419.1 - 5.6e-68 228.0 0.0 1e-67 227.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KII94419.1 - 4.2e-50 169.5 0.0 1.1e-49 168.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KII94419.1 - 4.4e-41 139.7 0.0 8.2e-41 138.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KII94419.1 - 4.6e-35 119.6 0.0 1e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KII94419.1 - 0.0017 18.3 203.2 0.079 13.1 7.1 14.3 8 2 8 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat ABC_tran PF00005.22 KII94420.1 - 2.4e-38 131.5 0.0 2.4e-24 86.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KII94420.1 - 2.1e-37 129.0 24.9 1.7e-21 76.8 2.7 4.2 3 1 0 3 3 3 2 ABC transporter transmembrane region AAA_25 PF13481.1 KII94420.1 - 7.7e-07 28.6 0.0 0.045 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KII94420.1 - 1.5e-05 25.0 0.2 0.18 11.7 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KII94420.1 - 4.7e-05 23.8 0.3 0.0031 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KII94420.1 - 0.00012 22.2 3.3 0.24 11.3 0.0 4.1 2 2 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KII94420.1 - 0.00026 20.4 1.1 0.95 9.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KII94420.1 - 0.0004 19.6 2.7 0.87 8.7 0.0 4.1 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 KII94420.1 - 0.00096 19.6 0.0 3.1 8.3 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein Adeno_IVa2 PF02456.10 KII94420.1 - 0.0025 16.5 0.1 0.014 14.0 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_5 PF07728.9 KII94420.1 - 0.0056 16.4 1.0 1.4 8.6 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 KII94420.1 - 0.0065 15.4 0.1 0.67 8.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KII94420.1 - 0.0072 16.4 0.2 0.68 10.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KII94420.1 - 0.011 15.6 0.2 1 9.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 KII94420.1 - 0.012 14.8 0.2 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 KII94420.1 - 0.013 15.2 0.5 0.49 10.0 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KII94420.1 - 0.016 14.7 0.1 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KII94420.1 - 0.016 16.0 0.5 6.5 7.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KII94420.1 - 0.017 14.5 0.2 0.64 9.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KII94420.1 - 0.024 14.8 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KII94420.1 - 0.031 14.1 1.1 0.098 12.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 KII94420.1 - 0.086 13.1 0.0 24 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KII94420.1 - 0.1 12.3 1.0 9 6.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 KII94420.1 - 0.13 11.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KII94420.1 - 0.14 12.2 1.5 19 5.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AIG1 PF04548.11 KII94420.1 - 0.19 10.8 0.1 13 4.8 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Herpes_BLLF1 PF05109.8 KII94420.1 - 0.86 7.4 9.7 1.4 6.8 6.7 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AAA_15 PF13175.1 KII94420.1 - 1.3 8.0 0.0 2.2 7.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ADH_zinc_N PF00107.21 KII94421.1 - 6.7e-21 74.1 0.6 1.1e-20 73.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII94421.1 - 6.2e-08 32.3 0.0 1.3e-05 24.8 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KII94421.1 - 0.084 13.7 0.1 0.22 12.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GPI-anchored PF10342.4 KII94422.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Collagen PF01391.13 KII94422.1 - 0.42 10.1 8.4 0.77 9.3 5.8 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Med9 PF07544.8 KII94423.1 - 0.00076 19.1 0.3 0.00099 18.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_3 PF13758.1 KII94423.1 - 0.029 14.1 0.1 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit Cupin_4 PF08007.7 KII94423.1 - 0.049 12.8 0.2 0.055 12.7 0.1 1.0 1 0 0 1 1 1 0 Cupin superfamily protein DEAD PF00270.24 KII94424.1 - 2e-37 128.2 0.1 3.3e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94424.1 - 2.6e-22 78.4 0.1 5.3e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KII94424.1 - 8.7e-05 21.4 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KII94424.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KII94424.1 - 0.097 12.4 0.7 0.33 10.7 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain HMG_box PF00505.14 KII94425.1 - 6.6e-18 64.7 1.0 8.3e-18 64.4 0.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII94425.1 - 6.5e-09 36.0 0.3 7.7e-09 35.7 0.2 1.1 1 0 0 1 1 1 1 HMG-box domain PolyA_pol PF01743.15 KII94426.1 - 2e-22 79.7 0.1 4e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KII94426.1 - 0.00021 20.7 0.3 0.00082 18.8 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF4287 PF14117.1 KII94426.1 - 0.0027 17.3 0.4 18 5.1 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4287) Glyco_hydro_16 PF00722.16 KII94428.1 - 6.5e-08 32.0 0.4 3e-07 29.9 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Arm PF00514.18 KII94429.1 - 9.2e-67 218.8 28.1 3.6e-13 48.7 0.1 11.7 10 2 2 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KII94429.1 - 8.2e-27 93.3 6.3 7.5e-07 29.3 0.0 7.2 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 KII94429.1 - 6.3e-19 66.3 17.1 0.013 15.5 0.0 10.5 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 KII94429.1 - 7.1e-17 61.3 9.0 0.031 14.7 0.1 8.4 6 2 3 9 9 9 5 HEAT-like repeat Arm_2 PF04826.8 KII94429.1 - 6.2e-12 45.1 9.8 0.0015 17.7 0.1 3.3 1 1 2 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 KII94429.1 - 9.8e-12 43.9 9.0 3.4e-08 32.2 0.1 2.9 2 1 0 3 3 3 2 Adaptin N terminal region KAP PF05804.7 KII94429.1 - 1.7e-10 39.4 2.4 2.6e-10 38.9 1.7 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KII94429.1 - 4.5e-08 32.5 7.5 0.0032 16.6 2.4 4.4 2 1 2 4 4 4 3 V-ATPase subunit H HEAT_PBS PF03130.11 KII94429.1 - 0.0079 16.5 9.0 46 4.8 0.1 7.1 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 KII94429.1 - 0.008 16.0 2.6 8.5 6.3 0.1 4.1 2 1 3 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KII94429.1 - 0.017 13.4 7.3 0.033 12.4 3.0 2.1 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.2 KII94429.1 - 0.019 15.3 0.0 6.9 7.1 0.0 3.5 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 KII94429.1 - 0.037 13.0 1.1 0.73 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) DUF3361 PF11841.3 KII94429.1 - 0.2 11.3 4.7 4.1 7.0 0.4 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3361) ADH_zinc_N PF00107.21 KII94432.1 - 1.5e-29 102.1 0.6 2.4e-29 101.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII94432.1 - 3.5e-19 69.9 0.1 8.9e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KII94432.1 - 3.3e-10 39.6 0.0 8.8e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KII94432.1 - 0.017 14.6 0.2 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KII94432.1 - 0.019 14.5 0.6 0.034 13.7 0.2 1.4 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ABC_membrane PF00664.18 KII94433.1 - 5.2e-47 160.5 27.7 3.2e-25 89.0 7.1 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KII94433.1 - 1.2e-43 148.7 0.1 7.8e-26 91.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII94433.1 - 2.9e-09 37.3 0.1 0.18 11.7 0.0 4.5 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KII94433.1 - 4.1e-09 35.9 5.1 0.063 12.4 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KII94433.1 - 7.8e-07 28.6 0.0 0.061 12.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KII94433.1 - 1.5e-05 25.0 0.9 0.12 12.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KII94433.1 - 0.00012 22.4 0.1 0.00012 22.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KII94433.1 - 0.00012 21.4 0.9 0.51 9.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KII94433.1 - 0.0015 19.0 0.1 3.2 8.2 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KII94433.1 - 0.0024 17.9 1.6 0.76 9.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KII94433.1 - 0.0024 17.3 0.1 0.54 9.7 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KII94433.1 - 0.0028 18.4 0.3 6.7 7.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 KII94433.1 - 0.0039 16.1 0.3 0.46 9.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KII94433.1 - 0.0045 16.5 0.1 2.2 7.6 0.1 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KII94433.1 - 0.0056 16.3 0.7 0.5 10.0 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KII94433.1 - 0.0072 16.2 0.2 1 9.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.10 KII94433.1 - 0.011 14.4 0.1 0.062 11.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_11 PF13086.1 KII94433.1 - 0.012 15.2 0.0 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KII94433.1 - 0.018 14.2 0.2 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 KII94433.1 - 0.018 14.8 1.4 0.099 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 KII94433.1 - 0.021 14.5 0.3 6.1 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KII94433.1 - 0.022 14.4 0.1 0.52 9.9 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 KII94433.1 - 0.037 14.2 0.4 0.49 10.6 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KII94433.1 - 0.047 14.0 0.4 14 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 KII94433.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KII94433.1 - 0.088 12.2 0.8 3.9 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 KII94433.1 - 1 9.1 6.6 2.3 8.0 0.0 2.7 3 0 0 3 3 2 0 Dynamin family MFS_1 PF07690.11 KII94434.1 - 9.2e-16 57.4 28.4 9.2e-16 57.4 19.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KII94434.1 - 1.3e-11 44.2 7.2 1.3e-11 44.2 5.0 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 GYF PF02213.11 KII94435.1 - 6.9e-16 57.5 0.1 6.9e-16 57.5 0.1 2.0 2 0 0 2 2 2 1 GYF domain DUF4339 PF14237.1 KII94435.1 - 0.44 10.1 2.9 0.51 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Acatn PF13000.2 KII94436.1 - 7.4e-137 457.1 27.2 9e-66 222.5 10.0 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.17 KII94437.1 - 6.1e-57 193.1 0.0 7.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KH_2 PF07650.12 KII94437.1 - 0.14 11.7 0.3 0.3 10.6 0.2 1.4 1 0 0 1 1 1 0 KH domain AAA PF00004.24 KII94438.1 - 2.8e-42 144.0 0.0 4.4e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KII94438.1 - 5.4e-27 93.4 0.1 2.6e-26 91.3 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KII94438.1 - 6.7e-22 77.1 6.9 6.7e-22 77.1 4.8 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 KII94438.1 - 1.5e-06 28.3 0.2 0.00033 20.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KII94438.1 - 7.1e-06 25.2 0.0 1.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KII94438.1 - 1.1e-05 25.2 0.0 3.6e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KII94438.1 - 1.2e-05 25.2 0.1 2.9e-05 23.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KII94438.1 - 1.7e-05 25.6 0.0 7.4e-05 23.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KII94438.1 - 1.7e-05 24.2 0.0 4.3e-05 23.0 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KII94438.1 - 5.5e-05 23.2 0.1 0.0035 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KII94438.1 - 0.00049 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KII94438.1 - 0.00057 19.3 0.3 0.18 11.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KII94438.1 - 0.0007 18.5 0.0 0.0027 16.6 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 KII94438.1 - 0.00075 19.4 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KII94438.1 - 0.00089 18.0 0.1 0.0021 16.8 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 KII94438.1 - 0.0018 18.5 0.2 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KII94438.1 - 0.0028 17.2 0.2 0.0063 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII94438.1 - 0.0045 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 KII94438.1 - 0.012 14.7 0.0 0.03 13.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KII94438.1 - 0.013 14.6 0.1 2.5 7.1 0.0 2.3 1 1 1 2 2 2 0 KaiC ResIII PF04851.10 KII94438.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 KII94438.1 - 0.018 15.1 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KII94438.1 - 0.02 14.0 0.1 0.2 10.7 0.1 2.3 1 1 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KII94438.1 - 0.022 14.4 0.0 0.34 10.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KII94438.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KII94438.1 - 0.057 13.1 2.6 0.37 10.4 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 KII94438.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 KII94438.1 - 0.065 12.9 0.0 0.065 12.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activat PF00158.21 KII94438.1 - 0.095 12.1 0.0 0.63 9.4 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KII94438.1 - 0.15 11.7 0.1 4.5 6.9 0.0 2.2 1 1 0 2 2 2 0 NTPase Viral_helicase1 PF01443.13 KII94438.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KII94438.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF4407 PF14362.1 KII94438.1 - 0.21 10.5 0.6 0.33 9.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_21 PF13304.1 KII94438.1 - 1.2 9.0 3.8 3.2 7.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain TIP120 PF08623.5 KII94441.1 - 2.5e-52 176.8 0.3 3.4e-51 173.1 0.0 3.0 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KII94441.1 - 3.8e-20 71.9 15.4 0.00012 22.2 0.1 8.5 6 1 2 8 8 7 6 HEAT repeats HEAT_EZ PF13513.1 KII94441.1 - 2.1e-15 56.6 34.1 0.0086 16.5 0.7 12.9 12 1 2 14 14 13 5 HEAT-like repeat HEAT PF02985.17 KII94441.1 - 1.2e-13 49.8 25.5 0.0022 17.9 0.0 13.0 14 0 0 14 14 13 2 HEAT repeat Cnd1 PF12717.2 KII94441.1 - 9.2e-10 38.6 0.7 0.27 11.0 0.0 6.8 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KII94441.1 - 7.3e-09 35.3 3.7 0.017 14.4 0.0 6.2 5 1 0 6 6 6 2 CLASP N terminal Adaptin_N PF01602.15 KII94441.1 - 1.3e-08 33.6 6.3 0.57 8.4 0.1 6.2 4 2 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KII94441.1 - 3.2e-06 27.4 0.0 5.3 7.5 0.0 6.5 7 0 0 7 7 6 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 KII94441.1 - 4.2e-05 23.4 6.1 21 5.1 0.0 7.3 7 0 0 7 7 7 0 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.4 KII94441.1 - 0.0017 18.3 1.5 7.7 6.3 0.0 4.9 6 0 0 6 6 6 0 Parkin co-regulated protein UME PF08064.8 KII94441.1 - 0.0041 17.0 0.1 5.2 7.0 0.0 4.3 4 0 0 4 4 3 1 UME (NUC010) domain DUF3385 PF11865.3 KII94441.1 - 0.0074 16.2 0.2 0.51 10.2 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) DUF1546 PF07571.8 KII94441.1 - 0.0092 16.0 0.3 10 6.2 0.0 5.0 5 0 0 5 5 4 0 Protein of unknown function (DUF1546) DUF2435 PF10363.4 KII94441.1 - 0.013 15.3 1.4 0.8 9.6 0.1 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) REF PF05755.7 KII94441.1 - 0.017 14.8 1.2 0.064 12.9 0.9 2.0 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) MMS19_C PF12460.3 KII94441.1 - 0.093 11.4 28.0 0.022 13.4 0.8 6.0 7 1 1 8 8 8 0 RNAPII transcription regulator C-terminal Arm PF00514.18 KII94441.1 - 0.25 11.2 6.9 32 4.5 0.0 5.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Mus7 PF09462.5 KII94441.1 - 0.28 9.9 1.4 2.7 6.6 0.0 2.7 3 0 0 3 3 3 0 Mus7/MMS22 family Nucleoplasmin PF03066.10 KII94441.1 - 0.43 10.0 6.3 0.86 9.1 4.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KII94441.1 - 2.3 6.0 6.8 2.4 5.9 2.9 2.0 2 0 0 2 2 2 0 Nop14-like family Asp PF00026.18 KII94442.1 - 4.9e-50 170.5 16.4 1.1e-49 169.4 11.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII94442.1 - 3.7e-07 30.2 5.9 3.1e-06 27.2 2.5 3.2 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII94442.1 - 3.8e-05 24.0 4.5 0.0011 19.4 0.7 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KII94442.1 - 0.14 11.6 2.9 0.79 9.2 0.3 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal DUF1764 PF08576.5 KII94443.1 - 0.58 10.9 11.3 15 6.4 0.1 4.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) UPF0370 PF13980.1 KII94443.1 - 0.86 9.4 5.6 2.2 8.1 3.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DAO PF01266.19 KII94444.1 - 5e-35 121.0 4.7 6.4e-35 120.7 3.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII94444.1 - 0.023 14.7 0.1 0.077 13.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KII94444.1 - 0.11 12.5 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribonuclease_3 PF00636.21 KII94446.1 - 0.00072 19.9 0.0 0.0039 17.6 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KII94446.1 - 0.0011 18.8 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like MutS_V PF00488.16 KII94447.1 - 4.8e-68 229.0 0.1 1.5e-67 227.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KII94447.1 - 3.9e-30 105.1 3.4 3.9e-30 105.1 2.3 1.8 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KII94447.1 - 3.2e-06 27.2 0.0 8.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KII94447.1 - 2.4e-05 24.4 0.0 7.6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain II YL1 PF05764.8 KII94448.1 - 6.8e-28 97.8 17.6 8.8e-28 97.5 12.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 KII94448.1 - 1.1e-12 47.2 0.1 1.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain L51_S25_CI-B8 PF05047.11 KII94449.1 - 6.4e-09 35.4 0.1 1.1e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ER-remodelling PF14755.1 KII94449.1 - 0.014 15.4 0.5 0.021 14.8 0.3 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller ArfGap PF01412.13 KII94451.1 - 7e-41 138.6 0.1 1e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_M1 PF01433.15 KII94452.1 - 3e-59 201.0 0.0 5.6e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KII94452.1 - 3.7e-31 107.6 0.0 8.5e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KII94452.1 - 2.7e-12 46.8 0.0 5.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KII94452.1 - 0.042 13.8 1.6 0.62 10.0 1.1 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase UPF0197 PF05251.7 KII94454.1 - 0.00028 21.1 7.0 0.00046 20.4 4.9 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) Virul_fac_BrkB PF03631.10 KII94454.1 - 0.018 14.3 5.4 0.019 14.3 3.8 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF3792 PF12670.2 KII94454.1 - 0.064 13.1 2.1 0.079 12.8 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) TB2_DP1_HVA22 PF03134.14 KII94455.1 - 3.2e-28 97.2 5.1 5e-28 96.6 3.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PgaD PF13994.1 KII94455.1 - 0.27 10.7 3.4 0.59 9.6 2.2 1.7 1 1 0 1 1 1 0 PgaD-like protein MFS_1 PF07690.11 KII94456.1 - 3.1e-15 55.7 30.3 3.1e-15 55.7 21.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KII94456.1 - 1.4e-08 34.3 9.1 1.4e-08 34.3 6.3 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Col_cuticle_N PF01484.12 KII94456.1 - 0.056 13.1 6.3 13 5.6 0.1 3.6 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.20 KII94457.1 - 1.7e-57 194.5 0.0 4.7e-57 193.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94457.1 - 1.5e-28 99.6 0.4 2.3e-20 72.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII94457.1 - 2e-05 23.7 0.2 0.00083 18.3 0.0 2.8 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KII94457.1 - 0.0043 16.8 0.6 0.02 14.6 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KII94457.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII94457.1 - 0.028 13.7 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Spindle_Spc25 PF08234.7 KII94458.1 - 5.1e-21 74.4 0.0 1.5e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF4200 PF13863.1 KII94458.1 - 0.0015 18.5 11.2 0.0015 18.5 7.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) CENP-F_N PF10481.4 KII94458.1 - 0.017 14.4 6.1 0.39 10.0 0.7 2.1 1 1 1 2 2 2 0 Cenp-F N-terminal domain CENP-F_leu_zip PF10473.4 KII94458.1 - 0.018 14.8 12.5 0.03 14.1 8.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KII94458.1 - 0.029 13.0 4.8 0.043 12.4 3.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 KII94458.1 - 0.12 10.7 6.6 0.16 10.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KII94458.1 - 0.26 10.3 10.4 0.34 9.9 7.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 KII94458.1 - 0.46 10.0 9.9 0.79 9.2 6.2 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 KII94458.1 - 0.47 10.0 12.5 0.65 9.6 8.0 1.6 1 1 1 2 2 2 0 Mnd1 family DUF1664 PF07889.7 KII94458.1 - 1.3 8.8 5.1 14 5.4 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 KII94458.1 - 2.2 7.8 9.9 3 7.4 6.8 1.3 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 KII94458.1 - 4.1 6.2 13.2 7.1 5.4 9.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 KII94458.1 - 4.7 5.5 5.7 6.5 5.0 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nup54 PF13874.1 KII94458.1 - 8.9 5.9 12.9 28 4.3 9.0 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Ribosomal_L4 PF00573.17 KII94459.1 - 0.0017 17.7 0.2 0.0026 17.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PGI PF00342.14 KII94461.1 - 1.1e-16 60.3 0.0 1.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF89 PF01937.14 KII94461.1 - 3.7e-10 39.1 0.0 4.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 U79_P34 PF03064.11 KII94467.1 - 0.43 10.0 5.4 0.5 9.8 3.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Retrotrans_gag PF03732.12 KII94468.1 - 0.034 14.2 0.7 0.07 13.1 0.3 1.8 1 1 1 2 2 2 0 Retrotransposon gag protein Sporozoite_P67 PF05642.6 KII94470.1 - 0.44 8.3 4.0 0.61 7.8 2.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3708 PF12501.3 KII94471.1 - 0.018 14.8 5.7 1.1 9.0 0.4 2.1 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter SLX9 PF15341.1 KII94471.1 - 0.1 13.0 0.2 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Filament PF00038.16 KII94471.1 - 0.49 9.8 6.2 0.76 9.1 1.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein HalX PF08663.5 KII94471.1 - 0.66 9.9 0.1 0.66 9.9 0.0 3.2 3 1 0 3 3 3 0 HalX domain Ubiquitin_2 PF14560.1 KII94473.1 - 0.011 15.9 1.1 1.9 8.8 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4235 PF14019.1 KII94473.1 - 0.094 12.5 0.3 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DDE_3 PF13358.1 KII94474.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Asp_protease_2 PF13650.1 KII94476.1 - 3.5e-06 27.4 0.0 8e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 KII94476.1 - 5.8e-05 23.0 0.0 8.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KII94476.1 - 0.028 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Peptidase_A2B PF12384.3 KII94476.1 - 0.097 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase COG5 PF10392.4 KII94479.1 - 0.11 12.4 0.9 0.18 11.7 0.6 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 HBS1_N PF08938.5 KII94482.1 - 3.9 7.6 8.2 7.7 6.7 5.7 1.4 1 0 0 1 1 1 0 HBS1 N-terminus Fusion_gly PF00523.13 KII94484.1 - 0.29 9.1 0.2 0.39 8.7 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 AAA_13 PF13166.1 KII94484.1 - 0.9 7.9 5.4 1.2 7.4 3.8 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KII94484.1 - 9.8 5.1 8.6 15 4.5 5.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Ribosomal_L1 PF00687.16 KII94485.1 - 1.7e-49 168.1 2.5 2.1e-49 167.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family 2OG-FeII_Oxy PF03171.15 KII94486.1 - 0.048 13.9 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-H2C2_2 PF13465.1 KII94487.1 - 1e-06 28.7 8.5 0.00018 21.6 2.6 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KII94487.1 - 9.8e-06 25.6 14.1 4e-05 23.7 0.9 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII94487.1 - 0.038 14.3 1.5 0.038 14.3 1.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Dof PF02701.10 KII94487.1 - 0.058 13.3 0.7 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger Caudal_act PF04731.7 KII94487.1 - 0.079 13.2 2.7 0.094 13.0 1.8 1.2 1 0 0 1 1 1 0 Caudal like protein activation region zf-C2H2_jaz PF12171.3 KII94487.1 - 0.15 12.2 2.0 0.43 10.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII94487.1 - 0.17 12.1 0.3 0.17 12.1 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.16 KII94487.1 - 0.87 9.5 5.4 17 5.3 3.7 2.1 1 1 0 1 1 1 0 IBR domain Metallophos PF00149.23 KII94489.1 - 2.1e-40 138.2 0.4 2.6e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KII94489.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.22 KII94490.1 - 1.5e-46 158.0 0.0 1e-21 77.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KII94490.1 - 1.6e-19 69.4 5.3 1.6e-19 69.4 3.7 1.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 KII94490.1 - 4e-18 66.3 1.4 0.00082 19.4 0.1 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KII94490.1 - 8e-10 38.1 0.2 0.00046 19.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KII94490.1 - 1.1e-09 37.8 2.7 0.17 11.1 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KII94490.1 - 3e-09 37.5 7.6 0.0027 18.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 KII94490.1 - 1e-07 32.1 0.2 0.00049 20.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 KII94490.1 - 2.1e-06 27.0 6.7 0.61 9.0 0.0 4.7 4 2 0 4 4 4 3 AAA ATPase domain Miro PF08477.8 KII94490.1 - 2e-05 25.0 0.0 0.17 12.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 KII94490.1 - 2.7e-05 23.8 0.1 0.26 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 KII94490.1 - 4.8e-05 22.6 0.0 0.011 14.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KII94490.1 - 5.2e-05 22.8 0.1 0.11 11.9 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KII94490.1 - 5.7e-05 22.7 0.2 1 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 KII94490.1 - 6.1e-05 23.1 0.0 0.18 11.9 0.0 3.5 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KII94490.1 - 0.00011 22.1 0.1 0.2 11.6 0.0 3.3 4 0 0 4 4 4 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KII94490.1 - 0.00013 22.7 0.3 0.62 10.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KII94490.1 - 0.00044 20.1 0.1 1.9 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KII94490.1 - 0.00047 19.6 0.3 4.1 6.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KII94490.1 - 0.00081 19.2 0.1 0.23 11.3 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KII94490.1 - 0.0023 18.2 0.9 8 6.7 0.0 3.8 4 1 0 4 4 4 0 AAA domain Dynamin_N PF00350.18 KII94490.1 - 0.0025 17.6 8.0 0.17 11.7 0.1 4.2 3 1 1 4 4 4 1 Dynamin family MobB PF03205.9 KII94490.1 - 0.0039 16.9 1.2 8.9 6.0 0.0 3.6 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KII94490.1 - 0.0044 16.9 0.0 11 5.9 0.0 4.2 4 1 0 4 4 4 0 AAA domain AAA_28 PF13521.1 KII94490.1 - 0.0054 16.6 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KII94490.1 - 0.008 16.3 3.1 6.7 6.9 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_5 PF07728.9 KII94490.1 - 0.0096 15.6 0.2 5.3 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 KII94490.1 - 0.015 15.0 6.5 0.7 9.6 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function DUF87 AAA PF00004.24 KII94490.1 - 0.022 14.9 0.2 22 5.2 0.0 4.0 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KII94490.1 - 0.023 14.1 0.1 6.1 6.2 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 KII94490.1 - 0.029 13.0 0.3 5.4 5.6 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit ArgK PF03308.11 KII94490.1 - 0.031 13.0 0.2 7.9 5.1 0.0 2.8 3 0 0 3 3 3 0 ArgK protein NTPase_1 PF03266.10 KII94490.1 - 0.16 11.6 2.3 5.3 6.7 0.1 3.2 4 0 0 4 4 3 0 NTPase AAA_30 PF13604.1 KII94490.1 - 0.39 10.2 6.0 0.92 9.0 0.3 3.3 4 1 0 4 4 3 0 AAA domain zf-MYND PF01753.13 KII94491.1 - 3.3e-12 46.0 26.6 2.5e-11 43.2 8.1 3.1 3 0 0 3 3 3 2 MYND finger F-box PF00646.28 KII94494.1 - 0.063 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 F-box domain Glyco_transf_52 PF07922.6 KII94494.1 - 0.098 11.6 0.3 0.21 10.5 0.1 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 52 Pkinase PF00069.20 KII94495.1 - 0.00046 19.4 0.0 0.00068 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KII94496.1 - 2e-05 23.8 0.1 4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94496.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4449 PF14613.1 KII94499.1 - 0.006 16.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Lyase_1 PF00206.15 KII94499.1 - 0.033 13.3 0.9 0.063 12.4 0.6 1.4 1 0 0 1 1 1 0 Lyase Pol_alpha_B_N PF08418.5 KII94501.1 - 0.13 11.8 11.7 0.077 12.5 1.3 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF2201_N PF13203.1 KII94503.1 - 2.4 7.2 9.5 3.8 6.5 6.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Pol_alpha_B_N PF08418.5 KII94506.1 - 3.5 7.0 10.3 8.8 5.7 2.1 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal ER-remodelling PF14755.1 KII94508.1 - 0.17 11.9 5.3 0.25 11.4 3.7 1.3 1 0 0 1 1 1 0 Intracellular membrane remodeller Pkinase PF00069.20 KII94510.1 - 6.4e-08 32.0 0.1 1.2e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KII94510.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KII94510.1 - 0.046 13.4 0.2 0.82 9.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family NPP PF08384.5 KII94513.1 - 0.014 15.0 0.5 0.014 15.0 0.4 2.0 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region Chordopox_RPO7 PF05864.7 KII94513.1 - 0.054 13.5 1.5 0.64 10.1 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TRI5 PF06330.6 KII94514.1 - 2e-15 56.3 0.0 2.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) KNOX2 PF03791.8 KII94514.1 - 0.11 11.7 0.8 0.72 9.1 0.1 2.3 2 0 0 2 2 2 0 KNOX2 domain TRI5 PF06330.6 KII94515.1 - 1.8e-18 66.3 0.0 2.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Pkinase PF00069.20 KII94516.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII94516.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII94516.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4661 PF15576.1 KII94516.1 - 0.41 10.2 4.5 0.7 9.4 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) N6-adenineMlase PF10237.4 KII94517.1 - 4.4e-33 114.2 0.0 5.2e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase F-box-like PF12937.2 KII94518.1 - 5.9e-06 25.9 0.2 1.8e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_2 PF00891.13 KII94520.1 - 2.2e-35 121.9 0.0 4.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII94520.1 - 5.2e-06 27.0 0.0 1.4e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII94520.1 - 0.00021 21.0 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII94520.1 - 0.0033 17.0 0.0 0.0067 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII94520.1 - 0.0062 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KII94521.1 - 1.8e-35 122.2 0.0 3.5e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII94521.1 - 0.00082 19.9 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII94521.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KII94521.1 - 0.021 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KII94521.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 KII94522.1 - 2.7e-21 75.1 1.8 5e-21 74.2 1.3 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 KII94522.1 - 0.0032 17.3 0.2 0.0054 16.6 0.2 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV F-box-like PF12937.2 KII94523.1 - 1.8e-06 27.5 0.6 8.6e-06 25.3 0.4 2.3 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 KII94524.1 - 5.8e-13 48.2 4.4 6e-11 41.8 0.2 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KII94524.1 - 1.5e-07 30.8 3.0 0.17 11.8 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KII94524.1 - 2.4e-06 26.9 0.0 1 9.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.26 KII94524.1 - 3.7e-05 23.4 0.1 0.00034 20.3 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain DnaJ PF00226.26 KII94524.1 - 0.0033 17.1 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain F-box-like PF12937.2 KII94525.1 - 8.3e-06 25.4 0.1 3.2e-05 23.5 0.1 2.1 1 0 0 1 1 1 1 F-box-like tRNA-synt_1g PF09334.6 KII94529.1 - 7.8e-102 340.8 0.0 4.7e-101 338.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KII94529.1 - 1e-17 63.4 0.7 3.5e-10 38.5 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KII94529.1 - 3.2e-09 36.3 0.0 0.00097 18.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KII94529.1 - 0.068 11.8 0.0 7.2 5.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) PBP PF01161.15 KII94530.1 - 1.4e-15 57.4 0.0 1.8e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Hydrolase_4 PF12146.3 KII94534.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Pkinase PF00069.20 KII94534.1 - 0.19 10.8 0.0 4.5 6.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Lipase_GDSL PF00657.17 KII94535.1 - 2e-07 31.0 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KII94535.1 - 1.2e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Mg_chelatase PF01078.16 KII94537.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KII94537.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_bind PF08675.6 KII94538.1 - 0.087 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain PLA2_B PF01735.13 KII94539.1 - 2.8e-102 342.4 0.0 3.6e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Coatomer_WDAD PF04053.9 KII94541.1 - 1.7e-152 508.3 0.0 3.2e-152 507.4 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KII94541.1 - 4e-52 172.3 5.3 5.1e-11 42.0 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KII94541.1 - 4e-05 23.3 0.9 2.4 7.9 0.0 4.6 4 1 0 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KII94541.1 - 0.88 7.6 4.7 2.5 6.1 0.1 3.5 3 2 1 4 4 4 0 Nucleoporin Nup120/160 AA_permease PF00324.16 KII94543.1 - 4.1e-122 407.9 44.8 4.7e-122 407.7 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII94543.1 - 2.7e-46 157.9 50.4 3.5e-46 157.6 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.6 KII94543.1 - 0.84 9.1 2.6 0.72 9.4 0.2 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) p450 PF00067.17 KII94544.1 - 3.8e-66 223.5 0.0 4.7e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PCNP PF15473.1 KII94546.1 - 0.017 15.4 0.4 0.019 15.2 0.3 1.2 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family RebB PF11747.3 KII94547.1 - 0.37 10.6 4.8 0.58 10.0 3.3 1.3 1 0 0 1 1 1 0 Killing trait Chitin_synth_2 PF03142.10 KII94548.1 - 2.8e-234 778.4 0.0 3.6e-234 778.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KII94548.1 - 4.1e-122 408.5 0.0 7.3e-122 407.7 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 KII94548.1 - 2.4e-17 63.5 0.0 2.8e-13 50.2 0.0 2.9 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KII94548.1 - 9.1e-17 60.6 0.0 1.4e-11 44.0 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KII94548.1 - 6.3e-15 55.3 1.0 6.3e-15 55.3 0.7 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KII94548.1 - 1.7e-13 50.1 0.9 6.5e-13 48.2 0.5 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 KII94548.1 - 4.4e-09 36.2 0.0 5.4e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KII94548.1 - 0.0013 18.0 0.0 0.0049 16.1 0.0 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 21 His_Phos_2 PF00328.17 KII94550.1 - 3.4e-55 187.7 0.0 4e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NUDIX PF00293.23 KII94552.1 - 9.8e-15 54.3 0.0 2.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Xan_ur_permease PF00860.15 KII94554.1 - 2.2e-63 214.0 31.7 1.3e-61 208.2 22.0 2.3 1 1 0 1 1 1 1 Permease family Phage_holin_5 PF06946.6 KII94554.1 - 2.4 8.4 5.3 0.5 10.5 0.1 2.6 3 0 0 3 3 3 0 Phage holin F-box PF00646.28 KII94555.1 - 0.0052 16.4 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII94555.1 - 0.013 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like RhgB_N PF09284.5 KII94556.1 - 1.3e-91 306.3 6.7 2.3e-91 305.5 4.6 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KII94556.1 - 3.6e-57 192.6 0.1 8.5e-57 191.4 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KII94556.1 - 2.2e-12 46.9 0.6 6.9e-12 45.3 0.4 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Hist_deacetyl PF00850.14 KII94557.1 - 1.6e-78 264.1 0.1 2.4e-78 263.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Utp14 PF04615.8 KII94557.1 - 0.036 12.2 2.2 0.048 11.8 1.5 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.5 KII94557.1 - 0.23 10.4 3.9 0.33 9.9 2.7 1.1 1 0 0 1 1 1 0 BUD22 DUF3245 PF11595.3 KII94557.1 - 0.68 10.2 6.1 1.2 9.3 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Pkinase_Tyr PF07714.12 KII94558.1 - 1.1e-32 113.1 0.0 1.2e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KII94558.1 - 6.8e-29 100.8 0.0 8.3e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KII94558.1 - 0.027 13.4 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Tim17 PF02466.14 KII94559.1 - 0.00072 19.5 0.2 9.3 6.3 0.0 4.1 4 0 0 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family DUF3493 PF11998.3 KII94559.1 - 0.0048 16.7 3.2 0.21 11.5 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3493) Ribosomal_L7Ae PF01248.21 KII94560.1 - 1.6e-27 94.8 2.3 2e-27 94.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2042 PF09743.4 KII94560.1 - 0.024 13.9 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) WD40 PF00400.27 KII94561.1 - 1.6e-35 119.6 21.6 5.6e-11 41.8 0.9 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KII94561.1 - 0.0012 18.6 0.0 0.23 11.1 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KII94561.1 - 0.0055 16.1 6.6 0.27 10.6 1.5 3.3 1 1 2 3 3 3 2 PQQ-like domain IKI3 PF04762.7 KII94561.1 - 0.006 14.4 0.4 0.027 12.2 0.0 2.1 3 0 0 3 3 3 1 IKI3 family DUF3312 PF11768.3 KII94561.1 - 0.038 12.2 0.1 0.066 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 KII94561.1 - 0.073 12.5 0.0 7.7 6.1 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 KII94561.1 - 0.51 10.6 5.6 1.4 9.2 0.1 4.1 4 1 0 4 4 4 0 PQQ-like domain WTF PF03303.8 KII94563.1 - 0.011 15.2 2.1 0.017 14.5 1.5 1.4 1 1 0 1 1 1 0 WTF protein PgaD PF13994.1 KII94563.1 - 0.043 13.2 0.2 0.043 13.2 0.1 1.7 2 0 0 2 2 2 0 PgaD-like protein Orai-1 PF07856.7 KII94563.1 - 0.093 12.2 1.5 0.18 11.3 1.0 1.6 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF3366 PF11846.3 KII94563.1 - 0.12 12.2 1.5 9.2 6.0 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) DUF1191 PF06697.7 KII94563.1 - 0.13 11.0 0.8 0.67 8.7 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1191) DUF975 PF06161.6 KII94563.1 - 0.13 11.9 4.1 0.2 11.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Oxidored_q2 PF00420.19 KII94563.1 - 0.22 11.1 8.3 2.6 7.6 0.3 2.4 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1049 PF06305.6 KII94563.1 - 0.64 9.5 6.7 2.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF2207 PF09972.4 KII94563.1 - 1.5 7.3 8.2 1.3 7.5 0.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Yip1 PF04893.12 KII94563.1 - 6.9 6.1 18.8 0.67 9.4 5.4 2.4 1 1 0 2 2 2 0 Yip1 domain WW PF00397.21 KII94564.1 - 0.11 12.4 2.2 0.22 11.4 0.3 2.3 2 0 0 2 2 2 0 WW domain Clathrin PF00637.15 KII94565.1 - 1e-26 93.2 0.1 2.3e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.4 KII94565.1 - 0.00087 19.2 0.3 0.01 15.8 0.1 2.7 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 KII94565.1 - 0.0058 16.4 2.5 0.026 14.3 1.7 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KII94565.1 - 0.04 13.6 0.9 0.19 11.4 0.6 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 KII94565.1 - 0.15 12.2 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Sigma70_ner PF04546.8 KII94565.1 - 0.84 9.2 13.0 1.6 8.2 9.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Trypan_PARP PF05887.6 KII94565.1 - 1.9 8.2 10.4 3.7 7.3 7.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 KII94565.1 - 5.4 5.3 15.4 7.8 4.8 10.7 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 KII94565.1 - 9.4 3.9 8.3 15 3.3 5.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BRCT PF00533.21 KII94568.1 - 1.3e-06 28.4 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KII94568.1 - 0.00077 19.2 0.0 0.0044 16.8 0.0 2.1 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 KII94568.1 - 0.0019 18.2 0.1 0.0055 16.8 0.1 1.7 1 1 0 1 1 1 1 Fibronectin type III domain Pkinase PF00069.20 KII94569.1 - 6.7e-62 208.9 0.0 8.5e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII94569.1 - 5.2e-31 107.6 0.0 1.4e-30 106.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII94569.1 - 0.00055 18.9 0.0 0.0009 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII94569.1 - 0.0017 18.1 0.4 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family 7tm_7 PF08395.7 KII94570.1 - 0.044 12.8 1.3 0.079 11.9 0.9 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor AF-4 PF05110.8 KII94570.1 - 0.73 7.6 11.6 1 7.1 8.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 KII94570.1 - 1.1 8.8 3.6 1.8 8.1 2.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Helicase_C PF00271.26 KII94571.1 - 4.7e-15 55.2 0.0 2.7e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII94571.1 - 0.047 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase BTB PF00651.26 KII94573.1 - 0.00032 20.6 0.3 0.001 19.0 0.2 1.9 1 1 0 1 1 1 1 BTB/POZ domain Myb_DNA-binding PF00249.26 KII94575.1 - 1.7e-08 34.3 0.7 3.8e-08 33.2 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII94575.1 - 7.8e-08 32.3 0.1 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2956 PF11169.3 KII94575.1 - 5.6 6.9 18.8 12 5.8 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DEAD PF00270.24 KII94577.1 - 8.4e-17 61.1 0.1 2e-16 59.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94577.1 - 1.8e-16 59.7 0.0 3.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII94577.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KII94577.1 - 0.0012 17.6 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Abhydrolase_6 PF12697.2 KII94579.1 - 2e-36 125.9 4.8 2.7e-36 125.5 3.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII94579.1 - 2e-21 76.6 0.0 3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII94579.1 - 2.7e-20 72.5 0.2 5.1e-20 71.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KII94579.1 - 3.3e-07 30.1 0.0 5.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 KII94579.1 - 2.1e-06 27.4 0.0 8.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KII94579.1 - 0.00076 18.7 0.1 0.33 10.1 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KII94579.1 - 0.00095 18.5 0.0 0.024 13.9 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF2048 PF09752.4 KII94579.1 - 0.0036 16.2 0.0 0.44 9.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 KII94579.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 KII94579.1 - 0.019 14.3 0.0 0.093 12.1 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 KII94579.1 - 0.026 13.7 0.8 0.055 12.7 0.4 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase BTB PF00651.26 KII94580.1 - 6e-06 26.2 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII94582.1 - 6.4e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII94583.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII94584.1 - 5.7e-06 26.2 0.1 8.7e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Tri3 PF07428.6 KII94585.1 - 2.4e-11 42.9 0.0 1.4e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Peptidase_M24 PF00557.19 KII94586.1 - 1e-44 152.6 0.0 1.2e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CbtB PF09489.5 KII94586.1 - 0.31 10.9 2.3 0.68 9.8 1.6 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) AA_permease PF00324.16 KII94587.1 - 5.8e-111 371.1 44.6 7.2e-111 370.8 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII94587.1 - 2.9e-33 115.0 52.8 3.5e-33 114.7 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease TAF4 PF05236.9 KII94588.1 - 1.1e-29 103.5 5.5 1.1e-28 100.2 3.8 2.1 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family zf-CCCH PF00642.19 KII94589.1 - 0.00023 20.7 1.5 0.00035 20.1 1.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII94589.1 - 0.5 10.4 4.9 0.96 9.5 3.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Vps36_ESCRT-II PF11605.3 KII94590.1 - 0.0026 17.5 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 KII94590.1 - 0.0035 17.5 0.0 0.0077 16.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial PH domain GRAM PF02893.15 KII94590.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DUF1469 PF07332.6 KII94591.1 - 0.038 13.7 6.8 0.15 11.7 4.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) EVE PF01878.13 KII94592.1 - 3.4e-45 153.5 0.2 5.5e-45 152.8 0.2 1.3 1 0 0 1 1 1 1 EVE domain Band_7 PF01145.20 KII94593.1 - 4.7e-23 82.0 5.1 8.1e-23 81.2 3.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TroA PF01297.12 KII94593.1 - 0.097 11.8 0.3 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Periplasmic solute binding protein family RGS PF00615.14 KII94594.1 - 0.00061 19.8 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2975 PF11188.3 KII94594.1 - 1.5 8.5 4.5 0.3 10.8 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) NYD-SP28_assoc PF14775.1 KII94595.1 - 0.026 14.2 2.8 1 9.1 0.2 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Bacillus_HBL PF05791.6 KII94595.1 - 0.043 13.1 5.9 0.028 13.7 0.6 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1192 PF06698.6 KII94595.1 - 0.17 11.7 8.8 1.3 8.9 3.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Atg14 PF10186.4 KII94595.1 - 2 7.2 27.3 19 4.1 0.5 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KII94595.1 - 2.3 6.5 10.9 1 7.6 5.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SpecificRecomb PF10136.4 KII94595.1 - 5 5.0 10.2 9 4.1 7.1 1.3 1 0 0 1 1 1 0 Site-specific recombinase RasGAP PF00616.14 KII94596.1 - 2e-33 115.7 0.0 3.5e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KII94596.1 - 8.7e-08 32.2 0.0 2.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 KII94596.1 - 2.4e-05 24.2 0.1 7.7e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal RRM_1 PF00076.17 KII94598.1 - 7.8e-32 108.7 0.0 4.7e-16 58.1 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94598.1 - 1.5e-18 66.5 0.0 1.8e-10 40.6 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94598.1 - 6.8e-12 45.0 0.0 4.6e-09 35.9 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII94598.1 - 6.7e-06 25.8 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KII94598.1 - 0.0013 18.4 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KII94598.1 - 0.16 11.7 0.0 0.77 9.5 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 RRP7 PF12923.2 KII94599.1 - 2.1e-33 115.1 2.1 2.1e-33 115.1 1.5 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KII94599.1 - 0.04 13.5 0.2 0.6 9.7 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleoplasmin PF03066.10 KII94599.1 - 3.9 6.9 10.1 8.3 5.9 7.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin TEX19 PF15553.1 KII94599.1 - 4 7.2 5.5 2.4 8.0 0.6 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF498 PF04430.9 KII94600.1 - 1.1e-29 102.1 0.0 1.5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.8 KII94602.1 - 0.0002 21.1 14.1 0.00037 20.3 4.7 2.4 2 0 0 2 2 2 2 CHCH domain YqzH PF14164.1 KII94602.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 YqzH-like protein LSM PF01423.17 KII94602.1 - 0.052 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 LSM domain Pet191_N PF10203.4 KII94602.1 - 0.91 9.6 11.6 0.41 10.7 4.9 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KII94602.1 - 1.7 8.7 12.9 0.43 10.6 4.4 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 KII94602.1 - 5.5 6.8 15.4 6.3 6.6 2.2 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like BPL_LplA_LipB PF03099.14 KII94603.1 - 1.3e-22 80.0 0.0 2.2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 KII94603.1 - 0.0038 16.8 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus PBP_like PF12727.2 KII94603.1 - 0.11 11.3 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 PBP superfamily domain TB2_DP1_HVA22 PF03134.14 KII94606.1 - 1.4e-13 50.4 0.2 6.2e-13 48.3 0.1 1.9 1 1 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.12 KII94607.1 - 3.6e-64 214.6 6.9 4e-64 214.5 4.8 1.0 1 0 0 1 1 1 1 G10 protein Na_H_Exchanger PF00999.16 KII94608.1 - 1.2e-60 205.0 51.9 2e-60 204.3 36.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2617 PF10936.3 KII94608.1 - 0.007 15.9 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF2617 DIOX_N PF14226.1 KII94609.1 - 5e-29 101.1 0.0 9.7e-29 100.2 0.0 1.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII94609.1 - 9e-20 70.8 0.0 1.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YdjO PF14169.1 KII94611.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Cold-inducible protein YdjO GDPD PF03009.12 KII94612.1 - 3.5e-32 111.9 0.0 4.6e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KII94612.1 - 0.0011 19.1 2.5 0.0014 18.7 0.3 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.16 KII94613.1 - 2.8e-32 110.9 0.0 3.9e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF359 PF04019.7 KII94613.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF359) DUF4167 PF13763.1 KII94614.1 - 0.056 13.4 1.1 0.075 13.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) DUF605 PF04652.11 KII94614.1 - 3.4 6.9 19.9 4.1 6.6 13.8 1.1 1 0 0 1 1 1 0 Vta1 like KAR9 PF08580.5 KII94614.1 - 8.9 4.4 14.1 10 4.2 9.8 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DASH_Spc19 PF08287.6 KII94616.1 - 1.1e-17 64.0 7.8 4.4e-16 58.8 5.4 2.1 1 1 0 1 1 1 1 Spc19 CASP_C PF08172.7 KII94616.1 - 0.029 13.3 1.4 0.044 12.8 1.0 1.2 1 0 0 1 1 1 0 CASP C terminal PspB PF06667.7 KII94616.1 - 0.26 11.2 2.6 2.1 8.3 0.4 2.3 2 0 0 2 2 2 0 Phage shock protein B FlxA PF14282.1 KII94616.1 - 2.7 8.0 5.4 26 4.8 0.1 2.4 2 1 0 2 2 2 0 FlxA-like protein Vps51 PF08700.6 KII94616.1 - 9.5 6.1 7.8 2.4 8.0 1.2 2.5 2 1 1 3 3 3 0 Vps51/Vps67 Prefoldin_2 PF01920.15 KII94616.1 - 9.8 5.9 9.3 4.4 7.1 0.6 2.3 2 0 0 2 2 2 0 Prefoldin subunit MoCF_biosynth PF00994.19 KII94617.1 - 1.5e-58 196.2 0.4 3.9e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KII94617.1 - 2.2e-30 105.1 0.0 3.3e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KII94617.1 - 1.6e-14 53.5 0.3 4.9e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Nup88 PF10168.4 KII94618.1 - 1.9e-23 82.2 0.0 4.1e-12 44.8 0.0 2.5 3 0 0 3 3 3 2 Nuclear pore component Nup54 PF13874.1 KII94618.1 - 0.21 11.2 10.5 2.3 7.8 3.3 2.9 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 WW PF00397.21 KII94619.1 - 0.059 13.2 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 WW domain PapC_C PF13953.1 KII94619.1 - 0.079 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PapC C-terminal domain Nsp1_C PF05064.8 KII94620.1 - 2.2e-32 111.1 0.0 4e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KII94620.1 - 2.2e-17 63.3 135.7 3.6e-06 27.1 32.8 4.6 1 1 3 4 4 4 4 Nucleoporin FG repeat region EzrA PF06160.7 KII94620.1 - 0.21 9.7 0.5 0.37 8.9 0.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 KII94620.1 - 1.6 9.0 3.9 62 3.9 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Kelch_4 PF13418.1 KII94622.1 - 4.4e-19 67.9 11.8 0.0013 18.4 0.1 7.2 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KII94622.1 - 1.1e-17 63.7 15.8 0.00085 19.4 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KII94622.1 - 1.9e-09 37.2 3.4 0.22 11.5 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KII94622.1 - 2.1e-06 27.1 1.6 0.016 14.7 0.1 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 KII94622.1 - 5.1e-05 23.2 7.2 5.1 7.4 0.1 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 KII94622.1 - 0.059 13.1 6.8 0.94 9.3 0.0 5.1 6 0 0 6 6 6 0 Kelch motif MARVEL PF01284.18 KII94622.1 - 2.2 8.0 12.9 0.2 11.4 3.4 2.8 2 1 1 3 3 3 0 Membrane-associating domain BUD22 PF09073.5 KII94623.1 - 0.018 14.1 13.6 0.029 13.4 9.4 1.2 1 0 0 1 1 1 0 BUD22 Borrelia_P83 PF05262.6 KII94623.1 - 1.5 6.9 5.2 2.3 6.4 3.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mitofilin PF09731.4 KII94624.1 - 2 6.9 9.9 2.9 6.4 6.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF966 PF06136.8 KII94624.1 - 2.7 7.3 23.6 3.7 6.8 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Toxin_12 PF07740.7 KII94625.1 - 0.0015 18.9 2.7 0.0033 17.8 2.0 1.6 1 1 0 1 1 1 1 Ion channel inhibitory toxin Toxin_7 PF05980.7 KII94625.1 - 0.23 11.4 5.6 0.4 10.7 3.9 1.4 1 0 0 1 1 1 0 Toxin 7 Fungal_trans PF04082.13 KII94627.1 - 9e-06 24.7 0.0 2.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII94627.1 - 7.8e-05 22.4 5.6 0.00015 21.6 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIX1 PF08167.7 KII94627.1 - 0.048 13.3 0.4 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Peptidase_S10 PF00450.17 KII94629.1 - 5.5e-98 328.8 0.0 6.7e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.11 KII94629.1 - 0.0021 16.3 0.0 0.0032 15.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E stn_TNFRSF12A PF12191.3 KII94629.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain GDPD PF03009.12 KII94631.1 - 1.1e-32 113.5 0.0 2.7e-32 112.2 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KII94631.1 - 2.5e-06 27.5 0.6 9.8e-06 25.6 0.2 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acetyltransf_1 PF00583.19 KII94632.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Mgm101p PF06420.7 KII94633.1 - 1.8e-90 300.8 0.0 2.3e-90 300.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Spc97_Spc98 PF04130.8 KII94634.1 - 2.3e-68 230.8 0.0 3.3e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GatB_N PF02934.10 KII94635.1 - 2.9e-108 361.1 0.0 3.7e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KII94635.1 - 6.7e-32 110.2 0.0 9.9e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 GatB domain Thioredoxin_4 PF13462.1 KII94636.1 - 4.3e-08 33.3 0.0 8.9e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin PCI PF01399.22 KII94637.1 - 3.7e-14 52.9 0.0 7.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain VWA PF00092.23 KII94638.1 - 0.00019 21.2 0.0 0.0015 18.3 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KII94638.1 - 0.0003 20.9 0.1 0.0035 17.4 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF2894 PF11445.3 KII94638.1 - 0.00041 20.6 0.0 0.0037 17.5 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2894) FAA_hydrolase PF01557.13 KII94639.1 - 2.1e-51 174.4 0.0 2.8e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Nop14 PF04147.7 KII94640.1 - 2.6e-247 822.9 1.0 3e-247 822.7 0.7 1.0 1 0 0 1 1 1 1 Nop14-like family HLH PF00010.21 KII94640.1 - 0.54 9.9 5.4 1.5 8.5 0.0 3.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain eIF-3_zeta PF05091.7 KII94641.1 - 1.1e-185 618.2 0.0 1.3e-185 617.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.17 KII94642.1 - 8.4e-18 63.7 0.0 1.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94642.1 - 3e-11 43.1 0.0 5.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94642.1 - 5.9e-08 32.4 0.0 9.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0560 PF10577.4 KII94642.1 - 0.27 9.4 9.5 0.42 8.8 6.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SOBP PF15279.1 KII94642.1 - 5.2 7.3 7.2 7.2 6.8 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AflR PF08493.5 KII94643.1 - 0.0026 16.8 3.3 0.0026 16.8 2.3 2.2 1 1 2 3 3 3 1 Aflatoxin regulatory protein DER1 PF04511.10 KII94644.1 - 7.7e-07 28.8 3.9 1.1e-06 28.3 2.7 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KII94644.1 - 2.8e-06 27.4 5.2 4.9e-06 26.6 3.6 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 KII94644.1 - 0.0022 18.2 0.1 0.0042 17.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) CUE PF02845.11 KII94644.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain ING PF12998.2 KII94649.1 - 1.8e-15 57.0 2.3 2.7e-15 56.5 1.6 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KII94649.1 - 8.4e-08 31.7 5.2 1.3e-07 31.1 3.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KII94649.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain GATA PF00320.22 KII94650.1 - 4e-09 35.6 4.3 7.4e-09 34.8 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 KII94650.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf TRP PF06011.7 KII94653.1 - 2.1e-45 155.1 18.4 2.1e-45 155.1 12.8 2.3 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KII94653.1 - 9.7e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 ML-like domain Pellino PF04710.9 KII94653.1 - 0.32 9.5 0.0 0.51 8.9 0.0 1.2 1 0 0 1 1 1 0 Pellino DUF3537 PF12056.3 KII94655.1 - 0.0018 17.0 0.2 0.0023 16.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3537) Beta_helix PF13229.1 KII94656.1 - 1.4e-06 28.1 41.1 4.5e-05 23.2 26.7 3.1 1 1 1 2 2 2 1 Right handed beta helix region PAP_central PF04928.12 KII94657.1 - 4.5e-105 350.0 0.0 7.3e-105 349.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KII94657.1 - 2.1e-42 144.3 0.0 3.4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KII94657.1 - 6.2e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 KII94657.1 - 0.021 12.3 0.0 0.039 11.5 0.0 1.3 1 0 0 1 1 1 0 Nrap protein Peptidase_S49 PF01343.13 KII94657.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 SPX PF03105.14 KII94657.1 - 0.054 13.2 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 SPX domain LRR_4 PF12799.2 KII94659.1 - 0.019 14.5 2.0 18 5.1 0.0 4.1 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 KII94659.1 - 1.3 9.5 5.4 13 6.4 0.1 4.0 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KII94659.1 - 4 8.0 5.7 19 6.0 0.0 4.6 5 0 0 5 5 5 0 Leucine rich repeat PAPS_reduct PF01507.14 KII94660.1 - 3.3e-39 134.4 0.0 4e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HlyD PF00529.15 KII94660.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Ribonucleas_3_3 PF14622.1 KII94661.1 - 5e-18 65.2 0.0 7.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KII94661.1 - 3.4e-13 50.0 0.0 7.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 KII94661.1 - 3.9e-06 27.3 0.0 6.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Coiled-coil_56 PF09813.4 KII94662.1 - 2.1e-06 27.6 0.0 3.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.10 KII94663.1 - 0.00055 19.5 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa YEATS PF03366.11 KII94665.1 - 2.1e-32 110.6 0.0 3.3e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 YEATS family UPF0240 PF06784.6 KII94665.1 - 0.013 15.1 0.7 0.021 14.5 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) PI3_PI4_kinase PF00454.22 KII94666.1 - 3.6e-48 164.0 0.0 7.9e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KII94666.1 - 1.7e-33 116.0 0.0 4e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KII94666.1 - 7.7e-21 74.0 0.0 5.7e-20 71.2 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 KII94666.1 - 4.8e-10 38.7 0.7 1.3e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.1 KII94666.1 - 0.028 14.7 0.2 0.24 11.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GHL1-3 PF11308.3 KII94666.1 - 0.082 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 Xpo1 PF08389.7 KII94666.1 - 0.43 10.4 7.8 0.28 11.0 0.3 4.2 4 1 1 5 5 5 0 Exportin 1-like protein TFIID-18kDa PF02269.11 KII94667.1 - 2.4e-32 110.5 0.1 5.1e-32 109.5 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Sec5 PF15469.1 KII94667.1 - 0.089 12.5 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 LptC PF06835.8 KII94667.1 - 0.18 11.1 1.0 0.31 10.4 0.5 1.5 1 1 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related Thaumatin PF00314.12 KII94670.1 - 4.9e-56 189.5 8.8 5.5e-56 189.3 6.1 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.16 KII94670.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Proteasome PF00227.21 KII94671.1 - 4.6e-45 153.2 0.0 5.2e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PCI_Csn8 PF10075.4 KII94672.1 - 3e-32 111.3 0.0 4.5e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KII94672.1 - 1.1e-31 109.9 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Proteasome PF00227.21 KII94673.1 - 6.9e-49 165.7 0.0 8.5e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII94673.1 - 4e-13 48.4 0.1 7.3e-13 47.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RecA PF00154.16 KII94673.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein GFO_IDH_MocA PF01408.17 KII94675.1 - 4.4e-18 65.9 0.2 7.2e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII94675.1 - 1.9e-06 27.6 0.0 3.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain MukB PF04310.7 KII94675.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal DUF1748 PF08520.5 KII94676.1 - 1.3e-25 88.8 0.0 1.4e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coat_F PF07875.7 KII94676.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Coat F domain RNR_inhib PF08591.5 KII94677.1 - 1.9e-05 25.5 0.1 2.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor zf-H2C2_2 PF13465.1 KII94678.1 - 1.1e-07 31.7 13.8 0.00028 21.0 1.9 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KII94678.1 - 5.9e-06 26.3 1.1 5.9e-06 26.3 0.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII94678.1 - 1.3e-05 25.1 15.8 0.0014 18.8 0.2 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KII94678.1 - 0.012 15.8 0.6 0.012 15.8 0.5 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KII94678.1 - 0.013 15.5 0.4 0.095 12.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KII94678.1 - 0.021 14.6 0.3 0.048 13.5 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-FCS PF06467.9 KII94678.1 - 0.1 12.2 1.2 0.67 9.6 0.4 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Aminotran_1_2 PF00155.16 KII94679.1 - 1.1e-58 198.8 0.0 1.3e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KII94679.1 - 7e-07 28.6 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KII94679.1 - 2.2e-05 22.9 0.0 3.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KII94679.1 - 4.5e-05 22.7 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KII94679.1 - 0.0026 16.5 0.0 0.045 12.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Gyro_capsid PF04162.7 KII94679.1 - 0.035 12.3 0.0 0.053 11.7 0.0 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) FAD_binding_8 PF08022.7 KII94680.1 - 7.6e-17 61.0 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KII94680.1 - 4.9e-15 55.7 0.0 7.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KII94680.1 - 1.2e-10 41.5 7.7 1.2e-10 41.5 5.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Ank_5 PF13857.1 KII94681.1 - 1.1e-08 35.0 0.0 2.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KII94681.1 - 5.6e-06 26.7 0.0 1.3e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KII94681.1 - 1.5e-05 25.1 0.0 2.8e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KII94681.1 - 2e-05 24.1 0.1 0.00016 21.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KII94681.1 - 0.00031 20.6 0.0 0.082 13.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat MFS_1 PF07690.11 KII94683.1 - 3.8e-45 154.1 40.6 3.8e-45 154.1 28.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KII94683.1 - 7.1e-08 31.4 23.2 1.3e-07 30.5 16.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KII94683.1 - 0.0038 15.4 4.6 0.0056 14.8 3.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.7 KII94683.1 - 0.011 14.1 0.0 0.018 13.4 0.0 1.4 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DEAD PF00270.24 KII94684.1 - 1.3e-46 158.1 0.0 6.1e-46 155.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94684.1 - 2e-23 82.0 0.0 4.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KII94684.1 - 0.0025 16.6 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KII94684.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PI31_Prot_N PF11566.3 KII94685.1 - 8.2e-25 87.2 0.0 1.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KII94685.1 - 6.1e-09 36.3 16.8 6.1e-09 36.3 11.6 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator DUF4611 PF15387.1 KII94686.1 - 1.6 8.8 7.3 0.99 9.5 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RhgB_N PF09284.5 KII94687.1 - 4.7e-87 291.4 4.7 7.7e-87 290.7 3.3 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KII94687.1 - 5.6e-58 195.2 0.1 1.1e-57 194.2 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KII94687.1 - 1.1e-11 44.6 2.2 1.3e-11 44.4 0.5 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II Ribosomal_L13 PF00572.13 KII94688.1 - 1.4e-45 154.4 0.1 1.7e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF605 PF04652.11 KII94689.1 - 7.5 5.8 10.2 83 2.4 7.1 2.1 1 1 0 1 1 1 0 Vta1 like Nup188 PF10487.4 KII94690.1 - 5.7e-19 67.6 0.0 1.8e-16 59.3 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF3414 PF11894.3 KII94690.1 - 4.8e-08 30.4 0.2 2e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3414) Pkinase PF00069.20 KII94691.1 - 1.3e-38 132.6 0.0 4.6e-23 81.6 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII94691.1 - 2.6e-11 43.0 0.0 3.4e-09 36.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KII94691.1 - 9.5e-05 22.2 1.0 0.0052 16.5 0.0 3.3 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KII94691.1 - 0.25 10.2 0.0 1.7 7.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DUF1992 PF09350.5 KII94693.1 - 3.8e-20 71.4 0.0 8.3e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) AAA_19 PF13245.1 KII94693.1 - 0.015 15.0 0.3 0.046 13.4 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain UCH PF00443.24 KII94694.1 - 2e-33 115.6 0.0 2.5e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII94694.1 - 6.5e-11 42.2 0.0 9.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_61 PF03443.9 KII94695.1 - 1.8e-63 214.2 0.1 2.2e-63 213.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pro_isomerase PF00160.16 KII94697.1 - 1.9e-36 125.6 0.0 3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KII94697.1 - 8.7e-16 57.3 0.0 2.6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94697.1 - 9.8e-12 44.6 0.1 2.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94697.1 - 2.9e-09 36.6 0.0 5.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 KII94698.1 - 8e-09 35.4 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Aldedh PF00171.17 KII94699.1 - 1.5e-108 363.1 0.0 1.8e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.16 KII94700.1 - 2.8e-61 206.8 0.0 3.1e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KII94701.1 - 9.5e-53 178.8 0.0 1.1e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Homeobox PF00046.24 KII94701.1 - 0.002 17.6 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Homeobox domain PAF-AH_p_II PF03403.8 KII94702.1 - 9e-53 178.9 0.0 1.1e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KII94702.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII94702.1 - 1.8e-13 50.8 1.6 3.1e-13 50.1 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII94702.1 - 5.3e-06 25.4 0.0 8.3e-05 21.5 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KII94702.1 - 0.00018 20.3 0.0 0.00094 18.0 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KII94702.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF936 PF06075.7 KII94703.1 - 0.014 14.3 9.9 0.018 13.9 6.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) YL1 PF05764.8 KII94703.1 - 3.6 7.1 12.9 6.9 6.2 9.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.27 KII94704.1 - 2.5e-42 141.2 9.9 3.5e-08 33.0 0.0 7.7 8 1 0 8 8 8 6 WD domain, G-beta repeat DUF3312 PF11768.3 KII94704.1 - 0.02 13.1 0.0 0.14 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 KII94704.1 - 0.026 13.9 0.2 6.1 6.2 0.1 2.9 2 1 0 2 2 2 0 PQQ-like domain Lactonase PF10282.4 KII94704.1 - 0.042 12.9 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 KII94704.1 - 0.39 11.0 5.7 12 6.3 0.0 4.0 4 1 0 4 4 4 0 PQQ-like domain peroxidase PF00141.18 KII94705.1 - 2.9e-28 98.9 0.0 4.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KII94705.1 - 6e-28 96.5 0.3 1.7e-27 95.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Arb1 PF09692.5 KII94706.1 - 0.011 14.5 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Fungal_trans PF04082.13 KII94707.1 - 5.6e-23 81.1 0.3 1.3e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII94707.1 - 0.001 18.8 8.6 0.001 18.8 6.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KII94708.1 - 3.6e-78 263.1 26.1 4e-78 262.9 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII94708.1 - 1.2e-27 96.5 29.9 1.2e-27 96.5 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KII94708.1 - 1.6e-08 33.2 4.3 3.2e-08 32.2 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ubiquitin PF00240.18 KII94709.1 - 1.9e-23 81.6 0.1 2.1e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KII94709.1 - 2.2e-14 52.8 0.3 2.4e-14 52.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KII94709.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain 2OG-FeII_Oxy_2 PF13532.1 KII94710.1 - 8.4e-15 55.1 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KII94710.1 - 5.8e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.17 KII94711.1 - 2.7e-07 30.6 0.6 6.6e-07 29.3 0.4 1.7 1 1 0 1 1 1 1 Thioesterase superfamily Transp_cyt_pur PF02133.10 KII94712.1 - 1.6e-30 106.0 36.9 6e-30 104.1 25.5 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 KII94713.1 - 1.7e-35 122.3 34.4 1.7e-35 122.3 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.17 KII94715.1 - 2.7e-07 30.6 0.1 4.1e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily adh_short PF00106.20 KII94716.1 - 6.3e-34 117.3 0.4 8.4e-34 116.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII94716.1 - 2.8e-30 105.8 0.0 3.5e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII94716.1 - 5.3e-19 68.5 0.1 7.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII94716.1 - 8.9e-06 25.2 0.1 2.3e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KII94716.1 - 0.019 14.5 0.2 0.82 9.2 0.1 2.8 1 1 0 2 2 2 0 Zinc-binding dehydrogenase SH3_9 PF14604.1 KII94717.1 - 1.3e-15 56.6 0.1 3.1e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KII94717.1 - 2.3e-15 56.6 0.1 5.3e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KII94717.1 - 3.9e-14 52.2 0.0 7.6e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KII94717.1 - 4.8e-13 49.0 0.2 1.2e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 KII94717.1 - 5.9e-13 47.9 0.1 1.3e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII94717.1 - 6.2e-09 35.2 0.0 1.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 KII94717.1 - 0.00041 20.5 0.5 0.0012 19.1 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain CH PF00307.26 KII94717.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Ste50p-SAM PF09235.5 KII94717.1 - 0.08 12.9 0.3 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ham1p_like PF01725.11 KII94718.1 - 7.6e-53 178.6 0.0 8.6e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family TPR_11 PF13414.1 KII94719.1 - 4.9e-15 54.9 0.8 2.6e-07 30.1 0.0 5.5 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 KII94719.1 - 5.1e-10 39.1 2.5 0.0053 16.6 0.0 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII94719.1 - 1.2e-09 37.3 0.1 0.019 14.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII94719.1 - 2.5e-08 33.1 9.1 0.0017 18.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII94719.1 - 4.1e-08 33.6 0.0 6.2e-06 26.7 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII94719.1 - 2.1e-06 27.8 10.6 0.015 15.8 0.0 6.0 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KII94719.1 - 2.7e-06 27.1 0.0 0.29 11.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KII94719.1 - 8.9e-06 25.1 3.5 1.2 9.0 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KII94719.1 - 0.00089 18.8 0.0 5.6 6.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII94719.1 - 0.0024 17.6 0.0 0.033 14.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Acetate_kinase PF00871.12 KII94719.1 - 0.15 10.6 0.0 1.6 7.1 0.0 2.0 2 0 0 2 2 2 0 Acetokinase family TPR_10 PF13374.1 KII94719.1 - 0.19 11.7 10.7 0.62 10.0 0.0 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat Rab5ip PF07019.7 KII94721.1 - 2.2e-14 53.3 3.4 3e-14 52.8 2.4 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3816 PF12822.2 KII94721.1 - 0.018 14.9 0.3 0.023 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Semialdhyde_dhC PF02774.13 KII94722.1 - 7.5e-37 126.9 0.0 1.2e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KII94722.1 - 3.9e-28 98.1 0.0 7.3e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KII94722.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TBCC PF07986.7 KII94722.1 - 0.15 11.4 0.4 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Tubulin binding cofactor C F-box-like PF12937.2 KII94724.1 - 4.6e-06 26.2 3.2 7.9e-06 25.5 2.2 1.4 1 1 0 1 1 1 1 F-box-like DUF1768 PF08719.6 KII94725.1 - 5.4e-20 71.7 0.0 7.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_3 PF08777.6 KII94726.1 - 3.5e-06 26.8 0.0 7.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 KII94726.1 - 0.053 13.5 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 KII94726.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 La domain SAP18 PF06487.7 KII94727.1 - 2.7e-25 88.4 0.0 3.4e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_transf_52 PF07922.6 KII94727.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 52 F-box-like PF12937.2 KII94728.1 - 8.4e-05 22.2 1.4 0.00027 20.5 1.0 2.0 1 0 0 1 1 1 1 F-box-like Cu_amine_oxid PF01179.15 KII94729.1 - 3.1e-97 325.9 0.0 5.7e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KII94729.1 - 8.1e-09 35.2 0.0 1.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 KII94729.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain DUF4432 PF14486.1 KII94729.1 - 0.14 10.7 0.1 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) ATG22 PF11700.3 KII94730.1 - 2e-101 339.8 20.2 2.2e-101 339.7 14.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KII94730.1 - 3e-14 52.5 27.1 9.1e-10 37.7 5.2 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily TFIIF_alpha PF05793.7 KII94731.1 - 0.45 8.8 4.1 0.66 8.2 2.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribonuclease_3 PF00636.21 KII94732.1 - 3.5e-44 149.8 0.0 2.3e-21 76.3 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KII94732.1 - 3.2e-25 88.5 0.4 1.1e-12 47.9 0.1 4.3 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KII94732.1 - 4.1e-10 39.3 0.0 9.4e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 KII94732.1 - 2.2e-05 24.2 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.17 KII94732.1 - 0.00069 18.9 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.11 KII94733.1 - 5.4e-10 38.9 0.2 6.5e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.17 KII94734.1 - 4.1e-176 585.8 0.2 4.6e-176 585.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.13 KII94735.1 - 4.1e-06 26.6 8.1 6.3e-06 26.0 5.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 KII94736.1 - 1.8e-60 203.4 0.0 2.6e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII94736.1 - 3.2e-09 35.9 0.2 8.5e-09 34.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.16 KII94737.1 - 3.4e-34 117.2 0.0 4.4e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KII94737.1 - 1.2e-14 54.0 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KII94737.1 - 1.3e-10 40.7 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssu72 PF04722.8 KII94738.1 - 1.5e-81 272.4 0.0 1.9e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein TFIIA PF03153.8 KII94738.1 - 1.4 8.7 5.5 1.9 8.3 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.2 KII94739.1 - 3e-08 33.2 0.4 1.4e-07 31.1 0.3 2.3 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 KII94739.1 - 0.071 13.3 2.9 6.5 7.4 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 KII94739.1 - 0.29 10.8 4.3 0.33 10.6 0.5 2.8 2 1 0 2 2 2 0 F-box domain Syntaxin-18_N PF10496.4 KII94740.1 - 3.5e-14 52.4 0.2 1.4e-13 50.5 0.1 2.0 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE_assoc PF09335.6 KII94741.1 - 2e-12 47.3 5.7 2e-12 47.3 3.9 2.5 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF996 PF06195.8 KII94741.1 - 4.2 7.3 10.3 4.7 7.1 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) 2OG-FeII_Oxy PF03171.15 KII94742.1 - 0.024 14.9 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KII94742.1 - 0.072 13.6 0.1 0.4 11.2 0.0 2.4 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily Cys_Met_Meta_PP PF01053.15 KII94743.1 - 1.3e-56 191.6 0.0 2.6e-56 190.5 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.17 KII94744.1 - 6.8e-19 67.2 0.0 6.4e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94744.1 - 6.2e-18 64.5 0.0 9e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94744.1 - 4.8e-17 61.5 0.0 1.7e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KII94744.1 - 0.001 18.8 0.0 0.012 15.4 0.0 2.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif 2OG-FeII_Oxy PF03171.15 KII94746.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KII94746.1 - 0.017 15.6 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TFIIB PF00382.14 KII94747.1 - 5.4e-36 122.2 1.1 2.4e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KII94747.1 - 2.8e-10 40.2 8.2 3e-08 33.7 0.3 2.5 2 0 0 2 2 2 2 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KII94747.1 - 1.5e-07 30.9 0.4 0.018 14.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain BLVR PF06375.6 KII94747.1 - 0.018 14.8 1.9 0.032 14.0 1.3 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Sld5 PF05916.6 KII94749.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 GINS complex protein Fungal_trans PF04082.13 KII94752.1 - 2.5e-19 69.1 0.1 6.6e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII94752.1 - 1.6e-05 24.7 11.9 1.6e-05 24.7 8.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_3 PF13640.1 KII94753.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KII94753.1 - 0.16 12.2 0.0 0.57 10.5 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 KII94754.1 - 8.5e-16 57.6 0.0 1.5e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 KII94754.1 - 0.0013 18.5 3.6 0.0031 17.3 2.5 1.6 1 0 0 1 1 1 1 IBR domain UBA PF00627.26 KII94754.1 - 0.19 11.6 5.6 0.053 13.3 0.7 2.7 3 0 0 3 3 3 0 UBA/TS-N domain Mito_carr PF00153.22 KII94755.1 - 2.7e-52 174.4 4.7 1.7e-18 66.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 KII94756.1 - 6.9e-73 245.7 0.0 8.6e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KII94757.1 - 1.2e-75 254.7 0.0 1.5e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2435 PF10363.4 KII94758.1 - 8.9e-30 102.4 3.0 1.9e-28 98.2 0.0 4.2 4 1 2 6 6 6 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KII94758.1 - 6.5e-05 22.3 1.2 6.5e-05 22.3 0.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) TFIIF_alpha PF05793.7 KII94758.1 - 5.8 5.1 4.8 3 6.1 1.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sedlin_N PF04628.8 KII94759.1 - 3.9e-28 97.9 0.1 4.8e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Opy2 PF09463.5 KII94760.1 - 0.0089 16.0 19.0 0.016 15.3 13.2 1.4 1 0 0 1 1 1 1 Opy2 protein ABC_tran PF00005.22 KII94761.1 - 3.3e-15 56.6 0.0 2e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KII94761.1 - 2.6e-07 30.9 0.1 4.9e-05 23.4 0.1 2.2 1 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KII94761.1 - 1.1e-05 24.8 0.0 1.6e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KII94761.1 - 0.0002 20.8 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KII94761.1 - 0.0013 19.1 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KII94761.1 - 0.0024 17.0 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KII94761.1 - 0.0073 15.4 0.0 0.038 13.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KII94761.1 - 0.0087 16.8 0.2 0.018 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KII94761.1 - 0.0089 15.5 0.1 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KII94761.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 KII94761.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KII94761.1 - 0.018 14.9 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KII94761.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KII94761.1 - 0.032 13.8 0.1 0.089 12.4 0.1 1.6 2 0 0 2 2 2 0 NACHT domain Arf PF00025.16 KII94761.1 - 0.034 13.4 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 KII94761.1 - 0.035 14.5 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein SMC_N PF02463.14 KII94761.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KII94761.1 - 0.066 11.7 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 KII94761.1 - 0.069 13.3 0.5 0.33 11.1 0.3 2.0 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KII94761.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KII94761.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 KII94761.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 MutS domain V AAA_13 PF13166.1 KII94761.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KII94761.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_14 PF13173.1 KII94761.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-CCHC_5 PF14787.1 KII94762.1 - 0.017 14.6 0.7 0.017 14.6 0.5 3.9 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 KII94762.1 - 0.08 12.6 20.6 1.1 9.0 2.6 4.5 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.1 KII94762.1 - 2.9 7.6 30.6 0.2 11.3 0.6 4.8 3 1 2 5 5 5 0 Zinc knuckle Baculo_ME53 PF06061.6 KII94762.1 - 5.5 5.8 6.3 9.5 5.1 4.4 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 zf-CCHC PF00098.18 KII94762.1 - 9.3 6.3 33.6 0.15 12.0 1.6 4.8 5 0 0 5 5 5 0 Zinc knuckle UQ_con PF00179.21 KII94764.1 - 8.7e-16 57.6 0.1 1.2e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KII94764.1 - 0.03 14.2 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain His_Phos_2 PF00328.17 KII94765.1 - 3.5e-85 286.3 0.0 4.7e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KII94765.1 - 4.1e-07 29.6 0.0 7.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain E1-E2_ATPase PF00122.15 KII94766.1 - 7.6e-45 152.7 0.3 4e-44 150.3 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KII94766.1 - 2.7e-42 145.6 0.3 4.5e-42 144.9 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KII94766.1 - 1.5e-28 98.6 3.3 7.1e-12 45.3 0.3 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 KII94766.1 - 2.8e-19 70.0 0.0 5.5e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KII94766.1 - 0.0047 16.5 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Spc97_Spc98 PF04130.8 KII94767.1 - 3.5e-115 385.3 0.0 4.3e-115 385.0 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family AMP-binding PF00501.23 KII94769.1 - 1.6e-88 296.9 0.1 2e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII94769.1 - 1.1e-10 42.3 0.1 3.4e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.10 KII94770.1 - 2.6e-36 124.4 0.2 6.6e-36 123.1 0.1 1.7 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KII94770.1 - 9.7e-34 116.7 0.4 2e-33 115.7 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KII94770.1 - 6.4e-27 90.5 63.3 0.0059 16.1 0.4 13.8 13 0 0 13 13 13 13 IQ calmodulin-binding motif CH PF00307.26 KII94770.1 - 1.2e-08 34.9 0.0 3.7e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 KII94771.1 - 1.1e-37 129.6 21.5 1.7e-37 129.0 14.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KII94771.1 - 1.3 8.5 7.6 0.052 13.0 1.1 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 HSP90 PF00183.13 KII94772.1 - 1.5e-122 409.7 33.9 2e-121 405.9 4.1 2.8 3 0 0 3 3 3 2 Hsp90 protein FF PF01846.14 KII94772.1 - 1e-37 127.8 23.9 1.2e-11 44.3 0.1 7.1 7 0 0 7 7 7 5 FF domain WW PF00397.21 KII94772.1 - 7.3e-11 41.7 4.8 1.5e-06 27.9 0.2 2.9 2 0 0 2 2 2 2 WW domain HATPase_c_3 PF13589.1 KII94772.1 - 1.6e-09 37.5 0.0 1e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KII94772.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 7tm_1 PF00001.16 KII94773.1 - 0.0011 18.1 2.6 0.0011 18.1 1.8 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KII94773.1 - 0.0077 15.9 0.0 0.0077 15.9 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Git3 PF11710.3 KII94773.1 - 0.026 14.1 11.0 0.06 12.9 7.6 1.6 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 KII94773.1 - 0.067 12.0 6.4 0.1 11.4 4.5 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor MadM PF03818.8 KII94773.1 - 0.34 10.4 2.7 2.1 7.9 0.3 2.6 1 1 1 2 2 2 0 Malonate/sodium symporter MadM subunit Git3 PF11710.3 KII94774.1 - 3.6e-05 23.4 10.2 8.2e-05 22.2 7.1 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KII94774.1 - 0.0089 15.7 0.0 0.04 13.6 0.0 2.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Adipogenin PF15202.1 KII94774.1 - 0.059 13.2 1.2 0.29 11.0 0.8 2.2 1 0 0 1 1 1 0 Adipogenin Dicty_CAR PF05462.6 KII94774.1 - 0.088 11.6 8.7 0.14 11.0 6.0 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor TFIIE_beta PF02186.10 KII94775.1 - 0.00076 19.4 0.6 0.0013 18.6 0.1 1.6 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF1180 PF06679.7 KII94775.1 - 0.25 11.1 2.2 0.52 10.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RNase_PH PF01138.16 KII94776.1 - 2.4e-25 89.3 0.0 3.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KII94776.1 - 0.0049 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SMC_N PF02463.14 KII94777.1 - 1e-20 73.9 0.1 1.8e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KII94777.1 - 5.5e-10 39.9 22.4 5.5e-10 39.9 15.5 5.7 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KII94777.1 - 0.00032 20.7 8.1 0.00091 19.2 0.3 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KII94777.1 - 0.0041 16.6 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_pol_Rpb1_5 PF04998.12 KII94777.1 - 0.022 14.0 0.1 28 3.8 0.0 2.9 2 2 0 2 2 2 0 RNA polymerase Rpb1, domain 5 ABC_tran PF00005.22 KII94777.1 - 5.2 7.3 16.5 4.6 7.5 4.2 4.2 3 1 0 3 3 3 0 ABC transporter Calcipressin PF04847.7 KII94778.1 - 0.88 9.1 6.3 1.6 8.2 4.4 1.4 1 0 0 1 1 1 0 Calcipressin 7tm_7 PF08395.7 KII94779.1 - 0.056 12.4 1.9 0.065 12.2 1.3 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Auto_anti-p27 PF06677.7 KII94782.1 - 4e-10 39.2 8.7 0.00013 21.6 0.5 3.2 3 2 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.16 KII94782.1 - 0.67 9.8 3.8 3.9 7.4 0.6 2.5 2 1 0 2 2 2 0 IBR domain Glyco_hydro_47 PF01532.15 KII94783.1 - 1.8e-131 438.9 0.0 2.2e-131 438.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KII94783.1 - 1.5e-09 37.4 0.0 3.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Pribosyltran PF00156.22 KII94784.1 - 6.3e-15 54.9 0.1 8.4e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KII94784.1 - 0.063 12.4 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_S3Ae PF01015.13 KII94785.1 - 3.8e-86 287.4 4.1 4.5e-86 287.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 KII94785.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region mRNA_cap_C PF03919.10 KII94785.1 - 0.059 13.6 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Autophagy_act_C PF03987.10 KII94786.1 - 6e-11 42.3 0.6 1.5e-09 37.8 0.2 2.6 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Thiolase_N PF00108.18 KII94787.1 - 1e-89 300.0 1.3 1.3e-89 299.6 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KII94787.1 - 3.3e-38 129.8 0.9 3.3e-38 129.8 0.7 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KII94787.1 - 9e-05 22.0 2.9 0.0024 17.4 1.0 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KII94787.1 - 0.048 13.3 0.3 0.98 9.1 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.11 KII94788.1 - 6.6e-33 113.8 24.8 9.1e-33 113.4 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KII94788.1 - 0.11 12.8 0.6 1.9 8.9 0.0 2.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phage_holin_5 PF06946.6 KII94788.1 - 0.38 10.9 3.3 0.31 11.2 0.6 2.2 2 0 0 2 2 2 0 Phage holin MFS_1 PF07690.11 KII94789.1 - 4.3e-31 107.9 21.8 6e-31 107.4 15.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 KII94789.1 - 7.1 6.6 21.1 0.75 9.8 3.5 4.2 2 1 2 4 4 4 0 Short repeat of unknown function (DUF308) ACPS PF01648.15 KII94790.1 - 8.8e-20 70.6 0.0 1e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GCV_T PF01571.16 KII94791.1 - 1.2e-15 57.5 0.0 1.7e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KII94791.1 - 0.006 16.5 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pet191_N PF10203.4 KII94792.1 - 4.4e-24 84.3 4.7 5.1e-24 84.0 3.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HALZ PF02183.13 KII94792.1 - 0.43 10.3 2.2 0.43 10.3 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper CHCH PF06747.8 KII94792.1 - 1.3 9.0 5.0 12 5.9 0.9 2.4 2 0 0 2 2 2 0 CHCH domain Piwi PF02171.12 KII94793.1 - 3.5e-75 252.7 0.0 5.5e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KII94793.1 - 3.2e-11 42.3 0.0 8e-11 41.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KII94793.1 - 3.2e-07 29.7 0.0 5.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Gp5_C PF06715.7 KII94795.1 - 0.021 14.6 2.6 0.021 14.6 1.8 4.8 5 0 0 5 5 5 0 Gp5 C-terminal repeat (3 copies) DUF1640 PF07798.6 KII94796.1 - 1.1e-08 35.3 4.3 1.2e-08 35.2 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HAUS2 PF15003.1 KII94796.1 - 0.13 11.2 3.1 0.51 9.3 2.1 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF3485 PF11984.3 KII94796.1 - 0.18 10.8 1.2 0.98 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3485) DUF1843 PF08898.5 KII94796.1 - 0.37 10.8 2.8 1.5 8.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) DUF904 PF06005.7 KII94796.1 - 0.66 10.3 5.0 4.4 7.6 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) cEGF PF12662.2 KII94797.1 - 0.14 11.8 6.5 0.063 12.9 1.5 2.4 2 0 0 2 2 2 0 Complement Clr-like EGF-like Dynamin_N PF00350.18 KII94798.1 - 2.1e-17 63.4 6.2 2.2e-17 63.3 0.0 3.6 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KII94798.1 - 1.3e-05 25.1 0.0 0.0078 16.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Flagellar_rod PF05149.7 KII94798.1 - 0.00015 21.1 0.3 0.00015 21.1 0.2 2.7 2 0 0 2 2 2 1 Paraflagellar rod protein ABC_tran PF00005.22 KII94798.1 - 0.00058 20.1 0.9 0.0048 17.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.13 KII94798.1 - 0.0046 16.4 0.0 0.0046 16.4 0.0 3.0 4 0 0 4 4 4 1 FtsK/SpoIIIE family DUF258 PF03193.11 KII94798.1 - 0.0055 15.9 0.1 0.016 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KII94798.1 - 0.015 15.7 0.0 0.092 13.2 0.0 2.4 3 0 0 3 3 3 0 Miro-like protein AAA_16 PF13191.1 KII94798.1 - 0.018 15.0 0.4 0.12 12.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain TBPIP PF07106.8 KII94798.1 - 0.022 14.3 13.3 0.045 13.2 0.6 3.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_29 PF13555.1 KII94798.1 - 0.034 13.6 0.1 0.092 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KII94798.1 - 0.043 13.9 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 KII94798.1 - 0.18 10.4 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein B3 PF02362.16 KII94799.1 - 2.6 7.7 5.2 9.7 5.9 3.6 1.9 1 1 0 1 1 1 0 B3 DNA binding domain Zip PF02535.17 KII94799.1 - 3.3 6.6 5.3 4.6 6.1 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ATP_bind_1 PF03029.12 KII94800.1 - 2.5e-71 239.9 0.0 5e-71 239.0 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KII94800.1 - 7.1e-05 23.6 0.1 0.00016 22.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII94800.1 - 0.00012 22.0 0.0 0.00048 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KII94800.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KII94800.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.21 KII94800.1 - 0.0032 16.9 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KII94800.1 - 0.0037 17.4 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KII94800.1 - 0.005 16.7 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KII94800.1 - 0.0067 15.2 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein ArsA_ATPase PF02374.10 KII94800.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.18 KII94800.1 - 0.017 14.5 0.0 0.063 12.6 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 KII94800.1 - 0.018 14.7 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KII94800.1 - 0.019 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 KII94800.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KII94800.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 KII94800.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 KII94800.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 KII94800.1 - 0.036 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KII94800.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 KII94800.1 - 0.041 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KII94800.1 - 0.049 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KII94800.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 KII94800.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KII94800.1 - 0.083 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KII94800.1 - 0.084 13.1 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 KII94800.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.24 KII94800.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KII94800.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KII94800.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.5 KII94800.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 KII94800.1 - 0.12 11.7 0.0 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KII94800.1 - 0.14 12.1 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 KII94800.1 - 0.14 11.5 0.0 1.4 8.3 0.0 2.3 3 1 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 KII94800.1 - 0.17 11.0 0.0 0.62 9.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mago-bind PF09282.5 KII94801.1 - 1.3e-12 46.9 1.0 2.4e-12 46.1 0.7 1.4 1 0 0 1 1 1 1 Mago binding Ldl_recept_a PF00057.13 KII94802.1 - 9 6.2 9.7 2.1 8.3 3.7 2.3 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A WD40 PF00400.27 KII94803.1 - 6e-63 206.6 30.9 5.2e-10 38.8 0.1 11.2 12 0 0 12 12 12 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 KII94803.1 - 0.0002 21.1 0.0 0.027 14.2 0.0 3.6 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 KII94803.1 - 0.06 13.0 0.5 44 3.7 0.0 3.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DEAD PF00270.24 KII94804.1 - 3.5e-16 59.1 0.0 1.4e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94804.1 - 2e-08 33.9 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 KII94805.1 - 7.4e-12 44.7 0.0 5.8e-08 32.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94805.1 - 1.4e-08 34.6 0.0 4.7e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UPF0020 PF01170.13 KII94805.1 - 0.018 14.6 0.1 0.15 11.5 0.0 2.1 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 KII94805.1 - 0.069 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Complex1_LYR_2 PF13233.1 KII94806.1 - 1.6e-10 41.3 0.1 1.9e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KII94806.1 - 0.0089 15.8 1.1 0.014 15.2 0.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HMG_box PF00505.14 KII94807.1 - 4.1e-13 49.3 0.8 9.1e-13 48.2 0.6 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII94807.1 - 5.7e-05 23.3 0.6 0.00016 21.9 0.4 1.7 1 1 0 1 1 1 1 HMG-box domain DUF3394 PF11874.3 KII94807.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Sua5_yciO_yrdC PF01300.13 KII94808.1 - 7e-53 178.5 0.0 1.3e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KII94808.1 - 2.1e-25 89.2 0.0 3.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.24 KII94809.1 - 4.6e-42 143.3 0.0 1e-41 142.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94809.1 - 5.9e-25 86.9 0.0 1.5e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII94809.1 - 0.031 14.1 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mob1_phocein PF03637.12 KII94811.1 - 1.7e-74 249.2 0.0 2e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DJ-1_PfpI PF01965.19 KII94812.1 - 9.5e-25 86.7 0.1 1.6e-24 86.0 0.1 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KII94812.1 - 3.6e-10 39.2 0.2 6.1e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DJ-1_PfpI PF01965.19 KII94813.1 - 6.6e-24 84.0 0.4 1.1e-23 83.3 0.3 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KII94813.1 - 2.1e-12 46.3 0.1 4.4e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KII94813.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase TPR_3 PF07720.7 KII94813.1 - 0.21 11.4 1.1 2.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.19 KII94814.1 - 8e-24 83.7 0.4 1.2e-23 83.2 0.3 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KII94814.1 - 1.1e-11 44.0 0.2 2.3e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family TPR_3 PF07720.7 KII94814.1 - 0.026 14.3 1.1 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 KII94815.1 - 5.1e-19 67.6 0.2 9.8e-10 37.9 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94815.1 - 1.1e-12 47.6 0.6 1.5e-10 40.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94815.1 - 4.4e-10 39.3 0.0 0.00029 20.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.1 KII94815.1 - 0.14 12.5 3.9 0.31 11.3 2.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.11 KII94816.1 - 7.1e-36 123.6 25.4 1e-35 123.0 17.6 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KII94816.1 - 4.1e-09 35.8 0.1 4.1e-09 35.8 0.1 2.7 2 0 0 2 2 2 1 TRAM1-like protein DUF2140 PF09911.4 KII94816.1 - 0.081 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Snf7 PF03357.16 KII94817.1 - 2.9e-32 111.4 20.4 3.5e-32 111.1 14.1 1.2 1 0 0 1 1 1 1 Snf7 DUF3867 PF12983.2 KII94817.1 - 0.12 12.3 1.0 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Birna_RdRp PF04197.7 KII94817.1 - 0.34 8.9 8.1 0.37 8.7 5.6 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DrsE_2 PF13686.1 KII94817.1 - 1.3 8.8 6.0 2.8 7.7 4.1 1.7 1 1 0 1 1 1 0 DsrE/DsrF/DrsH-like family MCPVI PF02993.9 KII94817.1 - 1.5 8.8 8.6 0.13 12.4 0.5 2.2 1 1 1 2 2 2 0 Minor capsid protein VI Viral_P18 PF04521.8 KII94817.1 - 4.9 6.6 9.3 1.7 8.1 2.7 2.4 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein AAA_13 PF13166.1 KII94817.1 - 5.1 5.4 13.4 5.8 5.2 8.2 1.6 1 1 1 2 2 2 0 AAA domain PLRV_ORF5 PF01690.12 KII94817.1 - 5.5 6.0 7.8 6.2 5.8 5.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 KII94817.1 - 7.8 4.6 14.9 11 4.1 10.3 1.3 1 0 0 1 1 1 0 Transmembrane protein NIF PF03031.13 KII94818.1 - 2.8e-49 166.8 0.0 4.2e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FMN_dh PF01070.13 KII94819.1 - 4.4e-117 390.9 0.0 6.3e-117 390.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KII94819.1 - 1.6e-19 69.4 0.0 3.4e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KII94819.1 - 0.00019 20.4 0.2 0.0087 14.9 0.2 2.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KII94819.1 - 0.00028 19.9 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Peptidase_M19 PF01244.16 KII94819.1 - 0.0084 15.0 0.0 0.02 13.8 0.0 1.6 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) NMO PF03060.10 KII94819.1 - 0.0097 15.0 0.6 0.16 11.1 0.5 2.1 1 1 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KII94819.1 - 0.038 13.2 0.1 6.9 5.8 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein MFS_1 PF07690.11 KII94820.1 - 4.4e-35 121.0 31.6 4.4e-35 121.0 21.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_1 PF13172.1 KII94820.1 - 1.8 8.4 7.3 0.22 11.3 0.8 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix zf-RING_2 PF13639.1 KII94821.1 - 5e-09 35.8 3.8 2.8e-08 33.4 2.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KII94821.1 - 1.9e-06 27.8 0.2 3.2e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KII94821.1 - 2.6e-05 23.7 0.3 4.5e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII94821.1 - 0.00012 22.0 0.9 0.00012 22.0 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII94821.1 - 0.00034 20.1 0.9 0.0017 17.8 0.2 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KII94821.1 - 0.0026 17.4 3.2 0.017 14.7 2.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KII94821.1 - 0.0063 16.3 3.7 0.05 13.4 2.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KII94821.1 - 0.0073 16.0 1.0 0.018 14.7 0.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII94821.1 - 0.032 14.1 1.3 0.032 14.1 0.9 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING tRNA-synt_2c PF01411.14 KII94822.1 - 1.3e-05 23.7 0.0 1.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) MFS_1 PF07690.11 KII94823.1 - 1.9e-34 118.9 34.0 1.9e-34 118.9 23.6 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.16 KII94824.1 - 2.2e-06 28.0 0.0 1.2e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KII94824.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KII94824.1 - 0.00089 18.2 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ras PF00071.17 KII94825.1 - 6.7e-45 152.3 0.0 7.7e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII94825.1 - 5.5e-14 52.6 0.1 9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII94825.1 - 9.7e-07 28.1 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KII94825.1 - 1.9e-05 24.2 0.1 0.00011 21.7 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII94825.1 - 0.0004 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 KII94825.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Spo12 PF05032.7 KII94827.1 - 8.2e-10 38.1 0.2 8.2e-10 38.1 0.1 1.8 2 0 0 2 2 2 1 Spo12 family Polyketide_cyc PF03364.15 KII94828.1 - 2.9e-20 72.5 0.0 3.7e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Chitin_synth_1 PF01644.12 KII94830.1 - 3.1e-64 215.6 0.1 4.8e-64 215.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KII94830.1 - 1.7e-28 98.1 0.2 3.6e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KII94830.1 - 1.3e-21 76.6 0.0 6.1e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KII94830.1 - 1.1e-10 41.5 1.9 1.1e-10 41.5 1.3 2.5 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KII94830.1 - 4.5e-06 26.6 0.0 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF4107 PF13389.1 KII94830.1 - 0.12 12.0 0.8 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) zf-RING_2 PF13639.1 KII94831.1 - 2.2e-07 30.5 7.8 3.2e-06 26.8 5.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII94831.1 - 2e-06 27.6 3.9 1.6e-05 24.8 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KII94831.1 - 3e-06 27.2 0.7 5.1e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KII94831.1 - 8.8e-06 25.2 1.9 3.9e-05 23.2 1.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII94831.1 - 1.3e-05 24.7 5.0 0.0003 20.4 4.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KII94831.1 - 1.5e-05 24.5 1.9 0.00068 19.2 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KII94831.1 - 0.0064 16.0 0.9 0.048 13.2 0.2 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KII94831.1 - 0.0068 16.2 1.2 0.0068 16.2 0.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII94831.1 - 0.0091 15.6 1.8 0.0091 15.6 1.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KII94831.1 - 0.0092 15.4 2.2 0.036 13.5 1.5 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KII94831.1 - 0.013 15.2 1.2 0.031 14.1 0.3 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC5 PF06221.8 KII94831.1 - 0.027 14.2 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-RING_3 PF14369.1 KII94831.1 - 0.046 13.7 1.9 3.1 7.8 0.3 2.4 2 0 0 2 2 2 0 zinc-finger zf-RING_6 PF14835.1 KII94831.1 - 0.063 13.0 1.3 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein KfrA_N PF11740.3 KII94831.1 - 0.16 12.4 6.0 0.4 11.1 1.8 2.6 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term HSCB_C PF07743.8 KII94831.1 - 2.3 8.7 7.6 53 4.3 4.1 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Prok-RING_4 PF14447.1 KII94831.1 - 4 7.0 8.8 2.5 7.7 2.8 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CCHC PF00098.18 KII94832.1 - 2.5e-32 109.2 45.6 3.3e-07 29.9 2.0 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 KII94832.1 - 2.5e-08 33.4 33.4 0.0044 16.6 0.6 6.0 6 1 0 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 KII94832.1 - 0.00068 19.2 37.4 0.0035 16.9 1.7 5.5 4 2 1 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 KII94832.1 - 0.0046 16.6 32.3 1.3 8.8 0.3 6.1 3 1 2 5 5 5 4 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 KII94832.1 - 0.2 11.7 29.7 0.6 10.1 0.4 3.6 2 1 1 3 3 3 0 DnaJ central domain Mu-like_Com PF10122.4 KII94832.1 - 0.46 9.5 0.0 0.46 9.5 0.0 3.9 5 0 0 5 5 5 0 Mu-like prophage protein Com Sulf_transp PF04143.9 KII94832.1 - 1.5 8.9 4.2 0.46 10.5 0.4 2.0 2 0 0 2 2 2 0 Sulphur transport YhfH PF14149.1 KII94832.1 - 1.6 8.5 28.0 0.74 9.6 0.2 5.1 5 0 0 5 5 5 0 YhfH-like protein Aminotran_1_2 PF00155.16 KII94834.1 - 9.4e-15 54.4 0.0 9.5e-09 34.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II 14-3-3 PF00244.15 KII94836.1 - 1.3e-75 253.5 0.0 1.4e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KII94836.1 - 0.15 12.0 1.5 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DS PF01916.12 KII94837.1 - 1.7e-134 447.6 0.0 2e-134 447.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sec7 PF01369.15 KII94838.1 - 6.6e-64 215.0 0.7 1.2e-63 214.2 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KII94838.1 - 2.8e-55 186.3 4.4 2.8e-55 186.3 3.1 2.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KII94838.1 - 3.6e-31 106.5 5.9 1.5e-30 104.5 0.2 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DUF1539 PF07560.6 KII94838.1 - 0.0046 16.8 0.1 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) HEAT PF02985.17 KII94838.1 - 0.006 16.5 0.0 0.83 9.9 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat SH3_1 PF00018.23 KII94839.1 - 3.5e-41 138.3 6.5 1.2e-14 53.4 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KII94839.1 - 1.8e-38 129.8 8.7 5.1e-13 48.3 0.2 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KII94839.1 - 6e-29 99.3 0.0 1.7e-08 33.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SHD1 PF03983.7 KII94839.1 - 1e-28 98.7 0.0 3.8e-28 96.9 0.0 1.9 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SH3_3 PF08239.6 KII94839.1 - 6.5e-07 29.4 2.1 0.41 10.8 0.0 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain hSH3 PF14603.1 KII94839.1 - 0.0021 18.0 0.0 0.67 10.0 0.0 2.5 2 0 0 2 2 2 2 Helically-extended SH3 domain RNA_pol_Rpb5_C PF01191.14 KII94839.1 - 0.2 11.2 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain GTP_EFTU PF00009.22 KII94840.1 - 1.3e-46 158.4 0.0 1.7e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KII94840.1 - 2.9e-24 85.1 0.0 8.2e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KII94840.1 - 6.1e-10 39.0 0.1 1.5e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII94840.1 - 0.001 18.9 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KII94840.1 - 0.025 14.1 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF605 PF04652.11 KII94840.1 - 0.22 10.9 8.6 0.29 10.4 6.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF1987 PF09345.5 KII94841.1 - 0.14 11.9 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1987) zf-MYND PF01753.13 KII94842.1 - 0.0086 15.9 14.0 0.0086 15.9 9.7 1.8 2 0 0 2 2 2 1 MYND finger BRCT PF00533.21 KII94844.1 - 2.1e-06 27.7 0.0 5.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4618 PF15397.1 KII94846.1 - 0.041 13.2 0.1 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) EF1G PF00647.14 KII94847.1 - 0.021 14.5 1.4 0.73 9.5 0.0 2.7 2 1 1 3 3 3 0 Elongation factor 1 gamma, conserved domain DUF1390 PF07150.6 KII94847.1 - 1.3 8.3 4.9 0.85 8.9 1.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1390) Mur_ligase_M PF08245.7 KII94848.1 - 4.3e-06 26.8 0.3 0.00014 21.9 0.2 2.7 1 1 0 1 1 1 1 Mur ligase middle domain Slx4 PF09494.5 KII94849.1 - 6.1e-08 32.3 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease IBN_N PF03810.14 KII94850.1 - 3.8e-06 26.7 0.4 0.0019 18.0 0.0 3.7 5 0 0 5 5 5 2 Importin-beta N-terminal domain Xpo1 PF08389.7 KII94850.1 - 0.00029 20.7 0.0 0.0055 16.6 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 KII94850.1 - 0.00097 19.3 0.0 0.0063 16.7 0.0 2.5 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KII94850.1 - 0.58 10.7 9.9 1.5 9.4 0.3 5.2 5 1 1 6 6 6 0 HEAT-like repeat F-box-like PF12937.2 KII94851.1 - 6.8e-05 22.5 0.1 0.00019 21.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII94851.1 - 8.2e-05 22.1 0.2 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII94852.1 - 0.00095 18.8 0.7 0.0041 16.7 0.1 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KII94852.1 - 0.0066 16.0 3.4 0.013 15.0 0.0 2.9 3 0 0 3 3 3 1 F-box domain CDC45 PF02724.9 KII94852.1 - 1.6 6.7 14.8 2.1 6.2 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 KII94852.1 - 2 6.6 19.3 2.7 6.2 13.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.7 KII94852.1 - 2.9 6.9 20.8 4.5 6.3 14.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 KII94852.1 - 4.1 6.6 13.5 6 6.1 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 KII94852.1 - 9.3 6.1 23.3 12 5.6 16.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 F-box PF00646.28 KII94854.1 - 0.0036 16.9 0.0 0.0094 15.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII94854.1 - 0.0039 16.8 0.8 0.0061 16.2 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII94855.1 - 0.0019 17.8 0.2 0.0073 15.9 0.1 2.1 1 0 0 1 1 1 1 F-box domain RmuC PF02646.11 KII94855.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 RmuC family CobT PF06213.7 KII94855.1 - 4.4 6.3 17.6 6.3 5.8 12.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop25 PF09805.4 KII94855.1 - 7.8 6.5 12.2 12 5.9 8.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Peptidase_S28 PF05577.7 KII94856.1 - 4.6e-52 177.0 1.5 1.2e-51 175.7 1.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KII94856.1 - 0.00014 21.1 0.1 0.0003 20.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4427 PF14468.1 KII94856.1 - 0.12 12.0 0.3 0.26 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) ARPC4 PF05856.7 KII94858.1 - 0.12 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) ATP_synt_I PF03899.10 KII94860.1 - 0.078 13.1 10.5 0.4 10.8 2.4 2.7 2 1 0 2 2 2 0 ATP synthase I chain CM_2 PF01817.16 KII94861.1 - 0.0021 18.0 0.1 2.8 8.1 0.0 2.9 3 0 0 3 3 3 2 Chorismate mutase type II Acetyltransf_1 PF00583.19 KII94862.1 - 2.3e-13 49.9 0.0 6e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII94862.1 - 1.9e-07 31.1 0.0 1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII94862.1 - 1.6e-06 27.7 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KII94862.1 - 1.1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII94862.1 - 2.5e-05 24.4 0.0 9.4e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KII94862.1 - 0.0032 17.3 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KII94862.1 - 0.0035 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KII94862.1 - 0.0042 16.9 0.0 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII94862.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KII94862.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family DUF1212 PF06738.7 KII94863.1 - 7e-29 100.6 1.7 7e-29 100.6 1.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KII94863.1 - 2.9e-13 49.8 9.6 2.9e-13 49.8 6.7 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3815) tRNA-synt_2d PF01409.15 KII94864.1 - 5.9e-84 281.1 0.0 2.1e-54 184.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KII94864.1 - 0.00019 20.3 0.8 0.0045 15.8 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KII94864.1 - 0.0017 18.0 0.0 0.0052 16.3 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) MFS_1 PF07690.11 KII94865.1 - 1.2e-18 66.9 50.4 4.5e-09 35.4 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KII94865.1 - 0.00021 19.9 6.6 0.00021 19.9 4.6 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like DUF1146 PF06612.6 KII94865.1 - 0.069 13.0 2.5 0.83 9.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) DUF1228 PF06779.9 KII94865.1 - 0.59 10.1 9.4 0.17 11.9 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Btz PF09405.5 KII94868.1 - 2.4e-09 37.3 4.8 2.4e-09 37.3 3.3 2.5 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Abhydrolase_6 PF12697.2 KII94869.1 - 2.6e-35 122.3 0.0 3.6e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII94869.1 - 7.1e-22 78.0 0.0 2.7e-21 76.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII94869.1 - 1.3e-13 50.9 0.0 4.7e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KII94869.1 - 1.7e-05 23.4 0.0 2.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KII94869.1 - 0.00095 18.9 0.1 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S28 PF05577.7 KII94870.1 - 3.6e-53 180.7 1.4 2.9e-52 177.7 1.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KII94870.1 - 0.00056 19.1 0.9 0.0018 17.5 0.6 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF305 PF03713.8 KII94870.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Methyltransf_2 PF00891.13 KII94870.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase WD40 PF00400.27 KII94871.1 - 5.5e-18 64.0 12.8 0.0029 17.4 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KII94871.1 - 1.7e-05 24.6 0.0 0.28 10.8 0.0 3.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KII94871.1 - 0.0013 18.3 1.1 0.92 9.2 0.0 3.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KII94871.1 - 0.029 12.6 0.0 0.1 10.8 0.0 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain F-box-like PF12937.2 KII94873.1 - 0.00031 20.4 0.7 0.00091 18.9 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII94873.1 - 0.0027 17.3 0.6 0.026 14.1 0.4 2.7 2 1 1 3 3 3 1 F-box domain Pex2_Pex12 PF04757.9 KII94874.1 - 1.7e-33 115.9 7.8 2.3e-33 115.5 5.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 KII94874.1 - 5.9e-05 22.7 3.4 6.3e-05 22.6 0.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KII94874.1 - 0.00087 19.1 1.9 0.0035 17.1 1.5 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KII94874.1 - 0.0013 18.5 4.8 0.0047 16.7 1.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KII94874.1 - 0.0026 17.7 2.0 0.0026 17.7 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII94874.1 - 0.0036 16.9 2.6 0.012 15.1 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.4 KII94874.1 - 0.0046 17.0 0.2 0.0085 16.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-rbx1 PF12678.2 KII94874.1 - 0.011 15.7 3.4 0.13 12.3 2.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KII94874.1 - 0.03 14.0 0.6 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger FYVE PF01363.16 KII94874.1 - 0.72 9.7 3.4 0.66 9.9 0.6 2.0 2 0 0 2 2 2 0 FYVE zinc finger THOC7 PF05615.8 KII94875.1 - 2.6e-20 73.1 3.9 4.4e-20 72.3 2.7 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 Filament PF00038.16 KII94875.1 - 0.0054 16.2 7.1 0.0089 15.5 4.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF4515 PF14988.1 KII94875.1 - 0.16 11.6 9.2 0.25 10.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DivIC PF04977.10 KII94875.1 - 0.3 10.6 6.2 2.9 7.4 1.2 2.3 1 1 1 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 KII94875.1 - 0.55 9.8 6.6 1 8.9 4.5 1.3 1 0 0 1 1 1 0 Mnd1 family DUF1640 PF07798.6 KII94875.1 - 0.98 9.4 5.3 2.1 8.3 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4140 PF13600.1 KII94875.1 - 1.9 9.0 9.0 7.2 7.1 0.7 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 KII94875.1 - 2 8.3 10.8 8 6.3 3.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.7 KII94875.1 - 5.8 6.9 7.1 4.2 7.3 0.7 3.3 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Lactamase_B_2 PF12706.2 KII94876.1 - 6.3e-22 78.0 0.0 1e-21 77.3 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KII94876.1 - 6e-10 39.0 0.1 1.3e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 KII94876.1 - 0.0052 16.2 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease Glyco_hydro_3 PF00933.16 KII94877.1 - 2e-52 178.0 0.0 2.9e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII94877.1 - 7.1e-48 163.0 0.2 7.1e-48 163.0 0.1 2.5 3 1 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII94877.1 - 3.2e-23 81.4 0.1 6.6e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain LRR_4 PF12799.2 KII94878.1 - 3.4e-11 42.4 0.0 0.088 12.4 0.0 6.8 4 3 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KII94878.1 - 7e-10 37.5 7.0 7 7.1 0.0 7.5 6 2 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.1 KII94878.1 - 1.3e-07 30.9 12.9 6.4 7.1 0.0 8.4 9 1 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.1 KII94878.1 - 4.3e-06 26.3 5.6 0.19 11.5 0.0 5.2 5 2 0 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 KII94878.1 - 6e-06 25.6 10.9 13 6.5 0.0 7.5 7 0 0 7 7 7 2 Leucine rich repeat RhoGEF PF00621.15 KII94879.1 - 9.1e-20 71.2 0.0 2.9e-16 59.8 0.0 2.8 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.24 KII94879.1 - 0.033 14.3 0.0 0.095 12.9 0.0 1.8 1 0 0 1 1 1 0 PH domain RhoGEF PF00621.15 KII94880.1 - 2.6e-35 121.9 0.0 6.8e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain zf-C3HC4_3 PF13920.1 KII94881.1 - 7.5e-07 28.7 11.8 1.2e-06 28.0 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII94881.1 - 9.6e-05 22.0 11.6 0.00016 21.3 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII94881.1 - 0.00024 20.8 12.0 0.00039 20.1 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KII94881.1 - 0.0004 19.9 11.8 0.013 15.0 9.2 2.2 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 KII94881.1 - 0.00042 20.2 13.0 0.00066 19.6 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TMF_DNA_bd PF12329.3 KII94881.1 - 0.00049 19.8 3.8 0.00049 19.8 2.6 3.7 4 0 0 4 4 4 1 TATA element modulatory factor 1 DNA binding zf-C3HC4 PF00097.20 KII94881.1 - 0.00099 18.7 12.0 0.0016 18.0 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.4 KII94881.1 - 0.0011 17.9 8.5 0.0011 17.9 5.9 2.4 2 1 0 2 2 1 1 UV radiation resistance protein and autophagy-related subunit 14 MutS_III PF05192.13 KII94881.1 - 0.0022 17.8 0.5 0.0031 17.3 0.4 1.2 1 0 0 1 1 1 1 MutS domain III DUF4201 PF13870.1 KII94881.1 - 0.0079 15.6 6.7 0.0079 15.6 4.6 2.6 2 1 1 3 3 2 1 Domain of unknown function (DUF4201) Spt4 PF06093.8 KII94881.1 - 0.011 15.5 4.1 0.014 15.2 0.1 2.4 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger TerY-C PF15616.1 KII94881.1 - 0.02 14.7 3.7 0.04 13.8 2.6 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.1 KII94881.1 - 0.025 14.1 8.9 0.35 10.4 2.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FlaC_arch PF05377.6 KII94881.1 - 0.03 14.1 1.7 3.1 7.7 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AATF-Che1 PF13339.1 KII94881.1 - 0.032 14.3 13.1 0.66 10.1 3.1 2.8 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3080 PF11279.3 KII94881.1 - 0.067 12.3 0.3 0.13 11.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) zf-TFIIIC PF12660.2 KII94881.1 - 0.13 12.1 3.3 0.31 10.9 2.3 1.6 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex TSC22 PF01166.13 KII94881.1 - 0.58 10.1 6.5 23 5.0 0.0 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family zf-C2HC_2 PF13913.1 KII94881.1 - 0.59 9.8 7.4 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Hemerythrin PF01814.18 KII94881.1 - 0.92 9.6 9.9 0.48 10.5 1.6 2.9 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain zf-RING_UBOX PF13445.1 KII94881.1 - 0.98 9.1 9.2 2.5 7.8 6.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 KII94881.1 - 0.99 8.9 10.0 1.8 8.1 6.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3138 PF11336.3 KII94881.1 - 1.1 7.4 2.8 1.9 6.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DZR PF12773.2 KII94881.1 - 1.1 9.0 11.1 47 3.8 8.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon Herpes_UL32 PF06070.6 KII94881.1 - 2.3 6.5 16.5 0.1 11.0 3.7 2.1 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 zf-C3HC4_4 PF15227.1 KII94881.1 - 3.4 7.6 13.7 6.2 6.7 9.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Spc7 PF08317.6 KII94881.1 - 3.6 6.1 11.1 0.31 9.6 2.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.1 KII94881.1 - 5.8 6.0 17.6 0.078 12.1 6.7 2.0 2 1 0 2 2 1 0 Growth-arrest specific micro-tubule binding DUF2052 PF09747.4 KII94882.1 - 3.8e-11 43.2 9.2 5e-11 42.8 6.4 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) AflR PF08493.5 KII94883.1 - 2.7 6.9 4.9 3.1 6.7 3.4 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DNase_NucA_NucB PF14040.1 KII94884.1 - 2.7e-07 30.7 1.9 7.6e-07 29.2 0.4 2.3 1 1 1 2 2 2 1 Deoxyribonuclease NucA/NucB DNase_NucA_NucB PF14040.1 KII94885.1 - 4.3e-06 26.8 0.8 2.3e-05 24.4 0.6 2.1 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB Myb_DNA-bind_6 PF13921.1 KII94886.1 - 3.8e-17 62.1 6.0 1.1e-12 47.8 0.1 4.0 3 2 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KII94886.1 - 4.3e-17 61.9 7.1 1.8e-08 34.3 0.1 4.6 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KII94886.1 - 0.00049 20.1 1.4 0.00049 20.1 1.0 3.6 2 2 2 4 4 4 1 Myb/SANT-like DNA-binding domain MbeD_MobD PF04899.7 KII94886.1 - 0.019 14.8 0.1 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 MbeD/MobD like AAA PF00004.24 KII94889.1 - 5.8e-19 68.5 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII94889.1 - 0.016 15.3 0.5 1.3 9.1 0.2 2.9 2 1 0 2 2 2 0 AAA domain Myb_DNA-bind_6 PF13921.1 KII94890.1 - 1.7e-05 24.8 1.4 3.3e-05 23.9 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KII94890.1 - 0.0018 18.2 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C4H2 PF10146.4 KII94890.1 - 0.014 15.4 0.3 0.034 14.1 0.2 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein DUF202 PF02656.10 KII94891.1 - 2.5e-14 53.2 1.4 2.5e-14 53.2 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 KII94891.1 - 0.024 14.3 1.9 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) TctB PF07331.6 KII94891.1 - 0.048 13.3 3.6 0.11 12.1 0.4 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family 7tm_6 PF02949.15 KII94891.1 - 0.054 12.3 0.2 0.082 11.7 0.1 1.2 1 0 0 1 1 1 0 7tm Odorant receptor DUF2530 PF10745.4 KII94891.1 - 1.8 8.6 7.7 0.97 9.4 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) zf-U1 PF06220.7 KII94892.1 - 2.1e-20 71.9 5.8 2.9e-20 71.5 4.0 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KII94892.1 - 0.0019 18.2 2.7 0.0031 17.6 1.9 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding LSM PF01423.17 KII94893.1 - 3.3e-18 65.0 0.0 4.1e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4050 PF13259.1 KII94894.1 - 0.14 12.1 0.5 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) F-box-like PF12937.2 KII94895.1 - 6.2e-12 45.0 2.8 6.2e-12 45.0 1.9 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KII94895.1 - 1.2e-08 34.4 0.7 0.047 13.3 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KII94895.1 - 0.017 14.7 1.5 0.017 14.7 1.0 4.9 4 0 0 4 4 4 0 F-box domain Acetyltransf_1 PF00583.19 KII94896.1 - 1.7e-14 53.5 0.0 2.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KII94896.1 - 1.8e-05 24.8 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII94896.1 - 4e-05 23.2 0.0 5.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KII94896.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII94896.1 - 0.026 14.3 0.2 0.055 13.3 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KII94896.1 - 0.038 13.9 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KII94896.1 - 0.094 12.8 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF676 PF05057.9 KII94897.1 - 2.6e-07 30.1 0.0 5.9e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KII94897.1 - 1.6e-05 24.9 0.3 3.8e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII94897.1 - 2.6e-05 24.0 1.4 0.00012 21.8 1.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KII94897.1 - 0.0003 20.4 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 KII94897.1 - 0.0013 18.3 0.3 0.0028 17.2 0.2 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 KII94897.1 - 0.0029 16.9 0.1 0.018 14.3 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KII94897.1 - 0.0035 16.9 0.0 0.0083 15.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.2 KII94897.1 - 0.006 15.4 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2974 PF11187.3 KII94897.1 - 0.013 14.8 0.0 0.09 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) LCAT PF02450.10 KII94897.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 KII94897.1 - 0.15 11.1 0.0 11 5.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Aldolase_II PF00596.16 KII94899.1 - 3.9e-50 170.0 0.0 4.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain tRNA-synt_1c PF00749.16 KII94900.1 - 5e-103 344.0 0.0 6.4e-103 343.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KII94900.1 - 5.6e-33 114.0 0.0 1.1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 KII94900.1 - 2.8e-27 95.2 0.0 4.2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 KII94900.1 - 1.6e-08 35.1 3.5 1.6e-08 35.1 2.4 2.4 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CPSF100_C PF13299.1 KII94901.1 - 3.8e-29 101.9 1.2 4.7e-28 98.3 0.0 2.8 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KII94901.1 - 2.2e-22 79.3 0.0 8.6e-22 77.4 0.0 2.0 2 1 0 2 2 2 1 Beta-Casp domain DUF1772 PF08592.6 KII94902.1 - 3.7e-23 81.7 0.5 5e-23 81.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1422 PF07226.6 KII94902.1 - 0.041 13.6 0.3 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) PAF-AH_p_II PF03403.8 KII94903.1 - 8.5e-29 100.0 0.0 1.8e-28 98.9 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KII94903.1 - 3.4e-10 39.8 0.6 8e-10 38.6 0.3 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII94903.1 - 1.8e-05 24.7 6.5 5.3e-05 23.2 4.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII94903.1 - 0.00017 20.5 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 KII94903.1 - 0.019 13.7 0.0 0.28 9.9 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Hydrolase_4 PF12146.3 KII94903.1 - 0.093 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF2424 PF10340.4 KII94903.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Kelch_3 PF13415.1 KII94905.1 - 0.016 15.3 0.5 4.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF4448 PF14610.1 KII94906.1 - 0.00071 19.1 0.1 0.00089 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KII94906.1 - 0.0016 18.8 0.1 0.0038 17.6 0.1 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GFA PF04828.9 KII94907.1 - 1e-23 83.0 0.5 2e-23 82.1 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 KII94907.1 - 0.0058 16.3 0.0 0.0058 16.3 0.0 1.8 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 KII94907.1 - 0.13 12.1 2.9 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like BTB PF00651.26 KII94908.1 - 0.00036 20.4 0.0 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUF1510 PF07423.6 KII94909.1 - 1.3e-05 24.7 0.2 2.2e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) 7tm_1 PF00001.16 KII94909.1 - 0.25 10.4 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Peptidase_S49_N PF08496.5 KII94909.1 - 0.27 11.0 0.7 0.49 10.1 0.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 KII94909.1 - 0.77 7.7 10.0 1.1 7.2 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3987 PF13148.1 KII94909.1 - 7.1 5.0 14.0 11 4.5 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YqfQ PF14181.1 KII94909.1 - 9.8 6.1 7.1 20 5.1 4.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein DIOX_N PF14226.1 KII94910.1 - 5.4e-25 88.1 0.1 9.1e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII94910.1 - 2.3e-18 66.2 0.1 6e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Orthoreo_P10 PF07204.6 KII94911.1 - 0.016 14.9 0.1 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 RCC1 PF00415.13 KII94912.1 - 6.2e-59 196.0 16.2 8.5e-12 45.0 0.1 7.7 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KII94912.1 - 9.3e-35 117.5 44.3 1.3e-07 31.0 1.7 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.1 KII94912.1 - 0.66 9.6 2.9 2.8 7.6 0.1 2.8 3 0 0 3 3 3 0 PapC C-terminal domain Aldedh PF00171.17 KII94913.1 - 6.3e-151 502.8 0.1 7.7e-151 502.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KII94913.1 - 0.00012 20.9 0.0 0.00029 19.6 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Snf7 PF03357.16 KII94914.1 - 2e-43 147.7 13.0 2.3e-43 147.5 9.0 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 KII94914.1 - 0.0089 15.7 9.7 0.4 10.4 0.0 3.4 2 1 1 3 3 3 1 Prefoldin subunit NPV_P10 PF05531.7 KII94914.1 - 0.074 13.3 1.8 3.2 8.0 0.1 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 KII94914.1 - 0.19 11.6 2.6 7.3 6.5 0.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 KII94914.1 - 2.4 8.1 7.6 0.51 10.3 1.7 2.3 1 1 1 2 2 2 0 FlxA-like protein NuA4 PF09340.5 KII94914.1 - 2.9 7.6 4.9 0.45 10.1 0.2 2.1 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 fn1 PF00039.13 KII94916.1 - 0.13 12.1 0.1 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type I domain Abhydrolase_1 PF00561.15 KII94917.1 - 9e-20 71.2 0.1 9.2e-18 64.6 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KII94917.1 - 2.8e-12 47.0 2.8 3.2e-11 43.5 1.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KII94917.1 - 4e-05 23.1 0.1 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KII94917.1 - 0.003 17.3 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Pex14_N PF04695.8 KII94917.1 - 0.0059 16.6 1.4 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Snf7 PF03357.16 KII94919.1 - 1e-20 73.8 13.6 1.2e-20 73.5 9.4 1.1 1 0 0 1 1 1 1 Snf7 DDE_Tnp_Tn3 PF01526.12 KII94919.1 - 0.0089 14.6 0.4 0.011 14.4 0.3 1.3 1 0 0 1 1 1 1 Tn3 transposase DDE domain Ist1 PF03398.9 KII94919.1 - 0.028 13.8 3.2 0.049 13.0 2.2 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway T2SM PF04612.7 KII94919.1 - 0.94 9.2 7.6 0.18 11.5 0.3 2.4 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M SYCE1 PF15233.1 KII94919.1 - 1.4 8.8 7.3 3.6 7.5 4.4 2.2 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Fib_alpha PF08702.5 KII94919.1 - 7.6 6.6 10.6 4.2 7.4 0.7 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Erv26 PF04148.8 KII94920.1 - 4.1e-64 215.8 5.7 4.8e-64 215.5 4.0 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.3 KII94920.1 - 0.014 15.1 0.6 0.033 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) BTB PF00651.26 KII94921.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Syja_N PF02383.13 KII94922.1 - 1.1e-80 270.7 0.0 1.5e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KII94922.1 - 2.7e-27 96.2 0.1 5.2e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.3 KII94923.1 - 4e-70 235.3 0.1 4e-70 235.3 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KII94923.1 - 1.2e-07 31.0 0.1 2.9e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KII94923.1 - 2.2e-06 27.6 7.5 2.4e-06 27.5 1.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KII94923.1 - 6.8e-06 26.0 1.1 6.8e-06 26.0 0.8 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KII94923.1 - 0.001 19.1 0.8 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 KII94923.1 - 0.065 12.9 3.0 1.2 8.8 0.0 2.8 2 0 0 2 2 2 0 DBF zinc finger DUF951 PF06107.6 KII94923.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DEAD PF00270.24 KII94924.1 - 1.1e-41 142.1 0.2 2.1e-41 141.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KII94924.1 - 3.2e-27 94.1 0.2 7e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KII94924.1 - 0.01 15.5 0.2 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KII94924.1 - 0.019 14.8 0.0 0.063 13.1 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KII94924.1 - 0.027 14.5 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KII94924.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RRM_1 PF00076.17 KII94926.1 - 1.7e-18 66.0 0.1 1.7e-18 66.0 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII94926.1 - 2.8e-15 56.0 0.0 4.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII94926.1 - 9.2e-10 38.2 0.0 9.2e-10 38.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII94926.1 - 0.02 14.7 0.3 0.044 13.6 0.2 1.6 1 1 0 1 1 1 0 RNA binding motif Baculo_VP91_N PF08475.5 KII94928.1 - 0.027 13.8 1.4 0.032 13.5 0.9 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal RNA_pol_Rpb1_5 PF04998.12 KII94929.1 - 5.4e-87 291.5 0.1 8.1e-87 290.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KII94929.1 - 2.5e-61 206.4 0.2 2.8e-60 203.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KII94929.1 - 2e-36 125.0 0.0 6.6e-36 123.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KII94929.1 - 2.9e-30 105.6 5.3 9.1e-26 90.9 0.0 3.5 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KII94929.1 - 5.5e-21 74.3 0.0 1.5e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RIX1 PF08167.7 KII94932.1 - 2.5e-25 89.0 6.3 6.9e-25 87.6 0.7 2.3 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis Sec10 PF07393.6 KII94933.1 - 3.4e-228 759.4 0.1 4.4e-228 759.0 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Abhydrolase_3 PF07859.8 KII94934.1 - 3.4e-39 134.6 0.1 1.3e-30 106.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KII94934.1 - 4.8e-11 41.9 0.0 1.5e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KII94934.1 - 0.0008 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KII94934.1 - 0.11 11.2 0.1 0.43 9.2 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family Tubulin PF00091.20 KII94935.1 - 4.4e-68 229.3 0.0 5.7e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KII94935.1 - 1.1e-45 154.6 0.0 1.9e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KII94935.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Lipase_3 PF01764.20 KII94935.1 - 0.12 12.0 0.0 2 8.0 0.0 2.5 3 0 0 3 3 3 0 Lipase (class 3) Tubulin PF00091.20 KII94936.1 - 6.5e-67 225.4 0.0 8.6e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KII94936.1 - 3.2e-45 153.2 0.0 4.8e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KII94936.1 - 0.00097 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 KII94936.1 - 0.013 15.0 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) HAD_2 PF13419.1 KII94937.1 - 7.6e-12 45.7 0.0 1e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII94937.1 - 2.1e-10 40.1 0.0 4.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KII94937.1 - 0.00012 22.5 0.1 0.00038 20.9 0.0 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Sec15 PF04091.7 KII94938.1 - 5.8e-79 265.6 1.9 1.1e-78 264.7 1.3 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 KII94938.1 - 9.6e-08 32.0 0.6 9.6e-08 32.0 0.4 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KII94938.1 - 1.1e-06 28.3 0.2 1.1e-06 28.3 0.1 2.7 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 KII94938.1 - 6.8e-05 22.6 0.4 0.00027 20.6 0.0 2.2 3 0 0 3 3 3 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 KII94938.1 - 0.00013 21.5 2.4 0.00042 19.9 0.4 2.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Cortex-I_coil PF09304.5 KII94938.1 - 0.1 12.6 5.8 1.2 9.1 1.0 3.6 3 1 0 3 3 3 0 Cortexillin I, coiled coil Syntaxin PF00804.20 KII94938.1 - 0.18 11.9 6.8 0.7 10.0 0.2 3.2 2 1 0 2 2 2 0 Syntaxin COG2 PF06148.6 KII94938.1 - 0.49 10.2 11.7 0.029 14.2 0.9 3.7 5 1 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Arf PF00025.16 KII94939.1 - 3e-79 264.3 0.1 3.4e-79 264.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KII94939.1 - 2.4e-14 52.9 0.0 3e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KII94939.1 - 8.1e-13 48.0 0.0 8.9e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KII94939.1 - 3e-12 45.9 1.3 3.5e-09 35.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KII94939.1 - 4e-11 42.4 0.0 4.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KII94939.1 - 2.2e-09 37.8 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KII94939.1 - 5.2e-06 26.4 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KII94939.1 - 0.0068 15.4 0.5 0.014 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KII94939.1 - 0.007 15.8 0.1 0.061 12.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KII94939.1 - 0.056 13.3 0.2 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KII94939.1 - 0.13 11.7 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DSPc PF00782.15 KII94940.1 - 3.8e-29 100.9 0.0 4.6e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII94940.1 - 1.6e-06 27.6 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KII94940.1 - 0.023 13.5 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase DUF2076 PF09849.4 KII94942.1 - 0.049 13.6 3.0 0.071 13.1 2.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3245 PF11595.3 KII94943.1 - 3.5e-08 33.8 0.1 3.5e-08 33.8 0.1 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF3245) DUF2702 PF10863.3 KII94943.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2702) DUF1296 PF06972.6 KII94943.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Ebp2 PF05890.7 KII94943.1 - 2.8 7.1 16.3 0.73 9.0 3.8 3.3 3 0 0 3 3 3 0 Eukaryotic rRNA processing protein EBP2 SIP1 PF04938.7 KII94944.1 - 1.8e-11 43.8 2.7 1.4e-10 40.9 1.8 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Trypan_PARP PF05887.6 KII94944.1 - 9.7 6.0 10.3 20 4.9 7.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_7 PF13508.1 KII94945.1 - 1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII94945.1 - 3.7e-05 23.6 0.0 6.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KII94945.1 - 5.6e-05 22.8 0.0 0.0053 16.4 0.0 3.0 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_10 PF13673.1 KII94945.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KII94945.1 - 0.049 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CAP18_C PF12153.3 KII94945.1 - 0.089 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Acetyltransf_9 PF13527.1 KII94945.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GPI-anchored PF10342.4 KII94946.1 - 5.5e-15 55.6 1.2 8.6e-15 55.0 0.8 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family QRPTase_C PF01729.14 KII94947.1 - 5.4e-49 165.9 0.1 6.6e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KII94947.1 - 1.1e-22 79.6 0.0 2.8e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Methyltransf_11 PF08241.7 KII94948.1 - 6.7e-14 52.1 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII94948.1 - 6.7e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII94948.1 - 3.3e-06 26.9 0.0 4.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII94948.1 - 4.7e-06 26.6 0.0 8.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII94948.1 - 6.6e-06 26.4 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII94948.1 - 8.7e-05 22.9 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KII94949.1 - 1.3e-21 76.5 0.0 2.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII94949.1 - 4.6e-05 24.3 0.0 0.00016 22.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KII94949.1 - 0.0098 15.8 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Spermine_synth PF01564.12 KII94950.1 - 5.7e-08 32.0 0.0 8.8e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KII94950.1 - 0.0093 15.9 0.1 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 KII94950.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M28 PF04389.12 KII94951.1 - 8.5e-13 48.4 0.0 2.3e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KII94951.1 - 1e-12 47.6 0.1 6.3e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KII94951.1 - 1.2e-08 34.4 0.2 2.6e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 PA domain RNA_pol_I_TF PF04090.7 KII94953.1 - 7.5e-09 35.1 0.2 1.1e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_2 PF07719.12 KII94953.1 - 0.001 18.7 1.2 9.6 6.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII94953.1 - 0.0051 17.4 3.2 0.12 13.1 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII94953.1 - 0.0069 16.0 0.7 0.097 12.3 0.4 2.3 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.1 KII94953.1 - 0.079 13.3 1.1 8.4 6.8 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KII94953.1 - 0.089 12.9 0.1 1.4 9.1 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KII94953.1 - 0.72 10.6 5.3 26 5.8 0.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.22 KII94954.1 - 6.1e-41 139.9 2.0 6.7e-20 71.7 0.0 3.8 4 0 0 4 4 4 3 ABC transporter AAA_21 PF13304.1 KII94954.1 - 4.1e-16 59.7 7.3 0.00019 21.4 0.1 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KII94954.1 - 4.9e-13 48.8 0.2 0.0003 20.0 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KII94954.1 - 3e-09 36.2 1.9 0.00025 20.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 KII94954.1 - 7.7e-06 25.6 0.1 0.01 15.5 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KII94954.1 - 8.9e-06 26.5 0.5 0.0021 18.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran_2 PF12848.2 KII94954.1 - 7e-05 22.5 2.8 7e-05 22.5 1.9 1.8 2 0 0 2 2 1 1 ABC transporter AAA_23 PF13476.1 KII94954.1 - 8.3e-05 22.9 6.5 0.024 14.9 0.1 3.6 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 KII94954.1 - 0.00018 20.7 0.3 0.29 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KII94954.1 - 0.0003 20.3 0.4 1 8.6 0.1 3.2 3 0 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 KII94954.1 - 0.00041 20.2 1.1 0.21 11.5 0.1 3.2 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 KII94954.1 - 0.00054 19.1 0.3 0.097 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 KII94954.1 - 0.00085 19.4 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KII94954.1 - 0.0011 18.3 0.0 1.5 8.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KII94954.1 - 0.0012 18.5 0.1 1.2 8.7 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KII94954.1 - 0.0014 18.8 0.0 2.2 8.5 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KII94954.1 - 0.0021 18.3 0.1 0.074 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KII94954.1 - 0.0027 17.5 1.9 2.1 8.2 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KII94954.1 - 0.0032 17.4 4.3 0.69 9.8 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 KII94954.1 - 0.0032 17.4 1.1 1.3 8.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KII94954.1 - 0.0036 17.4 0.0 1 9.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KII94954.1 - 0.0078 16.1 0.1 3.7 7.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 KII94954.1 - 0.0079 16.0 2.9 2.7 7.7 0.0 2.9 3 1 0 3 3 3 2 Dynamin family Miro PF08477.8 KII94954.1 - 0.014 15.8 0.1 0.79 10.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 KII94954.1 - 0.038 13.4 0.1 0.77 9.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KII94954.1 - 0.062 12.1 0.5 2.2 7.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 KII94954.1 - 0.068 13.0 0.0 1 9.2 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KII94954.1 - 0.1 12.0 1.7 6.5 6.1 0.1 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 KII94954.1 - 0.11 10.9 5.4 3.2 6.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 KII94954.1 - 0.12 11.7 2.2 1.9 7.9 0.1 2.9 2 1 1 3 3 3 0 FtsK/SpoIIIE family Homez PF11569.3 KII94955.1 - 0.14 11.2 0.5 0.34 9.9 0.3 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ribonuclease PF00545.15 KII94956.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 ribonuclease Alpha-amylase_C PF02806.13 KII94957.1 - 3.4e-24 84.8 0.2 2.8e-23 81.8 0.0 2.5 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KII94957.1 - 2e-16 60.2 0.0 3.6e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 KII94957.1 - 7e-15 54.8 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CRAL_TRIO PF00650.15 KII94958.1 - 6.2e-39 133.0 0.0 8e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KII94958.1 - 4.8e-05 23.2 0.0 7.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RBD-FIP PF09457.5 KII94958.1 - 0.022 14.5 0.1 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 FIP domain CRAL_TRIO_N PF03765.10 KII94958.1 - 0.026 14.6 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain DUF3635 PF12330.3 KII94959.1 - 7.4e-20 70.8 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) DUF4470 PF14737.1 KII94960.1 - 1.3e-11 44.0 0.2 3.4e-11 42.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 KII94960.1 - 6.5e-07 28.9 1.3 1.8e-06 27.5 0.9 1.7 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 KII94960.1 - 0.021 15.4 0.6 0.021 15.4 0.4 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Enoyl_reductase PF12241.3 KII94960.1 - 0.041 12.8 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region TPR_12 PF13424.1 KII94960.1 - 0.082 12.8 0.9 0.18 11.7 0.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Snurportin1 PF11538.3 KII94961.1 - 0.019 14.6 2.0 0.041 13.6 1.4 1.5 1 0 0 1 1 1 0 Snurportin1 Sld5 PF05916.6 KII94962.1 - 1.1e-16 61.1 0.2 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 GINS complex protein P21-Arc PF04062.9 KII94964.1 - 6e-79 263.8 0.0 6.7e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.6 KII94965.1 - 2.1e-27 94.7 0.3 3.5e-27 94.0 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 KII94965.1 - 0.18 11.3 2.1 0.41 10.1 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF605 PF04652.11 KII94965.1 - 0.18 11.1 11.9 0.25 10.6 8.3 1.2 1 0 0 1 1 1 0 Vta1 like Iso_dh PF00180.15 KII94966.1 - 3.7e-125 417.4 0.0 4.3e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF904 PF06005.7 KII94967.1 - 0.027 14.7 17.4 0.17 12.1 3.6 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 KII94967.1 - 1.1 9.1 16.0 0.42 10.5 2.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TFR_dimer PF04253.10 KII94969.1 - 5.3e-15 55.0 0.0 1.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KII94969.1 - 9e-13 48.3 0.0 3.4e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KII94969.1 - 7.2e-06 25.6 0.1 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KII94969.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 GTP_cyclohydro2 PF00925.15 KII94970.1 - 3.2e-62 208.7 0.0 2.2e-56 189.7 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II KAR9 PF08580.5 KII94971.1 - 0.043 12.0 4.1 0.052 11.8 2.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Mucin PF01456.12 KII94971.1 - 7.6 6.3 21.3 26 4.5 12.4 2.1 1 1 1 2 2 2 0 Mucin-like glycoprotein Pex14_N PF04695.8 KII94972.1 - 1.3e-09 38.1 3.0 1.8e-09 37.7 0.0 2.7 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF86 PF01934.12 KII94972.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF86 Peptidase_M24 PF00557.19 KII94973.1 - 1.6e-14 54.0 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SKN1 PF03935.10 KII94974.1 - 9.3e-177 588.1 1.4 1.1e-176 587.9 1.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) adh_short PF00106.20 KII94976.1 - 1.5e-28 99.8 0.5 4.4e-28 98.2 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII94976.1 - 2.8e-12 46.6 0.8 6.2e-11 42.2 0.6 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII94976.1 - 8e-08 32.3 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII94976.1 - 0.0011 18.9 0.1 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII94976.1 - 0.098 12.0 0.2 0.15 11.4 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MerC PF03203.9 KII94976.1 - 0.6 10.4 3.2 5.1 7.5 0.0 2.9 3 0 0 3 3 3 0 MerC mercury resistance protein MFS_1 PF07690.11 KII94979.1 - 0.004 15.9 4.4 0.0048 15.6 3.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Herpes_UL20 PF04544.7 KII94979.1 - 0.0061 16.4 4.0 0.014 15.1 0.7 2.0 2 0 0 2 2 2 1 Herpesvirus egress protein UL20 PAP2 PF01569.16 KII94979.1 - 0.052 13.2 4.1 0.08 12.6 2.9 1.4 1 0 0 1 1 1 0 PAP2 superfamily HemY_N PF07219.8 KII94980.1 - 0.25 10.9 5.1 0.046 13.2 0.3 2.0 2 0 0 2 2 2 0 HemY protein N-terminus SSI PF00720.12 KII94983.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Subtilisin inhibitor-like F-box PF00646.28 KII94993.1 - 6.9e-05 22.3 0.2 0.00016 21.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KII94993.1 - 0.00036 20.2 0.2 0.00094 18.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.21 KII94994.1 - 7.5e-15 54.2 20.4 0.00011 22.3 1.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KII94994.1 - 3e-12 46.1 18.2 4.5e-06 26.6 0.3 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KII94994.1 - 4.4e-09 36.0 15.6 0.0015 18.7 0.6 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KII94994.1 - 0.0013 18.8 3.2 0.078 13.1 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KII94994.1 - 0.019 15.1 2.4 11 6.4 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KII94994.1 - 0.067 13.3 1.5 0.68 10.0 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KII94994.1 - 2.5 8.1 6.8 39 4.3 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger UCH PF00443.24 KII94995.1 - 2.8e-52 177.4 0.0 3.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KII94995.1 - 2.9e-27 95.9 0.0 8.6e-27 94.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KII94995.1 - 0.046 13.0 1.6 1.9 7.6 1.1 3.0 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase C1_4 PF07975.7 KII94995.1 - 0.44 10.5 2.8 16 5.5 0.1 3.1 3 0 0 3 3 3 0 TFIIH C1-like domain PP2C PF00481.16 KII94996.1 - 4.4e-26 91.8 0.0 2.3e-24 86.2 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 KII94996.1 - 4.7e-06 26.1 0.0 1.8e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C ACT_7 PF13840.1 KII94998.1 - 1.4e-18 66.1 0.0 9.5e-12 44.2 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KII94998.1 - 0.064 12.7 0.0 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 ACT domain DUF4653 PF15546.1 KII94998.1 - 0.99 8.6 9.4 0.2 10.9 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Cation_ATPase_C PF00689.16 KII94999.1 - 0.13 11.8 5.5 0.15 11.5 3.8 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4239 PF14023.1 KII94999.1 - 0.31 10.3 2.4 0.27 10.5 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3529 PF12046.3 KII94999.1 - 3.1 6.7 4.5 0.51 9.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) DNA_mis_repair PF01119.14 KII95000.1 - 2.2e-15 56.1 0.0 5.7e-14 51.5 0.0 2.6 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KII95000.1 - 1.3e-08 34.6 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KII95000.1 - 1.5e-06 27.8 0.0 3.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KII95000.1 - 0.0032 17.0 0.0 0.043 13.4 0.0 2.8 3 0 0 3 3 3 1 MutL C terminal dimerisation domain Carboxyl_trans PF01039.17 KII95001.1 - 4.6e-141 470.5 0.2 5.8e-141 470.2 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KII95001.1 - 0.00087 18.5 0.1 0.25 10.4 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ArfGap PF01412.13 KII95002.1 - 5.9e-33 113.1 0.0 1e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.8 KII95002.1 - 0.17 11.9 1.3 0.35 10.8 0.7 1.6 2 0 0 2 2 2 0 Piccolo Zn-finger Velvet PF11754.3 KII95003.1 - 2.4e-50 170.9 0.0 6e-49 166.4 0.0 2.1 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.1 KII95004.1 - 9.2e-38 127.9 0.8 1.1e-07 31.6 0.0 10.6 8 1 3 11 11 11 8 PPR repeat family PPR_3 PF13812.1 KII95004.1 - 6.8e-37 122.6 11.0 0.0019 18.3 0.0 14.5 14 0 0 14 14 14 8 Pentatricopeptide repeat domain PPR PF01535.15 KII95004.1 - 1.1e-29 100.2 7.4 0.072 13.0 0.0 13.8 15 0 0 15 15 15 8 PPR repeat PPR_1 PF12854.2 KII95004.1 - 6.7e-13 47.8 5.6 0.08 12.4 0.0 10.8 13 0 0 13 13 13 2 PPR repeat TPR_14 PF13428.1 KII95004.1 - 5.9e-08 32.6 17.3 3.5 8.5 0.2 10.3 8 4 4 12 12 12 3 Tetratricopeptide repeat GATase_6 PF13522.1 KII95004.1 - 1.3e-05 25.2 0.1 0.007 16.3 0.0 2.5 2 0 0 2 2 2 2 Glutamine amidotransferase domain TPR_16 PF13432.1 KII95004.1 - 0.00048 20.7 6.4 1.2 9.9 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII95004.1 - 0.028 14.7 4.1 15 5.9 0.0 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat Acetyltransf_5 PF13444.1 KII95005.1 - 2.5e-06 27.9 0.2 0.00012 22.6 0.0 2.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KII95005.1 - 2.9e-06 27.2 0.3 7.7e-06 25.8 0.1 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII95005.1 - 0.0039 17.3 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KII95005.1 - 0.09 12.8 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HMG_box PF00505.14 KII95006.1 - 4.4e-14 52.4 14.5 2.2e-06 27.8 2.2 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KII95006.1 - 4.9e-13 49.2 10.8 6.9e-06 26.3 2.8 2.7 2 1 0 2 2 2 2 HMG-box domain SAE2 PF08573.5 KII95006.1 - 5.4 7.7 6.7 1.4 9.6 0.3 2.6 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus GRIM-19 PF06212.7 KII95007.1 - 5e-29 100.6 0.0 5.9e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein SPX PF03105.14 KII95008.1 - 0.0025 17.6 0.0 0.011 15.5 0.0 1.9 1 1 1 2 2 2 1 SPX domain bZIP_1 PF00170.16 KII95008.1 - 0.27 11.2 2.8 0.53 10.2 2.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Bestrophin PF01062.16 KII95010.1 - 0.0085 15.0 0.1 0.0096 14.8 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3730 PF12530.3 KII95010.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Fer4 PF00037.22 KII95011.1 - 6.2e-14 50.9 17.4 1.8e-08 33.6 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KII95011.1 - 2.6e-12 46.9 10.8 4.4e-12 46.1 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KII95011.1 - 2.7e-10 39.8 22.5 1.4e-08 34.3 8.5 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 KII95011.1 - 7.3e-10 38.5 5.0 0.00011 21.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KII95011.1 - 1.1e-09 38.8 7.7 6.2e-05 23.6 0.4 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 KII95011.1 - 2.3e-09 37.3 11.2 4.4e-09 36.4 7.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KII95011.1 - 1.8e-08 34.2 19.7 1.3e-05 25.1 8.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KII95011.1 - 2.8e-08 33.2 15.2 7.4e-05 22.4 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KII95011.1 - 8.3e-08 31.7 18.0 0.00077 19.2 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KII95011.1 - 7.9e-07 29.3 27.7 0.00026 21.2 7.4 2.6 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 KII95011.1 - 1.3e-06 28.2 11.0 0.00038 20.5 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KII95011.1 - 9.4e-06 25.9 8.7 0.013 15.8 0.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KII95011.1 - 0.00017 21.8 11.6 0.037 14.4 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KII95011.1 - 0.0021 18.5 12.0 0.23 12.0 0.9 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 KII95011.1 - 0.02 14.9 4.3 0.038 14.1 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 KII95011.1 - 0.046 14.2 18.1 0.082 13.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Prefoldin_2 PF01920.15 KII95012.1 - 3.7e-21 74.8 0.1 4.5e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 KII95012.1 - 0.017 14.8 0.7 0.041 13.5 0.3 1.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 IncA PF04156.9 KII95012.1 - 0.055 13.0 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein CAP PF00188.21 KII95013.1 - 1e-16 61.5 2.5 1.6e-16 60.9 1.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GalP_UDP_transf PF01087.17 KII95013.1 - 0.11 12.5 0.4 0.23 11.5 0.3 1.6 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain TPR_11 PF13414.1 KII95014.1 - 1.5e-12 46.9 0.5 1.9e-09 37.0 0.2 2.7 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 KII95014.1 - 1.7e-11 44.7 0.0 3.7e-10 40.3 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 KII95014.1 - 1.8e-05 24.2 4.6 0.038 13.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII95014.1 - 0.00044 20.6 2.3 0.44 11.3 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KII95014.1 - 0.0022 17.8 1.6 0.18 11.7 0.5 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII95014.1 - 0.0023 18.5 8.0 0.047 14.3 2.9 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII95014.1 - 0.012 15.1 0.1 0.077 12.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KII95014.1 - 0.19 11.9 0.8 41 4.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 KII95015.1 - 8.9e-08 31.7 2.2 3e-07 30.0 1.5 2.0 1 0 0 1 1 1 1 F-box-like zf-C3HC4_2 PF13923.1 KII95016.1 - 3.5e-08 33.3 16.1 3.5e-08 33.3 11.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII95016.1 - 1.4e-06 27.8 21.8 6.3e-05 22.5 7.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII95016.1 - 7.5e-05 22.3 14.5 7.5e-05 22.3 10.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII95016.1 - 7.9e-05 22.3 22.4 0.00016 21.3 8.9 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII95016.1 - 0.00022 20.9 15.7 0.00022 20.9 10.9 3.2 3 0 0 3 3 3 1 Ring finger domain zf-Di19 PF05605.7 KII95016.1 - 0.72 10.0 8.4 6.3 7.0 0.4 3.6 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_6 PF14835.1 KII95016.1 - 0.81 9.5 16.5 0.086 12.6 5.7 2.8 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KII95016.1 - 6.4 6.7 21.2 1.6 8.6 8.3 3.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KII95020.1 - 9.2e-09 35.1 16.1 1.3e-08 34.7 11.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII95020.1 - 1.5e-05 24.6 11.4 2.2e-05 24.0 7.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII95020.1 - 1.9e-05 24.2 14.5 2.8e-05 23.6 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII95020.1 - 4.2e-05 23.1 12.8 5.8e-05 22.7 8.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KII95020.1 - 5.7e-05 22.8 15.7 8.1e-05 22.3 10.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 KII95020.1 - 0.015 14.8 6.6 0.023 14.2 4.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KII95020.1 - 0.016 14.9 8.3 0.03 14.1 5.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KII95020.1 - 0.17 11.8 11.9 0.74 9.7 8.5 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KII95020.1 - 2 8.2 11.1 1.2 8.8 3.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KII95020.1 - 2.9 7.5 14.7 9.9 5.8 10.2 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PgpA PF04608.8 KII95022.1 - 1.4 8.7 8.4 16 5.2 0.0 3.9 5 0 0 5 5 5 0 Phosphatidylglycerophosphatase A zf-C3HC4_2 PF13923.1 KII95023.1 - 3.9e-08 33.1 16.1 3.9e-08 33.1 11.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII95023.1 - 5.9e-07 29.0 21.4 7.1e-05 22.4 7.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII95023.1 - 2e-05 24.2 20.9 0.00018 21.1 8.9 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII95023.1 - 8.3e-05 22.1 14.5 8.3e-05 22.1 10.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII95023.1 - 0.00012 21.8 23.7 0.00025 20.8 10.9 3.2 3 0 0 3 3 3 1 Ring finger domain zf-Di19 PF05605.7 KII95023.1 - 0.027 14.5 8.6 2.3 8.4 0.6 4.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 KII95023.1 - 1 9.9 5.6 0.43 11.1 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-RING_6 PF14835.1 KII95023.1 - 1.2 9.0 16.5 0.1 12.3 5.7 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KII95023.1 - 2.6 7.9 19.8 1.8 8.5 8.3 3.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KII95023.1 - 5.6 6.5 17.2 0.1 12.1 5.0 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit EBV-NA1 PF02905.9 KII95027.1 - 0.12 11.8 0.6 1.1 8.7 0.0 1.9 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain PAS_7 PF12860.2 KII95028.1 - 0.081 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 PAS fold DUF569 PF04601.8 KII95029.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF569) zf-C3HC4_2 PF13923.1 KII95031.1 - 3.9e-08 33.2 16.1 3.9e-08 33.2 11.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII95031.1 - 5.1e-07 29.2 21.2 6.9e-05 22.4 7.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KII95031.1 - 1.6e-05 24.5 20.7 0.00017 21.2 8.9 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KII95031.1 - 8.2e-05 22.1 14.5 8.2e-05 22.1 10.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII95031.1 - 0.0001 22.0 23.6 0.00024 20.8 10.9 3.2 3 0 0 3 3 3 1 Ring finger domain zf-Di19 PF05605.7 KII95031.1 - 0.44 10.6 9.4 2.2 8.4 0.6 3.6 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 KII95031.1 - 0.9 10.1 5.8 0.37 11.3 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-RING_6 PF14835.1 KII95031.1 - 1 9.2 16.5 0.094 12.5 5.7 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KII95031.1 - 2.5 8.0 19.8 1.7 8.5 8.3 3.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KII95031.1 - 7.9 6.0 17.6 0.074 12.5 4.6 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Tom7 PF08038.7 KII95032.1 - 4.5e-17 61.2 0.3 5.1e-17 61.0 0.2 1.1 1 0 0 1 1 1 1 TOM7 family JAB PF01398.16 KII95033.1 - 5e-20 71.3 0.2 3e-19 68.8 0.1 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KII95033.1 - 8.5e-12 45.1 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.11 KII95034.1 - 2.6e-14 53.5 0.1 3.7e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 UreF AFG1_ATPase PF03969.11 KII95035.1 - 1.7e-96 323.2 0.0 1.4e-92 310.2 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 KII95035.1 - 0.0012 18.9 0.0 0.004 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KII95035.1 - 0.0019 18.4 0.0 0.0049 17.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KII95035.1 - 0.0029 17.6 0.2 0.18 11.7 0.0 2.8 1 1 2 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.13 KII95035.1 - 0.031 13.9 0.1 0.17 11.4 0.0 2.1 2 1 0 2 2 2 0 Bacterial dnaA protein Mg_chelatase PF01078.16 KII95035.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SBDS PF01172.13 KII95036.1 - 1.2e-15 57.0 0.0 1.5e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein F-box-like PF12937.2 KII95037.1 - 0.00013 21.5 3.3 0.00057 19.5 2.3 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KII95038.1 - 1.7e-07 30.8 0.6 4.6e-07 29.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like Y_phosphatase3 PF13350.1 KII95039.1 - 9.6e-44 149.5 0.0 1.2e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KII95039.1 - 3.4e-14 52.6 0.0 8.4e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KII95039.1 - 0.023 14.0 0.0 0.049 13.0 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Glyco_transf_7C PF02709.9 KII95039.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase MCM PF00493.18 KII95040.1 - 4.8e-137 456.1 0.3 6.6e-137 455.7 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KII95040.1 - 2.3e-22 79.7 0.0 4.9e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KII95040.1 - 1.1e-07 31.2 0.0 1.1e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KII95040.1 - 0.0023 17.4 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KII95040.1 - 0.0027 17.3 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KII95040.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_3 PF00933.16 KII95041.1 - 3.1e-84 282.4 0.0 4.5e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KII95041.1 - 8.7e-63 211.8 0.0 1.8e-61 207.5 0.0 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KII95041.1 - 1.6e-25 88.8 0.2 3.5e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KII95041.1 - 1.7e-06 27.7 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 KII95041.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 CARDB Vac14_Fig4_bd PF11916.3 KII95042.1 - 7.2e-82 272.9 5.5 1.2e-81 272.2 3.8 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KII95042.1 - 7.2e-40 135.2 0.0 1.7e-37 127.6 0.0 3.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KII95042.1 - 9.9e-13 47.0 3.4 0.0011 18.9 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 KII95042.1 - 1.8e-07 31.3 0.0 7.5 6.9 0.0 5.1 4 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KII95042.1 - 3.4e-06 27.3 0.8 5.7 7.5 0.0 6.7 6 1 1 7 7 7 1 HEAT-like repeat MMS19_C PF12460.3 KII95042.1 - 3.4e-05 22.7 3.7 0.057 12.1 0.0 3.4 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 KII95042.1 - 0.011 15.6 4.2 1.7 8.4 0.0 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KII95042.1 - 0.23 11.3 1.4 25 4.9 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat FH2 PF02181.18 KII95043.1 - 2.1e-86 290.1 1.0 1.1e-85 287.7 0.0 2.5 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KII95043.1 - 7e-29 100.5 2.0 2.4e-23 82.4 0.0 3.0 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KII95043.1 - 5.8e-22 78.0 0.1 1.8e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF2576 PF10845.3 KII95043.1 - 0.016 14.3 1.3 0.85 8.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) TMF_TATA_bd PF12325.3 KII95043.1 - 0.019 14.7 19.6 0.84 9.3 4.9 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 KII95043.1 - 0.092 12.4 19.6 0.14 11.9 0.8 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.1 KII95043.1 - 0.14 12.2 4.7 0.16 12.0 1.4 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Seryl_tRNA_N PF02403.17 KII95043.1 - 0.17 11.8 24.1 0.46 10.5 4.6 4.6 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Pox_A_type_inc PF04508.7 KII95043.1 - 0.53 10.2 7.8 5.9 6.9 0.0 4.2 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat TSC22 PF01166.13 KII95043.1 - 0.98 9.4 6.6 8.3 6.4 1.5 4.0 4 0 0 4 4 4 0 TSC-22/dip/bun family IU_nuc_hydro PF01156.14 KII95044.1 - 4.9e-93 311.7 0.0 5.5e-93 311.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RRN3 PF05327.6 KII95045.1 - 1.6e-164 548.1 0.1 3.4e-164 547.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3774 PF12609.3 KII95045.1 - 0.073 13.9 1.9 0.2 12.4 1.3 1.7 1 0 0 1 1 1 0 Wound-induced protein Corona_nucleoca PF00937.13 KII95045.1 - 0.19 10.6 5.7 0.3 9.9 3.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Nucleoplasmin PF03066.10 KII95045.1 - 7.3 6.0 18.8 0.023 14.2 0.9 2.4 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 KII95045.1 - 10 5.6 15.7 5.4 6.5 2.0 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Complex1_LYR PF05347.10 KII95046.1 - 9.7e-09 34.8 0.3 1.5e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KII95046.1 - 1.4e-06 28.3 0.6 2.1e-06 27.8 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like LNS2 PF08235.8 KII95047.1 - 1.9e-71 238.7 0.0 2.8e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KII95047.1 - 4.5e-31 106.7 0.0 1.3e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KII95047.1 - 0.045 13.1 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Nucleo_P87 PF07267.6 KII95047.1 - 0.5 8.9 7.3 0.94 8.0 5.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Lactamase_B_2 PF12706.2 KII95048.1 - 3.6e-08 33.1 0.1 7.5e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 KII95048.1 - 2.3e-07 30.8 0.0 5.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase TBX PF12598.3 KII95048.1 - 0.00051 20.3 1.3 0.096 13.0 0.1 2.8 2 0 0 2 2 2 2 T-box transcription factor Lactamase_B PF00753.22 KII95048.1 - 0.4 10.3 3.4 2.2 7.9 2.3 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily B3_4 PF03483.12 KII95049.1 - 1.2e-25 90.0 0.0 2.1e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KII95049.1 - 5.2e-19 67.8 0.0 4.7e-15 55.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 KII95049.1 - 0.004 16.3 0.0 0.041 13.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) Herpes_V23 PF01802.12 KII95049.1 - 0.11 11.5 0.1 0.24 10.3 0.1 1.5 1 1 0 1 1 1 0 Herpesvirus VP23 like capsid protein ATP_bind_4 PF01902.12 KII95050.1 - 1.1e-39 136.1 0.0 2.1e-30 105.7 0.0 2.1 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KII95050.1 - 4.8e-11 42.4 0.0 7.4e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Endoribonuclease L-PSP MFS_2 PF13347.1 KII95051.1 - 8.6e-09 34.2 6.2 8.6e-09 34.2 4.3 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein Reticulon PF02453.12 KII95051.1 - 0.046 13.3 0.1 0.046 13.3 0.1 3.0 3 0 0 3 3 3 0 Reticulon DUF2207 PF09972.4 KII95051.1 - 0.069 11.7 0.2 0.24 9.9 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1024 PF06260.7 KII95051.1 - 0.18 12.0 0.1 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Ank_2 PF12796.2 KII95052.1 - 4.5e-33 113.4 0.4 1.1e-17 64.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII95052.1 - 4.1e-26 90.8 2.7 1.5e-12 47.6 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KII95052.1 - 6.3e-20 69.9 1.4 4.6e-07 29.3 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KII95052.1 - 1.4e-17 63.3 1.6 1.4e-07 31.5 0.1 4.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII95052.1 - 9.3e-13 47.0 2.0 8.8e-05 22.3 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat FYRN PF05964.9 KII95053.1 - 0.092 12.2 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus CASP_C PF08172.7 KII95054.1 - 0.094 11.7 4.0 0.62 9.0 0.0 2.9 3 1 0 3 3 3 0 CASP C terminal DUF605 PF04652.11 KII95054.1 - 0.7 9.2 8.7 0.84 8.9 6.0 1.2 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 KII95054.1 - 2.3 6.5 8.0 3.4 6.0 5.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 KII95054.1 - 8.7 6.9 36.3 43 4.7 25.2 2.3 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glyco_hydro_18 PF00704.23 KII95055.1 - 5.9e-58 196.9 0.2 6.7e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COesterase PF00135.23 KII95056.1 - 9.1e-104 348.0 0.0 1.2e-103 347.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII95056.1 - 2.6e-08 33.6 0.3 1e-07 31.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold eRF1_1 PF03463.10 KII95057.1 - 3.7e-41 139.7 0.0 6.7e-41 138.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KII95057.1 - 5.3e-23 81.4 0.0 1e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KII95057.1 - 6.9e-19 68.5 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Thioredoxin PF00085.15 KII95058.1 - 0.0063 16.1 0.1 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KII95058.1 - 0.0069 15.1 0.1 0.009 14.7 0.0 1.3 1 0 0 1 1 1 1 Phosducin FAD_binding_7 PF03441.9 KII95059.1 - 7.6e-94 313.9 0.1 1.5e-93 313.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KII95059.1 - 7e-33 113.7 0.1 1.2e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase adh_short PF00106.20 KII95060.1 - 1.5e-18 67.2 0.3 2e-18 66.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII95060.1 - 1.3e-07 31.6 0.0 1.8e-07 31.1 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII95060.1 - 1.4e-07 31.3 0.0 1.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KII95060.1 - 5.3e-07 29.3 0.0 6.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KII95060.1 - 0.0027 17.1 0.1 0.043 13.2 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family F-box-like PF12937.2 KII95061.1 - 5.1e-05 22.9 0.0 0.00026 20.6 0.0 2.3 1 0 0 1 1 1 1 F-box-like DUF1793 PF08760.6 KII95062.1 - 2.7e-64 216.1 0.8 2.7e-64 216.1 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Glyco_hydro_28 PF00295.12 KII95065.1 - 1.5e-57 194.9 17.4 2.5e-57 194.3 12.0 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KII95065.1 - 6.8e-07 29.1 16.5 6.8e-07 29.1 11.4 2.8 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 KII95065.1 - 0.00022 20.4 8.2 0.00022 20.4 5.7 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) OMPdecase PF00215.19 KII95066.1 - 1.8e-70 236.8 0.0 2.4e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.13 KII95067.1 - 6.3e-68 229.1 0.0 4.2e-66 223.1 0.0 2.8 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) GRP PF07172.6 KII95067.1 - 1.7 9.1 12.9 3.4 8.2 3.2 2.6 2 0 0 2 2 2 0 Glycine rich protein family MFS_1 PF07690.11 KII95068.1 - 3.8e-32 111.3 23.5 1.9e-30 105.7 12.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII95068.1 - 2e-07 29.9 10.6 2e-07 29.9 7.4 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 KII95068.1 - 0.0017 17.1 0.3 0.0042 15.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 KII95068.1 - 0.0059 15.0 12.8 0.039 12.3 1.2 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF1129 PF06570.6 KII95068.1 - 0.13 11.5 2.8 1.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Cation_ATPase_C PF00689.16 KII95068.1 - 1.2 8.5 8.8 0.36 10.3 0.8 3.1 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus Rhomboid PF01694.17 KII95068.1 - 5.1 7.1 12.4 0.12 12.3 0.7 3.1 2 2 1 3 3 3 0 Rhomboid family Gly_transf_sug PF04488.10 KII95069.1 - 1.3e-21 76.9 0.1 2.3e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KII95069.1 - 0.0052 15.3 0.6 0.095 11.1 0.0 2.0 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain SusD-like_2 PF12771.2 KII95069.1 - 0.1 10.9 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane PIN_4 PF13638.1 KII95070.1 - 8.4e-21 74.4 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 PIN domain CTD_bind PF04818.8 KII95071.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRN7 PF11781.3 KII95071.1 - 0.19 11.2 0.5 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_L6 PF00347.18 KII95072.1 - 6.7e-30 103.4 3.2 3.8e-16 59.3 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CBM_4_9 PF02018.12 KII95072.1 - 0.012 15.6 0.1 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain DUF2117 PF09890.4 KII95072.1 - 0.038 13.1 0.8 0.05 12.7 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) ICMT PF04140.9 KII95073.1 - 1.9e-26 92.1 1.3 1.9e-26 92.1 0.9 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KII95073.1 - 3e-14 52.9 1.6 3e-14 52.9 1.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 KII95073.1 - 0.00031 20.1 0.9 0.00031 20.1 0.6 1.9 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.7 KII95073.1 - 0.00075 18.8 1.2 0.0013 18.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KII95073.1 - 0.0026 16.3 0.6 0.0036 15.9 0.4 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family GTP_EFTU PF00009.22 KII95074.1 - 7.5e-49 165.7 0.0 1.2e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KII95074.1 - 2.4e-14 52.9 0.0 3.5e-13 49.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KII95074.1 - 5.3e-13 48.6 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KII95074.1 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII95074.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAM219A PF15260.1 KII95075.1 - 0.0032 17.7 0.7 0.0057 16.9 0.5 1.3 1 0 0 1 1 1 1 Protein family FAM219A ADH_N PF08240.7 KII95079.1 - 2.2e-31 107.8 0.6 3.5e-31 107.1 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII95079.1 - 1.8e-23 82.5 0.0 2.9e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII95079.1 - 6.7e-08 33.4 0.1 1.5e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KII95079.1 - 0.00015 22.3 0.0 0.00032 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KII95079.1 - 0.019 14.3 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 KII95079.1 - 0.041 14.3 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KII95079.1 - 0.057 12.5 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 KII95079.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 KII95081.1 - 7.6e-21 74.1 65.0 1.4e-19 70.0 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KII95081.1 - 0.00018 20.0 1.8 0.00018 20.0 1.2 3.6 4 0 0 4 4 4 2 MFS/sugar transport protein DUF1228 PF06779.9 KII95081.1 - 0.0065 16.4 7.9 0.046 13.7 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Pkinase PF00069.20 KII95082.1 - 9e-56 188.8 0.0 1.2e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95082.1 - 1.4e-30 106.2 0.0 1.8e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII95082.1 - 9.2e-05 21.5 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KII95082.1 - 0.01 15.5 0.1 0.1 12.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CATSPERD PF15020.1 KII95082.1 - 0.099 10.6 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Meth_synt_2 PF01717.13 KII95083.1 - 3.1e-139 463.4 0.0 1.8e-135 451.0 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KII95083.1 - 2.9e-123 411.0 0.0 1.5e-110 369.3 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 KII95083.1 - 1.8 8.1 7.7 0.24 10.9 1.1 2.7 2 0 0 2 2 2 0 Short C-terminal domain PMSR PF01625.16 KII95084.1 - 4.2e-56 189.1 0.2 5.1e-56 188.8 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2985 PF11204.3 KII95087.1 - 3.6e-27 93.9 3.1 7.5e-27 92.9 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Apt1 PF10351.4 KII95088.1 - 8.9e-78 262.1 0.0 8.9e-78 262.1 0.0 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KII95088.1 - 2e-66 224.4 0.0 4.6e-66 223.1 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KII95088.1 - 1.2e-38 132.5 0.0 2.3e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KII95088.1 - 6.1e-18 65.0 0.0 2e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KII95088.1 - 1.8e-10 41.1 0.0 8.5e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.11 KII95089.1 - 5.5e-43 146.6 0.5 9.1e-43 145.9 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF1128 PF06569.6 KII95089.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Dpoe2NT PF12213.3 KII95089.1 - 0.094 12.6 0.5 0.23 11.3 0.4 1.6 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal UPF0183 PF03676.9 KII95090.1 - 1.8e-43 148.6 0.0 2.1e-42 145.1 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) HAD_2 PF13419.1 KII95091.1 - 8.6e-31 107.4 0.0 1e-30 107.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KII95091.1 - 1.1e-05 25.1 0.0 2.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KII95091.1 - 1.4e-05 25.6 0.0 0.00035 21.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KII95091.1 - 0.0036 16.9 0.0 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PNK3P PF08645.6 KII95091.1 - 0.064 12.6 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Ribosomal_L6e PF01159.14 KII95092.1 - 2.9e-37 127.2 0.1 4.6e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 KII95092.1 - 1.7e-08 34.1 0.1 1.7e-08 34.1 0.0 2.3 3 1 0 3 3 3 1 Ribosomal protein L6, N-terminal domain TonB_2 PF13103.1 KII95092.1 - 0.064 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 TonB C terminal TonB_C PF03544.9 KII95092.1 - 0.091 12.9 0.2 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal 60KD_IMP PF02096.15 KII95093.1 - 1.6e-21 76.9 0.0 5.4e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein DUF4381 PF14316.1 KII95093.1 - 0.83 9.7 5.2 0.57 10.2 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Clat_adaptor_s PF01217.15 KII95094.1 - 2.4e-56 189.4 1.2 2.8e-56 189.1 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_T PF00929.19 KII95095.1 - 2.1e-16 60.6 0.0 8.2e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Exonuclease CHORD PF04968.7 KII95095.1 - 0.02 15.0 3.4 0.053 13.7 2.4 1.7 1 0 0 1 1 1 0 CHORD TRAM_LAG1_CLN8 PF03798.11 KII95096.1 - 2.2e-30 105.7 23.4 4.6e-30 104.6 16.2 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KII95096.1 - 1.8e-13 49.7 0.2 5.5e-13 48.2 0.2 1.9 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KII95097.1 - 4.6e-27 94.8 25.6 4.6e-27 94.8 17.7 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KII95097.1 - 9.8e-11 41.0 0.1 9.8e-11 41.0 0.1 2.4 3 0 0 3 3 3 1 TRAM1-like protein Ad_cyc_g-alpha PF08509.6 KII95098.1 - 0.066 12.5 0.2 0.18 11.1 0.1 1.7 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain Histone PF00125.19 KII95099.1 - 1.4e-29 102.0 0.2 1.9e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KII95099.1 - 0.00067 19.7 0.1 0.00098 19.2 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KII95099.1 - 0.013 15.5 0.9 0.023 14.7 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KII95099.1 - 0.02 14.1 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T adh_short PF00106.20 KII95100.1 - 4.7e-18 65.6 0.2 7.1e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII95100.1 - 0.0001 22.0 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII95100.1 - 0.00033 20.3 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CENP-B_dimeris PF09026.5 KII95101.1 - 2.2 8.5 6.0 5.3 7.3 4.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain OB_RNB PF08206.6 KII95102.1 - 0.071 12.6 0.7 0.086 12.3 0.5 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain DnaJ PF00226.26 KII95104.1 - 2.1e-17 62.5 0.0 3.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.8 KII95104.1 - 0.0092 16.3 4.2 0.56 10.6 0.0 3.4 3 1 0 3 3 3 1 Oxaloacetate decarboxylase, gamma chain Antimicrobial10 PF08105.6 KII95104.1 - 0.14 11.7 0.0 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Metchnikowin family Gln-synt_C PF00120.19 KII95105.1 - 2.4e-61 207.1 0.0 2.9e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KII95105.1 - 7.3e-19 67.1 0.0 1.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Iso_dh PF00180.15 KII95107.1 - 2.1e-78 263.7 0.0 2.5e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 KII95108.1 - 1.6e-06 28.1 0.0 1.5e-05 25.0 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII95108.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Vasculin PF15337.1 KII95108.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Methyltransf_33 PF10017.4 KII95109.1 - 4.1e-32 110.7 0.0 4.9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF3714 PF12508.3 KII95111.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3714) Sugar_tr PF00083.19 KII95112.1 - 9e-20 70.6 32.0 6.2e-13 48.1 6.4 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KII95112.1 - 6.4e-14 51.4 33.0 6.4e-14 51.4 22.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KII95112.1 - 0.29 9.4 27.1 0.021 13.2 3.7 3.7 1 1 2 3 3 3 0 MFS/sugar transport protein zf-MYND PF01753.13 KII95113.1 - 7.5e-11 41.7 9.9 1.3e-10 40.9 6.8 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 KII95114.1 - 0.05 13.3 0.4 0.05 13.3 0.3 2.1 2 0 0 2 2 2 0 F-box-like Amidohydro_2 PF04909.9 KII95115.1 - 6e-27 94.8 0.5 7.3e-27 94.6 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Strep_SA_rep PF06696.6 KII95115.1 - 1.2 9.0 7.7 0.083 12.6 1.2 2.1 2 0 0 2 2 2 0 Streptococcal surface antigen repeat adh_short PF00106.20 KII95116.1 - 5.9e-32 110.8 0.2 9.4e-32 110.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII95116.1 - 1.3e-16 61.1 0.0 1.7e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII95116.1 - 3.9e-14 52.7 1.2 1.7e-13 50.6 0.8 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII95116.1 - 0.00047 20.2 0.3 0.00068 19.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII95116.1 - 0.0012 18.3 0.1 0.0093 15.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KII95116.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KII95116.1 - 0.067 12.4 0.4 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 KII95116.1 - 0.14 10.8 0.1 0.35 9.5 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Transket_pyr PF02779.19 KII95117.1 - 5.7e-48 162.7 0.0 1.2e-47 161.6 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KII95117.1 - 2.1e-40 137.4 0.1 5.3e-40 136.2 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Histidinol_dh PF00815.15 KII95118.1 - 5.5e-174 578.6 1.3 7.5e-174 578.1 0.9 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KII95118.1 - 3.3e-25 87.5 0.3 6.7e-25 86.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KII95118.1 - 2.3e-08 34.1 1.8 6.6e-08 32.7 0.1 2.5 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KII95118.1 - 0.01 15.7 0.6 0.024 14.5 0.4 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Val_tRNA-synt_C PF10458.4 KII95119.1 - 0.03 14.4 0.5 0.053 13.6 0.4 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm AKNA PF12443.3 KII95119.1 - 0.08 12.9 0.1 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor TBPIP PF07106.8 KII95119.1 - 0.081 12.4 0.7 0.09 12.3 0.5 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TspO_MBR PF03073.10 KII95120.1 - 3.9e-39 133.5 8.4 4.5e-39 133.3 5.9 1.0 1 0 0 1 1 1 1 TspO/MBR family Glyco_hydro_16 PF00722.16 KII95121.1 - 9.3e-09 34.8 0.1 1.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 KII95121.1 - 0.0072 15.8 0.5 0.017 14.6 0.3 1.6 1 0 0 1 1 1 1 Adenoviral fibre protein (repeat/shaft region) Piwi PF02171.12 KII95122.1 - 7.9e-89 297.5 0.0 1.2e-88 297.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KII95122.1 - 2.7e-14 52.2 0.2 7.6e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KII95122.1 - 1.5e-06 27.5 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Mito_carr PF00153.22 KII95124.1 - 2e-65 216.4 2.4 3e-22 78.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 KII95124.1 - 0.002 17.8 0.1 0.028 14.2 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KII95124.1 - 0.0039 17.2 0.1 0.015 15.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KII95124.1 - 0.0084 15.3 2.7 0.018 14.3 0.0 2.9 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 KII95124.1 - 0.037 13.3 0.2 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 EF hand Pkinase PF00069.20 KII95126.1 - 3.4e-39 134.5 0.0 7.2e-39 133.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95126.1 - 3.3e-36 124.6 0.0 2.1e-35 122.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII95126.1 - 1.7e-06 27.2 0.0 6.3e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KII95126.1 - 0.028 14.1 0.1 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KII95126.1 - 0.033 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KII95126.1 - 0.048 12.7 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPR_2 PF13041.1 KII95127.1 - 0.13 12.2 0.8 7.5 6.6 0.0 2.5 2 1 0 2 2 2 0 PPR repeat family SNARE_assoc PF09335.6 KII95128.1 - 6.7e-16 58.6 3.4 6.7e-16 58.6 2.4 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Ribosomal_L36e PF01158.13 KII95130.1 - 3.9e-39 132.5 3.9 4.4e-39 132.4 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e INT_SG_DDX_CT_C PF15300.1 KII95130.1 - 0.11 11.9 0.8 0.25 10.8 0.0 1.9 2 1 1 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus CK_II_beta PF01214.13 KII95131.1 - 1.9e-75 252.3 0.0 2.7e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.8 KII95131.1 - 0.014 14.9 2.0 0.014 14.9 1.4 1.6 2 0 0 2 2 2 0 YL1 nuclear protein CENP-T PF15511.1 KII95131.1 - 2.9 7.0 19.5 0.014 14.6 5.8 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T CRCB PF02537.10 KII95132.1 - 2.2e-32 111.3 14.0 1.2e-19 70.2 2.9 2.3 2 0 0 2 2 2 2 CrcB-like protein Rab5ip PF07019.7 KII95132.1 - 0.5 10.5 7.3 0.15 12.2 1.2 2.7 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Med17 PF10156.4 KII95133.1 - 2.1e-43 148.3 0.0 2.7e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PepX_C PF08530.5 KII95133.1 - 0.0015 18.4 0.2 0.17 11.7 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Fungal_trans PF04082.13 KII95134.1 - 1e-17 63.8 0.0 1.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII95134.1 - 3.9e-05 23.4 10.1 5.9e-05 22.8 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.4 KII95135.1 - 4.8e-14 52.6 2.3 6.5e-14 52.1 1.6 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CD36 PF01130.16 KII95135.1 - 0.14 10.4 0.1 0.17 10.1 0.1 1.1 1 0 0 1 1 1 0 CD36 family Snf7 PF03357.16 KII95136.1 - 4.6e-29 100.9 21.0 4.6e-29 100.9 14.5 1.4 1 1 0 1 1 1 1 Snf7 Iso_dh PF00180.15 KII95137.1 - 1.4e-100 336.6 0.0 1.8e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.14 KII95138.1 - 1.9e-95 319.8 0.0 3.9e-95 318.8 0.0 1.5 1 0 0 1 1 1 1 RNB domain BTB_2 PF02214.17 KII95139.1 - 0.1 12.8 0.0 0.51 10.5 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain FeS PF04060.8 KII95140.1 - 0.12 12.0 0.7 7.4 6.2 0.1 2.3 2 0 0 2 2 2 0 Putative Fe-S cluster DUF4588 PF15251.1 KII95140.1 - 7.8 6.3 8.8 11 5.8 5.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4588) RTA1 PF04479.8 KII95141.1 - 4.3e-40 137.6 2.5 5.8e-40 137.1 1.7 1.1 1 0 0 1 1 1 1 RTA1 like protein VID27 PF08553.5 KII95143.1 - 8.4e-253 841.1 6.8 2e-250 833.3 4.7 2.0 1 1 0 1 1 1 1 VID27 cytoplasmic protein Nuf2 PF03800.9 KII95143.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuf2 family DUF2834 PF11196.3 KII95144.1 - 0.092 12.9 0.3 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) adh_short PF00106.20 KII95145.1 - 3.1e-19 69.5 0.7 4.8e-19 68.8 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII95145.1 - 5.5e-09 35.9 0.4 1e-08 35.0 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII95145.1 - 0.00066 19.5 0.0 0.00089 19.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII95145.1 - 0.0052 16.8 0.2 0.032 14.2 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII95145.1 - 0.0061 16.0 0.0 0.049 13.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 KII95145.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus ADH_zinc_N PF00107.21 KII95145.1 - 0.05 13.1 0.1 0.19 11.2 0.1 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 KII95145.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KII95145.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA_16 PF13191.1 KII95146.1 - 1.3e-10 41.5 0.1 3.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KII95146.1 - 3.1e-07 30.1 0.0 8.7e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 NACHT domain WD40 PF00400.27 KII95146.1 - 5e-07 29.3 0.9 0.43 10.5 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KII95146.1 - 0.00018 21.0 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain AAA PF00004.24 KII95146.1 - 0.0027 17.9 0.0 0.01 16.0 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KII95146.1 - 0.0087 15.7 0.0 0.036 13.7 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase ArgK PF03308.11 KII95146.1 - 0.014 14.1 0.1 0.066 11.9 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_22 PF13401.1 KII95146.1 - 0.015 15.3 0.0 0.072 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF919 PF06034.6 KII95146.1 - 0.023 14.2 0.3 0.39 10.3 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PD40 PF07676.7 KII95146.1 - 0.092 12.4 4.8 96 2.8 0.1 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 KII95146.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 KII95146.1 - 0.14 12.4 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KII95146.1 - 0.19 10.8 0.0 0.4 9.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KII95146.1 - 0.25 11.6 0.0 0.71 10.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Proteasome_A_N PF10584.4 KII95146.1 - 0.54 9.6 11.5 1.8 7.9 0.7 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ribosomal_L18p PF00861.17 KII95147.1 - 1.5e-42 144.5 0.1 5.3e-42 142.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KII95147.1 - 4.7e-33 113.6 2.6 4.7e-33 113.6 1.8 1.9 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region MtrA PF04208.9 KII95147.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A RRM_1 PF00076.17 KII95148.1 - 1.7e-15 56.3 0.1 2.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII95148.1 - 3.3e-10 39.8 0.0 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95148.1 - 0.00096 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WH2 PF02205.15 KII95149.1 - 2.3e-06 27.0 2.9 6.8e-06 25.5 1.1 2.4 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.15 KII95150.1 - 7.9e-59 195.7 0.0 3.1e-31 107.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KII95150.1 - 3.2e-43 147.6 0.0 1.2e-32 113.1 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KII95150.1 - 1.1e-10 41.4 0.2 0.00038 20.4 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KII95150.1 - 1.7e-10 41.0 1.1 0.001 19.2 0.0 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII95150.1 - 6.2e-10 39.0 0.8 0.011 15.8 0.0 3.9 4 1 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 KII95150.1 - 1.1e-05 24.4 0.1 3.5e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 KII95150.1 - 0.00014 21.5 0.3 0.3 10.7 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KII95150.1 - 0.00053 19.5 1.5 1.4 8.4 0.0 3.4 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 KII95150.1 - 0.0018 18.2 0.1 3.4 7.6 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 KII95150.1 - 0.013 15.3 0.0 0.097 12.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.19 KII95150.1 - 0.066 13.2 1.2 2.5 8.1 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin TCTP PF00838.12 KII95152.1 - 2.3e-73 245.6 1.4 2.5e-73 245.4 1.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.5 KII95153.1 - 1.7e-48 164.0 0.0 2.7e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KII95153.1 - 1.7e-28 97.4 2.8 5.9e-07 29.1 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KII95153.1 - 0.0029 15.9 0.0 0.031 12.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KII95153.1 - 0.0052 15.6 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region CTNNBL PF08216.6 KII95154.1 - 3.8e-28 97.2 0.0 1.3e-27 95.4 0.0 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 KII95154.1 - 0.0054 16.9 3.1 1.8 8.8 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats Arm PF00514.18 KII95154.1 - 0.074 12.8 0.2 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PCI PF01399.22 KII95157.1 - 2.3e-10 40.7 0.0 6.9e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KII95157.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Cohesin_load PF10345.4 KII95157.1 - 0.051 11.7 0.1 0.079 11.1 0.1 1.2 1 0 0 1 1 1 0 Cohesin loading factor TPR_12 PF13424.1 KII95157.1 - 0.051 13.5 2.2 0.35 10.8 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TAFH PF07531.9 KII95157.1 - 0.079 12.6 0.5 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 NHR1 homology to TAF TPR_14 PF13428.1 KII95157.1 - 0.36 11.6 3.6 11 6.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CHZ PF09649.5 KII95158.1 - 0.25 10.5 3.5 0.4 9.9 2.4 1.3 1 0 0 1 1 1 0 Histone chaperone domain CHZ Pkinase PF00069.20 KII95159.1 - 2.1e-75 253.2 0.0 2.5e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95159.1 - 2.7e-38 131.5 0.0 3.7e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII95159.1 - 5.2e-07 28.9 0.0 1.1e-05 24.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KII95159.1 - 0.019 14.0 0.2 0.056 12.5 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 KII95160.1 - 1.1e-23 82.1 8.6 3.7e-11 42.4 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat TRAP_alpha PF03896.11 KII95160.1 - 0.39 9.6 1.8 0.6 9.0 1.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Asp PF00026.18 KII95161.1 - 1.4e-109 366.2 0.5 1.6e-109 366.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII95161.1 - 4.1e-11 43.1 0.0 8.2e-11 42.1 0.0 1.5 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII95161.1 - 6.2e-07 29.8 0.2 0.0048 17.3 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KII95161.1 - 8.1e-07 28.7 0.0 1.5e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Bromodomain PF00439.20 KII95162.1 - 7.6e-25 86.6 0.1 1.5e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 Bromodomain FAT PF02259.18 KII95163.1 - 3.6e-68 230.1 7.2 6.5e-68 229.2 5.0 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KII95163.1 - 7.7e-16 58.2 0.0 2e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HEAT PF02985.17 KII95163.1 - 0.0023 17.8 0.5 9.8 6.5 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Glycolytic PF00274.14 KII95163.1 - 0.11 10.9 0.2 0.3 9.4 0.0 1.8 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-I DUF4041 PF13250.1 KII95163.1 - 0.25 10.9 0.1 0.72 9.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) PUB PF09409.5 KII95164.1 - 8.2e-10 38.3 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PUB domain DUF3759 PF12585.3 KII95165.1 - 4.7e-37 125.7 10.3 5.4e-37 125.5 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SRP40_C PF05022.7 KII95165.1 - 0.024 15.0 0.9 0.045 14.2 0.0 1.8 1 1 1 2 2 2 0 SRP40, C-terminal domain DUF1310 PF07006.6 KII95165.1 - 0.54 9.7 2.5 0.23 10.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1310) DUF3336 PF11815.3 KII95167.1 - 1.7e-40 137.8 3.0 2.7e-40 137.1 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KII95167.1 - 1.4e-21 77.3 0.1 3.3e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase BCDHK_Adom3 PF10436.4 KII95169.1 - 5e-42 143.2 0.0 7.1e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KII95169.1 - 2.8e-14 52.7 0.0 9.7e-14 51.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KII95169.1 - 0.0007 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KII95169.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain Med20 PF08612.6 KII95170.1 - 2.9e-09 36.4 0.0 1.4e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex AAA_16 PF13191.1 KII95171.1 - 7.7e-22 78.1 0.1 2.3e-21 76.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.1 KII95171.1 - 9.8e-22 77.3 0.0 1.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.24 KII95171.1 - 0.00094 19.3 0.0 0.0058 16.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KII95171.1 - 0.0098 15.5 0.1 0.14 11.7 0.1 2.3 1 1 0 1 1 1 1 NACHT domain RNA12 PF10443.4 KII95171.1 - 0.013 13.9 0.0 1.1 7.6 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein AAA_22 PF13401.1 KII95171.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII95171.1 - 0.022 14.6 0.0 0.13 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KII95171.1 - 0.033 13.9 0.0 0.081 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KII95171.1 - 0.047 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KII95171.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain LON PF02190.11 KII95172.1 - 1.9e-21 76.7 0.0 2.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 KII95172.1 - 3.9e-10 39.4 26.8 4.4e-05 23.2 7.9 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KII95172.1 - 2.3e-09 37.1 30.1 1.5e-06 28.1 8.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII95172.1 - 4.3e-09 35.8 26.7 4.8e-07 29.3 8.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII95172.1 - 6.8e-09 35.2 24.0 8.8e-08 31.7 5.4 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII95172.1 - 2.6e-08 33.5 29.9 3.8e-08 33.0 9.5 2.7 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KII95172.1 - 1.5e-07 31.0 27.4 5.4e-07 29.2 7.7 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 KII95172.1 - 0.00038 20.1 15.7 0.021 14.6 2.5 2.4 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KII95172.1 - 0.00097 18.8 21.5 0.026 14.2 5.0 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.1 KII95172.1 - 0.015 14.8 7.1 0.015 14.8 4.9 3.0 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KII95172.1 - 0.14 12.0 2.6 0.49 10.2 1.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 KII95172.1 - 1.2 8.6 14.4 0.042 13.3 4.8 2.4 2 0 0 2 2 2 0 P-11 zinc finger Polysacc_deac_1 PF01522.16 KII95173.1 - 3.3e-21 75.1 0.0 8.5e-21 73.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF1682 PF07946.9 KII95175.1 - 3.5e-65 219.9 0.0 3.9e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SCFA_trans PF02667.9 KII95175.1 - 0.16 10.6 1.2 3 6.4 0.1 2.1 2 0 0 2 2 2 0 Short chain fatty acid transporter NdhN PF11909.3 KII95176.1 - 0.052 12.8 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N DUF3818 PF12825.2 KII95177.1 - 1.3e-116 389.0 0.1 1.8e-116 388.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KII95177.1 - 1.6e-27 95.8 0.1 6e-27 93.9 0.0 2.1 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KII95177.1 - 6.3e-11 42.0 0.1 2.6e-10 40.0 0.1 2.1 1 0 0 1 1 1 1 PX domain Sigma70_ner PF04546.8 KII95177.1 - 6 6.4 17.7 0.079 12.5 5.1 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region DEAD PF00270.24 KII95178.1 - 7.4e-37 126.4 0.0 1.9e-36 125.1 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KII95178.1 - 1.7e-23 81.9 0.2 3.2e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KII95178.1 - 1.7e-18 66.2 0.0 4.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII95178.1 - 0.00046 20.0 0.5 0.0017 18.2 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KII95178.1 - 0.023 14.4 0.0 0.1 12.3 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain TT_ORF2 PF02957.10 KII95178.1 - 4.6 7.9 9.5 10 6.8 6.4 1.7 1 1 0 1 1 1 0 TT viral ORF2 UPF0184 PF03670.8 KII95179.1 - 0.19 11.9 6.2 20 5.4 2.9 3.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) Prominin PF05478.6 KII95179.1 - 0.6 7.5 2.7 0.91 6.9 1.9 1.3 1 0 0 1 1 1 0 Prominin DUF603 PF04645.7 KII95179.1 - 0.68 9.8 11.4 0.47 10.3 0.3 3.6 1 1 2 3 3 3 0 Protein of unknown function, DUF603 Ribosomal_L7Ae PF01248.21 KII95180.1 - 4e-25 87.1 2.1 8.6e-25 86.0 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1979 PF09322.5 KII95181.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Cupin_8 PF13621.1 KII95182.1 - 3.6e-58 197.0 0.0 5e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KII95182.1 - 0.0019 17.6 0.3 0.033 13.6 0.1 2.4 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.17 KII95182.1 - 0.0039 17.4 0.1 0.023 14.9 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KII95182.1 - 0.09 12.0 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Cupin superfamily protein AAA PF00004.24 KII95183.1 - 3.6e-06 27.2 0.7 3.5e-05 24.0 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KII95183.1 - 0.00034 20.2 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KII95183.1 - 0.00077 18.2 0.1 0.012 14.3 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KII95183.1 - 0.0024 17.8 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KII95183.1 - 0.019 15.7 0.1 0.07 13.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KII95183.1 - 0.026 14.6 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KII95183.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KII95183.1 - 0.056 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KII95183.1 - 0.18 10.7 0.2 2.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.8 KII95183.1 - 0.32 9.6 0.0 0.52 8.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus HLH PF00010.21 KII95184.1 - 1.4e-13 50.3 0.2 2.8e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 KII95185.1 - 7.5e-64 215.3 0.0 1.5e-42 145.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII95185.1 - 4.3e-28 98.0 0.0 4.4e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KII95185.1 - 9.8e-05 21.4 0.2 0.00023 20.2 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KII95185.1 - 0.00036 19.6 0.0 0.00095 18.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KII95185.1 - 0.00099 19.5 0.5 0.0022 18.4 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 KII95185.1 - 0.0037 17.0 1.4 0.019 14.7 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII95185.1 - 0.022 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KII95185.1 - 0.027 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KII95185.1 - 0.033 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Aconitase PF00330.15 KII95187.1 - 6.7e-11 41.3 4.3 9.7e-09 34.2 0.8 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) F-box-like PF12937.2 KII95188.1 - 0.093 12.4 0.5 0.2 11.4 0.4 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KII95189.1 - 0.016 14.9 0.3 0.032 13.9 0.2 1.5 1 0 0 1 1 1 0 F-box-like LRR_2 PF07723.8 KII95189.1 - 0.13 12.8 0.9 1.9 9.1 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat UQ_con PF00179.21 KII95190.1 - 1.2e-37 128.4 0.1 1.5e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KII95190.1 - 0.12 12.0 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain FimP PF09766.4 KII95191.1 - 4.7e-34 118.0 14.3 5.6e-34 117.7 9.9 1.0 1 0 0 1 1 1 1 Fms-interacting protein Paf67 PF10255.4 KII95191.1 - 0.076 11.8 2.0 0.1 11.4 1.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 DUF3540 PF12059.3 KII95191.1 - 0.61 9.6 6.0 0.41 10.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Pro_CA PF00484.14 KII95191.1 - 1 9.3 4.4 1 9.3 0.6 2.0 2 0 0 2 2 2 0 Carbonic anhydrase CENP-F_leu_zip PF10473.4 KII95191.1 - 1.2 9.0 15.9 2.5 7.9 6.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 KII95191.1 - 1.2 9.0 16.5 0.47 10.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CpG_bind_C PF12269.3 KII95191.1 - 1.8 7.9 6.9 1.1 8.7 0.3 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF948 PF06103.6 KII95191.1 - 3.8 7.4 5.9 18 5.3 3.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.3 KII95191.1 - 4.4 6.4 16.3 4.6 6.4 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF607 PF04678.8 KII95191.1 - 6.6 6.6 6.6 8.6 6.2 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 G6PD_C PF02781.11 KII95192.1 - 9.6e-124 411.9 0.0 1.4e-123 411.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KII95192.1 - 1.3e-62 211.2 0.0 2e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KII95192.1 - 0.13 12.8 0.0 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F-box-like PF12937.2 KII95194.1 - 0.00056 19.5 0.2 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_M50 PF02163.17 KII95196.1 - 0.1 11.5 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M50 Fig1 PF12351.3 KII95196.1 - 4.3 7.1 9.0 6.1 6.6 6.3 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 PMP22_Claudin PF00822.15 KII95197.1 - 0.33 10.5 7.2 0.093 12.3 2.9 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2721 PF11026.3 KII95197.1 - 4 7.0 14.5 0.18 11.4 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) AMP-binding PF00501.23 KII95198.1 - 6.5e-41 140.0 0.0 9.2e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Metallophos PF00149.23 KII95200.1 - 2.3e-12 46.7 0.5 3.7e-12 46.0 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RFX_DNA_binding PF02257.10 KII95201.1 - 1.6e-25 89.0 0.0 3.2e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain PPR_2 PF13041.1 KII95203.1 - 3.1e-19 68.6 0.1 3.6e-11 42.8 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 KII95203.1 - 2.2e-10 39.7 1.3 0.037 14.0 0.0 6.8 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.1 KII95203.1 - 3.1e-07 30.1 8.3 0.023 14.9 0.0 7.2 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 KII95203.1 - 1.8e-05 24.1 0.0 0.5 9.8 0.1 4.1 4 0 0 4 4 4 2 PPR repeat Asp PF00026.18 KII95204.1 - 2e-33 115.9 0.1 2.4e-32 112.4 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII95204.1 - 0.00028 20.8 2.5 0.0011 18.9 0.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Herpes_gE PF02480.11 KII95204.1 - 0.0064 14.8 0.0 0.0098 14.1 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KII95204.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Fe-ADH PF00465.14 KII95205.1 - 1.9e-90 303.1 0.0 2.5e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KII95205.1 - 3.2e-11 43.0 0.1 1.8e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase His_biosynth PF00977.16 KII95206.1 - 4.7e-36 124.1 0.0 6.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_L29 PF00831.18 KII95207.1 - 1.8e-19 69.1 1.0 1.8e-19 69.1 0.7 2.0 2 1 1 3 3 3 1 Ribosomal L29 protein MRP-L47 PF06984.8 KII95207.1 - 0.044 13.6 0.3 0.15 11.9 0.2 1.9 1 1 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Pkinase PF00069.20 KII95208.1 - 1.2e-69 234.3 0.0 1.7e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95208.1 - 3.5e-47 160.6 0.0 4.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII95208.1 - 4.9e-05 22.4 0.0 0.00092 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Polysacc_deac_1 PF01522.16 KII95210.1 - 3.5e-25 88.0 0.0 1.6e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 KII95212.1 - 2.6e-19 69.0 0.2 1.3e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase DNA_pol_viral_N PF00242.12 KII95212.1 - 5.7 5.8 9.1 8.2 5.3 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TFIIF_alpha PF05793.7 KII95213.1 - 2.5e-12 45.9 52.0 5.3e-06 25.1 1.3 3.9 3 1 0 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 KII95213.1 - 1.4 7.3 16.8 2.4 6.5 11.7 1.4 1 0 0 1 1 1 0 Daxx Family Ribophorin_I PF04597.9 KII95215.1 - 3.6e-119 398.1 0.0 4.4e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.14 KII95216.1 - 1.4e-19 69.9 0.1 2.4e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_C10 PF01640.12 KII95216.1 - 0.051 13.3 0.1 0.071 12.8 0.1 1.4 1 1 0 1 1 1 0 Peptidase C10 family GILT PF03227.11 KII95217.1 - 4.5e-10 39.3 0.2 4.5e-10 39.3 0.1 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Yos1 PF08571.5 KII95218.1 - 1.9e-27 95.1 0.1 2.3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Yos1-like Cid2 PF09774.4 KII95219.1 - 3.6e-27 95.3 3.8 1.1e-26 93.7 2.7 1.7 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF3683 PF12447.3 KII95219.1 - 0.026 14.3 0.4 0.049 13.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3683) Asp PF00026.18 KII95220.1 - 7.9e-48 163.3 10.4 2.1e-47 161.9 7.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII95220.1 - 3.9e-05 23.6 5.6 0.00034 20.5 2.6 2.9 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KII95220.1 - 0.0014 19.0 4.8 0.057 13.9 0.5 3.0 3 0 0 3 3 3 2 Aspartyl protease Aminotran_1_2 PF00155.16 KII95221.1 - 3.5e-63 213.7 0.0 4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KII95221.1 - 2.8e-06 25.8 0.0 5.2e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KII95221.1 - 9e-05 21.6 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KII95221.1 - 0.00045 19.4 0.0 0.00061 19.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KII95221.1 - 0.0052 15.5 0.0 0.075 11.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Sec63 PF02889.11 KII95222.1 - 3e-85 286.2 0.0 4.6e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KII95222.1 - 1.3e-35 122.3 0.2 4e-28 98.0 0.1 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KII95222.1 - 3e-10 40.2 0.0 4.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KII95222.1 - 2.5e-06 27.6 0.2 0.0073 16.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain Helicase_C PF00271.26 KII95222.1 - 7.3e-06 25.7 0.0 0.00024 20.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KII95222.1 - 0.00057 18.7 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Glyco_transf_4 PF13439.1 KII95222.1 - 0.023 14.4 0.5 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase Family 4 AAA_19 PF13245.1 KII95222.1 - 0.054 13.2 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Sugar_tr PF00083.19 KII95223.1 - 1.6e-109 366.5 22.2 1.8e-109 366.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII95223.1 - 5.9e-24 84.4 40.6 1.4e-19 70.0 8.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KII95223.1 - 0.0038 17.2 7.8 0.25 11.4 0.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) F-box-like PF12937.2 KII95224.1 - 4.8e-05 23.0 0.0 0.00024 20.7 0.0 2.2 1 1 0 1 1 1 1 F-box-like ATE_C PF04377.10 KII95226.1 - 1.1e-43 148.4 1.1 2.3e-43 147.3 0.4 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KII95226.1 - 3.9e-22 77.8 4.5 6.8e-22 77.0 3.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KII95226.1 - 0.043 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S24 PF00717.18 KII95227.1 - 1.7e-10 40.4 0.2 3.2e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KII95227.1 - 0.0031 17.0 0.0 3 7.3 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 WD40 PF00400.27 KII95228.1 - 0.0016 18.2 0.2 0.021 14.6 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF839 PF05787.8 KII95228.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DUF3018 PF11455.3 KII95229.1 - 1.4 8.9 4.6 5.1 7.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3018) EF-hand_1 PF00036.27 KII95231.1 - 2.3e-24 82.7 11.7 3.9e-08 32.0 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KII95231.1 - 3.5e-24 84.7 6.1 7.6e-15 54.7 0.5 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KII95231.1 - 8.8e-20 68.7 6.3 3.6e-06 26.4 0.1 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 KII95231.1 - 6e-13 47.4 11.1 0.00041 19.5 0.7 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KII95231.1 - 1.8e-12 46.6 9.8 4.9e-06 26.0 0.6 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KII95231.1 - 6.6e-07 29.0 6.3 0.065 12.9 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KII95231.1 - 0.00016 21.6 2.9 0.038 14.0 0.2 3.5 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KII95231.1 - 0.0082 16.0 3.1 1.3 9.0 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain S10_plectin PF03501.10 KII95231.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 KII95231.1 - 0.021 14.4 1.6 22 4.7 0.0 4.1 4 0 0 4 4 4 0 EF hand EF-hand_2 PF09068.6 KII95231.1 - 0.047 13.7 0.2 2 8.5 0.0 2.8 3 1 0 3 3 3 0 EF hand DUF106 PF01956.11 KII95232.1 - 2.1e-51 173.7 0.9 3.5e-51 173.0 0.6 1.3 1 1 0 1 1 1 1 Integral membrane protein DUF106 V-SNARE PF05008.10 KII95233.1 - 6.4e-23 80.7 10.1 5.1e-22 77.8 3.6 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KII95233.1 - 2.3e-15 56.3 5.4 2.3e-15 56.3 3.8 2.8 4 0 0 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus RmuC PF02646.11 KII95233.1 - 0.02 13.7 7.8 0.18 10.5 0.3 2.1 2 0 0 2 2 2 0 RmuC family YqjK PF13997.1 KII95233.1 - 0.033 14.3 0.3 0.089 12.9 0.2 1.8 1 0 0 1 1 1 0 YqjK-like protein Sec20 PF03908.8 KII95233.1 - 0.036 13.7 0.5 0.036 13.7 0.3 2.0 2 1 0 2 2 2 0 Sec20 Fusion_gly PF00523.13 KII95233.1 - 0.067 11.2 0.3 0.12 10.3 0.2 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 OppC_N PF12911.2 KII95233.1 - 0.16 11.3 1.3 0.31 10.4 0.9 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Laminin_I PF06008.9 KII95233.1 - 0.36 10.1 11.7 1.2 8.3 2.3 2.4 2 1 0 2 2 2 0 Laminin Domain I Prominin PF05478.6 KII95233.1 - 0.44 8.0 3.1 1.7 6.1 2.1 1.9 1 1 0 1 1 1 0 Prominin TBPIP PF07106.8 KII95233.1 - 0.99 8.9 5.9 2.2 7.7 1.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Flagellin_N PF00669.15 KII95233.1 - 1.5 8.6 8.3 0.86 9.3 1.7 2.6 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF3917 PF13055.1 KII95234.1 - 0.0073 16.5 0.7 0.02 15.1 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3917) BAP PF06639.6 KII95234.1 - 0.09 12.4 0.2 0.35 10.5 0.1 2.1 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) TGS PF02824.16 KII95235.1 - 6.1e-24 83.6 0.1 1.1e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KII95235.1 - 6.1e-18 64.8 0.0 1.6e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KII95235.1 - 4.6e-09 35.7 0.2 1e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KII95235.1 - 0.0054 16.5 0.6 3.7 7.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KII95235.1 - 0.014 14.2 1.1 0.022 13.5 0.2 1.7 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 KII95235.1 - 0.036 14.5 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KII95235.1 - 0.095 12.1 0.1 4.3 6.7 0.1 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Alg6_Alg8 PF03155.10 KII95236.1 - 1.4e-129 433.0 28.2 1.7e-129 432.7 19.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family VMA21 PF09446.5 KII95237.1 - 3e-11 43.0 7.4 3.8e-11 42.7 5.1 1.2 1 0 0 1 1 1 1 VMA21-like domain SbcCD_C PF13558.1 KII95239.1 - 0.021 14.7 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TAF4 PF05236.9 KII95239.1 - 0.065 12.5 0.1 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DPBB_1 PF03330.13 KII95240.1 - 3.3e-07 30.2 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel WD40 PF00400.27 KII95241.1 - 2.2e-73 239.7 18.8 2.3e-09 36.7 0.0 12.6 13 0 0 13 13 13 11 WD domain, G-beta repeat Utp12 PF04003.7 KII95241.1 - 3.2e-19 68.8 0.5 5.3e-19 68.1 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KII95241.1 - 3.8e-08 31.9 4.9 0.0011 17.2 0.0 4.3 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KII95241.1 - 5.4e-05 22.6 0.0 0.077 12.5 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 KII95241.1 - 0.0015 17.4 10.7 0.7 8.5 0.3 6.0 2 2 2 6 6 6 2 Nup133 N terminal like Peptidase_M18 PF02127.10 KII95242.1 - 7.7e-155 515.6 0.0 8.7e-155 515.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KII95242.1 - 0.0016 17.3 0.5 0.26 10.0 0.2 2.5 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase Brix PF04427.13 KII95243.1 - 9.1e-50 168.9 0.9 1.3e-49 168.5 0.6 1.2 1 0 0 1 1 1 1 Brix domain Ribonuc_red_sm PF00268.16 KII95244.1 - 7.5e-119 395.8 1.9 9.3e-119 395.5 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 KII95245.1 - 1.5e-118 394.8 0.2 1.9e-118 394.5 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Aldose_epim PF01263.15 KII95246.1 - 7.1e-58 196.0 0.9 9e-58 195.7 0.6 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Vps52 PF04129.7 KII95248.1 - 3.2e-61 207.4 0.3 1.2e-42 146.0 0.0 2.9 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 KII95248.1 - 5.6e-06 24.8 0.0 0.001 17.3 0.1 2.3 1 1 1 2 2 2 2 Exocyst complex component Sec3 MscS_porin PF12795.2 KII95248.1 - 0.0071 15.6 0.4 0.016 14.5 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Cep57_MT_bd PF06657.8 KII95248.1 - 0.06 13.2 0.5 0.17 11.8 0.4 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 JAB PF01398.16 KII95250.1 - 7e-35 119.2 0.2 1.2e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KII95250.1 - 1.7e-28 99.0 2.8 4e-28 97.8 1.4 2.0 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KII95250.1 - 7.4e-08 31.9 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KII95250.1 - 0.074 12.5 0.6 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.15 KII95251.1 - 2.3e-15 56.2 0.2 3.9e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.20 KII95252.1 - 4e-63 212.9 0.0 7.7e-41 139.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KII95252.1 - 4.7e-28 97.9 0.0 4.7e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KII95252.1 - 9e-13 48.2 0.1 1.6e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KII95252.1 - 7.1e-08 31.7 0.1 6.1e-05 22.1 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KII95252.1 - 0.0031 17.2 1.3 0.006 16.3 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KII95252.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII95252.1 - 0.04 13.2 0.0 0.089 12.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KII95252.1 - 0.042 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.1 KII95252.1 - 0.11 12.8 0.2 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 PAS domain RRS1 PF04939.7 KII95254.1 - 6.9e-59 198.0 6.0 1.1e-58 197.4 4.2 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SAA PF00277.13 KII95254.1 - 0.084 13.2 0.4 0.084 13.2 0.3 2.2 3 0 0 3 3 3 0 Serum amyloid A protein TIP41 PF04176.8 KII95255.1 - 1.1e-51 174.6 0.0 1.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.6 KII95256.1 - 4.9e-38 130.9 4.6 4.9e-28 98.0 0.0 4.1 3 2 0 3 3 3 3 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 KII95256.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KII95256.1 - 0.014 15.4 0.0 0.054 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KII95256.1 - 0.015 14.7 0.1 0.04 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KII95256.1 - 0.062 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KII95256.1 - 0.065 12.6 0.1 0.53 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KII95256.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KII95256.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Dynamin_N PF00350.18 KII95256.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 KII95256.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain FANCI_S1-cap PF14674.1 KII95256.1 - 0.12 12.4 0.8 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 FANCI solenoid 1 cap ABC_tran PF00005.22 KII95256.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 KII95256.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Hep_59 PF07052.6 KII95258.1 - 2e-26 92.3 1.7 2e-26 92.3 1.2 3.1 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Pro-kuma_activ PF09286.6 KII95259.1 - 1.4e-38 132.1 0.1 2.5e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KII95259.1 - 1e-05 24.8 0.2 2.1e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family PCI PF01399.22 KII95260.1 - 3.7e-12 46.4 0.0 1.5e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain Phytochelatin_C PF09328.5 KII95260.1 - 0.044 13.2 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) DUF2009 PF09418.5 KII95261.1 - 2.2e-204 679.4 0.0 2.6e-204 679.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 KII95261.1 - 4.9e-06 26.3 6.7 8.7e-06 25.5 4.6 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF3661 PF12400.3 KII95262.1 - 1.1e-38 132.2 3.6 1.5e-38 131.7 2.5 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF605 PF04652.11 KII95262.1 - 4.7 6.5 22.8 6.1 6.1 15.8 1.1 1 0 0 1 1 1 0 Vta1 like AAA PF00004.24 KII95264.1 - 2.8e-53 179.6 0.0 4.9e-39 133.5 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII95264.1 - 2.3e-10 40.7 0.2 0.00021 21.4 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KII95264.1 - 5.9e-09 36.1 0.4 0.00067 19.6 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.12 KII95264.1 - 2.6e-08 33.3 0.1 1.5e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 KII95264.1 - 5.1e-08 33.7 0.0 0.0018 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 KII95264.1 - 5.4e-08 32.6 0.0 5.6e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KII95264.1 - 1.3e-07 31.7 0.1 4.8e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KII95264.1 - 1.3e-07 31.4 0.5 0.0014 18.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KII95264.1 - 2.5e-07 30.6 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KII95264.1 - 2.8e-07 29.8 0.2 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KII95264.1 - 3e-07 30.8 0.1 0.0035 17.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 KII95264.1 - 4.8e-07 28.8 0.1 0.01 14.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KII95264.1 - 8.5e-07 28.6 3.3 0.0064 16.2 0.1 3.2 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 KII95264.1 - 4.7e-06 25.9 0.2 0.0058 15.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KII95264.1 - 2e-05 24.7 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 KII95264.1 - 3.5e-05 23.6 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KII95264.1 - 4.5e-05 22.9 0.7 0.025 14.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 KII95264.1 - 6.2e-05 22.7 1.7 0.18 11.4 0.0 3.2 3 1 0 3 3 3 2 NACHT domain Zeta_toxin PF06414.7 KII95264.1 - 7.1e-05 21.9 0.3 0.37 9.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.1 KII95264.1 - 0.00013 21.6 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 KII95264.1 - 0.00013 21.1 1.5 0.021 13.9 0.1 2.7 2 1 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 KII95264.1 - 0.00019 20.9 0.1 0.51 9.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.1 KII95264.1 - 0.00025 20.6 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KII95264.1 - 0.00029 20.2 3.6 1.1 8.6 0.0 4.1 2 2 2 4 4 4 1 AAA domain AAA_3 PF07726.6 KII95264.1 - 0.00045 19.8 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KII95264.1 - 0.001 18.0 0.3 0.17 10.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KII95264.1 - 0.0013 18.7 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KII95264.1 - 0.0015 18.8 0.3 0.11 12.7 0.1 2.4 2 0 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 KII95264.1 - 0.0017 17.9 0.2 0.3 10.7 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KII95264.1 - 0.0017 17.9 1.5 1.2 8.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 KII95264.1 - 0.0027 16.6 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KII95264.1 - 0.0062 15.4 0.3 0.59 8.9 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.10 KII95264.1 - 0.0065 16.3 0.1 5.2 6.8 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KII95264.1 - 0.007 16.0 0.4 12 5.4 0.1 3.5 2 2 2 4 4 3 0 Archaeal ATPase PhoH PF02562.11 KII95264.1 - 0.0079 15.4 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein KTI12 PF08433.5 KII95264.1 - 0.0088 15.2 0.1 0.85 8.7 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 T2SE PF00437.15 KII95264.1 - 0.012 14.5 0.2 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Torsin PF06309.6 KII95264.1 - 0.017 14.9 0.1 9.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Torsin KAP_NTPase PF07693.9 KII95264.1 - 0.025 13.6 0.0 5 6.0 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain CPT PF07931.7 KII95264.1 - 0.026 14.1 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.17 KII95264.1 - 0.063 13.1 0.2 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase cobW PF02492.14 KII95264.1 - 0.069 12.5 0.2 11 5.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KII95264.1 - 0.13 11.7 0.0 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 KII95264.1 - 0.15 10.6 0.3 2 6.9 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 KII95264.1 - 0.2 11.3 0.7 9.4 5.9 0.0 2.8 3 0 0 3 3 2 0 NTPase IPP-2 PF04979.9 KII95265.1 - 3.1e-13 50.0 5.6 3.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF2173 PF09941.4 KII95265.1 - 0.071 13.0 0.4 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) THF_DHG_CYH_C PF02882.14 KII95266.1 - 9.3e-16 57.3 0.1 1.9e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KII95266.1 - 1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ORMDL PF04061.9 KII95267.1 - 8.1e-55 184.0 3.5 1.1e-54 183.6 2.4 1.2 1 0 0 1 1 1 1 ORMDL family DUF2404 PF10296.4 KII95269.1 - 3.4e-05 23.8 0.1 0.00088 19.3 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Uds1 PF15456.1 KII95270.1 - 1.9e-34 118.3 11.1 1.9e-34 118.3 7.7 6.0 4 2 2 6 6 6 2 Up-regulated During Septation DUF3584 PF12128.3 KII95270.1 - 4.9 4.3 71.9 0.22 8.7 13.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) SMK-1 PF04802.10 KII95273.1 - 1e-62 211.1 1.9 1e-62 211.1 1.3 2.4 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 TFIIB PF00382.14 KII95274.1 - 1.1e-35 121.2 0.1 1.7e-21 75.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KII95274.1 - 5.4e-14 51.2 1.7 9.1e-14 50.5 1.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_23 PF13384.1 KII95274.1 - 0.0053 16.3 0.1 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 KII95274.1 - 0.012 15.6 0.1 9.9 6.2 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Cyclin_C PF02984.14 KII95274.1 - 0.021 14.7 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain HTH_5 PF01022.15 KII95274.1 - 0.05 13.2 0.1 4.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.1 KII95274.1 - 0.076 12.2 0.0 13 5.0 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Cyclin_N PF00134.18 KII95274.1 - 0.11 12.0 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Abhydrolase_2 PF02230.11 KII95275.1 - 5.6e-57 192.6 0.0 1.8e-56 190.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KII95275.1 - 2.1e-10 40.5 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII95275.1 - 1e-08 35.3 0.1 3.5e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KII95275.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KII95275.1 - 0.069 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA_m1G_MT PF01746.16 KII95276.1 - 5.8e-32 110.7 0.0 1.1e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Pex24p PF06398.6 KII95276.1 - 0.044 12.5 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin NARP1 PF12569.3 KII95276.1 - 0.45 9.2 8.1 0.84 8.3 5.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Methyltransf_23 PF13489.1 KII95277.1 - 5e-12 45.8 0.0 7.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII95277.1 - 7.5e-10 39.1 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII95277.1 - 4.1e-07 29.7 0.0 7.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII95277.1 - 4e-06 27.2 0.0 8.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KII95277.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII95277.1 - 0.0073 16.8 0.0 0.02 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KII95277.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family RrnaAD PF00398.15 KII95277.1 - 0.045 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-C2H2 PF00096.21 KII95278.1 - 0.92 9.9 5.4 3.7 8.0 0.7 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glyco_hydro_7 PF00840.15 KII95279.1 - 0.15 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 RNA_pol_Rpb2_6 PF00562.23 KII95280.1 - 5.6e-112 374.2 0.0 7.5e-112 373.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KII95280.1 - 2.8e-32 111.3 0.0 4.2e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KII95280.1 - 1.3e-26 92.0 0.2 1.8e-25 88.4 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KII95280.1 - 5e-23 80.8 0.0 1.1e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KII95280.1 - 7.8e-22 77.6 0.0 1.4e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KII95280.1 - 8.8e-18 64.3 0.1 3.2e-14 52.9 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KII95280.1 - 0.0094 15.9 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Nucleoporin2 PF04096.9 KII95281.1 - 2.4e-44 150.5 0.0 3.6e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KII95281.1 - 4.9e-15 55.7 323.7 9.3e-06 25.8 44.2 9.6 2 1 4 7 7 7 4 Nucleoporin FG repeat region Ofd1_CTDD PF10637.4 KII95283.1 - 8.3e-81 271.0 0.0 9e-77 257.7 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KII95283.1 - 2e-14 53.8 0.0 1.9e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RRM_6 PF14259.1 KII95284.1 - 5.2e-22 77.6 0.0 9.5e-10 38.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII95284.1 - 3.4e-20 71.4 0.0 5.4e-09 35.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95284.1 - 4.3e-09 36.0 0.0 0.0013 18.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeLo PF14479.1 KII95284.1 - 0.097 12.4 1.1 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation Nucleo_P87 PF07267.6 KII95284.1 - 0.27 9.8 8.6 0.45 9.1 6.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Phage_B PF02304.10 KII95284.1 - 0.68 10.2 4.8 1.8 8.8 3.3 1.7 1 0 0 1 1 1 0 Scaffold protein B Hid1 PF12722.2 KII95284.1 - 6.6 4.2 5.2 8.9 3.8 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Transgly_assoc PF04226.8 KII95285.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.6 3 0 0 3 3 3 0 Transglycosylase associated protein HIG_1_N PF04588.8 KII95288.1 - 0.003 17.2 1.6 0.0067 16.1 1.1 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TerC PF03741.11 KII95288.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein TerC family CLPTM1 PF05602.7 KII95289.1 - 1.9e-141 471.7 0.0 2.4e-141 471.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 KII95289.1 - 0.00062 19.2 1.2 0.0015 18.0 0.3 2.0 2 0 0 2 2 2 1 PQ loop repeat 2TM PF13239.1 KII95289.1 - 0.076 13.0 4.4 0.085 12.9 1.2 2.5 1 1 1 2 2 2 0 2TM domain TraC PF07820.7 KII95290.1 - 0.0018 18.4 3.2 0.13 12.4 0.3 2.6 2 0 0 2 2 2 2 TraC-like protein MAS20 PF02064.10 KII95291.1 - 1.4e-18 66.9 0.4 7.6e-18 64.5 0.1 2.3 2 1 0 2 2 2 1 MAS20 protein import receptor SET PF00856.23 KII95291.1 - 2e-09 37.9 0.0 2.5e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 SET domain SAF PF08666.7 KII95291.1 - 0.0031 17.8 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 2 SAF domain Ecl1 PF12855.2 KII95291.1 - 0.017 14.4 0.9 0.034 13.4 0.6 1.5 1 0 0 1 1 1 0 Life-span regulatory factor 14-3-3 PF00244.15 KII95292.1 - 5e-118 392.3 4.4 5.8e-118 392.1 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 KII95292.1 - 0.027 13.9 2.2 0.99 8.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) PGAP1 PF07819.8 KII95293.1 - 6.8e-53 179.5 0.0 9.3e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KII95293.1 - 1.2e-09 38.0 0.0 3.3e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII95293.1 - 1.1e-05 25.4 1.0 5.2e-05 23.2 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII95293.1 - 0.0061 16.1 0.2 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KII95293.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KII95293.1 - 0.1 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 KII95293.1 - 0.6 9.1 0.0 8.2 5.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) CorA PF01544.13 KII95294.1 - 4.4e-47 160.5 0.4 6.5e-47 159.9 0.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KII95294.1 - 0.025 14.3 0.3 0.056 13.2 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus A_thal_3526 PF09713.5 KII95294.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) DUF3826 PF12875.2 KII95294.1 - 0.18 11.4 0.3 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) adh_short PF00106.20 KII95295.1 - 6.5e-20 71.7 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII95295.1 - 3.2e-09 36.7 0.1 5.2e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KII95295.1 - 4.5e-06 26.7 0.2 7.4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KII95295.1 - 4.5e-05 23.3 0.0 9.9e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII95295.1 - 7.6e-05 22.2 0.3 0.00025 20.5 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KII95295.1 - 0.00076 18.5 0.2 0.0011 18.0 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KII95295.1 - 0.0041 17.2 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Methyltransf_PK PF05891.7 KII95295.1 - 0.0075 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NmrA PF05368.8 KII95295.1 - 0.048 12.9 0.5 0.1 11.8 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family NAD_binding_7 PF13241.1 KII95295.1 - 0.066 13.4 0.1 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 KII95295.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KII95295.1 - 0.09 11.6 0.3 0.22 10.4 0.2 1.6 1 1 0 1 1 1 0 Male sterility protein F-box-like PF12937.2 KII95296.1 - 4.6e-05 23.0 1.1 0.36 10.5 0.1 2.8 3 0 0 3 3 3 2 F-box-like F-box-like_2 PF13013.1 KII95296.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 KII95296.1 - 0.095 12.3 0.2 6.7 6.5 0.1 2.5 2 0 0 2 2 2 0 F-box domain SPX PF03105.14 KII95297.1 - 0.035 13.8 0.8 0.062 13.0 0.6 1.5 1 0 0 1 1 1 0 SPX domain Spc7 PF08317.6 KII95297.1 - 0.33 9.5 10.1 0.6 8.7 7.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KII95297.1 - 0.73 7.6 5.9 1.2 6.8 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KII95297.1 - 1.2 8.7 16.2 1.5 8.3 9.0 2.4 2 0 0 2 2 2 0 IncA protein Mnd1 PF03962.10 KII95297.1 - 2.7 7.6 11.5 1.1 8.8 5.9 1.8 2 0 0 2 2 2 0 Mnd1 family TBPIP PF07106.8 KII95297.1 - 3.5 7.1 8.3 3.2 7.2 4.4 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 KII95297.1 - 4.7 7.2 8.8 4.6 7.2 2.1 2.6 2 0 0 2 2 2 0 FlxA-like protein Amidohydro_2 PF04909.9 KII95298.1 - 1.7e-29 103.2 0.1 2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.23 KII95300.1 - 8.5e-24 83.1 0.0 1.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OPT PF03169.10 KII95301.1 - 2.3e-136 455.7 48.1 2.7e-136 455.5 33.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Integrase_Zn PF02022.14 KII95301.1 - 0.21 11.0 1.2 1.3 8.5 0.0 2.7 4 0 0 4 4 4 0 Integrase Zinc binding domain Arginase PF00491.16 KII95302.1 - 7e-81 271.5 0.2 8.9e-81 271.2 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KII95302.1 - 0.041 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain PLU-1 PF08429.6 KII95303.1 - 8.4e-55 185.9 3.7 1.8e-54 184.8 2.0 2.0 1 1 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 KII95303.1 - 1.1e-40 138.4 1.1 5e-40 136.2 0.2 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 KII95303.1 - 2.3e-16 59.4 0.0 5.8e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KII95303.1 - 9.2e-16 57.2 39.5 1.1e-10 41.0 7.6 4.7 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 KII95303.1 - 4.3e-14 52.3 9.3 1.6e-13 50.4 6.5 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 KII95303.1 - 1.6e-13 49.8 0.5 3.3e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 jmjN domain HTH_31 PF13560.1 KII95303.1 - 0.0017 18.4 0.4 0.0078 16.3 0.3 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain Mis12 PF05859.7 KII95304.1 - 2.1e-20 72.9 0.1 3.1e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Mis12 protein F-box-like PF12937.2 KII95305.1 - 0.00075 19.1 1.2 1 9.1 0.1 2.8 2 0 0 2 2 2 2 F-box-like F-box-like_2 PF13013.1 KII95305.1 - 0.038 13.6 0.1 0.99 9.1 0.0 2.9 3 0 0 3 3 3 0 F-box-like domain RRM_1 PF00076.17 KII95306.1 - 1.3e-09 37.5 0.1 3.5e-06 26.5 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95306.1 - 0.0097 15.7 0.0 0.07 12.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII95306.1 - 0.13 12.2 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) K_channel_TID PF07941.6 KII95308.1 - 0.14 12.4 0.4 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.2 KII95309.1 - 0.00012 21.6 2.1 0.38 10.5 0.1 3.3 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.2 KII95311.1 - 1.9e-05 24.2 0.5 5.1e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII95311.1 - 4e-05 23.1 0.2 0.00028 20.4 0.0 2.1 1 1 1 2 2 2 1 F-box domain Sds3 PF08598.6 KII95312.1 - 0.00043 19.8 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Sds3-like F-box-like PF12937.2 KII95313.1 - 0.00012 21.7 1.8 0.0025 17.4 1.2 2.6 1 1 0 1 1 1 1 F-box-like CDC14 PF08045.6 KII95314.1 - 1.2e-36 126.1 0.0 1.5e-32 112.7 0.0 2.1 2 0 0 2 2 2 2 Cell division control protein 14, SIN component RYDR_ITPR PF01365.16 KII95314.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 RIH domain Aldedh PF00171.17 KII95315.1 - 1.6e-158 527.9 3.5 1.8e-158 527.7 2.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPF0029 PF01205.14 KII95316.1 - 1.2e-24 86.1 0.0 1.7e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KII95316.1 - 6.2e-08 32.5 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain zf-CCCH PF00642.19 KII95317.1 - 0.0021 17.6 2.3 0.0021 17.6 1.6 3.6 2 1 2 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) bZIP_2 PF07716.10 KII95317.1 - 0.032 14.0 1.7 0.077 12.8 1.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF3584 PF12128.3 KII95317.1 - 0.12 9.7 2.2 0.15 9.3 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2570 PF10828.3 KII95317.1 - 0.12 12.0 0.6 0.23 11.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Ax_dynein_light PF10211.4 KII95317.1 - 0.13 12.1 2.7 0.098 12.4 0.7 1.6 2 0 0 2 2 2 0 Axonemal dynein light chain Totivirus_coat PF05518.6 KII95317.1 - 9 3.9 9.1 13 3.4 6.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein zf-CCCH PF00642.19 KII95318.1 - 0.00094 18.8 20.3 0.011 15.3 2.1 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Packaging_FI PF14000.1 KII95318.1 - 0.026 14.7 0.1 0.042 14.0 0.1 1.3 1 0 0 1 1 1 0 DNA packaging protein FI Rho_GDI PF02115.12 KII95319.1 - 9.4e-52 175.3 0.0 1e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UbiA PF01040.13 KII95320.1 - 4.6e-35 121.0 17.4 5.8e-35 120.7 12.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ytp1 PF10355.4 KII95321.1 - 1.2e-74 250.9 6.4 1.6e-55 188.2 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KII95321.1 - 0.0036 16.8 3.8 0.0036 16.8 2.6 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Lamp PF01299.12 KII95322.1 - 0.038 13.1 3.6 0.048 12.8 2.5 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) MFS_1 PF07690.11 KII95323.1 - 1.4e-35 122.7 19.2 1.4e-35 122.7 13.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily cNMP_binding PF00027.24 KII95325.1 - 5.8e-35 118.9 0.0 5.9e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KII95325.1 - 1.9e-08 33.5 0.3 3.7e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Fibrinogen_aC PF12160.3 KII95325.1 - 0.18 11.3 0.4 0.36 10.3 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain ubiquitin PF00240.18 KII95326.1 - 0.00032 20.0 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KII95326.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Glyco_hydro_9 PF00759.14 KII95327.1 - 1.2e-98 330.9 10.5 1.9e-97 326.9 7.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 Mid2 PF04478.7 KII95327.1 - 0.008 15.6 1.0 0.015 14.7 0.7 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KII95327.1 - 0.033 13.4 4.1 0.076 12.3 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAD_binding_1 PF00667.15 KII95328.1 - 3.2e-51 173.8 0.0 4.7e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KII95328.1 - 1.8e-09 38.0 0.0 4.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KII95328.1 - 0.00072 19.4 0.0 0.0031 17.4 0.0 2.0 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KII95328.1 - 0.0089 15.9 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 KII95328.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain GFO_IDH_MocA PF01408.17 KII95329.1 - 3.5e-24 85.6 0.0 1.3e-23 83.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII95329.1 - 2.1e-11 43.6 0.0 3.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KII95329.1 - 0.088 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UPRTase PF14681.1 KII95330.1 - 3.2e-68 229.0 0.0 3.6e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KII95330.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Methyltransf_8 PF05148.10 KII95331.1 - 3e-65 219.9 0.0 5.9e-65 218.9 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KII95331.1 - 8.7e-06 26.1 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII95331.1 - 0.0054 16.4 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII95331.1 - 0.0054 16.3 0.0 3.7 7.1 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KII95331.1 - 0.045 14.1 0.1 0.83 10.0 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KII95331.1 - 0.15 12.5 0.0 0.79 10.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Mucin PF01456.12 KII95331.1 - 0.33 10.7 5.0 0.51 10.0 3.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Mitofilin PF09731.4 KII95331.1 - 2.1 6.8 5.4 2.8 6.5 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_10 PF12846.2 KII95332.1 - 3e-11 43.3 0.0 6.2e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 KII95332.1 - 5.3e-06 26.0 0.0 4.1e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KII95332.1 - 0.00028 21.0 0.0 0.45 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KII95332.1 - 0.0035 17.5 0.0 0.073 13.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KII95332.1 - 0.043 13.2 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KII95332.1 - 0.05 13.5 0.3 7.5 6.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KII95332.1 - 0.061 12.4 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 KII95332.1 - 0.082 12.7 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 KII95332.1 - 0.14 12.0 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 KII95333.1 - 7.6e-22 77.9 0.5 1.4e-21 77.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII95333.1 - 3.8e-12 46.2 0.6 9.5e-12 44.9 0.4 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII95333.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KII95333.1 - 0.00037 20.5 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KII95333.1 - 0.041 13.3 0.0 0.095 12.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 KII95335.1 - 1.3e-67 227.6 0.0 1.8e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95335.1 - 1.5e-30 106.1 0.0 5.9e-29 100.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KII95335.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KII95335.1 - 0.0015 17.5 0.7 1.8 7.4 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pox_ser-thr_kin PF05445.6 KII95335.1 - 0.21 10.3 0.1 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 KII95337.1 - 2.6e-11 42.9 0.4 0.011 15.5 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Peptidase_M28 PF04389.12 KII95340.1 - 3.7e-26 91.9 0.1 5.8e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KII95340.1 - 5.6e-06 25.9 0.0 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.14 KII95341.1 - 1.1e-27 95.9 1.4 1.7e-27 95.3 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KII95341.1 - 2.2e-26 91.0 0.5 3.6e-26 90.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Glyco_hydro_cc PF11790.3 KII95344.1 - 4e-61 206.4 4.0 4.5e-61 206.3 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF4406 PF14359.1 KII95344.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) RRM_1 PF00076.17 KII95345.1 - 7.6e-28 95.9 0.1 1.3e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 KII95345.1 - 1.8e-21 75.4 0.7 4.3e-21 74.2 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_6 PF14259.1 KII95345.1 - 6.4e-21 74.1 0.0 3.1e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95345.1 - 6.3e-11 41.9 0.0 8.6e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KII95345.1 - 2.2e-05 24.1 0.7 0.0001 22.0 0.1 2.4 2 0 0 2 2 2 1 G-patch domain DbpA PF03880.10 KII95345.1 - 0.072 12.7 0.1 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.3 KII95345.1 - 0.091 12.5 1.4 5.9 6.7 0.2 3.4 3 0 0 3 3 3 0 Limkain b1 DNA_RNApol_7kD PF03604.8 KII95347.1 - 1.2e-17 62.9 7.4 1.6e-17 62.6 5.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 KII95347.1 - 0.00046 19.8 0.2 0.00054 19.6 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KII95347.1 - 0.002 17.9 0.8 0.0028 17.4 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ISL3 PF14690.1 KII95347.1 - 0.0027 17.6 2.1 0.014 15.3 0.4 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.6 KII95347.1 - 0.0095 15.5 1.1 0.012 15.2 0.7 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C3HC PF07967.8 KII95347.1 - 0.019 14.7 0.1 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like DUF2296 PF10058.4 KII95347.1 - 0.024 14.3 0.4 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) NinF PF05810.7 KII95347.1 - 0.025 14.3 0.4 0.033 13.9 0.3 1.2 1 0 0 1 1 1 0 NinF protein zinc_ribbon_2 PF13240.1 KII95347.1 - 0.035 13.5 0.7 0.11 12.0 0.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KII95347.1 - 0.036 14.0 3.1 0.086 12.8 2.2 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 KII95347.1 - 0.036 14.3 3.9 0.3 11.3 0.6 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.1 KII95347.1 - 0.039 13.1 0.4 5.6 6.3 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KII95347.1 - 0.064 12.5 2.1 0.89 8.9 0.1 2.1 1 1 0 2 2 2 0 TFIIB zinc-binding zf-trcl PF13451.1 KII95347.1 - 0.086 12.4 6.4 1.6 8.4 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain Ribosomal_L44 PF00935.14 KII95347.1 - 0.18 11.8 4.5 3.2 7.8 1.6 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 GFA PF04828.9 KII95347.1 - 0.19 11.7 1.4 2.5 8.0 0.9 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_5 PF13719.1 KII95347.1 - 0.19 11.3 2.1 1.5 8.4 1.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 KII95347.1 - 0.23 10.5 4.5 3.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Cas_CXXC_CXXC PF09706.5 KII95347.1 - 0.24 11.6 3.9 6.4 7.0 0.4 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) TFIIS_C PF01096.13 KII95347.1 - 0.26 10.9 2.0 3.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.10 KII95347.1 - 0.33 10.5 2.4 3.9 7.1 1.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zinc_ribbon_6 PF14599.1 KII95347.1 - 0.38 10.5 1.8 1.7 8.5 1.2 1.9 1 1 1 2 2 2 0 Zinc-ribbon zf-NADH-PPase PF09297.6 KII95347.1 - 0.45 10.0 3.4 1.6 8.2 2.4 1.8 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF2197 PF09963.4 KII95347.1 - 0.45 10.5 4.4 25 4.9 3.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn_Tnp_IS1595 PF12760.2 KII95347.1 - 0.77 9.6 4.1 2.2 8.1 0.6 1.8 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Orbi_VP7 PF00897.12 KII95349.1 - 0.34 9.7 2.4 0.21 10.5 0.6 1.4 2 0 0 2 2 2 0 Orbivirus inner capsid protein VP7 DUF3425 PF11905.3 KII95350.1 - 1.1e-18 67.4 1.0 2.5e-16 59.8 0.7 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KII95350.1 - 4.2e-09 36.2 6.7 1.5e-08 34.4 4.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KII95350.1 - 0.0021 17.8 8.9 0.0026 17.5 2.3 2.4 2 0 0 2 2 2 1 Basic region leucine zipper Ribosomal_S14 PF00253.16 KII95351.1 - 3.6e-18 64.6 0.3 6e-18 63.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MFS_1 PF07690.11 KII95353.1 - 1.4e-23 83.2 43.5 2.5e-21 75.7 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KII95354.1 - 1.1e-68 231.1 0.0 1.7e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95354.1 - 1.5e-28 99.6 0.0 3.6e-27 95.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII95354.1 - 4.5e-09 35.6 0.0 0.049 12.5 0.0 3.0 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 KII95354.1 - 0.021 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KII95354.1 - 0.025 14.3 0.0 0.92 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.12 KII95355.1 - 7e-20 71.1 0.0 1.3e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding SNARE_assoc PF09335.6 KII95356.1 - 1.6e-12 47.6 7.0 1.6e-12 47.6 4.8 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein PDGLE PF13190.1 KII95356.1 - 0.77 9.4 7.8 13 5.5 0.3 3.3 3 0 0 3 3 3 0 PDGLE domain MARVEL PF01284.18 KII95356.1 - 9.1 6.0 11.5 28 4.5 0.1 2.8 2 1 0 2 2 2 0 Membrane-associating domain DUF2076 PF09849.4 KII95357.1 - 0.016 15.3 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4140 PF13600.1 KII95357.1 - 0.018 15.5 0.1 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PIG-Y PF15159.1 KII95357.1 - 0.02 15.0 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1192 PF06698.6 KII95357.1 - 0.03 14.1 2.2 0.052 13.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DMPK_coil PF08826.5 KII95357.1 - 0.044 13.6 1.8 0.065 13.1 1.3 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like AAA_27 PF13514.1 KII95357.1 - 0.048 11.3 0.0 0.05 11.2 0.0 1.0 1 0 0 1 1 1 0 AAA domain Pox_A_type_inc PF04508.7 KII95357.1 - 0.056 13.2 1.7 0.12 12.1 1.2 1.6 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat DivIC PF04977.10 KII95357.1 - 0.073 12.5 0.2 0.094 12.2 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4391 PF14335.1 KII95357.1 - 0.078 12.3 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Myosin_tail_1 PF01576.14 KII95357.1 - 0.099 10.3 1.0 0.12 10.0 0.7 1.0 1 0 0 1 1 1 0 Myosin tail HR1 PF02185.11 KII95357.1 - 0.1 12.3 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat PEX11 PF05648.9 KII95358.1 - 1.1e-10 41.2 4.9 9.3e-05 21.7 0.1 3.1 2 1 1 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) Spore_coat_CotO PF14153.1 KII95358.1 - 0.019 14.4 0.2 0.031 13.7 0.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Tctex-1 PF03645.8 KII95359.1 - 2.9e-13 49.5 0.0 3.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family MFS_1 PF07690.11 KII95361.1 - 3.7e-32 111.4 26.9 5.3e-32 110.8 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KII95361.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.8 KII95362.1 - 1.7e-80 270.6 0.0 2e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KII95362.1 - 0.11 10.8 0.0 0.18 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Nop PF01798.13 KII95363.1 - 7.2e-41 138.9 0.2 1.1e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 KII95363.1 - 3e-38 131.0 6.2 3e-38 131.0 4.3 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 KII95363.1 - 6.4e-13 48.2 0.1 2.8e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain NifU_N PF01592.11 KII95364.1 - 1.6e-50 170.3 0.1 2.6e-50 169.6 0.0 1.3 1 1 0 1 1 1 1 NifU-like N terminal domain COG6 PF06419.6 KII95365.1 - 1.9e-143 478.8 0.0 2.6e-143 478.3 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Syntaxin-6_N PF09177.6 KII95365.1 - 0.088 13.2 3.0 0.17 12.3 0.9 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TMEM223 PF14640.1 KII95365.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 TMCO5 PF14992.1 KII95365.1 - 1.1 8.2 6.9 1.7 7.7 2.8 2.1 2 0 0 2 2 2 0 TMCO5 family Mannosyl_trans PF05007.8 KII95366.1 - 1.3e-79 267.5 13.9 1.7e-79 267.1 9.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KII95366.1 - 5e-16 58.5 12.9 1.3e-15 57.1 2.1 2.1 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KII95366.1 - 3.7e-08 33.1 8.2 3.7e-08 33.1 5.7 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) TFIID-31kDa PF02291.10 KII95367.1 - 9.5e-30 103.0 0.0 2e-29 102.0 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 KII95367.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KII95367.1 - 0.00049 19.7 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.19 KII95367.1 - 0.0022 18.0 0.1 0.0095 16.0 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BSP_II PF05432.6 KII95367.1 - 1.9 7.7 19.1 2.9 7.1 13.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Prothymosin PF03247.9 KII95367.1 - 8.9 6.5 31.3 8.1 6.6 8.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family WD40 PF00400.27 KII95368.1 - 1.4e-13 50.1 1.0 1.2e-07 31.2 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.7 KII95368.1 - 0.077 12.6 0.1 7.4 6.3 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Mg_trans_NIPA PF05653.9 KII95369.1 - 9.4e-61 205.3 9.9 5.3e-57 193.0 4.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KII95369.1 - 5e-05 23.4 1.2 5e-05 23.4 0.8 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KII95369.1 - 0.00016 21.7 0.2 0.00016 21.7 0.1 3.3 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 KII95369.1 - 0.48 9.2 8.3 0.037 12.8 1.8 1.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) NUFIP1 PF10453.4 KII95370.1 - 0.034 13.6 0.5 0.034 13.6 0.4 1.5 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) C2 PF00168.25 KII95371.1 - 3.6e-12 45.9 0.0 7.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ceramidase PF05875.7 KII95372.1 - 7e-71 238.4 1.7 7.8e-71 238.2 1.2 1.0 1 0 0 1 1 1 1 Ceramidase SID-1_RNA_chan PF13965.1 KII95372.1 - 0.15 10.2 3.1 0.12 10.5 0.5 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1237 PF06824.6 KII95373.1 - 1.3e-139 465.5 0.4 1.5e-139 465.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) F-box-like PF12937.2 KII95374.1 - 1.2e-07 31.3 0.2 4.6e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like Gal4_dimer PF03902.8 KII95374.1 - 0.26 11.2 1.3 0.95 9.4 0.9 2.0 1 1 0 1 1 1 0 Gal4-like dimerisation domain F-box-like PF12937.2 KII95375.1 - 3.8e-08 32.9 0.8 3.8e-08 32.9 0.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII95375.1 - 0.047 13.3 2.6 0.61 9.8 1.8 2.6 1 1 0 1 1 1 0 F-box domain Aconitase PF00330.15 KII95377.1 - 3.5e-179 596.1 0.0 4.2e-179 595.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KII95377.1 - 9.7e-44 148.6 0.0 1.5e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.12 KII95378.1 - 8.6e-19 67.1 9.7 1.5e-18 66.3 6.7 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Tau95 PF09734.4 KII95379.1 - 8.2e-61 206.0 0.1 1.1e-60 205.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit SBP_bac_5 PF00496.17 KII95380.1 - 0.0074 15.1 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF563 PF04577.9 KII95380.1 - 0.051 13.4 0.1 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Sld5 PF05916.6 KII95381.1 - 8.1e-06 26.0 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Pkr1 PF08636.5 KII95382.1 - 4.5e-14 52.2 5.1 5.5e-14 51.9 3.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4191 PF13829.1 KII95382.1 - 0.035 13.2 0.0 0.035 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) LMF1 PF06762.9 KII95382.1 - 0.067 11.9 0.2 0.067 11.9 0.1 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF2244 PF10003.4 KII95382.1 - 0.17 11.2 2.4 0.19 11.0 1.7 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) MARVEL PF01284.18 KII95382.1 - 0.22 11.3 3.8 0.38 10.5 2.7 1.4 1 1 0 1 1 1 0 Membrane-associating domain Pkinase_Tyr PF07714.12 KII95384.1 - 5.7e-32 110.8 0.0 1.2e-31 109.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KII95384.1 - 3.6e-30 105.0 0.0 7.4e-30 103.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain DUF3722 PF12519.3 KII95385.1 - 1e-95 319.8 0.0 1.3e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KII95385.1 - 0.012 14.9 0.0 0.36 10.1 0.0 2.8 3 1 0 3 3 3 0 Eukaryotic porin LSM PF01423.17 KII95387.1 - 4e-17 61.5 0.0 4.6e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain TPMT PF05724.6 KII95388.1 - 1.5e-36 125.8 0.0 1.8e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KII95388.1 - 2.2e-09 37.8 0.0 3.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII95388.1 - 4.5e-07 29.9 0.4 1e-06 28.7 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII95388.1 - 3e-06 27.6 0.0 1.1e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII95388.1 - 8e-06 26.2 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII95388.1 - 1.7e-05 24.4 0.0 8.7e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KII95388.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KII95388.1 - 0.0033 16.6 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB PPR_2 PF13041.1 KII95389.1 - 1.1e-10 41.3 0.1 0.00081 19.3 0.0 4.0 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 KII95389.1 - 7.8e-05 22.3 0.9 1.8 8.7 0.0 4.2 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 KII95389.1 - 0.0076 15.7 0.0 0.076 12.5 0.0 2.6 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 KII95389.1 - 0.039 14.2 4.2 36 4.9 0.1 5.0 6 0 0 6 6 6 0 Pentatricopeptide repeat domain DUF1275 PF06912.6 KII95390.1 - 3.4e-20 72.1 17.0 4.2e-19 68.5 11.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) DUF754 PF05449.6 KII95390.1 - 0.079 12.9 1.8 0.9 9.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF754) Ribosomal_L37ae PF01780.14 KII95390.1 - 0.14 12.0 1.8 0.2 11.5 0.1 2.0 3 0 0 3 3 3 0 Ribosomal L37ae protein family COesterase PF00135.23 KII95394.1 - 2.6e-82 277.2 0.1 2.7e-81 273.9 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII95394.1 - 0.0012 18.5 0.1 0.0027 17.3 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII95394.1 - 0.0086 15.3 0.2 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CoA_transf_3 PF02515.12 KII95395.1 - 5e-49 166.1 0.0 7e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Hce2 PF14856.1 KII95396.1 - 0.058 13.3 0.4 0.25 11.2 0.0 2.0 1 1 1 2 2 2 0 Pathogen effector; putative necrosis-inducing factor RNA_pol_A_bac PF01000.21 KII95397.1 - 8.9e-23 80.5 0.0 1.5e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KII95397.1 - 8.5e-14 50.4 0.0 4.5e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1516 PF07457.6 KII95399.1 - 4.4 7.4 8.2 0.75 9.9 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1516) ATG16 PF08614.6 KII95400.1 - 0.00084 19.2 5.9 0.0018 18.1 4.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BicD PF09730.4 KII95400.1 - 0.0014 17.0 5.8 0.0025 16.2 4.0 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D IncA PF04156.9 KII95400.1 - 0.011 15.3 3.8 0.021 14.4 2.6 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KII95400.1 - 0.011 16.0 6.1 0.077 13.3 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 KII95400.1 - 0.016 15.0 8.0 0.03 14.1 5.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KII95400.1 - 0.019 14.4 11.2 0.12 11.8 0.8 2.7 3 0 0 3 3 3 0 Septum formation initiator Hemerythrin PF01814.18 KII95400.1 - 0.026 14.6 0.7 0.077 13.1 0.5 1.8 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain ADIP PF11559.3 KII95400.1 - 0.026 14.4 5.9 0.05 13.5 4.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 KII95400.1 - 0.032 14.1 7.6 0.086 12.8 0.2 2.8 2 1 1 3 3 2 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 KII95400.1 - 0.034 13.8 5.5 0.058 13.1 3.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4631 PF15450.1 KII95400.1 - 0.041 12.1 3.4 0.064 11.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) DUF3450 PF11932.3 KII95400.1 - 0.068 12.4 3.5 0.11 11.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.4 KII95400.1 - 0.09 12.6 3.6 0.2 11.4 2.5 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain TMF_TATA_bd PF12325.3 KII95400.1 - 0.17 11.5 7.2 0.77 9.4 5.1 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IFP_35_N PF07334.8 KII95400.1 - 0.26 11.2 3.0 12 5.9 0.0 3.1 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ORF11CD3 PF10549.4 KII95400.1 - 0.27 10.9 1.4 4.6 7.0 0.1 2.6 3 0 0 3 3 2 0 ORF11CD3 domain ERM PF00769.14 KII95400.1 - 0.29 10.6 9.5 0.49 9.8 6.6 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF904 PF06005.7 KII95400.1 - 0.33 11.2 7.3 8.5 6.7 5.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Syntaxin-6_N PF09177.6 KII95400.1 - 0.36 11.2 3.1 3.7 8.0 0.5 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Myosin_tail_1 PF01576.14 KII95400.1 - 0.37 8.4 9.9 0.54 7.9 6.9 1.1 1 0 0 1 1 1 0 Myosin tail H-kinase_dim PF02895.9 KII95400.1 - 0.49 10.7 2.3 17 5.8 0.2 2.6 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain V_ATPase_I PF01496.14 KII95400.1 - 0.53 8.0 1.3 0.78 7.5 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 KII95400.1 - 0.55 9.3 8.3 0.11 11.6 1.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KII95400.1 - 0.63 8.6 4.1 1.2 7.6 2.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 KII95400.1 - 0.64 9.8 10.4 3.4 7.5 1.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KII95400.1 - 0.91 8.5 5.7 1.5 7.8 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CorA PF01544.13 KII95400.1 - 1 8.3 3.3 1.7 7.6 2.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Uso1_p115_C PF04871.8 KII95400.1 - 1.1 9.2 7.1 4.7 7.1 4.9 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CALCOCO1 PF07888.6 KII95400.1 - 1.3 7.2 14.6 1 7.5 4.0 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.1 KII95400.1 - 1.3 8.9 6.8 3.2 7.7 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) LLC1 PF14945.1 KII95400.1 - 1.6 9.0 4.9 2.8 8.2 0.3 2.9 2 1 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Seryl_tRNA_N PF02403.17 KII95400.1 - 1.8 8.6 4.9 4.5 7.3 2.7 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NYD-SP28_assoc PF14775.1 KII95400.1 - 2.1 8.0 5.9 1.9 8.2 0.5 2.7 2 1 1 3 3 3 0 Sperm tail C-terminal domain SYCE1 PF15233.1 KII95400.1 - 3 7.7 7.3 16 5.4 5.0 2.0 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 BRE1 PF08647.6 KII95400.1 - 3.6 7.6 7.0 6.4 6.8 4.9 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HALZ PF02183.13 KII95400.1 - 8.5 6.1 7.3 18 5.1 0.3 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Golgin_A5 PF09787.4 KII95401.1 - 0.0017 16.9 0.5 0.0019 16.7 0.3 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 14-3-3 PF00244.15 KII95401.1 - 0.13 11.3 0.3 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 14-3-3 protein G-alpha PF00503.15 KII95402.1 - 2.1e-125 418.4 0.3 2.6e-125 418.1 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KII95402.1 - 4e-15 55.4 0.3 6.3e-10 38.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KII95402.1 - 0.00015 20.9 0.2 0.17 10.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KII95402.1 - 0.01 16.3 0.1 0.9 10.0 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KII95402.1 - 0.049 13.0 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KII95402.1 - 0.057 13.3 0.2 1.8 8.5 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KII95402.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BTB PF00651.26 KII95404.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain HEAT_EZ PF13513.1 KII95405.1 - 2.2e-13 50.2 14.3 1.8e-07 31.4 0.1 7.5 6 2 1 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 KII95405.1 - 1.3e-12 47.8 5.5 1e-06 28.9 0.1 5.2 3 1 4 7 7 7 5 HEAT repeats HEAT PF02985.17 KII95405.1 - 3.9e-12 45.1 14.7 8.1e-06 25.4 0.0 8.5 9 1 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KII95405.1 - 3.4e-09 36.9 0.1 0.00045 20.5 0.0 4.2 3 1 2 5 5 4 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KII95405.1 - 3e-05 22.9 1.9 0.019 13.6 0.1 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 KII95405.1 - 0.0001 22.0 0.5 0.11 12.1 0.0 4.3 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KII95405.1 - 0.00016 21.1 1.3 6.5 6.0 0.0 5.1 4 2 1 5 5 5 2 CLASP N terminal Adaptin_N PF01602.15 KII95405.1 - 0.00047 18.6 0.0 0.0012 17.2 0.0 1.7 2 0 0 2 2 2 1 Adaptin N terminal region DUF4042 PF13251.1 KII95405.1 - 0.017 14.5 0.0 0.94 8.9 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4042) Cnd3 PF12719.2 KII95405.1 - 0.088 11.7 1.0 0.97 8.3 0.0 2.8 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KII95405.1 - 0.11 12.3 0.8 6.3 6.7 0.0 4.0 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat Malate_DH PF12434.3 KII95405.1 - 0.42 10.3 3.9 0.46 10.2 0.4 2.4 2 0 0 2 2 2 0 Malate dehydrogenase enzyme DUF3455 PF11937.3 KII95406.1 - 2.8e-22 79.5 0.2 3.9e-22 79.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3136 PF11334.3 KII95407.1 - 1.1 8.7 6.2 11 5.5 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3136) Effector_1 PF04518.7 KII95410.1 - 0.042 12.8 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Asp_protease_2 PF13650.1 KII95411.1 - 0.0054 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KII95411.1 - 0.0092 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KII95411.1 - 0.098 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2981 PF11200.3 KII95411.1 - 5.5 5.9 7.0 15 4.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) zf-CCHC PF00098.18 KII95412.1 - 0.14 12.1 2.3 0.41 10.6 1.6 1.8 1 1 0 1 1 1 0 Zinc knuckle zf-MYND PF01753.13 KII95415.1 - 6.1e-06 26.0 11.4 1.2e-05 25.0 7.9 1.5 1 0 0 1 1 1 1 MYND finger Cofilin_ADF PF00241.15 KII95415.1 - 0.05 13.4 0.2 1.1 9.1 0.3 2.3 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein HypA PF01155.14 KII95415.1 - 0.078 12.6 1.3 0.17 11.6 0.9 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ecl1 PF12855.2 KII95415.1 - 5.5 6.3 11.8 41 3.5 8.2 2.2 1 1 0 1 1 1 0 Life-span regulatory factor Cpn60_TCP1 PF00118.19 KII95416.1 - 7.3e-132 440.4 1.1 8.4e-132 440.2 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COQ7 PF03232.8 KII95419.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Alpha_L_fucos PF01120.12 KII95420.1 - 3.7e-68 229.9 0.5 4.7e-68 229.6 0.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase RhoGAP PF00620.22 KII95421.1 - 1.3e-42 144.9 0.0 2.7e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 KII95421.1 - 3e-10 40.1 0.0 3.7e-09 36.5 0.0 2.6 3 0 0 3 3 3 1 RasGEF domain PH_9 PF15410.1 KII95421.1 - 2.7e-09 37.2 0.0 2.4e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain RasGEF_N PF00618.15 KII95421.1 - 3e-08 33.7 0.0 2.3e-07 30.8 0.0 2.6 2 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.24 KII95421.1 - 1.4e-05 25.2 0.0 0.0019 18.3 0.0 2.5 2 0 0 2 2 2 1 PH domain PTS_2-RNA PF01885.11 KII95421.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family F-box PF00646.28 KII95422.1 - 6.8e-06 25.5 0.2 3.8e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KII95422.1 - 0.011 15.4 1.7 0.013 15.1 0.2 1.9 2 0 0 2 2 2 0 F-box-like DPBB_1 PF03330.13 KII95423.1 - 0.13 12.2 0.5 0.24 11.4 0.3 1.6 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel NAD_binding_5 PF07994.7 KII95424.1 - 4.3e-106 354.6 0.0 5.1e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KII95424.1 - 8.2e-45 151.2 0.0 1.6e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NIF PF03031.13 KII95425.1 - 3.9e-38 130.6 0.1 5.4e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Peptidase_M15_2 PF05951.8 KII95425.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Homeobox PF00046.24 KII95426.1 - 7.5e-15 54.2 2.7 1e-14 53.8 1.1 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KII95426.1 - 0.006 16.2 0.4 0.015 14.9 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain MFS_1 PF07690.11 KII95429.1 - 1.1e-18 67.1 34.4 1.2e-18 66.9 22.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.8 KII95429.1 - 0.13 12.6 2.5 16 5.9 0.1 3.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF3455 PF11937.3 KII95430.1 - 1.4e-22 80.4 2.3 1.7e-22 80.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CFEM PF05730.6 KII95431.1 - 1.7e-06 27.7 9.9 3.8e-06 26.6 6.8 1.6 1 0 0 1 1 1 1 CFEM domain DUF1517 PF07466.6 KII95431.1 - 3.7 6.4 13.5 0.32 9.9 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) DUF3554 PF12074.3 KII95432.1 - 5.2e-43 147.7 0.2 3.4e-41 141.8 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 KII95432.1 - 5.1e-39 132.4 34.0 9.3e-08 32.2 0.0 14.9 10 4 2 14 14 14 7 HEAT repeats HEAT PF02985.17 KII95432.1 - 1e-34 115.4 24.8 0.028 14.4 0.0 19.4 20 0 0 20 20 19 9 HEAT repeat HEAT_EZ PF13513.1 KII95432.1 - 5.6e-32 109.4 45.5 1e-05 25.8 0.1 19.3 18 2 4 22 22 21 8 HEAT-like repeat CLASP_N PF12348.3 KII95432.1 - 3.6e-11 42.8 0.0 1.1e-05 24.8 0.0 6.7 5 1 2 8 8 8 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KII95432.1 - 4.2e-08 33.4 0.0 2.2 8.6 0.1 6.0 6 0 0 6 6 5 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KII95432.1 - 2.4e-07 29.4 0.0 0.076 11.3 0.0 6.5 7 1 0 8 8 8 1 Adaptin N terminal region Cnd1 PF12717.2 KII95432.1 - 3.8e-06 26.8 0.0 0.93 9.3 0.0 6.7 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KII95432.1 - 0.0037 17.0 0.3 4.8 7.1 0.0 5.5 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KII95432.1 - 0.015 15.2 14.7 0.55 10.2 0.3 6.3 8 0 0 8 8 8 0 HEAT repeat associated with sister chromatid cohesion ParcG PF10274.4 KII95432.1 - 0.29 11.0 0.0 88 2.9 0.0 4.1 3 1 1 4 4 4 0 Parkin co-regulated protein 2OG-FeII_Oxy_3 PF13640.1 KII95433.1 - 1.3e-05 25.6 0.1 2.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KII95433.1 - 0.00068 19.8 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dynamin_N PF00350.18 KII95434.1 - 1.5e-28 99.6 0.0 3e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KII95434.1 - 5.2e-22 77.9 0.0 3.9e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KII95434.1 - 2.3e-11 43.4 0.0 1.9e-10 40.4 0.0 2.6 3 0 0 3 3 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KII95434.1 - 0.0004 20.3 0.0 0.0051 16.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hemerythrin PF01814.18 KII95434.1 - 0.0058 16.7 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain ABC_tran PF00005.22 KII95434.1 - 0.008 16.4 0.1 0.18 12.0 0.0 2.9 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.1 KII95434.1 - 0.011 16.0 0.7 0.38 11.0 0.5 2.5 1 1 0 1 1 1 0 AAA domain Macin PF14865.1 KII95434.1 - 0.035 14.1 0.4 0.074 13.1 0.3 1.5 1 0 0 1 1 1 0 Macin AAA_29 PF13555.1 KII95434.1 - 0.052 13.0 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NIR_SIR_ferr PF03460.12 KII95434.1 - 0.058 13.0 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Miro PF08477.8 KII95434.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KII95434.1 - 0.083 12.3 0.0 18 4.7 0.0 3.1 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain MobB PF03205.9 KII95434.1 - 0.19 11.4 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B COesterase PF00135.23 KII95435.1 - 2.2e-98 330.3 0.0 3.1e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KII95435.1 - 4.5e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII95435.1 - 0.00064 19.0 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF822 PF05687.8 KII95436.1 - 0.012 15.9 0.1 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) 2OG-FeII_Oxy_3 PF13640.1 KII95437.1 - 0.00032 21.1 0.0 0.0008 19.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KII95437.1 - 0.035 14.4 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ceramidase_alk PF04734.8 KII95439.1 - 8.6e-254 843.4 0.1 9.7e-254 843.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase TEA PF01285.13 KII95441.1 - 6e-14 52.0 0.0 6.8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family HycH PF07450.6 KII95443.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Cellulase PF00150.13 KII95444.1 - 0.00071 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pinin_SDK_memA PF04696.8 KII95445.1 - 1e-10 41.3 8.6 1e-10 41.3 6.0 3.2 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region ORC5_C PF14630.1 KII95445.1 - 0.12 11.8 7.4 0.033 13.6 1.0 2.0 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus PRP1_N PF06424.7 KII95445.1 - 1.1 9.5 17.1 4.1 7.7 3.6 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal RGS-like PF09128.6 KII95445.1 - 1.6 8.2 7.5 0.9 9.0 0.6 2.1 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain SRP72 PF08492.7 KII95446.1 - 1.3e-09 38.2 1.3 2.2e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 KII95446.1 - 1.1e-05 25.5 1.1 0.0023 18.0 0.4 2.8 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KII95446.1 - 0.00022 21.5 0.4 0.02 15.2 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII95446.1 - 0.0016 19.0 0.1 1.3 9.7 0.2 2.8 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KII95446.1 - 0.004 17.6 0.0 1.5 9.6 0.0 3.6 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII95446.1 - 0.01 15.4 0.2 7.3 6.3 0.1 2.8 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KII95446.1 - 0.01 15.6 0.8 27 4.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 KII95446.1 - 0.025 13.6 0.8 2.5 7.0 0.3 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KII95446.1 - 0.058 12.5 0.2 0.082 12.0 0.2 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit His_Phos_2 PF00328.17 KII95447.1 - 1.4e-06 27.9 0.0 3.7e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S10 PF00450.17 KII95448.1 - 1.4e-70 238.5 0.3 3.5e-70 237.2 0.2 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase FPN1 PF06963.7 KII95449.1 - 3.6e-113 378.2 14.9 4.6e-113 377.8 10.3 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) adh_short PF00106.20 KII95450.1 - 2.5e-07 30.7 0.1 4.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KII95450.1 - 6.3e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Na_H_Exchanger PF00999.16 KII95451.1 - 3e-63 213.6 46.8 4.1e-63 213.1 32.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DRIM PF07539.7 KII95453.1 - 2.8e-32 111.0 0.0 2.5e-31 107.9 0.0 2.7 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 KII95453.1 - 0.0031 17.4 2.0 43 4.5 0.0 7.0 6 0 0 6 6 6 1 HEAT repeat CLASP_N PF12348.3 KII95453.1 - 0.011 15.1 3.8 0.44 9.8 0.1 4.0 2 1 1 3 3 3 0 CLASP N terminal CTK3 PF12243.3 KII95454.1 - 4.2e-43 146.3 0.0 5.6e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KII95454.1 - 2.2e-16 59.6 11.9 1.4e-15 57.0 8.3 2.2 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Arm PF00514.18 KII95455.1 - 0.081 12.7 0.1 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TMPIT PF07851.8 KII95455.1 - 0.28 10.2 1.5 0.42 9.6 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 KII95455.1 - 0.42 8.3 6.6 0.55 8.0 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KII95455.1 - 0.82 9.2 6.9 4.4 6.8 2.6 2.7 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 KII95455.1 - 1.1 8.0 8.7 1.9 7.3 6.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KII95455.1 - 1.2 8.1 7.8 1.9 7.4 5.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 KII95455.1 - 3.6 7.0 18.5 5.3 6.5 12.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FGGY_C PF02782.11 KII95456.1 - 0.0075 15.9 0.1 1.7 8.2 0.0 3.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_M22 PF00814.20 KII95456.1 - 0.009 15.5 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 2 Glycoprotease family MDMPI_C PF07398.6 KII95456.1 - 0.041 14.4 0.1 10 6.7 0.0 2.9 2 0 0 2 2 2 0 MDMPI C-terminal domain LCCL PF03815.14 KII95456.1 - 0.047 13.6 0.2 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 LCCL domain ATG13 PF10033.4 KII95456.1 - 0.075 12.4 0.3 8.3 5.7 0.1 2.3 2 0 0 2 2 2 0 Autophagy-related protein 13 YjgF_endoribonc PF14588.1 KII95456.1 - 0.09 12.6 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease Thioredoxin_9 PF14595.1 KII95456.1 - 0.12 11.9 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Beta-lactamase PF00144.19 KII95457.1 - 6.6e-32 110.8 2.4 9.8e-21 74.1 1.2 2.4 1 1 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.3 KII95457.1 - 0.0025 17.6 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Rsm22 PF09243.5 KII95457.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RNase_T PF00929.19 KII95459.1 - 3.6e-18 66.3 0.0 5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Mito_carr PF00153.22 KII95460.1 - 1.5e-58 194.5 2.5 3.2e-20 71.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 KII95460.1 - 0.26 11.1 1.8 11 5.8 0.1 2.6 2 0 0 2 2 2 0 Colicin V production protein ARD PF03079.9 KII95462.1 - 1.5e-42 145.2 0.0 1.7e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KII95462.1 - 2.4e-09 36.5 0.0 4.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KII95462.1 - 3.9e-07 29.8 0.0 5.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KII95462.1 - 0.00027 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 KII95462.1 - 0.063 12.7 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_7 PF12973.2 KII95463.1 - 0.00013 21.7 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.6 KII95463.1 - 0.00053 19.4 0.0 0.0009 18.7 0.0 1.4 1 1 0 1 1 1 1 Cupin domain DUF1903 PF08991.5 KII95464.1 - 1.4e-14 53.9 3.4 1.5e-14 53.8 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KII95464.1 - 0.037 13.9 1.8 0.037 13.9 1.2 1.8 2 0 0 2 2 2 0 CHCH domain Herpes_gE PF02480.11 KII95465.1 - 1.6e-05 23.4 0.2 3.1e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KII95465.1 - 0.00014 20.7 0.0 0.00023 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Protocadherin PF08374.6 KII95465.1 - 0.0038 16.8 0.4 0.0066 16.1 0.3 1.5 1 1 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 KII95465.1 - 0.005 17.2 0.5 0.0092 16.3 0.4 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KII95465.1 - 0.011 15.4 1.5 0.011 15.4 1.0 2.3 3 0 0 3 3 3 0 TMEM154 protein family RCR PF12273.3 KII95465.1 - 0.011 16.2 0.0 0.035 14.6 0.0 1.9 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Rifin_STEVOR PF02009.11 KII95465.1 - 0.037 13.6 0.1 0.06 12.9 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Mid2 PF04478.7 KII95465.1 - 0.19 11.1 1.6 0.56 9.5 1.1 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FAM163 PF15069.1 KII95465.1 - 0.98 9.9 7.6 0.2 12.2 1.7 2.6 2 2 0 2 2 2 0 FAM163 family BTB PF00651.26 KII95467.1 - 6.4e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.11 KII95468.1 - 9.2e-32 110.1 22.7 1.5e-31 109.4 15.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 KII95469.1 - 5.9e-33 114.0 0.0 5.6e-18 65.5 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KII95469.1 - 4e-10 40.1 0.0 0.0032 17.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KII95469.1 - 0.00012 21.9 0.0 0.55 10.1 0.0 3.2 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KII95469.1 - 0.00015 21.2 0.7 0.00082 18.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 KII95469.1 - 0.0019 17.4 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KII95469.1 - 0.0091 16.1 0.0 0.25 11.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KII95469.1 - 0.052 12.7 0.0 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 KII95469.1 - 0.064 12.9 0.0 0.79 9.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 KII95469.1 - 0.082 13.3 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KII95469.1 - 0.086 13.1 0.3 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KII95469.1 - 0.22 11.0 0.1 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 KII95469.1 - 0.29 8.4 0.0 0.41 7.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) cobW PF02492.14 KII95469.1 - 0.47 9.8 1.5 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KII95469.1 - 0.57 10.1 3.9 0.98 9.3 0.0 3.0 4 0 0 4 4 4 0 AAA domain Peptidase_M28 PF04389.12 KII95471.1 - 1.9e-29 102.6 0.0 4.9e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 KII95471.1 - 0.0042 15.8 0.0 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Glyco_hydro_16 PF00722.16 KII95473.1 - 1.5e-05 24.3 0.2 2.3e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 BC10 PF06726.7 KII95474.1 - 0.13 12.2 1.2 0.19 11.7 0.2 1.7 1 1 0 1 1 1 0 Bladder cancer-related protein BC10 WD40 PF00400.27 KII95475.1 - 1.1e-29 101.1 12.8 2.9e-07 30.1 0.0 6.6 6 1 1 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KII95475.1 - 8.9e-05 22.2 0.3 0.0069 16.1 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bromodomain PF00439.20 KII95476.1 - 2.4e-20 72.2 0.3 4.4e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KII95476.1 - 4.3e-05 23.1 0.0 8.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated EF-hand_1 PF00036.27 KII95477.1 - 6.3e-24 81.4 0.2 1.4e-06 27.1 0.0 4.7 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KII95477.1 - 8.1e-21 71.9 0.2 1.1e-06 28.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KII95477.1 - 4.6e-20 71.5 0.0 2.2e-10 40.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KII95477.1 - 1.5e-18 65.1 1.1 0.00022 20.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KII95477.1 - 6.9e-16 57.6 2.2 2.9e-08 33.1 0.1 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 KII95477.1 - 0.07 13.0 0.1 5.3 7.0 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain Cation_ATPase_N PF00690.21 KII95477.1 - 0.085 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus WBP-1 PF11669.3 KII95479.1 - 0.12 12.4 1.8 0.27 11.3 1.2 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 TGF_beta_GS PF08515.7 KII95479.1 - 2.5 7.5 7.8 9.6 5.6 4.7 2.3 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Uso1_p115_head PF04869.9 KII95481.1 - 9.1e-50 169.1 0.0 1.9e-48 164.8 0.0 2.8 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KII95481.1 - 1.7e-09 37.7 14.3 2.9e-09 36.9 9.9 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Med21 PF11221.3 KII95481.1 - 0.0002 21.3 1.1 0.00042 20.2 0.8 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Cnd1 PF12717.2 KII95481.1 - 0.013 15.3 0.3 0.18 11.6 0.2 2.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KII95481.1 - 0.048 11.9 0.0 6.1 5.0 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region POX PF07526.6 KII95481.1 - 0.14 12.3 3.1 0.26 11.5 2.1 1.3 1 0 0 1 1 1 0 Associated with HOX Atg14 PF10186.4 KII95481.1 - 7.4 5.4 8.3 12 4.6 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Aminotran_5 PF00266.14 KII95482.1 - 1.5e-31 109.5 0.0 2.9e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KII95482.1 - 0.0063 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PseudoU_synth_2 PF00849.17 KII95483.1 - 1.2e-28 100.0 0.0 1.8e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cwf_Cwc_15 PF04889.7 KII95484.1 - 4.9e-73 245.8 19.1 6.8e-73 245.3 13.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KII95484.1 - 7.4e-05 22.1 21.7 9.4e-05 21.8 15.0 1.1 1 0 0 1 1 1 1 SDA1 SGT1 PF07093.6 KII95484.1 - 0.024 13.0 14.9 0.026 12.8 10.4 1.1 1 0 0 1 1 1 0 SGT1 protein Draxin PF15550.1 KII95484.1 - 0.043 13.4 8.5 0.056 13.0 5.9 1.1 1 0 0 1 1 1 0 Draxin Glyco_tranf_2_4 PF13704.1 KII95484.1 - 0.057 13.7 0.2 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Nop14 PF04147.7 KII95484.1 - 0.085 10.7 24.9 0.1 10.4 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KII95484.1 - 0.24 9.3 19.9 0.29 9.1 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 KII95484.1 - 0.79 7.9 5.5 0.96 7.6 3.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF506 PF04720.7 KII95484.1 - 1.1 8.8 7.1 1.7 8.2 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) SAPS PF04499.10 KII95484.1 - 1.1 7.8 7.1 1.1 7.8 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dsh_C PF12316.3 KII95484.1 - 1.5 8.9 4.5 0.85 9.6 0.7 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal HNF-1_N PF04814.8 KII95484.1 - 2.4 8.2 8.3 3.8 7.5 5.8 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Sporozoite_P67 PF05642.6 KII95484.1 - 3.6 5.3 7.2 5.4 4.7 5.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 KII95484.1 - 4.9 5.5 23.1 6.3 5.1 16.0 1.1 1 0 0 1 1 1 0 Daxx Family U79_P34 PF03064.11 KII95484.1 - 5.4 6.4 21.4 7.5 6.0 14.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Hid1 PF12722.2 KII95484.1 - 5.6 4.5 5.8 6.4 4.3 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 KII95484.1 - 8.8 6.1 16.6 12 5.7 11.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RhoGEF PF00621.15 KII95485.1 - 3.5e-31 108.4 0.0 6.1e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain FAD_binding_4 PF01565.18 KII95486.1 - 1.6e-12 47.1 0.1 2.1e-05 23.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 KII95486.1 - 3.2e-08 33.3 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 KII95486.1 - 0.036 13.6 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.5 KII95486.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CytochromB561_N PF09786.4 KII95486.1 - 2.4 6.5 6.5 3.3 6.0 4.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF535 PF04393.8 KII95487.1 - 0.076 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) E1-E2_ATPase PF00122.15 KII95488.1 - 9.7e-76 253.8 2.1 9.7e-76 253.8 1.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KII95488.1 - 1.3e-38 132.3 1.2 3.4e-38 130.9 0.8 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KII95488.1 - 1.2e-29 104.2 0.0 3.1e-29 102.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KII95488.1 - 1.5e-15 57.8 0.0 4.3e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII95488.1 - 1.5e-15 56.9 0.0 1.1e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KII95488.1 - 7e-10 38.2 0.0 1.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KII95488.1 - 3e-05 23.7 1.9 0.0006 19.4 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 KII95488.1 - 0.0037 16.8 0.1 0.0037 16.8 0.1 3.5 4 0 0 4 4 4 1 Positive regulator of sigma(E), RseC/MucC Abhydrolase_5 PF12695.2 KII95489.1 - 8.6e-18 64.4 0.2 1.9e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII95489.1 - 2.1e-15 57.2 1.8 1.7e-14 54.2 0.2 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KII95489.1 - 8.9e-09 35.2 0.3 1.8e-08 34.2 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KII95489.1 - 4e-08 33.0 0.0 4e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KII95489.1 - 0.00017 20.8 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KII95489.1 - 0.00073 18.8 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.15 KII95489.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF3089 PF11288.3 KII95489.1 - 0.0076 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) DUF818 PF05677.7 KII95489.1 - 0.017 13.9 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF2305 PF10230.4 KII95489.1 - 0.017 14.5 0.0 0.16 11.3 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KII95489.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KII95489.1 - 0.024 14.0 0.1 0.49 9.7 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KII95489.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 KII95489.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S15 PF02129.13 KII95489.1 - 0.056 12.8 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF900 PF05990.7 KII95489.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Saccharop_dh PF03435.13 KII95491.1 - 3.2e-25 88.9 0.3 4.4e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KII95491.1 - 2.6e-09 37.3 0.5 4.4e-09 36.6 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KII95491.1 - 3.9e-07 29.7 0.3 4.3e-06 26.3 0.1 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KII95491.1 - 3.2e-06 27.4 0.0 3.8e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KII95491.1 - 5e-06 25.4 0.0 7.6e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KII95491.1 - 5.4e-06 25.8 0.1 7.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KII95491.1 - 4.1e-05 23.5 1.2 0.00012 22.1 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 KII95491.1 - 0.00028 20.7 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KII95491.1 - 0.00044 19.9 0.3 0.0017 18.0 0.2 2.0 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KII95491.1 - 0.0094 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DXP_reductoisom PF02670.11 KII95491.1 - 0.016 15.7 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase p450 PF00067.17 KII95493.1 - 1e-74 251.7 0.0 3.9e-74 249.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SAM_2 PF07647.12 KII95496.1 - 0.0032 17.2 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Spc7 PF08317.6 KII95496.1 - 0.058 12.0 1.3 0.085 11.4 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KII95496.1 - 1.5 8.3 8.3 0.21 11.1 2.0 2.0 2 0 0 2 2 2 0 IncA protein Ank_2 PF12796.2 KII95498.1 - 0.0057 16.9 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KII95498.1 - 0.0077 16.4 0.2 0.036 14.3 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII95498.1 - 0.015 15.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.25 KII95498.1 - 0.059 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat zf-CHY PF05495.7 KII95499.1 - 1.4e-15 57.1 20.0 1.9e-15 56.7 13.9 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 KII95499.1 - 0.0022 17.5 0.4 0.006 16.1 0.3 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS ArfGap PF01412.13 KII95499.1 - 0.021 14.6 0.9 0.021 14.6 0.6 1.5 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf HypA PF01155.14 KII95499.1 - 0.038 13.6 1.9 0.038 13.6 1.3 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Tmemb_55A PF09788.4 KII95499.1 - 0.071 12.2 5.9 0.083 12.0 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Zn_Tnp_IS1595 PF12760.2 KII95499.1 - 0.1 12.4 12.2 2.2 8.1 5.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KII95499.1 - 0.1 12.5 12.8 0.2 11.6 2.7 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Cys_rich_KTR PF14205.1 KII95499.1 - 0.11 12.0 5.9 0.98 8.9 0.0 2.4 1 1 1 2 2 2 0 Cysteine-rich KTR zf-RING_3 PF14369.1 KII95499.1 - 0.14 12.1 5.8 0.83 9.7 1.9 2.6 1 1 1 2 2 2 0 zinc-finger zinc_ribbon_2 PF13240.1 KII95499.1 - 0.15 11.6 0.2 0.15 11.6 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 KII95499.1 - 0.17 11.3 3.8 0.61 9.6 0.1 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit SIR2 PF02146.12 KII95499.1 - 0.22 11.2 2.7 0.31 10.7 1.8 1.3 1 0 0 1 1 1 0 Sir2 family Zn-ribbon_8 PF09723.5 KII95499.1 - 0.34 10.9 14.6 0.068 13.1 3.1 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 KII95499.1 - 0.36 10.6 12.8 2.6 7.9 8.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon DRP PF06044.7 KII95499.1 - 0.42 9.5 2.6 0.39 9.6 1.2 1.5 1 1 0 1 1 1 0 Dam-replacing family Evr1_Alr PF04777.8 KII95499.1 - 0.69 9.8 10.9 6.1 6.8 7.5 2.5 1 1 0 1 1 1 0 Erv1 / Alr family zf-ribbon_3 PF13248.1 KII95499.1 - 1.3 8.3 5.8 0.81 8.9 1.6 2.4 2 1 0 2 2 2 0 zinc-ribbon domain DUF2197 PF09963.4 KII95499.1 - 1.7 8.6 9.1 3.7 7.5 2.0 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Cytochrome_C7 PF14522.1 KII95499.1 - 5.5 6.7 14.4 11 5.6 10.0 1.5 1 1 0 1 1 1 0 Cytochrome c7 SprT-like PF10263.4 KII95499.1 - 7.1 6.2 8.5 20 4.7 5.9 1.8 1 1 0 1 1 1 0 SprT-like family Bac_rhodopsin PF01036.13 KII95500.1 - 1.4e-39 135.7 20.2 1.7e-39 135.3 14.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Metallophos PF00149.23 KII95502.1 - 5.2e-08 32.5 3.1 8.9e-08 31.7 2.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase N2227 PF07942.7 KII95503.1 - 4.3e-65 219.3 0.0 5.8e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KII95503.1 - 6.9e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KII95503.1 - 0.021 15.2 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KII95503.1 - 0.079 12.9 0.0 0.28 11.2 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain KdpC PF02669.10 KII95505.1 - 0.22 11.1 1.5 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Clat_adaptor_s PF01217.15 KII95507.1 - 1.3e-17 63.7 0.0 2.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FCH PF00611.18 KII95508.1 - 5.1e-20 71.4 1.0 9.4e-20 70.6 0.0 2.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KII95508.1 - 2.1e-10 39.8 0.1 4.3e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KII95508.1 - 1.4e-07 30.9 0.0 3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KII95508.1 - 0.00017 20.9 0.0 0.00039 19.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Myb_DNA-binding PF00249.26 KII95509.1 - 0.049 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRM_6 PF14259.1 KII95511.1 - 9.4e-34 115.2 0.3 7.2e-10 38.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII95511.1 - 1.4e-28 98.3 2.2 5e-09 35.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95511.1 - 1.4e-16 60.0 0.0 0.00049 19.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KII95511.1 - 6.2e-05 22.8 2.2 0.11 12.3 0.1 3.1 3 0 0 3 3 3 2 RNA binding motif NID PF07292.8 KII95511.1 - 0.02 14.9 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Med3 PF11593.3 KII95511.1 - 0.48 9.6 19.6 0.17 11.0 7.9 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 KII95511.1 - 3.1 7.6 12.8 1.1 9.0 4.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.19 KII95512.1 - 9e-104 347.5 21.6 1e-103 347.3 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII95512.1 - 8.2e-23 80.6 60.2 8e-22 77.4 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KII95512.1 - 4e-05 22.0 1.1 8.4e-05 20.9 0.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 KII95513.1 - 2.4e-53 180.7 0.0 2.8e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KII95514.1 - 0.00012 21.6 0.2 0.00092 18.8 0.1 2.3 1 1 0 1 1 1 1 F-box-like IKI3 PF04762.7 KII95516.1 - 2e-243 810.2 0.0 3.3e-241 802.9 0.0 2.1 1 1 0 1 1 1 1 IKI3 family Copine PF07002.11 KII95516.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Copine Apc4_WD40 PF12894.2 KII95516.1 - 0.13 11.7 0.0 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.2 KII95517.1 - 2.3e-05 24.0 0.3 0.00046 19.8 0.2 2.5 1 1 0 1 1 1 1 F-box-like 7tm_6 PF02949.15 KII95517.1 - 0.077 11.8 0.1 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 7tm Odorant receptor BTB PF00651.26 KII95518.1 - 9.1e-05 22.4 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII95519.1 - 3.3e-07 30.2 0.0 6.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII95521.1 - 4.5e-07 29.8 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KII95522.1 - 0.00024 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain polyprenyl_synt PF00348.12 KII95524.1 - 9.1e-39 132.8 0.0 2.4e-25 88.8 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase BTB PF00651.26 KII95527.1 - 0.00069 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF295 PF03478.13 KII95527.1 - 0.0022 17.2 0.0 6.6 6.1 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF295) F-box-like PF12937.2 KII95528.1 - 0.00016 21.3 0.0 0.00063 19.4 0.0 2.1 1 1 0 1 1 1 1 F-box-like DUF2361 PF10153.4 KII95529.1 - 1.3e-28 99.4 10.5 2e-28 98.8 7.3 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) HTH_12 PF08461.5 KII95529.1 - 0.046 13.4 1.4 0.11 12.2 1.0 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain YlbD_coat PF14071.1 KII95529.1 - 0.074 13.1 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative coat protein Adeno_PIX PF03955.9 KII95529.1 - 1.6 9.3 5.6 5.2 7.6 0.2 2.4 1 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) polyprenyl_synt PF00348.12 KII95530.1 - 5e-51 173.0 0.0 2.1e-24 85.7 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase F-box-like PF12937.2 KII95531.1 - 0.016 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KII95534.1 - 5.1e-06 26.1 2.0 3.3e-05 23.5 1.4 2.4 1 1 0 1 1 1 1 F-box-like Ribosomal_S11 PF00411.14 KII95535.1 - 0.00074 19.6 0.4 0.0034 17.5 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S11 F-box-like PF12937.2 KII95537.1 - 0.00048 19.7 1.6 0.00082 19.0 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KII95537.1 - 0.0018 17.8 0.5 0.0061 16.1 0.4 1.9 1 0 0 1 1 1 1 F-box domain CtnDOT_TraJ PF07863.6 KII95537.1 - 1.7 9.1 3.5 1.8 9.0 1.2 1.9 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon E_Pc_C PF06752.7 KII95539.1 - 5.2 6.5 7.8 8.6 5.7 5.4 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus F-box-like PF12937.2 KII95540.1 - 7.7e-05 22.3 2.5 0.00036 20.1 1.8 2.1 1 1 0 1 1 1 1 F-box-like Peptidase_S8 PF00082.17 KII95541.1 - 4.9e-50 170.2 13.9 4.9e-50 170.2 9.6 1.7 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KII95541.1 - 1.1e-14 54.6 0.0 2.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DSBA PF01323.15 KII95542.1 - 5.5e-28 97.8 0.0 6.5e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF1525 PF07511.6 KII95542.1 - 0.0042 17.0 0.1 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1525) Thioredoxin_4 PF13462.1 KII95542.1 - 0.0077 16.2 0.0 0.052 13.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 KII95542.1 - 0.069 12.9 0.0 2.9 7.7 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin domain Retinal PF15449.1 KII95543.1 - 0.069 10.8 15.5 0.089 10.4 10.7 1.1 1 0 0 1 1 1 0 Retinal protein Glyco_hydro_31 PF01055.21 KII95544.1 - 1.6e-146 488.6 4.7 1.6e-146 488.6 3.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KII95544.1 - 8.8e-18 63.9 0.1 7.1e-17 61.0 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Gb3_synth PF04572.7 KII95544.1 - 0.0054 16.4 0.6 0.012 15.2 0.4 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region NAD_Gly3P_dh_N PF01210.18 KII95546.1 - 0.016 14.9 0.0 0.016 14.9 0.0 1.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KII95547.1 - 9.3e-51 172.0 1.2 9.6e-50 168.7 0.9 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KII95547.1 - 3.4e-32 110.7 0.0 6.5e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KII95547.1 - 0.00011 22.0 0.5 0.00051 19.9 0.4 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KII95547.1 - 0.00022 20.9 0.1 0.00041 20.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KII95547.1 - 0.0099 15.0 0.1 0.02 14.0 0.1 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sulfate_transp PF00916.15 KII95548.1 - 5.6e-60 202.7 10.8 5.6e-60 202.7 7.5 2.2 2 1 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KII95548.1 - 1.4e-26 91.9 4.5 1.4e-26 91.9 3.2 3.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KII95548.1 - 1.5e-17 63.0 0.0 3.8e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 KII95548.1 - 2.5e-05 24.2 0.2 8.1e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 STAS domain Myc_target_1 PF15179.1 KII95548.1 - 0.1 12.1 1.1 0.29 10.7 0.7 1.7 1 0 0 1 1 1 0 Myc target protein 1 AA_permease_2 PF13520.1 KII95549.1 - 6.1e-61 206.2 56.1 7.6e-61 205.9 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KII95549.1 - 4.3e-22 78.1 48.7 6.3e-22 77.5 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease Helicase_C PF00271.26 KII95551.1 - 1.4e-18 66.4 0.0 5.7e-18 64.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII95551.1 - 1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KII95551.1 - 4.1e-07 30.0 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_3 PF07859.8 KII95552.1 - 1.6e-23 83.4 0.0 2.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KII95552.1 - 3.5e-11 42.3 0.0 6.8e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KII95552.1 - 0.16 11.2 0.1 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family APH PF01636.18 KII95553.1 - 0.00022 21.0 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KII95553.1 - 0.00043 19.5 0.1 0.00084 18.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Macoilin PF09726.4 KII95553.1 - 0.54 8.4 6.2 0.63 8.2 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 KII95553.1 - 1.4 8.3 11.1 2.1 7.8 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1880 PF08976.6 KII95553.1 - 1.6 8.8 6.3 2.9 8.0 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) DUF566 PF04484.7 KII95553.1 - 2.1 7.7 12.7 2.8 7.3 8.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Herpes_BLLF1 PF05109.8 KII95553.1 - 2.4 5.9 23.5 3.2 5.5 16.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Golgin_A5 PF09787.4 KII95553.1 - 8 4.8 12.6 11 4.3 8.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SNF2_N PF00176.18 KII95554.1 - 6.8e-71 238.4 0.7 1.1e-70 237.8 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII95554.1 - 9e-13 47.9 0.1 8.6e-12 44.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KII95554.1 - 4.5e-06 26.6 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KII95554.1 - 0.00034 20.1 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KII95554.1 - 0.0032 16.3 0.0 2.2 7.0 0.0 2.7 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 KII95556.1 - 1.7e-66 224.0 0.0 2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95556.1 - 5.5e-35 120.6 0.0 7.5e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KII95556.1 - 0.033 13.1 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KII95556.1 - 0.069 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeobox PF00046.24 KII95557.1 - 0.00066 19.2 0.0 0.017 14.7 0.1 2.5 2 0 0 2 2 2 1 Homeobox domain FSH1 PF03959.8 KII95558.1 - 8.9e-53 178.8 0.0 1.1e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KII95558.1 - 8.6e-05 22.3 0.0 0.00019 21.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KII95558.1 - 0.00063 19.6 2.9 0.6 9.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family COX14 PF14880.1 KII95560.1 - 0.014 15.0 4.8 0.026 14.1 3.3 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c assembly ACT_3 PF10000.4 KII95560.1 - 0.035 13.8 0.1 0.081 12.6 0.1 1.6 1 1 1 2 2 2 0 ACT domain Mito_carr PF00153.22 KII95561.1 - 9.9e-68 223.9 5.7 8.4e-23 79.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein eRF1_1 PF03463.10 KII95562.1 - 0.04 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 HEAT_EZ PF13513.1 KII95563.1 - 3.2e-25 87.9 17.5 2e-11 44.0 0.0 11.6 9 4 3 12 12 12 4 HEAT-like repeat HEAT PF02985.17 KII95563.1 - 3.9e-24 82.5 11.5 2.9e-05 23.7 0.0 10.2 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.1 KII95563.1 - 2.2e-20 72.6 0.0 2.1e-05 24.7 0.0 6.7 4 4 3 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.2 KII95563.1 - 3.5e-09 36.9 0.0 0.0096 16.2 0.0 3.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 KII95563.1 - 4.6e-08 32.5 1.3 0.52 10.2 0.0 6.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KII95563.1 - 2e-07 31.0 0.1 0.18 11.6 0.1 5.8 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KII95563.1 - 1.4e-05 24.9 0.2 0.24 11.4 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 KII95563.1 - 4.1e-05 22.1 0.0 0.097 10.9 0.1 3.2 4 0 0 4 4 4 2 Adaptin N terminal region Nipped-B_C PF12830.2 KII95563.1 - 0.24 11.0 0.5 31 4.1 0.0 3.7 4 1 0 4 4 4 0 Sister chromatid cohesion C-terminus Lectin_leg-like PF03388.8 KII95565.1 - 2.3e-64 216.6 0.1 3e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KII95565.1 - 0.00013 21.4 0.0 0.00043 19.7 0.0 1.9 1 1 0 1 1 1 1 Legume lectin domain Pkinase PF00069.20 KII95566.1 - 1e-07 31.4 0.0 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII95566.1 - 5.5e-05 23.0 0.7 9.2e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KII95566.1 - 8.4e-05 21.9 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 KII95566.1 - 8.5e-05 21.7 0.0 0.00059 18.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KII95566.1 - 0.00011 21.7 0.2 0.0002 20.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KII95566.1 - 0.00059 18.9 0.1 0.00099 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KII95566.1 - 0.0018 17.3 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KII95567.1 - 1.9e-05 24.3 0.1 3.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KII95567.1 - 8.5e-05 21.8 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KII95567.1 - 0.0014 17.7 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII95567.1 - 0.0027 17.0 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KII95567.1 - 0.022 14.4 0.2 0.059 13.0 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIF4G PF02854.14 KII95568.1 - 9.2e-44 149.3 0.0 1.2e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain eIF-4B PF06273.6 KII95568.1 - 0.012 14.3 3.6 0.027 13.2 2.5 1.5 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF445 PF04286.7 KII95568.1 - 0.018 14.5 0.4 0.45 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF445) GRP PF07172.6 KII95568.1 - 0.14 12.6 14.5 0.34 11.4 10.0 1.6 1 0 0 1 1 1 0 Glycine rich protein family ER_lumen_recept PF00810.13 KII95569.1 - 1.3e-55 187.9 8.4 1.8e-55 187.5 5.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KII95569.1 - 0.0013 18.2 9.1 0.05 13.1 0.1 3.5 4 0 0 4 4 4 2 PQ loop repeat Pkinase PF00069.20 KII95570.1 - 8.9e-08 31.5 0.1 1.1e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain CCDC155 PF14662.1 KII95571.1 - 0.006 16.1 0.7 0.018 14.6 0.5 1.8 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Med9 PF07544.8 KII95571.1 - 0.021 14.5 0.0 0.086 12.5 0.0 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2580 PF10824.3 KII95571.1 - 0.029 14.6 2.9 0.029 14.6 2.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) Cadherin_2 PF08266.7 KII95572.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like Init_tRNA_PT PF04179.7 KII95573.1 - 3.9e-119 398.4 0.0 5.4e-119 397.9 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase ANTAR PF03861.9 KII95573.1 - 0.18 11.3 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 ANTAR domain Calpain_III PF01067.17 KII95574.1 - 1e-26 93.3 0.3 6.2e-12 45.3 0.0 3.5 3 1 0 3 3 3 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KII95574.1 - 8.2e-08 31.5 0.0 3.7e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.13 KII95574.1 - 3.1e-06 26.9 0.7 5.8e-06 26.1 0.5 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Evr1_Alr PF04777.8 KII95575.1 - 5.4e-29 99.9 1.0 7.6e-29 99.4 0.7 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Kri1_C PF12936.2 KII95576.1 - 4.8e-24 84.1 0.0 4.8e-24 84.1 0.0 5.0 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 KII95576.1 - 1.2e-21 76.9 7.1 1.2e-21 76.9 4.9 5.6 4 2 1 5 5 5 1 KRI1-like family Pantoate_transf PF02548.10 KII95577.1 - 2.7e-99 331.5 0.1 3.4e-99 331.1 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KII95577.1 - 1.5e-09 37.4 0.8 7.8e-09 35.0 0.1 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Saccharop_dh PF03435.13 KII95578.1 - 1.7e-61 208.3 0.0 2.6e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 KII95578.1 - 5.9e-18 64.9 0.0 1.5e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KII95578.1 - 5.5e-11 42.6 0.0 5.3e-10 39.4 0.0 2.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.15 KII95578.1 - 0.0099 15.9 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.2 KII95580.1 - 1.7e-07 31.5 0.0 2.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KII95580.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase Alba PF01918.16 KII95580.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Alba tRNA-synt_2 PF00152.15 KII95581.1 - 1.3e-70 237.7 0.0 2.1e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KII95581.1 - 7.3e-12 44.9 0.1 1.6e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain UPF0270 PF06794.7 KII95581.1 - 0.033 13.9 0.1 5 6.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) DUF4539 PF15072.1 KII95581.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF3328 PF11807.3 KII95582.1 - 3e-48 164.3 0.6 3.7e-48 164.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.19 KII95585.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KII95585.1 - 0.00047 20.2 0.0 0.00094 19.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KII95585.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KII95585.1 - 0.023 14.7 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KII95585.1 - 0.035 13.9 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KII95585.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Claudin_2 PF13903.1 KII95588.1 - 0.24 11.0 6.6 0.27 10.8 4.2 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Transport_MerF PF11431.3 KII95588.1 - 0.58 9.8 4.7 7.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Membrane transport protein MerF TP_methylase PF00590.15 KII95590.1 - 4.4e-17 62.5 0.0 7.3e-17 61.7 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4098 PF13345.1 KII95591.1 - 0.16 11.9 14.3 0.074 13.0 7.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) LSM PF01423.17 KII95592.1 - 7.6e-16 57.4 0.1 1e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain CFEM PF05730.6 KII95594.1 - 0.013 15.2 0.4 0.033 14.0 0.3 1.6 1 0 0 1 1 1 0 CFEM domain Tachylectin PF14517.1 KII95594.1 - 0.027 13.7 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Tachylectin LRR_8 PF13855.1 KII95594.1 - 0.095 12.4 0.1 2 8.2 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat Glyco_hydro_28 PF00295.12 KII95596.1 - 7.5e-60 202.5 11.9 9.5e-60 202.2 8.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 OPT PF03169.10 KII95597.1 - 5.9e-186 619.6 49.9 6.8e-186 619.4 34.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein KdpC PF02669.10 KII95599.1 - 0.16 11.6 4.8 0.22 11.1 0.4 2.1 1 1 1 2 2 2 0 K+-transporting ATPase, c chain zf-MYND PF01753.13 KII95600.1 - 1.3e-09 37.7 7.0 2.6e-09 36.8 4.8 1.5 1 0 0 1 1 1 1 MYND finger Ribosomal_S14 PF00253.16 KII95602.1 - 0.012 14.9 0.2 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e BTB PF00651.26 KII95603.1 - 0.0043 17.0 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RHH_1 PF01402.16 KII95604.1 - 0.053 13.4 0.3 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family BTB PF00651.26 KII95605.1 - 2.5e-08 33.8 0.0 4.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Med13_C PF06333.7 KII95605.1 - 0.31 9.5 1.7 0.38 9.2 1.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal BTB PF00651.26 KII95607.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.4 KII95608.1 - 7.5e-36 123.3 0.0 1.1e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) PGP_phosphatase PF09419.5 KII95610.1 - 3.2e-49 166.5 0.0 4.1e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KII95610.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1168 PF06658.7 KII95611.1 - 1.8 8.0 14.5 0.28 10.7 7.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) ABC_membrane PF00664.18 KII95612.1 - 7.6e-46 156.7 1.5 1e-45 156.3 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KII95612.1 - 4.8e-31 107.8 0.0 1.3e-30 106.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KII95612.1 - 2.5e-05 23.6 0.1 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KII95612.1 - 0.00091 19.2 0.0 0.042 13.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KII95612.1 - 0.035 13.1 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 KII95612.1 - 0.042 13.6 0.4 0.087 12.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 KII95612.1 - 0.064 13.1 0.3 0.28 11.1 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DNA_pol3_a_NI PF14480.1 KII95613.1 - 0.16 11.6 3.1 0.11 12.1 0.9 1.7 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I LigT_PEase PF02834.11 KII95613.1 - 0.22 11.5 1.9 4 7.4 0.1 2.9 3 0 0 3 3 3 0 LigT like Phosphoesterase DUF4140 PF13600.1 KII95613.1 - 2.7 8.4 7.8 7.1 7.1 3.1 2.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 KII95613.1 - 3.6 6.4 8.6 5.5 5.8 5.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Abhydrolase_6 PF12697.2 KII95614.1 - 1.6e-22 80.4 0.4 2.1e-22 80.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KII95614.1 - 1.6e-17 63.1 0.9 7.9e-17 60.8 0.4 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KII95614.1 - 1.6e-17 63.5 0.0 2.7e-17 62.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KII95614.1 - 1.1e-06 27.4 0.3 0.0051 15.3 0.0 2.8 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KII95614.1 - 3.2e-06 26.5 0.1 0.00033 19.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KII95614.1 - 0.00017 20.9 0.1 0.088 12.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KII95614.1 - 0.00054 19.5 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KII95614.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KII95614.1 - 0.0053 16.2 0.1 0.019 14.3 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 KII95614.1 - 0.0082 15.5 0.2 0.016 14.6 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Clathrin_lg_ch PF01086.12 KII95615.1 - 3.8e-39 134.9 2.6 4.6e-39 134.6 1.8 1.2 1 0 0 1 1 1 1 Clathrin light chain Peptidase_C37 PF05416.7 KII95615.1 - 0.075 11.3 1.6 0.099 10.9 1.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase PhoU PF01895.14 KII95615.1 - 0.32 11.4 4.9 0.16 12.4 1.0 2.1 2 0 0 2 2 2 0 PhoU domain Ribosomal_L30_N PF08079.7 KII95615.1 - 0.45 10.5 11.8 0.88 9.6 8.2 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain PTH2 PF01981.11 KII95616.1 - 2.7e-07 30.2 0.0 3.9e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DNA_pol3_chi PF04364.8 KII95616.1 - 0.036 13.8 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC SUR7 PF06687.7 KII95617.1 - 7e-15 55.1 19.3 1.1e-14 54.5 13.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF4231 PF14015.1 KII95617.1 - 0.12 12.3 0.2 0.12 12.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF2263 PF10021.4 KII95619.1 - 6.7e-51 172.1 0.5 2.7e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) DUF218 PF02698.12 KII95619.1 - 0.011 15.2 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 DUF218 domain ubiquitin PF00240.18 KII95620.1 - 3e-08 32.9 0.3 9.4e-08 31.3 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KII95620.1 - 1e-06 28.9 0.1 3.4e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 KII95620.1 - 0.0073 15.9 0.1 0.054 13.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 KII95620.1 - 0.095 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain UN_NPL4 PF11543.3 KII95620.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Aa_trans PF01490.13 KII95622.1 - 1e-27 96.7 26.2 1.7e-27 95.9 18.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UBACT PF02134.16 KII95622.1 - 0.051 13.1 0.3 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein Glyco_hydro_12 PF01670.11 KII95623.1 - 6.1e-36 123.5 4.2 6.1e-36 123.5 2.9 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Gryzun PF07919.7 KII95624.1 - 1.5e-54 185.3 0.0 2.3e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KII95624.1 - 1.5e-49 168.7 1.7 1.2e-48 165.7 0.5 2.4 2 1 0 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 KII95624.1 - 6.3e-05 22.8 0.1 0.037 13.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TRAPPC10 PF12584.3 KII95624.1 - 0.00016 21.1 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_1 PF00515.23 KII95624.1 - 0.006 16.1 0.6 0.066 12.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Gryzun-like PF12742.2 KII95624.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_7 PF13176.1 KII95624.1 - 0.048 13.4 0.8 0.38 10.6 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII95624.1 - 0.049 13.5 4.1 0.063 13.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KII95624.1 - 0.095 12.5 0.0 0.32 10.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII95624.1 - 0.13 12.8 0.3 0.62 10.6 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KII95624.1 - 0.93 9.1 7.9 2.3 7.9 0.0 3.5 4 0 0 4 4 4 0 TPR repeat GST_N_3 PF13417.1 KII95625.1 - 1e-23 83.3 0.0 2.3e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KII95625.1 - 1.3e-15 57.1 0.0 2.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KII95625.1 - 1.3e-08 34.8 0.1 2.3e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KII95625.1 - 8e-08 32.0 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KII95625.1 - 1.3e-05 25.0 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KII95625.1 - 0.00051 20.4 0.0 0.0012 19.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 KII95626.1 - 4.1e-18 66.1 0.1 5.4e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII95626.1 - 5e-08 32.8 0.1 7.5e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII95626.1 - 0.0025 17.3 0.1 0.0065 16.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KII95627.1 - 5.5e-39 133.9 0.1 1.9e-31 109.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KII95627.1 - 1.4e-09 37.1 0.0 2.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KII95627.1 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ATG_C PF09333.6 KII95629.1 - 0.014 15.4 0.0 0.038 14.1 0.0 1.6 2 0 0 2 2 2 0 ATG C terminal domain Hexapep PF00132.19 KII95631.1 - 7.7e-13 47.3 18.0 1.5e-07 30.5 1.4 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KII95631.1 - 1.6e-09 37.1 10.5 1.3e-06 27.8 2.4 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KII95631.1 - 0.00058 18.5 0.1 0.00079 18.0 0.1 1.1 1 0 0 1 1 1 1 L-fucokinase APH PF01636.18 KII95633.1 - 4.2e-36 124.8 0.0 6.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KII95633.1 - 1.4e-05 24.8 0.0 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 KII95633.1 - 0.001 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase HSP70 PF00012.15 KII95634.1 - 1.1e-264 878.9 15.6 1.3e-264 878.7 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KII95634.1 - 5e-14 51.6 6.9 1.2e-12 47.1 0.5 3.2 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 KII95634.1 - 0.0021 17.8 10.0 0.91 9.3 0.1 4.5 4 1 0 4 4 4 2 Cell division protein FtsA FGGY_C PF02782.11 KII95634.1 - 0.031 13.9 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FMN_dh PF01070.13 KII95635.1 - 2.8e-119 398.1 0.1 3.3e-119 397.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KII95635.1 - 2.9e-21 75.0 0.0 6.2e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KII95635.1 - 9.6e-05 21.4 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KII95635.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_mutase PF13714.1 KII95636.1 - 1.3e-47 162.0 3.2 1.8e-47 161.5 2.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KII95636.1 - 3.1e-19 68.6 0.5 5.2e-19 67.8 0.3 1.3 1 0 0 1 1 1 1 Isocitrate lyase family F-box PF00646.28 KII95637.1 - 0.0041 16.7 0.9 0.015 14.9 0.5 2.2 1 1 0 1 1 1 1 F-box domain LCM PF04072.9 KII95638.1 - 1.3e-21 76.9 0.0 2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MIF4G PF02854.14 KII95639.1 - 1.5e-55 187.8 0.1 2.4e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KII95639.1 - 9.8e-17 60.6 0.0 3.3e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 KII95639.1 - 3.7e-05 23.4 0.0 0.00012 21.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain THRAP3_BCLAF1 PF15440.1 KII95639.1 - 0.0012 17.6 38.3 0.0012 17.6 26.6 3.6 4 0 0 4 4 4 1 THRAP3/BCLAF1 family DUF998 PF06197.8 KII95640.1 - 0.025 13.8 4.2 0.054 12.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF3686 PF12458.3 KII95640.1 - 0.087 11.0 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 ATPase involved in DNA repair DUF2407_C PF13373.1 KII95640.1 - 0.15 11.9 0.4 0.31 10.9 0.1 1.7 1 1 1 2 2 2 0 DUF2407 C-terminal domain Arrestin_C PF02752.17 KII95641.1 - 1.4e-16 60.8 0.0 5.3e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KII95641.1 - 6.2e-11 42.3 0.0 6.3e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KII95641.1 - 0.03 13.8 0.0 0.097 12.1 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like Tim17 PF02466.14 KII95642.1 - 2.4e-34 118.1 9.4 3.2e-34 117.7 6.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KII95642.1 - 0.005 16.7 2.6 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF543) TSP9 PF11493.3 KII95642.1 - 0.079 13.5 0.9 16 6.0 0.1 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 TrkH PF02386.11 KII95643.1 - 1.7e-92 309.7 13.4 5.3e-91 304.8 3.8 2.1 2 0 0 2 2 2 2 Cation transport protein Amidohydro_1 PF01979.15 KII95644.1 - 9.5e-19 68.2 0.0 6.3e-14 52.3 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KII95644.1 - 4.8e-18 66.1 0.6 8.7e-09 35.7 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KII95644.1 - 1.1e-08 34.7 0.0 2.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KII95644.1 - 0.00024 20.8 0.0 0.00066 19.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase F-box-like PF12937.2 KII95645.1 - 2.4e-05 23.9 0.2 4.3e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like Transketolase_N PF00456.16 KII95646.1 - 2.4e-120 401.3 0.0 3.3e-120 400.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KII95646.1 - 4.2e-38 130.5 0.0 7.5e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KII95646.1 - 7.2e-08 31.6 0.0 6.6e-06 25.2 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KII95646.1 - 2.2e-06 27.5 0.0 6.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 KII95646.1 - 4.9e-05 22.9 0.1 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KII95646.1 - 0.0051 15.5 0.1 0.0077 14.9 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component F-box-like PF12937.2 KII95647.1 - 7e-07 28.8 3.1 7.1e-07 28.8 0.7 2.2 2 0 0 2 2 2 1 F-box-like ADIP PF11559.3 KII95647.1 - 0.041 13.7 0.8 0.22 11.3 0.5 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NTR2 PF15458.1 KII95647.1 - 0.17 11.0 0.8 0.24 10.5 0.5 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Fungal_trans PF04082.13 KII95648.1 - 6.7e-30 103.8 0.0 1.2e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII95648.1 - 8e-05 22.4 7.4 0.00017 21.3 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTAD PF03704.12 KII95648.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain CsbD PF05532.7 KII95649.1 - 4.3 7.0 9.9 1.7 8.3 3.7 2.5 1 1 1 2 2 2 0 CsbD-like CBM_1 PF00734.13 KII95650.1 - 2.2e-11 43.1 11.8 6.1e-11 41.7 8.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain AXE1 PF05448.7 KII95650.1 - 0.054 11.9 0.1 0.087 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.4 KII95650.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Rer1 PF03248.8 KII95651.1 - 2.8e-71 238.7 0.0 3.4e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 KII95652.1 - 1.6e-25 89.5 30.4 1.6e-25 89.5 21.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.18 KII95653.1 - 2.1e-10 40.2 0.1 3.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KII95653.1 - 8.4e-09 36.0 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Polysacc_lyase PF14099.1 KII95657.1 - 0.0048 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase SprB PF13573.1 KII95657.1 - 0.54 9.8 3.1 0.49 10.0 0.2 2.3 2 0 0 2 2 2 0 SprB repeat AAA_16 PF13191.1 KII95658.1 - 2.7e-05 24.2 0.7 0.00025 21.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KII95658.1 - 0.027 13.9 0.0 0.077 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCCH_2 PF14608.1 KII95659.1 - 4.3e-11 42.3 33.8 0.0058 16.5 5.0 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type UPF0029 PF01205.14 KII95661.1 - 6.1e-22 77.3 0.0 1.5e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF2058 PF09831.4 KII95662.1 - 1.6 8.5 12.0 0.053 13.4 2.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Glyco_hydro_72 PF03198.9 KII95663.1 - 3.4e-110 367.9 0.1 4.2e-110 367.6 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KII95663.1 - 5.7e-20 71.5 0.9 1.9e-19 69.9 0.6 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 KII95663.1 - 0.0031 16.7 0.0 0.086 12.0 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FLILHELTA PF10306.4 KII95664.1 - 3e-09 36.7 0.0 5e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KII95664.1 - 0.01 16.1 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) CTP_transf_2 PF01467.21 KII95666.1 - 2.6e-26 92.5 0.0 3.7e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase bZIP_1 PF00170.16 KII95667.1 - 5.4e-09 35.8 9.9 1.4e-08 34.5 6.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KII95667.1 - 6.5e-07 29.0 11.1 6.5e-07 29.0 7.7 2.1 2 0 0 2 2 2 1 Basic region leucine zipper ATG16 PF08614.6 KII95667.1 - 0.12 12.2 6.0 0.22 11.3 4.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 KII95667.1 - 0.2 11.2 2.7 0.33 10.6 1.8 1.2 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 KII95667.1 - 0.44 10.0 6.6 2 7.9 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Acyl-CoA_dh_N PF02771.11 KII95669.1 - 3.1e-27 95.3 0.0 5.3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KII95669.1 - 5.5e-27 94.7 0.1 8.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII95669.1 - 5.4e-22 77.0 0.3 3.8e-21 74.3 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KII95669.1 - 1.8e-06 28.2 0.2 3.8e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_B_thumb PF14791.1 KII95670.1 - 4e-22 77.6 0.0 7.6e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KII95670.1 - 1.2e-18 67.2 0.1 2.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KII95670.1 - 9.6e-10 37.8 0.0 2.7e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KII95670.1 - 1.8e-09 37.6 0.0 2.2e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KII95670.1 - 2.9e-06 27.3 0.0 2.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 KII95670.1 - 0.00081 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus SUR7 PF06687.7 KII95672.1 - 0.0076 15.8 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KII95672.1 - 0.015 14.9 2.1 0.63 9.7 0.9 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2981 PF11200.3 KII95673.1 - 0.01 14.9 0.9 0.01 14.9 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Sporozoite_P67 PF05642.6 KII95673.1 - 0.26 9.1 4.6 0.28 8.9 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 KII95673.1 - 6.8 6.7 11.4 12 5.8 7.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DEC-1_N PF04625.8 KII95676.1 - 0.31 9.6 2.9 0.31 9.6 2.0 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ADH_N PF08240.7 KII95677.1 - 1e-27 96.0 0.2 1.6e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII95677.1 - 7.9e-16 57.7 0.1 1.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KII95677.1 - 0.0025 18.7 0.0 0.0054 17.6 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KII95677.1 - 0.017 14.2 0.5 0.022 13.8 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KII95677.1 - 0.02 13.9 1.0 0.034 13.2 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII95677.1 - 0.024 14.7 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KII95677.1 - 0.064 12.0 1.1 0.095 11.5 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KII95677.1 - 0.08 12.8 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MtrD PF04207.7 KII95677.1 - 2.5 7.4 5.0 0.59 9.4 0.9 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D Sugar_tr PF00083.19 KII95678.1 - 3.9e-98 328.9 21.8 4.4e-98 328.7 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII95678.1 - 6e-21 74.5 23.6 6e-21 74.5 16.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KII95678.1 - 0.032 12.4 5.4 0.0084 14.3 1.7 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) LRR_6 PF13516.1 KII95679.1 - 3.7 7.8 4.8 12 6.3 0.1 3.9 4 1 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 KII95679.1 - 4.5 7.9 4.9 44 4.9 0.5 4.6 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 KII95680.1 - 0.02 14.6 0.2 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like Steroid_dh PF02544.11 KII95682.1 - 1.3e-27 96.3 0.3 1.3e-27 96.3 0.2 1.9 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KII95682.1 - 3.3e-05 23.3 0.3 5.6e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) p450 PF00067.17 KII95683.1 - 8.3e-71 238.8 0.0 1e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.8 KII95684.1 - 1e-141 472.1 0.0 1.2e-141 471.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DIOX_N PF14226.1 KII95685.1 - 1.1e-26 93.6 0.0 1.6e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KII95685.1 - 2.4e-18 66.2 0.0 7.6e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF221 PF02714.10 KII95686.1 - 2.6e-90 302.5 23.8 4.7e-90 301.7 16.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KII95686.1 - 2.8e-36 124.4 2.8 2.8e-36 124.4 1.9 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KII95686.1 - 4.6e-12 46.2 0.0 9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF809 PF05663.6 KII95686.1 - 0.54 10.1 1.4 7.5 6.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Fungal_trans PF04082.13 KII95687.1 - 4.8e-16 58.4 0.0 7.7e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII95687.1 - 9.8e-05 22.1 6.5 0.00017 21.4 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallothio_6 PF05522.6 KII95687.1 - 0.24 11.7 4.5 0.42 10.9 3.1 1.3 1 0 0 1 1 1 0 Metallothionein Abhydrolase_3 PF07859.8 KII95688.1 - 1.1e-61 208.1 0.0 1.3e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KII95688.1 - 5.4e-10 38.6 0.0 1.5e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KII95688.1 - 7.3e-05 22.0 0.1 0.0022 17.2 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KII95688.1 - 9.6e-05 22.1 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KII95688.1 - 0.0029 16.5 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 KII95688.1 - 0.024 13.2 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 KII95688.1 - 0.087 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase_phd PF10503.4 KII95688.1 - 0.097 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Isochorismatase PF00857.15 KII95689.1 - 3.3e-28 98.7 0.0 3.9e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 KII95690.1 - 8.9e-44 149.6 27.2 8.9e-44 149.6 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII95690.1 - 4.9e-13 48.4 10.0 4.9e-13 48.4 6.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KII95690.1 - 6.4e-07 27.9 4.3 9.7e-07 27.3 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KII95690.1 - 1.7e-05 23.4 6.3 1.7e-05 23.4 4.4 3.9 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 KII95690.1 - 0.0024 16.0 5.5 0.0024 16.0 3.8 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Transp_cyt_pur PF02133.10 KII95691.1 - 6.7e-32 110.6 34.3 1.1e-30 106.6 23.8 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1358 PF07096.6 KII95693.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Fcf1 PF04900.7 KII95694.1 - 4.3e-40 135.9 0.7 4.3e-40 135.9 0.5 1.6 2 0 0 2 2 2 1 Fcf1 Lyase_aromatic PF00221.14 KII95696.1 - 7.9e-160 532.3 5.7 1.2e-159 531.7 4.0 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase F-box-like PF12937.2 KII95697.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like DAO PF01266.19 KII95698.1 - 1.5e-45 155.6 2.6 1.7e-45 155.4 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KII95698.1 - 9.3e-06 25.8 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KII95698.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KII95698.1 - 2e-05 24.3 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KII95698.1 - 0.00019 21.5 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KII95698.1 - 0.00019 20.3 0.2 1.4 7.6 0.1 3.0 2 1 1 3 3 3 2 FAD binding domain Trp_halogenase PF04820.9 KII95698.1 - 0.0008 18.1 0.1 0.0056 15.3 0.1 2.0 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KII95698.1 - 0.00097 19.0 0.2 0.22 11.3 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KII95698.1 - 0.002 17.9 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 ThiF family Amino_oxidase PF01593.19 KII95698.1 - 0.0025 16.9 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KII95698.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII95698.1 - 0.027 13.4 0.0 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KII95698.1 - 0.032 13.0 0.0 4 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KII95698.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.1 KII95698.1 - 0.055 12.3 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KII95698.1 - 0.064 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ELFV_dehydrog PF00208.16 KII95698.1 - 0.078 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Saccharop_dh PF03435.13 KII95698.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 KII95698.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KII95698.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 KII95699.1 - 2.2e-104 347.2 0.0 2.3e-81 272.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KII95699.1 - 8.5e-41 138.5 0.3 1.8e-40 137.5 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KII95699.1 - 2.3e-35 121.0 0.0 1.6e-17 63.5 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KII95699.1 - 1.4e-33 116.2 0.2 2.5e-18 66.4 0.1 3.0 4 0 0 4 4 4 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KII95699.1 - 4.5e-20 71.6 0.0 6.3e-09 35.0 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KII95699.1 - 3.8e-15 55.6 0.0 6.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KII95699.1 - 2e-11 43.6 0.0 6e-06 25.7 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KII95699.1 - 0.00024 20.9 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 KII95699.1 - 0.00089 18.5 0.1 0.43 9.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain KGG PF10685.4 KII95699.1 - 0.067 13.1 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif MGS PF02142.17 KII95699.1 - 0.12 12.3 0.0 1.7 8.6 0.0 2.8 2 0 0 2 2 2 0 MGS-like domain RNase_T PF00929.19 KII95701.1 - 7.1e-29 101.1 0.0 8.3e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease SWIB PF02201.13 KII95702.1 - 9.8e-27 92.4 0.1 1.6e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 KII95702.1 - 0.015 15.1 0.1 0.058 13.1 0.0 2.1 2 1 0 2 2 2 0 DEK C terminal domain Sel1 PF08238.7 KII95703.1 - 5.4e-30 103.1 35.6 7.5e-06 26.4 0.1 10.5 12 1 0 12 12 12 7 Sel1 repeat TPR_11 PF13414.1 KII95703.1 - 0.00017 21.1 18.0 0.0089 15.6 0.7 4.7 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.1 KII95703.1 - 0.0064 17.1 2.1 0.095 13.4 0.1 5.7 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII95703.1 - 0.021 15.2 6.6 4.2 8.0 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 KII95703.1 - 0.031 14.1 1.0 5.7 6.9 0.2 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 KII95703.1 - 0.19 11.7 8.4 5.1 7.0 0.5 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KII95703.1 - 0.2 11.6 0.1 0.2 11.6 0.1 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII95703.1 - 0.43 11.3 8.2 1.1 10.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KII95703.1 - 0.44 10.5 4.2 1 9.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KII95703.1 - 0.67 9.6 12.6 0.54 9.9 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.2 KII95704.1 - 0.00012 22.2 0.0 0.026 14.8 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII95704.1 - 0.002 18.5 2.6 1.3 9.6 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KII95704.1 - 0.0046 17.1 2.3 8.8 6.7 0.0 4.9 4 2 2 6 6 6 1 Ankyrin repeats (many copies) SAP PF02037.22 KII95704.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 SAP domain Ank PF00023.25 KII95704.1 - 0.029 14.1 0.1 30 4.6 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat SnoaL_2 PF12680.2 KII95704.1 - 0.056 13.8 0.9 60 4.1 0.0 3.5 2 1 1 3 3 3 0 SnoaL-like domain Ank_3 PF13606.1 KII95704.1 - 0.066 13.4 0.0 19 5.8 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeat Dimer_Tnp_hAT PF05699.9 KII95704.1 - 2.2 7.9 8.6 16 5.2 0.1 4.6 3 1 2 5 5 5 0 hAT family C-terminal dimerisation region Lactamase_B_3 PF13483.1 KII95705.1 - 1.6e-07 31.1 0.0 4.7e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 KII95705.1 - 0.00052 19.6 0.2 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.2 KII95707.1 - 0.072 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like TauD PF02668.11 KII95708.1 - 1.5e-36 126.4 0.1 2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactamase_B PF00753.22 KII95709.1 - 6.8e-11 42.1 0.1 1.2e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KII95709.1 - 1.9e-05 24.2 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 KII95710.1 - 6.7e-114 380.9 33.9 7.7e-114 380.7 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII95710.1 - 2.3e-24 85.7 43.4 2.3e-24 85.7 30.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 KII95711.1 - 4.3e-42 144.5 0.2 5.9e-42 144.1 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2331 PF10093.4 KII95712.1 - 0.0044 15.8 0.5 0.33 9.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2331) BTV_NS2 PF04514.7 KII95712.1 - 0.017 14.0 1.5 0.023 13.6 1.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2267 PF10025.4 KII95712.1 - 0.085 12.9 1.1 0.2 11.6 0.8 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) 2-Hacid_dh_C PF02826.14 KII95713.1 - 4.5e-50 169.2 0.0 6.8e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII95713.1 - 1.1e-16 60.4 0.0 1.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KII95713.1 - 0.00035 20.4 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_49 PF13896.1 KII95714.1 - 9.8e-40 136.5 2.4 7.3e-31 107.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.1 KII95714.1 - 0.043 14.1 0.2 0.32 11.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 2-Hacid_dh_C PF02826.14 KII95715.1 - 8.9e-49 165.0 0.0 1.9e-48 163.9 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KII95715.1 - 1.4e-17 63.4 0.0 1.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KII95715.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 KII95716.1 - 8.1e-37 126.7 28.6 8.1e-37 126.7 19.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC12 PF06645.8 KII95716.1 - 2 8.2 7.1 1.1 9.1 0.2 3.6 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) LRR_8 PF13855.1 KII95717.1 - 0.022 14.5 2.0 19 5.0 0.0 4.0 3 1 1 4 4 4 0 Leucine rich repeat DPBB_1 PF03330.13 KII95718.1 - 7.6e-06 25.8 0.3 2.7e-05 24.0 0.2 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII95718.1 - 0.048 13.3 0.1 0.097 12.3 0.0 1.5 1 1 0 1 1 1 0 Barwin family Surface_Ag_2 PF01617.12 KII95718.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Surface antigen F-box-like PF12937.2 KII95720.1 - 6.5e-06 25.7 0.6 0.0001 21.9 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KII95721.1 - 6.7e-05 22.5 0.0 0.00026 20.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like Cornichon PF03311.9 KII95722.1 - 3.4e-52 175.9 5.5 3.8e-52 175.7 3.8 1.0 1 0 0 1 1 1 1 Cornichon protein Oxidored_q3 PF00499.15 KII95722.1 - 0.91 9.2 9.6 2.1 8.1 6.7 1.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 RRM_1 PF00076.17 KII95723.1 - 0.0059 16.2 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 KII95723.1 - 0.036 14.0 0.3 0.058 13.4 0.2 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding RRM_5 PF13893.1 KII95723.1 - 0.09 12.6 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII95723.1 - 0.18 11.8 0.0 1.4 8.9 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 KII95724.1 - 0.0042 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KII95724.1 - 0.0065 16.0 0.0 38 4.0 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) DPBB_1 PF03330.13 KII95727.1 - 1.1e-07 31.7 0.2 2.8e-07 30.4 0.2 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII95727.1 - 0.047 13.3 0.1 0.087 12.5 0.1 1.4 1 1 0 1 1 1 0 Barwin family zf-RING_3 PF14369.1 KII95727.1 - 0.15 12.0 0.3 0.31 11.0 0.2 1.5 1 0 0 1 1 1 0 zinc-finger COX2-transmemb PF09125.5 KII95727.1 - 0.34 10.4 1.8 0.57 9.7 1.2 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane F-box-like PF12937.2 KII95729.1 - 2.9e-05 23.7 0.3 0.00013 21.6 0.2 2.2 1 0 0 1 1 1 1 F-box-like CBM_3 PF00942.13 KII95729.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Cellulose binding domain DUF563 PF04577.9 KII95730.1 - 1.3e-20 74.2 0.1 1.3e-20 74.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) MA3 PF02847.12 KII95730.1 - 0.16 11.6 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 MA3 domain zf-C2H2 PF00096.21 KII95731.1 - 2e-26 90.6 69.0 0.0012 19.0 0.3 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KII95731.1 - 2.7e-16 58.5 68.8 0.013 15.8 1.5 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII95731.1 - 3.4e-15 55.4 80.2 1.7e-06 28.0 0.8 12.2 12 1 1 13 13 13 4 Zinc-finger double domain RXT2_N PF08595.6 KII95731.1 - 0.02 14.7 0.4 5.3 6.8 0.1 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-C2H2_6 PF13912.1 KII95731.1 - 5.6 7.0 16.7 19 5.3 0.1 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger IBR PF01485.16 KII95731.1 - 8.7 6.2 30.8 23 4.9 0.1 5.3 2 2 2 4 4 4 0 IBR domain PAM2 PF07145.10 KII95732.1 - 0.0031 16.8 3.9 2.5 7.8 0.0 3.5 3 0 0 3 3 3 2 Ataxin-2 C-terminal region F-box-like PF12937.2 KII95733.1 - 1.6e-05 24.5 0.1 6.1e-05 22.6 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KII95733.1 - 0.56 10.4 3.4 50 4.4 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat MFS_1 PF07690.11 KII95734.1 - 6.6e-31 107.2 70.0 3.2e-26 91.8 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 KII95736.1 - 4.1e-19 68.5 0.0 7.8e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KII95736.1 - 4.7e-19 69.2 0.1 1.3e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KII95736.1 - 1.4e-14 55.0 1.8 3.8e-13 50.3 1.3 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KII95736.1 - 2.6e-13 49.7 0.0 8.6e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KII95736.1 - 0.00098 18.7 0.1 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KII95736.1 - 0.088 13.0 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Choline_kinase PF01633.15 KII95737.1 - 0.00045 19.8 0.1 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KII95737.1 - 0.00068 18.8 0.1 0.00071 18.7 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KII95737.1 - 0.013 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF377 PF04041.8 KII95737.1 - 0.048 12.3 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF377) RIO1 PF01163.17 KII95737.1 - 0.16 11.3 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Trp_halogenase PF04820.9 KII95738.1 - 1.3e-25 89.9 6.2 3.7e-15 55.5 0.1 4.1 4 1 0 4 4 4 3 Tryptophan halogenase FAD_binding_3 PF01494.14 KII95738.1 - 6.2e-10 38.6 0.0 9.4e-09 34.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KII95738.1 - 3e-09 36.2 0.9 1.6e-05 24.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KII95738.1 - 4.6e-06 25.9 1.1 1.1e-05 24.7 0.8 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KII95738.1 - 4.7e-06 25.7 0.6 1.4e-05 24.1 0.4 1.8 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KII95738.1 - 1e-05 25.4 1.0 2.4e-05 24.2 0.2 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KII95738.1 - 1.6e-05 23.6 0.2 2.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KII95738.1 - 3.4e-05 23.8 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KII95738.1 - 3.6e-05 22.8 0.1 5.7e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KII95738.1 - 0.0012 18.0 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KII95738.1 - 0.0012 19.1 0.2 0.027 14.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KII95738.1 - 0.0039 16.1 1.2 0.0082 15.0 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KII95738.1 - 0.024 14.6 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KII95738.1 - 0.06 13.1 0.4 0.17 11.7 0.3 1.8 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 KII95738.1 - 0.087 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KII95738.1 - 0.088 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase G-patch PF01585.18 KII95740.1 - 1.1e-07 31.5 1.7 2.5e-07 30.3 0.2 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KII95740.1 - 0.00012 21.8 0.5 0.00012 21.8 0.4 4.2 5 1 0 5 5 5 1 DExH-box splicing factor binding site DJ-1_PfpI PF01965.19 KII95741.1 - 6.7e-08 32.1 0.1 2e-06 27.3 0.1 2.8 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KII95741.1 - 0.0019 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase PB1 PF00564.19 KII95742.1 - 1.7e-16 59.6 0.0 4.6e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 PB1 domain TPR_11 PF13414.1 KII95742.1 - 2.5e-12 46.2 18.0 1.2e-07 31.2 1.0 3.7 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 KII95742.1 - 1.5e-10 40.2 12.5 0.00028 20.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KII95742.1 - 1.2e-08 34.2 15.7 0.029 14.2 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KII95742.1 - 1.6e-06 27.9 7.0 0.00011 22.0 1.5 3.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KII95742.1 - 1.8e-06 27.3 9.0 0.00085 18.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KII95742.1 - 0.018 14.8 11.0 0.022 14.5 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KII95742.1 - 0.097 12.9 2.4 4 7.8 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KII95742.1 - 0.28 11.3 3.1 0.74 9.9 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KII95742.1 - 0.44 10.9 4.0 78 3.7 2.8 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KII95742.1 - 1.9 9.2 14.4 2.8 8.7 2.2 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII95742.1 - 2.5 8.7 7.7 1.2e+02 3.5 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII95742.1 - 5.4 7.9 12.1 36 5.3 0.1 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KII95742.1 - 8.9 6.3 9.2 4.8 7.2 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat IGPS PF00218.16 KII95743.1 - 1e-94 316.3 0.0 2e-94 315.4 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KII95743.1 - 1.2e-54 184.8 0.0 2e-51 174.3 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KII95743.1 - 1.5e-47 161.5 0.0 2.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KII95743.1 - 4.2e-07 29.6 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KII95743.1 - 0.0013 18.3 0.3 0.056 12.9 0.0 2.8 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KII95743.1 - 0.072 12.3 0.1 0.22 10.7 0.1 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein FMN_dh PF01070.13 KII95743.1 - 0.32 9.7 4.7 0.33 9.7 1.3 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pkinase PF00069.20 KII95744.1 - 6.3e-68 228.7 0.0 7.8e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95744.1 - 4e-29 101.4 0.0 5.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KII95744.1 - 0.014 15.1 0.2 0.044 13.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KII95744.1 - 0.041 12.8 0.0 0.094 11.6 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KII95744.1 - 0.053 12.5 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 KII95745.1 - 6.3e-55 185.9 0.0 7.6e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PH PF00169.24 KII95746.1 - 7.1e-06 26.1 0.0 4.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 PH domain BRCT PF00533.21 KII95747.1 - 0.041 14.0 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 KII95748.1 - 6.4e-16 58.2 0.0 8.5e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KII95748.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KII95748.1 - 1.2e-06 27.8 0.0 1.6e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KII95748.1 - 4.4e-06 25.8 0.1 6.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KII95748.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KII95748.1 - 0.00015 20.8 0.0 0.0002 20.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KII95748.1 - 0.038 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 KII95748.1 - 0.072 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 XPG_I_2 PF12813.2 KII95750.1 - 0.0002 20.9 0.0 0.00073 19.1 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 KII95750.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain TAF1D PF15333.1 KII95750.1 - 2 8.1 3.9 6.2 6.5 0.5 2.5 1 1 1 2 2 2 0 TATA box-binding protein-associated factor 1D DUF1144 PF06610.8 KII95751.1 - 0.046 13.4 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1144) PSRT PF07636.6 KII95751.1 - 4.5 6.8 8.0 0.43 10.0 2.0 2.0 2 0 0 2 2 2 0 PSRT NAD_kinase PF01513.16 KII95752.1 - 3.7e-57 193.2 0.0 4.8e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Pkinase PF00069.20 KII95753.1 - 0.00011 21.3 0.1 0.0026 16.9 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95753.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Hemerythrin PF01814.18 KII95761.1 - 1.4e-10 41.4 0.4 1.9e-10 40.9 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_RpbA PF10789.4 KII95761.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA 3Beta_HSD PF01073.14 KII95762.1 - 2.1e-07 29.9 0.0 3.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KII95762.1 - 2.5e-07 30.4 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KII95762.1 - 0.00053 18.9 0.0 0.0046 15.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KII95762.1 - 0.00065 19.7 0.3 0.015 15.2 0.1 2.6 2 1 0 2 2 2 1 NADH(P)-binding AMP-binding PF00501.23 KII95763.1 - 3.7e-90 302.2 0.1 4.8e-90 301.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KII95763.1 - 1.5e-09 38.6 0.9 1.5e-09 38.6 0.6 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ndc1_Nup PF09531.5 KII95765.1 - 0.2 10.0 3.9 0.14 10.5 1.6 1.3 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AA_permease PF00324.16 KII95767.1 - 7.8e-135 449.8 40.9 9.3e-135 449.6 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KII95767.1 - 1.2e-39 136.0 50.9 2.1e-39 135.2 34.7 1.6 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 KII95769.1 - 1.1e-16 61.4 0.0 1.6e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII95769.1 - 2.7e-08 33.6 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII95769.1 - 0.0072 15.9 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold GIT_SHD PF08518.6 KII95770.1 - 4.8e-25 86.5 4.6 1.8e-13 49.5 1.5 3.0 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Gasdermin PF04598.7 KII95770.1 - 0.098 11.3 6.1 0.18 10.5 2.3 2.2 2 0 0 2 2 2 0 Gasdermin family Tropomyosin PF00261.15 KII95770.1 - 1.5 7.8 33.7 0.0051 15.9 16.3 2.0 3 0 0 3 3 3 0 Tropomyosin Syntaxin PF00804.20 KII95770.1 - 8.6 6.5 13.8 0.22 11.6 0.8 3.8 4 0 0 4 4 4 0 Syntaxin AAA PF00004.24 KII95771.1 - 1.2e-31 109.6 0.0 2.3e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KII95771.1 - 4.3e-09 36.6 0.1 3.3e-08 33.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KII95771.1 - 2.4e-07 31.5 0.0 7e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII95771.1 - 1.3e-06 28.5 1.8 4.7e-06 26.7 0.3 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KII95771.1 - 7.4e-06 26.2 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KII95771.1 - 1.7e-05 24.6 0.1 0.0021 17.7 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 KII95771.1 - 1.9e-05 24.5 0.1 7.5e-05 22.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KII95771.1 - 3.1e-05 23.8 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KII95771.1 - 3.5e-05 22.9 0.1 0.015 14.2 0.0 2.7 2 1 1 3 3 3 1 KAP family P-loop domain AAA_2 PF07724.9 KII95771.1 - 4.3e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KII95771.1 - 6.4e-05 22.4 0.3 0.1 12.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KII95771.1 - 7.4e-05 22.4 0.0 0.0013 18.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 KII95771.1 - 0.0002 20.3 0.0 0.035 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 KII95771.1 - 0.00039 20.0 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KII95771.1 - 0.00056 18.7 0.0 0.00085 18.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Viral_helicase1 PF01443.13 KII95771.1 - 0.00068 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KII95771.1 - 0.00089 18.9 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KII95771.1 - 0.0015 18.4 0.0 0.0049 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KII95771.1 - 0.0027 17.4 0.1 0.011 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KII95771.1 - 0.0029 17.2 0.0 0.0072 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KII95771.1 - 0.003 17.0 0.0 0.0078 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 KII95771.1 - 0.003 17.2 0.2 0.0085 15.7 0.0 2.0 2 1 0 2 2 1 1 NACHT domain RNA_helicase PF00910.17 KII95771.1 - 0.0037 17.4 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.7 KII95771.1 - 0.0042 16.1 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 KII95771.1 - 0.015 14.9 0.0 0.065 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KII95771.1 - 0.016 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 KII95771.1 - 0.025 14.9 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KII95771.1 - 0.026 14.1 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KII95771.1 - 0.027 13.5 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KII95771.1 - 0.041 14.1 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 KII95771.1 - 0.062 12.4 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KII95771.1 - 0.066 11.8 0.0 0.45 9.1 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 KII95771.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 KII95771.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 KII95771.1 - 0.11 11.7 0.0 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein KTI12 PF08433.5 KII95771.1 - 0.12 11.5 0.0 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PduV-EutP PF10662.4 KII95771.1 - 0.14 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CLASP_N PF12348.3 KII95772.1 - 6.9e-76 254.5 0.2 5.5e-69 231.9 0.0 3.7 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 KII95772.1 - 2.8e-08 33.1 5.0 0.13 12.4 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KII95772.1 - 5.6e-07 29.8 3.7 0.075 13.5 0.0 4.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 KII95772.1 - 1.1e-05 25.5 8.6 0.2 11.9 0.0 5.1 5 0 0 5 5 5 3 HEAT repeats Arm PF00514.18 KII95772.1 - 0.071 12.9 3.6 52 3.8 0.1 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Rhomboid PF01694.17 KII95773.1 - 1.7e-20 73.5 6.1 3.6e-20 72.4 4.2 1.5 1 0 0 1 1 1 1 Rhomboid family Rav1p_C PF12234.3 KII95773.1 - 0.23 9.5 0.0 0.32 9.1 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal Sedlin_N PF04628.8 KII95774.1 - 5.7e-41 139.4 0.0 7.4e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KII95774.1 - 2.8e-09 36.8 0.0 3.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family CtIP_N PF10482.4 KII95775.1 - 0.83 9.4 3.3 1.3 8.7 2.3 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Actin PF00022.14 KII95776.1 - 1.1e-112 376.4 0.0 1.2e-112 376.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KII95776.1 - 4.9e-07 28.6 0.1 0.017 13.7 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein BOP1NT PF08145.7 KII95777.1 - 7.9e-98 327.3 7.5 1e-97 326.9 5.2 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KII95777.1 - 9e-20 69.7 18.5 1.4e-07 31.1 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat F-box-like PF12937.2 KII95779.1 - 3.9e-08 32.8 1.1 1e-07 31.5 0.8 1.8 1 0 0 1 1 1 1 F-box-like Rdx PF10262.4 KII95780.1 - 3.8e-18 65.2 0.0 4.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Rdx family DUF2423 PF10338.4 KII95781.1 - 3.2e-12 46.1 7.2 7e-12 45.1 5.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) LSM PF01423.17 KII95782.1 - 1.2e-19 69.5 0.0 1.4e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KII95782.1 - 0.011 15.6 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.18 KII95783.1 - 3.2e-19 68.7 0.4 5.5e-19 67.9 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Terpene_synth PF01397.16 KII95783.1 - 0.0063 15.9 0.6 0.0077 15.6 0.4 1.2 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Histone PF00125.19 KII95783.1 - 0.046 13.8 0.1 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KII95783.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated 4HB_MCP_1 PF12729.2 KII95783.1 - 0.39 10.0 2.7 0.46 9.8 1.4 1.5 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction PfkB PF00294.19 KII95784.1 - 7.3e-15 54.8 0.0 9.2e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KII95784.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase ACPS PF01648.15 KII95785.1 - 9.5e-13 47.9 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily F-box-like PF12937.2 KII95786.1 - 0.0097 15.6 0.2 0.02 14.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII95786.1 - 0.14 11.8 1.8 2.7 7.7 0.1 2.7 3 0 0 3 3 3 0 F-box domain tRNA-synt_2 PF00152.15 KII95787.1 - 3.5e-105 351.4 0.0 8.7e-105 350.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KII95787.1 - 1.9e-06 27.6 0.0 5.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KII95787.1 - 0.012 15.2 0.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) IMD PF08397.6 KII95788.1 - 5.6e-05 22.5 2.3 7.9e-05 22.0 1.6 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain ARD PF03079.9 KII95788.1 - 0.00088 19.2 1.3 0.0015 18.5 0.9 1.3 1 0 0 1 1 1 1 ARD/ARD' family BAR PF03114.13 KII95788.1 - 0.0043 16.5 1.9 0.0087 15.5 1.3 1.5 1 1 0 1 1 1 1 BAR domain DUF3829 PF12889.2 KII95788.1 - 0.17 11.0 3.7 0.13 11.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Fucose_iso_N2 PF07882.7 KII95788.1 - 0.31 10.6 1.7 0.5 9.9 1.2 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Ribosomal_L19 PF01245.15 KII95789.1 - 1.2e-16 60.4 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.17 KII95790.1 - 1.6e-17 62.8 0.0 2.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII95790.1 - 1.6e-15 56.8 0.0 3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95790.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KII95791.1 - 3.5e-37 127.7 0.0 5.6e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII95791.1 - 6.2e-10 38.8 12.3 1.1e-09 37.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KII95791.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Rep_fac-A_C PF08646.5 KII95791.1 - 4.1 7.0 5.4 7.4 6.2 3.8 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Acyl-CoA_dh_1 PF00441.19 KII95792.1 - 1.7e-27 96.3 0.2 2.6e-27 95.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII95792.1 - 5.6e-15 54.6 0.0 1.4e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KII95792.1 - 1.9e-12 47.6 0.3 1.9e-12 47.6 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KII95792.1 - 3.4e-10 40.4 0.1 9.3e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Suc_Fer-like PF06999.7 KII95793.1 - 3.2e-39 135.3 0.0 2.7e-38 132.2 0.0 2.2 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Suc_Fer-like PF06999.7 KII95795.1 - 2.6e-36 125.7 0.0 4.4e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.20 KII95796.1 - 5.4e-69 232.2 0.0 7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KII95796.1 - 3.1e-29 101.8 0.0 4.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KII95796.1 - 1.4e-15 57.4 1.1 1.4e-15 57.4 0.7 2.4 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KII95796.1 - 4.4e-09 35.7 0.0 3.3e-08 32.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like C2 PF00168.25 KII95796.1 - 1.7e-05 24.5 0.1 0.093 12.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 KII95796.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KII95796.1 - 0.044 12.8 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Diphthamide_syn PF01866.12 KII95800.1 - 3.6e-88 295.7 0.0 1.4e-31 109.9 0.2 3.9 3 1 0 3 3 3 3 Putative diphthamide synthesis protein Patched PF02460.13 KII95801.1 - 1.7e-66 224.7 12.6 5.6e-38 130.4 0.1 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 KII95801.1 - 6.3e-44 149.1 13.8 5.2e-23 81.1 0.1 3.6 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KII95801.1 - 1.6e-05 22.5 9.8 2.4e-05 22.0 4.8 2.0 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.9 KII95801.1 - 0.00011 21.9 1.8 0.00019 21.1 1.2 1.3 1 0 0 1 1 1 1 Folate receptor family RRM_1 PF00076.17 KII95802.1 - 8e-13 47.8 0.0 4.6e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII95802.1 - 5.3e-08 32.7 0.0 1.3e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII95802.1 - 2.1e-07 30.6 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 KII95803.1 - 1.6e-06 28.0 20.5 0.011 16.0 1.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KII95803.1 - 9.1e-06 25.7 13.4 0.00024 21.2 2.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KII95803.1 - 9.3e-05 22.5 2.4 9.3e-05 22.5 1.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type MAR_sialic_bdg PF10564.4 KII95803.1 - 0.072 12.8 2.1 0.58 9.9 0.1 2.1 1 1 1 2 2 2 0 Sialic-acid binding micronemal adhesive repeat TfoX_N PF04993.8 KII95803.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 TfoX N-terminal domain zf-C2H2_jaz PF12171.3 KII95803.1 - 4.4 7.5 9.4 42 4.4 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAD_binding_6 PF00970.19 KII95804.1 - 6.4e-11 42.2 0.0 3.4e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KII95804.1 - 1.7e-09 38.1 0.0 5.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KII95804.1 - 7.9e-06 25.8 0.0 0.007 16.2 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KII95804.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Amidohydro_2 PF04909.9 KII95805.1 - 4.6e-09 36.2 0.0 6.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KII95805.1 - 2.4e-06 27.7 0.4 3e-06 27.4 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase Kinesin PF00225.18 KII95806.1 - 2.6e-105 351.8 0.0 4.3e-105 351.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Apolipoprotein PF01442.13 KII95806.1 - 0.2 11.1 10.7 0.039 13.4 1.5 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SNAPc19 PF15497.1 KII95806.1 - 0.67 10.1 4.6 0.53 10.5 1.4 2.2 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 EMP24_GP25L PF01105.19 KII95807.1 - 1.9e-48 164.6 0.5 2.2e-48 164.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.13 KII95808.1 - 1.5e-49 167.0 0.2 1.5e-49 167.0 0.2 1.6 2 0 0 2 2 2 1 RanBP1 domain DUF1681 PF07933.9 KII95808.1 - 5.5e-05 22.7 0.8 8.2e-05 22.2 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 KII95808.1 - 9.9e-05 22.0 0.3 0.00064 19.4 0.2 2.0 1 1 0 1 1 1 1 WH1 domain VID27 PF08553.5 KII95808.1 - 0.00038 18.8 7.7 0.00045 18.6 5.4 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein TraH_2 PF06871.6 KII95808.1 - 1.1 8.6 4.7 1.8 7.9 3.2 1.3 1 0 0 1 1 1 0 TraH_2 AAA_2 PF07724.9 KII95809.1 - 8.5e-35 120.1 0.0 1.5e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KII95809.1 - 1.3e-13 51.3 0.0 5e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KII95809.1 - 2.1e-11 43.5 0.0 5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KII95809.1 - 2.2e-05 24.2 0.0 5.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KII95809.1 - 9.5e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KII95809.1 - 0.0002 21.5 0.1 0.0038 17.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII95809.1 - 0.00022 22.0 0.1 0.00072 20.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 KII95809.1 - 0.00034 19.6 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 KII95809.1 - 0.00092 18.4 0.0 0.022 13.9 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KII95809.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KII95809.1 - 0.0039 16.6 0.1 0.01 15.2 0.1 1.7 1 1 1 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KII95809.1 - 0.017 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KII95809.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KII95809.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KII95809.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KII95809.1 - 0.022 14.8 0.0 0.067 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KII95809.1 - 0.032 13.6 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KII95809.1 - 0.034 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KII95809.1 - 0.038 13.4 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.7 KII95809.1 - 0.04 13.5 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KII95809.1 - 0.049 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KII95809.1 - 0.051 13.0 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 KII95809.1 - 0.057 12.4 0.0 0.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 KII95809.1 - 0.063 12.9 0.2 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KII95809.1 - 0.076 12.4 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 KII95809.1 - 0.078 12.9 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KII95809.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KII95809.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PhoH PF02562.11 KII95809.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Cactin_mid PF10312.4 KII95810.1 - 2.9e-60 202.8 6.1 2.9e-60 202.8 4.2 2.3 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KII95810.1 - 9.1e-58 193.2 6.3 1.8e-57 192.3 4.4 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cyclin PF08613.6 KII95811.1 - 5.5e-05 23.6 0.0 0.00042 20.7 0.0 2.0 2 0 0 2 2 2 1 Cyclin Sulphotransf PF09037.5 KII95811.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Stf0 sulphotransferase ThiF PF00899.16 KII95812.1 - 2.2e-46 157.0 0.0 8.5e-27 93.6 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 KII95812.1 - 7.5e-46 155.3 0.3 2e-45 154.0 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KII95812.1 - 1.1e-41 140.1 3.0 1.8e-26 91.4 0.2 3.5 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KII95812.1 - 1.5e-21 75.4 3.0 8.5e-19 66.6 0.8 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Cyclin PF08613.6 KII95813.1 - 3.5e-06 27.4 0.0 6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.3 KII95814.1 - 8.3e-126 420.3 0.0 1.2e-125 419.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KII95814.1 - 1.4e-48 165.3 0.0 2.4e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein DUF4519 PF15012.1 KII95814.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Fork_head PF00250.13 KII95815.1 - 1.4e-29 101.9 0.0 2.4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Fork head domain CIAPIN1 PF05093.8 KII95816.1 - 9.2e-30 102.6 4.7 1.4e-29 102.0 3.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CRA_rpt PF07046.6 KII95816.1 - 0.076 13.0 1.7 0.19 11.7 1.2 1.6 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat zf-HIT PF04438.11 KII95817.1 - 3.2e-09 36.2 10.7 4.8e-09 35.7 7.5 1.3 1 0 0 1 1 1 1 HIT zinc finger FoP_duplication PF13865.1 KII95817.1 - 0.3 11.5 4.7 0.72 10.3 3.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Med18 PF09637.5 KII95818.1 - 3.7e-07 29.9 0.0 0.00051 19.6 0.0 2.0 1 1 1 2 2 2 2 Med18 protein ADH_N PF08240.7 KII95819.1 - 9.2e-30 102.6 2.6 9.2e-30 102.6 1.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII95819.1 - 1.7e-19 69.6 0.4 3.1e-19 68.8 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KII95819.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KII95819.1 - 0.038 13.1 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KII95819.1 - 0.084 13.4 0.3 0.19 12.3 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain zf-RING_5 PF14634.1 KII95823.1 - 4.2e-08 32.7 7.3 7.1e-08 32.0 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KII95823.1 - 9.3e-07 28.7 3.9 1.8e-06 27.8 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII95823.1 - 6.3e-06 25.9 7.1 1.2e-05 25.0 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KII95823.1 - 4.6e-05 22.9 3.7 8.9e-05 22.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KII95823.1 - 6.7e-05 22.4 6.0 0.00012 21.6 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KII95823.1 - 0.0034 17.1 3.2 0.0059 16.3 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KII95823.1 - 0.0078 15.7 2.0 0.016 14.7 1.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KII95823.1 - 0.0083 15.8 1.3 0.024 14.3 0.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KII95823.1 - 0.018 15.1 4.2 0.019 15.0 2.0 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-P11 PF03854.9 KII95823.1 - 0.029 13.8 3.0 0.056 12.9 2.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 KII95823.1 - 0.03 14.1 4.0 0.071 12.9 2.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.6 KII95823.1 - 0.044 13.6 6.2 0.082 12.7 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF724 PF05266.9 KII95823.1 - 0.051 13.1 2.1 0.092 12.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prok-RING_4 PF14447.1 KII95823.1 - 0.33 10.5 4.0 0.78 9.3 2.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KII95823.1 - 0.64 9.9 5.6 1.8 8.5 3.5 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING C1_4 PF07975.7 KII95823.1 - 0.95 9.5 5.3 2.4 8.2 3.7 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Prok-RING_1 PF14446.1 KII95823.1 - 6.1 6.6 9.5 0.089 12.5 0.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF2236 PF09995.4 KII95824.1 - 2.8e-13 49.7 0.1 5.6e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Terminase_5 PF06056.7 KII95824.1 - 0.11 12.0 0.6 0.32 10.5 0.4 1.8 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) GAS2 PF02187.12 KII95825.1 - 1.1e-08 34.6 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Helicase_C PF00271.26 KII95827.1 - 3.3e-11 42.8 0.0 9.5e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KII95827.1 - 7.6e-08 32.0 0.0 5.1e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ArgK PF03308.11 KII95827.1 - 0.013 14.2 1.5 0.025 13.3 1.0 1.4 1 0 0 1 1 1 0 ArgK protein CAF-1_p150 PF11600.3 KII95827.1 - 0.34 10.2 47.9 0.57 9.5 33.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 KII95827.1 - 0.45 8.9 33.6 0.63 8.4 23.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 KII95827.1 - 2.7 7.7 22.0 3.9 7.2 15.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.6 KII95827.1 - 7.3 4.7 31.6 11 4.1 21.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Herpes_UL56 PF04534.7 KII95829.1 - 0.048 13.3 0.1 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF2514 PF10721.4 KII95829.1 - 0.2 11.3 1.9 0.23 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Transp_cyt_pur PF02133.10 KII95834.1 - 2.5e-74 250.4 34.9 2.9e-74 250.2 24.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Iso_dh PF00180.15 KII95835.1 - 6e-99 331.2 0.0 6.9e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.23 KII95838.1 - 0.0076 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF2373 PF10180.4 KII95839.1 - 5.7e-19 67.4 0.0 7.6e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Arf PF00025.16 KII95840.1 - 1.3e-70 236.1 0.0 1.5e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KII95840.1 - 2.2e-14 53.0 0.0 3.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KII95840.1 - 1.2e-13 50.5 0.4 2.6e-09 36.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KII95840.1 - 2e-10 40.2 0.0 2.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KII95840.1 - 1.7e-09 37.2 0.0 1.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII95840.1 - 4.5e-08 33.6 0.0 5.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KII95840.1 - 9.9e-05 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.27 KII95841.1 - 2.8e-27 93.5 7.0 7.9e-08 31.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat PBP1_TM PF14812.1 KII95841.1 - 0.082 13.2 1.5 0.18 12.1 1.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 KII95850.1 - 3.8e-28 96.3 7.4 4.6e-08 32.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF4232 PF14016.1 KII95850.1 - 0.086 12.5 3.9 0.33 10.6 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4232) Helicase_C PF00271.26 KII95852.1 - 4.6e-14 52.0 0.0 3.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Tet_JBP PF12851.2 KII95853.1 - 1.6e-10 40.5 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DASH_Dad2 PF08654.5 KII95853.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 Utp13 PF08625.6 KII95856.1 - 0.2 11.2 0.7 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain TLP-20 PF06088.6 KII95857.1 - 0.047 13.3 0.2 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Phage_HK97_TLTM PF06120.6 KII95857.1 - 0.18 11.0 4.8 0.32 10.2 3.3 1.3 1 0 0 1 1 1 0 Tail length tape measure protein AAA_13 PF13166.1 KII95857.1 - 0.28 9.5 4.4 0.41 9.0 3.0 1.1 1 0 0 1 1 1 0 AAA domain Upf2 PF04050.9 KII95858.1 - 0.0046 16.7 10.5 0.0082 15.9 7.2 1.3 1 0 0 1 1 1 1 Up-frameshift suppressor 2 DEAD PF00270.24 KII95860.1 - 4.2e-09 36.1 0.0 5.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase MerR-DNA-bind PF09278.6 KII95862.1 - 0.063 13.6 0.3 0.19 12.1 0.2 1.8 1 0 0 1 1 1 0 MerR, DNA binding SET PF00856.23 KII95864.1 - 6.6e-11 42.7 0.1 6.7e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 SET domain Aminotran_1_2 PF00155.16 KII95866.1 - 1.2e-75 254.8 0.0 1.5e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KII95866.1 - 4.3e-05 21.9 0.0 0.0001 20.7 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KII95866.1 - 4.5e-05 22.3 0.0 0.00014 20.7 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class-V Pertussis_S1 PF02917.9 KII95866.1 - 0.025 14.1 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Aminotran_3 PF00202.16 KII95867.1 - 2.6e-88 296.1 0.0 3.3e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_6 PF12697.2 KII95868.1 - 1.8e-30 106.5 0.5 2.8e-30 105.9 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII95868.1 - 1e-15 57.7 0.0 1.3e-13 50.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII95868.1 - 1.1e-15 57.8 0.0 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 KII95868.1 - 5.2e-06 26.0 0.0 2.1e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KII95868.1 - 6.1e-05 22.6 0.0 0.018 14.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KII95868.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 KII95868.1 - 0.0036 15.8 0.0 0.0086 14.5 0.0 1.5 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 KII95868.1 - 0.0085 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 KII95868.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 KII95868.1 - 0.019 14.7 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal cwf21 PF08312.7 KII95869.1 - 1.8e-14 53.3 11.7 1.8e-14 53.3 8.1 2.7 2 1 0 2 2 2 1 cwf21 domain DUF605 PF04652.11 KII95869.1 - 0.027 13.8 16.3 0.053 12.9 11.3 1.4 1 0 0 1 1 1 0 Vta1 like MT-A70 PF05063.9 KII95870.1 - 2.4e-56 190.0 0.0 3.6e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 MT-A70 adh_short PF00106.20 KII95871.1 - 1.5e-06 28.2 0.0 2.6e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII95871.1 - 0.0047 16.7 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII95871.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Asp PF00026.18 KII95873.1 - 1e-73 248.4 4.2 1.2e-73 248.1 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KII95873.1 - 4e-05 24.0 2.2 0.088 13.3 0.1 3.1 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KII95873.1 - 0.0022 17.5 0.1 0.0055 16.2 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KII95873.1 - 0.0058 16.5 0.9 0.025 14.5 0.4 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Borrelia_P13 PF05628.7 KII95873.1 - 0.088 12.6 2.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 0 Borrelia membrane protein P13 Asp PF00026.18 KII95874.1 - 1.7e-71 241.0 2.8 2.2e-71 240.7 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KII95874.1 - 5.4e-05 23.1 2.4 0.003 17.5 0.9 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KII95874.1 - 0.0048 16.4 0.2 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KII95874.1 - 0.01 16.2 0.9 4.5 7.8 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease DUF788 PF05620.6 KII95875.1 - 4e-44 150.4 0.0 4.6e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Myb_DNA-binding PF00249.26 KII95876.1 - 5e-39 132.1 8.5 6.6e-12 45.2 0.1 5.5 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KII95876.1 - 4.2e-34 116.4 2.3 7.4e-11 41.9 0.0 5.5 4 1 1 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KII95876.1 - 0.09 12.9 17.9 5.7 7.1 0.1 6.5 4 4 1 5 5 5 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 KII95876.1 - 0.51 10.2 9.6 20 5.1 2.1 4.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Bromo_TP PF07524.8 KII95877.1 - 5.9e-09 35.5 0.0 9.9e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 KII95877.1 - 2.5e-06 27.4 2.2 2.7e-06 27.3 0.4 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Flavokinase PF01687.12 KII95878.1 - 3.6e-37 127.0 0.0 4.3e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.14 KII95879.1 - 4.9e-10 39.5 0.4 7.4e-10 38.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.7 KII95880.1 - 8e-27 92.6 2.9 8.9e-27 92.4 2.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tricorn_C1 PF14684.1 KII95880.1 - 0.015 15.1 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain Longin PF13774.1 KII95881.1 - 2.3e-29 100.7 0.1 3.5e-29 100.1 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KII95881.1 - 4.8e-15 54.9 0.1 8.4e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF4646 PF15496.1 KII95882.1 - 3.2e-18 65.9 0.1 4.5e-17 62.2 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 KII95882.1 - 1.9 7.7 41.9 0.51 9.6 7.6 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spt5_N PF11942.3 KII95882.1 - 5 7.8 23.6 0.088 13.4 3.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal IF-2B PF01008.12 KII95883.1 - 2.5e-84 282.5 0.0 2.9e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Glyco_trans_4_4 PF13579.1 KII95883.1 - 0.0077 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF962 PF06127.6 KII95884.1 - 1.4e-22 79.3 3.6 5.8e-22 77.4 2.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) IPK PF03770.11 KII95885.1 - 2.9e-51 173.9 0.0 6.6e-51 172.7 0.0 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase Fork_head PF00250.13 KII95886.1 - 3.6e-23 81.3 0.2 4.1e-22 78.0 0.0 2.1 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 KII95886.1 - 1.8e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain MTP18 PF10558.4 KII95887.1 - 2.6e-54 183.1 0.3 3.3e-54 182.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) adh_short PF00106.20 KII95888.1 - 8.2e-26 90.8 1.8 1.1e-25 90.4 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII95888.1 - 1.9e-21 76.9 0.0 2.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII95888.1 - 1.9e-07 30.9 0.1 3.5e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KII95888.1 - 0.0027 17.3 0.9 0.0038 16.8 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KII95888.1 - 0.011 15.5 0.5 0.032 14.0 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_25 PF13649.1 KII95888.1 - 0.03 14.6 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain dUTPase PF00692.14 KII95890.1 - 1.5e-39 134.3 0.0 1.8e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase Peptidase_M43 PF05572.8 KII95893.1 - 4e-18 65.4 0.1 7.4e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KII95893.1 - 9e-07 29.0 0.8 1.5e-06 28.2 0.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KII95893.1 - 1e-06 28.9 0.5 1.5e-06 28.3 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KII95893.1 - 5.9e-05 23.5 0.1 0.00011 22.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KII95893.1 - 0.00029 20.4 2.5 0.00061 19.3 1.7 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KII95893.1 - 0.0086 15.7 0.5 0.017 14.8 0.4 1.6 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.3 KII95893.1 - 0.014 14.7 0.6 0.021 14.1 0.4 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 KII95893.1 - 0.014 14.2 0.3 0.019 13.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 ACBP PF00887.14 KII95894.1 - 1.6e-21 75.7 0.0 2.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein DUF605 PF04652.11 KII95894.1 - 0.23 10.7 14.9 0.33 10.3 10.3 1.3 1 0 0 1 1 1 0 Vta1 like ADH_N PF08240.7 KII95895.1 - 1.3e-22 79.6 1.9 2.9e-22 78.4 1.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KII95895.1 - 4.6e-20 71.4 0.1 7.7e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KII95895.1 - 0.0021 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vfa1 PF08432.5 KII95896.1 - 2e-36 125.7 0.0 2.3e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 KII95896.1 - 0.31 9.7 4.3 0.42 9.3 3.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pex14_N PF04695.8 KII95896.1 - 0.36 10.8 3.2 0.49 10.4 2.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rtf2 PF04641.7 KII95896.1 - 0.72 9.0 6.3 1 8.5 4.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger BRF1 PF07741.8 KII95896.1 - 1.4 9.2 12.4 3.6 7.8 8.6 1.7 1 1 0 1 1 1 0 Brf1-like TBP-binding domain APC_CDC26 PF10471.4 KII95896.1 - 7.2 7.4 8.2 1.7 9.4 2.4 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 Nucleoside_tran PF01733.13 KII95897.1 - 2.3e-38 132.1 8.9 2.3e-38 132.1 6.2 1.6 2 0 0 2 2 2 1 Nucleoside transporter Ank_2 PF12796.2 KII95899.1 - 2e-19 69.7 2.4 9.9e-10 38.6 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII95899.1 - 9e-19 66.2 1.5 2.2e-09 36.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KII95899.1 - 2.7e-16 59.2 0.5 2.7e-07 30.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII95899.1 - 2.4e-15 55.1 1.6 1.7e-05 24.6 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 KII95899.1 - 3.1e-15 56.2 3.7 1.1e-10 41.6 0.1 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) KilA-N PF04383.8 KII95899.1 - 0.00013 21.5 0.1 0.001 18.6 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain DUF3122 PF11320.3 KII95899.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Acyl-CoA_dh_C PF12806.2 KII95899.1 - 0.052 13.4 1.4 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like IncA PF04156.9 KII95899.1 - 3.7 7.0 4.9 12 5.4 0.4 2.3 2 0 0 2 2 2 0 IncA protein DSPn PF14671.1 KII95900.1 - 6.7e-39 133.0 0.0 6e-37 126.7 0.0 2.7 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KII95900.1 - 5e-17 61.7 0.0 9.9e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KII95900.1 - 9.1e-05 21.9 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KII95900.1 - 0.0057 16.7 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KII95900.1 - 0.048 13.9 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family URO-D PF01208.12 KII95901.1 - 6.1e-124 413.4 0.0 6.9e-124 413.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Amidase PF01425.16 KII95903.1 - 4.1e-99 332.4 0.0 4.7e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 KII95904.1 - 8.8e-07 28.7 11.1 1.8e-06 27.7 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 KII95905.1 - 2.3e-11 44.1 0.0 3.6e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KII95905.1 - 0.018 13.5 0.0 3.6 5.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 KII95906.1 - 2.9e-84 283.2 19.0 3.6e-84 282.9 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KII95906.1 - 3.2e-29 101.7 31.1 1.3e-24 86.5 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KII95906.1 - 5.8e-05 21.4 1.4 0.00012 20.4 1.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pex14_N PF04695.8 KII95906.1 - 0.13 12.3 0.8 0.39 10.7 0.1 2.2 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CopD PF05425.8 KII95907.1 - 0.022 14.9 6.2 0.066 13.4 3.9 2.2 1 1 1 2 2 2 0 Copper resistance protein D DUF3262 PF11660.3 KII95907.1 - 0.025 14.6 3.3 3.1 7.9 1.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) Ribosomal_L12 PF00542.14 KII95908.1 - 7.4e-20 70.7 4.2 7.1e-18 64.3 1.7 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 KII95908.1 - 0.71 10.3 8.3 0.15 12.4 0.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Not3 PF04065.10 KII95909.1 - 9e-94 313.0 22.2 1.3e-93 312.5 15.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KII95909.1 - 1.4e-43 147.9 8.5 1.4e-43 147.9 5.9 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family SH3_1 PF00018.23 KII95911.1 - 3.3e-22 77.6 0.0 4.4e-10 38.7 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KII95911.1 - 1.5e-19 69.3 0.2 8.3e-10 38.1 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KII95911.1 - 4.5e-16 58.0 0.2 2.4e-09 36.5 0.0 3.7 4 0 0 4 4 4 2 Variant SH3 domain PX PF00787.19 KII95911.1 - 2.7e-07 30.3 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 KII95911.1 - 0.00084 18.9 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 PB1 domain NDUFA12 PF05071.11 KII95912.1 - 3.3e-27 94.9 2.7 5.1e-27 94.3 1.9 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WHIM2 PF15613.1 KII95912.1 - 0.079 12.9 0.3 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 DAO PF01266.19 KII95913.1 - 2.8e-40 138.3 0.0 3.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribosomal_S7e PF01251.13 KII95914.1 - 9.3e-83 276.3 5.2 1.4e-82 275.7 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_11 PF13414.1 KII95914.1 - 3.4e-21 74.6 7.5 2.2e-15 56.0 0.0 2.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KII95914.1 - 3.4e-15 54.9 3.1 4.8e-05 22.7 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII95914.1 - 1.7e-10 40.0 2.5 0.0018 18.0 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KII95914.1 - 0.0012 19.1 0.2 0.0055 17.0 0.0 2.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KII95914.1 - 0.0016 18.4 3.0 0.0081 16.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KII95914.1 - 0.0042 17.7 0.0 0.17 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KII95914.1 - 0.017 15.2 1.1 0.037 14.1 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KII95914.1 - 0.023 14.6 0.8 2.1 8.3 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KII95914.1 - 0.029 14.9 0.1 2 9.2 0.1 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KII95914.1 - 0.059 13.2 0.5 0.15 11.8 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ras PF00071.17 KII95915.1 - 5.1e-47 159.2 0.0 7e-43 145.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KII95915.1 - 1.2e-19 70.9 0.0 2.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KII95915.1 - 4.7e-11 42.2 0.0 7.9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KII95915.1 - 1.3e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KII95915.1 - 0.00071 18.7 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KII95915.1 - 0.0062 16.4 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 KII95915.1 - 0.0086 15.3 0.1 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KII95915.1 - 0.011 15.2 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KII95915.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KII95915.1 - 0.034 13.3 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KII95915.1 - 0.042 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MHC_II_beta PF00969.14 KII95915.1 - 0.097 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Dynamin_N PF00350.18 KII95915.1 - 0.15 11.8 0.1 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 Dynamin family AMMECR1 PF01871.12 KII95916.1 - 3.9e-37 127.0 0.0 1.2e-35 122.1 0.0 2.0 1 1 0 1 1 1 1 AMMECR1 PPR_1 PF12854.2 KII95917.1 - 7.2e-08 31.7 5.3 7.1e-05 22.1 0.0 3.7 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 KII95917.1 - 3.3e-07 30.0 4.0 0.12 12.6 0.0 5.7 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KII95917.1 - 1e-06 28.5 1.2 0.24 11.3 0.0 4.5 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 KII95917.1 - 0.00011 21.9 2.6 0.083 12.9 0.0 4.5 5 0 0 5 5 5 1 PPR repeat Ribosomal_L3 PF00297.17 KII95918.1 - 5.4e-119 396.4 6.1 6.4e-119 396.1 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 MRC1 PF09444.5 KII95919.1 - 3e-13 50.2 25.7 3e-13 50.2 17.8 7.0 5 2 1 6 6 6 1 MRC1-like domain Acyltransferase PF01553.16 KII95921.1 - 3.1e-17 62.2 0.0 5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Na_Ca_ex PF01699.19 KII95922.1 - 1.8e-12 47.0 21.9 8e-08 31.9 3.8 3.1 2 2 1 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_88 PF07470.8 KII95923.1 - 3.1e-24 85.6 0.7 4.6e-24 85.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 KII95923.1 - 0.038 13.2 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Tho2 PF11262.3 KII95924.1 - 7.9e-67 225.3 0.0 1.1e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KII95924.1 - 2.7e-26 91.1 0.0 5.2e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_cyclohydroI PF01227.17 KII95925.1 - 1.6e-75 252.3 0.5 2.5e-75 251.6 0.4 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KII95925.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 KII95925.1 - 0.084 12.6 0.2 0.084 12.6 0.1 2.1 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.22 KII95926.1 - 4.2e-26 91.8 0.0 8e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KII95926.1 - 1.1e-10 41.9 0.0 7.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KII95926.1 - 5.9e-07 28.9 0.0 7.6e-06 25.3 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KII95926.1 - 7.3e-06 25.8 0.0 2.9e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KII95926.1 - 7.9e-06 24.6 0.0 0.006 15.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KII95926.1 - 5e-05 22.5 0.0 0.0039 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KII95926.1 - 0.002 17.8 0.0 0.0075 15.9 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KII95926.1 - 0.0021 17.5 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KII95926.1 - 0.0025 17.8 0.0 0.038 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KII95926.1 - 0.0053 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.1 KII95926.1 - 0.0087 16.4 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KII95926.1 - 0.01 16.6 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KII95926.1 - 0.017 14.9 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KII95926.1 - 0.025 14.0 0.2 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Ribosomal_S9 PF00380.14 KII95926.1 - 0.028 14.6 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S9/S16 NACHT PF05729.7 KII95926.1 - 0.036 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KII95926.1 - 0.037 14.3 0.2 1.1 9.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KII95926.1 - 0.06 13.4 0.0 0.9 9.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 KII95926.1 - 0.062 13.5 0.1 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KII95926.1 - 0.082 11.7 0.1 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KII95926.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KII95926.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 KII95926.1 - 0.18 11.6 0.1 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 GDPD PF03009.12 KII95927.1 - 8.4e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KII95928.1 - 1.4e-25 89.4 0.3 4.3e-15 55.8 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KII95928.1 - 3.1e-24 83.5 7.9 1.8e-07 30.6 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KII95928.1 - 5e-19 67.8 3.9 5.5e-07 29.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KII95928.1 - 1.2e-18 67.0 0.3 2.6e-06 27.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KII95928.1 - 5.2e-16 57.1 3.2 0.00017 21.5 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat SPX PF03105.14 KII95929.1 - 6.2e-34 118.0 3.2 2e-20 73.6 0.4 2.8 1 1 1 2 2 2 2 SPX domain DUF4631 PF15450.1 KII95929.1 - 0.044 12.0 0.2 0.058 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Pex2_Pex12 PF04757.9 KII95930.1 - 1.2e-52 178.5 1.3 1.5e-52 178.2 0.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KII95930.1 - 1.6e-07 31.2 1.6 1.6e-07 31.2 1.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KII95930.1 - 2.6e-06 27.1 0.9 2.6e-06 27.1 0.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KII95930.1 - 2.8e-05 23.6 0.6 2.8e-05 23.6 0.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KII95930.1 - 0.011 15.3 0.9 0.011 15.3 0.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KII95930.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KII95930.1 - 0.12 12.2 6.1 0.041 13.7 2.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KII95930.1 - 0.56 9.8 3.8 4.9 6.8 0.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KII95930.1 - 2.2 8.0 4.6 26 4.6 3.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Phage_ASH PF10554.4 KII95931.1 - 0.0071 16.6 0.6 0.11 12.8 0.2 2.2 1 1 0 2 2 2 1 Ash protein family DUF1772 PF08592.6 KII95931.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SSB PF00436.20 KII95932.1 - 1.7e-16 59.9 0.0 2.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family HBS1_N PF08938.5 KII95933.1 - 5e-13 48.9 0.3 1.1e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.22 KII95934.1 - 2.2e-35 121.8 0.0 3e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KII95934.1 - 2.1e-08 34.2 0.0 1.4e-07 31.6 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KII95934.1 - 6.2e-08 32.6 0.1 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KII95934.1 - 0.00021 20.8 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KII95934.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KII95934.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ras family CBM_20 PF00686.14 KII95936.1 - 0.0039 16.7 0.4 0.0061 16.1 0.3 1.5 1 1 0 1 1 1 1 Starch binding domain PP1c_bdg PF10488.4 KII95937.1 - 0.13 11.4 3.3 0.16 11.0 2.3 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region DUF605 PF04652.11 KII95937.1 - 8.1 5.7 17.9 9.7 5.4 12.4 1.1 1 0 0 1 1 1 0 Vta1 like Methyltransf_16 PF10294.4 KII95938.1 - 1.1e-44 151.9 0.0 1.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KII95938.1 - 0.00016 21.1 0.1 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KII95938.1 - 0.0024 18.4 0.0 0.0037 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KII95938.1 - 0.005 16.0 0.1 0.0065 15.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KII95938.1 - 0.038 14.0 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain BolA PF01722.13 KII95939.1 - 5.3e-17 61.5 0.1 8.8e-17 60.8 0.0 1.4 2 0 0 2 2 2 1 BolA-like protein Mt_ATP-synt_D PF05873.7 KII95940.1 - 8.2e-11 41.8 0.7 9.7e-11 41.5 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Cob_adeno_trans PF01923.13 KII95940.1 - 0.042 13.6 0.2 0.091 12.5 0.1 1.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase GAS PF13851.1 KII95940.1 - 0.12 11.5 3.2 0.16 11.1 2.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LsmAD PF06741.8 KII95940.1 - 0.24 11.5 3.9 1 9.5 0.2 2.2 2 0 0 2 2 2 0 LsmAD domain DUF2838 PF10998.3 KII95941.1 - 5.2e-38 129.3 9.3 1.2e-37 128.2 6.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) FAD_binding_4 PF01565.18 KII95942.1 - 8e-30 103.1 3.9 8e-30 103.1 2.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KII95942.1 - 8.1e-07 28.8 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like A_deamin PF02137.13 KII95943.1 - 6.6e-75 252.5 0.0 7.6e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Con-6 PF10346.4 KII95945.1 - 5.8e-11 41.6 0.8 7.9e-11 41.1 0.5 1.2 1 0 0 1 1 1 1 Conidiation protein 6 MS_channel PF00924.13 KII95947.1 - 6.6e-20 71.3 0.2 1.3e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.1 KII95947.1 - 0.0012 18.0 0.1 0.003 16.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KII95947.1 - 0.0014 17.7 0.0 0.0031 16.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KII95947.1 - 0.0037 17.0 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KII95947.1 - 0.014 15.5 0.1 0.035 14.2 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair PsbI PF02532.9 KII95947.1 - 2.3 7.9 5.9 7 6.3 4.1 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) APG6 PF04111.7 KII95948.1 - 2.2 7.2 24.4 2.9 6.8 16.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4239 PF14023.1 KII95948.1 - 3.8 6.8 9.5 5.4 6.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) AAA_13 PF13166.1 KII95948.1 - 4.9 5.4 20.3 7.3 4.9 14.1 1.2 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.21 KII95950.1 - 1.8e-53 180.6 0.0 2.3e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII95950.1 - 3.3e-13 48.6 1.6 5.8e-13 47.8 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TMP-TENI PF02581.12 KII95950.1 - 0.032 13.3 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI COX15-CtaA PF02628.10 KII95951.1 - 4.6e-92 308.1 13.2 5.5e-92 307.8 9.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RhaA PF06134.6 KII95953.1 - 0.078 11.8 0.2 2.6 6.8 0.0 2.0 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) PLD_C PF12357.3 KII95953.1 - 0.12 11.9 0.3 0.59 9.7 0.1 1.9 1 1 1 2 2 2 0 Phospholipase D C terminal PKD_channel PF08016.7 KII95956.1 - 0.0015 17.0 0.6 0.0015 17.0 0.4 2.3 2 0 0 2 2 2 2 Polycystin cation channel DUF3445 PF11927.3 KII95957.1 - 9.4e-60 202.0 0.0 2e-59 201.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) MFS_1 PF07690.11 KII95957.1 - 0.062 12.0 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1250 PF06855.7 KII95957.1 - 0.15 11.6 0.1 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) adh_short PF00106.20 KII95958.1 - 3.2e-23 82.4 0.5 6.3e-23 81.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KII95958.1 - 3.3e-13 49.6 0.0 6.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KII95958.1 - 3.5e-12 46.5 0.0 8.4e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KII95958.1 - 0.00018 21.0 0.0 0.00031 20.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPIP1 PF15338.1 KII95958.1 - 0.0011 18.8 0.2 0.49 10.2 0.0 2.7 3 0 0 3 3 3 2 p53-regulated apoptosis-inducing protein 1 Aldo_ket_red PF00248.16 KII95959.1 - 5.7e-41 140.2 0.0 7e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12D PF06522.6 KII95960.1 - 7.8e-14 51.1 0.1 9.1e-14 50.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DNA_ligase_aden PF01653.13 KII95962.1 - 0.017 14.0 0.7 0.031 13.2 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase adenylation domain AKNA PF12443.3 KII95962.1 - 1.2 9.1 6.7 3.1 7.8 0.0 3.1 3 0 0 3 3 3 0 AT-hook-containing transcription factor DivIC PF04977.10 KII95962.1 - 1.3 8.5 4.4 9 5.8 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF4530 PF15039.1 KII95962.1 - 4.9 7.0 11.3 0.99 9.3 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4530) Isochorismatase PF00857.15 KII95963.1 - 1.2e-28 100.1 0.0 1.6e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Hexokinase_2 PF03727.11 KII95964.1 - 1e-61 208.2 1.2 7.9e-38 130.0 0.0 2.9 2 1 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KII95964.1 - 2.8e-57 193.3 0.0 2.6e-55 186.9 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Sod_Fe_C PF02777.13 KII95965.1 - 9.5e-15 54.3 0.1 1.2e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.11 KII95966.1 - 5e-47 158.6 0.8 6.1e-47 158.3 0.6 1.0 1 0 0 1 1 1 1 DAD family PTP_N PF12453.3 KII95966.1 - 1.7 8.3 5.0 7.3 6.3 1.1 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal F-box-like PF12937.2 KII95967.1 - 2.8e-08 33.3 2.6 8.1e-08 31.8 1.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII95967.1 - 0.029 14.0 0.9 0.029 14.0 0.6 2.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KII95968.1 - 2.4e-09 36.7 1.7 5.4e-09 35.6 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KII95968.1 - 0.024 14.2 1.7 0.086 12.5 1.2 2.0 1 1 0 1 1 1 0 F-box domain Adap_comp_sub PF00928.16 KII95969.1 - 3.6e-36 124.6 0.0 1.2e-35 122.9 0.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DEADboxA PF12343.3 KII95971.1 - 0.14 12.3 4.2 0.19 12.0 2.9 1.2 1 0 0 1 1 1 0 Cold shock protein DEAD box A bZIP_1 PF00170.16 KII95972.1 - 4.5e-10 39.3 8.1 8.4e-10 38.4 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 KII95972.1 - 8.3e-09 35.5 25.0 5.4e-06 26.5 13.3 4.6 2 1 0 2 2 2 1 Aft1 HRA domain bZIP_2 PF07716.10 KII95972.1 - 0.00028 20.6 9.2 0.00053 19.7 6.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 KII95972.1 - 0.0012 19.3 18.4 0.0012 19.3 12.8 4.2 3 2 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Dicty_REP PF05086.7 KII95972.1 - 0.27 8.9 4.3 0.37 8.5 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein bZIP_Maf PF03131.12 KII95972.1 - 3.6 7.9 14.3 0.17 12.2 3.4 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Phospholip_A2_2 PF05826.7 KII95973.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase A2 WD40 PF00400.27 KII95974.1 - 7.1e-98 317.3 49.6 2.7e-12 46.0 0.1 9.8 9 0 0 9 9 9 9 WD domain, G-beta repeat NACHT PF05729.7 KII95974.1 - 1.4e-07 31.3 0.0 4.5e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 KII95974.1 - 1.3e-05 24.7 3.5 9.4 6.0 0.0 7.4 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 KII95974.1 - 3.5e-05 23.8 0.1 0.00026 21.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KII95974.1 - 0.0099 16.0 0.0 0.034 14.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KII95974.1 - 0.021 13.7 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 KII95974.1 - 0.032 13.9 0.0 0.17 11.5 0.0 2.2 2 1 1 3 3 3 0 Archaeal ATPase AAA_22 PF13401.1 KII95974.1 - 0.063 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KII95975.1 - 4.1e-20 71.7 0.2 6.7e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KII95975.1 - 2.5e-05 24.0 8.9 4.2e-05 23.3 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.3 KII95976.1 - 2.6e-39 134.7 0.0 5.4e-39 133.7 0.0 1.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 BCDHK_Adom3 PF10436.4 KII95976.1 - 0.098 12.1 0.2 1.1 8.8 0.1 2.4 3 0 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Kinesin PF00225.18 KII95978.1 - 4.3e-108 360.9 0.0 7.5e-108 360.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KII95978.1 - 1.3e-38 131.8 0.0 3e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KII95978.1 - 1.3e-13 51.0 0.1 1.2e-12 47.8 0.0 2.6 3 0 0 3 3 3 1 PH domain KIF1B PF12423.3 KII95978.1 - 8e-08 32.1 0.5 2e-07 30.9 0.3 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KII95978.1 - 1.3e-07 31.5 0.1 8.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 FHA domain Ribosomal_S4 PF00163.14 KII95979.1 - 3.2e-13 49.8 0.9 4.5e-13 49.4 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KII95979.1 - 2.1e-09 36.6 0.0 3.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF4407 PF14362.1 KII95980.1 - 6.8 5.5 6.7 14 4.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LIM_bind PF01803.11 KII95981.1 - 6e-55 185.9 0.0 7.4e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 LIM-domain binding protein Med26 PF08711.6 KII95982.1 - 4.7e-07 29.2 0.0 8.6e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.19 KII95982.1 - 7.4e-07 28.7 4.2 1.3e-06 27.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KII95982.1 - 0.23 11.5 4.0 0.39 10.8 2.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type HMG_box PF00505.14 KII95983.1 - 6.6e-21 74.3 0.5 1.1e-20 73.6 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KII95983.1 - 1.1e-10 41.7 1.0 2.3e-10 40.7 0.7 1.6 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 KII95983.1 - 0.00025 21.3 0.7 0.00033 20.9 0.3 1.3 1 1 0 1 1 1 1 YABBY protein DUF1074 PF06382.6 KII95983.1 - 0.00057 19.9 0.7 0.0007 19.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1074) WW PF00397.21 KII95984.1 - 0.0041 16.9 0.7 0.01 15.6 0.5 1.7 1 0 0 1 1 1 1 WW domain IFT20 PF14931.1 KII95985.1 - 9.4 6.1 10.4 18 5.2 7.2 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Cyt-b5 PF00173.23 KII95988.1 - 4.9e-11 42.2 0.1 8.8e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Med28 PF11594.3 KII95988.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 RGS PF00615.14 KII95989.1 - 8.7e-36 122.5 0.4 2.3e-35 121.2 0.2 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KII95989.1 - 4.1e-15 55.2 0.0 1.4e-07 31.1 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_M24 PF00557.19 KII95991.1 - 4.5e-55 186.4 0.1 5.9e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KII95991.1 - 3.2e-33 113.9 0.0 6.6e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AA_permease_2 PF13520.1 KII95992.1 - 9e-43 146.3 52.4 1.3e-42 145.8 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.22 KII95992.1 - 2.8e-32 111.6 0.0 1.1e-31 109.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AA_permease PF00324.16 KII95992.1 - 8.3e-25 87.0 41.7 1.1e-24 86.6 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease IF-2 PF11987.3 KII95992.1 - 2e-17 63.0 0.0 4.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KII95992.1 - 1.4e-15 57.1 4.3 1.7e-10 40.8 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KII95992.1 - 4.1e-06 26.7 0.0 1.1e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KII95992.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KII95992.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.16 KII95993.1 - 1.4e-68 229.6 0.4 1.6e-68 229.4 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KII95993.1 - 7.4e-14 51.2 2.1 3.6e-08 32.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KII95993.1 - 4e-10 39.2 0.0 4.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KII95993.1 - 8.5e-10 38.1 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KII95993.1 - 4.4e-08 33.0 0.0 6.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KII95993.1 - 5.6e-08 32.3 0.0 6.9e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KII95993.1 - 1.8e-06 28.4 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KII95993.1 - 0.0006 19.2 0.0 0.031 13.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KII95993.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KII95993.1 - 0.08 12.7 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.13 KII95993.1 - 0.15 11.0 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CMAS PF02353.15 KII95994.1 - 9.3e-58 195.4 0.0 1.2e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KII95994.1 - 1.4e-07 31.4 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KII95994.1 - 2.1e-06 28.2 0.0 5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KII95994.1 - 3.9e-05 24.0 0.0 9.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KII95994.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KII95994.1 - 0.0036 16.6 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KII95994.1 - 0.0049 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KII95994.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KII95994.1 - 0.039 13.2 0.0 0.1 11.9 0.0 1.8 1 1 0 1 1 1 0 Histone methylation protein DOT1 GCD14 PF08704.5 KII95994.1 - 0.044 13.2 0.0 0.092 12.2 0.0 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SAC3 PF12209.3 KII95994.1 - 0.063 13.4 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Methyltransf_24 PF13578.1 KII95994.1 - 0.076 13.8 0.2 2.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 KII95994.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S10 PF00450.17 KII95995.1 - 5.2e-81 272.9 0.3 7.1e-81 272.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2414 PF10309.4 KII95996.1 - 2.2e-06 27.2 0.0 4.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 KII95996.1 - 4.1e-05 23.9 4.7 4.1e-05 23.9 3.3 3.1 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 KH_1 PF00013.24 KII95997.1 - 3.1e-05 23.5 0.0 7.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KII95997.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 KII95997.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 KH domain EAF PF09816.4 KII95998.1 - 9.9e-23 80.1 0.0 1.6e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DTHCT PF08070.6 KII95998.1 - 0.1 13.2 9.2 0.27 11.9 3.4 3.0 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF2890 PF11081.3 KII95998.1 - 2.7 8.0 16.4 2.8 7.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ferritin_2 PF13668.1 KII95999.1 - 1e-32 112.9 0.4 1.5e-32 112.3 0.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain Macoilin PF09726.4 KII95999.1 - 7.6 4.6 15.7 12 4.0 10.6 1.4 2 0 0 2 2 2 0 Transmembrane protein DUF566 PF04484.7 KII95999.1 - 8.5 5.7 13.7 14 5.1 9.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Peptidase_S10 PF00450.17 KII96001.1 - 2.3e-104 349.8 0.2 2.8e-104 349.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KII96001.1 - 0.00087 19.2 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family UPAR_LY6 PF00021.16 KII96001.1 - 0.082 13.3 2.0 0.15 12.5 1.4 1.4 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Nop PF01798.13 KII96002.1 - 9.6e-59 196.9 0.5 9.6e-59 196.9 0.4 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KII96002.1 - 2.7e-27 94.3 0.1 4.7e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KII96002.1 - 2e-18 66.3 0.1 2e-18 66.3 0.1 2.0 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF3332 PF11810.3 KII96002.1 - 1.5 8.4 4.8 2.6 7.6 3.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) adh_short PF00106.20 KII96003.1 - 0.0016 18.3 0.0 0.38 10.6 0.0 2.8 2 1 1 3 3 3 2 short chain dehydrogenase ATP_bind_3 PF01171.15 KII96004.1 - 7e-18 64.7 0.1 1.3e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 KII96004.1 - 0.0042 17.4 0.0 0.0094 16.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KII96004.1 - 0.023 13.2 0.0 0.039 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF4428 PF14471.1 KII96004.1 - 0.027 14.2 1.5 0.067 12.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF2616 PF11077.3 KII96004.1 - 7.5 6.0 8.0 2.2 7.7 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) DUF2458 PF10454.4 KII96005.1 - 2.7e-11 43.5 0.4 4.1e-11 42.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 KII96005.1 - 0.011 15.1 0.3 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Abhydrolase_6 PF12697.2 KII96006.1 - 9.5e-15 55.0 0.3 1.6e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII96006.1 - 3.4e-08 33.3 0.5 0.00098 18.7 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KII96006.1 - 0.00027 20.7 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KII96006.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Epimerase PF01370.16 KII96007.1 - 2.1e-43 148.4 0.0 5.5e-43 147.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII96007.1 - 6.1e-10 38.2 0.0 1.3e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KII96007.1 - 1.3e-09 37.3 0.0 1.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KII96007.1 - 2.6e-08 33.1 0.1 0.00032 19.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KII96007.1 - 1.6e-05 23.9 0.3 0.0048 15.8 0.1 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KII96007.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KII96007.1 - 0.082 12.8 0.3 0.53 10.1 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase AlaDh_PNT_C PF01262.16 KII96007.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Bystin PF05291.6 KII96008.1 - 1.4e-120 401.8 0.0 2.1e-120 401.2 0.0 1.2 1 0 0 1 1 1 1 Bystin Abhydrolase_6 PF12697.2 KII96010.1 - 7.6e-26 91.3 0.0 1.1e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII96010.1 - 7.1e-10 38.8 0.0 1.5e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII96010.1 - 0.085 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PUF PF00806.14 KII96011.1 - 4.1e-16 57.4 0.0 0.00017 20.9 0.0 6.7 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Katanin_con80 PF13925.1 KII96011.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 con80 domain of Katanin Ribosomal_S11 PF00411.14 KII96012.1 - 9.6e-07 28.9 0.1 1.3e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Esterase_phd PF10503.4 KII96012.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 Esterase PHB depolymerase Glyco_transf_8 PF01501.15 KII96013.1 - 9.6e-32 110.2 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 KII96013.1 - 2.2e-18 67.0 0.2 1.1e-17 64.7 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_3 PF01596.12 KII96013.1 - 2.4e-05 23.4 0.0 5.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KII96013.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 KII96014.1 - 2.4e-41 141.7 0.0 3.5e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KII96014.1 - 5.2e-16 58.1 0.0 8.2e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glycos_transf_2 PF00535.21 KII96014.1 - 2.5e-14 53.3 0.9 1.1e-13 51.2 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KII96014.1 - 2.5e-10 40.5 0.4 1.2e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 NAD_binding_10 PF13460.1 KII96014.1 - 1.9e-08 34.5 0.0 4.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KII96014.1 - 1.6e-07 30.5 0.0 8.6e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KII96014.1 - 3.5e-05 22.8 0.0 5.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KII96014.1 - 0.00038 19.7 0.0 0.00068 18.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Glyco_tranf_2_2 PF10111.4 KII96014.1 - 0.0023 17.0 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 adh_short PF00106.20 KII96014.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KII96014.1 - 0.017 14.0 0.0 1.2 7.9 0.3 2.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein SNF2_N PF00176.18 KII96015.1 - 5.2e-65 219.1 0.0 8e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KII96015.1 - 1.7e-11 43.7 0.0 3.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KII96015.1 - 2.2e-05 24.1 6.3 2.2e-05 24.1 4.4 2.2 2 0 0 2 2 1 1 Ring finger domain DEAD PF00270.24 KII96015.1 - 3e-05 23.5 0.0 7.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KII96015.1 - 5.9e-05 22.6 6.7 5.9e-05 22.6 4.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KII96015.1 - 0.00024 21.0 5.6 0.00024 21.0 3.9 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KII96015.1 - 0.00034 20.5 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.2 KII96015.1 - 0.00038 20.5 1.6 0.0011 18.9 1.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 KII96015.1 - 0.00047 19.6 3.3 0.0013 18.2 2.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 KII96015.1 - 0.0035 16.9 4.7 0.0035 16.9 3.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KII96015.1 - 0.0044 16.7 1.2 0.011 15.4 0.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KII96015.1 - 0.014 15.2 5.2 0.014 15.2 3.6 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KII96015.1 - 0.017 14.9 0.8 0.017 14.9 0.5 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Acyl-CoA_dh_1 PF00441.19 KII96016.1 - 2.7e-27 95.7 0.3 3.7e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII96016.1 - 1.7e-19 69.0 1.6 3.6e-19 68.0 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KII96016.1 - 2.4e-16 59.2 0.1 8.4e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KII96016.1 - 1.4e-10 41.7 0.0 4.9e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KII96016.1 - 0.0078 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain dCMP_cyt_deam_1 PF00383.17 KII96018.1 - 7.7e-20 70.4 0.2 1e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KII96018.1 - 0.0032 17.3 1.5 0.034 13.9 1.0 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 KII96018.1 - 0.0093 15.6 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain IF3_C PF00707.17 KII96019.1 - 9.1e-08 31.7 0.0 2.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain PPR_2 PF13041.1 KII96020.1 - 1.1e-05 25.3 0.0 0.00028 20.7 0.0 3.4 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.1 KII96020.1 - 0.00017 21.6 2.9 1 9.8 0.0 5.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 KII96020.1 - 0.023 14.1 0.1 0.85 9.1 0.1 3.4 4 0 0 4 4 4 0 PPR repeat PPR PF01535.15 KII96020.1 - 0.3 11.1 1.8 47 4.2 0.0 4.3 4 0 0 4 4 4 0 PPR repeat MIF4G_like PF09088.6 KII96021.1 - 7.7e-61 204.8 0.0 1.4e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KII96021.1 - 1.1e-36 126.3 0.0 1.7e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KII96021.1 - 1.3e-06 27.9 0.0 2.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain UAA PF08449.6 KII96022.1 - 1.4e-60 204.8 5.2 1.6e-60 204.6 3.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KII96022.1 - 0.0043 17.0 11.3 0.0043 17.0 7.9 3.1 3 1 0 3 3 3 1 EamA-like transporter family Cyclin_N PF00134.18 KII96023.1 - 2.3e-13 49.8 0.0 3.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KII96023.1 - 1.9e-12 47.8 0.0 4.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin Alk_phosphatase PF00245.15 KII96023.1 - 0.00096 17.9 0.3 0.0015 17.2 0.2 1.2 1 0 0 1 1 1 1 Alkaline phosphatase SH3_9 PF14604.1 KII96024.1 - 1.6e-16 59.6 0.3 2.5e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KII96024.1 - 1.8e-13 49.6 0.2 3e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KII96024.1 - 2.2e-12 46.2 0.0 3.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CCDC14 PF15254.1 KII96027.1 - 1.8 6.8 7.7 2.9 6.1 5.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 F-box PF00646.28 KII96028.1 - 9.8e-05 21.9 0.1 0.00049 19.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain FYVE PF01363.16 KII96028.1 - 1.4 8.8 5.5 0.82 9.6 0.3 2.9 3 0 0 3 3 3 0 FYVE zinc finger Ribosomal_S14 PF00253.16 KII96028.1 - 2.8 7.4 7.8 0.27 10.6 1.6 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Ribosomal_L2_C PF03947.13 KII96029.1 - 1.1e-40 138.3 2.5 1.6e-40 137.8 1.7 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KII96029.1 - 2.4e-13 49.8 0.1 5.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4515 PF14988.1 KII96030.1 - 0.079 12.6 13.7 0.15 11.7 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF2454 PF10521.4 KII96031.1 - 5e-31 107.7 0.0 8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF2254 PF10011.4 KII96031.1 - 0.088 11.2 1.0 0.14 10.5 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Ribosomal_S25 PF03297.10 KII96033.1 - 4.1e-41 139.2 0.5 4.5e-41 139.1 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 KII96033.1 - 0.0012 18.2 0.3 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MerR PF00376.18 KII96033.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein Ftsk_gamma PF09397.5 KII96033.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Ftsk gamma domain PRKCSH-like PF12999.2 KII96034.1 - 3.3e-51 173.3 0.5 6.3e-51 172.4 0.4 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KII96034.1 - 1.3e-24 86.3 0.0 2.9e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KII96034.1 - 4.3e-09 37.0 0.3 1.2e-08 35.6 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TFIIIC_sub6 PF10419.4 KII96034.1 - 0.027 13.9 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 TFIIIC subunit FGGY_C PF02782.11 KII96035.1 - 7.2e-46 156.3 0.1 1e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KII96035.1 - 9.9e-22 77.4 0.0 7.3e-21 74.5 0.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KII96035.1 - 3.6e-05 23.1 2.1 0.0071 15.6 0.5 2.8 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family CmcH_NodU PF02543.10 KII96035.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase DUF4460 PF14687.1 KII96035.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Peptidase_S9_N PF02897.10 KII96036.1 - 2e-92 309.9 2.3 2.5e-92 309.6 1.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KII96036.1 - 2.4e-55 187.0 0.0 3.7e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KII96036.1 - 0.11 12.0 0.6 0.51 9.8 0.4 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Mito_carr PF00153.22 KII96037.1 - 2.2e-61 203.6 5.3 2.5e-21 75.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 KII96038.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like PDCD9 PF07147.7 KII96039.1 - 0.0016 17.3 2.6 0.0019 17.0 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Innate_immun PF12782.2 KII96039.1 - 0.16 11.1 8.1 0.26 10.4 5.6 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF3525 PF12039.3 KII96040.1 - 0.16 10.4 0.2 0.21 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) WD40 PF00400.27 KII96041.1 - 5.4e-14 51.4 11.6 2.4e-07 30.3 0.9 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KII96041.1 - 0.025 12.9 0.1 0.067 11.4 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.6 KII96041.1 - 0.026 14.2 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KII96041.1 - 0.047 11.5 0.0 0.32 8.7 0.0 1.9 2 0 0 2 2 2 0 IKI3 family Cyclin PF08613.6 KII96042.1 - 2.4e-39 135.1 1.0 2.7e-39 134.9 0.7 1.0 1 0 0 1 1 1 1 Cyclin adh_short PF00106.20 KII96044.1 - 2.2e-29 102.5 0.2 3.1e-29 102.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KII96044.1 - 5.3e-29 101.6 0.6 6.3e-29 101.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KII96044.1 - 7.8e-13 48.4 0.1 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KII96044.1 - 9.3e-05 22.1 0.0 0.00026 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KII96044.1 - 0.00073 18.7 0.1 0.00098 18.3 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) EF-hand_1 PF00036.27 KII96045.1 - 5.3e-28 94.1 9.5 9.1e-07 27.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KII96045.1 - 2.7e-25 88.2 1.5 2.2e-13 50.1 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KII96045.1 - 2.2e-21 73.7 5.4 1.8e-05 24.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KII96045.1 - 3e-20 70.5 9.0 4.1e-05 22.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KII96045.1 - 5.1e-15 54.8 13.3 2.1e-05 24.0 0.5 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 KII96045.1 - 2.7e-06 27.0 6.3 0.0015 18.2 0.4 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KII96045.1 - 3.1e-06 27.1 0.0 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KII96045.1 - 0.0063 16.3 0.1 0.86 9.5 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain Anthrax-tox_M PF09156.5 KII96045.1 - 0.07 12.2 0.2 0.27 10.2 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain TrmE_N PF10396.4 KII96046.1 - 1e-35 122.1 0.0 3.4e-35 120.4 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KII96046.1 - 6.3e-18 64.9 0.3 2.1e-17 63.2 0.2 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KII96046.1 - 9.8e-17 60.9 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KII96046.1 - 2.9e-05 23.9 0.0 0.00013 21.8 0.0 2.0 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 KII96046.1 - 0.001 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KII96046.1 - 0.0032 17.9 0.0 0.0061 17.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 KII96046.1 - 0.0075 17.0 0.0 0.021 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KII96046.1 - 0.0097 15.8 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KII96046.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KII96046.1 - 0.2 10.8 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 WD40 PF00400.27 KII96048.1 - 9.7e-15 53.8 7.2 3.8e-05 23.3 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat SUR7 PF06687.7 KII96051.1 - 0.72 9.3 16.0 0.1 12.1 0.6 2.3 2 0 0 2 2 2 0 SUR7/PalI family MBOAT PF03062.14 KII96053.1 - 9.8e-45 153.0 0.5 2e-44 152.0 0.1 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L18e PF00828.14 KII96054.1 - 6.3e-21 75.1 0.0 6.3e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 KII96055.1 - 3.1e-18 65.1 0.0 4.1e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII96055.1 - 2.3e-15 56.1 0.0 3.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII96055.1 - 4.4e-15 55.4 0.0 6.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GN3L_Grn1 PF08701.6 KII96056.1 - 3.9e-21 74.7 12.6 3.9e-21 74.7 8.7 2.1 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KII96056.1 - 9.5e-15 54.5 0.2 3e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KII96056.1 - 3.9e-08 32.6 0.0 6.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KII96056.1 - 9.6e-05 22.8 0.0 0.028 14.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 KII96056.1 - 0.00014 21.0 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 KII96056.1 - 0.00024 20.9 9.3 0.00048 19.9 0.1 3.4 2 2 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 KII96056.1 - 0.00077 18.7 0.2 0.046 12.9 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KII96056.1 - 0.0011 18.4 0.2 1.2 8.5 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KII96056.1 - 0.0012 18.8 1.3 0.03 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain CENP-T PF15511.1 KII96056.1 - 0.003 16.8 14.2 0.003 16.8 9.8 2.2 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T MobB PF03205.9 KII96056.1 - 0.0092 15.6 0.1 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 KII96056.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.8 KII96056.1 - 0.03 13.1 0.1 0.054 12.2 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KII96056.1 - 0.06 12.8 2.0 0.25 10.7 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 KII96056.1 - 0.08 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin cobW PF02492.14 KII96056.1 - 0.11 11.8 1.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 KII96056.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein F-box-like PF12937.2 KII96057.1 - 3e-06 26.8 2.4 3.1e-06 26.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like JmjC PF02373.17 KII96060.1 - 1.6e-14 54.1 0.0 4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KII96060.1 - 2.6e-05 23.8 0.0 0.00021 20.8 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain C1_1 PF00130.17 KII96060.1 - 0.0054 16.4 2.8 0.013 15.2 2.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ndc1_Nup PF09531.5 KII96060.1 - 0.45 8.8 3.7 0.66 8.3 2.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cupin_2 PF07883.6 KII96060.1 - 0.55 9.7 0.0 0.55 9.7 0.0 2.0 2 0 0 2 2 2 0 Cupin domain FYVE PF01363.16 KII96060.1 - 2.2 8.2 13.5 0.068 13.0 4.4 2.3 3 0 0 3 3 3 0 FYVE zinc finger Prok-RING_2 PF14445.1 KII96060.1 - 4 7.4 15.8 0.022 14.6 2.5 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 Response_reg PF00072.19 KII96061.1 - 3.3e-23 81.8 0.1 9.1e-17 61.0 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.14 KII96061.1 - 0.00037 19.2 0.0 0.00064 18.4 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ATG2_CAD PF13329.1 KII96061.1 - 0.061 12.9 0.2 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF3546 PF12066.3 KII96062.1 - 2.5e-12 46.7 0.8 7.8e-12 45.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KII96062.1 - 1.4e-11 45.0 0.6 1.4e-11 45.0 0.4 3.4 3 1 1 4 4 4 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 KII96062.1 - 3.6e-05 23.2 0.6 8.2e-05 22.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 KII96062.1 - 0.061 13.4 2.9 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 KII96062.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 KII96062.1 - 0.13 12.6 4.5 0.1 12.9 0.9 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.10 KII96062.1 - 2.4 7.9 6.4 0.11 12.2 0.4 1.8 2 0 0 2 2 2 0 BED zinc finger RRM_6 PF14259.1 KII96063.1 - 1.1e-06 28.5 0.0 3.9e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII96063.1 - 0.00013 21.5 0.0 0.022 14.3 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.20 KII96064.1 - 2.7e-16 59.4 0.0 7.5e-16 58.0 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KII96064.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PDH PF02153.12 KII96065.1 - 6.6e-13 48.1 0.0 9e-13 47.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KII96065.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KII96065.1 - 2.3e-05 24.7 0.0 6.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KII96065.1 - 0.0026 17.5 0.0 0.0055 16.5 0.0 1.6 1 1 0 1 1 1 1 ThiF family ApbA PF02558.11 KII96065.1 - 0.0032 16.9 0.0 0.0061 16.0 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KII96065.1 - 0.039 13.6 0.0 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KII96065.1 - 0.048 13.3 0.1 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KII96065.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KII96065.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CsiD PF08943.5 KII96065.1 - 0.14 11.0 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 CsiD Spt4 PF06093.8 KII96066.1 - 1e-29 102.2 0.2 1.2e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Ecotin PF03974.8 KII96067.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ecotin MFS_1 PF07690.11 KII96068.1 - 5e-32 110.9 38.7 1.6e-31 109.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KII96068.1 - 6.1e-11 41.5 26.9 9.4e-11 40.9 18.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF423 PF04241.10 KII96068.1 - 0.02 14.8 1.6 0.02 14.8 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF423) p450 PF00067.17 KII96069.1 - 3.7e-64 216.9 0.0 3.1e-56 190.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Lipoprotein_19 PF13617.1 KII96069.1 - 0.2 11.2 0.2 0.47 10.1 0.1 1.6 1 0 0 1 1 1 0 YnbE-like lipoprotein Med13_C PF06333.7 KII96070.1 - 1.3e-18 66.7 0.0 1.4e-16 60.1 0.0 2.5 1 1 0 1 1 1 1 Mediator complex subunit 13 C-terminal MerR PF00376.18 KII96070.1 - 0.033 13.7 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 MerR family regulatory protein ATP-synt_S1 PF05827.7 KII96071.1 - 1.5e-11 44.2 1.9 1.7e-10 40.7 0.0 2.0 1 1 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Abhydro_lipase PF04083.11 KII96072.1 - 1.9e-17 62.3 0.0 3.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KII96072.1 - 6.1e-09 36.0 1.1 9.9e-09 35.4 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII96072.1 - 0.00018 21.2 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KII96072.1 - 0.0039 16.7 0.1 0.0064 16.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2638 PF10937.3 KII96074.1 - 4.9e-14 53.3 4.4 1.3e-11 45.5 3.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) Proteasome PF00227.21 KII96075.1 - 3e-47 160.3 0.2 1.2e-46 158.3 0.2 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KII96075.1 - 3.4e-15 55.0 0.4 6.2e-15 54.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_5 PF04998.12 KII96076.1 - 8.8e-94 313.8 0.1 1.2e-93 313.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KII96076.1 - 1.9e-87 293.6 0.0 2.7e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KII96076.1 - 1.8e-66 223.1 0.0 4.3e-66 221.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KII96076.1 - 8.1e-39 132.8 0.0 3.7e-37 127.4 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KII96076.1 - 9.5e-33 112.1 0.0 2.1e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 KII96076.1 - 0.016 14.7 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 InsA N-terminal domain Mito_carr PF00153.22 KII96077.1 - 4.8e-50 167.2 5.8 1.6e-18 66.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 KII96078.1 - 1.6e-44 151.6 2.3 2.4e-44 151.0 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KII96078.1 - 2.1e-26 92.7 0.1 8e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KII96078.1 - 7.8e-21 74.7 0.4 1.3e-20 74.0 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KII96078.1 - 1.7e-19 69.0 0.2 3.9e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 KII96078.1 - 0.045 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF2433 PF10360.4 KII96079.1 - 3.1e-33 114.8 0.0 6.3e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 KII96079.1 - 2e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KII96079.1 - 6.2e-05 22.5 0.1 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NARP1 PF12569.3 KII96079.1 - 0.15 10.7 6.2 0.24 10.1 4.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 KII96079.1 - 0.57 10.0 10.0 1.2 8.9 6.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 KII96079.1 - 3.3 6.8 17.6 6.1 5.9 12.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GDI PF00996.13 KII96080.1 - 4.8e-52 176.7 0.0 1.4e-51 175.2 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KII96080.1 - 0.031 14.3 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.17 KII96081.1 - 8.7e-44 147.0 0.1 5.8e-23 80.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KII96081.1 - 7.8e-30 102.6 0.0 3.1e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KII96081.1 - 1.2e-16 60.2 0.0 9.3e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ric8 PF10165.4 KII96082.1 - 2.6e-66 224.3 0.0 3.7e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.4 KII96083.1 - 1.2e-16 60.7 0.0 1.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.1 KII96083.1 - 0.037 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 PIN domain KIAA1430 PF13879.1 KII96083.1 - 0.11 12.9 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 KIAA1430 homologue DUF2733 PF10813.3 KII96084.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) PMI_typeI PF01238.16 KII96085.1 - 1.3e-118 396.1 0.0 1.6e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KII96085.1 - 0.05 13.1 0.1 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Cupin domain SelP_N PF04592.9 KII96086.1 - 3.1 7.1 9.2 5.8 6.2 6.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LRR_8 PF13855.1 KII96092.1 - 0.00016 21.3 0.4 0.79 9.5 0.0 4.4 3 2 0 3 3 3 2 Leucine rich repeat IncA PF04156.9 KII96093.1 - 0.00028 20.5 0.1 0.00038 20.1 0.1 1.2 1 0 0 1 1 1 1 IncA protein DUF1993 PF09351.5 KII96093.1 - 0.028 14.3 2.3 0.04 13.8 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) APG6 PF04111.7 KII96093.1 - 0.088 11.8 6.6 0.12 11.4 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KII96093.1 - 0.15 10.9 3.1 0.24 10.3 2.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 KII96093.1 - 0.2 11.9 3.1 0.35 11.1 2.1 1.4 1 0 0 1 1 1 0 Snapin/Pallidin RmuC PF02646.11 KII96093.1 - 0.23 10.2 4.4 0.36 9.6 3.0 1.2 1 0 0 1 1 1 0 RmuC family FUSC PF04632.7 KII96093.1 - 0.26 9.6 5.0 0.36 9.2 3.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF848 PF05852.6 KII96093.1 - 0.29 10.9 5.2 0.46 10.3 3.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_TATA_bd PF12325.3 KII96093.1 - 0.44 10.2 9.1 0.74 9.5 6.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KII96093.1 - 1.2 9.0 8.8 1.8 8.4 6.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding WD40 PF00400.27 KII96096.1 - 2.8e-18 65.0 9.4 2.8e-11 42.8 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3361 PF11841.3 KII96096.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) UBN2_2 PF14227.1 KII96102.1 - 1.5e-05 24.5 0.0 1.7e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KII96102.1 - 1.9e-05 24.4 0.0 2.1e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.1 KII96103.1 - 0.0061 16.2 3.0 0.012 15.3 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KII96103.1 - 0.34 10.4 6.8 0.72 9.3 4.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TB PF00683.12 KII96108.1 - 0.2 11.2 2.4 0.36 10.4 1.7 1.6 1 1 0 1 1 1 0 TB domain Striatin PF08232.7 KII96109.1 - 1 9.6 0.0 1 9.6 0.0 4.2 4 0 0 4 4 4 0 Striatin family DUF4218 PF13960.1 KII96111.1 - 0.0028 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transpos_assoc PF13963.1 KII96112.1 - 0.018 15.0 0.2 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Transposase-associated domain Nop14 PF04147.7 KII96112.1 - 2.3 6.0 14.1 2.6 5.8 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KII96112.1 - 2.7 5.9 5.6 3.1 5.7 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 KII96113.1 - 0.046 14.1 0.3 0.046 14.1 0.2 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF639 PF04842.7 KII96115.1 - 5.3 5.0 5.3 6 4.8 3.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PAT1 PF09770.4 KII96117.1 - 1.8 6.6 7.6 2.1 6.4 5.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1059 PF06348.6 KII96118.1 - 0.15 11.8 0.8 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) PPR_2 PF13041.1 KII96119.1 - 1.6e-47 159.2 0.5 8e-12 44.9 0.0 13.8 10 2 4 14 14 14 7 PPR repeat family PPR PF01535.15 KII96119.1 - 5.8e-36 119.9 6.2 7.3e-05 22.4 0.0 14.6 16 0 0 16 16 16 6 PPR repeat PPR_3 PF13812.1 KII96119.1 - 3.2e-31 104.9 16.0 0.00048 20.1 0.0 16.2 18 0 0 18 18 18 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 KII96119.1 - 2e-28 97.5 0.0 7.9e-06 25.2 0.0 10.5 12 0 0 12 12 12 4 PPR repeat TPR_14 PF13428.1 KII96119.1 - 2.6e-12 46.2 6.0 1.7 9.5 0.0 11.7 12 1 1 13 13 13 1 Tetratricopeptide repeat TPR_19 PF14559.1 KII96119.1 - 0.0058 16.9 2.8 12 6.2 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Clathrin PF00637.15 KII96119.1 - 0.075 12.6 0.0 0.33 10.5 0.0 2.2 1 0 0 1 1 1 0 Region in Clathrin and VPS Mito_fiss_reg PF05308.6 KII96119.1 - 0.079 12.3 2.5 0.17 11.2 1.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator COX5A PF02284.11 KII96119.1 - 0.081 12.8 0.1 21 5.0 0.0 4.3 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va TPR_16 PF13432.1 KII96119.1 - 0.35 11.5 10.7 3.5 8.4 0.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Nop14 PF04147.7 KII96121.1 - 0.047 11.6 8.1 0.066 11.1 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KII96121.1 - 0.29 9.1 12.4 0.42 8.5 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KII96121.1 - 0.57 7.7 7.8 0.76 7.3 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 KII96121.1 - 2.6 6.2 15.8 3.4 5.8 10.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Sec63 PF02889.11 KII96122.1 - 2.1e-30 106.0 0.0 3.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KII96122.1 - 5e-17 61.3 0.1 1.2e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 KII96123.1 - 6.3e-46 154.3 0.7 3.3e-24 84.5 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KII96123.1 - 2.8e-19 69.6 0.0 6e-13 48.9 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KII96123.1 - 1.7e-08 34.4 0.1 0.00054 20.0 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KII96123.1 - 1.6e-05 25.0 2.5 0.00032 20.8 0.2 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KII96123.1 - 0.00049 19.8 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 KII96123.1 - 0.00052 20.0 0.2 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 KII96123.1 - 0.0085 16.0 0.2 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KII96123.1 - 0.071 12.8 0.1 0.7 9.5 0.0 2.6 3 0 0 3 3 3 0 AhpC/TSA family Disulph_isomer PF06491.6 KII96123.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.9 1 0 0 1 1 1 0 Disulphide isomerase CGI-121 PF08617.5 KII96124.1 - 2.3e-41 141.1 0.1 2.7e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Actino_peptide PF14408.1 KII96126.1 - 0.0056 16.5 0.2 0.0075 16.1 0.1 1.3 1 1 0 1 1 1 1 Ribosomally synthesized peptide in actinomycetes Pil1 PF13805.1 KII96127.1 - 1.1 8.3 5.3 1.8 7.6 3.7 1.3 1 0 0 1 1 1 0 Eisosome component PIL1 VWA_2 PF13519.1 KII96128.1 - 2.7e-14 53.6 0.3 2.7e-14 53.6 0.2 2.3 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 KII96128.1 - 3.6e-12 44.7 15.9 0.00038 19.7 0.2 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 KII96128.1 - 1.8e-08 34.2 0.1 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KII96128.1 - 1.1e-07 31.7 1.0 1.8e-07 31.0 0.7 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Amidase PF01425.16 KII96131.1 - 7.7e-68 229.3 0.5 3.1e-65 220.7 0.1 2.1 2 0 0 2 2 2 2 Amidase MobB PF03205.9 KII96132.1 - 2.8e-09 36.8 0.0 6.6e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 KII96132.1 - 7.4e-05 22.5 0.0 0.0015 18.3 0.0 2.6 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.13 KII96132.1 - 0.00048 19.6 0.0 0.00095 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 KII96132.1 - 0.0029 17.5 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KII96132.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KII96132.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KII96132.1 - 0.2 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ORC6 PF05460.8 KII96132.1 - 1.6 7.7 5.1 2.4 7.1 3.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Daxx PF03344.10 KII96132.1 - 2.9 6.2 7.1 4.1 5.7 4.9 1.1 1 0 0 1 1 1 0 Daxx Family WGG PF10273.4 KII96133.1 - 3e-23 81.7 0.2 4.9e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KII96133.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) MFS_1 PF07690.11 KII96134.1 - 1.3e-24 86.5 15.9 1.3e-24 86.5 11.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KII96134.1 - 0.083 12.9 1.3 0.72 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) FxsA PF04186.8 KII96135.1 - 0.02 14.5 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Cyclin_N PF00134.18 KII96136.1 - 1.2e-11 44.3 0.5 1.1e-10 41.1 0.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KII96136.1 - 0.00027 20.8 0.3 0.029 14.2 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 KII96136.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Ldh_1_N PF00056.18 KII96137.1 - 6.9e-42 142.6 0.2 9.3e-42 142.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KII96137.1 - 8.5e-42 142.8 0.0 1.2e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_10 PF13460.1 KII96137.1 - 0.0025 17.8 0.6 0.0046 16.9 0.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KII96137.1 - 0.0037 16.0 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KII96137.1 - 0.016 15.5 0.1 0.049 13.9 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KII96137.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 KII96137.1 - 0.042 13.1 0.2 0.53 9.5 0.1 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase MDMPI_N PF11716.3 KII96137.1 - 0.06 13.7 0.8 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain TPR_12 PF13424.1 KII96141.1 - 2.6e-12 46.5 7.1 0.0014 18.5 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII96141.1 - 6.4e-07 28.8 6.8 0.0045 16.7 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KII96141.1 - 1.7e-06 27.3 1.8 0.00094 18.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KII96141.1 - 5e-06 26.0 2.6 0.024 14.2 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KII96141.1 - 9.5e-06 25.0 3.2 0.026 14.2 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KII96141.1 - 0.0006 20.4 7.6 4.2 8.1 0.0 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KII96141.1 - 0.0063 16.4 3.3 0.55 10.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc5 PF12862.2 KII96141.1 - 0.0073 16.1 3.0 3 7.7 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 KII96141.1 - 0.048 13.8 4.5 1.1 9.4 0.0 4.5 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KII96141.1 - 0.076 13.3 3.5 2.8 8.3 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3150 PF11348.3 KII96141.1 - 0.098 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) TPR_14 PF13428.1 KII96141.1 - 0.14 12.8 0.1 0.14 12.8 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KII96141.1 - 1.3 9.6 4.5 5.5 7.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PMT PF02366.13 KII96143.1 - 3.4e-80 268.9 12.3 3.4e-80 268.9 8.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KII96143.1 - 1.1e-45 155.4 1.7 2.2e-45 154.5 1.2 1.5 1 0 0 1 1 1 1 MIR domain DUF1240 PF06836.7 KII96143.1 - 0.17 12.1 1.7 2.3 8.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Med13_N PF11597.3 KII96144.1 - 0.15 10.7 0.1 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Pyr_redox_3 PF13738.1 KII96145.1 - 3e-22 79.6 0.0 2.9e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KII96145.1 - 4.6e-12 45.5 0.0 1.2e-09 37.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KII96145.1 - 8.5e-12 44.0 0.0 1.8e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KII96145.1 - 1.3e-10 41.3 4.5 0.0018 18.0 0.2 4.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KII96145.1 - 1.4e-09 38.1 0.0 0.0013 18.6 0.0 3.3 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KII96145.1 - 1.3e-08 34.1 2.4 0.047 12.5 0.0 3.7 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KII96145.1 - 3.8e-07 30.0 1.6 1.6e-05 24.8 0.0 3.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KII96145.1 - 4.8e-06 25.9 0.0 0.22 10.5 0.0 3.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KII96145.1 - 5.6e-05 23.4 0.1 0.0037 17.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KII96145.1 - 9.6e-05 21.0 0.5 0.35 9.2 0.0 3.3 4 0 0 4 4 4 2 HI0933-like protein Shikimate_DH PF01488.15 KII96145.1 - 0.00019 21.5 0.0 0.55 10.3 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KII96145.1 - 0.0044 16.1 0.4 1.3 8.0 0.0 2.5 3 0 0 3 3 3 2 Thi4 family Lycopene_cycl PF05834.7 KII96145.1 - 0.019 13.9 1.3 7.1 5.4 0.1 3.5 4 0 0 4 4 4 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KII96145.1 - 0.051 12.4 0.5 0.3 9.8 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.14 KII96145.1 - 0.056 12.4 0.3 0.8 8.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 KII96145.1 - 0.065 12.6 0.3 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KII96145.1 - 0.26 10.1 0.1 9.4 4.9 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Cpn60_TCP1 PF00118.19 KII96147.1 - 3.4e-137 458.0 12.9 3.9e-137 457.7 8.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_28 PF00295.12 KII96148.1 - 1e-48 165.9 3.5 1.3e-48 165.6 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 KII96149.1 - 2.3e-49 168.1 6.7 3e-49 167.7 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RA PF00788.18 KII96150.1 - 1.4e-12 47.8 0.0 3.1e-09 37.1 0.0 3.8 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 KII96150.1 - 4.8e-06 25.8 0.3 2.2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 SH3 domain MIP-T3 PF10243.4 KII96150.1 - 9.7e-05 21.0 12.9 9.7e-05 21.0 8.9 3.2 2 2 1 3 3 3 1 Microtubule-binding protein MIP-T3 SH3_9 PF14604.1 KII96150.1 - 0.00031 20.2 0.1 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain CCDC84 PF14968.1 KII96150.1 - 4.9 6.5 24.5 0.055 12.9 10.2 2.3 2 0 0 2 2 2 0 Coiled coil protein 84 DPBB_1 PF03330.13 KII96152.1 - 0.00075 19.4 0.2 0.0012 18.7 0.2 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KII96152.1 - 0.046 13.4 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Barwin family Thaumatin PF00314.12 KII96153.1 - 5.7e-64 215.4 12.8 6.5e-64 215.3 8.9 1.0 1 0 0 1 1 1 1 Thaumatin family Toxin_47 PF15527.1 KII96153.1 - 0.0033 17.1 1.2 0.36 10.5 0.0 2.4 1 1 1 2 2 2 2 Putative toxin 47 Npa1 PF11707.3 KII96154.1 - 3.7e-75 252.9 0.0 2.8e-74 250.1 0.0 2.5 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal SDA1 PF05285.7 KII96154.1 - 0.45 9.7 10.3 0.94 8.6 7.2 1.4 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 KII96154.1 - 1.3 8.1 0.9 2.7 7.1 0.6 1.5 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_6 PF12697.2 KII96155.1 - 5.9e-19 68.8 1.6 7.4e-19 68.5 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KII96155.1 - 5.4e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pec_lyase_C PF00544.14 KII96156.1 - 3.1e-40 137.7 8.1 5e-40 137.1 5.6 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KII96156.1 - 0.0016 18.2 16.3 0.074 12.8 11.4 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 KII96156.1 - 0.016 14.3 7.0 0.016 14.3 3.3 1.8 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) YrhC PF14143.1 KII96157.1 - 0.035 14.0 0.1 0.068 13.1 0.0 1.6 1 1 1 2 2 2 0 YrhC-like protein Rsa3 PF14615.1 KII96158.1 - 1.3e-11 43.5 0.1 1.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Macoilin PF09726.4 KII96158.1 - 0.088 11.0 7.6 0.1 10.8 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 KII96158.1 - 0.18 11.5 7.5 0.37 10.4 5.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KIAA1328 PF15369.1 KII96158.1 - 0.23 11.2 2.1 0.27 11.0 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Ashwin PF15323.1 KII96158.1 - 0.52 10.2 13.4 0.83 9.6 9.3 1.4 1 0 0 1 1 1 0 Developmental protein DUF605 PF04652.11 KII96158.1 - 0.99 8.7 21.2 1.2 8.4 14.7 1.1 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 KII96158.1 - 3.7 5.1 6.8 4.1 4.9 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIRC PF00731.15 KII96159.1 - 3.3e-64 214.7 1.3 6.6e-64 213.7 0.5 1.9 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 KII96159.1 - 2.6e-62 209.2 0.0 3.7e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KII96159.1 - 2.6e-12 46.8 0.0 5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KII96159.1 - 6.7e-06 25.5 0.0 1.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KII96159.1 - 3.4e-05 22.7 0.0 0.0012 17.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KII96159.1 - 0.00033 20.1 0.0 0.0063 15.9 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.1 KII96159.1 - 0.009 16.1 0.3 20 5.3 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.14 KII96159.1 - 0.012 14.7 0.1 0.026 13.6 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 KII96159.1 - 0.015 14.7 0.5 0.18 11.1 0.0 2.5 2 1 0 2 2 2 0 Propionate catabolism activator ATP-grasp_3 PF02655.9 KII96159.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SCO1-SenC PF02630.9 KII96160.1 - 4.3e-54 182.7 0.0 5.3e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KII96160.1 - 2.7e-06 27.0 0.0 2.3e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KII96160.1 - 4.2e-05 23.5 0.0 8.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF4051 PF13260.1 KII96160.1 - 0.061 12.6 1.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) LCAT PF02450.10 KII96161.1 - 6.8e-71 239.2 0.6 9.4e-70 235.5 0.4 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 KII96161.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 KII96161.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) NDUF_B7 PF05676.8 KII96162.1 - 7.7e-31 105.3 1.3 9.1e-31 105.0 0.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KII96162.1 - 0.011 15.4 1.1 0.015 15.0 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Bac_rhamnosid PF05592.6 KII96164.1 - 8.1e-26 90.2 4.5 3.5e-23 81.6 1.9 2.7 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KII96164.1 - 9.9e-07 27.7 1.2 1.5e-06 27.2 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 KII96164.1 - 2.8e-05 22.9 0.7 4e-05 22.4 0.5 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 KII96164.1 - 0.049 12.3 0.5 0.13 10.9 0.3 1.6 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Wzy_C PF04932.10 KII96167.1 - 0.0051 16.6 2.8 0.087 12.6 0.1 2.5 2 0 0 2 2 2 2 O-Antigen ligase YfzA PF14118.1 KII96167.1 - 0.041 14.0 6.2 0.15 12.1 0.5 2.6 1 1 1 2 2 2 0 YfzA-like protein GD_AH_C PF04295.8 KII96167.1 - 0.046 12.3 0.1 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus AA_permease_2 PF13520.1 KII96168.1 - 6.4e-77 258.8 35.4 7.9e-77 258.5 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease TPR_12 PF13424.1 KII96170.1 - 9.8e-25 86.3 46.0 1.8e-09 37.4 3.6 7.6 3 2 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 KII96170.1 - 3.5e-09 36.2 41.4 9.9e-05 22.1 1.8 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 KII96170.1 - 1.3e-06 27.6 5.6 0.03 13.9 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII96170.1 - 1e-05 25.0 19.0 0.12 12.3 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII96170.1 - 0.00054 19.5 26.4 0.042 13.5 1.8 5.7 5 2 1 6 6 6 4 TPR repeat TPR_8 PF13181.1 KII96170.1 - 0.0017 17.9 6.4 13 5.8 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.2 KII96170.1 - 0.022 14.6 12.0 0.62 9.8 0.3 4.3 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 KII96170.1 - 0.026 14.1 4.2 6.7 6.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF627) TPR_16 PF13432.1 KII96170.1 - 0.045 14.4 0.5 0.045 14.4 0.3 6.3 6 2 1 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KII96170.1 - 0.083 12.6 1.8 0.22 11.3 0.1 2.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Polyketide_cyc2 PF10604.4 KII96171.1 - 5.1e-07 29.9 0.1 1.1e-05 25.6 0.1 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KII96171.1 - 0.059 13.3 0.5 0.073 13.0 0.4 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_4 PF01565.18 KII96172.1 - 3.3e-26 91.4 2.0 5.2e-26 90.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KII96172.1 - 3.2e-05 23.7 0.0 8.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF2235 PF09994.4 KII96173.1 - 7.8e-76 255.0 0.0 1e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 KII96173.1 - 0.003 17.3 0.0 0.93 9.1 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KII96173.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 KII96173.1 - 0.14 11.6 0.1 0.27 10.6 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) An_peroxidase PF03098.10 KII96174.1 - 7.1e-76 255.6 0.0 1.2e-73 248.2 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KII96174.1 - 4.1e-07 28.8 0.0 1.1e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Asp23 PF03780.8 KII96174.1 - 0.24 11.6 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Asp23 family UPRTase PF14681.1 KII96175.1 - 1.3e-76 256.4 0.0 1.5e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KII96175.1 - 9.9e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EMG1 PF03587.9 KII96176.1 - 1.4e-73 246.5 0.0 1.7e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CRAL_TRIO PF00650.15 KII96177.1 - 8.4e-36 122.8 0.0 1.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KII96177.1 - 2.5e-15 56.3 0.6 2.5e-15 56.3 0.4 2.0 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KII96177.1 - 0.0059 16.5 0.0 0.028 14.3 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain TPR_12 PF13424.1 KII96179.1 - 4.4e-29 100.2 32.4 1.2e-07 31.5 2.1 6.8 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 KII96179.1 - 1.8e-16 59.4 21.0 0.0039 17.0 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 KII96179.1 - 1.5e-11 43.2 11.4 0.51 10.3 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 KII96179.1 - 8.2e-08 31.7 17.2 0.00038 20.0 0.0 5.4 3 2 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 KII96179.1 - 1.8e-07 30.4 8.1 6.6 6.5 0.1 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat DUF3856 PF12968.2 KII96179.1 - 1.3e-06 28.2 10.4 0.3 10.9 0.4 4.9 3 2 2 5 5 5 3 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 KII96179.1 - 2.4e-05 24.8 16.6 0.38 11.4 0.0 5.5 2 2 4 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KII96179.1 - 0.00048 20.5 17.0 4.2 8.2 0.0 8.2 6 2 2 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 KII96179.1 - 0.0013 18.8 17.5 0.59 10.3 0.2 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KII96179.1 - 0.0032 17.7 13.2 1.4 9.2 0.0 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KII96179.1 - 0.027 14.8 6.9 57 4.4 0.0 7.2 8 1 0 8 8 7 0 Tetratricopeptide repeat DUF627 PF04781.7 KII96179.1 - 0.093 12.3 0.8 0.8 9.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Actin PF00022.14 KII96182.1 - 5.6e-155 515.5 0.0 6.4e-155 515.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KII96182.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ank_2 PF12796.2 KII96183.1 - 1.4e-08 34.8 0.0 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KII96183.1 - 9.1e-06 26.0 0.1 0.008 16.6 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KII96183.1 - 0.00096 18.8 0.1 5.6 6.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KII96183.1 - 0.0012 18.8 0.0 3.9 8.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KII96183.1 - 0.0038 17.4 0.1 1.1 9.6 0.0 3.4 2 1 2 4 4 4 1 Ankyrin repeats (many copies) 4HBT_3 PF13622.1 KII96183.1 - 0.38 10.4 3.2 0.62 9.7 2.2 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily F-box-like PF12937.2 KII96184.1 - 0.0059 16.3 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 F-box-like Abhydrolase_9_N PF15420.1 KII96189.1 - 0.51 10.0 4.6 0.37 10.5 1.3 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Actin PF00022.14 KII96191.1 - 2.3e-153 510.2 0.0 2.6e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KII96191.1 - 0.069 13.5 0.0 0.26 11.6 0.0 1.9 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Actin PF00022.14 KII96192.1 - 2.5e-127 424.5 0.1 3.4e-125 417.5 0.1 2.4 1 1 0 1 1 1 1 Actin zf-MYND PF01753.13 KII96193.1 - 2.2e-10 40.2 8.9 4.4e-10 39.2 6.2 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KII96193.1 - 0.04 13.1 1.3 0.087 12.1 0.9 1.5 1 0 0 1 1 1 0 Life-span regulatory factor DcpS_C PF11969.3 KII96194.1 - 3.3e-11 43.4 0.3 1.2e-09 38.3 0.2 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Solute_trans_a PF03619.11 KII96195.1 - 7e-77 258.4 10.5 8.6e-77 258.1 7.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HD PF01966.17 KII96196.1 - 2.8e-13 49.9 0.1 7e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 HD domain Peptidase_S10 PF00450.17 KII96198.1 - 2.1e-84 284.0 0.0 2.7e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Exo_endo_phos PF03372.18 KII96201.1 - 9.4e-23 81.4 0.3 1.8e-22 80.5 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_3 PF13570.1 KII96201.1 - 0.075 13.3 5.2 6.8 7.1 0.1 4.8 3 1 1 4 4 4 0 PQQ-like domain DcpS_C PF11969.3 KII96203.1 - 2.9e-25 88.7 0.0 4.8e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KII96203.1 - 8.9e-13 48.5 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF2244 PF10003.4 KII96203.1 - 0.057 12.7 0.1 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) UPF0075 PF03702.9 KII96204.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) GFO_IDH_MocA PF01408.17 KII96205.1 - 5.5e-25 88.2 0.0 1.5e-24 86.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KII96205.1 - 3.9e-07 29.8 0.0 9.9e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KII96205.1 - 0.00076 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FIST PF08495.5 KII96207.1 - 1.9e-08 33.7 0.2 4.8e-08 32.3 0.2 1.8 1 1 0 1 1 1 1 FIST N domain Tcf25 PF04910.9 KII96208.1 - 5.1e-73 246.0 0.0 6.8e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 KII96208.1 - 0.00029 20.6 0.1 0.00091 19.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 KII96208.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Rtf2 PF04641.7 KII96208.1 - 1.7 7.8 7.1 2.9 7.0 4.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger MFS_1 PF07690.11 KII96209.1 - 2.9e-20 72.3 9.0 2.9e-20 72.3 6.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KII96209.1 - 6.7e-15 55.0 1.8 6.7e-15 55.0 1.3 2.3 3 0 0 3 3 3 1 Nodulin-like DUF2569 PF10754.4 KII96209.1 - 0.0073 16.5 1.8 0.0094 16.1 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) Hyccin PF09790.4 KII96210.1 - 0.25 10.1 2.4 2.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Hyccin GBV-C_env PF12786.2 KII96210.1 - 0.52 8.7 5.5 0.8 8.0 3.8 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope Glyco_transf_22 PF03901.12 KII96211.1 - 1.4e-39 136.3 15.6 1.7e-39 136.0 10.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PPR_2 PF13041.1 KII96212.1 - 5.9e-09 35.7 0.6 1e-05 25.4 0.0 4.8 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.1 KII96212.1 - 0.026 14.7 6.4 1.2e+02 3.3 0.0 6.9 7 1 0 7 7 7 0 Pentatricopeptide repeat domain DUF4186 PF13811.1 KII96220.1 - 0.075 12.7 0.7 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4186)