# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Myc-LZ PF02344.15 KPI34264.1 - 0.16 12.1 0.7 0.16 12.1 0.7 2.4 3 0 0 3 3 3 0 Myc leucine zipper domain Mucin PF01456.17 KPI34266.1 - 2.1 8.3 12.3 2.9 7.9 12.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Fip1 PF05182.13 KPI34269.1 - 5.7e-22 77.0 1.1 9.3e-22 76.3 1.1 1.4 1 0 0 1 1 1 1 Fip1 motif Lactamase_B PF00753.27 KPI34273.1 - 4.8e-09 36.5 0.2 6.9e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI34273.1 - 5.5e-06 26.0 0.2 7.2e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KPI34273.1 - 0.056 12.9 0.0 0.07 12.6 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Mg_chelatase PF01078.21 KPI34274.1 - 0.0045 16.4 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KPI34274.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KPI34274.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KPI34274.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain EAF PF09816.9 KPI34275.1 - 3.5e-12 46.6 0.0 7.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF4927 PF16279.5 KPI34275.1 - 0.43 11.6 3.7 0.66 11.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4927) Biotin_carb_N PF00289.22 KPI34276.1 - 2e-28 99.2 0.0 2.4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain EF-hand_13 PF17958.1 KPI34276.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain Carboxyl_trans PF01039.22 KPI34277.1 - 1.3e-61 208.8 0.0 8.8e-48 163.2 0.0 2.3 2 1 0 2 2 2 2 Carboxyl transferase domain BCDHK_Adom3 PF10436.9 KPI34278.1 - 4.9e-44 150.0 0.0 7.4e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KPI34278.1 - 1.9e-11 44.4 0.0 9.1e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5615 PF18480.1 KPI34278.1 - 0.11 12.2 0.1 0.95 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) DUF1741 PF08427.10 KPI34279.1 - 5.7e-50 170.1 0.0 1.5e-46 159.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1741) Tropomodulin PF03250.14 KPI34280.1 - 0.038 14.0 0.1 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 Tropomodulin GCV_H PF01597.19 KPI34283.1 - 1e-37 128.7 0.5 1.4e-37 128.3 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KPI34283.1 - 0.067 13.0 0.8 0.19 11.6 0.3 1.9 2 1 0 2 2 2 0 Biotin-requiring enzyme CLZ PF16526.5 KPI34284.1 - 0.0031 17.8 0.3 0.0057 17.0 0.3 1.5 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BPS1 PF05633.11 KPI34284.1 - 0.023 13.7 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related NPV_P10 PF05531.12 KPI34284.1 - 0.061 13.8 1.5 0.2 12.1 0.4 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KPI34285.1 - 0.014 15.5 3.7 0.016 15.3 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_UL25 PF01499.16 KPI34285.1 - 0.044 12.3 0.4 0.052 12.1 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Peptidase_C13 PF01650.18 KPI34285.1 - 0.055 13.0 0.1 0.08 12.4 0.0 1.3 1 1 0 1 1 1 0 Peptidase C13 family PIN_8 PF18476.1 KPI34285.1 - 0.059 13.2 1.9 0.071 13.0 1.9 1.1 1 0 0 1 1 1 0 PIN like domain CHASE3 PF05227.13 KPI34285.1 - 0.095 12.6 7.4 0.17 11.8 7.4 1.5 1 1 0 1 1 1 0 CHASE3 domain Fzo_mitofusin PF04799.13 KPI34285.1 - 1.1 8.8 6.0 4 7.0 0.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region Cep57_CLD_2 PF14197.6 KPI34285.1 - 5.1 7.3 12.1 0.93 9.6 3.9 2.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 ATP-synt_E_2 PF08112.11 KPI34285.1 - 7.9 6.8 8.2 1 9.7 0.6 3.0 2 1 2 4 4 4 0 ATP synthase epsilon subunit DnaJ PF00226.31 KPI34286.1 - 2.5e-18 66.0 0.3 5.8e-18 64.8 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain EzrA PF06160.12 KPI34286.1 - 0.00049 18.4 1.2 0.00059 18.1 1.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 KPI34286.1 - 0.0018 18.6 4.5 0.01 16.1 4.5 1.9 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SRR PF07709.11 KPI34286.1 - 0.0075 16.4 0.1 13 6.7 0.1 3.2 3 0 0 3 3 3 0 Seven Residue Repeat DUF1978 PF09321.10 KPI34286.1 - 0.009 15.4 1.7 0.01 15.2 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) Jnk-SapK_ap_N PF09744.9 KPI34286.1 - 0.012 15.8 4.7 0.015 15.5 4.2 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Mer2 PF09074.10 KPI34286.1 - 0.015 15.2 0.5 0.019 14.8 0.5 1.0 1 0 0 1 1 1 0 Mer2 Tox-SHH PF15652.6 KPI34286.1 - 0.016 16.2 0.4 0.028 15.4 0.3 1.5 1 1 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature CLZ PF16526.5 KPI34286.1 - 0.017 15.4 3.3 0.036 14.4 3.2 1.7 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CdvA PF18822.1 KPI34286.1 - 0.017 14.9 3.6 0.03 14.1 3.6 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 KPI34286.1 - 0.018 15.1 0.4 0.025 14.6 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fe-S_assembly PF04384.13 KPI34286.1 - 0.023 15.3 1.0 0.041 14.5 0.8 1.6 1 1 0 1 1 1 0 Iron-sulphur cluster assembly COG5 PF10392.9 KPI34286.1 - 0.023 14.9 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF5344 PF17279.2 KPI34286.1 - 0.031 14.8 1.3 3.8 8.2 0.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF16 PF01519.16 KPI34286.1 - 0.048 14.2 0.7 0.059 13.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 TBCA PF02970.16 KPI34286.1 - 0.059 13.7 2.3 0.14 12.6 2.3 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor A TRPM_tetra PF16519.5 KPI34286.1 - 0.065 13.3 1.3 0.081 13.0 0.2 1.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF148 PF02520.17 KPI34286.1 - 0.067 13.3 2.8 0.13 12.4 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF148 SlyX PF04102.12 KPI34286.1 - 0.069 13.8 3.1 0.082 13.5 1.9 1.8 2 0 0 2 2 1 0 SlyX ApoC-I PF04691.12 KPI34286.1 - 0.084 12.8 1.2 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DASH_Dam1 PF08653.10 KPI34286.1 - 0.086 12.7 3.0 3.8 7.4 0.5 2.6 1 1 1 2 2 2 0 DASH complex subunit Dam1 KxDL PF10241.9 KPI34286.1 - 0.091 13.0 1.4 0.19 12.0 1.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF4795 PF16043.5 KPI34286.1 - 0.093 12.3 3.1 0.17 11.5 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Vac_Fusion PF02346.16 KPI34286.1 - 0.21 11.2 1.6 0.51 10.0 0.6 2.2 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF1657 PF07870.11 KPI34286.1 - 0.48 10.4 3.6 0.92 9.4 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1657) Latarcin PF10279.9 KPI34286.1 - 0.73 10.3 5.6 0.9 10.0 4.1 1.9 1 1 1 2 2 2 0 Latarcin precursor Prp19 PF08606.11 KPI34289.1 - 1.2e-30 105.3 2.5 2.3e-30 104.3 2.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KPI34289.1 - 1.6e-20 73.2 0.2 0.0015 18.8 0.0 6.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI34289.1 - 6.1e-13 49.0 7.1 0.044 14.7 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.6 KPI34289.1 - 2.3e-05 24.1 3.0 2.3e-05 24.1 3.0 1.9 1 1 1 2 2 2 2 PQQ-like domain MRP-L28 PF09812.9 KPI34290.1 - 0.0002 21.5 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Clr5 PF14420.6 KPI34291.1 - 0.00072 19.7 0.1 0.0013 18.9 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain RINGv PF12906.7 KPI34292.1 - 0.00058 19.9 5.4 0.001 19.1 5.4 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KPI34292.1 - 0.022 14.9 3.2 0.041 14.1 3.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_5 PF13719.6 KPI34292.1 - 0.11 12.2 0.3 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_2 PF13639.6 KPI34292.1 - 1.5 9.2 5.6 2.9 8.3 5.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KPI34292.1 - 3.7 7.4 5.7 8.2 6.3 5.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FMO-like PF00743.19 KPI34293.1 - 7.3e-12 44.5 0.3 1.8e-11 43.2 0.1 1.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI34293.1 - 1e-08 35.3 0.6 3.2e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34293.1 - 9.3e-07 28.4 0.0 2.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI34293.1 - 1.6e-06 28.2 0.2 0.00075 19.5 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPI34293.1 - 8.9e-05 21.8 0.1 0.0032 16.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI34293.1 - 0.0025 17.1 0.2 0.14 11.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI34293.1 - 0.0033 17.1 0.4 1.1 8.7 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPI34293.1 - 0.014 14.6 0.1 0.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Thi4 family GalKase_gal_bdg PF10509.9 KPI34294.1 - 6.7e-19 67.2 0.0 1.8e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KPI34294.1 - 6.2e-17 61.7 0.0 2.5e-16 59.8 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KPI34294.1 - 1.1e-14 54.4 1.8 1e-13 51.3 2.7 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain ATG22 PF11700.8 KPI34295.1 - 5.9e-162 539.6 11.6 6.6e-162 539.4 11.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KPI34295.1 - 0.0035 16.3 47.1 0.054 12.4 5.9 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 KPI34296.1 - 1.3e-27 96.6 37.1 1.3e-27 96.6 37.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Baculo_F PF12259.8 KPI34297.1 - 0.29 9.6 0.1 0.41 9.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein OppC_N PF12911.7 KPI34297.1 - 1.5 8.8 7.3 0.44 10.6 4.0 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Suc_Fer-like PF06999.12 KPI34298.1 - 2.3e-40 138.5 0.0 3.3e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like CPBP PF02517.16 KPI34298.1 - 2e-16 60.1 6.9 5.5e-16 58.7 6.9 1.8 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease ADH_zinc_N PF00107.26 KPI34299.1 - 2.5e-12 46.9 0.0 3.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI34299.1 - 1.3e-11 44.4 7.1 2e-11 43.7 5.6 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KPI34299.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPI34299.1 - 0.0031 16.9 0.2 0.0095 15.3 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KPI34299.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IGPD PF00475.18 KPI34300.1 - 2.8e-43 147.7 1.4 2.4e-28 99.3 0.0 2.1 1 1 1 2 2 2 2 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 KPI34300.1 - 0.0098 13.1 0.0 0.012 12.9 0.0 1.0 1 0 0 1 1 1 1 Arenavirus RNA polymerase DUF934 PF06073.12 KPI34300.1 - 0.037 13.9 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) Lactamase_B PF00753.27 KPI34301.1 - 1.2e-07 32.0 0.8 2.4e-07 30.9 0.4 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI34301.1 - 0.00014 21.5 0.1 0.00066 19.2 0.1 2.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Sugar_tr PF00083.24 KPI34302.1 - 1.1e-65 222.4 19.4 2.8e-64 217.6 19.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34302.1 - 2e-13 50.0 34.7 2.1e-07 30.2 12.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DER1 PF04511.15 KPI34303.1 - 1.1e-47 162.5 9.1 1.2e-47 162.3 9.1 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 KPI34304.1 - 2.1e-43 147.8 0.3 2.8e-43 147.4 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KPI34304.1 - 9.9e-06 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KPI34304.1 - 9.5e-05 22.7 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KPI34304.1 - 0.023 15.0 0.7 0.038 14.3 0.7 1.4 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2431 PF10354.9 KPI34305.1 - 2e-52 177.9 0.0 7.6e-52 176.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) RTC PF01137.21 KPI34306.1 - 1.5e-50 171.5 0.0 9.1e-50 168.9 0.1 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase CitMHS_2 PF16980.5 KPI34307.1 - 0.029 13.0 0.1 0.042 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative citrate transport DUF2207 PF09972.9 KPI34307.1 - 0.031 13.0 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cation_ATPase_C PF00689.21 KPI34307.1 - 0.044 13.5 0.8 0.071 12.8 0.8 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2407_C PF13373.6 KPI34307.1 - 0.1 12.8 0.0 7 6.8 0.0 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain stn_TNFRSF12A PF12191.8 KPI34307.1 - 0.12 12.7 0.0 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3481 PF11980.8 KPI34307.1 - 0.15 11.8 0.1 0.73 9.6 0.0 2.1 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein DUF3072 PF11272.8 KPI34308.1 - 3.2e-34 116.6 6.5 3.6e-20 71.6 0.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3072) Metallophos PF00149.28 KPI34309.1 - 8.2e-12 46.0 1.2 1.3e-11 45.4 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI34309.1 - 1.7e-10 41.4 0.1 1.9e-09 37.9 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 KPI34310.1 - 2.2e-13 49.8 0.0 4.8e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI34310.1 - 0.026 14.5 0.2 0.073 13.1 0.1 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KPI34310.1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI-anchored PF10342.9 KPI34311.1 - 3.1e-19 69.5 2.0 3.4e-19 69.4 0.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.18 KPI34313.1 - 1.3e-17 63.7 0.1 2.4e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI34313.1 - 2.4e-07 30.8 16.0 4.1e-07 30.0 16.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 KPI34313.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 HalX domain FlxA PF14282.6 KPI34313.1 - 0.43 10.6 4.5 0.91 9.5 4.5 1.4 1 0 0 1 1 1 0 FlxA-like protein FA_hydroxylase PF04116.13 KPI34314.1 - 1.5e-10 41.5 20.1 1.7e-10 41.3 20.1 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KPI34314.1 - 0.0011 19.2 0.4 0.0019 18.5 0.1 1.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region CK_II_beta PF01214.18 KPI34315.1 - 9.1e-75 250.5 0.0 1.3e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 KPI34315.1 - 0.16 12.2 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Spt5_N PF11942.8 KPI34315.1 - 2 9.5 9.2 0.25 12.3 3.8 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.11 KPI34315.1 - 3 5.8 10.2 13 3.7 9.3 1.8 1 1 1 2 2 2 0 Sporozoite P67 surface antigen E1_dh PF00676.20 KPI34316.1 - 2.7e-112 374.6 0.3 3.4e-112 374.3 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KPI34316.1 - 0.00032 20.0 0.1 0.00054 19.3 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KPI34316.1 - 0.018 14.8 0.7 0.039 13.7 0.7 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.25 KPI34317.1 - 4.3e-75 252.5 0.0 5.4e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI34317.1 - 2.3e-36 125.4 0.0 3.2e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI34317.1 - 6.3e-05 22.1 0.1 0.22 10.4 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KPI34317.1 - 0.0066 16.4 0.4 0.02 14.8 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KPI34317.1 - 0.0076 15.6 0.2 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPI34317.1 - 0.15 11.4 0.0 0.35 10.1 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Atrophin-1 PF03154.15 KPI34317.1 - 0.53 8.5 5.5 0.76 8.0 5.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family Clat_adaptor_s PF01217.20 KPI34318.1 - 9.9e-09 35.3 0.0 0.0058 16.6 0.1 2.2 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Peptidase_S80 PF07230.11 KPI34318.1 - 0.069 11.4 0.0 0.095 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) zf-RING_2 PF13639.6 KPI34319.1 - 1.3e-08 35.0 2.0 2e-08 34.4 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI34319.1 - 2e-05 24.5 2.1 3.4e-05 23.8 2.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KPI34319.1 - 3.9e-05 23.9 2.9 0.00076 19.7 2.8 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI34319.1 - 0.0011 19.0 0.2 0.0017 18.3 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KPI34319.1 - 0.01 15.6 2.4 0.019 14.7 2.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPI34319.1 - 0.011 15.6 3.2 0.037 13.9 3.2 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fucose_iso_N1 PF07881.12 KPI34319.1 - 0.039 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain zf-C3HC4 PF00097.25 KPI34319.1 - 0.22 11.4 1.2 0.41 10.6 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.6 KPI34320.1 - 3.5e-88 296.3 1.6 5.5e-88 295.6 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KPI34320.1 - 8.5e-13 49.2 0.0 2.6e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 KPI34320.1 - 9.4e-05 22.0 0.0 0.0002 21.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MARVEL PF01284.23 KPI34321.1 - 5.6 7.0 14.3 8.7 6.4 14.3 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF2070 PF09843.9 KPI34321.1 - 6.1 5.0 6.5 7.5 4.7 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Methyltransf_25 PF13649.6 KPI34322.1 - 0.095 13.4 0.0 0.26 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NACHT_sigma PF17106.5 KPI34322.1 - 0.35 11.0 1.5 0.69 10.1 1.5 1.4 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases Mito_carr PF00153.27 KPI34324.1 - 1.2e-56 188.6 1.4 5.8e-20 71.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 KPI34324.1 - 0.086 12.9 7.0 0.86 9.7 0.0 3.6 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif Ras PF00071.22 KPI34325.1 - 0.086 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Ras family Cpn60_TCP1 PF00118.24 KPI34326.1 - 1.2e-125 419.9 2.8 1.4e-125 419.7 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4621 PF15414.6 KPI34326.1 - 0.021 13.8 0.5 0.046 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4621) NST1 PF13945.6 KPI34327.1 - 1.8e-56 191.3 3.9 1.8e-56 191.3 3.9 4.6 3 1 1 4 4 4 1 Salt tolerance down-regulator Helicase_C PF00271.31 KPI34328.1 - 1.1e-31 109.4 0.3 1.1e-30 106.2 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI34328.1 - 1.3e-22 80.4 0.0 2.3e-18 66.6 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KPI34328.1 - 0.00023 20.5 0.1 0.00037 19.8 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Lactamase_B PF00753.27 KPI34329.1 - 0.043 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Ras PF00071.22 KPI34330.1 - 7.3e-50 168.7 0.0 8.7e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI34330.1 - 2.9e-22 79.1 0.0 4.1e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI34330.1 - 8.3e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPI34330.1 - 0.013 14.9 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPI34330.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KPI34330.1 - 0.11 12.3 0.0 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADH_zinc_N PF00107.26 KPI34330.1 - 0.12 12.3 0.0 9.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MMR_HSR1 PF01926.23 KPI34330.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cpn60_TCP1 PF00118.24 KPI34331.1 - 2.7e-23 82.4 0.0 3e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NmrA PF05368.13 KPI34333.1 - 6.3e-08 32.5 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI34333.1 - 3.9e-07 30.1 0.1 6.4e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding UPF0731 PF14982.6 KPI34333.1 - 0.18 12.0 0.2 0.35 11.1 0.2 1.4 1 0 0 1 1 1 0 UPF0731 family Peptidase_M14 PF00246.24 KPI34334.1 - 1.5e-71 241.6 0.0 1.9e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KPI34334.1 - 0.074 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Aft1_HRA PF11786.8 KPI34335.1 - 2.7e-19 69.3 8.3 2.7e-19 69.3 8.3 2.7 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 KPI34335.1 - 6.4e-17 62.5 10.0 6.4e-17 62.5 10.0 4.4 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 KPI34335.1 - 9.3e-13 48.4 11.7 1.4e-11 44.7 10.0 3.4 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KPI34335.1 - 1.6e-11 44.1 7.2 2.6e-11 43.4 7.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI34335.1 - 4.8e-06 26.6 6.4 1.2e-05 25.2 6.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPI34335.1 - 0.0026 18.2 4.8 0.0026 18.2 4.8 2.7 4 0 0 4 4 4 1 bZIP Maf transcription factor DivIC PF04977.15 KPI34335.1 - 0.25 11.1 1.4 0.62 9.9 1.4 1.6 1 0 0 1 1 1 0 Septum formation initiator TCTP PF00838.17 KPI34336.1 - 3.1e-53 180.5 0.3 3.5e-53 180.3 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein p450 PF00067.22 KPI34337.1 - 2.9e-23 82.4 0.0 3.3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KPI34338.1 - 1.2e-65 222.1 0.0 1.6e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ARID PF01388.21 KPI34340.1 - 2.8e-15 56.8 0.0 8.5e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.29 KPI34342.1 - 5.4e-45 153.1 0.8 1.7e-44 151.4 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPI34342.1 - 3.5e-10 39.7 0.1 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KPI34342.1 - 9e-09 35.5 0.1 3.2e-08 33.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPI34342.1 - 7.4e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KPI34342.1 - 2e-07 31.6 0.4 3.9e-05 24.1 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KPI34342.1 - 4.5e-06 26.0 0.0 8.5e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KPI34342.1 - 4.1e-05 23.9 1.1 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KPI34342.1 - 0.00031 20.5 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KPI34342.1 - 0.00037 20.3 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KPI34342.1 - 0.0007 19.2 0.0 0.0072 15.9 0.1 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KPI34342.1 - 0.00091 19.8 0.0 0.0029 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KPI34342.1 - 0.00094 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KPI34342.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KPI34342.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KPI34342.1 - 0.0016 18.4 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KPI34342.1 - 0.0023 17.8 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 KPI34342.1 - 0.0027 17.7 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPI34342.1 - 0.0057 16.4 0.1 0.014 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KPI34342.1 - 0.0068 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KPI34342.1 - 0.0071 15.8 0.1 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KPI34342.1 - 0.0082 16.1 0.7 0.11 12.4 0.0 2.8 4 0 0 4 4 2 1 NACHT domain AAA_33 PF13671.6 KPI34342.1 - 0.0092 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPI34342.1 - 0.01 15.6 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 KPI34342.1 - 0.011 15.2 0.0 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KPI34342.1 - 0.021 14.6 0.2 0.053 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KPI34342.1 - 0.041 13.2 1.2 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC ATPase_2 PF01637.18 KPI34342.1 - 0.043 13.7 1.1 0.32 10.9 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KPI34342.1 - 0.054 13.3 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KPI34342.1 - 0.073 12.8 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 KPI34342.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 KPI34342.1 - 0.092 12.3 1.4 0.27 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain Viral_Hsp90 PF03225.14 KPI34342.1 - 0.11 11.0 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_19 PF13245.6 KPI34342.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KPI34342.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KPI34342.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KPI34342.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KPI34343.1 - 6e-12 45.8 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KPI34343.1 - 8.1e-07 28.5 0.0 2.5e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 KPI34343.1 - 6.9e-06 26.5 0.0 6e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI34343.1 - 4.1e-05 23.9 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KPI34343.1 - 0.0001 22.8 0.0 0.0004 20.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KPI34343.1 - 0.0023 17.9 0.1 0.0056 16.7 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KPI34343.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KPI34343.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KPI34343.1 - 0.065 12.9 0.0 0.28 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KPI34343.1 - 0.07 13.0 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein NTPase_1 PF03266.15 KPI34343.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Pkinase PF00069.25 KPI34344.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 3.0 4 0 0 4 4 4 1 Protein kinase domain PaaX_C PF08223.11 KPI34344.1 - 0.066 13.5 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain FA_hydroxylase PF04116.13 KPI34345.1 - 6.7e-23 81.5 13.1 6.7e-23 81.5 13.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX4 PF02936.14 KPI34346.1 - 2.6e-49 166.8 0.4 3.3e-49 166.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UPF0253 PF06786.12 KPI34347.1 - 0.083 13.2 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Tantalus PF15386.6 KPI34347.1 - 0.19 11.9 0.5 8.8 6.5 0.2 2.4 2 0 0 2 2 2 0 Drosophila Tantalus-like GST_C_6 PF17171.4 KPI34348.1 - 1.9e-17 62.8 0.1 3.5e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KPI34348.1 - 7.3e-17 61.9 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KPI34348.1 - 1.5e-11 44.7 0.1 2.7e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KPI34348.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.8 1 1 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KPI34348.1 - 0.073 13.1 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP-synt_ab PF00006.25 KPI34349.1 - 2e-40 138.8 0.5 3.9e-22 78.9 0.0 2.6 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KPI34349.1 - 8.4e-24 83.9 0.5 3.7e-23 81.8 0.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KPI34349.1 - 0.013 14.7 0.5 0.077 12.2 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KPI34349.1 - 0.014 15.4 0.2 0.027 14.4 0.1 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 KPI34349.1 - 0.023 15.0 0.5 0.45 10.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KPI34349.1 - 0.032 13.6 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 KPI34349.1 - 0.044 13.7 0.2 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KPI34349.1 - 0.085 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 KPI34349.1 - 0.11 12.3 0.8 0.52 10.2 0.8 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 KPI34349.1 - 0.22 11.4 0.2 0.78 9.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FAD_binding_1 PF00667.20 KPI34350.1 - 5.6e-30 104.6 0.0 8.2e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPI34350.1 - 1.7e-22 80.2 0.1 5.1e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KPI34350.1 - 8.2e-07 29.6 0.0 0.0001 22.9 0.0 2.7 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KPI34350.1 - 0.00011 22.5 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain AMP-binding PF00501.28 KPI34352.1 - 1.1e-84 284.5 0.0 1.3e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI34352.1 - 3.2e-14 53.7 0.9 9.2e-14 52.2 0.9 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cofilin_ADF PF00241.20 KPI34353.1 - 1.5e-27 95.8 0.1 2.6e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Utp21 PF04192.12 KPI34353.1 - 0.17 11.3 0.1 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Alpha-amylase PF00128.24 KPI34356.1 - 1.6e-102 343.5 0.2 1.9e-81 274.3 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPI34356.1 - 0.0013 18.0 0.0 0.0031 16.7 0.0 1.6 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KPI34356.1 - 0.0029 17.7 0.0 0.0075 16.4 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain VTC PF09359.10 KPI34357.1 - 4.2e-86 288.8 1.2 4.2e-86 288.8 1.2 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 KPI34357.1 - 2.1e-09 37.8 13.7 6.7e-05 23.0 5.7 2.7 1 1 1 2 2 2 2 SPX domain NPV_P10 PF05531.12 KPI34357.1 - 0.0027 18.1 2.4 0.28 11.7 0.0 2.8 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Herpes_UL25 PF01499.16 KPI34357.1 - 0.021 13.3 0.3 0.036 12.6 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4763 PF15960.5 KPI34357.1 - 0.1 11.9 3.1 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) KxDL PF10241.9 KPI34357.1 - 0.23 11.8 5.0 0.23 11.8 2.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein WDCP PF15390.6 KPI34357.1 - 0.23 9.8 6.2 0.19 10.0 2.0 2.0 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF948 PF06103.11 KPI34357.1 - 0.93 9.8 7.3 21 5.4 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1690 PF07956.11 KPI34357.1 - 1.1 9.7 8.9 1.1 9.6 4.1 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF1664 PF07889.12 KPI34357.1 - 2.1 8.4 7.9 8.9 6.4 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phostensin_N PF13916.6 KPI34357.1 - 5.6 7.4 7.1 15 6.0 0.0 3.8 4 1 0 4 4 3 0 PP1-regulatory protein, Phostensin N-terminal BLOC1_2 PF10046.9 KPI34357.1 - 6.5 7.1 9.1 6.1 7.2 3.7 2.9 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KPI34357.1 - 6.6 6.9 8.8 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NUDIX PF00293.28 KPI34358.1 - 2.5e-12 47.0 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NMO PF03060.15 KPI34359.1 - 5.8e-35 121.3 1.2 5.6e-27 95.0 0.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KPI34359.1 - 1.5e-08 34.0 0.0 3.3e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPI34359.1 - 0.00018 20.6 5.6 0.00029 20.0 4.5 1.7 1 1 1 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPI34359.1 - 0.005 16.0 0.9 0.0077 15.4 0.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Cupin_2 PF07883.11 KPI34360.1 - 2e-07 30.6 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MFS_1 PF07690.16 KPI34361.1 - 1.2e-34 119.9 40.3 1.2e-34 119.9 40.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI34361.1 - 2.1e-08 33.9 10.4 2.1e-08 33.9 10.4 2.3 1 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Abhydrolase_3 PF07859.13 KPI34362.1 - 5e-41 140.9 0.0 6.6e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI34362.1 - 0.003 18.2 0.3 0.003 18.2 0.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 KPI34362.1 - 0.0037 16.2 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Gpr1_Fun34_YaaH PF01184.19 KPI34363.1 - 1.1e-26 93.7 15.1 1.5e-26 93.3 15.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Lactamase_B_2 PF12706.7 KPI34364.1 - 0.093 12.2 0.2 0.28 10.7 0.1 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain EHN PF06441.12 KPI34365.1 - 7e-29 100.4 0.1 1.2e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI34365.1 - 2.7e-12 46.9 0.0 5.5e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI34365.1 - 0.00011 22.9 1.0 0.0002 22.1 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF5577 PF17740.1 KPI34365.1 - 0.25 11.0 0.0 0.36 10.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5577) BAAT_C PF08840.11 KPI34366.1 - 1.7e-05 24.9 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 KPI34366.1 - 0.00044 20.2 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF1100 PF06500.11 KPI34366.1 - 0.00059 18.7 0.1 0.11 11.3 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 KPI34366.1 - 0.0016 18.1 0.1 0.0025 17.4 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KPI34366.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPI34366.1 - 0.02 15.5 0.2 0.067 13.8 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 KPI34366.1 - 0.062 12.0 0.0 0.094 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.18 KPI34367.1 - 7.4e-09 35.6 8.3 1.4e-08 34.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytomega_UL84 PF06284.11 KPI34367.1 - 0.053 12.0 0.0 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FMO-like PF00743.19 KPI34369.1 - 3.4e-18 65.4 0.2 2.8e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI34369.1 - 9e-13 48.3 0.0 2.4e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34369.1 - 1.4e-07 31.1 0.0 0.00019 20.8 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI34369.1 - 1.6e-07 30.8 0.0 0.00024 20.4 0.0 3.2 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI34369.1 - 1.9e-05 24.1 0.0 0.0076 15.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI34369.1 - 0.0057 16.7 0.1 0.097 12.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KPI34369.1 - 0.0084 15.7 0.1 0.27 10.8 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI34369.1 - 0.013 14.8 0.0 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KPI34369.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.18 KPI34370.1 - 3.3e-06 27.1 8.3 5.7e-06 26.3 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI34370.1 - 0.00051 19.2 0.0 0.00083 18.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ZapB PF06005.12 KPI34371.1 - 0.00073 19.9 2.5 0.0013 19.2 2.5 1.4 1 0 0 1 1 1 1 Cell division protein ZapB SKA2 PF16740.5 KPI34371.1 - 0.0086 15.9 0.4 0.013 15.3 0.4 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 YabA PF06156.13 KPI34371.1 - 0.065 13.9 0.5 0.13 12.9 0.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 KPI34371.1 - 0.066 13.5 2.5 0.11 12.8 2.5 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family Ax_dynein_light PF10211.9 KPI34371.1 - 0.071 13.1 2.2 0.085 12.8 2.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.22 KPI34371.1 - 0.13 12.5 4.6 0.21 11.8 2.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ApoO PF09769.9 KPI34371.1 - 0.24 11.4 1.1 0.33 10.9 1.0 1.3 1 1 0 1 1 1 0 Apolipoprotein O CP12 PF02672.15 KPI34371.1 - 0.88 10.4 6.6 2.7 8.8 0.1 2.8 1 1 1 2 2 2 0 CP12 domain ADH_N PF08240.12 KPI34372.1 - 5.8e-11 42.2 0.7 6.1e-09 35.7 0.2 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI34372.1 - 9.3e-07 28.9 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI34372.1 - 2.8e-06 28.4 0.0 4.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nup54 PF13874.6 KPI34373.1 - 0.95 9.6 12.9 0.3 11.2 8.4 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 KPI34373.1 - 3.7 7.6 8.8 14 5.7 0.0 3.4 2 2 1 3 3 3 0 Laminin Domain II STAT_alpha PF01017.20 KPI34373.1 - 4 7.3 8.7 2.9 7.8 4.6 2.4 3 0 0 3 3 3 0 STAT protein, all-alpha domain COesterase PF00135.28 KPI34374.1 - 3.7e-51 174.5 0.0 5.6e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI34374.1 - 0.00094 19.1 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Epimerase PF01370.21 KPI34375.1 - 5.7e-08 32.5 0.0 3.3e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI34375.1 - 0.00014 21.0 0.0 0.0014 17.7 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPI34375.1 - 0.00058 19.1 0.0 0.0033 16.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KPI34376.1 - 3.2e-27 95.3 1.7 5.4e-27 94.5 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34376.1 - 1.4e-16 60.7 2.0 2.8e-16 59.8 2.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPI34376.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 KPI34376.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans_2 PF11951.8 KPI34378.1 - 0.0044 15.9 0.1 0.043 12.6 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain PMT PF02366.18 KPI34379.1 - 5e-70 235.9 9.9 5e-70 235.9 9.9 2.0 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 KPI34379.1 - 5.2e-47 160.1 0.3 9.3e-47 159.3 0.3 1.4 1 0 0 1 1 1 1 MIR domain PMT_4TMC PF16192.5 KPI34379.1 - 2.8e-37 128.2 5.5 6.1e-26 91.2 0.1 2.6 2 0 0 2 2 2 2 C-terminal four TMM region of protein-O-mannosyltransferase Fungal_trans PF04082.18 KPI34380.1 - 5.6e-07 28.9 0.1 9.5e-07 28.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOG2 PF10428.9 KPI34382.1 - 4.2 6.4 30.0 5.8 6.0 30.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Nrap_D5 PF17406.2 KPI34383.1 - 5.8e-50 169.2 1.3 2.2e-49 167.4 0.8 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 KPI34383.1 - 1.7e-38 132.2 0.0 3.8e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 KPI34383.1 - 5.9e-36 123.8 0.0 1.3e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KPI34383.1 - 2.3e-33 115.1 0.0 1.6e-30 105.9 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 KPI34383.1 - 2.2e-29 102.4 0.0 3.9e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 KPI34383.1 - 1.6e-28 99.7 0.0 2.8e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 SUR7 PF06687.12 KPI34384.1 - 2.9e-26 92.4 6.4 3.9e-26 92.0 6.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family NAD_binding_5 PF07994.12 KPI34384.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase S_4TM PF18159.1 KPI34384.1 - 0.28 10.4 0.5 0.59 9.4 0.3 1.5 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain Aldo_ket_red PF00248.21 KPI34385.1 - 3.1e-40 138.2 0.1 3e-31 108.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.16 KPI34386.1 - 9.3e-30 103.7 33.5 1.3e-29 103.3 33.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI34386.1 - 6.7e-05 22.3 9.2 6.7e-05 22.3 9.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB GRA6 PF05084.13 KPI34386.1 - 0.36 10.8 2.1 4 7.3 0.4 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) DAD PF02109.16 KPI34386.1 - 2.7 8.3 8.6 0.39 11.0 0.1 3.3 3 1 1 4 4 4 0 DAD family PRP21_like_P PF12230.8 KPI34387.1 - 7.8e-54 182.8 5.7 2.8e-53 181.0 5.7 1.8 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KPI34387.1 - 1.9e-36 123.8 0.8 5.8e-19 67.8 0.0 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KPI34387.1 - 0.0012 18.4 0.1 0.0031 17.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf_C2HC_14 PF18574.1 KPI34387.1 - 0.033 14.0 0.1 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 C2HC Zing finger domain FYDLN_acid PF09538.10 KPI34387.1 - 3.6 8.3 7.1 1.1 10.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) adh_short PF00106.25 KPI34388.1 - 5.9e-16 58.5 0.0 3.6e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI34388.1 - 1.8e-08 34.5 0.0 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI34388.1 - 2.3e-07 30.6 0.0 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ABC1 PF03109.16 KPI34389.1 - 2.8e-22 79.1 0.0 5.8e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KPI34389.1 - 0.067 13.1 0.1 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family YpsA PF06908.11 KPI34389.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 YspA SLOG family Aminotran_3 PF00202.21 KPI34390.1 - 3.5e-44 151.1 0.0 1.3e-42 145.9 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KPI34390.1 - 0.0032 16.8 0.1 0.0058 16.0 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KPI34392.1 - 9.6e-33 113.2 0.0 1.3e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme EB1 PF03271.17 KPI34393.1 - 5.2e-17 61.8 1.1 1.1e-16 60.8 1.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KPI34393.1 - 3.7e-07 30.3 0.2 1e-06 28.9 0.1 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 KPI34393.1 - 0.053 13.7 0.1 0.085 13.0 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Syja_N PF02383.18 KPI34393.1 - 0.099 11.9 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain COesterase PF00135.28 KPI34395.1 - 5.3e-94 315.9 0.0 6e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI34395.1 - 2.9e-07 30.6 1.5 2.9e-06 27.3 1.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Solute_trans_a PF03619.16 KPI34396.1 - 3e-41 141.7 18.5 3.6e-41 141.5 18.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4492 PF14899.6 KPI34396.1 - 0.027 14.4 0.8 0.092 12.7 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) PhoLip_ATPase_C PF16212.5 KPI34396.1 - 0.092 12.5 13.5 0.48 10.1 5.7 2.6 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal GPR_Gpa2_C PF11970.8 KPI34396.1 - 0.98 9.5 12.4 0.56 10.3 2.4 3.0 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Epimerase PF01370.21 KPI34397.1 - 6.3e-16 58.6 0.0 8.1e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPI34397.1 - 4.8e-07 29.6 0.1 0.0044 16.6 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KPI34397.1 - 6.2e-07 29.5 0.0 1.2e-06 28.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KPI34397.1 - 0.00012 21.6 0.0 0.00042 19.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF4974 PF16344.5 KPI34397.1 - 0.008 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) adh_short PF00106.25 KPI34397.1 - 0.031 13.7 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KPI34397.1 - 0.032 13.4 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro2_C5 PF18565.1 KPI34398.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 Ribosomal_L5_C PF00673.21 KPI34399.1 - 5.5e-31 106.6 0.0 9.5e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KPI34399.1 - 1.3e-06 28.7 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 DASH_Dad1 PF08649.10 KPI34400.1 - 7.3e-20 70.9 0.2 8.7e-20 70.7 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 TRI12 PF06609.13 KPI34401.1 - 6e-55 186.8 26.4 2.6e-53 181.4 26.4 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI34401.1 - 4.7e-22 78.4 46.8 1.3e-19 70.3 45.4 3.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3522 PF12036.8 KPI34401.1 - 0.016 15.5 2.1 0.016 15.5 2.1 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3522) DUF3040 PF11239.8 KPI34401.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Complex1_LYR PF05347.15 KPI34402.1 - 3.8e-08 33.3 0.3 6.9e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPI34402.1 - 3.1e-06 27.8 0.3 5.3e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DUF1770 PF08589.10 KPI34403.1 - 1.7e-21 77.0 4.4 3.1e-21 76.2 4.4 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Sugar_tr PF00083.24 KPI34404.1 - 1.5e-78 264.7 19.3 3e-76 257.1 19.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34404.1 - 3.2e-21 75.7 21.2 3.1e-20 72.4 20.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI34404.1 - 3.7e-09 35.6 1.8 9.6e-09 34.2 0.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KPI34404.1 - 7.6e-08 31.3 0.3 7.6e-08 31.3 0.3 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein YrhK PF14145.6 KPI34404.1 - 0.023 14.6 3.1 0.046 13.6 1.3 2.6 1 1 1 2 2 2 0 YrhK-like protein Pro_CA PF00484.19 KPI34405.1 - 0.0013 19.1 0.0 0.0017 18.6 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase Lactamase_B PF00753.27 KPI34406.1 - 1.5e-09 38.2 2.8 2.6e-09 37.4 2.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI34406.1 - 0.0014 18.2 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI34406.1 - 0.004 17.1 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RNA_pol_L_2 PF13656.6 KPI34407.1 - 8.2e-27 92.8 0.0 1e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KPI34407.1 - 9.2e-08 31.4 0.0 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Aminotran_4 PF01063.19 KPI34408.1 - 7.6e-26 91.3 0.0 8.7e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Ras PF00071.22 KPI34409.1 - 4.4e-37 127.2 0.0 6.4e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI34409.1 - 1e-11 45.1 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI34409.1 - 0.019 14.5 0.0 0.045 13.2 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Myc_target_1 PF15179.6 KPI34409.1 - 0.033 14.1 2.0 0.048 13.6 2.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 Fungal_trans PF04082.18 KPI34410.1 - 3.9e-15 55.6 0.1 6e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI34410.1 - 0.0069 16.5 5.7 0.02 15.0 5.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1_DNA_bind PF10373.9 KPI34411.1 - 1.3e-35 123.2 0.2 2.9e-35 122.1 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KPI34411.1 - 1.1e-19 71.4 0.8 1.1e-19 71.4 0.8 2.5 2 0 0 2 2 2 1 Telomerase activating protein Est1 FH2 PF02181.23 KPI34411.1 - 0.13 11.3 2.1 0.18 10.9 1.1 1.7 2 0 0 2 2 2 0 Formin Homology 2 Domain EHN PF06441.12 KPI34412.1 - 3.7e-32 110.9 0.1 6.7e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI34412.1 - 9.1e-14 51.7 0.0 1.4e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI34412.1 - 0.00044 20.9 0.8 0.00081 20.0 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.18 KPI34413.1 - 1.3e-16 60.5 0.1 2.1e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 KPI34414.1 - 2.1e-15 56.2 0.0 4.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI34414.1 - 1.4e-10 41.2 0.0 3.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34414.1 - 1.5e-08 34.3 0.0 8.5e-08 31.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI34414.1 - 3.3e-06 26.5 0.0 4.6e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI34414.1 - 2e-05 23.9 0.0 0.00036 19.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI34414.1 - 0.0039 17.2 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KPI34414.1 - 0.0051 16.1 0.0 0.22 10.8 0.0 2.6 3 0 0 3 3 3 1 Thi4 family PHO4 PF01384.20 KPI34415.1 - 2.9e-100 335.6 18.0 3.4e-100 335.4 18.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family ABC2_membrane PF01061.24 KPI34416.1 - 7.5e-74 247.7 56.8 1.6e-37 129.0 21.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KPI34416.1 - 6e-40 136.9 0.0 9.2e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPI34416.1 - 5.1e-18 64.8 0.2 7.3e-17 61.1 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPI34416.1 - 4.1e-12 46.5 0.2 1e-11 45.3 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 KPI34416.1 - 2.3e-06 27.7 0.0 0.06 13.1 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KPI34416.1 - 1.9e-05 25.1 0.2 0.085 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KPI34416.1 - 4.7e-05 23.0 0.1 0.0041 16.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPI34416.1 - 7.4e-05 22.4 0.8 0.032 14.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KPI34416.1 - 0.00017 21.8 0.1 0.17 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI34416.1 - 0.00043 20.2 0.2 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KPI34416.1 - 0.0027 16.9 18.8 0.0027 16.9 18.8 2.9 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_18 PF13238.6 KPI34416.1 - 0.0049 17.4 0.0 0.23 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KPI34416.1 - 0.0072 15.3 0.2 0.98 8.3 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KPI34416.1 - 0.0077 16.4 0.1 0.74 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KPI34416.1 - 0.0079 15.7 0.0 0.04 13.3 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KPI34416.1 - 0.0098 15.8 1.2 3.5 7.5 0.4 2.9 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KPI34416.1 - 0.011 15.5 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPI34416.1 - 0.011 16.0 1.3 4.3 7.6 0.5 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KPI34416.1 - 0.018 14.7 3.4 0.75 9.4 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KPI34416.1 - 0.034 14.6 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPI34416.1 - 0.059 12.6 0.1 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 KPI34416.1 - 0.088 12.7 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 KPI34416.1 - 0.095 12.4 0.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KPI34416.1 - 0.1 13.1 0.1 16 5.9 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KPI34416.1 - 0.16 11.6 0.1 5.3 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KPI34416.1 - 1 9.0 2.3 1.9 8.1 0.6 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ADH_N_2 PF16884.5 KPI34417.1 - 3.2e-30 104.2 0.0 5.4e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KPI34417.1 - 5.3e-09 36.1 1.0 2.8e-06 27.3 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase adh_short PF00106.25 KPI34418.1 - 3.5e-34 118.0 0.1 4e-32 111.3 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34418.1 - 6.2e-22 78.3 0.2 8.5e-21 74.6 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF2298 PF10060.9 KPI34418.1 - 0.079 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Kelch_4 PF13418.6 KPI34418.1 - 0.11 12.6 0.2 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Fungal_trans_2 PF11951.8 KPI34419.1 - 8.3e-05 21.6 0.3 0.00045 19.1 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KPI34420.1 - 2e-21 76.7 0.0 3.2e-21 76.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI34420.1 - 6.6e-10 39.1 0.4 0.00042 20.0 0.4 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI34420.1 - 4.2e-08 32.8 0.1 0.00028 20.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI34420.1 - 6.8e-05 23.3 0.1 0.00025 21.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI34420.1 - 0.0015 18.7 0.1 0.0042 17.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI34420.1 - 0.0035 16.5 0.1 0.0068 15.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 KPI34420.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KPI34420.1 - 0.033 13.5 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KPI34420.1 - 0.084 11.9 0.1 0.89 8.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Rossmann-like PF10727.9 KPI34420.1 - 0.086 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34420.1 - 0.11 11.8 0.0 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KPI34420.1 - 0.18 12.3 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Trp_halogenase PF04820.14 KPI34420.1 - 0.19 10.6 0.5 1.7 7.4 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase adh_short_C2 PF13561.6 KPI34421.1 - 4.4e-60 203.1 1.0 5.3e-60 202.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI34421.1 - 4.9e-51 173.0 0.2 6e-51 172.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI34421.1 - 2.4e-13 50.4 0.1 3.6e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI34421.1 - 0.00023 20.7 0.1 0.0013 18.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KPI34421.1 - 0.01 15.2 0.0 0.056 12.8 0.0 2.0 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KPI34421.1 - 0.023 14.0 0.9 0.058 12.7 0.1 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 KPI34421.1 - 0.033 14.2 0.6 0.1 12.7 0.4 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT_7 PF13840.6 KPI34421.1 - 0.036 13.8 0.3 7.1 6.5 0.0 3.0 2 1 0 2 2 2 0 ACT domain 3HCDH_N PF02737.18 KPI34421.1 - 0.11 12.3 1.4 0.2 11.5 0.5 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KPI34422.1 - 1.2e-75 255.1 0.0 1.5e-75 254.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KPI34422.1 - 2e-24 86.4 0.0 3.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPI34422.1 - 8.4e-24 84.4 0.0 1.6e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPI34422.1 - 5.8e-13 49.4 0.0 4.5e-12 46.6 0.0 2.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain PAP2 PF01569.21 KPI34423.1 - 7.2e-17 61.4 4.8 7.2e-17 61.4 4.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KPI34423.1 - 0.0028 17.4 6.7 0.0082 15.9 6.7 1.9 1 1 0 1 1 1 1 PAP2 superfamily Sugar_tr PF00083.24 KPI34424.1 - 9.8e-94 314.7 16.9 1.2e-93 314.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34424.1 - 1e-21 77.3 38.0 2.8e-20 72.6 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI34424.1 - 0.00025 20.4 8.2 0.00025 20.4 8.2 1.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KPI34424.1 - 0.00058 18.4 4.7 0.00058 18.4 4.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KPI34424.1 - 0.2 12.2 4.4 0.081 13.5 0.9 2.2 2 0 0 2 2 2 0 Phage holin family 2 Fungal_trans PF04082.18 KPI34425.1 - 4.9e-09 35.6 0.2 7.6e-09 35.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF383 PF04063.14 KPI34425.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF383) adh_short PF00106.25 KPI34427.1 - 2.1e-18 66.5 0.0 7.1e-15 55.0 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34427.1 - 3.3e-15 56.3 0.0 1.2e-12 47.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI34427.1 - 0.0057 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Motile_Sperm PF00635.26 KPI34428.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Gly_radical PF01228.21 KPI34428.1 - 0.081 13.5 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycine radical DUF4119 PF13494.6 KPI34428.1 - 0.098 12.8 0.1 0.31 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF4611 PF15387.6 KPI34428.1 - 0.14 12.4 3.9 0.66 10.2 3.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) 2OG-FeII_Oxy_2 PF13532.6 KPI34429.1 - 1.6e-11 44.8 0.0 2.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TraQ PF09679.10 KPI34430.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) CDC45 PF02724.14 KPI34430.1 - 2.6 6.2 26.0 0.18 10.1 8.2 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4604 PF15377.6 KPI34430.1 - 8.8 6.7 28.9 0.87 10.0 9.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Methyltransf_23 PF13489.6 KPI34431.1 - 0.005 16.7 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI34431.1 - 0.027 15.1 0.0 0.042 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pmp3 PF01679.17 KPI34432.1 - 5e-12 45.8 9.5 7e-12 45.3 9.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sua5_yciO_yrdC PF01300.18 KPI34433.1 - 6.2e-46 156.1 0.0 1.1e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KPI34433.1 - 2.1e-20 73.7 0.0 3.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding PS_Dcarbxylase PF02666.15 KPI34435.1 - 4e-49 166.9 0.0 6e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_hydro_3_C PF01915.22 KPI34437.1 - 1.3e-55 188.5 0.0 2.4e-55 187.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI34437.1 - 1.3e-41 143.0 0.0 2.1e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI34437.1 - 3.6e-21 75.1 0.4 7.4e-21 74.0 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPI34437.1 - 6.1e-15 55.3 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 KPI34437.1 - 0.04 14.3 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FMO-like PF00743.19 KPI34438.1 - 9.2e-20 70.5 0.1 3.5e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI34438.1 - 1.9e-12 47.0 0.5 7.1e-11 41.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI34438.1 - 3.1e-11 43.1 0.0 1.1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI34438.1 - 8.6e-11 41.9 0.0 2.4e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34438.1 - 6.5e-10 38.7 0.0 1.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI34438.1 - 7.6e-10 38.9 0.1 0.00046 19.9 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI34438.1 - 4.3e-08 32.3 0.2 0.085 11.5 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein NAD_binding_9 PF13454.6 KPI34438.1 - 4.7e-05 23.4 0.0 0.0065 16.5 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KPI34438.1 - 0.00017 22.1 0.1 0.019 15.5 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI34438.1 - 0.00019 20.8 0.1 0.93 8.8 0.1 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KPI34438.1 - 0.00021 20.6 0.1 0.029 13.6 0.0 2.9 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 KPI34438.1 - 0.0023 17.2 1.0 0.11 11.8 0.0 2.6 1 1 2 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KPI34438.1 - 0.0024 18.3 0.0 0.17 12.4 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KPI34438.1 - 0.011 14.8 0.1 0.068 12.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KPI34438.1 - 0.015 15.4 0.1 0.45 10.6 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KPI34438.1 - 0.026 13.6 0.1 1.4 7.9 0.1 2.8 2 1 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KPI34438.1 - 0.049 13.0 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KPI34439.1 - 1.5e-07 30.7 0.5 2.3e-07 30.1 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PEP_mutase PF13714.6 KPI34440.1 - 2.3e-47 161.5 0.1 2.8e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KPI34440.1 - 3.9e-18 65.3 0.1 5e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family CAMSAP_CC1 PF17095.5 KPI34442.1 - 0.00016 21.4 0.1 0.0003 20.6 0.1 1.4 1 0 0 1 1 1 1 Spectrin-binding region of Ca2+-Calmodulin CCDC154 PF15450.6 KPI34442.1 - 0.00048 18.8 4.3 0.0006 18.5 4.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 DIRP PF06584.13 KPI34442.1 - 0.014 15.6 1.5 0.033 14.4 0.2 2.0 1 1 0 2 2 2 0 DIRP DUF4407 PF14362.6 KPI34442.1 - 0.025 13.9 6.2 0.027 13.8 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_G_2 PF16999.5 KPI34442.1 - 0.028 14.8 13.1 0.055 13.9 13.0 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF948 PF06103.11 KPI34442.1 - 0.032 14.5 0.5 4.4 7.6 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KPI34442.1 - 0.29 11.1 5.0 0.55 10.3 0.9 2.4 2 1 1 3 3 3 0 Laminin Domain II YtxH PF12732.7 KPI34442.1 - 0.99 10.0 4.8 25 5.5 4.8 2.3 1 1 0 1 1 1 0 YtxH-like protein GrpE PF01025.19 KPI34442.1 - 2.7 7.6 9.6 10 5.7 9.6 1.8 1 1 0 1 1 1 0 GrpE DUF883 PF05957.13 KPI34442.1 - 5.7 7.6 11.9 6.6 7.4 1.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 KPI34442.1 - 9.6 6.5 11.0 33 4.8 11.0 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Aconitase PF00330.20 KPI34444.1 - 5.8e-68 230.0 0.7 5.5e-46 157.5 0.1 2.3 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPI34444.1 - 2.4e-13 50.6 0.0 4.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.18 KPI34445.1 - 8.9e-11 41.3 0.7 1.1e-09 37.7 0.1 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Peptidase_M20 PF01546.28 KPI34446.1 - 1.4e-23 83.7 0.0 1.7e-19 70.4 0.0 2.6 3 0 0 3 3 3 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI34446.1 - 9.6e-06 25.5 0.4 3.1e-05 23.8 0.4 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 KPI34446.1 - 0.00027 21.7 0.4 0.47 11.4 0.2 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI34446.1 - 0.00033 20.9 0.1 0.095 13.0 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 KPI34446.1 - 0.0068 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PQQ_2 PF13360.6 KPI34446.1 - 0.022 14.3 0.0 0.17 11.4 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KPI34446.1 - 0.071 13.6 1.2 11 6.6 0.5 3.4 2 0 0 2 2 2 0 PQQ-like domain DEAD PF00270.29 KPI34447.1 - 1.7e-42 145.1 0.0 6.8e-42 143.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI34447.1 - 2.1e-24 86.0 0.0 4.3e-23 81.8 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI34447.1 - 1.1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HAD_2 PF13419.6 KPI34448.1 - 4.6e-06 26.8 0.0 7.6e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI34448.1 - 0.047 14.0 0.0 0.074 13.3 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NFACT-C PF11923.8 KPI34449.1 - 2.4e-33 114.2 0.1 2.4e-33 114.2 0.1 4.4 5 0 0 5 5 5 1 NFACT protein C-terminal domain FbpA PF05833.11 KPI34449.1 - 5.8e-30 104.4 13.2 6.7e-24 84.5 0.0 2.8 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KPI34449.1 - 1.6e-24 86.6 0.0 6.6e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain adh_short PF00106.25 KPI34450.1 - 2.9e-27 95.4 0.0 6.8e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34450.1 - 2e-19 70.1 0.0 4.5e-19 68.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34450.1 - 0.019 14.9 0.3 0.019 14.9 0.3 2.7 3 1 0 3 3 3 0 KR domain Eno-Rase_NADH_b PF12242.8 KPI34450.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn-ribbon_8 PF09723.10 KPI34450.1 - 0.2 11.8 0.8 0.42 10.8 0.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain EBP PF05241.12 KPI34452.1 - 1.2e-53 181.2 9.5 1.6e-53 180.8 9.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein PTR2 PF00854.21 KPI34454.1 - 8.9e-92 307.9 6.4 1.6e-91 307.1 6.4 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KPI34454.1 - 8.8e-06 24.9 21.7 1.5e-05 24.1 19.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KPI34454.1 - 4.9 7.5 4.7 28 5.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Acetyltransf_10 PF13673.7 KPI34456.1 - 4.5e-11 42.8 0.0 7.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI34456.1 - 1e-10 41.9 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI34456.1 - 1.5e-09 38.1 0.1 3.3e-09 37.0 0.1 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KPI34456.1 - 0.0075 16.3 0.1 0.043 13.9 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI34456.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KPI34456.1 - 0.19 11.7 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase ABC_tran PF00005.27 KPI34457.1 - 3.8e-44 150.5 0.0 9e-23 81.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPI34457.1 - 1.6e-30 106.7 38.3 4.6e-24 85.5 14.2 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KPI34457.1 - 2.9e-13 49.8 0.3 0.00015 21.3 0.3 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPI34457.1 - 1.4e-08 34.9 3.3 0.013 15.3 0.1 4.2 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPI34457.1 - 4.1e-06 26.4 1.3 0.0049 16.6 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPI34457.1 - 7.3e-06 26.3 0.9 0.017 15.4 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPI34457.1 - 3.7e-05 24.2 0.0 0.19 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPI34457.1 - 5.5e-05 23.1 0.2 0.42 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KPI34457.1 - 8.2e-05 22.8 0.3 0.019 15.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KPI34457.1 - 0.00013 21.4 0.1 0.11 11.8 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_7 PF12775.7 KPI34457.1 - 0.00018 21.1 0.1 0.027 14.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KPI34457.1 - 0.00034 21.0 0.0 0.4 11.1 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KPI34457.1 - 0.00052 19.8 0.1 1 9.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KPI34457.1 - 0.0006 19.8 0.1 2.4 8.1 0.0 3.2 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KPI34457.1 - 0.0034 16.5 0.0 0.24 10.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KPI34457.1 - 0.004 17.2 0.2 4.9 7.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 KPI34457.1 - 0.0057 15.6 0.3 0.36 9.7 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.26 KPI34457.1 - 0.01 15.6 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain cobW PF02492.19 KPI34457.1 - 0.012 15.2 0.3 0.1 12.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KPI34457.1 - 0.014 15.3 0.4 0.91 9.4 0.0 2.8 3 0 0 3 3 2 0 NACHT domain DUF87 PF01935.17 KPI34457.1 - 0.014 15.5 1.7 4.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KPI34457.1 - 0.026 15.1 1.9 0.26 11.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPI34457.1 - 0.027 13.7 0.5 0.61 9.2 0.3 2.7 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KPI34457.1 - 0.04 13.1 0.1 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KPI34457.1 - 0.041 13.2 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 KPI34457.1 - 0.05 13.3 0.1 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KPI34457.1 - 0.055 13.8 0.1 6.3 7.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI34457.1 - 0.072 12.8 0.1 9.1 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI34457.1 - 0.079 13.5 0.0 7.2 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KPI34457.1 - 0.082 12.4 0.2 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.15 KPI34457.1 - 0.091 12.7 1.2 14 5.6 0.0 3.2 3 0 0 3 3 3 0 NTPase TsaE PF02367.17 KPI34457.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KPI34457.1 - 0.12 12.8 0.3 23 5.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.17 KPI34457.1 - 0.12 12.1 0.3 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KPI34457.1 - 0.14 12.2 0.7 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 KPI34457.1 - 0.16 11.5 0.3 2 7.9 0.0 2.6 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain Motile_Sperm PF00635.26 KPI34458.1 - 2.3e-11 43.5 0.0 3.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PRKG1_interact PF15898.5 KPI34458.1 - 0.036 15.0 3.9 0.94 10.4 0.3 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mito_carr PF00153.27 KPI34460.1 - 5.4e-52 173.7 1.2 6.3e-20 70.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI34460.1 - 0.15 11.2 0.2 1 8.4 0.0 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease FAD_binding_2 PF00890.24 KPI34461.1 - 6.1e-44 150.7 0.4 7.2e-43 147.2 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI34461.1 - 3.2e-10 40.1 2.2 1.6e-09 37.8 0.0 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPI34461.1 - 5.5e-07 29.3 0.1 4.1e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI34461.1 - 0.00017 21.7 0.1 0.00055 20.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI34461.1 - 0.00019 20.7 0.6 0.00035 19.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KPI34461.1 - 0.00024 19.9 0.0 0.0021 16.8 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPI34461.1 - 0.00032 20.0 0.0 0.0034 16.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KPI34461.1 - 0.00045 19.7 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI34461.1 - 0.0005 19.2 0.0 0.00076 18.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KPI34461.1 - 0.01 15.0 2.1 0.037 13.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KPI34461.1 - 0.051 14.1 0.0 24 5.6 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApoO PF09769.9 KPI34463.1 - 5.9e-39 133.0 0.1 2.9e-38 130.8 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O VHS PF00790.19 KPI34464.1 - 3.2e-18 65.9 0.0 6.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KPI34464.1 - 7e-06 26.3 0.6 6.7e-05 23.1 0.1 2.8 2 0 0 2 2 2 1 GAT domain ENTH PF01417.20 KPI34464.1 - 0.00077 19.5 0.0 0.0099 15.9 0.0 2.5 2 1 1 3 3 3 1 ENTH domain ArfGap PF01412.18 KPI34465.1 - 3.5e-41 140.0 1.0 4.9e-41 139.5 1.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NicO PF03824.16 KPI34466.1 - 1.5e-53 182.0 18.7 6.7e-53 179.9 7.5 2.6 3 0 0 3 3 3 2 High-affinity nickel-transport protein HemY_N PF07219.13 KPI34466.1 - 6.9 6.9 11.1 17 5.7 1.7 4.2 4 0 0 4 4 4 0 HemY protein N-terminus GFA PF04828.14 KPI34467.1 - 2.9e-22 78.8 0.0 4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PSDC PF12588.8 KPI34468.1 - 4.4e-56 188.8 0.0 7.4e-56 188.0 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KPI34468.1 - 4.9e-39 134.0 0.0 6.8e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KPI34468.1 - 0.0017 18.1 0.4 0.23 11.3 0.2 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 KPI34468.1 - 0.13 12.0 0.2 0.32 10.8 0.2 1.6 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RIO1 PF01163.22 KPI34469.1 - 1.8e-67 226.6 0.6 1.8e-67 226.6 0.6 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KPI34469.1 - 0.067 13.1 0.2 2.5 7.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KPI34469.1 - 0.14 11.5 1.7 4.5 6.6 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pneumo_att_G PF05539.11 KPI34469.1 - 0.4 10.2 8.2 0.59 9.7 8.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Aldolase_II PF00596.21 KPI34470.1 - 1.8e-30 106.3 0.1 3e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Tht1 PF04163.12 KPI34471.1 - 0.0067 15.2 1.1 0.032 13.0 0.2 2.0 2 0 0 2 2 2 1 Tht1-like nuclear fusion protein Sulf_transp PF04143.14 KPI34471.1 - 0.0085 15.7 0.3 0.014 15.0 0.3 1.2 1 0 0 1 1 1 1 Sulphur transport SMC_N PF02463.19 KPI34472.1 - 1.5e-49 168.4 43.9 1e-48 165.7 43.9 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPI34472.1 - 3.4e-29 101.5 0.1 5.6e-28 97.6 0.0 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KPI34472.1 - 8.9e-17 61.8 4.6 4.1e-09 36.7 0.2 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPI34472.1 - 6.8e-13 49.6 26.2 6.8e-13 49.6 26.2 7.3 2 2 3 6 6 6 1 AAA domain AAA_15 PF13175.6 KPI34472.1 - 8.9e-12 45.4 76.3 2.9e-09 37.1 32.7 4.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KPI34472.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain YlbE PF14003.6 KPI34472.1 - 0.68 10.4 4.0 1.2 9.6 0.1 3.7 4 0 0 4 4 4 0 YlbE-like protein Dfp1_Him1_M PF08630.10 KPI34473.1 - 1.2e-33 116.1 0.3 6.2e-33 113.7 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KPI34473.1 - 4.9e-22 77.8 0.2 8.2e-22 77.1 0.2 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KPI34473.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain MTS PF05175.14 KPI34474.1 - 0.00029 20.4 0.0 0.00096 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NTP_transferase PF00483.23 KPI34475.1 - 7.9e-30 104.2 0.0 9.9e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KPI34475.1 - 1.9e-08 33.7 7.3 7.2e-06 25.5 0.1 3.4 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KPI34475.1 - 2e-05 25.0 0.0 3.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KPI34475.1 - 0.04 12.9 0.1 4.7 6.0 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 KPI34475.1 - 0.046 13.5 0.5 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.26 KPI34475.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Abhydrolase_1 PF00561.20 KPI34476.1 - 2.1e-21 76.7 0.1 8.9e-20 71.4 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI34476.1 - 4.4e-14 52.4 0.0 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Pkinase PF00069.25 KPI34477.1 - 1.8e-12 47.2 0.0 1.7e-09 37.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI34477.1 - 1.1e-05 24.9 0.1 0.048 12.9 0.0 3.3 2 2 0 2 2 2 2 Protein tyrosine kinase APG17 PF04108.12 KPI34478.1 - 1.3e-106 357.1 6.8 1.5e-106 356.9 6.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Pex19 PF04614.12 KPI34478.1 - 0.013 15.2 1.3 0.023 14.5 0.6 1.8 2 0 0 2 2 2 0 Pex19 protein family Glutaredoxin2_C PF04399.13 KPI34478.1 - 0.033 14.0 1.2 0.1 12.5 0.1 2.3 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain ApoLp-III PF07464.11 KPI34478.1 - 0.064 13.3 8.0 0.52 10.4 0.7 3.3 3 2 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Med9 PF07544.13 KPI34478.1 - 0.077 13.1 4.2 0.8 9.8 0.9 3.8 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Allexi_40kDa PF05549.11 KPI34478.1 - 0.093 12.2 6.1 0.69 9.4 0.2 3.0 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF1664 PF07889.12 KPI34478.1 - 0.1 12.7 10.7 1.2 9.2 0.2 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) GIT1_C PF12205.8 KPI34478.1 - 0.13 12.4 0.6 0.37 10.9 0.1 2.0 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term NPV_P10 PF05531.12 KPI34478.1 - 0.24 11.9 5.7 3.9 8.0 0.9 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KPI34478.1 - 0.28 11.5 7.6 5.7 7.3 1.4 4.6 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Tektin PF03148.14 KPI34478.1 - 0.37 9.5 10.5 1.5 7.5 0.4 3.0 3 0 0 3 3 3 0 Tektin family XhlA PF10779.9 KPI34478.1 - 0.54 10.5 4.4 5 7.4 1.9 3.1 2 0 0 2 2 2 0 Haemolysin XhlA GAT PF03127.14 KPI34478.1 - 0.75 10.1 4.9 30 5.0 0.6 3.6 3 0 0 3 3 3 0 GAT domain GCIP PF13324.6 KPI34478.1 - 1.3 8.6 7.4 5.3 6.6 3.3 2.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Prominin PF05478.11 KPI34478.1 - 2.2 6.2 3.8 11 3.8 0.2 2.5 3 0 0 3 3 3 0 Prominin PTRF_SDPR PF15237.6 KPI34478.1 - 2.9 7.4 6.2 7.5 6.1 0.1 2.6 3 0 0 3 3 3 0 PTRF/SDPR family Fib_alpha PF08702.10 KPI34478.1 - 3.2 8.0 4.7 4.1 7.6 0.4 3.0 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 KPI34478.1 - 6.7 7.2 9.9 49 4.4 0.4 4.1 4 1 1 5 5 5 0 Snapin/Pallidin Cep57_MT_bd PF06657.13 KPI34478.1 - 6.8 7.2 8.0 4.3 7.9 0.4 3.9 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DLP_helical PF18709.1 KPI34478.1 - 8 5.6 6.9 1.8 7.7 0.5 2.5 2 0 0 2 2 2 0 Dynamin-like helical domain WD40 PF00400.32 KPI34479.1 - 4.5e-42 141.2 28.0 5.1e-06 27.1 0.3 8.5 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KPI34479.1 - 4.2e-12 45.8 0.2 8.8e-12 44.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI34479.1 - 1e-09 38.0 0.1 2.3e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KPI34479.1 - 6.4e-09 35.0 9.6 0.045 12.4 0.1 5.5 4 1 2 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KPI34479.1 - 1.3e-05 25.4 0.8 0.24 11.7 0.0 4.7 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KPI34479.1 - 2.1e-05 24.3 1.3 6.6e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 F-box MFS_1 PF07690.16 KPI34480.1 - 5.2e-25 88.1 30.0 5.2e-25 88.1 30.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Inositol_P PF00459.25 KPI34481.1 - 4.2e-52 177.3 2.4 1.7e-51 175.4 2.4 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 KPI34482.1 - 5.1e-59 199.8 0.0 6.5e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI34482.1 - 3.4e-34 118.3 0.0 4.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPI34482.1 - 0.00023 20.6 0.3 0.00052 19.4 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI34482.1 - 0.001 19.1 1.0 0.0022 17.9 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI34482.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPI34482.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KPI34482.1 - 0.039 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Endonuc_Holl PF10107.9 KPI34482.1 - 0.043 13.7 0.1 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Zds_C PF08632.10 KPI34483.1 - 1.5e-28 98.2 1.5 3.2e-28 97.2 1.5 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CsbD PF05532.12 KPI34484.1 - 0.097 12.6 4.5 0.27 11.2 4.5 1.7 1 0 0 1 1 1 0 CsbD-like F-box-like PF12937.7 KPI34485.1 - 0.00052 19.8 0.2 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 KPI34485.1 - 0.018 15.1 0.2 0.23 11.7 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI34485.1 - 0.11 12.4 0.1 15 5.6 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 KPI34486.1 - 6.2e-62 209.8 0.0 8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KPI34487.1 - 0.0084 16.0 0.8 0.071 13.0 0.8 2.2 1 1 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KPI34487.1 - 0.043 13.7 0.0 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 F-box Podoplanin PF05808.11 KPI34488.1 - 0.0087 16.2 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Podoplanin DASH_Duo1 PF08651.10 KPI34488.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.7 1 1 1 2 2 2 0 DASH complex subunit Duo1 CTP_synth_N PF06418.14 KPI34489.1 - 6.7e-123 409.2 0.1 8.7e-123 408.8 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KPI34489.1 - 9.4e-57 191.9 0.0 1.5e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KPI34489.1 - 7.3e-06 25.9 0.2 7.1e-05 22.7 0.3 2.4 2 1 0 2 2 2 1 Peptidase C26 Ribosomal_L6 PF00347.23 KPI34490.1 - 2e-21 76.4 0.0 7.2e-12 45.8 0.0 2.7 2 1 0 2 2 2 2 Ribosomal protein L6 Sugar_tr PF00083.24 KPI34492.1 - 6.7e-101 338.4 19.9 7.5e-101 338.2 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34492.1 - 1.7e-16 60.1 15.5 1.7e-16 60.1 15.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KPI34493.1 - 2.6e-36 125.3 42.1 7.3e-34 117.2 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI34493.1 - 1.6e-09 37.2 1.1 1.6e-09 37.2 1.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI34493.1 - 0.014 13.9 0.2 0.014 13.9 0.2 2.4 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) DUF3806 PF12713.7 KPI34493.1 - 0.048 13.4 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) MFS_2 PF13347.6 KPI34493.1 - 0.083 11.4 15.7 0.67 8.4 0.5 2.4 2 0 0 2 2 2 0 MFS/sugar transport protein MFS_1_like PF12832.7 KPI34493.1 - 1.1 8.0 13.3 0.12 11.2 1.4 2.8 2 1 1 3 3 3 0 MFS_1 like family RTA1 PF04479.13 KPI34494.1 - 4e-69 232.4 5.9 5.2e-69 232.0 5.9 1.1 1 0 0 1 1 1 1 RTA1 like protein UPF0220 PF05255.11 KPI34494.1 - 0.037 13.6 0.4 0.11 12.1 0.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) Peptidase_U4 PF03419.13 KPI34494.1 - 1.1 8.5 7.9 14 4.9 7.6 2.2 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Bac_luciferase PF00296.20 KPI34495.1 - 5.3e-33 114.8 0.2 6.3e-33 114.5 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase FAD_binding_3 PF01494.19 KPI34497.1 - 1.1e-26 93.9 0.0 7.1e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI34497.1 - 0.00015 21.9 2.6 0.0025 18.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34497.1 - 0.00058 19.2 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI34497.1 - 0.003 17.2 1.6 0.013 15.1 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KPI34497.1 - 0.0049 16.4 0.1 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus SE PF08491.10 KPI34497.1 - 0.01 14.9 0.0 0.033 13.2 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 KPI34497.1 - 0.033 12.9 0.0 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KPI34497.1 - 0.06 12.2 0.1 0.97 8.2 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KPI34497.1 - 0.076 12.1 0.4 0.15 11.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPI34497.1 - 0.087 12.0 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KPI34497.1 - 0.1 11.8 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI34497.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAA_hydrolase PF01557.18 KPI34498.1 - 3.5e-54 183.7 0.0 4.9e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.8 KPI34498.1 - 0.14 12.8 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 87kDa Transposase Transp_cyt_pur PF02133.15 KPI34499.1 - 7.8e-67 226.0 40.4 8.9e-67 225.8 40.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 KPI34500.1 - 5.1e-30 104.6 22.6 8e-30 103.9 22.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI34500.1 - 3.4e-07 29.9 2.5 3.4e-07 29.9 2.5 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LicD PF04991.13 KPI34501.1 - 6.5e-20 72.2 5.3 2.7e-13 50.6 1.5 2.3 1 1 1 2 2 2 2 LicD family NMO PF03060.15 KPI34502.1 - 7.6e-28 97.9 9.4 1.8e-26 93.3 9.4 2.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI34502.1 - 0.00064 18.8 0.3 1.2 8.0 0.0 2.3 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KPI34502.1 - 0.0098 15.1 0.5 0.014 14.5 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NAD_binding_10 PF13460.6 KPI34503.1 - 0.057 13.3 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding ADH_zinc_N PF00107.26 KPI34504.1 - 5.5e-09 36.1 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI34504.1 - 1.4e-08 34.6 0.0 1.6e-07 31.2 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MSP1b PF03429.13 KPI34504.1 - 0.023 12.8 0.4 0.034 12.3 0.4 1.2 1 0 0 1 1 1 0 Major surface protein 1B CFEM PF05730.11 KPI34505.1 - 1.1e-11 44.6 8.1 2.2e-11 43.7 8.1 1.5 1 0 0 1 1 1 1 CFEM domain IDO PF01231.18 KPI34506.1 - 1.8e-35 122.6 0.0 2.6e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Sugar_tr PF00083.24 KPI34507.1 - 1e-40 140.0 21.5 3.5e-40 138.2 21.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34507.1 - 1.4e-28 99.8 26.9 1.4e-28 99.8 26.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PrpF PF04303.13 KPI34508.1 - 2.1e-35 122.4 1.7 2.3e-35 122.3 1.7 1.0 1 0 0 1 1 1 1 PrpF protein Pro_racemase PF05544.11 KPI34508.1 - 0.018 14.1 0.3 0.02 13.9 0.3 1.0 1 0 0 1 1 1 0 Proline racemase Mito_carr PF00153.27 KPI34509.1 - 2.1e-48 162.2 5.9 1.1e-16 60.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.6 KPI34509.1 - 0.024 14.9 1.2 0.043 14.1 0.1 2.0 2 1 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation DUF4148 PF13663.6 KPI34509.1 - 2 8.7 6.8 4.1 7.7 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4148) Fungal_trans PF04082.18 KPI34510.1 - 2.3e-05 23.6 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VacA PF02691.15 KPI34510.1 - 0.031 12.1 0.4 0.044 11.7 0.4 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin P5CR_dimer PF14748.6 KPI34511.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF4286 PF14114.6 KPI34512.1 - 0.07 13.6 0.1 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Fungal_trans PF04082.18 KPI34513.1 - 1e-21 77.2 0.0 1.4e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_luciferase PF00296.20 KPI34514.1 - 7.2e-53 180.0 0.0 9.5e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2673 PF10880.8 KPI34515.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Oxidored_FMN PF00724.20 KPI34516.1 - 9e-68 229.0 0.0 1.1e-66 225.5 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_7 PF03441.14 KPI34517.1 - 2.7e-81 271.9 0.5 5.1e-81 271.0 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPI34517.1 - 6.5e-36 123.8 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Isochorismatase PF00857.20 KPI34518.1 - 2.1e-22 80.1 0.0 2.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DDE_Tnp_1_7 PF13843.6 KPI34518.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 MFS_1 PF07690.16 KPI34519.1 - 7e-40 137.0 26.0 7e-40 137.0 26.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI34519.1 - 8.7e-16 57.8 6.7 8.7e-16 57.8 6.7 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPI34519.1 - 3.3e-06 25.8 0.2 3.3e-06 25.8 0.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KPI34519.1 - 0.0011 17.3 4.7 0.011 14.1 4.7 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4179 PF13786.6 KPI34519.1 - 0.19 12.3 0.6 6.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF3040 PF11239.8 KPI34519.1 - 6.7 7.1 10.2 2.7 8.3 0.2 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) Fungal_trans PF04082.18 KPI34520.1 - 1.2e-23 83.6 0.1 1.6e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PrpF PF04303.13 KPI34520.1 - 1.2e-15 57.3 0.3 2e-15 56.6 0.3 1.3 1 0 0 1 1 1 1 PrpF protein EHN PF06441.12 KPI34521.1 - 1.1e-36 125.5 0.9 2.4e-36 124.4 0.9 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI34521.1 - 4e-06 26.7 0.0 7.3e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mrr_cat PF04471.12 KPI34521.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease PI31_Prot_N PF11566.8 KPI34521.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal DUF4841 PF16129.5 KPI34522.1 - 0.02 15.1 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) zf-C2H2 PF00096.26 KPI34523.1 - 2.3e-05 24.6 12.0 0.034 14.6 4.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI34523.1 - 0.0002 21.9 11.0 0.014 16.2 3.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPI34523.1 - 0.00055 20.2 11.6 0.011 16.1 2.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 KPI34523.1 - 3.3 7.6 4.9 1.2 9.0 0.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type GMC_oxred_N PF00732.19 KPI34524.1 - 5.7e-46 157.2 0.0 2.2e-43 148.7 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI34524.1 - 5.3e-32 111.3 0.0 1e-31 110.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI34524.1 - 1.4e-06 27.6 0.2 2.3e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI34524.1 - 0.0013 17.9 0.2 0.031 13.4 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI34524.1 - 0.0017 18.5 0.1 0.0056 16.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI34524.1 - 0.0017 18.0 3.1 0.026 14.1 3.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI34524.1 - 0.01 15.1 0.1 0.037 13.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KPI34524.1 - 0.022 14.0 0.0 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI34524.1 - 0.096 11.9 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI34524.1 - 0.26 9.9 0.0 0.51 9.0 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.22 KPI34525.1 - 2.6e-131 438.4 0.7 3e-131 438.1 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI34525.1 - 0.00025 20.6 0.0 0.0033 16.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) NAD_binding_3 PF03447.16 KPI34525.1 - 0.089 13.5 0.0 0.33 11.6 0.0 1.9 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ank_2 PF12796.7 KPI34526.1 - 3.8e-54 181.2 0.5 4.6e-11 43.2 0.2 6.3 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI34526.1 - 1.8e-41 139.7 0.8 2.8e-06 27.5 0.0 8.5 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPI34526.1 - 6.5e-39 131.8 2.8 1.1e-06 29.0 0.0 10.3 5 4 8 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI34526.1 - 9.3e-35 114.7 6.5 0.0016 18.7 0.0 13.9 14 0 0 14 14 14 9 Ankyrin repeat Ank PF00023.30 KPI34526.1 - 2.8e-27 93.9 9.5 0.0073 16.7 0.2 13.0 12 2 2 14 14 14 7 Ankyrin repeat adh_short PF00106.25 KPI34527.1 - 2e-25 89.4 1.0 1.8e-24 86.3 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34527.1 - 4.1e-19 69.1 0.4 3e-18 66.3 0.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34527.1 - 8e-05 22.6 0.1 0.00018 21.4 0.1 1.5 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 KPI34527.1 - 0.041 13.5 0.3 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPI34527.1 - 0.08 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KPI34529.1 - 1.4e-22 80.2 0.0 1.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34529.1 - 2e-09 37.4 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPI34529.1 - 0.0015 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI34529.1 - 0.0035 16.8 0.0 0.9 8.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI34529.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KPI34529.1 - 0.034 13.7 0.1 0.069 12.7 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family S_100 PF01023.19 KPI34529.1 - 0.053 13.2 0.2 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain TrkA_N PF02254.18 KPI34529.1 - 0.059 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain SnoaL PF07366.12 KPI34530.1 - 8.3e-05 22.4 0.0 0.0005 19.9 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPI34530.1 - 0.0045 17.6 0.0 0.0068 17.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Duffy_binding PF05424.11 KPI34531.1 - 0.071 13.2 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Duffy binding domain UDPGT PF00201.18 KPI34533.1 - 6.3e-14 51.7 0.0 9.1e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase COX15-CtaA PF02628.15 KPI34533.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Peptidase_M13_N PF05649.13 KPI34534.1 - 1.4e-73 248.8 0.0 2.1e-37 129.7 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 KPI34534.1 - 1.2e-63 214.4 0.5 1.9e-63 213.8 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M13 CamS PF07537.11 KPI34534.1 - 0.03 13.5 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor TRI12 PF06609.13 KPI34535.1 - 1.4e-23 83.2 27.6 1.8e-23 82.8 27.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI34535.1 - 7.8e-16 57.9 55.1 7.8e-16 57.9 55.1 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily IL2 PF00715.17 KPI34536.1 - 0.047 13.6 0.7 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Interleukin 2 DUF417 PF04224.12 KPI34536.1 - 0.1 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF417 ABC2_membrane PF01061.24 KPI34536.1 - 0.16 11.3 7.8 0.26 10.7 7.8 1.2 1 0 0 1 1 1 0 ABC-2 type transporter DUF2070 PF09843.9 KPI34536.1 - 3.3 5.9 8.5 4.8 5.3 8.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Putative_PNPOx PF01243.20 KPI34537.1 - 0.0005 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TFR_dimer PF04253.15 KPI34538.1 - 3.8e-24 85.1 0.0 7.1e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KPI34538.1 - 6e-20 71.8 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPI34538.1 - 9.3e-09 35.2 2.6 9.8e-09 35.1 0.1 2.5 2 1 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KPI34538.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Aldedh PF00171.22 KPI34539.1 - 2.3e-181 603.4 0.6 2.5e-181 603.2 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amidohydro_2 PF04909.14 KPI34540.1 - 8.4e-24 84.8 0.0 1.4e-23 84.1 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase BRCA-2_OB3 PF09104.10 KPI34540.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 adh_short PF00106.25 KPI34541.1 - 6.2e-43 146.5 0.0 7.5e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34541.1 - 6.8e-32 110.9 0.0 8.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34541.1 - 3.7e-06 27.0 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI34541.1 - 4.8e-05 23.0 0.1 0.00019 21.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI34541.1 - 0.0026 17.2 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KPI34541.1 - 0.0041 17.1 0.3 0.025 14.6 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KPI34541.1 - 0.015 15.2 0.1 0.019 14.8 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI34541.1 - 0.079 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SIS PF01380.22 KPI34541.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 SIS domain gag-asp_proteas PF13975.6 KPI34542.1 - 2.9e-09 37.4 0.0 0.0039 17.7 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KPI34542.1 - 1.9e-06 27.7 0.0 0.001 18.9 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease Asp_protease_2 PF13650.6 KPI34542.1 - 1.6e-05 25.4 0.0 0.018 15.7 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease DUF1221 PF06760.11 KPI34542.1 - 0.02 14.4 0.3 0.038 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) REV1_C PF16727.5 KPI34542.1 - 0.061 13.7 0.1 7.7 7.0 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain SnoaL_4 PF13577.6 KPI34543.1 - 0.045 13.9 0.0 0.086 13.0 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain NUC153 PF08159.12 KPI34544.1 - 1.2e-11 44.2 0.8 2.4e-10 40.0 0.0 2.7 2 0 0 2 2 2 1 NUC153 domain Fungal_trans PF04082.18 KPI34545.1 - 9.9e-16 57.6 0.2 4.5e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Slx4 PF09494.10 KPI34545.1 - 0.14 12.1 0.2 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Slx4 endonuclease FAD_binding_3 PF01494.19 KPI34546.1 - 6.1e-22 78.3 0.0 9.5e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI34546.1 - 2.5e-05 24.0 8.6 0.028 14.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI34546.1 - 4.5e-05 23.6 2.4 4.9e-05 23.5 0.9 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI34546.1 - 7e-05 22.3 0.7 0.12 11.7 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KPI34546.1 - 8.5e-05 21.6 0.0 8.5e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KPI34546.1 - 0.00046 19.5 8.0 0.014 14.7 3.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI34546.1 - 0.00057 19.1 4.2 0.00057 19.1 4.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KPI34546.1 - 0.0084 16.7 1.7 0.046 14.3 1.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI34546.1 - 0.021 14.2 0.5 0.038 13.3 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI34546.1 - 0.036 13.3 2.2 0.066 12.5 2.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI34546.1 - 0.043 12.5 3.2 0.72 8.5 2.5 2.1 2 0 0 2 2 2 0 HI0933-like protein Lebercilin PF15619.6 KPI34547.1 - 0.012 15.3 1.4 0.012 15.3 1.4 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 KPI34547.1 - 2.3 8.4 13.2 0.35 11.1 8.3 2.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Aldo_ket_red PF00248.21 KPI34548.1 - 4.8e-38 131.0 0.0 9.5e-28 97.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family ADH_N PF08240.12 KPI34549.1 - 2.6e-23 82.0 0.8 6.5e-23 80.7 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI34549.1 - 7e-23 81.0 0.1 1.2e-22 80.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI34549.1 - 1.6e-08 35.7 0.0 3.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI34549.1 - 1.2e-07 31.4 0.1 1.8e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPI34549.1 - 0.011 15.1 0.9 0.02 14.2 0.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain WH1 PF00568.23 KPI34549.1 - 0.18 11.7 0.0 0.76 9.7 0.0 1.9 2 0 0 2 2 2 0 WH1 domain Fungal_trans_2 PF11951.8 KPI34551.1 - 2e-06 26.9 0.4 0.00026 19.9 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain FMO-like PF00743.19 KPI34552.1 - 1.6e-09 36.8 0.0 4.8e-08 31.9 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI34552.1 - 3e-05 23.3 0.0 0.00041 19.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI34552.1 - 5.3e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34552.1 - 0.00012 21.4 0.0 0.0025 17.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KPI34552.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cupin_2 PF07883.11 KPI34553.1 - 1.1e-18 66.6 0.3 4.4e-18 64.8 0.2 2.0 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KPI34553.1 - 0.00038 20.4 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 KPI34553.1 - 0.0027 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_3 PF05899.12 KPI34553.1 - 0.022 14.4 0.2 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Auxin_BP PF02041.16 KPI34553.1 - 0.037 13.7 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Auxin binding protein FAA_hydrolase PF01557.18 KPI34554.1 - 2.1e-59 200.8 0.0 2.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family adh_short_C2 PF13561.6 KPI34555.1 - 7.2e-54 182.8 2.6 8.3e-54 182.6 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI34555.1 - 2.1e-49 167.7 2.2 2.7e-49 167.3 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI34555.1 - 1.1e-13 51.4 0.8 1.5e-13 51.0 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI34555.1 - 8e-08 32.0 0.3 1.2e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI34555.1 - 3.1e-05 23.6 1.4 5.6e-05 22.7 1.4 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPI34555.1 - 0.00088 18.5 0.4 0.0011 18.2 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 KPI34555.1 - 0.0017 17.9 0.2 0.0031 17.1 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.19 KPI34555.1 - 0.005 16.2 0.2 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KPI34555.1 - 0.0075 16.2 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KPI34555.1 - 0.14 12.9 0.1 0.25 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain PAN_1 PF00024.26 KPI34556.1 - 2.3e-12 46.7 9.2 2.1e-05 24.4 0.4 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 KPI34556.1 - 0.0046 16.8 21.9 0.13 12.2 2.2 4.1 3 2 0 3 3 3 3 PAN domain Phage_holin_2_4 PF16082.5 KPI34556.1 - 0.027 14.2 0.5 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF3042 PF11240.8 KPI34556.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) AtuA PF07287.11 KPI34557.1 - 3.6e-73 246.3 0.2 1.1e-38 132.9 0.4 3.1 1 1 2 3 3 3 3 Acyclic terpene utilisation family protein AtuA Auxin_BP PF02041.16 KPI34558.1 - 0.057 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein DLH PF01738.18 KPI34559.1 - 1.5e-08 34.5 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family AA_permease_2 PF13520.6 KPI34560.1 - 1.7e-43 149.0 46.0 2.1e-43 148.7 46.0 1.1 1 0 0 1 1 1 1 Amino acid permease MIP PF00230.20 KPI34561.1 - 1.7e-47 162.1 17.7 2.1e-47 161.7 17.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cornifin PF02389.15 KPI34562.1 - 3.3e-05 24.1 0.7 4.1e-05 23.8 0.7 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family Mac PF12464.8 KPI34563.1 - 1.2e-14 54.3 0.0 2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KPI34563.1 - 3.5e-13 48.7 7.6 4.7e-11 42.0 3.1 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPI34563.1 - 7.7e-12 44.8 7.6 4.3e-09 36.0 2.2 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase rve_3 PF13683.6 KPI34563.1 - 0.043 13.6 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Integrase core domain TauD PF02668.16 KPI34564.1 - 6.9e-41 140.8 0.6 1e-40 140.3 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KPI34565.1 - 4.1e-29 101.6 18.8 4.1e-29 101.6 18.8 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI34565.1 - 8.8e-12 44.6 4.7 8.8e-12 44.6 4.7 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TMEM187 PF15100.6 KPI34565.1 - 0.0042 16.7 0.4 0.0096 15.5 0.4 1.6 1 0 0 1 1 1 1 TMEM187 protein family Zip PF02535.22 KPI34566.1 - 0.0012 18.2 2.0 0.0013 18.0 2.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MmgE_PrpD PF03972.14 KPI34567.1 - 1.3e-126 422.7 0.3 3.4e-125 418.1 0.3 2.0 1 1 0 1 1 1 1 MmgE/PrpD family Zn_clus PF00172.18 KPI34568.1 - 1.9e-08 34.3 11.7 3e-08 33.7 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI34568.1 - 2.8e-08 33.0 0.0 4.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ApbA_C PF08546.11 KPI34569.1 - 2e-30 105.6 0.0 5.4e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPI34569.1 - 1.6e-27 96.0 0.0 2.5e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KPI34569.1 - 0.0026 18.2 0.0 0.0078 16.6 0.0 1.6 2 1 0 2 2 2 1 Putative NAD(P)-binding PRD PF00874.20 KPI34569.1 - 0.0098 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 PRD domain Toxin_23 PF08093.11 KPI34569.1 - 2.3 8.4 3.7 6.3 7.0 0.4 2.2 2 0 0 2 2 2 0 Magi 5 toxic peptide family AMP-binding PF00501.28 KPI34570.1 - 1.6e-74 251.0 0.0 2e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPI34570.1 - 1.4e-17 63.3 2.1 3.2e-17 62.2 2.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KPI34570.1 - 1.5e-05 25.8 0.0 4.5e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 KPI34571.1 - 2.8e-12 46.5 0.0 1.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI34571.1 - 3.7e-12 45.4 0.0 7.1e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI34571.1 - 2.1e-10 40.3 0.0 6.6e-09 35.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI34571.1 - 1.9e-09 37.6 0.0 5.1e-08 33.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34571.1 - 6.5e-07 28.9 0.0 2.1e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI34571.1 - 2.8e-05 23.9 0.7 0.057 13.0 0.1 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI34571.1 - 0.0045 16.1 0.0 0.0095 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KPI34571.1 - 0.0049 16.0 0.4 0.028 13.5 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pepsin-I3 PF06394.13 KPI34571.1 - 0.035 14.3 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain NAD_binding_9 PF13454.6 KPI34571.1 - 0.12 12.3 3.0 28 4.7 1.3 3.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 KPI34571.1 - 0.13 11.5 0.1 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Fungal_trans_2 PF11951.8 KPI34572.1 - 7.7e-05 21.7 0.3 0.00011 21.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 KPI34574.1 - 3.2e-52 178.0 0.2 4.1e-52 177.6 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mg_trans_NIPA PF05653.14 KPI34575.1 - 4.7e-91 305.0 28.2 6.6e-91 304.5 28.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KPI34575.1 - 7.3e-06 26.2 6.9 7.3e-06 26.2 6.9 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF805 PF05656.14 KPI34575.1 - 0.059 13.8 12.7 0.11 12.9 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) MFS_1 PF07690.16 KPI34576.1 - 1.2e-17 63.9 19.1 1.5e-17 63.5 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.24 KPI34577.1 - 2.5e-39 135.9 0.0 2.9e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI34577.1 - 4.9e-09 36.3 0.2 0.0014 18.6 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI34577.1 - 5e-09 36.3 0.0 1.6e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34577.1 - 5.4e-06 25.8 0.0 0.00011 21.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI34577.1 - 0.0084 14.9 0.0 0.023 13.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KPI34577.1 - 0.018 13.9 0.0 0.74 8.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KPI34577.1 - 0.018 14.1 0.0 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KPI34577.1 - 0.027 13.6 0.1 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 KPI34577.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KPI34577.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KPI34577.1 - 0.16 11.2 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI34577.1 - 0.17 11.0 0.0 6.7 5.8 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GSH-S_N PF02951.14 KPI34577.1 - 0.19 11.8 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Sugar_tr PF00083.24 KPI34578.1 - 9.9e-66 222.4 24.8 1.4e-63 215.3 17.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI34578.1 - 1.7e-18 66.7 29.2 1.7e-18 66.7 29.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OppC_N PF12911.7 KPI34578.1 - 0.12 12.4 5.7 3.5 7.7 0.4 3.3 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Phage_holin_2_4 PF16082.5 KPI34578.1 - 0.24 11.2 6.0 0.096 12.4 1.7 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ytp1 PF10355.9 KPI34579.1 - 8.8e-75 251.5 5.2 1.3e-74 250.9 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KPI34579.1 - 5.6e-23 80.7 0.3 5.6e-23 80.7 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF202 PF02656.15 KPI34579.1 - 0.44 11.0 0.1 0.44 11.0 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF202) DUF3237 PF11578.8 KPI34580.1 - 3.8e-40 137.2 0.0 5.1e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KPI34580.1 - 0.00021 21.2 4.4 0.26 11.3 0.6 2.4 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.15 KPI34580.1 - 0.39 10.7 5.6 7.3 6.6 0.5 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CorA PF01544.18 KPI34581.1 - 1.8e-38 132.5 0.0 4.5e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein REV PF00424.18 KPI34581.1 - 0.81 9.8 5.7 0.61 10.1 1.0 2.9 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Zip PF02535.22 KPI34582.1 - 4.6e-39 134.6 0.3 5.2e-39 134.4 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FSH1 PF03959.13 KPI34583.1 - 1.1e-43 149.4 0.0 1.6e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MFS_1 PF07690.16 KPI34585.1 - 4.5e-14 52.1 33.6 1.7e-10 40.4 20.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KPI34585.1 - 0.0037 15.6 0.6 0.0037 15.6 0.6 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Packaging_FI PF14000.6 KPI34586.1 - 0.017 15.5 1.3 0.017 15.5 1.3 1.7 2 0 0 2 2 2 0 DNA packaging protein FI p450 PF00067.22 KPI34587.1 - 5.9e-42 144.0 0.0 7.9e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KPI34588.1 - 3.6e-67 226.8 0.0 4.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI34588.1 - 1.4e-05 26.0 0.0 2.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TMEM52 PF14979.6 KPI34588.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Transmembrane 52 MFS_1 PF07690.16 KPI34589.1 - 2.7e-16 59.5 43.5 3.2e-16 59.2 36.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI34589.1 - 3.2e-07 29.6 6.6 3.2e-07 29.6 6.6 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Mpv17_PMP22 PF04117.12 KPI34590.1 - 2.4e-20 72.5 0.1 5.9e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3176 PF11374.8 KPI34593.1 - 1.2e-17 64.1 2.1 2.3e-17 63.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) bZIP_1 PF00170.21 KPI34594.1 - 1.6e-07 31.3 11.4 1.6e-07 31.3 11.4 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KPI34594.1 - 0.0016 18.5 11.6 0.0016 18.5 11.6 3.3 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPI34594.1 - 0.02 15.4 14.1 0.02 15.4 14.1 3.9 3 1 0 4 4 4 0 bZIP Maf transcription factor NinB PF05772.12 KPI34594.1 - 0.032 14.0 0.4 0.082 12.7 0.4 1.6 1 0 0 1 1 1 0 NinB protein DUF4775 PF16001.5 KPI34594.1 - 0.23 10.8 2.6 0.38 10.1 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Fungal_trans PF04082.18 KPI34595.1 - 1.8e-14 53.4 0.1 2.8e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3176 PF11374.8 KPI34596.1 - 8.3e-17 61.3 5.1 1.1e-16 60.9 2.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) ECF_trnsprt PF12822.7 KPI34596.1 - 0.16 12.0 2.9 1.2 9.2 1.2 2.2 2 0 0 2 2 2 0 ECF transporter, substrate-specific component DUF4064 PF13273.6 KPI34596.1 - 0.53 10.6 5.6 1.9 8.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF3808 PF10300.9 KPI34597.1 - 2.2e-135 452.1 0.0 3.3e-135 451.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.13 KPI34599.1 - 3.5e-07 30.2 0.6 1.2e-05 25.2 0.1 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family Bac_rhamnosid6H PF17389.2 KPI34600.1 - 1.5e-12 47.5 0.0 5.3e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain FF PF01846.19 KPI34601.1 - 1.9e-52 175.2 21.0 7.4e-15 54.9 1.2 6.7 6 0 0 6 6 6 6 FF domain WW PF00397.26 KPI34601.1 - 1.1e-07 31.8 2.2 2.7e-07 30.6 2.2 1.7 1 0 0 1 1 1 1 WW domain F-box-like PF12937.7 KPI34602.1 - 1.4e-05 24.9 0.1 2.8e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI34602.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Glyco_trans_2_3 PF13632.6 KPI34603.1 - 2.4e-51 174.5 2.0 2.4e-51 174.5 2.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPI34603.1 - 1.4e-06 28.4 0.2 7.4e-05 22.7 0.1 2.5 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI34603.1 - 1.5e-06 28.2 0.0 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPI34603.1 - 0.00083 18.9 0.0 0.0039 16.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sugar_tr PF00083.24 KPI34604.1 - 8.7e-105 351.2 18.8 9.8e-105 351.0 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34604.1 - 1.5e-30 106.3 23.0 1.5e-30 106.3 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPI34604.1 - 3.3e-05 22.7 14.0 4.6e-05 22.2 0.4 2.6 3 1 0 3 3 3 2 MFS/sugar transport protein DUF1218 PF06749.12 KPI34604.1 - 0.92 10.1 0.1 0.92 10.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) ETRAMP PF09716.10 KPI34604.1 - 1.8 8.7 4.9 4.9 7.3 0.2 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Nup160 PF11715.8 KPI34605.1 - 4.5e-67 226.9 0.1 1.2e-66 225.5 0.1 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 AKAP95 PF04988.12 KPI34605.1 - 0.22 11.8 0.0 0.45 10.7 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) MR_MLE_C PF13378.6 KPI34606.1 - 8.3e-50 169.4 0.0 1.2e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI34606.1 - 9.7e-06 25.8 0.0 7.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_16 PF00722.21 KPI34607.1 - 2.5e-17 62.9 0.0 6e-17 61.7 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Acetyltransf_1 PF00583.25 KPI34609.1 - 1.8e-13 50.7 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI34609.1 - 9.6e-10 38.8 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI34609.1 - 2.8e-09 37.0 0.0 3.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPI34609.1 - 0.00038 20.6 0.0 0.00046 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI34609.1 - 0.00084 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KPI34609.1 - 0.0082 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein S1-P1_nuclease PF02265.16 KPI34611.1 - 3e-55 187.8 0.1 8.4e-55 186.3 0.1 1.6 1 1 0 1 1 1 1 S1/P1 Nuclease ELFV_dehydrog PF00208.21 KPI34612.1 - 2.6e-83 279.5 6.6 3.2e-83 279.2 6.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KPI34612.1 - 3.5e-48 162.8 0.0 8.6e-48 161.5 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.10 KPI34612.1 - 0.0034 17.2 0.5 0.015 15.1 0.2 2.1 1 1 1 2 2 2 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV AlaDh_PNT_C PF01262.21 KPI34612.1 - 0.03 13.6 1.6 0.13 11.6 0.5 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FTCD_C PF04961.12 KPI34612.1 - 0.051 13.4 2.0 5.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase NAD_binding_7 PF13241.6 KPI34612.1 - 0.16 12.4 0.1 0.4 11.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding PGK PF00162.19 KPI34613.1 - 1.2e-152 508.3 2.8 1.3e-152 508.1 2.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KPI34613.1 - 0.0012 18.8 0.9 0.065 13.3 0.0 3.1 3 0 0 3 3 3 1 PA domain Pyr_redox PF00070.27 KPI34613.1 - 0.31 11.6 1.9 15 6.2 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1798 PF08807.10 KPI34614.1 - 0.039 14.1 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Fungal_trans_2 PF11951.8 KPI34616.1 - 1.8e-05 23.7 0.1 3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_6 PF08030.12 KPI34617.1 - 8.4e-20 71.5 0.0 1e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KPI34617.1 - 0.081 13.6 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Sel1 PF08238.12 KPI34618.1 - 1.1e-13 51.4 5.2 0.00011 22.8 0.0 3.9 5 0 0 5 5 5 3 Sel1 repeat Adeno_E1A PF02703.14 KPI34618.1 - 2.9 7.4 6.9 4.6 6.8 6.9 1.2 1 0 0 1 1 1 0 Early E1A protein zf-CCCH PF00642.24 KPI34619.1 - 0.00091 19.1 0.1 0.00091 19.1 0.1 4.2 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KPI34619.1 - 0.0026 18.5 15.7 0.11 13.2 0.7 3.2 1 1 2 3 3 3 3 Torus domain DUF1479 PF07350.12 KPI34620.1 - 2.7e-92 309.7 0.0 3.3e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) zf-MYND PF01753.18 KPI34621.1 - 8.2e-09 35.4 9.0 1.6e-08 34.5 9.0 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KPI34621.1 - 0.14 12.0 6.9 0.31 10.9 6.9 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KPI34621.1 - 0.28 11.5 9.2 0.58 10.5 9.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Trs65 PF12735.7 KPI34623.1 - 6.7e-64 216.3 1.5 1e-63 215.7 1.5 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Aldo_ket_red PF00248.21 KPI34624.1 - 4.5e-53 180.4 0.0 5.7e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIF_beta PF02270.15 KPI34625.1 - 8e-25 86.8 0.6 1.4e-24 86.0 0.6 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KPI34625.1 - 4.7e-23 82.4 0.7 1.1e-22 81.2 0.0 1.9 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KPI34625.1 - 0.00018 22.3 1.3 0.0004 21.2 1.3 1.7 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Aldolase_II PF00596.21 KPI34626.1 - 5.7e-43 147.0 0.0 6.9e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Spc24 PF08286.11 KPI34627.1 - 2e-30 105.1 0.0 1.7e-29 102.1 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 SlyX PF04102.12 KPI34627.1 - 0.037 14.6 2.7 3 8.5 0.7 2.3 2 0 0 2 2 2 0 SlyX GAS PF13851.6 KPI34627.1 - 0.13 11.6 2.0 0.25 10.7 1.2 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.13 KPI34627.1 - 0.14 12.6 2.7 3.2 8.3 0.9 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 KPI34627.1 - 0.15 12.7 2.4 0.38 11.4 1.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA MerR-DNA-bind PF09278.11 KPI34627.1 - 0.19 12.3 6.7 0.85 10.2 0.8 3.2 3 0 0 3 3 3 0 MerR, DNA binding Jnk-SapK_ap_N PF09744.9 KPI34627.1 - 1.9 8.7 7.5 4.9 7.4 0.2 2.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Nup54 PF13874.6 KPI34627.1 - 4 7.5 7.8 22 5.1 7.8 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 MFS_1 PF07690.16 KPI34628.1 - 1.9e-29 102.7 38.5 2e-29 102.6 37.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.8 KPI34628.1 - 0.061 12.8 0.3 4.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HbrB PF08539.11 KPI34629.1 - 1.7e-38 132.3 0.0 5.3e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 HbrB-like Epiglycanin_C PF14654.6 KPI34630.1 - 0.0097 16.0 0.0 0.055 13.5 0.1 2.0 2 0 0 2 2 2 1 Mucin, catalytic, TM and cytoplasmic tail region VSP PF03302.13 KPI34630.1 - 0.033 13.0 1.2 0.058 12.2 1.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 KPI34630.1 - 0.047 13.1 0.7 0.11 11.9 0.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KPI34630.1 - 0.065 14.1 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD99L2 PF12301.8 KPI34630.1 - 0.077 13.3 0.3 0.19 12.0 0.3 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 Trp_oprn_chp PF09534.10 KPI34630.1 - 0.22 11.3 6.0 0.042 13.6 1.1 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TPPK_C PF12555.8 KPI34630.1 - 0.66 10.1 3.2 1.2 9.2 3.2 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal MGC-24 PF05283.11 KPI34630.1 - 5.3 7.5 7.6 1.1 9.7 0.5 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GMC_oxred_N PF00732.19 KPI34631.1 - 5.9e-59 199.9 0.0 9e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI34631.1 - 6.7e-26 91.5 0.0 1.4e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 KPI34631.1 - 1.5e-25 89.9 39.4 2.7e-25 89.1 39.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KPI34631.1 - 1.5e-21 77.1 0.5 3.4e-19 69.3 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KPI34631.1 - 7.8e-12 44.9 0.1 2e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI34631.1 - 4e-10 39.4 1.2 0.0086 15.3 0.2 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI34631.1 - 1.5e-09 38.0 4.3 0.00039 20.6 0.4 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI34631.1 - 4.7e-09 36.3 10.2 0.021 14.4 0.1 3.6 2 1 1 3 3 3 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI34631.1 - 7.6e-08 31.9 6.0 0.0029 16.8 1.3 3.3 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 KPI34631.1 - 1.4e-07 30.6 4.7 0.081 11.6 0.9 4.1 4 0 0 4 4 4 2 HI0933-like protein Pyr_redox PF00070.27 KPI34631.1 - 5.1e-07 30.2 0.9 0.73 10.4 0.1 3.6 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI34631.1 - 8.2e-06 25.2 0.6 0.0038 16.5 0.0 2.5 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.24 KPI34631.1 - 0.025 13.9 2.0 0.86 8.8 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KPI34631.1 - 0.29 10.3 2.5 14 4.9 0.4 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI34631.1 - 0.45 9.3 2.2 3.6 6.3 0.0 2.7 2 1 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 KPI34631.1 - 7 5.6 6.6 14 4.7 3.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KPI34632.1 - 2.7e-48 164.7 0.5 3.5e-48 164.3 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI34632.1 - 7.1e-18 64.9 0.1 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI34632.1 - 4.1e-16 59.3 0.2 5e-14 52.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPI34632.1 - 2.9e-05 24.4 0.1 0.0042 17.5 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KPI34632.1 - 0.00013 21.2 0.1 0.09 11.9 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPI34632.1 - 0.00026 20.3 0.1 0.0016 17.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KPI34632.1 - 0.00036 20.7 1.3 0.055 13.7 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI34632.1 - 0.0013 18.1 0.3 0.27 10.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPI34632.1 - 0.0078 15.5 1.0 2.8 7.1 0.0 3.0 2 1 1 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 KPI34632.1 - 0.024 13.7 7.1 1.8 7.5 0.2 4.0 2 2 3 5 5 5 0 FAD binding domain DAO PF01266.24 KPI34632.1 - 0.034 13.7 8.1 3.2 7.3 0.0 3.8 2 2 2 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 KPI34632.1 - 0.035 13.2 5.6 4.4 6.3 0.2 4.1 4 1 1 5 5 5 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KPI34632.1 - 0.07 13.2 0.1 19 5.3 0.0 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Calreticulin PF00262.18 KPI34633.1 - 2.3e-168 559.8 15.3 2.9e-168 559.4 15.3 1.1 1 0 0 1 1 1 1 Calreticulin family DAO PF01266.24 KPI34634.1 - 4.3e-37 128.5 0.9 5e-37 128.3 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI34634.1 - 3.3e-08 33.6 0.5 1.1e-06 28.8 0.0 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI34634.1 - 2.1e-06 27.1 1.8 2.6e-05 23.5 1.8 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI34634.1 - 2.8e-05 23.5 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI34634.1 - 0.00083 18.5 0.0 0.7 8.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A TrkA_N PF02254.18 KPI34634.1 - 0.0013 19.0 0.0 0.0034 17.6 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 KPI34634.1 - 0.0013 19.2 0.0 0.0036 17.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KPI34634.1 - 0.0033 16.9 0.6 0.84 9.0 0.0 2.6 2 1 1 3 3 3 2 GMC oxidoreductase Pyr_redox_3 PF13738.6 KPI34634.1 - 0.0094 15.2 0.0 0.067 12.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KPI34634.1 - 0.012 15.9 0.1 0.56 10.5 0.0 2.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 KPI34634.1 - 0.012 15.6 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPI34634.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KPI34634.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KPI34634.1 - 0.21 10.9 0.1 0.64 9.3 0.0 1.7 2 0 0 2 2 2 0 ThiF family HEM4 PF02602.15 KPI34635.1 - 1.1e-31 109.9 0.0 3.4e-15 56.1 0.0 2.5 1 1 0 2 2 2 2 Uroporphyrinogen-III synthase HemD HAD_2 PF13419.6 KPI34636.1 - 0.12 12.5 0.0 6.5 6.8 0.0 2.6 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KPI34637.1 - 9.7e-15 54.3 36.4 4.6e-14 52.1 17.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Aldedh PF00171.22 KPI34638.1 - 2.1e-136 455.1 0.2 2.7e-136 454.8 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_cyclohydro2 PF00925.20 KPI34638.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II DUF3425 PF11905.8 KPI34639.1 - 9.6e-11 41.7 3.3 1e-09 38.4 3.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI34639.1 - 0.014 15.5 2.1 0.025 14.7 2.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor ABC_tran_CTD PF16326.5 KPI34640.1 - 0.0086 16.3 4.4 1.6 9.0 0.6 2.9 3 0 0 3 3 3 2 ABC transporter C-terminal domain GCN5L1 PF06320.13 KPI34640.1 - 0.014 15.5 1.3 0.031 14.4 0.5 2.0 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Tektin PF03148.14 KPI34640.1 - 0.04 12.7 2.9 0.046 12.5 0.3 2.2 3 0 0 3 3 3 0 Tektin family T6PP_N PF18572.1 KPI34640.1 - 0.16 11.8 0.3 0.46 10.4 0.1 1.9 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain BLOC1_2 PF10046.9 KPI34640.1 - 0.19 12.0 1.5 28 5.1 0.1 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KPI34640.1 - 0.4 10.8 3.9 0.18 11.9 0.8 1.8 2 0 0 2 2 2 0 Tropomyosin like Rx_N PF18052.1 KPI34640.1 - 0.43 10.9 3.5 2.2 8.6 0.6 2.8 1 1 1 2 2 2 0 Rx N-terminal domain Seryl_tRNA_N PF02403.22 KPI34640.1 - 0.45 10.8 4.5 1.6 9.0 1.9 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.6 KPI34640.1 - 0.68 10.3 14.2 12 6.3 0.3 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) Smoothelin PF12510.8 KPI34640.1 - 1.8 8.6 6.5 0.36 10.9 0.5 2.6 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein BLACT_WH PF17778.1 KPI34642.1 - 1.1e-17 63.7 0.1 1.8e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Gon7 PF08738.10 KPI34644.1 - 0.00091 19.3 13.2 0.0035 17.4 5.3 2.1 1 1 1 2 2 2 2 Gon7 family MFS_1 PF07690.16 KPI34645.1 - 2.5e-30 105.6 25.1 2.5e-30 105.6 25.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SPX PF03105.19 KPI34646.1 - 0.16 11.8 11.9 0.17 11.8 11.9 1.1 1 0 0 1 1 1 0 SPX domain FUSC PF04632.12 KPI34646.1 - 1.1 7.7 9.7 1.3 7.5 9.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mitofilin PF09731.9 KPI34646.1 - 1.1 8.0 13.3 1.5 7.6 13.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.13 KPI34646.1 - 1.2 9.0 20.9 1.4 8.9 20.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.21 KPI34647.1 - 5.4e-20 71.4 1.4 1.4e-13 50.8 0.2 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KPI34647.1 - 2.9e-05 23.5 0.1 0.00019 20.9 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA LRR_4 PF12799.7 KPI34648.1 - 1.3e-12 47.7 12.8 0.086 13.3 0.3 7.3 4 1 6 10 10 10 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KPI34648.1 - 3.8e-10 39.5 0.4 1.5e-09 37.6 0.4 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KPI34648.1 - 1e-06 28.3 23.0 7.5 6.9 0.3 11.6 13 0 0 13 13 13 2 Leucine Rich repeat F-box PF00646.33 KPI34648.1 - 3.7e-05 23.5 0.0 0.00015 21.6 0.0 2.2 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 KPI34648.1 - 0.00039 20.1 4.3 4.6 7.1 0.2 5.3 4 1 1 5 5 5 2 Leucine rich repeat Recep_L_domain PF01030.24 KPI34648.1 - 0.024 14.7 0.1 2.8 8.1 0.0 3.7 1 1 3 4 4 4 0 Receptor L domain AA_permease_2 PF13520.6 KPI34649.1 - 1.4e-62 211.9 56.8 1.8e-62 211.6 56.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI34649.1 - 1.1e-13 50.6 47.4 1.4e-13 50.3 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease NMO PF03060.15 KPI34650.1 - 1.2e-54 186.0 1.0 1.6e-54 185.5 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI34650.1 - 3.7e-10 39.4 0.4 4.6e-08 32.4 0.2 2.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPI34650.1 - 2.7e-05 23.3 3.1 2.7e-05 23.3 3.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPI34650.1 - 0.00026 20.2 0.1 0.00046 19.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KPI34650.1 - 0.016 14.4 0.4 0.031 13.5 0.4 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase YjeF_N PF03853.15 KPI34650.1 - 0.047 13.6 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus Catalase PF00199.19 KPI34651.1 - 2.2e-168 560.3 0.3 3.1e-168 559.8 0.3 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KPI34651.1 - 6.6e-15 55.1 0.0 1.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KPI34651.1 - 4.2e-09 36.2 0.2 1.2e-08 34.7 0.2 1.9 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KPI34651.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family HbrB PF08539.11 KPI34653.1 - 1.1e-05 25.4 0.2 1.1e-05 25.4 0.2 1.8 2 1 0 2 2 2 1 HbrB-like AA_permease PF00324.21 KPI34654.1 - 9.2e-75 252.0 41.7 4.4e-66 223.4 29.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KPI34654.1 - 7.1e-20 71.2 41.8 2.2e-18 66.3 30.5 2.1 1 1 1 2 2 2 2 Amino acid permease Zn_clus PF00172.18 KPI34655.1 - 5.1e-07 29.7 6.8 1.1e-06 28.7 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KPI34655.1 - 0.015 15.0 0.5 0.036 13.8 0.5 1.7 1 0 0 1 1 1 0 Integrin plexin domain Cytochrom_B562 PF07361.11 KPI34655.1 - 0.24 12.1 0.0 0.47 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 adh_short PF00106.25 KPI34656.1 - 2e-33 115.5 0.0 2.5e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34656.1 - 7.3e-27 94.4 0.0 1e-26 94.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34656.1 - 0.0018 18.2 0.2 0.005 16.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPI34656.1 - 0.086 12.3 0.1 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Mak10 PF04112.13 KPI34656.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Vps39_1 PF10366.9 KPI34657.1 - 2.6e-32 111.3 0.1 3.1e-29 101.4 0.0 3.2 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KPI34657.1 - 5.4e-30 104.0 0.0 4.5e-29 101.1 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KPI34657.1 - 6.8e-16 58.7 0.0 2.2e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KPI34657.1 - 5e-09 36.2 8.1 1.4e-07 31.5 3.3 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_1 PF00515.28 KPI34657.1 - 0.06 13.2 1.1 1.4 8.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPI34657.1 - 0.33 11.5 4.0 3.6 8.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_4 PF08386.10 KPI34658.1 - 2e-22 79.2 0.0 4.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KPI34658.1 - 2e-17 63.7 0.2 9.9e-15 54.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KPI34658.1 - 0.052 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Fis1_TPR_C PF14853.6 KPI34659.1 - 3.2e-27 94.4 1.5 4.6e-27 93.8 1.5 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KPI34659.1 - 9.4e-18 63.6 0.1 1.5e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KPI34659.1 - 0.0019 18.2 2.5 0.0019 18.2 2.5 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPI34659.1 - 0.045 14.4 0.3 0.1 13.3 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat RSB_motif PF16294.5 KPI34659.1 - 0.084 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Abhydrolase_3 PF07859.13 KPI34660.1 - 1.3e-34 119.9 0.0 3.3e-25 89.2 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold zf-RING_2 PF13639.6 KPI34660.1 - 2.4e-12 47.0 8.1 2.4e-12 47.0 8.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KPI34660.1 - 2.1e-10 40.2 6.2 3.6e-10 39.4 2.9 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPI34660.1 - 1.3e-08 34.5 7.4 1.3e-08 34.5 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI34660.1 - 3.2e-08 33.3 11.2 1.5e-07 31.1 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI34660.1 - 1.7e-06 27.7 7.2 1.7e-06 27.7 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPI34660.1 - 1e-05 25.7 7.3 1e-05 25.7 7.3 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPI34660.1 - 0.00044 20.2 5.5 0.00044 20.2 5.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI34660.1 - 0.00086 19.3 2.4 0.00086 19.3 2.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zinc_ribbon_9 PF14369.6 KPI34660.1 - 0.0013 18.9 4.0 0.0013 18.9 4.0 3.0 3 0 0 3 3 2 1 zinc-ribbon zf-ANAPC11 PF12861.7 KPI34660.1 - 0.0032 17.5 3.0 0.0084 16.1 3.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KPI34660.1 - 0.0051 16.8 0.6 0.0051 16.8 0.6 2.7 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KPI34660.1 - 0.0068 15.9 0.6 0.019 14.5 0.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Prok-RING_4 PF14447.6 KPI34660.1 - 0.037 13.9 14.7 0.03 14.2 7.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KPI34660.1 - 0.086 13.0 7.8 0.95 9.7 7.8 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KPI34660.1 - 0.098 12.8 10.3 3.9 7.7 0.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 KPI34660.1 - 0.12 12.4 1.3 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zinc-ribbons_6 PF07191.12 KPI34660.1 - 0.13 12.3 7.8 1.2 9.1 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbons Say1_Mug180 PF10340.9 KPI34660.1 - 0.28 10.0 0.0 0.43 9.4 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase zf-UDP PF14569.6 KPI34660.1 - 0.32 11.1 3.2 18 5.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 KPI34660.1 - 0.35 10.9 7.6 4.1 7.5 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon Trm112p PF03966.16 KPI34660.1 - 0.48 11.0 1.6 6.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Trm112p-like protein Zn-ribbon_8 PF09723.10 KPI34660.1 - 1.7 8.9 8.1 3 8.0 1.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_17 PF17120.5 KPI34660.1 - 4.9 6.9 15.9 0.18 11.4 8.0 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KPI34660.1 - 7.4 6.5 12.9 0.76 9.6 3.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Abhydrolase_6 PF12697.7 KPI34661.1 - 5.9e-12 46.6 0.6 8.8e-12 46.1 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI34661.1 - 1.2e-08 34.9 0.0 5.3e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI34661.1 - 2.3e-08 33.6 0.0 0.00082 18.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPI34661.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 KPI34661.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family S4 PF01479.25 KPI34663.1 - 5.2e-16 58.1 0.0 9.4e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KPI34663.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain Peptidase_S64 PF08192.11 KPI34663.1 - 3.3 6.1 5.3 4.5 5.6 5.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 K_trans PF02705.16 KPI34664.1 - 2.4e-173 577.5 18.2 3.1e-173 577.1 18.2 1.1 1 0 0 1 1 1 1 K+ potassium transporter FAD_binding_3 PF01494.19 KPI34665.1 - 6.2e-18 65.2 0.1 2.1e-09 37.1 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI34665.1 - 0.18 12.0 0.2 0.42 10.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34665.1 - 0.27 10.4 0.6 6.7 5.9 0.3 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ARHGEF5_35 PF15441.6 KPI34666.1 - 9.2 5.1 8.8 11 4.8 8.8 1.0 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 HATPase_c PF02518.26 KPI34667.1 - 5.5e-19 68.7 0.1 1.3e-18 67.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI34667.1 - 2.5e-14 53.4 0.1 4.7e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KPI34667.1 - 1.1e-12 47.8 0.0 5.4e-12 45.6 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.24 KPI34668.1 - 1.1e-113 380.5 28.5 2.5e-113 379.3 28.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34668.1 - 1.6e-24 86.5 54.9 5e-15 55.3 23.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoU_methylas_C PF12105.8 KPI34668.1 - 0.039 13.7 0.4 0.077 12.7 0.4 1.4 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal p450 PF00067.22 KPI34669.1 - 1.7e-61 208.4 0.0 2.2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_130 PF04041.13 KPI34670.1 - 4.3e-32 111.3 0.0 7.1e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 KPI34670.1 - 8.1e-07 28.9 0.0 7.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KPI34670.1 - 0.00076 18.9 0.4 0.017 14.5 0.1 2.7 2 1 0 3 3 3 1 Glycosyl hydrolases family 43 BNR_3 PF13859.6 KPI34670.1 - 0.068 12.4 0.7 0.31 10.3 0.4 1.9 1 1 1 2 2 2 0 BNR repeat-like domain TRI12 PF06609.13 KPI34672.1 - 1.4e-47 162.5 22.7 1.8e-47 162.1 22.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI34672.1 - 2.1e-25 89.4 48.6 2.6e-25 89.1 43.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI34672.1 - 8.4e-09 34.8 16.1 8.4e-09 34.8 16.1 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter DUF3522 PF12036.8 KPI34672.1 - 0.074 13.3 0.4 0.074 13.3 0.4 3.2 4 1 0 5 5 5 0 Protein of unknown function (DUF3522) Oxidored_FMN PF00724.20 KPI34673.1 - 2.3e-18 66.6 0.0 2.7e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3242 PF11586.8 KPI34673.1 - 0.038 13.7 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) PAN_1 PF00024.26 KPI34674.1 - 0.00021 21.2 1.1 0.00033 20.6 1.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KPI34674.1 - 0.013 15.4 0.8 0.022 14.7 0.8 1.4 1 0 0 1 1 1 0 PAN domain EthD PF07110.11 KPI34675.1 - 1.4e-07 32.6 0.0 1.7e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 EthD domain p450 PF00067.22 KPI34676.1 - 3.9e-65 220.4 0.0 4.8e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4083 PF13314.6 KPI34676.1 - 0.43 10.6 1.7 0.89 9.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Aldo_ket_red PF00248.21 KPI34678.1 - 1.2e-47 162.5 0.0 8e-47 159.8 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Btz PF09405.10 KPI34678.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding IF2_N PF04760.15 KPI34678.1 - 0.17 11.7 0.1 0.73 9.7 0.0 2.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region PAN_1 PF00024.26 KPI34679.1 - 3.5e-07 30.1 0.1 0.024 14.6 0.1 2.2 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 KPI34679.1 - 0.033 14.1 3.4 0.96 9.4 0.1 2.6 2 0 0 2 2 2 0 PAN domain TrkH PF02386.16 KPI34680.1 - 2.2e-96 323.3 4.7 1.2e-91 307.7 0.3 2.1 2 0 0 2 2 2 2 Cation transport protein Fungal_trans_2 PF11951.8 KPI34681.1 - 4.1e-06 25.8 1.3 0.024 13.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KPI34682.1 - 8.6e-18 64.7 0.1 3.8e-10 39.5 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI34682.1 - 4.7e-06 26.4 0.1 8.3e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI34682.1 - 3.5e-05 23.9 0.1 0.00011 22.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34682.1 - 0.0014 17.9 0.4 0.0065 15.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI34682.1 - 0.0059 15.7 0.1 0.0089 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KPI34682.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KPI34682.1 - 0.014 16.0 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KPI34682.1 - 0.017 15.7 0.1 0.042 14.4 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.6 KPI34682.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI34682.1 - 0.054 12.5 0.1 0.38 9.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KPI34682.1 - 0.091 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KPI34682.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KPI34682.1 - 0.13 12.3 0.1 0.71 9.9 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 KPI34682.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KPI34682.1 - 0.2 11.9 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KPI34682.1 - 0.21 10.2 0.1 0.46 9.1 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KPI34682.1 - 0.25 10.4 0.1 0.67 9.0 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Chromo PF00385.24 KPI34683.1 - 0.00047 20.0 1.1 0.001 18.9 1.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S15 PF02129.18 KPI34684.1 - 1.3e-44 152.8 1.7 9.4e-41 140.2 0.3 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KPI34684.1 - 5e-34 118.2 0.1 7.6e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 KPI34684.1 - 0.003 17.1 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family MBD PF01429.19 KPI34684.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain PP2C PF00481.21 KPI34685.1 - 1.9e-36 126.0 0.0 6.2e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Fungal_trans PF04082.18 KPI34688.1 - 1.7e-10 40.4 0.0 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDP-OH_P_transf PF01066.21 KPI34689.1 - 3.4e-14 53.4 0.5 3.4e-14 53.4 0.5 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_zinc_N PF00107.26 KPI34690.1 - 1.6e-09 37.8 0.1 3.9e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI34690.1 - 7.5e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Oxidored_FMN PF00724.20 KPI34691.1 - 4.1e-30 105.2 0.0 2.8e-29 102.5 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 KPI34691.1 - 1.9e-16 59.9 0.3 2.8e-16 59.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_1 PF00300.22 KPI34693.1 - 4e-11 43.0 0.1 1.1e-10 41.5 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Biotin_carb_C PF02785.19 KPI34696.1 - 3.2e-36 123.7 0.0 6.9e-36 122.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KPI34696.1 - 1e-15 57.8 0.0 2.3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_lipoyl PF00364.22 KPI34696.1 - 1.1e-13 50.8 0.8 3.3e-13 49.3 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KPI34696.1 - 3.6e-05 23.5 0.6 0.025 14.4 0.0 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like RnfC_N PF13375.6 KPI34696.1 - 0.00049 20.0 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain LAL_C2 PF18603.1 KPI34696.1 - 0.053 13.7 0.1 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 DUF2118 PF09891.9 KPI34696.1 - 0.061 13.3 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) bZIP_1 PF00170.21 KPI34697.1 - 0.00011 22.3 16.4 0.00016 21.7 16.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor FH2 PF02181.23 KPI34697.1 - 0.0031 16.7 0.8 0.0039 16.4 0.8 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain GAS PF13851.6 KPI34697.1 - 0.1 11.9 9.1 0.15 11.4 9.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KPI34697.1 - 0.12 11.7 2.5 0.16 11.3 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glutaredoxin2_C PF04399.13 KPI34697.1 - 0.15 11.9 1.2 0.25 11.2 1.2 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain OmpH PF03938.14 KPI34697.1 - 0.26 11.6 9.6 0.43 10.9 9.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.17 KPI34697.1 - 0.31 11.6 13.5 0.62 10.6 13.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.19 KPI34697.1 - 0.32 8.9 3.8 0.37 8.6 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAS20 PF02064.15 KPI34697.1 - 0.92 9.6 6.1 1.6 8.9 6.1 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor bZIP_2 PF07716.15 KPI34697.1 - 2.8 8.1 17.4 5.6 7.1 17.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF1682 PF07946.14 KPI34697.1 - 9.9 5.3 11.3 14 4.8 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PdxA PF04166.12 KPI34698.1 - 4.4e-76 256.0 0.0 5.5e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Septin PF00735.18 KPI34699.1 - 2.3e-119 397.9 0.1 2.3e-119 397.9 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KPI34699.1 - 2.3e-08 34.1 0.7 5.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI34699.1 - 1.5e-05 24.6 1.5 0.0014 18.2 0.0 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KPI34699.1 - 0.00014 22.3 3.3 0.025 15.1 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 KPI34699.1 - 0.0016 18.8 0.2 0.0057 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPI34699.1 - 0.0027 17.6 0.7 0.0027 17.6 0.7 3.5 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KPI34699.1 - 0.0028 17.0 1.7 0.0038 16.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KPI34699.1 - 0.0029 17.8 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KPI34699.1 - 0.007 16.7 1.2 0.026 14.8 0.0 2.5 2 2 1 3 3 3 1 AAA domain Ras PF00071.22 KPI34699.1 - 0.011 15.3 0.0 0.05 13.2 0.0 2.1 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.6 KPI34699.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KPI34699.1 - 0.03 14.1 3.4 0.71 9.6 0.1 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KPI34699.1 - 0.033 14.3 8.7 1 9.4 0.0 3.6 3 1 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KPI34699.1 - 0.053 14.0 7.3 12 6.3 6.9 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI34699.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPI34699.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPI34699.1 - 0.11 12.9 1.3 0.85 10.0 0.0 2.6 3 0 0 3 3 2 0 RNA helicase Exonuc_VII_L PF02601.15 KPI34699.1 - 0.14 11.7 7.3 0.26 10.8 7.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 KPI34699.1 - 0.65 10.1 3.9 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_32 PF13654.6 KPI34699.1 - 1.7 7.4 14.1 2 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 KPI34699.1 - 2.6 7.0 8.0 4 6.4 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2937 PF11157.8 KPI34699.1 - 2.7 7.7 7.2 1.1 8.9 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Strep_SA_rep PF06696.11 KPI34699.1 - 3.5 7.7 5.1 0.42 10.7 0.6 1.8 2 0 0 2 2 1 0 Streptococcal surface antigen repeat DUF3987 PF13148.6 KPI34699.1 - 7.2 5.5 9.6 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MBOAT_2 PF13813.6 KPI34700.1 - 4.2e-14 52.6 0.7 4.2e-14 52.6 0.7 2.0 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Asp PF00026.23 KPI34701.1 - 1e-09 38.3 0.0 2.1e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Amnionless PF14828.6 KPI34701.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless CoatB PF10389.9 KPI34701.1 - 0.36 10.7 3.8 0.67 9.8 3.8 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B Dabb PF07876.12 KPI34702.1 - 2.2e-23 82.7 0.0 2.5e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ribosomal_S7 PF00177.21 KPI34703.1 - 2.4e-26 92.2 0.3 5.4e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Prominin PF05478.11 KPI34703.1 - 0.38 8.6 0.2 0.53 8.2 0.2 1.1 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.16 KPI34704.1 - 4.3e-39 134.5 31.8 5.8e-39 134.0 31.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GDH_N PF12466.8 KPI34704.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal UDPG_MGDP_dh_N PF03721.14 KPI34705.1 - 6.4e-56 188.9 0.0 1.1e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KPI34705.1 - 3.4e-29 100.9 0.1 7.3e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KPI34705.1 - 1.5e-17 63.9 1.3 9.9e-13 48.4 0.1 4.2 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 KPI34705.1 - 0.0097 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KPI34705.1 - 0.038 14.1 0.1 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPI34705.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MTS PF05175.14 KPI34705.1 - 0.14 11.7 0.0 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain CLN3 PF02487.17 KPI34706.1 - 9.9e-151 502.3 1.1 1.3e-150 502.0 1.1 1.0 1 0 0 1 1 1 1 CLN3 protein Fungal_trans PF04082.18 KPI34707.1 - 6.5e-07 28.7 0.2 1.3e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI34707.1 - 4.8e-05 23.4 8.8 8.5e-05 22.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1325 PF07039.11 KPI34708.1 - 6.5e-18 65.1 0.1 1.2e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF2560 PF10834.8 KPI34708.1 - 0.061 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) DUF1989 PF09347.10 KPI34709.1 - 7e-62 208.0 0.0 1.2e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.29 KPI34709.1 - 8.2e-13 48.9 0.0 2.2e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KPI34709.1 - 4.3e-09 36.6 0.0 4.3e-09 36.6 0.0 2.8 4 0 0 4 4 4 1 BCS1 N terminal SET PF00856.28 KPI34709.1 - 2.2e-08 34.7 0.3 9.1e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 SET domain SelP_N PF04592.14 KPI34709.1 - 0.0068 15.8 1.1 0.013 14.9 1.1 1.4 1 0 0 1 1 1 1 Selenoprotein P, N terminal region AAA_16 PF13191.6 KPI34709.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.13 KPI34709.1 - 0.026 13.7 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain DUF4887 PF16228.5 KPI34709.1 - 0.063 13.5 8.5 0.14 12.3 8.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) AAA_33 PF13671.6 KPI34709.1 - 0.088 13.0 0.1 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KPI34709.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Pex14_N PF04695.13 KPI34709.1 - 3 8.5 10.9 12 6.6 10.9 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ADH_zinc_N PF00107.26 KPI34710.1 - 2e-07 31.0 0.0 4.6e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI34710.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI34710.1 - 0.00032 21.8 0.0 0.00063 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-oxoacid_dh PF00198.23 KPI34711.1 - 1.9e-74 250.0 0.1 2.4e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPI34711.1 - 5e-17 61.5 0.9 1.1e-16 60.4 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Mito_carr PF00153.27 KPI34713.1 - 2.4e-59 197.3 4.2 2.3e-19 69.1 0.5 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein MGC-24 PF05283.11 KPI34713.1 - 0.32 11.4 1.9 0.48 10.9 1.1 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin L51_S25_CI-B8 PF05047.16 KPI34715.1 - 1.8e-05 24.6 0.1 4.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MCLC PF05934.11 KPI34715.1 - 1.7 7.2 5.5 3.1 6.4 5.5 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Sec7 PF01369.20 KPI34716.1 - 7.1e-45 152.9 9.8 5.1e-30 104.5 0.4 4.2 4 1 1 5 5 5 2 Sec7 domain Sec7_N PF12783.7 KPI34716.1 - 8.6e-40 136.2 3.2 8.6e-40 136.2 3.2 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KPI34716.1 - 1.6e-34 117.6 8.7 1.1e-33 114.9 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 KPI34716.1 - 2.9e-17 62.9 3.9 2.8e-16 59.7 0.4 3.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 BING4CT PF08149.11 KPI34717.1 - 1.3e-39 133.9 0.0 2e-35 120.4 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KPI34717.1 - 0.00022 21.5 0.0 4.9 7.5 0.0 4.7 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI34717.1 - 0.0011 19.7 0.0 0.69 10.9 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Mesd PF10185.9 KPI34717.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Pox_A_type_inc PF04508.12 KPI34718.1 - 0.00054 19.7 0.4 0.0016 18.2 0.4 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Shugoshin_N PF07558.11 KPI34718.1 - 0.012 15.5 0.3 0.03 14.2 0.3 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF2046 PF09755.9 KPI34718.1 - 0.082 12.1 4.0 0.3 10.3 0.7 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) SlyX PF04102.12 KPI34718.1 - 0.13 12.9 5.6 1.3 9.7 0.2 2.4 2 0 0 2 2 2 0 SlyX Atg14 PF10186.9 KPI34718.1 - 0.38 9.8 7.2 0.13 11.4 2.2 2.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KPI34718.1 - 2.9 7.7 4.3 0.8 9.5 0.2 1.9 2 0 0 2 2 2 0 Septum formation initiator Fe-S_biosyn PF01521.20 KPI34719.1 - 1.7e-19 70.0 0.0 2.2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pribosyltran_N PF13793.6 KPI34720.1 - 2.9e-43 146.5 0.1 2.4e-42 143.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KPI34720.1 - 1.6e-31 109.8 0.6 1.2e-27 97.2 0.2 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KPI34720.1 - 2.1e-07 30.6 0.3 0.0017 17.9 0.2 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain GTP_cyclohydro2 PF00925.20 KPI34721.1 - 9.9e-53 178.1 0.1 2.1e-46 157.5 0.2 3.4 2 1 0 2 2 2 2 GTP cyclohydrolase II CPSase_L_D2 PF02786.17 KPI34722.1 - 9.1e-17 61.2 0.1 1e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain cobW PF02492.19 KPI34724.1 - 2.6e-34 118.4 0.0 3.2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KPI34724.1 - 1.5e-05 24.1 0.1 0.013 14.5 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 KPI34724.1 - 0.022 14.5 0.0 6.5 6.4 0.0 2.4 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KPI34724.1 - 0.059 13.9 0.0 0.076 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KPI34724.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KPI34724.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein CbiA PF01656.23 KPI34724.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KPI34724.1 - 0.13 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA12 PF10443.9 KPI34724.1 - 0.27 9.9 0.0 0.48 9.1 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein NAD_binding_7 PF13241.6 KPI34725.1 - 1.9e-28 98.9 0.0 3.1e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KPI34725.1 - 8e-23 79.9 0.0 1.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KPI34725.1 - 1.9e-14 52.8 0.3 1.9e-14 52.8 0.3 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KPI34725.1 - 0.00026 20.3 0.0 0.00036 19.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI34725.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Na_Ca_ex PF01699.24 KPI34726.1 - 2.4e-47 160.7 33.9 2.2e-24 86.1 14.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CDRT4 PF15213.6 KPI34726.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein TPT PF03151.16 KPI34727.1 - 6.9e-35 120.8 16.7 9.2e-35 120.4 16.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KPI34727.1 - 3.3e-12 46.2 21.0 3.7e-12 46.1 20.3 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KPI34727.1 - 7.2e-05 23.0 41.5 0.00025 21.2 11.4 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF3185 PF11381.8 KPI34727.1 - 4.7 7.3 9.7 34 4.6 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) RIBIOP_C PF04950.12 KPI34728.1 - 1e-71 241.7 0.0 2.8e-71 240.3 0.0 1.7 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KPI34728.1 - 2.1e-18 66.2 0.0 4.7e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Aminotran_3 PF00202.21 KPI34729.1 - 3.8e-80 269.5 0.2 1.2e-58 198.7 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-III PMI_typeI PF01238.21 KPI34730.1 - 6.3e-133 443.6 0.0 7.4e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cu_amine_oxid PF01179.20 KPI34731.1 - 3e-161 536.9 0.0 3.6e-161 536.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KPI34731.1 - 3e-06 27.4 0.0 6.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MR_MLE_C PF13378.6 KPI34732.1 - 1.3e-51 175.3 0.2 1.7e-51 174.9 0.2 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI34732.1 - 8.3e-20 71.1 0.0 2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Abhydrolase_4 PF08386.10 KPI34734.1 - 1.9e-21 76.1 0.0 3.4e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KPI34734.1 - 5.9e-14 52.3 0.0 3.5e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.25 KPI34735.1 - 8.7e-19 67.7 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34735.1 - 2.9e-10 40.1 0.0 4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPI34735.1 - 8.6e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPI34735.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Methyltransf_24 PF13578.6 KPI34735.1 - 0.1 13.6 0.0 0.21 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain K_trans PF02705.16 KPI34736.1 - 4.1e-173 576.7 17.9 5.4e-173 576.3 17.9 1.1 1 0 0 1 1 1 1 K+ potassium transporter AIG2_2 PF13772.6 KPI34738.1 - 2.8e-07 30.8 0.1 4.4e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KPI34738.1 - 0.0015 19.1 0.0 0.0021 18.7 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF943 PF06092.12 KPI34738.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Sugar_tr PF00083.24 KPI34739.1 - 6.6e-62 209.8 18.5 7.7e-62 209.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34739.1 - 5.5e-22 78.2 26.4 5.5e-22 78.2 26.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KPI34739.1 - 6.8e-07 28.2 15.2 7.4e-06 24.8 3.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3328 PF11807.8 KPI34740.1 - 3.4e-20 72.8 0.0 7.2e-20 71.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CoA_transf_3 PF02515.17 KPI34741.1 - 3.8e-40 138.2 0.0 1.6e-33 116.3 0.0 2.6 2 1 0 2 2 2 2 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 KPI34742.1 - 1.7e-36 125.6 1.0 2.4e-36 125.2 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI34742.1 - 4.3e-24 84.5 0.1 7.5e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI34742.1 - 3.2e-13 50.3 0.0 3.5e-12 47.0 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPI34742.1 - 9.3e-07 29.2 0.1 1.4e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ABC2_membrane PF01061.24 KPI34744.1 - 5.2e-84 280.9 47.0 3.7e-43 147.4 15.3 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KPI34744.1 - 2.1e-28 99.6 0.0 2e-14 54.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPI34744.1 - 6.1e-24 83.8 14.6 3.1e-23 81.5 0.0 3.7 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KPI34744.1 - 2.9e-09 37.4 0.1 7.6e-09 36.1 0.1 1.8 1 1 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPI34744.1 - 0.0013 17.9 15.7 0.0013 17.9 15.7 3.4 2 1 1 3 3 3 3 ABC-2 family transporter protein AAA_18 PF13238.6 KPI34744.1 - 0.0023 18.5 0.1 2.2 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KPI34744.1 - 0.0069 16.1 0.1 3.6 7.4 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain dNK PF01712.19 KPI34744.1 - 0.047 13.5 0.2 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase SMC_N PF02463.19 KPI34744.1 - 0.2 11.1 0.5 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain p450 PF00067.22 KPI34745.1 - 9e-44 150.0 0.0 1.4e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.19 KPI34746.1 - 1.6e-20 73.4 15.9 2e-20 73.2 7.7 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPI34746.1 - 1.1e-19 70.6 0.1 2.1e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KPI34746.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HAT PF02184.16 KPI34746.1 - 0.27 11.2 3.7 10 6.2 0.1 2.6 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Peptidase_M28 PF04389.17 KPI34747.1 - 5.7e-31 107.7 0.0 7.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPI34747.1 - 1.6e-12 47.3 0.4 3.3e-12 46.3 0.4 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KPI34747.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 FAD_binding_3 PF01494.19 KPI34748.1 - 1.2e-49 169.5 0.0 1.5e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI34748.1 - 8.1e-09 35.5 0.3 3.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI34748.1 - 1.2e-05 24.7 0.5 0.00013 21.3 0.5 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI34748.1 - 9.7e-05 22.5 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPI34748.1 - 0.00019 20.3 0.1 0.00044 19.1 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KPI34748.1 - 0.00019 20.8 0.0 0.0016 17.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI34748.1 - 0.0015 18.0 1.0 0.0039 16.6 1.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI34748.1 - 0.0017 17.6 0.1 0.0032 16.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KPI34748.1 - 0.0017 17.5 0.6 0.0031 16.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 KPI34748.1 - 0.0022 17.6 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 KPI34748.1 - 0.0084 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 KPI34748.1 - 0.013 14.5 0.6 0.034 13.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KPI34748.1 - 0.034 14.7 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPI34748.1 - 0.037 14.5 0.0 0.077 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KPI34748.1 - 0.043 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KPI34748.1 - 0.047 12.8 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KPI34748.1 - 0.049 13.5 0.4 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 KPI34748.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KPI34748.1 - 0.099 11.5 0.2 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KPI34748.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KPI34748.1 - 0.19 11.0 0.2 0.28 10.5 0.2 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KPI34748.1 - 0.2 10.9 0.8 46 3.1 0.1 3.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAA_hydrolase PF01557.18 KPI34749.1 - 1.5e-61 207.9 0.0 1.9e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sugar_tr PF00083.24 KPI34750.1 - 8.3e-105 351.2 24.5 1e-104 350.9 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI34750.1 - 6.1e-23 81.3 44.2 3.6e-20 72.2 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.6 KPI34751.1 - 1.4e-08 35.5 0.0 2.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 KPI34753.1 - 1.5e-15 57.3 2.3 5.1e-14 52.3 2.3 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI34753.1 - 4.6e-08 33.0 7.9 0.00011 21.9 2.3 3.0 1 1 2 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI34753.1 - 2.9e-06 26.6 1.7 6.6e-06 25.5 1.3 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI34753.1 - 1.3e-05 25.3 0.3 4.8e-05 23.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34753.1 - 5.6e-05 22.5 0.3 0.0013 18.0 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI34753.1 - 0.0006 18.6 0.4 0.0024 16.7 0.4 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KPI34753.1 - 0.0022 18.5 0.1 0.045 14.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI34753.1 - 0.0048 16.2 1.6 0.0075 15.5 0.4 1.9 2 1 0 2 2 2 1 Thi4 family SE PF08491.10 KPI34753.1 - 0.013 14.5 0.0 0.046 12.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 KPI34753.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KPI34753.1 - 0.023 13.6 0.3 1.1 8.0 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KPI34753.1 - 0.17 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI34753.1 - 0.18 10.9 0.2 0.24 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3328 PF11807.8 KPI34754.1 - 1.7e-36 126.1 2.0 2.3e-36 125.6 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_transf_28 PF03033.20 KPI34755.1 - 4.3e-17 62.4 0.0 1.5e-15 57.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPI34755.1 - 0.0001 21.3 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KPI34755.1 - 0.02 14.7 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KPI34755.1 - 0.19 11.7 0.1 0.49 10.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain AA_permease PF00324.21 KPI34756.1 - 5.1e-91 305.6 40.4 6.5e-91 305.3 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI34756.1 - 2.3e-22 79.4 41.8 2.9e-22 79.1 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.26 KPI34757.1 - 2.3e-07 30.9 0.0 6.1e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI34757.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain TRI12 PF06609.13 KPI34758.1 - 3.7e-23 81.8 12.9 5e-23 81.4 12.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI34758.1 - 0.00015 20.8 45.0 0.0026 16.8 36.7 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPI34759.1 - 3.1e-07 29.6 2.2 4.4e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF3500 PF12006.8 KPI34760.1 - 1.3e-94 317.1 0.0 1.5e-94 316.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.19 KPI34761.1 - 2.2e-51 175.2 0.0 2.5e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI34761.1 - 8.6e-07 28.5 0.1 9e-05 21.8 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI34761.1 - 7.7e-06 25.4 0.2 0.00028 20.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI34761.1 - 0.00017 22.1 0.1 0.006 17.1 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI34761.1 - 0.00028 20.6 0.1 0.16 11.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI34761.1 - 0.00072 18.7 1.2 0.12 11.5 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI34761.1 - 0.0021 18.3 0.0 0.008 16.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI34761.1 - 0.018 14.4 0.3 0.11 11.8 0.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI34761.1 - 0.028 13.1 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KPI34761.1 - 0.043 13.2 0.0 0.16 11.3 0.0 1.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KPI34761.1 - 0.094 12.3 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 KPI34761.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KPI34761.1 - 0.15 11.3 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family PALP PF00291.25 KPI34762.1 - 1.9e-42 145.7 0.0 2.2e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 KPI34763.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI34763.1 - 5.1e-25 88.2 0.0 6.3e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI34763.1 - 2.6e-06 27.6 0.0 1.2e-05 25.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Flavi_propep PF01570.17 KPI34763.1 - 0.016 15.2 0.8 0.042 13.8 0.8 1.7 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide RIO1 PF01163.22 KPI34763.1 - 0.034 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KPI34763.1 - 0.04 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KPI34763.1 - 0.042 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KPI34763.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1929 PF09118.11 KPI34764.1 - 4.9e-21 74.8 0.1 1.8e-20 73.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_1 PF01344.25 KPI34764.1 - 2.2e-11 43.1 5.4 7e-08 31.9 0.4 3.6 4 0 0 4 4 4 2 Kelch motif PAN_1 PF00024.26 KPI34764.1 - 2.6e-10 40.1 8.3 0.0001 22.2 0.9 2.5 2 0 0 2 2 2 2 PAN domain Kelch_6 PF13964.6 KPI34764.1 - 6.2e-10 39.0 7.6 0.0036 17.5 0.2 4.8 3 1 1 4 4 4 3 Kelch motif PAN_4 PF14295.6 KPI34764.1 - 2.8e-06 27.1 3.9 0.0097 15.8 0.5 2.6 2 0 0 2 2 2 2 PAN domain Kelch_4 PF13418.6 KPI34764.1 - 5.7e-05 23.0 3.3 2 8.5 0.3 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain PAN_3 PF08277.12 KPI34764.1 - 0.00016 21.4 2.0 0.099 12.5 0.1 2.6 2 0 0 2 2 2 2 PAN-like domain Kelch_2 PF07646.15 KPI34764.1 - 0.017 15.1 2.8 0.19 11.8 0.2 3.6 4 0 0 4 4 4 0 Kelch motif PAN_2 PF08276.11 KPI34764.1 - 0.039 14.1 10.3 0.034 14.3 2.2 2.6 2 0 0 2 2 2 0 PAN-like domain MANEC PF07502.14 KPI34764.1 - 0.042 14.1 6.1 0.32 11.3 0.9 2.5 2 0 0 2 2 2 0 MANEC domain Peptidase_S28 PF05577.12 KPI34765.1 - 3.3e-38 131.6 4.0 2e-36 125.7 4.0 2.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Pkinase PF00069.25 KPI34767.1 - 1.4e-35 123.0 0.0 2.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI34767.1 - 2.9e-20 72.6 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI34767.1 - 0.0011 17.8 0.1 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KPI34767.1 - 0.012 15.5 0.5 0.04 13.8 0.4 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KPI34767.1 - 0.071 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KPI34767.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF3328 PF11807.8 KPI34768.1 - 1.4e-34 119.8 0.3 1.6e-34 119.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NDUF_B7 PF05676.13 KPI34768.1 - 0.15 11.8 1.0 1 9.1 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) p450 PF00067.22 KPI34769.1 - 1.1e-64 218.9 0.0 1.5e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KPI34771.1 - 3.2e-27 95.7 1.5 3.7e-27 95.5 0.5 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Duffy_binding PF05424.11 KPI34772.1 - 0.091 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Duffy binding domain DUF1098 PF06497.11 KPI34774.1 - 0.005 17.3 0.9 0.012 16.0 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1098) Ribosomal_S5 PF00333.20 KPI34775.1 - 0.17 11.9 0.2 9.8 6.2 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain PAS_9 PF13426.7 KPI34776.1 - 1.7e-25 89.3 0.0 3.1e-17 62.7 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KPI34776.1 - 4.9e-19 68.4 0.0 5.5e-11 42.6 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 KPI34776.1 - 1.8e-14 53.0 7.3 3.7e-14 52.0 7.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KPI34776.1 - 1.2e-13 51.0 0.0 0.00029 20.8 0.0 4.0 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 KPI34776.1 - 1.8e-10 40.9 0.0 4.5e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KPI34776.1 - 3.8e-10 40.0 0.0 0.0011 19.2 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 KPI34776.1 - 0.00016 22.3 0.0 0.0038 17.9 0.1 2.8 3 0 0 3 3 3 1 PAS fold Coatomer_WDAD PF04053.14 KPI34777.1 - 1.1e-140 469.7 0.0 1.7e-140 469.0 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KPI34777.1 - 2.5e-102 342.7 0.0 3.4e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KPI34777.1 - 3.7e-36 122.5 14.4 1.5e-07 32.0 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI34777.1 - 3.4e-07 30.5 0.2 0.038 14.3 0.0 5.2 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI34777.1 - 0.0037 16.0 7.2 1.6 7.3 0.1 3.9 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Peptidase_C12 PF01088.21 KPI34778.1 - 2e-29 102.9 0.0 8.1e-29 100.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 KxDL PF10241.9 KPI34780.1 - 1.2e-25 89.5 0.4 1.9e-25 89.0 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein Arg_decarbox_C PF17944.1 KPI34780.1 - 0.31 11.6 2.7 0.61 10.7 0.6 2.4 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension Sec23_trunk PF04811.15 KPI34781.1 - 1.7e-76 257.0 0.0 2.4e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KPI34781.1 - 9.9e-30 103.1 0.0 2.9e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KPI34781.1 - 9.6e-24 83.2 0.0 1.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KPI34781.1 - 9.3e-15 54.4 2.7 1.7e-14 53.6 2.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KPI34781.1 - 1.9e-10 40.5 0.0 4.8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KPI34781.1 - 0.13 11.7 0.3 0.42 10.0 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ABC2_membrane PF01061.24 KPI34782.1 - 5.9e-75 251.3 55.5 2e-41 141.8 23.2 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KPI34782.1 - 7.4e-38 130.2 0.6 5.3e-18 65.9 0.0 3.6 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 KPI34782.1 - 2e-31 107.7 0.1 2e-31 107.7 0.1 3.9 5 0 0 5 5 2 1 CDR ABC transporter ABC_trans_N PF14510.6 KPI34782.1 - 2.1e-14 53.9 0.2 2.1e-14 53.9 0.2 3.1 3 0 0 3 3 3 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPI34782.1 - 5.8e-08 32.2 10.6 5.8e-08 32.2 10.6 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KPI34782.1 - 9.7e-07 28.8 0.3 7.5e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KPI34782.1 - 1.4e-06 28.0 0.5 3.5e-05 23.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI34782.1 - 8.6e-06 26.2 0.2 0.0022 18.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KPI34782.1 - 1.7e-05 24.8 0.1 0.13 12.0 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KPI34782.1 - 4e-05 23.8 0.0 0.0087 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPI34782.1 - 5.8e-05 22.7 0.8 0.0073 16.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KPI34782.1 - 0.00013 21.4 0.0 0.22 10.9 0.0 4.1 4 1 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KPI34782.1 - 0.00019 22.0 0.0 0.017 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI34782.1 - 0.0018 18.6 0.1 0.34 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KPI34782.1 - 0.0033 17.8 1.4 0.16 12.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KPI34782.1 - 0.0059 16.3 0.4 0.43 10.3 0.1 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KPI34782.1 - 0.012 15.5 0.6 0.77 9.7 0.1 2.8 3 0 0 3 3 2 0 NACHT domain cobW PF02492.19 KPI34782.1 - 0.015 14.9 0.2 0.88 9.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KPI34782.1 - 0.016 15.7 0.2 0.12 12.9 0.0 2.5 4 0 0 4 4 2 0 AAA domain dNK PF01712.19 KPI34782.1 - 0.04 13.8 0.0 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 KPI34782.1 - 0.071 13.5 0.0 20 5.6 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KPI34782.1 - 0.11 12.9 0.2 6.2 7.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 KPI34782.1 - 0.11 12.5 0.0 19 5.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KPI34782.1 - 0.17 11.6 1.6 7.8 6.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 KPI34782.1 - 0.41 10.5 1.7 4.2 7.2 0.0 2.7 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 MFS_1 PF07690.16 KPI34785.1 - 6e-21 74.7 24.0 6.2e-17 61.5 15.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF5389 PF17364.2 KPI34785.1 - 0.012 15.7 1.6 0.052 13.6 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5389) Wzz PF02706.15 KPI34785.1 - 0.067 13.5 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 Chain length determinant protein MAP17 PF15807.5 KPI34785.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 eIF2A PF08662.11 KPI34786.1 - 1.6e-82 276.1 0.0 1.6e-80 269.6 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A SH3-RhoG_link PF16609.5 KPI34786.1 - 0.0056 16.4 2.6 0.012 15.3 2.6 1.5 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region WD40 PF00400.32 KPI34786.1 - 0.11 13.4 1.3 10 7.2 0.1 4.3 4 1 0 5 5 5 0 WD domain, G-beta repeat FlaG PF03646.15 KPI34786.1 - 1.8 8.8 0.0 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 FlaG protein HUN PF08729.10 KPI34787.1 - 5.6e-08 32.7 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain EMP70 PF02990.16 KPI34788.1 - 1.9e-199 663.6 0.4 1.9e-199 663.6 0.4 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 SUR7 PF06687.12 KPI34788.1 - 9.3 5.8 12.8 0.92 9.1 4.6 2.9 3 0 0 3 3 3 0 SUR7/PalI family Abhydrolase_6 PF12697.7 KPI34790.1 - 3.4e-10 40.9 0.1 4.9e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.29 KPI34791.1 - 9.1e-49 165.3 0.0 3.7e-38 130.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI34791.1 - 1.5e-12 47.1 0.1 1e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain CDC48_2 PF02933.17 KPI34791.1 - 2.5e-08 33.5 0.2 8.8e-07 28.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KPI34791.1 - 1e-06 29.1 0.2 0.00016 22.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPI34791.1 - 1.4e-05 25.7 0.0 0.09 13.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KPI34791.1 - 2.2e-05 24.9 0.0 0.01 16.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KPI34791.1 - 3.7e-05 23.9 0.0 8.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KPI34791.1 - 9.9e-05 21.8 0.1 0.0052 16.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KPI34791.1 - 0.0001 21.7 0.1 0.043 13.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KPI34791.1 - 0.00011 22.4 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KPI34791.1 - 0.00014 21.9 0.1 0.0031 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KPI34791.1 - 0.00014 22.2 0.0 0.61 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 KPI34791.1 - 0.00019 21.6 0.0 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 KPI34791.1 - 0.0002 21.2 0.1 0.082 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KPI34791.1 - 0.00035 20.3 0.2 0.14 11.9 0.1 2.9 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KPI34791.1 - 0.00056 20.3 0.0 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KPI34791.1 - 0.0043 17.6 0.1 0.034 14.7 0.1 2.4 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 KPI34791.1 - 0.0064 15.9 0.7 0.051 12.9 0.1 2.4 2 1 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 KPI34791.1 - 0.0074 16.0 0.0 0.095 12.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KPI34791.1 - 0.0085 16.1 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KPI34791.1 - 0.0092 15.5 0.2 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 KPI34791.1 - 0.0093 16.0 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KPI34791.1 - 0.01 15.4 0.5 5.4 6.5 0.0 2.9 3 1 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KPI34791.1 - 0.018 14.2 0.2 2.7 7.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KPI34791.1 - 0.019 14.9 2.9 7.2 6.5 0.0 3.6 4 0 0 4 4 3 0 NACHT domain TniB PF05621.11 KPI34791.1 - 0.032 13.6 0.6 3.9 6.8 0.1 3.4 3 1 0 3 3 3 0 Bacterial TniB protein KTI12 PF08433.10 KPI34791.1 - 0.054 12.9 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 KPI34791.1 - 0.084 13.2 0.2 0.4 11.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 KPI34791.1 - 0.099 12.1 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KPI34791.1 - 0.12 12.0 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 KPI34791.1 - 0.12 11.4 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Hydin_ADK PF17213.3 KPI34791.1 - 0.16 12.2 0.1 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain HET PF06985.11 KPI34792.1 - 5e-16 59.4 0.7 8.8e-12 45.6 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RPN6_N PF18055.1 KPI34793.1 - 9.2e-45 151.8 0.1 9.2e-45 151.8 0.1 2.6 3 1 1 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KPI34793.1 - 2.2e-20 73.1 0.8 6.7e-20 71.6 0.1 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KPI34793.1 - 9.2e-11 41.3 0.1 2.9e-10 39.7 0.1 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KPI34793.1 - 0.001 18.9 3.3 3.7 7.8 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPI34793.1 - 0.0014 18.1 6.6 0.0028 17.1 3.7 2.6 1 1 2 3 3 3 1 MalT-like TPR region TPR_12 PF13424.6 KPI34793.1 - 0.0014 18.8 13.1 1 9.7 1.8 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat DDRGK PF09756.9 KPI34793.1 - 0.0019 17.8 0.1 0.0042 16.7 0.1 1.6 1 0 0 1 1 1 1 DDRGK domain Peptidase_M16_C PF05193.21 KPI34793.1 - 0.019 15.0 0.1 0.047 13.7 0.1 1.7 1 0 0 1 1 1 0 Peptidase M16 inactive domain CNP_C_terminal PF17839.1 KPI34793.1 - 0.025 15.3 0.2 0.89 10.3 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase TPR_1 PF00515.28 KPI34793.1 - 0.12 12.2 3.9 40 4.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4398 PF14346.6 KPI34793.1 - 0.57 10.8 0.1 0.57 10.8 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4398) Paramecium_SA PF01508.16 KPI34795.1 - 1.6 9.2 4.6 5.3 7.5 4.6 2.0 1 1 0 1 1 1 0 Paramecium surface antigen domain Voltage_CLC PF00654.20 KPI34797.1 - 1e-77 261.8 15.1 1e-77 261.8 15.1 2.6 3 1 0 3 3 3 1 Voltage gated chloride channel RPAP1_C PF08620.10 KPI34798.1 - 2.5e-25 88.3 0.0 5e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KPI34798.1 - 1.3e-15 56.8 3.0 2.4e-15 56.0 3.0 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF3921 PF13060.6 KPI34798.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Amidohydro_2 PF04909.14 KPI34799.1 - 5.3e-46 157.7 0.1 6.4e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Acetyltransf_13 PF13880.6 KPI34800.1 - 5.2e-28 96.8 0.0 1.2e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KPI34800.1 - 5.6e-10 38.9 0.2 1.2e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KPI34800.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sof1 PF04158.14 KPI34801.1 - 6.1e-33 113.0 12.9 1.1e-32 112.1 12.9 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KPI34801.1 - 3.5e-28 97.2 7.2 2e-05 25.2 0.4 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI34801.1 - 1e-09 38.6 0.3 0.023 15.0 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI34801.1 - 1.2e-05 24.5 0.0 0.027 13.4 0.0 2.5 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KPI34801.1 - 0.055 12.0 0.1 0.33 9.4 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain MmgE_PrpD PF03972.14 KPI34802.1 - 1.7e-110 369.6 0.0 2e-110 369.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF3405 PF11885.8 KPI34803.1 - 1.3e-170 568.5 6.9 1.5e-170 568.2 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) HATPase_c PF02518.26 KPI34804.1 - 5.4e-22 78.4 0.1 1.6e-21 76.9 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI34804.1 - 2.8e-16 59.7 0.0 1.9e-09 37.7 0.0 3.4 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KPI34804.1 - 1.1e-15 57.4 0.0 2.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KPI34804.1 - 3e-10 40.3 0.4 0.00058 20.1 0.1 3.7 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KPI34804.1 - 0.00065 19.9 0.0 0.061 13.6 0.0 3.2 3 0 0 3 3 3 1 PAS fold Peptidase_M13_N PF05649.13 KPI34805.1 - 5.2e-57 194.3 0.0 9.7e-57 193.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M13 Chlorosome_CsmC PF11098.8 KPI34805.1 - 0.032 14.2 2.5 0.067 13.2 2.5 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF932 PF06067.11 KPI34805.1 - 0.15 11.8 1.9 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF932) DUF883 PF05957.13 KPI34805.1 - 2.9 8.6 10.9 0.12 12.9 3.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HET PF06985.11 KPI34806.1 - 5.4e-06 26.8 0.1 9.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AurF PF11583.8 KPI34806.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF EF-hand_1 PF00036.32 KPI34807.1 - 3.9e-25 85.5 5.5 3e-08 32.7 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KPI34807.1 - 2.4e-24 85.6 3.5 7.9e-15 55.1 0.2 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KPI34807.1 - 8.2e-22 75.2 2.0 1.6e-05 24.5 0.2 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KPI34807.1 - 5.8e-17 60.3 4.7 9.7e-06 24.9 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KPI34807.1 - 8.9e-14 51.1 6.0 5.2e-06 26.2 0.3 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KPI34807.1 - 3.2e-08 33.4 4.2 0.0097 15.8 0.1 3.7 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KPI34807.1 - 8.6e-05 22.8 0.7 0.24 11.7 0.2 3.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KPI34807.1 - 0.0016 18.7 0.2 0.014 15.7 0.0 2.5 2 2 1 3 3 3 1 EF-hand domain EF-hand_14 PF17959.1 KPI34807.1 - 0.037 14.4 1.6 6.6 7.1 0.0 3.3 3 1 0 3 3 3 0 EF-hand domain EF-hand_2 PF09068.11 KPI34807.1 - 0.041 14.0 0.0 1.9 8.6 0.0 2.9 3 0 0 3 3 3 0 EF hand SRP68 PF16969.5 KPI34808.1 - 9.7e-141 470.5 7.9 1.1e-140 470.3 7.9 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 KPI34808.1 - 0.00032 19.6 0.1 0.00062 18.7 0.1 1.4 1 0 0 1 1 1 1 BRO1-like domain Jag_N PF14804.6 KPI34808.1 - 0.1 13.0 0.4 7.1 7.1 0.2 3.1 3 0 0 3 3 3 0 Jag N-terminus Hormone_1 PF00103.20 KPI34808.1 - 0.13 11.9 0.4 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 Somatotropin hormone family CAP_N PF01213.19 KPI34809.1 - 0.051 13.0 0.0 0.06 12.8 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAM176 PF14851.6 KPI34809.1 - 0.24 11.0 2.9 0.083 12.5 0.7 1.4 2 0 0 2 2 2 0 FAM176 family Radial_spoke PF04712.12 KPI34809.1 - 0.25 10.2 0.8 0.27 10.2 0.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein BUD22 PF09073.10 KPI34809.1 - 0.37 10.1 7.2 0.4 10.0 7.2 1.0 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KPI34809.1 - 0.59 9.4 7.0 0.88 8.8 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KPI34809.1 - 1.7 9.1 18.9 0.063 13.7 12.6 1.8 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 KPI34809.1 - 3.2 8.0 13.8 0.69 10.2 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KPI34809.1 - 3.4 5.6 11.7 4 5.4 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Spo7 PF03907.13 KPI34810.1 - 3e-76 255.8 2.7 5.5e-76 254.9 2.7 1.4 1 0 0 1 1 1 1 Spo7-like protein Macoilin PF09726.9 KPI34810.1 - 1 7.8 9.4 1.3 7.5 9.4 1.1 1 0 0 1 1 1 0 Macoilin family NTP_transferase PF00483.23 KPI34811.1 - 1.2e-49 169.1 0.0 2.8e-49 167.9 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KPI34811.1 - 1.3e-14 53.2 6.6 5.4e-11 41.8 1.0 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KPI34811.1 - 2.2e-10 41.1 0.0 4.5e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KPI34811.1 - 2.2e-05 24.1 1.7 2.2e-05 24.1 1.7 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 KPI34811.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 KPI34811.1 - 0.11 10.6 0.3 0.69 8.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) RabGAP-TBC PF00566.18 KPI34812.1 - 2.4e-31 109.1 0.0 3.1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GMC_oxred_N PF00732.19 KPI34814.1 - 2.8e-52 178.0 0.0 3.6e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI34814.1 - 1.7e-25 90.2 0.0 3.9e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI34814.1 - 2.7e-09 36.6 0.0 8.8e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI34814.1 - 1.6e-06 28.2 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI34814.1 - 0.00029 20.2 0.1 0.038 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI34814.1 - 0.00037 20.2 1.0 0.0022 17.6 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI34814.1 - 0.0027 17.0 0.1 0.091 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI34814.1 - 0.0073 15.0 0.0 0.068 11.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KPI34814.1 - 0.015 14.5 0.1 0.035 13.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KPI34814.1 - 0.067 13.8 0.9 0.37 11.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI34814.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPI34814.1 - 0.13 11.4 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Ge1_WD40 PF16529.5 KPI34815.1 - 0.00017 20.7 0.5 0.024 13.6 0.0 2.5 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2415 PF10313.9 KPI34815.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Rad9_Rad53_bind PF08605.10 KPI34815.1 - 0.036 14.3 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding WD40 PF00400.32 KPI34815.1 - 0.053 14.4 3.1 17 6.5 0.2 4.5 4 1 0 4 4 4 0 WD domain, G-beta repeat Lactamase_B PF00753.27 KPI34816.1 - 0.0017 18.4 0.1 0.0033 17.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SAM_2 PF07647.17 KPI34817.1 - 4.5e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPI34817.1 - 0.0031 17.9 0.1 0.0067 16.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Alpha_adaptinC2 PF02883.20 KPI34817.1 - 0.067 13.5 2.2 1 9.7 0.3 2.8 2 0 0 2 2 2 0 Adaptin C-terminal domain T2SSM PF04612.12 KPI34818.1 - 1.8 8.6 4.5 2.9 7.9 4.5 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TFIIF_alpha PF05793.12 KPI34819.1 - 8.1e-09 34.6 39.7 8.1e-09 34.6 39.7 2.0 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L30_N PF08079.12 KPI34819.1 - 0.022 15.0 9.2 0.022 15.0 9.2 4.5 5 0 0 5 5 5 0 Ribosomal L30 N-terminal domain DUF4410 PF14366.6 KPI34819.1 - 0.59 10.0 2.8 16 5.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) TPP_enzyme_N PF02776.18 KPI34820.1 - 7.7e-34 116.8 0.0 1.1e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPI34820.1 - 4.3e-14 52.6 0.4 3.3e-13 49.7 0.1 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI34820.1 - 3.4e-13 49.5 0.0 7.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.25 KPI34821.1 - 1.1e-28 100.0 0.5 1.5e-28 99.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34821.1 - 4.5e-24 85.3 0.2 6e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34821.1 - 2.9e-06 27.3 0.2 1.3e-05 25.2 0.0 2.0 3 0 0 3 3 3 1 KR domain Epimerase PF01370.21 KPI34821.1 - 1.9e-05 24.3 0.0 0.039 13.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KPI34821.1 - 0.02 14.2 0.0 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KPI34821.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PetM PF08041.11 KPI34822.1 - 1.6 8.4 7.2 5.5 6.7 1.2 2.7 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Phage_holin_5_2 PF16079.5 KPI34822.1 - 2 8.8 6.8 2.6 8.4 0.7 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF2564 PF10819.8 KPI34823.1 - 7.4 7.0 7.0 0.62 10.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Ribosomal_S8e PF01201.22 KPI34824.1 - 1.6e-44 151.4 0.8 3.1e-44 150.5 0.7 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e SPATA3 PF15662.5 KPI34824.1 - 2.1 8.9 7.2 3.3 8.3 7.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF2390 PF09523.10 KPI34824.1 - 4 7.8 6.6 8.2 6.8 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Pannexin_like PF12534.8 KPI34824.1 - 8.4 5.4 5.8 12 4.9 5.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 MatE PF01554.18 KPI34825.1 - 2.6e-47 160.5 19.3 5.3e-32 110.7 4.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KPI34825.1 - 5.3e-09 36.3 6.8 5.3e-09 36.3 6.8 3.2 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain Cyclin_N PF00134.23 KPI34826.1 - 3.2e-07 30.1 0.0 7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KPI34826.1 - 3.3e-05 24.3 0.8 7.6e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin Abhydrolase_1 PF00561.20 KPI34828.1 - 1.3e-22 80.7 0.0 4e-22 79.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI34828.1 - 3.4e-18 67.0 0.0 1.5e-16 61.7 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI34828.1 - 7.3e-18 64.7 0.0 6.4e-17 61.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KPI34828.1 - 3.7e-07 30.1 0.0 7.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KPI34828.1 - 9.9e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 KPI34828.1 - 0.00069 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 KPI34828.1 - 0.0017 17.4 0.1 0.0044 16.0 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KPI34828.1 - 0.0026 17.6 0.0 2.1 8.1 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KPI34828.1 - 0.0058 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2920 PF11144.8 KPI34828.1 - 0.016 14.4 0.0 0.41 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KPI34828.1 - 0.032 14.1 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KPI34828.1 - 0.04 12.9 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.13 KPI34828.1 - 0.042 13.7 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S15 PF02129.18 KPI34828.1 - 0.046 13.3 1.1 0.49 9.9 0.2 2.7 3 1 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 KPI34828.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KPI34828.1 - 0.15 12.1 0.4 0.96 9.5 0.3 2.2 1 1 0 1 1 1 0 Thioesterase domain ATG16 PF08614.11 KPI34829.1 - 0.00019 21.7 15.5 0.00019 21.7 15.5 4.9 1 1 2 3 3 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KPI34829.1 - 0.00062 18.7 12.2 0.00062 18.7 12.2 3.1 1 1 2 3 3 3 1 Spc7 kinetochore protein DUF4686 PF15742.5 KPI34829.1 - 0.00091 18.5 13.5 0.00091 18.5 13.5 3.7 1 1 1 3 3 3 1 Domain of unknown function (DUF4686) DUF4200 PF13863.6 KPI34829.1 - 0.001 19.4 11.3 0.0018 18.6 8.5 4.6 1 1 3 4 4 4 3 Domain of unknown function (DUF4200) Spc42p PF11544.8 KPI34829.1 - 0.0013 18.6 0.2 0.0013 18.6 0.2 4.1 3 1 1 4 4 4 1 Spindle pole body component Spc42p KASH_CCD PF14662.6 KPI34829.1 - 0.0036 17.2 2.7 0.0036 17.2 2.7 4.3 1 1 3 4 4 4 1 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 KPI34829.1 - 0.01 15.2 9.6 0.01 15.2 9.6 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KPI34829.1 - 0.011 15.8 42.0 0.068 13.3 17.2 3.8 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 KPI34829.1 - 0.046 13.8 27.8 0.094 12.8 5.1 5.9 2 2 3 5 5 5 0 TolA binding protein trimerisation Filament PF00038.21 KPI34829.1 - 0.082 12.5 42.7 1.4 8.4 21.4 3.7 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.6 KPI34829.1 - 0.1 11.2 34.6 0.017 13.8 14.7 2.3 1 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 KPI34829.1 - 0.19 11.8 22.1 0.16 12.0 0.6 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KPI34829.1 - 1.1 9.7 23.8 0.073 13.5 5.8 4.5 3 2 0 3 3 3 0 Snapin/Pallidin YabA PF06156.13 KPI34829.1 - 1.4 9.6 26.0 1.9 9.2 4.4 4.8 2 2 3 5 5 5 0 Initiation control protein YabA PG_binding_3 PF09374.10 KPI34829.1 - 2 8.7 4.5 15 5.9 0.2 2.9 3 0 0 3 3 2 0 Predicted Peptidoglycan domain TMF_DNA_bd PF12329.8 KPI34829.1 - 2.5 8.2 47.3 9.1 6.4 18.1 6.5 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KPI34829.1 - 2.6 8.7 31.9 7.1 7.3 3.8 6.7 2 2 5 7 7 7 0 SlyX APG6_N PF17675.1 KPI34829.1 - 3.7 8.1 54.9 2.5 8.6 19.2 4.6 1 1 3 4 4 4 0 Apg6 coiled-coil region Bacillus_HBL PF05791.11 KPI34829.1 - 5.8 6.7 19.4 0.32 10.8 4.8 3.6 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) SRP40_C PF05022.12 KPI34830.1 - 6.1e-18 65.5 3.9 1.1e-17 64.6 3.9 1.5 1 0 0 1 1 1 1 SRP40, C-terminal domain WW PF00397.26 KPI34832.1 - 4.9e-08 32.9 8.9 1.1e-07 31.8 8.9 1.7 1 0 0 1 1 1 1 WW domain Gly-zipper_Omp PF13488.6 KPI34832.1 - 0.00061 19.7 2.8 0.0012 18.7 2.8 1.5 1 0 0 1 1 1 1 Glycine zipper DUF1090 PF06476.12 KPI34832.1 - 0.0099 16.0 0.1 0.0099 16.0 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1090) Apolipoprotein PF01442.18 KPI34832.1 - 0.012 15.6 1.7 0.018 14.9 1.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain RRF PF01765.19 KPI34832.1 - 0.21 11.5 0.3 0.45 10.4 0.0 1.6 2 0 0 2 2 2 0 Ribosome recycling factor SMN PF06003.12 KPI34832.1 - 0.28 10.4 17.4 0.07 12.4 6.8 2.4 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) ANAPC3 PF12895.7 KPI34833.1 - 5.6e-11 42.5 4.1 0.00014 22.0 0.2 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KPI34833.1 - 5.6e-10 39.6 7.7 0.0016 18.9 0.6 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI34833.1 - 8.7e-10 38.0 18.2 0.49 10.6 0.0 9.3 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPI34833.1 - 1.1e-08 35.2 13.1 0.37 11.7 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPI34833.1 - 3.8e-07 30.0 1.0 0.0081 16.5 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI34833.1 - 0.00032 21.3 24.5 0.067 13.9 0.5 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPI34833.1 - 0.00056 20.2 12.7 0.65 10.3 0.0 6.5 6 2 1 7 7 7 3 Tetratricopeptide repeat NARP1 PF12569.8 KPI34833.1 - 0.0011 18.0 0.1 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KPI34833.1 - 0.0014 18.3 11.3 5.8 6.9 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPI34833.1 - 0.0039 17.7 0.2 7.1 7.5 0.0 5.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KPI34833.1 - 0.0071 16.6 0.5 0.37 11.2 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPI34833.1 - 0.0096 15.6 6.0 26 4.6 0.1 5.8 5 1 1 6 6 6 0 TPR repeat HrpB1_HrpK PF09613.10 KPI34833.1 - 0.1 12.3 1.1 16 5.1 0.0 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 KPI34833.1 - 0.29 11.3 5.3 0.59 10.3 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec3_C PF09763.9 KPI34834.1 - 8.8e-178 592.9 9.9 1.2e-177 592.5 9.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KPI34834.1 - 3.8e-28 97.4 0.1 9.1e-28 96.2 0.1 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KPI34834.1 - 0.013 14.3 2.4 0.021 13.6 0.6 2.0 2 0 0 2 2 2 0 Vps52 / Sac2 family Sec3_C_2 PF15278.6 KPI34834.1 - 0.1 12.9 0.1 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 Sec3 exocyst complex subunit DUF4050 PF13259.6 KPI34835.1 - 5e-43 147.6 1.7 5e-43 147.6 1.7 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF4050) His_Phos_2 PF00328.22 KPI34836.1 - 2.9e-35 122.4 0.0 4.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sororin PF09666.10 KPI34837.1 - 0.027 14.7 0.1 0.036 14.3 0.1 1.3 1 0 0 1 1 1 0 Sororin protein REPA_OB_2 PF16900.5 KPI34837.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 Replication protein A OB domain GWT1 PF06423.12 KPI34839.1 - 0.23 11.6 5.5 0.15 12.1 1.9 2.2 1 1 1 2 2 2 0 GWT1 SLATT_1 PF18181.1 KPI34839.1 - 5.9 6.8 6.6 0.99 9.4 1.9 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Rab5ip PF07019.12 KPI34841.1 - 2.5e-21 76.0 3.8 4.8e-21 75.1 3.8 1.5 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SPDY PF03771.16 KPI34841.1 - 0.086 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Suc_Fer-like PF06999.12 KPI34842.1 - 2.6e-67 226.5 0.0 3.2e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4609 PF15382.6 KPI34842.1 - 0.1 12.5 2.3 0.11 12.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Sulfatase_C PF14707.6 KPI34843.1 - 0.11 13.3 0.0 1.7 9.4 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase EPO_TPO PF00758.18 KPI34844.1 - 0.23 11.5 1.0 0.74 9.8 0.1 2.0 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin HMGL-like PF00682.19 KPI34845.1 - 4.4e-77 259.2 1.0 6.2e-77 258.7 1.0 1.2 1 0 0 1 1 1 1 HMGL-like HSP70 PF00012.20 KPI34846.1 - 1.1e-267 889.2 16.7 1.2e-267 889.0 16.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPI34846.1 - 4.9e-15 55.2 6.8 3.4e-13 49.1 2.7 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KPI34846.1 - 0.00069 19.4 0.0 0.0022 17.7 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Med9 PF07544.13 KPI34846.1 - 0.011 15.8 6.0 0.15 12.2 0.9 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TetR_C_25 PF17933.1 KPI34846.1 - 0.043 14.1 0.1 7.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FtsA PF14450.6 KPI34846.1 - 1.3 9.4 11.5 0.87 10.0 0.3 3.8 3 3 0 3 3 3 0 Cell division protein FtsA DSHCT PF08148.12 KPI34847.1 - 3.2e-51 173.3 0.8 7.7e-51 172.0 0.4 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KPI34847.1 - 9.5e-42 142.0 0.0 2.2e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KPI34847.1 - 1.9e-22 80.5 0.7 3.1e-22 79.8 0.7 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KPI34847.1 - 2.3e-19 69.8 0.0 7.8e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI34847.1 - 2.3e-06 27.7 0.5 1.3e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI34847.1 - 4.5e-06 27.0 0.0 2e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 KPI34848.1 - 9.9e-15 54.7 5.5 1.3e-06 29.0 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI34848.1 - 0.0097 16.2 0.3 1.2 9.5 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CHCH PF06747.13 KPI34849.1 - 8e-07 29.0 3.2 1.4e-06 28.2 3.2 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KPI34849.1 - 0.021 15.2 2.1 0.042 14.3 2.1 1.5 1 0 0 1 1 1 0 GCK domain Sec10 PF07393.11 KPI34849.1 - 0.47 8.8 2.4 0.23 9.8 0.4 1.4 2 0 0 2 2 2 0 Exocyst complex component Sec10 Pyridoxal_deC PF00282.19 KPI34850.1 - 2.3e-13 49.6 0.0 3.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KPI34850.1 - 8.2e-07 28.3 0.0 3.4e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPI34850.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TctB PF07331.11 KPI34851.1 - 0.98 9.7 8.4 0.83 9.9 5.4 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4231 PF14015.6 KPI34851.1 - 2.3 8.7 5.2 10 6.7 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) ATG16 PF08614.11 KPI34852.1 - 0.00029 21.1 25.1 0.00029 21.1 25.1 5.1 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 KPI34852.1 - 0.006 16.2 13.7 0.006 16.2 13.7 4.2 1 1 3 4 4 4 2 HAUS augmin-like complex subunit 3 PI3K_P85_iSH2 PF16454.5 KPI34852.1 - 0.0078 15.8 3.6 0.0078 15.8 3.6 5.2 1 1 3 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3450 PF11932.8 KPI34852.1 - 0.049 12.9 71.3 0.45 9.8 12.6 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 KPI34852.1 - 2.5 8.5 77.1 1.2 9.5 31.2 3.8 1 1 2 3 3 3 0 Fez1 Spc7 PF08317.11 KPI34852.1 - 2.7 6.8 81.4 0.14 11.0 9.6 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KPI34852.1 - 4.5 7.3 76.7 0.023 14.7 11.3 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KPI34852.1 - 8.8 7.0 56.9 9.3 7.0 0.8 6.4 1 1 5 6 6 6 0 Initiation control protein YabA PI_PP_I PF18363.1 KPI34852.1 - 9.1 6.5 16.1 2.4 8.4 0.9 4.4 2 1 3 5 5 5 0 Phosphoinositide phosphatase insertion domain ZapB PF06005.12 KPI34852.1 - 9.4 6.8 83.5 0.18 12.3 13.5 7.2 2 2 5 7 7 7 0 Cell division protein ZapB PAP_assoc PF03828.19 KPI34854.1 - 4.6e-18 65.2 0.0 1.3e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KPI34854.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Aminotran_1_2 PF00155.21 KPI34855.1 - 2.6e-39 135.4 0.0 3.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI34855.1 - 1.4e-13 50.6 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KPI34855.1 - 9.3e-09 34.3 0.0 1.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KPI34855.1 - 6.9e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KPI34855.1 - 0.00056 19.3 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 KPI34855.1 - 0.0016 17.4 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Allinase Met_gamma_lyase PF06838.11 KPI34855.1 - 0.21 10.1 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase CoA_transf_3 PF02515.17 KPI34857.1 - 1.1e-116 390.0 0.0 1.3e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.25 KPI34858.1 - 1.5e-28 99.6 0.0 2.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34858.1 - 1.9e-15 57.1 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34858.1 - 1.4e-11 44.6 0.2 1.6e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KPI34858.1 - 1.2e-08 34.5 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI34858.1 - 0.00047 19.7 0.0 0.028 13.9 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI34858.1 - 0.003 17.0 0.0 0.0076 15.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KPI34858.1 - 0.022 15.0 0.1 0.04 14.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KPI34858.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aspzincin_M35 PF14521.6 KPI34859.1 - 0.0069 16.9 1.2 0.1 13.1 1.2 2.3 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase GMC_oxred_N PF00732.19 KPI34861.1 - 2.1e-63 214.5 0.0 3e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI34861.1 - 6.3e-37 127.3 0.0 1.2e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI34861.1 - 3.7e-07 29.6 0.0 6.9e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KPI34861.1 - 0.074 12.3 0.1 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NCD3G PF07562.14 KPI34861.1 - 0.079 12.9 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR NAD_binding_8 PF13450.6 KPI34861.1 - 0.13 12.5 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lipase_GDSL_2 PF13472.6 KPI34862.1 - 5.3e-05 23.7 1.8 0.0077 16.6 1.8 3.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPI34862.1 - 0.00059 19.9 0.0 0.058 13.4 0.0 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Esterase PF00756.20 KPI34863.1 - 0.0015 18.2 0.0 0.0073 16.0 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KPI34863.1 - 0.011 15.3 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Urocanase_N PF17391.2 KPI34863.1 - 0.092 12.4 0.2 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Urocanase N-terminal domain Tannase PF07519.11 KPI34863.1 - 0.15 11.0 3.2 0.093 11.6 1.3 1.6 2 0 0 2 2 2 0 Tannase and feruloyl esterase SLATT_fungal PF18142.1 KPI34864.1 - 3.7e-32 110.8 0.1 5e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain CCSAP PF15748.5 KPI34864.1 - 0.0064 16.7 3.5 0.0064 16.7 3.5 2.1 2 1 1 3 3 3 1 Centriole, cilia and spindle-associated SLATT_1 PF18181.1 KPI34864.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 TMEM208_SND2 PF05620.11 KPI34864.1 - 0.037 13.8 0.1 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Acetyltransf_3 PF13302.7 KPI34865.1 - 1.7e-23 83.8 0.0 2.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI34865.1 - 2.5e-11 43.8 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KPI34865.1 - 0.00029 21.0 0.0 0.00061 20.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPI34865.1 - 0.00056 19.6 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI34865.1 - 0.019 15.4 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DENN PF02141.21 KPI34866.1 - 5.4e-22 78.7 0.0 1.3e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KPI34866.1 - 0.0012 19.5 0.0 0.0036 18.0 0.0 1.9 1 0 0 1 1 1 1 uDENN domain DUF3540 PF12059.8 KPI34866.1 - 0.045 13.6 3.6 2 8.2 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3540) Spc7 PF08317.11 KPI34866.1 - 0.12 11.2 15.6 0.26 10.1 15.6 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein PCYCGC PF13798.6 KPI34866.1 - 0.18 11.6 2.5 0.42 10.5 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif ATG16 PF08614.11 KPI34866.1 - 1.2 9.3 24.0 2.5 8.3 13.4 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 KPI34866.1 - 2.2 7.4 12.9 0.64 9.2 8.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein GAS PF13851.6 KPI34866.1 - 3.8 6.8 21.4 33 3.7 21.4 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KPI34866.1 - 7.1 7.0 9.3 12 6.2 5.6 2.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 KPI34866.1 - 7.3 6.6 7.3 20 5.2 5.1 2.5 1 1 1 2 2 2 0 Sec20 Methyltransf_25 PF13649.6 KPI34867.1 - 4.5e-20 72.2 0.0 2.2e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI34867.1 - 1.3e-14 54.3 0.0 1.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI34867.1 - 1.5e-14 54.4 0.0 2.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI34867.1 - 2.7e-10 40.9 0.0 5.9e-10 39.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI34867.1 - 3.1e-10 40.2 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI34867.1 - 2.4e-07 30.5 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KPI34867.1 - 9.2e-06 25.9 0.0 2.5e-05 24.5 0.0 1.5 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KPI34867.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 KPI34867.1 - 0.0017 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPI34867.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KPI34867.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KPI34867.1 - 0.012 16.6 0.0 0.09 13.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KPI34867.1 - 0.047 13.0 0.0 0.091 12.0 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KPI34867.1 - 0.056 13.1 0.0 0.4 10.3 0.0 2.2 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 KPI34867.1 - 0.057 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SUZ-C PF12901.7 KPI34867.1 - 0.75 9.9 3.0 2.1 8.4 3.0 1.7 1 0 0 1 1 1 0 SUZ-C motif 2OG-FeII_Oxy_3 PF13640.6 KPI34868.1 - 2e-09 38.2 0.0 3.9e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1598 PF07643.11 KPI34869.1 - 0.048 13.9 0.2 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) adh_short PF00106.25 KPI34871.1 - 4.1e-34 117.8 0.0 6e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34871.1 - 5.9e-22 78.4 0.0 9.1e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI34871.1 - 2.5e-06 27.5 0.1 1.3e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI34871.1 - 0.0023 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1682 PF07946.14 KPI34872.1 - 0.17 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 KPI34873.1 - 1.4e-68 231.1 0.1 2.5e-68 230.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI34873.1 - 1.3e-31 109.9 0.0 1.9e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KPI34873.1 - 7.9e-12 45.7 1.7 7.9e-12 45.7 1.7 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KPI34873.1 - 1.4e-08 34.5 0.0 5.8e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KPI34873.1 - 2.8e-07 30.8 0.0 8.4e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KPI34873.1 - 0.00037 19.5 0.5 0.00037 19.5 0.5 1.9 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KPI34873.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KPI34873.1 - 0.0093 15.6 0.2 1.5 8.4 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KPI34873.1 - 0.066 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KPI34873.1 - 0.092 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.28 KPI34874.1 - 1.9e-69 234.3 0.0 2.8e-42 144.8 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KPI34874.1 - 6.5e-11 43.1 0.0 1.5e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KPI34875.1 - 9.1e-39 133.4 21.4 1.4e-38 132.7 21.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SnoaL_4 PF13577.6 KPI34876.1 - 2.3e-20 73.0 0.0 3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MMR_HSR1 PF01926.23 KPI34877.1 - 1.3e-06 28.5 3.2 2.9e-06 27.3 0.0 2.8 2 1 1 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 KPI34877.1 - 1.3e-05 24.6 0.0 1.3e-05 24.6 0.0 2.4 3 0 0 3 3 3 1 AIG1 family CRC_subunit PF08624.10 KPI34878.1 - 1.1e-49 168.3 0.0 1.8e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Transp_cyt_pur PF02133.15 KPI34879.1 - 7.6e-139 463.3 40.3 8.7e-139 463.1 40.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TPP_enzyme_N PF02776.18 KPI34880.1 - 7.6e-40 136.3 0.3 1.4e-39 135.5 0.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI34880.1 - 1.8e-34 118.5 0.0 4.1e-34 117.3 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain SR-25 PF10500.9 KPI34882.1 - 0.38 10.3 32.1 0.022 14.3 12.0 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Zn_clus PF00172.18 KPI34883.1 - 0.00027 21.0 9.2 0.00027 21.0 9.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_9 PF16293.5 KPI34883.1 - 0.016 15.0 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Cyclin PF08613.11 KPI34884.1 - 2.1e-08 34.7 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KPI34884.1 - 0.00036 20.3 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.16 KPI34885.1 - 2.8e-31 108.8 21.2 4.4e-31 108.1 21.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI34885.1 - 1.1e-07 31.2 3.4 1.1e-07 31.2 3.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TetR_N PF00440.23 KPI34886.1 - 0.031 14.1 0.1 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family TPP_enzyme_C PF02775.21 KPI34887.1 - 8e-15 54.9 1.2 2.6e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KPI34887.1 - 0.048 13.3 1.4 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MFS_1 PF07690.16 KPI34888.1 - 1.3e-35 123.0 35.2 1.3e-35 123.0 35.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 KPI34888.1 - 0.19 11.9 0.2 0.4 10.9 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Phage_holin_5_2 PF16079.5 KPI34888.1 - 2.7 8.4 13.6 0.62 10.4 0.5 4.2 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V Mcp5_PH PF12814.7 KPI34889.1 - 5.2e-08 33.0 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DREPP PF05558.12 KPI34889.1 - 0.17 11.7 1.6 0.29 11.0 1.6 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Fungal_trans PF04082.18 KPI34890.1 - 7.6e-29 100.6 2.1 9e-29 100.3 0.2 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI34890.1 - 5.9e-09 35.9 12.4 9.7e-09 35.2 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flag1_repress PF03614.13 KPI34890.1 - 0.074 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Methyltransf_2 PF00891.18 KPI34891.1 - 6.6e-21 74.6 0.0 1.2e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DUF3046 PF11248.8 KPI34891.1 - 0.094 13.1 0.0 3.4 8.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) E3_UFM1_ligase PF09743.9 KPI34891.1 - 0.25 10.9 0.0 0.48 10.0 0.0 1.4 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 tRNA-synt_1 PF00133.22 KPI34893.1 - 4.9e-192 639.4 0.0 9e-190 631.9 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Uso1_p115_head PF04869.14 KPI34893.1 - 1.3e-100 336.6 0.0 1e-99 333.6 0.0 2.2 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Anticodon_1 PF08264.13 KPI34893.1 - 1.3e-24 86.9 0.0 6.2e-23 81.4 0.0 2.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Uso1_p115_C PF04871.13 KPI34893.1 - 3.2e-18 66.3 28.8 3.2e-18 66.3 28.8 3.8 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region tRNA-synt_1g PF09334.11 KPI34893.1 - 1.3e-10 40.6 0.1 0.0013 17.6 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) HEAT PF02985.22 KPI34893.1 - 0.027 14.7 3.1 9.9 6.7 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat tRNA-synt_1e PF01406.19 KPI34893.1 - 0.04 13.3 0.0 0.04 13.3 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain FAM184 PF15665.5 KPI34893.1 - 1.4 8.6 51.0 0.0083 15.9 39.4 2.9 3 1 1 4 4 4 0 Family with sequence similarity 184, A and B adh_short_C2 PF13561.6 KPI34894.1 - 1.2e-52 178.8 0.1 1.5e-52 178.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI34894.1 - 6.8e-43 146.4 0.2 8e-43 146.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI34894.1 - 8.8e-09 35.5 0.1 1.3e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KPI34895.1 - 0.00026 19.9 0.0 0.0017 17.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain CorA PF01544.18 KPI34896.1 - 0.022 14.1 6.2 0.91 8.8 0.2 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF1330 PF07045.11 KPI34897.1 - 0.065 13.6 0.3 0.13 12.6 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1330) GTP1_OBG PF01018.22 KPI34898.1 - 3.3e-36 124.2 4.5 6.8e-29 100.5 4.6 2.7 2 1 1 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 KPI34898.1 - 3.1e-09 36.9 0.0 6.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Aspzincin_M35 PF14521.6 KPI34899.1 - 4.2e-05 24.1 0.7 0.22 12.1 0.0 3.3 3 0 0 3 3 3 3 Lysine-specific metallo-endopeptidase AAA PF00004.29 KPI34900.1 - 3.9e-40 137.3 0.1 9.9e-40 136.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPI34900.1 - 5e-17 61.6 0.2 1e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KPI34900.1 - 1.5e-08 34.3 0.0 4.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KPI34900.1 - 2e-05 24.6 0.1 7.7e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI34900.1 - 0.0001 22.7 2.0 0.019 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KPI34900.1 - 0.00026 20.8 0.0 0.00075 19.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KPI34900.1 - 0.00071 19.7 1.1 0.0031 17.7 0.0 2.5 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KPI34900.1 - 0.0026 18.1 1.5 0.096 13.0 0.0 2.9 2 1 0 3 3 3 1 AAA domain PhoH PF02562.16 KPI34900.1 - 0.0033 16.9 0.3 0.066 12.7 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KPI34900.1 - 0.0078 15.6 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KPI34900.1 - 0.009 15.2 0.9 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KPI34900.1 - 0.011 15.9 0.0 0.037 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KPI34900.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KPI34900.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KPI34900.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.9 2 2 0 3 3 2 0 AAA domain DnaJ PF00226.31 KPI34901.1 - 1.5e-14 53.9 0.5 4.2e-14 52.4 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KPI34901.1 - 8.8e-10 38.2 0.0 2.5e-08 33.4 0.0 2.7 2 1 0 2 2 2 1 Sec63 Brl domain PALP PF00291.25 KPI34903.1 - 2.6e-42 145.2 0.1 7.7e-29 101.0 0.1 2.2 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KPI34903.1 - 3.2e-13 49.9 0.0 2e-08 34.5 0.0 3.4 3 0 0 3 3 3 2 CBS domain F-box-like PF12937.7 KPI34904.1 - 0.0071 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KPI34904.1 - 0.014 15.8 4.5 3.4 8.2 0.2 4.7 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPI34904.1 - 0.031 14.3 6.6 0.31 11.2 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich repeat RRM_1 PF00076.22 KPI34905.1 - 1.6e-12 47.0 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI34905.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DAO PF01266.24 KPI34906.1 - 1.2e-34 120.5 0.3 2.5e-34 119.4 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI34906.1 - 6.5e-06 26.2 0.2 0.14 12.1 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI34906.1 - 0.00013 21.3 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI34906.1 - 0.00017 20.8 0.2 0.00064 18.9 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPI34906.1 - 0.00086 18.3 0.1 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KPI34906.1 - 0.0011 19.2 0.0 0.0039 17.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI34906.1 - 0.021 13.9 0.1 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KPI34906.1 - 0.028 15.0 0.1 3.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI34906.1 - 0.032 13.5 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KPI34906.1 - 0.049 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KPI34906.1 - 0.076 13.3 0.0 4.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Peptidase_S28 PF05577.12 KPI34908.1 - 2.1e-32 112.5 0.0 2.8e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KPI34908.1 - 6e-06 25.9 0.1 2.3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPI34908.1 - 5.8e-05 22.5 0.0 8.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KPI34908.1 - 0.0036 16.5 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KPI34908.1 - 0.045 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KPI34908.1 - 0.046 13.4 0.1 0.21 11.2 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Acetyltransf_10 PF13673.7 KPI34909.1 - 3e-10 40.1 0.1 1.4e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI34909.1 - 1.2e-09 38.5 0.2 3.4e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI34909.1 - 1.6e-08 34.8 0.0 3.5e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPI34909.1 - 2.9e-07 30.3 0.1 2.3e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KPI34909.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KPI34909.1 - 0.021 15.5 0.0 0.033 14.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPI34909.1 - 0.16 11.6 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2514 PF10721.9 KPI34910.1 - 0.025 14.6 6.2 0.054 13.5 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ABM PF03992.16 KPI34911.1 - 2.1e-08 34.2 0.0 4.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase p450 PF00067.22 KPI34912.1 - 2.1e-58 198.2 0.0 2.8e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cpn60_TCP1 PF00118.24 KPI34913.1 - 3e-153 511.0 6.2 3.5e-153 510.8 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KPI34913.1 - 0.12 12.8 0.0 14 6.2 0.0 2.8 2 0 0 2 2 2 0 Replication factor C C-terminal domain Forkhead PF00250.18 KPI34914.1 - 1.9e-14 53.7 0.0 3.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KPI34914.1 - 9.7e-06 25.8 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Prefoldin_2 PF01920.20 KPI34915.1 - 3.1e-16 59.3 12.9 4.5e-16 58.7 12.9 1.4 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 KPI34915.1 - 0.0013 19.0 9.2 0.0047 17.1 9.2 1.7 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Prefoldin_3 PF13758.6 KPI34915.1 - 0.011 15.8 0.9 0.011 15.8 0.9 1.4 1 1 0 1 1 1 0 Prefoldin subunit TPR_5 PF12688.7 KPI34915.1 - 0.017 15.4 0.4 0.036 14.3 0.4 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat Prefoldin PF02996.17 KPI34915.1 - 0.04 13.8 12.1 0.068 13.1 2.4 2.5 1 1 2 3 3 3 0 Prefoldin subunit End3 PF12761.7 KPI34915.1 - 0.041 14.1 8.0 0.057 13.6 8.0 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF484 PF04340.12 KPI34915.1 - 0.043 13.5 0.2 0.043 13.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DASH_Duo1 PF08651.10 KPI34915.1 - 0.071 12.9 2.2 1.3 8.9 0.5 2.5 2 1 0 2 2 2 0 DASH complex subunit Duo1 BioW PF03744.13 KPI34915.1 - 0.09 12.3 1.6 0.1 12.1 1.6 1.0 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase DHR10 PF18595.1 KPI34915.1 - 0.11 12.6 16.3 0.49 10.5 4.6 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain MscS_porin PF12795.7 KPI34915.1 - 0.11 12.0 19.5 0.34 10.4 4.7 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KPI34915.1 - 0.14 12.2 8.0 2.2 8.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KPI34915.1 - 0.16 12.2 8.0 0.56 10.5 0.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PHM7_cyt PF14703.6 KPI34915.1 - 0.38 11.0 3.0 0.95 9.7 3.0 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter YabA PF06156.13 KPI34915.1 - 0.81 10.4 8.4 4.4 8.0 0.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF4349 PF14257.6 KPI34915.1 - 0.84 9.0 14.1 0.24 10.8 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) FlaC_arch PF05377.11 KPI34915.1 - 1.1 9.8 6.3 13 6.3 0.1 3.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KPI34915.1 - 1.4 9.5 9.4 6.8 7.2 2.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 KPI34915.1 - 1.7 9.4 5.5 0.82 10.4 2.8 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tropomyosin_1 PF12718.7 KPI34915.1 - 1.7 8.8 13.4 1.3 9.2 2.1 2.2 2 0 0 2 2 2 0 Tropomyosin like Phage_GPO PF05929.11 KPI34915.1 - 2 8.0 8.7 4.4 6.8 1.9 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.9 KPI34915.1 - 2.7 7.0 7.2 4.2 6.4 7.2 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 KPI34915.1 - 3.6 7.9 9.7 71 3.7 9.7 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KPI34915.1 - 3.7 6.4 14.7 33 3.2 14.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 KPI34915.1 - 3.9 7.8 16.6 0.23 11.7 2.4 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain CorA PF01544.18 KPI34915.1 - 4.8 6.4 5.5 2.3 7.5 0.6 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Rx_N PF18052.1 KPI34915.1 - 5.4 7.3 8.3 1.8 8.9 2.3 2.2 2 1 0 2 2 2 0 Rx N-terminal domain AMP-binding PF00501.28 KPI34916.1 - 6.7e-62 209.4 0.0 8.5e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI34916.1 - 2.8e-13 50.6 0.1 5.7e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CC PF04942.14 KPI34917.1 - 0.0071 16.5 1.3 0.0071 16.5 1.3 2.3 2 0 0 2 2 2 1 CC domain Hairy_orange PF07527.13 KPI34918.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Hairy Orange B5 PF03484.15 KPI34919.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase B5 domain Mito_carr PF00153.27 KPI34921.1 - 1.3e-70 233.4 6.4 7.4e-24 83.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI34921.1 - 0.0015 17.8 2.2 0.042 13.0 0.0 3.1 2 1 0 3 3 3 2 Gammaproteobacterial serine protease IBR PF01485.21 KPI34922.1 - 4.8e-21 74.8 42.8 7.8e-11 42.0 2.2 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KPI34922.1 - 1.3e-05 25.4 1.4 1.3e-05 25.4 1.4 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI34922.1 - 8.1e-05 22.4 2.4 8.1e-05 22.4 2.4 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI34922.1 - 9.6e-05 22.3 2.0 9.6e-05 22.3 2.0 3.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI34922.1 - 0.00029 20.7 34.0 0.00058 19.7 3.0 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI34922.1 - 0.00039 20.3 5.3 0.00039 20.3 5.3 3.7 2 1 1 3 3 3 1 zinc-RING finger domain FRQ PF09421.10 KPI34923.1 - 5.4e-97 326.0 50.0 3e-92 310.3 34.3 4.7 2 2 0 3 3 3 3 Frequency clock protein COG4 PF08318.12 KPI34924.1 - 0.044 12.9 0.1 0.044 12.9 0.1 1.7 2 0 0 2 2 2 0 COG4 transport protein DAO PF01266.24 KPI34927.1 - 5e-07 29.6 0.1 0.00029 20.5 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPI34927.1 - 7.4e-05 22.1 1.3 0.17 11.1 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI34927.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI34927.1 - 0.03 14.9 0.0 0.082 13.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI34927.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.29 KPI34928.1 - 5.6e-42 143.3 0.0 9.3e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KPI34928.1 - 1.6e-29 101.7 0.1 7.8e-29 99.5 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KPI34928.1 - 7e-23 80.5 4.8 1.7e-22 79.3 4.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KPI34928.1 - 1.1e-05 25.1 0.0 4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KPI34928.1 - 1.1e-05 25.2 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI34928.1 - 1.5e-05 25.4 0.0 0.00021 21.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KPI34928.1 - 2e-05 24.8 0.1 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KPI34928.1 - 2.9e-05 24.1 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KPI34928.1 - 3.2e-05 23.3 0.0 5.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KPI34928.1 - 6.4e-05 23.3 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KPI34928.1 - 8.8e-05 22.3 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KPI34928.1 - 0.00013 22.3 0.1 0.019 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KPI34928.1 - 0.00032 19.9 0.0 0.0014 17.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KPI34928.1 - 0.00038 20.5 0.0 0.00073 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPI34928.1 - 0.00076 20.0 0.0 0.0022 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Torsin PF06309.11 KPI34928.1 - 0.0016 18.6 0.1 0.088 12.9 0.0 2.3 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.6 KPI34928.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPI34928.1 - 0.0039 16.9 0.1 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPI34928.1 - 0.007 16.0 0.3 0.53 9.8 0.1 2.9 3 1 0 4 4 4 1 AAA domain AAA_7 PF12775.7 KPI34928.1 - 0.011 15.3 0.0 0.078 12.5 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KPI34928.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KPI34928.1 - 0.027 13.9 0.0 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Use1 PF09753.9 KPI34928.1 - 0.056 13.2 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Parvo_NS1 PF01057.17 KPI34928.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KPI34928.1 - 0.061 13.2 0.1 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KPI34928.1 - 0.077 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KPI34928.1 - 0.084 12.8 0.0 0.7 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 KPI34928.1 - 0.14 11.9 0.9 0.53 10.0 0.0 2.3 2 1 2 4 4 4 0 Cytidylate kinase W2 PF02020.18 KPI34929.1 - 4.2e-18 65.3 1.8 1e-17 64.0 1.8 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KPI34929.1 - 4.6e-10 38.8 1.6 0.00085 19.0 0.3 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KPI34929.1 - 1.9e-07 30.9 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KPI34929.1 - 0.00032 21.1 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KPI34929.1 - 0.00086 19.0 4.8 0.86 9.4 2.8 2.8 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Metallophos_3 PF14582.6 KPI34929.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF4954 PF16314.5 KPI34929.1 - 0.1 10.7 0.2 1.9 6.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Vpu PF00558.19 KPI34929.1 - 0.23 11.3 3.9 0.52 10.1 3.9 1.6 1 0 0 1 1 1 0 Vpu protein Sugar_tr PF00083.24 KPI34930.1 - 1.2e-70 238.6 16.9 2.9e-44 151.7 1.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI34930.1 - 1.2e-09 37.6 11.7 1.2e-09 37.6 11.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KPI34931.1 - 4.8e-127 424.5 23.1 5.7e-127 424.2 23.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like VbhA PF18495.1 KPI34931.1 - 0.071 13.0 0.4 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Antitoxin VbhA Myb_DNA-binding PF00249.31 KPI34932.1 - 7.4e-13 48.5 1.6 1.7e-06 28.1 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPI34932.1 - 1.5e-07 31.5 0.8 0.0041 17.3 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Scytalone_dh PF02982.14 KPI34932.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Scytalone dehydratase p450 PF00067.22 KPI34933.1 - 2.9e-48 164.8 0.0 3.8e-34 118.2 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 SSF PF00474.17 KPI34934.1 - 3.8e-09 35.9 16.5 7.4e-09 34.9 16.5 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family adh_short PF00106.25 KPI34935.1 - 1.9e-20 73.1 0.0 2.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI34935.1 - 1.2e-16 60.9 0.0 2.7e-16 59.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KPI34935.1 - 0.11 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KPI34935.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 KPI34935.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 KPI34936.1 - 1.3e-37 129.2 0.0 2e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI34936.1 - 3e-08 33.4 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KPI34936.1 - 8.4e-07 28.9 0.0 5.3e-06 26.3 0.0 2.5 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KPI34936.1 - 2.4e-05 24.2 0.0 6.7e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPI34936.1 - 3.7e-05 24.0 0.2 0.00027 21.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI34936.1 - 0.00024 21.5 1.4 0.0087 16.5 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 KPI34936.1 - 0.00069 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KPI34936.1 - 0.00079 19.4 0.0 0.0022 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KPI34936.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KPI34936.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KPI34936.1 - 0.0047 16.3 0.1 0.0095 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KPI34936.1 - 0.024 14.8 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KPI34936.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KPI34936.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPI34936.1 - 0.04 14.5 0.0 0.093 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPI34936.1 - 0.041 13.5 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI34936.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPI34936.1 - 0.09 12.7 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KPI34936.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 KPI34936.1 - 0.16 11.6 0.0 0.54 9.9 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase PhoH PF02562.16 KPI34936.1 - 0.27 10.7 0.0 0.5 9.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Peptidase_C14 PF00656.22 KPI34938.1 - 4.1e-62 210.3 0.0 5.3e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KPI34938.1 - 0.14 12.2 0.6 0.72 9.8 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Aldedh PF00171.22 KPI34939.1 - 7.4e-14 51.1 8.1 1.5e-11 43.5 4.0 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Tfb5 PF06331.12 KPI34939.1 - 0.16 11.9 0.6 0.86 9.6 0.0 2.5 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 2OG-FeII_Oxy PF03171.20 KPI34940.1 - 2.7e-12 47.1 0.0 4.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPI34940.1 - 2e-10 41.5 0.0 3.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2335 PF10097.9 KPI34941.1 - 0.033 14.2 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Pil1 PF13805.6 KPI34942.1 - 1.1e-100 336.5 3.6 1.6e-100 336.0 3.6 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 KPI34942.1 - 0.29 11.7 14.9 0.3 11.6 6.7 2.5 3 0 0 3 3 3 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KPI34942.1 - 0.72 10.1 7.5 0.56 10.5 4.7 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain 2H-phosphodiest PF08975.10 KPI34943.1 - 7.5e-26 90.4 0.0 1.2e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) Mito_carr PF00153.27 KPI34944.1 - 3e-59 196.9 8.1 6.9e-24 83.6 0.3 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein 4HBT_3 PF13622.6 KPI34945.1 - 1.5e-78 264.5 3.5 2.3e-78 263.9 3.5 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KPI34945.1 - 3.7e-22 78.6 0.1 3.1e-12 46.5 0.0 4.5 4 1 0 4 4 4 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.6 KPI34945.1 - 0.074 12.8 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Bestrophin PF01062.21 KPI34945.1 - 0.66 9.3 2.1 0.84 9.0 0.6 1.7 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel CoA_trans PF01144.23 KPI34946.1 - 1e-103 345.4 2.6 3.9e-63 212.7 1.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DnaJ PF00226.31 KPI34947.1 - 1.9e-09 37.5 1.3 4.9e-09 36.2 1.3 1.8 1 1 0 1 1 1 1 DnaJ domain Inhibitor_I53 PF11714.8 KPI34947.1 - 0.14 12.4 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Arginase PF00491.21 KPI34948.1 - 2.4e-68 230.7 0.1 3.9e-68 230.0 0.1 1.3 1 0 0 1 1 1 1 Arginase family DUF3659 PF12396.8 KPI34948.1 - 2.4e-12 46.6 1.7 5.2e-12 45.5 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) 2OG-FeII_Oxy_3 PF13640.6 KPI34950.1 - 5.4e-11 43.2 0.0 1.1e-10 42.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribo_biogen_C PF04034.13 KPI34951.1 - 1.8e-24 85.8 1.0 4.6e-18 65.2 0.0 2.2 1 1 1 2 2 2 2 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KPI34951.1 - 1.7e-09 37.3 0.3 1.7e-09 37.3 0.3 1.9 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI zf-H2C2 PF09337.10 KPI34952.1 - 8.7e-15 54.7 1.7 1.4e-14 54.0 1.7 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KPI34952.1 - 4.1e-10 39.6 0.3 6.8e-10 38.9 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KPI34952.1 - 0.0003 21.0 0.0 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KPI34952.1 - 0.00095 19.9 0.0 0.0021 18.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI34952.1 - 0.0046 17.4 0.0 0.019 15.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPI34952.1 - 0.0058 16.8 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECR1_N PF14382.6 KPI34953.1 - 2.8e-13 49.4 0.0 6.6e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KPI34953.1 - 4.6e-06 26.9 0.1 1.8e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 KH domain EXOSC1 PF10447.9 KPI34953.1 - 0.0044 17.6 0.4 5.7 7.6 0.0 2.8 3 0 0 3 3 3 2 Exosome component EXOSC1/CSL4 Pmp3 PF01679.17 KPI34955.1 - 2.2e-13 50.2 4.6 3.4e-13 49.6 4.6 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CAP59_mtransfer PF11735.8 KPI34956.1 - 6.5e-74 248.7 0.0 8.1e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PAP2_3 PF14378.6 KPI34956.1 - 0.086 12.5 0.3 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 PAP2 superfamily UPF0203 PF05254.12 KPI34957.1 - 2.1e-27 95.1 0.7 2.4e-27 94.9 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KPI34957.1 - 0.00013 22.2 0.4 0.00025 21.3 0.4 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KPI34957.1 - 0.00059 19.8 1.6 0.027 14.5 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KPI34957.1 - 0.0016 18.6 1.5 0.36 11.1 0.0 2.1 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF4179 PF13786.6 KPI34957.1 - 0.065 13.7 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF5339 PF17274.2 KPI34957.1 - 0.51 11.2 2.0 2.7 8.9 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Ribosomal_L18 PF17135.4 KPI34959.1 - 6.6e-91 302.8 1.8 7.4e-91 302.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KPI34959.1 - 0.00011 22.9 0.1 0.00011 22.9 0.1 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A tRNA_anti-like PF12869.7 KPI34959.1 - 0.053 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like GatB_N PF02934.15 KPI34960.1 - 5.7e-93 311.2 0.0 7.3e-93 310.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KPI34960.1 - 7.1e-21 74.6 0.1 1.2e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 GatB domain COG2 PF06148.11 KPI34961.1 - 9.1e-24 84.1 0.0 1.9e-23 83.0 0.0 1.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KPI34961.1 - 2.5e-06 27.4 0.0 7.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Sigma70_ner PF04546.13 KPI34961.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-70, non-essential region TORC_M PF12885.7 KPI34961.1 - 0.13 12.2 2.5 0.21 11.5 2.5 1.3 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DNA_pol_phi PF04931.13 KPI34961.1 - 2.5 6.1 6.1 3.7 5.5 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Transp_cyt_pur PF02133.15 KPI34962.1 - 2.9e-100 336.1 34.7 3.3e-100 335.9 34.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Choline_transpo PF04515.12 KPI34964.1 - 3.6e-26 92.2 14.7 3.6e-26 92.2 14.7 2.5 2 2 0 2 2 2 1 Plasma-membrane choline transporter UPF0767 PF15990.5 KPI34964.1 - 4.8 7.4 4.5 3.3 7.9 1.5 2.2 2 0 0 2 2 2 0 UPF0767 family Ku PF02735.16 KPI34965.1 - 2.3e-27 96.0 0.0 3.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KPI34965.1 - 1.1e-23 83.6 0.0 2.7e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KPI34965.1 - 1.6e-08 34.6 0.0 3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KPI34965.1 - 0.00035 20.9 0.0 0.001 19.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Beta-lactamase PF00144.24 KPI34966.1 - 6.5e-54 183.4 0.0 8.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase FAD-oxidase_C PF02913.19 KPI34968.1 - 1.7e-59 201.5 0.0 4e-59 200.3 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPI34968.1 - 3.7e-38 130.4 0.2 6.3e-38 129.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Nudix_N PF12535.8 KPI34968.1 - 0.062 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal TRPM_tetra PF16519.5 KPI34969.1 - 0.018 15.2 0.8 0.028 14.5 0.8 1.3 1 0 0 1 1 1 0 Tetramerisation domain of TRPM NPV_P10 PF05531.12 KPI34969.1 - 0.039 14.4 0.1 0.059 13.8 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PhoR PF11808.8 KPI34969.1 - 0.051 14.0 3.4 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Laminin_II PF06009.12 KPI34969.1 - 0.054 13.5 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF4131 PF13567.6 KPI34969.1 - 0.17 11.5 2.7 1.7 8.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TssO PF17561.2 KPI34969.1 - 0.3 11.2 2.1 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF948 PF06103.11 KPI34969.1 - 0.4 11.0 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_holin_3_6 PF07332.11 KPI34969.1 - 7.5 6.6 15.2 13 5.9 1.3 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ParA PF10609.9 KPI34970.1 - 2.2e-83 279.5 1.0 1.2e-54 185.4 0.0 2.3 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KPI34970.1 - 2.5e-10 40.5 0.0 8.9e-10 38.7 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KPI34970.1 - 1.6e-06 27.6 0.0 1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KPI34970.1 - 4.2e-06 26.8 0.6 4.1e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KPI34970.1 - 5.2e-05 22.6 0.2 0.0001 21.6 0.2 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 KPI34970.1 - 0.00048 19.8 0.1 0.00092 18.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KPI34970.1 - 0.0019 17.3 0.2 0.0029 16.6 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KPI34970.1 - 0.0025 17.5 0.0 0.61 9.7 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_26 PF13500.6 KPI34970.1 - 0.0057 16.5 1.1 0.83 9.4 0.4 2.2 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KPI34970.1 - 0.0088 15.5 0.1 0.032 13.7 0.1 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 KPI34970.1 - 0.012 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KPI34970.1 - 0.058 12.8 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 KPI34970.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 KPI34970.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KPI34970.1 - 0.18 12.2 0.1 0.39 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain Alpha_GJ PF03229.13 KPI34970.1 - 0.28 11.8 2.8 0.16 12.5 0.7 1.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J RsgA_GTPase PF03193.16 KPI34970.1 - 0.36 10.7 1.2 0.82 9.6 1.2 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF917 PF06032.12 KPI34971.1 - 8.8e-102 340.5 0.2 1.8e-101 339.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KPI34971.1 - 1.4e-28 99.8 7.9 2e-26 92.8 0.0 3.9 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPI34971.1 - 3.2e-26 92.3 11.1 6.3e-24 84.7 1.2 3.4 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase MutL PF13941.6 KPI34971.1 - 0.00062 18.5 0.9 0.59 8.7 0.2 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 KPI34971.1 - 0.0039 16.7 2.8 0.0058 16.2 0.3 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 KPI34971.1 - 0.024 14.1 2.4 0.079 12.4 0.1 2.4 2 0 0 2 2 2 0 ROK family FtsZ_C PF12327.8 KPI34971.1 - 0.11 12.9 0.7 0.34 11.2 0.7 1.9 1 0 0 1 1 1 0 FtsZ family, C-terminal domain FtsA PF14450.6 KPI34971.1 - 0.46 10.9 3.5 1.8 9.0 0.0 3.2 4 0 0 4 4 4 0 Cell division protein FtsA CorA PF01544.18 KPI34972.1 - 1.1e-08 34.7 0.7 1.9e-08 34.0 0.7 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RPW8 PF05659.11 KPI34972.1 - 0.041 13.6 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BatD PF13584.6 KPI34972.1 - 0.16 10.8 0.5 0.23 10.2 0.5 1.2 1 0 0 1 1 1 0 Oxygen tolerance FMO-like PF00743.19 KPI34973.1 - 4.4e-20 71.6 0.0 3e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI34973.1 - 7.1e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI34973.1 - 1.4e-06 27.8 0.0 7.8e-06 25.4 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI34973.1 - 2.6e-05 23.5 0.0 0.0014 17.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI34973.1 - 0.00027 20.3 0.0 0.0017 17.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI34973.1 - 0.00099 18.5 0.0 0.18 11.1 0.1 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KPI34973.1 - 0.0016 18.5 0.2 0.072 13.1 0.0 3.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Ras PF00071.22 KPI34974.1 - 1e-50 171.5 0.2 2.6e-50 170.2 0.2 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPI34974.1 - 1.3e-29 102.9 0.1 8.9e-28 96.9 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI34974.1 - 3.1e-12 46.3 0.0 1e-10 41.3 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI34974.1 - 4.8e-09 36.0 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI34974.1 - 8.9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPI34974.1 - 0.00021 21.4 0.0 0.00072 19.6 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI34974.1 - 0.043 13.7 0.0 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase UPF0047 PF01894.17 KPI34977.1 - 4.1e-39 133.3 0.0 4.7e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 MFS_1 PF07690.16 KPI34978.1 - 1.6e-05 24.0 30.6 1.6e-05 24.0 30.6 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI34978.1 - 0.08 11.3 11.2 0.36 9.2 10.6 2.2 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF4235 PF14019.6 KPI34978.1 - 0.14 12.3 2.0 0.3 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) zf-CHCC PF10276.9 KPI34979.1 - 1.2e-14 54.1 3.4 2.1e-14 53.3 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain R3H PF01424.22 KPI34980.1 - 1.9e-10 40.6 0.1 3.7e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KPI34980.1 - 3.2e-06 26.8 0.0 6.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 KPI34980.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 HET PF06985.11 KPI34981.1 - 1e-24 87.6 0.0 3.4e-24 85.9 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_2 PF00152.20 KPI34982.1 - 1.3e-69 234.7 0.2 1.9e-69 234.2 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPI34982.1 - 1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HK97-gp10_like PF04883.12 KPI34982.1 - 0.75 10.8 6.3 5 8.2 2.7 3.0 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component TEBP_beta PF07404.11 KPI34982.1 - 6.8 5.9 12.4 5.1 6.3 9.9 1.9 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) HET PF06985.11 KPI34983.1 - 1.7e-32 112.7 0.2 3.1e-32 111.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KPI34984.1 - 5.9e-65 219.1 0.3 6.7e-65 218.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI34984.1 - 4.9e-54 182.8 0.2 6.3e-54 182.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI34984.1 - 7.7e-10 39.0 0.3 1.1e-09 38.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI34984.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rota_NSP4 PF01452.16 KPI34985.1 - 0.15 11.8 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Rotavirus non structural protein AA_permease PF00324.21 KPI34986.1 - 1.4e-142 475.7 45.8 1.7e-142 475.4 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI34986.1 - 1.2e-33 116.6 52.4 1.5e-33 116.3 52.4 1.1 1 0 0 1 1 1 1 Amino acid permease MPP6 PF10175.9 KPI34987.1 - 0.0015 19.1 8.4 0.0015 19.1 8.4 3.0 1 1 1 2 2 2 1 M-phase phosphoprotein 6 Med13_C PF06333.12 KPI34987.1 - 0.4 9.9 9.9 0.34 10.2 8.8 1.3 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Aldo_ket_red PF00248.21 KPI34988.1 - 1.8e-09 37.2 0.0 4.5e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family AIDA PF16168.5 KPI34988.1 - 0.088 12.9 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk Aldo_ket_red PF00248.21 KPI34989.1 - 1.2e-41 142.8 0.0 1.5e-32 113.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Catalase PF00199.19 KPI34990.1 - 2.5e-19 69.7 0.0 3e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 Catalase MFS_1 PF07690.16 KPI34991.1 - 2.1e-07 30.2 14.3 2.8e-07 29.8 13.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KPI34993.1 - 5.5e-14 51.8 0.2 1.5e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain TetR_C_27 PF17935.1 KPI34993.1 - 0.11 12.5 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Raffinose_syn PF05691.12 KPI34994.1 - 1.3e-45 155.6 3.2 1e-43 149.2 3.1 3.0 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 KPI34994.1 - 0.00053 19.0 1.6 0.0017 17.3 1.6 1.7 1 1 0 1 1 1 1 Melibiase DAO PF01266.24 KPI34995.1 - 2.5e-52 178.6 0.1 2.9e-52 178.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI34995.1 - 5.8e-06 26.4 0.2 1.4e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KPI34995.1 - 0.018 14.3 0.2 0.029 13.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KPI34995.1 - 0.02 14.2 0.2 0.03 13.6 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI34995.1 - 0.023 14.0 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KPI34995.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI34995.1 - 0.046 12.4 0.2 0.065 11.9 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KPI34995.1 - 0.054 12.7 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KPI34995.1 - 0.083 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KPI34995.1 - 0.096 13.3 0.2 0.19 12.3 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI34995.1 - 0.14 11.2 0.8 0.24 10.5 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KPI34995.1 - 0.2 10.7 0.2 0.31 10.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HSF_DNA-bind PF00447.17 KPI34997.1 - 4.4e-29 101.0 0.4 1.1e-28 99.7 0.4 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Spc7 PF08317.11 KPI34997.1 - 0.0091 14.9 1.1 0.024 13.5 1.1 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-C4H2 PF10146.9 KPI34997.1 - 0.022 15.1 0.5 0.022 15.1 0.5 3.2 3 0 0 3 3 3 0 Zinc finger-containing protein Ets PF00178.22 KPI34997.1 - 0.05 14.1 0.3 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Ets-domain APG6_N PF17675.1 KPI34997.1 - 0.98 9.9 5.2 3.2 8.3 0.2 3.3 4 0 0 4 4 4 0 Apg6 coiled-coil region DUF4407 PF14362.6 KPI34997.1 - 2.3 7.5 4.1 1.1 8.5 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 KPI34997.1 - 2.5 8.9 5.7 3.4 8.5 1.0 3.0 3 0 0 3 3 3 0 Occludin homology domain Histone PF00125.24 KPI34998.1 - 2.7e-17 63.4 0.0 3.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KPI34998.1 - 1.2e-12 47.4 0.1 2.4e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KPI34998.1 - 3.2e-05 24.1 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PX PF00787.24 KPI34999.1 - 1.5e-15 57.2 0.0 4.5e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 PX domain GDE_N_bis PF14742.6 KPI34999.1 - 0.091 12.3 1.7 5.9 6.4 0.9 3.0 2 1 0 2 2 2 0 N-terminal domain of (some) glycogen debranching enzymes T3SS_needle_reg PF09025.10 KPI34999.1 - 0.42 10.6 7.1 3.6 7.6 0.1 3.5 4 1 1 5 5 5 0 YopR, type III needle-polymerisation regulator Fungal_trans PF04082.18 KPI35000.1 - 6.7e-17 61.4 0.3 1e-16 60.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KPI35001.1 - 1.7e-07 30.6 0.6 4.7e-07 29.1 0.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35001.1 - 4.3e-06 26.7 8.8 8.4e-06 25.8 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4440 PF14534.6 KPI35004.1 - 0.0054 17.1 0.0 0.0067 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 KPI35004.1 - 0.15 12.7 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding DUF676 PF05057.14 KPI35005.1 - 7.8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KPI35005.1 - 0.00013 21.7 0.0 0.00045 20.0 0.0 1.8 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KPI35005.1 - 0.00019 22.1 0.0 0.00039 21.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KPI35005.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF3152 PF11350.8 KPI35005.1 - 0.019 14.7 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Hydrolase_4 PF12146.8 KPI35005.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ribonuc_P_40 PF08584.11 KPI35005.1 - 0.43 9.8 3.2 0.67 9.2 3.2 1.2 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Thioesterase PF00975.20 KPI35005.1 - 0.43 10.6 2.2 1.6 8.8 0.0 2.4 3 0 0 3 3 3 0 Thioesterase domain Ntox15 PF15604.6 KPI35005.1 - 0.48 10.5 6.9 0.81 9.8 6.9 1.3 1 0 0 1 1 1 0 Novel toxin 15 Spem1 PF15670.5 KPI35005.1 - 1.4 8.5 4.5 2.6 7.5 4.5 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Ifi-6-16 PF06140.13 KPI35006.1 - 2.5e-09 36.9 22.3 2.5e-09 36.9 22.3 1.8 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF4834 PF16118.5 KPI35007.1 - 0.079 13.9 0.0 0.24 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4690 PF15756.5 KPI35007.1 - 0.18 12.4 2.6 0.6 10.8 2.6 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 KPI35007.1 - 1.8 9.0 17.0 0.085 13.3 9.0 2.4 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 ADH_N PF08240.12 KPI35008.1 - 5.5e-21 74.5 2.0 1.1e-20 73.6 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI35008.1 - 1.2e-18 67.4 0.0 2.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI35008.1 - 1.5e-06 29.3 0.0 2.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KPI35009.1 - 5.7e-17 61.8 0.0 8.8e-17 61.2 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35009.1 - 9.4e-10 38.4 0.1 1.2e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI35009.1 - 8.4e-05 22.1 0.1 0.00085 18.8 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI35009.1 - 0.00028 20.8 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPI35009.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1518 PF07469.12 KPI35009.1 - 0.053 13.9 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) GDP_Man_Dehyd PF16363.5 KPI35009.1 - 0.27 10.6 0.9 5.8 6.2 0.4 2.5 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Rcd1 PF04078.13 KPI35010.1 - 7.6e-120 399.0 0.0 1.1e-119 398.5 0.0 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like GEP5 PF17053.5 KPI35010.1 - 0.0082 16.0 0.3 0.016 15.0 0.3 1.6 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 DUF1295 PF06966.12 KPI35011.1 - 5.3e-55 186.5 0.0 8.1e-55 185.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KPI35011.1 - 5.5e-07 29.7 0.4 4.6e-06 26.7 0.2 2.5 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KPI35011.1 - 0.00043 20.6 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KPI35011.1 - 0.019 15.3 0.6 0.3 11.5 0.0 2.8 3 0 0 3 3 3 0 Phospholipid methyltransferase YrhK PF14145.6 KPI35011.1 - 0.13 12.1 3.6 0.082 12.8 1.1 2.0 2 0 0 2 2 2 0 YrhK-like protein DJ-1_PfpI PF01965.24 KPI35012.1 - 3.1e-06 27.1 0.0 1.2e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KPI35012.1 - 0.0014 18.4 0.2 0.0051 16.5 0.1 2.1 2 1 0 2 2 2 1 ThiJ/PfpI family-like adh_short PF00106.25 KPI35013.1 - 4.6e-33 114.3 0.1 1e-25 90.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35013.1 - 4.3e-26 91.9 0.3 5.4e-17 62.1 0.2 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35013.1 - 7.2e-10 39.1 0.4 1.1e-09 38.5 0.4 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KPI35013.1 - 0.00032 21.0 0.2 0.00051 20.3 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI35013.1 - 0.031 13.8 0.1 0.044 13.2 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI35013.1 - 0.042 13.7 0.2 0.11 12.4 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KPI35013.1 - 0.084 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.8 KPI35014.1 - 3.7e-43 147.8 1.6 5.1e-43 147.3 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KPI35015.1 - 4.9e-11 42.2 0.1 8.8e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35015.1 - 1.8e-05 24.7 13.6 3.7e-05 23.7 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KPI35015.1 - 0.3 9.5 0.1 0.44 9.0 0.1 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B K_oxygenase PF13434.6 KPI35016.1 - 8.9e-12 44.8 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPI35016.1 - 1.3e-06 27.1 0.0 0.0008 17.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI35016.1 - 1.4e-06 27.8 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Proteasome PF00227.26 KPI35017.1 - 2e-56 190.5 0.2 2.7e-56 190.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPI35017.1 - 8.8e-13 47.7 0.2 2e-12 46.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosomal_L1 PF00687.21 KPI35018.1 - 9.3e-22 77.8 0.0 1.2e-21 77.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family SR-25 PF10500.9 KPI35018.1 - 0.009 15.6 2.6 0.013 15.1 2.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TPR_12 PF13424.6 KPI35019.1 - 3.8e-18 65.5 16.1 7.6e-08 32.5 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPI35019.1 - 2e-10 40.0 1.1 0.072 12.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35019.1 - 1.2e-08 34.4 11.1 0.0018 18.3 0.0 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KPI35019.1 - 7e-07 28.7 0.0 5.5e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 KPI35019.1 - 0.00014 21.6 20.2 0.029 14.2 1.6 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KPI35019.1 - 0.0017 18.8 0.0 0.013 15.9 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain TPR_8 PF13181.6 KPI35019.1 - 0.0021 18.1 10.0 2.7 8.4 0.1 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI35019.1 - 0.0026 17.7 2.8 0.92 9.7 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPI35019.1 - 0.0045 17.7 4.1 16 6.6 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI35019.1 - 0.022 15.4 0.7 13 6.7 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_35 PF14516.6 KPI35019.1 - 0.023 13.6 0.0 0.081 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain TPR_MalT PF17874.1 KPI35019.1 - 0.024 14.0 3.0 0.081 12.3 3.0 1.9 1 1 0 1 1 1 0 MalT-like TPR region ATPase_2 PF01637.18 KPI35019.1 - 0.16 11.8 0.0 7.6 6.4 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea zf-Di19 PF05605.12 KPI35019.1 - 0.6 10.4 7.8 1.1 9.6 2.0 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_M1 PF01433.20 KPI35021.1 - 1.6e-55 188.0 1.0 2.2e-50 171.2 0.2 2.4 1 1 1 2 2 2 2 Peptidase family M1 domain ERAP1_C PF11838.8 KPI35021.1 - 1.2e-46 159.7 1.5 1.8e-46 159.2 1.5 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KPI35021.1 - 4.4e-35 121.5 0.1 6.5e-35 121.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain RTP1_C1 PF10363.9 KPI35021.1 - 0.15 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Reprolysin_2 PF13574.6 KPI35021.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PMT PF02366.18 KPI35022.1 - 1.3e-85 286.9 19.1 1.3e-85 286.9 19.1 2.2 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KPI35022.1 - 1.9e-63 213.6 12.1 1.9e-63 213.6 12.1 3.1 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KPI35022.1 - 6.8e-35 120.6 0.3 1.1e-34 119.9 0.3 1.2 1 0 0 1 1 1 1 MIR domain TRIQK PF15168.6 KPI35022.1 - 0.15 11.9 0.6 13 5.8 0.2 2.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF2976 PF11190.8 KPI35022.1 - 9.3 6.1 6.7 1.6 8.5 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) BBS2_Mid PF14783.6 KPI35023.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 KPI35023.1 - 1 10.0 6.0 1 9.9 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain Nucleos_tra2_C PF07662.13 KPI35024.1 - 5.5e-72 242.0 1.6 5.5e-72 242.0 1.6 2.0 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KPI35024.1 - 1.9e-21 76.5 1.4 1.9e-21 76.5 1.4 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Lactonase PF10282.9 KPI35025.1 - 0.0029 16.9 0.1 0.11 11.7 0.0 2.6 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller TRI12 PF06609.13 KPI35026.1 - 1.3e-66 225.3 18.3 1.6e-66 225.0 18.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI35026.1 - 1.6e-24 86.6 56.6 9e-24 84.0 49.5 3.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35026.1 - 9.1e-16 57.7 3.6 9.1e-16 57.7 3.6 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter EamA PF00892.20 KPI35026.1 - 0.026 14.7 0.2 0.026 14.7 0.2 4.9 5 1 0 5 5 5 0 EamA-like transporter family DUF2417 PF10329.9 KPI35026.1 - 0.32 10.4 6.8 0.11 11.9 0.3 2.5 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Methyltransf_23 PF13489.6 KPI35027.1 - 2.3e-11 43.8 0.0 5.4e-11 42.6 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI35027.1 - 0.04 14.7 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-CHY PF05495.12 KPI35028.1 - 7.3e-14 52.0 16.4 1.2e-13 51.3 16.4 1.3 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_9 PF14369.6 KPI35028.1 - 0.017 15.3 6.6 0.053 13.8 3.9 2.4 1 1 1 2 2 2 0 zinc-ribbon zf_UBZ PF18439.1 KPI35028.1 - 0.018 14.6 5.0 3.2 7.4 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KPI35028.1 - 0.043 13.9 4.1 0.043 13.9 4.1 2.6 2 1 1 3 3 3 0 Zinc ribbon domain Cys_rich_KTR PF14205.6 KPI35028.1 - 0.16 11.8 5.3 4.3 7.2 1.8 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR DpnI PF06044.12 KPI35028.1 - 0.35 10.5 3.6 0.18 11.4 1.4 1.6 1 1 1 2 2 2 0 Dam-replacing family HypA PF01155.19 KPI35028.1 - 1.4 9.0 9.8 7.4 6.6 9.8 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Evr1_Alr PF04777.13 KPI35028.1 - 1.6 9.2 10.7 1.3e+02 3.2 10.7 2.8 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_10 PF10058.9 KPI35028.1 - 6.3 6.6 9.5 14 5.5 6.2 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein C1_4 PF07975.12 KPI35028.1 - 8.8 6.6 12.3 32 4.9 0.3 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain AA_permease PF00324.21 KPI35029.1 - 3.1e-138 461.4 36.2 3.5e-138 461.2 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI35029.1 - 2.1e-36 125.7 40.1 3.3e-36 125.1 40.1 1.3 1 0 0 1 1 1 1 Amino acid permease MKT1_C PF12246.8 KPI35030.1 - 0.0068 15.7 0.0 0.037 13.3 0.0 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication DZR PF12773.7 KPI35030.1 - 0.014 15.5 2.1 3.2 7.9 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon GFA PF04828.14 KPI35030.1 - 0.075 13.4 0.3 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc-ribbons_6 PF07191.12 KPI35030.1 - 0.13 12.2 2.0 4.4 7.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons DNA_ligase_ZBD PF03119.16 KPI35030.1 - 0.16 12.0 5.7 3.3 7.8 0.0 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DUF35_N PF12172.8 KPI35030.1 - 0.17 11.8 2.0 5.8 6.9 0.1 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 KPI35030.1 - 0.26 11.4 4.6 11 6.3 1.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DUF2367 PF10164.9 KPI35030.1 - 0.28 11.7 2.1 30 5.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2367) zf-ISL3 PF14690.6 KPI35030.1 - 0.33 11.7 5.3 11 6.8 0.6 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0547 PF10571.9 KPI35030.1 - 0.79 9.9 7.5 7.4 6.8 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 KPI35030.1 - 1.1 9.1 3.2 15 5.4 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain FAD_binding_3 PF01494.19 KPI35031.1 - 1.2e-18 67.5 0.0 4.7e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI35031.1 - 1.5e-06 28.3 0.2 3.4e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI35031.1 - 2.4e-05 23.7 0.4 0.00014 21.2 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI35031.1 - 0.00036 20.2 2.1 0.0063 16.1 0.6 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Mur_ligase PF01225.25 KPI35031.1 - 0.0017 18.7 0.3 0.12 12.7 0.1 2.5 2 0 0 2 2 2 1 Mur ligase family, catalytic domain AlaDh_PNT_C PF01262.21 KPI35031.1 - 0.0061 15.9 0.2 0.01 15.1 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KPI35031.1 - 0.007 15.5 0.3 0.01 14.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI35031.1 - 0.0081 14.9 0.3 0.013 14.3 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 KPI35031.1 - 0.085 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 KPI35031.1 - 0.097 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 KPI35031.1 - 0.17 11.8 0.1 0.7 9.8 0.1 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KPI35031.1 - 0.18 10.8 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KPI35031.1 - 0.24 12.0 3.0 0.45 11.1 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ank_4 PF13637.6 KPI35032.1 - 1.1e-58 194.9 0.8 2e-12 47.3 0.0 10.3 3 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI35032.1 - 1.9e-54 182.2 1.0 3.3e-11 43.6 0.0 6.1 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI35032.1 - 1e-51 172.3 4.3 1.7e-09 37.7 0.0 8.2 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI35032.1 - 1.1e-41 136.0 0.1 0.0015 18.8 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank PF00023.30 KPI35032.1 - 1.1e-36 123.7 5.0 0.0025 18.2 0.1 12.1 13 0 0 13 13 13 8 Ankyrin repeat Apolipoprotein PF01442.18 KPI35033.1 - 0.0037 17.2 42.9 0.0037 17.2 42.9 8.6 2 1 5 7 7 7 2 Apolipoprotein A1/A4/E domain Pox_A_type_inc PF04508.12 KPI35033.1 - 0.45 10.5 2.9 11 6.0 0.1 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Rsa3 PF14615.6 KPI35033.1 - 0.72 9.5 3.3 1.9 8.1 0.0 3.6 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Filament PF00038.21 KPI35033.1 - 1.5 8.3 176.1 0.016 14.8 12.5 9.4 1 1 7 8 8 8 0 Intermediate filament protein PfUIS3 PF11567.8 KPI35033.1 - 4.9 7.6 9.9 0.096 13.0 0.6 3.0 3 0 0 3 3 3 0 Plasmodium falciparum UIS3 membrane protein YmgD PF16456.5 KPI35033.1 - 8.1 6.6 8.8 2 8.5 0.4 4.0 3 0 0 3 3 3 0 YmgD protein MIF4G_like_2 PF09090.11 KPI35034.1 - 0.36 10.2 4.0 1 8.8 4.0 1.7 1 0 0 1 1 1 0 MIF4G like DUF4407 PF14362.6 KPI35034.1 - 7.4 5.8 16.7 0.24 10.7 10.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Aldedh PF00171.22 KPI35035.1 - 3.4e-14 52.2 1.4 1e-07 30.9 0.0 3.1 2 1 1 3 3 3 3 Aldehyde dehydrogenase family Herpes_UL14 PF03580.14 KPI35035.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ATG7_N PF16420.5 KPI35036.1 - 2.7e-101 339.2 0.0 3.4e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KPI35036.1 - 3.8e-47 160.7 0.0 6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KPI35036.1 - 0.0079 16.3 0.0 0.51 10.4 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Peptidase_S15 PF02129.18 KPI35037.1 - 9.6e-41 140.1 0.0 1.4e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KPI35037.1 - 1.7e-40 139.3 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KPI35037.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_GDSL_2 PF13472.6 KPI35038.1 - 6.6e-20 72.2 0.1 1.5e-19 71.1 0.0 1.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPI35038.1 - 4.1e-11 43.2 0.0 2.9e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.22 KPI35039.1 - 3.1e-47 161.4 0.0 5.8e-40 137.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Thioredoxin PF00085.20 KPI35041.1 - 1.1e-62 208.4 4.9 5.5e-29 100.2 0.0 4.5 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.6 KPI35041.1 - 9.4e-51 172.3 0.2 2.1e-39 135.4 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KPI35041.1 - 1.8e-12 47.0 0.3 4.3e-12 45.8 0.3 1.6 1 1 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 KPI35041.1 - 3.3e-08 33.2 0.4 0.0025 17.2 0.0 3.2 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KPI35041.1 - 4.2e-08 33.2 0.0 0.0067 16.6 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KPI35041.1 - 5.7e-08 33.0 0.1 0.063 13.6 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KPI35041.1 - 7.2e-08 32.8 1.0 0.021 15.3 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KPI35041.1 - 7.8e-07 29.1 1.3 0.014 15.3 0.0 3.3 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 KPI35041.1 - 0.0019 18.0 5.9 0.16 11.7 0.0 3.7 4 0 0 4 4 4 2 Redoxin Thioredoxin_3 PF13192.6 KPI35041.1 - 0.043 13.9 0.1 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain CPSase_sm_chain PF00988.22 KPI35041.1 - 0.18 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Thioredoxin_4 PF13462.6 KPI35041.1 - 0.43 10.7 5.9 8.2 6.6 0.6 3.8 2 2 0 2 2 2 0 Thioredoxin Sugar_tr PF00083.24 KPI35042.1 - 5.2e-118 394.8 24.5 5.9e-118 394.6 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35042.1 - 8.9e-26 90.6 54.2 2.4e-24 85.9 25.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FAA_hydrolase PF01557.18 KPI35043.1 - 2.9e-51 174.2 0.0 4.4e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPI35043.1 - 3.4e-18 65.8 0.1 5.4e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal NOC3p PF07540.11 KPI35044.1 - 9.5e-25 86.9 0.0 9.5e-25 86.9 0.0 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KPI35044.1 - 2.9e-18 66.5 0.0 2.9e-18 66.5 0.0 2.4 3 1 0 3 3 3 1 CBF/Mak21 family DUF4455 PF14643.6 KPI35044.1 - 0.019 13.6 4.0 0.033 12.9 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) PRC2_HTH_1 PF18118.1 KPI35044.1 - 1.6 9.6 7.9 6.4 7.6 0.2 3.3 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Sua5_yciO_yrdC PF01300.18 KPI35045.1 - 3.3e-14 52.8 0.0 4.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination adh_short_C2 PF13561.6 KPI35046.1 - 8.6e-56 189.1 2.2 1.3e-55 188.5 2.2 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35046.1 - 1e-52 178.5 2.3 1.3e-52 178.1 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35046.1 - 4.9e-14 52.6 0.8 8e-14 52.0 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI35046.1 - 0.0053 16.2 0.2 0.016 14.7 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DegV PF02645.16 KPI35046.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 DUF1776 PF08643.10 KPI35046.1 - 0.23 10.8 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.18 KPI35047.1 - 1.9e-05 24.7 11.6 3.4e-05 23.9 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPI35048.1 - 2.2e-21 76.2 44.6 2.2e-21 76.2 44.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI35048.1 - 4.7e-17 61.6 25.8 4.6e-16 58.4 25.8 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4917 PF16263.5 KPI35050.1 - 0.067 12.5 0.1 0.076 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) Cwf_Cwc_15 PF04889.12 KPI35052.1 - 1.2e-85 287.2 16.7 1.4e-85 287.0 16.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KPI35052.1 - 0.14 10.3 15.8 0.16 10.2 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KPI35052.1 - 2.5 6.3 16.6 3 6.0 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KPI35052.1 - 4.2 6.0 5.6 5.2 5.7 5.6 1.1 1 0 0 1 1 1 0 Presenilin AA_permease_2 PF13520.6 KPI35053.1 - 1.6e-42 145.8 57.8 2e-42 145.5 57.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI35053.1 - 9.7e-16 57.4 47.2 1.3e-15 57.0 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_12 PF13087.6 KPI35054.1 - 1.6e-36 125.8 0.0 2.6e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPI35054.1 - 3.7e-25 89.2 0.0 9.9e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI35054.1 - 2.2e-10 41.1 0.0 1.8e-09 38.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI35054.1 - 4.8e-08 32.9 0.3 0.00024 20.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain zf-CCCH_4 PF18044.1 KPI35054.1 - 5.9e-07 29.2 5.4 1.4e-06 27.9 5.4 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KPI35054.1 - 1.6e-06 27.9 7.8 3.8e-06 26.8 7.8 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KPI35054.1 - 4.5e-05 24.1 0.5 0.00015 22.4 0.8 1.7 2 0 0 2 2 1 1 Torus domain zf-CCCH PF00642.24 KPI35054.1 - 0.0001 22.1 5.6 0.0001 22.1 5.6 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2075 PF09848.9 KPI35054.1 - 0.0025 17.1 0.2 0.07 12.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KPI35054.1 - 0.0031 17.9 0.2 0.086 13.2 0.2 2.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KPI35054.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein L_lactis_RepB_C PF06430.12 KPI35054.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus DEAD PF00270.29 KPI35054.1 - 0.17 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Baculo_PEP_C PF04513.12 KPI35055.1 - 0.0005 20.1 10.8 0.11 12.5 0.2 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.14 KPI35055.1 - 0.0014 18.1 0.9 0.0023 17.3 0.9 1.3 1 0 0 1 1 1 1 Dynamitin DUF1664 PF07889.12 KPI35055.1 - 0.013 15.5 1.0 3.5 7.7 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KPI35055.1 - 0.015 15.5 0.1 12 6.3 0.2 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain XhlA PF10779.9 KPI35055.1 - 0.022 14.9 1.8 0.42 10.9 0.0 3.1 3 0 0 3 3 3 0 Haemolysin XhlA Exonuc_VII_L PF02601.15 KPI35055.1 - 0.031 13.8 0.4 0.065 12.8 0.4 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 KPI35055.1 - 0.074 13.5 3.0 0.26 11.8 0.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Spc19 PF08287.11 KPI35055.1 - 0.098 12.5 2.5 0.88 9.5 1.7 2.7 1 1 1 2 2 2 0 Spc19 CLZ PF16526.5 KPI35055.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 KPI35055.1 - 0.19 12.1 0.7 1.6 9.1 0.0 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 KPI35055.1 - 0.65 10.3 3.7 1.9 8.9 3.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.20 KPI35055.1 - 1.2 9.1 3.7 21 5.1 1.9 2.8 2 1 1 3 3 3 0 Prefoldin subunit SlyX PF04102.12 KPI35055.1 - 1.5 9.5 9.9 2.5 8.8 0.1 3.2 3 1 1 4 4 3 0 SlyX PilJ PF13675.6 KPI35055.1 - 1.7 8.7 5.0 1.5 8.8 1.8 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Laminin_II PF06009.12 KPI35055.1 - 4.4 7.3 6.3 0.6 10.1 0.3 2.5 2 1 1 3 3 3 0 Laminin Domain II SnoaL_2 PF12680.7 KPI35056.1 - 1.2e-06 29.1 0.8 1.7e-06 28.6 0.8 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KPI35056.1 - 1.4e-06 28.1 0.1 1.9e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Med22 PF06179.12 KPI35058.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex zf-C2H2_6 PF13912.6 KPI35059.1 - 1.9e-07 30.9 21.4 0.16 12.0 0.2 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KPI35059.1 - 2.8e-05 24.6 35.5 0.15 13.0 1.4 6.6 5 1 1 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI35059.1 - 0.00053 20.3 42.2 0.043 14.3 0.9 6.6 6 1 0 6 6 6 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 KPI35059.1 - 0.0021 18.7 22.4 0.099 13.3 0.1 4.6 3 2 1 4 4 4 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KPI35059.1 - 0.015 15.6 12.9 0.2 12.0 3.7 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 KPI35059.1 - 0.072 13.5 14.9 11 6.6 0.5 5.7 5 2 0 5 5 5 0 Zinc-finger of C2H2 type DHHC PF01529.20 KPI35060.1 - 2e-31 108.9 3.9 2e-31 108.9 3.9 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 KPI35060.1 - 1.7 8.7 10.6 3.6 7.7 10.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Helicase_C PF00271.31 KPI35061.1 - 2e-11 44.2 0.2 6.5e-11 42.6 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI35061.1 - 2.1e-09 37.4 0.0 4.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2388 PF09498.10 KPI35061.1 - 0.061 13.3 0.2 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Melibiase PF02065.18 KPI35062.1 - 1.1e-116 389.6 0.0 1.5e-116 389.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KPI35062.1 - 4.5e-76 255.7 0.0 6.1e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain GHL10 PF02638.15 KPI35062.1 - 0.00099 18.3 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 HK PF02110.15 KPI35063.1 - 4.6e-80 268.6 1.0 5.2e-80 268.4 1.0 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KPI35063.1 - 0.00015 21.3 0.3 0.00023 20.7 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KPI35063.1 - 0.0002 20.8 0.0 0.0003 20.3 0.0 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.16 KPI35064.1 - 5.8e-13 48.5 54.6 2.2e-10 40.0 52.1 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KPI35065.1 - 3.4e-11 42.7 0.6 5.2e-11 42.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_36C PF16874.5 KPI35067.1 - 3e-20 72.5 0.0 4.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain Melibiase PF02065.18 KPI35067.1 - 0.00068 18.7 0.0 0.00086 18.4 0.0 1.1 1 0 0 1 1 1 1 Melibiase UPF0113_N PF17833.1 KPI35069.1 - 3e-25 88.6 0.0 4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KPI35069.1 - 5.9e-23 80.9 0.0 1.5e-22 79.6 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain PUA PF01472.20 KPI35069.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 PUA domain MFS_1 PF07690.16 KPI35071.1 - 3.5e-27 95.3 31.0 3.9e-27 95.1 29.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35071.1 - 3.1e-06 26.3 13.9 6.6e-06 25.2 12.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KPI35071.1 - 0.001 18.0 0.8 0.001 18.0 0.8 2.2 2 0 0 2 2 2 1 MFS_1 like family FixQ PF05545.11 KPI35071.1 - 0.82 9.7 0.0 0.82 9.7 0.0 3.3 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ LigB PF02900.18 KPI35072.1 - 2.6e-16 59.5 0.0 3e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_M14 PF00246.24 KPI35073.1 - 6e-14 52.5 0.0 9.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KPI35073.1 - 0.001 18.3 0.1 0.003 16.7 0.0 1.8 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family eIF-5_eIF-2B PF01873.17 KPI35074.1 - 3.8e-39 133.2 0.0 8.3e-39 132.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KPI35074.1 - 6.1e-21 74.3 0.0 1.7e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Elf1 PF05129.13 KPI35074.1 - 2.4 8.3 4.5 0.95 9.6 0.3 2.5 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Cupin_2 PF07883.11 KPI35075.1 - 9.3e-08 31.7 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KPI35075.1 - 0.097 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Rhomboid PF01694.22 KPI35076.1 - 0.00032 20.7 6.3 0.037 14.0 1.0 3.2 3 0 0 3 3 3 2 Rhomboid family Voltage_CLC PF00654.20 KPI35077.1 - 4.5e-78 263.0 35.4 2.7e-51 174.9 12.2 2.6 2 1 1 3 3 3 2 Voltage gated chloride channel DUF4605 PF15378.6 KPI35077.1 - 0.74 9.7 0.0 0.74 9.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4605) TMP-TENI PF02581.17 KPI35078.1 - 2.4e-49 167.1 0.1 2.9e-49 166.9 0.1 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase Methyltransf_3 PF01596.17 KPI35079.1 - 1.1e-29 103.2 0.0 1.4e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KPI35079.1 - 2.8e-13 50.8 0.0 4.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPI35079.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KPI35079.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KPI35079.1 - 0.048 14.4 0.0 0.1 13.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KPI35079.1 - 0.062 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 KPI35079.1 - 0.12 12.1 0.1 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase CmcI PF04989.12 KPI35079.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase ABC2_membrane PF01061.24 KPI35080.1 - 3.4e-64 216.1 63.5 2.7e-41 141.3 29.2 3.9 4 1 1 5 5 4 3 ABC-2 type transporter PDR_CDR PF06422.12 KPI35080.1 - 1.8e-35 120.7 1.9 5.5e-30 103.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KPI35080.1 - 9.3e-33 113.6 0.0 2.5e-16 60.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.6 KPI35080.1 - 1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KPI35080.1 - 8.1e-09 35.8 0.1 1.4e-05 25.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPI35080.1 - 5.7e-08 33.3 0.5 2.9e-05 24.5 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KPI35080.1 - 2e-06 28.4 0.1 0.00016 22.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI35080.1 - 1.6e-05 24.9 0.1 0.00066 19.6 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 KPI35080.1 - 0.00018 21.2 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPI35080.1 - 0.00024 20.8 1.0 0.025 14.3 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 KPI35080.1 - 0.00027 21.4 0.1 0.022 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI35080.1 - 0.00057 20.2 0.1 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPI35080.1 - 0.0015 18.5 0.1 0.24 11.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 KPI35080.1 - 0.012 15.4 0.1 2 8.2 0.1 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KPI35080.1 - 0.013 15.3 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KPI35080.1 - 0.02 15.3 0.2 7.7 6.9 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KPI35080.1 - 0.027 14.1 0.6 0.24 11.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPI35080.1 - 0.076 12.7 0.2 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Nrap_D5 PF17406.2 KPI35080.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 AAA_28 PF13521.6 KPI35080.1 - 0.12 12.6 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KPI35080.1 - 0.18 11.2 0.0 12 5.3 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Tudor_3 PF18115.1 KPI35082.1 - 0.0002 21.2 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Fis1_TPR_C PF14853.6 KPI35082.1 - 0.0048 16.9 0.2 0.009 16.1 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat LBR_tudor PF09465.10 KPI35082.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain TUDOR PF00567.24 KPI35082.1 - 0.021 14.8 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Tudor domain DUF1192 PF06698.11 KPI35082.1 - 0.027 14.5 0.1 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FlxA PF14282.6 KPI35082.1 - 0.028 14.4 0.2 0.058 13.4 0.2 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF4537 PF15057.6 KPI35082.1 - 0.054 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) CENP-Q PF13094.6 KPI35082.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit MFS_1 PF07690.16 KPI35084.1 - 1.2e-32 113.2 41.5 1.2e-32 113.2 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KPI35084.1 - 0.063 13.5 0.2 0.063 13.5 0.2 4.0 5 0 0 5 5 5 0 Transglycosylase associated protein DUF4179 PF13786.6 KPI35084.1 - 0.18 12.3 4.3 19 5.8 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Isochorismatase PF00857.20 KPI35085.1 - 7.6e-23 81.6 0.2 9e-23 81.3 0.2 1.0 1 0 0 1 1 1 1 Isochorismatase family Terminase_1 PF03354.15 KPI35085.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase NmrA PF05368.13 KPI35086.1 - 2e-27 96.3 0.0 4.2e-27 95.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI35086.1 - 2.9e-18 66.4 0.0 4.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI35086.1 - 2.1e-05 24.1 0.5 5e-05 22.9 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI35086.1 - 0.00043 19.5 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KPI35086.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPI35086.1 - 0.007 15.5 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 KPI35086.1 - 0.029 13.8 1.3 0.18 11.3 0.2 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Anp1 PF03452.14 KPI35087.1 - 1e-95 320.2 0.0 1.6e-95 319.5 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_4 PF13704.6 KPI35087.1 - 0.037 14.5 1.1 0.069 13.7 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Rad54_N PF08658.10 KPI35087.1 - 0.45 10.7 3.7 0.24 11.6 1.5 1.6 2 0 0 2 2 2 0 Rad54 N terminal Ferlin_C PF16165.5 KPI35087.1 - 0.45 10.4 1.6 0.85 9.6 1.6 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Thioredoxin PF00085.20 KPI35088.1 - 4.6e-28 97.2 0.1 5.5e-28 97.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPI35088.1 - 7.4e-06 26.4 0.1 1.6e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KPI35088.1 - 4.8e-05 23.6 0.0 0.0022 18.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KPI35088.1 - 0.00044 19.7 0.0 0.00056 19.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KPI35088.1 - 0.0011 18.9 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KPI35088.1 - 0.047 13.9 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KPI35088.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin ADH_N PF08240.12 KPI35089.1 - 1.7e-07 31.0 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI35089.1 - 4.5e-06 26.7 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI35089.1 - 0.0018 19.3 0.0 0.0046 18.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF5532 PF17673.1 KPI35090.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5532) Cupin_1 PF00190.22 KPI35091.1 - 1.3e-05 24.8 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPI35091.1 - 2.9e-05 23.7 0.9 2.9e-05 23.7 0.9 2.1 2 1 0 2 2 2 1 Cupin domain Adaptin_N PF01602.20 KPI35092.1 - 8.8e-103 344.6 0.2 1e-102 344.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPI35092.1 - 1.4e-16 61.0 0.6 4.7e-15 56.0 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KPI35092.1 - 3.6e-07 29.9 0.5 0.13 12.6 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KPI35092.1 - 1.5e-05 25.3 9.1 0.00013 22.3 0.0 4.9 5 1 1 6 6 6 1 HEAT repeats Cohesin_HEAT PF12765.7 KPI35092.1 - 0.00011 22.4 1.0 0.2 12.0 0.0 3.4 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion SPO22 PF08631.10 KPI35092.1 - 0.00024 20.7 4.2 0.022 14.3 0.6 3.8 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like EH_Signature PF15611.6 KPI35092.1 - 0.0025 17.3 0.1 0.014 14.9 0.1 1.9 1 1 1 2 2 2 1 EH_Signature domain TruB_C PF09142.11 KPI35092.1 - 0.04 13.7 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal CRISPR_Cse2 PF09485.10 KPI35092.1 - 0.053 14.0 0.3 1.4 9.5 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) RNA_pol_3_Rpc31 PF11705.8 KPI35092.1 - 0.85 9.8 15.1 1.5 9.0 15.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_hydro_125 PF06824.11 KPI35093.1 - 3.8e-92 309.3 0.0 4.5e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) HORMA PF02301.18 KPI35094.1 - 2.6e-12 46.8 0.0 4.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain ChitinaseA_N PF08329.10 KPI35095.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Chitinase A, N-terminal domain JAB PF01398.21 KPI35096.1 - 4e-26 91.3 0.0 1e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KPI35096.1 - 6.4e-19 68.7 0.1 1.1e-18 67.9 0.1 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KPI35096.1 - 0.0023 17.7 0.0 0.0071 16.1 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.12 KPI35097.1 - 1.2e-70 238.9 23.1 1.2e-70 238.9 23.1 3.0 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.12 KPI35097.1 - 0.0013 18.8 0.6 0.0056 16.7 0.3 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 KPI35097.1 - 0.0079 16.7 3.7 0.18 12.3 0.8 3.3 2 0 0 2 2 2 1 Spectrin repeat Fungal_trans PF04082.18 KPI35098.1 - 2.6e-11 43.1 0.5 6.2e-11 41.8 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KPI35099.1 - 5.2e-26 92.1 0.0 6.3e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI35099.1 - 0.0019 18.4 0.0 0.0052 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KPI35099.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 KPI35099.1 - 0.032 13.5 0.0 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI35099.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI35099.1 - 0.16 11.0 0.1 0.22 10.6 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KPI35099.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 KPI35100.1 - 3.4e-24 86.4 0.0 8.5e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.8 KPI35100.1 - 1.5e-08 33.8 3.1 2.7e-08 33.1 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF829 PF05705.14 KPI35101.1 - 7.2e-41 140.7 0.1 9.3e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Golgin_A5 PF09787.9 KPI35102.1 - 0.12 11.8 2.3 0.22 10.9 2.3 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Aldedh PF00171.22 KPI35103.1 - 1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Vinculin PF01044.19 KPI35103.1 - 0.12 10.5 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Vinculin family ThiF PF00899.21 KPI35104.1 - 3.8e-43 147.6 0.1 1.1e-42 146.0 0.0 1.7 2 0 0 2 2 2 1 ThiF family Sacchrp_dh_NADP PF03435.18 KPI35104.1 - 0.00033 20.9 0.6 0.072 13.4 0.2 2.6 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KPI35104.1 - 0.0053 17.0 0.6 0.031 14.5 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain DUF5073 PF16817.5 KPI35104.1 - 0.01 15.9 0.1 0.042 13.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5073) UDPG_MGDP_dh_N PF03721.14 KPI35104.1 - 0.011 15.3 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KPI35104.1 - 0.018 15.5 0.8 0.064 13.7 0.8 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Tubulin_2 PF13809.6 KPI35104.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Pro_dh PF01619.18 KPI35105.1 - 1.2e-45 156.3 0.0 1.6e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase IBN_N PF03810.19 KPI35107.1 - 1e-05 25.4 0.1 5.6e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 KPI35107.1 - 0.01 16.0 1.0 38 4.9 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat Xpo1 PF08389.12 KPI35107.1 - 0.015 15.4 0.0 1.1 9.3 0.0 4.0 4 1 0 4 4 4 0 Exportin 1-like protein CAS_CSE1 PF03378.15 KPI35107.1 - 0.033 12.7 0.1 0.067 11.7 0.1 1.5 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Ribonuc_red_sm PF00268.21 KPI35108.1 - 1.2e-121 405.5 0.7 1.4e-121 405.2 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Acetyltransf_1 PF00583.25 KPI35109.1 - 0.0023 18.2 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI35109.1 - 0.096 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FA_desaturase PF00487.24 KPI35110.1 - 2.2e-31 109.6 26.4 3.2e-31 109.1 26.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase COPI_assoc PF08507.10 KPI35111.1 - 3e-25 88.8 4.1 3.3e-25 88.6 4.1 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2583 PF10762.9 KPI35111.1 - 0.18 12.3 4.2 0.39 11.2 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Mannosyl_trans3 PF11051.8 KPI35112.1 - 2.7e-58 197.5 0.1 8.1e-37 127.1 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative DUF3772 PF12607.8 KPI35112.1 - 0.048 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Aldedh PF00171.22 KPI35114.1 - 1.6e-40 139.0 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 KPI35114.1 - 0.22 11.4 0.3 0.6 10.0 0.1 1.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) adh_short PF00106.25 KPI35115.1 - 1.9e-28 99.3 0.0 3.6e-28 98.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35115.1 - 3.7e-23 82.3 0.0 5.8e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI35115.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KPI35115.1 - 0.15 12.1 0.2 0.4 10.7 0.2 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4211 PF13926.6 KPI35117.1 - 5.6e-37 127.0 0.1 2.7e-36 124.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) SPT6_acidic PF14632.6 KPI35117.1 - 0.0082 16.7 8.9 0.0082 16.7 8.9 5.3 4 1 2 6 6 6 2 Acidic N-terminal SPT6 CDC27 PF09507.10 KPI35118.1 - 3.6e-71 240.8 43.5 4.1e-71 240.6 43.5 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Prefoldin PF02996.17 KPI35121.1 - 4.2e-23 81.5 0.0 5.4e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KPI35121.1 - 0.0057 16.6 0.4 0.2 11.7 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit Fib_alpha PF08702.10 KPI35121.1 - 0.0091 16.2 1.5 0.41 10.8 0.1 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DASH_Dad2 PF08654.10 KPI35121.1 - 0.019 15.4 1.0 4.5 7.8 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 FAP206 PF12018.8 KPI35121.1 - 0.022 14.3 1.5 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function Med30 PF11315.8 KPI35121.1 - 0.063 13.5 0.4 7.8 6.7 0.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 Mst1_SARAH PF11629.8 KPI35121.1 - 0.11 12.6 0.5 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 WXG100 PF06013.12 KPI35121.1 - 0.14 12.4 0.8 14 6.0 0.0 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Imm3 PF14425.6 KPI35121.1 - 0.18 11.8 0.7 0.62 10.1 0.2 1.9 2 0 0 2 2 2 0 Immunity protein Imm3 DUF1664 PF07889.12 KPI35121.1 - 0.25 11.4 2.2 5.8 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pilt PF15453.6 KPI35121.1 - 0.47 9.8 2.1 0.69 9.3 2.1 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions EzrA PF06160.12 KPI35121.1 - 0.48 8.5 2.3 7.4 4.6 0.2 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA IF-2B PF01008.17 KPI35122.1 - 2e-26 92.9 0.0 3.4e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Lipocalin_5 PF13924.6 KPI35123.1 - 6.3e-13 48.7 0.0 6.7e-10 38.9 0.0 3.0 1 1 0 1 1 1 1 Lipocalin-like domain Epimerase PF01370.21 KPI35124.1 - 4.5e-07 29.6 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI35124.1 - 2.8e-05 24.1 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPI35124.1 - 0.00055 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Acetyltransf_9 PF13527.7 KPI35125.1 - 6.9e-08 32.6 0.0 1.5e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI35125.1 - 7.1e-05 23.2 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI35125.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI35125.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Styelin PF17562.2 KPI35125.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Styelin FR47 PF08445.10 KPI35125.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DnaJ PF00226.31 KPI35126.1 - 1e-18 67.2 0.9 1e-18 67.2 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1590 PF07629.11 KPI35126.1 - 0.058 13.2 0.6 0.19 11.6 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) Cwf_Cwc_15 PF04889.12 KPI35126.1 - 0.53 10.0 17.9 0.79 9.4 17.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 KPI35126.1 - 1.6 7.4 4.0 1.8 7.3 4.0 1.2 1 0 0 1 1 1 0 Presenilin tRNA-synt_2b PF00587.25 KPI35127.1 - 6.3e-31 107.7 0.0 3.7e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RRM_1 PF00076.22 KPI35128.1 - 1.3e-81 268.4 7.4 2.5e-21 75.3 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KPI35128.1 - 1.8e-29 101.7 0.2 8.6e-29 99.5 0.2 2.2 2 0 0 2 2 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KPI35128.1 - 4e-11 42.6 0.1 0.011 15.4 0.0 4.8 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI35128.1 - 6.5e-06 25.9 0.0 0.0041 16.9 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KPI35128.1 - 0.0003 20.9 0.3 3.3 7.9 0.0 4.8 5 1 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KPI35128.1 - 0.00038 20.4 0.3 6.8 6.8 0.0 4.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KPI35128.1 - 0.014 15.8 10.3 0.018 15.6 1.8 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT Limkain-b1 PF11608.8 KPI35128.1 - 0.016 15.3 2.7 5.2 7.2 0.1 3.6 3 0 0 3 3 3 0 Limkain b1 PhetRS_B1 PF18262.1 KPI35128.1 - 0.04 14.1 3.5 2.6 8.3 0.0 3.5 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain TC1 PF15063.6 KPI35128.1 - 0.047 13.6 0.0 9.7 6.1 0.0 2.7 2 0 0 2 2 2 0 Thyroid cancer protein 1 OB_RNB PF08206.11 KPI35128.1 - 0.063 13.0 0.9 13 5.6 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain DHHA1 PF02272.19 KPI35128.1 - 0.34 11.3 5.4 5.8 7.3 0.2 3.2 3 0 0 3 3 2 0 DHHA1 domain DNA_pol_phi PF04931.13 KPI35128.1 - 0.44 8.6 10.8 0.64 8.0 10.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 KPI35128.1 - 7.1 6.4 18.0 0.2 11.5 9.8 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2672 PF10878.8 KPI35128.1 - 7.8 6.5 6.1 1 9.3 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) Aminotran_3 PF00202.21 KPI35129.1 - 1.3e-107 360.0 0.0 2.6e-107 359.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III DUF3301 PF11743.8 KPI35129.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) IBR PF01485.21 KPI35130.1 - 5.8e-06 26.4 25.5 0.00021 21.4 6.0 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Fungal_trans_2 PF11951.8 KPI35132.1 - 4.6e-10 38.9 0.0 8.6e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATA PF00320.27 KPI35133.1 - 5.8e-30 102.6 19.2 5.3e-15 54.7 3.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KPI35133.1 - 8.7e-07 28.4 6.2 0.0015 18.0 0.5 3.0 2 1 1 3 3 3 3 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KPI35133.1 - 4.5e-05 23.5 2.2 0.15 12.2 0.2 2.7 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KPI35133.1 - 0.0013 18.6 3.1 0.15 12.0 0.2 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain ArfGap PF01412.18 KPI35133.1 - 0.0018 18.3 2.3 0.17 11.9 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TDP43_N PF18694.1 KPI35133.1 - 0.012 15.4 0.1 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 KPI35133.1 - 0.028 14.3 3.9 2.4 8.1 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KPI35133.1 - 0.036 14.2 8.3 0.23 11.7 0.5 2.6 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KPI35133.1 - 0.049 13.7 9.9 1.5 8.9 0.3 3.1 2 1 0 2 2 2 0 Double zinc ribbon OTT_1508_deam PF14441.6 KPI35133.1 - 0.13 12.3 0.2 4 7.5 0.1 2.3 2 0 0 2 2 2 0 OTT_1508-like deaminase NMD3 PF04981.13 KPI35133.1 - 0.4 10.1 1.1 3 7.2 0.1 2.1 2 0 0 2 2 2 0 NMD3 family zf-Sec23_Sec24 PF04810.15 KPI35133.1 - 0.54 10.4 7.1 0.25 11.4 0.3 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rubredoxin_2 PF18073.1 KPI35133.1 - 3.8 7.3 8.4 39 4.1 0.1 4.5 4 0 0 4 4 4 0 Rubredoxin metal binding domain Nudix_N_2 PF14803.6 KPI35133.1 - 7.5 6.6 10.8 10 6.1 1.3 3.3 2 1 0 2 2 2 0 Nudix N-terminal SprT-like PF10263.9 KPI35134.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family MDM10 PF12519.8 KPI35135.1 - 3.8e-129 431.6 15.8 1.7e-114 383.3 12.4 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Mei4 PF13971.6 KPI35136.1 - 6.2e-05 22.7 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 CBF PF03914.17 KPI35137.1 - 3.2e-48 164.0 1.4 1e-47 162.4 0.4 2.4 2 0 0 2 2 2 1 CBF/Mak21 family GlutR_dimer PF00745.20 KPI35137.1 - 3.6 8.1 6.8 0.66 10.4 0.9 2.8 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Tom22 PF04281.13 KPI35138.1 - 5.7e-44 149.3 0.3 6.9e-44 149.0 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 OTU PF02338.19 KPI35139.1 - 8.6e-10 39.2 0.0 1.7e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease LapD_MoxY_N PF16448.5 KPI35141.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain Dcc1 PF09724.9 KPI35142.1 - 7.4e-12 45.2 0.0 2.3e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DciA PF05258.12 KPI35142.1 - 0.046 14.1 0.1 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA TIM PF00121.18 KPI35144.1 - 5.4e-86 287.9 0.0 8.4e-86 287.3 0.0 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase Anp1 PF03452.14 KPI35144.1 - 3.7e-21 75.7 0.0 9.3e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 Anp1 Aa_trans PF01490.18 KPI35145.1 - 2.6e-25 89.0 30.9 5.2e-25 88.0 30.9 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Collagen PF01391.18 KPI35145.1 - 0.81 9.5 3.6 1.6 8.6 3.6 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 KPI35146.1 - 7.2e-25 87.6 31.5 1.1e-24 87.0 31.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4449 PF14613.6 KPI35148.1 - 1.4e-66 223.6 5.0 1.4e-66 223.6 5.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) PHA_gran_rgn PF09650.10 KPI35148.1 - 0.038 14.3 0.2 0.038 14.3 0.2 2.6 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Prp18 PF02840.15 KPI35148.1 - 0.048 13.7 0.1 0.048 13.7 0.1 3.4 3 1 1 4 4 4 0 Prp18 domain MIEAP PF16026.5 KPI35148.1 - 0.65 10.2 8.9 0.31 11.2 0.4 3.2 2 1 0 3 3 3 0 Mitochondria-eating protein Glyco_hydro_125 PF06824.11 KPI35149.1 - 1.7e-48 165.6 0.0 1.9e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) F-box-like_2 PF13013.6 KPI35150.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain MFS_1 PF07690.16 KPI35151.1 - 2e-35 122.4 25.7 2.9e-35 121.9 25.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2300 PF10062.9 KPI35152.1 - 0.023 14.8 0.2 0.04 14.0 0.2 1.4 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) P5CR_dimer PF14748.6 KPI35153.1 - 5.9e-28 97.1 3.3 8.4e-28 96.6 1.9 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KPI35153.1 - 2.8e-10 40.6 0.1 1.8e-09 38.0 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KPI35153.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase DUF1421 PF07223.11 KPI35153.1 - 0.21 11.4 0.8 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Nuf2 PF03800.14 KPI35154.1 - 5.1e-41 140.1 0.4 1.5e-40 138.5 0.4 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KPI35154.1 - 8.4e-33 112.9 19.6 8.4e-33 112.9 19.6 3.9 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KPI35154.1 - 1.4e-06 28.8 15.6 1.4e-06 28.8 15.6 4.2 1 1 2 4 4 4 2 Bacterial type III secretion protein (HrpB7) DUF3584 PF12128.8 KPI35154.1 - 0.00075 17.2 40.3 0.001 16.8 40.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF2935 PF11155.8 KPI35154.1 - 0.004 17.5 0.4 1.7 9.0 0.1 3.5 2 2 0 2 2 2 1 Domain of unknown function (DUF2935) CENP-H PF05837.12 KPI35154.1 - 0.0047 17.3 10.1 0.0047 17.3 10.1 4.4 2 2 2 4 4 4 1 Centromere protein H (CENP-H) Mst1_SARAH PF11629.8 KPI35154.1 - 0.0094 16.0 3.0 0.0094 16.0 3.0 4.3 3 0 0 3 3 3 1 C terminal SARAH domain of Mst1 DUF4407 PF14362.6 KPI35154.1 - 0.028 13.8 39.6 0.42 9.9 21.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KPI35154.1 - 0.13 12.8 28.7 1.4 9.5 9.7 4.9 1 1 3 4 4 4 0 Syntaxin 6, N-terminal FPP PF05911.11 KPI35154.1 - 0.14 10.3 43.0 0.68 8.1 20.9 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DASH_Hsk3 PF08227.11 KPI35154.1 - 0.25 11.8 15.3 0.31 11.5 1.1 4.4 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like BLOC1_2 PF10046.9 KPI35154.1 - 0.75 10.1 42.6 2.2 8.7 0.5 5.4 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSBP1 PF06825.12 KPI35154.1 - 1.3 9.0 8.0 0.43 10.5 0.2 3.7 3 1 0 3 3 3 0 Heat shock factor binding protein 1 STI1 PF17830.1 KPI35154.1 - 2 8.4 6.2 1.1 9.3 1.0 3.1 3 0 0 3 3 3 0 STI1 domain Spc7 PF08317.11 KPI35154.1 - 4.2 6.2 58.4 17 4.2 22.9 3.8 1 1 2 3 3 3 0 Spc7 kinetochore protein DNA_pol_D_N PF18018.1 KPI35154.1 - 6.5 6.9 9.1 4.8e+02 0.8 9.1 2.7 1 1 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain ALIX_LYPXL_bnd PF13949.6 KPI35154.1 - 7.1 5.8 46.6 3.5 6.8 23.0 2.7 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV GCV_T PF01571.21 KPI35155.1 - 0.0012 18.3 0.0 0.003 17.0 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain R3H PF01424.22 KPI35156.1 - 1.1e-08 34.9 0.0 2.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KPI35156.1 - 1.7e-08 34.2 2.0 3.6e-08 33.2 2.0 1.6 1 0 0 1 1 1 1 G-patch domain Chromo PF00385.24 KPI35156.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.7 KPI35156.1 - 0.035 14.2 3.5 0.1 12.7 1.4 2.9 2 0 0 2 2 2 0 G-patch domain RBD-FIP PF09457.10 KPI35156.1 - 0.57 10.1 2.4 1.8 8.5 2.4 1.8 1 0 0 1 1 1 0 FIP domain DUF1993 PF09351.10 KPI35157.1 - 6.1e-31 107.7 0.0 7.1e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DinB_2 PF12867.7 KPI35157.1 - 0.003 18.1 0.2 0.0045 17.5 0.2 1.2 1 0 0 1 1 1 1 DinB superfamily PS-DH PF14765.6 KPI35158.1 - 1.5e-61 208.2 0.1 2.7e-61 207.4 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KPI35158.1 - 8.4e-60 202.5 0.0 1.5e-59 201.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KPI35158.1 - 2.5e-55 187.2 0.3 7.2e-54 182.4 0.1 2.9 3 0 0 3 3 2 1 KR domain Acyl_transf_1 PF00698.21 KPI35158.1 - 2.8e-53 181.5 0.1 5.6e-53 180.5 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KPI35158.1 - 2.3e-35 121.2 0.2 5.2e-35 120.0 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KPI35158.1 - 2.7e-20 72.9 0.1 7.9e-20 71.4 0.1 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KPI35158.1 - 2.3e-16 60.4 0.0 6.4e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KPI35158.1 - 6.1e-14 52.1 0.0 3.4e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI35158.1 - 2.9e-12 47.8 0.0 1.1e-11 45.9 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KPI35158.1 - 1.2e-09 37.9 1.0 4.8e-08 32.7 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KPI35158.1 - 1.7e-08 34.4 0.0 4.9e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI35158.1 - 1.8e-07 31.7 0.0 6.7e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI35158.1 - 2.2e-07 31.5 0.0 1.1e-06 29.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI35158.1 - 3.2e-07 30.3 0.0 9.1e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KPI35158.1 - 1.7e-05 24.6 0.2 4.2e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KPI35158.1 - 3.6e-05 23.4 0.7 9.5e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KPI35158.1 - 0.0021 18.4 0.1 0.0071 16.7 0.1 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site DUF938 PF06080.12 KPI35158.1 - 0.0098 15.7 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_28 PF02636.17 KPI35158.1 - 0.096 12.3 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyl_transf_3 PF01757.22 KPI35159.1 - 6.9e-20 71.4 22.7 3.2e-18 65.9 22.7 2.2 1 1 0 1 1 1 1 Acyltransferase family DUF1978 PF09321.10 KPI35160.1 - 0.12 11.6 3.8 0.25 10.6 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) ABC_tran_Xtn PF12848.7 KPI35160.1 - 0.37 10.8 3.5 8.9 6.4 0.6 2.5 2 0 0 2 2 2 0 ABC transporter ECH_1 PF00378.20 KPI35161.1 - 1.5e-33 116.2 0.1 2.9e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI35161.1 - 5.6e-18 65.5 0.6 1.4e-17 64.2 0.1 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase MRG PF05712.13 KPI35162.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 MRG zf-TFIIB PF13453.6 KPI35162.1 - 0.098 12.0 3.5 6 6.3 0.2 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Shikimate_dh_N PF08501.11 KPI35163.1 - 7.7e-21 74.2 0.0 1.9e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KPI35163.1 - 0.00014 21.5 0.1 0.00032 20.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KPI35163.1 - 0.00084 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI35163.1 - 0.0086 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Beta-lactamase PF00144.24 KPI35164.1 - 7.1e-39 134.0 0.0 1.1e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase zf-C3Hc3H PF13891.6 KPI35164.1 - 0.057 13.8 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Potential DNA-binding domain HATPase_c_3 PF13589.6 KPI35165.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-oxoacid_dh PF00198.23 KPI35166.1 - 2.1e-80 269.5 0.1 2.9e-80 269.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPI35166.1 - 2.1e-19 69.1 2.2 4e-19 68.2 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KPI35166.1 - 3.2e-06 26.9 0.2 4.6e-05 23.1 0.1 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KPI35166.1 - 0.0002 22.0 0.3 0.027 15.2 0.1 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 KPI35166.1 - 0.0058 16.6 2.3 0.92 9.5 0.0 2.9 2 1 1 3 3 3 2 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 KPI35166.1 - 0.019 14.8 0.2 0.039 13.8 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 KPI35166.1 - 0.019 14.2 0.2 0.074 12.3 0.1 1.9 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3614 PF12267.8 KPI35166.1 - 0.058 13.9 0.1 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) DUF2457 PF10446.9 KPI35166.1 - 0.22 10.6 14.2 0.35 10.0 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 KPI35166.1 - 2.5 6.8 3.8 3.6 6.2 3.8 1.3 1 0 0 1 1 1 0 Presenilin DAO PF01266.24 KPI35167.1 - 1.8e-38 133.0 0.0 2.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI35167.1 - 3.3e-06 26.6 0.0 4.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI35167.1 - 6.2e-06 25.5 0.3 0.0005 19.3 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KPI35167.1 - 6.9e-06 26.2 0.1 1.6e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI35167.1 - 0.00011 21.5 0.0 0.06 12.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI35167.1 - 0.00019 20.8 0.0 0.0029 16.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI35167.1 - 0.00055 18.7 0.0 0.19 10.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KPI35167.1 - 0.0017 18.3 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 KPI35167.1 - 0.0032 17.0 0.0 0.057 12.9 0.0 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ThiF PF00899.21 KPI35167.1 - 0.0048 16.3 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family PSI_PsaE PF02427.17 KPI35167.1 - 0.07 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE Shikimate_DH PF01488.20 KPI35167.1 - 0.071 13.2 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KPI35167.1 - 0.092 13.3 0.0 3.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI35167.1 - 0.097 11.7 0.0 9.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KPI35167.1 - 0.12 11.8 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.16 KPI35167.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KPI35167.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KPI35167.1 - 0.22 11.0 0.0 0.59 9.7 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MBOAT_2 PF13813.6 KPI35168.1 - 3.8e-13 49.5 7.5 1.8e-12 47.3 7.5 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Bys1 PF04681.12 KPI35169.1 - 0.0036 17.2 0.2 0.0073 16.2 0.2 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Iso_dh PF00180.20 KPI35170.1 - 1.1e-105 353.6 0.0 1.3e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AMP-binding PF00501.28 KPI35171.1 - 7.4e-85 285.1 0.0 9.4e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI35171.1 - 1.1e-14 55.2 0.5 2.1e-14 54.3 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain T5orf172 PF10544.9 KPI35172.1 - 1.5e-16 60.8 0.0 4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KPI35172.1 - 1.2e-15 57.9 0.2 3.6e-15 56.4 0.2 1.9 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Fungal_trans_2 PF11951.8 KPI35173.1 - 1.1e-25 90.2 0.0 4.6e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35173.1 - 0.00036 20.6 6.6 0.00071 19.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KPI35174.1 - 5.5e-13 49.5 9.8 1.3e-10 41.8 1.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.23 KPI35174.1 - 8.8e-06 25.8 0.0 3.7e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI35174.1 - 6.9e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KPI35174.1 - 0.32 11.0 1.2 4.2 7.4 0.1 2.7 2 1 0 3 3 3 0 Dynamin family DUF87 PF01935.17 KPI35174.1 - 0.36 10.9 0.8 0.75 9.8 0.8 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain adh_short_C2 PF13561.6 KPI35176.1 - 1.4e-59 201.5 1.9 1.6e-59 201.3 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35176.1 - 1.6e-47 161.5 1.0 1.9e-47 161.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35176.1 - 1.6e-11 44.4 0.8 2.4e-11 43.9 0.6 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPI35176.1 - 0.004 17.0 0.3 0.0066 16.4 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3425 PF11905.8 KPI35177.1 - 6.7e-21 74.5 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Histone PF00125.24 KPI35178.1 - 2.2e-21 76.6 0.6 2.8e-21 76.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KPI35178.1 - 7.2e-05 23.0 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KPI35178.1 - 0.00039 20.8 0.0 0.00069 20.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KPI35178.1 - 0.069 12.8 0.3 0.26 10.9 0.1 2.0 2 1 0 2 2 2 0 Replication protein C N-terminal domain DUF1018 PF06252.12 KPI35178.1 - 0.083 13.9 2.2 0.12 13.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Gpi1 PF05024.15 KPI35179.1 - 6.5e-76 254.6 10.1 1.3e-75 253.6 10.1 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF2628 PF10947.8 KPI35179.1 - 0.55 10.6 3.7 2.2 8.7 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) CpXC PF14353.6 KPI35180.1 - 0.053 13.6 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 CpXC protein DNA_RNApol_7kD PF03604.13 KPI35180.1 - 0.11 12.2 1.5 0.9 9.3 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FUR PF01475.19 KPI35180.1 - 0.18 11.9 1.3 0.42 10.8 0.1 1.8 1 1 1 2 2 2 0 Ferric uptake regulator family SR1P PF13790.6 KPI35180.1 - 0.27 11.4 3.0 4.3 7.5 0.4 2.3 1 1 1 2 2 2 0 SR1 protein Rubredoxin_2 PF18073.1 KPI35180.1 - 0.71 9.6 5.6 8 6.3 5.6 2.1 1 1 0 1 1 1 0 Rubredoxin metal binding domain Mannosyl_trans3 PF11051.8 KPI35181.1 - 2.2e-34 119.1 0.0 9.9e-25 87.4 0.0 2.3 1 1 1 2 2 2 2 Mannosyltransferase putative FAD_binding_3 PF01494.19 KPI35182.1 - 1.8e-09 37.3 0.0 0.0006 19.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI35182.1 - 0.00013 21.7 0.2 0.00032 20.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI35182.1 - 0.00018 21.7 0.0 0.00051 20.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI35182.1 - 0.00042 19.6 0.0 0.0013 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI35182.1 - 0.0069 15.3 0.1 0.019 13.8 0.1 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KPI35182.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Histone_H2A_C PF16211.5 KPI35183.1 - 2.4e-21 75.1 2.9 4.4e-21 74.3 2.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KPI35183.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KPI35183.1 - 9.9e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ApbA_C PF08546.11 KPI35184.1 - 1.3e-29 102.9 0.0 2.3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPI35184.1 - 1.9e-28 99.0 0.0 2.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RNA_ligase PF09414.10 KPI35185.1 - 8.3e-10 39.2 0.0 1.5e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 RNA ligase Fungal_trans_2 PF11951.8 KPI35187.1 - 1.1e-11 44.2 0.1 1.8e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Helicase_C_2 PF13307.6 KPI35188.1 - 8.8e-56 188.7 0.1 3.3e-55 186.9 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KPI35188.1 - 2.4e-50 170.6 0.1 4.4e-50 169.7 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KPI35188.1 - 0.00018 21.2 0.2 0.00081 19.1 0.0 2.1 3 0 0 3 3 3 1 Helical and beta-bridge domain ResIII PF04851.15 KPI35188.1 - 0.003 17.6 0.0 4.3 7.3 0.0 2.7 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI35188.1 - 0.0059 16.4 0.1 2.7 7.7 0.0 2.5 2 1 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 KPI35188.1 - 0.02 14.4 0.3 5.3 6.4 0.0 3.0 2 1 1 3 3 3 0 PhoH-like protein Rogdi_lz PF10259.9 KPI35188.1 - 0.088 12.2 0.3 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein AAA_22 PF13401.6 KPI35188.1 - 0.12 12.7 0.3 3.2 8.0 0.2 2.9 2 1 0 2 2 2 0 AAA domain DUF4192 PF13830.6 KPI35188.1 - 0.4 10.7 4.5 0.61 10.1 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Syntaxin PF00804.25 KPI35188.1 - 2.3 7.8 8.1 5.7 6.6 0.9 2.4 2 0 0 2 2 2 0 Syntaxin Chromate_transp PF02417.15 KPI35189.1 - 9.7e-57 191.5 35.2 3.4e-34 118.2 12.4 2.6 3 0 0 3 3 3 2 Chromate transporter RTA1 PF04479.13 KPI35191.1 - 1.2e-64 217.8 8.1 1.2e-64 217.8 8.1 1.4 2 0 0 2 2 2 1 RTA1 like protein AA_permease_2 PF13520.6 KPI35192.1 - 9.1e-56 189.5 62.0 1.2e-55 189.1 62.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI35192.1 - 1.6e-22 79.8 51.5 2.2e-22 79.3 51.5 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KPI35193.1 - 5.1e-100 335.5 24.6 5.8e-100 335.3 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35193.1 - 1.1e-30 106.8 55.5 4.4e-28 98.2 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI35193.1 - 0.00057 18.4 2.2 0.00087 17.8 1.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4044 PF13253.6 KPI35193.1 - 0.57 9.7 2.2 11 5.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Pyr_redox_3 PF13738.6 KPI35195.1 - 5.1e-15 55.5 0.0 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI35195.1 - 4.3e-13 49.1 0.0 1.2e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI35195.1 - 1.8e-11 43.2 0.0 8.2e-11 41.0 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI35195.1 - 3.7e-07 30.3 0.0 8.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI35195.1 - 2.5e-05 23.6 0.0 0.00013 21.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPI35195.1 - 0.00047 19.8 0.2 3.2 7.2 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KPI35195.1 - 0.031 14.7 0.0 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KPI35195.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KPI35195.1 - 0.038 13.1 0.2 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KPI35195.1 - 0.069 11.8 0.3 0.96 8.1 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KPI35195.1 - 0.09 12.0 0.7 0.45 9.7 0.1 2.3 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 KPI35195.1 - 0.13 12.3 5.2 11 6.0 1.0 3.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding Methyltransf_25 PF13649.6 KPI35196.1 - 6e-15 55.7 0.0 1.2e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI35196.1 - 1.3e-12 48.3 0.1 3.3e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI35196.1 - 5.6e-11 43.0 0.1 2.1e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI35196.1 - 1.6e-06 28.0 0.0 2.8e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI35196.1 - 7.5e-06 25.9 0.0 1.3e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI35196.1 - 9.8e-06 25.1 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPI35196.1 - 2.9e-05 23.7 0.0 5.4e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KPI35196.1 - 3.7e-05 23.4 0.0 5.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Cons_hypoth95 PF03602.15 KPI35196.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 KPI35196.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KPI35196.1 - 0.07 14.2 0.3 0.17 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain NUDIX PF00293.28 KPI35197.1 - 2.9e-14 53.2 0.2 5.5e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KPI35197.1 - 1.4e-08 35.3 0.0 3.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KPI35197.1 - 4.5e-07 29.4 2.8 9.6e-07 28.4 2.8 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.24 KPI35198.1 - 1.3e-130 436.3 30.2 1.6e-130 436.0 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35198.1 - 9.2e-20 70.8 45.3 7.4e-19 67.9 38.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH_C PF18031.1 KPI35200.1 - 0.4 10.6 2.7 0.62 10.0 2.7 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Man-6-P_recep PF02157.15 KPI35202.1 - 1.2e-15 57.3 0.0 2e-15 56.6 0.0 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KPI35202.1 - 2.4e-12 47.3 0.0 4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 BAR_2 PF10455.9 KPI35202.1 - 0.0042 16.3 0.1 0.0059 15.8 0.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking CIMR PF00878.18 KPI35202.1 - 0.0099 16.0 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat RNA_GG_bind PF10258.9 KPI35202.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain Complex1_LYR PF05347.15 KPI35203.1 - 5e-09 36.1 1.4 6.9e-09 35.6 1.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Fungal_trans PF04082.18 KPI35204.1 - 4.2e-23 81.7 0.0 7.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35204.1 - 1.7e-09 37.7 10.2 2.7e-09 37.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase_3 PF13468.6 KPI35205.1 - 0.00032 20.8 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Peptidase_M91 PF14891.6 KPI35205.1 - 0.012 16.0 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Effector protein adh_short_C2 PF13561.6 KPI35206.1 - 1.8e-35 122.6 0.0 2.1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35206.1 - 1.4e-17 63.8 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35206.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 KR domain Sel1 PF08238.12 KPI35207.1 - 1.3e-23 82.9 21.1 4e-08 33.7 0.4 7.0 7 0 0 7 7 7 6 Sel1 repeat TPR_2 PF07719.17 KPI35207.1 - 3.4 8.0 8.0 1.2 9.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI35207.1 - 5.2 7.1 7.6 1.2 9.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat A_deamin PF02137.18 KPI35208.1 - 2.2e-15 57.0 0.0 3.7e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF3328 PF11807.8 KPI35209.1 - 6.6e-55 186.3 0.4 8.4e-55 185.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UCR_Fe-S_N PF10399.9 KPI35210.1 - 3.5 7.0 8.6 0.26 10.7 3.1 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Aldedh PF00171.22 KPI35211.1 - 6.9e-69 232.5 0.0 1.9e-63 214.6 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Peptidase_C54 PF03416.19 KPI35213.1 - 3.7e-96 321.8 0.0 4.6e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 ERG4_ERG24 PF01222.17 KPI35214.1 - 8.5e-121 403.7 2.5 1.1e-98 330.8 0.1 2.0 2 0 0 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family FixQ PF05545.11 KPI35214.1 - 0.35 10.9 0.0 0.35 10.9 0.0 4.0 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ Aldedh PF00171.22 KPI35216.1 - 4.4e-152 506.8 0.0 5e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_16 PF13432.6 KPI35216.1 - 0.018 15.7 0.4 4.1 8.1 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CLU PF13236.6 KPI35217.1 - 1.3e-65 221.3 0.1 1e-53 182.4 0.0 2.5 1 1 1 2 2 2 2 Clustered mitochondria eIF3_p135 PF12807.7 KPI35217.1 - 7e-52 176.0 2.2 8.8e-52 175.7 0.0 2.3 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KPI35217.1 - 2e-26 92.0 4.2 2.7e-12 46.8 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 KPI35217.1 - 1e-25 89.8 1.0 3.1e-25 88.4 1.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KPI35217.1 - 3.8e-24 83.8 0.2 1.8e-05 24.4 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35217.1 - 6e-06 26.0 0.7 9.1 6.7 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 KPI35217.1 - 6.6e-05 22.9 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 KPI35217.1 - 0.00022 21.2 2.5 0.3 11.4 0.2 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ubiquitin PF00240.23 KPI35217.1 - 0.0072 16.1 0.4 0.016 15.0 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 KPI35217.1 - 0.03 14.5 0.9 0.31 11.3 0.1 2.6 2 0 0 2 2 2 0 UBX domain adh_short_C2 PF13561.6 KPI35218.1 - 9.5e-61 205.3 0.7 1.2e-60 205.1 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35218.1 - 1.8e-54 184.2 1.2 2.3e-54 183.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35218.1 - 1.4e-05 25.1 0.6 2.3e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI35218.1 - 0.013 15.0 0.2 0.028 13.9 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_16 PF13191.6 KPI35220.1 - 3.1e-06 27.7 0.0 9.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KPI35220.1 - 0.024 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KPI35220.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KPI35220.1 - 0.032 14.0 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KPI35220.1 - 0.042 13.2 0.3 0.096 12.0 0.1 1.6 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 KPI35220.1 - 0.054 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 KPI35220.1 - 0.1 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KPI35220.1 - 0.12 12.6 0.2 0.35 11.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain GFO_IDH_MocA PF01408.22 KPI35221.1 - 4.3e-25 88.9 0.2 5.9e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI35221.1 - 3.4e-14 52.9 0.0 6.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 KPI35221.1 - 0.0069 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain Semialdhyde_dh PF01118.24 KPI35221.1 - 0.038 14.4 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPI35221.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KPI35221.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AP_endonuc_2 PF01261.24 KPI35222.1 - 5.2e-29 101.2 0.0 5.1e-28 98.0 0.0 1.9 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel PIG-P PF08510.12 KPI35223.1 - 4.9e-48 162.0 0.5 2e-47 160.0 0.5 1.9 1 1 0 1 1 1 1 PIG-P Med19 PF10278.9 KPI35223.1 - 0.5 10.3 4.6 0.87 9.5 4.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DPM2 PF07297.12 KPI35223.1 - 1.3 9.3 8.2 2.2 8.7 8.2 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF3405 PF11885.8 KPI35225.1 - 1.2e-156 522.4 2.6 4.2e-91 306.1 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) MFS_1 PF07690.16 KPI35225.1 - 0.2 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily zf-C2H2_jaz PF12171.8 KPI35226.1 - 2.6e-06 27.6 3.6 2.6e-06 27.6 3.6 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI35226.1 - 0.0053 17.1 0.7 0.009 16.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Tup_N PF08581.10 KPI35226.1 - 0.094 13.0 1.0 0.094 13.0 1.0 1.6 2 0 0 2 2 2 0 Tup N-terminal zf-DBF PF07535.12 KPI35226.1 - 0.14 12.2 2.8 0.25 11.5 2.8 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.26 KPI35226.1 - 0.2 12.2 0.7 0.2 12.2 0.7 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Img2 PF05046.14 KPI35228.1 - 9.5e-24 83.5 0.0 1.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF4519 PF15012.6 KPI35228.1 - 0.18 12.0 2.2 13 6.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 2OG-FeII_Oxy PF03171.20 KPI35229.1 - 7.4e-17 61.7 0.0 2.1e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPI35229.1 - 8.3e-14 52.4 0.0 1.4e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CysA_C_terminal PF17850.1 KPI35229.1 - 0.072 13.7 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 CysA C-terminal regulatory domain Sec23_trunk PF04811.15 KPI35230.1 - 2.6e-71 240.0 0.0 3.9e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KPI35230.1 - 1e-23 83.1 0.0 3.3e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KPI35230.1 - 3.1e-17 63.1 0.0 7.9e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KPI35230.1 - 2.7e-16 59.3 3.7 4.6e-16 58.6 3.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KPI35230.1 - 3.2e-10 39.8 0.0 9.4e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KPI35230.1 - 0.0059 16.0 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain GPDPase_memb PF10110.9 KPI35231.1 - 0.0087 14.9 3.6 0.012 14.4 3.6 1.1 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase DHHC PF01529.20 KPI35231.1 - 0.034 14.3 6.2 0.052 13.7 6.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3093 PF11292.8 KPI35231.1 - 0.054 13.8 3.1 9.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) RDD PF06271.12 KPI35231.1 - 0.33 11.1 6.5 0.65 10.2 6.5 1.5 1 0 0 1 1 1 0 RDD family PIG-P PF08510.12 KPI35231.1 - 2.7 7.9 11.1 0.82 9.6 0.5 2.4 1 1 1 2 2 2 0 PIG-P Amidohydro_1 PF01979.20 KPI35232.1 - 9.1e-24 84.4 0.0 3e-13 49.8 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KPI35232.1 - 4.5e-11 42.9 0.1 2.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family NPCC PF08058.11 KPI35234.1 - 1.2e-19 70.6 0.1 2.4e-19 69.7 0.0 1.5 2 0 0 2 2 2 1 Nuclear pore complex component FAD_binding_4 PF01565.23 KPI35235.1 - 4.1e-22 78.4 1.5 7e-22 77.7 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain Peptidase_S15 PF02129.18 KPI35236.1 - 7.4e-42 143.8 0.1 6.2e-40 137.5 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KPI35236.1 - 1.7e-21 77.2 0.0 2.5e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF2272 PF10030.9 KPI35237.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) Big_7 PF17957.1 KPI35237.1 - 0.16 12.8 2.0 11 6.8 0.5 2.7 3 0 0 3 3 3 0 Bacterial Ig domain Cupin_2 PF07883.11 KPI35238.1 - 5.6e-06 26.0 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPI35238.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MOSC PF03473.17 KPI35239.1 - 6.3e-25 87.7 0.0 9e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPI35239.1 - 4.7e-09 36.2 0.0 7.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Pkinase PF00069.25 KPI35240.1 - 4.2e-68 229.6 0.0 5e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI35240.1 - 6.8e-32 110.8 0.0 9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPI35240.1 - 0.00027 20.4 0.3 0.00045 19.6 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPI35240.1 - 0.0024 16.9 0.1 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KPI35240.1 - 0.011 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KPI35240.1 - 0.037 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KPI35240.1 - 0.055 12.5 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_transf_24 PF18404.1 KPI35241.1 - 3.2e-149 495.7 1.6 5.5e-149 494.9 1.6 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KPI35241.1 - 2.4e-54 185.0 0.0 4.6e-54 184.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KPI35241.1 - 2.1e-45 155.0 0.0 3.7e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KPI35241.1 - 1.5e-41 140.9 0.0 3.2e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KPI35241.1 - 2.3e-38 131.2 0.5 6.4e-38 129.7 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KPI35241.1 - 1.4e-28 100.3 0.1 6.2e-19 68.8 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KPI35241.1 - 0.00016 21.3 0.1 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.12 KPI35241.1 - 0.047 13.6 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) BCS1_N PF08740.11 KPI35242.1 - 5.5e-34 117.8 2.5 1e-33 116.9 2.5 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPI35242.1 - 1.1e-15 58.3 0.0 3.4e-07 30.7 0.0 2.7 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPI35242.1 - 0.048 13.4 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NmrA PF05368.13 KPI35243.1 - 7e-59 199.2 0.0 1.1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Asparaginase PF00710.20 KPI35243.1 - 2.2e-58 197.0 0.0 3.4e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KPI35243.1 - 6.5e-16 58.6 0.1 7.8e-15 55.1 0.1 2.3 1 1 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain NAD_binding_10 PF13460.6 KPI35243.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TRI12 PF06609.13 KPI35244.1 - 7e-22 77.6 25.9 1e-21 77.0 25.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI35244.1 - 2.5e-21 76.0 49.4 2.5e-21 76.0 49.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Glug PF07581.12 KPI35244.1 - 2 9.0 7.5 11 6.6 7.5 2.4 1 0 0 1 1 1 0 The GLUG motif ECH_1 PF00378.20 KPI35245.1 - 3.6e-21 75.6 0.0 7.7e-19 68.0 0.0 2.5 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI35245.1 - 8.4e-07 28.8 0.0 0.00045 19.8 0.0 2.5 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4690 PF15756.5 KPI35247.1 - 0.014 15.9 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 KPI35247.1 - 0.022 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Podoplanin DAP10 PF07213.11 KPI35247.1 - 0.033 14.2 0.5 0.2 11.7 0.2 2.4 3 0 0 3 3 3 0 DAP10 membrane protein VSP PF03302.13 KPI35247.1 - 0.041 12.7 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein CYYR1 PF10873.8 KPI35247.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 LapA_dom PF06305.11 KPI35247.1 - 0.21 11.4 1.8 0.42 10.4 1.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3042 PF11240.8 KPI35247.1 - 1.5 8.9 3.8 2.8 8.0 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Cnn_1N PF07989.11 KPI35248.1 - 2e-23 82.3 4.3 2e-23 82.3 4.3 15.6 6 4 7 15 15 15 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KPI35248.1 - 6.1e-15 55.6 1.3 6.1e-15 55.6 1.3 5.9 6 1 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.15 KPI35248.1 - 0.005 17.3 187.4 0.014 15.8 23.2 9.1 1 1 8 9 9 9 4 Fez1 WD40_alt PF14077.6 KPI35248.1 - 0.092 12.6 8.4 9 6.3 1.0 5.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif SlyX PF04102.12 KPI35248.1 - 0.34 11.6 0.1 0.34 11.6 0.1 17.3 8 7 9 18 18 18 0 SlyX Spc7 PF08317.11 KPI35248.1 - 9.9 4.9 206.9 0.023 13.6 9.7 9.7 2 2 8 10 10 10 0 Spc7 kinetochore protein APH PF01636.23 KPI35249.1 - 0.014 15.4 0.1 0.075 12.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family LETM1 PF07766.13 KPI35251.1 - 0.017 14.5 0.1 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 LETM1-like protein Fst_toxin PF13955.6 KPI35252.1 - 0.058 13.3 0.1 0.058 13.3 0.1 2.0 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system TPR_2 PF07719.17 KPI35253.1 - 2.7e-08 33.3 25.6 0.0017 18.3 0.2 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPI35253.1 - 7.5e-05 23.0 14.5 0.023 15.0 1.7 5.9 4 2 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KPI35253.1 - 0.00019 21.8 8.0 0.13 13.0 0.8 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPI35253.1 - 0.00028 21.5 19.5 8.3 7.5 0.5 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPI35253.1 - 0.00031 20.3 24.3 0.0059 16.3 0.2 6.3 6 1 1 7 7 7 3 TPR repeat TPR_7 PF13176.6 KPI35253.1 - 0.00044 20.1 13.9 2 8.6 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI35253.1 - 0.0022 18.0 21.2 0.24 11.7 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI35253.1 - 0.005 17.5 24.3 2.5 8.8 0.5 6.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPI35253.1 - 0.0078 16.0 20.9 0.68 9.9 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPI35253.1 - 0.035 14.5 4.5 4.9 7.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPI35253.1 - 0.044 14.3 17.2 2.4 8.7 0.1 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KPI35253.1 - 0.17 11.2 1.0 0.59 9.4 1.0 1.9 1 1 0 1 1 1 0 MalT-like TPR region CHRD PF07452.12 KPI35254.1 - 1.7e-12 48.3 0.1 2.1e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 CHRD domain MFS_1 PF07690.16 KPI35256.1 - 3.1e-26 92.2 42.7 6e-14 51.7 15.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35256.1 - 0.0023 16.9 0.1 0.0023 16.9 0.1 3.5 3 1 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_67M PF07488.12 KPI35259.1 - 7.5e-136 452.5 0.1 1.1e-135 451.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KPI35259.1 - 4.2e-83 278.3 0.4 6.1e-83 277.7 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KPI35259.1 - 3.5e-28 98.3 0.0 6.5e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KPI35259.1 - 0.008 17.0 0.1 0.019 15.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Fungal_trans PF04082.18 KPI35261.1 - 3.4e-14 52.5 0.0 6.3e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35261.1 - 1e-09 38.3 7.1 2.5e-09 37.1 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KPI35262.1 - 4.2e-36 124.9 0.2 4.3e-35 121.6 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI35262.1 - 0.00094 18.5 0.1 0.0015 17.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TRI12 PF06609.13 KPI35263.1 - 8.6e-17 60.8 19.7 3.1e-14 52.3 11.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI35263.1 - 1.1e-10 41.0 66.9 2.8e-09 36.4 21.4 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Fanconi_A PF03511.14 KPI35263.1 - 0.012 15.5 0.3 5.4 7.0 0.1 2.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein DUF1772 PF08592.11 KPI35265.1 - 6.2e-23 81.6 1.3 6.8e-23 81.5 0.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) SlyX PF04102.12 KPI35266.1 - 0.0023 18.5 2.9 0.018 15.6 0.3 2.5 2 0 0 2 2 2 1 SlyX SMODS PF18144.1 KPI35266.1 - 0.02 15.0 0.6 0.035 14.3 0.4 1.5 1 1 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain FlaC_arch PF05377.11 KPI35266.1 - 0.039 14.3 1.6 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KPI35266.1 - 0.06 13.5 2.7 0.33 11.2 0.7 2.3 1 1 1 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 KPI35266.1 - 0.067 13.7 2.2 0.1 13.1 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 KPI35266.1 - 0.068 13.2 4.3 0.11 12.6 4.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SHE3 PF17078.5 KPI35266.1 - 0.091 12.5 2.1 0.13 12.0 2.1 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Hfq PF17209.3 KPI35266.1 - 0.092 12.4 0.2 0.29 10.8 0.1 1.8 2 0 0 2 2 2 0 Hfq protein UPF0242 PF06785.11 KPI35266.1 - 0.093 12.8 1.7 0.14 12.2 1.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 KPI35266.1 - 0.12 13.0 4.2 0.2 12.3 4.2 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KPI35266.1 - 0.14 11.0 3.0 0.19 10.6 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 KPI35266.1 - 0.15 11.3 5.5 0.27 10.5 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 KPI35266.1 - 0.19 11.7 2.4 1.7 8.6 2.4 2.1 1 1 0 1 1 1 0 Prefoldin subunit CENP-H PF05837.12 KPI35266.1 - 0.27 11.7 3.5 0.48 10.9 3.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SOAR PF16533.5 KPI35266.1 - 0.31 11.0 2.8 0.62 10.1 2.8 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region Fib_alpha PF08702.10 KPI35266.1 - 0.47 10.6 3.9 0.31 11.2 2.2 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 KPI35266.1 - 0.47 10.6 3.4 2.6 8.2 0.4 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.12 KPI35266.1 - 0.6 10.1 4.4 0.55 10.3 3.5 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 KPI35266.1 - 0.73 10.5 3.5 3.2 8.4 3.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Csm1_N PF18504.1 KPI35266.1 - 0.87 10.0 4.4 5.7 7.4 0.7 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain HisKA_3 PF07730.13 KPI35266.1 - 0.99 10.0 4.4 1.1 9.8 0.8 2.4 2 1 1 3 3 2 0 Histidine kinase TolA_bind_tri PF16331.5 KPI35266.1 - 1.2 9.3 6.6 1 9.5 0.5 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation Cluap1 PF10234.9 KPI35266.1 - 2.3 7.5 5.9 2.9 7.2 5.6 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF1100 PF06500.11 KPI35267.1 - 6.7e-15 54.8 0.0 8.4e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KPI35267.1 - 6.6e-09 36.7 1.5 1.8e-08 35.3 0.5 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI35267.1 - 2.2e-07 30.8 0.0 8.5e-06 25.6 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPI35267.1 - 4.4e-07 29.8 0.0 6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KPI35267.1 - 8.6e-06 25.6 0.0 0.00011 22.0 0.0 2.3 2 1 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KPI35267.1 - 1.7e-05 24.4 0.2 5.1e-05 22.8 0.1 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KPI35267.1 - 0.00047 20.1 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KPI35267.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KPI35267.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KPI35267.1 - 0.01 15.3 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 KPI35267.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPI35267.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S58 PF03576.14 KPI35267.1 - 0.092 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S58 AXE1 PF05448.12 KPI35267.1 - 0.12 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Fez1 PF06818.15 KPI35269.1 - 0.057 13.9 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 Fez1 DivIC PF04977.15 KPI35269.1 - 0.063 13.1 0.3 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Lactamase_B PF00753.27 KPI35270.1 - 1.2e-19 71.1 3.1 1.6e-19 70.7 3.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI35270.1 - 0.00014 21.5 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 KPI35270.1 - 0.093 11.8 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Amidohydro_1 PF01979.20 KPI35271.1 - 3.7e-24 85.7 0.0 8.6e-24 84.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI35271.1 - 4.1e-10 39.7 0.3 0.00048 19.7 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family DUF4619 PF15398.6 KPI35271.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) SURF6 PF04935.12 KPI35272.1 - 7.8e-47 159.7 33.8 7.8e-47 159.7 33.8 3.3 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KPI35272.1 - 3.5e-17 62.7 1.2 3.5e-17 62.7 1.2 8.1 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 NMO PF03060.15 KPI35273.1 - 8e-50 170.1 2.0 1.8e-48 165.7 2.0 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI35273.1 - 1.9e-12 46.9 0.4 6.2e-11 41.9 0.4 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPI35273.1 - 4.4e-05 22.7 0.2 7.3e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPI35273.1 - 0.019 14.1 0.8 0.05 12.7 0.8 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 KPI35273.1 - 0.019 14.4 0.4 0.082 12.3 0.1 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF1902 PF08972.11 KPI35273.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Asp PF00026.23 KPI35274.1 - 1.9e-61 208.2 2.7 5.5e-33 114.7 0.2 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI35274.1 - 7.2e-10 39.4 5.5 1.6e-08 35.0 0.8 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI35274.1 - 0.00079 20.0 1.9 0.069 13.8 0.2 3.1 3 0 0 3 3 3 1 Aspartyl protease SGT1 PF07093.11 KPI35275.1 - 2.9e-83 280.3 19.9 3.1e-79 267.0 0.1 2.0 2 0 0 2 2 2 2 SGT1 protein UPF0231 PF06062.11 KPI35275.1 - 0.51 10.6 4.6 16 5.8 1.0 3.2 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0231) Haspin_kinase PF12330.8 KPI35276.1 - 0.17 10.8 0.0 0.33 9.8 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain GMC_oxred_N PF00732.19 KPI35277.1 - 7.7e-58 196.2 0.0 7.1e-42 143.8 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI35277.1 - 1.1e-34 120.0 0.0 2.3e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KPI35277.1 - 0.0014 18.3 0.4 0.022 14.3 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI35277.1 - 0.0021 18.3 0.1 0.0054 16.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI35277.1 - 0.0031 16.6 0.4 0.0059 15.7 0.4 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI35277.1 - 0.0036 16.4 0.0 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KPI35277.1 - 0.0086 15.3 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KPI35277.1 - 0.054 12.7 0.7 3 7.0 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KPI35277.1 - 0.17 12.2 0.0 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Vma12 PF11712.8 KPI35278.1 - 2.4e-36 124.8 0.0 3.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MHYT PF03707.16 KPI35278.1 - 0.2 11.8 3.1 0.33 11.2 2.1 1.9 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat Metal_resist PF13801.6 KPI35278.1 - 2.5 8.3 6.5 16 5.7 0.1 3.4 4 0 0 4 4 4 0 Heavy-metal resistance Clr5 PF14420.6 KPI35279.1 - 3.6e-19 68.7 0.8 9.4e-19 67.4 0.8 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KPI35279.1 - 0.0001 22.5 2.9 0.033 14.5 0.2 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35279.1 - 0.00011 22.0 0.7 2.2 8.6 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ST7 PF04184.12 KPI35279.1 - 0.021 13.3 0.2 0.03 12.8 0.2 1.1 1 0 0 1 1 1 0 ST7 protein TPR_1 PF00515.28 KPI35279.1 - 0.022 14.6 0.1 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_33 PF13592.6 KPI35279.1 - 0.047 13.3 1.2 0.13 11.9 0.1 2.4 3 0 0 3 3 3 0 Winged helix-turn helix TPR_19 PF14559.6 KPI35279.1 - 0.058 13.9 0.8 0.58 10.7 0.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPI35279.1 - 0.13 12.3 0.3 0.99 9.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI35279.1 - 0.16 12.9 0.8 8.1 7.6 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPI35279.1 - 0.22 12.2 1.5 20 5.9 0.3 3.9 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF1996 PF09362.10 KPI35280.1 - 6.7e-78 261.9 0.3 1.1e-77 261.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RtcB PF01139.17 KPI35281.1 - 0.02 14.1 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB RTA1 PF04479.13 KPI35282.1 - 6.5e-53 179.4 4.0 1.3e-49 168.6 3.3 2.2 1 1 1 2 2 2 2 RTA1 like protein GntP_permease PF02447.16 KPI35282.1 - 0.0072 15.1 0.4 0.011 14.5 0.4 1.3 1 0 0 1 1 1 1 GntP family permease FixP_N PF14715.6 KPI35282.1 - 8.5 6.2 7.6 0.43 10.4 0.6 2.4 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP p450 PF00067.22 KPI35283.1 - 5.5e-68 229.8 0.0 6.8e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF3_N PF09440.10 KPI35284.1 - 7.7e-39 133.2 0.6 7.7e-39 133.2 0.6 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KPI35284.1 - 1.6e-13 51.1 0.0 4.2e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain DUF148 PF02520.17 KPI35284.1 - 0.41 10.8 4.2 2.3 8.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 EzrA PF06160.12 KPI35284.1 - 2.2 6.4 8.2 0.064 11.4 0.6 2.1 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Xan_ur_permease PF00860.20 KPI35286.1 - 5.5e-65 219.6 36.0 1.5e-63 214.8 36.0 2.0 1 1 0 1 1 1 1 Permease family p450 PF00067.22 KPI35287.1 - 5.1e-62 210.1 0.0 6e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoA_transf_3 PF02515.17 KPI35288.1 - 5e-38 131.2 0.0 7e-35 120.8 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III SWIRM PF04433.17 KPI35289.1 - 6.2e-31 106.6 0.0 1.4e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KPI35289.1 - 2.9e-26 91.2 7.9 2.9e-26 91.2 7.9 2.1 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KPI35289.1 - 8.1e-10 38.7 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPI35289.1 - 8.4e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KPI35289.1 - 0.56 10.1 3.5 0.75 9.7 0.0 2.7 3 0 0 3 3 3 0 Myb DNA-binding like FAT PF02259.23 KPI35289.1 - 0.91 8.7 5.2 0.24 10.6 1.0 1.9 2 0 0 2 2 2 0 FAT domain ZZ PF00569.17 KPI35289.1 - 4.9 7.0 6.6 0.2 11.5 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Hid1 PF12722.7 KPI35290.1 - 5.4e-296 984.1 0.0 4.5e-295 981.0 0.0 1.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KPI35290.1 - 5.9e-108 361.9 0.0 7.2e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SPX PF03105.19 KPI35290.1 - 3.5 7.5 11.6 6.2 6.6 11.6 1.3 1 0 0 1 1 1 0 SPX domain Fungal_trans PF04082.18 KPI35291.1 - 1.9e-31 109.1 0.8 6.2e-31 107.4 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zwint PF15556.6 KPI35291.1 - 0.41 10.1 2.4 0.46 9.9 0.8 1.8 2 0 0 2 2 2 0 ZW10 interactor F-box PF00646.33 KPI35292.1 - 8.5e-06 25.5 0.3 1.9e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPI35292.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF900 PF05990.12 KPI35293.1 - 0.003 17.1 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 KPI35293.1 - 0.0072 15.9 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) zf-H2C2_2 PF13465.6 KPI35293.1 - 0.0096 16.3 1.1 1.7 9.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI35293.1 - 0.021 15.6 1.2 0.05 14.5 1.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 KPI35293.1 - 0.022 15.0 0.5 0.04 14.2 0.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Hydrolase_4 PF12146.8 KPI35293.1 - 0.035 13.4 0.0 0.077 12.3 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 KPI35293.1 - 0.24 11.9 1.8 0.45 11.1 1.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.7 KPI35293.1 - 0.35 11.4 11.5 5.9 7.4 9.9 2.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF3176 PF11374.8 KPI35294.1 - 2.8e-27 95.0 0.8 7.2e-27 93.7 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Myb_DNA-bind_6 PF13921.6 KPI35296.1 - 6.3e-11 42.4 2.2 2e-10 40.7 2.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KPI35296.1 - 2.5e-08 34.0 6.1 3.3e-06 27.2 1.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 KPI35296.1 - 6e-06 26.7 3.2 0.011 16.5 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI35296.1 - 3.9e-05 23.8 5.2 0.028 14.8 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KPI35296.1 - 0.0008 19.6 2.0 0.089 13.1 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KPI35296.1 - 0.0021 18.0 3.2 0.0025 17.8 0.6 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPI35296.1 - 0.0082 16.5 3.0 1.2 9.5 0.3 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KPI35296.1 - 0.0085 16.5 0.8 0.018 15.4 0.2 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KPI35296.1 - 0.01 15.6 0.2 0.053 13.3 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type Elf1 PF05129.13 KPI35296.1 - 1.1 9.3 5.0 0.3 11.2 0.4 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 KPI35296.1 - 4 8.0 4.4 20 5.8 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Fungal_trans PF04082.18 KPI35297.1 - 1.4e-15 57.1 0.0 2.1e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35297.1 - 2.3e-08 34.0 11.0 6.5e-08 32.6 11.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B561 PF03188.16 KPI35299.1 - 2e-07 31.2 10.2 2e-07 31.2 10.2 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KPI35299.1 - 0.00011 21.9 5.3 0.00011 21.9 5.3 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) CDH-cyt PF16010.5 KPI35299.1 - 0.0006 19.6 0.9 0.0029 17.3 0.9 2.0 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase IncE PF17627.2 KPI35299.1 - 0.019 15.0 1.5 0.046 13.7 1.5 1.6 1 0 0 1 1 1 0 Inclusion membrane protein E DUF4231 PF14015.6 KPI35299.1 - 1.2 9.6 8.2 1.6 9.2 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Motile_Sperm PF00635.26 KPI35300.1 - 1.5e-28 98.8 0.0 3.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ABC_tran_CTD PF16326.5 KPI35300.1 - 0.024 14.9 1.9 0.045 14.0 1.9 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain OmpH PF03938.14 KPI35300.1 - 0.028 14.8 3.6 0.054 13.8 3.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) COG5 PF10392.9 KPI35300.1 - 0.031 14.5 0.2 0.052 13.7 0.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Phage_GP20 PF06810.11 KPI35300.1 - 0.037 13.8 0.8 0.078 12.8 0.8 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF756 PF05506.12 KPI35300.1 - 0.043 14.7 0.1 0.13 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF756) adh_short PF00106.25 KPI35300.1 - 0.17 11.4 1.9 7 6.0 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase FliG_C PF01706.16 KPI35300.1 - 0.27 11.5 4.4 0.24 11.6 1.8 2.1 2 0 0 2 2 2 0 FliG C-terminal domain Mitofilin PF09731.9 KPI35300.1 - 0.46 9.3 8.6 0.75 8.6 8.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CwsA PF10814.8 KPI35300.1 - 0.48 10.6 7.9 7.7 6.7 6.3 2.3 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Glyco_hydro_35 PF01301.19 KPI35301.1 - 1.1e-88 297.9 0.4 1.5e-88 297.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KPI35301.1 - 9e-53 178.8 1.0 1.8e-52 177.8 1.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KPI35301.1 - 1.7e-15 57.6 1.8 7.3e-15 55.5 0.5 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KPI35301.1 - 2.3e-14 52.7 0.0 9.4e-14 50.7 0.0 2.1 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 p450 PF00067.22 KPI35302.1 - 3.9e-49 167.7 0.0 5.1e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_oprn_chp PF09534.10 KPI35303.1 - 0.00013 21.9 0.3 0.00014 21.7 0.3 1.0 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) His_Phos_2 PF00328.22 KPI35304.1 - 4.2e-22 79.0 0.0 5.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sulfotransfer_3 PF13469.6 KPI35304.1 - 0.011 16.2 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family Peptidase_M19 PF01244.21 KPI35305.1 - 2.8e-90 302.7 0.0 3.4e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF4690 PF15756.5 KPI35305.1 - 0.029 14.9 0.0 0.064 13.9 0.0 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DIPSY PF11763.8 KPI35306.1 - 0.034 14.3 0.0 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Cell-wall adhesin ligand-binding C-terminal Collagen_bind_2 PF12904.7 KPI35306.1 - 0.15 12.1 0.9 4.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase LigB PF02900.18 KPI35307.1 - 8.2e-34 116.9 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Gp_dh_C PF02800.20 KPI35308.1 - 8.3e-55 184.7 0.0 1.2e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KPI35308.1 - 8.6e-40 135.2 0.1 1.9e-39 134.1 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KPI35308.1 - 0.0063 16.6 0.3 0.019 15.1 0.1 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KPI35308.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ICL PF00463.21 KPI35309.1 - 1.2e-91 307.8 0.0 1.4e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KPI35309.1 - 2.4e-08 33.7 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2935 PF11155.8 KPI35309.1 - 3.1e-05 24.3 0.0 5.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) RNA_pol_L_2 PF13656.6 KPI35310.1 - 6.7e-22 77.1 0.0 9.6e-22 76.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KPI35310.1 - 6.6e-08 31.9 0.0 9.8e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mt_ATP-synt_D PF05873.12 KPI35310.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) s48_45 PF07422.13 KPI35310.1 - 0.16 12.6 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain UBA PF00627.31 KPI35311.1 - 7.3e-05 22.6 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KPI35311.1 - 7.7e-05 22.8 0.3 0.00022 21.4 0.0 2.0 2 0 0 2 2 2 1 UBX domain DUF5010_C PF18099.1 KPI35311.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 DUF5010 C-terminal domain zf-C2HE PF16278.5 KPI35311.1 - 0.36 11.3 0.1 0.36 11.3 0.1 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger THRAP3_BCLAF1 PF15440.6 KPI35311.1 - 1 8.3 29.5 1.3 7.9 29.5 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family SOBP PF15279.6 KPI35311.1 - 3.2 8.3 9.6 4 8.0 9.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CpXC PF14353.6 KPI35311.1 - 9 6.4 10.5 45 4.1 10.3 2.4 1 1 0 1 1 1 0 CpXC protein BetaGal_dom4_5 PF13364.6 KPI35312.1 - 1.2e-29 103.2 0.0 1.7e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Syja_N PF02383.18 KPI35313.1 - 2.5e-76 257.0 0.0 4.9e-76 256.1 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain MFS_1 PF07690.16 KPI35315.1 - 6.6e-25 87.8 17.8 8.2e-25 87.5 17.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35315.1 - 1.1e-05 24.5 10.1 3e-05 23.1 9.8 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.16 KPI35315.1 - 0.075 12.7 2.8 0.059 13.1 0.3 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF1127 PF06568.11 KPI35315.1 - 0.1 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) NmrA PF05368.13 KPI35316.1 - 1.4e-31 109.9 0.0 1.7e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI35316.1 - 6.9e-12 45.6 0.3 2.3e-11 43.9 0.3 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI35316.1 - 3.6e-08 33.2 0.1 3.5e-06 26.6 0.3 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI35316.1 - 1.1e-06 27.9 0.3 1.7e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KPI35316.1 - 7e-06 26.1 0.2 1.3e-05 25.2 0.2 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KPI35316.1 - 1.6e-05 25.3 0.2 4.4e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 KPI35316.1 - 0.0001 21.9 0.2 0.0003 20.4 0.1 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus GDP_Man_Dehyd PF16363.5 KPI35316.1 - 0.0029 17.1 0.1 0.0055 16.2 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KPI35316.1 - 0.0031 17.8 0.7 0.0066 16.7 0.7 1.6 1 0 0 1 1 1 1 TrkA-N domain Arg_repressor PF01316.21 KPI35316.1 - 0.018 14.7 0.0 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain Cas_Cas02710 PF09670.10 KPI35316.1 - 0.031 13.1 0.1 0.049 12.4 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Polysacc_synt_2 PF02719.15 KPI35316.1 - 0.036 13.2 0.3 0.052 12.7 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.16 KPI35316.1 - 0.08 13.7 0.2 0.2 12.4 0.2 1.7 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.25 KPI35316.1 - 0.085 12.3 0.5 0.15 11.5 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Sua5_yciO_yrdC PF01300.18 KPI35317.1 - 0.00073 19.1 0.0 0.0009 18.8 0.0 1.3 1 1 0 1 1 1 1 Telomere recombination Fungal_trans PF04082.18 KPI35318.1 - 3.2e-06 26.4 0.0 7.4e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mak10 PF04112.13 KPI35318.1 - 0.15 11.6 0.2 0.39 10.2 0.2 1.6 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Polysacc_deac_1 PF01522.21 KPI35320.1 - 6.2e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 KPI35321.1 - 2.4e-20 72.7 0.0 3.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KPI35322.1 - 7.7e-17 61.4 0.0 1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35322.1 - 5.4e-07 29.4 0.0 7.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35322.1 - 0.0028 17.6 0.0 0.0061 16.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI35322.1 - 0.0092 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ferritin_2 PF13668.6 KPI35324.1 - 1.5e-15 57.6 0.0 3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Ferritin-like domain MF_alpha_N PF05436.11 KPI35324.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Rubrerythrin PF02915.17 KPI35324.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Rubrerythrin DAO PF01266.24 KPI35325.1 - 7.7e-37 127.7 1.5 1e-36 127.3 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI35325.1 - 0.002 18.3 0.1 0.0055 16.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI35325.1 - 0.002 17.4 0.1 0.0036 16.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPI35325.1 - 0.0028 17.0 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI35325.1 - 0.0063 16.5 0.7 0.19 11.7 0.4 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 KPI35325.1 - 0.028 13.0 0.1 0.048 12.2 0.1 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 KPI35325.1 - 0.11 11.6 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KPI35325.1 - 0.2 10.4 0.1 0.29 9.9 0.1 1.1 1 0 0 1 1 1 0 MCRA family adh_short PF00106.25 KPI35326.1 - 3.1e-30 105.1 1.0 3.4e-19 69.1 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35326.1 - 1.7e-17 63.8 2.1 3.1e-10 40.0 0.4 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35326.1 - 2.4e-08 34.1 0.5 3.8e-08 33.5 0.2 1.6 2 0 0 2 2 2 1 KR domain CoA_binding_2 PF13380.6 KPI35326.1 - 0.082 13.4 0.1 0.95 10.0 0.1 2.3 2 1 0 2 2 2 0 CoA binding domain Transp_cyt_pur PF02133.15 KPI35327.1 - 5e-95 318.9 32.5 5.8e-95 318.6 32.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin His_Phos_2 PF00328.22 KPI35328.1 - 1.2e-38 133.5 0.0 2.3e-38 132.6 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1720 PF08226.11 KPI35328.1 - 4.5 7.8 9.1 0.92 10.0 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) Pho88 PF10032.9 KPI35329.1 - 1.1e-80 269.2 0.1 1.3e-80 269.0 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) MFS_1 PF07690.16 KPI35330.1 - 4e-14 52.3 5.6 1.5e-07 30.7 2.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35330.1 - 3.3e-07 29.5 5.2 5.8e-07 28.7 0.4 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter NMO PF03060.15 KPI35331.1 - 1.6e-16 60.6 0.7 6.6e-13 48.7 0.1 2.9 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KPI35331.1 - 0.027 13.5 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Macoilin PF09726.9 KPI35332.1 - 0.12 10.9 0.7 0.16 10.5 0.7 1.1 1 0 0 1 1 1 0 Macoilin family Hist_deacetyl PF00850.19 KPI35333.1 - 2e-81 273.9 0.0 4e-81 272.8 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.9 KPI35333.1 - 1.5e-78 263.5 0.0 2e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain ADH_N PF08240.12 KPI35334.1 - 5.7e-09 35.8 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI35334.1 - 1.2e-08 35.0 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI35334.1 - 0.072 13.0 0.1 0.19 11.6 0.1 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase DUF3185 PF11381.8 KPI35335.1 - 0.017 15.1 1.1 0.021 14.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) TMEM40 PF15817.5 KPI35335.1 - 0.066 13.0 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 40 family MFS_1 PF07690.16 KPI35336.1 - 2.1e-14 53.2 18.2 2.1e-14 53.2 18.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MNE1 PF13762.6 KPI35336.1 - 0.039 13.9 0.2 0.074 13.0 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component TauD PF02668.16 KPI35337.1 - 4.9e-43 147.9 0.0 6.7e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactamase_B PF00753.27 KPI35338.1 - 0.00063 19.8 0.1 0.0013 18.8 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI35338.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_trans_2_3 PF13632.6 KPI35339.1 - 2.1e-51 174.7 5.7 7.7e-51 172.8 5.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPI35339.1 - 1.1e-05 25.3 0.0 6.9e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPI35339.1 - 0.0083 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 AA_permease PF00324.21 KPI35340.1 - 5.4e-115 384.7 41.1 6.7e-115 384.4 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI35340.1 - 6.6e-27 94.4 40.0 8.2e-27 94.1 40.0 1.1 1 0 0 1 1 1 1 Amino acid permease TraQ PF09679.10 KPI35340.1 - 3.7 7.5 5.8 26 4.8 3.1 2.7 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) EF-hand_4 PF12763.7 KPI35341.1 - 8.4e-26 90.0 0.0 4.8e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KPI35341.1 - 1.9e-07 31.4 132.1 2.1e-05 24.9 16.5 8.0 5 2 3 8 8 8 5 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KPI35341.1 - 1.1e-05 25.8 0.1 0.0023 18.4 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KPI35341.1 - 1.9e-05 23.8 0.0 0.0035 16.8 0.0 2.5 2 0 0 2 2 2 1 EF hand WH2 PF02205.20 KPI35341.1 - 0.00019 21.2 0.1 0.00051 19.8 0.1 1.7 1 0 0 1 1 1 1 WH2 motif EF-hand_6 PF13405.6 KPI35341.1 - 0.055 13.4 0.0 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain E3_binding PF02817.17 KPI35341.1 - 0.062 13.7 0.2 0.2 12.1 0.2 1.9 1 0 0 1 1 1 0 e3 binding domain EF-hand_9 PF14658.6 KPI35341.1 - 0.077 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KPI35341.1 - 0.086 12.7 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair AhpC-TSA PF00578.21 KPI35343.1 - 1.1e-15 57.6 0.0 1.5e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI35343.1 - 8.5e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KPI35343.1 - 0.0012 19.0 0.0 0.22 11.7 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 KPI35343.1 - 0.0088 15.6 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.6 KPI35343.1 - 0.031 14.6 0.0 0.092 13.1 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 KPI35343.1 - 0.034 14.6 0.0 0.056 13.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Zn_clus PF00172.18 KPI35344.1 - 4.7e-08 33.0 9.1 8.3e-08 32.2 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KPI35345.1 - 3.2e-81 273.6 0.0 4.8e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Amidase FA_desaturase PF00487.24 KPI35346.1 - 1.7e-27 96.9 12.7 2.8e-27 96.2 12.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DIOX_N PF14226.6 KPI35346.1 - 7.2e-17 62.2 0.0 1.8e-16 61.0 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI35346.1 - 2.9e-16 59.8 0.0 7.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipid_DES PF08557.10 KPI35346.1 - 2.9e-14 52.3 0.2 7.6e-14 50.9 0.2 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M8 PF01457.16 KPI35346.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin WSC PF01822.19 KPI35347.1 - 9.6e-78 256.4 84.9 5e-18 65.1 13.8 5.8 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 KPI35347.1 - 3.2e-18 65.8 0.8 3.4e-17 62.4 0.0 3.0 4 1 1 5 5 5 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KPI35347.1 - 4.4e-15 55.7 0.0 1.4e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Peptidase_M20 PF01546.28 KPI35348.1 - 8.7e-28 97.4 0.1 2.6e-27 95.9 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI35348.1 - 9.3e-15 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPI35348.1 - 0.0084 15.8 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 DUF2254 PF10011.9 KPI35348.1 - 0.17 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) MS_channel PF00924.18 KPI35349.1 - 0.00098 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 KPI35349.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Fungal_trans PF04082.18 KPI35351.1 - 9e-24 83.9 0.1 3.9e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_16 PF00722.21 KPI35352.1 - 1.5e-15 57.1 0.7 2.7e-15 56.3 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PNKP_ligase PF16542.5 KPI35353.1 - 0.039 13.4 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain TPR_11 PF13414.6 KPI35353.1 - 0.092 12.4 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 TPR repeat BRO1 PF03097.18 KPI35353.1 - 0.1 11.4 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 BRO1-like domain TPR_14 PF13428.6 KPI35353.1 - 0.12 13.3 1.4 55 5.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NGP1NT PF08153.12 KPI35354.1 - 1.2e-48 164.6 1.6 1.9e-48 163.9 1.6 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KPI35354.1 - 9.6e-18 64.3 0.0 3.8e-14 52.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI35354.1 - 5.4e-05 22.8 0.0 0.00064 19.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KPI35354.1 - 0.00027 20.4 0.1 0.062 12.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KPI35354.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KPI35354.1 - 0.0034 17.5 0.1 0.75 9.8 0.0 3.4 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 KPI35354.1 - 0.0096 15.5 0.0 0.77 9.3 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KPI35354.1 - 0.12 12.6 0.1 28 5.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PSD3 PF07626.11 KPI35355.1 - 4 8.0 4.7 1.1e+02 3.4 2.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1587) FAD_binding_3 PF01494.19 KPI35356.1 - 3.7e-13 49.4 0.0 7.1e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI35356.1 - 0.014 15.6 0.2 0.032 14.5 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KPI35356.1 - 0.037 13.1 0.0 0.35 9.9 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KPI35356.1 - 0.19 10.9 0.5 0.33 10.1 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MutS_V PF00488.21 KPI35358.1 - 7.6e-46 156.5 0.0 1.7e-44 152.1 0.0 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPI35358.1 - 2.4e-18 67.0 0.3 4.7e-18 66.1 0.1 1.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KPI35358.1 - 0.00023 21.4 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Aldolase_II PF00596.21 KPI35359.1 - 2.1e-43 148.4 0.2 3.1e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Zn_clus PF00172.18 KPI35361.1 - 9.2e-09 35.3 9.1 1.5e-08 34.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI35361.1 - 0.0043 15.9 0.5 0.0059 15.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1996 PF09362.10 KPI35362.1 - 2e-63 214.5 2.1 3.2e-63 213.9 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) S_tail_recep_bd PF14928.6 KPI35362.1 - 0.01 16.5 0.1 0.026 15.1 0.1 1.8 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Amidase PF01425.21 KPI35363.1 - 3.1e-70 237.4 0.5 4.3e-69 233.6 0.5 2.5 1 1 0 1 1 1 1 Amidase p450 PF00067.22 KPI35364.1 - 5.8e-56 190.2 0.0 7.9e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2-Hacid_dh_C PF02826.19 KPI35365.1 - 1e-36 126.0 0.2 4.7e-36 123.8 0.1 2.1 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI35365.1 - 2.8e-23 82.0 0.1 3.6e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI35365.1 - 4.9e-10 39.8 1.1 1.8e-06 28.2 0.4 2.4 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPI35365.1 - 2.3e-06 28.1 0.3 1.4e-05 25.5 0.1 2.4 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KPI35365.1 - 2.7e-05 23.6 0.4 0.00035 19.9 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KPI35365.1 - 5.5e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPI35365.1 - 0.00057 20.1 1.0 0.26 11.5 0.1 2.6 2 2 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain ELFV_dehydrog PF00208.21 KPI35365.1 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_Gly3P_dh_N PF01210.23 KPI35365.1 - 0.0046 16.9 0.5 0.021 14.8 0.1 2.3 2 2 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KPI35365.1 - 0.0055 17.0 1.7 0.11 12.7 0.1 2.7 2 2 0 2 2 2 1 TrkA-N domain XdhC_C PF13478.6 KPI35365.1 - 0.015 15.8 0.1 0.082 13.4 0.1 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Shikimate_DH PF01488.20 KPI35365.1 - 0.057 13.5 1.0 0.22 11.6 0.2 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KPI35365.1 - 0.096 12.2 0.4 0.51 9.9 0.4 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_trans_4_4 PF13579.6 KPI35365.1 - 0.12 12.8 1.4 0.35 11.3 0.1 2.3 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain IlvN PF07991.12 KPI35365.1 - 0.12 11.9 0.6 0.32 10.5 0.1 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Transp_cyt_pur PF02133.15 KPI35366.1 - 7e-105 351.3 39.8 8e-105 351.1 39.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SnoaL_2 PF12680.7 KPI35368.1 - 8.5e-06 26.4 0.0 1.1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPI35368.1 - 1.4e-05 25.4 0.0 1.9e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 KPI35368.1 - 0.042 13.6 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase 2-Hacid_dh_C PF02826.19 KPI35369.1 - 3.1e-51 173.3 0.0 3.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI35369.1 - 5.8e-06 26.0 0.0 6.9e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI35369.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 KPI35370.1 - 2.6e-18 66.4 1.1 7.8e-18 64.8 1.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI35370.1 - 1e-08 35.2 8.1 0.0015 18.2 7.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI35370.1 - 1.8e-08 34.0 3.2 0.00013 21.3 1.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI35370.1 - 1e-07 31.7 0.1 1.7e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI35370.1 - 4.5e-07 28.9 4.7 0.00032 19.5 3.9 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KPI35370.1 - 5.2e-07 29.8 3.3 8e-07 29.2 2.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI35370.1 - 3.9e-06 27.3 1.8 0.0011 19.5 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI35370.1 - 3.7e-05 23.0 7.3 8e-05 21.9 5.3 2.2 2 1 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KPI35370.1 - 6.4e-05 22.2 1.5 9.9e-05 21.6 1.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPI35370.1 - 0.00056 18.9 2.0 0.28 10.0 1.3 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 KPI35370.1 - 0.0056 16.0 2.9 1.9 7.7 1.6 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KPI35370.1 - 0.0078 16.1 0.6 0.014 15.2 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KPI35370.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KPI35370.1 - 0.024 13.9 3.9 1.3 8.2 5.6 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3603 PF12227.8 KPI35370.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) AlaDh_PNT_C PF01262.21 KPI35370.1 - 0.037 13.3 0.6 0.071 12.4 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KPI35370.1 - 0.063 12.3 4.5 0.69 8.9 4.5 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.9 KPI35370.1 - 0.37 10.6 1.4 5.1 7.0 0.3 2.3 2 0 0 2 2 2 0 Rossmann-like domain adh_short_C2 PF13561.6 KPI35371.1 - 8.4e-60 202.2 1.9 1.1e-59 201.9 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35371.1 - 5.4e-47 159.8 1.1 6.4e-47 159.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35371.1 - 1.9e-06 27.9 0.2 3e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KPI35371.1 - 0.00088 19.9 0.1 0.0026 18.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain B12-binding PF02310.19 KPI35371.1 - 0.11 12.5 0.2 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain Methyltransf_11 PF08241.12 KPI35371.1 - 0.11 13.1 0.0 0.87 10.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KPI35372.1 - 3.9e-09 37.1 0.0 8.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI35372.1 - 5.6e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI35372.1 - 1.8e-07 31.1 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI35372.1 - 4e-06 26.7 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI35372.1 - 6.7e-05 23.6 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KPI35372.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KPI35372.1 - 0.00097 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPI35372.1 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KPI35372.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Adhesin_Dr PF04619.12 KPI35372.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Dr-family adhesin Lactamase_B PF00753.27 KPI35373.1 - 4.8e-06 26.7 1.5 1.9e-05 24.8 1.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI35373.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain F_bP_aldolase PF01116.20 KPI35374.1 - 8.9e-63 212.4 0.0 9.9e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II p450 PF00067.22 KPI35375.1 - 0.059 12.1 1.7 1.2 7.8 1.7 2.2 1 1 0 1 1 1 0 Cytochrome P450 EthD PF07110.11 KPI35376.1 - 3.9e-13 50.4 0.1 4.8e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPI35376.1 - 3.6e-05 24.2 0.3 4.6e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DDE_Tnp_ISL3 PF01610.17 KPI35376.1 - 0.048 13.4 0.0 0.052 13.3 0.0 1.0 1 0 0 1 1 1 0 Transposase Peptidase_M16_M PF16187.5 KPI35377.1 - 1.5e-90 303.3 1.9 3.6e-90 302.1 1.9 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KPI35377.1 - 1.7e-32 112.9 0.4 5.8e-23 81.8 0.0 3.6 4 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPI35377.1 - 9.5e-32 110.0 0.9 5.9e-31 107.5 0.9 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) LisH_TPL PF17814.1 KPI35377.1 - 0.098 12.3 0.2 15 5.4 0.3 3.5 4 0 0 4 4 4 0 LisH-like dimerisation domain DUF3990 PF13151.6 KPI35378.1 - 0.17 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) ABA_WDS PF02496.16 KPI35379.1 - 5.7e-05 23.5 15.5 0.00064 20.1 9.1 9.0 8 1 0 9 9 9 3 ABA/WDS induced protein Borrelia_P83 PF05262.11 KPI35379.1 - 4.5 5.6 40.1 7.4 4.9 40.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Cu-oxidase_3 PF07732.15 KPI35380.1 - 4.6e-38 129.9 3.5 4.6e-37 126.7 1.2 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KPI35380.1 - 3.4e-26 92.3 0.1 9.2e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPI35380.1 - 3.6e-06 26.8 7.9 0.21 11.3 0.9 4.3 3 2 1 4 4 4 3 Multicopper oxidase VP4_2 PF08935.10 KPI35380.1 - 0.0071 16.9 1.2 1.1 9.9 0.4 2.8 2 0 0 2 2 2 2 Viral protein VP4 subunit Hap4_Hap_bind PF10297.9 KPI35381.1 - 1.6e-08 34.4 6.1 3.6e-08 33.3 6.1 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KPI35381.1 - 3.2e-08 33.6 13.0 4.5e-05 23.5 6.9 2.3 1 1 1 2 2 2 2 bZIP transcription factor ATG16 PF08614.11 KPI35381.1 - 0.00062 20.1 1.0 0.0015 18.8 1.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 KPI35381.1 - 0.0047 17.2 3.9 0.0077 16.5 3.9 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF812 PF05667.11 KPI35381.1 - 0.0056 15.6 0.4 0.0079 15.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 KPI35381.1 - 0.013 15.0 2.2 0.02 14.4 2.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2381 PF09544.10 KPI35381.1 - 0.031 13.8 0.3 0.057 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Phage_Mu_Gam PF07352.12 KPI35381.1 - 0.037 13.9 1.1 0.066 13.1 1.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Filament PF00038.21 KPI35381.1 - 0.038 13.6 3.3 0.058 13.0 3.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein dsrm PF00035.26 KPI35381.1 - 0.071 13.8 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Macoilin PF09726.9 KPI35381.1 - 0.13 10.8 3.5 0.23 10.0 3.5 1.3 1 0 0 1 1 1 0 Macoilin family HAUS4 PF14735.6 KPI35381.1 - 0.18 11.5 1.5 0.31 10.7 1.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 SlyX PF04102.12 KPI35381.1 - 0.22 12.2 1.4 0.56 10.9 1.3 1.8 1 1 0 1 1 1 0 SlyX APG6_N PF17675.1 KPI35381.1 - 0.29 11.7 5.5 0.51 10.9 5.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_2 PF07716.15 KPI35381.1 - 0.39 10.8 13.4 0.56 10.3 11.7 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Tmemb_cc2 PF10267.9 KPI35381.1 - 0.53 9.4 3.2 0.15 11.2 0.3 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF3583 PF12126.8 KPI35381.1 - 1.6 8.1 5.6 2 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) bZIP_Maf PF03131.17 KPI35381.1 - 2.1 8.9 9.2 10 6.7 9.2 2.0 1 1 0 1 1 1 0 bZIP Maf transcription factor LRRFIP PF09738.9 KPI35381.1 - 3 7.3 8.3 6 6.2 6.6 2.0 1 1 1 2 2 2 0 LRRFIP family Spc29 PF17082.5 KPI35382.1 - 0.0085 16.0 2.6 0.021 14.7 2.6 1.7 1 0 0 1 1 1 1 Spindle Pole Component 29 Mei4 PF13971.6 KPI35382.1 - 0.031 13.8 2.0 0.059 12.9 2.0 1.4 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Exonuc_VII_L PF02601.15 KPI35382.1 - 0.12 11.9 8.8 0.24 10.9 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 KPI35382.1 - 0.14 12.6 1.6 15 6.1 0.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 KPI35382.1 - 0.27 10.3 11.3 0.77 8.8 11.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KPI35382.1 - 0.55 10.3 9.3 1.3 9.1 9.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KPI35382.1 - 0.94 9.9 7.9 7.9 6.9 2.5 2.9 2 0 0 2 2 2 0 Csm1 N-terminal domain FapA PF03961.13 KPI35382.1 - 1 7.9 3.0 1.6 7.3 3.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 KPI35382.1 - 1.4 7.4 11.6 2.4 6.6 11.6 1.3 1 0 0 1 1 1 0 Macoilin family TMF_DNA_bd PF12329.8 KPI35382.1 - 1.8 8.6 13.7 1.2 9.2 5.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KPI35382.1 - 3.1 8.5 9.3 0.88 10.2 0.6 3.3 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 KPI35382.1 - 6.3 6.6 19.4 0.27 11.0 2.5 3.9 3 1 1 4 4 4 0 Septum formation initiator Fib_alpha PF08702.10 KPI35382.1 - 6.5 6.9 7.4 17 5.6 6.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.9 KPI35382.1 - 6.7 6.8 9.5 4.3 7.4 2.2 3.2 1 1 2 3 3 3 0 Short coiled-coil protein DUF4407 PF14362.6 KPI35382.1 - 6.7 6.0 12.3 11 5.3 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 KPI35382.1 - 9.9 6.6 10.5 3.7 8.0 1.9 3.4 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MCM PF00493.23 KPI35383.1 - 1.4e-97 325.2 0.1 2.4e-97 324.5 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPI35383.1 - 6.1e-30 103.7 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPI35383.1 - 1.5e-23 83.0 2.2 3e-23 82.0 2.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPI35383.1 - 5.5e-12 46.2 0.0 1.7e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPI35383.1 - 9.9e-07 28.3 0.0 1.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KPI35383.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BUD22 PF09073.10 KPI35384.1 - 8.6 5.6 28.1 1.9 7.8 12.5 2.1 2 0 0 2 2 2 0 BUD22 Transp_cyt_pur PF02133.15 KPI35386.1 - 2.5e-84 283.6 39.8 1.1e-83 281.4 39.8 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_3 PF07859.13 KPI35387.1 - 5.8e-61 206.0 0.0 8.6e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI35387.1 - 0.00047 19.1 0.1 0.00095 18.1 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPI35387.1 - 0.0078 15.7 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Viral_coat PF00729.18 KPI35387.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein (S domain) Say1_Mug180 PF10340.9 KPI35387.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Tim17 PF02466.19 KPI35388.1 - 2.6e-24 85.7 16.8 1.5e-23 83.3 16.8 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Na_Ca_ex PF01699.24 KPI35389.1 - 6.5e-23 81.4 24.3 7.1e-16 58.5 11.7 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KPI35389.1 - 2.2e-15 57.1 11.6 2.2e-15 57.1 11.6 3.9 4 0 0 4 4 4 1 Inner membrane component domain ATP1G1_PLM_MAT8 PF02038.16 KPI35389.1 - 1.2 8.6 3.2 1 8.8 0.4 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family MFS_1 PF07690.16 KPI35390.1 - 4.9e-19 68.5 35.6 4.9e-19 68.5 35.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.18 KPI35391.1 - 5.2e-09 35.8 1.6 8.1e-09 35.2 1.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein OPT PF03169.15 KPI35392.1 - 2.5e-199 663.9 40.8 2.9e-199 663.7 40.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.27 KPI35394.1 - 1.1e-59 198.4 1.4 3e-24 84.7 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI35394.1 - 0.063 12.4 0.1 0.55 9.3 0.0 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease PT-VENN PF04829.13 KPI35394.1 - 0.091 12.9 0.1 4.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif RdRP PF05183.12 KPI35395.1 - 2.2e-170 568.2 0.0 3.6e-170 567.5 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KPI35395.1 - 0.0093 15.8 0.0 0.056 13.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.29 KPI35396.1 - 5e-47 160.6 0.0 7.9e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI35396.1 - 1.6e-12 47.6 0.0 1.8e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KPI35396.1 - 0.02 14.4 0.0 9.9 5.5 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Rrp15p PF07890.12 KPI35398.1 - 1.8e-36 125.4 9.6 1.8e-36 125.4 9.6 2.4 3 0 0 3 3 3 1 Rrp15p MARVEL PF01284.23 KPI35399.1 - 2.3e-05 24.5 10.2 4e-05 23.7 10.3 1.4 1 1 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 KPI35399.1 - 6.6 6.2 13.7 0.88 9.1 8.6 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein HlyD_D4 PF16572.5 KPI35400.1 - 0.004 17.0 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 Long alpha hairpin domain of cation efflux system protein, CusB Zip PF02535.22 KPI35400.1 - 4.6 6.4 3.9 6.4 5.9 3.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PhoD PF09423.10 KPI35401.1 - 1.3e-35 123.1 0.0 2.9e-35 121.9 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KPI35401.1 - 0.00016 22.1 0.4 0.0004 20.9 0.4 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain GLE1 PF07817.13 KPI35402.1 - 5.1e-26 91.4 0.1 1.6e-24 86.5 0.1 2.3 1 1 0 1 1 1 1 GLE1-like protein RNB PF00773.19 KPI35403.1 - 2.3e-87 293.4 0.0 4.3e-87 292.5 0.0 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KPI35403.1 - 4.9e-26 90.9 0.0 1.6e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KPI35403.1 - 9.5e-26 89.6 0.0 2.3e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KPI35403.1 - 0.00028 21.0 0.0 0.032 14.4 0.0 2.8 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 KPI35403.1 - 0.0016 18.2 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KPI35403.1 - 0.06 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 S1 domain NPR3 PF03666.13 KPI35403.1 - 5.7 5.6 8.1 0.27 10.0 0.5 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 EF1_GNE PF00736.19 KPI35404.1 - 1.1e-30 105.6 5.3 6.3e-30 103.2 4.0 2.5 3 0 0 3 3 3 1 EF-1 guanine nucleotide exchange domain eIF-5_eIF-2B PF01873.17 KPI35404.1 - 1.1e-10 41.4 1.2 7.3e-08 32.3 1.2 2.5 1 1 0 1 1 1 1 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.17 KPI35404.1 - 0.004 16.8 2.6 0.0084 15.8 2.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KPI35404.1 - 8 6.1 10.0 0.94 9.0 5.5 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding HET PF06985.11 KPI35405.1 - 2.6e-14 53.8 0.0 5.9e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fer2 PF00111.27 KPI35406.1 - 4.2e-14 52.3 1.1 6.1e-14 51.7 1.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Hemerythrin PF01814.23 KPI35407.1 - 4.4e-07 30.6 1.8 6.4e-07 30.1 1.8 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Putative_PNPOx PF01243.20 KPI35408.1 - 7.6e-07 29.2 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_90 PF05686.12 KPI35410.1 - 3.7e-15 55.8 6.4 7.5e-13 48.1 4.3 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF1962 PF09227.10 KPI35410.1 - 0.075 13.4 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) DUF4863 PF16155.5 KPI35411.1 - 4.2e-69 231.3 0.0 4.9e-69 231.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) LCIB_C_CA PF18599.1 KPI35411.1 - 0.23 10.7 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases OmpH PF03938.14 KPI35412.1 - 9.3e-06 26.0 9.9 0.0011 19.3 1.4 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KPI35412.1 - 0.0083 15.0 20.9 0.23 10.3 7.1 3.1 2 1 0 3 3 3 2 Spc7 kinetochore protein Ly49 PF08391.10 KPI35412.1 - 0.01 16.2 0.7 0.03 14.7 0.0 2.1 3 0 0 3 3 1 0 Ly49-like protein, N-terminal region Fez1 PF06818.15 KPI35412.1 - 0.038 14.4 16.5 0.41 11.1 16.5 2.4 1 1 0 1 1 1 0 Fez1 HIP1_clath_bdg PF16515.5 KPI35412.1 - 0.052 14.2 14.1 1.2 9.8 0.1 3.6 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 KPI35412.1 - 0.061 13.1 18.7 0.14 12.0 7.4 3.4 3 0 0 3 3 3 0 Septum formation initiator BLOC1_2 PF10046.9 KPI35412.1 - 0.065 13.5 14.2 1.9 8.9 0.1 4.1 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HOOK PF05622.12 KPI35412.1 - 0.071 11.2 14.4 0.19 9.8 14.1 1.6 1 1 0 1 1 1 0 HOOK protein MAD PF05557.13 KPI35412.1 - 0.077 11.4 12.8 0.12 10.7 12.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein COG5 PF10392.9 KPI35412.1 - 0.094 12.9 9.8 3.9 7.7 0.2 3.6 2 1 2 4 4 4 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 KPI35412.1 - 0.1 11.9 21.8 0.019 14.4 16.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KPI35412.1 - 0.11 12.3 9.2 0.059 13.1 4.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Med9 PF07544.13 KPI35412.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.6 2 2 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin_1 PF12718.7 KPI35412.1 - 0.19 11.9 16.8 0.49 10.5 3.8 2.8 1 1 0 1 1 1 0 Tropomyosin like V_ATPase_I PF01496.19 KPI35412.1 - 0.23 9.3 1.1 0.39 8.6 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Streptin-Immun PF11083.8 KPI35412.1 - 0.25 11.8 3.5 1.4 9.4 1.7 2.6 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DASH_Spc34 PF08657.10 KPI35412.1 - 0.28 10.9 4.8 0.14 12.0 1.9 1.9 1 1 0 1 1 1 0 DASH complex subunit Spc34 CdvA PF18822.1 KPI35412.1 - 0.29 11.0 11.3 0.94 9.3 0.3 3.6 3 1 0 3 3 3 0 CdvA-like coiled-coil domain YlqD PF11068.8 KPI35412.1 - 0.31 11.4 7.8 2 8.8 2.0 2.5 2 0 0 2 2 2 0 YlqD protein JIP_LZII PF16471.5 KPI35412.1 - 0.33 11.2 0.1 0.33 11.2 0.1 3.7 4 1 1 5 5 3 0 JNK-interacting protein leucine zipper II AAA_13 PF13166.6 KPI35412.1 - 0.37 9.4 10.2 0.23 10.0 8.7 1.3 1 1 0 1 1 1 0 AAA domain ZapB PF06005.12 KPI35412.1 - 0.38 11.2 17.6 0.25 11.8 1.1 3.6 2 1 1 3 3 3 0 Cell division protein ZapB SlyX PF04102.12 KPI35412.1 - 0.43 11.2 14.9 4.3 8.0 0.1 4.5 4 1 0 4 4 3 0 SlyX Golgin_A5 PF09787.9 KPI35412.1 - 0.45 9.9 15.0 2.3 7.6 6.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 LPP PF04728.13 KPI35412.1 - 0.46 10.9 0.2 0.46 10.9 0.2 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF1192 PF06698.11 KPI35412.1 - 0.54 10.3 0.1 0.54 10.3 0.1 3.9 3 1 1 4 4 3 0 Protein of unknown function (DUF1192) LegC3_N PF18654.1 KPI35412.1 - 0.56 9.4 13.0 1.3 8.2 9.9 2.1 1 1 1 2 2 2 0 LegC3 N-terminal coiled-coil domain YabA PF06156.13 KPI35412.1 - 0.64 10.7 8.0 13 6.5 0.5 3.4 2 1 1 3 3 3 0 Initiation control protein YabA YscO-like PF16789.5 KPI35412.1 - 0.67 10.0 13.6 0.097 12.7 8.5 1.9 1 1 1 2 2 2 0 YscO-like protein Bacillus_HBL PF05791.11 KPI35412.1 - 0.84 9.4 9.4 0.99 9.2 2.5 2.9 2 1 1 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 KPI35412.1 - 1.2 9.2 15.5 3.1 7.9 2.3 2.7 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KPI35412.1 - 1.4 9.1 4.6 1.6 8.9 1.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 KPI35412.1 - 1.5 8.2 19.2 0.26 10.6 3.5 3.1 1 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KPI35412.1 - 1.5 8.0 15.8 3.1 7.0 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rootletin PF15035.6 KPI35412.1 - 1.6 8.7 11.2 0.75 9.8 7.8 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PRKG1_interact PF15898.5 KPI35412.1 - 1.9 9.4 17.6 7.9 7.5 3.3 3.5 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KPI35412.1 - 2 8.9 25.3 11 6.5 16.9 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Rho_Binding PF08912.11 KPI35412.1 - 2 9.3 14.4 17 6.3 0.2 4.7 5 1 0 5 5 4 0 Rho Binding DUF4482 PF14818.6 KPI35412.1 - 2.2 9.1 11.6 0.65 10.9 1.3 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF4482) Csm1_N PF18504.1 KPI35412.1 - 2.3 8.6 14.3 0.74 10.2 0.1 4.0 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF16 PF01519.16 KPI35412.1 - 2.9 8.4 7.2 15 6.1 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Cluap1 PF10234.9 KPI35412.1 - 3.3 7.0 13.0 0.9 8.9 5.4 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 CENP-F_leu_zip PF10473.9 KPI35412.1 - 3.5 7.6 17.8 4.1 7.4 4.9 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 KPI35412.1 - 3.8 7.2 17.2 0.15 11.7 0.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KPI35412.1 - 3.8 7.6 6.9 6.1 6.9 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 KPI35412.1 - 5.3 7.2 17.7 6.2 7.0 0.2 3.7 4 0 0 4 4 3 0 Centrosome localisation domain of PPC89 FAM76 PF16046.5 KPI35412.1 - 5.7 6.2 7.8 9.2 5.5 3.2 2.2 1 1 1 2 2 2 0 FAM76 protein FlaC_arch PF05377.11 KPI35412.1 - 6 7.3 7.4 42 4.6 0.5 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KPI35412.1 - 6.3 6.9 13.9 7.8 6.6 2.0 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 KPI35412.1 - 6.3 6.8 18.8 0.91 9.5 1.8 3.9 3 1 1 4 4 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 KPI35412.1 - 7 6.1 11.2 12 5.4 10.7 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 KPI35412.1 - 8.1 6.7 15.3 7.3 6.8 4.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Lipase_chap PF03280.14 KPI35412.1 - 9.1 6.2 17.1 0.064 13.2 5.0 2.7 3 1 0 3 3 2 0 Proteobacterial lipase chaperone protein DUF2203 PF09969.9 KPI35412.1 - 9.5 7.0 13.2 1.2 9.9 1.2 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CTNNBL PF08216.11 KPI35413.1 - 1.3e-25 89.5 0.1 4.2e-25 87.9 0.1 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KPI35413.1 - 0.023 14.8 0.1 5.4 7.2 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat KIX_2 PF16987.5 KPI35413.1 - 0.11 12.5 0.2 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 KIX domain GRIP PF01465.20 KPI35413.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 GRIP domain DUF913 PF06025.12 KPI35413.1 - 0.69 8.8 2.1 11 4.8 0.0 3.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) FYDLN_acid PF09538.10 KPI35413.1 - 1.7 9.4 8.6 5.9 7.6 4.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TEBP_beta PF07404.11 KPI35414.1 - 1.2 8.4 3.3 2.6 7.3 3.2 1.6 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) YnfE PF17452.2 KPI35415.1 - 0.18 12.1 1.9 0.65 10.3 1.8 2.1 2 0 0 2 2 2 0 Uncharacterized YnfE-like FPP PF05911.11 KPI35415.1 - 3.3 5.8 54.7 0.063 11.5 23.6 2.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil CENP-K PF11802.8 KPI35415.1 - 8.1 5.9 38.2 7.5 6.0 9.2 2.5 1 1 1 2 2 2 0 Centromere-associated protein K F-box PF00646.33 KPI35416.1 - 0.0036 17.1 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain Helo_like_N PF17111.5 KPI35417.1 - 8.6e-07 28.5 1.0 1.5e-06 27.7 1.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins RRM_1 PF00076.22 KPI35417.1 - 2.3e-05 24.1 0.0 4.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 KPI35418.1 - 2.1e-12 46.5 0.7 2.1e-12 46.5 0.7 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KPI35418.1 - 5.2e-06 27.3 0.2 1.1e-05 26.3 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain MutS_V PF00488.21 KPI35419.1 - 9.7e-73 244.2 0.0 2.2e-72 243.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPI35419.1 - 7.4e-42 143.7 6.0 7.4e-42 143.7 6.0 2.7 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.20 KPI35419.1 - 5.3e-21 75.0 0.0 1.2e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KPI35419.1 - 2.9e-10 40.6 0.2 9.1e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 KPI35419.1 - 0.019 14.7 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KPI35419.1 - 1.9 9.0 0.0 1.9 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KPI35420.1 - 2.9e-37 128.4 23.3 2.9e-37 128.4 23.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KPI35421.1 - 1e-45 155.9 0.9 1.4e-45 155.4 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGI PF00342.19 KPI35422.1 - 8.4e-223 740.3 5.2 2.2e-222 738.9 5.2 1.6 1 1 0 1 1 1 1 Phosphoglucose isomerase RNA_pol_Rpb2_1 PF04563.15 KPI35423.1 - 1.2e-38 132.7 0.0 2.4e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KPI35423.1 - 6.6e-33 113.9 0.0 1.3e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KPI35423.1 - 7.8e-25 86.8 0.0 1.7e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KPI35423.1 - 1e-18 67.6 0.2 3.4e-18 66.0 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KPI35423.1 - 3e-16 59.5 1.4 6.9e-16 58.3 1.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 MFS_1 PF07690.16 KPI35424.1 - 4.5e-42 144.3 38.1 8.1e-38 130.2 21.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35424.1 - 6.7e-08 31.8 5.2 6.7e-08 31.8 5.2 2.4 1 1 1 3 3 3 1 Sugar (and other) transporter BTB PF00651.31 KPI35424.1 - 8.2e-07 29.2 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LacY_symp PF01306.19 KPI35424.1 - 0.008 15.0 0.9 0.008 15.0 0.9 1.9 2 0 0 2 2 2 1 LacY proton/sugar symporter NMO PF03060.15 KPI35425.1 - 1.5e-51 175.8 4.9 2.2e-51 175.2 4.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI35425.1 - 5.2e-10 38.9 5.4 2e-09 37.0 5.4 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPI35425.1 - 1.3e-05 24.4 0.7 2.8e-05 23.3 0.7 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPI35425.1 - 0.0024 17.1 1.8 0.0036 16.5 0.7 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase p450 PF00067.22 KPI35426.1 - 5.1e-47 160.7 0.0 8.8e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NADH_u_ox_C PF12853.7 KPI35426.1 - 2.4e-24 85.1 0.1 4.6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 KPI35426.1 - 1e-15 58.1 0.1 2.4e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit COesterase PF00135.28 KPI35427.1 - 1.9e-85 287.7 0.0 2.8e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI35427.1 - 0.00024 21.0 0.2 0.0012 18.8 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI35427.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family RNB PF00773.19 KPI35428.1 - 1.1e-32 113.7 0.0 2.2e-31 109.4 0.0 2.1 1 1 0 1 1 1 1 RNB domain PRKCSH-like PF12999.7 KPI35429.1 - 3.4e-49 167.0 3.8 3.1e-27 95.5 1.0 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KPI35429.1 - 7.6e-32 110.1 0.4 1.7e-31 109.0 0.4 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KPI35429.1 - 1.5e-11 45.1 0.3 4.2e-11 43.7 0.3 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein BST2 PF16716.5 KPI35429.1 - 0.096 13.3 0.6 0.096 13.3 0.6 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Uds1 PF15456.6 KPI35429.1 - 0.22 11.7 5.7 0.64 10.2 0.8 2.6 2 1 0 2 2 2 0 Up-regulated During Septation PRCC PF10253.9 KPI35429.1 - 0.35 11.6 5.4 0.16 12.7 2.0 1.9 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting GTP-bdg_M PF16360.5 KPI35429.1 - 0.41 11.3 5.1 0.72 10.5 3.2 2.4 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region Smac_DIABLO PF09057.10 KPI35429.1 - 0.76 9.1 6.4 0.11 11.9 0.9 2.2 3 0 0 3 3 3 0 Second Mitochondria-derived Activator of Caspases DUF1664 PF07889.12 KPI35429.1 - 0.82 9.7 10.6 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ldl_recept_a PF00057.18 KPI35429.1 - 1.1 9.5 12.3 0.12 12.6 1.7 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF4407 PF14362.6 KPI35429.1 - 4.2 6.6 11.7 9.8 5.4 8.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L21e PF01157.18 KPI35430.1 - 1.8e-45 152.9 6.0 1.8e-45 152.9 6.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_15 PF18346.1 KPI35430.1 - 0.88 9.9 2.9 3.5 8.0 2.2 2.2 2 1 0 2 2 2 0 Mind bomb SH3 repeat domain AAA_33 PF13671.6 KPI35432.1 - 3.5e-11 43.4 1.0 6.4e-11 42.6 0.1 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KPI35432.1 - 1.3e-08 34.4 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KPI35432.1 - 6.7e-05 23.4 2.8 8.6e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KPI35432.1 - 0.00011 22.0 0.9 0.0046 16.7 0.8 2.1 1 1 1 2 2 2 1 AAA ATPase domain KTI12 PF08433.10 KPI35432.1 - 0.015 14.7 3.1 0.14 11.5 0.0 2.6 2 1 1 3 3 3 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 KPI35432.1 - 0.025 13.8 0.0 0.062 12.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 KPI35432.1 - 0.027 14.8 0.4 0.11 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 KPI35432.1 - 0.037 13.9 1.9 0.45 10.4 0.1 3.0 2 2 0 3 3 3 0 Adenylylsulphate kinase zf-C2H2_aberr PF17017.5 KPI35432.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger VPS53_C PF16854.5 KPI35432.1 - 0.19 11.6 2.3 0.39 10.6 0.2 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus ABC_tran PF00005.27 KPI35432.1 - 0.2 12.2 0.4 1.2 9.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Rho_Binding PF08912.11 KPI35432.1 - 0.4 11.5 3.7 0.22 12.3 0.8 2.0 2 0 0 2 2 2 0 Rho Binding AAA_23 PF13476.6 KPI35432.1 - 0.68 10.4 3.8 34 4.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain Swi3 PF07962.12 KPI35433.1 - 7.1e-29 99.6 0.1 1.3e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 CDC45 PF02724.14 KPI35434.1 - 1.8 6.7 9.1 2.8 6.1 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KPI35434.1 - 5.4 6.3 19.1 9.5 5.5 19.1 1.5 1 0 0 1 1 1 0 SDA1 Pterin_bind PF00809.22 KPI35436.1 - 7.1e-79 264.9 0.0 9.5e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KPI35436.1 - 1.5e-31 109.2 0.0 3e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Polyketide_cyc2 PF10604.9 KPI35439.1 - 4.6e-05 23.7 0.2 0.00015 22.0 0.0 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KPI35439.1 - 0.0033 17.6 0.0 0.0059 16.8 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_15 PF01793.16 KPI35440.1 - 3.7e-96 322.2 16.4 2.5e-95 319.5 16.4 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_18 PF00704.28 KPI35441.1 - 5.2e-14 52.7 0.0 7.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 KPI35442.1 - 7.3e-36 123.8 27.5 7.3e-36 123.8 27.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily SBDS_C PF09377.10 KPI35443.1 - 2.3e-42 143.7 0.0 3.1e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KPI35443.1 - 2.8e-31 107.5 0.0 5.7e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Mito_carr PF00153.27 KPI35444.1 - 3e-13 49.5 5.6 0.0034 17.3 0.0 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C15 PF01470.17 KPI35445.1 - 7.6e-10 39.3 0.0 0.0032 17.7 0.0 3.2 3 0 0 3 3 3 3 Pyroglutamyl peptidase Mtc PF03820.17 KPI35446.1 - 3.1e-121 404.2 0.1 3.5e-121 404.0 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Glyco_hydro_79C PF16862.5 KPI35447.1 - 1.9e-19 70.5 0.4 7.4e-19 68.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain RNA_pol_Rpb2_6 PF00562.28 KPI35448.1 - 1.2e-112 376.9 1.1 1.4e-112 376.6 1.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 KPI35448.1 - 4.4e-34 116.7 0.1 7.5e-34 116.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 MRNIP PF15749.5 KPI35448.1 - 0.00012 22.8 1.6 0.00018 22.2 1.6 1.3 1 0 0 1 1 1 1 MRN-interacting protein Citrate_ly_lig PF08218.11 KPI35448.1 - 0.13 12.0 0.1 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain MFS_1 PF07690.16 KPI35449.1 - 7.7e-10 38.2 15.6 7.7e-10 38.2 15.6 2.2 1 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35449.1 - 0.0031 16.4 0.1 0.0031 16.4 0.1 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter PAE PF03283.13 KPI35449.1 - 0.23 10.5 0.1 0.47 9.5 0.0 1.5 2 0 0 2 2 2 0 Pectinacetylesterase DPM3 PF08285.11 KPI35449.1 - 3.8 7.8 7.5 2.7 8.3 0.0 4.0 5 0 0 5 5 5 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2619 PF10942.8 KPI35449.1 - 7.2 6.8 8.3 0.16 12.1 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2619) Opi1 PF08618.10 KPI35450.1 - 9.8e-34 117.3 11.2 1.9e-28 99.9 0.2 2.7 1 1 1 3 3 3 2 Transcription factor Opi1 Pex14_N PF04695.13 KPI35450.1 - 0.043 14.5 10.2 0.31 11.7 3.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRP54 PF00448.22 KPI35451.1 - 5.9e-72 241.4 1.3 5.9e-72 241.4 1.3 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KPI35451.1 - 1.7e-31 108.8 4.5 1.7e-31 108.8 4.5 3.9 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KPI35451.1 - 1.8e-17 63.3 0.1 5.4e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_17 PF13207.6 KPI35451.1 - 4.7e-06 27.1 0.1 4.7e-06 27.1 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KPI35451.1 - 9.5e-06 25.8 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KPI35451.1 - 1.3e-05 24.9 1.2 4e-05 23.3 0.5 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KPI35451.1 - 0.00036 21.0 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KPI35451.1 - 0.001 19.1 0.3 0.0032 17.5 0.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit APS_kinase PF01583.20 KPI35451.1 - 0.0012 18.7 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 KPI35451.1 - 0.0025 17.9 0.0 0.0078 16.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KPI35451.1 - 0.0029 17.3 1.6 0.0038 17.0 0.2 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KPI35451.1 - 0.0046 16.3 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KPI35451.1 - 0.0047 17.5 0.0 0.014 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KPI35451.1 - 0.0047 16.3 0.4 0.0097 15.2 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase MobB PF03205.14 KPI35451.1 - 0.0049 16.8 0.1 0.08 12.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 KPI35451.1 - 0.0049 16.3 1.5 1.6 8.1 1.0 3.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 KPI35451.1 - 0.0052 16.5 0.8 0.033 13.9 0.1 2.5 2 0 0 2 2 2 1 Thymidylate kinase MMR_HSR1 PF01926.23 KPI35451.1 - 0.0072 16.4 0.9 0.36 10.9 0.2 3.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KPI35451.1 - 0.0091 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPI35451.1 - 0.021 15.1 1.0 0.05 13.9 0.2 2.1 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KPI35451.1 - 0.023 14.5 1.1 0.054 13.3 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KPI35451.1 - 0.024 15.0 0.2 0.071 13.4 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KPI35451.1 - 0.055 13.4 0.1 0.2 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KPI35451.1 - 0.061 12.8 0.5 0.23 10.9 0.0 2.2 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_25 PF13481.6 KPI35451.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPI35451.1 - 0.25 11.8 2.3 0.59 10.6 0.1 2.5 2 1 0 2 2 2 0 ABC transporter Peptidase_M57 PF12388.8 KPI35451.1 - 2.4 7.7 5.4 0.47 10.0 0.6 2.0 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Arv1 PF04161.13 KPI35452.1 - 1.3e-31 110.4 0.0 3.8e-30 105.6 0.0 2.0 2 0 0 2 2 2 2 Arv1-like family GFA PF04828.14 KPI35453.1 - 2.3e-17 63.1 0.2 2.3e-17 63.1 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HCV_NS5a_1a PF08300.13 KPI35453.1 - 0.097 12.8 0.8 0.097 12.8 0.8 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain TauD PF02668.16 KPI35455.1 - 4.9e-45 154.4 0.3 5.7e-45 154.2 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DCX PF03607.17 KPI35455.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Doublecortin SGL PF08450.12 KPI35456.1 - 3.5e-59 200.4 0.0 4.6e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KPI35456.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Arylesterase DUF839 PF05787.13 KPI35456.1 - 0.034 13.3 0.0 0.19 10.8 0.0 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF839) PD40 PF07676.12 KPI35456.1 - 0.048 13.6 0.6 0.4 10.7 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.11 KPI35456.1 - 0.17 12.2 0.3 13 6.4 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller Voldacs PF03517.13 KPI35457.1 - 9.1e-27 93.9 0.0 9.1e-27 93.9 0.0 2.7 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling PSD5 PF07637.11 KPI35459.1 - 2.3 8.6 4.3 5.6 7.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) RNase_T PF00929.24 KPI35460.1 - 5.2e-20 72.6 0.2 5.2e-20 72.6 0.2 1.6 2 0 0 2 2 2 1 Exonuclease MFS_1 PF07690.16 KPI35462.1 - 1.3e-17 63.8 48.6 2.5e-15 56.3 31.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI35462.1 - 1.4e-05 23.8 2.7 1.4e-05 23.8 2.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_2 PF00891.18 KPI35463.1 - 3.7e-19 68.9 0.0 7.7e-19 67.8 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Metal_resist PF13801.6 KPI35463.1 - 0.023 14.9 0.5 0.053 13.7 0.5 1.5 1 0 0 1 1 1 0 Heavy-metal resistance Methyltransf_PK PF05891.12 KPI35463.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Dimerisation2 PF16864.5 KPI35463.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain SIR2 PF02146.17 KPI35464.1 - 1.2e-26 93.7 0.0 5.4e-26 91.6 0.0 2.0 1 1 0 1 1 1 1 Sir2 family GFA PF04828.14 KPI35465.1 - 2.2e-18 66.4 0.1 3.4e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DIM1 PF02966.16 KPI35466.1 - 8.7e-70 232.7 0.5 9.9e-70 232.5 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KPI35466.1 - 0.00073 19.5 0.0 0.00092 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KPI35466.1 - 0.035 14.4 1.1 0.068 13.5 1.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like PIF1 PF05970.14 KPI35467.1 - 1.2e-58 199.0 2.2 1.7e-44 152.5 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KPI35467.1 - 9.7e-23 80.9 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI35467.1 - 3.3e-10 40.5 0.0 6.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPI35467.1 - 6.1e-06 26.5 0.0 1.8e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KPI35467.1 - 9.5e-05 22.2 0.1 0.00087 19.1 0.1 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KPI35467.1 - 0.00012 20.1 0.1 0.0011 17.1 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 KPI35467.1 - 0.00033 20.2 0.0 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KPI35467.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KPI35467.1 - 0.0036 17.7 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KPI35467.1 - 0.0099 15.3 0.3 0.03 13.8 0.1 1.8 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.22 KPI35467.1 - 0.018 15.5 0.0 0.067 13.6 0.0 2.1 1 1 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KPI35467.1 - 0.092 12.0 0.0 0.092 12.0 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KPI35467.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KPI35467.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KPI35467.1 - 0.13 12.2 0.3 1.5 8.8 0.3 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 KPI35467.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SH3_13 PF18335.1 KPI35467.1 - 0.14 12.0 1.0 0.39 10.6 0.1 2.2 3 0 0 3 3 2 0 ATP-dependent RecD-like DNA helicase SH3 domain EF-1_beta_acid PF10587.9 KPI35467.1 - 3.3 8.2 8.1 0.1 13.1 0.6 2.4 2 0 0 2 2 1 0 Eukaryotic elongation factor 1 beta central acidic region MFS_1 PF07690.16 KPI35468.1 - 1.1e-35 123.3 52.2 1.1e-35 123.3 52.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI35468.1 - 2.4e-13 49.4 29.2 2.4e-13 49.4 29.2 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KPI35468.1 - 5.4e-08 32.5 6.2 5.4e-08 32.5 6.2 3.5 3 1 1 4 4 4 1 Uncharacterised MFS-type transporter YbfB DUF1418 PF07214.12 KPI35468.1 - 0.28 11.1 2.6 1.9 8.4 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) AMP-binding PF00501.28 KPI35469.1 - 3.5e-70 236.7 0.0 4.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI35469.1 - 1.3e-12 48.5 0.0 3.1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hemerythrin PF01814.23 KPI35470.1 - 1.6e-09 38.4 1.1 2.2e-09 38.0 1.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.16 KPI35471.1 - 7.9e-51 173.0 28.3 7.9e-51 173.0 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35471.1 - 1.5e-12 47.1 8.6 1.5e-12 47.1 8.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI35471.1 - 1.1e-05 24.1 2.1 1.7e-05 23.4 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_kinase PF01513.21 KPI35472.1 - 2.8e-75 253.2 0.0 4.6e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KPI35472.1 - 0.036 13.7 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain MRC1 PF09444.10 KPI35472.1 - 0.45 11.0 6.5 4.3 7.8 0.2 2.8 3 0 0 3 3 3 0 MRC1-like domain Peptidase_M16_C PF05193.21 KPI35473.1 - 1.8e-55 187.8 0.0 7.3e-55 185.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPI35473.1 - 8.3e-40 136.2 0.0 2.1e-39 134.9 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.11 KPI35473.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase Voltage_CLC PF00654.20 KPI35474.1 - 2.1e-86 290.3 27.1 3.1e-86 289.8 27.1 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KPI35474.1 - 1.4e-11 44.6 0.0 3.7e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain Peptidase_S26 PF10502.9 KPI35475.1 - 5.8e-06 26.1 0.0 1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Tfb4 PF03850.14 KPI35476.1 - 6e-86 288.4 1.3 1.5e-53 182.1 0.0 2.6 2 1 0 2 2 2 2 Transcription factor Tfb4 RRM_1 PF00076.22 KPI35477.1 - 2.7e-57 190.5 0.0 1.9e-20 72.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI35477.1 - 6.9e-09 35.4 0.0 0.018 14.9 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KPI35477.1 - 2.6e-08 33.5 0.0 0.00014 21.5 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI35477.1 - 6.3e-05 22.9 0.3 0.25 11.4 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KPI35477.1 - 0.00019 21.5 0.1 0.4 10.8 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 KPI35477.1 - 0.00022 21.4 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain Cas_Cas2CT1978 PF09707.10 KPI35477.1 - 0.00043 20.3 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.11 KPI35477.1 - 0.015 15.3 0.1 0.47 10.5 0.1 2.6 3 0 0 3 3 3 0 RNA binding motif Abhydrolase_6 PF12697.7 KPI35478.1 - 3.7e-11 44.0 0.1 4.7e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family hNIFK_binding PF12196.8 KPI35479.1 - 4.1 7.0 8.5 6.3 6.4 1.2 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK adh_short PF00106.25 KPI35481.1 - 2.9e-08 33.4 0.0 6.8e-07 28.9 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 KPI35481.1 - 1.9e-06 27.5 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI35481.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Pribosyltran PF00156.27 KPI35482.1 - 2.1e-05 24.1 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DSPc PF00782.20 KPI35483.1 - 0.00014 21.7 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain tRNA_U5-meth_tr PF05958.11 KPI35484.1 - 2e-10 40.2 0.0 1.5e-07 30.8 0.0 3.2 3 1 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 KPI35484.1 - 1.3e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.13 KPI35484.1 - 5.1e-06 26.1 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KPI35484.1 - 0.0002 22.0 0.0 0.0004 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KPI35484.1 - 0.00025 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KPI35484.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI35484.1 - 0.022 15.4 0.0 0.049 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KPI35484.1 - 0.053 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 KPI35484.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HA2 PF04408.23 KPI35485.1 - 3.5e-24 85.2 0.1 3.5e-24 85.2 0.1 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPI35485.1 - 3.7e-20 72.1 0.0 7.8e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPI35485.1 - 7.5e-14 52.0 0.0 2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KPI35485.1 - 6e-10 39.3 1.9 1.2e-09 38.4 1.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KPI35485.1 - 9.9e-06 25.4 0.1 2.3e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPI35485.1 - 9e-05 22.8 0.0 0.00028 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI35485.1 - 0.0014 18.4 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPI35485.1 - 0.0014 17.7 0.0 0.0037 16.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KPI35485.1 - 0.0074 16.6 0.1 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KPI35485.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KPI35485.1 - 0.14 12.2 0.1 1.3 9.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPI35485.1 - 0.19 11.9 1.8 0.33 11.1 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 KPI35485.1 - 0.27 11.7 1.3 2 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPI35485.1 - 0.9 10.0 4.3 1.9 9.0 0.2 3.2 2 1 0 2 2 2 0 ABC transporter GMP_synt_C PF00958.22 KPI35486.1 - 3.7e-41 139.1 0.0 7e-41 138.2 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KPI35486.1 - 9.4e-37 126.6 0.0 1.7e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KPI35486.1 - 2.4e-10 39.9 0.1 3.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KPI35486.1 - 5.8e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KPI35486.1 - 0.0048 16.4 0.0 0.035 13.6 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KPI35486.1 - 0.0051 15.6 0.1 0.0099 14.7 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 KPI35486.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KPI35486.1 - 0.053 13.6 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KPI35486.1 - 0.077 12.3 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 KPI35486.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 PP-loop family TauD PF02668.16 KPI35487.1 - 2.6e-23 83.2 0.0 3.7e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EamA PF00892.20 KPI35488.1 - 6.7e-07 29.5 13.0 1e-06 29.0 13.0 1.3 1 0 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KPI35488.1 - 0.00065 19.7 2.1 0.00082 19.4 1.6 1.4 1 1 0 1 1 1 1 Putative transmembrane family 234 HET PF06985.11 KPI35489.1 - 1.4e-29 103.3 2.1 2.9e-29 102.3 2.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nipped-B_C PF12830.7 KPI35490.1 - 1.6e-27 96.7 5.2 6.2e-26 91.5 0.0 4.0 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cnd3 PF12719.7 KPI35490.1 - 4e-06 26.2 0.1 0.0078 15.4 0.0 3.7 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 KPI35490.1 - 0.00022 21.5 0.5 0.00095 19.4 0.5 2.3 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KPI35490.1 - 0.00032 19.4 0.1 0.0096 14.5 0.1 2.8 2 1 1 3 3 3 1 Adaptin N terminal region HEAT_2 PF13646.6 KPI35490.1 - 0.0023 18.3 0.2 7.9 6.9 0.1 5.1 3 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 KPI35490.1 - 0.0028 17.7 0.0 0.02 14.9 0.0 2.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KPI35490.1 - 0.0045 17.1 1.4 19 5.8 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat AT_hook PF02178.19 KPI35490.1 - 1.1 9.4 5.6 2.8 8.1 5.6 1.8 1 0 0 1 1 1 0 AT hook motif Vps16_N PF04841.13 KPI35492.1 - 2.4e-99 332.9 0.0 3.3e-99 332.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KPI35492.1 - 3.5e-85 285.9 0.0 5e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KPI35492.1 - 0.00095 19.4 0.0 0.28 11.5 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RCC1_2 PF13540.6 KPI35492.1 - 0.12 12.2 0.2 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat RINGv PF12906.7 KPI35493.1 - 5.6e-07 29.6 4.2 7.9e-07 29.1 0.8 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RanBP PF00641.18 KPI35493.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PhnA_Zn_Ribbon PF08274.12 KPI35493.1 - 0.26 11.3 0.8 0.44 10.5 0.8 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon PHD PF00628.29 KPI35493.1 - 0.4 10.6 4.3 0.14 12.1 0.9 1.9 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KPI35493.1 - 0.7 10.0 2.8 2.1 8.5 2.8 1.8 1 1 0 1 1 1 0 PHD-finger Glyco_hydro_2_C PF02836.17 KPI35494.1 - 2e-104 348.9 0.2 2.8e-104 348.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KPI35494.1 - 5e-66 222.8 0.0 2.3e-65 220.6 0.0 2.1 1 1 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KPI35494.1 - 9.1e-43 146.1 0.5 2.2e-42 144.9 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KPI35494.1 - 1.4e-16 60.8 0.0 5.4e-16 58.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KPI35494.1 - 0.058 14.1 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 UNC45-central PF11701.8 KPI35495.1 - 4.3e-38 130.7 2.8 1.2e-37 129.2 0.0 3.2 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KPI35495.1 - 0.028 14.5 12.7 2.3 8.4 0.1 6.9 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat PMC2NT PF08066.12 KPI35495.1 - 0.066 13.9 5.5 0.33 11.7 0.0 3.9 4 1 0 4 4 4 0 PMC2NT (NUC016) domain Proteasome PF00227.26 KPI35496.1 - 9.3e-57 191.6 0.0 9.8e-32 110.0 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KPI35496.1 - 4e-10 39.2 0.3 9.4e-10 38.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PIR PF00399.19 KPI35496.1 - 0.14 11.8 18.7 0.85 9.3 4.6 3.0 2 0 0 2 2 2 0 Yeast PIR protein repeat Helicase_C PF00271.31 KPI35497.1 - 5.6e-11 42.8 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 KPI35497.1 - 5.2e-10 39.1 0.2 1.1e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KPI35497.1 - 0.031 14.1 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 MatE PF01554.18 KPI35498.1 - 2.5e-24 85.7 7.3 2.5e-24 85.7 7.3 1.3 2 0 0 2 2 2 1 MatE Fasciclin PF02469.22 KPI35499.1 - 5.7e-38 130.0 0.5 7.4e-24 84.4 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain Herpes_US12 PF05363.12 KPI35500.1 - 3.8 8.3 5.0 4.6 8.0 0.2 2.9 3 0 0 3 3 3 0 Herpesvirus US12 family DNA_pol_lambd_f PF10391.9 KPI35501.1 - 0.12 12.2 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda FHA PF00498.26 KPI35502.1 - 3.2e-15 56.2 0.0 4.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 KPI35502.1 - 2.6e-12 46.2 4.9 4.7e-12 45.4 4.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KPI35502.1 - 5.8e-07 29.8 8.5 1.1e-06 28.8 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KPI35502.1 - 0.00012 22.3 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KPI35502.1 - 0.00028 20.7 8.7 0.00061 19.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI35502.1 - 0.0029 17.6 7.5 0.0059 16.6 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 KPI35502.1 - 0.0035 17.2 5.5 0.0064 16.4 5.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.6 KPI35502.1 - 0.011 15.5 8.2 0.023 14.5 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI35502.1 - 0.012 15.5 7.3 0.022 14.7 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KPI35502.1 - 0.038 14.0 3.7 0.17 12.0 3.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KPI35502.1 - 0.05 13.9 7.7 0.15 12.4 7.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 KPI35502.1 - 1.4 9.3 5.7 2.5 8.4 5.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF5327 PF17261.2 KPI35504.1 - 0.016 15.9 3.6 0.078 13.7 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Helo_like_N PF17111.5 KPI35504.1 - 0.027 13.8 0.6 0.042 13.2 0.6 1.4 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins HTH_AraC PF00165.23 KPI35504.1 - 0.14 12.3 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family FAM25 PF15825.5 KPI35504.1 - 0.69 10.3 4.1 2.1 8.7 0.6 2.4 1 1 1 2 2 2 0 FAM25 family HEAT_2 PF13646.6 KPI35505.1 - 3.1e-29 101.2 3.5 2.8e-14 53.3 0.0 3.6 2 2 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KPI35505.1 - 2e-20 71.3 1.0 0.0067 17.0 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KPI35505.1 - 1.9e-08 33.8 3.8 0.22 11.9 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KPI35505.1 - 2.6e-07 31.0 8.4 0.017 15.6 0.0 5.3 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 KPI35505.1 - 0.00081 19.4 0.8 1.5 9.0 0.0 3.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 KPI35505.1 - 0.013 15.7 0.1 1.3 9.3 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.13 KPI35505.1 - 0.11 12.9 0.9 30 5.2 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain DUF3385 PF11865.8 KPI35505.1 - 0.18 11.7 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) F-box-like PF12937.7 KPI35507.1 - 0.01 15.7 0.4 0.018 14.9 0.4 1.4 1 0 0 1 1 1 0 F-box-like Aa_trans PF01490.18 KPI35508.1 - 3.5e-50 170.9 34.2 4.2e-50 170.7 34.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4604 PF15377.6 KPI35510.1 - 1.7e-22 80.7 19.4 1.9e-22 80.5 19.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2070 PF09843.9 KPI35510.1 - 0.53 8.5 1.1 0.69 8.1 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MatE PF01554.18 KPI35511.1 - 8.4e-35 119.8 9.6 1.1e-34 119.4 9.6 1.1 1 0 0 1 1 1 1 MatE HAD PF12710.7 KPI35512.1 - 1.8e-16 61.1 0.0 3.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KPI35512.1 - 0.0081 15.6 0.0 0.057 12.8 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 KPI35512.1 - 0.013 15.8 0.4 0.94 9.7 0.0 3.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KPI35512.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Nucleoporin_FG PF13634.6 KPI35513.1 - 8.1e-05 23.4 9.1 8.1e-05 23.4 9.1 1.8 2 0 0 2 2 2 1 Nucleoporin FG repeat region MIP PF00230.20 KPI35514.1 - 1.5e-43 149.2 22.6 1.8e-43 148.8 22.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 KPI35517.1 - 2.6e-29 102.4 0.0 3.8e-26 92.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI35517.1 - 2.7e-20 72.8 0.0 3.8e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI35517.1 - 0.00029 20.8 0.1 0.00057 19.9 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI35517.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPI35517.1 - 0.0035 16.4 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPI35517.1 - 0.036 13.4 0.5 0.072 12.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPI35517.1 - 0.038 12.8 0.0 0.4 9.4 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KPI35517.1 - 0.045 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.24 KPI35518.1 - 2.1e-99 333.4 12.5 2.4e-99 333.2 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35518.1 - 1.2e-19 70.5 29.0 1.2e-19 70.5 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Menin PF05053.13 KPI35520.1 - 2.7 6.2 6.1 3 6.1 6.1 1.2 1 0 0 1 1 1 0 Menin She9_MDM33 PF05546.11 KPI35521.1 - 8.7e-85 283.5 6.5 8.7e-85 283.5 6.5 1.8 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.20 KPI35521.1 - 0.14 11.9 0.9 0.29 10.9 0.9 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Uso1_p115_C PF04871.13 KPI35521.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.6 5 0 0 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region G-patch PF01585.23 KPI35522.1 - 4.4e-07 29.7 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 G-patch domain Cep57_CLD_2 PF14197.6 KPI35523.1 - 1.2 9.3 5.8 1.9 8.6 4.5 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Adaptin_binding PF10199.9 KPI35524.1 - 2.2e-06 28.3 0.8 5.6e-06 27.0 0.8 1.6 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 hGDE_central PF14702.6 KPI35524.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Rieske PF00355.26 KPI35525.1 - 5.5e-11 42.3 0.0 9.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KPI35525.1 - 1.3e-10 41.6 0.4 3.3e-10 40.3 0.4 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF1353 PF07087.11 KPI35525.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) DUF202 PF02656.15 KPI35526.1 - 1.3e-18 67.1 1.4 8.8e-18 64.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PMP22_Claudin PF00822.20 KPI35526.1 - 0.035 14.0 0.7 0.048 13.5 0.7 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family PhoLip_ATPase_C PF16212.5 KPI35526.1 - 0.036 13.8 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal MFS_1 PF07690.16 KPI35527.1 - 4e-32 111.5 58.4 8.6e-32 110.4 58.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI35527.1 - 4e-07 28.8 23.6 6.7e-07 28.1 23.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Myc_N PF01056.18 KPI35527.1 - 1.4 8.8 4.6 0.58 10.0 2.1 1.4 1 1 0 1 1 1 0 Myc amino-terminal region GTP_EFTU PF00009.27 KPI35529.1 - 2.3e-18 66.4 0.0 5e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KPI35529.1 - 1.6e-09 38.0 1.0 1.8e-08 34.6 0.8 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KPI35529.1 - 8.6e-05 22.8 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KPI35529.1 - 0.028 14.5 0.1 0.093 12.8 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KPI35529.1 - 0.048 13.4 0.1 1.4 8.7 0.1 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KPI35529.1 - 0.063 13.2 0.9 3.6 7.5 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase FAD_oxidored PF12831.7 KPI35530.1 - 3.6e-99 333.0 0.0 4.4e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI35530.1 - 7e-05 22.1 1.0 0.0007 18.8 1.3 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI35530.1 - 0.00038 20.6 0.9 0.0014 18.8 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPI35530.1 - 0.012 14.8 0.9 0.042 12.9 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KPI35530.1 - 0.021 14.1 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI35530.1 - 0.098 11.9 0.5 0.3 10.3 0.5 1.7 1 1 0 1 1 1 0 FAD binding domain WD40 PF00400.32 KPI35531.1 - 4e-28 97.1 4.6 2.8e-05 24.8 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI35531.1 - 1.2e-07 31.9 0.0 0.091 13.1 0.0 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI35531.1 - 0.0053 15.8 0.0 0.31 9.9 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KPI35531.1 - 0.056 13.5 0.0 6.9 6.8 0.0 3.8 4 2 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Prot_ATP_ID_OB PF16450.5 KPI35531.1 - 0.084 12.8 0.3 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Cupin_2 PF07883.11 KPI35532.1 - 2.7e-07 30.2 1.1 7.4e-07 28.8 0.1 2.2 3 1 0 3 3 3 1 Cupin domain Cupin_1 PF00190.22 KPI35532.1 - 0.00024 20.8 0.1 0.00033 20.3 0.1 1.2 1 0 0 1 1 1 1 Cupin Helo_like_N PF17111.5 KPI35533.1 - 9.9e-06 25.1 2.0 1e-05 25.0 0.6 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Abhydrolase_6 PF12697.7 KPI35534.1 - 2.9e-07 31.3 0.3 0.00018 22.2 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI35534.1 - 0.00022 20.8 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KPI35534.1 - 0.00027 20.7 0.1 0.0019 17.9 0.1 2.0 1 1 0 1 1 1 1 Putative esterase LRR_8 PF13855.6 KPI35536.1 - 1.1e-12 47.5 24.1 2.4e-05 24.0 2.9 5.4 2 2 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KPI35536.1 - 1.8e-10 40.6 10.4 1.3e-05 24.8 1.1 3.5 2 1 2 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 KPI35536.1 - 6e-07 29.7 32.0 0.00079 19.8 1.1 6.9 7 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPI35536.1 - 6.5e-05 22.7 14.0 5.2 7.4 0.1 7.8 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 KPI35536.1 - 0.13 12.9 24.0 2.9 8.8 0.9 7.9 6 2 1 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 KPI35537.1 - 8.1e-38 130.3 0.0 7e-37 127.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI35537.1 - 1.7e-12 47.2 0.0 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI35537.1 - 0.01 14.6 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sec1 PF00995.23 KPI35538.1 - 6.8e-114 382.2 0.0 8e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Mucin_bdg PF03272.13 KPI35538.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module MFS_1 PF07690.16 KPI35539.1 - 7.9e-37 127.0 27.9 7.9e-37 127.0 27.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily LapA_dom PF06305.11 KPI35539.1 - 0.19 11.6 3.7 0.15 11.9 0.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LSM PF01423.22 KPI35540.1 - 8.3e-16 57.4 0.1 1.1e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPI35540.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.9 KPI35540.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Phage tail tube protein LSM PF01423.22 KPI35542.1 - 1.3e-18 66.4 0.1 1.6e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.17 KPI35545.1 - 5.4e-27 95.0 0.0 8.9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SOG2 PF10428.9 KPI35545.1 - 0.47 9.6 2.3 0.59 9.3 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Actin PF00022.19 KPI35546.1 - 5.5e-89 298.6 0.0 3e-55 187.5 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KPI35546.1 - 0.1 11.4 0.0 3 6.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein HXXSHH PF07586.11 KPI35547.1 - 0.008 15.8 0.9 0.016 14.8 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) DPM3 PF08285.11 KPI35548.1 - 2.7e-29 101.2 0.0 3.1e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1624 PF07786.12 KPI35548.1 - 0.089 12.3 0.4 0.099 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) p450 PF00067.22 KPI35549.1 - 1.5e-60 205.3 0.0 2.4e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KPI35550.1 - 6.9e-86 288.9 23.3 8.1e-86 288.7 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35550.1 - 1.1e-30 106.8 27.2 1.1e-30 106.8 27.2 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily PGP_phosphatase PF09419.10 KPI35551.1 - 3.3e-42 143.9 0.0 9.4e-24 83.9 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KPI35551.1 - 9.4e-07 28.8 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KPI35551.1 - 0.0015 18.8 0.2 0.085 13.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase AAA_lid_2 PF17863.1 KPI35554.1 - 4.2e-07 29.7 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain PrpF PF04303.13 KPI35555.1 - 9.7e-90 301.2 0.0 1.2e-89 300.9 0.0 1.0 1 0 0 1 1 1 1 PrpF protein MFS_1 PF07690.16 KPI35556.1 - 6.2e-21 74.7 45.0 7.9e-12 44.8 20.5 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily PBP PF01161.20 KPI35557.1 - 5.1e-06 26.8 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Bac_rhamnosid6H PF17389.2 KPI35558.1 - 1.5e-11 44.1 0.1 7.4e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid PF05592.11 KPI35558.1 - 0.017 15.1 0.1 0.14 12.2 0.1 2.4 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF608 PF04685.13 KPI35558.1 - 0.029 13.6 0.2 0.045 12.9 0.2 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 KPI35558.1 - 0.11 11.3 0.2 0.17 10.7 0.2 1.1 1 0 0 1 1 1 0 Trehalase Abhydrolase_3 PF07859.13 KPI35559.1 - 3.8e-49 167.4 0.0 5.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI35559.1 - 7.1e-07 28.5 0.1 2.2e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family vWA-TerF-like PF10138.9 KPI35559.1 - 6.4e-05 23.2 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Peptidase_S9 PF00326.21 KPI35559.1 - 8.7e-05 22.1 0.0 0.0026 17.3 0.0 2.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KPI35559.1 - 0.013 14.2 0.0 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 KPI35559.1 - 0.031 13.1 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase DLH PF01738.18 KPI35559.1 - 0.042 13.4 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family VWA PF00092.28 KPI35559.1 - 0.17 12.1 0.2 0.53 10.5 0.2 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Cullin_binding PF03556.15 KPI35560.1 - 1.4e-31 109.5 2.9 3e-31 108.3 2.5 1.7 2 0 0 2 2 2 1 Cullin binding SH3_9 PF14604.6 KPI35561.1 - 7.3e-05 22.5 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI35561.1 - 0.0054 16.4 0.5 0.012 15.3 0.5 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI35561.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Zn_clus PF00172.18 KPI35561.1 - 1.3 9.2 4.1 3 8.0 4.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Alb1 PF09135.11 KPI35562.1 - 8.8e-12 45.8 15.6 3e-10 40.9 15.6 2.5 1 1 0 1 1 1 1 Alb1 zf-RING_5 PF14634.6 KPI35564.1 - 3.2e-07 30.2 10.3 3.2e-07 30.2 10.3 2.0 3 0 0 3 3 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KPI35564.1 - 3.1e-06 26.8 3.1 2.6e-05 23.9 0.6 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 KPI35564.1 - 1.3e-05 25.4 11.3 1.3e-05 25.4 11.3 2.0 2 0 0 2 2 1 1 Ring finger domain AAA_13 PF13166.6 KPI35564.1 - 0.00029 19.7 11.5 0.0004 19.2 11.5 1.1 1 0 0 1 1 1 1 AAA domain zf-C3HC4_2 PF13923.6 KPI35564.1 - 0.00036 20.3 8.9 0.00036 20.3 8.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI35564.1 - 0.00061 19.6 9.6 0.0016 18.3 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 KPI35564.1 - 0.00062 20.2 27.8 0.046 14.2 5.4 3.9 1 1 2 3 3 3 2 Cell division protein ZapB bZIP_1 PF00170.21 KPI35564.1 - 0.00092 19.3 20.5 0.02 15.0 0.3 5.5 1 1 5 7 7 7 2 bZIP transcription factor zf-rbx1 PF12678.7 KPI35564.1 - 0.00093 19.4 8.8 0.00093 19.4 8.8 2.1 3 0 0 3 3 1 1 RING-H2 zinc finger domain CCDC144C PF14915.6 KPI35564.1 - 0.00097 18.3 25.1 0.0016 17.6 25.1 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region KASH_CCD PF14662.6 KPI35564.1 - 0.0017 18.2 26.9 0.36 10.6 5.6 3.1 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH Yuri_gagarin PF15934.5 KPI35564.1 - 0.0019 18.1 9.4 0.0019 18.1 9.4 2.2 1 1 1 2 2 2 1 Yuri gagarin zf-RING_UBOX PF13445.6 KPI35564.1 - 0.0023 17.9 8.7 0.01 15.9 6.5 2.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPI35564.1 - 0.004 17.0 8.7 0.013 15.4 8.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Filament PF00038.21 KPI35564.1 - 0.0059 16.2 23.7 0.022 14.3 16.0 2.1 1 1 1 2 2 2 1 Intermediate filament protein HAP1_N PF04849.13 KPI35564.1 - 0.0081 15.4 26.6 0.14 11.3 10.2 2.4 1 1 1 2 2 2 2 HAP1 N-terminal conserved region PRKG1_interact PF15898.5 KPI35564.1 - 0.0097 16.8 21.6 0.75 10.7 15.9 3.5 2 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 KPI35564.1 - 0.011 15.8 2.4 0.011 15.8 2.4 3.8 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 DUF812 PF05667.11 KPI35564.1 - 0.012 14.5 21.3 0.017 14.1 21.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 KPI35564.1 - 0.018 15.2 19.7 0.079 13.1 10.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KPI35564.1 - 0.019 15.0 17.3 0.97 9.5 3.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KPI35564.1 - 0.021 14.9 28.0 0.51 10.4 13.9 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 KPI35564.1 - 0.024 13.3 16.4 0.015 13.9 5.0 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A CALCOCO1 PF07888.11 KPI35564.1 - 0.036 12.9 29.9 0.032 13.1 14.9 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 KPI35564.1 - 0.04 14.6 19.9 1.8 9.2 4.6 3.7 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 KPI35564.1 - 0.044 14.0 36.9 1.3 9.2 13.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zf-ANAPC11 PF12861.7 KPI35564.1 - 0.058 13.4 6.4 0.12 12.5 6.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_MLP1_2 PF07926.12 KPI35564.1 - 0.061 13.4 30.9 0.076 13.1 8.4 3.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Tektin PF03148.14 KPI35564.1 - 0.073 11.8 23.5 0.26 10.0 9.1 2.3 1 1 1 2 2 2 0 Tektin family bZIP_2 PF07716.15 KPI35564.1 - 0.099 12.7 23.5 1.3 9.1 1.4 5.9 5 1 1 6 6 6 0 Basic region leucine zipper ADIP PF11559.8 KPI35564.1 - 0.1 12.7 33.1 0.29 11.2 12.8 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HlyD_2 PF12700.7 KPI35564.1 - 0.12 11.1 8.6 0.16 10.7 8.6 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Mod_r PF07200.13 KPI35564.1 - 0.14 12.3 27.5 0.2 11.8 2.9 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HrpB7 PF09486.10 KPI35564.1 - 0.18 12.2 18.8 1.7 9.0 7.9 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 KPI35564.1 - 0.22 11.9 22.9 1.7 9.0 9.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 KPI35564.1 - 0.23 12.0 32.0 2.2 8.8 12.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region EzrA PF06160.12 KPI35564.1 - 0.24 9.5 18.1 0.074 11.2 1.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FUSC PF04632.12 KPI35564.1 - 0.29 9.6 17.4 1.4 7.4 11.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Spc7 PF08317.11 KPI35564.1 - 0.35 9.7 28.9 5.6 5.7 16.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein JIP_LZII PF16471.5 KPI35564.1 - 0.47 10.7 22.2 1.1 9.4 0.6 3.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II SHE3 PF17078.5 KPI35564.1 - 0.53 10.0 26.0 0.058 13.1 18.0 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 PikAIV_N PF18605.1 KPI35564.1 - 0.56 9.8 13.2 0.25 10.9 3.4 3.6 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Jnk-SapK_ap_N PF09744.9 KPI35564.1 - 0.71 10.1 31.6 1.8 8.8 8.7 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KPI35564.1 - 0.73 10.2 18.8 7.2 6.9 6.2 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) GAS PF13851.6 KPI35564.1 - 0.75 9.1 25.7 0.2 11.0 18.6 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KPI35564.1 - 0.83 9.9 11.1 1.4 9.2 2.5 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 KPI35564.1 - 1.1 10.0 29.2 0.11 13.1 10.3 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4472 PF14739.6 KPI35564.1 - 1.1 10.1 24.4 4.7 8.0 7.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF4407 PF14362.6 KPI35564.1 - 1.2 8.5 21.3 3.1 7.1 6.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KPI35564.1 - 1.5 9.1 24.3 1 9.6 1.2 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FlgN PF05130.12 KPI35564.1 - 1.5 9.3 24.2 3.7 8.0 15.1 2.9 1 1 2 3 3 3 0 FlgN protein Spc24 PF08286.11 KPI35564.1 - 2.1 8.6 20.0 0.34 11.2 0.2 3.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 HALZ PF02183.18 KPI35564.1 - 2.8 8.2 31.8 2.6 8.3 0.6 6.1 4 2 2 6 6 6 0 Homeobox associated leucine zipper KIAA1430 PF13879.6 KPI35564.1 - 3 8.7 12.1 11 6.8 11.5 2.2 1 1 1 2 2 2 0 KIAA1430 homologue Lebercilin PF15619.6 KPI35564.1 - 3.5 7.3 32.0 1.4 8.6 2.3 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-C3HC4 PF00097.25 KPI35564.1 - 3.6 7.5 18.3 0.63 10.0 12.3 2.8 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Golgin_A5 PF09787.9 KPI35564.1 - 3.8 6.9 28.3 11 5.4 28.1 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 DivIC PF04977.15 KPI35564.1 - 3.8 7.3 30.7 0.83 9.5 1.3 5.0 1 1 4 5 5 5 0 Septum formation initiator ERM PF00769.19 KPI35564.1 - 4.1 7.2 26.4 8.1 6.2 26.4 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 KPI35564.1 - 4.3 7.6 18.7 5.7 7.2 2.4 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 KPI35564.1 - 4.4 7.4 30.1 0.2 11.8 4.0 3.2 1 1 2 3 3 3 0 Tropomyosin like DUF3450 PF11932.8 KPI35564.1 - 4.8 6.4 24.3 4.6 6.5 8.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 KPI35564.1 - 5.2 7.2 34.1 0.22 11.6 11.0 4.5 1 1 4 5 5 5 0 Centrosome localisation domain of PPC89 Prominin PF05478.11 KPI35564.1 - 5.7 4.8 17.6 3.8 5.3 5.1 2.1 1 1 1 2 2 2 0 Prominin Cep57_MT_bd PF06657.13 KPI35564.1 - 6.6 7.3 21.2 13 6.3 2.6 3.9 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Rootletin PF15035.6 KPI35564.1 - 7.2 6.6 31.1 11 6.0 16.8 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.14 KPI35564.1 - 9.1 6.1 19.5 2.2 8.0 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 KPI35564.1 - 9.4 3.6 26.5 0.74 7.3 17.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 KPI35564.1 - 9.7 6.3 26.4 5.8 7.0 4.4 4.3 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding Asparaginase_2 PF01112.18 KPI35565.1 - 1.1e-39 136.3 6.2 3.1e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase DUF3987 PF13148.6 KPI35565.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Collagen PF01391.18 KPI35566.1 - 2.6e-12 46.3 55.9 2.5e-07 30.3 26.1 3.3 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) WSC PF01822.19 KPI35566.1 - 0.0015 18.6 9.6 0.0023 18.1 9.6 1.3 1 0 0 1 1 1 1 WSC domain CBFD_NFYB_HMF PF00808.23 KPI35567.1 - 3.4e-11 43.3 0.3 6e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPI35567.1 - 0.0052 17.1 0.2 0.0052 17.1 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KPI35567.1 - 0.1 12.6 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Abhydrolase_6 PF12697.7 KPI35568.1 - 5.5e-17 63.1 0.7 6.7e-17 62.8 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.8 KPI35568.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Hydrolase_4 PF12146.8 KPI35568.1 - 0.043 13.1 0.0 1.6 7.9 0.0 2.7 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Amidase PF01425.21 KPI35569.1 - 5.6e-59 200.3 0.9 1.6e-57 195.5 0.1 2.0 1 1 1 2 2 2 2 Amidase ORMDL PF04061.14 KPI35570.1 - 7.7e-55 184.4 2.0 1.1e-54 183.9 2.0 1.2 1 0 0 1 1 1 1 ORMDL family UAA PF08449.11 KPI35571.1 - 7.4e-79 265.1 4.5 9.4e-79 264.7 4.5 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KPI35571.1 - 0.0084 15.3 0.9 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 KPI35571.1 - 0.073 13.2 31.6 0.57 10.4 6.7 3.8 2 2 1 3 3 3 0 EamA-like transporter family TPT PF03151.16 KPI35571.1 - 0.17 11.2 9.0 0.83 8.9 1.2 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family MFS_1 PF07690.16 KPI35572.1 - 1.5e-26 93.2 18.5 1.5e-26 93.2 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35572.1 - 1.7e-08 33.8 1.0 1.7e-08 33.8 1.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI35572.1 - 5.7e-07 28.3 1.3 5.7e-07 28.3 1.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sds3 PF08598.11 KPI35573.1 - 6.6e-26 91.7 15.6 2.2e-25 90.0 15.6 1.8 1 1 0 1 1 1 1 Sds3-like AXE1 PF05448.12 KPI35574.1 - 7.4e-14 51.1 0.0 9.8e-07 27.7 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KPI35574.1 - 6.9e-09 35.7 0.0 1.6e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KPI35574.1 - 1.3e-08 35.8 0.0 1.6e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI35574.1 - 2.1e-08 33.9 0.0 4.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KPI35574.1 - 3.7e-08 33.3 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KPI35574.1 - 1.3e-05 25.2 0.0 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KPI35574.1 - 9.5e-05 21.8 0.0 0.097 11.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KPI35574.1 - 0.035 13.7 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family HLH PF00010.26 KPI35575.1 - 2.2e-13 49.9 0.2 5.5e-13 48.7 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain EMC3_TMCO1 PF01956.16 KPI35576.1 - 1.5e-55 187.6 0.0 1.5e-55 187.6 0.0 1.4 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Nop14 PF04147.12 KPI35578.1 - 1.2e-258 860.9 25.2 1.5e-258 860.6 25.2 1.1 1 0 0 1 1 1 1 Nop14-like family SMP_LBD PF17047.5 KPI35579.1 - 9.8e-23 80.5 0.1 4.7e-18 65.3 0.2 2.2 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KPI35579.1 - 1.8e-18 66.7 0.0 1.4e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain Na_Ca_ex PF01699.24 KPI35580.1 - 6.6e-28 97.6 19.5 1.3e-17 64.1 7.6 3.1 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF3169 PF11368.8 KPI35580.1 - 0.65 9.5 5.2 0.22 11.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Form_Nir_trans PF01226.17 KPI35581.1 - 1.1e-74 250.7 18.4 1.3e-74 250.5 18.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter HET PF06985.11 KPI35582.1 - 2.2e-22 80.0 0.1 1.7e-21 77.1 0.0 2.1 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Gly_kinase PF02595.15 KPI35583.1 - 2.9e-127 424.7 3.2 3.3e-127 424.5 3.2 1.0 1 0 0 1 1 1 1 Glycerate kinase family PucR PF07905.11 KPI35583.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ureidogly_lyase PF04115.12 KPI35584.1 - 6.9e-50 169.4 0.0 8.2e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase HA2 PF04408.23 KPI35585.1 - 1.8e-20 73.2 2.3 1.4e-19 70.3 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPI35585.1 - 2e-16 60.1 0.0 1.1e-15 57.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPI35585.1 - 2.1e-12 47.3 0.0 6.2e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI35585.1 - 1.5e-07 31.4 0.1 3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPI35585.1 - 1.8e-05 25.0 0.1 5e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI35585.1 - 8e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KPI35585.1 - 0.00013 21.4 0.0 0.00032 20.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KPI35585.1 - 0.00061 20.1 0.1 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPI35585.1 - 0.0012 17.9 0.0 0.0033 16.5 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KPI35585.1 - 0.0012 18.5 0.4 0.0037 16.9 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KPI35585.1 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_14 PF13173.6 KPI35585.1 - 0.0045 17.0 0.4 0.029 14.4 0.4 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KPI35585.1 - 0.01 15.9 1.4 3.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KPI35585.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC Microtub_bd PF16796.5 KPI35585.1 - 0.023 14.6 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding AAA_25 PF13481.6 KPI35585.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPI35585.1 - 0.14 12.6 1.3 0.3 11.6 0.0 2.3 3 0 0 3 3 1 0 ABC transporter cobW PF02492.19 KPI35585.1 - 0.24 11.0 0.8 0.9 9.1 0.0 2.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KPI35585.1 - 0.4 10.6 2.3 1.3 8.9 0.2 2.5 3 0 0 3 3 3 0 NACHT domain Peptidase_M14 PF00246.24 KPI35586.1 - 3.9e-71 240.2 0.0 7.7e-71 239.2 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KPI35586.1 - 2.2e-05 24.8 0.1 4.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Prefoldin_2 PF01920.20 KPI35587.1 - 4.5e-22 78.0 4.5 6.2e-22 77.6 4.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit MutS_IV PF05190.18 KPI35587.1 - 0.0024 18.2 0.6 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV Spuma_A9PTase PF03539.14 KPI35587.1 - 0.03 14.5 0.6 0.048 13.8 0.1 1.5 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) SMC_ScpA PF02616.14 KPI35587.1 - 0.06 13.2 0.9 0.13 12.1 0.8 1.6 1 1 0 1 1 1 0 Segregation and condensation protein ScpA Com_YlbF PF06133.11 KPI35587.1 - 0.083 13.5 5.6 0.27 11.8 0.4 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FlxA PF14282.6 KPI35587.1 - 0.19 11.7 6.6 0.83 9.7 2.0 2.2 2 0 0 2 2 2 0 FlxA-like protein Filo_VP35 PF02097.15 KPI35587.1 - 0.22 10.5 0.8 23 3.9 0.1 2.8 1 1 1 3 3 3 0 Filoviridae VP35 Prefoldin PF02996.17 KPI35587.1 - 0.27 11.1 8.0 0.94 9.4 4.1 2.4 2 1 0 2 2 2 0 Prefoldin subunit DUF2205 PF10224.9 KPI35587.1 - 0.34 10.9 3.7 0.17 11.9 1.0 1.8 2 0 0 2 2 2 0 Short coiled-coil protein SlyX PF04102.12 KPI35587.1 - 0.85 10.3 4.2 3.9 8.2 1.3 2.7 3 0 0 3 3 3 0 SlyX DUF3450 PF11932.8 KPI35587.1 - 1.3 8.2 7.4 1.5 8.0 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 KPI35587.1 - 1.4 9.2 6.1 1.3 9.3 1.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fungal_trans PF04082.18 KPI35588.1 - 4.8e-11 42.2 1.8 6.5e-11 41.8 0.9 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF917 PF06032.12 KPI35589.1 - 1.1e-115 386.2 2.4 2e-115 385.4 0.7 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KPI35589.1 - 4.9e-09 35.9 1.1 0.00021 20.6 0.2 2.3 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase Scm3 PF10384.9 KPI35590.1 - 1e-17 63.6 0.3 4.1e-17 61.7 0.3 2.2 1 0 0 1 1 1 1 Centromere protein Scm3 zf-C2H2_4 PF13894.6 KPI35590.1 - 4e-05 24.1 3.1 1.1 10.3 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI35590.1 - 0.051 14.1 2.0 41 4.9 0.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF773 PF05600.12 KPI35590.1 - 0.28 9.9 2.4 0.48 9.1 2.4 1.3 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Cupin_1 PF00190.22 KPI35591.1 - 4.9e-07 29.5 0.1 6.2e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPI35591.1 - 1.2e-05 24.9 0.3 6e-05 22.7 0.3 2.0 1 1 0 1 1 1 1 Cupin domain MOSC PF03473.17 KPI35592.1 - 2e-23 82.8 0.0 3.2e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPI35592.1 - 6.2e-18 64.8 0.0 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain HET PF06985.11 KPI35593.1 - 2.1e-06 28.1 2.5 1.9e-05 25.0 1.1 2.8 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 KPI35594.1 - 4e-05 22.6 3.4 0.0018 17.2 3.4 2.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain SAF PF08666.12 KPI35595.1 - 0.13 12.9 0.1 0.3 11.7 0.1 1.7 1 0 0 1 1 1 0 SAF domain TRI12 PF06609.13 KPI35596.1 - 2e-36 125.6 23.7 2.4e-36 125.3 23.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI35596.1 - 8.3e-23 80.9 43.5 8.3e-23 80.9 43.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35596.1 - 2.4e-12 46.5 25.8 1e-08 34.5 10.1 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_15 PF00723.21 KPI35597.1 - 9e-76 255.4 0.1 1.1e-75 255.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KPI35597.1 - 2.6e-09 36.9 0.1 7.4e-09 35.4 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain Jun PF03957.13 KPI35597.1 - 0.16 11.8 5.3 2.7 7.8 1.9 2.3 2 0 0 2 2 2 0 Jun-like transcription factor RICH PF05062.12 KPI35598.1 - 0.17 12.3 0.0 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 RICH domain Shikimate_dh_N PF08501.11 KPI35599.1 - 1.1e-17 64.0 0.0 2.3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 KPI35599.1 - 6.6e-17 62.5 0.0 1.1e-16 61.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KPI35599.1 - 1.4e-12 48.0 0.0 1.6e-11 44.5 0.0 2.2 1 1 1 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.20 KPI35599.1 - 4.2e-06 26.9 0.0 9.9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI35599.1 - 0.022 15.0 0.0 0.64 10.3 0.1 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L7Ae PF01248.26 KPI35599.1 - 0.032 14.0 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ThiF PF00899.21 KPI35599.1 - 0.14 11.4 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 ThiF family SnoaL_4 PF13577.6 KPI35600.1 - 2e-07 31.2 1.1 2.7e-07 30.7 1.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPI35600.1 - 0.024 15.0 0.3 0.04 14.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF2235 PF09994.9 KPI35601.1 - 8.5e-56 189.4 0.0 2.6e-34 118.9 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) APG6 PF04111.12 KPI35602.1 - 2.8e-66 222.9 0.0 6.2e-66 221.8 0.0 1.6 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 KPI35602.1 - 7.9e-32 110.6 20.3 1.2e-31 110.0 20.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region ATG16 PF08614.11 KPI35602.1 - 0.0041 17.4 13.8 0.012 15.8 13.8 1.8 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FPP PF05911.11 KPI35602.1 - 0.011 14.0 7.5 0.013 13.7 7.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil V_ATPase_I PF01496.19 KPI35602.1 - 0.012 13.6 3.0 0.016 13.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 KPI35602.1 - 0.16 11.8 9.2 0.29 10.9 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KPI35602.1 - 0.75 8.6 12.3 1.3 7.8 12.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KPI35602.1 - 2.1 8.4 14.5 6 6.9 14.5 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KPI35602.1 - 2.6 8.3 15.0 17 5.7 14.9 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 KPI35602.1 - 2.6 6.5 4.7 4.7 5.6 4.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cnn_1N PF07989.11 KPI35602.1 - 7.6 6.8 14.6 13 6.0 2.5 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 adh_short PF00106.25 KPI35603.1 - 1.4e-26 93.2 0.0 1.8e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35603.1 - 4.8e-13 49.2 0.0 6.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35603.1 - 8.5e-06 25.8 0.1 3.4e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 KR domain S4 PF01479.25 KPI35604.1 - 3.3e-10 39.5 0.1 5.3e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KPI35604.1 - 1.9e-09 38.3 0.8 1.9e-09 38.3 0.8 1.8 2 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Aldose_epim PF01263.20 KPI35605.1 - 4.2e-52 177.3 0.2 5.8e-52 176.9 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Rdx PF10262.9 KPI35607.1 - 1e-29 102.5 0.3 2.6e-29 101.2 0.3 1.7 1 1 0 1 1 1 1 Rdx family p450 PF00067.22 KPI35608.1 - 2.1e-46 158.6 0.0 2.6e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3856 PF12968.7 KPI35608.1 - 0.09 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 KPI35610.1 - 1.8e-06 27.6 11.0 0.0036 17.3 1.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4470 PF14737.6 KPI35610.1 - 9e-06 25.8 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_1 PF00515.28 KPI35610.1 - 3.7e-05 23.3 6.3 0.14 12.1 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPI35610.1 - 0.00013 21.6 1.3 0.00013 21.6 1.3 2.5 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 KPI35610.1 - 0.0011 19.3 10.6 0.012 15.9 1.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KPI35610.1 - 0.077 12.4 1.7 0.11 11.8 0.8 1.8 2 0 0 2 2 2 0 MalT-like TPR region TPR_10 PF13374.6 KPI35610.1 - 0.11 12.4 7.3 0.17 11.8 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPI35610.1 - 0.13 12.9 15.8 0.046 14.4 9.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPI35610.1 - 7.4 7.2 9.3 6.4 7.4 4.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat PH PF00169.29 KPI35611.1 - 2.5e-06 27.9 0.1 4.8e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 PH domain CorA PF01544.18 KPI35613.1 - 0.00071 19.0 5.4 0.0016 17.8 5.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SURF1 PF02104.15 KPI35613.1 - 0.026 14.8 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 SURF1 family Sigma_1s PF02454.16 KPI35613.1 - 0.051 13.6 2.0 6.1 6.9 0.4 2.4 2 0 0 2 2 2 0 Sigma 1s protein Metallophos PF00149.28 KPI35614.1 - 3e-14 54.0 0.2 5.9e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI35614.1 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Amidohydro_1 PF01979.20 KPI35615.1 - 9.6e-24 84.3 0.1 1.9e-23 83.4 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI35615.1 - 4.1e-15 56.2 4.2 2e-08 34.2 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family Abhydrolase_6 PF12697.7 KPI35616.1 - 4.1e-11 43.9 1.6 7.1e-11 43.1 1.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI35616.1 - 5.9e-09 35.5 0.0 2.6e-07 30.2 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI35616.1 - 9.3e-08 32.0 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KPI35616.1 - 0.00065 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI35616.1 - 0.00093 18.7 0.0 0.0047 16.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KPI35616.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1100 PF06500.11 KPI35616.1 - 0.045 12.5 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 KPI35616.1 - 0.15 11.5 0.0 3 7.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Sec66 PF09802.9 KPI35617.1 - 2.5e-51 173.8 3.9 6.5e-50 169.2 3.9 2.0 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 KorB PF08535.10 KPI35617.1 - 0.051 13.6 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 KorB domain SieB PF14163.6 KPI35617.1 - 0.15 11.5 0.2 4.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF4407 PF14362.6 KPI35617.1 - 0.45 9.8 3.6 0.61 9.4 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRTP PF01366.18 KPI35617.1 - 0.65 8.0 2.7 0.87 7.6 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Ndc1_Nup PF09531.10 KPI35617.1 - 0.71 8.5 5.1 0.86 8.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CENP-Q PF13094.6 KPI35618.1 - 2e-27 96.4 14.6 3e-27 95.9 14.6 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PL48 PF15903.5 KPI35618.1 - 0.19 10.7 3.4 0.69 8.8 0.1 2.1 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 NAD_binding_11 PF14833.6 KPI35619.1 - 1.6e-26 93.0 4.7 1.5e-17 63.9 0.6 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KPI35619.1 - 1.9e-26 93.1 0.1 3.9e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KPI35619.1 - 2.2e-05 24.4 0.3 3.9e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KPI35619.1 - 0.0035 17.0 0.1 0.0075 15.9 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KPI35619.1 - 0.012 15.3 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KPI35619.1 - 0.023 14.1 0.2 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPI35619.1 - 0.044 13.1 1.3 0.067 12.5 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh PF00984.19 KPI35619.1 - 0.11 12.7 0.2 0.25 11.6 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Thioredoxin PF00085.20 KPI35620.1 - 1.2e-12 47.7 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KPI35620.1 - 5.7e-07 29.2 0.0 7.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family malic PF00390.19 KPI35620.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Thioredoxin_8 PF13905.6 KPI35620.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KPI35620.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Hydant_A_N PF05378.13 KPI35621.1 - 3.8e-28 98.4 0.0 6.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPI35621.1 - 1.6e-09 37.5 0.1 5.2e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase ROK PF00480.20 KPI35621.1 - 0.039 13.4 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 ROK family BcrAD_BadFG PF01869.20 KPI35621.1 - 0.095 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Aldedh PF00171.22 KPI35622.1 - 1.4e-139 465.6 1.0 1.8e-106 356.4 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family TPR_1 PF00515.28 KPI35623.1 - 8.8e-23 79.1 0.7 9.3e-06 25.3 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35623.1 - 2.8e-22 77.0 1.2 0.00042 20.2 0.1 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI35623.1 - 3.4e-17 61.8 3.6 8.5e-06 25.4 0.1 5.0 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 KPI35623.1 - 1.4e-16 59.7 2.4 0.00033 21.2 0.2 5.8 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPI35623.1 - 3.7e-16 59.5 3.9 1.3e-06 29.0 0.8 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPI35623.1 - 1.5e-14 53.2 3.9 0.012 16.0 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KPI35623.1 - 3.2e-13 50.0 3.0 0.0059 17.1 0.1 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI35623.1 - 1e-11 44.0 0.2 0.0045 17.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KPI35623.1 - 4.8e-09 36.4 0.3 0.014 15.7 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPI35623.1 - 1.3e-08 35.0 0.7 0.0022 18.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPI35623.1 - 1.7e-08 34.5 0.9 0.0034 17.5 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI35623.1 - 3.1e-06 26.8 0.7 3.8 7.8 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPI35623.1 - 9.6e-06 25.9 0.2 2.4 9.0 0.0 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI35623.1 - 1e-05 25.7 1.2 0.032 14.5 0.2 2.8 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KPI35623.1 - 0.018 14.3 0.0 0.58 9.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1641 PF07849.11 KPI35623.1 - 0.13 12.2 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 KPI35623.1 - 0.16 11.7 1.6 3.1 7.5 0.0 3.4 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 AP_endonuc_2 PF01261.24 KPI35624.1 - 4.8e-29 101.3 0.2 6.7e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short_C2 PF13561.6 KPI35625.1 - 1.1e-52 179.0 0.6 1.2e-52 178.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35625.1 - 2.3e-39 134.9 0.7 3.1e-39 134.5 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35625.1 - 2.1e-10 40.8 0.1 3.1e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI35625.1 - 0.00011 21.8 0.1 0.00018 21.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI35625.1 - 0.0033 16.6 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPI35625.1 - 0.019 14.4 0.1 0.082 12.3 0.0 1.9 1 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase TFIIS_M PF07500.14 KPI35626.1 - 1.2e-22 80.5 2.2 2.3e-22 79.6 2.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KPI35626.1 - 4.9e-19 67.9 5.5 7.4e-19 67.3 5.5 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KPI35626.1 - 2.1e-10 40.4 0.1 5.7e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cytochrome_C7 PF14522.6 KPI35626.1 - 0.084 12.9 3.3 0.22 11.6 3.3 1.7 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_NNT PF03264.14 KPI35626.1 - 0.11 12.2 4.4 0.18 11.5 4.4 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region GST_C PF00043.25 KPI35628.1 - 4.1e-14 52.6 0.1 8.3e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI35628.1 - 1.7e-12 47.5 0.0 1.1e-11 44.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI35628.1 - 2e-09 37.7 0.0 6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI35628.1 - 1.7e-08 34.3 0.0 3.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI35628.1 - 2e-08 34.4 0.0 6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI35628.1 - 1.7e-07 31.3 0.2 5.3e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KPI35628.1 - 0.065 13.0 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3818 PF12825.7 KPI35630.1 - 3e-130 434.2 2.2 6.1e-130 433.2 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KPI35630.1 - 4.8e-39 133.3 0.3 9.5e-39 132.4 0.3 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KPI35630.1 - 9e-13 48.2 0.4 3.5e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 PX domain GFD1 PF17331.2 KPI35630.1 - 0.39 11.0 3.4 1.2 9.5 3.4 1.8 1 0 0 1 1 1 0 GFD1 mRNA transport factor adh_short_C2 PF13561.6 KPI35632.1 - 1.8e-39 135.7 0.3 2.1e-39 135.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35632.1 - 3.1e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KPI35632.1 - 1.2e-09 38.0 0.1 1.3e-08 34.6 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI35632.1 - 2e-08 34.4 2.8 7.5e-07 29.2 1.6 2.9 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KPI35632.1 - 6.1e-07 29.5 0.1 9.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPI35632.1 - 1.1e-05 24.5 0.1 1.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KPI35632.1 - 5.7e-05 22.3 0.1 8.1e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KPI35632.1 - 0.00013 21.6 0.8 0.0002 21.0 0.8 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KPI35632.1 - 0.00064 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KPI35632.1 - 0.0048 16.8 0.2 0.008 16.1 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 KPI35632.1 - 0.0083 16.2 0.3 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KPI35632.1 - 0.012 15.9 0.3 0.021 15.1 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KPI35632.1 - 0.028 13.8 0.3 0.092 12.1 0.2 1.9 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPI35632.1 - 0.028 14.7 0.2 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain DFP PF04127.15 KPI35632.1 - 0.045 13.6 1.1 0.14 12.0 0.3 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 KPI35632.1 - 0.045 12.9 0.8 0.22 10.6 0.8 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Rossmann-like PF10727.9 KPI35632.1 - 0.062 13.2 0.5 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 Rossmann-like domain F420_oxidored PF03807.17 KPI35632.1 - 0.069 13.7 0.2 0.16 12.5 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KPI35632.1 - 0.093 12.0 1.1 0.17 11.1 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LysM PF01476.20 KPI35633.1 - 0.00017 21.6 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain Fungal_trans PF04082.18 KPI35634.1 - 1.2e-35 122.8 0.5 2.1e-35 122.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_20 PF12840.7 KPI35634.1 - 0.031 14.3 0.0 0.92 9.6 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain SnoaL_2 PF12680.7 KPI35634.1 - 0.11 13.1 0.1 29 5.4 0.0 2.6 2 0 0 2 2 2 0 SnoaL-like domain APH PF01636.23 KPI35635.1 - 4.4e-09 36.6 0.1 6.3e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPI35635.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase PALP PF00291.25 KPI35636.1 - 1.1e-45 156.4 0.1 1.1e-33 116.9 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme GMC_oxred_N PF00732.19 KPI35636.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI35637.1 - 3.7e-80 270.1 0.2 4.5e-80 269.8 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KPI35637.1 - 2.6e-21 75.5 0.1 5.2e-20 71.4 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KPI35637.1 - 8e-13 48.7 0.2 2e-12 47.4 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPI35637.1 - 1.4e-08 34.6 0.4 4.9e-08 32.8 0.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI35637.1 - 7.3e-08 32.5 0.5 3.9e-07 30.2 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI35637.1 - 1.1e-07 31.4 0.1 4e-07 29.5 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI35637.1 - 4.1e-05 22.5 3.1 0.00014 20.7 0.6 2.7 2 1 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KPI35637.1 - 5.4e-05 22.6 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI35637.1 - 0.00037 19.7 0.6 0.12 11.4 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KPI35637.1 - 0.0009 18.5 0.2 0.053 12.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KPI35637.1 - 0.006 15.9 0.2 0.022 14.0 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPI35637.1 - 0.011 15.0 0.7 0.023 14.0 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KPI35637.1 - 0.065 12.5 0.3 1.5 8.0 0.0 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GDI PF00996.18 KPI35637.1 - 0.084 11.4 0.1 0.15 10.5 0.1 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.27 KPI35637.1 - 0.13 12.8 0.9 5.3 7.7 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AP_endonuc_2 PF01261.24 KPI35638.1 - 1.9e-28 99.3 0.0 2.5e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phage_P2_GpU PF06995.11 KPI35638.1 - 0.0023 17.5 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Phage P2 GpU DUF3672 PF12421.8 KPI35639.1 - 0.0097 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III protein DAO PF01266.24 KPI35642.1 - 6.2e-34 118.1 0.5 2.1e-33 116.4 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF3546 PF12066.8 KPI35642.1 - 3.2e-31 107.8 7.9 3.2e-31 107.8 7.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KPI35642.1 - 2.6e-12 46.3 0.2 5.5e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 KPI35642.1 - 1.4e-11 45.2 3.1 2.6e-11 44.2 2.0 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 Pyr_redox_3 PF13738.6 KPI35642.1 - 0.0016 17.8 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI35642.1 - 0.037 13.3 0.0 8.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI35643.1 - 1.1e-12 47.9 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI35643.1 - 1.2e-05 24.3 1.9 0.06 12.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KPI35643.1 - 1.7e-05 24.2 0.3 6e-05 22.4 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI35643.1 - 4.2e-05 23.3 5.5 0.0073 15.9 2.8 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI35643.1 - 5.2e-05 22.5 0.0 8.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI35643.1 - 0.00015 21.0 0.9 0.00061 19.0 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPI35643.1 - 0.00019 20.8 1.6 0.0037 16.6 1.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI35643.1 - 0.00046 20.4 1.2 0.0015 18.7 1.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI35643.1 - 0.002 18.6 0.3 4.7 7.8 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI35643.1 - 0.067 12.3 1.8 0.12 11.5 1.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KPI35643.1 - 0.17 11.1 0.2 0.28 10.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family SnoaL PF07366.12 KPI35644.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase SLAC1 PF03595.17 KPI35645.1 - 7.4e-71 239.0 42.2 8.4e-71 238.9 42.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PX PF00787.24 KPI35646.1 - 3.3e-18 65.7 0.4 1.2e-17 64.0 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KPI35646.1 - 9.1e-07 28.7 6.9 0.00038 20.1 0.4 2.1 1 1 1 2 2 2 2 Vps5 C terminal like Hrs_helical PF12210.8 KPI35646.1 - 0.0056 17.2 0.2 0.022 15.3 0.1 2.0 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate BAR PF03114.18 KPI35646.1 - 0.048 13.3 5.6 0.29 10.8 5.6 2.1 1 1 0 1 1 1 0 BAR domain DUF1664 PF07889.12 KPI35646.1 - 0.25 11.4 1.0 11 6.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UCH PF00443.29 KPI35647.1 - 1.8e-40 139.1 0.0 3.4e-39 134.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KPI35647.1 - 4.6e-11 42.5 1.2 1.6e-10 40.7 1.2 2.0 1 0 0 1 1 1 1 A repeated domain in UCH-protein UCH_1 PF13423.6 KPI35647.1 - 1.5e-07 31.4 0.0 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KPI35647.1 - 0.45 9.9 2.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase adh_short PF00106.25 KPI35648.1 - 2.4e-26 92.4 0.2 3e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35648.1 - 3e-19 69.5 0.2 3.6e-19 69.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35648.1 - 1.6e-07 31.4 0.2 1.9e-07 31.1 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI35648.1 - 0.00032 20.6 0.0 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Sugar_tr PF00083.24 KPI35649.1 - 5.5e-99 332.1 25.0 6.3e-99 331.9 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35649.1 - 9.8e-26 90.5 31.4 6.6e-17 61.5 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 KPI35650.1 - 2.5e-54 184.3 0.1 2e-48 165.0 0.0 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35650.1 - 6.5e-50 169.3 0.0 1.9e-40 138.4 0.0 2.1 1 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI35650.1 - 3.9e-05 23.6 0.3 0.00073 19.5 0.3 2.4 1 1 0 1 1 1 1 KR domain DFP PF04127.15 KPI35650.1 - 0.18 11.6 0.2 1.1 9.0 0.5 2.1 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Transp_cyt_pur PF02133.15 KPI35651.1 - 2.3e-57 194.8 13.9 2.6e-57 194.6 13.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.14 KPI35651.1 - 0.79 9.9 0.0 0.79 9.9 0.0 3.1 3 1 1 4 4 4 0 Heme exporter protein D (CcmD) PPR_2 PF13041.6 KPI35656.1 - 4.7e-07 29.9 0.1 0.016 15.4 0.0 4.5 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 KPI35656.1 - 0.0034 17.5 9.3 1.8 9.0 0.0 6.0 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KPI35656.1 - 0.06 13.4 0.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain MgtE_N PF03448.17 KPI35656.1 - 0.089 13.4 2.2 1.3 9.6 2.3 2.4 2 0 0 2 2 2 0 MgtE intracellular N domain Transp_cyt_pur PF02133.15 KPI35657.1 - 2.7e-34 118.7 13.2 3.3e-34 118.4 13.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ACT_3 PF10000.9 KPI35658.1 - 8.9e-19 67.2 0.1 1.9e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KPI35658.1 - 2.5e-12 46.4 0.0 5.3e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain CorA PF01544.18 KPI35658.1 - 1.3e-05 24.7 0.1 2.2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KPI35658.1 - 0.0027 16.6 0.2 0.0027 16.6 0.2 2.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) Tim17 PF02466.19 KPI35659.1 - 7.8e-07 29.5 9.0 1.1e-06 29.0 8.1 1.7 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4260 PF14079.6 KPI35661.1 - 1.8e-27 95.5 3.6 5.4e-12 45.7 0.5 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4260) adh_short_C2 PF13561.6 KPI35662.1 - 2.4e-57 194.2 0.0 2.8e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35662.1 - 6.7e-44 149.7 0.0 8.4e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35662.1 - 9.7e-09 35.4 0.0 2.4e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 KR domain WD40 PF00400.32 KPI35663.1 - 4.5e-06 27.3 0.5 6.3 7.9 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1770 PF08589.10 KPI35663.1 - 0.014 16.3 0.5 0.079 13.9 0.0 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) PQQ_3 PF13570.6 KPI35663.1 - 0.058 13.9 0.1 38 4.9 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain DUF4329 PF14220.6 KPI35663.1 - 0.097 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Glucosamine_iso PF01182.20 KPI35664.1 - 2.8e-71 240.0 0.0 3.1e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase UCH PF00443.29 KPI35665.1 - 2.9e-12 46.7 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI35665.1 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YL1 PF05764.13 KPI35665.1 - 0.0019 18.3 0.7 0.0033 17.6 0.7 1.3 1 0 0 1 1 1 1 YL1 nuclear protein PHD PF00628.29 KPI35665.1 - 0.0024 17.7 0.9 0.0024 17.7 0.9 3.4 4 0 0 4 4 4 1 PHD-finger adh_short PF00106.25 KPI35666.1 - 1.1e-28 100.1 0.2 4.2e-28 98.1 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35666.1 - 1.8e-20 73.5 0.6 5.7e-20 71.9 0.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35666.1 - 8.9e-10 38.8 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KPI35666.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THUMP PF02926.17 KPI35667.1 - 1.8e-09 37.8 2.2 3.5e-09 36.9 1.0 2.0 2 1 0 2 2 2 1 THUMP domain Aldo_ket_red PF00248.21 KPI35667.1 - 0.27 10.4 0.9 7.5 5.6 0.0 2.7 1 1 2 3 3 3 0 Aldo/keto reductase family NTR PF01759.21 KPI35667.1 - 1 9.2 3.1 2.6 7.9 0.5 2.2 2 0 0 2 2 2 0 UNC-6/NTR/C345C module PLA2_B PF01735.18 KPI35669.1 - 6.1e-72 242.6 12.7 3e-70 237.0 12.7 2.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF1479 PF07350.12 KPI35670.1 - 1.4e-113 379.8 0.0 1.6e-113 379.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KPI35670.1 - 0.041 14.1 0.1 0.42 10.8 0.2 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) TIG PF01833.24 KPI35672.1 - 3.9e-10 39.7 0.0 1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain RHD_dimer PF16179.5 KPI35672.1 - 0.041 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Rel homology dimerisation domain SR-25 PF10500.9 KPI35672.1 - 2.2 7.8 13.4 0.11 12.1 1.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EXS PF03124.14 KPI35673.1 - 4e-92 309.1 26.9 4.9e-92 308.8 26.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KPI35673.1 - 9.6e-72 243.0 10.2 9.6e-72 243.0 10.2 2.0 2 0 0 2 2 2 1 SPX domain Peptidase_C23 PF05379.11 KPI35674.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Carlavirus endopeptidase NOA36 PF06524.12 KPI35674.1 - 2.9 7.2 5.3 4 6.7 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein Arm PF00514.23 KPI35675.1 - 0.00015 21.7 15.4 0.2 11.7 0.1 7.6 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 KPI35675.1 - 0.19 11.9 1.3 5.5 7.1 0.2 3.5 4 1 1 5 5 5 0 V-ATPase subunit H RRM_1 PF00076.22 KPI35677.1 - 4.4e-05 23.2 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF202 PF02656.15 KPI35678.1 - 0.00013 22.4 3.1 0.00013 22.4 3.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF3318 PF11780.8 KPI35678.1 - 0.084 12.8 0.1 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DUF5384 PF17358.2 KPI35679.1 - 0.65 10.0 7.6 1 9.4 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5384) MFS_1 PF07690.16 KPI35680.1 - 1.9e-09 36.9 44.2 6e-09 35.3 11.2 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI35680.1 - 3.5e-05 22.4 1.1 3.5e-05 22.4 1.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TLC PF03219.14 KPI35682.1 - 0.0053 15.5 3.7 0.0062 15.3 3.7 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF5362 PF17319.2 KPI35682.1 - 1.5 8.7 8.0 7.5 6.5 0.1 3.2 4 1 0 4 4 4 0 Family of unknown function (DUF5362) DUF4079 PF13301.6 KPI35684.1 - 4.9e-06 26.8 4.5 0.019 15.1 1.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 KPI35684.1 - 0.00026 21.1 5.9 0.00072 19.7 5.9 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Adeno_E3 PF06040.11 KPI35684.1 - 0.093 12.9 0.2 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein SUR7 PF06687.12 KPI35684.1 - 1.5 8.4 6.8 0.29 10.8 3.0 1.6 2 0 0 2 2 2 0 SUR7/PalI family E1-E2_ATPase PF00122.20 KPI35685.1 - 8.1e-27 93.9 0.5 8.1e-27 93.9 0.5 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KPI35685.1 - 2.8e-20 73.5 4.6 4.8e-20 72.7 0.8 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KPI35685.1 - 2.7e-09 37.3 0.1 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain DUF3487 PF11990.8 KPI35685.1 - 0.036 13.9 2.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Peptidase_S24 PF00717.23 KPI35685.1 - 0.093 12.7 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Peptidase S24-like p450 PF00067.22 KPI35686.1 - 9e-58 196.1 0.0 5.7e-36 124.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Bd3614_N PF14442.6 KPI35686.1 - 0.034 14.4 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Isochorismatase PF00857.20 KPI35687.1 - 1.4e-28 100.3 0.0 5.3e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 KPI35687.1 - 4.8e-27 95.4 0.0 9e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FlxA PF14282.6 KPI35688.1 - 0.0045 17.0 6.8 0.0073 16.3 5.1 2.2 1 1 1 2 2 2 1 FlxA-like protein GrpE PF01025.19 KPI35688.1 - 0.036 13.7 3.4 0.061 13.0 3.0 1.5 1 1 0 1 1 1 0 GrpE RILP PF11461.8 KPI35688.1 - 0.1 12.8 0.4 0.4 11.0 0.4 2.1 1 0 0 1 1 1 0 Rab interacting lysosomal protein APG6_N PF17675.1 KPI35688.1 - 1.3 9.6 10.0 0.052 14.1 2.4 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 KPI35688.1 - 6.7 6.6 8.5 3.7 7.5 5.2 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain GFA PF04828.14 KPI35689.1 - 2.2e-14 53.6 0.5 2.9e-14 53.2 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.24 KPI35690.1 - 6.4e-70 236.2 19.0 2.2e-30 105.9 7.5 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KPI35690.1 - 1.4e-17 63.7 30.6 8.5e-14 51.2 11.7 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI35690.1 - 1.3e-05 24.7 5.7 1.3e-05 24.7 5.7 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KPI35690.1 - 0.028 12.9 5.4 0.0086 14.5 2.5 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Amastin PF07344.11 KPI35690.1 - 2.7 7.8 8.3 7.7 6.4 2.8 2.6 2 0 0 2 2 2 0 Amastin surface glycoprotein Cauli_VI PF01693.16 KPI35691.1 - 1.9e-39 133.7 5.4 4.3e-20 71.7 0.7 2.7 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KPI35691.1 - 5e-31 107.8 2.4 3e-27 95.5 0.5 2.6 1 1 1 2 2 2 2 RNase H RVT_3 PF13456.6 KPI35691.1 - 0.032 14.0 0.1 0.25 11.1 0.0 2.5 3 0 0 3 3 3 0 Reverse transcriptase-like FAD_binding_4 PF01565.23 KPI35692.1 - 6.8e-31 106.9 0.0 1.1e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KPI35692.1 - 8.7e-10 38.6 0.5 2e-09 37.5 0.4 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain zf-CCHC_5 PF14787.6 KPI35692.1 - 0.75 9.6 2.3 14 5.5 0.5 2.8 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger RNA12 PF10443.9 KPI35693.1 - 1.2e-168 561.4 0.6 3.8e-168 559.8 1.4 1.4 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 KPI35693.1 - 2.2e-06 27.4 0.0 7.2e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KPI35693.1 - 5.8e-05 23.1 0.0 0.00018 21.5 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 KPI35693.1 - 0.00079 19.5 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_1 PF00076.22 KPI35694.1 - 3.6e-20 71.5 0.0 1.5e-14 53.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPI35694.1 - 0.016 14.8 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KPI35694.1 - 0.06 13.4 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 DUF3040 PF11239.8 KPI35695.1 - 0.89 9.9 9.9 3.5 8.0 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) 6PF2K PF01591.18 KPI35696.1 - 5.1e-64 215.6 0.0 4.8e-44 150.3 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KPI35696.1 - 4.1e-29 101.7 0.0 8.7e-23 81.0 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KPI35696.1 - 0.00083 19.5 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain TMEM252 PF15664.5 KPI35696.1 - 0.063 13.0 0.3 0.41 10.4 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 252 family KTI12 PF08433.10 KPI35696.1 - 0.14 11.6 0.0 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mito_carr PF00153.27 KPI35697.1 - 2.6e-29 101.0 4.2 1.2e-15 57.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PRELI PF04707.14 KPI35698.1 - 4.6e-24 85.0 0.0 1.8e-21 76.6 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family SWIM PF04434.17 KPI35700.1 - 0.0041 16.7 4.9 0.42 10.3 0.1 2.3 2 0 0 2 2 2 2 SWIM zinc finger GCP_C_terminal PF04130.13 KPI35701.1 - 3.8e-25 89.0 0.0 6e-23 81.8 0.0 2.5 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KPI35701.1 - 8.7e-22 78.1 0.0 1.3e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 KPI35701.1 - 0.006 15.0 4.3 0.049 12.0 3.0 2.5 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Nucleo_P87 PF07267.11 KPI35701.1 - 0.084 11.7 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LPD28 PF18843.1 KPI35702.1 - 0.1 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 28 HIP1_clath_bdg PF16515.5 KPI35703.1 - 0.00053 20.5 5.1 0.0021 18.7 5.1 2.0 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF641 PF04859.12 KPI35703.1 - 0.0011 19.2 3.1 0.0011 19.2 3.1 1.8 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) SlyX PF04102.12 KPI35703.1 - 0.0042 17.7 3.3 0.014 16.0 3.3 2.0 1 0 0 1 1 1 1 SlyX SAE2 PF08573.10 KPI35703.1 - 0.014 16.5 0.4 0.27 12.4 0.0 2.7 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus USP8_interact PF08941.10 KPI35703.1 - 0.045 13.6 0.9 0.093 12.5 0.9 1.4 1 0 0 1 1 1 0 USP8 interacting DUF1043 PF06295.12 KPI35703.1 - 0.07 13.1 2.0 0.16 12.0 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Borrelia_P83 PF05262.11 KPI35703.1 - 0.079 11.4 1.7 0.13 10.8 1.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SKA2 PF16740.5 KPI35703.1 - 0.15 11.8 3.5 0.32 10.8 3.1 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Mod_r PF07200.13 KPI35703.1 - 0.6 10.2 6.8 0.85 9.7 5.7 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DHR10 PF18595.1 KPI35703.1 - 0.87 9.7 11.0 1.8 8.6 10.3 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DivIC PF04977.15 KPI35703.1 - 1.3 8.8 4.7 3.6 7.4 4.7 1.7 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 KPI35703.1 - 2.6 6.8 8.2 1.9 7.3 5.1 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Fungal_trans PF04082.18 KPI35705.1 - 1.8e-12 46.9 0.2 3.4e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MctB PF11382.8 KPI35706.1 - 0.0045 16.7 0.9 1.2 8.7 0.0 2.0 1 1 1 2 2 2 2 Copper transport outer membrane protein, MctB Inhibitor_I9 PF05922.16 KPI35706.1 - 0.021 15.5 0.0 0.031 14.9 0.0 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 VHS PF00790.19 KPI35707.1 - 7.1e-42 142.6 0.0 2e-41 141.2 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KPI35707.1 - 1.6e-20 73.2 0.0 5.2e-20 71.5 0.0 2.0 1 0 0 1 1 1 1 GAT domain Methyltransf_23 PF13489.6 KPI35707.1 - 7e-14 52.0 0.0 1.8e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI35707.1 - 1.2e-09 38.7 0.0 3.8e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI35707.1 - 2.9e-09 36.9 0.0 5.4e-07 29.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Alpha_adaptinC2 PF02883.20 KPI35707.1 - 1.3e-07 31.9 1.4 1.3e-07 31.9 1.4 2.1 2 1 0 2 2 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KPI35707.1 - 1.6e-06 27.6 0.1 5.5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 GGA N-GAT domain Methyltransf_11 PF08241.12 KPI35707.1 - 3e-05 24.6 0.0 7.9e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI35707.1 - 7e-05 23.5 0.0 0.00027 21.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KPI35707.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KPI35707.1 - 0.035 13.6 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KPI35707.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KPI35707.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Mei5 PF10376.9 KPI35707.1 - 0.21 11.4 2.0 0.4 10.5 2.0 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Ras PF00071.22 KPI35708.1 - 2.3e-63 212.6 0.2 2.7e-63 212.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI35708.1 - 4.5e-35 120.5 0.2 6.3e-35 120.0 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI35708.1 - 3.3e-13 49.4 0.0 4.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPI35708.1 - 1.6e-07 31.4 0.1 2.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI35708.1 - 8.1e-05 22.6 0.2 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KPI35708.1 - 0.00026 20.6 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI35708.1 - 0.00083 18.8 0.1 0.0013 18.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KPI35708.1 - 0.0032 17.7 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KPI35708.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KPI35708.1 - 0.018 15.1 0.1 0.066 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPI35708.1 - 0.025 14.9 0.1 0.041 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KPI35708.1 - 0.031 14.8 0.1 0.043 14.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KPI35708.1 - 0.036 13.8 0.1 0.087 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KPI35708.1 - 0.05 13.0 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KPI35708.1 - 0.11 12.3 0.7 0.12 12.2 0.7 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KPI35708.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KPI35708.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF3455 PF11937.8 KPI35709.1 - 4.5e-14 53.1 0.1 1.1e-06 29.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3455) Catalase PF00199.19 KPI35711.1 - 1.2e-176 587.5 0.1 1.7e-176 587.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KPI35711.1 - 8.7e-13 48.3 0.0 2.5e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive PP-binding PF00550.25 KPI35711.1 - 0.065 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site KNOX2 PF03791.13 KPI35712.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain adh_short PF00106.25 KPI35713.1 - 3.2e-35 121.4 0.0 4.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35713.1 - 9.6e-23 81.0 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35713.1 - 0.00027 20.9 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 KR domain CFIA_Pcf11 PF11526.8 KPI35714.1 - 2.2e-06 28.0 0.1 4e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KPI35714.1 - 1.6e-05 25.6 0.0 3.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_11 PF16622.5 KPI35714.1 - 0.067 13.0 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type VHS PF00790.19 KPI35714.1 - 0.084 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 VHS domain zf-ISL3 PF14690.6 KPI35714.1 - 0.096 13.4 0.3 0.2 12.4 0.3 1.5 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Hexapep_loop PF18776.1 KPI35714.1 - 0.25 11.0 0.6 18 5.0 0.1 2.5 2 0 0 2 2 2 0 Hexapeptide repeat including loop CENP-C_C PF11699.8 KPI35717.1 - 2.9e-28 97.9 0.1 4.8e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KPI35717.1 - 2.3e-10 41.3 4.5 2.3e-10 41.3 4.5 4.0 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KPI35717.1 - 2.8e-06 26.9 0.0 6.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPI35717.1 - 0.04 13.5 0.1 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Cupin THEG4 PF15834.5 KPI35717.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.6 1 1 0 1 1 1 0 Testis highly expressed protein 4 Cupin_3 PF05899.12 KPI35717.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Rad51 PF08423.11 KPI35718.1 - 4.6e-38 130.9 0.0 6.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KPI35718.1 - 4.2e-07 29.7 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KPI35718.1 - 1.6e-05 24.6 0.1 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KPI35718.1 - 0.018 14.4 0.0 0.052 12.9 0.1 1.7 2 0 0 2 2 2 0 KaiC Abhydrolase_2 PF02230.16 KPI35719.1 - 8.2e-15 55.2 0.0 9.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KPI35719.1 - 0.054 12.7 0.1 12 5.0 0.2 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPI35719.1 - 0.17 11.7 0.6 0.44 10.4 0.6 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.28 KPI35720.1 - 1.9e-70 237.6 0.0 2.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI35720.1 - 1.8e-10 41.7 0.1 3.6e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KPI35721.1 - 3.9e-43 147.3 0.0 4.5e-25 88.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPI35721.1 - 2.4e-40 139.0 18.6 3.3e-19 69.6 7.1 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KPI35721.1 - 6e-13 48.7 0.4 0.0054 16.2 0.0 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPI35721.1 - 1.3e-08 35.0 0.1 0.62 9.8 0.0 4.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPI35721.1 - 2e-06 28.1 0.4 0.13 12.6 0.7 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPI35721.1 - 2.5e-06 27.5 0.1 0.017 15.0 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 KPI35721.1 - 5.7e-06 27.0 0.6 0.13 12.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KPI35721.1 - 0.00014 21.6 1.1 0.041 13.6 0.4 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KPI35721.1 - 0.00082 19.4 0.1 0.44 10.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KPI35721.1 - 0.0016 18.0 0.1 0.66 9.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KPI35721.1 - 0.0019 17.6 0.5 0.092 12.1 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.17 KPI35721.1 - 0.006 16.7 0.5 0.006 16.7 0.5 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KPI35721.1 - 0.0093 16.4 0.1 3.5 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KPI35721.1 - 0.0095 16.1 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KPI35721.1 - 0.012 15.2 0.3 0.76 9.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KPI35721.1 - 0.018 15.0 0.7 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KPI35721.1 - 0.019 14.2 0.5 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KPI35721.1 - 0.027 13.5 0.1 1.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KPI35721.1 - 0.028 14.1 2.8 13 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 KPI35721.1 - 0.052 12.5 1.5 1.2 7.9 0.3 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 KPI35721.1 - 0.058 13.4 0.7 1.1 9.2 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KPI35721.1 - 0.061 12.9 2.5 1.8 8.1 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KPI35721.1 - 0.15 11.7 2.6 6.6 6.4 0.0 3.1 4 0 0 4 4 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 KPI35721.1 - 0.19 11.5 0.5 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KPI35721.1 - 0.47 9.6 3.8 20 4.3 0.2 3.5 4 0 0 4 4 4 0 NB-ARC domain MPC PF03650.13 KPI35722.1 - 0.043 14.0 0.7 0.58 10.3 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers Aminotran_4 PF01063.19 KPI35723.1 - 4.3e-21 75.8 0.0 5.6e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ECH_1 PF00378.20 KPI35724.1 - 2.2e-26 92.7 0.0 2.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI35724.1 - 5.1e-18 65.7 0.0 6.2e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ATP-synt_ab PF00006.25 KPI35724.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3128 PF11326.8 KPI35726.1 - 1.7e-24 86.0 2.6 4.1e-24 84.7 2.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Nsp1_C PF05064.13 KPI35726.1 - 0.012 15.4 1.7 0.016 15.0 0.4 1.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region TBCA PF02970.16 KPI35727.1 - 0.085 13.2 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A Coagulase PF08764.10 KPI35727.1 - 0.16 12.1 0.2 0.23 11.6 0.2 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Med1 PF10744.9 KPI35728.1 - 1.6e-12 47.2 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 PhoLip_ATPase_C PF16212.5 KPI35729.1 - 0.0022 17.8 1.5 0.0022 17.8 1.5 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal DUF1211 PF06736.11 KPI35729.1 - 0.54 10.7 3.6 21 5.7 3.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) DUF4199 PF13858.6 KPI35729.1 - 6.1 7.2 5.7 5.5 7.4 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) MitMem_reg PF13012.6 KPI35730.1 - 1.6e-37 128.3 0.0 2.5e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KPI35730.1 - 6.3e-27 93.9 0.0 2.2e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KPI35730.1 - 0.46 10.2 4.9 0.68 9.6 4.9 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain FAM176 PF14851.6 KPI35730.1 - 0.65 9.6 4.0 7.2 6.3 1.8 2.4 2 0 0 2 2 2 0 FAM176 family Na_H_Exchanger PF00999.21 KPI35731.1 - 3.6e-50 170.9 14.8 4.7e-50 170.5 14.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YtpI PF14007.6 KPI35731.1 - 2.5 8.3 7.3 13 6.0 0.0 3.4 4 0 0 4 4 4 0 YtpI-like protein DUF3810 PF12725.7 KPI35731.1 - 3.1 7.1 6.3 0.46 9.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Aldo_ket_red PF00248.21 KPI35732.1 - 3.6e-67 226.6 0.0 5.3e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.8 KPI35732.1 - 4.1e-22 78.5 0.0 6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.18 KPI35733.1 - 8.2e-107 357.2 0.0 9.9e-107 357.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPI35733.1 - 5.9e-18 64.8 0.0 1.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KPI35733.1 - 4.1e-08 32.6 0.1 3.3e-06 26.3 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KPI35733.1 - 6.1e-08 32.2 0.2 9.2e-08 31.6 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KPI35733.1 - 0.0037 16.5 0.3 0.0078 15.5 0.2 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KPI35733.1 - 0.0063 15.9 0.7 0.0099 15.3 0.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KPI35733.1 - 0.013 14.9 0.3 0.038 13.4 0.2 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KPI35733.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KPI35733.1 - 0.06 12.7 0.1 0.18 11.1 0.1 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Clr5 PF14420.6 KPI35734.1 - 1.8e-15 56.9 3.2 4.3e-15 55.7 3.2 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KPI35734.1 - 7.2e-06 26.2 0.9 0.34 11.2 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI35734.1 - 0.00011 22.8 1.6 0.29 11.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPI35734.1 - 0.00078 19.2 1.6 1.1 9.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35734.1 - 0.0023 17.9 0.2 2.1 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat p450 PF00067.22 KPI35735.1 - 1.3e-68 231.9 0.0 1.6e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WLM PF08325.10 KPI35736.1 - 2.5e-47 161.4 0.1 4.5e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 WLM domain eIF3_p135 PF12807.7 KPI35736.1 - 0.048 13.7 0.6 0.086 12.9 0.1 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 SprT-like PF10263.9 KPI35736.1 - 0.085 12.7 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 SprT-like family SH2_2 PF14633.6 KPI35737.1 - 1.4e-78 263.3 0.0 1.7e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 SH2 domain SH2 PF00017.24 KPI35737.1 - 0.00037 20.5 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 SH2 domain YwhD PF08741.10 KPI35737.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 YwhD family tRNA-synt_1b PF00579.25 KPI35738.1 - 5.1e-12 45.7 0.0 1.3e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) ATF7IP_BD PF16788.5 KPI35738.1 - 0.039 14.1 5.5 0.073 13.2 5.5 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain Suf PF05843.14 KPI35738.1 - 0.24 11.3 5.0 0.36 10.8 5.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NST1 PF13945.6 KPI35738.1 - 0.25 11.5 7.9 0.45 10.6 7.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_S30 PF01577.16 KPI35738.1 - 0.59 9.7 4.4 1.1 8.8 4.4 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease DUF3759 PF12585.8 KPI35739.1 - 4.4e-38 129.2 5.2 7.4e-38 128.5 5.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) HET PF06985.11 KPI35740.1 - 7e-31 107.5 1.3 1.1e-30 107.0 1.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KPI35741.1 - 4.7e-07 29.1 0.1 7.8e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.8 KPI35742.1 - 6.3e-18 64.9 0.6 1.3e-17 63.9 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI35742.1 - 0.14 12.3 3.4 0.3 11.2 3.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor CorA PF01544.18 KPI35743.1 - 1.6e-15 57.2 0.8 8.4e-15 54.9 0.6 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Srab PF10292.9 KPI35743.1 - 0.002 17.1 0.2 0.0033 16.4 0.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Phage_holin_3_6 PF07332.11 KPI35743.1 - 0.0054 16.8 0.5 0.011 15.7 0.5 1.5 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3021 PF11457.8 KPI35743.1 - 0.013 15.8 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF2207 PF09972.9 KPI35743.1 - 0.026 13.3 0.3 0.036 12.8 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YrvL PF14184.6 KPI35743.1 - 0.039 14.1 2.1 0.079 13.1 2.1 1.4 1 0 0 1 1 1 0 Regulatory protein YrvL DUF2721 PF11026.8 KPI35743.1 - 0.051 13.5 2.8 0.093 12.6 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Prefoldin_2 PF01920.20 KPI35743.1 - 0.12 12.3 2.5 0.21 11.6 2.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit NTP_transf_9 PF04248.12 KPI35744.1 - 6.2e-33 112.5 0.1 6e-26 90.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) RSN1_7TM PF02714.15 KPI35745.1 - 9.4e-55 185.8 25.1 1.2e-45 155.9 15.2 3.3 2 1 1 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPI35745.1 - 8.1e-39 132.9 0.4 8.1e-39 132.9 0.4 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPI35745.1 - 5.9e-24 85.2 0.0 8.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPI35745.1 - 3.1e-14 52.9 0.0 1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter FAD_binding_3 PF01494.19 KPI35746.1 - 3.8e-46 157.9 0.0 5.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPI35746.1 - 1.5e-05 24.3 0.2 0.00029 20.1 0.2 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI35746.1 - 2.7e-05 23.5 0.0 5.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI35746.1 - 3e-05 24.2 0.1 7.4e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPI35746.1 - 3.7e-05 22.6 0.0 6.9e-05 21.7 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KPI35746.1 - 0.00016 20.8 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KPI35746.1 - 0.0004 20.1 0.1 0.017 14.7 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI35746.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPI35746.1 - 0.003 16.9 0.0 0.0071 15.6 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI35746.1 - 0.0034 16.8 0.0 0.0082 15.5 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KPI35746.1 - 0.0039 16.3 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPI35746.1 - 0.049 12.5 0.1 0.094 11.5 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KPI35746.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI35746.1 - 0.068 13.2 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 KPI35746.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cyclin PF08613.11 KPI35747.1 - 1.9e-29 103.1 10.5 3e-28 99.2 10.5 2.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KPI35747.1 - 0.00096 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIA PF03153.13 KPI35747.1 - 0.013 15.5 9.1 0.019 15.0 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KPI35747.1 - 6.1 5.3 9.8 7.7 4.9 9.8 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 KPI35747.1 - 6.5 6.6 17.2 11 5.8 17.2 1.4 1 0 0 1 1 1 0 SPX domain HTH_44 PF14641.6 KPI35748.1 - 4.6e-33 114.1 0.2 4.6e-33 114.1 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KPI35748.1 - 5.3e-26 91.0 0.0 9.7e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KPI35748.1 - 3.4e-21 75.6 0.0 1.9e-20 73.1 0.0 2.3 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KPI35748.1 - 1.6e-15 57.5 30.1 1.6e-15 57.5 30.1 4.3 4 0 0 4 4 4 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KPI35748.1 - 2.4e-06 28.3 1.2 1.9e-05 25.5 0.5 3.0 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 KPI35748.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Tex_N PF09371.10 KPI35748.1 - 0.1 12.3 6.6 3.7 7.2 0.0 4.3 5 1 0 5 5 5 0 Tex-like protein N-terminal domain FHA PF00498.26 KPI35749.1 - 2.9e-14 53.1 0.0 5.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPI35749.1 - 0.0007 19.9 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Astro_capsid_p PF12226.8 KPI35749.1 - 2 7.5 17.6 1.4 8.0 1.7 2.6 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Sugar_tr PF00083.24 KPI35750.1 - 1.2e-88 297.9 18.7 1.5e-88 297.7 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35750.1 - 1.2e-12 47.4 45.2 1.9e-08 33.6 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPI35750.1 - 5.3 6.8 7.8 20 4.9 2.7 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AIRC PF00731.20 KPI35751.1 - 0.0016 18.1 0.7 0.021 14.4 0.1 2.6 2 0 0 2 2 2 1 AIR carboxylase RVT_3 PF13456.6 KPI35751.1 - 0.022 14.6 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like CAP_GLY PF01302.25 KPI35752.1 - 8.1e-16 57.8 5.9 1.7e-15 56.8 5.9 1.5 1 1 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KPI35752.1 - 1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KPI35752.1 - 0.0036 17.0 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ldi PF18566.1 KPI35753.1 - 1.8e-81 274.1 0.0 2.3e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase DUF1772 PF08592.11 KPI35753.1 - 0.075 13.4 8.9 0.086 13.1 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Hfx_Cass5 PF18287.1 KPI35753.1 - 0.27 11.5 0.7 0.74 10.1 0.1 2.0 2 0 0 2 2 2 0 Integron Cassette Protein Hfx_Cass5 UPF0242 PF06785.11 KPI35754.1 - 0.21 11.7 7.3 1.3 9.1 3.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 KPI35754.1 - 0.89 9.7 6.2 0.58 10.3 0.7 2.8 2 1 1 3 3 3 0 TolA binding protein trimerisation Glyco_hydro_17 PF00332.18 KPI35755.1 - 6.7e-05 22.6 1.2 0.00046 19.9 0.3 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 JmjC PF02373.22 KPI35755.1 - 0.043 14.2 0.1 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase KDZ PF18758.1 KPI35755.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Pkinase PF00069.25 KPI35756.1 - 2e-73 247.0 0.0 2.9e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI35756.1 - 3.9e-38 131.2 0.0 6.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KPI35756.1 - 2.8e-17 63.3 0.0 2.5e-06 27.9 0.0 3.4 3 0 0 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KPI35756.1 - 7.2e-16 58.0 0.1 2e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KPI35756.1 - 7.4e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KPI35756.1 - 0.005 16.5 0.2 0.0098 15.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KPI35756.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPI35756.1 - 0.019 13.9 0.2 0.031 13.2 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 KPI35756.1 - 0.091 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RNase_HII PF01351.18 KPI35757.1 - 9.3e-51 172.5 0.0 1.2e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII CoA_transf_3 PF02515.17 KPI35760.1 - 4e-66 223.6 0.0 9.8e-66 222.3 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Tudor_2 PF18104.1 KPI35760.1 - 0.093 12.4 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain HOOK PF05622.12 KPI35761.1 - 1.1e-21 76.7 58.1 1.8e-16 59.5 56.1 4.0 1 1 1 2 2 2 2 HOOK protein KELK PF15796.5 KPI35761.1 - 0.0019 18.6 3.0 0.0019 18.6 3.0 5.3 3 1 1 4 4 4 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase KASH_CCD PF14662.6 KPI35761.1 - 0.0031 17.4 16.9 0.0031 17.4 16.9 4.1 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 or KASH TelA PF05816.11 KPI35761.1 - 0.021 13.9 0.6 0.021 13.9 0.6 4.9 3 1 2 5 5 5 0 Toxic anion resistance protein (TelA) TMEM192 PF14802.6 KPI35761.1 - 0.19 10.8 0.7 0.5 9.4 0.7 1.7 1 0 0 1 1 1 0 TMEM192 family PKcGMP_CC PF16808.5 KPI35761.1 - 0.2 11.5 0.2 0.2 11.5 0.2 5.6 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KPI35761.1 - 0.25 10.6 48.3 0.25 10.7 19.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Flu_M1_C PF08289.11 KPI35761.1 - 0.67 10.2 5.1 0.18 12.1 0.4 2.5 2 1 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain FlaC_arch PF05377.11 KPI35761.1 - 8.2 6.9 27.7 0.58 10.6 1.0 5.8 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 KPI35762.1 - 5.9e-63 212.7 0.0 7.4e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI35762.1 - 8.6e-33 113.7 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI35762.1 - 3.6e-05 22.7 0.2 7.2e-05 21.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KPI35762.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KPI35762.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KPI35762.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TPR_1 PF00515.28 KPI35763.1 - 9e-40 132.9 19.8 5.4e-06 26.0 0.0 10.8 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35763.1 - 1.3e-35 118.6 16.6 0.00011 22.0 0.0 10.9 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KPI35763.1 - 1.4e-23 81.1 17.6 0.002 18.2 0.2 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI35763.1 - 2.8e-23 81.3 19.2 2.6e-06 27.0 0.0 7.7 6 1 2 8 8 7 5 TPR repeat TPR_16 PF13432.6 KPI35763.1 - 6.7e-20 71.5 3.7 9.1e-05 23.0 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KPI35763.1 - 9.3e-19 66.4 3.1 0.0008 19.6 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPI35763.1 - 5.4e-16 58.7 21.3 0.00017 21.8 0.4 7.9 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KPI35763.1 - 1.8e-13 50.8 21.7 0.00052 20.5 0.9 6.9 4 2 3 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KPI35763.1 - 1.1e-12 47.0 16.5 0.14 12.2 0.1 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KPI35763.1 - 1.3e-10 41.2 10.4 9.8e-05 22.4 0.4 6.0 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPI35763.1 - 1e-08 35.3 24.3 0.37 11.7 0.3 9.1 4 3 7 11 11 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI35763.1 - 1.5e-08 34.7 12.2 0.3 11.3 0.0 5.5 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KPI35763.1 - 4.5e-08 32.6 6.8 0.079 12.2 0.8 4.9 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KPI35763.1 - 5.4e-05 22.9 21.1 0.25 11.3 0.2 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KPI35763.1 - 0.00019 20.9 6.1 0.0082 15.6 4.0 3.3 1 1 1 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 KPI35763.1 - 0.00065 20.2 23.5 3.8 8.4 0.0 8.2 9 0 0 9 9 7 2 Tetratricopeptide repeat Sel1 PF08238.12 KPI35763.1 - 0.0013 19.3 0.7 9.8 7.0 0.0 4.5 4 0 0 4 4 3 0 Sel1 repeat NARP1 PF12569.8 KPI35763.1 - 0.0019 17.2 0.2 0.0019 17.2 0.2 3.9 2 2 2 4 4 3 2 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 KPI35763.1 - 0.0019 18.2 8.3 11 6.1 0.0 5.3 3 1 2 5 5 5 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 KPI35763.1 - 0.033 13.6 24.0 1.3 8.6 0.1 7.2 8 0 0 8 8 7 0 SHNi-TPR PknG_TPR PF16918.5 KPI35763.1 - 0.062 12.0 0.4 0.26 10.0 0.1 2.1 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat MIT PF04212.18 KPI35763.1 - 0.16 12.0 14.7 5.9 7.0 0.1 6.1 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 KPI35763.1 - 0.33 11.1 9.3 5.4 7.2 0.2 4.6 4 1 1 5 5 4 0 Anaphase-promoting complex subunit 5 MAS20 PF02064.15 KPI35763.1 - 1.4 9.0 17.9 0.39 10.8 2.0 5.0 6 2 1 7 7 6 0 MAS20 protein import receptor TPR_20 PF14561.6 KPI35763.1 - 4.1 7.8 9.7 14 6.1 0.6 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 KPI35764.1 - 1.2e-66 225.1 0.0 1.7e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI35764.1 - 2.1e-12 47.8 0.0 5.1e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pilosulin PF17499.2 KPI35764.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Ant venom peptides F-box_4 PF15966.5 KPI35765.1 - 0.044 13.7 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 F-box SBF_like PF13593.6 KPI35766.1 - 5.9e-74 249.2 25.1 6.7e-74 249.0 25.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KPI35766.1 - 8.7e-12 45.1 8.4 8.7e-12 45.1 8.4 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family Med1 PF10744.9 KPI35767.1 - 9e-31 107.3 0.2 1.2e-30 106.9 0.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF4071 PF13281.6 KPI35768.1 - 0.053 12.6 0.6 0.085 11.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Aldolase_II PF00596.21 KPI35769.1 - 4.6e-47 160.4 0.1 6.1e-47 160.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Xan_ur_permease PF00860.20 KPI35770.1 - 0.34 9.5 7.3 0.013 14.2 1.4 1.6 2 0 0 2 2 2 0 Permease family MotA_ExbB PF01618.16 KPI35770.1 - 0.55 10.0 1.7 0.81 9.4 0.2 1.9 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Abhydrolase_9_N PF15420.6 KPI35770.1 - 2.7 7.9 6.9 0.31 11.0 0.4 2.2 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DAO PF01266.24 KPI35771.1 - 8.7e-37 127.5 1.6 1.1e-36 127.1 1.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KPI35771.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_9 PF13454.6 KPI35771.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KPI35771.1 - 0.19 12.0 0.1 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KPI35773.1 - 5.1e-15 55.4 0.0 1.6e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35773.1 - 8.1e-06 25.6 0.0 3.8e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35773.1 - 0.037 13.9 0.2 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 KR domain Gar1 PF04410.14 KPI35774.1 - 1.7e-41 141.6 0.0 3.3e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Spore_YpjB PF09577.10 KPI35775.1 - 0.062 13.1 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) HbrB PF08539.11 KPI35775.1 - 0.86 9.6 4.0 5.7 6.9 0.1 2.7 2 1 0 2 2 2 0 HbrB-like Acyl-CoA_dh_1 PF00441.24 KPI35776.1 - 1.3e-32 113.1 1.1 2e-32 112.5 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI35776.1 - 2.6e-21 75.6 0.0 4.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI35776.1 - 1.7e-18 67.3 0.0 4.3e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPI35776.1 - 3.9e-17 62.8 1.4 5.8e-17 62.2 0.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5339 PF17274.2 KPI35777.1 - 0.026 15.4 0.1 0.047 14.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5339) Gp-FAR-1 PF05823.12 KPI35777.1 - 0.045 14.1 0.3 0.11 12.8 0.3 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ZnuA PF01297.17 KPI35777.1 - 0.055 12.9 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic AKNA PF12443.8 KPI35777.1 - 0.089 13.5 0.2 0.33 11.6 0.2 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor BSD PF03909.17 KPI35777.1 - 0.1 12.6 0.0 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 BSD domain PPR PF01535.20 KPI35777.1 - 0.15 12.4 0.1 0.65 10.4 0.0 2.1 2 0 0 2 2 2 0 PPR repeat ECH_1 PF00378.20 KPI35778.1 - 2.9e-39 134.9 0.0 7.2e-39 133.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI35778.1 - 5e-29 101.9 0.0 4e-28 98.9 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ADH_zinc_N PF00107.26 KPI35779.1 - 2.2e-26 92.4 0.2 3.4e-26 91.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI35779.1 - 1.1e-23 83.2 2.7 1.1e-23 83.2 2.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI35779.1 - 2.8e-06 28.4 0.1 5.2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KPI35779.1 - 0.09 12.2 0.4 0.21 11.0 0.3 1.7 1 1 1 2 2 2 0 short chain dehydrogenase EMP24_GP25L PF01105.24 KPI35780.1 - 0.00033 20.7 0.3 0.00051 20.0 0.3 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribonucleas_3_3 PF14622.6 KPI35780.1 - 0.0011 19.2 0.4 0.48 10.6 0.0 3.1 2 1 1 3 3 3 2 Ribonuclease-III-like BLOC1S3 PF15753.5 KPI35780.1 - 0.018 15.2 1.7 0.4 10.8 2.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4407 PF14362.6 KPI35780.1 - 0.94 8.8 5.3 11 5.2 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S49_N PF08496.10 KPI35780.1 - 2.4 8.2 5.1 3.9 7.5 5.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ADH_zinc_N_2 PF13602.6 KPI35781.1 - 3.1e-17 63.9 0.0 6.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPI35781.1 - 2.2e-10 40.6 0.0 7.3e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI35781.1 - 0.0097 15.8 0.0 0.025 14.4 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FMO-like PF00743.19 KPI35782.1 - 3.2e-17 62.2 0.7 1.6e-16 59.9 0.4 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI35782.1 - 2.6e-08 34.0 0.0 7.9e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI35782.1 - 0.00049 19.3 0.0 0.038 13.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI35782.1 - 0.001 18.4 0.2 0.013 14.8 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI35782.1 - 0.0011 18.3 0.2 2.7 7.1 0.2 3.8 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI35782.1 - 0.009 16.0 0.0 0.3 11.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KPI35782.1 - 0.056 12.7 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KPI35782.1 - 0.94 10.1 0.0 0.94 10.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyrid_ox_like PF16242.5 KPI35783.1 - 2.3e-17 63.0 0.1 4.2e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KPI35783.1 - 8.3e-07 29.1 0.0 2.2e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KPI35783.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative FMN-binding domain FAD_binding_3 PF01494.19 KPI35784.1 - 7.1e-18 65.0 0.1 2.1e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI35784.1 - 7.1e-10 38.6 0.0 2.8e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI35784.1 - 1.7e-07 31.2 0.6 0.00018 21.2 1.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPI35784.1 - 8.9e-07 28.5 0.1 0.002 17.5 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI35784.1 - 1.7e-06 28.1 0.2 3.5e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPI35784.1 - 5.2e-05 22.5 0.5 0.0032 16.6 0.6 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPI35784.1 - 0.00021 20.1 0.1 0.015 14.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Rossmann-like PF10727.9 KPI35784.1 - 0.00024 20.9 0.3 0.00042 20.2 0.3 1.4 1 0 0 1 1 1 1 Rossmann-like domain Lycopene_cycl PF05834.12 KPI35784.1 - 0.0008 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI35784.1 - 0.00084 18.5 0.9 0.0013 17.9 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPI35784.1 - 0.0034 16.7 0.4 0.0059 15.9 0.2 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KPI35784.1 - 0.0043 16.0 0.5 0.19 10.5 0.3 2.7 3 0 0 3 3 3 1 Tryptophan halogenase 3HCDH_N PF02737.18 KPI35784.1 - 0.0083 16.0 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPI35784.1 - 0.0097 16.1 0.1 0.056 13.6 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KPI35784.1 - 0.021 15.4 0.2 0.09 13.3 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPI35784.1 - 0.023 13.7 0.0 0.082 12.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KPI35784.1 - 0.028 13.7 0.1 0.2 10.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPI35784.1 - 0.058 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KPI35784.1 - 0.066 13.2 0.1 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KPI35784.1 - 0.17 11.2 0.3 0.24 10.7 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPI35784.1 - 0.18 11.1 0.3 0.44 9.8 0.2 1.6 2 0 0 2 2 2 0 Thi4 family Pro_CA PF00484.19 KPI35785.1 - 2.1e-05 24.9 0.1 9.4e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Carbonic anhydrase AIM24 PF01987.17 KPI35786.1 - 4.3e-49 167.1 0.0 9.9e-49 165.9 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 Aph-1 PF06105.12 KPI35786.1 - 0.046 13.1 0.4 0.075 12.4 0.4 1.2 1 0 0 1 1 1 0 Aph-1 protein Dyp_perox PF04261.12 KPI35787.1 - 5.1e-09 35.6 0.0 6e-08 32.1 0.0 2.4 3 0 0 3 3 3 1 Dyp-type peroxidase family Zn_clus PF00172.18 KPI35788.1 - 0.00025 21.1 2.4 0.00025 21.1 2.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI35788.1 - 0.0017 17.3 0.4 0.0017 17.3 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3301 PF11743.8 KPI35788.1 - 0.12 12.1 2.3 0.5 10.1 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) V_ATPase_I PF01496.19 KPI35788.1 - 7.8 4.3 7.4 12 3.6 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MARVEL PF01284.23 KPI35789.1 - 1e-22 80.7 16.4 1.2e-22 80.5 16.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain TssN PF17555.2 KPI35789.1 - 0.3 10.4 1.5 0.39 10.0 1.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Glyoxalase PF00903.25 KPI35790.1 - 3.7e-10 40.1 5.1 3e-08 33.9 1.3 2.8 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPI35790.1 - 0.004 17.4 0.4 0.26 11.6 0.2 2.9 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cyclase PF04199.13 KPI35791.1 - 3e-10 40.5 0.0 4.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Histone PF00125.24 KPI35792.1 - 1.5e-46 158.0 1.0 1.9e-46 157.7 1.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KPI35792.1 - 9.3e-06 25.9 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KPI35792.1 - 7.9e-05 22.7 0.1 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KPI35792.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KPI35792.1 - 0.047 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CPL PF08144.11 KPI35793.1 - 7.1e-27 94.5 0.3 1.9e-25 89.9 0.0 3.0 2 1 1 3 3 3 1 CPL (NUC119) domain Ribosomal_L32p PF01783.23 KPI35794.1 - 8.9e-17 61.1 5.6 1.3e-16 60.6 5.6 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KPI35794.1 - 0.003 16.9 4.0 0.005 16.2 4.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KPI35794.1 - 0.039 13.9 0.5 0.057 13.4 0.5 1.2 1 0 0 1 1 1 0 zinc-ribbons PolC_DP2 PF03833.13 KPI35794.1 - 0.048 11.5 0.7 0.051 11.4 0.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1477 PF07346.11 KPI35794.1 - 0.13 12.5 0.1 0.18 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) zinc_ribbon_2 PF13240.6 KPI35794.1 - 1.1 9.0 6.9 2.4 8.0 6.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF2259 PF10016.9 KPI35795.1 - 1.2 9.1 3.5 1.8 8.5 0.3 2.1 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) INCENP_ARK-bind PF03941.15 KPI35796.1 - 2.9e-18 65.5 2.0 1.3e-17 63.5 2.0 2.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ERM PF00769.19 KPI35796.1 - 0.0002 21.3 25.2 0.0002 21.3 25.2 3.3 4 0 0 4 4 4 2 Ezrin/radixin/moesin family Claudin_2 PF13903.6 KPI35797.1 - 2.5e-05 24.1 0.2 8.1e-05 22.5 0.3 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KPI35797.1 - 0.032 14.1 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Amastin surface glycoprotein Claudin_3 PF06653.11 KPI35797.1 - 0.1 12.6 2.7 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like DUF2776 PF10951.8 KPI35797.1 - 0.13 11.5 0.1 0.13 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2776) Caveolin PF01146.17 KPI35797.1 - 0.44 10.5 4.2 12 5.9 0.1 2.2 2 0 0 2 2 2 0 Caveolin VirB3 PF05101.13 KPI35797.1 - 0.51 10.6 3.0 3.9 7.8 0.1 2.7 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein COG7 PF10191.9 KPI35798.1 - 0.14 10.3 0.0 7.2 4.7 0.0 2.0 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) adh_short PF00106.25 KPI35799.1 - 5e-13 49.0 0.0 1.2e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI35799.1 - 2.9e-07 30.6 0.0 4.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI35799.1 - 7.8e-05 22.3 0.0 0.001 18.7 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase eIF-5_eIF-2B PF01873.17 KPI35800.1 - 3e-41 140.0 0.2 4.8e-41 139.3 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.10 KPI35800.1 - 0.027 14.8 1.5 1.6 9.2 0.0 2.9 3 0 0 3 3 3 0 Archaeal TRASH domain zf-HYPF PF07503.12 KPI35800.1 - 0.076 12.8 1.6 5.3 6.9 0.1 2.8 3 0 0 3 3 3 0 HypF finger GET2 PF08690.10 KPI35800.1 - 1.7 8.2 6.8 2.8 7.6 6.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 PARP PF00644.20 KPI35801.1 - 5.7e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KPI35801.1 - 9.1e-06 25.4 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Voldacs PF03517.13 KPI35801.1 - 0.22 11.7 1.5 1.9 8.6 0.4 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling FAA_hydrolase PF01557.18 KPI35804.1 - 3.1e-52 177.4 0.0 5.4e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Histone_HNS PF00816.21 KPI35805.1 - 0.035 14.9 3.9 0.12 13.2 3.9 1.9 1 0 0 1 1 1 0 H-NS histone family UCH PF00443.29 KPI35806.1 - 5.6e-08 32.6 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI35806.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase GATA PF00320.27 KPI35806.1 - 0.86 9.3 13.1 0.68 9.6 5.2 3.0 2 0 0 2 2 2 0 GATA zinc finger zf-AD PF07776.15 KPI35806.1 - 3.2 8.1 6.3 0.61 10.4 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Piwi PF02171.17 KPI35807.1 - 3.3e-47 161.2 0.0 5.2e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KPI35807.1 - 0.00026 21.2 0.3 0.00076 19.7 0.3 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 KPI35807.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KPI35807.1 - 0.0021 18.4 0.0 0.0083 16.4 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 KPI35807.1 - 0.054 14.1 0.5 0.26 11.9 0.2 2.4 2 1 0 2 2 2 0 N-terminal domain of argonaute SR-25 PF10500.9 KPI35807.1 - 0.74 9.4 14.6 1.4 8.4 14.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 KPI35807.1 - 5.5 5.1 8.0 8.2 4.6 8.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) U79_P34 PF03064.16 KPI35807.1 - 6.2 6.1 9.8 13 5.0 9.8 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.8 KPI35807.1 - 7.5 5.3 11.5 12 4.7 11.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mpv17_PMP22 PF04117.12 KPI35808.1 - 1.4e-14 54.1 0.1 3.4e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Acetyltransf_1 PF00583.25 KPI35809.1 - 1.4e-07 31.7 0.1 2.8e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI35809.1 - 0.00064 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI35809.1 - 0.0092 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI35809.1 - 0.052 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KPI35810.1 - 1.6e-59 197.8 2.9 2.2e-19 69.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CD52 PF15116.6 KPI35810.1 - 0.063 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen Cyclase PF04199.13 KPI35812.1 - 2e-14 54.0 0.0 2.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.16 KPI35813.1 - 4e-24 85.2 19.3 4.5e-20 71.9 19.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PITH PF06201.13 KPI35814.1 - 1.4e-42 145.5 0.0 1.8e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain UBA_4 PF14555.6 KPI35814.1 - 0.044 13.6 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain Septin PF00735.18 KPI35815.1 - 5e-113 377.1 0.4 5.9e-113 376.8 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KPI35815.1 - 3.1e-08 33.7 0.0 5.9e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI35815.1 - 2.8e-06 27.0 0.3 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KPI35815.1 - 3.2e-06 26.6 0.0 5.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KPI35815.1 - 3.9e-06 26.9 0.2 3.9e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KPI35815.1 - 0.00044 20.3 0.5 0.57 10.2 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 KPI35815.1 - 0.0022 17.5 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KPI35815.1 - 0.0039 17.5 0.0 0.0078 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI35815.1 - 0.0065 16.9 0.0 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KPI35815.1 - 0.0097 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KPI35815.1 - 0.019 15.4 0.4 0.043 14.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 KPI35815.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KPI35815.1 - 0.048 12.8 0.7 0.29 10.2 0.3 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Ras PF00071.22 KPI35815.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Ras family FtsK_SpoIIIE PF01580.18 KPI35815.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 KPI35815.1 - 0.061 13.3 0.3 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Microtubule binding AAA_23 PF13476.6 KPI35815.1 - 0.13 12.8 0.3 0.22 12.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPI35815.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC45 PF02724.14 KPI35816.1 - 6.5e-231 768.1 8.8 8.4e-230 764.4 8.8 3.2 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 KPI35816.1 - 0.015 14.6 41.7 0.25 10.7 16.1 2.2 2 0 0 2 2 2 0 BUD22 DUF4604 PF15377.6 KPI35816.1 - 0.2 12.1 25.7 0.1 13.1 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Nop14 PF04147.12 KPI35816.1 - 0.3 9.2 32.4 0.42 8.8 10.3 2.1 2 0 0 2 2 2 0 Nop14-like family Zip PF02535.22 KPI35816.1 - 1.9 7.6 11.4 0.44 9.7 1.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter SDA1 PF05285.12 KPI35816.1 - 2.6 7.4 36.0 0.79 9.1 12.7 2.3 2 0 0 2 2 2 0 SDA1 FAM60A PF15396.6 KPI35816.1 - 6.6 6.7 13.8 0.21 11.6 4.0 2.4 2 0 0 2 2 2 0 Protein Family FAM60A NACHT PF05729.12 KPI35818.1 - 4.7e-05 23.4 0.0 0.00036 20.5 0.0 2.3 1 1 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KPI35818.1 - 0.0016 19.0 0.2 0.064 13.9 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KPI35818.1 - 0.0023 18.4 0.2 0.011 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank_4 PF13637.6 KPI35818.1 - 0.0092 16.5 0.0 0.36 11.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) NB-ARC PF00931.22 KPI35818.1 - 0.017 14.3 0.0 0.31 10.2 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_22 PF13401.6 KPI35818.1 - 0.019 15.2 0.0 0.077 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 KPI35819.1 - 1.8e-08 34.3 9.7 1.8e-08 34.3 9.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ExoD PF06055.12 KPI35819.1 - 0.078 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Rabaptin PF03528.15 KPI35820.1 - 0.062 12.0 0.2 0.13 10.9 0.2 1.4 1 0 0 1 1 1 0 Rabaptin BRE1 PF08647.11 KPI35820.1 - 0.074 13.1 0.2 0.23 11.6 0.2 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TFIIA PF03153.13 KPI35820.1 - 4.7 7.1 6.7 0.99 9.3 3.3 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exo5 PF09810.9 KPI35821.1 - 6.5e-133 443.8 0.0 8e-133 443.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KPI35821.1 - 6.9e-05 22.9 0.2 0.31 10.9 0.0 3.1 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily HTH_18 PF12833.7 KPI35821.1 - 0.061 13.6 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3799 PF12684.7 KPI35821.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) MFS_1 PF07690.16 KPI35822.1 - 1.3e-38 132.8 41.8 1.3e-38 132.8 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35822.1 - 1.4e-09 37.4 8.9 1.4e-09 37.4 8.9 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KPI35822.1 - 0.015 13.6 10.2 0.034 12.4 10.2 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Dabb PF07876.12 KPI35823.1 - 2.1e-18 66.7 0.0 2.4e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldose_epim PF01263.20 KPI35826.1 - 7.9e-62 209.3 0.3 9.3e-62 209.0 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PIN_8 PF18476.1 KPI35827.1 - 0.0046 16.8 0.4 0.0046 16.8 0.4 6.9 7 2 1 8 8 8 1 PIN like domain Cep57_MT_bd PF06657.13 KPI35827.1 - 0.029 14.8 15.1 3.8 8.0 0.1 7.0 5 1 1 6 6 6 0 Centrosome microtubule-binding domain of Cep57 Dict-STAT-coil PF09267.10 KPI35827.1 - 1.7 9.0 5.1 1.4 9.3 1.8 2.6 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil M PF02370.16 KPI35827.1 - 1.8 9.4 3.6 79 4.4 0.0 3.6 2 1 1 3 3 3 0 M protein repeat bZIP_1 PF00170.21 KPI35827.1 - 8.5 6.6 15.4 2.2 8.4 0.6 4.9 4 1 1 5 5 5 0 bZIP transcription factor Fasciclin PF02469.22 KPI35828.1 - 2.8e-17 63.1 0.0 2.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.10 KPI35828.1 - 0.00067 19.0 0.7 0.0013 18.1 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.16 KPI35829.1 - 2.3e-35 122.2 14.0 2.3e-35 122.2 14.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_L27e PF01777.18 KPI35830.1 - 5.4e-38 129.2 5.6 8.1e-38 128.7 5.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KPI35830.1 - 0.0079 16.1 0.9 0.024 14.6 0.9 1.9 1 0 0 1 1 1 1 KOW motif Keratin_2_head PF16208.5 KPI35831.1 - 0.11 12.7 5.6 0.14 12.3 5.6 1.2 1 0 0 1 1 1 0 Keratin type II head Mpv17_PMP22 PF04117.12 KPI35832.1 - 1.9e-17 63.3 2.2 3.7e-17 62.3 2.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family UQ_con PF00179.26 KPI35833.1 - 5.7e-42 142.7 0.0 6.4e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Guanylate_kin PF00625.21 KPI35834.1 - 4.8e-55 186.0 0.0 6.4e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 KPI35834.1 - 2.1e-06 27.9 0.1 1.8e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPI35834.1 - 9.5e-06 25.5 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPI35834.1 - 6.8e-05 23.4 0.2 0.00039 21.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI35834.1 - 7.9e-05 23.1 0.1 0.00017 22.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPI35834.1 - 0.00034 20.6 0.0 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KPI35834.1 - 0.00041 20.6 0.0 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPI35834.1 - 0.00063 20.0 0.0 0.0015 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPI35834.1 - 0.0019 18.6 0.1 0.012 16.0 0.1 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KPI35834.1 - 0.0049 17.4 0.1 0.012 16.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KPI35834.1 - 0.005 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KPI35834.1 - 0.009 16.4 0.0 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 KPI35834.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KPI35834.1 - 0.012 15.3 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KPI35834.1 - 0.029 14.4 0.3 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KPI35834.1 - 0.029 14.3 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KPI35834.1 - 0.056 13.5 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KPI35834.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KPI35834.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KPI35834.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KPI35836.1 - 1.9e-33 115.9 30.8 1.9e-33 115.9 30.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KPI35837.1 - 1e-35 123.3 23.7 1.8e-35 122.5 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CD34_antigen PF06365.12 KPI35838.1 - 0.0021 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM51 PF15345.6 KPI35838.1 - 0.009 15.9 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 SKG6 PF08693.10 KPI35838.1 - 0.085 12.3 0.2 0.19 11.2 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 KPI35838.1 - 0.096 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Mid2 PF04478.12 KPI35838.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 KPI35838.1 - 0.37 10.8 1.5 0.68 9.9 1.5 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PRP38_assoc PF12871.7 KPI35838.1 - 0.87 10.2 14.9 1.9 9.2 14.9 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Lactonase PF10282.9 KPI35839.1 - 4.9e-60 203.6 0.0 6e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Oxidored_molyb PF00174.19 KPI35841.1 - 4.6e-53 179.3 0.0 7.8e-53 178.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KPI35841.1 - 2.1e-32 112.0 0.0 4.6e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KPI35841.1 - 1.7e-19 70.5 0.0 8.2e-19 68.3 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPI35841.1 - 8.7e-18 64.5 0.0 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KPI35841.1 - 1e-15 57.6 0.0 2.7e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KPI35841.1 - 0.1 12.7 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HSP20 PF00011.21 KPI35842.1 - 2e-11 44.0 0.0 2.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Methyltransf_23 PF13489.6 KPI35843.1 - 1.4e-15 57.5 0.4 1.5e-14 54.2 0.4 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI35843.1 - 0.00023 21.8 0.0 0.00089 19.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI35843.1 - 0.0051 17.4 0.0 0.01 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain BolA PF01722.18 KPI35843.1 - 0.084 13.2 0.8 5 7.5 0.0 3.1 3 0 0 3 3 3 0 BolA-like protein zf-C2H2 PF00096.26 KPI35845.1 - 0.0012 19.1 11.2 0.026 15.0 1.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI35845.1 - 0.016 16.0 6.2 0.45 11.5 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Sfi1 PF08457.10 KPI35846.1 - 1.3e-11 43.8 57.1 9.6e-06 24.4 18.2 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein Cas_DxTHG PF09455.10 KPI35846.1 - 0.26 10.8 4.2 0.25 10.9 3.1 1.4 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Glyco_transf_22 PF03901.17 KPI35848.1 - 1.6e-65 222.0 21.4 4.4e-39 134.9 4.5 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Snf7 PF03357.21 KPI35849.1 - 3.6e-33 114.6 4.5 3.6e-33 114.6 4.5 1.3 2 0 0 2 2 2 1 Snf7 Pyr_redox_2 PF07992.14 KPI35850.1 - 3.3e-65 220.2 5.7 3.3e-65 220.2 5.7 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KPI35850.1 - 4.5e-39 133.1 0.3 4.5e-39 133.1 0.3 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KPI35850.1 - 1.4e-20 73.6 0.9 1.4e-20 73.6 0.9 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI35850.1 - 1.5e-07 30.9 8.3 1.9e-05 23.9 4.1 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI35850.1 - 1.7e-07 30.8 0.1 1.7e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI35850.1 - 3.5e-07 29.7 0.4 0.01 15.0 0.1 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI35850.1 - 4.9e-07 29.9 2.9 0.026 14.8 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI35850.1 - 3e-06 26.9 0.4 3e-06 26.9 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI35850.1 - 9.9e-05 21.6 9.7 0.00011 21.4 1.8 3.0 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPI35850.1 - 0.00011 21.5 5.1 0.0031 16.8 0.5 3.2 3 1 1 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPI35850.1 - 0.00012 21.0 12.1 0.042 12.6 1.0 4.1 4 0 0 4 4 4 3 HI0933-like protein 3HCDH_N PF02737.18 KPI35850.1 - 0.02 14.8 0.8 0.056 13.3 0.8 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KPI35850.1 - 0.02 13.9 2.6 0.36 9.8 0.2 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 KPI35850.1 - 0.048 13.3 11.1 1.1 8.8 1.4 4.0 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPI35850.1 - 0.26 10.5 11.1 4.9 6.3 0.7 3.8 3 1 0 3 3 3 0 FAD binding domain adh_short_C2 PF13561.6 KPI35851.1 - 2.5e-50 171.2 0.0 3e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI35851.1 - 6.9e-45 152.9 0.0 9.2e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI35851.1 - 3.3e-06 27.1 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI35851.1 - 9e-05 22.0 0.1 0.0029 17.0 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI35851.1 - 0.0047 16.4 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CENP-Q PF13094.6 KPI35852.1 - 0.11 12.7 1.9 0.27 11.4 1.9 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-CCCH PF00642.24 KPI35852.1 - 0.21 11.6 3.2 0.5 10.3 3.2 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAC4 PF16093.5 KPI35853.1 - 0.15 12.2 0.9 0.69 10.1 0.1 2.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 PAS_12 PF18095.1 KPI35854.1 - 0.043 13.5 0.2 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Lactonase PF10282.9 KPI35855.1 - 1.9e-16 60.3 0.0 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KPI35855.1 - 0.00028 20.6 0.0 0.00075 19.2 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DEAD PF00270.29 KPI35856.1 - 3.1e-46 157.3 0.1 5e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI35856.1 - 3e-19 69.4 0.0 4.9e-18 65.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI35856.1 - 4.9e-05 23.4 0.0 8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPI35856.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NAD_binding_10 PF13460.6 KPI35857.1 - 1.2e-14 54.7 0.0 1.7e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI35857.1 - 0.0059 16.1 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPI35857.1 - 0.015 14.9 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.24 KPI35857.1 - 0.086 13.3 0.0 0.18 12.3 0.0 1.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TBP PF00352.21 KPI35858.1 - 1.2e-66 220.6 0.1 4e-32 110.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KPI35858.1 - 5e-05 23.3 0.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KPI35858.1 - 0.036 13.9 0.1 0.21 11.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) zf-MYND PF01753.18 KPI35859.1 - 6.6e-13 48.5 7.7 1.1e-12 47.8 7.7 1.4 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.6 KPI35859.1 - 0.047 13.1 1.2 0.14 11.6 1.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain MYO10_CC PF16735.5 KPI35860.1 - 0.015 15.4 0.5 0.042 14.0 0.5 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Zn_clus PF00172.18 KPI35861.1 - 9.3e-09 35.3 13.4 1.4e-08 34.7 13.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-T_C PF15511.6 KPI35862.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KPI35862.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KPI35862.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KPI35862.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KPI35862.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KPI35862.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KPI35862.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KPI35862.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KPI35862.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 KPI35862.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Cutinase PF01083.22 KPI35863.1 - 3.3e-50 170.5 4.5 3.8e-50 170.3 4.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPI35863.1 - 7.9e-07 28.9 0.3 1.1e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain Palm_thioest PF02089.15 KPI35863.1 - 0.069 13.0 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 KPI35863.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Vint PF14623.6 KPI35864.1 - 2.6e-53 180.3 0.0 1.2e-52 178.1 0.0 1.9 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 KPI35864.1 - 6.1e-21 74.3 0.0 1.5e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KPI35864.1 - 2.2e-14 54.1 0.0 3.9e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPI35864.1 - 5.6e-11 43.0 0.0 2.1e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KPI35864.1 - 4e-07 30.1 0.0 2.1e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain Sec61_beta PF03911.16 KPI35865.1 - 0.094 12.8 0.2 0.094 12.8 0.2 2.1 2 0 0 2 2 2 0 Sec61beta family Arylsulfotrans PF05935.11 KPI35866.1 - 3.9e-20 72.1 0.0 1e-07 31.2 0.0 3.3 1 1 2 3 3 3 3 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 KPI35866.1 - 4.4e-16 59.1 0.0 1e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 KPI35866.1 - 1e-05 25.3 0.0 3.2e-05 23.7 0.0 1.8 2 1 1 3 3 3 2 PQQ-like domain Syd PF07348.12 KPI35868.1 - 0.029 14.0 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 Syd protein (SUKH-2) TAP35_44 PF07265.11 KPI35868.1 - 1.1 9.3 3.3 0.67 10.0 0.3 1.9 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 Fungal_trans PF04082.18 KPI35869.1 - 1.1e-14 54.1 0.0 1.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lum_binding PF00677.17 KPI35870.1 - 1.3e-44 150.0 1.2 6e-22 77.4 0.8 2.4 2 1 0 2 2 2 2 Lumazine binding domain MFS_1 PF07690.16 KPI35872.1 - 9.7e-34 116.8 27.0 1.5e-33 116.2 27.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 KPI35872.1 - 0.011 16.1 0.4 0.011 16.1 0.4 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AB DUF3671 PF12420.8 KPI35872.1 - 0.02 15.0 1.2 0.18 11.9 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function Vir_act_alpha_C PF10400.9 KPI35872.1 - 0.21 12.3 0.2 8.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term A_deaminase PF00962.22 KPI35873.1 - 3e-45 155.0 0.0 1.1e-44 153.1 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 KPI35873.1 - 0.0025 17.4 0.1 0.0048 16.4 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPI35873.1 - 0.017 14.4 0.3 0.14 11.5 0.1 2.3 2 1 1 3 3 3 0 Amidohydrolase family Mito_carr PF00153.27 KPI35875.1 - 5.9e-51 170.4 3.5 2.3e-21 75.5 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF4834 PF16118.5 KPI35876.1 - 0.041 14.9 0.0 0.07 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Amnionless PF14828.6 KPI35876.1 - 0.17 10.7 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless Rax2 PF12768.7 KPI35876.1 - 0.19 11.1 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4690 PF15756.5 KPI35876.1 - 0.95 10.1 3.5 0.7 10.5 1.1 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage E1_dh PF00676.20 KPI35878.1 - 2.7e-17 62.7 0.1 3.8e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component SWIRM-assoc_1 PF16495.5 KPI35879.1 - 0.34 10.9 11.7 5.1 7.1 1.9 2.7 1 1 1 2 2 2 0 SWIRM-associated region 1 ADIP PF11559.8 KPI35879.1 - 1.3 9.1 19.0 4.9 7.2 5.6 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KPI35879.1 - 6.6 6.8 17.6 8.1 6.5 7.2 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KPI35879.1 - 8.2 7.0 25.7 11 6.5 2.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region NPR2 PF06218.11 KPI35880.1 - 1e-97 327.7 0.0 5.5e-73 246.2 0.0 2.7 1 1 1 2 2 2 2 Nitrogen permease regulator 2 GST_N_3 PF13417.6 KPI35881.1 - 3.6e-08 33.7 0.0 6.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI35881.1 - 1.6e-06 28.3 0.0 8.7e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI35881.1 - 8.9e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI35881.1 - 0.00028 21.1 0.0 0.00067 19.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KPI35881.1 - 0.00052 20.6 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI35881.1 - 0.0063 16.5 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mcl1_mid PF12341.8 KPI35882.1 - 5e-88 295.3 0.0 6e-87 291.7 0.0 2.4 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KPI35882.1 - 2.1e-15 56.8 0.1 0.00026 21.2 0.0 4.6 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI35882.1 - 3.2e-14 53.1 1.4 7.1e-06 26.7 0.1 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat VID27 PF08553.10 KPI35882.1 - 0.00036 19.7 0.0 0.00069 18.8 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KPI35882.1 - 0.0026 16.8 0.0 0.06 12.3 0.0 2.4 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KPI35882.1 - 0.052 13.5 0.6 16 5.5 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KPI35882.1 - 0.084 10.9 0.0 0.14 10.2 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Clathrin PF00637.20 KPI35883.1 - 3.1e-16 59.5 1.3 1.2e-14 54.4 0.2 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KPI35883.1 - 0.07 13.6 0.0 0.34 11.4 0.0 2.1 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_7 PF13176.6 KPI35883.1 - 0.09 12.8 0.8 0.53 10.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI35883.1 - 0.21 11.8 0.3 1.2 9.4 0.3 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI35883.1 - 0.61 10.4 5.3 0.56 10.5 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CCDC106 PF15794.5 KPI35884.1 - 0.029 14.1 0.0 0.083 12.6 0.0 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 KPI35884.1 - 7.7 6.3 11.6 0.58 10.0 1.1 2.6 2 0 0 2 2 2 0 SPX domain MAPEG PF01124.18 KPI35885.1 - 7.7e-13 48.5 3.2 9e-13 48.3 3.2 1.1 1 0 0 1 1 1 1 MAPEG family AhpC-TSA_2 PF13911.6 KPI35886.1 - 5.6e-15 55.4 0.0 1.3e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme polyprenyl_synt PF00348.17 KPI35887.1 - 1.8e-65 220.5 0.0 2.2e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 KPI35887.1 - 0.076 13.0 0.1 0.27 11.2 0.0 1.8 1 1 0 2 2 2 0 Translin family Cpn60_TCP1 PF00118.24 KPI35888.1 - 6.3e-85 285.7 13.6 1.2e-84 284.8 13.6 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 KPI35888.1 - 0.071 13.5 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator Fungal_trans_2 PF11951.8 KPI35889.1 - 1.7e-08 33.7 2.6 7.6e-06 25.0 0.1 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35889.1 - 2e-05 24.6 11.5 2e-05 24.6 11.5 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.20 KPI35890.1 - 2.2e-119 399.0 1.0 5e-117 391.3 0.5 2.1 2 0 0 2 2 2 2 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KPI35890.1 - 8e-07 28.7 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KPI35890.1 - 9.1e-06 25.8 0.0 7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain DUF2761 PF10959.8 KPI35890.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Pyridoxal_deC PF00282.19 KPI35891.1 - 7.5e-79 265.1 0.0 1.1e-78 264.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA_2 PF07724.14 KPI35892.1 - 3.5e-39 134.6 0.0 4.8e-38 130.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KPI35892.1 - 9.2e-15 55.2 0.0 1.8e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPI35892.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KPI35892.1 - 6.8e-06 26.1 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 KPI35892.1 - 9.1e-05 21.9 0.1 0.01 15.2 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KPI35892.1 - 0.00028 20.6 0.2 0.077 12.7 0.0 2.9 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 KPI35892.1 - 0.002 18.4 0.3 0.028 14.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPI35892.1 - 0.0037 17.0 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KPI35892.1 - 0.0043 17.5 0.9 0.012 16.0 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 KPI35892.1 - 0.0049 16.6 0.1 0.09 12.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KPI35892.1 - 0.0053 16.5 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 KPI35892.1 - 0.0072 15.4 0.2 0.018 14.1 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain AAA_7 PF12775.7 KPI35892.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPI35892.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KPI35892.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KPI35892.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPI35892.1 - 0.16 12.1 0.5 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI35892.1 - 0.19 12.3 1.5 0.26 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.23 KPI35893.1 - 4.2e-15 55.5 0.0 5.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPI35893.1 - 4.4e-11 42.9 0.0 5.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Amidase PF01425.21 KPI35894.1 - 8.2e-73 245.9 0.0 1e-54 186.3 0.0 2.9 2 1 1 3 3 3 2 Amidase GFO_IDH_MocA PF01408.22 KPI35895.1 - 2.1e-25 89.8 0.0 3.3e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI35895.1 - 8.9e-10 38.6 0.2 3.4e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 KPI35895.1 - 0.0018 18.5 0.2 0.0078 16.5 0.2 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KPI35895.1 - 0.013 15.7 0.1 0.029 14.6 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KPI35895.1 - 0.028 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPI35895.1 - 0.045 13.9 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PetL PF05115.14 KPI35896.1 - 0.11 12.4 0.6 0.11 12.4 0.6 2.9 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) Dehydratase_hem PF13816.6 KPI35897.1 - 3.4e-80 269.7 0.0 6.3e-51 173.6 0.0 2.1 2 0 0 2 2 2 2 Haem-containing dehydratase DUF4188 PF13826.6 KPI35897.1 - 1.6e-06 28.4 0.0 0.00016 22.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) DUF2007 PF09413.10 KPI35898.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Cyd_oper_YbgE PF09600.10 KPI35898.1 - 0.042 14.2 0.2 0.075 13.4 0.2 1.3 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF155 PF02582.14 KPI35899.1 - 7.9e-43 146.6 0.0 1.1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_2b PF00587.25 KPI35900.1 - 2.5e-20 73.2 0.0 5.4e-20 72.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sec34 PF04136.15 KPI35900.1 - 0.056 13.3 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Sec34-like family DUF1366 PF07104.11 KPI35900.1 - 0.11 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Vps4_C PF09336.10 KPI35900.1 - 0.15 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PTCB-BRCT PF12738.7 KPI35901.1 - 0.00037 20.4 0.1 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 KPI35901.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KPI35901.1 - 0.019 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FAD_binding_3 PF01494.19 KPI35902.1 - 5.7e-16 58.7 1.6 1.5e-08 34.3 0.1 3.7 3 2 1 4 4 4 3 FAD binding domain SE PF08491.10 KPI35902.1 - 0.0011 18.1 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.24 KPI35902.1 - 0.022 14.3 1.1 0.52 9.8 0.0 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI35902.1 - 0.025 14.8 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 KPI35904.1 - 3.7e-24 85.3 29.4 3.7e-24 85.3 29.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1240 PF06836.12 KPI35904.1 - 0.33 11.5 2.0 0.79 10.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) MaoC_dehydratas PF01575.19 KPI35906.1 - 1.1e-25 89.6 0.0 2.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KPI35906.1 - 7.1e-15 55.3 0.3 2.8e-06 27.5 0.1 2.1 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Alpha-amylase_C PF02806.18 KPI35907.1 - 1.1e-25 89.9 0.0 2.7e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KPI35907.1 - 1e-18 67.4 0.0 4e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KPI35907.1 - 2.9e-17 63.3 0.1 3e-13 50.0 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPI35907.1 - 0.067 12.3 0.2 0.15 11.2 0.1 1.5 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain PepX_C PF08530.10 KPI35908.1 - 2.1e-38 132.5 0.1 3e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KPI35908.1 - 3.6e-37 128.4 0.0 5.4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Epimerase PF01370.21 KPI35912.1 - 0.00094 18.7 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI35912.1 - 0.061 12.5 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 KPI35912.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KPI35913.1 - 5.8e-07 28.8 6.6 8.1e-07 28.3 6.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CarS-like PF01864.17 KPI35913.1 - 0.011 15.7 0.2 0.011 15.7 0.2 1.7 2 0 0 2 2 2 0 CDP-archaeol synthase Sugar_tr PF00083.24 KPI35914.1 - 4.2e-84 283.0 23.7 5.3e-84 282.7 23.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35914.1 - 1.6e-27 96.4 23.9 1.6e-27 96.4 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KPI35914.1 - 3.8e-05 22.8 1.7 3.8e-05 22.8 1.7 2.3 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Aldedh PF00171.22 KPI35916.1 - 6.6e-122 407.3 6.2 1.5e-119 399.5 6.2 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI35916.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) ISG65-75 PF11727.8 KPI35916.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4607 PF15380.6 KPI35916.1 - 0.17 11.3 0.1 0.34 10.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) DHquinase_I PF01487.15 KPI35917.1 - 5.7e-22 79.1 0.0 8.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KPI35917.1 - 6.3e-17 61.6 0.0 1.6e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KPI35917.1 - 3.3e-12 46.8 0.0 6.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 KPI35917.1 - 5.5e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.7 KPI35918.1 - 3.4e-19 70.3 1.0 4.3e-19 70.0 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI35918.1 - 6.4e-16 58.8 0.3 1.8e-15 57.3 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI35918.1 - 7.6e-13 48.3 0.1 1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KPI35918.1 - 4.7e-05 23.2 0.0 0.00013 21.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KPI35918.1 - 0.0034 17.1 0.1 0.0079 15.9 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 KPI35918.1 - 0.026 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KPI35918.1 - 0.058 12.6 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KPI35918.1 - 0.082 13.0 0.4 0.13 12.4 0.4 1.8 1 1 0 1 1 1 0 Thioesterase domain DUF2920 PF11144.8 KPI35918.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KPI35919.1 - 5e-10 39.5 0.1 2.1e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI35919.1 - 1.9e-09 38.5 0.0 2.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI35919.1 - 4.1e-08 32.8 0.0 3.4e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KPI35919.1 - 0.0024 17.5 0.2 0.0059 16.2 0.1 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family PhoPQ_related PF10142.9 KPI35919.1 - 0.014 14.1 0.1 0.024 13.3 0.1 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.10 KPI35919.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KPI35919.1 - 0.024 14.3 0.2 0.33 10.6 0.2 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KPI35919.1 - 0.17 11.8 0.0 0.95 9.3 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal HET PF06985.11 KPI35920.1 - 2.7e-23 82.9 0.1 6.7e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.12 KPI35921.1 - 1.8e-07 31.0 0.0 3.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI35921.1 - 2.6e-07 30.7 0.2 4.3e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI35921.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase HeLo PF14479.6 KPI35922.1 - 2.3e-13 50.4 3.6 3e-10 40.3 0.1 3.1 2 1 1 3 3 3 2 Prion-inhibition and propagation NACHT PF05729.12 KPI35922.1 - 1.3e-05 25.1 0.1 3.8e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPI35922.1 - 0.00055 20.4 1.2 0.0018 18.7 0.1 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI35922.1 - 0.0012 19.1 0.1 0.0077 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KPI35922.1 - 0.03 13.5 0.0 1.3 8.1 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain PIF1 PF05970.14 KPI35922.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase E1-E2_ATPase PF00122.20 KPI35924.1 - 2.7e-48 163.9 0.0 8.9e-48 162.2 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KPI35924.1 - 4.8e-29 102.2 0.6 1.1e-23 84.6 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 KPI35924.1 - 8.9e-17 61.3 0.9 4.4e-10 39.9 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KPI35924.1 - 0.00013 21.8 0.0 0.016 15.0 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase FlgD_ig PF13860.6 KPI35924.1 - 0.058 13.3 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 FlgD Ig-like domain Fer2_4 PF13510.6 KPI35924.1 - 0.086 12.9 0.4 0.33 11.0 0.4 2.0 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF3431 PF11913.8 KPI35925.1 - 4.1e-78 262.1 1.7 4.9e-78 261.8 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) IGPS PF00218.21 KPI35926.1 - 4.9e-94 314.2 0.0 7.3e-94 313.7 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KPI35926.1 - 2.1e-45 154.9 0.0 3.5e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KPI35926.1 - 1.2e-44 152.5 0.0 2.6e-41 141.6 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KPI35926.1 - 0.00016 21.5 0.4 0.00048 19.9 0.4 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KPI35926.1 - 0.00082 19.2 0.1 0.13 12.0 0.1 2.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 KPI35926.1 - 0.02 14.1 1.1 1.4 8.1 0.1 3.1 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KPI35926.1 - 0.026 14.0 0.6 0.43 10.0 0.1 2.9 4 0 0 4 4 4 0 Histidine biosynthesis protein TMP-TENI PF02581.17 KPI35926.1 - 0.11 11.8 0.3 61 2.9 0.0 3.8 4 0 0 4 4 4 0 Thiamine monophosphate synthase Alpha-L-AF_C PF06964.12 KPI35927.1 - 3.8e-29 102.0 0.2 5.4e-29 101.5 0.2 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain ProQ_C PF17516.2 KPI35927.1 - 0.04 13.3 0.2 0.073 12.5 0.2 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain Peptidase_S10 PF00450.22 KPI35928.1 - 6.8e-129 430.9 0.1 8e-129 430.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KPI35928.1 - 2.8e-15 57.0 0.0 5.6e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide ADH_N PF08240.12 KPI35929.1 - 1.6e-27 95.5 1.7 2.5e-27 94.9 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI35929.1 - 3.5e-20 72.3 0.2 5.6e-20 71.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI35929.1 - 2.3e-05 25.5 0.1 4.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI35929.1 - 0.00068 19.0 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KPI35929.1 - 0.081 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CAP_N PF01213.19 KPI35931.1 - 0.42 10.1 5.5 0.47 9.9 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KPI35931.1 - 0.5 10.4 8.9 0.54 10.3 8.9 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyoxalase PF00903.25 KPI35932.1 - 0.00015 21.9 0.0 0.00063 19.9 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MMU163 PF17119.5 KPI35933.1 - 3.5e-87 291.7 0.8 3.8e-53 180.2 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Peptidase_M24 PF00557.24 KPI35934.1 - 1.9e-54 184.6 0.4 2.8e-54 184.0 0.4 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KPI35934.1 - 3.8e-24 84.8 0.0 6.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain MFS_1 PF07690.16 KPI35936.1 - 2.1e-38 132.2 41.6 3e-38 131.6 41.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MMPL PF03176.15 KPI35936.1 - 0.11 11.4 8.8 0.013 14.5 3.6 1.9 2 0 0 2 2 2 0 MMPL family SAPS PF04499.15 KPI35937.1 - 0.9 8.3 14.3 1.2 7.8 14.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 KPI35937.1 - 2 8.4 3.1 2.6 8.1 3.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 KPI35937.1 - 6.4 7.4 8.5 55 4.4 8.1 2.2 1 1 0 1 1 1 0 Ctr copper transporter family FRG1 PF06229.12 KPI35938.1 - 9.6e-22 77.6 1.0 6.1e-21 75.0 0.1 2.4 2 1 0 2 2 2 1 FRG1-like domain PCNP PF15473.6 KPI35938.1 - 0.63 10.8 11.5 0.096 13.4 4.8 2.2 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family Fungal_trans PF04082.18 KPI35940.1 - 2.7e-10 39.7 1.5 4.1e-10 39.1 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_11 PF13086.6 KPI35941.1 - 1.2e-24 87.5 0.7 4.8e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KPI35941.1 - 7.8e-24 84.4 0.0 5.1e-20 72.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI35941.1 - 4e-07 29.9 0.0 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPI35941.1 - 1.6e-05 25.3 0.0 9.7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KPI35941.1 - 0.00067 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KPI35941.1 - 0.0011 18.3 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KPI35941.1 - 0.0042 16.8 0.0 0.47 10.2 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KPI35941.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 KPI35941.1 - 0.039 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KPI35941.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI35941.1 - 0.13 12.5 0.1 1 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KPI35941.1 - 0.14 12.6 0.2 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_47 PF01532.20 KPI35942.1 - 7.2e-156 519.6 0.0 8.5e-131 437.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 SMC_N PF02463.19 KPI35945.1 - 7.3e-23 81.1 0.0 7.1e-22 77.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPI35945.1 - 6.2e-17 62.8 0.6 6.2e-17 62.8 0.6 4.9 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KPI35945.1 - 1.3e-13 51.4 8.0 2.9e-13 50.3 3.9 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KPI35945.1 - 9e-07 29.0 0.1 0.00051 19.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPI35945.1 - 0.00052 19.7 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KPI35945.1 - 0.021 15.1 0.0 0.1 12.9 0.0 2.2 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KPI35945.1 - 0.57 10.7 14.5 0.99 9.9 0.1 5.0 4 2 0 4 4 4 0 ABC transporter Nup188_C PF18378.1 KPI35946.1 - 1.1e-61 208.7 0.0 1.9e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KPI35946.1 - 2.6e-41 141.5 0.0 1.5e-39 135.7 0.0 2.8 2 1 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 2-oxoacid_dh PF00198.23 KPI35947.1 - 4.4e-63 212.8 0.2 7.3e-63 212.1 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 KPI35947.1 - 2e-11 44.0 0.0 4.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain ADH_zinc_N PF00107.26 KPI35948.1 - 5.6e-21 74.9 0.0 7.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI35948.1 - 6.6e-06 26.4 0.1 9.2e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KPI35948.1 - 8.5e-06 25.4 0.1 2.6e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI35948.1 - 4.5e-05 24.5 0.0 6.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI35948.1 - 0.00028 20.3 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KPI35948.1 - 0.00029 20.2 0.7 0.00047 19.5 0.6 1.3 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KPI35948.1 - 0.00057 19.9 0.1 0.00082 19.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KPI35948.1 - 0.007 15.9 0.1 0.0087 15.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPI35948.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KPI35948.1 - 0.034 14.0 0.5 0.24 11.2 0.5 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KPI35948.1 - 0.034 14.8 0.7 0.12 13.1 0.7 2.1 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain XdhC_C PF13478.6 KPI35948.1 - 0.036 14.6 0.1 0.054 14.0 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 KPI35948.1 - 0.05 14.2 0.0 0.092 13.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KPI35948.1 - 0.066 12.6 2.1 0.091 12.1 0.7 1.8 2 0 0 2 2 2 0 ThiF family DFP PF04127.15 KPI35948.1 - 0.067 13.0 0.1 0.067 13.0 0.1 1.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Pyr_redox PF00070.27 KPI35948.1 - 0.076 13.6 0.1 0.17 12.5 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KPI35948.1 - 0.078 12.4 0.2 0.16 11.4 0.2 1.5 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KPI35948.1 - 0.093 12.9 0.9 1.3 9.1 0.9 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 KPI35948.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding HET PF06985.11 KPI35950.1 - 2.4e-17 63.7 0.0 6.1e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hyd_65N_2 PF14498.6 KPI35952.1 - 5.4e-59 199.9 1.3 2.4e-57 194.5 1.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain p450 PF00067.22 KPI35953.1 - 2.9e-51 174.7 0.0 4.8e-50 170.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Patatin PF01734.22 KPI35954.1 - 1.1e-18 68.2 0.0 3.5e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.6 KPI35954.1 - 0.0016 18.4 4.5 0.0016 18.4 4.5 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KPI35954.1 - 0.013 15.6 5.0 0.1 12.8 5.0 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KPI35954.1 - 0.015 15.1 5.1 0.042 13.7 5.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI35954.1 - 0.34 11.3 5.9 0.92 9.9 5.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KPI35954.1 - 0.77 9.8 8.7 0.24 11.5 5.0 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI35954.1 - 1.5 8.7 9.0 1.2 9.0 4.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI35954.1 - 4 7.4 9.9 2.1 8.3 5.7 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1445 PF07286.12 KPI35955.1 - 2.5e-57 192.8 0.0 5.1e-57 191.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) DUF4260 PF14079.6 KPI35957.1 - 2e-36 124.4 1.3 8.2e-36 122.4 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4260) Sas10 PF09368.10 KPI35958.1 - 1.7e-28 98.9 9.4 7.6e-28 96.8 9.4 2.2 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KPI35958.1 - 1.3e-09 38.6 0.1 6.7e-09 36.3 0.1 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Helo_like_N PF17111.5 KPI35958.1 - 0.026 13.9 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Zn_clus PF00172.18 KPI35959.1 - 0.0017 18.4 13.9 0.0028 17.7 13.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_dh_N PF08501.11 KPI35960.1 - 5e-15 55.5 0.0 8.8e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KPI35960.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI35960.1 - 0.0021 18.3 0.2 0.0035 17.6 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 KPI35960.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Tannase PF07519.11 KPI35961.1 - 1.8e-70 238.2 0.0 3.2e-70 237.4 0.0 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KPI35961.1 - 0.0039 16.7 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPI35961.1 - 0.015 14.6 0.0 0.077 12.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI35961.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold TRI12 PF06609.13 KPI35962.1 - 7.1e-36 123.8 28.2 9.5e-36 123.4 28.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI35962.1 - 5.7e-18 64.9 61.0 5.7e-18 64.9 61.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2417 PF10329.9 KPI35962.1 - 0.63 9.4 3.0 1.3 8.4 3.0 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) FAD_binding_3 PF01494.19 KPI35964.1 - 8.8e-100 334.3 0.0 1.1e-99 334.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI35964.1 - 6.8e-07 29.2 0.1 0.012 15.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI35964.1 - 4e-06 26.3 0.0 9.2e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI35964.1 - 0.00038 20.6 0.0 0.00085 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI35964.1 - 0.00087 18.5 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KPI35964.1 - 0.024 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KPI35964.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI35964.1 - 0.14 10.8 0.0 0.54 8.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KPI35964.1 - 0.16 12.5 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytochrom_B562 PF07361.11 KPI35965.1 - 0.67 10.6 10.4 1.4 9.6 10.4 1.5 1 0 0 1 1 1 0 Cytochrome b562 C1_4 PF07975.12 KPI35965.1 - 0.7 10.2 4.7 1.8 8.9 4.7 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain MutS_III PF05192.18 KPI35965.1 - 3.2 7.9 9.6 5.1 7.3 9.6 1.6 1 1 0 1 1 1 0 MutS domain III DUF4638 PF15472.6 KPI35965.1 - 3.9 7.1 10.3 5.7 6.6 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DEK_C PF08766.11 KPI35966.1 - 0.075 13.0 0.1 7.9 6.5 0.0 3.1 3 0 0 3 3 3 0 DEK C terminal domain Cation_ATPase_N PF00690.26 KPI35966.1 - 0.14 11.8 0.2 0.97 9.2 0.0 2.1 1 1 1 2 2 2 0 Cation transporter/ATPase, N-terminus Fungal_trans_2 PF11951.8 KPI35967.1 - 0.00014 20.8 0.7 0.00028 19.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain AP_endonuc_2 PF01261.24 KPI35968.1 - 9.1e-27 93.9 0.1 1.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ADH_zinc_N PF00107.26 KPI35969.1 - 6.7e-20 71.4 0.9 1.2e-19 70.6 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI35969.1 - 2e-06 28.9 0.0 3.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI35969.1 - 0.00015 21.6 0.0 0.0015 18.4 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KPI35969.1 - 0.0097 15.4 0.8 0.014 14.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase PHD PF00628.29 KPI35970.1 - 7.2e-08 32.2 14.5 1.3e-07 31.4 14.5 1.3 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KPI35970.1 - 0.0038 17.1 16.3 0.016 15.1 9.7 2.3 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_7 PF02591.15 KPI35970.1 - 0.037 14.2 3.4 0.84 9.9 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-RRPl_C4 PF17026.5 KPI35970.1 - 0.84 9.8 3.6 3.4 7.8 3.6 1.9 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE_2 PF02318.16 KPI35970.1 - 2.6 8.3 6.8 1.6 8.9 4.3 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.6 KPI35970.1 - 5.2 6.7 15.6 0.41 10.2 10.1 2.0 2 1 0 2 2 2 0 PHD-finger Mid2 PF04478.12 KPI35971.1 - 7.3e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KPI35971.1 - 3e-07 29.8 0.9 5.7e-07 28.8 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KPI35971.1 - 0.025 14.5 0.3 0.025 14.5 0.3 1.9 1 1 1 2 2 2 0 TMEM154 protein family Pap_E4 PF02711.14 KPI35971.1 - 0.11 13.5 6.1 5 8.2 1.0 2.3 2 0 0 2 2 2 0 E4 protein Mucin PF01456.17 KPI35971.1 - 0.73 9.8 18.1 0.05 13.6 11.7 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.11 KPI35971.1 - 1.4 9.4 9.5 0.13 12.7 3.8 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4690 PF15756.5 KPI35971.1 - 3.5 8.3 9.6 0.29 11.7 3.8 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage adh_short PF00106.25 KPI35972.1 - 1.3e-19 70.4 0.0 2.7e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35972.1 - 1.2e-10 41.4 0.0 3.4e-09 36.6 0.0 2.2 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI35972.1 - 4e-07 30.1 0.1 2.5e-05 24.3 0.0 2.2 1 1 1 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 KPI35972.1 - 0.00048 19.5 0.0 0.00077 18.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KPI35972.1 - 0.012 16.1 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 KPI35972.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase LRR_10 PF18805.1 KPI35972.1 - 0.073 12.7 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat 3HCDH_N PF02737.18 KPI35972.1 - 0.19 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gpr1_Fun34_YaaH PF01184.19 KPI35973.1 - 5.5e-22 78.4 24.8 1.5e-21 77.0 24.8 1.6 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family AMPK1_CBM PF16561.5 KPI35973.1 - 0.00018 21.7 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase MRAP PF15183.6 KPI35973.1 - 4.2 7.4 7.3 0.25 11.3 0.8 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Hydantoinase_B PF02538.14 KPI35974.1 - 4.7e-181 602.7 1.8 1.2e-180 601.3 1.8 1.6 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KPI35974.1 - 2.4e-63 214.1 0.1 8.2e-60 202.5 0.0 3.9 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KPI35974.1 - 2.1e-30 105.8 0.1 1.2e-21 77.2 0.0 3.5 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase N-terminal region AMP-binding PF00501.28 KPI35975.1 - 3.9e-71 239.9 0.0 5.1e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI35975.1 - 5.9e-12 46.4 0.0 1.3e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 KPI35976.1 - 7.4e-94 315.2 18.2 8.6e-94 314.9 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35976.1 - 4.5e-27 94.9 31.7 4.5e-27 94.9 31.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI35976.1 - 0.0001 20.9 2.0 0.00024 19.7 2.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI35977.1 - 1.9e-36 125.7 37.0 1.9e-36 125.7 37.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI35977.1 - 2.6e-14 52.9 13.5 2.6e-14 52.9 13.5 3.8 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 KPI35977.1 - 8.5e-07 27.8 5.8 1.5e-06 26.9 5.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KPI35977.1 - 1e-06 28.3 6.9 1e-06 28.3 6.9 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Gly-zipper_Omp PF13488.6 KPI35977.1 - 0.73 9.9 6.6 3.6 7.7 1.8 2.8 2 0 0 2 2 2 0 Glycine zipper zf-MYND PF01753.18 KPI35978.1 - 2.7e-07 30.6 7.9 5.6e-07 29.5 7.9 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KPI35978.1 - 0.0008 19.5 4.2 0.002 18.2 4.2 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 KbaA PF14089.6 KPI35978.1 - 0.029 14.2 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation F-box-like_2 PF13013.6 KPI35979.1 - 0.058 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain HET PF06985.11 KPI35980.1 - 1.2e-29 103.6 0.0 1.7e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_31 PF13847.6 KPI35981.1 - 4.8e-22 78.4 0.0 7.1e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI35981.1 - 1.3e-19 70.7 0.1 2.6e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI35981.1 - 6.7e-17 61.9 0.1 1.4e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI35981.1 - 1.8e-15 57.5 0.0 3.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI35981.1 - 7.5e-15 54.9 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KPI35981.1 - 7.2e-14 51.9 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPI35981.1 - 6.4e-09 35.9 0.0 2.2e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KPI35981.1 - 5.7e-07 29.8 0.0 1.8e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KPI35981.1 - 0.00019 21.0 0.0 0.0004 20.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KPI35981.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_19 PF04672.12 KPI35981.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_4 PF02390.17 KPI35981.1 - 0.17 11.3 0.0 1.9 7.9 0.0 2.4 3 0 0 3 3 3 0 Putative methyltransferase adh_short PF00106.25 KPI35982.1 - 1.9e-34 118.8 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI35982.1 - 4.2e-25 88.7 0.0 5.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KPI35982.1 - 1.6e-09 37.5 0.0 4.1e-09 36.2 0.1 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KPI35982.1 - 1.6e-08 34.7 0.2 3e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI35982.1 - 0.0004 19.9 0.3 0.0015 18.1 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI35982.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding BclA_C PF18573.1 KPI35982.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 BclA C-terminal domain RmlD_sub_bind PF04321.17 KPI35982.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.24 KPI35983.1 - 4.1e-103 345.7 22.2 4.7e-103 345.5 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI35983.1 - 2.4e-31 108.9 33.7 2.9e-24 85.6 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily T4BSS_DotH_IcmK PF12293.8 KPI35983.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion Gly-zipper_Omp PF13488.6 KPI35983.1 - 2.5 8.2 5.5 7.3 6.7 5.5 1.7 1 0 0 1 1 1 0 Glycine zipper Kinesin PF00225.23 KPI35984.1 - 3.2e-40 138.1 0.0 5.4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Mitofilin PF09731.9 KPI35984.1 - 1.1 8.0 7.3 1.5 7.6 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1 PF07690.16 KPI35985.1 - 9.3e-29 100.4 21.0 9.3e-29 100.4 21.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 KPI35985.1 - 9.4 5.9 20.6 0.35 10.6 0.5 3.8 4 0 0 4 4 4 0 7TM receptor with intracellular HD hydrolase adh_short PF00106.25 KPI35986.1 - 9.6e-15 54.6 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Aa_trans PF01490.18 KPI35986.1 - 1.8e-14 53.3 27.3 3.1e-14 52.5 27.3 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short_C2 PF13561.6 KPI35986.1 - 1e-11 44.9 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAA_hydrolase PF01557.18 KPI35987.1 - 5.5e-62 209.3 0.0 7.5e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SnoaL_4 PF13577.6 KPI35988.1 - 2.8e-10 40.4 0.0 3.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_2 PF00891.18 KPI35989.1 - 9.7e-15 54.4 0.2 4.5e-14 52.2 0.1 1.9 1 1 1 2 2 2 1 O-methyltransferase domain Herpes_DNAp_acc PF04929.12 KPI35989.1 - 1.1 8.1 5.6 1.8 7.5 5.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SOG2 PF10428.9 KPI35989.1 - 5.2 6.1 8.9 8.5 5.4 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 KPI35991.1 - 1.1e-27 96.8 0.1 2.4e-27 95.7 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI35991.1 - 3.6e-08 33.4 11.5 6.9e-08 32.5 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPI35992.1 - 1.2e-34 119.8 27.1 1.5e-34 119.5 27.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.15 KPI35992.1 - 0.02 13.5 0.5 0.042 12.5 0.5 1.4 1 0 0 1 1 1 0 Chitin synthase UNC-93 PF05978.16 KPI35992.1 - 0.39 10.4 12.3 0.013 15.3 5.5 2.1 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 RRM_2 PF04059.12 KPI35994.1 - 2.2e-20 72.7 0.0 2.8e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 Las1 PF04031.13 KPI35995.1 - 4.5e-37 127.5 0.0 1.2e-18 67.7 0.0 2.2 2 0 0 2 2 2 2 Las1-like PI3_PI4_kinase PF00454.27 KPI35996.1 - 2.3e-48 165.2 0.0 4.4e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KPI35996.1 - 1.8e-29 102.8 0.0 1.2e-28 100.2 0.0 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KPI35996.1 - 1.4e-10 40.8 0.0 3.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain Mad3_BUB1_I PF08311.12 KPI35996.1 - 0.026 14.5 0.3 0.13 12.3 0.3 2.2 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Hydant_A_N PF05378.13 KPI35996.1 - 0.27 10.9 2.1 1.7 8.3 0.0 3.1 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase N-terminal region GMC_oxred_N PF00732.19 KPI35997.1 - 5.1e-56 190.2 0.0 8.7e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI35997.1 - 6.3e-37 127.3 0.2 1.3e-36 126.3 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KPI35997.1 - 3.3e-05 23.3 0.0 0.00099 18.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI35997.1 - 7.7e-05 22.8 0.3 0.00022 21.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPI35997.1 - 9.9e-05 21.6 0.1 0.016 14.3 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KPI35997.1 - 0.00022 20.4 0.6 0.00039 19.6 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KPI35997.1 - 0.00086 19.0 0.3 0.023 14.3 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI35997.1 - 0.0026 16.9 0.3 0.012 14.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI35997.1 - 0.0078 15.0 0.2 0.017 13.8 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KPI35997.1 - 0.014 14.7 0.2 0.062 12.5 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Dynamin_N PF00350.23 KPI35999.1 - 2.4e-44 151.3 0.0 4.7e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPI35999.1 - 5.6e-18 65.2 0.0 4.9e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KPI35999.1 - 9.7e-06 25.6 0.2 0.0002 21.4 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KPI35999.1 - 0.015 15.7 2.2 0.16 12.3 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KPI35999.1 - 0.051 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KPI35999.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SRI PF08236.11 KPI35999.1 - 0.19 11.9 0.5 0.5 10.6 0.5 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain p450 PF00067.22 KPI36000.1 - 3e-61 207.6 0.0 4.4e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KPI36001.1 - 3.1e-13 49.8 0.2 7.9e-13 48.5 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI36001.1 - 0.061 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain TAP42 PF04177.12 KPI36002.1 - 4.7e-76 256.0 0.6 5.8e-76 255.7 0.6 1.0 1 0 0 1 1 1 1 TAP42-like family AnmK PF03702.14 KPI36003.1 - 1.1e-81 274.8 0.0 5e-81 272.6 0.0 1.8 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 KPI36003.1 - 0.053 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FKBP_N_2 PF18023.1 KPI36003.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Ribosomal_L23 PF00276.20 KPI36004.1 - 1.1e-10 41.7 0.1 2.5e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 NACHT PF05729.12 KPI36006.1 - 6e-11 42.5 0.2 8.7e-09 35.5 0.0 3.3 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPI36006.1 - 1.1e-05 25.9 0.2 6.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SBDS_C PF09377.10 KPI36006.1 - 0.0018 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain AAA PF00004.29 KPI36006.1 - 0.0071 16.8 0.0 0.3 11.5 0.0 3.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI36006.1 - 0.0096 16.2 0.1 0.075 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain ThiD2 PF17792.1 KPI36006.1 - 0.043 14.3 0.6 0.098 13.1 0.6 1.6 1 0 0 1 1 1 0 ThiD2 family ATPase_2 PF01637.18 KPI36006.1 - 0.28 11.0 0.6 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_10 PF12846.7 KPI36006.1 - 0.29 10.0 2.1 1.1 8.1 0.5 2.1 2 0 0 2 2 2 0 AAA-like domain ADH_N PF08240.12 KPI36007.1 - 9.6e-30 102.7 1.6 1.7e-29 101.9 1.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI36007.1 - 8.6e-17 61.3 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI36007.1 - 2.2e-10 40.4 0.1 4e-10 39.5 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPI36007.1 - 1.3e-07 31.2 0.2 2.6e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KPI36007.1 - 9.4e-05 23.5 0.0 0.00019 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KPI36007.1 - 0.026 14.8 0.2 0.045 14.0 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain PrmA PF06325.13 KPI36007.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) OB_NTP_bind PF07717.16 KPI36008.1 - 6.7e-22 77.7 0.0 2.4e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KPI36008.1 - 7.3e-19 68.1 0.0 1.8e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPI36008.1 - 8.6e-11 42.2 0.0 2.1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI36008.1 - 3.6e-06 26.9 0.0 8.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPI36008.1 - 0.00062 20.0 0.2 0.0027 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KPI36008.1 - 0.0025 17.5 0.0 0.0096 15.6 0.0 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KPI36008.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 KPI36008.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI36008.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KPI36008.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KPI36008.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KPI36008.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein COMPASS-Shg1 PF05205.12 KPI36009.1 - 2.9e-24 85.7 0.1 2.9e-24 85.7 0.1 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Nup192 PF11894.8 KPI36010.1 - 2.4e-275 916.8 13.1 1.8e-272 907.2 13.1 2.0 1 1 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 GDA1_CD39 PF01150.17 KPI36012.1 - 6.7e-109 364.4 0.0 8.5e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MFS_1 PF07690.16 KPI36013.1 - 1.6e-32 112.8 25.1 1.6e-32 112.8 25.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPI36013.1 - 0.34 10.7 3.9 0.3 10.9 0.1 2.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAD_binding_3 PF01494.19 KPI36014.1 - 1.1e-21 77.4 0.0 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI36014.1 - 1.7e-07 31.2 12.8 9.4e-05 22.1 0.1 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI36014.1 - 1.8e-06 28.0 1.5 6.6e-06 26.3 1.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI36014.1 - 6.2e-05 22.4 2.2 0.0032 16.7 2.4 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI36014.1 - 0.00049 20.6 3.5 0.027 15.0 2.9 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI36014.1 - 0.00082 18.6 7.5 0.002 17.3 7.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KPI36014.1 - 0.0019 17.6 8.5 0.0034 16.8 8.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KPI36014.1 - 0.005 15.9 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.6 KPI36014.1 - 0.0054 16.0 0.5 0.0093 15.3 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI36014.1 - 0.007 15.1 2.6 0.013 14.3 2.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KPI36014.1 - 0.015 14.2 4.0 0.084 11.7 2.8 2.5 2 1 1 3 3 3 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KPI36014.1 - 0.016 14.5 2.9 0.035 13.4 2.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KPI36014.1 - 0.02 14.0 6.5 0.032 13.3 6.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KPI36014.1 - 0.021 14.1 4.4 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPI36014.1 - 0.045 13.0 0.2 2.6 7.2 0.3 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KPI36014.1 - 0.42 9.6 2.2 4.7 6.1 2.2 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.9 KPI36014.1 - 1.2 9.0 3.8 0.6 10.0 0.7 2.1 3 0 0 3 3 3 0 Rossmann-like domain Pro_isomerase PF00160.21 KPI36015.1 - 9.9e-49 165.6 0.1 1.7e-48 164.9 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 KPI36015.1 - 2.4e-05 24.4 0.0 6.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KPI36015.1 - 0.00011 22.4 0.0 0.00055 20.0 0.0 2.3 2 1 0 2 2 2 1 U-box domain Rtf2 PF04641.12 KPI36015.1 - 0.0013 18.2 3.2 0.0021 17.5 0.8 2.5 2 1 0 2 2 2 1 Rtf2 RING-finger GrpB PF04229.14 KPI36017.1 - 1.3e-19 70.9 0.2 3.1e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 GrpB protein Gpr1_Fun34_YaaH PF01184.19 KPI36018.1 - 2.6e-31 108.9 16.3 3.2e-31 108.6 16.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CENP-B_dimeris PF09026.10 KPI36019.1 - 0.044 14.2 2.9 0.097 13.1 2.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zn_clus PF00172.18 KPI36020.1 - 7.7e-05 22.7 14.1 0.00015 21.8 14.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KPI36021.1 - 6.4e-21 75.1 0.1 7.9e-20 71.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI36021.1 - 6.2e-14 53.1 0.3 7.3e-14 52.9 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI36021.1 - 2.1e-06 27.2 0.0 3.7e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI36022.1 - 9.3e-26 91.0 0.0 1.3e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI36022.1 - 1.1e-13 52.3 0.1 1.2e-13 52.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI36022.1 - 0.00039 19.8 0.1 0.00057 19.2 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPI36022.1 - 0.033 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.20 KPI36022.1 - 0.059 13.5 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Sugar_tr PF00083.24 KPI36023.1 - 1.4e-50 172.5 16.0 5.4e-50 170.6 16.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36023.1 - 1e-09 37.8 35.4 1.6e-05 24.0 10.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.8 KPI36023.1 - 9.9 6.1 15.5 2.1 8.3 0.5 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) DnaJ PF00226.31 KPI36024.1 - 1.9e-19 69.5 0.2 4.6e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain BORCS6 PF10157.9 KPI36024.1 - 0.00017 21.8 0.5 0.00026 21.2 0.5 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Apolipoprotein PF01442.18 KPI36024.1 - 0.00032 20.6 8.6 0.00053 19.9 8.6 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.6 KPI36024.1 - 0.00067 19.9 4.1 0.0016 18.7 4.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) Prominin PF05478.11 KPI36024.1 - 0.0021 16.1 3.8 0.0022 16.1 3.8 1.1 1 0 0 1 1 1 1 Prominin DUF1664 PF07889.12 KPI36024.1 - 0.0023 17.9 6.8 0.0038 17.3 5.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) ArsR PF09824.9 KPI36024.1 - 0.0031 17.1 1.6 0.0077 15.8 0.6 1.9 1 1 1 2 2 2 1 ArsR transcriptional regulator IFT57 PF10498.9 KPI36024.1 - 0.0034 16.4 7.2 0.0047 16.0 7.2 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 KPI36024.1 - 0.01 14.7 9.5 0.014 14.3 9.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Terminase_1 PF03354.15 KPI36024.1 - 0.011 14.4 1.3 0.014 14.0 1.3 1.1 1 0 0 1 1 1 0 Phage Terminase DUF4268 PF14088.6 KPI36024.1 - 0.011 15.6 3.0 0.016 15.1 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Vps54_N PF10475.9 KPI36024.1 - 0.019 14.3 8.3 0.25 10.6 4.0 2.3 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex KxDL PF10241.9 KPI36024.1 - 0.027 14.7 9.2 0.047 14.0 5.3 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein FUSC PF04632.12 KPI36024.1 - 0.029 12.9 0.6 0.038 12.5 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lant_dehydr_C PF14028.6 KPI36024.1 - 0.033 13.7 1.8 0.036 13.6 1.8 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term HD_4 PF13328.6 KPI36024.1 - 0.035 13.8 0.8 0.05 13.3 0.8 1.4 1 0 0 1 1 1 0 HD domain DUF2756 PF10956.8 KPI36024.1 - 0.037 14.5 0.6 0.061 13.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Sec8_exocyst PF04048.14 KPI36024.1 - 0.04 13.8 5.2 0.081 12.8 5.2 1.7 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain PRAI PF00697.22 KPI36024.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase NPV_P10 PF05531.12 KPI36024.1 - 0.064 13.7 6.7 1.2 9.6 2.6 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 KPI36024.1 - 0.074 12.8 9.7 0.33 10.8 9.7 2.1 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Med30 PF11315.8 KPI36024.1 - 0.076 13.2 8.0 0.069 13.4 1.4 2.3 1 1 1 2 2 2 0 Mediator complex subunit 30 COG2 PF06148.11 KPI36024.1 - 0.085 12.9 3.7 0.41 10.7 3.7 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 KPI36024.1 - 0.09 13.3 9.5 0.064 13.7 7.7 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 AAA_13 PF13166.6 KPI36024.1 - 0.11 11.2 9.8 0.12 10.9 9.8 1.1 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 KPI36024.1 - 0.14 12.8 3.4 0.36 11.4 3.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HRDC PF00570.23 KPI36024.1 - 0.14 12.2 1.1 0.41 10.7 1.1 1.9 1 1 0 1 1 1 0 HRDC domain Baculo_PEP_C PF04513.12 KPI36024.1 - 0.17 12.0 7.0 0.6 10.1 7.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 KPI36024.1 - 0.17 11.4 5.8 0.62 9.6 6.0 1.8 1 1 1 2 2 2 0 fzo-like conserved region Mce4_CUP1 PF11887.8 KPI36024.1 - 0.17 11.3 2.5 0.23 10.9 2.5 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Colicin PF01024.19 KPI36024.1 - 0.17 11.7 2.4 0.74 9.7 2.4 2.0 1 1 0 1 1 1 0 Colicin pore forming domain Tn7_Tnp_TnsA_C PF08721.11 KPI36024.1 - 0.18 12.4 6.0 0.63 10.7 0.8 3.0 1 1 1 3 3 3 0 TnsA endonuclease C terminal DUF4460 PF14687.6 KPI36024.1 - 0.18 11.8 6.2 0.84 9.7 6.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4460) Phasin_2 PF09361.10 KPI36024.1 - 0.19 12.0 7.5 0.36 11.1 6.8 1.8 1 1 0 1 1 1 0 Phasin protein MscS_porin PF12795.7 KPI36024.1 - 0.23 11.0 15.5 0.13 11.8 13.0 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 KPI36024.1 - 0.24 11.4 11.9 0.14 12.2 6.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Med9 PF07544.13 KPI36024.1 - 0.29 11.3 4.0 0.45 10.6 3.2 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HHH_9 PF17674.1 KPI36024.1 - 0.29 12.1 7.1 0.68 10.9 3.3 3.0 1 1 2 3 3 2 0 HHH domain Sec20 PF03908.13 KPI36024.1 - 0.29 11.1 6.1 0.19 11.6 1.9 2.4 1 1 1 2 2 2 0 Sec20 PIN_8 PF18476.1 KPI36024.1 - 0.34 10.7 6.8 0.34 10.7 5.7 1.6 1 1 0 1 1 1 0 PIN like domain Sec34 PF04136.15 KPI36024.1 - 0.37 10.7 7.4 0.25 11.2 4.3 2.0 1 1 1 2 2 2 0 Sec34-like family DUF948 PF06103.11 KPI36024.1 - 0.38 11.0 7.7 4.3 7.7 7.3 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KPI36024.1 - 0.45 10.0 9.1 0.68 9.5 9.2 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit HisKA_3 PF07730.13 KPI36024.1 - 0.46 11.0 3.7 2 9.0 0.9 2.5 1 1 1 2 2 2 0 Histidine kinase ApoO PF09769.9 KPI36024.1 - 0.47 10.4 1.8 1 9.3 0.7 2.0 1 1 1 2 2 2 0 Apolipoprotein O Baculo_p24 PF05073.12 KPI36024.1 - 0.49 10.1 6.4 0.41 10.4 4.6 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein FliH PF02108.16 KPI36024.1 - 0.5 10.4 4.8 1.5 8.9 3.0 2.1 2 0 0 2 2 2 0 Flagellar assembly protein FliH Rab_bind PF16704.5 KPI36024.1 - 0.5 10.4 4.8 1.4 9.0 1.2 2.3 1 1 1 2 2 2 0 Rab binding domain LUC7 PF03194.15 KPI36024.1 - 0.63 9.7 7.0 0.26 10.9 4.7 1.5 1 1 0 1 1 1 0 LUC7 N_terminus Occludin_ELL PF07303.13 KPI36024.1 - 0.65 10.8 8.0 0.68 10.7 3.5 2.2 1 1 1 2 2 2 0 Occludin homology domain TMPIT PF07851.13 KPI36024.1 - 0.78 8.9 7.1 0.82 8.9 6.5 1.3 1 1 0 1 1 1 0 TMPIT-like protein Spectrin PF00435.21 KPI36024.1 - 0.83 10.2 9.6 0.51 10.8 5.7 2.1 1 1 0 2 2 2 0 Spectrin repeat Cauli_AT PF03233.13 KPI36024.1 - 0.84 9.5 5.3 0.64 9.9 3.5 1.8 1 1 1 2 2 2 0 Aphid transmission protein ECH_2 PF16113.5 KPI36024.1 - 1.1 8.7 9.0 1.5 8.2 7.3 1.7 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF4446 PF14584.6 KPI36024.1 - 1.2 9.1 8.6 3.4 7.6 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Syntaxin-6_N PF09177.11 KPI36024.1 - 1.5 9.5 9.5 7 7.3 6.4 2.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal YtxH PF12732.7 KPI36024.1 - 1.6 9.3 6.7 63 4.2 6.7 2.8 1 1 0 1 1 1 0 YtxH-like protein DUF3810 PF12725.7 KPI36024.1 - 2.2 7.5 7.8 0.69 9.2 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Nre_C PF04895.12 KPI36024.1 - 2.8 7.9 4.8 2.5 8.1 1.1 2.4 1 1 1 2 2 2 0 Archaeal Nre, C-terminal BLOC1_2 PF10046.9 KPI36024.1 - 3.5 8.0 12.8 1.4 9.3 5.4 2.6 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 KPI36024.1 - 3.9 7.4 8.1 13 5.7 0.6 3.5 1 1 2 3 3 3 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 KPI36024.1 - 4.2 7.6 10.2 2.4 8.3 7.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GPO PF05929.11 KPI36024.1 - 4.9 6.7 11.9 9.2 5.8 11.9 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_1 PF00515.28 KPI36025.1 - 4.2e-05 23.2 4.2 0.0068 16.2 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI36025.1 - 0.0009 19.2 4.7 0.15 12.2 0.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPI36025.1 - 0.0024 18.1 7.1 0.025 14.9 2.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI36025.1 - 0.0038 17.1 0.3 1 9.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPI36025.1 - 0.012 16.1 1.3 0.025 15.1 1.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat YukC PF10140.9 KPI36025.1 - 0.025 13.4 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ANAPC3 PF12895.7 KPI36025.1 - 0.06 13.6 0.5 0.16 12.2 0.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 GATase_4 PF13230.6 KPI36026.1 - 1.1e-14 54.0 0.0 9.5e-13 47.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KPI36026.1 - 8.6e-09 35.7 0.0 2e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Fungal_trans PF04082.18 KPI36027.1 - 1.6e-10 40.5 1.3 2.3e-10 40.0 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.14 KPI36028.1 - 7.6e-21 73.7 21.9 4.1e-12 45.7 4.3 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KPI36028.1 - 0.03 15.1 2.5 0.03 15.1 2.5 1.9 2 0 0 2 2 2 0 ER lumen protein retaining receptor DUF5400 PF17379.2 KPI36028.1 - 0.2 12.1 6.0 0.08 13.4 3.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5400) SLATT_fungal PF18142.1 KPI36028.1 - 6 6.9 5.8 12 5.9 5.8 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain CAMSAP_CKK PF08683.11 KPI36029.1 - 0.063 13.4 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated rhaM PF05336.13 KPI36030.1 - 4.3e-33 113.6 0.0 5.3e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase Crystall PF00030.19 KPI36030.1 - 0.05 13.8 0.2 0.13 12.5 0.1 1.9 2 1 0 2 2 2 0 Beta/Gamma crystallin Lon_C PF05362.13 KPI36031.1 - 1.6e-68 230.3 0.3 4.6e-68 228.8 0.4 1.7 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KPI36031.1 - 4.5e-28 98.6 0.0 9.9e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KPI36031.1 - 7.8e-16 58.7 0.0 5e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KPI36031.1 - 7.3e-07 29.1 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KPI36031.1 - 2.4e-06 27.6 0.0 6.1e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI36031.1 - 3.2e-06 27.6 0.0 3.1e-05 24.4 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KPI36031.1 - 2.6e-05 24.0 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KPI36031.1 - 0.00042 19.6 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KPI36031.1 - 0.00043 20.6 0.1 0.01 16.1 0.0 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KPI36031.1 - 0.00048 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KPI36031.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Birna_VP4 PF01768.16 KPI36031.1 - 0.0027 17.6 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_2 PF07724.14 KPI36031.1 - 0.01 16.0 0.0 0.034 14.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KPI36031.1 - 0.019 14.9 0.0 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KPI36031.1 - 0.03 13.9 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPI36031.1 - 0.037 14.2 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPI36031.1 - 0.043 14.4 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI36031.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPI36031.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KPI36031.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KPI36031.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KPI36031.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPI36031.1 - 0.11 13.0 0.9 0.56 10.7 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_PrkA PF08298.11 KPI36031.1 - 0.12 11.3 0.1 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain NB-ARC PF00931.22 KPI36031.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KPI36031.1 - 0.13 11.6 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KPI36031.1 - 0.14 12.1 0.0 0.46 10.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KPI36031.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.0 2 1 0 2 2 1 0 AAA domain PhoH PF02562.16 KPI36031.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-RING_2 PF13639.6 KPI36032.1 - 1.3e-07 31.8 7.6 2.7e-07 30.8 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI36032.1 - 6.3e-06 25.9 8.8 1.3e-05 24.9 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI36032.1 - 7.2e-06 25.6 3.3 7.2e-06 25.6 3.3 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI36032.1 - 0.00082 19.2 9.3 0.0017 18.2 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPI36032.1 - 0.0017 18.6 7.2 0.0052 17.0 7.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KPI36032.1 - 0.0037 17.1 5.9 0.014 15.3 5.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI36032.1 - 0.019 14.9 8.6 0.019 14.9 8.6 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KPI36032.1 - 0.021 14.9 1.4 0.036 14.1 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KPI36032.1 - 0.043 13.6 8.2 0.11 12.3 8.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.6 KPI36032.1 - 0.051 14.4 3.4 2.2 9.3 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_UBOX PF13445.6 KPI36032.1 - 0.072 13.1 6.7 0.17 12.0 6.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Di19 PF05605.12 KPI36032.1 - 0.2 12.0 2.5 3.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KPI36032.1 - 0.46 11.0 2.9 12 6.6 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.6 KPI36032.1 - 2.6 8.0 7.4 55 3.7 7.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 KPI36032.1 - 5.1 7.7 8.0 0.7 10.4 1.8 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING-like PF08746.11 KPI36032.1 - 5.3 7.4 6.9 15 5.9 6.8 1.8 1 1 1 2 2 2 0 RING-like domain MFAP1 PF06991.11 KPI36033.1 - 4.6e-52 177.0 11.4 4.6e-52 177.0 11.4 2.6 3 0 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing NAD_binding_2 PF03446.15 KPI36034.1 - 1e-26 94.0 0.1 1.6e-26 93.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI36034.1 - 8.6e-10 38.9 0.1 1.6e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KPI36034.1 - 0.00029 21.3 0.0 0.0014 19.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sulfotransfer_4 PF17784.1 KPI36035.1 - 1.4e-58 198.3 0.1 1.7e-58 198.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI36035.1 - 0.026 14.9 0.1 0.093 13.1 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family SNF PF00209.18 KPI36036.1 - 1.5e-70 238.4 35.9 4.3e-49 167.6 15.5 2.8 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family Cation_ATPase_C PF00689.21 KPI36036.1 - 0.00042 20.1 0.2 0.00042 20.1 0.2 3.8 3 2 1 4 4 4 1 Cation transporting ATPase, C-terminus DUF3810 PF12725.7 KPI36036.1 - 0.032 13.6 0.4 0.11 11.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Fungal_trans_2 PF11951.8 KPI36037.1 - 3.5e-09 36.0 10.4 7.6e-06 25.0 4.0 3.3 3 1 0 3 3 3 2 Fungal specific transcription factor domain DUF4532 PF15046.6 KPI36037.1 - 0.11 11.7 0.4 0.2 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) COesterase PF00135.28 KPI36038.1 - 2e-62 211.7 0.0 7.5e-62 209.8 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI36038.1 - 1.1e-06 28.7 0.0 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold CAP59_mtransfer PF11735.8 KPI36039.1 - 3.1e-57 194.0 0.0 5.1e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RabGAP-TBC PF00566.18 KPI36040.1 - 3e-33 115.3 0.0 1.1e-32 113.5 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain YjeF_N PF03853.15 KPI36041.1 - 2.6e-33 115.3 0.3 4.1e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KPI36041.1 - 2.9e-06 28.1 0.7 7.6e-06 26.7 0.7 1.7 1 0 0 1 1 1 1 FDF domain zf-RING_2 PF13639.6 KPI36042.1 - 2.2e-08 34.3 4.4 1.6e-07 31.5 0.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KPI36042.1 - 4.2e-08 33.4 2.4 1.4e-07 31.7 0.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KPI36042.1 - 6.7e-07 29.0 5.2 7e-06 25.8 1.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI36042.1 - 1.8e-05 24.6 1.3 3.2e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KPI36042.1 - 2e-05 24.2 3.7 0.0068 16.1 0.3 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KPI36042.1 - 4e-05 23.4 1.9 0.00016 21.4 1.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KPI36042.1 - 0.00013 21.5 0.7 0.00035 20.1 0.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KPI36042.1 - 0.0005 19.9 2.6 0.00072 19.4 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI36042.1 - 0.00091 19.0 0.5 0.00091 19.0 0.5 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KPI36042.1 - 0.0012 18.8 5.1 0.0083 16.1 0.8 3.4 3 1 1 4 4 4 1 RING-type zinc-finger PQ-loop PF04193.14 KPI36042.1 - 0.0017 18.1 0.2 0.0052 16.5 0.2 1.9 1 0 0 1 1 1 1 PQ loop repeat zf-ANAPC11 PF12861.7 KPI36042.1 - 0.0083 16.2 0.4 0.018 15.1 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cadherin_C_2 PF16492.5 KPI36042.1 - 0.1 13.3 0.0 0.3 11.8 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal LCM PF04072.14 KPI36043.1 - 3.6e-20 72.7 0.0 6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.6 KPI36043.1 - 3.9e-18 66.1 0.0 3.6e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Cupin-like domain Kelch_4 PF13418.6 KPI36043.1 - 4.3e-07 29.8 8.9 1.5e-05 24.9 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KPI36043.1 - 0.00042 20.2 0.0 0.1 12.6 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 KPI36043.1 - 0.0081 16.4 2.1 0.24 11.7 0.1 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KPI36043.1 - 0.046 13.7 0.3 25 5.1 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Fungal_trans PF04082.18 KPI36045.1 - 1.1e-14 54.1 0.8 1.7e-14 53.5 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF_assoc_1 PF08355.12 KPI36045.1 - 0.065 12.8 0.4 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 EF hand associated HD_3 PF13023.6 KPI36046.1 - 0.017 15.0 1.2 0.028 14.3 1.2 1.3 1 0 0 1 1 1 0 HD domain PI3K_P85_iSH2 PF16454.5 KPI36046.1 - 0.031 13.9 1.6 0.031 13.9 1.6 2.1 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 KPI36046.1 - 0.032 14.3 13.7 0.39 10.8 2.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 KPI36046.1 - 0.056 11.4 0.2 0.065 11.2 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 KPI36046.1 - 0.14 12.2 14.9 0.56 10.2 14.9 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_C PF15908.5 KPI36046.1 - 0.14 12.4 9.4 1.6 8.9 4.8 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal UPF0242 PF06785.11 KPI36046.1 - 0.15 12.2 16.8 33 4.5 16.8 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med10 PF09748.9 KPI36046.1 - 0.43 10.6 3.4 0.45 10.5 0.2 2.0 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex APG6_N PF17675.1 KPI36046.1 - 0.44 11.1 21.7 0.075 13.6 3.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 KPI36046.1 - 0.48 9.7 11.2 1.1 8.5 11.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KPI36046.1 - 0.56 10.3 3.2 0.8 9.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 KPI36046.1 - 0.58 10.2 17.9 0.16 12.0 4.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 KPI36046.1 - 0.63 10.2 8.2 3.9 7.7 0.2 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Syntaxin_2 PF14523.6 KPI36046.1 - 1.2 9.5 7.0 5.3 7.5 7.0 1.9 1 1 0 1 1 1 0 Syntaxin-like protein Sec34 PF04136.15 KPI36046.1 - 1.6 8.6 6.0 4.2 7.2 0.3 2.1 2 0 0 2 2 2 0 Sec34-like family DUF4201 PF13870.6 KPI36046.1 - 1.7 8.4 13.6 2.1 8.0 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4061 PF13270.6 KPI36046.1 - 1.7 9.0 10.6 0.3 11.4 1.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) Mt_ATP-synt_B PF05405.14 KPI36046.1 - 1.8 8.1 6.3 4.5 6.9 2.4 2.1 1 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Fungal_TACC PF12709.7 KPI36046.1 - 1.9 9.0 6.1 2.2 8.8 2.0 2.4 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIVA PF05103.13 KPI36046.1 - 2.1 8.5 8.4 0.48 10.5 0.8 2.2 2 0 0 2 2 2 0 DivIVA protein Snapin_Pallidin PF14712.6 KPI36046.1 - 3.1 8.3 11.8 2.8 8.4 0.9 2.9 1 1 2 3 3 3 0 Snapin/Pallidin Rootletin PF15035.6 KPI36046.1 - 3.2 7.7 16.3 12 5.8 16.6 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DegS PF05384.11 KPI36046.1 - 9.5 5.7 12.4 11 5.5 2.3 2.2 1 1 1 2 2 2 0 Sensor protein DegS CHRD PF07452.12 KPI36047.1 - 7.2e-14 52.8 0.2 1e-13 52.3 0.2 1.2 1 0 0 1 1 1 1 CHRD domain UCH PF00443.29 KPI36048.1 - 1.1e-28 100.4 0.0 2.4e-28 99.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI36048.1 - 2.8e-06 27.2 0.5 5.8e-06 26.1 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Octopine_DH PF02317.17 KPI36048.1 - 0.026 14.6 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain GFO_IDH_MocA PF01408.22 KPI36049.1 - 1.1e-11 45.5 0.0 5e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_transf_4 PF13439.6 KPI36049.1 - 0.1 12.6 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 MFS_1 PF07690.16 KPI36050.1 - 1e-31 110.2 37.1 1e-31 110.2 37.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily IF4E PF01652.18 KPI36051.1 - 5.5e-24 84.8 0.0 7.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GTP_EFTU PF00009.27 KPI36053.1 - 3.9e-57 192.9 0.2 5.5e-57 192.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KPI36053.1 - 5.4e-19 68.4 1.5 1.4e-18 67.1 1.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KPI36053.1 - 1e-18 67.7 0.0 2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KPI36053.1 - 4.6e-05 23.5 0.0 9.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI36053.1 - 0.00021 21.2 0.0 0.00065 19.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KPI36053.1 - 0.011 15.3 0.4 0.066 12.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KPI36053.1 - 0.012 15.3 0.2 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KPI36053.1 - 0.09 12.1 0.2 0.41 10.0 0.2 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.24 KPI36054.1 - 9.6e-81 271.9 21.0 1.1e-80 271.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36054.1 - 1.2e-27 96.8 31.6 7.5e-24 84.3 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI36054.1 - 0.00019 20.9 6.0 0.00019 20.9 6.0 2.8 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 KPI36054.1 - 0.011 14.0 0.1 0.011 14.0 0.1 1.7 2 0 0 2 2 2 0 BT1 family Rick_17kDa_Anti PF05433.15 KPI36054.1 - 1.8 8.5 10.8 0.066 13.1 3.3 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Hepatitis_core PF00906.20 KPI36055.1 - 1.3 8.5 4.6 2 7.9 4.6 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Cation_efflux PF01545.21 KPI36057.1 - 6e-13 49.0 8.8 8.6e-13 48.5 8.8 1.2 1 0 0 1 1 1 1 Cation efflux family NAD_binding_10 PF13460.6 KPI36058.1 - 3.8e-11 43.2 0.0 6.2e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI36058.1 - 0.00033 20.9 0.0 0.00063 20.0 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI36058.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI36058.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KPI36058.1 - 0.0034 17.8 0.0 0.0067 16.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KPI36058.1 - 0.0055 16.3 0.1 0.0084 15.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KPI36058.1 - 0.013 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 KPI36058.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KPI36058.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IPK PF03770.16 KPI36059.1 - 1.3e-56 191.6 0.0 2.3e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 KPI36059.1 - 0.03 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 zf-RING_2 PF13639.6 KPI36060.1 - 8.4e-10 38.8 4.3 8.4e-10 38.8 4.3 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI36060.1 - 1.2e-06 28.3 4.2 2.8e-06 27.1 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI36060.1 - 3.9e-06 26.6 4.7 1.1e-05 25.2 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI36060.1 - 5.9e-06 26.0 2.5 5.9e-06 26.0 2.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI36060.1 - 2.2e-05 24.1 1.5 4.5e-05 23.1 1.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KPI36060.1 - 0.00028 21.1 6.1 0.0019 18.5 6.1 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KPI36060.1 - 0.001 19.0 3.5 0.0025 17.8 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPI36060.1 - 0.0016 18.4 3.5 0.0016 18.4 3.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KPI36060.1 - 0.0017 17.9 2.3 0.0038 16.8 2.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KPI36060.1 - 0.071 13.2 2.4 0.25 11.4 2.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KPI36060.1 - 0.078 12.8 3.6 0.23 11.3 3.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Mntp PF02659.15 KPI36060.1 - 0.13 12.0 0.4 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 Putative manganese efflux pump zf-H2C2_2 PF13465.6 KPI36060.1 - 1.2 9.7 4.1 2.4 8.8 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI36060.1 - 1.6 9.8 6.3 2.5 9.2 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI36060.1 - 4.1 8.1 5.9 6.3 7.5 0.1 3.5 4 0 0 4 4 3 0 Zinc finger, C2H2 type Beta-lactamase PF00144.24 KPI36061.1 - 1.1e-20 74.1 0.6 7.3e-20 71.5 0.6 2.3 1 1 0 1 1 1 1 Beta-lactamase FAM83 PF07894.12 KPI36061.1 - 3.3 7.2 7.4 0.52 9.8 0.5 2.6 3 0 0 3 3 3 0 FAM83 A-H Jnk-SapK_ap_N PF09744.9 KPI36063.1 - 0.0016 18.6 39.9 0.019 15.2 7.8 3.4 1 1 2 3 3 3 3 JNK_SAPK-associated protein-1 LPG_synthase_TM PF03706.13 KPI36063.1 - 0.017 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Leu_zip PF15294.6 KPI36063.1 - 0.15 11.5 34.5 0.87 9.1 7.6 3.3 1 1 2 3 3 3 0 Leucine zipper YabA PF06156.13 KPI36063.1 - 0.17 12.5 30.1 0.2 12.3 3.7 5.0 1 1 3 4 4 4 0 Initiation control protein YabA FlaC_arch PF05377.11 KPI36063.1 - 0.21 12.0 5.1 12 6.4 0.2 4.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Asp1 PF16993.5 KPI36063.1 - 1.4 8.1 7.7 3.6 6.7 1.2 2.3 1 1 1 2 2 2 0 Accessory Sec system protein Asp1 DUF1664 PF07889.12 KPI36063.1 - 3.1 7.9 22.2 1 9.4 3.9 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF648 PF04890.13 KPI36063.1 - 3.6 7.3 11.1 0.1 12.4 2.8 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF648) ADIP PF11559.8 KPI36063.1 - 4.5 7.4 45.2 4.7 7.3 7.3 4.6 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Fapy_DNA_glyco PF01149.24 KPI36064.1 - 2.3e-25 89.5 0.1 1.1e-24 87.2 0.0 2.1 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KPI36064.1 - 2.5e-16 59.4 0.0 6e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FAD_binding_4 PF01565.23 KPI36065.1 - 4.3e-19 68.6 0.0 6.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0128 PF03673.13 KPI36065.1 - 0.007 15.9 0.2 0.14 11.6 0.4 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0128) HAD_2 PF13419.6 KPI36066.1 - 5.8e-15 55.8 0.0 8.6e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI36066.1 - 2.1e-07 31.4 0.0 2.7e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI36066.1 - 0.00053 20.0 0.0 0.0029 17.7 0.0 2.2 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KPI36066.1 - 0.044 13.9 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.17 KPI36067.1 - 2.6e-10 40.4 0.0 3.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 SnoaL_4 PF13577.6 KPI36068.1 - 0.17 12.1 0.7 0.71 10.0 0.7 2.0 1 1 0 1 1 1 0 SnoaL-like domain SNF2_N PF00176.23 KPI36069.1 - 2e-52 178.1 0.1 2.8e-52 177.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI36069.1 - 6.2e-14 52.3 0.0 2.3e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KPI36069.1 - 0.00025 20.9 6.9 0.00046 20.1 6.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI36069.1 - 0.00027 20.9 3.5 0.0006 19.8 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPI36069.1 - 0.0013 18.5 7.6 0.0025 17.6 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI36069.1 - 0.0026 17.5 2.5 0.0057 16.5 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI36069.1 - 0.0032 17.3 5.9 0.0061 16.4 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI36069.1 - 0.012 15.5 6.6 0.022 14.6 6.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ResIII PF04851.15 KPI36069.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 KPI36069.1 - 0.088 13.0 9.0 0.18 12.0 9.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KPI36069.1 - 1.2 9.6 6.5 1.9 8.9 5.7 1.8 1 1 0 1 1 1 0 Ring finger domain ADH_N PF08240.12 KPI36070.1 - 3.1e-28 97.8 0.3 5.5e-28 97.0 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KPI36070.1 - 4.3e-11 42.5 0.5 1.2e-10 41.1 0.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KPI36070.1 - 0.00022 21.2 0.4 0.00058 19.8 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IF3_C PF00707.22 KPI36071.1 - 5.3e-08 32.7 3.2 7.8e-08 32.2 3.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KPI36071.1 - 5.3e-06 26.2 2.1 8.1e-06 25.6 2.1 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF1844 PF08899.11 KPI36071.1 - 0.017 15.4 3.2 8.8 6.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) A1_Propeptide PF07966.12 KPI36071.1 - 0.13 12.2 0.3 0.43 10.5 0.3 2.0 1 0 0 1 1 1 0 A1 Propeptide GFA PF04828.14 KPI36072.1 - 6.1e-11 42.5 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1610 PF07754.11 KPI36072.1 - 0.022 14.7 0.1 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.6 KPI36072.1 - 0.098 12.4 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-LITAF-like PF10601.9 KPI36072.1 - 4.8 7.5 5.5 4.6 7.6 0.1 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain RPN1_RPN2_N PF17781.1 KPI36073.1 - 2.1e-118 395.2 2.8 3.8e-118 394.4 2.8 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KPI36073.1 - 7.4e-28 96.4 0.0 1.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KPI36073.1 - 7.8e-19 67.1 11.4 4.2e-05 23.8 0.1 7.7 6 1 0 6 6 6 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KPI36073.1 - 4.3e-05 23.8 2.0 1.4 9.3 0.0 4.8 5 1 1 6 6 6 3 HEAT repeats AAA_2 PF07724.14 KPI36073.1 - 0.027 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Cons_hypoth698 PF03601.14 KPI36073.1 - 0.13 11.1 0.1 0.39 9.6 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 698 PQ-loop PF04193.14 KPI36074.1 - 5.1e-36 122.2 11.9 9.3e-18 63.8 2.1 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KPI36074.1 - 7.2 6.7 8.8 0.78 9.8 0.3 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Fungal_trans PF04082.18 KPI36075.1 - 8e-26 90.6 0.8 1.3e-25 90.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPI36075.1 - 2.3e-06 27.8 15.0 0.0017 18.7 2.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI36075.1 - 3.5e-05 24.0 6.3 3.5e-05 24.0 6.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI36075.1 - 0.084 13.8 18.9 0.2 12.6 2.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 KPI36075.1 - 2.4 7.8 4.0 10 5.8 0.1 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain IML1 PF12257.8 KPI36076.1 - 1.7e-110 368.6 0.0 2.4e-110 368.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KPI36076.1 - 1.1e-25 89.4 0.1 2.9e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 KPI36077.1 - 3.8e-17 62.5 0.0 1.2e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 KPI36077.1 - 2.5e-08 34.4 20.9 8.5e-07 29.6 0.2 6.2 8 0 0 8 8 8 2 WD domain, G-beta repeat HEAT PF02985.22 KPI36077.1 - 1.1e-07 31.4 12.4 0.15 12.4 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 KPI36077.1 - 4.1e-05 23.9 1.9 2 8.9 0.0 4.6 3 2 3 6 6 6 4 HEAT repeats ANAPC4_WD40 PF12894.7 KPI36077.1 - 0.022 15.0 0.1 15 6.0 0.0 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 KPI36077.1 - 0.025 15.1 0.2 1.4 9.5 0.1 3.2 3 0 0 3 3 3 0 HEAT-like repeat Kinase-like PF14531.6 KPI36077.1 - 0.053 12.8 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.7 KPI36077.1 - 0.091 12.8 0.1 28 4.7 0.0 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 POT1PC PF16686.5 KPI36080.1 - 3.1e-30 105.1 0.1 9.6e-30 103.5 0.1 1.8 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KPI36080.1 - 8.4e-07 28.9 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 CinA PF02464.17 KPI36080.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Competence-damaged protein TraV PF09676.10 KPI36080.1 - 0.6 11.1 9.0 0.51 11.3 3.9 2.6 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) ATP-synt_B PF00430.18 KPI36080.1 - 2.7 8.1 9.0 5.5 7.1 9.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RVT_1 PF00078.27 KPI36081.1 - 0.059 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF948 PF06103.11 KPI36081.1 - 1.7 9.0 4.4 6.1 7.2 3.4 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sugar_tr PF00083.24 KPI36082.1 - 7e-87 292.1 21.9 8.2e-87 291.9 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36082.1 - 1.9e-26 92.9 60.5 2.6e-23 82.6 29.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI36082.1 - 6e-05 21.7 1.7 6e-05 21.7 1.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KPI36082.1 - 0.011 14.3 22.8 0.15 10.6 5.2 2.9 2 1 0 2 2 2 0 MFS/sugar transport protein OATP PF03137.20 KPI36082.1 - 0.012 13.9 0.1 0.012 13.9 0.1 3.4 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family zf-RNPHF PF08080.12 KPI36082.1 - 0.98 9.4 3.7 14 5.8 1.8 2.5 2 0 0 2 2 2 0 RNPHF zinc finger BT1 PF03092.16 KPI36082.1 - 2.3 6.3 8.0 0.23 9.6 1.6 2.2 2 1 0 2 2 2 0 BT1 family Phosphonate-bd PF12974.7 KPI36083.1 - 1.2e-18 67.6 0.2 2.4e-18 66.6 0.2 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KPI36083.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF3328 PF11807.8 KPI36084.1 - 1.7e-20 73.8 0.9 6.1e-20 72.0 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) FNIP_N PF14636.6 KPI36085.1 - 1.5e-10 42.3 1.2 1.5e-10 42.3 1.2 5.6 4 2 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 KPI36085.1 - 0.0039 17.2 0.2 0.0091 16.0 0.1 1.6 1 1 0 1 1 1 1 Folliculin-interacting protein middle domain Peptidase_C97 PF05903.14 KPI36086.1 - 6.3e-38 130.0 0.0 1.4e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KPI36086.1 - 4.7e-22 78.5 4.0 5e-21 75.1 4.1 2.0 1 1 0 1 1 1 1 PUL domain RA PF00788.23 KPI36086.1 - 0.0048 17.5 0.0 0.0095 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Thioredoxin PF00085.20 KPI36086.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Epimerase PF01370.21 KPI36088.1 - 2.9e-15 56.4 0.0 5.5e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI36088.1 - 1.9e-09 37.7 0.3 8e-09 35.6 0.3 2.0 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPI36088.1 - 1.9e-09 37.0 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPI36088.1 - 3.1e-05 23.5 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPI36088.1 - 0.00028 20.5 0.3 0.00047 19.8 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KPI36088.1 - 0.00034 20.1 0.0 0.049 13.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KPI36088.1 - 0.0018 17.5 0.0 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CFEM PF05730.11 KPI36089.1 - 5.3e-16 58.5 6.8 5.3e-16 58.5 6.8 1.8 2 0 0 2 2 2 1 CFEM domain Fungal_trans PF04082.18 KPI36089.1 - 7.6e-05 21.9 0.2 0.00018 20.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HalOD2 PF18547.1 KPI36089.1 - 0.19 11.7 1.3 0.49 10.4 1.3 1.7 1 0 0 1 1 1 0 Halobacterial output domain 2 Presenilin PF01080.17 KPI36089.1 - 0.53 9.0 4.5 1.2 7.8 4.5 1.5 1 0 0 1 1 1 0 Presenilin Na_H_Exchanger PF00999.21 KPI36090.1 - 5.6e-77 259.1 14.4 6.7e-77 258.8 14.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 KPI36090.1 - 1.4e-76 258.6 43.7 1.9e-76 258.2 43.7 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus YrhC PF14143.6 KPI36090.1 - 0.034 14.2 0.1 0.034 14.2 0.1 2.2 3 0 0 3 3 3 0 YrhC-like protein KAR9 PF08580.10 KPI36090.1 - 0.057 12.0 7.0 0.1 11.1 7.0 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF4190 PF13828.6 KPI36090.1 - 0.09 12.6 0.1 0.09 12.6 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) CRM1_repeat_2 PF18784.1 KPI36090.1 - 0.49 10.1 1.7 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 DUF21 PF01595.20 KPI36090.1 - 0.69 9.6 3.1 1.6 8.4 3.1 1.6 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain TP2 PF01254.18 KPI36090.1 - 0.99 10.0 7.4 3 8.5 2.8 2.9 2 0 0 2 2 2 0 Nuclear transition protein 2 PRP4 PF08799.11 KPI36090.1 - 1.1 8.9 4.1 1.2 8.8 1.0 2.6 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Fungal_trans_2 PF11951.8 KPI36091.1 - 5.4e-09 35.3 0.0 7.6e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KPI36093.1 - 1.7e-75 254.3 0.0 2.5e-75 253.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KPI36093.1 - 3.1e-57 193.7 0.0 6.7e-57 192.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KPI36093.1 - 6.4e-31 107.3 2.3 5.8e-28 97.7 2.3 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36093.1 - 2.1e-23 83.1 2.0 1.9e-12 47.2 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KPI36093.1 - 4.1e-12 46.3 0.0 1.1e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KPI36093.1 - 1.3e-11 44.4 0.1 2.9e-10 40.0 0.0 3.0 4 1 0 4 4 4 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI36093.1 - 5.6e-09 36.2 0.8 0.0001 22.3 0.3 3.2 2 1 1 3 3 3 2 KR domain 3Beta_HSD PF01073.19 KPI36093.1 - 6e-08 32.0 0.0 8.5e-07 28.2 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPI36093.1 - 2.1e-06 27.8 0.3 0.0001 22.3 0.2 3.1 3 0 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPI36093.1 - 4.2e-06 26.1 0.0 1.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPI36093.1 - 0.0056 15.9 2.5 0.65 9.1 0.6 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KPI36093.1 - 0.0074 17.2 1.9 0.02 15.8 0.2 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Arm PF00514.23 KPI36094.1 - 2.2e-92 300.6 14.0 3.6e-13 49.1 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KPI36094.1 - 9.3e-24 83.7 1.8 2.5e-23 82.3 1.8 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KPI36094.1 - 1e-22 79.4 4.1 2.1e-22 78.4 4.1 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KPI36094.1 - 1.4e-21 76.5 5.2 1.7e-08 34.8 0.1 6.1 4 1 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KPI36094.1 - 2.9e-19 69.2 0.1 6.5e-09 36.1 0.0 5.4 1 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 KPI36094.1 - 4.9e-17 60.6 0.3 1.8e-05 24.6 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 KPI36094.1 - 2.6e-07 30.4 0.1 0.013 15.0 0.0 3.7 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KPI36094.1 - 1.9e-05 23.5 0.0 0.00038 19.1 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KPI36094.1 - 0.00016 21.8 0.0 2 8.5 0.0 4.5 3 2 0 4 4 4 1 V-ATPase subunit H Cnd1 PF12717.7 KPI36094.1 - 0.0018 18.3 0.1 3.8 7.5 0.1 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KPI36094.1 - 0.015 15.9 4.9 1 10.2 0.0 4.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Mo25 PF08569.11 KPI36094.1 - 0.074 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Mo25-like RICTOR_V PF14668.6 KPI36094.1 - 0.085 13.1 5.6 3.1 8.1 0.1 4.6 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Beta-lactamase PF00144.24 KPI36095.1 - 1.9e-13 50.4 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Acyltransferase PF01553.21 KPI36097.1 - 1.8e-17 63.2 0.0 4.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DUF3446 PF11928.8 KPI36097.1 - 0.57 10.5 8.2 0.94 9.8 3.9 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain GDA1_CD39 PF01150.17 KPI36098.1 - 3.7e-96 322.4 0.0 4.8e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-RING_2 PF13639.6 KPI36099.1 - 5.9e-06 26.5 9.2 5.9e-06 26.5 9.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI36099.1 - 0.0003 20.6 10.2 0.00052 19.8 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI36099.1 - 0.00049 19.8 4.6 0.001 18.8 4.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI36099.1 - 0.0016 18.3 9.5 0.0027 17.5 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI36099.1 - 0.0065 16.4 10.3 0.013 15.5 10.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KPI36099.1 - 0.012 15.8 8.5 0.037 14.3 8.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KPI36099.1 - 0.049 13.5 7.0 0.12 12.3 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TMEM171 PF15471.6 KPI36099.1 - 0.18 10.8 0.2 0.27 10.2 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-RING_UBOX PF13445.6 KPI36099.1 - 0.4 10.7 7.5 0.78 9.8 7.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KPI36099.1 - 1.6 8.9 6.6 8.9 6.5 6.6 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 KPI36099.1 - 1.6 8.9 8.4 0.15 12.2 2.7 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 KPI36099.1 - 1.8 8.4 13.1 5.9 6.8 8.9 3.0 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain TRAPP PF04051.16 KPI36100.1 - 7.7e-33 113.3 0.0 9.4e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-RING_2 PF13639.6 KPI36101.1 - 4.7e-10 39.7 5.3 7.1e-10 39.1 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI36101.1 - 1.2e-06 28.3 4.6 1.8e-06 27.6 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI36101.1 - 1.5e-06 27.8 1.9 3.1e-06 26.8 1.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI36101.1 - 9e-06 25.5 2.9 1.4e-05 24.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI36101.1 - 6.8e-05 22.8 2.5 0.00012 22.0 2.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPI36101.1 - 0.00011 22.0 3.9 0.00018 21.4 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPI36101.1 - 0.00025 20.8 1.5 0.00051 19.8 1.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KPI36101.1 - 0.003 17.3 1.2 0.0048 16.7 1.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KPI36101.1 - 0.0038 17.5 10.8 0.02 15.2 10.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KPI36101.1 - 0.09 12.4 3.4 0.14 11.8 3.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KPI36101.1 - 0.1 12.4 2.6 0.22 11.4 2.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 HTH_45 PF14947.6 KPI36101.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix zinc_ribbon_16 PF17034.5 KPI36101.1 - 0.17 12.1 4.5 0.14 12.4 2.7 1.7 1 1 0 1 1 1 0 Zinc-ribbon like family Macoilin PF09726.9 KPI36101.1 - 0.17 10.4 6.1 0.22 10.0 6.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 KPI36101.1 - 0.39 10.0 3.8 0.6 9.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 KPI36101.1 - 1.4 9.1 3.9 2 8.7 3.9 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein TRAF_BIRC3_bd PF16673.5 KPI36101.1 - 4.5 7.1 8.7 0.83 9.5 1.2 2.5 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain zf-ANAPC11 PF12861.7 KPI36101.1 - 5.4 7.2 6.4 20 5.3 6.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger bZIP_1 PF00170.21 KPI36102.1 - 5.2e-06 26.5 7.1 7.8e-06 25.9 7.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI36102.1 - 0.43 10.7 12.0 1.2 9.3 12.0 1.7 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KPI36102.1 - 2.1 8.9 11.9 5.2 7.6 11.9 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 KPI36103.1 - 7.4e-30 103.9 0.0 1.2e-27 96.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36103.1 - 9e-18 64.7 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36103.1 - 2e-08 34.4 0.1 3.5e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI36103.1 - 2.2e-06 27.3 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI36103.1 - 0.00019 21.0 0.1 0.00037 20.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 KPI36103.1 - 0.039 13.2 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 KPI36103.1 - 0.12 11.7 0.1 0.27 10.5 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KPI36103.1 - 0.17 11.7 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KPI36103.1 - 0.17 11.1 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family DUF3176 PF11374.8 KPI36104.1 - 6.4e-30 103.5 0.4 2e-29 101.9 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Abhydrolase_3 PF07859.13 KPI36105.1 - 1e-35 123.5 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI36105.1 - 0.00011 21.2 0.1 0.00016 20.7 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family HSP70 PF00012.20 KPI36106.1 - 9e-12 44.0 0.2 1e-10 40.5 0.0 2.8 2 1 0 2 2 2 1 Hsp70 protein SURF6 PF04935.12 KPI36106.1 - 0.064 13.0 6.4 0.12 12.1 6.4 1.4 1 0 0 1 1 1 0 Surfeit locus protein 6 DnaJ PF00226.31 KPI36107.1 - 4.7e-16 58.7 0.3 1.6e-15 57.0 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain NPR1_interact PF15699.5 KPI36107.1 - 0.047 14.3 9.4 0.054 14.1 0.2 3.8 4 0 0 4 4 4 0 NPR1 interacting RPW8 PF05659.11 KPI36108.1 - 0.13 12.0 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MFS_1 PF07690.16 KPI36109.1 - 1.4e-23 83.4 17.8 1.4e-23 83.4 17.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI36109.1 - 1.2e-05 24.0 3.7 2.4e-05 23.0 3.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1918 PF08940.11 KPI36111.1 - 0.18 11.4 0.0 0.51 10.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Notch PF00066.17 KPI36111.1 - 0.26 11.8 2.5 0.65 10.5 2.5 1.6 1 0 0 1 1 1 0 LNR domain Sugar_tr PF00083.24 KPI36112.1 - 1.4e-22 80.2 19.8 7.8e-20 71.1 19.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Ribosomal_S19 PF00203.21 KPI36113.1 - 2.8e-33 113.6 0.1 3.8e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 CagD PF16567.5 KPI36113.1 - 0.15 11.8 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Cpn60_TCP1 PF00118.24 KPI36114.1 - 1.3e-149 499.0 13.1 1.5e-149 498.8 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ADH_zinc_N PF00107.26 KPI36115.1 - 4.9e-24 84.8 0.1 8.3e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI36115.1 - 3.3e-19 68.8 1.3 6.3e-19 67.9 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI36115.1 - 1.9e-12 48.3 0.0 3.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase APG17 PF04108.12 KPI36116.1 - 0.036 13.2 0.5 0.054 12.6 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Glyco_transf_20 PF00982.21 KPI36116.1 - 0.086 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 UCH PF00443.29 KPI36117.1 - 1.3e-57 195.3 0.0 3.2e-57 194.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI36117.1 - 1e-28 100.9 0.3 3.1e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase eIF3_subunit PF08597.10 KPI36117.1 - 0.012 15.5 10.5 0.012 15.5 10.5 2.9 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit Peptidase_C98 PF15499.6 KPI36117.1 - 0.018 14.5 4.8 0.24 10.8 2.3 3.1 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase YSIRK_signal PF04650.17 KPI36117.1 - 0.056 13.3 2.1 0.12 12.3 2.1 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide DUF3530 PF12048.8 KPI36117.1 - 0.75 9.1 16.1 0.051 13.0 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Mito_carr PF00153.27 KPI36118.1 - 2e-53 178.3 0.3 2.6e-19 68.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.8 KPI36118.1 - 0.029 14.7 0.9 0.091 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) DAP_B PF07930.12 KPI36120.1 - 1.3e-51 175.2 0.0 1.9e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 KPI36120.1 - 2.1e-42 145.5 0.1 4.2e-42 144.6 0.1 1.4 2 0 0 2 2 2 1 Beta-lactamase Aminotran_1_2 PF00155.21 KPI36122.1 - 2.3e-15 56.6 0.0 3.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KPI36122.1 - 0.031 13.6 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 KPI36122.1 - 0.035 12.9 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Virulence_fact PF13769.6 KPI36124.1 - 0.0017 18.5 1.1 0.068 13.4 0.2 2.9 2 0 0 2 2 2 1 Virulence factor Mto2_bdg PF12808.7 KPI36124.1 - 0.11 12.8 3.2 2 8.8 0.1 3.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region UPF0242 PF06785.11 KPI36124.1 - 0.46 10.6 5.0 1.1 9.4 5.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_tran_WecB PF03808.13 KPI36125.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF485 PF04341.12 KPI36125.1 - 2.8 8.0 6.3 1 9.4 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Metallophos PF00149.28 KPI36126.1 - 2.9e-06 27.9 0.2 4.9e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CcmD PF04995.14 KPI36126.1 - 0.12 12.5 1.0 0.55 10.4 1.0 2.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ADH_zinc_N PF00107.26 KPI36127.1 - 7.3e-25 87.5 0.0 1.3e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI36127.1 - 1.4e-22 81.2 0.0 2.8e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI36127.1 - 1.5e-06 28.0 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KPI36127.1 - 0.05 13.0 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AMP-binding PF00501.28 KPI36129.1 - 4.9e-206 684.3 0.1 1.3e-71 241.4 0.1 4.2 3 1 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KPI36129.1 - 5.4e-114 381.4 0.1 1.3e-35 123.0 0.0 6.8 6 1 0 6 6 6 5 Condensation domain PP-binding PF00550.25 KPI36129.1 - 5.6e-33 113.1 0.5 9.5e-09 35.5 0.0 5.2 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPI36129.1 - 2.6e-11 44.3 0.0 0.012 16.5 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KPI36132.1 - 6.3e-32 110.9 27.3 6.3e-32 110.9 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hormone_3 PF00159.18 KPI36132.1 - 4.1 7.6 5.6 12 6.1 0.1 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide Pyrophosphatase PF00719.19 KPI36133.1 - 1.6e-58 197.0 0.2 2e-58 196.7 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sugar_tr PF00083.24 KPI36135.1 - 4.8e-105 352.0 24.9 5.5e-105 351.8 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36135.1 - 2e-24 86.2 34.2 2.2e-23 82.8 26.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily EF-hand_6 PF13405.6 KPI36136.1 - 3.4e-14 51.5 1.7 3e-05 23.6 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KPI36136.1 - 1.7e-12 45.9 4.5 8.1e-06 25.0 0.1 4.7 4 1 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KPI36136.1 - 2e-09 37.7 1.3 0.0046 17.4 0.1 3.3 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KPI36136.1 - 6.6e-07 28.5 6.6 0.00044 19.6 0.2 3.2 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KPI36136.1 - 5.6e-06 26.1 1.1 0.0066 16.3 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair Sec20 PF03908.13 KPI36137.1 - 7.9e-16 57.8 0.5 1.7e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Sec20 BEX PF04538.12 KPI36137.1 - 0.1 13.2 0.4 0.1 13.2 0.4 3.2 2 1 1 3 3 3 0 Brain expressed X-linked like family TCRP1 PF14944.6 KPI36137.1 - 0.52 10.2 1.7 1 9.3 1.7 1.4 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 Syntaxin-6_N PF09177.11 KPI36137.1 - 1.2 9.7 5.7 6.8 7.3 1.5 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CrgA PF06781.12 KPI36137.1 - 1.3 9.2 8.0 0.25 11.4 3.7 2.1 2 0 0 2 2 2 0 Cell division protein CrgA DUF4407 PF14362.6 KPI36137.1 - 3.9 6.7 16.5 9.8 5.4 16.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MA3 PF02847.17 KPI36138.1 - 1.7e-27 95.6 0.1 6.9e-27 93.7 0.0 2.1 2 0 0 2 2 2 1 MA3 domain ORC6 PF05460.13 KPI36138.1 - 3.4 6.8 7.2 0.32 10.2 2.6 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pyr_redox_2 PF07992.14 KPI36139.1 - 2.7e-07 30.1 0.0 4.7e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI36139.1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI36139.1 - 0.0081 16.2 0.0 0.067 13.2 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thioredoxin_4 PF13462.6 KPI36141.1 - 8.8e-10 39.0 0.0 1.1e-08 35.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin Alpha-amylase PF00128.24 KPI36142.1 - 3.4e-57 194.5 0.1 1e-56 192.9 0.1 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KPI36142.1 - 9e-05 20.9 0.0 0.00088 17.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 GHL10 PF02638.15 KPI36142.1 - 0.013 14.6 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 hDGE_amylase PF14701.6 KPI36142.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain adh_short PF00106.25 KPI36143.1 - 1.5e-29 102.9 0.0 1.9e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36143.1 - 6.5e-14 52.1 0.1 7.8e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36143.1 - 1.4e-05 25.1 0.1 2.1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KPI36143.1 - 0.017 14.3 0.2 0.066 12.3 0.1 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPI36143.1 - 0.037 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KPI36143.1 - 0.044 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_12 PF01670.16 KPI36144.1 - 2.9e-17 63.4 4.9 4.4e-16 59.5 4.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Peptidase_S10 PF00450.22 KPI36145.1 - 3.1e-80 270.6 6.8 5.4e-80 269.8 6.8 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase UDPG_MGDP_dh_C PF03720.15 KPI36145.1 - 0.092 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ChaC PF04752.12 KPI36146.1 - 1.1e-53 181.9 0.0 1.4e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Cation_efflux PF01545.21 KPI36147.1 - 2.6e-52 177.5 10.3 3.8e-51 173.7 10.3 2.0 1 1 0 1 1 1 1 Cation efflux family Eno-Rase_NADH_b PF12242.8 KPI36147.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DnaA_N PF11638.8 KPI36148.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaA N-terminal domain CPSase_L_D2 PF02786.17 KPI36149.1 - 9e-111 368.4 0.0 5.3e-84 280.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KPI36149.1 - 1.6e-39 135.0 0.1 5.6e-39 133.2 0.1 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KPI36149.1 - 1.6e-21 76.7 0.0 5e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KPI36149.1 - 9.5e-20 71.0 0.2 4.6e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KPI36149.1 - 1e-13 51.1 0.0 8.1e-07 28.9 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KPI36149.1 - 4.3e-07 30.1 0.1 0.0019 18.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KPI36149.1 - 1.9e-05 24.5 0.1 0.017 14.9 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KPI36149.1 - 2.2e-05 24.0 0.2 0.026 14.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KPI36149.1 - 0.00022 20.9 0.1 0.00083 19.0 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KPI36149.1 - 0.00031 20.4 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Pkinase PF00069.25 KPI36151.1 - 4.7e-56 190.1 0.0 6.5e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36151.1 - 6.2e-40 137.1 0.0 1e-39 136.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI36151.1 - 3.4e-05 22.8 0.0 7.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KPI36151.1 - 0.00018 20.9 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KPI36151.1 - 0.00023 21.2 1.7 0.0086 16.0 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KPI36151.1 - 0.0028 17.0 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPI36151.1 - 0.039 13.6 0.2 0.19 11.3 0.2 2.0 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KPI36151.1 - 0.27 10.1 0.2 0.88 8.4 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain ATP_transf PF09830.9 KPI36152.1 - 6.6e-19 67.8 0.1 1.3e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase RCR PF12273.8 KPI36153.1 - 2.2e-22 80.0 5.1 3.2e-22 79.4 5.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red LysE PF01810.18 KPI36153.1 - 0.0085 15.6 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator Rhabdo_glycop PF00974.18 KPI36153.1 - 0.3 9.5 0.4 0.41 9.0 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein MRP_L53 PF10780.9 KPI36155.1 - 2.9e-12 46.5 0.1 4.4e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 TPR_11 PF13414.6 KPI36156.1 - 0.00028 20.5 0.6 0.005 16.5 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 KPI36156.1 - 0.00071 20.0 2.0 6.8 7.3 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI36156.1 - 0.0067 16.7 0.1 1.9 9.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPI36156.1 - 0.039 14.2 6.3 2.6 8.4 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI36156.1 - 0.1 13.4 6.1 9.7 7.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI36156.1 - 0.42 10.5 5.4 3.9 7.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPI36156.1 - 1.4 9.6 6.9 2.5 8.8 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI36156.1 - 6.5 7.1 8.5 13 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC_CDC26 PF10471.9 KPI36157.1 - 1.7e-11 44.8 2.4 3.8e-11 43.7 2.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 CBM_20 PF00686.19 KPI36158.1 - 2.1e-27 94.9 0.1 2.7e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Starch binding domain DUF2456 PF10445.9 KPI36159.1 - 0.031 14.3 0.5 0.052 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) DUF2944 PF11161.8 KPI36159.1 - 0.065 13.1 0.1 0.47 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Cutinase PF01083.22 KPI36161.1 - 5.2e-47 160.1 0.0 6.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPI36161.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 KPI36161.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.11 KPI36161.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) NmrA PF05368.13 KPI36162.1 - 1.4e-34 119.6 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36162.1 - 1.8e-09 37.8 0.2 2.7e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI36162.1 - 8.5e-05 22.1 0.1 0.00017 21.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPI36162.1 - 0.081 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Met_10 PF02475.16 KPI36164.1 - 4.9e-62 209.2 0.0 7e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF5304 PF17230.2 KPI36164.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5304) Condensation PF00668.20 KPI36165.1 - 3.9e-59 200.5 0.0 3.9e-43 147.8 0.0 3.8 2 1 1 3 3 3 3 Condensation domain PP-binding PF00550.25 KPI36165.1 - 4.5e-23 81.4 0.6 2.9e-10 40.4 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site DUF2789 PF10982.8 KPI36165.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) VSP PF03302.13 KPI36168.1 - 0.00043 19.2 1.1 0.00043 19.2 1.1 2.2 2 1 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 KPI36168.1 - 0.0011 19.1 0.5 0.0022 18.1 0.5 1.5 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 KPI36168.1 - 0.048 13.5 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Sporozoite_P67 PF05642.11 KPI36168.1 - 4.6 5.2 11.4 5.7 4.9 11.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CTP_transf_like PF01467.26 KPI36169.1 - 0.00016 21.9 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like RRM_1 PF00076.22 KPI36170.1 - 2e-22 78.8 0.1 3e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI36170.1 - 0.0079 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif HATPase_c PF02518.26 KPI36171.1 - 1.2e-28 99.9 0.1 2.1e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPI36171.1 - 4.3e-20 71.5 0.1 1.4e-19 69.9 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KPI36171.1 - 7.3e-19 68.0 0.3 2.8e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 KPI36171.1 - 5.2e-17 61.9 0.2 4.4e-16 58.9 0.2 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KPI36171.1 - 1.2e-14 54.4 0.0 2.2e-06 27.9 0.0 4.4 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 KPI36171.1 - 2e-12 47.3 0.2 1.8e-05 25.0 0.0 5.3 4 1 0 4 4 4 2 PAS fold PAS PF00989.25 KPI36171.1 - 4.4e-07 29.9 0.0 0.14 12.2 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_10 PF13596.6 KPI36171.1 - 0.0047 17.5 0.0 1.6 9.4 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KPI36171.1 - 0.021 14.8 0.0 0.21 11.6 0.0 2.7 3 0 0 3 3 3 0 PAS domain HATPase_c_3 PF13589.6 KPI36171.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tim17 PF02466.19 KPI36173.1 - 4.4e-13 49.6 1.0 8.5e-13 48.7 1.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sulfotransfer_4 PF17784.1 KPI36174.1 - 7.5e-59 199.1 0.1 3.7e-58 196.9 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI36174.1 - 0.0013 19.1 0.3 0.0088 16.4 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Methyltransf_28 PF02636.17 KPI36174.1 - 0.06 13.0 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FAD_binding_2 PF00890.24 KPI36175.1 - 9.5e-112 374.1 7.3 1.1e-92 311.3 1.4 2.1 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.20 KPI36175.1 - 1e-44 151.6 0.2 1.5e-44 151.0 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KPI36175.1 - 1.1e-05 24.8 0.1 0.0037 16.5 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI36175.1 - 7.5e-05 22.0 1.0 0.25 10.4 1.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KPI36175.1 - 0.00061 19.1 0.2 0.14 11.4 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KPI36175.1 - 0.0036 16.6 0.4 0.011 15.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 KPI36176.1 - 2.3e-109 365.7 0.0 2.8e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI36176.1 - 6.8e-09 35.4 1.5 2.2e-05 23.8 0.1 3.4 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI36176.1 - 0.00039 19.7 0.1 0.27 10.4 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KPI36177.1 - 9.4e-66 218.4 11.8 2.6e-12 47.2 0.0 7.8 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI36177.1 - 7e-61 201.9 22.4 5.5e-10 39.6 0.1 10.2 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI36177.1 - 8e-50 166.3 13.3 6.2e-08 32.8 0.1 10.2 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI36177.1 - 8.4e-49 157.9 2.4 0.0011 19.3 0.1 14.3 14 0 0 14 14 14 11 Ankyrin repeat Ank PF00023.30 KPI36177.1 - 1.7e-40 135.7 16.2 0.00042 20.6 0.5 14.4 13 1 1 14 14 14 9 Ankyrin repeat NACHT PF05729.12 KPI36177.1 - 1.1e-11 44.9 0.0 2.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 KPI36177.1 - 4.1e-11 42.6 0.7 1.1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KPI36177.1 - 6.1e-05 23.3 0.0 0.00022 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI36177.1 - 0.00071 20.0 0.0 0.0055 17.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KPI36177.1 - 0.042 13.0 0.3 0.21 10.8 0.3 2.0 1 1 0 1 1 1 0 NB-ARC domain GCP_N_terminal PF17681.1 KPI36178.1 - 0.013 15.1 0.5 0.029 14.0 0.5 1.5 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal ApoLp-III PF07464.11 KPI36178.1 - 0.039 14.1 0.3 0.12 12.5 0.1 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PTRF_SDPR PF15237.6 KPI36178.1 - 0.079 12.6 3.1 0.23 11.0 3.1 1.7 1 0 0 1 1 1 0 PTRF/SDPR family Syntaxin-6_N PF09177.11 KPI36178.1 - 0.16 12.5 11.9 0.13 12.8 2.2 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 KPI36178.1 - 0.33 10.8 6.4 0.19 11.5 3.9 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF844 PF05815.11 KPI36178.1 - 0.37 9.9 3.6 0.2 10.8 1.5 1.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) Exonuc_VII_L PF02601.15 KPI36178.1 - 1.3 8.5 12.8 1.1 8.7 5.7 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF812 PF05667.11 KPI36178.1 - 2.5 6.9 11.5 3.3 6.5 10.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) EzrA PF06160.12 KPI36178.1 - 2.5 6.2 7.9 7 4.7 0.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 KPI36178.1 - 6.6 6.9 6.1 2.3 8.4 0.3 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MFS_2 PF13347.6 KPI36179.1 - 1.5e-11 43.5 7.5 1.5e-11 43.5 7.5 2.5 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KPI36179.1 - 0.084 11.7 6.1 0.1 11.4 2.3 2.5 2 1 0 2 2 2 0 MFS_1 like family GCD14 PF08704.10 KPI36180.1 - 2.6e-06 27.3 0.1 0.005 16.5 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Fungal_trans PF04082.18 KPI36183.1 - 3.1e-06 26.4 0.4 5.1e-06 25.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI36184.1 - 4.9e-05 22.4 6.8 4.9e-05 22.4 6.8 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily STT3 PF02516.14 KPI36185.1 - 8.6e-140 466.9 34.9 4.5e-135 451.3 33.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Bac_luciferase PF00296.20 KPI36186.1 - 2.5e-57 194.7 0.2 3.3e-57 194.3 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CLP_protease PF00574.23 KPI36187.1 - 4e-67 225.6 0.0 7.2e-66 221.5 0.0 2.2 1 1 0 1 1 1 1 Clp protease Fungal_trans PF04082.18 KPI36187.1 - 8.3e-13 48.0 0.0 1.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 KPI36188.1 - 0.00066 19.3 0.1 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Cupin domain CKS PF01111.19 KPI36189.1 - 4.4e-32 110.2 0.2 5.7e-32 109.8 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TMF_TATA_bd PF12325.8 KPI36190.1 - 0.018 15.3 1.8 0.035 14.3 1.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding VWA_2 PF13519.6 KPI36191.1 - 8.3e-13 48.9 0.0 1e-05 26.1 0.0 2.9 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 KPI36191.1 - 2.4e-05 24.7 0.2 4.6e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KPI36191.1 - 0.014 15.3 2.3 0.028 14.3 2.3 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Ssl1 PF04056.14 KPI36191.1 - 0.06 13.2 0.1 0.37 10.6 0.1 2.1 3 0 0 3 3 3 0 Ssl1-like Rick_17kDa_Anti PF05433.15 KPI36192.1 - 1.5 8.8 8.3 0.067 13.1 2.0 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain NAD_binding_1 PF00175.21 KPI36193.1 - 6e-08 33.3 0.0 2e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KPI36193.1 - 0.00016 21.8 0.0 0.53 10.4 0.1 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI36193.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain SKG6 PF08693.10 KPI36194.1 - 2.2e-05 23.7 0.5 4.2e-05 22.9 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KPI36194.1 - 0.00036 20.7 0.9 0.00052 20.1 0.9 1.2 1 0 0 1 1 1 1 Podoplanin TPPII_N PF12583.8 KPI36194.1 - 5.8 7.5 11.1 13 6.3 11.1 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Ribosomal_60s PF00428.19 KPI36195.1 - 1.4e-25 89.7 7.6 1.7e-25 89.4 7.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4641 PF15483.6 KPI36195.1 - 0.061 12.4 1.7 0.078 12.1 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) EF-hand_14 PF17959.1 KPI36195.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Mito_carr PF00153.27 KPI36196.1 - 1.6e-59 197.9 0.9 3.9e-21 74.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 KPI36197.1 - 1.2e-24 86.9 0.0 7.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 KPI36197.1 - 3.4e-07 30.6 0.2 1.9e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 Calpain large subunit, domain III Glucodextran_C PF09985.9 KPI36197.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase MIT PF04212.18 KPI36197.1 - 0.031 14.3 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CBFD_NFYB_HMF PF00808.23 KPI36198.1 - 6.9e-21 74.3 1.2 9e-21 73.9 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPI36198.1 - 7.7e-05 23.1 0.1 0.00014 22.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KPI36198.1 - 0.00077 19.4 0.0 0.00098 19.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KPI36198.1 - 0.00085 19.3 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 KPI36198.1 - 0.032 14.7 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-T_C PF15511.6 KPI36198.1 - 0.057 13.5 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold LepB_N PF18640.1 KPI36198.1 - 0.18 11.4 0.2 1.6 8.3 0.0 2.2 2 1 0 2 2 2 0 LepB N-terminal domain Sulfotransfer_4 PF17784.1 KPI36199.1 - 7.5e-69 231.8 0.0 8.9e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI36199.1 - 0.00029 21.3 0.1 0.02 15.3 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Glyco_transf_22 PF03901.17 KPI36200.1 - 1e-35 123.8 19.5 1.3e-35 123.5 19.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Abhydrolase_3 PF07859.13 KPI36201.1 - 2.7e-06 27.4 1.1 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI36201.1 - 3.4e-05 24.6 0.3 4.8e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KPI36201.1 - 0.00065 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KPI36201.1 - 0.0048 16.2 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 KPI36201.1 - 0.039 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LIDHydrolase PF10230.9 KPI36201.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase AA_permease_2 PF13520.6 KPI36202.1 - 7.2e-54 183.2 54.7 8.7e-54 183.0 54.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI36202.1 - 4.3e-25 88.2 46.9 5.9e-25 87.8 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 KPI36202.1 - 0.041 14.0 0.1 0.62 10.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) adh_short PF00106.25 KPI36203.1 - 9.3e-22 77.4 0.0 1.3e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36203.1 - 2.9e-13 49.9 0.1 3.8e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI36203.1 - 0.037 13.5 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI36203.1 - 0.053 12.9 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sybindin PF04099.12 KPI36204.1 - 1.2e-36 125.8 0.0 1.5e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KPI36204.1 - 0.0023 18.1 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Stevor PF17410.2 KPI36205.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Hydrolase_4 PF12146.8 KPI36206.1 - 1.2e-10 41.1 0.0 2.6e-06 26.9 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI36206.1 - 9.9e-06 25.4 0.2 0.0036 17.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI36206.1 - 0.00059 19.4 0.1 0.00075 19.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KPI36206.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Tna_leader PF08053.11 KPI36206.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Tryptophanase operon leader peptide EMG1 PF03587.14 KPI36207.1 - 6.2e-80 267.4 0.0 7.2e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 KPI36207.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 HTH_32 PF13565.6 KPI36208.1 - 0.042 14.5 0.1 0.22 12.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Sdh_cyt PF01127.22 KPI36209.1 - 6.4e-10 39.1 1.2 9.7e-10 38.5 1.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Virul_fac_BrkB PF03631.15 KPI36209.1 - 0.042 13.5 1.0 0.06 12.9 1.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Fungal_trans PF04082.18 KPI36210.1 - 2e-09 36.9 0.0 3.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.24 KPI36211.1 - 7.8e-85 285.8 0.1 5.6e-72 243.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KPI36211.1 - 4.3e-14 52.6 0.1 2.6e-13 50.1 0.1 2.3 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 KPI36211.1 - 2.6e-08 34.0 0.0 6.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI36211.1 - 6.7e-06 25.9 0.0 2.1e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box PF00505.19 KPI36211.1 - 1.3e-05 25.5 0.4 0.0062 16.9 0.3 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box NAD_binding_9 PF13454.6 KPI36211.1 - 0.0002 21.4 0.1 0.045 13.7 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI36211.1 - 0.00044 19.6 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI36211.1 - 0.012 14.7 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HMG_box_2 PF09011.10 KPI36211.1 - 0.017 15.7 0.2 0.08 13.6 0.2 2.1 1 1 0 1 1 1 0 HMG-box domain Pyr_redox PF00070.27 KPI36211.1 - 0.15 12.6 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_25 PF01755.17 KPI36212.1 - 0.0004 20.3 0.2 0.0035 17.2 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) motB PF17613.2 KPI36212.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Modifier of transcription DUF3392 PF11872.8 KPI36212.1 - 0.17 12.2 0.0 0.38 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Cgr1 PF03879.14 KPI36213.1 - 3.1e-32 111.2 30.7 3.5e-32 111.0 30.7 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.12 KPI36213.1 - 0.042 14.2 10.3 0.049 14.0 10.3 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal VIR_N PF15912.5 KPI36213.1 - 0.22 11.1 8.1 0.27 10.8 8.1 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 KPI36213.1 - 2.5 7.9 13.3 2.6 7.8 13.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 COX16 PF14138.6 KPI36213.1 - 3.3 8.3 12.2 5.7 7.5 12.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 SPT2 PF08243.11 KPI36214.1 - 5.7e-10 39.7 10.6 5.7e-10 39.7 10.6 1.8 2 0 0 2 2 2 1 SPT2 chromatin protein Xan_ur_permease PF00860.20 KPI36215.1 - 3.3e-23 82.0 33.9 2.2e-21 76.0 33.9 3.1 1 1 0 1 1 1 1 Permease family DUF4956 PF16316.5 KPI36215.1 - 0.055 13.1 0.6 0.29 10.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) MFS_MOT1 PF16983.5 KPI36215.1 - 7.2 7.1 17.6 1 9.8 7.5 3.0 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily MFS_1 PF07690.16 KPI36216.1 - 1.5e-36 126.0 53.6 4.5e-36 124.5 52.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36216.1 - 1.5e-12 47.2 7.4 1.5e-12 47.2 7.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI36216.1 - 6.5e-11 41.4 28.0 1.5e-10 40.1 28.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3357 PF11837.8 KPI36216.1 - 3.9 8.0 4.5 2 8.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF1746 PF08508.10 KPI36217.1 - 2.5e-23 82.6 0.7 3.4e-23 82.2 0.7 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RNA_pol_Rpb4 PF03874.16 KPI36218.1 - 2.6e-16 60.0 0.8 3.5e-16 59.7 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 HOCHOB PF17943.1 KPI36218.1 - 0.089 13.5 0.1 0.2 12.4 0.1 1.5 1 1 0 1 1 1 0 Homeobox-cysteine loop-homeobox AA_permease_2 PF13520.6 KPI36219.1 - 3.5e-66 223.8 46.2 4.2e-66 223.5 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI36219.1 - 6.1e-18 64.7 31.5 8.2e-18 64.2 31.5 1.2 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.29 KPI36220.1 - 1.6e-35 122.4 0.0 3.3e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI36220.1 - 1.8e-05 24.5 0.1 4.9e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KPI36220.1 - 0.0055 16.8 0.1 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Peptidase_C78 PF07910.13 KPI36222.1 - 1.1e-43 149.2 0.0 1.4e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 DUF1815 PF08844.10 KPI36224.1 - 0.073 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Dioxygenase_C PF00775.21 KPI36225.1 - 1.8e-08 34.0 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Bromodomain PF00439.25 KPI36226.1 - 4.2e-34 116.5 0.9 2.5e-16 59.5 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Dus PF01207.17 KPI36227.1 - 8.3e-29 100.7 0.0 2e-28 99.4 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Brix PF04427.18 KPI36229.1 - 1.7e-29 103.3 0.0 2.3e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain SKG6 PF08693.10 KPI36230.1 - 0.0016 17.8 3.4 0.0035 16.7 3.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RCR PF12273.8 KPI36230.1 - 0.005 17.5 0.1 0.0088 16.7 0.1 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Stevor PF17410.2 KPI36230.1 - 0.012 15.1 0.4 0.017 14.7 0.4 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Podoplanin PF05808.11 KPI36230.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Podoplanin RIFIN PF02009.16 KPI36230.1 - 0.057 13.3 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Rifin Otopetrin PF03189.13 KPI36230.1 - 0.092 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Metallophos PF00149.28 KPI36231.1 - 2.9e-15 57.3 0.6 5.2e-15 56.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Yos1 PF08571.10 KPI36232.1 - 5.1e-28 97.2 0.1 7e-28 96.7 0.1 1.2 1 0 0 1 1 1 1 Yos1-like MTA_R1 PF17226.2 KPI36232.1 - 0.067 13.4 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 MTA R1 domain Dynamitin PF04912.14 KPI36233.1 - 1.2e-47 163.2 21.3 6.8e-47 160.6 21.3 1.9 1 1 0 1 1 1 1 Dynamitin DUF948 PF06103.11 KPI36233.1 - 0.05 13.9 0.2 6.1 7.2 0.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1192 PF06698.11 KPI36233.1 - 0.065 13.3 12.5 0.21 11.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) THOC7 PF05615.13 KPI36233.1 - 0.14 12.4 10.9 1.3 9.3 0.2 3.5 3 0 0 3 3 3 0 Tho complex subunit 7 CENP-H PF05837.12 KPI36233.1 - 0.15 12.4 10.5 4.5 7.7 4.5 3.4 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF1640 PF07798.11 KPI36233.1 - 0.27 11.3 3.2 1.1 9.3 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KPI36233.1 - 0.31 11.1 3.5 1.5 8.8 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KPI36233.1 - 0.43 10.6 4.5 31 4.6 0.5 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 KPI36233.1 - 0.92 9.8 0.0 0.92 9.8 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 KPI36233.1 - 1.1 7.8 7.4 2 6.9 1.8 2.2 2 0 0 2 2 2 0 AAA domain ATF7IP_BD PF16788.5 KPI36233.1 - 2.3 8.2 5.9 0.39 10.8 1.3 1.9 2 0 0 2 2 2 0 ATF-interacting protein binding domain Jnk-SapK_ap_N PF09744.9 KPI36233.1 - 3.7 7.8 13.5 4.3 7.6 0.1 3.4 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 KPI36233.1 - 5 7.5 9.9 8.6 6.8 0.8 3.1 3 0 0 3 3 3 0 Fez1 DUF4267 PF14087.6 KPI36234.1 - 3.5e-14 52.8 0.1 4e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DoxX PF07681.12 KPI36234.1 - 0.036 14.7 1.0 0.045 14.3 1.0 1.3 1 0 0 1 1 1 0 DoxX F-box-like_2 PF13013.6 KPI36235.1 - 0.073 13.0 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain NCBP3 PF10309.9 KPI36236.1 - 1e-18 66.9 0.1 1.8e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KPI36236.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain HET PF06985.11 KPI36237.1 - 2.2e-11 44.3 5.6 2.9e-10 40.7 0.6 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KPI36238.1 - 3.9e-80 269.5 0.0 4.9e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI36238.1 - 2.8e-08 34.6 0.1 5.9e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aa_trans PF01490.18 KPI36240.1 - 4.2e-23 81.7 38.9 4.9e-23 81.5 38.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5056 PF16479.5 KPI36240.1 - 5.6 7.3 8.5 0.72 10.1 0.3 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF5056) F-box-like PF12937.7 KPI36241.1 - 0.0039 17.0 0.0 0.009 15.9 0.0 1.6 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KPI36241.1 - 0.011 15.6 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain WSC PF01822.19 KPI36243.1 - 1.1e-37 128.1 20.5 3.4e-19 68.8 6.6 2.7 2 0 0 2 2 2 2 WSC domain zf-Paramyx-P PF13008.7 KPI36243.1 - 2.5 7.6 7.7 2.8 7.4 0.6 2.7 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Pkinase PF00069.25 KPI36244.1 - 4.2e-12 46.0 0.0 5.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KPI36244.1 - 0.0039 16.6 0.1 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KPI36244.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_1 PF07690.16 KPI36246.1 - 4.5e-31 108.1 41.8 4.5e-31 108.1 41.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI36246.1 - 1.1e-11 44.0 11.7 1.1e-11 44.0 11.7 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPI36246.1 - 1.8e-05 23.8 8.8 1.8e-05 23.8 8.8 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KPI36246.1 - 0.0054 15.2 4.1 0.011 14.2 4.1 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KPI36246.1 - 0.028 12.7 4.2 0.016 13.5 0.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family STALD PF18185.1 KPI36246.1 - 0.095 12.0 0.2 0.23 10.8 0.2 1.6 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family MFS_1 PF07690.16 KPI36247.1 - 1.8e-20 73.2 33.5 1.8e-20 73.2 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.17 KPI36247.1 - 0.052 12.6 0.9 1.6 7.7 0.7 2.2 2 0 0 2 2 2 0 CLN3 protein LacY_symp PF01306.19 KPI36247.1 - 5.1 5.8 13.4 0.34 9.6 0.4 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter Pkinase PF00069.25 KPI36248.1 - 1e-43 149.6 0.0 1.4e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36248.1 - 8.1e-17 61.4 0.0 1.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KPI36248.1 - 0.0027 17.3 0.4 0.0047 16.6 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KPI36248.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPI36248.1 - 0.024 14.0 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5405 PF17399.2 KPI36248.1 - 0.038 14.3 0.1 0.077 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) Aldo_ket_red PF00248.21 KPI36253.1 - 3.5e-39 134.8 0.0 4e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KPI36255.1 - 4.3e-44 149.0 7.0 8e-08 32.8 0.0 10.1 7 2 2 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI36255.1 - 4.3e-25 87.8 28.0 2.6e-08 34.2 0.0 13.6 13 2 4 17 17 17 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI36255.1 - 2e-23 82.1 6.3 9.5e-06 25.8 0.1 10.1 10 0 0 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI36255.1 - 4.5e-23 78.8 15.7 0.036 14.6 0.0 14.4 16 0 0 16 16 16 5 Ankyrin repeat Ank PF00023.30 KPI36255.1 - 4.6e-17 61.6 19.5 0.016 15.6 0.0 11.8 12 0 0 12 12 12 4 Ankyrin repeat NACHT PF05729.12 KPI36255.1 - 1.4e-05 25.1 0.0 7.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPI36255.1 - 0.00016 22.1 0.0 0.00055 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPI36255.1 - 0.025 14.8 0.0 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.24 KPI36256.1 - 8.1e-75 252.4 25.0 9.7e-75 252.1 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36256.1 - 8.4e-29 100.6 43.1 5.8e-28 97.8 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.10 KPI36256.1 - 3.2 7.6 4.5 0.58 10.0 0.3 1.9 2 1 1 3 3 3 0 Mitochondrial import protein Pam17 SLATT_3 PF18184.1 KPI36256.1 - 7.9 6.6 7.0 10 6.2 0.2 3.3 2 1 2 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 3 HET PF06985.11 KPI36258.1 - 1.1e-30 106.9 1.4 1.7e-30 106.3 1.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like_2 PF13013.6 KPI36259.1 - 0.0031 17.5 0.2 0.012 15.5 0.1 1.9 2 1 0 2 2 2 1 F-box-like domain F-box-like PF12937.7 KPI36259.1 - 0.0041 17.0 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI36259.1 - 0.053 13.4 0.8 0.72 9.8 0.8 2.5 1 1 0 1 1 1 0 F-box domain AMP-binding PF00501.28 KPI36260.1 - 2.1e-16 59.6 0.0 4.2e-16 58.6 0.0 1.5 1 1 1 2 2 2 1 AMP-binding enzyme Fungal_trans PF04082.18 KPI36262.1 - 1.8e-24 86.2 0.6 8.9e-24 83.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.13 KPI36263.1 - 2.7e-47 161.3 0.0 3.1e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36263.1 - 3.3e-13 49.9 0.0 5.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI36263.1 - 3.7e-06 27.2 0.1 0.00034 20.9 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI36263.1 - 0.00087 18.8 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI36263.1 - 0.0039 16.2 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KPI36263.1 - 0.024 15.1 0.2 0.15 12.5 0.1 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Nitroreductase PF00881.24 KPI36264.1 - 0.0017 18.4 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Cupin_1 PF00190.22 KPI36265.1 - 4.4e-37 127.0 0.1 2e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPI36265.1 - 8.1e-27 92.8 3.0 1.8e-14 53.2 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPI36265.1 - 2.6e-08 33.4 0.3 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPI36265.1 - 2.5e-05 24.2 0.9 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KPI36265.1 - 0.006 16.5 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 KPI36265.1 - 0.0085 15.8 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cpn10 PF00166.21 KPI36265.1 - 0.15 12.2 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Glyco_transf_90 PF05686.12 KPI36267.1 - 1.4e-16 60.5 1.0 1.8e-08 33.7 0.6 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 ECH_1 PF00378.20 KPI36269.1 - 4.5e-58 196.5 0.0 5.6e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI36269.1 - 8.4e-31 107.7 0.0 2.6e-27 96.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KPI36269.1 - 0.013 15.4 0.1 0.29 11.1 0.0 2.2 1 1 1 2 2 2 0 Peptidase family S49 Ank_2 PF12796.7 KPI36270.1 - 3.1e-29 101.4 6.7 1.5e-12 48.0 0.3 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KPI36270.1 - 1.7e-17 63.0 0.3 0.00028 21.2 0.2 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KPI36270.1 - 1.1e-16 61.0 1.0 1.3e-10 41.6 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI36270.1 - 7.2e-14 50.5 0.5 0.001 19.4 0.1 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KPI36270.1 - 1.1e-11 44.8 1.1 0.00018 21.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) CorA PF01544.18 KPI36270.1 - 0.1 11.9 1.4 1 8.6 1.4 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1896 PF08989.10 KPI36270.1 - 0.16 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) SUR7 PF06687.12 KPI36270.1 - 1.5 8.4 5.1 0.33 10.6 0.5 1.9 2 0 0 2 2 2 0 SUR7/PalI family Peptidase_S9 PF00326.21 KPI36271.1 - 2.5e-50 170.9 0.3 3.8e-50 170.3 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KPI36271.1 - 0.0016 18.3 1.9 0.11 12.4 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat RACo_C_ter PF14574.6 KPI36271.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Adeno_hexon PF01065.19 KPI36272.1 - 0.0016 17.4 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Hexon, adenovirus major coat protein, N-terminal domain BTB PF00651.31 KPI36273.1 - 1.3e-16 60.8 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NmrA PF05368.13 KPI36274.1 - 6.7e-32 110.9 0.0 8.3e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36274.1 - 4.3e-11 43.0 0.2 8.1e-11 42.1 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPI36274.1 - 6.4e-06 25.4 0.0 8.3e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPI36274.1 - 9.2e-06 25.3 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI36274.1 - 0.054 13.4 0.2 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KPI36274.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WLM PF08325.10 KPI36275.1 - 1.9e-46 158.6 7.4 2.3e-37 129.0 0.2 2.4 1 1 1 2 2 2 2 WLM domain zf-RanBP PF00641.18 KPI36275.1 - 0.0002 20.6 0.6 0.0002 20.6 0.6 2.8 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KPI36275.1 - 0.015 15.6 2.2 3.4 8.1 0.1 2.6 2 0 0 2 2 2 0 C1 domain PIF1 PF05970.14 KPI36275.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DZR PF12773.7 KPI36275.1 - 0.12 12.4 6.8 1.2 9.2 7.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KPI36275.1 - 0.15 12.9 1.5 2.4 8.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon family Zf_RING PF16744.5 KPI36275.1 - 0.27 11.4 0.1 0.27 11.4 0.1 3.3 2 1 1 3 3 3 0 KIAA1045 RING finger LGT PF01790.18 KPI36275.1 - 0.29 10.3 0.0 0.43 9.8 0.0 1.2 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase zf-ribbon_3 PF13248.6 KPI36275.1 - 7.4 6.1 6.9 7.4 6.1 3.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RecR PF02132.15 KPI36275.1 - 9.3 5.9 7.0 1.3 8.7 0.3 2.7 2 0 0 2 2 2 0 RecR protein CBP_BcsF PF11120.8 KPI36276.1 - 0.1 12.7 3.4 7.4 6.8 0.0 3.4 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF adh_short PF00106.25 KPI36277.1 - 1.4e-15 57.3 0.4 9.6e-14 51.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI36277.1 - 3.8e-07 30.2 0.1 5.7e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI36277.1 - 1.2e-06 28.3 0.3 6.1e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Aldedh PF00171.22 KPI36278.1 - 4.8e-146 486.9 1.6 1.1e-143 479.1 1.6 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Phage_attach PF05354.11 KPI36278.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage Head-Tail Attachment DUF1487 PF07368.11 KPI36278.1 - 0.18 11.3 0.0 0.87 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) CBAH PF02275.18 KPI36279.1 - 2.2e-33 116.3 0.1 7.5e-32 111.2 0.1 2.1 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Pro_isomerase PF00160.21 KPI36280.1 - 2.5e-39 135.1 0.4 3.1e-39 134.8 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_1 PF00300.22 KPI36281.1 - 1.8e-09 37.6 0.0 4.9e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1776 PF08643.10 KPI36283.1 - 1.5e-62 211.7 0.0 1.9e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TFIIA PF03153.13 KPI36283.1 - 0.13 12.2 1.3 0.2 11.6 1.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 KPI36284.1 - 4.5e-50 170.4 0.0 5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36284.1 - 1.4e-38 132.3 0.0 1.6e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36284.1 - 2.8e-08 33.9 0.0 4.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 KPI36284.1 - 0.077 12.8 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3752 PF12572.8 KPI36285.1 - 4e-43 147.6 12.8 4e-43 147.6 12.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 KPI36285.1 - 0.0094 15.3 1.5 0.014 14.8 1.5 1.2 1 0 0 1 1 1 1 Dynamitin Vta1 PF04652.16 KPI36286.1 - 2.5e-53 180.0 1.9 3.9e-53 179.3 1.9 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KPI36286.1 - 8.5e-15 54.2 0.0 1.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Vta1 C-terminal domain adh_short_C2 PF13561.6 KPI36287.1 - 4.1e-47 160.7 5.0 6e-30 104.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36287.1 - 2.9e-29 101.9 4.7 3.3e-17 62.6 1.5 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI36287.1 - 6.3e-07 29.5 2.0 5.9e-06 26.3 0.2 2.1 1 1 1 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KPI36287.1 - 0.02 14.3 0.2 0.045 13.1 0.1 1.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 KPI36287.1 - 0.094 12.6 0.1 0.2 11.5 0.1 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus Epimerase PF01370.21 KPI36287.1 - 0.14 11.6 0.4 0.21 11.0 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family IpaB_EvcA PF03278.13 KPI36287.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 IpaB/EvcA family Pro_racemase PF05544.11 KPI36288.1 - 8.3e-82 274.8 0.0 9.4e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 KPI36288.1 - 0.00022 20.8 0.0 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 Phenazine biosynthesis-like protein QueC PF06508.13 KPI36288.1 - 0.09 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Sugar_tr PF00083.24 KPI36291.1 - 2.4e-96 323.4 28.2 2.8e-96 323.1 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36291.1 - 1.3e-11 44.0 31.7 1.3e-11 44.0 31.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KPI36293.1 - 1.3e-34 117.8 0.1 3.1e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRI12 PF06609.13 KPI36293.1 - 6.3e-29 100.8 25.0 9.3e-29 100.3 25.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI36293.1 - 1.1e-21 77.2 50.6 1.2e-20 73.7 46.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36293.1 - 2.1e-09 36.8 6.4 2.1e-09 36.8 6.4 3.7 4 0 0 4 4 4 1 Sugar (and other) transporter Pox_A14 PF05767.12 KPI36293.1 - 0.11 12.6 0.9 0.5 10.6 0.8 2.2 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 Mitofilin PF09731.9 KPI36293.1 - 9.9 4.9 10.0 0.16 10.8 2.4 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Bac_luciferase PF00296.20 KPI36294.1 - 0.072 12.5 0.1 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 Luciferase-like monooxygenase F-box-like_2 PF13013.6 KPI36295.1 - 0.087 12.8 0.4 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain CBM_5_12_2 PF14600.6 KPI36296.1 - 0.71 9.8 3.5 0.5 10.3 0.5 2.3 2 1 0 2 2 2 0 Cellulose-binding domain Sugar_tr PF00083.24 KPI36299.1 - 7.6e-76 255.8 16.5 8.7e-76 255.6 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36299.1 - 9.1e-26 90.6 17.5 9.1e-26 90.6 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF986 PF06173.12 KPI36299.1 - 0.07 13.2 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF986) GNAT_acetyltr_2 PF13718.6 KPI36300.1 - 1.3e-97 325.7 0.0 3.5e-97 324.3 0.0 1.8 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KPI36300.1 - 6.8e-67 225.6 0.8 2.6e-66 223.7 0.8 2.0 1 1 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KPI36300.1 - 2.8e-65 219.5 0.0 1.5e-64 217.1 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KPI36300.1 - 3.1e-34 116.8 0.0 8.4e-34 115.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KPI36300.1 - 0.0024 17.6 0.0 0.11 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI36300.1 - 0.0031 17.8 0.1 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AA_permease PF00324.21 KPI36301.1 - 3e-136 454.8 38.9 3.4e-136 454.6 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI36301.1 - 1.5e-39 136.0 44.3 1.9e-39 135.7 44.3 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KPI36302.1 - 3.1e-65 220.8 17.5 1.1e-63 215.8 17.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36302.1 - 1.3e-10 40.7 30.3 4.9e-08 32.3 6.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2070 PF09843.9 KPI36302.1 - 0.35 9.1 5.0 0.67 8.2 5.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Aldo_ket_red PF00248.21 KPI36303.1 - 2.3e-61 207.6 0.0 2e-59 201.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3950 PF13132.6 KPI36303.1 - 0.064 13.0 0.3 0.17 11.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Aldedh PF00171.22 KPI36304.1 - 1.8e-176 587.2 0.0 2.1e-176 587.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BMC PF00936.19 KPI36304.1 - 0.098 12.7 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 BMC domain PAS_9 PF13426.7 KPI36306.1 - 7.5e-12 45.4 0.0 4e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain DUF5321 PF17254.2 KPI36307.1 - 4.8e-47 159.4 3.8 5.7e-47 159.1 3.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DDE_Tnp_IS240 PF13610.6 KPI36307.1 - 0.092 13.0 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 DDE domain DUF1479 PF07350.12 KPI36308.1 - 0.00093 18.1 0.0 0.057 12.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 KPI36308.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N PF00107.26 KPI36309.1 - 7.2e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FixS PF03597.15 KPI36311.1 - 0.12 12.1 1.6 0.44 10.3 1.6 2.0 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type CPT_N PF16484.5 KPI36313.1 - 3.4 7.7 5.8 10 6.2 0.2 3.2 3 0 0 3 3 3 0 Carnitine O-palmitoyltransferase N-terminus F-box-like_2 PF13013.6 KPI36314.1 - 0.013 15.4 0.0 0.035 14.1 0.0 1.7 1 1 0 1 1 1 0 F-box-like domain F-box-like_2 PF13013.6 KPI36316.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 F-box-like domain SNase PF00565.17 KPI36317.1 - 1.8e-21 76.6 0.5 5e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Staphylococcal nuclease homologue PHD_Oberon PF07227.11 KPI36318.1 - 2.3 8.1 10.1 2.9 7.8 3.2 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein DUF4440 PF14534.6 KPI36319.1 - 0.00024 21.4 0.1 0.048 14.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4267 PF14087.6 KPI36320.1 - 1.9e-17 63.3 1.8 3e-17 62.7 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Vma12 PF11712.8 KPI36320.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_hydro_76 PF03663.14 KPI36321.1 - 7.4e-131 437.0 22.7 8.6e-131 436.8 22.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPI36321.1 - 0.0047 16.1 3.2 0.0047 16.1 3.2 2.4 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 GST_C PF00043.25 KPI36323.1 - 1.8e-05 24.8 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI36323.1 - 0.0011 18.9 0.1 0.0042 17.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI36323.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AP_endonuc_2 PF01261.24 KPI36324.1 - 1.8e-30 106.0 0.5 2.4e-30 105.6 0.5 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 KPI36324.1 - 4.1e-11 42.4 0.2 7.2e-11 41.6 0.2 1.4 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus Transferase PF02458.15 KPI36325.1 - 4.4e-10 38.8 0.0 1.3e-07 30.7 0.0 2.8 1 1 1 2 2 2 2 Transferase family Elf4 PF07011.11 KPI36325.1 - 0.11 12.5 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Early Flowering 4 domain p450 PF00067.22 KPI36326.1 - 2.8e-55 187.9 0.0 4.1e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KPI36326.1 - 6e-15 55.6 0.1 6e-14 52.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI36326.1 - 1.5e-10 40.8 0.0 8e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI36326.1 - 3.2e-07 31.2 0.0 3.2e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KPI36326.1 - 0.0026 17.4 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Transferase PF02458.15 KPI36327.1 - 9.4e-21 74.0 0.0 9.6e-15 54.2 0.0 2.3 2 1 0 2 2 2 2 Transferase family Abhydrolase_1 PF00561.20 KPI36328.1 - 0.0066 16.1 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Med19 PF10278.9 KPI36329.1 - 0.28 11.1 3.6 0.41 10.6 1.2 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 F-box-like_2 PF13013.6 KPI36332.1 - 0.04 13.9 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain zf-RING_2 PF13639.6 KPI36333.1 - 9.1e-12 45.1 6.5 1.4e-11 44.6 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI36333.1 - 1.8e-08 34.1 6.2 2.8e-08 33.5 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI36333.1 - 8.8e-08 31.8 0.9 1.5e-07 31.1 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI36333.1 - 2.4e-07 30.5 3.6 3.9e-07 29.8 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPI36333.1 - 4.7e-06 26.8 9.6 2.2e-05 24.7 9.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KPI36333.1 - 1.2e-05 25.2 3.4 1.9e-05 24.5 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI36333.1 - 0.001 19.0 1.0 0.001 19.0 1.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KPI36333.1 - 0.0018 18.3 3.2 0.0042 17.1 3.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KPI36333.1 - 0.0058 16.5 2.6 0.01 15.7 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KPI36333.1 - 0.053 13.1 4.2 0.097 12.3 4.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KPI36333.1 - 0.08 12.8 6.3 0.14 12.0 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KPI36333.1 - 0.21 11.5 5.7 0.4 10.6 5.7 1.5 1 0 0 1 1 1 0 PHD-finger PAT1 PF09770.9 KPI36333.1 - 0.33 9.2 5.0 0.53 8.5 5.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RINGv PF12906.7 KPI36333.1 - 0.43 10.8 3.7 0.96 9.6 3.7 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KPI36333.1 - 0.44 10.7 4.7 0.96 9.7 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KPI36333.1 - 0.63 9.9 5.0 1.3 8.9 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 OAD_gamma PF04277.13 KPI36333.1 - 0.79 10.4 0.0 0.79 10.4 0.0 2.6 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Dicty_REP PF05086.12 KPI36333.1 - 2.7 5.9 5.3 3.6 5.4 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3H2C3 PF17122.5 KPI36333.1 - 2.8 8.1 5.3 5.6 7.1 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger DUF218 PF02698.17 KPI36334.1 - 7.5e-08 32.5 0.1 2e-07 31.1 0.0 1.8 2 1 0 2 2 2 1 DUF218 domain AA_permease_2 PF13520.6 KPI36336.1 - 9.7e-31 107.0 47.1 1.6e-27 96.4 30.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPI36336.1 - 4e-21 75.2 26.2 4e-21 75.2 26.2 2.0 1 1 1 2 2 2 1 Amino acid permease Solute_trans_a PF03619.16 KPI36337.1 - 1.9e-46 158.8 9.8 2.2e-46 158.5 9.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Fungal_trans_2 PF11951.8 KPI36339.1 - 8.5e-50 169.7 1.1 1.2e-49 169.2 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CBP_BcsN PF17038.5 KPI36340.1 - 0.065 12.6 0.3 0.082 12.3 0.3 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN Solute_trans_a PF03619.16 KPI36341.1 - 6.8e-40 137.3 13.9 8.7e-40 136.9 13.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SUR7 PF06687.12 KPI36341.1 - 1.7 8.2 11.6 0.067 12.8 1.1 2.6 2 1 0 2 2 2 0 SUR7/PalI family F-box-like_2 PF13013.6 KPI36342.1 - 0.05 13.6 0.1 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 F-box-like domain DUF3316 PF11777.8 KPI36343.1 - 0.11 12.6 0.4 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) VWA_2 PF13519.6 KPI36344.1 - 0.00011 22.8 0.0 0.0013 19.3 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KPI36344.1 - 0.0024 18.1 0.0 0.0092 16.2 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain ELO PF01151.18 KPI36346.1 - 4.7e-55 186.8 17.9 5.5e-55 186.6 17.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1240 PF06836.12 KPI36346.1 - 1.1 9.9 11.9 16 6.1 4.1 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF1240) GST_N_2 PF13409.6 KPI36348.1 - 2.5e-25 88.5 0.1 7.1e-25 87.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI36348.1 - 3.8e-10 39.7 0.0 9.7e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPI36348.1 - 1.7e-06 28.4 0.0 0.39 11.2 0.0 3.4 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KPI36348.1 - 0.0065 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI36348.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.6 KPI36349.1 - 9.1e-54 182.5 3.8 1.8e-53 181.5 3.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36349.1 - 3e-45 154.1 4.7 5.6e-45 153.2 4.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36349.1 - 9.8e-11 41.9 4.5 1.2e-09 38.3 4.5 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI36349.1 - 0.0011 18.2 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KPI36349.1 - 0.029 14.5 0.3 0.059 13.5 0.3 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain PEX11 PF05648.14 KPI36350.1 - 3.1e-24 85.7 0.1 3.5e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) adh_short PF00106.25 KPI36351.1 - 6e-24 84.6 0.0 8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36351.1 - 3.8e-21 75.7 0.0 5.3e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PC4 PF02229.16 KPI36352.1 - 1.9e-24 85.0 1.6 4.7e-23 80.6 0.4 2.5 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) DUF5638 PF18688.1 KPI36352.1 - 0.085 13.2 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Haem_degrading PF03928.14 KPI36353.1 - 5.9e-16 58.6 0.1 7.3e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Iron_permease PF04120.12 KPI36354.1 - 3.7e-28 97.9 9.6 1.2e-11 44.5 0.1 4.2 4 0 0 4 4 4 4 Low affinity iron permease V_ATPase_I PF01496.19 KPI36354.1 - 0.34 8.8 1.3 3.6 5.4 0.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4658 PF15555.6 KPI36354.1 - 0.43 10.7 6.0 2.1 8.5 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4658) DUF952 PF06108.12 KPI36355.1 - 1.6e-16 60.1 0.0 2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) FAF PF11250.8 KPI36355.1 - 0.074 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Fantastic Four meristem regulator NAD_binding_8 PF13450.6 KPI36356.1 - 0.00074 19.7 0.6 0.0031 17.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI36356.1 - 0.0022 18.0 0.1 0.11 12.5 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI36356.1 - 0.032 13.5 0.0 0.41 9.8 0.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KPI36356.1 - 0.065 12.6 0.1 22 4.3 0.1 3.2 4 0 0 4 4 4 0 ThiF family Shikimate_DH PF01488.20 KPI36356.1 - 0.098 12.7 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KPI36356.1 - 0.18 12.4 0.0 33 5.1 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L20 PF00453.18 KPI36357.1 - 0.08 13.0 0.0 0.08 13.0 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L20 Fungal_trans PF04082.18 KPI36359.1 - 2.6e-21 75.8 0.7 3.9e-21 75.3 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 KPI36360.1 - 1.2e-43 149.4 0.0 1.4e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI36360.1 - 4.3e-11 43.2 0.8 4.9e-08 33.4 0.5 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI36360.1 - 0.012 14.7 0.4 4.2 6.3 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 KPI36360.1 - 0.022 14.3 1.9 26 4.3 0.0 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KPI36360.1 - 0.039 14.4 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KPI36360.1 - 0.041 13.1 4.2 0.17 11.1 1.1 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI36360.1 - 0.042 12.6 0.4 15 4.2 0.0 3.4 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_8 PF13450.6 KPI36360.1 - 0.062 13.5 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI36360.1 - 0.078 12.0 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 KPI36360.1 - 0.098 12.9 0.4 18 5.6 0.1 2.7 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 KPI36360.1 - 0.62 9.1 2.3 9 5.2 1.1 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 KPI36362.1 - 1.8e-57 194.6 2.4 2.1e-57 194.4 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36362.1 - 1.4e-43 148.6 1.3 1.8e-43 148.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36362.1 - 1.3e-11 44.8 0.3 2.2e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI36362.1 - 0.079 12.4 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AstE_AspA PF04952.14 KPI36364.1 - 2.4e-26 92.5 0.0 3.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family FMO-like PF00743.19 KPI36365.1 - 3.5e-23 81.8 0.8 7.6e-23 80.7 0.2 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI36365.1 - 1.7e-08 34.0 0.0 8.8e-05 21.8 0.0 3.6 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI36365.1 - 6e-08 32.3 0.0 2.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI36365.1 - 4.5e-07 30.0 0.0 1.7e-05 24.9 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI36365.1 - 0.001 19.1 0.0 3 7.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding ARL2_Bind_BART PF11527.8 KPI36365.1 - 0.0013 18.9 0.3 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Pyr_redox_3 PF13738.6 KPI36365.1 - 0.0043 16.3 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PS_pyruv_trans PF04230.13 KPI36365.1 - 0.078 12.9 0.3 0.27 11.1 0.1 2.0 3 0 0 3 3 3 0 Polysaccharide pyruvyl transferase Thi4 PF01946.17 KPI36365.1 - 0.082 12.1 0.0 7 5.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family LEA_1 PF03760.15 KPI36366.1 - 0.048 14.3 1.0 0.22 12.2 1.0 2.1 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 ZapB PF06005.12 KPI36367.1 - 0.00028 21.3 16.6 0.0086 16.5 8.2 2.8 1 1 0 2 2 2 2 Cell division protein ZapB FlaC_arch PF05377.11 KPI36367.1 - 0.0011 19.3 8.0 0.062 13.7 0.7 3.0 2 1 1 3 3 3 2 Flagella accessory protein C (FlaC) JAKMIP_CC3 PF16034.5 KPI36367.1 - 0.0027 17.7 3.8 0.0027 17.7 3.8 2.1 1 1 0 2 2 2 1 JAKMIP CC3 domain bZIP_1 PF00170.21 KPI36367.1 - 0.003 17.6 21.5 0.51 10.5 2.1 3.6 3 1 1 4 4 3 3 bZIP transcription factor DUF3450 PF11932.8 KPI36367.1 - 0.0043 16.4 6.2 0.007 15.7 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Spc7 PF08317.11 KPI36367.1 - 0.0045 15.9 9.8 0.0066 15.4 9.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4795 PF16043.5 KPI36367.1 - 0.0056 16.3 4.3 0.0092 15.6 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DivIC PF04977.15 KPI36367.1 - 0.0065 16.2 17.2 0.54 10.1 2.2 3.3 1 1 2 3 3 3 1 Septum formation initiator BLOC1_2 PF10046.9 KPI36367.1 - 0.024 14.9 11.0 0.3 11.4 2.6 2.9 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 KPI36367.1 - 0.029 14.2 8.4 0.1 12.4 7.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.12 KPI36367.1 - 0.031 13.9 9.7 0.51 9.9 9.7 2.1 1 1 0 1 1 1 0 PspA/IM30 family MIS13 PF08202.11 KPI36367.1 - 0.041 13.2 9.5 2 7.6 9.4 2.8 1 1 0 1 1 1 0 Mis12-Mtw1 protein family TMF_DNA_bd PF12329.8 KPI36367.1 - 0.042 13.9 16.8 0.11 12.6 7.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 KPI36367.1 - 0.045 14.0 8.0 0.48 10.7 1.9 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.11 KPI36367.1 - 0.047 13.9 11.0 0.13 12.5 11.0 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ERM PF00769.19 KPI36367.1 - 0.053 13.3 14.7 0.13 12.0 14.7 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 KPI36367.1 - 0.054 13.9 5.7 0.092 13.2 5.7 1.3 1 0 0 1 1 1 0 Fez1 Leu_zip PF15294.6 KPI36367.1 - 0.061 12.8 10.9 0.52 9.8 11.1 2.0 1 1 0 1 1 1 0 Leucine zipper TMF_TATA_bd PF12325.8 KPI36367.1 - 0.062 13.5 9.1 0.15 12.3 8.9 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 KPI36367.1 - 0.071 13.3 1.6 0.12 12.5 0.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 KPI36367.1 - 0.084 13.2 15.9 0.043 14.2 11.1 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 KPI36367.1 - 0.092 12.1 11.9 0.2 11.0 11.9 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KPI36367.1 - 0.093 12.6 3.3 0.66 9.9 0.2 2.8 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Dor1 PF04124.12 KPI36367.1 - 0.11 11.1 2.1 0.16 10.6 1.6 1.5 1 1 0 1 1 1 0 Dor1-like family DHR10 PF18595.1 KPI36367.1 - 0.18 11.9 10.1 0.3 11.1 9.5 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Ax_dynein_light PF10211.9 KPI36367.1 - 0.18 11.7 13.1 1.7 8.6 3.7 2.7 1 1 1 2 2 2 0 Axonemal dynein light chain UPF0242 PF06785.11 KPI36367.1 - 0.18 11.9 3.9 0.31 11.1 3.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KPI36367.1 - 0.18 11.9 9.7 0.36 10.9 9.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KPI36367.1 - 0.19 12.4 6.9 0.5 11.0 1.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 KPI36367.1 - 0.19 11.8 19.0 1.3 9.2 1.8 3.9 2 1 1 3 3 3 0 Basic region leucine zipper DUF334 PF03904.13 KPI36367.1 - 0.2 11.2 3.6 0.25 10.9 2.7 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF334) TPR_MLP1_2 PF07926.12 KPI36367.1 - 0.2 11.7 13.6 0.21 11.7 5.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.6 KPI36367.1 - 0.24 10.9 14.1 0.22 11.1 5.1 2.2 1 1 1 2 2 2 0 TMCO5 family Cnn_1N PF07989.11 KPI36367.1 - 0.25 11.5 13.5 0.53 10.5 6.0 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 KPI36367.1 - 0.3 11.2 3.1 3.6 7.6 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KPI36367.1 - 0.36 9.3 0.4 0.49 8.9 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 KPI36367.1 - 0.39 10.5 12.1 1.4 8.7 12.1 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CLZ PF16526.5 KPI36367.1 - 0.45 10.9 9.7 2.9 8.3 1.0 2.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAP1_N PF04849.13 KPI36367.1 - 0.71 9.0 13.0 2.3 7.3 13.0 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region MerR-DNA-bind PF09278.11 KPI36367.1 - 1 10.0 3.8 2.1 9.0 0.4 2.6 1 1 1 2 2 2 0 MerR, DNA binding Swi5 PF07061.11 KPI36367.1 - 1.1 9.4 5.7 7.8 6.7 0.5 2.8 1 1 0 2 2 2 0 Swi5 Shugoshin_N PF07558.11 KPI36367.1 - 1.1 9.1 11.7 11 6.0 0.1 3.8 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region AAA_13 PF13166.6 KPI36367.1 - 1.3 7.6 6.9 0.78 8.3 2.0 2.0 1 1 1 2 2 2 0 AAA domain KfrA_N PF11740.8 KPI36367.1 - 1.5 9.5 8.9 3.8 8.2 0.6 3.1 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term DUF5082 PF16888.5 KPI36367.1 - 1.6 9.0 6.9 26 5.1 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ACCA PF03255.14 KPI36367.1 - 2 8.3 6.0 2.7 7.9 1.8 2.4 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_GP20 PF06810.11 KPI36367.1 - 2 8.2 10.2 29 4.4 9.6 2.4 2 1 1 3 3 2 0 Phage minor structural protein GP20 BRI3BP PF14965.6 KPI36367.1 - 2.2 7.8 8.2 5.9 6.4 1.0 2.9 2 1 2 4 4 3 0 Negative regulator of p53/TP53 DUF4140 PF13600.6 KPI36367.1 - 2.2 8.8 7.2 36 4.9 0.9 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4618 PF15397.6 KPI36367.1 - 2.3 7.6 9.0 9.2 5.6 0.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HAUS6_N PF14661.6 KPI36367.1 - 2.5 7.6 6.9 5.5 6.5 3.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cep57_CLD_2 PF14197.6 KPI36367.1 - 3 8.0 17.5 2.1 8.5 1.9 3.5 3 1 0 4 4 3 0 Centrosome localisation domain of PPC89 ABC_tran_CTD PF16326.5 KPI36367.1 - 3.1 8.1 14.5 11 6.3 0.8 3.7 2 1 2 4 4 3 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 KPI36367.1 - 3.3 7.9 17.0 39 4.4 17.0 2.2 1 1 0 1 1 1 0 Tropomyosin like Syntaxin-6_N PF09177.11 KPI36367.1 - 4.2 8.0 6.5 46 4.6 5.7 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal XhlA PF10779.9 KPI36367.1 - 4.3 7.6 8.5 11 6.4 1.4 2.4 1 1 1 2 2 2 0 Haemolysin XhlA HALZ PF02183.18 KPI36367.1 - 4.7 7.5 14.6 0.78 10.0 2.4 2.9 3 0 0 3 3 2 0 Homeobox associated leucine zipper MRPL52 PF18699.1 KPI36367.1 - 4.8 7.4 10.5 0.79 9.9 0.8 2.6 1 1 0 2 2 2 0 Mitoribosomal protein mL52 TMPIT PF07851.13 KPI36367.1 - 5.3 6.2 4.9 7.6 5.7 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 KPI36367.1 - 5.3 7.3 12.8 4.2 7.6 5.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAM76 PF16046.5 KPI36367.1 - 5.8 6.2 8.0 9.9 5.4 8.0 1.4 1 1 0 1 1 1 0 FAM76 protein DUF1192 PF06698.11 KPI36367.1 - 5.9 7.0 13.9 12 6.0 2.2 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1192) Atg14 PF10186.9 KPI36367.1 - 7.6 5.5 9.2 16 4.5 8.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KPI36367.1 - 9.8 6.5 9.7 31 4.9 9.7 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) E1-E2_ATPase PF00122.20 KPI36369.1 - 3.7e-39 134.1 18.2 4e-35 121.0 10.5 4.2 3 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPI36369.1 - 2.8e-28 98.9 1.1 2.8e-28 98.9 1.1 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPI36369.1 - 7.5e-19 68.9 2.3 2.7e-17 63.8 1.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI36369.1 - 1.1e-15 57.0 0.0 2.5e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPI36369.1 - 5.5e-14 52.0 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPI36369.1 - 3.1e-08 33.7 1.2 2.4e-06 27.5 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPI36369.1 - 0.0081 16.6 0.1 0.017 15.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase IncE PF17627.2 KPI36369.1 - 0.011 15.7 1.9 0.046 13.7 1.9 2.1 1 0 0 1 1 1 0 Inclusion membrane protein E ADH_N PF08240.12 KPI36370.1 - 3.6e-25 88.0 3.5 3.6e-25 88.0 3.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KPI36370.1 - 0.0023 17.8 0.0 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Asp PF00026.23 KPI36371.1 - 7.3e-06 25.6 0.0 2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease 4HBT PF03061.22 KPI36372.1 - 2.6e-10 40.5 0.0 6.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily His_Phos_2 PF00328.22 KPI36373.1 - 1.1e-10 41.5 0.0 1.5e-08 34.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) UPF0016 PF01169.19 KPI36373.1 - 0.71 10.2 5.6 2.4 8.6 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 Ecm33 PF12454.8 KPI36373.1 - 5.3 7.3 5.8 0.47 10.6 0.2 2.2 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Rad60-SLD PF11976.8 KPI36374.1 - 3.9e-20 71.4 0.3 4.6e-20 71.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KPI36374.1 - 9.4e-10 38.1 0.1 1.1e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family 5-nucleotidase PF06189.12 KPI36374.1 - 0.11 11.4 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 5'-nucleotidase NTP_transf_9 PF04248.12 KPI36376.1 - 1e-36 124.7 0.0 6.4e-28 96.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF1772 PF08592.11 KPI36378.1 - 3.4e-09 37.1 0.7 4.3e-09 36.8 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PAS_9 PF13426.7 KPI36379.1 - 2.9e-17 62.8 0.0 9.5e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KPI36379.1 - 0.00025 21.0 0.0 0.0008 19.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KPI36379.1 - 0.0022 18.2 0.0 0.0091 16.2 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KPI36379.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold Glyco_hydro_61 PF03443.14 KPI36380.1 - 0.00064 19.7 0.0 0.00094 19.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KPI36380.1 - 0.017 15.8 0.0 0.023 15.4 0.0 1.2 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading HET PF06985.11 KPI36381.1 - 7.2e-30 104.3 0.0 1.4e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HIT PF01230.23 KPI36383.1 - 9.1e-19 68.0 0.1 1.7e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KPI36383.1 - 0.0023 18.4 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CHCH PF06747.13 KPI36384.1 - 5e-07 29.7 8.7 1e-05 25.5 1.2 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KPI36384.1 - 0.00015 21.7 3.2 0.0063 16.5 0.5 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KPI36384.1 - 0.01 15.8 8.7 0.5 10.4 0.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KPI36384.1 - 0.054 13.8 6.9 6.5 7.1 0.1 3.0 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 KPI36384.1 - 4.5 7.6 7.9 22 5.4 6.9 2.4 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein ABC_tran PF00005.27 KPI36386.1 - 0.018 15.6 0.0 0.094 13.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KPI36386.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glycogen_syn PF05693.13 KPI36387.1 - 4.3e-265 881.2 0.3 2e-219 730.4 0.0 2.0 1 1 1 2 2 2 2 Glycogen synthase Glyco_transf_4 PF13439.6 KPI36387.1 - 6.1e-05 23.1 0.1 0.00014 22.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KPI36387.1 - 0.00021 21.1 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KPI36387.1 - 0.0016 18.9 0.1 0.0034 17.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Peptidase_M91 PF14891.6 KPI36388.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 Effector protein DUF4344 PF14247.6 KPI36388.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase GMC_oxred_N PF00732.19 KPI36389.1 - 1.4e-56 192.0 0.0 1.9e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI36389.1 - 3.5e-35 121.6 0.0 1.6e-34 119.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KPI36389.1 - 2.5e-05 24.4 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI36389.1 - 0.0021 17.2 0.8 0.013 14.6 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KPI36389.1 - 0.016 14.3 0.2 0.055 12.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI36389.1 - 0.062 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tom5 PF10642.9 KPI36390.1 - 1.4e-18 66.6 0.1 1.5e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase F-box-like PF12937.7 KPI36391.1 - 0.0001 22.1 0.3 0.00027 20.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like dCMP_cyt_deam_1 PF00383.23 KPI36392.1 - 1.1e-09 38.1 0.1 1.5e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPI36392.1 - 7.4e-05 22.5 0.0 9.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KPI36392.1 - 0.033 14.3 0.2 0.055 13.6 0.2 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 WD40 PF00400.32 KPI36393.1 - 3.2e-39 132.2 20.2 2.3e-07 31.4 0.2 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KPI36393.1 - 1.4e-29 102.9 2.6 2e-29 102.4 2.6 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KPI36393.1 - 1.7e-10 41.0 1.2 0.016 15.4 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KPI36393.1 - 3.4e-06 26.8 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KPI36393.1 - 3.8e-05 23.7 0.1 0.00098 19.0 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KPI36393.1 - 0.0059 15.4 0.0 1.1 7.9 0.0 2.8 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.8 KPI36393.1 - 0.0093 14.7 1.5 0.047 12.3 0.1 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 DUF4550 PF15084.6 KPI36393.1 - 0.05 14.0 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) RAB3GAP2_N PF14655.6 KPI36393.1 - 0.07 12.4 0.0 0.22 10.7 0.0 1.8 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 KPI36393.1 - 0.19 11.0 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 KPI36393.1 - 0.25 10.2 0.3 0.49 9.3 0.3 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain polyprenyl_synt PF00348.17 KPI36394.1 - 1e-88 296.7 0.0 1.2e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LolA_2 PF16584.5 KPI36394.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Wtap PF17098.5 KPI36394.1 - 0.37 10.7 2.5 0.67 9.9 2.5 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family ILVD_EDD PF00920.21 KPI36395.1 - 1.7e-192 640.7 8.0 5.8e-102 341.9 2.5 2.0 1 1 1 2 2 2 2 Dehydratase family 4HBT_2 PF13279.6 KPI36396.1 - 1.3e-07 32.1 0.0 2.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily WW PF00397.26 KPI36397.1 - 6.7e-07 29.3 3.8 1.5e-06 28.2 3.8 1.6 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KPI36397.1 - 0.014 15.7 0.4 0.042 14.2 0.4 1.8 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f DUF1799 PF08809.11 KPI36397.1 - 0.059 13.6 1.2 0.12 12.5 1.2 1.5 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) DUF4512 PF14975.6 KPI36397.1 - 0.2 12.5 0.2 0.2 12.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4512) Ligase_CoA PF00549.19 KPI36399.1 - 1.1e-31 109.8 0.4 6.2e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 KPI36399.1 - 2.5e-12 47.3 0.2 7.6e-12 45.8 0.2 1.9 1 0 0 1 1 1 1 CoA binding domain MmgE_PrpD PF03972.14 KPI36401.1 - 1.8e-92 310.2 0.3 7.8e-59 199.4 2.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family NDK PF00334.19 KPI36402.1 - 6.4e-54 181.6 0.0 7.3e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ank_5 PF13857.6 KPI36403.1 - 1.3e-07 31.7 0.4 1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPI36403.1 - 1.6e-05 25.4 0.1 6.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI36403.1 - 2.9e-05 24.6 0.1 5e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPI36403.1 - 4.4e-05 23.6 0.3 0.0013 19.0 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KPI36403.1 - 0.0036 17.7 0.5 0.023 15.1 0.3 2.3 2 0 0 2 2 2 1 Ankyrin repeat Metallophos_2 PF12850.7 KPI36404.1 - 2.5e-13 50.6 0.0 3.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.31 KPI36405.1 - 2.1e-11 44.0 0.1 4.5e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain IMUP PF15761.5 KPI36405.1 - 0.023 15.4 1.4 0.044 14.5 1.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein G10 PF01125.17 KPI36405.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 G10 protein Ribosomal_L4 PF00573.22 KPI36406.1 - 5.9e-37 127.2 0.6 7.9e-37 126.8 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KPI36406.1 - 1.6e-29 101.7 0.5 1.6e-29 101.7 0.5 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_transf_21 PF13506.6 KPI36407.1 - 6.5e-16 58.3 0.0 6.4e-08 32.3 0.0 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KPI36407.1 - 3.5e-05 23.8 0.0 8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI36407.1 - 0.014 15.2 0.0 0.16 11.8 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 zf-C2H2 PF00096.26 KPI36408.1 - 1.2e-05 25.5 11.9 0.00015 22.0 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI36408.1 - 7.8e-05 22.9 2.1 7.8e-05 22.9 2.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KPI36408.1 - 0.00057 20.2 10.3 0.00098 19.4 1.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KPI36408.1 - 0.00094 19.8 9.0 0.00095 19.8 1.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI36408.1 - 0.0047 17.2 3.1 0.014 15.6 3.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KPI36408.1 - 0.11 12.8 5.7 0.18 12.1 5.7 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KPI36408.1 - 0.41 10.7 4.8 0.2 11.7 0.9 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Apt1 PF10351.9 KPI36408.1 - 7.4 5.3 10.3 0.46 9.3 3.7 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain PTS_2-RNA PF01885.16 KPI36409.1 - 2.6e-57 193.8 0.0 1.7e-56 191.1 0.0 2.0 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Clr5 PF14420.6 KPI36410.1 - 8.7e-15 54.7 0.0 1.4e-13 50.9 0.0 2.6 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.6 KPI36410.1 - 0.061 13.6 1.1 0.31 11.4 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI36410.1 - 0.071 13.3 0.3 0.071 13.3 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NmrA PF05368.13 KPI36411.1 - 5e-23 81.9 3.2 2.2e-14 53.6 0.0 4.0 2 2 0 2 2 2 2 NmrA-like family FAD_binding_2 PF00890.24 KPI36412.1 - 8.2e-122 407.3 4.6 2e-121 406.0 4.6 1.8 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KPI36412.1 - 1.3e-38 131.8 1.1 1.3e-38 131.8 1.1 3.0 3 0 0 3 3 3 1 Fumarate reductase flavoprotein C-term Dynamin_N PF00350.23 KPI36412.1 - 1.7e-17 64.0 0.2 1.4e-15 57.8 0.0 2.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KPI36412.1 - 7e-06 26.1 0.0 0.00018 21.6 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DAO PF01266.24 KPI36412.1 - 8.7e-06 25.5 0.5 0.0007 19.3 0.4 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase ABC_tran PF00005.27 KPI36412.1 - 1.8e-05 25.3 0.0 8.2e-05 23.1 0.0 2.3 1 0 0 1 1 1 1 ABC transporter Pyr_redox_2 PF07992.14 KPI36412.1 - 0.00032 20.0 5.7 0.0072 15.6 0.5 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AAA_16 PF13191.6 KPI36412.1 - 0.0033 17.8 0.2 0.02 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain FAD_binding_3 PF01494.19 KPI36412.1 - 0.0038 16.5 0.7 0.0086 15.4 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain RsgA_GTPase PF03193.16 KPI36412.1 - 0.0043 17.0 0.1 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Thi4 PF01946.17 KPI36412.1 - 0.0051 16.1 2.5 0.033 13.4 0.2 2.9 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 KPI36412.1 - 0.024 13.7 2.8 0.12 11.5 2.8 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A IIGP PF05049.13 KPI36412.1 - 0.087 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KPI36412.1 - 0.12 12.7 0.0 0.58 10.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.6 KPI36412.1 - 0.17 11.1 1.1 0.57 9.4 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DASH_Dad2 PF08654.10 KPI36412.1 - 0.2 12.1 4.9 0.66 10.4 0.9 3.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 HI0933_like PF03486.14 KPI36412.1 - 0.33 9.6 2.8 0.76 8.4 0.8 2.5 3 0 0 3 3 3 0 HI0933-like protein DUF1664 PF07889.12 KPI36412.1 - 8.6 6.4 11.3 3.5 7.7 1.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) LysM PF01476.20 KPI36413.1 - 3.9e-08 33.2 0.3 5.8e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 LysM domain Methyltransf_16 PF10294.9 KPI36415.1 - 1.5e-42 145.3 0.0 1.9e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KPI36415.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KPI36415.1 - 0.053 14.2 0.0 0.092 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.31 KPI36417.1 - 5.9e-12 45.8 0.1 2.1e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain TauD PF02668.16 KPI36418.1 - 3e-27 96.1 0.1 4.2e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KPI36418.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 CsiD Baculo_E56 PF04639.12 KPI36418.1 - 0.053 12.8 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF3402 PF11882.8 KPI36419.1 - 3.2e-161 537.5 0.0 4.8e-161 537.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KPI36419.1 - 6.2e-74 248.8 0.1 9.2e-74 248.2 0.1 1.3 1 0 0 1 1 1 1 N1221-like protein HLH PF00010.26 KPI36420.1 - 5.6e-11 42.2 0.0 1.7e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_31 PF01055.26 KPI36421.1 - 9.6e-132 440.3 5.7 1.6e-131 439.5 5.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Alk_phosphatase PF00245.20 KPI36421.1 - 1e-63 215.8 0.3 1.3e-62 212.1 0.3 2.1 1 1 0 1 1 1 1 Alkaline phosphatase Gal_mutarotas_2 PF13802.6 KPI36421.1 - 2.5e-22 78.9 0.6 1.5e-21 76.5 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KPI36421.1 - 1.4e-07 31.7 0.5 1.4e-07 31.7 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Sulfatase PF00884.23 KPI36421.1 - 3.5e-06 26.6 0.1 6.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPI36421.1 - 1.4e-05 24.8 0.1 2.8e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KPI36421.1 - 0.0025 17.2 0.7 0.82 9.0 0.1 2.3 2 0 0 2 2 2 2 Metalloenzyme superfamily DUF229 PF02995.17 KPI36421.1 - 0.0051 15.5 0.0 0.0091 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Got1 PF04178.12 KPI36422.1 - 2.3e-37 127.8 15.8 3e-37 127.5 15.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KPI36422.1 - 2 6.6 6.6 2.5 6.3 6.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DLH PF01738.18 KPI36423.1 - 4.8e-17 62.2 0.0 3e-07 30.2 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Velvet PF11754.8 KPI36424.1 - 2.7e-06 27.5 1.4 4.4e-06 26.8 1.4 1.4 1 1 0 1 1 1 1 Velvet factor p450 PF00067.22 KPI36426.1 - 4.6e-60 203.7 0.0 5.5e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CAP_N PF01213.19 KPI36427.1 - 1.5 8.2 5.2 0.33 10.4 0.2 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Cation_ATPase_C PF00689.21 KPI36428.1 - 1.4e-47 161.8 9.3 1.4e-47 161.8 9.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPI36428.1 - 3.3e-35 121.2 0.3 3.3e-35 121.2 0.3 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPI36428.1 - 2.5e-22 78.7 0.0 4.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPI36428.1 - 1.6e-21 77.5 0.0 4.9e-21 76.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI36428.1 - 2.5e-06 27.1 0.2 3e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI36428.1 - 3.9e-05 23.5 1.5 6.4e-05 22.8 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KPI36428.1 - 0.0024 16.8 3.6 0.1 11.4 3.5 2.6 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG FliMN_C PF01052.20 KPI36428.1 - 0.12 12.3 0.1 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term SMN PF06003.12 KPI36429.1 - 0.049 12.9 5.3 0.29 10.4 0.1 2.6 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) RHD3 PF05879.12 KPI36430.1 - 0 1035.7 0.0 0 1035.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KPI36430.1 - 1.3e-08 34.5 0.5 2.1e-08 33.7 0.5 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KPI36430.1 - 2.7e-05 24.2 0.1 6.7e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KPI36430.1 - 3.6e-05 23.9 0.0 7.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 KPI36430.1 - 0.0005 20.3 0.0 0.002 18.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KPI36430.1 - 0.026 13.8 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Septin ABC_ATPase PF09818.9 KPI36430.1 - 0.071 11.9 0.0 8.3 5.1 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 KPI36430.1 - 0.081 13.4 1.2 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1761 PF08570.10 KPI36432.1 - 1.4e-25 90.0 2.4 1.6e-25 89.8 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CoA_transf_3 PF02515.17 KPI36433.1 - 7.2e-65 219.5 0.0 7e-64 216.3 0.0 1.9 1 1 0 1 1 1 1 CoA-transferase family III GATase_2 PF00310.21 KPI36434.1 - 1.2e-178 594.2 0.0 1.6e-178 593.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KPI36434.1 - 7e-156 519.0 0.1 1.6e-154 514.5 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KPI36434.1 - 5.2e-115 383.7 0.0 2.2e-112 375.1 0.0 2.3 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 KPI36434.1 - 1.1e-85 286.1 3.4 1.8e-85 285.3 3.4 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KPI36434.1 - 6.1e-23 81.5 0.0 3.5e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KPI36434.1 - 2.1e-21 75.8 0.1 4.2e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KPI36434.1 - 1.9e-08 34.4 0.0 7.5e-08 32.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI36434.1 - 7.3e-08 32.9 0.0 0.00036 21.0 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI36434.1 - 1.2e-06 28.1 0.1 2.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KPI36434.1 - 6.5e-06 25.6 0.2 0.035 13.3 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI36434.1 - 1.5e-05 24.8 0.9 0.0048 16.5 0.4 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI36434.1 - 3.1e-05 22.8 0.2 6.6e-05 21.8 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KPI36434.1 - 8e-05 21.9 0.2 0.00077 18.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KPI36434.1 - 0.00013 21.4 0.1 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KPI36434.1 - 0.00013 21.4 0.2 0.00026 20.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 KPI36434.1 - 0.0015 17.0 0.0 0.064 11.7 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 KPI36434.1 - 0.0019 18.6 1.4 1.1 9.7 0.0 2.9 3 0 0 3 3 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KPI36434.1 - 0.0029 17.0 0.3 0.59 9.4 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 KPI36434.1 - 0.0095 15.0 1.8 0.054 12.5 1.7 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Thi4 PF01946.17 KPI36434.1 - 0.013 14.8 0.2 0.045 13.0 0.1 2.0 2 0 0 2 2 2 0 Thi4 family MADF_DNA_bdg PF10545.9 KPI36434.1 - 0.024 14.9 1.1 0.067 13.5 1.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 2-Hacid_dh_C PF02826.19 KPI36434.1 - 0.039 13.3 0.5 0.097 12.0 0.1 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPI36434.1 - 0.061 13.4 0.2 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KPI36434.1 - 0.072 12.7 0.1 0.26 10.9 0.1 1.9 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 KPI36434.1 - 0.21 10.7 3.0 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A XPA_C PF05181.12 KPI36436.1 - 2.7e-25 88.1 2.1 5.8e-25 87.0 2.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KPI36436.1 - 5.7e-06 26.3 1.2 5.7e-06 26.3 1.2 2.0 2 0 0 2 2 2 1 XPA protein N-terminal ADD_DNMT3 PF17980.1 KPI36436.1 - 0.065 13.2 0.3 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 YhfH PF14149.6 KPI36436.1 - 0.24 11.4 2.3 0.74 9.8 0.1 2.5 2 0 0 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.10 KPI36436.1 - 1.8 8.8 6.9 1.4 9.1 0.2 3.2 4 0 0 4 4 4 0 Zinc ribbon domain ArfGap PF01412.18 KPI36436.1 - 2.2 8.4 8.2 0.29 11.2 0.9 2.7 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Pyr_redox_2 PF07992.14 KPI36437.1 - 8.3e-07 28.5 0.1 3.1e-05 23.4 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI36437.1 - 0.03 13.6 0.1 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SRA1 PF07304.11 KPI36438.1 - 0.2 11.5 2.2 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) SAT PF16073.5 KPI36439.1 - 1.2e-69 234.7 0.7 4.5e-69 232.8 0.1 2.3 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KPI36439.1 - 1.7e-59 201.5 0.6 8e-58 196.0 0.6 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPI36439.1 - 2e-35 121.3 0.0 6.6e-35 119.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KPI36439.1 - 8.5e-35 120.8 0.0 1.4e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 KPI36439.1 - 1.9e-21 76.2 7.3 2.4e-12 47.0 0.7 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KPI36439.1 - 3.3e-19 69.9 0.0 1.5e-18 67.8 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KPI36439.1 - 3.5e-09 36.3 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KPI36439.1 - 3.8e-06 27.3 0.0 9.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KPI36439.1 - 5e-06 27.3 0.1 0.0043 17.7 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.23 KPI36439.1 - 0.0004 19.8 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Mito_carr PF00153.27 KPI36440.1 - 1.7e-66 220.2 0.9 2.7e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB PF00651.31 KPI36441.1 - 4.2e-15 55.9 0.0 8.3e-15 55.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_60s PF00428.19 KPI36441.1 - 0.4 11.3 4.9 0.49 11.0 3.6 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein HTH_CodY PF08222.11 KPI36442.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain Med26 PF08711.11 KPI36444.1 - 2.8e-11 43.2 0.0 7.2e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF1152 PF06626.12 KPI36445.1 - 0.0011 18.3 3.3 0.41 9.8 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1152) SUI1 PF01253.22 KPI36447.1 - 2.3e-22 79.3 0.0 4.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KPI36447.1 - 2.7e-09 37.6 1.1 5.4e-08 33.4 1.1 2.5 1 1 0 1 1 1 1 Pre-PUA-like domain Nup84_Nup100 PF04121.13 KPI36448.1 - 2.4e-102 343.4 6.2 2.3e-99 333.5 6.2 3.0 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Bacillus_HBL PF05791.11 KPI36448.1 - 0.043 13.6 0.2 0.099 12.5 0.2 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Phage_Mu_Gam PF07352.12 KPI36450.1 - 7.4e-05 22.7 6.1 7.4e-05 22.7 6.1 2.1 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein RST PF12174.8 KPI36450.1 - 0.076 12.9 0.3 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Baculo_PEP_C PF04513.12 KPI36450.1 - 0.085 12.9 6.5 0.48 10.4 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metal_resist PF13801.6 KPI36450.1 - 0.61 10.3 8.4 2.5 8.3 0.6 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Rrp44_S1 PF17215.3 KPI36450.1 - 0.98 9.4 5.7 0.35 10.9 1.7 2.2 2 1 0 2 2 2 0 S1 domain DUF948 PF06103.11 KPI36450.1 - 1 9.6 7.2 6 7.2 1.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) IPP-2 PF04979.14 KPI36451.1 - 1.5e-21 77.5 12.2 1.5e-21 77.5 12.2 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Glyco_transf_20 PF00982.21 KPI36452.1 - 3.6e-156 520.6 0.0 4.1e-156 520.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KPI36452.1 - 0.068 12.7 0.0 1.7 8.1 0.0 3.0 4 0 0 4 4 4 0 Glycosyl transferases group 1 Ank_5 PF13857.6 KPI36454.1 - 3.6e-16 59.0 0.2 9.6e-10 38.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI36454.1 - 7.1e-16 58.6 0.2 9.4e-15 55.0 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI36454.1 - 6.7e-15 55.3 0.5 1.2e-11 44.9 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPI36454.1 - 2.1e-14 53.2 0.8 7e-08 32.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KPI36454.1 - 1.9e-13 49.3 0.3 1.9e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Velvet PF11754.8 KPI36456.1 - 2.8e-41 142.1 1.1 1.6e-29 103.6 0.0 3.4 2 2 1 3 3 3 2 Velvet factor DUF4524 PF15025.6 KPI36457.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) CsbD PF05532.12 KPI36459.1 - 0.017 15.0 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 CsbD-like Mucin PF01456.17 KPI36459.1 - 3.4 7.7 10.8 4.3 7.3 10.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Cyclase PF04199.13 KPI36460.1 - 4.2e-16 59.4 0.1 3.2e-15 56.6 0.1 2.1 1 1 0 1 1 1 1 Putative cyclase Tau95_N PF17682.1 KPI36462.1 - 1e-27 96.9 0.1 1.9e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 KPI36462.1 - 4.6e-24 85.8 0.3 9.8e-24 84.8 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DAGK_cat PF00781.24 KPI36462.1 - 0.035 13.7 0.4 0.14 11.8 0.2 1.9 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain DUF3824 PF12868.7 KPI36464.1 - 0.024 15.3 1.7 0.024 15.3 1.7 8.9 3 3 4 7 7 7 0 Domain of unknwon function (DUF3824) HIG_1_N PF04588.13 KPI36465.1 - 2.5e-05 24.4 0.4 5.4e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region AIM24 PF01987.17 KPI36466.1 - 2.4e-47 161.3 0.1 2.9e-47 161.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Spt20 PF12090.8 KPI36466.1 - 3.1 7.4 22.9 4.3 6.9 22.9 1.1 1 0 0 1 1 1 0 Spt20 family HD PF01966.22 KPI36467.1 - 0.0026 18.0 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 HD domain YtzH PF14165.6 KPI36467.1 - 0.14 12.5 0.2 0.33 11.4 0.2 1.6 1 0 0 1 1 1 0 YtzH-like protein BTB PF00651.31 KPI36468.1 - 9.3e-15 54.8 0.3 3.6e-13 49.7 0.3 2.3 1 1 0 1 1 1 1 BTB/POZ domain NmrA PF05368.13 KPI36469.1 - 1e-23 84.1 0.0 1.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36469.1 - 1.4e-05 25.1 0.1 4.1e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 KPI36469.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KPI36469.1 - 0.0014 18.6 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPI36469.1 - 0.059 12.4 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GnsAB_toxin PF08178.11 KPI36469.1 - 0.076 13.0 1.5 0.12 12.3 0.2 2.1 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Blt1 PF12754.7 KPI36471.1 - 6.3e-34 117.5 0.5 1.1e-33 116.7 0.5 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KPI36471.1 - 6.6e-09 35.2 0.4 1.5e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 Get5 carboxyl domain Med11 PF10280.9 KPI36472.1 - 3.3e-26 92.4 0.0 4.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein PapD_C PF02753.17 KPI36472.1 - 0.0083 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Pili assembly chaperone PapD, C-terminal domain ptaRNA1_toxin PF12703.7 KPI36472.1 - 0.016 15.2 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system GST_N_3 PF13417.6 KPI36473.1 - 7e-12 45.6 0.1 1.3e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI36473.1 - 2.3e-10 40.6 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI36473.1 - 3.1e-07 30.7 0.0 4.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Striatin PF08232.12 KPI36474.1 - 6.5e-39 134.0 5.8 6.5e-39 134.0 5.8 2.3 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KPI36474.1 - 4.7e-26 90.5 19.5 2e-05 25.2 0.1 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI36474.1 - 1.6e-07 31.5 0.0 0.32 11.3 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI36474.1 - 0.00072 19.5 0.0 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF4482 PF14818.6 KPI36474.1 - 0.01 16.7 3.0 0.01 16.7 3.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4482) Ge1_WD40 PF16529.5 KPI36474.1 - 0.099 11.6 0.0 15 4.4 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KPI36474.1 - 0.18 10.3 0.2 1.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Vps54 PF07928.12 KPI36475.1 - 1.7e-49 167.7 0.2 1.7e-49 167.7 0.2 3.0 3 0 0 3 3 2 1 Vps54-like protein Vps54_N PF10475.9 KPI36475.1 - 1.2e-05 24.8 1.5 1.2e-05 24.8 1.5 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex BLOC1_2 PF10046.9 KPI36475.1 - 0.0056 17.0 0.4 0.031 14.6 0.4 2.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.14 KPI36475.1 - 0.011 15.7 1.4 0.039 13.8 1.4 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FliJ PF02050.16 KPI36475.1 - 0.024 14.8 0.4 0.024 14.8 0.4 2.8 3 0 0 3 3 2 0 Flagellar FliJ protein LUC7 PF03194.15 KPI36475.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 LUC7 N_terminus SurA_N PF09312.11 KPI36475.1 - 0.069 13.2 2.1 0.37 10.9 0.1 2.9 2 0 0 2 2 2 0 SurA N-terminal domain DUF3510 PF12022.8 KPI36475.1 - 0.077 13.4 1.3 1.2 9.5 0.0 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Apolipoprotein PF01442.18 KPI36475.1 - 0.095 12.6 7.0 0.04 13.8 0.4 3.3 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KPI36475.1 - 0.16 9.9 4.0 0.049 11.6 0.8 1.7 2 0 0 2 2 2 0 Prominin Nup54 PF13874.6 KPI36475.1 - 2.7 8.1 11.8 3.4 7.8 2.5 4.2 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 COG2 PF06148.11 KPI36475.1 - 6.8 6.8 7.7 1.5 8.9 3.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Imm49 PF15575.6 KPI36476.1 - 0.048 13.4 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 49 V-ATPase_C PF03223.15 KPI36477.1 - 5.4e-111 371.6 0.0 9.7e-110 367.4 0.0 1.9 1 1 0 1 1 1 1 V-ATPase subunit C HAT_KAT11 PF08214.11 KPI36478.1 - 2.3e-83 280.4 0.0 3e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Deltaretro_Tax PF05599.11 KPI36478.1 - 0.068 13.7 1.3 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Deltaretrovirus Tax protein Exo_endo_phos PF03372.23 KPI36480.1 - 2.4e-09 37.0 0.3 4.4e-09 36.2 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KPI36480.1 - 0.0013 18.6 0.0 0.0042 16.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Nup54 PF13874.6 KPI36481.1 - 3.7e-33 114.6 2.8 3.7e-33 114.6 2.8 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KPI36481.1 - 1.8e-06 27.4 6.2 1.8e-06 27.4 6.2 2.3 3 0 0 3 3 3 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 KPI36481.1 - 0.00018 22.3 25.2 0.00018 22.3 25.2 2.2 1 1 1 2 2 2 2 Nucleoporin FG repeat region Allexi_40kDa PF05549.11 KPI36481.1 - 0.085 12.4 0.2 0.085 12.4 0.2 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF3533 PF12051.8 KPI36481.1 - 0.2 10.5 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FapA PF03961.13 KPI36481.1 - 0.69 8.4 11.0 0.19 10.3 2.3 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 KPI36481.1 - 7.1 6.7 10.0 6.5 6.8 1.2 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DcuA_DcuB PF03605.14 KPI36482.1 - 0.42 9.5 0.6 0.51 9.2 0.6 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PNTB PF02233.16 KPI36483.1 - 5e-155 516.9 49.9 2.2e-88 297.2 3.0 3.0 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KPI36483.1 - 2.5e-64 216.5 2.3 3.4e-64 216.1 0.0 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KPI36483.1 - 2e-45 154.5 0.3 4.8e-45 153.2 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KPI36483.1 - 4.4e-28 97.6 2.4 4.4e-28 97.6 2.4 4.8 3 2 2 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KPI36483.1 - 0.0022 17.4 0.1 0.044 13.2 0.0 2.8 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KPI36483.1 - 0.0052 16.1 0.1 0.014 14.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 KPI36483.1 - 0.0058 16.4 2.2 0.067 12.9 1.4 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KPI36483.1 - 0.035 14.1 0.1 0.25 11.3 0.1 2.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KPI36483.1 - 0.85 9.9 6.6 0.62 10.3 1.6 3.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cep3 PF16846.5 KPI36484.1 - 4.6e-05 22.1 0.1 7.4e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B DEAD PF00270.29 KPI36486.1 - 8.7e-49 165.7 0.0 2.3e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI36486.1 - 9.6e-27 93.5 0.0 3.3e-26 91.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI36486.1 - 0.003 17.6 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1264 PF06884.11 KPI36487.1 - 1.4e-54 184.3 0.2 1.7e-54 184.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) MCM PF00493.23 KPI36488.1 - 1.9e-103 344.4 0.1 4.4e-103 343.2 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KPI36488.1 - 1e-35 122.3 0.2 2.1e-35 121.3 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPI36488.1 - 1.4e-27 96.0 1.1 3.1e-27 94.8 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPI36488.1 - 2.1e-14 53.9 0.2 4.8e-14 52.8 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPI36488.1 - 2.5e-06 27.0 0.0 0.00021 20.8 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPI36488.1 - 4.7e-05 23.4 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KPI36488.1 - 0.00059 19.7 0.1 0.0022 17.8 0.1 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPI36488.1 - 0.042 13.6 0.0 0.98 9.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain HA70_C PF17993.1 KPI36488.1 - 0.049 13.7 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Haemagglutinin 70 C-terminal domain BTB PF00651.31 KPI36489.1 - 5.1e-06 26.7 0.0 1.5e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 KPI36490.1 - 8.7e-43 146.6 0.0 5.5e-41 140.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36490.1 - 1e-25 90.5 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI36490.1 - 0.00067 18.5 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KPI36490.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPI36490.1 - 0.077 12.3 0.1 0.43 9.9 0.1 1.8 1 1 0 1 1 1 0 Kinase-like DUF2237 PF09996.9 KPI36491.1 - 5.8e-41 139.1 0.0 7.3e-41 138.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF2841 PF11001.8 KPI36492.1 - 0.044 13.8 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) Glutaredoxin PF00462.24 KPI36493.1 - 1.5e-20 73.2 0.0 3.3e-17 62.4 0.0 3.1 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 KPI36493.1 - 1.6e-13 50.5 0.0 7.9e-13 48.3 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin MAP2_projctn PF08377.10 KPI36493.1 - 0.0055 14.8 0.3 0.0068 14.5 0.3 1.1 1 0 0 1 1 1 1 MAP2/Tau projection domain Thioredoxin_8 PF13905.6 KPI36493.1 - 0.008 16.5 0.0 0.17 12.2 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like IMPa_N_2 PF18650.1 KPI36493.1 - 0.15 11.3 0.0 2.6 7.2 0.0 2.3 2 1 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain OST3_OST6 PF04756.13 KPI36493.1 - 0.24 10.7 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Bac_luciferase PF00296.20 KPI36494.1 - 2.2e-62 211.3 0.1 2.8e-62 210.9 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_transf_25 PF01755.17 KPI36495.1 - 2e-05 24.5 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Abhydrolase_1 PF00561.20 KPI36496.1 - 5.5e-14 52.4 0.2 8.9e-14 51.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI36496.1 - 4.7e-10 40.5 2.7 6.5e-10 40.0 2.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KPI36496.1 - 0.13 12.6 1.6 0.71 10.3 0.1 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Hydrolase_4 PF12146.8 KPI36496.1 - 0.2 10.9 0.1 1.2 8.3 0.1 2.0 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KPI36497.1 - 5.7e-41 140.9 0.2 8.2e-41 140.4 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KPI36497.1 - 4.7e-34 118.3 0.0 7e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KPI36497.1 - 0.0018 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Dynamin_N PF00350.23 KPI36498.1 - 9.9e-24 84.3 0.0 4.4e-23 82.2 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPI36498.1 - 7.1e-21 74.7 0.0 2e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 KPI36498.1 - 9.2e-05 22.5 0.8 0.00042 20.4 0.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KPI36498.1 - 0.0001 22.4 0.1 0.0035 17.4 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KPI36498.1 - 0.033 13.9 0.8 0.71 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 KPI36498.1 - 0.035 13.6 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 KPI36498.1 - 0.17 12.3 1.4 3.3 8.2 0.0 3.0 3 1 0 3 3 3 0 AAA domain adh_short PF00106.25 KPI36499.1 - 1.2e-29 103.2 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36499.1 - 1.1e-14 54.6 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36499.1 - 8.3e-05 22.6 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KPI36499.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KPI36499.1 - 0.052 13.2 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF3437 PF11919.8 KPI36499.1 - 0.053 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) ThrE_2 PF12821.7 KPI36499.1 - 0.079 13.1 0.6 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE NAD_binding_10 PF13460.6 KPI36499.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Pex19 PF04614.12 KPI36500.1 - 2.7e-62 210.7 11.1 2.7e-62 210.7 11.1 1.7 2 0 0 2 2 2 1 Pex19 protein family GET2 PF08690.10 KPI36500.1 - 0.0016 18.2 10.0 0.0016 18.2 10.0 2.4 2 1 0 2 2 2 1 GET complex subunit GET2 SPX PF03105.19 KPI36500.1 - 0.52 10.2 20.4 1.1 9.1 7.8 2.1 2 0 0 2 2 2 0 SPX domain Integrase_H2C2 PF17921.1 KPI36501.1 - 1.7e-07 31.3 0.4 1.7e-07 31.3 0.4 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain MARVEL PF01284.23 KPI36502.1 - 4.4e-05 23.5 11.5 9.4e-05 22.5 11.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Pkinase PF00069.25 KPI36504.1 - 1.7e-49 168.6 0.0 6.3e-33 114.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36504.1 - 6.5e-22 78.1 0.0 2.6e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI36504.1 - 0.00027 19.8 1.9 0.0005 19.0 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KPI36504.1 - 0.00049 20.1 0.3 0.0016 18.4 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI36504.1 - 0.002 17.5 0.0 0.012 15.0 0.0 2.0 1 1 0 1 1 1 1 Kinase-like DUF2420 PF10336.9 KPI36505.1 - 8.8e-12 45.0 0.0 2.8e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Fungal_trans PF04082.18 KPI36506.1 - 2.1e-20 72.9 0.3 5.7e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 KPI36507.1 - 2.2e-12 46.6 0.4 3.5e-12 45.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI36507.1 - 6.6e-06 26.1 11.5 1.2e-05 25.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG22 PF11700.8 KPI36508.1 - 1.2e-46 159.4 30.2 3.2e-46 158.0 30.2 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like eIF-3c_N PF05470.12 KPI36509.1 - 1.9e-154 515.3 29.0 1.9e-154 515.3 29.0 4.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KPI36509.1 - 2.2e-13 50.6 0.4 1.2e-12 48.2 0.0 2.5 2 0 0 2 2 2 1 PCI domain BORCS7 PF16088.5 KPI36509.1 - 0.0075 16.5 3.4 0.025 14.9 1.5 2.5 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 7 DUF1385 PF07136.11 KPI36509.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF883 PF05957.13 KPI36509.1 - 0.17 12.5 2.1 13 6.5 0.9 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF16 PF01519.16 KPI36509.1 - 2.9 8.4 8.7 3.3 8.3 0.2 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KPI36509.1 - 3.4 7.9 8.9 1.2 9.4 2.7 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Transp_cyt_pur PF02133.15 KPI36510.1 - 4.9e-20 71.7 40.3 6.6e-20 71.3 40.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.8 KPI36510.1 - 4.6 7.2 14.6 0.29 11.0 8.6 2.0 2 0 0 2 2 2 0 Conserved membrane protein YqhR GMC_oxred_N PF00732.19 KPI36511.1 - 8.1e-77 258.5 0.0 1.1e-76 258.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI36511.1 - 2.9e-33 115.4 0.3 2.1e-32 112.6 0.3 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI36511.1 - 2.5e-05 23.6 0.0 0.023 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KPI36511.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KPI36511.1 - 0.076 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KPI36511.1 - 0.15 11.3 0.0 0.39 9.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI36511.1 - 0.19 11.3 0.6 0.96 9.0 0.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase EAP30 PF04157.16 KPI36512.1 - 5.4e-67 225.5 0.0 6.2e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Glt_symporter PF03616.14 KPI36512.1 - 0.042 12.5 0.3 0.062 12.0 0.3 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter LigB PF02900.18 KPI36513.1 - 1.8e-11 43.7 0.0 2.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PH_8 PF15409.6 KPI36513.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain TauD PF02668.16 KPI36514.1 - 1e-40 140.2 0.7 1.4e-40 139.8 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KPI36514.1 - 0.034 13.3 0.0 0.067 12.3 0.0 1.4 2 0 0 2 2 2 0 CsiD Molybdopterin PF00384.22 KPI36515.1 - 7.6e-33 114.1 0.0 1.3e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase DUF2985 PF11204.8 KPI36515.1 - 4.6e-21 74.8 2.3 8.7e-21 73.9 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) NADH-G_4Fe-4S_3 PF10588.9 KPI36515.1 - 5.1e-17 61.1 0.2 1.2e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 KPI36515.1 - 1.4e-07 31.4 0.1 4e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Molybdopterin PF00384.22 KPI36516.1 - 1.8e-34 119.5 0.0 2.6e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 KPI36516.1 - 1.3e-17 64.2 0.0 2.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Ima1_N PF09779.9 KPI36517.1 - 4.3e-27 95.6 7.2 7.5e-27 94.8 7.2 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.11 KPI36517.1 - 0.0027 17.6 2.5 0.0027 17.6 2.5 2.2 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf-RRPl_C4 PF17026.5 KPI36517.1 - 2.5 8.3 5.3 6 7.0 5.3 1.6 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type PriA_CRR PF18319.1 KPI36517.1 - 2.9 8.0 10.1 0.11 12.5 3.5 2.1 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain UPF0061 PF02696.14 KPI36518.1 - 3.2e-51 174.6 0.0 3.9e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF4391 PF14335.6 KPI36518.1 - 0.011 15.4 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) CR6_interact PF10147.9 KPI36518.1 - 0.091 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 WD-3 PF09765.9 KPI36518.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 WD-repeat region SLAC1 PF03595.17 KPI36519.1 - 1.3e-54 185.7 43.6 1.5e-54 185.5 43.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2852 PF11014.8 KPI36519.1 - 0.22 11.7 6.4 0.3 11.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Aldedh PF00171.22 KPI36520.1 - 5.5e-154 513.1 1.3 6.2e-154 512.9 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPI36520.1 - 0.025 13.6 0.2 0.17 10.9 0.2 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pkinase PF00069.25 KPI36521.1 - 5.5e-28 98.1 0.0 6.4e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36521.1 - 1e-14 54.5 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI36521.1 - 1.9e-07 30.2 0.0 2.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase A_deaminase PF00962.22 KPI36522.1 - 4.1e-51 174.2 0.0 4.8e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase FAD_binding_3 PF01494.19 KPI36523.1 - 5.4e-16 58.8 0.2 8.4e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI36523.1 - 1.2e-05 25.0 1.3 0.031 13.8 1.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI36523.1 - 0.00087 19.5 0.5 0.0022 18.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI36523.1 - 0.0029 16.9 0.1 0.0083 15.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KPI36523.1 - 0.0069 16.3 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain SE PF08491.10 KPI36523.1 - 0.18 10.8 0.0 0.45 9.5 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase AAA PF00004.29 KPI36524.1 - 2.6e-14 53.8 0.8 2.6e-12 47.3 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KPI36524.1 - 1.3e-13 51.4 0.0 2.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 KPI36524.1 - 5.7e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI36524.1 - 6.1e-05 23.5 0.1 0.00011 22.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KPI36524.1 - 0.00031 20.7 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KPI36524.1 - 0.0015 19.1 0.0 0.003 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPI36524.1 - 0.0025 18.0 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KPI36524.1 - 0.004 17.4 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI36524.1 - 0.032 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KPI36524.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPI36524.1 - 0.042 13.6 0.1 0.33 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KPI36524.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KPI36524.1 - 0.062 13.6 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain IstB_IS21 PF01695.17 KPI36524.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KPI36524.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KPI36524.1 - 0.093 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KPI36524.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KPI36524.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain GST_N_2 PF13409.6 KPI36525.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI36525.1 - 0.00058 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI36525.1 - 0.00086 19.3 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KPI36525.1 - 0.0057 16.4 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI36525.1 - 0.0064 16.8 0.1 0.024 15.0 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FAD_binding_3 PF01494.19 KPI36526.1 - 1.3e-17 64.2 0.2 8.1e-08 31.9 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI36526.1 - 0.0016 18.6 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI36526.1 - 0.0077 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI36526.1 - 0.0091 15.6 0.3 0.024 14.2 0.1 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KPI36526.1 - 0.023 13.7 0.0 0.068 12.2 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 KPI36526.1 - 0.06 13.3 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI36526.1 - 0.13 11.3 0.0 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Mid2 PF04478.12 KPI36527.1 - 0.025 14.4 3.8 0.025 14.4 3.8 2.4 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor Hamartin PF04388.12 KPI36527.1 - 0.7 8.5 13.2 0.89 8.1 13.2 1.1 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 KPI36527.1 - 2.6 7.9 7.5 3.5 7.5 7.5 1.2 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 KPI36527.1 - 5.6 5.8 15.5 6.6 5.6 15.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal FAD_binding_3 PF01494.19 KPI36528.1 - 1.3e-19 70.7 0.0 2.1e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 KPI36528.1 - 1.8e-17 63.7 0.0 3.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 KPI36528.1 - 1.2e-06 28.6 0.3 3.9e-06 27.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI36528.1 - 7.6e-06 25.4 0.2 0.0052 16.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI36528.1 - 0.00013 21.2 2.1 0.00016 20.9 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KPI36528.1 - 0.0002 20.4 0.8 0.051 12.4 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KPI36528.1 - 0.0012 18.0 0.1 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPI36528.1 - 0.0035 16.1 0.2 0.0067 15.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KPI36528.1 - 0.025 14.0 0.7 0.065 12.6 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KPI36528.1 - 0.078 12.5 3.2 0.34 10.4 1.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI36528.1 - 0.1 13.2 0.3 0.24 12.0 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 KPI36529.1 - 6e-07 28.6 0.0 1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 KPI36530.1 - 4.7e-113 377.9 0.0 5.3e-113 377.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.25 KPI36531.1 - 3.4e-34 118.0 0.1 4.8e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36531.1 - 4.4e-34 118.0 4.3 6.3e-33 114.3 4.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36531.1 - 7.2e-09 35.8 0.1 2.3e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPI36531.1 - 0.014 14.9 0.2 0.64 9.4 0.0 2.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family ATPase PF06745.13 KPI36531.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC UDPG_MGDP_dh_C PF03720.15 KPI36531.1 - 0.09 13.2 0.0 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Actin PF00022.19 KPI36532.1 - 1.4e-25 89.8 0.0 1.4e-17 63.4 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KPI36532.1 - 7.8e-06 24.9 0.5 1.4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KPI36532.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Cell division protein FtsA Actin_micro PF17003.5 KPI36532.1 - 0.045 12.9 0.0 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 Putative actin-like family DUF2114 PF09887.9 KPI36532.1 - 0.11 10.9 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) UL17 PF17640.2 KPI36532.1 - 1.1 9.3 4.2 7.8 6.6 1.0 2.8 2 0 0 2 2 2 0 Uncharacterized UL17 Ribosomal_S19e PF01090.19 KPI36533.1 - 7.3e-57 190.9 0.1 8.4e-57 190.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e LAGLIDADG_3 PF14528.6 KPI36533.1 - 0.034 14.4 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG-like domain MFS_1 PF07690.16 KPI36534.1 - 4.4e-37 127.8 28.4 7.2e-36 123.8 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36534.1 - 6.8e-11 41.7 9.5 6.8e-11 41.7 9.5 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI36534.1 - 2.9e-08 32.6 4.8 4.7e-08 31.9 4.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KPI36535.1 - 7.5e-67 226.1 0.0 8.4e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDP-OH_P_transf PF01066.21 KPI36536.1 - 1.7e-14 54.3 0.2 1.7e-14 54.3 0.2 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_zinc_N PF00107.26 KPI36537.1 - 2.1e-19 69.8 0.2 9.3e-19 67.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI36537.1 - 3.5e-16 59.0 1.4 6.7e-16 58.1 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI36537.1 - 0.0047 18.0 0.0 0.0084 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 KPI36538.1 - 2.6e-34 118.8 0.0 6.9e-19 68.2 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36538.1 - 1.9e-12 47.0 0.0 5e-06 26.0 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KPI36538.1 - 1.9e-05 24.7 0.2 4.9e-05 23.4 0.2 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family eIF3_subunit PF08597.10 KPI36538.1 - 0.35 10.8 3.8 0.54 10.1 3.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ADH_zinc_N PF00107.26 KPI36539.1 - 2.1e-09 37.4 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KPI36540.1 - 1.2e-09 37.6 0.0 2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.26 KPI36541.1 - 2.1e-12 46.8 0.1 3.8e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 KPI36542.1 - 4.8e-13 49.4 6.7 0.18 12.7 0.2 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI36542.1 - 0.006 16.9 0.1 3.4 8.0 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KPI36545.1 - 2.6e-57 194.6 0.0 3.2e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KPI36546.1 - 6.5e-31 107.5 54.8 1.2e-30 106.7 49.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36546.1 - 0.00023 20.2 14.0 0.00023 20.2 14.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TraQ PF09679.10 KPI36546.1 - 0.053 13.4 0.6 0.6 10.1 0.0 2.6 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Papilloma_E5A PF05776.12 KPI36546.1 - 6.5 7.2 8.4 1.9 8.9 1.7 2.7 2 0 0 2 2 2 0 Papillomavirus E5A protein Sugar_tr PF00083.24 KPI36547.1 - 2.6e-32 112.3 17.8 3e-32 112.1 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36547.1 - 7.6e-09 34.9 7.7 8.3e-09 34.8 7.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DNA_pol_B PF00136.21 KPI36548.1 - 3.3e-118 395.3 2.5 4.9e-118 394.8 2.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KPI36548.1 - 8.3e-66 221.3 6.2 1.7e-65 220.2 6.2 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KPI36548.1 - 4.2e-37 128.0 0.0 7.5e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KPI36548.1 - 9.6e-26 89.7 9.4 2.6e-25 88.3 5.1 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KPI36548.1 - 0.0043 16.0 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Fasciclin PF02469.22 KPI36549.1 - 4.8e-32 110.9 1.9 5.8e-17 62.1 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain UPF0061 PF02696.14 KPI36550.1 - 2.8e-58 197.8 0.0 3.6e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF1127 PF06568.11 KPI36550.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) PEARLI-4 PF05278.12 KPI36551.1 - 0.014 15.0 9.4 0.57 9.7 0.7 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Laminin_II PF06009.12 KPI36551.1 - 0.04 13.9 1.2 2 8.4 0.0 2.3 1 1 1 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 KPI36551.1 - 0.052 13.6 7.8 0.14 12.1 7.6 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 KPI36551.1 - 0.068 13.3 1.7 0.43 10.7 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 KPI36551.1 - 0.081 13.6 3.1 0.83 10.3 1.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 KPI36551.1 - 0.12 13.0 9.8 1.1 9.8 9.8 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 KPI36551.1 - 0.15 12.5 3.9 0.28 11.7 0.8 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TSNAXIP1_N PF15739.5 KPI36551.1 - 0.15 12.4 4.8 0.7 10.3 4.8 2.1 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus NYD-SP28_assoc PF14775.6 KPI36551.1 - 0.2 11.8 0.2 0.2 11.8 0.2 1.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF2524 PF10732.9 KPI36551.1 - 0.2 12.0 3.8 0.31 11.4 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) NRBF2 PF08961.10 KPI36551.1 - 0.26 10.9 6.3 0.58 9.7 6.3 1.6 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Sin3_corepress PF08295.12 KPI36551.1 - 0.41 10.7 4.1 4.2 7.5 0.3 2.8 1 1 2 3 3 3 0 Sin3 family co-repressor Fungal_trans_2 PF11951.8 KPI36552.1 - 4.5e-13 48.8 0.6 7.6e-12 44.7 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.13 KPI36553.1 - 2.4e-190 632.7 0.2 2.8e-190 632.5 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ApbA PF02558.16 KPI36554.1 - 1.5e-26 92.8 0.1 2.1e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KPI36554.1 - 3.8e-24 85.3 0.0 6.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal UDPG_MGDP_dh_N PF03721.14 KPI36554.1 - 0.042 13.4 0.3 0.07 12.7 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GLEYA PF10528.9 KPI36555.1 - 9.2e-18 64.5 0.0 4.1e-17 62.4 0.0 2.2 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KPI36555.1 - 0.00016 21.5 0.0 0.00065 19.5 0.0 2.1 2 0 0 2 2 2 1 PA14 domain Pkinase PF00069.25 KPI36556.1 - 1.2e-50 172.3 0.1 5.8e-50 170.1 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36556.1 - 1.4e-23 83.5 0.1 3.6e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KPI36556.1 - 7.3e-06 26.1 8.4 0.00045 20.2 0.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KPI36556.1 - 0.0024 17.5 0.2 0.0091 15.6 0.2 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KPI36556.1 - 0.28 10.7 1.4 0.34 10.4 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase MLANA PF14991.6 KPI36556.1 - 0.76 10.1 6.7 2.1 8.6 6.7 1.8 1 0 0 1 1 1 0 Protein melan-A FMO-like PF00743.19 KPI36558.1 - 6.5e-16 57.8 0.0 2.3e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI36558.1 - 9.8e-12 44.7 0.0 5.1e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI36558.1 - 6.2e-11 42.1 0.0 6.8e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI36558.1 - 1.2e-07 31.8 0.0 3.8e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI36558.1 - 4.1e-06 26.2 0.0 0.00024 20.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI36558.1 - 3.6e-05 23.8 0.2 0.012 15.6 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPI36558.1 - 0.00087 18.6 0.1 0.0064 15.8 0.0 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KPI36558.1 - 0.033 14.7 0.2 0.26 11.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI36558.1 - 0.17 10.6 0.1 0.97 8.1 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KPI36558.1 - 0.17 11.2 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KPI36558.1 - 0.2 11.2 3.0 0.37 10.3 0.5 2.6 2 2 2 4 4 4 0 FAD dependent oxidoreductase BCAS2 PF05700.11 KPI36559.1 - 5.3e-58 196.1 5.5 6.4e-58 195.8 5.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Csm1_N PF18504.1 KPI36559.1 - 0.13 12.7 0.5 0.13 12.7 0.5 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain Spore_III_AB PF09548.10 KPI36559.1 - 0.13 12.3 2.5 0.2 11.7 1.9 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LprI PF07007.12 KPI36559.1 - 4.4 8.0 10.5 16 6.2 2.3 2.7 1 1 1 2 2 2 0 Lysozyme inhibitor LprI NAD_binding_8 PF13450.6 KPI36560.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI36560.1 - 0.0008 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KPI36560.1 - 0.0019 17.6 0.2 0.0032 16.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KPI36560.1 - 0.0021 17.7 0.8 0.0035 17.0 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI36560.1 - 0.0065 15.6 0.2 0.015 14.4 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI36560.1 - 0.02 13.6 0.1 0.035 12.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KPI36560.1 - 0.02 14.1 0.1 0.055 12.7 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI36560.1 - 0.088 12.0 0.3 0.18 11.0 0.3 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KPI36560.1 - 0.22 10.7 0.5 0.38 10.0 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Formyl_trans_N PF00551.19 KPI36561.1 - 3.2e-25 88.9 0.0 4.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase FAD_binding_3 PF01494.19 KPI36562.1 - 2.7e-17 63.1 0.2 9.9e-17 61.2 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI36562.1 - 8.8e-06 25.5 0.4 0.0011 18.6 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI36562.1 - 2.6e-05 24.3 0.1 6.7e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI36562.1 - 0.00021 20.5 0.1 0.0006 19.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KPI36562.1 - 0.0003 20.1 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KPI36562.1 - 0.00075 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI36562.1 - 0.0038 16.5 0.1 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI36562.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KPI36562.1 - 0.12 13.0 0.0 0.43 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPI36562.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KPI36562.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI36562.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) KOW PF00467.29 KPI36564.1 - 0.00018 21.3 3.9 0.00018 21.3 3.9 2.1 2 0 0 2 2 2 1 KOW motif Collagen PF01391.18 KPI36566.1 - 0.0073 16.0 4.9 0.016 14.9 4.9 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ribosomal_L30_N PF08079.12 KPI36567.1 - 2.1e-26 92.0 17.3 2.1e-26 92.0 17.3 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KPI36567.1 - 4.7e-18 64.8 1.9 4.7e-18 64.8 1.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Aminotran_3 PF00202.21 KPI36568.1 - 1.2e-10 40.7 0.0 1.2e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short_C2 PF13561.6 KPI36569.1 - 5.7e-49 166.8 3.1 1.4e-47 162.3 3.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36569.1 - 4.8e-38 130.6 4.5 6.3e-37 126.9 4.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36569.1 - 4.4e-08 33.2 0.7 7.1e-08 32.6 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI36569.1 - 0.00014 21.4 0.1 0.00016 21.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KPI36569.1 - 0.0014 18.5 0.3 0.002 18.0 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KPI36569.1 - 0.12 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cupin_2 PF07883.11 KPI36570.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPI36570.1 - 0.0085 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MFS_1 PF07690.16 KPI36571.1 - 2.3e-31 109.0 40.3 6e-29 101.1 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RSN1_7TM PF02714.15 KPI36572.1 - 4.6e-62 209.8 24.8 4.6e-62 209.8 24.8 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPI36572.1 - 4.7e-39 133.7 1.2 4.7e-39 133.7 1.2 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPI36572.1 - 2.7e-16 60.3 0.1 1.2e-15 58.2 0.1 2.0 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPI36572.1 - 1.2e-15 57.5 0.0 2.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF2231 PF09990.9 KPI36572.1 - 1.9 8.9 7.0 3.3 8.2 0.2 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) PsbI PF02532.14 KPI36572.1 - 5.2 7.1 7.5 20 5.2 7.5 2.1 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF3861 PF12977.7 KPI36573.1 - 0.0039 17.3 0.4 0.0056 16.8 0.4 1.6 1 1 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3861) Saccharop_dh_N PF04455.12 KPI36573.1 - 0.05 14.0 0.1 0.066 13.6 0.1 1.3 1 1 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Alpha-amylase PF00128.24 KPI36574.1 - 1.3e-111 373.4 0.1 1.3e-111 373.4 0.1 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KPI36574.1 - 2e-08 34.2 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KPI36574.1 - 1.7e-05 24.2 0.0 3.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 KPI36574.1 - 0.00058 20.3 0.0 0.0031 17.9 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_42C PF08533.10 KPI36574.1 - 0.0038 16.9 0.8 0.023 14.4 0.0 2.8 4 0 0 4 4 4 1 Beta-galactosidase C-terminal domain MFS_1 PF07690.16 KPI36576.1 - 2.7e-32 112.1 37.6 2.7e-32 112.1 37.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI36578.1 - 1.2e-59 202.4 23.3 1.4e-59 202.1 23.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI36578.1 - 4.3e-20 72.0 53.2 9.4e-19 67.5 52.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MmgE_PrpD PF03972.14 KPI36579.1 - 1.4e-113 379.8 4.6 1.6e-113 379.6 4.6 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.16 KPI36580.1 - 1.2e-32 113.2 47.7 1.2e-32 113.2 47.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36580.1 - 5e-09 35.5 14.3 5e-09 35.5 14.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPI36580.1 - 2.3e-06 26.3 17.3 3.6e-06 25.7 17.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KPI36580.1 - 0.00053 18.4 1.5 0.00053 18.4 1.5 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF1700 PF08006.11 KPI36580.1 - 0.18 11.3 6.2 0.027 14.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DotU PF09850.9 KPI36581.1 - 0.16 11.7 0.2 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF3047 PF11249.8 KPI36582.1 - 1.9e-26 92.6 0.2 2.6e-26 92.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3047) SNF2_N PF00176.23 KPI36583.1 - 6.6e-63 212.5 0.0 1.4e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI36583.1 - 3.1e-18 66.1 0.0 1.5e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI36583.1 - 6e-07 29.6 0.0 2.4e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 KPI36583.1 - 0.00012 22.1 0.0 0.00038 20.5 0.0 1.9 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain ERCC3_RAD25_C PF16203.5 KPI36583.1 - 0.086 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HK97-gp10_like PF04883.12 KPI36583.1 - 0.74 10.8 3.9 6.7 7.8 0.1 3.6 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component CASP_C PF08172.12 KPI36583.1 - 5 6.4 7.6 11 5.3 7.6 1.5 1 0 0 1 1 1 0 CASP C terminal FapA PF03961.13 KPI36583.1 - 6.7 5.2 8.2 1.2 7.7 2.5 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A HpcH_HpaI PF03328.14 KPI36585.1 - 4.6e-43 146.9 0.0 6.2e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KPI36585.1 - 5.2e-12 45.6 0.2 1.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold NAD_binding_10 PF13460.6 KPI36586.1 - 2.7e-12 47.0 0.0 2.7e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI36586.1 - 9.1e-07 28.7 0.1 3.4e-06 26.8 0.0 2.0 2 1 0 2 2 2 1 NmrA-like family PAC2 PF09754.9 KPI36586.1 - 0.14 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 PAC2 family Fungal_trans PF04082.18 KPI36587.1 - 1.6e-20 73.3 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HOASN PF14515.6 KPI36587.1 - 0.12 12.8 0.1 0.8 10.1 0.0 2.3 2 1 1 3 3 3 0 Haem-oxygenase-associated N-terminal helices Acetyltransf_3 PF13302.7 KPI36588.1 - 1.7e-06 28.7 0.0 2.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_23 PF13489.6 KPI36589.1 - 5.6e-24 84.8 0.0 8.5e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI36589.1 - 2.1e-14 54.0 0.0 6.2e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI36589.1 - 2.1e-11 44.3 0.0 5.9e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI36589.1 - 8.4e-09 36.1 0.0 2.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI36589.1 - 9e-08 32.1 0.0 1.1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI36589.1 - 0.0019 17.6 0.0 0.018 14.4 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPI36589.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KPI36589.1 - 0.0052 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPI36589.1 - 0.0098 15.4 0.0 0.03 13.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KPI36589.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KPI36589.1 - 0.024 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KPI36589.1 - 0.034 13.9 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KPI36589.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3889 PF13028.6 KPI36589.1 - 0.18 11.8 0.0 0.49 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) p450 PF00067.22 KPI36590.1 - 1.6e-61 208.5 0.0 3.2e-61 207.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 FAA_hydrolase PF01557.18 KPI36590.1 - 1.7e-51 175.0 0.0 2.7e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPI36590.1 - 1.2e-27 96.2 0.0 2.5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal zf-MYND PF01753.18 KPI36591.1 - 4.9e-12 45.7 12.4 4.9e-12 45.7 12.4 1.9 2 0 0 2 2 2 1 MYND finger Yeast_MT PF11403.8 KPI36591.1 - 0.023 15.3 5.7 0.072 13.7 5.7 1.8 1 0 0 1 1 1 0 Yeast metallothionein Glyco_hydro_42M PF08532.10 KPI36591.1 - 0.032 13.7 0.1 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 Beta-galactosidase trimerisation domain zf-C6H2 PF15801.5 KPI36591.1 - 0.052 13.9 8.4 0.16 12.3 8.4 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C2H2 PF00096.26 KPI36592.1 - 2.2e-13 49.9 10.4 3.3e-06 27.2 2.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI36592.1 - 3.4e-12 46.2 10.4 1.7e-07 31.3 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI36592.1 - 1.3e-08 35.0 10.6 0.00077 20.1 1.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPI36592.1 - 1.9e-07 30.9 6.0 0.0019 18.2 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI36592.1 - 5.3e-06 26.6 2.5 0.057 13.7 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI36592.1 - 3.1e-05 24.2 1.2 0.011 16.1 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KPI36592.1 - 0.00041 20.0 3.7 0.08 12.7 0.6 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KPI36592.1 - 0.072 13.4 1.7 0.14 12.5 1.7 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KPI36592.1 - 0.24 11.9 0.8 0.55 10.8 0.8 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KPI36592.1 - 0.66 10.5 3.0 14 6.2 0.6 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KPI36592.1 - 0.69 10.2 3.3 13 6.1 0.2 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 KPI36592.1 - 2.1 8.6 6.0 21 5.4 1.3 2.7 1 1 1 2 2 2 0 NSD Cys-His rich domain Ntox30 PF15532.6 KPI36593.1 - 0.094 13.1 0.3 0.18 12.2 0.3 1.8 1 1 0 1 1 1 0 Bacterial toxin 30 Phos_pyr_kin PF08543.12 KPI36594.1 - 9.5e-50 169.3 0.0 1.8e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KPI36594.1 - 8e-44 150.0 0.3 1.2e-43 149.4 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family zf-C2H2 PF00096.26 KPI36596.1 - 7e-14 51.4 16.7 1e-05 25.7 1.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI36596.1 - 5.5e-07 29.9 20.2 0.068 14.0 0.5 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPI36596.1 - 5.2e-05 23.1 18.8 0.23 11.5 1.4 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger Peptidase_M1_N PF17900.1 KPI36596.1 - 0.00039 20.7 0.1 0.066 13.4 0.1 2.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain zf-C2H2_11 PF16622.5 KPI36596.1 - 0.00042 20.0 14.3 0.012 15.4 0.2 4.3 4 0 0 4 4 4 2 zinc-finger C2H2-type Peptidase_M1 PF01433.20 KPI36596.1 - 0.00089 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain zf-met PF12874.7 KPI36596.1 - 0.019 15.3 7.5 5.9 7.4 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 KPI36596.1 - 0.082 13.4 15.9 1.4 9.5 0.2 4.2 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain LapD_MoxY_N PF16448.5 KPI36596.1 - 0.13 12.1 0.4 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain zf-C2H2_3rep PF18868.1 KPI36596.1 - 0.25 12.0 3.3 8.9 7.0 0.6 3.1 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn_ribbon_SprT PF17283.2 KPI36596.1 - 0.45 10.5 14.3 0.11 12.4 2.4 2.9 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_2 PF13465.6 KPI36596.1 - 0.59 10.7 23.9 6.1 7.4 1.5 5.3 5 0 0 5 5 5 0 Zinc-finger double domain zf-trcl PF13451.6 KPI36596.1 - 2.7 8.0 13.9 0.58 10.1 2.4 3.2 2 1 0 2 2 2 0 Probable zinc-ribbon domain Elf1 PF05129.13 KPI36596.1 - 8.9 6.4 9.9 1.5 8.9 1.1 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like LSM PF01423.22 KPI36598.1 - 2.1e-20 72.1 0.2 2.4e-20 72.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain Sugar_tr PF00083.24 KPI36599.1 - 8.2e-101 338.1 28.9 9.3e-101 337.9 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36599.1 - 1.7e-24 86.4 64.3 4.5e-23 81.7 34.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 KPI36599.1 - 2.2 7.9 5.8 1.1 8.9 2.9 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aldedh PF00171.22 KPI36600.1 - 8.7e-06 24.5 0.0 0.031 12.8 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Glyco_transf_34 PF05637.12 KPI36601.1 - 3.1e-12 46.7 0.0 4.3e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family ER_lumen_recept PF00810.18 KPI36602.1 - 3.1e-50 170.8 3.8 5e-50 170.2 3.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KPI36602.1 - 0.025 14.3 0.6 4.8 7.0 0.3 2.7 2 0 0 2 2 2 0 PQ loop repeat AA_permease_2 PF13520.6 KPI36603.1 - 4.5e-51 174.0 55.1 5.5e-51 173.7 55.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI36603.1 - 2.8e-15 55.9 43.8 3.7e-15 55.5 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_1 PF00190.22 KPI36604.1 - 4.7e-24 84.7 0.2 3.5e-14 52.7 0.1 2.4 2 1 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPI36604.1 - 8.5e-08 31.8 0.4 0.017 14.8 0.0 2.7 2 1 0 2 2 2 2 Cupin domain NmrA PF05368.13 KPI36605.1 - 1.5e-15 57.4 0.1 2e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36605.1 - 8.6e-10 38.8 0.9 2.2e-09 37.5 0.3 1.9 1 1 1 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPI36605.1 - 0.0079 15.4 0.2 0.029 13.6 0.0 2.0 3 0 0 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.19 KPI36605.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KPI36605.1 - 0.015 15.7 0.6 0.066 13.7 0.2 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KPI36605.1 - 0.026 14.4 0.1 0.068 13.1 0.1 1.7 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 KPI36605.1 - 0.076 12.5 0.3 0.27 10.7 0.1 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Alg14 PF08660.11 KPI36606.1 - 3.3e-45 154.1 0.0 1e-44 152.5 0.0 1.8 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_trans_4_4 PF13579.6 KPI36606.1 - 0.046 14.2 0.0 0.11 12.9 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain zf_CCCH_4 PF18345.1 KPI36607.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.7 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH PF00642.24 KPI36607.1 - 3.6 7.6 6.6 2.5 8.1 0.1 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MR_MLE_C PF13378.6 KPI36608.1 - 9.6e-53 179.0 0.1 1.5e-52 178.4 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI36608.1 - 4.7e-23 81.6 0.1 2.1e-21 76.3 0.0 2.7 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF3903 PF13043.6 KPI36608.1 - 0.22 11.3 0.6 0.53 10.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) Kelch_5 PF13854.6 KPI36609.1 - 5.2e-20 71.0 7.4 2.5e-08 33.7 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KPI36609.1 - 6.6e-09 35.7 14.9 0.093 13.1 0.4 6.0 4 1 1 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KPI36609.1 - 9.2e-09 35.4 9.6 0.00018 21.7 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KPI36609.1 - 5.4e-08 32.7 8.7 0.012 15.6 0.1 4.7 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KPI36609.1 - 1e-06 28.2 8.2 0.018 14.6 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KPI36609.1 - 2.1e-06 27.5 5.5 0.012 15.6 0.2 4.7 5 0 0 5 5 5 2 Kelch motif SKG6 PF08693.10 KPI36609.1 - 0.015 14.7 0.5 0.032 13.6 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain XRN_M PF17846.1 KPI36610.1 - 1.8e-99 333.7 6.0 3.8e-99 332.6 6.0 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KPI36610.1 - 3e-96 321.5 0.5 5.1e-96 320.8 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KPI36610.1 - 3e-61 206.6 0.2 3e-61 206.6 0.2 1.8 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KPI36610.1 - 3.7e-31 107.2 0.0 1.9e-30 104.9 0.0 2.3 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KPI36610.1 - 1.4e-22 79.6 0.3 2.8e-22 78.6 0.3 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KPI36610.1 - 1.9e-07 31.0 0.1 4.4e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 R3H PF01424.22 KPI36610.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 R3H domain Peptidase_C92 PF05708.12 KPI36610.1 - 0.32 11.1 2.0 0.31 11.1 0.3 1.8 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Thioredox_DsbH PF03190.15 KPI36611.1 - 2.6e-66 222.6 0.0 7e-66 221.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KPI36611.1 - 1.9e-06 27.9 0.0 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 KPI36611.1 - 5.7e-05 22.7 1.4 9e-05 22.1 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF4763 PF15960.5 KPI36611.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) GlcNAc_2-epim PF07221.11 KPI36611.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) TAF6_C PF07571.13 KPI36612.1 - 5.1e-27 94.0 0.2 1.4e-26 92.6 0.2 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KPI36612.1 - 8.8e-22 77.1 0.2 1.9e-21 76.0 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) GnsAB_toxin PF08178.11 KPI36612.1 - 0.033 14.1 0.1 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system DRIM PF07539.12 KPI36612.1 - 0.049 12.0 0.0 0.072 11.4 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis HEAT_EZ PF13513.6 KPI36612.1 - 0.11 13.0 0.5 53 4.5 0.1 3.9 3 1 1 4 4 4 0 HEAT-like repeat Laminin_I PF06008.14 KPI36613.1 - 0.0041 16.9 0.3 0.0041 16.9 0.3 5.5 3 2 2 5 5 5 2 Laminin Domain I DUF948 PF06103.11 KPI36613.1 - 0.017 15.4 34.4 0.079 13.2 0.9 6.9 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) RasGAP_C PF03836.15 KPI36613.1 - 0.046 13.9 19.3 3 8.0 0.4 5.6 4 2 2 6 6 6 0 RasGAP C-terminus PKS_DE PF18369.1 KPI36613.1 - 0.073 13.6 0.1 0.28 11.8 0.1 2.1 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain DUF1664 PF07889.12 KPI36613.1 - 0.074 13.1 40.5 0.078 13.0 0.7 7.1 5 2 2 7 7 7 0 Protein of unknown function (DUF1664) Rota_NSP4 PF01452.16 KPI36613.1 - 0.13 12.0 0.7 0.5 10.0 0.7 2.0 1 0 0 1 1 1 0 Rotavirus non structural protein BLI1 PF17324.2 KPI36613.1 - 1.6 9.4 11.6 13 6.5 0.0 5.1 5 1 1 6 6 5 0 BLOC-1 interactor 1 Anti-adapt_IraP PF10796.9 KPI36613.1 - 1.9 9.1 0.0 1.9 9.1 0.0 5.5 5 1 1 6 6 6 0 Sigma-S stabilisation anti-adaptor protein Filament PF00038.21 KPI36613.1 - 4.1 6.9 45.5 0.99 8.9 2.2 5.3 2 2 1 4 4 4 0 Intermediate filament protein TolA_bind_tri PF16331.5 KPI36613.1 - 4.6 7.4 29.6 2.5 8.2 1.2 6.5 6 1 1 7 7 7 0 TolA binding protein trimerisation T2SSF PF00482.23 KPI36613.1 - 5.2 7.0 5.2 4 7.4 1.7 2.6 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Lzipper-MIP1 PF14389.6 KPI36613.1 - 9.4 6.6 15.2 9.5 6.6 0.6 4.6 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 ADH_N PF08240.12 KPI36614.1 - 2e-27 95.2 6.1 3.9e-27 94.3 6.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI36614.1 - 6e-19 68.3 0.5 1e-18 67.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPI36614.1 - 1e-06 28.2 2.4 2e-06 27.2 2.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 KPI36614.1 - 2.2e-06 27.5 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KPI36614.1 - 3.2e-05 25.0 0.5 0.00015 22.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI36614.1 - 0.00017 21.2 0.7 0.00028 20.4 0.7 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Ig_C17orf99 PF17736.1 KPI36614.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 C17orf99 Ig domain p450 PF00067.22 KPI36615.1 - 3.9e-82 276.4 0.0 4.8e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vps26 PF03643.15 KPI36616.1 - 3e-130 433.2 0.5 3.5e-130 433.0 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KPI36616.1 - 0.00049 20.2 1.0 0.22 11.6 1.0 3.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ceramidase PF05875.12 KPI36617.1 - 1.8e-52 178.4 0.0 2.2e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Ceramidase LVIVD PF08309.11 KPI36618.1 - 0.0012 18.1 1.5 0.88 8.9 0.0 3.7 4 0 0 4 4 4 2 LVIVD repeat ADH_N PF08240.12 KPI36619.1 - 8.3e-34 115.8 0.6 1.4e-33 115.1 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI36619.1 - 3.7e-24 85.2 0.8 1.3e-23 83.4 0.3 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI36619.1 - 1.5e-09 39.0 0.1 3.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KPI36619.1 - 0.039 13.4 0.3 0.069 12.6 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KPI36619.1 - 0.074 12.3 0.6 0.13 11.6 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Nsp3_PL2pro PF12124.8 KPI36619.1 - 0.12 12.2 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain Metallophos PF00149.28 KPI36620.1 - 1e-13 52.3 0.2 1.5e-13 51.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI36620.1 - 4.8e-07 30.1 0.9 7.2e-07 29.6 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Gryzun PF07919.12 KPI36621.1 - 1.7e-141 472.9 0.5 2e-140 469.4 0.5 2.4 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KPI36621.1 - 2.7e-53 181.2 0.2 4.7e-53 180.4 0.2 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 KPI36621.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking Cas1_AcylT PF07779.12 KPI36622.1 - 1.1e-102 344.5 27.0 1.1e-102 344.5 27.0 2.2 1 1 1 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p MFS_1 PF07690.16 KPI36622.1 - 8.4e-23 80.9 43.0 8.4e-23 80.9 43.0 3.0 3 1 1 4 4 4 1 Major Facilitator Superfamily MARVEL PF01284.23 KPI36623.1 - 0.00064 19.8 10.7 0.0017 18.4 10.7 1.5 1 1 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.19 KPI36623.1 - 0.0014 18.6 1.2 0.0016 18.3 1.2 1.2 1 0 0 1 1 1 1 VIT family zf-MYND PF01753.18 KPI36624.1 - 1.2e-08 34.9 12.6 2.4e-08 33.9 12.6 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KPI36624.1 - 0.64 9.9 10.2 1.3 9.0 10.2 1.6 1 0 0 1 1 1 0 HIT zinc finger UFD1 PF03152.14 KPI36625.1 - 1.6e-66 223.0 0.0 2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 KPI36625.1 - 0.032 14.4 0.0 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Pex16 PF08610.10 KPI36626.1 - 3.4e-104 348.5 0.4 7.7e-85 284.9 0.0 2.0 1 1 1 2 2 2 2 Peroxisomal membrane protein (Pex16) Methyltransf_11 PF08241.12 KPI36627.1 - 7.8e-13 48.9 0.2 3.9e-12 46.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI36627.1 - 1.8e-11 44.6 0.1 8.4e-11 42.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI36627.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI36627.1 - 5.2e-08 33.5 0.2 1.3e-07 32.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI36627.1 - 2.5e-06 27.4 0.0 1.4e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KPI36627.1 - 0.0064 16.1 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 KPI36627.1 - 0.0075 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KPI36627.1 - 0.051 12.9 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MCR_gamma PF02240.16 KPI36628.1 - 0.076 12.2 0.1 2.2 7.4 0.1 2.2 1 1 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit DUF445 PF04286.12 KPI36629.1 - 3.2e-05 23.9 2.4 5.8e-05 23.1 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Ge1_WD40 PF16529.5 KPI36629.1 - 0.085 11.8 0.0 0.71 8.8 0.0 2.2 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SF-assemblin PF06705.11 KPI36629.1 - 2.6 7.3 7.4 0.78 9.0 1.1 2.2 2 0 0 2 2 2 0 SF-assemblin/beta giardin Abhydrolase_6 PF12697.7 KPI36630.1 - 2.7e-07 31.4 2.9 3.9e-07 30.9 2.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI36630.1 - 0.00018 21.2 0.1 0.00046 19.9 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI36630.1 - 0.00066 19.0 0.0 0.096 11.9 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KPI36630.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 KPI36630.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 KPI36631.1 - 2.7e-10 39.7 1.1 4.6e-10 39.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Serglycin PF04360.12 KPI36631.1 - 0.032 14.2 0.4 0.067 13.1 0.4 1.5 1 0 0 1 1 1 0 Serglycin Peptidase_S58 PF03576.14 KPI36632.1 - 1.7e-95 320.0 1.6 2.1e-95 319.7 1.6 1.1 1 0 0 1 1 1 1 Peptidase family S58 Rpp20 PF12328.8 KPI36633.1 - 3.8e-37 127.3 16.6 3.3e-36 124.3 16.6 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KPI36633.1 - 4e-16 58.6 0.7 6.6e-16 57.9 0.7 1.4 1 0 0 1 1 1 1 Alba ATG2_CAD PF13329.6 KPI36633.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF2345 PF10106.9 KPI36634.1 - 0.13 12.1 0.1 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) ADH_zinc_N PF00107.26 KPI36636.1 - 2.2e-06 27.7 0.0 4.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI36636.1 - 7.1e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ATG16 PF08614.11 KPI36637.1 - 0.0025 18.0 12.9 0.0025 18.0 12.9 3.9 1 1 2 4 4 2 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KPI36637.1 - 0.0037 17.3 4.3 0.0037 17.3 4.3 3.6 1 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein FH2 PF02181.23 KPI36637.1 - 0.06 12.4 9.0 0.34 10.0 7.9 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain BLOC1_2 PF10046.9 KPI36637.1 - 0.075 13.3 9.2 0.08 13.2 1.6 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prismane PF03063.20 KPI36637.1 - 0.12 11.0 1.7 0.18 10.5 1.7 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family L27 PF02828.16 KPI36637.1 - 0.17 11.6 1.8 0.22 11.3 0.3 2.0 2 0 0 2 2 2 0 L27 domain DctQ PF04290.12 KPI36637.1 - 0.19 11.7 4.7 0.3 11.0 4.7 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF5601 PF18151.1 KPI36637.1 - 0.22 11.9 1.6 4.5 7.7 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) V_ATPase_I PF01496.19 KPI36637.1 - 2.5 5.9 12.0 0.34 8.8 7.8 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KPI36637.1 - 3 8.4 5.0 16 6.1 0.9 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KPI36637.1 - 3.3 7.9 12.9 0.4 10.9 6.0 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 KPI36637.1 - 4.6 6.4 13.7 2.2 7.4 1.2 2.6 1 1 1 2 2 2 0 TMPIT-like protein DUF4200 PF13863.6 KPI36637.1 - 4.7 7.6 21.7 0.11 13.0 11.9 2.4 1 1 1 2 2 1 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 KPI36638.1 - 0.41 10.9 2.9 0.97 9.7 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) p450 PF00067.22 KPI36639.1 - 1.5e-61 208.6 0.0 2e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4437 PF14499.6 KPI36640.1 - 0.099 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) EthD PF07110.11 KPI36641.1 - 5.6e-12 46.7 0.0 7.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPI36641.1 - 2.4e-05 24.8 0.0 3.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase adh_short_C2 PF13561.6 KPI36642.1 - 2e-62 210.8 7.7 2.2e-62 210.7 7.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36642.1 - 1.9e-46 158.0 6.0 2.4e-46 157.7 6.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36642.1 - 1.2e-12 48.1 3.6 1.7e-12 47.6 3.6 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KPI36642.1 - 4.6e-05 23.7 0.2 9.9e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KPI36642.1 - 0.00047 20.1 0.4 0.00097 19.1 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KPI36642.1 - 0.0021 17.6 0.6 0.0086 15.6 0.3 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KPI36642.1 - 0.0023 18.0 0.6 0.0067 16.5 0.4 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KPI36642.1 - 0.0034 16.5 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 KPI36642.1 - 0.0052 16.2 0.1 0.0088 15.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family GDP_Man_Dehyd PF16363.5 KPI36642.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Phage_lysis PF03245.13 KPI36642.1 - 0.014 15.5 1.9 3.1 7.9 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein 3Beta_HSD PF01073.19 KPI36642.1 - 0.027 13.5 0.2 0.12 11.4 0.0 2.0 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.12 KPI36642.1 - 0.052 14.3 0.2 0.16 12.8 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_6 PF13480.7 KPI36643.1 - 0.034 14.3 0.3 0.056 13.6 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.31 KPI36644.1 - 1.2e-13 51.0 1.9 1.1e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPI36644.1 - 2e-07 31.1 3.1 0.00026 21.2 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain COesterase PF00135.28 KPI36645.1 - 2.3e-45 155.5 0.0 5.7e-45 154.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.16 KPI36646.1 - 3.3e-25 88.7 21.7 1.8e-24 86.3 21.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5391 PF17369.2 KPI36646.1 - 0.11 12.6 0.7 8.1 6.5 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5391) LtrA PF06772.11 KPI36647.1 - 4.9e-37 128.0 22.2 6.8e-37 127.5 22.2 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) V_ATPase_I PF01496.19 KPI36647.1 - 0.06 11.3 0.1 0.1 10.5 0.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APH PF01636.23 KPI36648.1 - 1.4e-17 64.4 0.8 6.4e-17 62.3 0.8 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family MitoNEET_N PF10660.9 KPI36648.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus ABM PF03992.16 KPI36649.1 - 2.9e-06 27.3 0.1 4.4e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Mak10 PF04112.13 KPI36650.1 - 7.6e-59 198.0 0.0 1.5e-58 197.1 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FAD_binding_2 PF00890.24 KPI36651.1 - 3.2e-79 267.0 0.1 3.8e-79 266.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI36651.1 - 1.8e-11 44.3 1.3 1.5e-10 41.2 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPI36651.1 - 2.1e-10 40.5 0.1 3.6e-08 33.2 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPI36651.1 - 2.6e-05 23.6 0.3 0.00012 21.4 0.3 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KPI36651.1 - 7.8e-05 22.0 0.1 0.00039 19.7 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI36651.1 - 0.00016 21.8 0.1 0.00045 20.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPI36651.1 - 0.00042 19.1 1.2 0.00059 18.7 0.4 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KPI36651.1 - 0.0013 17.9 0.6 0.009 15.1 0.8 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI36651.1 - 0.033 13.4 0.1 0.071 12.4 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 KPI36651.1 - 0.095 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.7 KPI36651.1 - 0.11 13.0 1.9 0.15 12.6 0.6 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chs7 PF12271.8 KPI36652.1 - 8.5e-109 363.3 3.3 9.5e-109 363.2 3.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Herpes_UL79 PF03049.14 KPI36652.1 - 0.06 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UL79 family DUF202 PF02656.15 KPI36653.1 - 1e-10 41.9 5.1 1e-10 41.9 5.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MgtE PF01769.16 KPI36653.1 - 0.043 14.2 0.5 0.07 13.5 0.5 1.2 1 0 0 1 1 1 0 Divalent cation transporter MCM_bind PF09739.9 KPI36653.1 - 2.3 6.5 4.7 3.4 6.0 4.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Menin PF05053.13 KPI36653.1 - 4.1 5.7 6.7 5.7 5.2 6.7 1.1 1 0 0 1 1 1 0 Menin Sec10 PF07393.11 KPI36655.1 - 1.8e-175 585.4 0.0 5.5e-174 580.4 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec10 GAS PF13851.6 KPI36655.1 - 0.016 14.6 1.0 0.034 13.5 1.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 KPI36655.1 - 0.018 15.1 1.3 8.9 6.4 0.3 3.0 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FAM184 PF15665.5 KPI36655.1 - 0.054 13.3 1.6 0.13 12.1 1.6 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B zf-PHD-like PF15446.6 KPI36655.1 - 0.14 11.7 0.2 4.9 6.8 0.1 2.5 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Med21 PF11221.8 KPI36655.1 - 7.9 6.7 6.4 1.9 8.7 0.9 2.6 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Fungal_trans PF04082.18 KPI36656.1 - 7.2e-05 21.9 0.1 0.00014 21.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Retinal PF15449.6 KPI36656.1 - 0.013 13.4 0.2 0.019 12.8 0.2 1.1 1 0 0 1 1 1 0 Retinal protein Methyltransf_25 PF13649.6 KPI36659.1 - 3.2e-12 47.0 0.1 7.2e-12 45.9 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI36659.1 - 1.3e-11 45.0 0.1 2e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI36659.1 - 2e-10 41.3 0.0 3.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI36659.1 - 3.3e-09 36.7 0.0 4.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI36659.1 - 8.6e-09 35.4 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI36659.1 - 6.9e-06 25.6 0.0 9.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KPI36659.1 - 8.9e-06 25.2 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Rsm22 PF09243.10 KPI36659.1 - 0.00014 21.2 0.0 0.0002 20.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 KPI36659.1 - 0.002 17.7 0.3 0.0057 16.2 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KPI36659.1 - 0.0039 16.7 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 KPI36659.1 - 0.069 12.6 0.0 0.6 9.5 0.0 2.1 1 1 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 KPI36659.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KPI36659.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 KPI36659.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent CheR PF01739.18 KPI36659.1 - 0.2 11.1 0.9 1 8.8 0.3 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Brix PF04427.18 KPI36660.1 - 1e-27 97.5 0.0 1.3e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain ACBP PF00887.19 KPI36661.1 - 7.1e-19 67.8 0.0 3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Acyl CoA binding protein FERM_M PF00373.18 KPI36661.1 - 0.018 15.5 0.8 0.047 14.1 0.1 1.9 2 0 0 2 2 2 0 FERM central domain HTH_9 PF08221.11 KPI36662.1 - 2.5e-10 40.3 3.2 1.4e-06 28.3 0.6 3.3 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KPI36662.1 - 7.6e-05 22.5 0.0 0.0027 17.5 0.1 2.9 3 0 0 3 3 3 1 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.13 KPI36662.1 - 0.0028 17.4 0.0 0.055 13.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 Dimerisation2 PF16864.5 KPI36662.1 - 0.028 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain TIP49 PF06068.13 KPI36663.1 - 1.8e-145 484.6 4.2 2.7e-145 484.0 4.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KPI36663.1 - 7.4e-22 77.3 0.5 2e-21 75.9 0.3 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KPI36663.1 - 4.3e-07 30.4 0.3 0.00033 21.1 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPI36663.1 - 6e-07 29.3 0.4 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI36663.1 - 7.3e-06 26.5 0.1 3.7e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 KPI36663.1 - 1.2e-05 24.8 0.7 2.2e-05 24.0 0.7 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KPI36663.1 - 0.0011 18.4 0.7 0.015 14.7 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KPI36663.1 - 0.015 15.6 1.3 1.5 9.1 1.3 2.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KPI36663.1 - 0.017 15.1 0.1 1.4 8.9 0.0 2.8 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI36663.1 - 0.026 14.8 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KPI36663.1 - 0.036 13.8 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KPI36663.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain PEMT PF04191.13 KPI36664.1 - 1.5e-27 96.1 1.8 2.7e-27 95.3 1.8 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Acetyltransf_1 PF00583.25 KPI36665.1 - 2.7e-08 34.0 0.0 1.9e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI36665.1 - 4.9e-06 26.9 0.0 5.1e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI36665.1 - 9.1e-06 25.6 0.1 0.0093 15.9 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain PBP1_TM PF14812.6 KPI36665.1 - 0.003 17.9 1.2 0.0051 17.1 1.2 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Gar1 PF04410.14 KPI36665.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Rrn6 PF10214.9 KPI36665.1 - 2.5 6.5 6.4 0.24 9.8 2.0 1.4 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor 2-oxoacid_dh PF00198.23 KPI36666.1 - 3e-60 203.6 0.4 6.9e-34 117.3 0.1 2.2 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KPI36666.1 - 3.9e-18 65.1 0.9 1.1e-17 63.6 0.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KPI36666.1 - 2.2e-12 47.1 0.1 5e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KPI36666.1 - 0.0081 16.0 0.0 0.58 10.0 0.1 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like NAP PF00956.18 KPI36666.1 - 0.18 11.0 0.9 0.29 10.3 0.4 1.5 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) SspB PF04386.13 KPI36666.1 - 0.27 11.1 5.7 0.037 13.9 1.6 1.7 2 0 0 2 2 2 0 Stringent starvation protein B Dor1 PF04124.12 KPI36667.1 - 0.00037 19.3 1.5 0.0013 17.5 1.5 1.9 1 0 0 1 1 1 1 Dor1-like family SHE3 PF17078.5 KPI36667.1 - 0.36 10.5 6.1 0.15 11.7 0.9 2.9 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 Lectin_N PF03954.14 KPI36667.1 - 0.64 9.8 10.1 1.5 8.6 0.6 4.3 4 1 1 5 5 5 0 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.6 KPI36667.1 - 1.9 8.9 14.3 4.2 7.8 1.1 4.0 4 1 0 4 4 4 0 Syntaxin-like protein DUF3461 PF11944.8 KPI36667.1 - 2.2 8.4 4.0 7.7 6.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) DUF1664 PF07889.12 KPI36667.1 - 2.6 8.1 14.2 17 5.4 0.8 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KPI36667.1 - 3.6 7.8 16.0 0.35 11.0 2.8 4.0 2 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KPI36667.1 - 4.6 7.6 6.9 34 4.8 0.7 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COX17 PF05051.13 KPI36668.1 - 7.1e-20 71.1 7.9 9e-20 70.8 7.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AAA PF00004.29 KPI36669.1 - 3.7e-17 63.0 0.0 8e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KPI36669.1 - 7.9e-17 61.8 0.2 3.6e-16 59.7 0.0 2.1 2 1 1 3 3 3 1 BCS1 N terminal RuvB_N PF05496.12 KPI36669.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI36669.1 - 0.0002 21.8 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KPI36669.1 - 0.00081 19.4 0.0 0.0056 16.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KPI36669.1 - 0.0039 17.5 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPI36669.1 - 0.0045 17.2 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KPI36669.1 - 0.0045 16.1 0.0 0.05 12.7 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KPI36669.1 - 0.0098 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPI36669.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KPI36669.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KPI36669.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPI36669.1 - 0.031 14.8 0.0 0.076 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KPI36669.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KPI36669.1 - 0.043 14.2 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KPI36669.1 - 0.051 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KPI36669.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KPI36669.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.6 KPI36669.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPI36669.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Herpes_gE PF02480.16 KPI36669.1 - 0.098 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ABC_tran PF00005.27 KPI36669.1 - 0.13 12.8 0.0 0.73 10.3 0.0 2.2 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 KPI36669.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Polyoma_lg_T_C PF06431.11 KPI36669.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus HalOD1 PF18545.1 KPI36669.1 - 0.16 12.3 0.0 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Halobacterial output domain 1 NACHT PF05729.12 KPI36669.1 - 0.17 11.8 0.1 0.39 10.6 0.0 1.6 2 0 0 2 2 1 0 NACHT domain Ring_hydroxyl_A PF00848.19 KPI36670.1 - 1.9e-26 93.4 0.1 3.9e-13 49.9 0.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KPI36670.1 - 1.1e-16 60.6 0.0 1.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain adh_short_C2 PF13561.6 KPI36671.1 - 3.3e-53 180.6 0.1 4.4e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36671.1 - 9.8e-36 123.0 0.2 1.2e-35 122.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36671.1 - 3.1e-07 30.5 0.4 9.8e-07 28.8 0.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI36671.1 - 0.00021 20.8 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KPI36671.1 - 0.0049 16.3 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Toprim PF01751.22 KPI36671.1 - 0.14 12.4 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Toprim domain AA_permease PF00324.21 KPI36672.1 - 8.6e-120 400.5 41.9 1.1e-119 400.2 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI36672.1 - 3e-36 125.2 42.2 3.7e-36 124.9 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease CDC14 PF08045.11 KPI36673.1 - 5.6e-80 268.5 1.1 1.9e-79 266.8 1.1 1.6 1 1 0 1 1 1 1 Cell division control protein 14, SIN component IpaC_SipC PF09599.10 KPI36673.1 - 0.086 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) DUF2390 PF09523.10 KPI36673.1 - 0.14 12.5 0.3 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) HAD_2 PF13419.6 KPI36674.1 - 3.7e-05 23.9 0.0 4.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI36674.1 - 4.2e-05 23.9 0.0 0.00015 22.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2922 PF11148.8 KPI36674.1 - 0.0092 15.7 0.1 0.036 13.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2922) UPF1_Zn_bind PF09416.10 KPI36675.1 - 9.2e-70 233.5 3.4 9.2e-70 233.5 3.4 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KPI36675.1 - 2.3e-59 200.4 0.0 4.6e-59 199.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPI36675.1 - 4.8e-55 187.2 3.6 1.1e-30 107.3 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KPI36675.1 - 3.5e-18 65.6 0.0 7.1e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KPI36675.1 - 3.3e-13 49.8 0.4 6.5e-12 45.6 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI36675.1 - 4.3e-11 43.3 0.1 1.9e-10 41.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KPI36675.1 - 3.1e-06 27.3 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KPI36675.1 - 3.9e-05 23.5 0.1 0.39 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KPI36675.1 - 0.00019 21.3 0.0 0.00052 19.9 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KPI36675.1 - 0.0003 20.4 0.1 0.0037 16.8 0.1 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KPI36675.1 - 0.0018 17.6 0.2 0.028 13.7 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KPI36675.1 - 0.0053 16.0 0.0 0.64 9.1 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.29 KPI36675.1 - 0.0068 16.2 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 KPI36675.1 - 0.02 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 KPI36675.1 - 0.038 13.3 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA PF00004.29 KPI36675.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L14e PF01929.17 KPI36675.1 - 0.1 13.1 0.5 0.29 11.7 0.0 2.0 2 0 0 2 2 1 0 Ribosomal protein L14 AAA_22 PF13401.6 KPI36675.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ribosomal_S13_N PF08069.12 KPI36675.1 - 0.12 12.4 0.2 0.42 10.7 0.0 2.1 2 0 0 2 2 1 0 Ribosomal S13/S15 N-terminal domain PhoH PF02562.16 KPI36675.1 - 0.14 11.6 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein zf-RanBP PF00641.18 KPI36675.1 - 3.6 7.0 7.0 0.46 9.9 2.0 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others UQ_con PF00179.26 KPI36676.1 - 3.3e-17 62.5 0.0 3.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPI36676.1 - 0.022 15.1 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain AXE1 PF05448.12 KPI36677.1 - 2.1e-08 33.2 0.0 5.8e-06 25.2 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KPI36677.1 - 1.7e-07 31.1 0.1 3.1e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPI36677.1 - 2.3e-06 27.4 0.3 5e-06 26.3 0.3 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KPI36677.1 - 2.7e-06 27.0 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPI36677.1 - 6.6e-05 23.6 0.0 9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KPI36677.1 - 0.059 13.3 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KPI36677.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 KPI36678.1 - 1.7e-10 40.3 0.0 3.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI36678.1 - 9.3e-07 28.9 8.8 1.6e-06 28.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.18 KPI36679.1 - 1.9e-30 106.4 0.0 2.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Scramblase PF03803.15 KPI36680.1 - 2.6e-49 167.5 0.0 2.2e-47 161.2 0.0 2.8 1 1 0 1 1 1 1 Scramblase FOXP-CC PF16159.5 KPI36681.1 - 0.091 13.4 10.2 1.4 9.6 4.2 3.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KPI36681.1 - 0.14 12.7 1.0 0.59 10.7 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain TRAPPC10 PF12584.8 KPI36682.1 - 3.2e-15 56.2 0.0 1.6e-14 53.9 0.0 2.2 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 BatD PF13584.6 KPI36682.1 - 0.079 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance p450 PF00067.22 KPI36683.1 - 3.5e-53 181.0 0.0 5.5e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Get5_C PF18514.1 KPI36684.1 - 0.31 10.8 1.6 1.1 9.0 0.1 2.5 3 0 0 3 3 3 0 Get5 C-terminal domain ABC_tran PF00005.27 KPI36685.1 - 2.9e-27 95.9 0.0 4.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KPI36685.1 - 1.5e-12 47.4 24.0 2e-12 46.9 24.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KPI36685.1 - 1.6e-09 38.0 0.0 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPI36685.1 - 0.0017 18.9 0.1 0.0034 17.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KPI36685.1 - 0.0035 17.3 0.1 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KPI36685.1 - 0.0036 17.0 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KPI36685.1 - 0.06 12.8 0.1 0.31 10.5 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KPI36685.1 - 0.11 12.1 0.0 7.6 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain EthD PF07110.11 KPI36686.1 - 7.1e-06 27.1 1.2 1.5e-05 26.0 1.2 1.5 1 1 0 1 1 1 1 EthD domain GYF PF02213.16 KPI36687.1 - 1e-09 37.9 1.4 1.7e-09 37.2 0.7 1.8 2 0 0 2 2 2 1 GYF domain Ribosomal_60s PF00428.19 KPI36688.1 - 0.33 11.6 5.2 0.56 10.8 5.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRI12 PF06609.13 KPI36689.1 - 1.5e-25 89.7 25.0 2e-25 89.3 25.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI36689.1 - 1.8e-25 89.6 53.2 3e-24 85.6 47.1 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36689.1 - 1.1e-06 27.9 13.0 1.1e-06 27.9 13.0 3.7 3 1 0 4 4 4 1 Sugar (and other) transporter DUF1772 PF08592.11 KPI36689.1 - 0.032 14.5 1.1 0.032 14.5 1.1 5.2 2 1 2 5 5 5 0 Domain of unknown function (DUF1772) G_glu_transpept PF01019.21 KPI36690.1 - 1.1e-122 410.4 0.0 2.3e-114 383.0 0.0 2.2 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase WD40 PF00400.32 KPI36692.1 - 1.2e-15 57.6 5.1 0.00043 21.0 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 KPI36692.1 - 0.001 17.8 0.1 0.25 9.9 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KPI36692.1 - 0.025 14.9 0.1 0.22 11.8 0.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NifQ PF04891.12 KPI36693.1 - 0.0065 16.8 0.1 0.049 14.0 0.0 2.1 2 1 0 2 2 2 1 NifQ TPR_12 PF13424.6 KPI36696.1 - 9.7e-09 35.4 9.6 0.016 15.5 1.6 5.5 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPI36696.1 - 1e-08 34.6 5.6 0.0064 16.5 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPI36696.1 - 4e-08 33.4 13.8 0.083 13.8 0.0 6.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI36696.1 - 4.7e-07 29.5 0.2 0.025 14.8 0.0 5.3 6 1 0 6 6 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPI36696.1 - 5e-07 29.3 0.1 0.21 11.5 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI36696.1 - 3.2e-06 27.7 2.3 0.27 11.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI36696.1 - 7.7e-06 25.6 6.9 0.12 12.5 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPI36696.1 - 2.6e-05 24.6 15.0 0.3 11.6 1.1 5.2 5 1 0 5 5 4 2 Tetratricopeptide repeat DUF4192 PF13830.6 KPI36696.1 - 8.6e-05 22.7 11.1 0.055 13.5 0.4 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4192) TPR_4 PF07721.14 KPI36696.1 - 0.00041 20.7 11.4 1.3 9.9 0.6 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPI36696.1 - 0.0026 17.2 5.3 0.057 12.8 2.0 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 KPI36696.1 - 0.0078 15.9 0.1 1.6 8.5 0.0 3.3 4 0 0 4 4 4 1 TPR repeat ANAPC3 PF12895.7 KPI36696.1 - 0.0099 16.1 0.1 7.6 6.8 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KPI36696.1 - 0.02 14.8 15.8 0.021 14.7 0.5 5.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KPI36696.1 - 0.6 10.3 0.0 0.6 10.3 0.0 3.5 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI36696.1 - 0.88 10.3 6.4 34 5.4 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat RVT_1 PF00078.27 KPI36697.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_trans PF04082.18 KPI36698.1 - 6.9e-19 67.9 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI36698.1 - 2.2e-06 27.7 10.1 3.9e-06 26.9 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ad_cyc_g-alpha PF08509.11 KPI36698.1 - 0.038 13.7 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain RdRP PF05183.12 KPI36699.1 - 1.5e-105 354.0 0.0 2e-105 353.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ATP-synt_Eps PF04627.13 KPI36700.1 - 1.4e-22 79.4 0.5 1.9e-22 78.9 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain adh_short_C2 PF13561.6 KPI36701.1 - 5.5e-52 176.6 3.0 7.1e-52 176.3 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36701.1 - 7.5e-38 129.9 1.2 1.1e-37 129.4 1.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36701.1 - 4.8e-08 33.1 0.6 7.1e-08 32.6 0.6 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KPI36701.1 - 0.1 12.4 0.1 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F_actin_cap_B PF01115.17 KPI36702.1 - 1.1e-77 260.9 0.0 1.4e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit AAA PF00004.29 KPI36703.1 - 2e-16 60.6 0.2 5.2e-16 59.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KPI36703.1 - 1e-15 57.9 0.1 1.2e-14 54.5 0.0 2.6 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KPI36703.1 - 8.5e-14 51.7 0.0 2.5e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KPI36703.1 - 3.8e-10 40.0 0.0 8.3e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KPI36703.1 - 6.7e-07 29.2 0.0 1.9e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KPI36703.1 - 9.6e-07 29.1 0.0 3.2e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 KPI36703.1 - 2.4e-06 27.5 0.1 5.9e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KPI36703.1 - 2.7e-06 27.9 0.0 3e-05 24.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI36703.1 - 3.4e-06 27.4 0.1 2.5e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KPI36703.1 - 7.1e-06 25.4 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KPI36703.1 - 1.3e-05 25.1 0.1 5e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KPI36703.1 - 6.3e-05 22.8 0.0 0.00024 20.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPI36703.1 - 0.00014 21.9 0.5 0.00045 20.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KPI36703.1 - 0.00021 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI36703.1 - 0.00053 20.4 0.1 0.0017 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KPI36703.1 - 0.00053 20.0 0.0 0.11 12.5 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KPI36703.1 - 0.00059 19.7 0.1 0.0023 17.8 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KPI36703.1 - 0.0014 18.1 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 KPI36703.1 - 0.0028 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Stork_head PF10264.9 KPI36703.1 - 0.0063 16.7 0.2 13 6.0 0.0 3.5 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain DEAD PF00270.29 KPI36703.1 - 0.0068 16.2 0.0 0.059 13.1 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.6 KPI36703.1 - 0.0099 16.1 0.0 0.021 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KPI36703.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KPI36703.1 - 0.023 14.1 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 KPI36703.1 - 0.04 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KPI36703.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KPI36703.1 - 0.051 12.9 0.1 0.15 11.5 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KPI36703.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPI36703.1 - 0.085 13.3 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KPI36703.1 - 0.089 12.5 0.0 0.69 9.6 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 KPI36703.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KPI36703.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KPI36703.1 - 0.12 12.3 0.3 1.6 8.6 0.1 2.4 2 1 0 2 2 1 0 NACHT domain ABC_tran PF00005.27 KPI36704.1 - 5.5e-19 69.1 0.6 1e-18 68.2 0.6 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KPI36704.1 - 4.2e-11 43.2 2.8 1.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KPI36704.1 - 1e-09 38.0 9.6 4.2e-09 36.0 7.3 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KPI36704.1 - 2.4e-07 30.4 0.4 3.1e-05 23.5 0.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI36704.1 - 0.0004 20.1 0.5 0.00098 18.8 0.5 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 KPI36704.1 - 0.063 12.4 0.0 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 KPI36704.1 - 0.12 12.9 1.4 0.17 12.3 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KPI36704.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KPI36704.1 - 0.12 12.7 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain CENP-F_N PF10481.9 KPI36704.1 - 0.17 11.5 0.4 0.27 10.8 0.4 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain CAF1C_H4-bd PF12265.8 KPI36705.1 - 2e-28 98.4 0.3 1.3e-27 95.8 0.1 2.4 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KPI36705.1 - 8.5e-25 86.5 12.8 2.7e-05 24.8 0.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI36705.1 - 7.4e-05 23.0 1.2 0.29 11.5 0.1 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain FA_desaturase PF00487.24 KPI36706.1 - 1e-24 87.8 21.1 2.7e-24 86.4 21.1 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KPI36706.1 - 0.00019 21.6 0.0 0.00039 20.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Peptidase_M16 PF00675.20 KPI36707.1 - 1e-16 61.3 0.0 1.9e-16 60.4 0.0 1.5 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KPI36707.1 - 2.8e-09 37.2 0.0 5.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain HET PF06985.11 KPI36708.1 - 2e-30 106.0 0.9 5.2e-30 104.7 0.9 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LSM14 PF12701.7 KPI36709.1 - 2.4e-22 78.8 0.0 3.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KPI36709.1 - 1.3e-14 54.9 5.9 1.3e-14 54.9 5.9 2.4 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KPI36709.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 KPI36709.1 - 0.61 10.8 22.0 1.1 10.0 18.4 2.4 2 0 0 2 2 2 0 Glycine rich protein family MAPEG PF01124.18 KPI36710.1 - 9.7e-09 35.2 0.7 2e-08 34.2 0.7 1.5 1 0 0 1 1 1 1 MAPEG family DUF883 PF05957.13 KPI36710.1 - 0.068 13.8 0.7 0.14 12.8 0.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KPI36710.1 - 0.13 12.8 0.2 0.22 12.1 0.2 1.3 1 0 0 1 1 1 0 YtxH-like protein DUF4188 PF13826.6 KPI36711.1 - 1.2e-26 93.4 0.2 1.7e-26 92.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KPI36711.1 - 1.4e-06 27.9 0.1 1.9e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase DUF3291 PF11695.8 KPI36711.1 - 0.021 14.5 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Pro_isomerase PF00160.21 KPI36713.1 - 8.4e-31 107.4 0.0 2e-30 106.1 0.0 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lin-8 PF03353.15 KPI36713.1 - 2.4 7.6 4.7 3 7.3 3.3 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Nucleo_P87 PF07267.11 KPI36713.1 - 3.6 6.3 6.2 4.9 5.9 6.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MAJIN PF15077.6 KPI36713.1 - 6.5 6.5 7.9 13 5.5 7.9 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein ABC2_membrane PF01061.24 KPI36714.1 - 1.2e-61 207.8 46.0 1e-39 136.2 16.4 3.6 3 0 0 3 3 3 3 ABC-2 type transporter ABC_tran PF00005.27 KPI36714.1 - 1.6e-35 122.6 0.0 1.2e-17 64.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPI36714.1 - 1.7e-29 101.6 6.1 1.4e-25 89.0 0.0 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPI36714.1 - 2e-12 47.5 0.5 1.5e-11 44.8 0.0 2.8 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 KPI36714.1 - 1.6e-06 28.6 0.1 0.0036 17.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KPI36714.1 - 6.4e-06 26.2 0.0 0.089 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPI36714.1 - 0.00074 19.2 0.5 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPI36714.1 - 0.0011 18.9 0.1 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KPI36714.1 - 0.0025 17.4 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPI36714.1 - 0.0027 18.3 0.0 0.068 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPI36714.1 - 0.0065 16.6 0.0 0.069 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPI36714.1 - 0.017 15.3 0.1 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KPI36714.1 - 0.019 14.4 0.0 17 4.8 0.0 3.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KPI36714.1 - 0.024 14.3 0.3 0.76 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPI36714.1 - 0.079 13.2 1.0 0.47 10.7 0.2 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KPI36714.1 - 0.095 12.3 0.7 0.44 10.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 KPI36714.1 - 0.11 11.6 32.9 0.027 13.6 14.6 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein NACHT PF05729.12 KPI36714.1 - 0.13 12.1 0.6 7.4 6.5 0.5 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KPI36714.1 - 0.38 11.2 0.0 0.38 11.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain EthD PF07110.11 KPI36715.1 - 4.8e-12 46.9 0.0 6.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPI36715.1 - 2.3e-07 31.3 0.0 2.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase AsnC_trans_reg PF01037.21 KPI36715.1 - 0.061 13.3 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Takusan PF04822.13 KPI36715.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Takusan Helicase_C PF00271.31 KPI36716.1 - 1.5e-21 76.8 0.1 4.3e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI36716.1 - 3.7e-21 75.9 0.0 7.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI36716.1 - 5.2e-16 58.9 0.0 1.5e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase NACHT PF05729.12 KPI36716.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NmrA PF05368.13 KPI36717.1 - 1.4e-21 77.1 0.4 1.9e-21 76.7 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36717.1 - 5.5e-17 62.3 1.6 7.7e-17 61.8 0.1 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPI36717.1 - 1e-05 25.2 0.1 0.059 12.8 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPI36717.1 - 7.3e-05 23.2 0.4 0.00035 21.0 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain PAGK PF15284.6 KPI36718.1 - 0.044 13.7 1.0 0.55 10.2 0.0 2.5 2 0 0 2 2 2 0 Phage-encoded virulence factor DUF4389 PF14333.6 KPI36718.1 - 0.35 10.8 6.5 0.065 13.2 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) LRR_4 PF12799.7 KPI36719.1 - 2.7 8.6 16.8 10 6.7 1.0 4.8 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) SET PF00856.28 KPI36720.1 - 7.2e-16 59.0 0.0 1.8e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 SET domain Metallophos PF00149.28 KPI36721.1 - 2.5e-36 126.1 0.1 4.4e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 KPI36721.1 - 0.12 12.1 1.6 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) ASXH PF13919.6 KPI36722.1 - 1e-18 67.7 0.0 1.5e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Asx homology domain MFS_1 PF07690.16 KPI36725.1 - 2.4e-26 92.5 31.0 2.4e-26 92.5 31.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DCB PF16213.5 KPI36726.1 - 3.2e-40 137.7 1.5 1.2e-39 135.8 1.5 2.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KPI36726.1 - 4.4e-18 65.7 5.7 5.5e-16 58.9 0.0 4.1 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KPI36726.1 - 2.4e-09 36.0 0.2 6.1e-09 34.6 0.1 1.7 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KPI36726.1 - 0.00022 21.0 1.4 0.023 14.5 0.0 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KPI36726.1 - 0.11 12.8 2.2 5.6 7.5 0.1 4.7 3 0 0 3 3 3 0 HEAT repeat Abhydrolase_3 PF07859.13 KPI36728.1 - 2.5e-35 122.3 0.0 3.9e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI36728.1 - 5.6e-05 22.2 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPI36728.1 - 0.00088 18.8 0.0 0.0026 17.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPI36728.1 - 0.036 14.6 0.8 0.098 13.2 0.8 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Conotoxin PF02950.17 KPI36729.1 - 0.0081 17.2 3.4 0.0081 17.2 3.4 1.8 2 0 0 2 2 2 1 Conotoxin AAA_33 PF13671.6 KPI36730.1 - 3.5e-13 49.9 0.0 4.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KPI36730.1 - 2.5e-12 47.2 0.0 3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KPI36730.1 - 5.2e-09 36.7 0.0 2.8e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KPI36730.1 - 1.6e-06 28.6 0.0 4.6e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KPI36730.1 - 3.9e-06 26.9 0.0 1e-05 25.5 0.0 1.7 2 1 0 2 2 2 1 Rad17 P-loop domain dNK PF01712.19 KPI36730.1 - 1.7e-05 24.8 0.2 0.018 14.9 0.0 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin PF02224.18 KPI36730.1 - 8.5e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase APS_kinase PF01583.20 KPI36730.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KPI36730.1 - 0.00026 21.4 0.4 0.0007 20.0 0.4 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KPI36730.1 - 0.00054 20.2 0.0 0.00099 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 KPI36730.1 - 0.0008 19.0 0.1 0.74 9.3 0.0 2.1 2 0 0 2 2 2 2 P-loop Nucleotide Kinase1 AAA_22 PF13401.6 KPI36730.1 - 0.002 18.4 0.1 0.0052 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KPI36730.1 - 0.0027 17.6 0.0 0.012 15.6 0.0 1.9 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KPI36730.1 - 0.0029 18.0 0.1 0.01 16.2 0.0 1.7 1 1 0 2 2 1 1 RNA helicase AAA_16 PF13191.6 KPI36730.1 - 0.0058 17.0 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain CoaE PF01121.20 KPI36730.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 KPI36730.1 - 0.0066 16.6 0.1 0.033 14.3 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.27 KPI36730.1 - 0.0074 16.8 0.1 0.015 15.8 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_11 PF13086.6 KPI36730.1 - 0.0087 15.9 0.4 0.043 13.6 0.4 1.8 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 KPI36730.1 - 0.0098 16.0 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_14 PF13173.6 KPI36730.1 - 0.013 15.5 0.0 0.098 12.7 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 KPI36730.1 - 0.014 14.9 0.0 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KPI36730.1 - 0.016 15.0 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KPI36730.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KPI36730.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IPT PF01745.16 KPI36730.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase RuvB_N PF05496.12 KPI36730.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KPI36730.1 - 0.039 13.9 0.2 0.16 11.9 0.1 1.8 1 1 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 KPI36730.1 - 0.041 13.2 0.1 0.07 12.4 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin PRK PF00485.18 KPI36730.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF4848 PF16140.5 KPI36730.1 - 0.071 12.7 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) NB-ARC PF00931.22 KPI36730.1 - 0.082 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KPI36730.1 - 0.095 11.7 0.2 0.43 9.6 0.0 2.0 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 KPI36730.1 - 0.1 13.0 1.1 1.1 9.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain ADK PF00406.22 KPI36730.1 - 0.1 12.7 0.3 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Thymidylate_kin PF02223.17 KPI36730.1 - 0.11 12.2 0.3 5.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 KPI36730.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KPI36730.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 KPI36730.1 - 0.17 11.5 0.6 4 7.0 0.0 2.3 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KPI36730.1 - 0.32 11.5 1.7 0.74 10.3 1.7 1.8 1 1 0 1 1 1 0 AAA domain Tetraspanin PF00335.20 KPI36731.1 - 0.077 12.7 1.1 0.11 12.2 1.1 1.2 1 0 0 1 1 1 0 Tetraspanin family Adeno_E3 PF06040.11 KPI36731.1 - 0.15 12.2 1.4 1.5 9.0 0.7 2.2 2 0 0 2 2 2 0 Adenovirus E3 protein FixQ PF05545.11 KPI36731.1 - 0.32 11.0 0.1 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ adh_short_C2 PF13561.6 KPI36732.1 - 5.3e-57 193.1 1.0 6.5e-57 192.8 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI36732.1 - 5.3e-53 179.4 0.2 6.8e-53 179.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI36732.1 - 1.4e-15 57.7 0.6 1.5e-14 54.3 0.1 2.0 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KPI36732.1 - 1.8e-05 24.3 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPI36732.1 - 0.00044 19.5 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI36732.1 - 0.00044 19.8 0.3 0.0018 17.8 0.1 2.0 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KPI36732.1 - 0.00046 20.1 0.1 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPI36732.1 - 0.0027 18.0 0.1 0.011 16.0 0.0 2.0 3 0 0 3 3 2 1 TrkA-N domain 3Beta_HSD PF01073.19 KPI36732.1 - 0.0064 15.5 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KPI36732.1 - 0.01 15.4 0.2 0.62 9.6 0.2 2.1 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 KPI36732.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.10 KPI36732.1 - 0.028 13.8 0.0 0.073 12.4 0.0 1.7 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Ldh_1_N PF00056.23 KPI36732.1 - 0.029 14.5 0.6 0.079 13.0 0.1 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KPI36732.1 - 0.048 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_11 PF08241.12 KPI36732.1 - 0.12 13.0 0.0 0.37 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_7 PF13241.6 KPI36732.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding CbiA PF01656.23 KPI36732.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ANAPC10 PF03256.16 KPI36734.1 - 2.7e-37 128.2 0.0 1.1e-36 126.3 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CAF20 PF17052.5 KPI36734.1 - 0.071 13.3 0.9 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 Cap associated factor MFS_1 PF07690.16 KPI36736.1 - 4.7e-40 137.6 34.6 6.1e-40 137.2 34.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36736.1 - 2.3e-16 59.7 2.1 2.3e-16 59.7 2.1 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI36736.1 - 4e-05 22.2 2.0 5.7e-05 21.7 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NARP1 PF12569.8 KPI36737.1 - 1.2e-188 628.3 23.5 3.8e-187 623.3 18.9 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 KPI36737.1 - 1.3e-12 47.4 19.4 0.14 13.0 0.0 11.0 8 3 3 11 11 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPI36737.1 - 5.5e-11 41.7 25.2 0.0045 17.0 0.1 9.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KPI36737.1 - 1.4e-09 38.5 20.9 0.16 12.6 0.0 8.1 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KPI36737.1 - 3.7e-08 33.8 30.6 0.046 14.2 0.0 7.4 8 1 0 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KPI36737.1 - 3.4e-07 30.2 8.8 0.043 14.2 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPI36737.1 - 2e-06 27.8 5.7 0.075 13.2 0.2 5.1 5 1 1 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI36737.1 - 4.2e-06 26.9 17.9 7.3e-05 22.9 1.3 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KPI36737.1 - 2.8e-05 24.3 19.7 1.3 9.4 2.3 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI36737.1 - 6.4e-05 22.9 26.1 0.0018 18.4 0.1 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPI36737.1 - 8.3e-05 22.2 7.1 0.00064 19.3 0.1 5.2 5 0 0 5 5 5 1 TPR repeat DUF2730 PF10805.8 KPI36737.1 - 0.0001 22.3 0.5 9.7 6.3 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2730) TPR_1 PF00515.28 KPI36737.1 - 0.00027 20.6 29.3 0.00069 19.3 0.1 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPI36737.1 - 0.00055 19.8 4.9 4 7.7 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 KPI36737.1 - 0.027 14.4 1.4 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPI36737.1 - 0.036 14.1 8.0 2.3 8.4 0.1 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KPI36737.1 - 0.22 12.2 21.8 17 6.3 0.1 8.7 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI36737.1 - 0.31 11.8 0.2 0.31 11.8 0.2 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Ada3 PF10198.9 KPI36738.1 - 3.5e-47 159.9 0.5 3.5e-47 159.9 0.5 2.3 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 CSTF2_hinge PF14327.6 KPI36738.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Prominin PF05478.11 KPI36738.1 - 5.1 4.9 4.2 0.92 7.4 0.1 1.6 2 0 0 2 2 2 0 Prominin Fungal_trans PF04082.18 KPI36740.1 - 9.7e-18 64.1 0.2 4.3e-17 62.0 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KPI36741.1 - 0.0009 18.3 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.16 KPI36742.1 - 1.4e-09 37.8 0.3 2.7e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KPI36742.1 - 1.1e-05 25.0 1.3 2.5e-05 23.8 1.3 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KPI36742.1 - 0.0014 18.5 0.8 0.0046 16.8 0.0 2.3 3 0 0 3 3 3 1 MarR family HTH_38 PF13936.6 KPI36742.1 - 0.012 15.4 0.3 0.027 14.2 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KPI36742.1 - 0.04 13.7 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 KPI36742.1 - 0.04 13.4 0.2 0.071 12.6 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Fungal_trans PF04082.18 KPI36743.1 - 2.5e-06 26.7 0.0 6.4e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRN9 PF10680.9 KPI36744.1 - 0.2 11.9 2.0 0.45 10.8 2.0 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor DUF4635 PF15466.6 KPI36745.1 - 0.13 11.8 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) NAD_binding_10 PF13460.6 KPI36746.1 - 1.2e-15 57.9 0.0 2.7e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPI36746.1 - 2.1e-13 50.4 0.0 3.3e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KPI36746.1 - 0.00042 20.7 0.1 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KPI36746.1 - 0.0018 19.1 0.1 0.0032 18.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold THF_DHG_CYH_C PF02882.19 KPI36746.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 KPI36746.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KPI36746.1 - 0.016 15.2 0.2 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 KPI36746.1 - 0.074 13.6 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Epimerase PF01370.21 KPI36746.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI36746.1 - 0.15 11.2 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein FMN_dh PF01070.18 KPI36747.1 - 8.3e-127 423.0 1.1 9.5e-127 422.8 1.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KPI36747.1 - 2.1e-09 36.8 1.0 2.5e-08 33.3 0.5 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KPI36747.1 - 4.3e-05 22.8 0.5 6.6e-05 22.2 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KPI36747.1 - 8.4e-05 22.1 2.1 0.00015 21.3 2.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KPI36747.1 - 0.00034 19.9 0.6 0.005 16.1 0.1 2.3 1 1 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KPI36747.1 - 0.00056 19.3 1.9 0.084 12.2 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KPI36747.1 - 0.00071 19.1 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.22 KPI36747.1 - 0.018 15.0 0.2 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 PA domain DUF3425 PF11905.8 KPI36748.1 - 2e-14 53.6 0.3 7.9e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) FMO-like PF00743.19 KPI36748.1 - 5.7e-08 31.6 0.2 2.6e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI36748.1 - 2.1e-05 24.7 1.0 3.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI36748.1 - 0.0001 21.6 0.0 0.00093 18.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) bZIP_1 PF00170.21 KPI36748.1 - 0.009 16.1 10.4 0.009 16.1 10.4 2.3 2 1 0 2 2 2 1 bZIP transcription factor HALZ PF02183.18 KPI36748.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper FB_lectin PF07367.11 KPI36748.1 - 0.12 12.3 0.7 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Fungal fruit body lectin DUF1640 PF07798.11 KPI36748.1 - 0.2 11.7 2.4 0.41 10.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Peptidase_C78 PF07910.13 KPI36750.1 - 1.5e-54 184.7 0.0 2e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 KPI36750.1 - 0.0067 16.7 0.2 0.016 15.5 0.2 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Hira PF07569.11 KPI36751.1 - 5.6e-84 281.3 0.4 1.2e-83 280.3 0.1 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split Band_7 PF01145.25 KPI36751.1 - 1.2e-28 100.3 0.2 1.9e-28 99.7 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family WD40 PF00400.32 KPI36751.1 - 2.7e-25 88.1 15.7 0.00011 22.9 0.0 8.4 7 1 1 8 8 8 5 WD domain, G-beta repeat Band_7_C PF16200.5 KPI36751.1 - 2.1e-18 66.1 0.1 5e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 ANAPC4_WD40 PF12894.7 KPI36751.1 - 6.9e-11 42.3 0.0 0.035 14.4 0.1 5.6 4 2 2 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KPI36751.1 - 0.00047 19.9 1.2 0.00061 19.6 0.1 1.8 2 0 0 2 2 2 1 HIRA B motif Ge1_WD40 PF16529.5 KPI36751.1 - 0.00066 18.7 0.0 0.17 10.8 0.0 4.2 3 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KPI36751.1 - 0.019 14.8 0.1 2.9 7.7 0.0 3.6 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KPI36751.1 - 0.17 11.2 0.0 0.43 9.9 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain IKI3 PF04762.12 KPI36751.1 - 0.18 9.8 0.0 0.31 9.0 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Pox_A11 PF05061.13 KPI36751.1 - 0.25 10.6 0.2 0.42 9.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF5109 PF17134.4 KPI36752.1 - 0.087 12.7 0.2 9.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5109) PALP PF00291.25 KPI36753.1 - 2.8e-44 151.7 5.4 3.3e-44 151.5 5.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F-box PF00646.33 KPI36755.1 - 0.0002 21.1 0.5 0.00036 20.3 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPI36755.1 - 0.0012 18.7 0.3 0.002 17.9 0.3 1.3 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KPI36755.1 - 0.0035 17.2 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box DUF3425 PF11905.8 KPI36757.1 - 3.5e-10 39.9 0.1 7e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) GrpE PF01025.19 KPI36757.1 - 0.79 9.4 5.0 0.27 10.9 2.3 1.5 2 0 0 2 2 2 0 GrpE Sugar_tr PF00083.24 KPI36758.1 - 1.6e-69 234.9 24.0 2e-69 234.7 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36758.1 - 6e-14 51.7 50.1 9.4e-10 37.9 29.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily CTI PF06934.11 KPI36758.1 - 0.094 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) QCR10 PF09796.9 KPI36758.1 - 1.5 8.9 5.0 0.68 10.0 0.3 3.0 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pro_CA PF00484.19 KPI36759.1 - 1.4e-07 31.9 0.0 2.8e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Ribosomal_S14 PF00253.21 KPI36760.1 - 1.6e-18 66.2 2.9 2.4e-18 65.6 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.11 KPI36760.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 QLQ Myb_DNA-binding PF00249.31 KPI36762.1 - 0.0001 22.4 0.3 0.00029 21.0 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF3723 PF12520.8 KPI36762.1 - 0.13 11.0 0.2 0.19 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Cyt-b5 PF00173.28 KPI36763.1 - 1.4e-06 28.4 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KPI36763.1 - 0.012 14.4 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KPI36763.1 - 0.089 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Sugar_tr PF00083.24 KPI36764.1 - 1.4e-88 297.7 18.0 1.8e-88 297.4 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36764.1 - 1.2e-22 80.4 41.9 3.5e-15 55.8 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KPI36764.1 - 0.88 9.5 10.1 0.17 11.8 5.5 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KPI36764.1 - 1.6 8.8 9.2 0.084 12.9 3.0 2.1 2 0 0 2 2 2 0 Glycine zipper OATP PF03137.20 KPI36764.1 - 2.6 6.3 12.5 0.32 9.2 0.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DIOX_N PF14226.6 KPI36765.1 - 1.8e-27 96.4 0.0 3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI36765.1 - 1.1e-15 58.0 0.1 2.9e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 KPI36766.1 - 9.3e-10 37.9 6.2 1e-09 37.8 6.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF5336 PF17270.2 KPI36766.1 - 0.24 11.0 4.5 0.12 12.0 1.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5336) DUF3405 PF11885.8 KPI36767.1 - 2e-172 574.4 0.2 2.8e-172 574.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) TcpQ PF10671.9 KPI36767.1 - 0.25 11.5 2.3 0.24 11.6 0.3 2.0 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q COX4_pro_2 PF07835.12 KPI36767.1 - 4.7 7.4 5.6 15 5.8 1.1 2.5 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV INSIG PF07281.12 KPI36768.1 - 0.049 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF1524 PF07510.11 KPI36769.1 - 1.3e-07 31.6 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Whi5 PF08528.11 KPI36771.1 - 2e-11 43.2 0.5 3.5e-11 42.4 0.5 1.4 1 0 0 1 1 1 1 Whi5 like RTC_insert PF05189.13 KPI36771.1 - 0.048 14.2 0.0 0.37 11.3 0.0 2.2 1 1 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Syntaxin PF00804.25 KPI36772.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Syntaxin zf-CCHC PF00098.23 KPI36773.1 - 0.0013 18.8 11.3 0.013 15.6 3.5 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KPI36773.1 - 1.5 8.8 8.0 0.12 12.3 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zinc_ribbon_4 PF13717.6 KPI36773.1 - 8.6 6.4 10.5 30 4.6 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IU_nuc_hydro PF01156.19 KPI36775.1 - 2.5e-74 250.6 0.0 3.1e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.22 KPI36776.1 - 1.3e-42 146.2 0.0 4.4e-40 137.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_q6 PF01058.22 KPI36778.1 - 1.2e-21 76.9 0.0 1.8e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HEAT PF02985.22 KPI36779.1 - 2.9e-39 129.7 14.6 0.013 15.7 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KPI36779.1 - 3.5e-36 123.5 5.1 2.6e-10 40.5 0.0 8.2 4 2 4 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 KPI36779.1 - 2.3e-13 50.5 0.9 0.00011 22.7 0.1 6.9 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KPI36779.1 - 3.3e-13 49.8 9.5 0.023 15.2 0.0 9.0 7 3 3 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 KPI36779.1 - 4.7e-08 33.2 10.8 0.052 13.6 0.1 5.7 4 1 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KPI36779.1 - 2e-06 26.7 5.6 0.00088 18.0 0.5 4.6 1 1 2 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 KPI36779.1 - 8.2e-06 26.0 4.7 1.2 9.3 0.1 4.8 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KPI36779.1 - 3.8e-05 23.4 0.8 0.042 13.4 0.0 4.2 2 2 2 4 4 4 1 CLASP N terminal TetR_C_16 PF17920.1 KPI36779.1 - 0.00056 20.1 0.1 10 6.4 0.0 4.0 2 1 1 3 3 3 2 Tetracyclin repressor-like, C-terminal domain Proteasom_PSMB PF10508.9 KPI36779.1 - 0.051 12.1 3.1 0.48 8.9 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DNA_alkylation PF08713.11 KPI36779.1 - 0.11 12.2 0.0 6.6 6.4 0.0 3.0 2 1 1 3 3 3 0 DNA alkylation repair enzyme IFRD PF05004.13 KPI36779.1 - 0.13 11.4 0.1 1 8.4 0.1 2.3 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) M11L PF11099.8 KPI36779.1 - 0.15 12.3 0.3 11 6.2 0.0 3.5 3 1 1 4 4 4 0 Apoptosis regulator M11L like Arm PF00514.23 KPI36779.1 - 0.15 12.1 3.9 4.9 7.3 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Asp PF00026.23 KPI36780.1 - 2.7e-22 79.6 2.8 3.6e-22 79.2 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KPI36780.1 - 0.021 15.4 0.4 0.24 12.1 0.4 2.5 1 1 0 1 1 1 0 Aspartyl protease DUF1345 PF07077.11 KPI36780.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) COesterase PF00135.28 KPI36781.1 - 1.7e-50 172.3 0.0 2.6e-50 171.8 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI36781.1 - 0.11 12.4 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold PIN_3 PF13470.6 KPI36782.1 - 0.13 13.0 0.3 0.57 11.0 0.3 2.1 1 1 0 1 1 1 0 PIN domain RVT_1 PF00078.27 KPI36782.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) OrfB_Zn_ribbon PF07282.11 KPI36783.1 - 0.55 10.2 2.6 1.3 9.0 2.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A_deaminase PF00962.22 KPI36786.1 - 7.1e-76 255.6 0.0 9.2e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KPI36786.1 - 0.02 14.2 0.0 4.3 6.5 0.0 2.2 1 1 1 2 2 2 0 Amidohydrolase family DHquinase_II PF01220.19 KPI36787.1 - 2.4e-57 192.4 0.0 2.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Abhydrolase_3 PF07859.13 KPI36788.1 - 1.5e-38 132.8 0.0 2.1e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI36788.1 - 1.4e-08 34.0 0.3 7.4e-08 31.7 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 KPI36788.1 - 0.00065 18.5 0.1 0.002 16.9 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KPI36788.1 - 0.0015 18.0 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KPI36788.1 - 0.015 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 KPI36788.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase LIAS_N PF16881.5 KPI36790.1 - 1.4e-25 89.8 0.0 3e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KPI36790.1 - 1.7e-14 54.5 0.0 2.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HMA PF00403.26 KPI36791.1 - 6.5e-16 58.5 0.2 7.9e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1677 PF07911.13 KPI36791.1 - 0.09 13.2 0.0 0.097 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Acyl_transf_3 PF01757.22 KPI36792.1 - 2.2e-33 115.8 32.3 3.2e-33 115.2 32.3 1.2 1 0 0 1 1 1 1 Acyltransferase family MFS_1 PF07690.16 KPI36793.1 - 1.8e-39 135.7 21.5 1.8e-39 135.7 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI36793.1 - 0.08 11.3 5.1 0.12 10.7 5.1 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MMR_HSR1_Xtn PF16897.5 KPI36797.1 - 1.4e-39 134.3 1.0 3.4e-39 133.1 0.3 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KPI36797.1 - 6.3e-23 80.6 0.1 1.3e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KPI36797.1 - 8e-21 74.3 0.1 3e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI36797.1 - 5.2e-09 35.8 0.0 2.5e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KPI36797.1 - 0.0014 18.2 0.1 8.3 5.9 0.0 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KPI36797.1 - 0.0017 18.5 0.1 0.36 10.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KPI36797.1 - 0.0038 16.2 0.2 0.017 14.1 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KPI36797.1 - 0.09 12.7 0.6 3.9 7.4 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase DHquinase_I PF01487.15 KPI36798.1 - 2.4e-19 70.5 0.0 4e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KPI36798.1 - 3.7e-17 62.3 0.1 1.1e-16 60.8 0.1 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KPI36798.1 - 1.1e-16 61.3 0.0 2.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KPI36798.1 - 1e-07 31.6 0.2 2.5e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KPI36798.1 - 3.1e-07 30.5 0.1 8.5e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_8 PF12780.7 KPI36798.1 - 0.06 12.7 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Fungal_trans PF04082.18 KPI36799.1 - 0.00022 20.3 0.1 0.00034 19.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPI36800.1 - 5.1e-72 243.2 19.5 6.1e-72 242.9 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36800.1 - 3.8e-18 65.5 24.1 3.8e-18 65.5 24.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sedlin_N PF04628.13 KPI36801.1 - 1.8e-10 41.1 0.0 2.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2293 PF10056.9 KPI36802.1 - 3.7e-28 97.6 0.0 1.2e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Papilin_u7 PF16626.5 KPI36802.1 - 0.65 10.6 5.6 12 6.6 0.7 2.7 2 0 0 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin Glyco_transf_90 PF05686.12 KPI36803.1 - 2.8e-20 72.6 1.5 9.8e-17 60.9 0.7 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Na_H_Exchanger PF00999.21 KPI36804.1 - 3.8e-57 193.8 19.8 4.9e-57 193.4 19.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Holin_BlyA PF05102.12 KPI36804.1 - 0.033 14.1 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 holin, BlyA family SelK_SelG PF10961.8 KPI36806.1 - 0.042 14.5 35.6 1.4e+03 -0.0 35.6 2.8 1 1 0 1 1 1 0 Selenoprotein SelK_SelG OPT PF03169.15 KPI36807.1 - 2.9e-85 287.1 24.7 3.3e-85 287.0 24.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AMP-binding PF00501.28 KPI36809.1 - 2.2e-23 82.6 0.1 8.9e-17 60.8 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme Sugar_tr PF00083.24 KPI36810.1 - 2e-82 277.5 12.9 2.4e-82 277.2 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36810.1 - 6.7e-14 51.6 45.3 3.6e-12 45.9 29.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI36810.1 - 0.094 11.6 9.1 0.023 13.6 1.1 2.3 2 0 0 2 2 2 0 MFS_1 like family Laminin_G_3 PF13385.6 KPI36812.1 - 0.00027 21.1 1.2 0.019 15.1 0.3 2.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily MG2 PF01835.19 KPI36812.1 - 0.016 15.7 0.0 4.9 7.7 0.0 2.5 2 0 0 2 2 2 0 MG2 domain Gly_transf_sug PF04488.15 KPI36813.1 - 2.8e-13 50.3 0.3 5.5e-13 49.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPI36813.1 - 0.065 12.6 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Sulfatase PF00884.23 KPI36814.1 - 9.4e-17 61.4 0.1 2e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPI36814.1 - 1.8e-05 24.5 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPI36814.1 - 0.011 14.4 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DBI_PRT PF02277.17 KPI36814.1 - 0.22 10.7 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyltransferase DUF3712 PF12505.8 KPI36815.1 - 3.2e-26 92.0 0.3 4e-25 88.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KPI36815.1 - 0.0049 17.4 0.4 0.43 11.1 0.1 2.4 2 0 0 2 2 2 1 Late embryogenesis abundant protein DUF1279 PF06916.13 KPI36815.1 - 0.086 13.4 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Glyco_hydro_16 PF00722.21 KPI36816.1 - 3.1e-08 33.3 1.1 3.3e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 TFIIA PF03153.13 KPI36816.1 - 2 8.3 17.7 2.5 8.0 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KPI36816.1 - 5.4 6.1 6.1 6.6 5.8 6.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lin-8 PF03353.15 KPI36816.1 - 6.2 6.3 8.2 9.2 5.7 8.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 KPI36816.1 - 7.4 4.7 11.8 8.6 4.5 11.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ldt_C PF17969.1 KPI36817.1 - 0.029 15.1 0.1 13 6.6 0.0 2.5 1 1 1 2 2 2 0 L,D-transpeptidase C-terminal domain Isochorismatase PF00857.20 KPI36818.1 - 1.8e-14 54.3 0.0 3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family TauD PF02668.16 KPI36819.1 - 2e-46 159.0 0.7 2.3e-46 158.8 0.7 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.25 KPI36820.1 - 3.1e-21 75.9 0.0 4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36820.1 - 3.3e-12 46.3 0.0 4.7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI36820.1 - 0.00012 22.0 0.0 0.0012 18.8 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KPI36820.1 - 0.17 11.2 0.8 0.28 10.5 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DGF-1_C PF11040.8 KPI36821.1 - 0.11 12.5 3.4 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TFIIE-A_C PF11521.8 KPI36821.1 - 0.12 12.6 0.9 0.56 10.5 0.9 2.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha AhpC-TSA PF00578.21 KPI36822.1 - 1.2e-25 89.8 0.0 1.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI36822.1 - 8.1e-19 67.8 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KPI36822.1 - 0.0012 18.9 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme MSP1_C PF07462.11 KPI36822.1 - 1.9 7.1 8.8 2.3 6.8 8.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus F-box-like PF12937.7 KPI36823.1 - 0.0028 17.5 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like PMBR PF09373.10 KPI36824.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Pseudomurein-binding repeat Cation_ATPase_C PF00689.21 KPI36825.1 - 1.3e-40 139.0 5.2 1.3e-40 139.0 5.2 3.1 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPI36825.1 - 7.1e-38 129.9 3.2 1.5e-37 128.9 0.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KPI36825.1 - 3.1e-20 73.4 0.0 4.7e-10 40.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPI36825.1 - 2.1e-16 59.8 0.0 5.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPI36825.1 - 2e-12 46.6 0.0 4.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI36825.1 - 7.2e-05 22.7 0.1 0.00014 21.7 0.0 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPI36825.1 - 0.025 15.0 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.24 KPI36825.1 - 0.67 9.7 6.8 0.92 9.3 0.0 3.3 3 0 0 3 3 3 0 Fatty acid desaturase bZIP_1 PF00170.21 KPI36828.1 - 0.00031 20.8 14.6 0.0011 19.0 13.3 2.1 1 1 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 KPI36828.1 - 0.021 15.4 0.2 0.021 15.4 0.2 1.7 2 0 0 2 2 2 0 SlyX bZIP_Maf PF03131.17 KPI36828.1 - 1.7 9.2 12.9 8 7.1 11.8 2.3 2 1 0 2 2 2 0 bZIP Maf transcription factor DUF3531 PF12049.8 KPI36829.1 - 0.11 12.4 0.3 0.33 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) UNC-93 PF05978.16 KPI36832.1 - 8.8e-14 51.5 5.1 8.8e-14 51.5 5.1 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KPI36832.1 - 7.6e-09 35.0 32.9 7.6e-09 35.0 32.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM40 PF15817.5 KPI36832.1 - 9.7 6.0 7.7 1 9.1 0.1 3.0 2 1 0 2 2 2 0 Transmembrane protein 40 family Zn_clus PF00172.18 KPI36833.1 - 3.1e-09 36.8 7.6 5.6e-09 36.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PXA PF02194.15 KPI36834.1 - 1.7e-44 152.0 1.9 5.9e-44 150.2 0.3 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KPI36834.1 - 0.0064 17.1 0.1 0.19 12.3 0.0 2.8 3 1 0 3 3 3 1 Sorting nexin C terminal Ribosomal_L31 PF01197.18 KPI36834.1 - 0.0078 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L31 Chon_Sulph_att PF06566.11 KPI36834.1 - 0.05 13.5 3.3 0.11 12.3 3.3 1.5 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Inositol_P PF00459.25 KPI36835.1 - 6.2e-77 258.8 0.0 7e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family COesterase PF00135.28 KPI36837.1 - 1.2e-81 275.1 0.0 6.3e-74 249.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI36837.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI36837.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.7 KPI36838.1 - 0.00043 20.1 0.1 0.17 11.8 0.0 2.9 2 1 0 2 2 2 2 F-box-like F-box PF00646.33 KPI36838.1 - 0.073 13.0 1.8 12 5.9 0.2 3.6 3 1 0 3 3 3 0 F-box domain F-box_4 PF15966.5 KPI36838.1 - 0.078 12.9 2.4 45 4.0 0.0 4.1 3 1 0 4 4 4 0 F-box Ribosomal_S3_C PF00189.20 KPI36839.1 - 1.1e-24 86.7 0.1 5.1e-24 84.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KPI36839.1 - 3.9e-12 45.8 0.1 6.4e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 KPI36839.1 - 0.0059 16.4 0.2 0.32 10.8 0.0 2.2 2 0 0 2 2 2 1 Coilin N-terminus UN_NPL4 PF11543.8 KPI36839.1 - 0.095 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DIOX_N PF14226.6 KPI36840.1 - 1.2e-17 64.7 0.0 2.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI36840.1 - 5.7e-15 55.6 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L13 PF00572.18 KPI36841.1 - 2.1e-11 44.1 0.4 2e-09 37.7 0.1 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 HET PF06985.11 KPI36843.1 - 7.3e-25 88.0 0.1 1e-24 87.5 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KIX_2 PF16987.5 KPI36844.1 - 1.7e-13 50.3 0.0 1.7e-13 50.3 0.0 4.3 3 1 1 4 4 4 1 KIX domain EloA-BP1 PF15870.5 KPI36844.1 - 5.3 7.3 11.1 0.11 12.8 2.4 2.4 2 2 0 2 2 2 0 ElonginA binding-protein 1 adh_short PF00106.25 KPI36846.1 - 1.1e-37 129.4 3.6 2e-37 128.5 3.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36846.1 - 2.7e-31 108.9 1.9 6.6e-31 107.7 1.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36846.1 - 3.4e-08 33.6 0.4 5.8e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI36846.1 - 4.5e-05 23.0 0.3 7.8e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI36846.1 - 0.00065 19.2 0.2 0.0012 18.3 0.2 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ABC_tran PF00005.27 KPI36847.1 - 6.6e-19 68.8 0.3 2.2e-16 60.6 0.3 2.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KPI36847.1 - 1.3e-05 25.1 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KPI36847.1 - 0.00024 21.4 0.9 0.00076 19.8 0.9 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KPI36847.1 - 0.00028 20.4 0.1 0.0016 17.9 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KPI36847.1 - 0.0012 19.4 0.1 0.0026 18.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI36847.1 - 0.0014 19.1 1.6 0.0014 19.1 1.6 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KPI36847.1 - 0.0015 18.7 0.9 0.0036 17.5 0.9 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPI36847.1 - 0.0018 18.6 1.5 0.011 16.0 1.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KPI36847.1 - 0.0026 18.3 6.1 0.0043 17.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KPI36847.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KPI36847.1 - 0.011 15.5 4.2 0.032 13.9 0.1 2.8 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KPI36847.1 - 0.017 15.0 0.1 0.047 13.6 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KPI36847.1 - 0.09 13.2 0.1 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KPI36847.1 - 0.14 11.8 0.4 0.38 10.4 0.0 1.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 KPI36847.1 - 0.32 9.6 3.5 0.23 10.1 0.6 2.0 2 1 0 2 2 2 0 AAA domain Ribosomal_L3 PF00297.22 KPI36849.1 - 6.7e-16 58.2 10.2 8.2e-14 51.4 6.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 ADH_zinc_N PF00107.26 KPI36850.1 - 4.2e-21 75.3 0.2 6.6e-21 74.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI36850.1 - 4.6e-14 53.6 0.0 8.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI36850.1 - 7.5e-07 29.0 0.0 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KPI36850.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 KPI36851.1 - 1.3e-23 83.8 0.0 1.9e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI36851.1 - 0.00043 20.2 0.0 0.0075 16.2 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPI36851.1 - 0.0037 17.2 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI36851.1 - 0.011 15.2 0.1 0.068 12.6 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPI36851.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4327 PF14217.6 KPI36851.1 - 0.2 11.8 0.2 0.35 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) PGM_PMM_III PF02880.16 KPI36852.1 - 2.8e-11 43.6 0.0 6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KPI36852.1 - 9.5e-09 35.8 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KPI36852.1 - 1.1e-07 32.0 0.0 6.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 KPI36852.1 - 3.4e-06 26.8 0.0 1.2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YchF-GTPase_C PF06071.13 KPI36853.1 - 1.6e-33 114.8 0.2 4e-33 113.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KPI36853.1 - 1.9e-16 60.2 0.0 5.9e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI36853.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KPI36853.1 - 0.0051 16.8 0.1 0.015 15.3 0.1 1.8 1 0 0 1 1 1 1 TGS domain AAA_23 PF13476.6 KPI36853.1 - 1.3 9.5 4.2 7 7.1 4.2 2.1 1 1 0 1 1 1 0 AAA domain Beta-lactamase PF00144.24 KPI36854.1 - 9.4e-20 71.1 1.5 2.8e-19 69.6 1.5 1.6 1 1 0 1 1 1 1 Beta-lactamase Transp_cyt_pur PF02133.15 KPI36855.1 - 9e-89 298.2 34.5 1e-88 298.0 34.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin tRNA_synthFbeta PF17759.1 KPI36857.1 - 4.2e-37 127.7 0.0 6.4e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KPI36857.1 - 9e-31 105.9 0.2 8e-30 102.9 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KPI36857.1 - 7.5e-26 90.9 0.0 1.3e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KPI36857.1 - 1.3e-18 67.0 0.0 2.4e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain LMBR1 PF04791.16 KPI36858.1 - 2.9e-112 376.2 8.1 3.3e-112 376.0 8.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein UPF0242 PF06785.11 KPI36858.1 - 0.025 14.7 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UL41A PF17591.2 KPI36858.1 - 0.025 14.7 0.1 0.093 12.8 0.1 2.0 1 1 0 1 1 1 0 Herpesvirus UL41A Glyco_H_20C_C PF18088.1 KPI36858.1 - 0.18 11.7 0.6 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain DUF3675 PF12428.8 KPI36858.1 - 0.62 10.6 5.8 1.3 9.6 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Cep3 PF16846.5 KPI36859.1 - 4.1e-05 22.3 0.0 6.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B WD40 PF00400.32 KPI36860.1 - 8.3e-13 48.6 6.2 0.0036 18.1 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI36860.1 - 7e-05 23.1 0.5 1.1 9.6 0.0 4.0 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KPI36860.1 - 0.00069 18.1 0.6 0.00098 17.6 0.0 1.4 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KPI36860.1 - 0.0038 16.0 0.3 0.025 13.3 0.3 2.2 1 1 0 1 1 1 1 Nup133 N terminal like IFP_35_N PF07334.13 KPI36860.1 - 0.95 9.6 2.7 2.7 8.1 1.9 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus adh_short PF00106.25 KPI36861.1 - 2e-42 144.9 0.8 4.3e-42 143.8 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36861.1 - 1.2e-40 139.5 0.2 4.2e-39 134.5 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36861.1 - 1.4e-08 34.8 4.7 3e-08 33.8 0.1 2.2 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 KPI36861.1 - 0.0013 18.1 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.16 KPI36861.1 - 0.0079 15.8 0.2 0.035 13.8 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KPI36861.1 - 0.0088 16.6 0.3 0.023 15.2 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI36861.1 - 0.052 12.8 0.8 0.085 12.1 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain DUF5636 PF18686.1 KPI36861.1 - 0.061 13.5 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5636) Polysacc_synt_2 PF02719.15 KPI36861.1 - 0.065 12.4 0.2 0.12 11.5 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI36861.1 - 0.073 12.5 0.2 0.49 9.8 0.0 2.0 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KPI36861.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KPI36861.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KPI36861.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OPT PF03169.15 KPI36864.1 - 4.5e-62 210.6 17.2 5.1e-62 210.4 17.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PIN_4 PF13638.6 KPI36864.1 - 0.015 15.6 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 PIN domain FMO-like PF00743.19 KPI36866.1 - 9.3e-12 44.1 0.0 4.4e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI36866.1 - 1.9e-09 37.6 0.9 4e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI36866.1 - 2.4e-06 26.9 0.2 0.013 14.7 0.1 3.3 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI36866.1 - 4.5e-05 22.8 0.0 0.00033 20.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI36866.1 - 0.00046 19.5 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KPI36866.1 - 0.0031 17.1 0.0 0.23 11.0 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI36866.1 - 0.0049 16.9 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI36866.1 - 0.019 14.2 0.0 0.27 10.4 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI36866.1 - 0.16 11.2 0.2 0.34 10.1 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KPI36866.1 - 0.21 12.2 0.2 7.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 KPI36867.1 - 1.5e-11 44.9 0.0 4.8e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KPI36867.1 - 4.4e-06 26.7 0.3 5.1e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI36867.1 - 2.7e-05 23.7 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KPI36867.1 - 0.12 12.6 0.5 1.3 9.3 0.5 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Fungal_trans_2 PF11951.8 KPI36868.1 - 0.014 14.3 0.4 0.062 12.1 0.4 2.1 1 1 0 1 1 1 0 Fungal specific transcription factor domain Methyltransf_2 PF00891.18 KPI36869.1 - 5.7e-21 74.8 0.0 4.8e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KPI36869.1 - 0.00025 21.7 0.0 0.00071 20.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI36869.1 - 0.04 14.7 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain cobW PF02492.19 KPI36869.1 - 0.077 12.6 0.2 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF745 PF05335.13 KPI36869.1 - 2.3 7.9 8.4 0.93 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Cu_bind_like PF02298.17 KPI36870.1 - 0.014 15.4 0.1 0.041 13.9 0.1 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain CDO_I PF05995.12 KPI36871.1 - 1.7e-39 134.8 0.0 2.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KPI36871.1 - 7.9e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO GFA PF04828.14 KPI36873.1 - 1.2e-18 67.2 0.4 1.9e-18 66.6 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 KPI36873.1 - 0.31 11.3 3.1 0.4 11.0 0.1 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase PF00069.25 KPI36874.1 - 4.1e-05 23.1 0.0 7.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Acetyltransf_1 PF00583.25 KPI36875.1 - 5.5e-11 42.7 0.0 6.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI36875.1 - 8.1e-09 35.8 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI36875.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI36875.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPI36875.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KPI36875.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPI36875.1 - 0.0015 19.2 0.0 0.0017 19.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KPI36875.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KPI36875.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KPI36875.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Redoxin PF08534.10 KPI36876.1 - 2.4e-23 82.5 0.0 2.7e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KPI36876.1 - 1.1e-08 35.0 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Transp_cyt_pur PF02133.15 KPI36877.1 - 1.7e-87 294.1 37.8 2.1e-87 293.8 37.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bromodomain PF00439.25 KPI36878.1 - 2.4e-37 126.9 3.3 1.6e-19 69.7 0.7 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KPI36878.1 - 5.1e-15 55.4 0.6 1.2e-14 54.2 0.6 1.7 1 0 0 1 1 1 1 BAH domain AT_hook PF02178.19 KPI36878.1 - 4.1 7.6 8.6 13 6.0 1.6 3.5 2 0 0 2 2 2 0 AT hook motif Glyco_transf_15 PF01793.16 KPI36879.1 - 1.9e-70 237.7 0.0 2.3e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase adh_short PF00106.25 KPI36883.1 - 8e-34 116.8 0.1 2.3e-17 63.1 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36883.1 - 2.4e-26 92.7 1.0 1.5e-13 50.9 0.1 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36883.1 - 1.2e-06 28.6 0.1 0.002 18.1 0.0 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KPI36883.1 - 2.2e-05 24.1 0.0 0.00011 21.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KPI36883.1 - 0.0029 18.3 0.5 0.0075 16.9 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI36883.1 - 0.018 15.7 0.1 0.17 12.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KPI36883.1 - 0.11 11.8 0.1 0.61 9.4 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 KPI36883.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 KPI36884.1 - 2.6e-33 115.1 0.0 6.9e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36884.1 - 5.1e-25 88.4 0.2 4.5e-24 85.3 0.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36884.1 - 1.4e-07 31.6 0.1 6.1e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KPI36884.1 - 0.028 13.9 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Plasmodium_Vir PF05795.11 KPI36885.1 - 0.0072 15.8 5.2 0.011 15.2 5.2 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein PA26 PF04636.13 KPI36885.1 - 0.11 11.4 8.0 0.15 11.0 8.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CAF-1_p150 PF11600.8 KPI36885.1 - 0.17 11.6 37.2 0.34 10.6 37.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SARAF PF06682.12 KPI36885.1 - 0.69 9.5 10.5 0.43 10.2 6.6 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Borrelia_P83 PF05262.11 KPI36885.1 - 0.98 7.8 14.9 1.7 7.0 14.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF3_subunit PF08597.10 KPI36885.1 - 3.4 7.5 27.0 5.1 6.9 27.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Phosducin PF02114.16 KPI36885.1 - 8.4 5.3 11.6 13 4.6 11.6 1.2 1 0 0 1 1 1 0 Phosducin Sugar_tr PF00083.24 KPI36888.1 - 4.3e-65 220.3 9.0 7.2e-65 219.6 8.7 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI36888.1 - 4.3e-27 95.0 21.3 5.6e-27 94.6 21.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI36888.1 - 0.041 12.3 4.5 0.027 12.9 2.2 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.12 KPI36888.1 - 0.079 12.4 8.5 0.038 13.4 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF554) Holin_BhlA PF10960.8 KPI36888.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 BhlA holin family STE3 PF02076.15 KPI36889.1 - 3.5e-33 115.1 15.5 5e-33 114.5 15.5 1.2 1 0 0 1 1 1 1 Pheromone A receptor Sugar_tr PF00083.24 KPI36890.1 - 4e-92 309.4 27.6 1.7e-53 182.1 11.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI36890.1 - 4.1e-20 72.0 37.9 4.7e-15 55.4 11.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KPI36890.1 - 4.1 5.6 7.6 9.6 4.4 7.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5315 PF17242.2 KPI36891.1 - 9.5e-22 76.6 3.3 9.5e-22 76.6 3.3 2.1 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) WHIM1 PF15612.6 KPI36892.1 - 4.6e-05 22.8 0.0 0.00011 21.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.12 KPI36892.1 - 1.5 7.0 10.5 2.6 6.2 10.5 1.3 1 0 0 1 1 1 0 Nop14-like family CTP_transf_like PF01467.26 KPI36894.1 - 3.8e-27 95.2 0.0 8e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like NUP50 PF08911.11 KPI36895.1 - 0.014 16.0 2.3 0.014 16.0 2.3 3.8 4 1 0 4 4 4 0 NUP50 (Nucleoporin 50 kDa) Sec2p PF06428.11 KPI36895.1 - 0.47 10.5 20.9 4.2 7.4 9.1 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p AAA_13 PF13166.6 KPI36895.1 - 0.92 8.1 16.2 1.4 7.4 16.2 1.2 1 0 0 1 1 1 0 AAA domain MIOX PF05153.15 KPI36896.1 - 7.6e-92 307.4 0.1 1.1e-91 306.9 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase UBD PF16455.5 KPI36896.1 - 0.021 15.0 0.1 0.037 14.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain HD PF01966.22 KPI36896.1 - 0.024 14.9 0.1 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 HD domain DUF1796 PF08795.10 KPI36896.1 - 0.091 12.7 0.5 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Elong_Iki1 PF10483.9 KPI36897.1 - 7.8e-88 294.8 0.0 9.1e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 WD40 PF00400.32 KPI36898.1 - 4.2e-17 62.2 2.5 0.012 16.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI36898.1 - 6.5e-08 32.8 0.0 0.055 13.8 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI36898.1 - 0.00034 19.7 0.4 0.69 8.8 0.0 4.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Acetyltransf_10 PF13673.7 KPI36899.1 - 3.6e-09 36.6 0.0 7.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI36899.1 - 6.1e-09 36.1 0.0 9.4e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI36899.1 - 1e-07 32.3 0.2 2e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4936 PF16290.5 KPI36899.1 - 0.019 15.7 1.6 0.55 10.9 0.2 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4936) FR47 PF08445.10 KPI36899.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 KPI36899.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans PF04082.18 KPI36900.1 - 6.4e-14 51.6 0.3 1.7e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPI36900.1 - 3.6e-11 42.9 7.2 4.7e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI36900.1 - 1.8e-09 37.6 1.7 1.8e-09 37.6 1.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI36900.1 - 1.1e-08 35.2 6.9 0.0023 18.6 2.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI36900.1 - 4.7e-05 23.5 0.1 0.61 10.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KPI36900.1 - 0.00094 19.4 2.9 0.002 18.4 2.9 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KPI36900.1 - 0.007 16.2 3.7 1.7 8.7 1.3 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.7 KPI36900.1 - 0.092 13.2 0.5 10 6.6 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 KPI36900.1 - 0.22 11.5 0.9 0.6 10.1 0.4 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KPI36900.1 - 1.8 8.4 6.1 2.4 8.0 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KPI36900.1 - 2.5 8.6 5.9 2.4 8.7 2.1 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KPI36900.1 - 6.3 6.5 8.3 1 9.1 1.6 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DHDPS PF00701.22 KPI36901.1 - 7.7e-36 123.3 0.0 8.6e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Radical_SAM PF04055.21 KPI36901.1 - 0.079 13.3 0.0 22 5.4 0.0 2.9 3 0 0 3 3 3 0 Radical SAM superfamily Pdase_C33_assoc PF14756.6 KPI36901.1 - 0.083 12.8 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase_C33-associated domain MFS_1 PF07690.16 KPI36902.1 - 9.2e-32 110.3 28.0 9.2e-32 110.3 28.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Halogen_Hydrol PF10112.9 KPI36902.1 - 0.068 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4419 PF14388.6 KPI36903.1 - 0.051 13.0 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) Septin PF00735.18 KPI36904.1 - 6.5e-107 357.0 0.1 1.4e-106 355.9 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KPI36904.1 - 2.5e-05 24.3 0.0 6.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI36904.1 - 0.00064 19.3 0.2 0.054 13.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KPI36904.1 - 0.00079 19.5 4.3 0.44 10.6 0.0 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KPI36904.1 - 0.0014 18.6 3.4 0.0032 17.4 0.2 2.8 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KPI36904.1 - 0.013 14.8 0.1 0.039 13.3 0.1 1.8 1 1 0 1 1 1 0 AIG1 family GBP_C PF02841.14 KPI36904.1 - 0.068 12.6 8.3 0.094 12.1 8.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FtsK_SpoIIIE PF01580.18 KPI36904.1 - 0.07 12.5 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KPI36904.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KPI36904.1 - 0.27 11.5 2.6 0.37 11.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain EB1 PF03271.17 KPI36904.1 - 0.48 10.7 4.3 5.7 7.3 1.1 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif YIF1 PF03878.15 KPI36906.1 - 4e-95 317.9 4.5 4.8e-95 317.6 4.5 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KPI36906.1 - 0.0003 20.5 4.7 0.0003 20.5 4.7 1.9 2 0 0 2 2 2 1 Yip1 domain tRNA-synt_1e PF01406.19 KPI36907.1 - 2.9e-106 355.2 0.3 3.8e-106 354.8 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KPI36907.1 - 0.00067 18.5 1.4 0.54 8.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Sod_Cu PF00080.20 KPI36908.1 - 2.4e-46 157.4 6.2 2.7e-46 157.2 6.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BppL_N PF18338.1 KPI36908.1 - 3.7 7.5 6.7 6.8 6.6 0.1 3.4 3 0 0 3 3 3 0 Lower baseplate protein N-terminal domain His_Phos_2 PF00328.22 KPI36909.1 - 8.4e-42 143.9 0.0 1.8e-36 126.3 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 KPI36910.1 - 3e-40 137.8 0.0 4.8e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36910.1 - 7.1e-31 107.6 0.0 7.1e-31 107.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36910.1 - 0.00035 20.5 1.9 0.02 14.8 0.0 2.9 3 0 0 3 3 3 1 KR domain NAD_binding_1 PF00175.21 KPI36910.1 - 0.0089 16.7 0.0 0.14 12.8 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain 3HCDH_N PF02737.18 KPI36910.1 - 0.029 14.2 0.1 0.029 14.2 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPI36910.1 - 0.036 14.3 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KPI36910.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_6 PF08030.12 KPI36910.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain SNF2_N PF00176.23 KPI36911.1 - 9.6e-23 80.4 0.0 9.6e-23 80.4 0.0 2.8 3 2 1 4 4 4 1 SNF2 family N-terminal domain HSA PF07529.13 KPI36911.1 - 3.1e-17 62.7 12.3 3.1e-17 62.7 12.3 4.2 4 1 1 5 5 5 1 HSA QLQ PF08880.11 KPI36911.1 - 1.7e-11 43.7 0.7 1.7e-11 43.7 0.7 2.8 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KPI36911.1 - 7.7e-06 26.0 0.0 7.7e-06 26.0 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Exo_endo_phos PF03372.23 KPI36912.1 - 1e-09 38.3 0.0 1.8e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Longin PF13774.6 KPI36913.1 - 8.5e-28 96.2 0.6 1.4e-27 95.5 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KPI36913.1 - 1.1e-14 53.9 0.1 3.3e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.12 KPI36913.1 - 0.041 13.9 1.6 1.3 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SLM4 PF16818.5 KPI36913.1 - 0.074 13.0 1.6 0.53 10.2 0.0 2.2 1 1 0 2 2 2 0 Protein SLM4 BTB PF00651.31 KPI36916.1 - 3.3e-13 49.8 0.9 1.1e-12 48.1 0.2 2.0 1 1 0 2 2 2 1 BTB/POZ domain PhaC_N PF07167.13 KPI36916.1 - 0.045 13.4 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus NUDIX PF00293.28 KPI36918.1 - 2.1e-19 69.8 0.4 2.5e-19 69.6 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KPI36918.1 - 0.041 13.9 0.0 0.077 13.0 0.0 1.5 1 1 0 1 1 1 0 NUDIX domain Acetyltransf_1 PF00583.25 KPI36919.1 - 8.6e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI36919.1 - 2.6e-06 27.7 0.0 4.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI36919.1 - 1.6e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SNF5 PF04855.12 KPI36920.1 - 1.2e-71 241.2 0.0 2.4e-71 240.3 0.0 1.4 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KPI36920.1 - 8.3e-06 25.3 2.7 9.5e-06 25.1 1.4 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF2439 PF10382.9 KPI36922.1 - 8.3e-17 61.3 0.1 1.4e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) HET PF06985.11 KPI36923.1 - 1.3e-23 83.9 1.4 9.4e-23 81.2 1.4 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spectrin_like PF18373.1 KPI36925.1 - 0.018 15.1 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Spectrin like domain Exo_endo_phos PF03372.23 KPI36926.1 - 3.3e-06 26.8 0.0 9.4e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IRF PF00605.17 KPI36926.1 - 0.056 13.7 0.3 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor CDH-cyt PF16010.5 KPI36927.1 - 1.7e-26 93.0 0.0 3.3e-18 66.0 0.0 2.3 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase Cupin_2 PF07883.11 KPI36927.1 - 1.3e-10 40.8 1.0 2.7e-10 39.8 1.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KPI36927.1 - 8.3e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KPI36927.1 - 0.033 14.1 0.2 0.051 13.5 0.2 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase EutQ PF06249.12 KPI36927.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Helicase_C PF00271.31 KPI36928.1 - 3.4e-19 69.2 0.0 8.5e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KPI36928.1 - 2.2e-17 62.9 0.0 5.2e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 KPI36928.1 - 7.9e-14 52.0 2.6 7.9e-14 52.0 2.6 2.8 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex SNF2_N PF00176.23 KPI36928.1 - 9.5e-12 44.3 0.4 1.5e-11 43.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 KPI36928.1 - 0.0005 19.3 0.0 0.0019 17.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Trypan_PARP PF05887.11 KPI36928.1 - 0.0088 16.0 11.8 0.0088 16.0 11.8 3.2 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) MOZART1 PF12554.8 KPI36930.1 - 1e-21 76.4 1.8 1.3e-21 76.1 1.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DHHA1 PF02272.19 KPI36930.1 - 0.026 14.9 0.2 0.026 14.9 0.2 1.6 1 1 1 2 2 2 0 DHHA1 domain SRP-alpha_N PF04086.13 KPI36931.1 - 3.5e-68 230.7 0.0 4.8e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KPI36931.1 - 3.1e-50 170.5 1.5 3.8e-50 170.3 0.4 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KPI36931.1 - 1.8e-07 30.4 0.0 3.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 KPI36931.1 - 8.7e-06 25.9 0.2 3.5e-05 23.9 0.0 2.1 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KPI36931.1 - 0.0012 18.6 0.2 0.0037 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KPI36931.1 - 0.0028 17.7 0.1 0.0088 16.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KPI36931.1 - 0.0028 18.1 0.2 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KPI36931.1 - 0.0073 16.4 0.8 0.28 11.3 0.1 2.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KPI36931.1 - 0.023 14.6 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_31 PF13614.6 KPI36931.1 - 0.03 14.3 0.1 0.34 10.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KPI36931.1 - 0.063 13.8 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ArsA_ATPase PF02374.15 KPI36931.1 - 0.071 12.3 0.0 9.5 5.3 0.0 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_33 PF13671.6 KPI36931.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Tad PF13400.6 KPI36932.1 - 0.55 10.6 7.9 1 9.7 7.9 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF5427 PF10310.9 KPI36932.1 - 1.1 8.1 3.8 1.7 7.5 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Lactamase_B PF00753.27 KPI36933.1 - 3e-09 37.2 0.0 7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3425 PF11905.8 KPI36934.1 - 1.2e-05 25.2 0.2 2.4e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI36934.1 - 0.023 14.8 5.1 0.057 13.5 5.0 1.7 1 1 0 1 1 1 0 bZIP transcription factor LUC7 PF03194.15 KPI36934.1 - 0.048 13.3 0.8 0.07 12.8 0.8 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Metal_resist PF13801.6 KPI36934.1 - 0.12 12.5 5.0 0.49 10.6 5.0 2.1 1 0 0 1 1 1 0 Heavy-metal resistance Nop53 PF07767.11 KPI36934.1 - 0.36 10.2 9.0 0.51 9.7 9.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BAR PF03114.18 KPI36935.1 - 2.9e-49 167.9 10.9 3.5e-49 167.6 10.9 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KPI36935.1 - 2.5e-06 26.8 8.0 4.1e-06 26.2 8.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OmpH PF03938.14 KPI36935.1 - 0.0078 16.6 16.6 0.23 11.8 9.9 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) DUF2018 PF09442.10 KPI36935.1 - 0.065 14.2 2.6 1.4 9.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) APG6_N PF17675.1 KPI36935.1 - 0.072 13.6 10.7 0.074 13.6 9.2 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Mer2 PF09074.10 KPI36935.1 - 0.77 9.5 7.7 0.84 9.4 1.7 2.1 2 0 0 2 2 2 0 Mer2 HAUS6_N PF14661.6 KPI36935.1 - 3.2 7.3 9.8 0.32 10.6 3.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 KPI36935.1 - 9.6 5.7 10.1 23 4.4 10.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Mso1_Sec1_bdg PF14475.6 KPI36937.1 - 2.1e-12 46.4 0.1 4.4e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ammonium_transp PF00909.21 KPI36938.1 - 1.9e-56 191.5 25.1 9.7e-45 152.9 19.8 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Sulfatase PF00884.23 KPI36939.1 - 1e-63 215.6 1.3 1.2e-63 215.4 1.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPI36939.1 - 0.0014 18.3 0.1 0.0061 16.2 0.1 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KPI36939.1 - 0.054 12.1 0.0 0.16 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF229) FMO-like PF00743.19 KPI36940.1 - 5.1e-14 51.6 0.9 1.3e-13 50.2 0.1 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI36940.1 - 1.6e-10 40.6 0.1 2.5e-08 33.4 0.1 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI36940.1 - 3.9e-10 39.8 0.0 1.3e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI36940.1 - 1.6e-08 34.1 0.0 6.1e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI36940.1 - 1.8e-08 34.0 0.1 1.8e-07 30.7 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI36940.1 - 1.4e-05 24.9 0.9 0.091 12.3 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Mqo PF06039.15 KPI36940.1 - 0.0036 15.9 0.1 0.86 8.1 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KPI36940.1 - 0.0048 16.9 0.2 0.17 11.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KPI36940.1 - 0.027 13.7 0.1 0.074 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.32 KPI36941.1 - 0.00017 22.3 2.1 1 10.3 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Na_H_Exchanger PF00999.21 KPI36942.1 - 6.2e-72 242.5 37.1 7.6e-72 242.2 37.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NiFe_hyd_3_EhaA PF17367.2 KPI36942.1 - 1.3 9.2 12.6 1.5 9.0 0.6 3.8 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A Aldo_ket_red PF00248.21 KPI36943.1 - 3.6e-38 131.4 0.0 7.1e-31 107.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family GFA PF04828.14 KPI36944.1 - 5.4e-05 23.5 1.3 6.7e-05 23.1 1.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_25 PF13649.6 KPI36945.1 - 1.3e-08 35.4 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI36945.1 - 2.5e-08 34.6 0.0 4.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI36945.1 - 7.8e-07 29.0 0.0 2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI36945.1 - 3.3e-06 27.0 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI36945.1 - 0.00097 19.7 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPI36945.1 - 0.028 14.5 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KPI36945.1 - 0.065 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KPI36945.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FR47 PF08445.10 KPI36946.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein SNRNP27 PF08648.12 KPI36947.1 - 1.3e-26 92.4 1.3 2.9e-26 91.3 1.3 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Trypan_PARP PF05887.11 KPI36947.1 - 2 8.4 12.4 1.1 9.3 6.3 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) MitMem_reg PF13012.6 KPI36948.1 - 8.6e-08 32.6 1.3 2.4e-07 31.1 1.3 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KPI36948.1 - 1.7e-07 31.2 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4638 PF15472.6 KPI36948.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) bZIP_1 PF00170.21 KPI36949.1 - 3.7e-08 33.3 10.1 5.4e-08 32.8 10.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.18 KPI36949.1 - 0.056 13.7 1.4 0.1 12.8 1.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 KPI36949.1 - 0.12 12.2 3.8 0.12 12.2 2.8 1.4 1 1 0 1 1 1 0 Septum formation initiator DUF2514 PF10721.9 KPI36949.1 - 0.12 12.4 5.3 0.19 11.8 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GCN5L1 PF06320.13 KPI36949.1 - 0.19 11.9 5.2 0.28 11.4 5.2 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) bZIP_Maf PF03131.17 KPI36949.1 - 0.55 10.8 13.8 1.1 9.8 13.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KPI36949.1 - 0.72 10.0 19.9 4.9 7.3 10.8 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KPI36949.1 - 1.3 9.1 12.1 0.13 12.3 7.9 1.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TBCC_N PF16752.5 KPI36949.1 - 3.2 8.2 9.7 0.27 11.7 5.0 1.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain ERG2_Sigma1R PF04622.12 KPI36950.1 - 3e-86 288.1 0.1 3.3e-86 287.9 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein 53-BP1_Tudor PF09038.10 KPI36950.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Fungal_trans PF04082.18 KPI36952.1 - 4.1e-10 39.1 0.6 1.8e-09 37.1 0.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box-like_2 PF13013.6 KPI36954.1 - 0.058 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain MFS_1 PF07690.16 KPI36955.1 - 3.1e-25 88.8 28.3 4.6e-25 88.3 28.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI36955.1 - 5.2e-19 68.4 21.9 7.6e-19 67.9 21.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.9 KPI36955.1 - 0.0072 16.5 0.5 0.018 15.2 0.2 1.8 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Amastin PF07344.11 KPI36955.1 - 0.23 11.3 6.0 0.22 11.4 0.2 2.4 1 1 0 2 2 2 0 Amastin surface glycoprotein RhodobacterPufX PF11511.8 KPI36955.1 - 0.76 9.4 6.9 3.5 7.3 0.1 3.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX WD40 PF00400.32 KPI36956.1 - 3.3e-21 75.2 22.7 1.1e-05 26.1 0.5 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI36956.1 - 2.3e-08 34.2 5.8 0.018 15.4 0.0 4.6 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L2_C PF03947.18 KPI36957.1 - 4.1e-41 140.1 7.0 5.9e-41 139.6 5.5 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KPI36957.1 - 6.9e-16 58.0 0.1 2.8e-15 56.0 0.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PP2C PF00481.21 KPI36958.1 - 2.1e-82 276.7 0.3 3.4e-82 275.9 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C DCP1 PF06058.13 KPI36959.1 - 1.1e-20 73.7 0.0 1.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family GSH_synth_ATP PF03917.17 KPI36960.1 - 4.9e-117 390.9 0.0 3.8e-115 384.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KPI36960.1 - 4.1e-28 97.9 0.0 7.3e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase RPN13_C PF16550.5 KPI36960.1 - 0.16 12.1 1.6 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 UCH-binding domain Clr5 PF14420.6 KPI36961.1 - 7.7e-16 58.1 0.3 2.9e-15 56.2 0.3 2.1 2 0 0 2 2 2 1 Clr5 domain PhnI PF05861.12 KPI36961.1 - 0.0092 14.9 0.2 0.0092 14.9 0.2 1.6 2 0 0 2 2 2 1 Bacterial phosphonate metabolism protein (PhnI) SWIRM-assoc_2 PF16496.5 KPI36963.1 - 0.52 9.1 10.0 0.82 8.5 10.0 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PhoLip_ATPase_C PF16212.5 KPI36964.1 - 6.2e-79 265.3 24.3 6.2e-79 265.3 24.3 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPI36964.1 - 6.1e-21 73.9 2.2 1.8e-20 72.4 2.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KPI36964.1 - 5.6e-10 39.2 0.0 2.3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPI36964.1 - 1.3e-09 38.6 1.8 8.7e-06 26.2 0.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPI36964.1 - 0.00043 19.9 0.0 0.02 14.4 0.0 3.1 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KPI36964.1 - 0.015 15.1 0.3 0.034 13.9 0.3 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KPI36965.1 - 1.2e-28 100.1 26.2 2.4e-28 99.1 24.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RRXRR PF14239.6 KPI36965.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RRXRR protein SSB PF00436.25 KPI36966.1 - 7.1e-17 61.3 0.0 8.8e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PilX PF13681.6 KPI36966.1 - 0.015 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term Zn_clus PF00172.18 KPI36967.1 - 9.1e-08 32.1 7.5 1.4e-07 31.5 7.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.6 KPI36968.1 - 2.7e-21 76.4 0.0 3.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI36968.1 - 1.1e-07 32.3 0.3 5.7e-07 30.0 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI36968.1 - 8.8e-07 28.9 0.1 2.6e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like LIDHydrolase PF10230.9 KPI36969.1 - 3.4e-50 171.1 0.0 5.9e-50 170.3 0.0 1.4 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KPI36969.1 - 2e-07 31.9 0.5 1.4e-06 29.1 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI36969.1 - 0.00025 20.8 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KPI36969.1 - 0.0037 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF3640 PF12342.8 KPI36969.1 - 0.16 11.7 1.5 0.41 10.4 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) DMPK_coil PF08826.10 KPI36971.1 - 0.0066 16.5 0.3 0.022 14.9 0.3 1.9 1 0 0 1 1 1 1 DMPK coiled coil domain like PRKG1_interact PF15898.5 KPI36971.1 - 0.012 16.5 0.6 0.047 14.6 0.6 2.0 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 KPI36971.1 - 0.098 12.8 0.8 0.25 11.4 0.8 1.7 1 0 0 1 1 1 0 Basic region leucine zipper YabA PF06156.13 KPI36971.1 - 0.14 12.9 1.7 2.6 8.7 0.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF4521 PF15021.6 KPI36971.1 - 5 7.0 9.6 14 5.6 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4521) SEN1_N PF12726.7 KPI36972.1 - 3.2e-172 574.5 17.8 4.2e-172 574.2 17.8 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KPI36972.1 - 2e-71 240.9 3.7 2e-71 240.9 3.7 2.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KPI36972.1 - 5.9e-60 202.3 0.0 1.4e-59 201.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI36972.1 - 1.9e-09 37.5 0.5 7.4e-06 25.8 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPI36972.1 - 2.9e-08 34.2 0.0 8.9e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPI36972.1 - 1.7e-06 28.0 0.4 0.0045 16.8 0.1 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KPI36972.1 - 0.00022 21.8 0.6 0.00022 21.8 0.6 3.0 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KPI36972.1 - 0.0039 16.3 0.0 0.0086 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 KPI36972.1 - 0.018 14.8 0.8 0.095 12.5 0.1 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase RuvB_N PF05496.12 KPI36972.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Helicase_RecD PF05127.14 KPI36972.1 - 0.077 12.8 0.8 4.7 7.0 0.1 3.1 2 1 1 3 3 3 0 Helicase AAA_29 PF13555.6 KPI36972.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KPI36972.1 - 3.9 7.8 5.4 2.1 8.7 0.0 3.4 4 0 0 4 4 3 0 AAA ATPase domain SNF2_N PF00176.23 KPI36973.1 - 1.2e-57 195.2 0.0 2.4e-57 194.3 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI36973.1 - 4.2e-13 49.6 0.0 9.5e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KPI36973.1 - 9.1e-10 38.2 6.0 1.6e-09 37.4 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KPI36973.1 - 6.4e-07 29.3 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 KPI36973.1 - 1.8e-06 27.7 9.9 4.8e-06 26.3 9.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KPI36973.1 - 2.4e-06 27.7 0.0 6.8e-06 26.2 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KPI36973.1 - 5.5e-06 26.1 8.9 1.2e-05 25.0 8.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KPI36973.1 - 1.2e-05 25.1 9.3 2.7e-05 23.9 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPI36973.1 - 1.3e-05 25.2 9.9 2.4e-05 24.4 9.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KPI36973.1 - 1.5e-05 24.9 5.4 3.1e-05 23.9 5.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPI36973.1 - 7.2e-05 23.0 9.3 0.00017 21.9 9.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPI36973.1 - 0.0018 18.2 7.4 0.0047 16.9 7.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain AAA_34 PF13872.6 KPI36973.1 - 0.0027 16.6 0.0 0.005 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_4 PF14570.6 KPI36973.1 - 0.0055 16.5 8.1 0.011 15.5 8.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 KPI36973.1 - 0.06 13.8 1.9 0.15 12.5 1.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-BED PF02892.15 KPI36973.1 - 0.17 11.9 0.4 0.61 10.1 0.2 2.0 2 0 0 2 2 2 0 BED zinc finger CDC45 PF02724.14 KPI36973.1 - 0.44 8.8 5.6 0.9 7.7 5.6 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF5339 PF17274.2 KPI36973.1 - 9.9 7.1 6.5 25 5.8 0.1 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Ribosom_S12_S23 PF00164.25 KPI36974.1 - 2.3e-48 162.5 0.9 2.6e-48 162.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DAO PF01266.24 KPI36975.1 - 9.9e-37 127.3 0.0 1.2e-36 127.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI36975.1 - 1.5e-05 25.1 0.3 5.3e-05 23.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KPI36975.1 - 0.00025 20.0 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 MCRA family Glyco_hydro_114 PF03537.13 KPI36975.1 - 0.09 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Pkinase PF00069.25 KPI36976.1 - 4.3e-67 226.3 0.0 8.6e-67 225.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36976.1 - 7.3e-48 163.1 0.0 2.9e-47 161.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KPI36976.1 - 4.9e-28 97.4 0.4 2.3e-27 95.3 0.1 2.1 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KPI36976.1 - 1.3e-15 57.6 0.0 2.6e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KPI36976.1 - 2.5e-14 53.1 0.1 5.7e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KPI36976.1 - 1.5e-05 24.5 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like RA PF00788.23 KPI36976.1 - 0.0079 16.8 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KPI36976.1 - 0.0084 14.9 0.6 0.039 12.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase SAM_4 PF18017.1 KPI36976.1 - 0.015 15.2 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Abhydrolase_6 PF12697.7 KPI36977.1 - 2e-10 41.6 0.1 7.2e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI36977.1 - 2.9e-08 33.7 0.3 7.6e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KPI36978.1 - 2.3e-30 105.7 27.9 4e-16 58.9 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPI36978.1 - 2.4e-05 23.1 19.6 0.00023 19.9 2.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 KPI36978.1 - 0.00049 19.1 14.6 0.0028 16.6 14.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KPI36978.1 - 0.0011 17.4 5.9 0.021 13.1 2.0 3.1 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KPI36978.1 - 0.0021 17.0 14.6 0.035 13.0 4.8 2.6 1 1 0 2 2 2 2 MFS_1 like family Bac_luciferase PF00296.20 KPI36979.1 - 8.5e-58 196.2 0.3 1.2e-57 195.7 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF5352 PF17303.2 KPI36980.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5352) He_PIG PF05345.12 KPI36981.1 - 1.7e-11 44.1 14.0 0.001 19.2 0.1 5.4 4 1 0 4 4 4 3 Putative Ig domain TMEM154 PF15102.6 KPI36981.1 - 0.0013 18.6 2.4 0.0016 18.4 0.1 2.3 2 0 0 2 2 2 1 TMEM154 protein family BatD PF13584.6 KPI36981.1 - 0.0031 16.4 0.1 0.0056 15.5 0.1 1.3 1 0 0 1 1 1 1 Oxygen tolerance Orf78 PF06024.12 KPI36981.1 - 0.0031 17.8 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 KPI36981.1 - 0.0031 17.4 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Rifin DUF4448 PF14610.6 KPI36981.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Stevor PF17410.2 KPI36981.1 - 0.0076 15.8 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame MGC-24 PF05283.11 KPI36981.1 - 0.041 14.3 0.2 0.041 14.3 0.2 3.3 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 KPI36981.1 - 0.056 14.3 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KPI36981.1 - 0.067 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1180 PF06679.12 KPI36981.1 - 0.068 13.6 0.2 0.068 13.6 0.2 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF1180) DUF2207 PF09972.9 KPI36981.1 - 0.074 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PMP1_2 PF08114.11 KPI36981.1 - 0.14 11.9 3.0 0.3 10.9 3.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Pkinase PF00069.25 KPI36982.1 - 6.1e-56 189.7 0.0 1.9e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI36982.1 - 2.1e-27 96.1 0.0 1.1e-24 87.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 KPI36982.1 - 3.5e-08 33.7 0.0 7.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KPI36982.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPI36982.1 - 0.00039 19.9 0.1 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 KPI36982.1 - 0.0021 18.3 0.0 0.0056 17.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KPI36982.1 - 0.0035 16.2 0.0 0.0072 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KPI36982.1 - 0.09 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KPI36982.1 - 0.11 12.0 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Methyltransf_31 PF13847.6 KPI36983.1 - 6.5e-12 45.5 0.0 1.5e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI36983.1 - 1.4e-05 25.7 0.0 3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI36983.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPI36983.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI36983.1 - 0.0035 18.1 0.0 0.0085 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI36983.1 - 0.0058 17.3 0.1 0.03 15.0 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KPI36983.1 - 0.025 13.7 0.0 0.09 11.9 0.0 1.7 2 0 0 2 2 2 0 mRNA capping enzyme Cut8 PF08559.10 KPI36984.1 - 0.053 13.1 0.2 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein adh_short PF00106.25 KPI36985.1 - 1.2e-25 90.2 1.0 8.1e-25 87.4 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36985.1 - 3.4e-20 72.6 0.2 1.5e-19 70.5 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI36985.1 - 0.0014 18.6 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI36985.1 - 0.0021 17.5 0.1 0.0044 16.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KPI36986.1 - 9.7e-29 100.0 0.0 1.8e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KPI36986.1 - 3e-19 69.4 0.0 5.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 KPI36986.1 - 4.6e-18 65.3 2.3 1.2e-17 64.0 2.3 1.8 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like PfkB PF00294.24 KPI36987.1 - 5.1e-64 216.5 0.0 6.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KPI36987.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase SUR7 PF06687.12 KPI36988.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF202 PF02656.15 KPI36988.1 - 0.048 14.1 0.9 0.089 13.2 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Herpes_gE PF02480.16 KPI36988.1 - 0.059 12.1 0.0 0.066 12.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.6 KPI36988.1 - 0.065 13.5 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4448 PF14610.6 KPI36988.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SCIMP PF15050.6 KPI36988.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 1 0 1 1 1 0 SCIMP protein Amnionless PF14828.6 KPI36988.1 - 0.2 10.5 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF892 PF05974.12 KPI36990.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Glyco_transf_8 PF01501.20 KPI36991.1 - 9e-13 48.4 2.1 1.7e-12 47.4 2.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KPI36991.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 1 0 1 1 1 0 Mannosyltransferase putative adh_short PF00106.25 KPI36992.1 - 9.8e-31 106.7 0.2 1.5e-19 70.2 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI36992.1 - 9.7e-22 77.7 0.0 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI36992.1 - 0.0013 18.3 0.2 0.013 15.0 0.2 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI36992.1 - 0.0052 16.7 0.1 0.011 15.7 0.1 1.5 1 1 0 1 1 1 1 KR domain TAL_FSA PF00923.19 KPI36993.1 - 1.7e-96 322.9 0.1 2e-96 322.7 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SecD-TM1 PF13721.6 KPI36993.1 - 0.0028 18.1 0.2 0.31 11.5 0.0 2.4 2 0 0 2 2 2 2 SecD export protein N-terminal TM region Amidoligase_2 PF12224.8 KPI36994.1 - 2.3e-06 27.5 0.1 1.1 8.9 0.0 3.3 3 0 0 3 3 3 3 Putative amidoligase enzyme MFS_1 PF07690.16 KPI36995.1 - 2.6e-21 75.9 56.4 4.9e-11 42.1 19.5 3.9 2 2 2 4 4 4 3 Major Facilitator Superfamily ABC_membrane PF00664.23 KPI36996.1 - 2.8e-55 187.9 23.7 5.4e-35 121.4 5.1 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI36996.1 - 8.5e-40 136.4 0.1 1.7e-21 77.2 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI36996.1 - 5.2e-08 32.6 0.8 0.002 17.6 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPI36996.1 - 0.00014 21.8 0.1 0.03 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPI36996.1 - 0.00094 19.7 0.0 0.0025 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KPI36996.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KPI36996.1 - 0.031 13.4 0.1 0.064 12.3 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein nsp8 PF08717.10 KPI36996.1 - 0.044 13.7 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 nsp8 replicase Zeta_toxin PF06414.12 KPI36996.1 - 0.062 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KPI36996.1 - 0.17 12.3 0.1 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RskA PF10099.9 KPI36996.1 - 0.3 11.4 2.8 21 5.4 0.0 3.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA SNF2_N PF00176.23 KPI36997.1 - 2.8e-43 148.0 0.0 5.1e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI36997.1 - 6.7e-13 48.9 0.0 2.1e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI36997.1 - 1.5e-10 41.3 0.0 9.8e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_2 PF07647.17 KPI36997.1 - 0.00035 20.6 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DEAD PF00270.29 KPI36997.1 - 0.0016 18.2 0.0 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KPI36997.1 - 0.028 13.7 0.0 0.077 12.2 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Peptidase_S41_N PF11918.8 KPI36997.1 - 0.43 10.8 4.0 0.21 11.8 0.4 2.3 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Bac_luciferase PF00296.20 KPI36998.1 - 5.1e-47 160.8 0.0 8.1e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase RNA_pol_I_A49 PF06870.12 KPI36999.1 - 2.1e-60 204.6 0.5 2.5e-60 204.4 0.5 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF1485 PF07364.12 KPI37000.1 - 1.3e-104 349.6 0.6 1.8e-104 349.1 0.6 1.2 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 KPI37000.1 - 7.5e-61 205.4 0.4 1.1e-60 204.9 0.4 1.2 1 0 0 1 1 1 1 MlrC C-terminus DUF866 PF05907.13 KPI37001.1 - 8.1e-64 214.2 0.2 9.1e-64 214.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.29 KPI37001.1 - 0.069 13.1 1.5 0.15 12.0 1.5 1.6 1 0 0 1 1 1 0 PHD-finger Rubredoxin_2 PF18073.1 KPI37001.1 - 0.08 12.7 5.6 2.3 8.0 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 KPI37001.1 - 0.12 12.4 3.8 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HalOD2 PF18547.1 KPI37001.1 - 0.23 11.4 3.6 0.56 10.1 3.6 1.6 1 1 0 1 1 1 0 Halobacterial output domain 2 DUF4379 PF14311.6 KPI37001.1 - 1 9.8 6.3 0.48 10.8 2.9 2.1 1 1 1 2 2 2 0 Probable Zinc-ribbon domain CH PF00307.31 KPI37002.1 - 5.4e-47 158.5 0.0 2.8e-22 79.0 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KPI37002.1 - 2.4e-25 88.4 0.5 8.3e-25 86.7 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KPI37002.1 - 9.6e-11 41.4 0.2 3.1e-07 30.1 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 KPI37002.1 - 3.1e-05 23.6 0.1 0.00017 21.3 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KPI37002.1 - 0.00063 19.1 0.1 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KPI37002.1 - 0.003 17.4 0.1 0.0091 15.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair DUF1943 PF09172.11 KPI37002.1 - 0.023 13.9 0.6 0.038 13.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Spectrin PF00435.21 KPI37002.1 - 0.13 12.8 7.1 0.97 9.9 0.2 2.8 2 0 0 2 2 2 0 Spectrin repeat EF-hand_7 PF13499.6 KPI37002.1 - 0.38 11.2 2.3 1.3 9.5 0.5 2.8 2 1 0 2 2 2 0 EF-hand domain pair DUF4508 PF14969.6 KPI37002.1 - 0.58 10.5 3.6 4.8 7.5 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) YrbL-PhoP_reg PF10707.9 KPI37003.1 - 0.051 13.1 0.0 0.087 12.3 0.0 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Abhydrolase_1 PF00561.20 KPI37006.1 - 1.1e-15 58.0 0.0 1.8e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37006.1 - 2.3e-15 57.8 10.1 1.6e-14 55.0 10.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37006.1 - 1.1e-07 31.3 0.0 1.3e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KPI37006.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase SH3_1 PF00018.28 KPI37007.1 - 8.8e-13 47.7 0.2 1.7e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI37007.1 - 4.1e-12 45.8 0.3 1.2e-11 44.2 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain BAR PF03114.18 KPI37007.1 - 1.2e-09 38.2 6.2 3.4e-09 36.7 3.3 2.1 2 0 0 2 2 2 1 BAR domain SH3_2 PF07653.17 KPI37007.1 - 1.3e-07 31.1 0.0 3.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF2031 PF09592.10 KPI37007.1 - 1.1 8.8 3.1 1.7 8.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Phage_GP20 PF06810.11 KPI37007.1 - 5.4 6.8 8.9 0.61 9.9 0.2 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 NUDIX PF00293.28 KPI37008.1 - 3.4e-08 33.6 0.0 6.6e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain SUR7 PF06687.12 KPI37009.1 - 8.9e-27 94.1 0.0 2.7e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KPI37009.1 - 0.36 10.7 14.8 0.059 13.3 9.7 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 MFS_1 PF07690.16 KPI37010.1 - 6.3e-27 94.4 25.1 1.2e-26 93.5 24.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_MOT1 PF16983.5 KPI37010.1 - 0.029 14.8 2.0 0.14 12.6 2.4 1.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Rick_17kDa_Anti PF05433.15 KPI37010.1 - 3.3 7.6 7.4 0.15 12.0 1.1 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain UQ_con PF00179.26 KPI37012.1 - 1.1e-39 135.3 0.1 1.5e-39 134.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPI37012.1 - 0.11 12.8 1.7 0.2 11.9 1.7 2.0 1 1 0 1 1 1 0 RWD domain BUD22 PF09073.10 KPI37012.1 - 9.3 5.5 15.5 10 5.3 15.5 1.1 1 0 0 1 1 1 0 BUD22 AA_permease_2 PF13520.6 KPI37013.1 - 2.7e-46 158.3 41.0 6.5e-44 150.4 27.9 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPI37013.1 - 3e-18 65.7 14.2 3e-18 65.7 14.2 3.0 3 0 0 3 3 3 2 Amino acid permease NADHdeh_related PF10125.9 KPI37013.1 - 0.0014 18.0 2.3 0.0037 16.7 2.3 1.7 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein DUF2721 PF11026.8 KPI37013.1 - 9.4 6.1 12.3 2.7 7.9 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) TRP PF06011.12 KPI37014.1 - 2.6e-118 395.4 17.1 3.4e-118 395.1 17.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPI37014.1 - 1.3e-39 135.7 0.0 3.8e-39 134.2 0.0 1.8 2 0 0 2 2 2 1 ML-like domain NADH_dhqG_C PF09326.11 KPI37014.1 - 0.081 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal Gag_MA PF01140.19 KPI37014.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Matrix protein (MA), p15 Myb_DNA-bind_2 PF08914.11 KPI37014.1 - 0.52 10.5 2.4 0.58 10.4 0.6 2.0 2 0 0 2 2 2 0 Rap1 Myb domain Mito_carr PF00153.27 KPI37017.1 - 6.2e-43 144.7 2.7 1.6e-18 66.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_lectin PF07938.12 KPI37020.1 - 3.2e-13 49.7 0.6 6.6e-13 48.7 0.6 1.5 1 1 0 1 1 1 1 Fungal fucose-specific lectin Imm27 PF15590.6 KPI37020.1 - 0.14 12.0 0.4 3.7 7.4 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 27 Inhibitor_I36 PF03995.13 KPI37020.1 - 0.17 11.8 1.0 0.33 10.9 0.8 1.7 1 1 0 1 1 1 0 Peptidase inhibitor family I36 ABC_membrane PF00664.23 KPI37021.1 - 1.3e-38 133.2 15.2 1.8e-38 132.8 15.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPI37021.1 - 2.6e-36 125.2 0.0 5.3e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KPI37021.1 - 2.2e-06 27.3 0.0 0.0014 18.1 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPI37021.1 - 5.8e-06 26.8 0.0 1.5e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KPI37021.1 - 0.00016 21.6 0.1 0.0047 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPI37021.1 - 0.00021 21.6 0.2 0.0019 18.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPI37021.1 - 0.0003 20.6 0.0 0.00074 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KPI37021.1 - 0.0013 18.7 0.0 0.036 14.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KPI37021.1 - 0.0017 18.3 0.1 0.0077 16.2 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 KPI37021.1 - 0.0042 16.4 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KPI37021.1 - 0.008 16.6 0.0 0.062 13.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KPI37021.1 - 0.0099 16.1 0.0 0.042 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPI37021.1 - 0.016 14.9 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KPI37021.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 KPI37021.1 - 0.02 14.7 0.1 0.06 13.0 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KPI37021.1 - 0.03 13.9 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KPI37021.1 - 0.034 14.1 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_ATPase PF09818.9 KPI37021.1 - 0.036 12.9 0.0 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 KPI37021.1 - 0.046 14.2 0.3 0.13 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KPI37021.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPI37021.1 - 0.056 14.0 0.0 0.31 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPI37021.1 - 0.057 13.6 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KPI37021.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KPI37021.1 - 0.073 12.8 0.3 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 KPI37021.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 KPI37021.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KPI37021.1 - 0.14 11.3 0.1 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain HET PF06985.11 KPI37022.1 - 4.7e-10 40.0 10.8 6.7e-09 36.2 2.8 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 KPI37023.1 - 9e-05 21.8 0.0 0.00029 20.1 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KPI37023.1 - 0.00023 21.4 0.0 0.00073 19.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPI37023.1 - 0.00051 20.5 0.0 0.0013 19.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI37023.1 - 0.00072 20.0 0.1 0.0015 19.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KPI37023.1 - 0.00081 19.3 0.0 0.0024 17.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KPI37023.1 - 0.0014 19.2 0.0 0.0043 17.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 KPI37023.1 - 0.0054 16.0 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 KPI37023.1 - 0.008 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPI37023.1 - 0.0094 16.1 1.2 0.02 15.1 0.0 2.2 3 0 0 3 3 2 1 AAA domain PRK PF00485.18 KPI37023.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KPI37023.1 - 0.015 15.7 0.4 0.037 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KPI37023.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 KPI37023.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KPI37023.1 - 0.027 13.5 0.0 0.069 12.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KPI37023.1 - 0.034 13.9 0.0 0.095 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KPI37023.1 - 0.036 13.3 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 KPI37023.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 KPI37023.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TsaE PF02367.17 KPI37023.1 - 0.051 13.6 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KPI37023.1 - 0.062 12.9 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 KPI37023.1 - 0.084 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_25 PF13481.6 KPI37023.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPI37023.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_3 PF07726.11 KPI37023.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KPI37023.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain IMPDH PF00478.25 KPI37024.1 - 1e-126 422.6 2.9 1.3e-126 422.3 2.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KPI37024.1 - 7e-19 68.0 0.0 1.1e-08 35.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KPI37024.1 - 4.9e-07 29.4 6.5 0.06 12.7 7.9 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KPI37024.1 - 1.8e-06 27.2 0.7 3.1e-06 26.5 0.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KPI37024.1 - 9.7e-05 21.9 0.5 0.00022 20.8 0.5 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 KPI37024.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family ThiG PF05690.14 KPI37024.1 - 0.029 13.7 0.4 0.062 12.6 0.4 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PK PF00224.21 KPI37024.1 - 0.035 13.0 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aldolase PF01081.19 KPI37024.1 - 0.091 12.2 0.5 0.4 10.1 0.1 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase Glyoxalase PF00903.25 KPI37025.1 - 3.4e-07 30.5 1.1 1.8e-06 28.2 0.1 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HpcH_HpaI PF03328.14 KPI37026.1 - 2e-27 95.8 0.0 3.4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KPI37026.1 - 0.0002 20.6 0.1 0.0023 17.1 0.0 2.5 2 1 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain Nfu_N PF08712.11 KPI37026.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal p450 PF00067.22 KPI37028.1 - 1.5e-58 198.7 0.0 1.9e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 KPI37029.1 - 1.1e-37 130.2 0.0 1.4e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1190 PF06693.11 KPI37029.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) FMO-like PF00743.19 KPI37030.1 - 1.2e-34 119.7 0.0 1.4e-25 89.7 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI37030.1 - 4.1e-17 62.4 0.0 8.3e-17 61.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI37030.1 - 2.8e-10 40.4 0.0 1.3e-08 35.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPI37030.1 - 4.7e-10 39.1 0.1 4.5e-08 32.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI37030.1 - 5.2e-10 39.0 0.0 8.2e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI37030.1 - 6.3e-07 29.3 0.1 0.28 10.7 0.0 3.3 2 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37030.1 - 1e-05 25.6 0.0 2.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI37030.1 - 1.5e-05 24.4 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KPI37030.1 - 0.015 15.9 0.0 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI37030.1 - 0.019 13.7 0.0 3.7 6.1 0.0 2.4 2 1 0 2 2 2 0 HI0933-like protein Mqo PF06039.15 KPI37030.1 - 0.23 9.9 0.0 0.54 8.7 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Raptor_N PF14538.6 KPI37031.1 - 1.1e-61 207.0 0.0 3.4e-61 205.5 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KPI37031.1 - 0.00017 22.3 2.4 0.61 11.1 0.1 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Cnd1 PF12717.7 KPI37031.1 - 0.0022 18.1 0.2 0.02 15.0 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KPI37031.1 - 0.023 14.9 0.5 8.3 7.0 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Fungal_trans PF04082.18 KPI37033.1 - 9.6e-16 57.6 0.2 1.4e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37033.1 - 2.5e-06 27.5 4.9 4.8e-06 26.6 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.7 KPI37035.1 - 5e-09 36.2 0.0 1.3e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI37035.1 - 7.9e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI37035.1 - 0.0087 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CRIM PF16978.5 KPI37035.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain FAD_binding_3 PF01494.19 KPI37036.1 - 6.7e-18 65.0 0.6 1.5e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI37036.1 - 2.5e-07 30.2 3.7 1.3e-05 24.6 3.6 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI37036.1 - 1.4e-06 28.4 0.1 3e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI37036.1 - 5.3e-06 26.2 3.4 0.0069 16.0 0.8 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI37036.1 - 8.1e-05 23.1 1.4 0.00038 21.0 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37036.1 - 0.00018 20.9 1.3 0.012 14.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI37036.1 - 0.00027 20.4 0.1 0.46 9.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KPI37036.1 - 0.00041 19.6 1.5 0.00093 18.4 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI37036.1 - 0.0012 17.6 2.8 0.017 13.8 0.3 2.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KPI37036.1 - 0.0059 15.9 1.0 0.0059 15.9 1.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KPI37036.1 - 0.015 14.2 2.1 0.34 9.7 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase MscS_porin PF12795.7 KPI37036.1 - 0.028 13.9 13.1 0.054 13.0 13.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Plasmid_RAQPRD PF09686.10 KPI37036.1 - 0.057 13.6 0.3 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) GIDA PF01134.22 KPI37036.1 - 0.076 12.1 8.6 0.013 14.6 2.8 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 KPI37036.1 - 0.09 12.9 1.6 0.23 11.6 0.0 2.5 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 KPI37036.1 - 0.16 11.2 0.2 0.39 9.9 0.2 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KPI37036.1 - 0.2 11.6 1.0 3 7.8 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding UPF0193 PF05250.11 KPI37036.1 - 3.3 7.5 9.1 3.2 7.5 7.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0193) 3HCDH_N PF02737.18 KPI37036.1 - 3.9 7.3 5.7 0.4 10.5 0.6 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIA PF03153.13 KPI37036.1 - 4.2 7.2 21.4 6.6 6.6 21.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD_binding_4 PF01565.23 KPI37037.1 - 2.3e-21 76.0 0.1 5.3e-21 74.8 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI37037.1 - 0.0031 17.6 0.1 0.0082 16.2 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like HAMP PF00672.25 KPI37038.1 - 1.8e-41 140.3 23.0 1.8e-09 37.9 0.1 8.4 7 2 1 8 8 8 6 HAMP domain HATPase_c PF02518.26 KPI37038.1 - 2.7e-30 105.2 2.1 7.1e-30 103.8 0.2 2.8 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI37038.1 - 7e-28 97.0 2.7 1.6e-26 92.7 0.6 2.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPI37038.1 - 2.3e-17 62.8 6.6 7.1e-17 61.2 0.2 4.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 KPI37038.1 - 2.9e-06 27.5 2.0 5.9 7.1 0.0 6.7 7 1 1 8 8 8 1 Domain of unknown function (DUF4279) Laminin_II PF06009.12 KPI37038.1 - 1.3e-05 25.3 39.1 0.54 10.3 0.9 7.5 6 1 1 7 7 7 4 Laminin Domain II Gp-FAR-1 PF05823.12 KPI37038.1 - 0.012 16.0 3.4 7.5 6.9 0.1 4.7 3 2 4 7 7 7 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Helo_like_N PF17111.5 KPI37038.1 - 0.012 15.0 4.4 2.4 7.5 0.1 3.4 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins IL32 PF15225.6 KPI37038.1 - 0.016 15.6 0.8 47 4.4 0.0 4.7 5 1 1 6 6 4 0 Interleukin 32 GhoS PF11080.8 KPI37038.1 - 0.017 15.1 3.9 4 7.5 0.2 4.1 3 0 0 3 3 3 0 Endoribonuclease GhoS CMD PF02627.20 KPI37038.1 - 0.025 14.6 1.4 45 4.2 0.0 4.1 5 0 0 5 5 3 0 Carboxymuconolactone decarboxylase family Fib_alpha PF08702.10 KPI37038.1 - 0.026 14.7 0.8 0.026 14.7 0.8 7.4 6 2 2 8 8 8 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 KPI37038.1 - 0.14 12.2 31.3 12 5.9 0.1 7.7 6 1 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAD_binding_7 PF13241.6 KPI37038.1 - 0.33 11.4 2.8 1.2e+02 3.2 0.0 4.5 3 1 2 5 5 5 0 Putative NAD(P)-binding TSC22 PF01166.18 KPI37038.1 - 0.36 11.2 3.6 61 4.0 0.0 5.1 5 0 0 5 5 4 0 TSC-22/dip/bun family DUF1759 PF03564.15 KPI37038.1 - 0.41 10.6 6.3 22 5.0 0.2 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1759) Lzipper-MIP1 PF14389.6 KPI37038.1 - 0.57 10.5 5.1 1.6 9.1 0.5 3.7 3 0 0 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 DUF948 PF06103.11 KPI37038.1 - 0.97 9.7 60.9 2 8.7 0.3 11.1 5 2 5 10 10 7 0 Bacterial protein of unknown function (DUF948) Tho2 PF11262.8 KPI37038.1 - 1.2 8.3 6.1 0.22 10.7 1.9 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 KPI37038.1 - 6.5 5.9 10.6 1.9 7.6 1.7 3.3 3 1 1 4 4 4 0 TMPIT-like protein EzrA PF06160.12 KPI37038.1 - 7.4 4.6 19.3 0.25 9.5 5.9 3.6 4 1 0 4 4 4 0 Septation ring formation regulator, EzrA DUF3829 PF12889.7 KPI37038.1 - 10 5.5 27.4 1.2 8.6 0.1 5.7 4 3 3 7 7 7 0 Protein of unknown function (DUF3829) AIM24 PF01987.17 KPI37039.1 - 6.1e-44 150.2 0.0 8.6e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Pmp3 PF01679.17 KPI37040.1 - 7.1e-23 80.5 6.9 8.5e-23 80.3 6.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator F-box PF00646.33 KPI37041.1 - 0.00011 22.0 0.0 0.00063 19.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain TPR_2 PF07719.17 KPI37041.1 - 0.0005 20.0 0.1 2.2 8.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 KPI37041.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like TPR_14 PF13428.6 KPI37041.1 - 0.013 16.3 2.1 11 7.1 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI37041.1 - 0.062 13.6 1.2 4.5 7.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TruB_C_2 PF16198.5 KPI37041.1 - 0.11 12.6 0.4 3.4 7.9 0.0 3.2 2 1 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain LRR_4 PF12799.7 KPI37041.1 - 0.14 12.6 5.6 16 6.1 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Abhydrolase_1 PF00561.20 KPI37042.1 - 1.3e-15 57.8 0.0 6.1e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37042.1 - 1.1e-11 45.8 0.1 1.4e-11 45.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37042.1 - 0.0017 17.7 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KPI37042.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein NUDIX PF00293.28 KPI37043.1 - 0.00054 20.0 0.0 0.0038 17.3 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain FAD_binding_3 PF01494.19 KPI37044.1 - 3.3e-68 230.5 0.0 4.3e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPI37044.1 - 1.4e-06 27.6 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KPI37044.1 - 9.5e-06 25.2 0.0 6.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI37044.1 - 1e-05 24.4 0.0 2.1e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KPI37044.1 - 3.7e-05 23.9 0.0 0.00017 21.7 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI37044.1 - 3.8e-05 23.1 0.0 0.0003 20.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI37044.1 - 7.2e-05 22.5 0.1 0.0013 18.4 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KPI37044.1 - 0.0002 20.6 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KPI37044.1 - 0.00029 20.1 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KPI37044.1 - 0.00044 19.4 0.0 0.053 12.6 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPI37044.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI37044.1 - 0.16 12.0 0.2 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KPI37044.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Fungal_trans PF04082.18 KPI37046.1 - 2.9e-13 49.4 0.0 4.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_Rrp7 PF17799.1 KPI37048.1 - 2.9e-32 111.7 0.0 6.7e-32 110.5 0.0 1.6 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KPI37048.1 - 6.2e-28 97.3 7.4 1e-27 96.6 7.4 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 KPI37048.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) HATPase_c PF02518.26 KPI37050.1 - 6.1e-26 91.1 0.0 6.1e-24 84.7 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPI37050.1 - 1.1e-13 51.0 0.0 2.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KPI37050.1 - 1.2e-12 48.0 0.1 2.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain dCache_1 PF02743.18 KPI37050.1 - 2.5e-05 24.2 0.3 4.9e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Cache domain HAMP PF00672.25 KPI37050.1 - 0.0019 18.5 0.0 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 HAMP domain BRCA2 PF00634.18 KPI37050.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 BRCA2 repeat ADH_N PF08240.12 KPI37051.1 - 2.8e-25 88.3 0.9 4.3e-25 87.7 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI37051.1 - 1.4e-21 76.8 0.8 2.2e-21 76.2 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI37051.1 - 1.5e-11 45.5 0.0 3.5e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI37051.1 - 0.0052 17.1 0.2 0.0096 16.2 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KPI37051.1 - 0.089 12.1 0.6 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LtrA PF06772.11 KPI37052.1 - 1.8e-20 73.5 20.0 1.8e-20 73.5 20.0 2.9 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Glyco_hydro_88 PF07470.13 KPI37053.1 - 8.9e-24 84.2 0.0 1.6e-23 83.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Rtt106 PF08512.12 KPI37054.1 - 3e-30 104.5 0.0 6e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KPI37054.1 - 0.00025 21.0 0.5 0.00055 19.9 0.2 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3176 PF11374.8 KPI37055.1 - 2.2e-30 105.0 1.2 6e-30 103.6 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) SNF2_N PF00176.23 KPI37056.1 - 1.5e-31 109.4 0.0 2.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI37056.1 - 2.5e-16 60.0 0.0 4.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KPI37056.1 - 7.6e-06 25.3 0.0 4.4e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MFS_1 PF07690.16 KPI37057.1 - 6.6e-28 97.6 48.5 3.1e-20 72.4 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.28 KPI37058.1 - 8.7e-07 29.0 0.1 1.6e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N PF00107.26 KPI37059.1 - 5e-11 42.7 0.1 9.2e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI37059.1 - 0.00047 20.0 0.0 0.0042 17.0 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI37059.1 - 0.0017 19.4 0.0 0.0027 18.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Inositol_P PF00459.25 KPI37060.1 - 5.1e-61 206.6 0.1 6.2e-61 206.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short PF00106.25 KPI37061.1 - 6.6e-41 139.9 0.7 8.3e-41 139.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37061.1 - 7.5e-31 107.5 0.3 9.5e-31 107.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37061.1 - 4.6e-08 33.2 0.1 7.4e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KPI37061.1 - 2e-06 27.5 0.3 6.2e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KPI37061.1 - 6.6e-06 26.1 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KPI37061.1 - 0.00012 21.5 0.2 0.00096 18.6 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KPI37061.1 - 0.019 14.4 0.1 0.03 13.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPI37061.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FerA PF08165.11 KPI37062.1 - 0.14 12.1 1.4 6.8 6.7 0.0 2.9 3 0 0 3 3 3 0 FerA (NUC095) domain DUF4267 PF14087.6 KPI37063.1 - 5.7e-15 55.4 2.7 7.5e-15 55.0 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PBCV_basic_adap PF08789.10 KPI37064.1 - 0.0048 17.0 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 PBCV-specific basic adaptor domain MLTR_LBD PF17765.1 KPI37064.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain A_deaminase PF00962.22 KPI37065.1 - 1.6e-54 185.4 0.0 2e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KPI37065.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Amidohydro_3 PF07969.11 KPI37065.1 - 0.069 12.6 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family UIM PF02809.20 KPI37066.1 - 0.011 15.7 6.6 0.43 10.6 1.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF3437 PF11919.8 KPI37066.1 - 0.12 12.3 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DIOX_N PF14226.6 KPI37067.1 - 1.7e-17 64.3 0.0 3.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI37067.1 - 1.2e-11 44.9 0.0 4.7e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIR PF00399.19 KPI37069.1 - 1e-85 279.8 128.8 3.9e-07 29.4 1.5 13.4 12 1 1 13 13 13 13 Yeast PIR protein repeat Lactamase_B PF00753.27 KPI37070.1 - 2.5e-08 34.1 1.0 6.2e-08 32.9 1.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI37070.1 - 0.0039 16.7 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAS_8 PF13188.7 KPI37071.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain ADH_zinc_N PF00107.26 KPI37072.1 - 1.9e-10 40.8 0.3 1e-09 38.5 0.1 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI37072.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ABC1 PF03109.16 KPI37073.1 - 1.1e-31 109.5 0.0 1.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Vac14_Fig4_bd PF11916.8 KPI37074.1 - 2e-79 265.4 5.8 2e-79 265.4 5.8 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KPI37074.1 - 1.3e-43 147.5 0.0 2.1e-40 137.2 0.1 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KPI37074.1 - 1.1e-06 29.0 3.8 0.00096 19.6 0.1 5.2 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KPI37074.1 - 1.3e-06 28.1 4.6 0.0014 18.7 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KPI37074.1 - 1.7e-05 25.1 4.7 0.14 12.6 0.0 5.5 6 1 1 7 7 7 2 HEAT repeats Cnd1 PF12717.7 KPI37074.1 - 0.00024 21.2 5.2 0.19 11.7 0.4 4.3 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KPI37074.1 - 0.0022 18.0 0.0 0.66 10.1 0.0 3.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF4551 PF15087.6 KPI37074.1 - 0.073 11.9 2.5 7.3 5.3 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4551) p450 PF00067.22 KPI37075.1 - 3.3e-35 121.7 0.0 4.2e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2842 PF11003.8 KPI37075.1 - 9.1 6.6 8.2 44 4.4 8.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2842) Pkinase PF00069.25 KPI37076.1 - 4.7e-08 32.7 0.0 9.6e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PHD PF00628.29 KPI37076.1 - 9.4e-07 28.6 11.6 1.9e-06 27.7 11.6 1.5 1 0 0 1 1 1 1 PHD-finger Kdo PF06293.14 KPI37076.1 - 8.4e-06 25.3 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI37076.1 - 4.1e-05 23.6 0.1 0.0075 16.2 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KPI37076.1 - 4.2e-05 23.2 0.0 9.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF719 PF05334.13 KPI37076.1 - 0.09 13.0 2.4 0.3 11.3 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF4880 PF16220.5 KPI37076.1 - 0.098 12.6 1.3 2.1 8.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) WaaY PF06176.11 KPI37076.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PHD_2 PF13831.6 KPI37076.1 - 0.36 10.4 5.5 0.7 9.5 5.5 1.5 1 0 0 1 1 1 0 PHD-finger Cactin_mid PF10312.9 KPI37077.1 - 1.7e-59 200.9 0.5 1.7e-59 200.9 0.5 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KPI37077.1 - 3.2e-45 153.1 0.0 3e-44 150.0 0.0 2.1 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein RasGAP PF00616.19 KPI37079.1 - 2.6e-46 158.0 0.0 1.1e-45 155.9 0.0 2.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KPI37079.1 - 7.2e-46 155.7 4.7 7.2e-46 155.7 4.7 2.9 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 KPI37079.1 - 2.5e-12 45.4 50.0 0.39 10.6 0.1 15.9 16 0 0 16 16 16 7 IQ calmodulin-binding motif CH PF00307.31 KPI37079.1 - 2.7e-12 46.8 0.2 1.5e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KPI37079.1 - 0.002 17.9 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain FAA_hydrolase PF01557.18 KPI37080.1 - 2.5e-61 207.2 0.0 3.1e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Zn_clus PF00172.18 KPI37081.1 - 4.4e-07 29.9 10.1 7.2e-07 29.2 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPI37082.1 - 1.6e-31 109.6 25.1 1.6e-31 109.6 25.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI37082.1 - 1.1e-07 31.5 1.8 1.1e-07 31.5 1.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Trp_oprn_chp PF09534.10 KPI37082.1 - 0.0012 18.7 0.3 0.58 9.9 0.3 2.4 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 KPI37082.1 - 0.65 9.9 2.5 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3810 PF12725.7 KPI37082.1 - 0.93 8.8 3.2 2.1 7.6 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) zf-RING_2 PF13639.6 KPI37083.1 - 7.2e-08 32.6 1.1 7.2e-08 32.6 1.1 3.3 3 1 0 3 3 2 1 Ring finger domain PHD PF00628.29 KPI37083.1 - 8.9e-07 28.7 10.3 8.9e-07 28.7 10.3 2.7 2 1 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.6 KPI37083.1 - 3.5e-06 26.8 0.8 3.5e-06 26.8 0.8 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPI37083.1 - 4.3e-06 26.9 0.4 4.3e-06 26.9 0.4 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KPI37083.1 - 1e-05 25.3 0.3 1e-05 25.3 0.3 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI37083.1 - 2.9e-05 23.8 2.4 2.9e-05 23.8 2.4 2.6 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPI37083.1 - 0.00012 22.0 0.4 0.00012 22.0 0.4 2.9 3 1 0 3 3 2 1 zinc-RING finger domain PHD_2 PF13831.6 KPI37083.1 - 0.00015 21.2 3.8 0.00015 21.2 3.8 2.6 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.6 KPI37083.1 - 0.00019 21.2 1.6 0.00019 21.2 1.6 3.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI37083.1 - 0.0002 21.3 0.2 0.0002 21.3 0.2 2.5 2 0 0 2 2 1 1 RING-type zinc-finger DZR PF12773.7 KPI37083.1 - 0.0069 16.4 3.4 0.032 14.3 0.2 2.7 2 1 0 2 2 2 1 Double zinc ribbon Zn_ribbon_17 PF17120.5 KPI37083.1 - 0.024 14.2 0.6 0.024 14.2 0.6 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KPI37083.1 - 0.035 14.2 0.1 0.035 14.2 0.1 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDH-cyt PF16010.5 KPI37085.1 - 4.1e-23 82.0 0.1 6.9e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KPI37085.1 - 1.1e-07 32.0 10.7 1.2e-07 31.9 7.5 2.5 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KPI37085.1 - 0.0012 19.0 5.6 0.012 15.7 1.8 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) DOMON PF03351.17 KPI37085.1 - 0.027 14.7 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 DOMON domain Ferric_reduct PF01794.19 KPI37085.1 - 0.14 12.2 10.7 0.083 13.0 4.5 2.8 2 1 0 2 2 2 0 Ferric reductase like transmembrane component EphA2_TM PF14575.6 KPI37085.1 - 0.91 10.5 0.0 0.91 10.5 0.0 2.7 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2427 PF10348.9 KPI37085.1 - 1.4 8.7 15.4 0.022 14.5 7.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) CPP1-like PF11833.8 KPI37085.1 - 1.6 8.3 4.3 19 4.8 3.0 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2448 PF10476.9 KPI37085.1 - 1.6 8.5 3.8 1.4 8.8 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function C-terminus (DUF2448) HemY_N PF07219.13 KPI37085.1 - 2.2 8.5 6.5 15 5.8 0.5 3.2 3 0 0 3 3 3 0 HemY protein N-terminus DUF2976 PF11190.8 KPI37085.1 - 2.6 7.9 6.4 54 3.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4834 PF16118.5 KPI37085.1 - 4.2 8.4 5.5 5.2 8.1 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Myelin_PLP PF01275.19 KPI37085.1 - 4.9 6.9 6.3 22 4.8 0.1 2.9 3 0 0 3 3 3 0 Myelin proteolipid protein (PLP or lipophilin) DUF2070 PF09843.9 KPI37085.1 - 5.9 5.1 7.3 9.9 4.3 7.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L37ae PF01780.19 KPI37086.1 - 1.4e-40 137.2 10.9 1.6e-40 137.1 10.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KPI37086.1 - 0.0009 19.3 2.8 0.0013 18.8 2.8 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KPI37086.1 - 0.005 16.8 1.6 0.008 16.1 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 KPI37086.1 - 0.016 15.2 0.8 0.023 14.7 0.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 KPI37086.1 - 0.37 10.6 3.7 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Glyco_hydro_88 PF07470.13 KPI37088.1 - 4.1e-10 39.3 0.1 2.2e-08 33.6 0.0 2.7 2 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_8 PF01270.17 KPI37088.1 - 0.079 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 GMC_oxred_N PF00732.19 KPI37089.1 - 3e-44 151.6 0.2 4.8e-44 150.9 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI37089.1 - 3.9e-25 89.0 0.7 3.9e-25 89.0 0.7 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI37089.1 - 7.2e-06 25.3 0.1 0.03 13.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI37089.1 - 1.6e-05 24.3 0.3 0.013 14.8 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37089.1 - 0.0019 17.5 0.1 0.21 10.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Carboxyl_trans PF01039.22 KPI37089.1 - 0.0051 15.5 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain FAD_binding_3 PF01494.19 KPI37089.1 - 0.02 14.2 0.1 0.051 12.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DUF1257 PF06868.11 KPI37089.1 - 0.082 13.2 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) HET PF06985.11 KPI37090.1 - 3.8e-32 111.7 0.4 9e-32 110.4 0.4 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3474 PF11960.8 KPI37091.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Capsid_NCLDV PF04451.12 KPI37091.1 - 0.15 11.8 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Large eukaryotic DNA virus major capsid protein Ysc84 PF04366.12 KPI37093.1 - 9.5e-34 115.9 1.9 1.3e-33 115.5 1.9 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sel1 PF08238.12 KPI37094.1 - 3.6e-28 97.4 27.1 1.5e-05 25.5 0.0 11.1 12 0 0 12 12 12 7 Sel1 repeat ANAPC3 PF12895.7 KPI37094.1 - 0.23 11.7 3.4 17 5.8 0.2 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KPI37094.1 - 0.29 11.2 11.9 7.6 6.8 0.0 6.5 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI37094.1 - 0.75 10.1 15.4 10 6.5 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF1180 PF06679.12 KPI37094.1 - 3.7 7.9 9.0 0.14 12.5 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EHN PF06441.12 KPI37095.1 - 2.7e-16 59.9 0.2 6.2e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI37095.1 - 1.2e-13 51.4 0.2 8.1e-13 48.6 0.1 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37095.1 - 2.8e-05 24.9 1.3 4.5e-05 24.2 1.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.14 KPI37097.1 - 5e-64 216.0 1.0 6.7e-64 215.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_1 PF00583.25 KPI37100.1 - 2.8e-16 59.8 0.0 1.3e-15 57.6 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI37100.1 - 2.3e-08 34.3 0.0 2e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI37100.1 - 6.4e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPI37100.1 - 8.5e-05 23.3 0.1 0.0015 19.2 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI37100.1 - 0.0016 18.4 0.0 0.0057 16.6 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPI37100.1 - 0.0034 17.5 0.1 0.012 15.7 0.0 2.0 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KPI37100.1 - 0.0079 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain dCMP_cyt_deam_1 PF00383.23 KPI37102.1 - 3.5e-10 39.6 0.0 4.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPI37102.1 - 1.9e-08 34.1 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KPI37102.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KPI37102.1 - 0.2 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Senescence PF06911.12 KPI37103.1 - 4.1e-56 190.2 8.7 6.5e-56 189.5 8.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein Sacchrp_dh_NADP PF03435.18 KPI37104.1 - 1e-15 58.2 0.0 1.5e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KPI37104.1 - 0.0027 18.1 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1349 PF07081.11 KPI37105.1 - 2.3e-14 53.5 0.0 3.1e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Gag_p6 PF08705.11 KPI37106.1 - 0.0075 16.5 0.7 0.0075 16.5 0.7 2.1 2 1 0 2 2 2 1 Gag protein p6 RseA_C PF03873.13 KPI37109.1 - 0.76 10.1 2.7 1.5 9.1 2.7 1.4 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Ssu72 PF04722.13 KPI37110.1 - 3.2e-78 261.7 0.0 3.7e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Ilar_coat PF01787.16 KPI37110.1 - 3.3 7.5 6.2 4.3 7.1 5.6 1.5 1 1 0 1 1 1 0 Ilarvirus coat protein Cu-oxidase_3 PF07732.15 KPI37111.1 - 6.4e-42 142.3 4.7 1e-40 138.4 0.4 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPI37111.1 - 2.8e-30 104.9 13.8 7.5e-24 84.0 7.0 4.7 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KPI37111.1 - 1.2e-28 100.2 0.9 3e-28 98.9 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Prefoldin PF02996.17 KPI37113.1 - 2.9e-25 88.5 4.1 7.2e-23 80.8 2.3 3.0 2 1 0 2 2 2 1 Prefoldin subunit TMPIT PF07851.13 KPI37113.1 - 0.0025 17.1 0.9 0.0025 17.1 0.9 1.4 2 0 0 2 2 2 1 TMPIT-like protein Prefoldin_2 PF01920.20 KPI37113.1 - 0.0068 16.3 8.4 0.02 14.8 0.2 3.4 1 1 3 4 4 4 1 Prefoldin subunit YscO PF07321.12 KPI37113.1 - 0.007 16.3 4.1 0.007 16.3 4.1 2.0 1 1 1 2 2 2 1 Type III secretion protein YscO KASH_CCD PF14662.6 KPI37113.1 - 0.012 15.4 5.7 0.23 11.3 1.9 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 KPI37113.1 - 0.018 14.8 4.1 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 KPI37113.1 - 0.036 14.1 1.7 0.094 12.7 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II DHR10 PF18595.1 KPI37113.1 - 0.38 10.8 10.3 0.39 10.8 0.4 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Fzo_mitofusin PF04799.13 KPI37113.1 - 0.78 9.3 3.5 0.5 9.9 0.9 1.9 2 1 0 2 2 2 0 fzo-like conserved region Methyltransf_28 PF02636.17 KPI37114.1 - 1.3e-71 241.3 0.0 1.8e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase adh_short PF00106.25 KPI37114.1 - 4.5e-40 137.2 0.0 6.7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37114.1 - 5.7e-29 101.3 0.1 1.1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37114.1 - 2.2e-08 34.2 0.2 4.2e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37114.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI37114.1 - 0.002 18.1 0.2 0.0037 17.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI37114.1 - 0.0026 17.4 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 KPI37114.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_125 PF06824.11 KPI37115.1 - 3.5e-168 559.8 0.1 4.1e-168 559.6 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Ceramidase_alk PF04734.13 KPI37116.1 - 6.7e-215 714.5 0.0 7.8e-215 714.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KPI37116.1 - 1.3e-58 197.6 0.0 1.9e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Pkinase PF00069.25 KPI37117.1 - 3.8e-57 193.7 0.0 1.1e-56 192.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37117.1 - 8.4e-30 103.9 0.0 1.5e-23 83.5 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KPI37117.1 - 7.6e-07 28.7 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KPI37117.1 - 0.00016 21.7 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPI37117.1 - 0.038 12.9 0.1 0.038 12.9 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KPI37117.1 - 0.041 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KPI37117.1 - 0.044 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.7 KPI37118.1 - 5.7e-09 36.9 0.3 5.7e-08 33.6 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI37118.1 - 1e-05 25.3 0.0 0.0075 15.9 0.1 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI37118.1 - 0.0017 17.7 0.1 0.59 9.3 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 adh_short PF00106.25 KPI37119.1 - 1.5e-42 145.3 0.0 2.1e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37119.1 - 5.4e-31 107.9 0.0 7.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPI37119.1 - 0.00022 21.2 0.1 0.00049 20.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPI37119.1 - 0.00037 20.4 0.1 0.00064 19.7 0.1 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KPI37119.1 - 0.0038 16.8 0.1 0.0067 16.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KPI37119.1 - 0.03 13.8 0.1 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KPI37119.1 - 0.046 13.7 0.2 0.32 11.0 0.0 2.1 1 1 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KPI37119.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_11 PF00457.17 KPI37120.1 - 1.8e-60 203.6 16.9 2.1e-60 203.4 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 FYVE PF01363.21 KPI37122.1 - 9.8e-16 57.7 8.9 1.5e-15 57.1 8.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KPI37122.1 - 2.4 8.4 16.6 0.14 12.4 10.2 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger zf-RING_5 PF14634.6 KPI37122.1 - 3 7.9 10.9 17 5.5 11.0 2.0 1 1 1 2 2 2 0 zinc-RING finger domain DUF1518 PF07469.12 KPI37122.1 - 5 7.6 16.2 0.84 10.1 11.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) MFS_1 PF07690.16 KPI37123.1 - 1.4e-27 96.6 30.8 1.4e-27 96.6 30.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3425 PF11905.8 KPI37129.1 - 1.4e-11 44.4 0.0 3.2e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) ABC_membrane PF00664.23 KPI37130.1 - 1.7e-34 119.8 8.6 2.9e-34 119.0 8.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPI37130.1 - 3.4e-30 105.3 0.0 9.2e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KPI37130.1 - 1.2e-05 24.9 0.5 0.00035 20.1 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPI37130.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KPI37130.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KPI37130.1 - 0.22 11.9 7.2 1.6 9.1 4.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain TFR_dimer PF04253.15 KPI37131.1 - 1.3e-31 109.3 0.3 3.5e-31 107.8 0.2 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KPI37131.1 - 8.7e-17 61.5 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPI37131.1 - 1.4e-08 34.6 0.0 3.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 PA domain FMO-like PF00743.19 KPI37132.1 - 2e-70 237.7 0.0 2.3e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI37132.1 - 2.3e-25 89.5 0.0 2.9e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI37132.1 - 2.9e-17 62.8 0.0 7.9e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI37132.1 - 1e-08 35.2 0.5 0.04 13.5 0.4 3.2 2 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37132.1 - 5.2e-08 33.0 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI37132.1 - 1.4e-07 31.0 0.0 3.4e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KPI37132.1 - 1.5e-07 31.9 0.1 0.0083 16.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI37132.1 - 2e-07 31.1 1.1 7.3e-05 22.8 0.0 4.1 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KPI37132.1 - 0.00026 21.4 0.1 0.37 11.3 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KPI37132.1 - 0.00061 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KPI37132.1 - 0.0017 17.6 0.3 0.0068 15.7 0.1 2.0 3 0 0 3 3 3 1 Thi4 family IlvN PF07991.12 KPI37132.1 - 0.0047 16.5 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KPI37132.1 - 0.011 15.0 0.3 0.022 14.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KPI37132.1 - 0.012 15.7 1.5 2.4 8.2 0.1 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KPI37132.1 - 0.015 14.7 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPI37132.1 - 0.016 13.9 0.1 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KPI37132.1 - 0.056 12.8 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_16 PF10294.9 KPI37132.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Rad54_N PF08658.10 KPI37133.1 - 3.9e-43 147.7 0.2 5.1e-43 147.3 0.2 1.1 1 0 0 1 1 1 1 Rad54 N terminal ADIP PF11559.8 KPI37134.1 - 1.6e-35 122.4 15.6 3.9e-35 121.2 15.6 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KPI37134.1 - 0.0045 16.5 12.4 0.0045 16.5 12.4 1.6 2 0 0 2 2 2 1 Golgin subfamily A member 5 TMPIT PF07851.13 KPI37134.1 - 0.21 10.8 6.0 0.42 9.8 6.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein ROS_MUCR PF05443.11 KPI37134.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.0 3 1 0 3 3 3 0 ROS/MUCR transcriptional regulator protein Ribosomal_L6e PF01159.19 KPI37134.1 - 3.6 8.2 7.8 4.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein L6e RasGAP_C PF03836.15 KPI37135.1 - 0.011 15.9 13.2 0.56 10.3 3.0 3.2 3 0 0 3 3 3 0 RasGAP C-terminus DUF4596 PF15363.6 KPI37135.1 - 0.055 13.7 2.6 0.062 13.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Bac_GDH PF05088.12 KPI37135.1 - 0.82 7.1 5.2 1.2 6.6 5.2 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase SH3_1 PF00018.28 KPI37136.1 - 4.3e-11 42.2 0.0 7.1e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI37136.1 - 3.6e-09 36.3 0.0 6.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI37136.1 - 9.9e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain 2-Hacid_dh_C PF02826.19 KPI37137.1 - 3.3e-50 169.9 0.0 5.4e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI37137.1 - 2.4e-16 59.6 0.0 3.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Fungal_trans PF04082.18 KPI37137.1 - 4e-09 35.9 0.2 1.1e-08 34.5 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain NAD_binding_2 PF03446.15 KPI37137.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase EspB_PE PF18625.1 KPI37137.1 - 0.078 13.5 0.2 0.27 11.7 0.2 1.9 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain PspA_IM30 PF04012.12 KPI37137.1 - 0.13 11.8 2.3 0.11 12.0 0.6 1.7 2 0 0 2 2 2 0 PspA/IM30 family UQ_con PF00179.26 KPI37138.1 - 3.5e-47 159.6 0.0 4.3e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPI37138.1 - 0.00028 21.2 0.1 0.00042 20.6 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KPI37138.1 - 0.0048 16.8 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KPI37138.1 - 0.034 13.8 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B CAF1 PF04857.20 KPI37139.1 - 6.3e-73 245.7 0.0 7.6e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KPI37139.1 - 0.00066 19.4 0.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 2 3'-5' exonuclease Psu PF07455.11 KPI37139.1 - 0.016 14.8 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) FAM212 PF15342.6 KPI37139.1 - 0.2 11.4 0.0 0.52 10.1 0.0 1.6 1 0 0 1 1 1 0 FAM212 family Pkinase PF00069.25 KPI37140.1 - 8.6e-60 202.3 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37140.1 - 5.4e-26 91.4 0.0 7.4e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI37140.1 - 7.6e-09 35.3 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPI37140.1 - 0.00034 20.0 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI37140.1 - 0.017 15.1 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KPI37141.1 - 1.1e-53 182.2 2.3 1.3e-53 182.0 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI37141.1 - 2e-51 174.2 1.7 2e-51 174.2 1.7 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI37141.1 - 1.3e-10 41.5 1.0 1.8e-10 41.0 1.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37141.1 - 5.2e-05 22.8 0.3 0.00023 20.7 0.1 1.9 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPI37141.1 - 0.0039 16.3 0.2 0.0099 15.0 0.1 1.7 1 1 1 2 2 2 1 RmlD substrate binding domain FtsJ PF01728.19 KPI37141.1 - 0.017 15.2 0.1 0.039 14.1 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase GDP_Man_Dehyd PF16363.5 KPI37141.1 - 0.04 13.3 0.1 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Urocanase_C PF17392.2 KPI37141.1 - 0.082 12.3 1.7 0.56 9.6 0.1 2.4 1 1 0 2 2 2 0 Urocanase C-terminal domain NmrA PF05368.13 KPI37141.1 - 0.12 12.0 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Sugar_tr PF00083.24 KPI37142.1 - 8.8e-08 31.4 0.0 9.6e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37142.1 - 8.3e-05 21.7 0.0 9.3e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 KPI37143.1 - 5.1e-12 45.7 0.0 4.6e-11 42.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI37143.1 - 6.9e-12 44.6 0.2 1.1e-10 40.6 0.1 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI37143.1 - 1.2e-10 41.1 0.0 1.6e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI37143.1 - 1.9e-10 40.4 0.0 2.3e-07 30.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI37143.1 - 3.5e-10 39.9 0.1 1.4e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI37143.1 - 5.2e-06 26.3 0.6 9.4e-05 22.2 0.1 2.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI37143.1 - 9.8e-06 24.9 0.0 0.053 12.6 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KPI37143.1 - 1e-05 24.9 0.0 0.00071 18.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KPI37143.1 - 9.1e-05 22.9 0.1 0.036 14.6 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KPI37143.1 - 0.007 15.0 0.0 0.082 11.4 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.6 KPI37143.1 - 0.021 15.2 0.2 0.048 14.1 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.16 KPI37143.1 - 0.022 14.4 0.2 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPI37143.1 - 0.03 14.4 0.0 0.58 10.2 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KPI37143.1 - 0.04 13.0 0.3 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KPI37143.1 - 0.11 12.4 1.3 1.8 8.5 0.1 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding Malic_M PF03949.15 KPI37143.1 - 0.17 11.2 0.0 7.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain p450 PF00067.22 KPI37144.1 - 8.9e-52 176.4 0.0 8.2e-51 173.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 PIR PF00399.19 KPI37145.1 - 5e-06 25.9 3.1 5e-06 25.9 3.1 2.3 2 0 0 2 2 2 1 Yeast PIR protein repeat GDPD PF03009.17 KPI37145.1 - 2.8e-05 24.0 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Kelch_3 PF13415.6 KPI37146.1 - 2e-30 104.5 10.1 7.4e-07 29.3 0.2 6.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KPI37146.1 - 2.7e-29 100.9 11.5 1.1e-05 25.3 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KPI37146.1 - 4.7e-28 96.5 1.3 3.4e-09 36.1 0.2 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KPI37146.1 - 5e-28 96.6 5.2 5e-06 26.4 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KPI37146.1 - 1.4e-26 91.9 4.2 1.5e-07 31.4 0.3 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KPI37146.1 - 7e-20 70.2 8.4 4.5e-07 29.6 0.2 6.7 6 0 0 6 6 6 4 Kelch motif Nrap_D6 PF17407.2 KPI37147.1 - 0.061 13.5 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Nrap protein domain 6 MFS_1 PF07690.16 KPI37148.1 - 1.2e-34 119.8 30.1 1.2e-34 119.8 30.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KPI37149.1 - 1.1e-07 32.4 12.6 0.00074 20.3 1.5 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KPI37149.1 - 3.9e-05 23.2 11.7 3.9e-05 23.2 11.7 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KPI37149.1 - 0.0055 16.9 15.1 0.017 15.3 15.1 1.7 1 1 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 KPI37149.1 - 0.024 15.0 0.2 4.8 7.5 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DZR PF12773.7 KPI37149.1 - 0.033 14.2 12.9 0.27 11.3 12.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KPI37149.1 - 0.13 11.7 5.3 0.2 11.1 2.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain eIF2A PF08662.11 KPI37149.1 - 0.15 11.9 0.0 1 9.2 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A C1_1 PF00130.22 KPI37149.1 - 0.48 10.4 8.1 4.4 7.3 8.1 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 KPI37149.1 - 0.52 10.1 6.4 0.24 11.2 2.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-rbx1 PF12678.7 KPI37149.1 - 2.2 8.7 14.0 8.8 6.7 14.0 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_9 PF13901.6 KPI37149.1 - 3.8 7.5 8.7 7.9 6.4 8.7 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_2 PF13639.6 KPI37149.1 - 8.8 6.8 21.2 0.044 14.1 7.1 2.8 2 1 0 2 2 2 0 Ring finger domain Transp_cyt_pur PF02133.15 KPI37150.1 - 6.5e-20 71.3 27.1 1.4e-19 70.2 27.1 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin tRNA-synt_2 PF00152.20 KPI37151.1 - 5.4e-59 199.8 0.0 8e-44 150.0 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) HDA2-3 PF11496.8 KPI37151.1 - 7.3e-11 41.8 0.8 9.9e-10 38.1 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 tRNA_anti-codon PF01336.25 KPI37151.1 - 4.3e-07 29.8 0.0 8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KPI37151.1 - 0.14 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Spc7 PF08317.11 KPI37151.1 - 3.4 6.5 33.3 0.54 9.1 14.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.18 KPI37151.1 - 3.8 7.8 9.0 1.2 9.4 0.1 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper FAD_binding_3 PF01494.19 KPI37152.1 - 1.1e-16 61.0 0.1 1.2e-15 57.6 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI37152.1 - 1.8e-08 34.3 3.1 4.4e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37152.1 - 4.8e-06 26.7 0.9 1.7e-05 24.9 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI37152.1 - 2e-05 23.9 0.3 4.9e-05 22.6 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KPI37152.1 - 0.00035 21.1 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI37152.1 - 0.00079 18.2 0.3 0.0039 16.0 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPI37152.1 - 0.00082 18.7 0.6 0.025 13.8 0.2 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37152.1 - 0.016 14.4 0.5 0.03 13.6 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI37152.1 - 0.051 12.9 0.9 0.086 12.2 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KPI37152.1 - 0.081 12.0 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.19 KPI37152.1 - 0.15 10.4 0.1 0.27 9.6 0.1 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HET PF06985.11 KPI37153.1 - 1.3e-23 84.0 0.1 1.5e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KPI37157.1 - 9.1e-38 130.1 25.2 9.1e-38 130.1 25.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI37157.1 - 3.1e-14 52.7 20.9 7.9e-14 51.4 7.7 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KPI37157.1 - 6.2e-10 38.1 5.2 6.2e-10 38.1 5.2 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KPI37157.1 - 0.00019 20.4 11.4 0.0038 16.1 1.2 2.7 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 KPI37157.1 - 0.01 14.1 9.0 0.0039 15.5 4.2 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SsgA PF04686.12 KPI37157.1 - 0.011 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA CENP-L PF13092.6 KPI37157.1 - 0.038 14.2 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Aldo_ket_red PF00248.21 KPI37158.1 - 3.1e-40 138.2 0.0 5.4e-40 137.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family SRP_TPR_like PF17004.5 KPI37159.1 - 2.1e-18 66.4 1.7 5.8e-18 65.0 1.7 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 KPI37159.1 - 1.9e-17 63.4 2.8 7.3e-17 61.5 2.8 2.0 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KPI37159.1 - 0.0031 18.0 29.3 1.9 9.0 0.1 6.8 4 2 2 6 6 6 4 Tetratricopeptide repeat FAM163 PF15069.6 KPI37159.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 FAM163 family ANAPC3 PF12895.7 KPI37159.1 - 0.06 13.6 10.7 1.1 9.5 4.2 4.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KPI37159.1 - 0.36 11.0 18.4 2.4 8.5 1.9 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI37159.1 - 0.97 10.2 15.4 1.3 9.8 2.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI37159.1 - 1.2 9.9 7.2 2.8e+02 2.6 2.6 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI37159.1 - 4.4 8.4 22.8 6.8 7.8 0.3 6.8 7 1 1 8 8 8 0 Tetratricopeptide repeat SMBP PF16785.5 KPI37160.1 - 0.0066 16.7 1.8 0.0085 16.3 1.8 1.2 1 0 0 1 1 1 1 Small metal-binding protein Sugar_tr PF00083.24 KPI37161.1 - 2e-19 69.8 5.8 2e-19 69.8 5.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37161.1 - 2.4e-10 39.9 25.7 3.3e-10 39.4 25.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 KPI37161.1 - 2.5 6.3 4.6 3.7 5.7 4.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungal_trans_2 PF11951.8 KPI37162.1 - 1.4e-06 27.4 0.7 2.6e-06 26.5 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 KPI37163.1 - 1.4e-113 380.4 0.4 1.8e-113 380.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPI37163.1 - 4.3e-16 59.0 0.2 1.2e-15 57.5 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like ACTH_assoc PF16102.5 KPI37163.1 - 1.2 10.1 2.6 1.2 10.0 0.3 2.2 2 0 0 2 2 2 0 ACTH-associated domain Abhydrolase_4 PF08386.10 KPI37164.1 - 2.5e-21 75.7 0.0 3.4e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KPI37164.1 - 8.7e-13 48.5 0.0 9.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Beta-lactamase PF00144.24 KPI37165.1 - 5.5e-21 75.2 0.1 1.1e-20 74.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 KPI37165.1 - 1.3e-18 67.0 0.0 2.3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhoD PF09423.10 KPI37167.1 - 2.7e-114 381.8 0.5 3.4e-114 381.5 0.5 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KPI37167.1 - 3.6e-33 114.0 0.2 8.5e-33 112.8 0.2 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KPI37167.1 - 1.5e-06 28.6 2.5 2.6e-06 27.9 1.3 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain DUF3455 PF11937.8 KPI37168.1 - 2.2e-33 115.9 0.1 3e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CK_II_beta PF01214.18 KPI37170.1 - 2.1e-75 252.6 0.2 3.1e-75 252.0 0.2 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Oxysterol_BP PF01237.18 KPI37171.1 - 2.5e-117 391.8 2.9 1.3e-116 389.5 2.9 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KPI37171.1 - 4.8e-40 135.7 0.9 4.9e-39 132.5 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KPI37171.1 - 4.2e-08 33.7 0.7 9.1e-07 29.4 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 KPI37171.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 KPI37171.1 - 1 9.8 6.7 15 6.1 0.1 3.5 2 1 1 3 3 3 0 Pleckstrin homology domain RNA_pol_Rpb5_C PF01191.19 KPI37172.1 - 5.4e-34 115.9 0.0 8.8e-34 115.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KPI37172.1 - 3.1e-22 78.9 0.0 5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain SH3_2 PF07653.17 KPI37172.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Ribonuclease PF00545.20 KPI37173.1 - 9.7e-07 29.5 0.1 1.3e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 ribonuclease UCH PF00443.29 KPI37175.1 - 1.1e-24 87.3 0.0 1.9e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI37175.1 - 3.6e-10 39.9 0.1 1.1e-09 38.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 KPI37177.1 - 1.1e-51 172.7 1.7 6.6e-17 61.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrpF PF04303.13 KPI37178.1 - 2.1e-49 168.5 0.0 1.6e-41 142.6 0.0 2.2 2 0 0 2 2 2 2 PrpF protein Ribosomal_L7Ae PF01248.26 KPI37179.1 - 7e-26 89.8 1.2 1.5e-25 88.7 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_2 PF12796.7 KPI37179.1 - 1.2e-22 80.3 0.0 3.7e-08 33.9 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI37179.1 - 1.7e-17 63.5 0.0 2.8e-06 27.7 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI37179.1 - 1.2e-15 56.0 1.5 0.0011 19.3 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KPI37179.1 - 2.4e-15 56.4 1.8 2.6e-05 24.4 0.0 4.8 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KPI37179.1 - 1e-11 44.7 0.6 0.0028 18.0 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat HC2 PF07382.11 KPI37179.1 - 4.1 7.4 26.3 0.4 10.7 21.1 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 CorA PF01544.18 KPI37180.1 - 3e-11 43.2 0.0 5.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Methyltr_RsmB-F PF01189.17 KPI37181.1 - 9.1e-32 110.3 0.0 3e-24 85.8 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KPI37181.1 - 0.0023 18.1 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3292 PF11696.8 KPI37182.1 - 3.8e-227 755.8 0.0 1.2e-156 522.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 KPI37182.1 - 0.017 14.9 0.7 0.076 12.8 0.5 1.9 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 KPI37182.1 - 0.019 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_1 PF07690.16 KPI37183.1 - 2e-31 109.3 32.0 3e-30 105.4 32.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI37183.1 - 0.003 16.5 0.1 0.003 16.5 0.1 3.0 2 1 2 4 4 4 1 MFS_1 like family CHCH PF06747.13 KPI37184.1 - 0.024 14.8 1.4 0.051 13.7 1.4 1.5 1 1 0 1 1 1 0 CHCH domain NDUF_B7 PF05676.13 KPI37184.1 - 0.079 12.7 0.6 0.096 12.4 0.6 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KPI37184.1 - 0.29 11.5 3.2 11 6.4 0.2 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Fer4 PF00037.27 KPI37185.1 - 3.2e-14 52.1 16.2 2.1e-08 33.6 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KPI37185.1 - 9.4e-14 51.7 9.9 1.5e-13 51.1 9.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KPI37185.1 - 8.9e-11 42.6 7.0 2.7e-05 25.0 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KPI37185.1 - 4.7e-10 39.5 5.3 0.00015 21.8 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KPI37185.1 - 6.8e-10 38.9 21.3 3.1e-07 30.4 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KPI37185.1 - 1.3e-08 34.9 9.8 2.1e-08 34.2 9.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KPI37185.1 - 1.5e-07 31.8 19.9 4e-05 24.0 11.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KPI37185.1 - 9.1e-07 28.6 12.2 0.003 17.6 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KPI37185.1 - 2.5e-06 27.3 16.6 0.001 19.0 5.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KPI37185.1 - 1.9e-05 24.8 10.6 0.00081 19.7 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KPI37185.1 - 5.8e-05 23.5 11.9 0.0057 17.2 12.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KPI37185.1 - 0.0027 18.5 16.3 0.018 15.9 3.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 KPI37185.1 - 0.028 15.0 14.9 0.8 10.3 4.1 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KPI37185.1 - 0.033 14.4 5.2 0.78 10.0 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KPI37185.1 - 0.05 13.8 9.6 29 4.9 9.2 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KPI37185.1 - 0.13 13.1 11.2 0.97 10.3 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain hGDE_central PF14702.6 KPI37185.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme ETF_QO PF05187.13 KPI37185.1 - 0.32 11.2 5.6 1.5 9.0 4.3 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 KPI37185.1 - 0.4 10.7 5.7 0.18 11.9 0.6 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins Lar_restr_allev PF14354.6 KPI37185.1 - 4 7.9 7.7 3.4 8.1 0.7 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF3535 PF12054.8 KPI37186.1 - 2.2e-106 356.7 0.1 1.7e-105 353.8 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KPI37186.1 - 2e-68 230.7 0.0 7.5e-67 225.5 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI37186.1 - 9.2e-15 55.0 0.0 2.4e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KPI37186.1 - 1.6e-10 40.3 13.5 0.012 15.8 0.0 9.0 11 0 0 11 11 10 3 HEAT repeat HEAT_2 PF13646.6 KPI37186.1 - 6e-05 23.3 10.1 0.0058 17.0 0.1 5.5 5 0 0 5 5 4 1 HEAT repeats DEAD PF00270.29 KPI37186.1 - 0.00037 20.3 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KPI37186.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TAF6_C PF07571.13 KPI37186.1 - 0.11 12.8 0.1 1.4 9.2 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 KPI37186.1 - 0.19 12.4 0.8 13 6.5 0.0 4.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KPI37186.1 - 1 9.9 16.8 1.1 9.9 0.0 7.1 8 0 0 8 8 7 0 HEAT-like repeat PhdYeFM_antitox PF02604.19 KPI37186.1 - 3.3 7.6 5.1 3.2 7.6 0.2 3.4 3 0 0 3 3 3 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Abhydrolase_1 PF00561.20 KPI37188.1 - 1.4e-16 60.9 0.1 7.4e-10 38.9 0.1 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI37188.1 - 3.4e-13 49.4 0.1 3.6e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI37188.1 - 1.7e-08 35.3 3.2 1.9e-06 28.6 0.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KPI37188.1 - 0.00096 19.0 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPI37188.1 - 0.0015 18.1 0.1 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KPI37188.1 - 0.0027 17.4 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 KPI37188.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KPI37188.1 - 0.042 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KPI37188.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyoxal_oxid_N PF07250.11 KPI37190.1 - 2.8e-20 72.5 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus Abhydrolase_6 PF12697.7 KPI37191.1 - 2.4e-09 38.1 0.0 3.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37191.1 - 6.7e-05 22.3 0.0 0.00025 20.4 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI37191.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M22 PF00814.25 KPI37192.1 - 4.7e-59 200.3 0.0 5.7e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Amidohydro_2 PF04909.14 KPI37194.1 - 2.5e-35 122.7 1.4 3.6e-35 122.1 1.4 1.2 1 1 0 1 1 1 1 Amidohydrolase Cupin_1 PF00190.22 KPI37195.1 - 5.7e-20 71.4 0.4 7.9e-20 71.0 0.4 1.2 1 0 0 1 1 1 1 Cupin MAPEG PF01124.18 KPI37196.1 - 7e-18 64.8 0.4 1e-17 64.3 0.4 1.2 1 0 0 1 1 1 1 MAPEG family SGL PF08450.12 KPI37197.1 - 0.0026 17.4 0.0 0.0067 16.0 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KPI37197.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Arylesterase RasGEF PF00617.19 KPI37199.1 - 7.8e-45 153.2 0.1 1.3e-44 152.5 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPI37199.1 - 4.3e-12 46.2 0.3 1.1e-11 44.9 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.19 KPI37200.1 - 8.4e-29 99.9 1.5 1.7e-28 98.9 1.5 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KPI37200.1 - 4.8e-13 49.5 0.2 3.4e-12 46.8 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPI37200.1 - 4.2e-11 42.8 0.1 0.0017 18.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KPI37200.1 - 1.6e-10 41.0 0.1 6.7e-07 29.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KPI37200.1 - 1.8e-09 38.0 0.0 2.5e-07 31.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI37200.1 - 1.5e-07 31.1 2.3 0.003 17.9 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Amidase PF01425.21 KPI37201.1 - 3.3e-62 210.9 3.7 1.1e-59 202.6 1.9 2.6 2 1 0 3 3 3 2 Amidase LRR_5 PF13306.6 KPI37201.1 - 0.17 11.9 0.0 0.47 10.4 0.1 1.7 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) COesterase PF00135.28 KPI37202.1 - 3e-84 283.7 0.0 4e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI37202.1 - 2.1e-06 27.8 0.0 5.9e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold CT_A_B PF02626.15 KPI37203.1 - 6.4e-77 258.7 0.0 1.3e-76 257.7 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KPI37203.1 - 3.4e-55 186.8 0.0 6.2e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KPI37203.1 - 4e-38 130.4 0.0 1.2e-37 128.8 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KPI37203.1 - 1.2e-29 102.6 0.0 4.2e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 KPI37203.1 - 1.2e-23 83.9 0.0 2.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 KPI37203.1 - 1.1e-10 41.2 3.3 4.6e-10 39.2 3.3 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KPI37203.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KPI37203.1 - 0.037 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 KPI37203.1 - 0.077 12.4 0.2 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Amidase PF01425.21 KPI37204.1 - 1.4e-31 110.0 0.0 2.2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF4817 PF16087.5 KPI37204.1 - 1.5 8.7 5.0 0.89 9.4 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DAO PF01266.24 KPI37206.1 - 6.8e-29 101.5 2.0 8.2e-29 101.3 2.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37206.1 - 0.00024 21.3 1.5 0.00032 20.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI37206.1 - 0.0011 18.3 0.0 0.0011 18.3 0.0 2.2 2 1 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KPI37206.1 - 0.0043 16.3 4.4 0.0067 15.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI37206.1 - 0.0062 15.7 0.9 0.007 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KPI37206.1 - 0.061 13.6 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AAA_12 PF13087.6 KPI37207.1 - 2e-28 99.4 0.0 3.9e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPI37207.1 - 1.3e-12 48.1 1.0 2.3e-07 30.9 0.0 2.7 2 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KPI37207.1 - 4.7e-08 33.0 0.0 1.7e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KPI37207.1 - 0.0001 22.6 0.0 0.0079 16.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI37207.1 - 0.00041 20.8 0.0 0.0071 16.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KPI37207.1 - 0.001 19.3 0.0 0.37 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KPI37207.1 - 0.0068 16.8 0.0 0.047 14.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KPI37207.1 - 0.0071 16.1 0.0 0.027 14.3 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KPI37207.1 - 0.0073 16.1 0.0 0.16 11.7 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KPI37207.1 - 0.014 14.9 0.0 0.071 12.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 KPI37207.1 - 0.023 14.6 0.0 0.069 13.1 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 KPI37207.1 - 0.045 13.7 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KPI37207.1 - 0.088 12.7 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KPI37207.1 - 0.11 12.7 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KPI37207.1 - 0.17 12.4 0.6 1.5 9.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain CorA PF01544.18 KPI37209.1 - 3.6e-08 33.1 0.6 6.1e-08 32.3 0.6 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.6 KPI37209.1 - 0.056 13.7 3.3 0.44 10.8 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CitMHS PF03600.16 KPI37209.1 - 0.078 12.2 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter Ig_mannosidase PF17753.1 KPI37209.1 - 0.11 12.2 0.7 0.38 10.5 0.1 2.2 2 0 0 2 2 2 0 Ig-fold domain SPC12 PF06645.13 KPI37209.1 - 1.6 8.9 5.3 0.56 10.3 2.0 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ABM PF03992.16 KPI37210.1 - 3.1e-05 24.0 0.8 0.0086 16.2 0.7 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SOR PF07682.11 KPI37210.1 - 0.17 10.7 0.0 5.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Sulphur oxygenase reductase HET PF06985.11 KPI37211.1 - 1.6e-18 67.5 0.0 4.3e-18 66.1 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fumble PF03630.14 KPI37213.1 - 3.1e-140 467.0 0.3 4e-140 466.7 0.3 1.1 1 0 0 1 1 1 1 Fumble SLC35F PF06027.12 KPI37214.1 - 2.6e-87 293.1 17.8 3.2e-87 292.8 17.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KPI37214.1 - 2.1e-11 43.4 6.5 2.1e-11 43.4 6.5 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KPI37214.1 - 0.00025 21.2 27.9 0.0011 19.2 13.1 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 KPI37214.1 - 0.011 15.1 7.9 0.19 11.1 4.9 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family MFS_1 PF07690.16 KPI37215.1 - 3e-07 29.7 49.5 3.4e-05 23.0 46.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2b PF00587.25 KPI37216.1 - 6.8e-30 104.4 0.1 1.7e-27 96.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KPI37216.1 - 1e-17 64.0 0.2 2.3e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KPI37216.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KPI37216.1 - 0.00038 20.5 0.0 0.00095 19.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain MotCF PF09158.10 KPI37216.1 - 0.17 11.9 0.1 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal Cytochrom_B561 PF03188.16 KPI37217.1 - 7.4e-19 68.2 1.2 1.4e-18 67.3 1.2 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KPI37217.1 - 5.9e-07 29.7 5.5 0.00079 19.6 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) SdpI PF13630.6 KPI37217.1 - 3 8.0 17.2 0.2 11.8 1.1 3.5 3 1 0 3 3 3 0 SdpI/YhfL protein family TctB PF07331.11 KPI37217.1 - 3.6 7.9 15.4 1.5e+02 2.7 15.4 2.3 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4231 PF14015.6 KPI37217.1 - 3.8 8.0 5.6 16 6.0 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Amido_AtzD_TrzD PF09663.10 KPI37218.1 - 2.1e-113 379.0 2.0 2.5e-113 378.8 2.0 1.0 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) His_Phos_2 PF00328.22 KPI37219.1 - 5.6e-33 114.8 0.0 7.7e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S41 PF03572.18 KPI37221.1 - 2.8e-05 23.7 0.0 7.2e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 EF-hand_1 PF00036.32 KPI37222.1 - 1.6e-27 92.9 12.4 1.7e-08 33.4 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KPI37222.1 - 3.2e-22 78.8 7.2 6.7e-14 52.1 1.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KPI37222.1 - 3.7e-21 73.2 5.1 0.00012 21.7 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KPI37222.1 - 2.6e-19 67.8 10.4 1.3e-07 30.8 0.4 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KPI37222.1 - 1.3e-10 40.9 13.4 0.00032 20.5 0.4 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KPI37222.1 - 1.3e-05 25.5 0.0 0.04 14.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KPI37222.1 - 2.3e-05 24.3 7.8 0.021 14.8 0.3 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand ATP-cone PF03477.16 KPI37222.1 - 0.033 14.7 0.1 0.07 13.7 0.1 1.5 1 0 0 1 1 1 0 ATP cone domain EF-hand_9 PF14658.6 KPI37222.1 - 0.092 13.1 0.3 0.4 11.1 0.1 2.1 3 0 0 3 3 3 0 EF-hand domain AMPK1_CBM PF16561.5 KPI37223.1 - 5.7e-23 81.0 0.1 9.4e-23 80.2 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KPI37223.1 - 6.1e-22 77.7 2.0 7.7e-22 77.3 0.3 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Exo_endo_phos PF03372.23 KPI37226.1 - 6.5e-05 22.6 0.0 0.00017 21.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ETF_QO PF05187.13 KPI37227.1 - 2.1e-44 149.9 1.3 5e-44 148.7 0.9 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KPI37227.1 - 3.4e-07 30.2 0.4 0.00015 21.5 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37227.1 - 3.4e-07 30.4 0.0 9.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI37227.1 - 2.2e-05 23.8 0.0 5.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI37227.1 - 8.2e-05 22.0 0.0 0.00056 19.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KPI37227.1 - 0.00014 21.1 0.5 0.0021 17.2 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KPI37227.1 - 0.00014 21.2 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI37227.1 - 0.00027 19.8 0.2 0.00039 19.2 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KPI37227.1 - 0.00087 19.8 0.1 2.8 8.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI37227.1 - 0.0011 19.0 0.1 0.003 17.6 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI37227.1 - 0.0013 18.1 0.2 0.0021 17.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI37227.1 - 0.0031 16.5 0.1 0.23 10.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KPI37227.1 - 0.022 13.8 0.1 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.7 KPI37227.1 - 0.029 15.0 0.6 0.11 13.1 0.7 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KPI37227.1 - 0.15 12.3 0.7 0.39 10.9 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 KPI37227.1 - 0.16 11.0 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KPI37227.1 - 0.16 11.3 3.2 0.12 11.7 1.2 1.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase UreF PF01730.16 KPI37228.1 - 1.1e-18 68.0 0.1 1.4e-18 67.7 0.1 1.1 1 0 0 1 1 1 1 UreF DUF3433 PF11915.8 KPI37230.1 - 1.1e-31 109.1 9.9 9.1e-18 64.5 1.6 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2569 PF10754.9 KPI37230.1 - 0.026 15.0 0.7 0.026 15.0 0.7 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2569) LptF_LptG PF03739.14 KPI37230.1 - 0.059 12.2 0.1 0.059 12.2 0.1 2.2 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG SUR7 PF06687.12 KPI37230.1 - 0.27 10.8 4.0 6.2 6.4 1.0 3.1 3 0 0 3 3 3 0 SUR7/PalI family DUF1929 PF09118.11 KPI37231.1 - 4.4e-19 68.6 0.0 6.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KPI37231.1 - 0.016 15.5 0.1 1.4 9.3 0.0 3.1 2 1 1 3 3 3 0 Kelch motif Ino80_Iec3 PF14612.6 KPI37232.1 - 6.6e-62 210.3 2.9 9.2e-62 209.8 2.9 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Dynamin_N PF00350.23 KPI37234.1 - 2.6e-33 115.4 0.0 5.8e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KPI37234.1 - 3.2e-19 69.2 0.0 6.6e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KPI37234.1 - 1.9e-05 24.7 0.0 0.00015 21.8 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 KPI37234.1 - 0.011 15.8 0.0 0.035 14.2 0.0 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain FeoB_N PF02421.18 KPI37234.1 - 0.11 12.1 0.0 8.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Wzy_C_2 PF11846.8 KPI37235.1 - 0.064 13.2 1.2 0.076 12.9 1.2 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal bZIP_1 PF00170.21 KPI37237.1 - 2.7e-07 30.6 8.0 3.6e-07 30.2 8.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI37237.1 - 2.4e-05 24.3 8.3 3.5e-05 23.8 8.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper GvpL_GvpF PF06386.11 KPI37237.1 - 0.033 14.1 2.1 0.039 13.9 2.1 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CCDC-167 PF15188.6 KPI37237.1 - 0.037 14.3 4.9 0.056 13.8 4.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 bZIP_Maf PF03131.17 KPI37237.1 - 0.19 12.2 8.4 0.27 11.8 8.4 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.6 KPI37237.1 - 0.44 9.8 3.4 0.56 9.5 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_26 PF13500.6 KPI37238.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Bromo_TP_like PF17027.5 KPI37238.1 - 0.1 12.8 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Histone-fold protein TT1725 PF18324.1 KPI37238.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Hypothetical protein TT1725 PEHE PF15275.6 KPI37239.1 - 0.95 10.1 9.0 0.18 12.4 1.2 2.2 1 1 0 2 2 2 0 PEHE domain WD40 PF00400.32 KPI37241.1 - 6.9e-18 64.7 15.5 0.0062 17.4 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KPI37241.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A 3-dmu-9_3-mt PF06983.13 KPI37243.1 - 1.1e-22 80.8 0.0 2.6e-22 79.6 0.0 1.6 1 1 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DLH PF01738.18 KPI37243.1 - 1.9e-13 50.5 0.0 1.7e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family T6PP_N PF18572.1 KPI37244.1 - 0.058 13.2 0.1 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Peptidase_C13 PF01650.18 KPI37245.1 - 6.2e-43 147.2 0.0 8.3e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Ndufs5 PF10200.9 KPI37246.1 - 0.00017 21.8 0.1 0.00021 21.5 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KPI37246.1 - 0.00042 20.6 0.6 0.016 15.5 0.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3128) COX6B PF02297.17 KPI37246.1 - 0.21 11.8 0.2 0.21 11.8 0.2 1.9 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Tautomerase_3 PF14832.6 KPI37247.1 - 3.7e-49 166.5 0.1 4.1e-49 166.3 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Arrestin_C PF02752.22 KPI37250.1 - 2.7e-09 37.6 0.0 9e-07 29.4 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KPI37250.1 - 5.1e-05 23.4 0.7 0.0015 18.6 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain RXT2_N PF08595.11 KPI37251.1 - 2.5e-35 121.8 0.0 2.5e-35 121.8 0.0 3.5 3 1 1 4 4 4 1 RXT2-like, N-terminal GREB1 PF15782.5 KPI37251.1 - 5.4 4.0 7.0 6.9 3.7 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sulfotransfer_4 PF17784.1 KPI37252.1 - 7.5e-67 225.3 0.0 8.8e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI37252.1 - 0.023 15.1 0.3 0.12 12.7 0.0 2.2 1 1 1 2 2 2 0 Sulfotransferase family DLH PF01738.18 KPI37253.1 - 7.3e-27 94.3 0.0 8.4e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KPI37253.1 - 0.066 13.1 0.1 4 7.3 0.0 2.6 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KPI37253.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_43 PF04616.14 KPI37254.1 - 6.6e-30 104.4 0.0 8.4e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.22 KPI37255.1 - 8.5e-40 136.9 0.0 1.1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TMF_TATA_bd PF12325.8 KPI37257.1 - 0.14 12.4 2.3 0.22 11.7 1.7 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding p450 PF00067.22 KPI37259.1 - 3.3e-59 200.9 0.0 1.4e-58 198.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 CcmH PF03918.14 KPI37259.1 - 0.081 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein UQ_con PF00179.26 KPI37260.1 - 5.1e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3454 PF11936.8 KPI37260.1 - 0.066 13.6 5.5 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) IFRD PF05004.13 KPI37265.1 - 1.3e-71 241.3 16.5 1.9e-71 240.7 16.5 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KPI37265.1 - 0.033 14.6 7.9 1.4 9.3 0.7 3.0 2 1 0 3 3 3 0 HEAT repeats Corona_nucleoca PF00937.18 KPI37265.1 - 2.2 7.2 6.5 2.1 7.3 4.9 1.8 2 1 0 2 2 2 0 Coronavirus nucleocapsid protein Methyltransf_24 PF13578.6 KPI37266.1 - 6e-10 40.1 0.2 1.3e-09 39.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 KPI37266.1 - 0.00038 19.7 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase DUF1442 PF07279.11 KPI37266.1 - 0.038 13.3 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1442) Podoplanin PF05808.11 KPI37267.1 - 0.00093 19.3 2.8 0.00093 19.3 2.8 1.9 3 0 0 3 3 3 1 Podoplanin DUF1206 PF06724.11 KPI37267.1 - 0.0028 17.7 0.7 0.011 15.8 0.7 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) VSP PF03302.13 KPI37267.1 - 0.0028 16.6 1.3 0.005 15.7 1.3 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Amnionless PF14828.6 KPI37267.1 - 0.0063 15.4 0.0 0.0084 15.0 0.0 1.1 1 0 0 1 1 1 1 Amnionless LapA_dom PF06305.11 KPI37267.1 - 0.014 15.1 1.1 0.03 14.1 0.3 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF347 PF03988.12 KPI37267.1 - 0.021 15.0 0.3 0.046 13.9 0.3 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF4381 PF14316.6 KPI37267.1 - 0.026 14.8 0.1 0.044 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sensor PF13796.6 KPI37267.1 - 0.061 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative sensor DUF3042 PF11240.8 KPI37267.1 - 5.8 7.0 5.6 9.5 6.3 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) adh_short PF00106.25 KPI37268.1 - 3.1e-23 82.3 0.1 5e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37268.1 - 2.3e-14 53.5 0.1 3.2e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KPI37268.1 - 1.2e-06 28.6 0.1 1.5e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPI37268.1 - 0.0062 16.5 0.4 0.012 15.5 0.3 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPI37268.1 - 0.043 12.8 0.0 0.055 12.5 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPI37268.1 - 0.044 13.2 0.1 0.099 12.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sar8_2 PF03058.14 KPI37268.1 - 0.055 14.0 0.3 0.11 13.0 0.1 1.7 2 0 0 2 2 2 0 Sar8.2 family HD_5 PF13487.6 KPI37268.1 - 0.2 12.0 0.0 1 9.7 0.0 2.2 2 1 0 2 2 2 0 HD domain Pal1 PF08316.11 KPI37269.1 - 9e-49 165.8 0.4 9e-49 165.8 0.4 2.6 2 1 0 2 2 2 1 Pal1 cell morphology protein FSH1 PF03959.13 KPI37272.1 - 4.3e-26 91.9 0.0 5.7e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KPI37272.1 - 0.00083 20.0 1.8 0.0014 19.2 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Imm74 PF15603.6 KPI37272.1 - 0.0037 17.4 0.0 0.0099 16.1 0.0 1.7 2 0 0 2 2 2 1 Immunity protein 74 Abhydrolase_2 PF02230.16 KPI37272.1 - 0.007 16.2 0.1 0.03 14.1 0.1 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LtrA PF06772.11 KPI37273.1 - 1.5e-32 113.3 28.2 2.1e-32 112.7 28.2 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Popeye PF04831.13 KPI37273.1 - 2 8.6 6.5 9.4 6.4 0.8 2.6 2 0 0 2 2 2 0 Popeye protein conserved region SKG6 PF08693.10 KPI37274.1 - 0.058 12.8 0.1 0.18 11.2 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SSP160 PF06933.11 KPI37274.1 - 0.13 10.4 17.2 0.18 10.0 17.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Plasmodium_Vir PF05795.11 KPI37274.1 - 0.37 10.1 1.4 0.41 10.0 0.5 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Sporozoite_P67 PF05642.11 KPI37274.1 - 1.9 6.5 6.8 2 6.4 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prenylcys_lyase PF07156.14 KPI37275.1 - 1.9e-77 260.9 0.0 2.6e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KPI37275.1 - 4.7e-16 59.1 0.0 6.5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI37275.1 - 2.5e-11 43.6 0.0 5.8e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI37275.1 - 2.3e-08 34.0 0.0 2.2e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI37275.1 - 3e-05 23.4 0.0 0.0039 16.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI37275.1 - 5.4e-05 23.2 0.1 0.0029 17.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KPI37275.1 - 0.036 14.6 0.1 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI37275.1 - 0.056 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 KPI37275.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_GDSL_2 PF13472.6 KPI37276.1 - 4.9e-11 43.3 0.1 8.3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPI37276.1 - 0.00042 20.4 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Gar1 PF04410.14 KPI37278.1 - 2.2e-36 125.0 0.1 3.4e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region FlgT_C PF16538.5 KPI37278.1 - 0.066 13.7 1.6 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain PMSI1 PF15322.6 KPI37278.1 - 0.2 11.1 1.4 0.26 10.7 1.4 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative FoP_duplication PF13865.6 KPI37278.1 - 6.7 7.3 14.5 2 9.0 10.8 1.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Per1 PF04080.13 KPI37279.1 - 4.4e-92 308.4 16.5 9.2e-91 304.1 16.5 2.0 1 1 0 1 1 1 1 Per1-like family Glyco_hydro_3 PF00933.21 KPI37282.1 - 2.9e-34 118.9 0.0 4.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPI37282.1 - 1.2e-33 116.8 0.0 2.8e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPI37282.1 - 1.5e-10 41.0 0.0 3.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC1 PF03109.16 KPI37283.1 - 8.1e-34 116.3 0.0 1.8e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 ABC1 family GDH_N PF12466.8 KPI37283.1 - 0.044 14.0 3.3 0.23 11.7 3.1 2.4 1 1 0 1 1 1 0 Glutamate dehydrogenase N terminal MaoC_dehydratas PF01575.19 KPI37287.1 - 3.5e-25 88.0 0.0 6.6e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KPI37287.1 - 3.4e-06 27.2 0.0 0.0016 18.6 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase N_BRCA1_IG PF16158.5 KPI37288.1 - 1.1e-26 93.5 0.0 2.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KPI37288.1 - 1.9e-25 88.4 49.0 1.8e-11 43.6 7.1 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KPI37288.1 - 8.5e-06 26.0 45.6 0.027 14.8 7.9 4.7 4 0 0 4 4 4 4 C1 domain Terminase_3 PF04466.13 KPI37288.1 - 0.032 13.8 0.0 0.99 8.9 0.1 2.9 3 0 0 3 3 3 0 Phage terminase large subunit zf-dskA_traR PF01258.17 KPI37288.1 - 2.1 8.4 5.1 17 5.4 0.1 3.6 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger PP-binding PF00550.25 KPI37289.1 - 1.3e-10 41.4 0.2 1.8e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KPI37289.1 - 2.3e-06 27.7 0.3 3.5e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-carrier adh_short PF00106.25 KPI37291.1 - 5.9e-23 81.4 0.0 7.2e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37291.1 - 3.7e-19 69.2 0.0 5.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SHMT PF00464.19 KPI37291.1 - 0.11 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Fungal_trans PF04082.18 KPI37292.1 - 5.3e-10 38.8 0.0 8.9e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeobox_KN PF05920.11 KPI37294.1 - 2.7e-16 59.2 0.6 6.1e-16 58.0 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KPI37294.1 - 9.3e-06 25.6 0.1 2.3e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KPI37294.1 - 0.00028 20.7 0.2 0.00066 19.5 0.2 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KPI37294.1 - 0.0017 18.7 15.0 0.39 11.3 1.0 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI37294.1 - 0.0086 16.8 1.0 0.0086 16.8 1.0 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KPI37294.1 - 0.29 11.8 7.2 1 10.1 0.2 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn_clus PF00172.18 KPI37294.1 - 3.6 7.8 7.2 2.8e+02 1.7 7.2 2.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KPI37295.1 - 1e-78 265.2 19.6 1.2e-78 265.0 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37295.1 - 3.8e-18 65.5 20.6 3.8e-18 65.5 20.6 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily CrgA PF06781.12 KPI37295.1 - 2.3 8.3 6.6 2.4 8.3 0.0 3.8 4 0 0 4 4 4 0 Cell division protein CrgA Stm1_N PF09598.10 KPI37296.1 - 6.3e-17 62.2 4.8 6.3e-17 62.2 4.8 4.0 5 0 0 5 5 5 1 Stm1 mIF3 PF14877.6 KPI37296.1 - 0.11 12.1 0.6 0.17 11.6 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor SET PF00856.28 KPI37297.1 - 1.4e-21 77.6 0.0 7.3e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KPI37297.1 - 3.9e-06 27.6 0.6 3.9e-06 27.6 0.6 3.0 2 2 1 3 3 3 2 Rubisco LSMT substrate-binding DUF1045 PF06299.12 KPI37297.1 - 0.039 13.9 4.1 0.36 10.8 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1045) SepQ PF06622.11 KPI37297.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 SepQ protein RRM_1 PF00076.22 KPI37298.1 - 3.2e-18 65.3 0.0 1.3e-12 47.4 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI37298.1 - 0.0003 20.9 0.0 0.0023 18.0 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KPI37298.1 - 0.0023 17.9 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1934 PF09148.10 KPI37298.1 - 0.033 14.2 0.2 0.065 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1934) DUF4169 PF13770.6 KPI37298.1 - 0.045 14.0 1.4 0.045 14.0 1.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) G-alpha PF00503.20 KPI37300.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit 2OG-FeII_Oxy_2 PF13532.6 KPI37301.1 - 1.2e-35 123.5 0.0 1.8e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KPI37301.1 - 0.00014 21.9 7.9 0.0017 18.4 7.9 2.2 1 1 0 1 1 1 1 GRF zinc finger Btz PF09405.10 KPI37302.1 - 8.2e-21 74.6 4.0 2.1e-20 73.3 4.0 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding adh_short PF00106.25 KPI37304.1 - 9.6e-37 126.3 0.0 1.4e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37304.1 - 2.4e-21 76.4 0.0 3.9e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37304.1 - 4.6e-10 39.7 0.0 1.8e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI37304.1 - 0.0039 17.1 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 KPI37304.1 - 0.0067 15.8 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KPI37305.1 - 2.9e-21 76.1 0.0 3.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI37305.1 - 2.4e-07 30.8 0.0 2e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Peptidase_M28 PF04389.17 KPI37306.1 - 1.6e-42 145.4 0.1 2.4e-42 144.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KPI37306.1 - 4.6e-16 58.6 1.4 1e-15 57.5 1.4 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KPI37306.1 - 0.00096 18.9 0.0 0.0032 17.2 0.0 2.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HgmA PF04209.13 KPI37307.1 - 6.8e-125 417.1 0.2 8.7e-125 416.8 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sec39 PF08314.11 KPI37308.1 - 1.4e-155 519.8 7.7 6.9e-141 471.2 1.0 2.0 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Enolase_C PF00113.22 KPI37308.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain CoA_transf_3 PF02515.17 KPI37309.1 - 7.3e-108 361.0 0.0 2.5e-107 359.2 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III DUF5521 PF17659.1 KPI37309.1 - 0.025 12.5 5.2 0.055 11.3 5.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5521) LamB_YcsF PF03746.16 KPI37310.1 - 5.5e-66 222.7 0.0 3.2e-65 220.2 0.0 1.8 1 1 0 1 1 1 1 LamB/YcsF family Peptidase_S24 PF00717.23 KPI37311.1 - 7.2e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF3390 PF11870.8 KPI37311.1 - 0.024 15.0 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Sarcolipin PF05366.11 KPI37311.1 - 0.19 11.5 1.4 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Sarcolipin 4HBT PF03061.22 KPI37312.1 - 0.0026 18.1 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily EVE PF01878.18 KPI37313.1 - 6.7e-13 48.9 0.0 8.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 EVE domain Nmad3 PF18754.1 KPI37313.1 - 0.031 13.8 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 Nitroreductase PF00881.24 KPI37314.1 - 6.4e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family DUF1729 PF08354.10 KPI37315.1 - 0.027 13.4 0.8 0.033 13.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Co_AT_N PF12557.8 KPI37315.1 - 0.19 11.7 0.3 0.19 11.7 0.3 2.7 2 1 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal SNARE PF05739.19 KPI37316.1 - 2.3 8.3 3.8 5.7 7.0 0.1 3.1 3 0 0 3 3 3 0 SNARE domain NPV_P10 PF05531.12 KPI37316.1 - 6 7.4 11.3 2.5 8.6 1.5 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_trans_2 PF11951.8 KPI37317.1 - 8e-06 24.9 1.0 1.3e-05 24.2 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HWE_HK PF07536.14 KPI37317.1 - 0.052 14.3 0.5 0.16 12.7 0.5 1.8 1 0 0 1 1 1 0 HWE histidine kinase EPL1 PF10513.9 KPI37318.1 - 4.3e-19 69.4 0.1 4.3e-19 69.4 0.1 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like p450 PF00067.22 KPI37319.1 - 4.8e-61 206.9 0.0 6.5e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.16 KPI37320.1 - 3.7e-08 33.5 0.5 4.6e-08 33.2 0.5 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase UbiA PF01040.18 KPI37320.1 - 0.021 14.2 2.0 0.024 13.9 2.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family MIP PF00230.20 KPI37321.1 - 4.7e-31 108.3 7.5 6.2e-31 107.9 7.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ccdc124 PF06244.12 KPI37322.1 - 3.2e-21 76.2 19.9 1.3e-19 71.1 19.9 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 TPR_12 PF13424.6 KPI37323.1 - 3e-21 75.5 1.2 1.5e-10 41.2 0.0 4.6 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPI37323.1 - 1.6e-13 50.0 0.8 3.2e-05 23.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KPI37323.1 - 4.1e-09 36.0 0.0 7.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 KPI37323.1 - 7e-09 35.1 4.6 0.15 12.3 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI37323.1 - 1.7e-07 30.9 3.1 0.22 11.8 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPI37323.1 - 6.5e-07 29.8 0.1 0.0039 17.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPI37323.1 - 1.5e-06 28.5 1.1 6.6 7.8 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPI37323.1 - 2.1e-06 27.3 1.7 1.4 8.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI37323.1 - 9.5e-06 26.2 1.5 5 7.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KPI37323.1 - 0.00088 19.7 0.6 0.07 13.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KPI37323.1 - 0.002 17.6 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KPI37323.1 - 0.0045 16.9 0.9 8.6 6.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KPI37323.1 - 0.0051 17.2 0.2 0.031 14.7 0.0 2.6 3 1 0 3 3 2 1 AAA ATPase domain TPR_6 PF13174.6 KPI37323.1 - 0.0098 16.5 0.2 2.4 9.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPI37323.1 - 0.022 14.4 0.1 2.9 7.6 0.0 3.7 3 0 0 3 3 3 0 TPR repeat Resolvase PF00239.21 KPI37323.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_22 PF13401.6 KPI37323.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain BCS1_N PF08740.11 KPI37324.1 - 4.6e-25 88.7 0.5 3.5e-23 82.5 0.0 2.6 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KPI37324.1 - 1.1e-13 51.7 0.0 1.1e-05 25.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPI37324.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPI37324.1 - 0.0017 18.4 0.0 0.0059 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI37324.1 - 0.016 15.6 0.1 0.016 15.6 0.1 2.3 2 1 1 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 KPI37324.1 - 0.026 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KPI37324.1 - 0.027 14.2 4.5 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI37324.1 - 0.035 14.6 0.2 0.26 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPI37324.1 - 0.052 13.8 0.0 0.92 9.8 0.0 2.9 4 0 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 KPI37324.1 - 0.13 12.1 0.0 26 4.7 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KPI37324.1 - 0.25 11.5 2.1 2 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Med31 PF05669.12 KPI37327.1 - 2e-29 101.4 0.9 2.8e-29 100.9 0.9 1.2 1 0 0 1 1 1 1 SOH1 HlyIII PF03006.20 KPI37330.1 - 1.8e-55 188.1 17.6 2.2e-55 187.8 17.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Stealth_CR2 PF11380.8 KPI37330.1 - 0.18 12.0 0.3 4.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Stealth protein CR2, conserved region 2 Abhydrolase_1 PF00561.20 KPI37331.1 - 6.6e-09 35.8 0.0 4.9e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Muraidase PF11860.8 KPI37331.1 - 0.0024 18.1 0.2 0.011 15.9 0.2 2.0 1 1 0 1 1 1 1 N-acetylmuramidase Hydrolase_4 PF12146.8 KPI37331.1 - 0.023 13.9 0.0 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4440 PF14534.6 KPI37332.1 - 2.5e-08 34.3 0.0 3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Fungal_trans PF04082.18 KPI37334.1 - 5.1e-27 94.6 0.0 7.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTR2 PF00854.21 KPI37335.1 - 6.8e-74 249.1 9.8 9e-74 248.7 9.8 1.1 1 0 0 1 1 1 1 POT family Sugar_tr PF00083.24 KPI37335.1 - 0.00094 18.2 0.8 0.00094 18.2 0.8 3.3 4 0 0 4 4 4 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37335.1 - 0.0016 17.4 31.2 0.024 13.6 24.9 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3042 PF11240.8 KPI37335.1 - 0.11 12.6 0.1 5.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2627 PF11118.8 KPI37335.1 - 6.3 7.4 10.2 33 5.2 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) EI24 PF07264.11 KPI37336.1 - 1.4e-08 35.2 8.6 2.2e-08 34.5 8.6 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SH3_4 PF06347.13 KPI37336.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain XRCC4 PF06632.12 KPI37337.1 - 3.1e-08 32.9 15.4 5.4e-08 32.1 15.4 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 BPL_N PF09825.9 KPI37337.1 - 0.7 8.9 7.2 0.99 8.4 7.2 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Fungal_trans_2 PF11951.8 KPI37338.1 - 5e-06 25.6 0.9 1.2e-05 24.3 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain INO80_Ies4 PF08193.11 KPI37338.1 - 0.011 15.8 0.3 0.024 14.6 0.3 1.5 1 0 0 1 1 1 0 INO80 complex subunit Ies4 HAD_2 PF13419.6 KPI37339.1 - 3.9e-12 46.6 0.0 5.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI37339.1 - 4.4e-06 27.1 0.0 1.1e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI37339.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like LCAT PF02450.15 KPI37340.1 - 1.6e-91 307.4 0.1 2.1e-91 307.0 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1897 PF09005.10 KPI37341.1 - 0.041 13.4 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) cobW PF02492.19 KPI37342.1 - 5.8e-48 162.8 0.2 7.9e-48 162.4 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KPI37342.1 - 9.4e-06 25.6 0.1 0.043 13.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KPI37342.1 - 0.00043 20.4 0.0 0.00091 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI37342.1 - 0.00047 19.7 0.6 0.0024 17.4 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KPI37342.1 - 0.00076 20.0 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KPI37342.1 - 0.0011 18.8 0.4 0.01 15.6 0.4 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KPI37342.1 - 0.0018 18.7 0.0 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KPI37342.1 - 0.0096 16.4 0.1 0.043 14.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter CobW_C PF07683.14 KPI37342.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain ATPase_2 PF01637.18 KPI37342.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KPI37342.1 - 0.017 15.2 0.0 0.038 14.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KPI37342.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPI37342.1 - 0.019 14.7 0.1 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KPI37342.1 - 0.037 14.0 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 KPI37342.1 - 0.048 12.8 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MeaB PF03308.16 KPI37342.1 - 0.072 12.1 1.0 1 8.3 0.3 2.8 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KPI37342.1 - 0.086 13.1 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI37342.1 - 0.09 13.3 0.2 0.2 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI37342.1 - 0.091 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPI37342.1 - 0.1 12.7 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPI37342.1 - 0.11 11.7 0.1 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Pkinase PF00069.25 KPI37343.1 - 1.8e-75 253.7 0.0 2.7e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37343.1 - 5.3e-36 124.2 0.0 1.3e-35 122.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI37343.1 - 2.9e-06 26.8 0.6 1.2 8.4 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 KPI37343.1 - 0.0031 17.5 0.1 0.36 10.7 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPI37343.1 - 0.0031 16.3 0.2 0.022 13.6 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase MFS_1 PF07690.16 KPI37344.1 - 3.7e-15 55.7 7.0 3.7e-15 55.7 7.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily YtxH PF12732.7 KPI37344.1 - 0.28 11.7 2.0 1.5 9.4 2.0 2.2 1 1 0 1 1 1 0 YtxH-like protein EMP24_GP25L PF01105.24 KPI37345.1 - 5.2e-50 169.9 0.0 5.9e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD F_bP_aldolase PF01116.20 KPI37346.1 - 9.6e-85 284.4 0.0 1.1e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.18 KPI37346.1 - 0.015 14.8 0.0 0.06 12.8 0.0 2.0 3 0 0 3 3 3 0 Phosphotriesterase family KorB PF08535.10 KPI37346.1 - 0.088 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 KorB domain Fasciclin PF02469.22 KPI37347.1 - 9e-36 122.9 2.7 2.8e-19 69.6 0.6 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF3176 PF11374.8 KPI37348.1 - 0.053 13.7 1.1 0.12 12.6 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) Transferase PF02458.15 KPI37349.1 - 8.8e-10 37.8 0.0 2.9e-09 36.1 0.0 1.8 2 1 0 2 2 2 1 Transferase family PAF-AH_p_II PF03403.13 KPI37350.1 - 1e-38 132.8 0.0 3.3e-33 114.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KPI37350.1 - 2.6e-08 33.1 0.0 1.3e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KPI37350.1 - 3.7e-06 27.7 0.0 6.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37350.1 - 0.00028 20.2 0.1 0.048 12.9 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KPI37350.1 - 0.00054 19.1 0.0 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_3 PF07859.13 KPI37350.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KPI37350.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 KPI37350.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) HAUS6_N PF14661.6 KPI37351.1 - 6.3e-36 124.1 0.9 1.1e-35 123.3 0.9 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus SGL PF08450.12 KPI37352.1 - 1.4e-26 93.6 0.0 2.6e-26 92.7 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPI37352.1 - 0.00088 19.2 2.8 0.16 12.1 0.1 3.5 3 0 0 3 3 3 2 NHL repeat Arylesterase PF01731.20 KPI37352.1 - 0.016 15.4 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Acetyltransf_1 PF00583.25 KPI37353.1 - 4.7e-20 72.0 0.1 6.5e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPI37353.1 - 2.2e-11 43.6 0.0 3.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPI37353.1 - 3.6e-11 43.1 0.0 4.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI37353.1 - 1e-10 41.9 0.0 1.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPI37353.1 - 1.2e-08 35.7 0.0 1.5e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPI37353.1 - 9e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI37353.1 - 0.00016 21.8 0.0 0.0003 20.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KPI37353.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 KPI37353.1 - 0.0095 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 KPI37353.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IQ PF00612.27 KPI37354.1 - 0.0037 16.9 2.7 0.012 15.3 2.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Malate_DH PF12434.8 KPI37354.1 - 8.9 6.4 9.5 8.7 6.5 0.6 3.6 3 0 0 3 3 3 0 Malate dehydrogenase enzyme Catalase_C PF18011.1 KPI37355.1 - 0.062 12.9 0.2 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain found in long catalases BTB PF00651.31 KPI37356.1 - 1.1e-08 35.2 0.0 2.9e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain ADH_N PF08240.12 KPI37357.1 - 1e-23 83.3 1.0 2.5e-23 82.1 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI37357.1 - 1e-20 74.1 0.3 5.4e-20 71.7 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI37357.1 - 1.2e-08 36.1 0.0 2.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI37357.1 - 1e-05 25.2 0.1 1.7e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPI37357.1 - 0.015 14.6 0.1 0.031 13.6 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gti1_Pac2 PF09729.9 KPI37358.1 - 3.1e-38 131.7 2.9 2.8e-37 128.6 0.2 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family DUF3262 PF11660.8 KPI37359.1 - 0.0082 16.5 1.1 0.013 15.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3262) OppC_N PF12911.7 KPI37359.1 - 0.069 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FixQ PF05545.11 KPI37359.1 - 0.46 10.5 8.9 0.88 9.6 8.9 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ HNH PF01844.23 KPI37360.1 - 0.0058 16.8 2.0 0.014 15.6 2.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Zn_ribbon_2 PF12674.7 KPI37361.1 - 0.058 14.1 0.2 0.28 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain adh_short PF00106.25 KPI37362.1 - 8.9e-44 149.3 0.0 1.2e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37362.1 - 3.4e-30 105.3 0.0 4.3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37362.1 - 5.9e-10 39.3 0.0 8.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37362.1 - 4.9e-05 22.9 0.0 0.00011 21.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KPI37362.1 - 0.00027 20.4 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KPI37362.1 - 0.018 14.9 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Trm56 PF01994.16 KPI37362.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 GDP_Man_Dehyd PF16363.5 KPI37362.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPI37362.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_108 PF05838.12 KPI37362.1 - 0.17 12.4 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase 108 IU_nuc_hydro PF01156.19 KPI37364.1 - 9.5e-57 192.9 0.0 3.2e-56 191.1 0.0 1.7 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cutinase PF01083.22 KPI37365.1 - 1.6e-21 77.0 0.0 2.4e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Cutinase VIT1 PF01988.19 KPI37366.1 - 6.8e-63 212.4 1.5 7.7e-63 212.2 1.5 1.0 1 0 0 1 1 1 1 VIT family DUF3021 PF11457.8 KPI37366.1 - 0.12 12.7 3.8 0.36 11.2 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) FtsX PF02687.21 KPI37366.1 - 0.99 9.9 9.3 0.4 11.2 5.1 2.3 2 1 1 3 3 3 0 FtsX-like permease family SPW PF03779.14 KPI37366.1 - 1.6 8.3 0.0 1.6 8.3 0.0 3.4 3 0 0 3 3 3 0 SPW repeat SRPRB PF09439.10 KPI37367.1 - 2.1e-26 92.4 0.0 5.8e-25 87.8 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KPI37367.1 - 4.6e-08 32.7 0.0 0.0002 20.9 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPI37367.1 - 3.2e-07 30.4 0.0 5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI37367.1 - 2.2e-06 27.4 0.0 5.3e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI37367.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KPI37367.1 - 0.021 14.6 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KPI37367.1 - 0.026 14.9 0.1 0.046 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KPI37367.1 - 0.039 13.5 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KPI37367.1 - 0.056 13.5 0.0 1.6 8.7 0.0 2.3 1 1 0 2 2 2 0 Dynamin family Roc PF08477.13 KPI37367.1 - 0.076 13.2 0.0 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KPI37367.1 - 0.086 12.1 0.0 0.34 10.2 0.0 1.9 2 1 0 2 2 2 0 Septin AAA_22 PF13401.6 KPI37367.1 - 0.14 12.5 0.1 0.45 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 KPI37368.1 - 1.3e-12 47.7 0.1 5.2e-06 26.0 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KPI37368.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37368.1 - 0.02 15.1 0.0 0.064 13.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI37368.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI37368.1 - 0.14 11.4 0.0 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HD_3 PF13023.6 KPI37369.1 - 1.4e-47 161.7 0.0 1.9e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KPI37369.1 - 2.6e-11 43.6 0.0 3.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KPI37369.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.7 1 1 0 1 1 1 0 HD domain SCP2 PF02036.17 KPI37370.1 - 1.8e-23 82.9 0.3 2e-23 82.8 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KPI37370.1 - 1.8e-06 28.2 0.1 2.1e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KPI37370.1 - 0.089 13.2 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain MFS_1 PF07690.16 KPI37372.1 - 1.3e-43 149.3 40.7 4.3e-43 147.6 39.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI37372.1 - 6.4e-14 51.7 4.8 6.4e-14 51.7 4.8 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter DUF755 PF05501.11 KPI37372.1 - 2.2 8.6 9.9 4.7 7.5 9.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PAP2 PF01569.21 KPI37372.1 - 4.2 7.1 15.0 2.1 8.1 3.1 3.5 2 1 1 3 3 3 0 PAP2 superfamily Palm_thioest PF02089.15 KPI37373.1 - 1.9e-07 31.2 0.0 3.5e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KPI37373.1 - 6.4e-06 26.9 0.6 8.4e-06 26.5 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KPI37373.1 - 2.4e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KPI37373.1 - 4.2e-05 23.2 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KPI37373.1 - 0.00023 20.9 0.2 0.00092 18.9 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 KPI37373.1 - 0.00079 18.7 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KPI37373.1 - 0.0026 17.2 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KPI37373.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PAS_3 PF08447.12 KPI37374.1 - 1.4e-11 44.5 0.0 7.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KPI37374.1 - 6.8e-07 29.5 0.0 0.0019 18.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KPI37374.1 - 1.4e-05 25.3 0.0 0.014 15.7 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KPI37374.1 - 2.1e-05 24.5 0.0 0.055 13.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KPI37374.1 - 2.9e-05 24.1 0.0 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 KPI37374.1 - 0.1 12.2 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain HTH_32 PF13565.6 KPI37375.1 - 8.1e-05 23.2 10.4 0.027 15.1 0.5 2.4 1 1 1 2 2 2 2 Homeodomain-like domain DNA_meth_N PF18284.1 KPI37375.1 - 0.00018 21.3 0.1 0.67 9.9 0.0 3.0 3 0 0 3 3 3 2 DNA methylase N-terminal domain Myb_DNA-binding PF00249.31 KPI37375.1 - 0.0064 16.7 0.1 5.8 7.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_WhiA PF02650.14 KPI37375.1 - 0.017 15.4 0.0 5.7 7.4 0.0 2.5 1 1 1 2 2 2 0 WhiA C-terminal HTH domain HTH_24 PF13412.6 KPI37375.1 - 0.021 14.4 0.0 11 5.6 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding EthD PF07110.11 KPI37376.1 - 0.00077 20.6 1.2 0.49 11.6 0.2 2.9 2 2 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KPI37376.1 - 0.0091 16.5 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Acyltransferase PF01553.21 KPI37377.1 - 0.003 17.2 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF2321 PF10083.9 KPI37379.1 - 0.071 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) NB-ARC PF00931.22 KPI37380.1 - 7.8e-07 28.5 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KPI37380.1 - 8.7e-05 23.0 0.1 0.00044 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PGAP1 PF07819.13 KPI37380.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.6 KPI37380.1 - 0.0033 17.7 0.0 0.0098 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KPI37380.1 - 0.015 15.2 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain DUF676 PF05057.14 KPI37380.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) TsaE PF02367.17 KPI37380.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KPI37380.1 - 0.21 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 KPI37381.1 - 2.2e-39 135.4 0.0 3.5e-22 79.0 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37381.1 - 3.1e-14 52.9 0.2 2.2e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI37381.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase adh_short PF00106.25 KPI37382.1 - 5.4e-37 127.1 0.0 7.6e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37382.1 - 3.1e-20 72.8 0.0 4.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37382.1 - 2.5e-07 30.8 0.1 4.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPI37382.1 - 0.035 14.0 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KH_8 PF17903.1 KPI37384.1 - 3.8e-29 100.6 0.0 8.4e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain EthD PF07110.11 KPI37385.1 - 6.2e-16 59.3 0.1 7.9e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPI37385.1 - 6e-09 36.4 0.1 7.5e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF659 PF04937.15 KPI37385.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) ATP-grasp PF02222.22 KPI37385.1 - 0.025 14.1 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain DltD PF04914.12 KPI37385.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 DltD protein BAR_2 PF10455.9 KPI37386.1 - 5.1e-43 147.3 6.0 1.2e-41 142.7 6.0 2.2 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KPI37386.1 - 2.9e-13 50.0 7.4 3.7e-08 33.3 2.8 2.2 2 0 0 2 2 2 2 BAR domain TetR_C_24 PF17932.1 KPI37386.1 - 0.4 11.0 1.8 4.5 7.6 0.2 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SURF4 PF02077.15 KPI37387.1 - 5.1e-86 288.6 6.9 5.9e-86 288.4 6.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0029 PF01205.19 KPI37388.1 - 5.4e-30 103.8 0.0 7.9e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KPI37388.1 - 7.3e-07 29.5 0.0 1.7e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.26 KPI37388.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme SH3_16 PF18348.1 KPI37389.1 - 0.074 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Peptidase_M76 PF09768.9 KPI37390.1 - 9.8e-63 211.0 3.6 1.2e-62 210.7 3.6 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KPI37390.1 - 4.3e-05 23.3 0.3 8.7e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KPI37390.1 - 0.0063 16.9 0.0 0.0096 16.3 0.0 1.2 1 0 0 1 1 1 1 Effector protein DUF2268 PF10026.9 KPI37390.1 - 0.073 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DA1-like PF12315.8 KPI37390.1 - 0.075 12.4 0.5 0.13 11.6 0.5 1.5 1 1 0 1 1 1 0 Protein DA1 HET PF06985.11 KPI37392.1 - 2.2e-30 105.9 0.0 3.4e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2781 PF10914.8 KPI37393.1 - 4.9e-32 111.4 13.2 5.5e-32 111.2 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) NPR3 PF03666.13 KPI37394.1 - 0.27 10.0 0.1 0.38 9.5 0.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Kelch_4 PF13418.6 KPI37395.1 - 2.8e-12 46.4 17.1 1.2e-07 31.6 0.0 5.1 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KPI37395.1 - 3.1e-11 43.0 0.6 0.0081 16.1 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KPI37395.1 - 3e-10 40.0 10.4 0.0021 18.3 0.1 5.1 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KPI37395.1 - 3.2e-08 33.0 0.4 0.0039 16.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KPI37395.1 - 3.4e-08 33.6 19.4 0.0044 17.3 0.2 6.2 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KPI37395.1 - 6.2e-05 22.8 8.7 0.031 14.3 0.1 5.2 5 1 0 5 5 5 2 Kelch motif MIT PF04212.18 KPI37396.1 - 1.6e-13 50.5 1.9 2.5e-13 49.9 1.9 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cu-oxidase_3 PF07732.15 KPI37397.1 - 1.2e-33 115.7 4.1 2.1e-33 114.8 3.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPI37397.1 - 2e-33 115.0 0.2 2e-33 115.0 0.2 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KPI37397.1 - 1.5e-22 80.4 0.2 4.3e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Presenilin PF01080.17 KPI37398.1 - 4.4 6.0 21.3 2.6 6.7 6.2 2.3 2 0 0 2 2 2 0 Presenilin ECM11 PF15463.6 KPI37399.1 - 1e-29 103.8 5.3 1e-29 103.8 5.3 1.9 2 0 0 2 2 2 1 Extracellular mutant protein 11 XPG_I_2 PF12813.7 KPI37400.1 - 2.6e-49 168.0 0.0 3.8e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KPI37400.1 - 0.012 16.0 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 XPG I-region PUF PF00806.19 KPI37401.1 - 1.8e-16 58.8 0.0 0.00035 20.1 0.1 7.2 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Erg28 PF03694.13 KPI37402.1 - 5.5e-30 104.0 0.0 7.6e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Erg28 like protein Flavin_Reduct PF01613.18 KPI37403.1 - 1.7e-17 63.9 0.0 2.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain LEA_4 PF02987.16 KPI37404.1 - 0.29 11.3 22.0 0.13 12.4 13.9 3.0 2 1 1 3 3 3 0 Late embryogenesis abundant protein CsbD PF05532.12 KPI37404.1 - 1.6 8.7 22.1 0.1 12.5 11.6 2.8 2 1 1 3 3 3 0 CsbD-like SANT_DAMP1_like PF16282.5 KPI37405.1 - 1.4e-23 82.8 1.4 2.4e-23 82.1 1.4 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 KPI37405.1 - 0.03 14.6 0.0 0.098 12.9 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KPI37405.1 - 0.19 11.9 2.1 1.3 9.3 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2247 PF10004.9 KPI37405.1 - 0.99 9.2 6.5 1.1 9.0 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) MFS_1 PF07690.16 KPI37406.1 - 2.5e-27 95.7 28.4 1.2e-26 93.5 29.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_17 PF00332.18 KPI37407.1 - 0.022 14.4 0.1 0.034 13.7 0.1 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 17 adh_short PF00106.25 KPI37408.1 - 1.6e-43 148.4 0.0 2.2e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37408.1 - 1.2e-40 139.6 0.0 1.9e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI37408.1 - 0.0002 20.9 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI37408.1 - 0.0027 17.7 0.2 0.026 14.5 0.1 2.4 2 1 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KPI37408.1 - 0.0099 15.8 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPI37408.1 - 0.02 13.6 0.1 0.026 13.2 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Glyco_trans_4_2 PF13477.6 KPI37408.1 - 0.039 14.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like GDP_Man_Dehyd PF16363.5 KPI37408.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF973 PF06157.11 KPI37409.1 - 0.71 8.9 6.2 0.92 8.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Metallophos PF00149.28 KPI37411.1 - 1.9e-12 48.1 1.0 4.9e-12 46.8 1.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI37411.1 - 4.8e-08 33.4 0.0 3.2e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GM_CSF PF01109.17 KPI37412.1 - 0.26 11.4 0.5 0.76 9.9 0.0 1.8 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor CAP_GLY PF01302.25 KPI37413.1 - 2e-15 56.5 0.7 3.7e-15 55.7 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KPI37413.1 - 2.2e-09 37.0 10.1 5.3e-05 23.0 2.2 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF812 PF05667.11 KPI37413.1 - 0.00032 19.7 15.3 0.00032 19.7 15.3 3.2 1 1 1 2 2 1 1 Protein of unknown function (DUF812) Pkip-1 PF06878.11 KPI37413.1 - 0.12 12.5 2.1 0.41 10.7 2.1 1.8 1 0 0 1 1 1 0 Pkip-1 protein APG6_N PF17675.1 KPI37413.1 - 0.14 12.6 39.0 0.026 15.1 4.4 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region YabA PF06156.13 KPI37413.1 - 0.3 11.7 0.1 0.3 11.7 0.1 4.9 3 1 1 4 4 4 0 Initiation control protein YabA Spc7 PF08317.11 KPI37413.1 - 1 8.2 37.5 2.5 6.9 3.5 4.0 2 1 2 4 4 4 0 Spc7 kinetochore protein Borrelia_REV PF03978.13 KPI37413.1 - 2.2 8.2 5.3 0.44 10.5 0.4 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF1664 PF07889.12 KPI37413.1 - 2.4 8.2 16.8 0.13 12.3 3.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KPI37413.1 - 3.2 8.1 26.6 0.26 11.6 4.6 4.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KPI37413.1 - 7.7 7.1 24.1 0.06 13.8 1.2 4.6 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.10 KPI37413.1 - 8.7 6.7 35.6 5.3 7.4 1.7 5.0 2 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) Tn7_Tnp_TnsA_C PF08721.11 KPI37413.1 - 9.8 6.9 6.0 3.5 8.3 0.2 3.2 3 0 0 3 3 3 0 TnsA endonuclease C terminal Fib_alpha PF08702.10 KPI37413.1 - 10 6.3 23.6 12 6.1 4.2 4.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Fungal_trans_2 PF11951.8 KPI37414.1 - 2.5e-12 46.3 2.8 2.7e-12 46.2 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37414.1 - 2.7e-08 33.8 11.5 4.7e-08 33.0 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thaumatin PF00314.17 KPI37415.1 - 6.6e-34 117.4 0.1 1e-33 116.8 0.1 1.3 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KPI37415.1 - 0.00015 21.2 0.1 0.023 14.0 0.0 2.1 2 0 0 2 2 2 2 Beta-1,3-glucanase Hva1_TUDOR PF11160.8 KPI37416.1 - 2.5e-15 56.4 0.6 2.5e-15 56.4 0.6 3.1 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Amidase PF01425.21 KPI37417.1 - 3e-57 194.6 0.0 3.4e-50 171.3 0.1 2.2 2 0 0 2 2 2 2 Amidase Nucleoporin_N PF08801.11 KPI37419.1 - 1.3e-85 287.7 0.1 1.8e-85 287.3 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KPI37419.1 - 4.8e-54 184.1 0.5 7.2e-54 183.5 0.5 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Fungal_lectin PF07938.12 KPI37419.1 - 0.013 15.0 0.0 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 Fungal fucose-specific lectin PET117 PF15786.5 KPI37420.1 - 8.1e-26 90.1 2.7 9.2e-26 89.9 2.7 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial COX16 PF14138.6 KPI37420.1 - 0.048 14.2 0.3 0.062 13.8 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 APH PF01636.23 KPI37421.1 - 1.1e-32 113.9 0.0 2e-32 113.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KPI37421.1 - 0.00046 19.6 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase RIO1 PF01163.22 KPI37421.1 - 0.016 14.9 0.0 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Epimerase PF01370.21 KPI37423.1 - 3.7e-09 36.4 0.1 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPI37423.1 - 1.7e-05 25.2 0.0 3.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KPI37423.1 - 9.2e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPI37423.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPI37423.1 - 0.096 11.8 0.0 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein GalP_UDP_transf PF01087.22 KPI37426.1 - 3.6e-67 226.4 0.1 1.8e-65 220.8 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KPI37426.1 - 1.3e-57 194.2 0.2 3.2e-57 192.9 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KPI37426.1 - 0.00016 22.3 0.0 0.0016 19.2 0.0 2.3 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 KPI37426.1 - 0.00042 19.2 0.1 0.031 13.1 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4921) DcpS_C PF11969.8 KPI37426.1 - 0.019 15.4 0.0 0.069 13.6 0.0 1.9 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Sugar_tr PF00083.24 KPI37427.1 - 1.4e-131 439.5 22.5 1.6e-131 439.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37427.1 - 1.1e-31 110.1 48.8 2e-26 92.8 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.12 KPI37427.1 - 0.2 11.7 2.6 2.1 8.5 0.1 2.6 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB AA_permease_2 PF13520.6 KPI37428.1 - 6.1e-37 127.5 36.0 8.2e-32 110.6 24.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPI37428.1 - 6.1e-12 44.9 23.1 6.1e-12 44.9 23.1 1.9 1 1 1 2 2 2 1 Amino acid permease MFS_1 PF07690.16 KPI37429.1 - 4.3e-30 104.8 35.8 1.2e-26 93.5 14.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI37429.1 - 0.00014 20.8 2.7 0.0013 17.7 0.0 2.4 2 1 0 2 2 2 2 MFS_1 like family BT1 PF03092.16 KPI37429.1 - 0.0069 14.7 7.5 0.033 12.4 0.2 2.8 2 1 0 3 3 3 2 BT1 family GCP_C_terminal PF04130.13 KPI37430.1 - 1.6e-89 300.5 1.8 2.6e-89 299.8 1.8 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KPI37430.1 - 1.6e-73 248.1 0.0 3.6e-73 246.9 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal 4HBT PF03061.22 KPI37431.1 - 1.9e-08 34.6 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KPI37431.1 - 7.5e-06 26.4 0.0 9.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 KPI37431.1 - 0.011 16.3 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 KPI37431.1 - 0.05 13.7 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) zf-CCCH PF00642.24 KPI37433.1 - 2.8e-08 33.5 19.3 3.9e-07 29.8 2.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KPI37433.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KPI37433.1 - 0.0036 18.0 1.5 0.51 11.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KPI37433.1 - 0.0049 16.9 3.3 0.0049 16.9 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain DUF2213 PF09979.9 KPI37434.1 - 0.098 12.6 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) AA_permease PF00324.21 KPI37436.1 - 1.2e-68 231.9 42.4 1.5e-67 228.3 42.4 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI37436.1 - 1.3e-23 83.6 36.0 1.7e-23 83.2 36.0 1.2 1 0 0 1 1 1 1 Amino acid permease UCR_6-4kD PF08997.10 KPI37436.1 - 0.14 12.1 1.8 0.53 10.3 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Peptidase_S9 PF00326.21 KPI37437.1 - 8.7e-40 136.4 0.4 1e-31 110.1 0.2 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family PD40 PF07676.12 KPI37437.1 - 0.00015 21.6 5.5 0.013 15.4 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 KPI37437.1 - 0.065 11.9 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KPI37437.1 - 0.072 12.7 0.6 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Putative esterase PPR_2 PF13041.6 KPI37438.1 - 0.0037 17.4 0.1 0.6 10.3 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family RNA_pol_I_A49 PF06870.12 KPI37438.1 - 0.14 11.0 1.3 0.22 10.4 0.2 1.7 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor PWWP PF00855.17 KPI37439.1 - 3.7e-14 52.9 0.0 3.7e-14 52.9 0.0 3.1 2 1 1 3 3 3 1 PWWP domain DNA_mis_repair PF01119.19 KPI37439.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Rad60-SLD PF11976.8 KPI37439.1 - 0.06 13.2 0.2 0.19 11.5 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like KRE9 PF05390.11 KPI37440.1 - 2.8e-15 56.9 5.2 2.8e-15 56.9 5.2 2.1 2 1 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 PAP2_3 PF14378.6 KPI37441.1 - 1.9e-30 106.0 22.1 5.5e-17 62.1 0.2 3.5 4 0 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.21 KPI37441.1 - 0.0074 16.1 1.6 0.0074 16.1 1.6 2.7 2 1 0 2 2 2 1 PAP2 superfamily SpvB PF03534.13 KPI37441.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Kinesin PF00225.23 KPI37443.1 - 1.9e-99 332.7 2.8 4.2e-99 331.6 2.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPI37443.1 - 3.3e-58 195.9 0.1 8.1e-58 194.6 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding Rho_Binding PF08912.11 KPI37443.1 - 0.049 14.4 1.0 0.049 14.4 1.0 4.8 2 1 2 4 4 4 0 Rho Binding AAA_16 PF13191.6 KPI37443.1 - 0.23 11.8 3.8 0.95 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain HIP1_clath_bdg PF16515.5 KPI37443.1 - 7.9 7.2 43.2 0.066 13.8 10.9 5.1 1 1 5 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FA_hydroxylase PF04116.13 KPI37444.1 - 1.4e-27 96.7 18.8 3.3e-27 95.4 18.8 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ribonuc_L-PSP PF01042.21 KPI37445.1 - 2.3e-14 53.4 0.0 3.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pyridoxal_deC PF00282.19 KPI37446.1 - 8.7e-67 225.4 0.0 2.7e-65 220.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KPI37446.1 - 7.2e-05 21.9 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPI37446.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ribosomal_L5_C PF00673.21 KPI37446.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Arf PF00025.21 KPI37448.1 - 1.4e-58 197.2 0.4 1.6e-46 158.0 0.1 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KPI37448.1 - 2.7e-13 50.2 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KPI37448.1 - 8.4e-11 41.6 0.2 8.3e-07 28.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KPI37448.1 - 2.9e-08 33.4 0.0 8.2e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KPI37448.1 - 4.8e-07 29.5 0.0 1.4e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KPI37448.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPI37448.1 - 4.6e-06 26.2 0.0 7.4e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KPI37448.1 - 0.0045 16.5 0.0 0.072 12.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KPI37448.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KPI37448.1 - 0.1 12.1 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B CBFD_NFYB_HMF PF00808.23 KPI37449.1 - 4.5e-14 52.5 0.8 6.9e-14 51.9 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPI37449.1 - 0.00083 19.7 0.5 0.00083 19.7 0.5 2.0 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PAP_central PF04928.17 KPI37450.1 - 1.8e-103 344.9 0.0 2.2e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KPI37450.1 - 1.3e-41 142.1 0.0 4.4e-41 140.4 0.0 1.9 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KPI37450.1 - 7.2e-10 39.0 0.0 1.7e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KPI37450.1 - 0.18 11.6 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Lactonase PF10282.9 KPI37451.1 - 0.067 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller NOA36 PF06524.12 KPI37451.1 - 0.61 9.4 3.4 0.74 9.1 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein ECH_1 PF00378.20 KPI37452.1 - 6.3e-38 130.5 0.0 1.3e-37 129.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI37452.1 - 6e-25 88.5 0.0 7.1e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Keratin_2_head PF16208.5 KPI37453.1 - 0.25 11.5 9.5 0.38 10.9 9.5 1.2 1 0 0 1 1 1 0 Keratin type II head DUF3482 PF11981.8 KPI37453.1 - 0.54 9.6 14.3 2.1 7.7 14.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_OmpA PF13436.6 KPI37453.1 - 6.7 6.6 28.8 2.4 8.0 15.0 2.6 1 1 1 2 2 2 0 Glycine-zipper domain TraT PF05818.12 KPI37453.1 - 7.7 6.1 11.0 16 5.1 10.9 1.8 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Mob1_phocein PF03637.17 KPI37454.1 - 4.3e-21 75.7 0.0 7.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family Phage_holin_3_6 PF07332.11 KPI37455.1 - 0.012 15.6 2.8 0.012 15.6 2.8 4.4 4 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 KPI37455.1 - 2.6 8.6 4.3 3.2 8.3 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_M28 PF04389.17 KPI37456.1 - 1e-29 103.7 0.0 1.6e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPI37456.1 - 4.9e-06 26.4 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AA_permease PF00324.21 KPI37457.1 - 3.7e-103 345.7 41.9 4.3e-103 345.5 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI37457.1 - 3.8e-28 98.5 45.9 4.9e-28 98.1 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 KPI37458.1 - 7.5e-19 68.4 0.0 9.9e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPI37458.1 - 1.5e-12 47.1 0.0 3.3e-12 46.0 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase p450 PF00067.22 KPI37459.1 - 9e-27 93.9 0.9 4e-22 78.6 0.1 2.9 2 2 0 2 2 2 2 Cytochrome P450 Alpha-amylase PF00128.24 KPI37460.1 - 7.9e-38 130.9 0.0 1.4e-34 120.2 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPI37460.1 - 0.0046 16.1 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KPI37460.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) OmpH PF03938.14 KPI37460.1 - 0.21 11.9 1.1 0.5 10.7 0.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Hamartin PF04388.12 KPI37460.1 - 0.81 8.3 8.2 1.4 7.5 8.2 1.3 1 0 0 1 1 1 0 Hamartin protein YqeY PF09424.10 KPI37461.1 - 2.4e-14 53.6 3.4 3.1e-14 53.2 3.4 1.2 1 0 0 1 1 1 1 Yqey-like protein Pil1 PF13805.6 KPI37461.1 - 0.027 14.0 1.3 0.033 13.7 1.3 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 FAD_binding_3 PF01494.19 KPI37462.1 - 1.7e-14 53.9 0.5 3e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI37462.1 - 4.2e-08 32.8 0.1 9.1e-08 31.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI37462.1 - 6.3e-08 32.6 0.1 9.2e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37462.1 - 5.1e-07 29.8 1.0 1.2e-06 28.7 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI37462.1 - 1e-05 26.0 1.0 4.7e-05 23.9 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI37462.1 - 0.00014 21.1 1.3 0.00022 20.4 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI37462.1 - 0.0046 15.7 1.0 0.0072 15.1 1.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KPI37462.1 - 0.0048 16.3 1.7 0.0098 15.3 1.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KPI37462.1 - 0.0064 15.6 0.6 0.012 14.7 0.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KPI37462.1 - 0.037 13.1 0.6 0.086 11.9 0.6 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KPI37462.1 - 0.045 13.6 0.3 0.045 13.6 0.3 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KPI37462.1 - 0.051 13.6 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.24 KPI37462.1 - 0.053 12.8 0.1 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KPI37462.1 - 0.056 12.7 2.2 0.066 12.5 0.1 2.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI37462.1 - 0.21 10.4 1.4 2 7.2 0.8 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.24 KPI37463.1 - 1e-98 331.2 27.4 7.6e-57 193.2 2.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI37463.1 - 2.9e-23 82.4 36.6 3.4e-15 55.8 12.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KPI37463.1 - 0.0045 15.3 0.8 0.011 14.0 0.2 1.9 2 0 0 2 2 2 1 BT1 family Phage_holin_3_2 PF04550.12 KPI37463.1 - 1 9.9 4.5 0.65 10.6 1.4 2.3 2 0 0 2 2 2 0 Phage holin family 2 FAD_binding_4 PF01565.23 KPI37464.1 - 2.5e-15 56.4 0.0 4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ERAP1_C PF11838.8 KPI37465.1 - 1.2e-84 284.6 0.3 2.3e-84 283.6 0.3 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KPI37465.1 - 3.6e-83 278.4 4.0 3.7e-83 278.4 2.6 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KPI37465.1 - 5.5e-43 147.3 0.1 7.7e-42 143.6 0.1 2.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KPI37465.1 - 0.0039 17.2 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) RNase_H2-Ydr279 PF09468.10 KPI37465.1 - 0.11 12.6 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ATP12 PF07542.11 KPI37466.1 - 3.2e-42 143.7 0.1 9.9e-42 142.1 0.0 1.9 2 0 0 2 2 1 1 ATP12 chaperone protein Pyr_redox_3 PF13738.6 KPI37466.1 - 3e-16 59.5 0.0 1.7e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI37466.1 - 4.3e-14 51.8 0.0 3.8e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI37466.1 - 6.3e-12 45.3 0.0 2.3e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI37466.1 - 1.4e-09 38.3 1.1 0.019 15.5 0.0 3.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI37466.1 - 1.5e-09 37.5 0.1 4.3e-06 26.1 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPI37466.1 - 5.9e-09 36.0 4.2 0.0024 17.5 0.1 4.4 2 2 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI37466.1 - 1.6e-07 30.4 0.9 0.0011 17.8 0.1 3.2 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 KPI37466.1 - 1.9e-07 31.2 0.2 1.4e-05 25.2 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI37466.1 - 5.5e-06 25.7 3.9 0.011 14.9 0.0 3.9 5 0 0 5 5 5 2 FAD binding domain NAD_binding_9 PF13454.6 KPI37466.1 - 1.8e-05 24.8 3.4 0.051 13.6 0.7 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KPI37466.1 - 3.2e-05 24.0 0.5 0.0018 18.3 0.0 2.7 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KPI37466.1 - 0.00011 22.4 0.1 0.51 10.6 0.0 2.9 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.17 KPI37466.1 - 0.00014 21.2 0.2 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KPI37466.1 - 0.00027 20.3 0.9 0.0077 15.5 0.1 2.7 2 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KPI37466.1 - 0.00043 19.7 0.0 0.73 9.0 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 KPI37466.1 - 0.0016 17.6 1.3 1.1 8.3 0.1 3.2 3 1 0 3 3 3 1 Glucose inhibited division protein A F420_oxidored PF03807.17 KPI37466.1 - 0.0052 17.3 0.0 1.2 9.7 0.0 2.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPI37466.1 - 0.018 14.4 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KPI37466.1 - 0.028 13.3 0.7 1.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase UnbV_ASPIC PF07593.12 KPI37466.1 - 0.042 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 ASPIC and UnbV FAD_oxidored PF12831.7 KPI37466.1 - 0.046 13.1 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KPI37466.1 - 0.052 14.0 0.0 1.4 9.4 0.0 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KPI37466.1 - 0.077 12.0 0.1 1.5 7.8 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein IlvN PF07991.12 KPI37466.1 - 0.13 11.8 0.4 8.2 6.0 0.1 2.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KPI37466.1 - 0.17 12.2 0.4 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FHA PF00498.26 KPI37467.1 - 5.4e-14 52.3 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPI37467.1 - 0.0012 19.1 0.1 0.033 14.5 0.1 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Methyltransf_23 PF13489.6 KPI37468.1 - 1.9e-10 40.8 0.1 7.6e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI37468.1 - 2.5e-06 28.1 0.0 8.4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI37468.1 - 5.7e-06 26.9 0.0 1.8e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI37468.1 - 5.4e-05 23.9 0.0 0.00019 22.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KPI37468.1 - 0.055 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NTF2 PF02136.20 KPI37468.1 - 0.19 12.3 0.0 0.36 11.4 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain zf-AN1 PF01428.16 KPI37469.1 - 4.6e-23 81.1 27.5 1.2e-11 44.6 11.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KPI37469.1 - 0.0099 16.1 15.7 0.1 12.9 5.0 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KPI37469.1 - 0.024 15.0 13.6 0.07 13.5 3.7 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-PHD-like PF15446.6 KPI37469.1 - 0.056 13.1 11.0 0.69 9.5 1.6 2.3 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Remorin_C PF03763.13 KPI37469.1 - 0.089 12.7 2.7 0.16 11.8 2.7 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region C1_4 PF07975.12 KPI37469.1 - 0.94 9.8 21.3 6.2 7.1 3.0 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Pyr_redox_2 PF07992.14 KPI37472.1 - 1.9e-14 53.6 0.0 9.6e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI37472.1 - 5e-07 29.1 0.0 0.0019 17.4 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 KPI37472.1 - 2.5e-05 24.0 0.2 0.022 14.4 0.3 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI37472.1 - 0.00063 19.1 0.1 1.2 8.3 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI37472.1 - 0.00077 18.6 0.0 0.19 10.8 0.1 3.1 2 1 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPI37472.1 - 0.0022 17.3 0.4 0.004 16.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI37472.1 - 0.0058 15.4 0.0 0.094 11.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPI37472.1 - 0.014 14.7 0.1 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1681 PF07933.14 KPI37472.1 - 0.032 13.9 0.0 9.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Thi4 PF01946.17 KPI37472.1 - 0.034 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KPI37472.1 - 0.17 12.2 0.2 0.54 10.5 0.2 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KPI37472.1 - 0.19 10.5 0.1 0.27 10.0 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KPI37472.1 - 0.22 10.6 0.0 1.6 7.8 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Alpha-amylase PF00128.24 KPI37474.1 - 2.6e-22 79.8 0.1 4.3e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KPI37474.1 - 0.0017 18.5 0.2 0.0041 17.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KPI37474.1 - 0.0029 15.9 0.0 0.16 10.1 0.0 2.7 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 Thymidylat_synt PF00303.19 KPI37475.1 - 5.3e-104 347.1 0.0 6.2e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Vma12 PF11712.8 KPI37476.1 - 0.02 15.0 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Fungal_trans_2 PF11951.8 KPI37477.1 - 8.6e-06 24.8 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.7 KPI37478.1 - 0.0001 22.1 0.1 0.00025 20.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI37478.1 - 0.00016 21.4 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KPI37478.1 - 0.62 10.0 2.6 1.7 8.6 0.1 2.5 2 1 1 3 3 3 0 F-box Abhydrolase_1 PF00561.20 KPI37479.1 - 8.5e-17 61.6 0.0 1.5e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37479.1 - 1.7e-14 54.9 0.0 2.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37479.1 - 0.0012 18.1 0.1 0.0024 17.2 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KPI37479.1 - 0.0052 15.8 0.2 0.027 13.5 0.0 2.1 2 1 0 2 2 2 1 Chlorophyllase Ndr PF03096.14 KPI37479.1 - 0.16 10.6 0.0 1.8 7.2 0.0 2.0 2 0 0 2 2 2 0 Ndr family adh_short_C2 PF13561.6 KPI37480.1 - 7.8e-53 179.4 3.4 9.1e-53 179.2 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI37480.1 - 6.8e-39 133.3 1.6 8.3e-39 133.1 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI37480.1 - 1.5e-09 38.1 0.7 2.1e-09 37.6 0.7 1.2 1 0 0 1 1 1 1 KR domain Polysacc_deac_1 PF01522.21 KPI37481.1 - 4.7e-18 65.3 0.0 6.1e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KPI37481.1 - 0.045 12.9 0.0 0.096 11.9 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Ras PF00071.22 KPI37483.1 - 2e-60 203.1 0.3 3.2e-60 202.4 0.3 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI37483.1 - 2.1e-30 105.4 0.1 5.8e-30 104.0 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI37483.1 - 2.1e-13 50.1 0.1 3.6e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI37483.1 - 0.00076 19.1 0.2 0.0019 17.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPI37483.1 - 0.017 15.2 0.0 0.1 12.7 0.0 2.2 1 1 1 2 2 2 0 50S ribosome-binding GTPase DUF1691 PF07950.11 KPI37484.1 - 8.4e-35 119.7 2.8 3e-26 92.2 1.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) AAA_13 PF13166.6 KPI37486.1 - 0.11 11.2 1.9 0.15 10.7 1.9 1.1 1 0 0 1 1 1 0 AAA domain DUF2937 PF11157.8 KPI37486.1 - 0.37 10.5 0.7 0.63 9.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MFS_1 PF07690.16 KPI37488.1 - 1.7e-10 40.4 15.8 1.7e-10 40.4 15.8 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI37488.1 - 6.7e-06 25.2 5.0 6.7e-06 25.2 5.0 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter F-box-like PF12937.7 KPI37489.1 - 8.8e-06 25.5 0.5 1.7e-05 24.6 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KPI37489.1 - 7.6e-05 22.6 0.1 0.00013 21.8 0.1 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 KPI37489.1 - 0.0033 17.3 2.0 0.0059 16.5 2.0 1.4 1 0 0 1 1 1 1 F-box domain Aldo_ket_red PF00248.21 KPI37490.1 - 4.3e-69 232.9 0.0 5.4e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sigma_reg_N PF13800.6 KPI37491.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal GST_N_2 PF13409.6 KPI37494.1 - 5.7e-07 29.7 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI37494.1 - 2.4e-06 27.6 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI37494.1 - 8.2e-06 25.9 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI37494.1 - 2.9e-05 24.0 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI37494.1 - 3.7e-05 24.0 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI37494.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DIOX_N PF14226.6 KPI37496.1 - 2.1e-18 67.2 0.0 2.7e-17 63.6 0.0 2.5 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI37496.1 - 2.1e-06 28.1 0.0 4.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EthD PF07110.11 KPI37497.1 - 0.022 15.9 0.0 0.032 15.4 0.0 1.3 1 0 0 1 1 1 0 EthD domain TMEM247 PF15444.6 KPI37498.1 - 0.57 10.2 3.0 0.21 11.6 0.3 1.7 2 0 0 2 2 2 0 Transmembrane protein 247 PAP2 PF01569.21 KPI37499.1 - 2.4e-25 88.9 1.4 2.4e-25 88.9 1.4 2.0 2 1 0 2 2 2 1 PAP2 superfamily tRNA-synt_2_TM PF16995.5 KPI37499.1 - 0.011 15.4 3.5 0.29 10.8 0.0 3.0 3 0 0 3 3 3 0 Transmembrane region of lysyl-tRNA synthetase PAP2_3 PF14378.6 KPI37499.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.9 4 0 0 4 4 4 0 PAP2 superfamily CoA_transf_3 PF02515.17 KPI37500.1 - 7.6e-43 147.0 0.1 5.4e-41 140.9 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III PAP2_3 PF14378.6 KPI37501.1 - 7.9e-25 87.7 12.4 7.9e-25 87.7 12.4 2.2 3 0 0 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 KPI37501.1 - 6.2e-08 32.5 6.8 2.9e-07 30.3 6.8 2.1 1 0 0 1 1 1 1 PAP2 superfamily CbtB PF09489.10 KPI37501.1 - 0.27 11.4 0.1 0.27 11.4 0.1 3.2 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) SieB PF14163.6 KPI37501.1 - 0.64 9.5 3.3 2.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B Arrestin_N PF00339.29 KPI37502.1 - 7.4e-13 48.8 0.0 7.4e-09 35.8 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 KPI37502.1 - 0.007 15.8 0.0 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 Bul1 C terminus p450 PF00067.22 KPI37503.1 - 2.7e-53 181.4 0.0 3.5e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sirohm_synth_M PF14824.6 KPI37503.1 - 0.14 11.6 1.9 0.69 9.4 0.2 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central NCA2 PF08637.10 KPI37504.1 - 2e-107 358.7 0.3 4.7e-107 357.5 0.1 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 p450 PF00067.22 KPI37505.1 - 9.2e-54 182.9 0.0 1.1e-53 182.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KPI37506.1 - 4.3e-13 49.5 6.7 0.001 19.8 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI37506.1 - 1.4e-11 44.5 0.1 0.001 19.3 0.0 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI37506.1 - 5.5e-06 26.4 0.0 0.024 14.5 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KPI37506.1 - 0.0014 17.3 0.1 0.0025 16.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain BTB PF00651.31 KPI37507.1 - 5.8e-05 23.3 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 KPI37508.1 - 3.2e-06 27.2 8.4 5.4e-06 26.4 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 KPI37508.1 - 0.05 14.0 3.1 0.083 13.2 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RPA43_OB PF17875.1 KPI37510.1 - 1.9e-24 86.6 0.0 1.9e-24 86.6 0.0 3.3 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KPI37510.1 - 0.02 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Na_Ca_ex PF01699.24 KPI37511.1 - 7.3e-37 126.6 47.2 1.6e-19 70.4 19.4 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_31 PF01055.26 KPI37512.1 - 0.057 12.6 0.1 0.63 9.2 0.1 1.9 1 1 0 2 2 2 0 Glycosyl hydrolases family 31 FMN_red PF03358.15 KPI37513.1 - 1.6e-21 76.7 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Epimerase PF01370.21 KPI37514.1 - 6.1e-20 71.7 0.0 7.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI37514.1 - 5.2e-12 45.8 0.0 7.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI37514.1 - 1.1e-11 44.3 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KPI37514.1 - 1.9e-07 30.5 0.0 3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPI37514.1 - 2.8e-07 30.0 0.0 3.5e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.23 KPI37514.1 - 0.0033 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_64 PF16483.5 KPI37515.1 - 5.3e-127 424.1 0.1 6.2e-127 423.9 0.1 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Pyr_redox_2 PF07992.14 KPI37516.1 - 1e-52 179.2 0.2 1.5e-52 178.7 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KPI37516.1 - 9.2e-16 57.6 0.1 2.5e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KPI37516.1 - 3.9e-14 53.0 0.8 3.8e-12 46.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37516.1 - 1.3e-09 37.7 0.8 3.8e-05 23.1 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KPI37516.1 - 1.3e-06 28.3 0.0 3.7e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 KPI37516.1 - 1.9e-06 28.3 0.0 4.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 KPI37516.1 - 0.00087 18.5 0.0 0.29 10.2 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 KPI37516.1 - 0.0045 16.6 0.1 0.0079 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) HI0933_like PF03486.14 KPI37516.1 - 0.043 12.5 0.4 4.7 5.8 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 KPI37516.1 - 0.059 13.8 0.0 0.55 10.7 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KPI37516.1 - 0.18 11.8 0.0 37 4.3 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KPI37516.1 - 0.21 11.8 0.8 2.4 8.5 0.1 2.7 3 0 0 3 3 3 0 TrkA-N domain AMP-binding PF00501.28 KPI37517.1 - 1.9e-73 247.5 0.0 2.3e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI37517.1 - 1.8e-17 64.1 2.9 5.1e-17 62.6 2.9 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 KPI37518.1 - 1.7e-08 34.5 9.1 2.6e-08 33.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI37518.1 - 0.019 14.0 0.1 0.18 10.8 0.0 2.4 3 0 0 3 3 3 0 Fungal specific transcription factor domain SMRP1 PF15181.6 KPI37518.1 - 0.047 13.3 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 WD40 PF00400.32 KPI37519.1 - 1.7e-16 60.3 13.6 0.00033 21.4 0.1 6.1 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI37519.1 - 6e-16 58.5 5.7 1.6e-05 25.1 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI37519.1 - 4.5e-06 25.9 0.1 0.00033 19.7 0.0 3.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_16 PF00722.21 KPI37520.1 - 3e-44 150.6 2.9 5e-44 149.9 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KPI37520.1 - 0.049 14.1 13.2 0.12 12.8 13.2 1.6 1 0 0 1 1 1 0 Chitin recognition protein tRNA-synt_2d PF01409.20 KPI37523.1 - 3.8e-88 295.1 0.0 4.8e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KPI37523.1 - 4.5e-13 49.3 1.1 9e-13 48.3 0.1 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KPI37523.1 - 2.2e-07 30.5 0.0 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KPI37523.1 - 0.00012 21.3 0.1 0.0048 16.0 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) CLTH PF10607.9 KPI37524.1 - 1.8e-28 99.3 0.0 3.9e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KPI37524.1 - 7.5e-24 84.1 0.1 1.3e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KPI37524.1 - 0.0076 16.2 0.9 0.063 13.3 0.1 2.8 3 0 0 3 3 3 1 LisH Profilin PF00235.19 KPI37525.1 - 3.2e-53 179.3 0.6 3.6e-53 179.2 0.6 1.0 1 0 0 1 1 1 1 Profilin DUF4127 PF13552.6 KPI37525.1 - 0.089 11.4 0.0 0.096 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Forkhead PF00250.18 KPI37526.1 - 3.5e-17 62.5 0.0 6.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain RNA_pol_Rpb1_1 PF04997.12 KPI37528.1 - 1.1e-71 241.7 0.0 1.3e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Amidase PF01425.21 KPI37529.1 - 7.8e-66 222.9 0.0 1.1e-65 222.4 0.0 1.2 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 KPI37530.1 - 6.9e-22 78.2 0.1 9.1e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI37530.1 - 2.5e-07 30.2 1.6 3.6e-05 23.2 0.3 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI37530.1 - 1.2e-05 25.4 0.9 2.5e-05 24.4 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI37530.1 - 1.8e-05 24.5 6.4 0.042 13.4 3.4 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPI37530.1 - 3.6e-05 23.1 0.4 5.6e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KPI37530.1 - 0.0001 21.5 0.0 0.00042 19.5 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 KPI37530.1 - 0.0009 19.8 0.7 0.0032 18.0 0.4 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI37530.1 - 0.0015 17.7 0.9 0.0047 16.1 0.6 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI37530.1 - 0.0017 17.7 0.4 0.0052 16.1 0.4 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI37530.1 - 0.0017 17.5 3.1 0.0035 16.5 2.9 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI37530.1 - 0.0031 16.3 0.7 0.0055 15.5 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPI37530.1 - 0.0046 16.4 0.3 0.0078 15.6 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase STI1 PF17830.1 KPI37530.1 - 0.012 15.5 0.1 0.029 14.3 0.0 1.7 2 0 0 2 2 1 0 STI1 domain Trp_halogenase PF04820.14 KPI37530.1 - 0.023 13.6 0.7 0.2 10.4 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HDPD PF02924.14 KPI37530.1 - 0.13 12.3 5.9 2.1 8.4 5.9 2.2 1 1 0 1 1 1 0 Bacteriophage lambda head decoration protein D DUF3425 PF11905.8 KPI37531.1 - 1.5e-15 57.3 0.4 3.6e-15 56.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TSC22 PF01166.18 KPI37531.1 - 0.012 15.9 2.3 0.031 14.6 2.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Uds1 PF15456.6 KPI37531.1 - 0.77 9.9 6.8 1.4 9.1 6.8 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF4646 PF15496.6 KPI37532.1 - 0.0092 16.6 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 KPI37532.1 - 0.039 14.1 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family F_bP_aldolase PF01116.20 KPI37533.1 - 8.7e-81 271.5 0.1 9.9e-81 271.3 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II COesterase PF00135.28 KPI37534.1 - 1.9e-59 201.9 0.0 2.5e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI37534.1 - 1.2e-07 31.8 0.6 0.002 18.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold p450 PF00067.22 KPI37536.1 - 2.6e-43 148.4 0.0 3.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KPI37537.1 - 2e-23 82.8 0.0 2.3e-08 34.5 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KPI37537.1 - 6.2e-20 70.7 2.2 0.00021 21.6 0.2 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KPI37537.1 - 1.2e-16 60.8 0.2 2.6e-05 24.7 0.0 5.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI37537.1 - 3e-16 57.9 0.6 0.0024 18.2 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KPI37537.1 - 1.8e-13 50.4 1.0 0.0082 16.4 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) SesA PF17107.5 KPI37537.1 - 0.009 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases adh_short PF00106.25 KPI37539.1 - 3.8e-46 157.0 1.3 5.3e-46 156.5 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37539.1 - 1.8e-45 155.3 0.5 7.3e-45 153.3 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AA_kinase PF00696.28 KPI37539.1 - 3.8e-32 111.8 2.6 4.9e-32 111.4 0.4 1.9 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 KPI37539.1 - 9.7e-14 51.1 2.0 9.2e-13 48.0 0.4 2.9 2 1 0 2 2 2 1 PUA domain KR PF08659.10 KPI37539.1 - 1.4e-09 38.1 0.1 4.3e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KPI37539.1 - 0.00075 20.2 0.2 0.0021 18.7 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 KPI37539.1 - 0.029 14.3 0.4 0.073 13.0 0.4 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4396 PF14342.6 KPI37540.1 - 1.2e-35 123.0 12.0 1.2e-35 123.0 12.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4396) SelP_N PF04592.14 KPI37540.1 - 1.4 8.2 11.1 2 7.7 11.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAD_binding_3 PF01494.19 KPI37541.1 - 1.3e-28 100.2 3.5 5.1e-26 91.7 3.5 2.7 1 1 0 1 1 1 1 FAD binding domain Oxidored_molyb PF00174.19 KPI37542.1 - 1.2e-57 194.3 0.0 1.7e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KPI37542.1 - 1.6e-28 99.4 0.0 2.8e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KPI37542.1 - 1.8e-13 50.4 0.3 3e-12 46.5 0.1 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD-oxidase_C PF02913.19 KPI37543.1 - 1.1e-54 185.7 0.5 1.7e-54 185.1 0.5 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPI37543.1 - 2e-34 118.3 1.9 2.3e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Consortin_C PF15281.6 KPI37543.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus CAP_N PF01213.19 KPI37543.1 - 2.6 7.4 5.3 4.4 6.7 5.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EB1 PF03271.17 KPI37544.1 - 0.39 11.0 1.8 0.83 9.9 1.8 1.5 1 0 0 1 1 1 0 EB1-like C-terminal motif p450 PF00067.22 KPI37548.1 - 4.1e-53 180.8 0.0 7e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.6 KPI37548.1 - 1.2e-26 93.7 0.0 2.6e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI37548.1 - 1e-17 64.3 0.0 3e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI37548.1 - 2.4e-11 43.4 2.0 6.2e-08 32.2 0.2 3.2 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KPI37548.1 - 1.5e-10 41.5 0.4 0.02 15.5 0.0 3.6 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI37548.1 - 3.8e-10 38.8 0.1 1.2e-07 30.6 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like DAO PF01266.24 KPI37548.1 - 2.5e-07 30.6 6.7 0.0016 18.1 0.1 3.8 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI37548.1 - 9.7e-07 28.9 0.1 4.4e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI37548.1 - 2.7e-06 27.5 2.7 0.051 13.6 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KPI37548.1 - 4.1e-05 23.0 0.5 0.005 16.2 0.0 2.8 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KPI37548.1 - 6.6e-05 22.5 0.1 0.057 13.0 0.0 2.6 3 0 0 3 3 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 KPI37548.1 - 7.6e-05 21.6 1.5 0.23 10.1 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 KPI37548.1 - 0.00023 21.3 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KPI37548.1 - 0.0005 19.5 0.1 0.26 10.5 0.0 2.5 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KPI37548.1 - 0.00069 18.8 0.1 0.14 11.2 0.0 3.5 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPI37548.1 - 0.0013 18.0 0.1 0.0053 16.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KPI37548.1 - 0.0035 17.2 0.3 0.17 11.7 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPI37548.1 - 0.017 15.6 0.0 0.32 11.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KPI37548.1 - 0.053 12.8 0.0 1.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Thi4 family TrkA_N PF02254.18 KPI37548.1 - 0.099 12.9 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 KPI37548.1 - 0.12 13.0 0.1 2.6 8.7 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 KPI37548.1 - 3.4 6.7 6.6 1.7 7.7 1.3 2.7 2 1 1 3 3 3 0 FAD binding domain DUF2839 PF10999.8 KPI37549.1 - 0.0042 17.4 0.1 0.029 14.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2839) CAP PF00188.26 KPI37550.1 - 0.001 19.9 0.1 0.0021 18.9 0.1 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sulfate_transp PF00916.20 KPI37551.1 - 5e-86 288.8 15.7 6.2e-86 288.5 15.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPI37551.1 - 5.2e-13 48.7 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.6 KPI37551.1 - 0.025 14.2 1.5 0.071 12.7 1.5 1.7 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF1516 PF07457.11 KPI37551.1 - 1.6 9.0 6.2 2.8 8.2 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1516) Cast PF10174.9 KPI37552.1 - 0.00056 18.3 2.5 0.00079 17.8 2.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone NUDE_C PF04880.13 KPI37552.1 - 0.0011 19.5 1.6 0.0011 19.5 1.6 2.6 1 1 0 2 2 1 1 NUDE protein, C-terminal conserved region FAM184 PF15665.5 KPI37552.1 - 0.024 14.4 5.1 0.041 13.7 5.1 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF3450 PF11932.8 KPI37552.1 - 0.036 13.4 1.8 0.22 10.8 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 KPI37552.1 - 0.04 13.6 0.3 0.081 12.6 0.2 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF1631 PF07793.11 KPI37552.1 - 0.061 11.7 10.8 0.089 11.2 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MPS2 PF17060.5 KPI37552.1 - 0.086 12.1 2.6 0.11 11.8 0.3 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 Fanconi_A PF03511.14 KPI37552.1 - 0.09 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Cnn_1N PF07989.11 KPI37552.1 - 0.25 11.5 2.4 0.5 10.6 2.4 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 CCDC92 PF14916.6 KPI37552.1 - 0.31 10.8 6.8 0.046 13.5 2.7 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function PRCC PF10253.9 KPI37552.1 - 0.75 10.5 9.8 2 9.2 6.5 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting SNF2_N PF00176.23 KPI37553.1 - 5.7e-51 173.3 0.3 8.7e-51 172.7 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI37553.1 - 1.7e-17 63.7 0.0 1.6e-16 60.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 KPI37553.1 - 1.9e-15 56.7 0.2 1.9e-15 56.7 0.2 2.6 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal ERCC3_RAD25_C PF16203.5 KPI37553.1 - 2.6e-07 30.1 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KPI37553.1 - 3.2e-07 30.5 0.3 1.8e-06 28.1 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2188 PF09954.9 KPI37553.1 - 1.8 8.7 5.1 1.2 9.3 0.3 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF1774 PF08611.10 KPI37554.1 - 1.5e-23 82.9 10.6 1.5e-23 82.9 10.6 2.5 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) DnaJ PF00226.31 KPI37555.1 - 2.2e-13 50.1 0.0 4.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Zn_clus PF00172.18 KPI37555.1 - 1.4e-09 37.9 7.7 2.5e-09 37.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1720 PF08226.11 KPI37556.1 - 0.16 12.4 4.9 2.7 8.5 4.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) DUF3682 PF12446.8 KPI37556.1 - 1.6 9.2 7.8 2 8.9 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) WD40 PF00400.32 KPI37557.1 - 2.7e-17 62.8 1.5 0.0026 18.6 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI37557.1 - 4.7e-09 36.4 0.0 0.00062 20.0 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI37557.1 - 0.0028 17.6 0.1 5.5 6.8 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPI37557.1 - 0.0048 15.9 0.3 0.4 9.6 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPI37557.1 - 0.0074 15.0 0.0 0.11 11.1 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PilX PF13681.6 KPI37557.1 - 0.059 13.7 0.1 0.17 12.3 0.0 1.9 2 1 0 2 2 2 0 Type IV pilus assembly protein PilX C-term RINT1_TIP1 PF04437.13 KPI37559.1 - 1.7e-151 505.5 0.2 5.6e-151 503.8 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Caldesmon PF02029.15 KPI37559.1 - 0.021 13.6 3.9 0.04 12.7 3.9 1.4 1 0 0 1 1 1 0 Caldesmon DIL PF01843.19 KPI37559.1 - 0.051 13.8 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 DIL domain Plasmid_RAQPRD PF09686.10 KPI37559.1 - 0.12 12.6 7.6 0.66 10.2 7.2 2.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF4404 PF14357.6 KPI37559.1 - 0.35 11.5 8.0 0.93 10.2 5.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Nup54 PF13874.6 KPI37559.1 - 0.44 10.7 16.7 0.32 11.1 13.5 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 FemAB PF02388.16 KPI37559.1 - 0.8 8.5 5.1 1.5 7.7 5.1 1.3 1 0 0 1 1 1 0 FemAB family Snapin_Pallidin PF14712.6 KPI37559.1 - 6.4 7.3 12.6 32 5.0 9.4 3.1 1 1 0 2 2 2 0 Snapin/Pallidin Lipase_3 PF01764.25 KPI37560.1 - 2.7e-05 24.0 0.0 5.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KPI37560.1 - 0.00049 20.8 0.1 0.0013 19.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KPI37560.1 - 0.023 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KPI37560.1 - 0.18 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 6PGD PF00393.19 KPI37561.1 - 1.3e-87 293.9 0.0 1.6e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KPI37561.1 - 1.1e-26 93.9 0.0 2.2e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI37561.1 - 0.083 13.1 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF3399 PF11879.8 KPI37561.1 - 0.15 12.4 0.2 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) 3HCDH_N PF02737.18 KPI37561.1 - 0.21 11.5 0.0 0.9 9.4 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PROCN PF08083.11 KPI37562.1 - 2.2e-222 738.1 9.0 2.2e-222 738.1 9.0 2.2 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KPI37562.1 - 3.5e-124 412.9 2.1 6.2e-124 412.1 2.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KPI37562.1 - 1.9e-89 297.7 1.9 6.8e-89 295.9 1.9 2.1 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KPI37562.1 - 8.8e-81 269.2 3.1 2.9e-80 267.6 3.1 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KPI37562.1 - 2.7e-70 234.7 0.1 7e-70 233.3 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KPI37562.1 - 6.4e-48 161.0 0.3 2e-47 159.4 0.3 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KPI37562.1 - 1.5e-41 141.2 0.1 5.4e-41 139.4 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF5074 PF16819.5 KPI37563.1 - 0.011 15.8 0.6 0.015 15.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) zf-C2H2 PF00096.26 KPI37564.1 - 0.0059 17.0 18.9 6.7 7.4 0.3 6.3 6 1 0 6 6 6 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI37564.1 - 0.02 15.7 29.1 6.5 7.9 0.2 6.7 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI37564.1 - 0.026 14.8 0.3 0.026 14.8 0.3 6.0 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Vps36-NZF-N PF16988.5 KPI37564.1 - 0.038 13.4 0.1 0.94 8.9 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-CHC2 PF01807.20 KPI37564.1 - 0.048 13.5 1.5 6.8 6.6 0.1 2.6 2 0 0 2 2 2 0 CHC2 zinc finger A2L_zn_ribbon PF08792.10 KPI37564.1 - 0.05 13.3 6.3 2.4 8.0 0.0 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain C1_2 PF03107.16 KPI37564.1 - 0.17 12.2 0.4 0.17 12.2 0.4 5.4 4 2 1 5 5 5 0 C1 domain TF_Zn_Ribbon PF08271.12 KPI37564.1 - 1.5 8.4 8.9 18 5.0 0.1 4.2 4 0 0 4 4 4 0 TFIIB zinc-binding CTU2 PF10288.9 KPI37564.1 - 1.6 9.0 8.7 11 6.3 5.2 3.1 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_3rep PF18868.1 KPI37564.1 - 5.4 7.7 12.4 2 9.1 3.4 3.6 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF3482 PF11981.8 KPI37565.1 - 0.039 13.3 0.5 0.07 12.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CRCB PF02537.15 KPI37566.1 - 3.4e-29 101.0 6.5 9.9e-22 77.1 3.4 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) VHS PF00790.19 KPI37566.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF1275 PF06912.11 KPI37567.1 - 5e-45 153.8 8.3 6.1e-45 153.5 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KPI37567.1 - 5.4e-05 22.3 8.5 0.00015 20.9 0.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.9 KPI37567.1 - 0.0067 17.1 0.0 0.036 14.7 0.0 2.2 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Peptidase_S10 PF00450.22 KPI37568.1 - 6.8e-92 309.1 0.7 2.9e-59 201.5 0.4 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase DUF5305 PF17231.2 KPI37569.1 - 0.13 11.7 3.2 0.28 10.6 3.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF1541 PF07563.11 KPI37569.1 - 0.18 11.7 2.8 0.36 10.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) CDT1_C PF16679.5 KPI37570.1 - 1.5e-13 51.0 1.0 1.2e-12 48.1 0.0 2.8 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain Fungal_lectin PF07938.12 KPI37571.1 - 1.1e-06 28.3 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Fungal fucose-specific lectin Arf PF00025.21 KPI37572.1 - 7.8e-38 129.7 0.0 8.4e-17 61.2 0.0 3.1 3 0 0 3 3 3 3 ADP-ribosylation factor family G-alpha PF00503.20 KPI37572.1 - 1.7e-10 40.6 0.0 0.0011 18.2 0.0 2.9 3 0 0 3 3 3 2 G-protein alpha subunit Roc PF08477.13 KPI37572.1 - 2e-07 31.2 0.0 0.00026 21.2 0.0 2.5 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KPI37572.1 - 4.7e-05 23.0 0.0 0.15 11.7 0.0 3.1 3 0 0 3 3 3 2 Ras family MMR_HSR1 PF01926.23 KPI37572.1 - 6.6e-05 23.0 0.0 0.00021 21.4 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KPI37572.1 - 0.00023 20.7 0.1 0.065 12.7 0.1 2.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KPI37572.1 - 0.00064 19.3 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI37572.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KPI37572.1 - 0.066 12.7 0.1 0.57 9.7 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Aminotran_5 PF00266.19 KPI37573.1 - 1.3e-50 172.5 0.0 1.8e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 KPI37573.1 - 3.1e-23 82.3 51.5 1.3e-16 60.5 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cys_Met_Meta_PP PF01053.20 KPI37573.1 - 0.00031 19.4 0.0 0.0005 18.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPI37573.1 - 0.0013 18.0 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ScsC_N PF18312.1 KPI37573.1 - 0.22 11.3 0.1 0.42 10.5 0.1 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Kelch_6 PF13964.6 KPI37574.1 - 1.2e-24 85.7 1.7 1.1e-05 25.6 0.0 4.6 2 1 2 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KPI37574.1 - 7.9e-24 83.4 4.5 3.3e-06 27.0 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KPI37574.1 - 1.3e-23 82.5 0.9 8.4e-06 25.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KPI37574.1 - 4.4e-21 74.0 1.1 5.6e-07 29.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KPI37574.1 - 7e-21 74.0 8.9 1.2e-08 35.0 0.1 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KPI37574.1 - 5.7e-19 67.4 1.7 2.4e-05 23.8 0.1 4.5 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 KPI37574.1 - 4.9e-10 39.6 0.1 9.5e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KPI37574.1 - 0.025 14.7 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch 2-Hacid_dh_C PF02826.19 KPI37575.1 - 1.1e-52 178.0 0.0 1.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI37575.1 - 5.1e-20 71.5 0.0 5.7e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KPI37575.1 - 1.2e-09 38.4 0.0 1.3e-05 25.3 0.1 2.3 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KPI37575.1 - 0.00034 20.8 0.1 0.00062 20.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPI37575.1 - 0.0011 19.5 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Phage_fiber_2 PF03406.13 KPI37575.1 - 0.096 12.3 2.4 0.17 11.5 2.4 1.4 1 0 0 1 1 1 0 Phage tail fibre repeat DUF4164 PF13747.6 KPI37576.1 - 0.11 12.8 11.7 2 8.8 6.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Taxilin PF09728.9 KPI37576.1 - 0.37 9.9 8.0 0.12 11.5 3.4 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein PI3K_P85_iSH2 PF16454.5 KPI37576.1 - 1.1 8.8 8.8 0.85 9.2 4.9 2.5 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 KPI37576.1 - 1.3 7.9 11.7 0.83 8.5 6.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KPI37576.1 - 1.5 8.1 5.8 6.4 6.0 5.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KPI37576.1 - 2.1 9.0 6.7 60 4.3 3.6 3.1 1 1 1 3 3 3 0 Initiation control protein YabA DUF4140 PF13600.6 KPI37576.1 - 2.2 8.8 5.5 4.1 7.9 0.6 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 KPI37576.1 - 3.4 8.3 13.4 10 6.8 0.6 3.5 2 1 1 3 3 3 0 SlyX YlqD PF11068.8 KPI37576.1 - 3.5 8.0 11.1 0.72 10.2 7.0 1.9 2 0 0 2 2 2 0 YlqD protein Fib_alpha PF08702.10 KPI37576.1 - 3.8 7.7 8.4 2.3 8.4 2.5 2.8 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Uds1 PF15456.6 KPI37576.1 - 4.3 7.5 8.4 4 7.6 0.5 2.6 1 1 2 3 3 3 0 Up-regulated During Septation Fez1 PF06818.15 KPI37576.1 - 5.8 7.3 11.7 1.4 9.3 4.7 2.4 1 1 0 2 2 2 0 Fez1 CENP-H PF05837.12 KPI37576.1 - 8.1 6.9 10.1 1.7 9.1 4.4 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 KPI37576.1 - 9 6.5 17.7 0.53 10.4 3.5 4.2 3 1 2 5 5 5 0 TolA binding protein trimerisation IQCJ-SCHIP1 PF15157.6 KPI37577.1 - 0.0095 15.8 0.2 0.017 15.0 0.2 1.4 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif Cupin_1 PF00190.22 KPI37578.1 - 1.6e-16 60.3 0.8 2.5e-16 59.6 0.8 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPI37578.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AbiEi_2 PF09952.9 KPI37578.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system HATPase_c PF02518.26 KPI37579.1 - 3.1e-23 82.4 0.0 7.3e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 KPI37579.1 - 5.1e-13 49.0 0.0 2.1e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KPI37579.1 - 2.3e-10 40.6 0.1 5.2e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 KPI37579.1 - 7.2e-10 38.8 0.5 1.9e-09 37.4 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KPI37579.1 - 3.4e-09 36.8 4.6 2.9e-08 33.8 2.4 3.0 2 1 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 KPI37579.1 - 1.9e-08 34.5 0.0 1.8e-06 28.1 0.0 3.6 4 0 0 4 4 4 1 PAS fold PAS_9 PF13426.7 KPI37579.1 - 1.9e-07 31.3 0.0 2.3e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.6 KPI37579.1 - 2.7e-05 24.5 0.0 0.0015 18.8 0.0 3.3 3 0 0 3 3 3 1 GAF domain PAS_8 PF13188.7 KPI37579.1 - 0.00014 21.8 0.2 0.0029 17.6 0.1 2.9 2 0 0 2 2 2 1 PAS domain GAF PF01590.26 KPI37579.1 - 0.0027 18.3 0.0 0.031 14.9 0.0 2.8 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.6 KPI37579.1 - 0.012 15.9 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 GAF domain GA PF01468.17 KPI37579.1 - 0.061 13.6 0.6 0.16 12.3 0.6 1.6 1 0 0 1 1 1 0 GA module Piwi PF02171.17 KPI37580.1 - 7.4e-55 186.3 0.0 1e-54 185.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KPI37580.1 - 8e-07 29.8 0.0 2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KPI37580.1 - 0.01 15.5 0.0 0.033 13.8 0.0 2.0 1 0 0 1 1 1 0 Argonaute linker 1 domain ArgoMid PF16487.5 KPI37580.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Mid domain of argonaute Ribosomal_L34e PF01199.18 KPI37581.1 - 5.3e-26 90.8 11.1 4e-16 59.1 0.3 2.4 2 1 1 3 3 3 2 Ribosomal protein L34e Zn_clus PF00172.18 KPI37583.1 - 6.7e-05 22.9 9.9 0.00012 22.1 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI37583.1 - 0.00044 19.4 0.0 0.00079 18.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Erythro-docking PF09277.11 KPI37583.1 - 0.019 14.9 0.2 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking Cupin_1 PF00190.22 KPI37584.1 - 1.4e-42 144.8 0.0 8.6e-21 74.1 0.1 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPI37584.1 - 6.9e-27 93.0 0.6 1.6e-12 46.9 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPI37584.1 - 2.5e-09 36.7 0.0 0.0016 18.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPI37584.1 - 2e-07 31.0 0.2 0.0027 17.6 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KPI37584.1 - 0.00026 20.9 0.0 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 KPI37584.1 - 0.0015 18.7 0.2 0.056 13.6 0.0 2.3 2 0 0 2 2 2 1 ARD/ARD' family SRC-1 PF08832.10 KPI37584.1 - 0.0043 18.1 0.2 1.5 9.9 0.0 2.5 2 0 0 2 2 2 1 Steroid receptor coactivator FAS_I_H PF18314.1 KPI37585.1 - 1.4e-79 266.5 0.1 3.5e-79 265.2 0.1 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KPI37585.1 - 2.9e-69 232.6 0.0 7.7e-69 231.2 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KPI37585.1 - 2.1e-20 73.4 0.0 4.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KPI37585.1 - 8.4e-20 71.0 0.0 1.9e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KPI37585.1 - 7.6e-11 42.1 0.0 1.9e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KPI37585.1 - 5.9e-06 25.9 0.0 2.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI37585.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 KR domain PnpCD_PnpD_N PF18191.1 KPI37585.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal 4PPT_N PF17837.1 KPI37585.1 - 0.28 11.3 0.7 2.4 8.4 0.7 2.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain TMEM208_SND2 PF05620.11 KPI37586.1 - 0.05 13.4 0.1 0.13 12.0 0.1 1.6 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF1479 PF07350.12 KPI37587.1 - 7.7e-09 34.8 0.0 0.00045 19.1 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.13 KPI37587.1 - 2.3e-08 34.5 0.0 4.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 KPI37589.1 - 5.2e-09 36.1 5.7 1.4e-08 34.7 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI37589.1 - 9.9e-08 31.3 0.5 1.6e-07 30.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain XLF PF09302.11 KPI37590.1 - 6.3e-16 59.1 3.3 6.5e-16 59.0 0.1 2.4 2 1 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component MMM1 PF10296.9 KPI37591.1 - 5e-08 32.4 0.0 2e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Cadherin_tail PF15974.5 KPI37592.1 - 9.7 6.5 11.9 0.29 11.5 5.0 2.0 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Yae1_N PF09811.9 KPI37593.1 - 1.6e-08 34.1 3.0 2.9e-08 33.3 3.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MFS_1 PF07690.16 KPI37594.1 - 1.6e-28 99.7 27.0 2e-28 99.3 27.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_C14 PF00656.22 KPI37595.1 - 5.8e-12 46.1 0.0 7.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF2063 PF09836.9 KPI37596.1 - 0.082 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative DNA-binding domain DNA_ligase_A_M PF01068.21 KPI37597.1 - 1.5e-50 171.7 0.6 7.2e-48 162.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPI37597.1 - 2.3e-33 115.9 0.0 4.2e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KPI37597.1 - 2.5e-19 69.7 0.0 1.5e-18 67.2 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KPI37597.1 - 0.032 14.1 0.1 2 8.2 0.0 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Sugar_tr PF00083.24 KPI37598.1 - 2.4e-81 273.9 23.2 2.7e-81 273.7 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37598.1 - 1.1e-24 87.1 23.7 2.3e-23 82.7 21.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TPR_16 PF13432.6 KPI37598.1 - 0.035 14.8 0.4 0.09 13.4 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GST_N PF02798.20 KPI37600.1 - 2.9e-15 56.4 0.3 1.8e-14 53.8 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI37600.1 - 2.9e-14 53.2 0.0 5.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI37600.1 - 2e-12 47.1 0.1 4.2e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI37600.1 - 5.5e-11 42.6 0.0 9.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI37600.1 - 1.5e-09 37.9 0.1 2.9e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KPI37600.1 - 0.00085 19.6 0.3 0.054 13.8 0.0 2.1 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KPI37600.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KPI37600.1 - 0.18 11.6 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alk_phosphatase PF00245.20 KPI37602.1 - 6.2e-104 348.2 1.8 1.9e-103 346.6 1.8 2.3 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KPI37602.1 - 5.9e-05 22.6 0.1 9.9e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Histidinol_dh PF00815.20 KPI37603.1 - 1.3e-160 534.9 3.1 1.8e-160 534.4 2.6 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 KPI37603.1 - 9.6e-24 83.0 0.4 1.8e-23 82.1 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KPI37603.1 - 1.9e-14 53.9 0.6 1e-13 51.5 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KPI37603.1 - 0.011 15.9 0.3 0.024 14.8 0.3 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Lactamase_B_3 PF13483.6 KPI37604.1 - 6.1e-07 29.5 0.1 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KPI37604.1 - 8.4e-05 22.2 0.1 0.00019 21.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cnn_1N PF07989.11 KPI37606.1 - 0.014 15.5 1.0 0.014 15.5 1.0 1.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1729 PF08354.10 KPI37607.1 - 1.4e-160 534.0 0.0 2.3e-160 533.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KPI37607.1 - 8.9e-93 311.3 0.1 2.6e-89 299.9 0.0 2.9 3 0 0 3 3 3 2 Acyl transferase domain FAS_meander PF17951.1 KPI37607.1 - 4.9e-54 182.1 0.0 1.4e-53 180.6 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KPI37607.1 - 3.3e-40 138.3 0.1 1.3e-39 136.4 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KPI37607.1 - 4.7e-38 129.5 0.0 1.2e-37 128.2 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KPI37607.1 - 5.3e-37 126.7 0.0 1.5e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KPI37607.1 - 1.1e-22 80.6 0.0 6.1e-22 78.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MCRS_N PF13325.6 KPI37607.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein TRP PF06011.12 KPI37608.1 - 1.9e-37 129.0 20.2 7e-36 123.9 20.2 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPI37608.1 - 6.1e-19 68.8 0.0 9.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 ML-like domain PAC4 PF16093.5 KPI37608.1 - 0.14 12.3 1.6 1.1 9.5 1.6 2.4 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 Pyr_redox_3 PF13738.6 KPI37609.1 - 2.8e-11 43.2 0.0 1.6e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI37609.1 - 1e-09 38.1 0.0 3.7e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPI37609.1 - 9.7e-09 34.2 0.0 2.1e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI37609.1 - 0.0016 17.8 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Neuregulin PF02158.15 KPI37609.1 - 0.0049 16.3 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region adh_short PF00106.25 KPI37610.1 - 4.9e-31 107.7 0.0 3e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37610.1 - 8.3e-23 81.2 0.0 6.3e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37610.1 - 1.9e-06 27.9 0.6 0.013 15.4 0.5 3.0 2 1 0 2 2 2 2 KR domain VSP PF03302.13 KPI37613.1 - 0.012 14.6 0.2 0.015 14.2 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4267 PF14087.6 KPI37614.1 - 8.5e-23 80.6 2.2 1.1e-22 80.3 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4149 PF13664.6 KPI37614.1 - 0.024 14.9 0.1 0.087 13.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) RSN1_7TM PF02714.15 KPI37615.1 - 2.4e-89 299.3 16.3 3.7e-89 298.7 16.3 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KPI37615.1 - 9.6e-24 84.6 0.0 1.6e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPI37615.1 - 1.3e-20 73.4 0.1 3e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 KPI37615.1 - 2.1e-14 53.6 0.1 1.3e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4446 PF14584.6 KPI37615.1 - 0.03 14.3 0.0 18 5.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) ABC_tran_CTD PF16326.5 KPI37615.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain ZapB PF06005.12 KPI37615.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.5 3 0 0 3 3 3 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 KPI37615.1 - 0.3 11.1 0.0 0.3 11.1 0.0 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Cytomega_TRL10 PF06084.11 KPI37615.1 - 3.7 7.5 4.2 7.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein adh_short_C2 PF13561.6 KPI37616.1 - 5.1e-42 144.0 0.0 6.7e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI37616.1 - 1.9e-28 99.2 0.0 2.5e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI37616.1 - 1.3e-08 34.9 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37616.1 - 0.037 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI37616.1 - 0.057 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AA_permease PF00324.21 KPI37617.1 - 3.8e-110 368.7 41.4 4.3e-110 368.6 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI37617.1 - 4.4e-28 98.3 48.5 5.4e-28 98.0 48.5 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S21e PF01249.18 KPI37618.1 - 4e-42 142.2 0.1 4.4e-42 142.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_1g PF09334.11 KPI37619.1 - 2e-150 500.9 0.0 2.9e-150 500.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KPI37619.1 - 2.8e-08 32.5 0.9 1.8e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.7 KPI37619.1 - 0.12 12.4 2.3 0.31 11.1 2.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KPI37619.1 - 2.2 7.8 6.9 7.3 6.2 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain AA_permease_2 PF13520.6 KPI37620.1 - 4.4e-79 266.3 27.1 5.2e-79 266.1 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI37620.1 - 3.9e-22 78.5 23.2 4.8e-22 78.2 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KPI37620.1 - 0.00013 20.9 10.8 0.00031 19.6 10.8 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 KPI37620.1 - 0.057 12.2 0.0 0.057 12.2 0.0 2.3 3 0 0 3 3 3 0 Spore germination protein DUF1600 PF07667.11 KPI37620.1 - 0.26 11.5 6.9 0.064 13.4 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) DUF2347 PF09804.9 KPI37621.1 - 9.6e-92 307.6 0.0 1.3e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KPI37621.1 - 1.3e-42 146.3 10.3 7.3e-32 111.1 1.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) SPA PF08616.10 KPI37621.1 - 5.3e-05 23.1 0.0 8.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KPI37621.1 - 0.00014 20.7 0.1 0.12 11.1 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 Chal_sti_synt_N PF00195.19 KPI37622.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain RNA_pol_Rpb1_5 PF04998.17 KPI37623.1 - 2e-98 329.1 0.0 2.9e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KPI37623.1 - 2.3e-75 252.4 0.0 4.2e-75 251.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KPI37623.1 - 2.3e-56 190.6 0.2 4e-56 189.9 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KPI37623.1 - 5.8e-46 156.3 0.0 1.1e-45 155.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KPI37623.1 - 2.3e-40 137.7 2.4 4e-40 136.9 2.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KPI37623.1 - 2.4e-32 111.1 0.7 5.6e-32 109.9 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KPI37623.1 - 3.7e-15 55.4 228.9 0.0043 17.3 8.7 15.0 11 1 4 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_1 PF04997.12 KPI37623.1 - 1.1e-10 41.4 0.8 2.1e-10 40.5 0.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Kinesin PF00225.23 KPI37624.1 - 5e-115 384.0 0.0 7.1e-115 383.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPI37624.1 - 3.2e-25 88.8 0.1 8.7e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KPI37624.1 - 0.021 15.0 0.0 0.083 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPI37624.1 - 0.034 13.9 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Herpes_UL14 PF03580.14 KPI37624.1 - 2.8 8.2 8.5 0.38 11.0 2.7 2.2 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Enolase_C PF00113.22 KPI37625.1 - 1.6e-111 372.3 0.0 2.2e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KPI37625.1 - 9.7e-48 161.6 0.1 1.5e-47 161.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KPI37625.1 - 4.1e-06 26.5 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Pkinase PF00069.25 KPI37627.1 - 8.9e-72 241.6 0.0 2.6e-71 240.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37627.1 - 9.1e-49 166.1 0.0 1.6e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI37627.1 - 0.00092 18.1 0.0 0.0025 16.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KPI37627.1 - 0.068 12.5 0.0 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like K_channel_TID PF07941.11 KPI37627.1 - 0.45 11.0 13.6 0.13 12.8 9.7 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain UNC45-central PF11701.8 KPI37627.1 - 1.2 9.0 3.8 6.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF3070 PF11270.8 KPI37628.1 - 0.089 13.0 0.0 0.86 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) FYVE PF01363.21 KPI37629.1 - 3.6e-20 71.9 5.5 3.6e-20 71.9 5.5 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KPI37629.1 - 7.7e-08 32.6 5.1 7.7e-08 32.6 5.1 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI37629.1 - 8.2e-05 22.4 3.9 8.2e-05 22.4 3.9 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI37629.1 - 0.00016 21.3 5.3 0.00016 21.3 5.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KPI37629.1 - 0.0011 19.2 6.6 0.0011 19.2 6.6 3.0 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI37629.1 - 0.0049 16.9 2.9 0.021 14.9 1.6 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KPI37629.1 - 0.012 15.5 4.0 0.012 15.5 4.0 4.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KPI37629.1 - 0.017 15.2 4.7 0.034 14.3 2.6 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain FYVE_2 PF02318.16 KPI37629.1 - 9.4 6.5 9.4 0.18 12.0 2.2 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Membr_traf_MHD PF10540.9 KPI37630.1 - 2.2e-22 79.8 0.6 4.6e-10 39.9 0.1 3.2 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KPI37630.1 - 6.5e-15 55.3 0.0 1.6e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KPI37630.1 - 2.4e-06 26.4 3.0 2.5e-06 26.3 1.0 1.9 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) TipAS PF07739.13 KPI37630.1 - 0.056 14.0 1.6 6.5 7.3 0.0 4.1 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain K_channel_TID PF07941.11 KPI37630.1 - 1.5 9.3 10.4 0.62 10.6 1.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Oxidored_FMN PF00724.20 KPI37632.1 - 6.7e-50 170.3 0.0 5.7e-31 108.0 0.0 3.0 2 1 1 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Ferric_reduct PF01794.19 KPI37633.1 - 2.6e-24 85.7 7.2 7.2e-24 84.3 7.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPI37633.1 - 2.4e-18 66.7 0.0 5.3e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI37633.1 - 1.6e-11 44.3 0.0 3.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPI37633.1 - 0.0019 18.8 0.0 0.0048 17.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TMEM187 PF15100.6 KPI37633.1 - 0.0065 16.1 1.6 0.012 15.2 1.6 1.3 1 0 0 1 1 1 1 TMEM187 protein family DUF4808 PF16066.5 KPI37633.1 - 0.041 14.4 1.0 0.15 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) MFS_1 PF07690.16 KPI37634.1 - 5.3e-10 38.8 26.8 5.3e-10 38.8 26.8 2.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Pro_dh PF01619.18 KPI37635.1 - 3e-64 217.4 0.6 3.5e-64 217.2 0.6 1.0 1 0 0 1 1 1 1 Proline dehydrogenase Atx10homo_assoc PF09759.9 KPI37635.1 - 0.053 13.6 0.9 0.45 10.6 0.1 2.3 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain INO80_Ies4 PF08193.11 KPI37636.1 - 9.7e-57 192.7 18.6 9.7e-57 192.7 18.6 1.7 1 1 1 2 2 2 1 INO80 complex subunit Ies4 BNIP2 PF12496.8 KPI37638.1 - 0.0034 17.8 1.5 0.0041 17.6 0.3 1.7 1 1 1 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RAP1 PF07218.11 KPI37638.1 - 0.0063 14.9 0.3 0.0076 14.6 0.3 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) FAM76 PF16046.5 KPI37638.1 - 0.007 15.8 1.0 0.0089 15.4 1.0 1.1 1 0 0 1 1 1 1 FAM76 protein FTA4 PF13093.6 KPI37638.1 - 0.031 14.2 0.8 0.037 13.9 0.8 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3347 PF11827.8 KPI37638.1 - 0.059 13.6 2.8 0.085 13.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Occludin_ELL PF07303.13 KPI37638.1 - 0.069 13.9 0.2 0.13 13.0 0.2 1.6 1 0 0 1 1 1 0 Occludin homology domain FAD-SLDH PF12318.8 KPI37638.1 - 0.077 13.1 0.9 0.13 12.3 0.9 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase COG2 PF06148.11 KPI37638.1 - 0.11 12.6 0.7 0.23 11.5 0.2 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PRD_Mga PF08270.11 KPI37638.1 - 0.13 11.9 0.3 0.19 11.4 0.3 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Mei5 PF10376.9 KPI37638.1 - 0.86 9.4 4.7 1.2 8.9 0.7 2.3 1 1 1 2 2 2 0 Double-strand recombination repair protein SNF2_N PF00176.23 KPI37639.1 - 2.1e-59 201.0 0.0 4.2e-59 200.0 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI37639.1 - 2.3e-17 63.4 0.0 4.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI37639.1 - 5e-10 39.6 0.0 8.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KPI37639.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA PF00004.29 KPI37640.1 - 2.4e-12 47.4 0.0 5.3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI37640.1 - 4.4e-06 27.0 0.0 1.7e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KPI37640.1 - 2.5e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KPI37640.1 - 5e-05 23.3 0.3 0.00022 21.2 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KPI37640.1 - 9.7e-05 22.2 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI37640.1 - 0.00053 20.4 0.4 0.0036 17.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KPI37640.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPI37640.1 - 0.0017 18.5 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KPI37640.1 - 0.0024 17.5 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KPI37640.1 - 0.0059 15.9 0.5 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KPI37640.1 - 0.01 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KPI37640.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KPI37640.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KPI37640.1 - 0.021 15.2 0.1 0.14 12.4 0.1 2.3 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KPI37640.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KPI37640.1 - 0.049 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI37640.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KPI37640.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KPI37640.1 - 0.1 11.8 0.2 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain FMO-like PF00743.19 KPI37641.1 - 9.3e-14 50.7 0.0 1.5e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI37641.1 - 3e-07 30.6 0.0 8.9e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI37641.1 - 1.2e-06 28.0 0.1 2.5e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI37641.1 - 2e-06 27.3 0.0 1.9e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI37641.1 - 3.5e-05 23.2 0.0 0.0057 15.9 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI37641.1 - 0.0072 16.0 0.1 0.065 12.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI37641.1 - 0.087 12.8 0.3 0.54 10.2 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding AP_endonuc_2 PF01261.24 KPI37642.1 - 1.2e-30 106.5 0.0 4.6e-30 104.6 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel SLAC1 PF03595.17 KPI37643.1 - 9.9e-83 278.1 52.7 1.2e-82 277.8 52.7 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1003 PF06210.11 KPI37643.1 - 0.54 10.4 0.0 0.54 10.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1003) PMSR PF01625.21 KPI37645.1 - 4.5e-59 199.0 0.5 5.4e-59 198.8 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LysM PF01476.20 KPI37646.1 - 2.7e-06 27.3 0.1 7.6e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 LysM domain Mucin PF01456.17 KPI37646.1 - 0.16 12.0 17.2 0.4 10.7 17.2 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein NAD_binding_2 PF03446.15 KPI37647.1 - 1.7e-24 86.8 0.0 1.2e-22 80.8 0.0 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI37647.1 - 1.5e-23 83.4 0.0 2.2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KPI37647.1 - 0.0046 17.5 0.0 0.0099 16.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KPI37647.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Abhydrolase_6 PF12697.7 KPI37648.1 - 1.1e-13 52.4 1.0 1.4e-13 52.0 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNase_PH PF01138.21 KPI37649.1 - 1e-36 126.4 1.0 3.7e-36 124.5 0.3 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RTA1 PF04479.13 KPI37650.1 - 2.1e-67 226.8 8.6 3.3e-67 226.1 8.6 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.16 KPI37651.1 - 8.2e-38 130.2 30.5 8.2e-38 130.2 30.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI37651.1 - 0.00044 19.7 8.4 0.0042 16.4 0.4 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Orf78 PF06024.12 KPI37651.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Glyco_hydro_72 PF03198.14 KPI37653.1 - 1.8e-68 231.1 0.0 2.4e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_75 PF07335.11 KPI37653.1 - 0.011 16.0 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 Cellulase PF00150.18 KPI37653.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Arrestin_N PF00339.29 KPI37654.1 - 4.2e-10 39.9 0.0 8.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ctr PF04145.15 KPI37655.1 - 2e-40 138.8 0.3 2.4e-40 138.6 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KPI37655.1 - 0.0099 15.6 3.3 0.17 11.6 4.9 1.9 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ilm1 PF10311.9 KPI37655.1 - 0.093 12.4 0.6 0.35 10.5 0.6 1.7 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Sensor PF13796.6 KPI37655.1 - 3.1 7.8 8.2 4.1 7.4 0.3 2.1 1 1 0 2 2 2 0 Putative sensor Sulfotransfer_4 PF17784.1 KPI37656.1 - 3.7e-55 187.1 0.0 1.1e-32 113.6 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI37656.1 - 4.8e-08 33.6 0.2 2.1e-06 28.3 0.2 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KPI37656.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Ras PF00071.22 KPI37657.1 - 1.2e-64 216.8 0.0 1.3e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI37657.1 - 1.2e-33 115.8 0.1 1.7e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI37657.1 - 6.1e-13 48.6 0.0 7.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI37657.1 - 5.3e-05 22.8 0.0 0.0001 21.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI37657.1 - 0.00026 20.4 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KPI37657.1 - 0.0021 18.0 0.1 2.2 8.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KPI37657.1 - 0.0042 17.2 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KPI37657.1 - 0.028 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KPI37657.1 - 0.099 12.2 0.0 0.42 10.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KPI37657.1 - 0.12 12.6 0.1 0.52 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain MOSC PF03473.17 KPI37659.1 - 1.6e-27 96.1 0.0 3.2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPI37659.1 - 3e-11 43.3 0.0 1.7e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF1573 PF07610.11 KPI37659.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) ORC2 PF04084.14 KPI37661.1 - 2.4e-117 391.6 0.0 2.9e-117 391.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 KPI37661.1 - 0.025 13.9 14.3 0.029 13.7 13.3 1.5 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SBE2 PF17076.5 KPI37661.1 - 0.17 10.1 2.6 0.24 9.6 2.6 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation AT_hook PF02178.19 KPI37661.1 - 1.3 9.1 7.6 3.9 7.7 7.6 1.9 1 0 0 1 1 1 0 AT hook motif Rox3 PF08633.10 KPI37662.1 - 1e-48 166.4 0.1 1e-48 166.4 0.1 2.2 2 0 0 2 2 2 1 Rox3 mediator complex subunit ORC6 PF05460.13 KPI37662.1 - 0.39 9.9 15.5 0.1 11.8 12.4 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) MCM_bind PF09739.9 KPI37662.1 - 0.58 8.5 4.6 0.76 8.2 4.6 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PBP1_TM PF14812.6 KPI37662.1 - 7 7.1 19.0 15 6.1 1.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 KPI37662.1 - 8.9 5.0 5.6 12 4.5 5.6 1.2 1 0 0 1 1 1 0 Presenilin SGL PF08450.12 KPI37663.1 - 2.8e-21 76.2 1.4 4e-21 75.7 1.4 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPI37663.1 - 0.014 15.4 0.1 4.3 7.6 0.1 3.6 3 0 0 3 3 3 0 NHL repeat Alpha-L-AF_C PF06964.12 KPI37664.1 - 3.9e-20 72.7 0.0 7.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KPI37664.1 - 0.0034 17.7 0.6 0.0072 16.6 0.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain LAX PF15681.5 KPI37665.1 - 0.011 14.6 0.8 0.019 13.8 0.8 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X RXLR_WY PF18634.1 KPI37665.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain Extensin-like_C PF06904.12 KPI37665.1 - 0.13 12.3 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Extensin-like protein C-terminus Abhydrolase_3 PF07859.13 KPI37666.1 - 5.7e-37 127.6 0.0 7.8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37666.1 - 3e-05 24.7 0.1 4.4e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KPI37666.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPI37666.1 - 0.00026 20.5 0.0 0.48 9.9 0.1 3.0 4 0 0 4 4 4 2 Prolyl oligopeptidase family ADC PF06314.11 KPI37666.1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) Abhydrolase_2 PF02230.16 KPI37666.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PseudoU_synth_1 PF01416.20 KPI37667.1 - 0.071 13.6 0.2 0.23 11.9 0.1 1.9 2 0 0 2 2 2 0 tRNA pseudouridine synthase GvpG PF05120.12 KPI37667.1 - 0.17 11.9 1.7 0.23 11.5 0.3 1.9 2 0 0 2 2 2 0 Gas vesicle protein G pP_pnuc_1 PF18165.1 KPI37667.1 - 0.46 10.4 2.7 1.6 8.6 0.6 2.2 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease ZapB PF06005.12 KPI37667.1 - 4.8 7.7 9.4 3.2 8.3 0.4 2.7 2 1 0 2 2 2 0 Cell division protein ZapB EF1G PF00647.19 KPI37668.1 - 5.7e-45 151.8 0.1 9.9e-45 151.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KPI37668.1 - 1.7e-09 37.9 0.1 2.9e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI37668.1 - 1.1e-07 32.0 0.0 3.7e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI37668.1 - 5.8e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPI37668.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI37668.1 - 0.00045 20.3 0.0 0.0018 18.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI37668.1 - 0.04 14.2 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KPI37668.1 - 3 8.5 6.4 6.3 7.5 6.4 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SAC3_GANP PF03399.16 KPI37669.1 - 5.3e-92 308.3 0.0 8.7e-92 307.6 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family GTP_EFTU PF00009.27 KPI37670.1 - 2.2e-39 135.0 0.0 4.1e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KPI37670.1 - 5.5e-24 84.0 0.0 1.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KPI37670.1 - 4.8e-17 61.8 0.0 5.5e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPI37670.1 - 3.2e-10 40.3 0.0 5.5e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Epimerase PF01370.21 KPI37671.1 - 2.3e-11 43.6 0.2 3.3e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI37671.1 - 3.4e-06 26.3 0.0 6.6e-06 25.3 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPI37671.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KPI37671.1 - 0.0058 15.8 0.0 0.0075 15.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KPI37671.1 - 0.038 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KPI37671.1 - 0.17 11.4 0.0 0.93 9.0 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family NUDIX PF00293.28 KPI37672.1 - 4.2e-15 56.0 0.3 6.3e-15 55.4 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KPI37672.1 - 4.3e-05 23.4 0.1 9.3e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain Aldedh PF00171.22 KPI37673.1 - 1.6e-156 521.5 0.4 1.8e-156 521.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FMO-like PF00743.19 KPI37674.1 - 3.2e-13 48.9 0.0 5.8e-12 44.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI37674.1 - 3.8e-09 36.7 0.0 2.3e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI37674.1 - 1.3e-06 27.9 0.0 0.039 13.2 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI37674.1 - 0.00013 21.7 0.1 0.0031 17.2 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPI37674.1 - 0.0012 18.1 0.1 0.0067 15.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI37674.1 - 0.0056 16.0 0.1 2 7.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI37674.1 - 0.051 13.6 0.0 2.7 8.0 0.0 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding LBR_tudor PF09465.10 KPI37674.1 - 0.11 12.3 0.6 0.32 10.8 0.2 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF4092 PF13322.6 KPI37674.1 - 0.19 11.6 1.4 4.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) DUF3176 PF11374.8 KPI37675.1 - 6.8e-29 100.2 5.5 6.8e-29 100.2 5.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) BCS1_N PF08740.11 KPI37676.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 BCS1 N terminal NUDIX PF00293.28 KPI37677.1 - 2.5e-10 40.5 0.1 7.1e-10 39.0 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain ATG101 PF07855.12 KPI37678.1 - 3.1e-42 144.2 0.0 3.6e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 SPARC_Ca_bdg PF10591.9 KPI37679.1 - 0.071 13.4 3.0 0.6 10.4 2.5 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Rad21_Rec8_N PF04825.13 KPI37680.1 - 7.7e-22 77.5 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KPI37680.1 - 0.0053 16.0 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Nop14 PF04147.12 KPI37680.1 - 9.7 4.3 11.0 16 3.6 11.0 1.3 1 0 0 1 1 1 0 Nop14-like family MT0933_antitox PF14013.6 KPI37681.1 - 0.24 11.7 3.2 0.47 10.8 0.5 2.9 2 0 0 2 2 2 0 MT0933-like antitoxin protein ABATE PF07336.11 KPI37681.1 - 1.4 9.6 10.2 0.41 11.3 4.6 3.1 3 0 0 3 3 3 0 Putative stress-induced transcription regulator Sugar_tr PF00083.24 KPI37682.1 - 3.1e-75 253.8 26.0 3.7e-75 253.5 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37682.1 - 3.1e-14 52.7 36.2 6.3e-13 48.4 34.6 2.4 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KPI37682.1 - 1.7e-05 23.6 23.3 0.00051 18.7 1.9 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein Aa_trans PF01490.18 KPI37683.1 - 6.1e-65 219.5 12.9 7.7e-65 219.2 12.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KPI37683.1 - 0.00019 20.6 9.2 0.00019 20.6 9.2 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3488 PF11992.8 KPI37683.1 - 7.2 5.5 9.3 0.82 8.6 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Cyclase PF04199.13 KPI37684.1 - 1.1e-19 71.0 0.0 2.5e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Putative cyclase DUF641 PF04859.12 KPI37684.1 - 0.0094 16.3 2.4 0.02 15.2 2.4 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Fez1 PF06818.15 KPI37684.1 - 0.02 15.4 2.7 0.02 15.4 2.7 1.8 2 0 0 2 2 2 0 Fez1 Colicin PF01024.19 KPI37684.1 - 0.028 14.3 1.0 0.05 13.5 1.0 1.3 1 0 0 1 1 1 0 Colicin pore forming domain FPP PF05911.11 KPI37684.1 - 0.035 12.3 5.3 0.051 11.8 5.3 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Troponin PF00992.20 KPI37684.1 - 0.047 14.0 1.6 0.1 12.9 1.6 1.5 1 0 0 1 1 1 0 Troponin BLOC1_2 PF10046.9 KPI37684.1 - 0.47 10.8 3.3 0.33 11.3 1.0 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 KPI37684.1 - 9 6.6 9.0 1.3 9.2 4.7 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ferric_reduct PF01794.19 KPI37685.1 - 8.7e-17 61.4 11.9 8.7e-17 61.4 11.9 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPI37685.1 - 3.5e-11 43.5 0.0 7.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI37685.1 - 1e-09 38.5 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KPI37685.1 - 0.24 12.1 0.3 13 6.5 0.0 3.0 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Pex24p PF06398.11 KPI37685.1 - 1.1 8.2 4.9 2.8 6.9 4.9 1.6 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3824 PF12868.7 KPI37685.1 - 9.4 6.9 18.9 0.6 10.8 13.2 2.0 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) TRAF_BIRC3_bd PF16673.5 KPI37686.1 - 0.063 13.1 0.2 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain NPV_P10 PF05531.12 KPI37686.1 - 0.072 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Zn_clus PF00172.18 KPI37687.1 - 3.2e-07 30.3 8.4 5.5e-07 29.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI37687.1 - 0.0076 15.1 0.2 0.011 14.6 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.17 KPI37688.1 - 2.8e-43 148.5 0.0 3.5e-41 141.6 0.1 2.2 2 0 0 2 2 2 2 CoA-transferase family III DUF4387 PF14330.6 KPI37688.1 - 1.8e-37 127.9 0.0 3.7e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KPI37688.1 - 1.7e-17 63.2 0.0 8.8e-17 60.8 0.0 1.9 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA PKcGMP_CC PF16808.5 KPI37689.1 - 0.087 12.7 33.6 2.2 8.2 0.0 7.9 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 KPI37689.1 - 0.46 10.4 0.1 0.46 10.4 0.1 4.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat PhoU PF01895.19 KPI37689.1 - 6.8 7.2 7.1 7.2 7.1 2.6 3.3 2 1 1 3 3 3 0 PhoU domain NIF PF03031.18 KPI37690.1 - 1.5e-10 41.1 0.4 3.3e-10 39.9 0.4 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase 2-Hacid_dh_C PF02826.19 KPI37691.1 - 1.2e-51 174.6 0.0 2e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI37691.1 - 1.4e-36 125.1 0.1 1.9e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KPI37691.1 - 0.0033 17.0 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KPI37691.1 - 0.0035 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 KPI37691.1 - 0.0061 16.3 0.2 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.21 KPI37691.1 - 0.0095 16.0 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KPI37691.1 - 0.015 14.9 0.7 1.6 8.2 0.1 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KPI37691.1 - 0.1 12.4 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KPI37692.1 - 8.4e-10 38.4 0.0 2.2e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI37692.1 - 2.8e-07 30.6 0.0 4.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI37692.1 - 0.00029 20.5 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.6 KPI37693.1 - 6.8e-63 212.4 1.4 8.7e-63 212.0 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI37693.1 - 2.7e-52 177.1 0.4 3.5e-52 176.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI37693.1 - 1.6e-08 34.7 0.5 2.5e-08 34.1 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37693.1 - 0.00072 19.1 0.3 0.00099 18.6 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI37693.1 - 0.00079 18.7 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.16 KPI37693.1 - 0.0043 17.7 0.0 0.0075 16.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KPI37693.1 - 0.0098 16.6 1.2 0.085 13.6 0.2 2.8 2 2 1 3 3 3 1 Methyltransferase domain 3HCDH_N PF02737.18 KPI37693.1 - 0.028 14.3 0.2 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPI37693.1 - 0.031 13.3 0.1 0.058 12.4 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1525 PF07511.11 KPI37693.1 - 0.043 14.0 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) TrkA_N PF02254.18 KPI37693.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Abhydrolase_1 PF00561.20 KPI37695.1 - 9.5e-15 54.9 0.1 2.6e-14 53.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37695.1 - 2.4e-14 54.5 2.1 3.8e-14 53.8 2.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37695.1 - 5.1e-13 48.8 0.0 8.5e-13 48.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KPI37695.1 - 0.086 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SnoaL_2 PF12680.7 KPI37696.1 - 0.02 15.5 0.0 0.025 15.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain 2-Hacid_dh_C PF02826.19 KPI37697.1 - 7.5e-51 172.0 0.0 1.7e-50 170.8 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI37697.1 - 4.4e-16 58.8 0.0 6.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DnaJ_C PF01556.18 KPI37698.1 - 1.5e-36 125.7 0.2 2.2e-36 125.2 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPI37698.1 - 6.2e-22 77.5 1.1 1.2e-21 76.6 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPI37698.1 - 2.9e-14 53.2 19.1 5.3e-14 52.3 19.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KPI37698.1 - 0.071 13.1 20.7 0.92 9.5 6.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KPI37698.1 - 0.13 12.3 7.6 1.4 9.0 0.7 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FdhE PF04216.12 KPI37698.1 - 3.7 7.3 5.6 6.2 6.6 5.6 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Fungal_trans PF04082.18 KPI37700.1 - 3.5e-19 68.9 0.0 7.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37700.1 - 2.3e-09 37.2 9.5 4.5e-09 36.3 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Desmo_N PF06771.11 KPI37700.1 - 0.0027 18.0 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 2 Viral Desmoplakin N-terminus Striatin PF08232.12 KPI37700.1 - 0.0033 18.0 2.2 0.0033 18.0 2.2 1.5 2 0 0 2 2 2 1 Striatin family PSI_integrin PF17205.3 KPI37700.1 - 0.057 13.2 2.1 0.13 12.0 2.1 1.6 1 0 0 1 1 1 0 Integrin plexin domain Zn_clus PF00172.18 KPI37701.1 - 1e-09 38.3 12.6 2e-09 37.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR_2 PF13088.6 KPI37702.1 - 0.00011 21.7 0.0 0.00075 18.9 0.0 2.1 1 1 1 2 2 2 2 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KPI37702.1 - 0.037 12.8 0.3 0.32 9.7 0.2 2.7 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 KPI37702.1 - 5.1 7.5 14.9 3.7 7.9 0.2 4.8 5 0 0 5 5 5 0 BNR/Asp-box repeat K_oxygenase PF13434.6 KPI37703.1 - 4.1e-15 55.8 0.0 2.8e-10 39.9 0.0 3.0 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI37703.1 - 5e-12 45.7 0.0 1.9e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37703.1 - 3.5e-07 29.8 0.0 0.014 14.7 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI37703.1 - 2.7e-06 26.9 0.1 0.054 12.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI37703.1 - 0.00069 19.8 0.6 0.17 12.1 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI37703.1 - 0.00076 20.0 0.1 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI37703.1 - 0.0013 17.8 0.1 0.027 13.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.20 KPI37703.1 - 0.002 18.2 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KPI37703.1 - 0.0049 16.5 2.6 1.7 8.1 0.0 3.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.16 KPI37703.1 - 0.028 14.0 0.0 8.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KPI37703.1 - 0.029 13.1 0.0 0.55 8.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KPI37703.1 - 0.051 13.6 2.0 0.76 9.7 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 KPI37703.1 - 0.063 12.5 0.2 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KPI37703.1 - 0.1 12.8 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain CinA PF02464.17 KPI37704.1 - 4.2e-24 84.9 1.9 1.6e-16 60.3 0.2 2.0 1 1 1 2 2 2 2 Competence-damaged protein MFS_1 PF07690.16 KPI37705.1 - 2.2e-30 105.8 26.1 2.2e-30 105.8 26.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI37705.1 - 3.8e-07 29.7 2.6 3.8e-07 29.7 2.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 KPI37705.1 - 0.0018 17.3 5.5 0.0046 16.0 5.5 1.6 1 0 0 1 1 1 1 PUCC protein DUF1478 PF07349.11 KPI37705.1 - 0.14 12.1 2.4 0.93 9.4 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1478) RRP36 PF06102.12 KPI37706.1 - 2.6e-36 125.1 18.5 4.8e-36 124.2 18.5 1.4 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 RVT_N PF13655.6 KPI37706.1 - 0.043 14.1 1.0 0.087 13.1 1.0 1.5 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase L51_S25_CI-B8 PF05047.16 KPI37707.1 - 2.2e-13 49.9 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Beta_helix PF13229.6 KPI37708.1 - 7.7e-15 55.1 9.5 1.5e-08 34.7 2.9 2.1 2 0 0 2 2 2 2 Right handed beta helix region NosD PF05048.13 KPI37708.1 - 9.4e-10 38.2 8.4 9.5e-07 28.3 0.2 2.7 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) PT-VENN PF04829.13 KPI37708.1 - 7.3 6.8 10.2 1.9 8.6 0.2 3.8 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif RF-1 PF00472.20 KPI37709.1 - 3.3e-23 81.8 0.2 5.1e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain BACK PF07707.15 KPI37710.1 - 0.13 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 BTB And C-terminal Kelch Gly-zipper_Omp PF13488.6 KPI37712.1 - 0.023 14.7 0.7 0.066 13.2 0.0 2.1 2 0 0 2 2 2 0 Glycine zipper NVEALA PF14055.6 KPI37712.1 - 0.087 12.8 3.8 0.59 10.2 0.1 2.8 2 1 0 2 2 2 0 NVEALA protein CD99L2 PF12301.8 KPI37712.1 - 0.12 12.7 0.3 0.12 12.7 0.3 1.5 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF4184 PF13803.6 KPI37712.1 - 0.15 11.7 4.1 0.26 11.0 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) FeoB_associated PF12669.7 KPI37712.1 - 0.18 12.2 3.3 4.1 7.9 0.0 2.8 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein RseC_MucC PF04246.12 KPI37712.1 - 1.5 8.8 6.0 1 9.3 0.2 2.3 1 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1772 PF08592.11 KPI37712.1 - 8.9 6.6 9.4 18 5.6 6.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) GFA PF04828.14 KPI37713.1 - 3.7e-24 84.9 0.3 4.2e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 KPI37714.1 - 1.9e-59 201.2 0.0 2.2e-58 197.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37714.1 - 4.7e-29 101.5 0.1 1.5e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KPI37714.1 - 3e-05 24.6 1.2 8.4e-05 23.2 1.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KPI37714.1 - 4.7e-05 23.4 3.5 0.14 12.0 0.1 3.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI37714.1 - 0.00071 19.0 0.0 0.0027 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KPI37714.1 - 0.033 13.1 0.0 0.063 12.2 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KPI37714.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cut12 PF11500.8 KPI37715.1 - 0.0022 18.0 1.3 0.0022 18.0 1.3 2.0 2 0 0 2 2 2 1 Spindle pole body formation-associated protein Cnn_1N PF07989.11 KPI37715.1 - 0.6 10.3 5.9 9.1 6.5 3.5 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 KLRAQ PF10205.9 KPI37715.1 - 0.8 10.0 6.6 14 6.0 2.0 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DivIC PF04977.15 KPI37715.1 - 2.9 7.7 5.3 40 4.1 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator tRNA-synt_1c PF00749.21 KPI37716.1 - 1.4e-78 264.0 0.0 2e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Glyco_hydro_3 PF00933.21 KPI37717.1 - 6.8e-53 180.1 0.0 1.1e-52 179.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Amidase PF01425.21 KPI37718.1 - 4.2e-100 335.8 0.0 6e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 KPI37719.1 - 5.2e-32 111.1 34.3 5.2e-32 111.1 34.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PDT PF00800.18 KPI37720.1 - 5.8e-28 97.9 0.0 1.7e-07 31.2 0.0 4.0 4 0 0 4 4 4 4 Prephenate dehydratase TNT PF14021.6 KPI37720.1 - 0.042 14.4 0.0 0.084 13.4 0.0 1.5 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin Patatin PF01734.22 KPI37722.1 - 2.7e-07 31.0 0.0 3.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase Carb_anhydrase PF00194.21 KPI37723.1 - 1.6e-24 86.8 0.0 8.5e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AIM5 PF17050.5 KPI37725.1 - 5.4e-17 62.3 0.2 5.4e-17 62.3 0.2 2.6 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 LEA_4 PF02987.16 KPI37725.1 - 3.5e-08 33.4 16.4 4.2e-06 26.7 1.1 2.5 1 1 0 2 2 2 2 Late embryogenesis abundant protein DUF883 PF05957.13 KPI37725.1 - 0.043 14.4 11.0 0.24 12.0 5.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KPI37725.1 - 0.084 12.7 14.8 0.72 9.7 14.8 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3138 PF11336.8 KPI37725.1 - 0.39 9.3 3.2 0.54 8.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) YtxH PF12732.7 KPI37725.1 - 0.67 10.5 15.8 6.7e+02 0.9 15.8 3.0 1 1 0 1 1 1 0 YtxH-like protein TRAF_BIRC3_bd PF16673.5 KPI37725.1 - 3.1 7.6 9.5 2.5 8.0 3.1 3.0 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain ATP-synt_B PF00430.18 KPI37725.1 - 3.7 7.6 15.6 2.1 8.4 12.9 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) ADH_N PF08240.12 KPI37727.1 - 8.7e-19 67.4 0.7 1.7e-18 66.5 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI37727.1 - 8e-08 32.3 0.1 1.5e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SHMT PF00464.19 KPI37728.1 - 1.9e-197 655.7 0.0 2.2e-197 655.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MEDS PF14417.6 KPI37728.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain NAD_binding_6 PF08030.12 KPI37730.1 - 5.6e-19 68.8 0.0 9.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI37730.1 - 1.9e-17 63.3 0.0 4.9e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KPI37730.1 - 6.5e-17 61.8 11.9 1.4e-16 60.7 11.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Fungal_trans PF04082.18 KPI37731.1 - 2.1e-15 56.5 0.1 3.5e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-gua_PtransN PF02807.15 KPI37731.1 - 0.062 13.7 0.1 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain TPR_1 PF00515.28 KPI37731.1 - 0.22 11.4 0.0 6.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 KPI37733.1 - 1.5e-16 60.2 5.4 2.9e-16 59.3 5.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI37733.1 - 1.8e-07 31.2 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI37733.1 - 0.013 14.9 0.2 0.021 14.2 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1640 PF07798.11 KPI37734.1 - 1.3e-30 106.7 7.5 1.3e-30 106.7 7.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) TMEM51 PF15345.6 KPI37734.1 - 0.022 14.6 0.5 0.055 13.3 0.5 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3767 PF12597.8 KPI37734.1 - 0.03 14.1 0.5 0.059 13.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF4407 PF14362.6 KPI37734.1 - 0.22 10.9 9.6 0.36 10.1 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HET PF06985.11 KPI37735.1 - 2.7e-24 86.2 0.4 5.7e-24 85.1 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KPI37735.1 - 1.5e-17 63.7 0.2 5.7e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37735.1 - 1.3e-09 37.9 0.0 0.00047 19.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37735.1 - 0.0032 17.4 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.24 KPI37736.1 - 1.9e-27 96.2 22.5 3.8e-23 82.1 10.4 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KPI37736.1 - 1.8e-24 86.3 27.2 6e-24 84.6 26.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily KilA-N PF04383.13 KPI37737.1 - 0.00013 21.8 0.0 0.0024 17.7 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Ferritin_2 PF13668.6 KPI37739.1 - 3.6e-15 56.4 0.2 5.5e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain BTB PF00651.31 KPI37740.1 - 0.0003 21.0 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain eRF1_2 PF03464.15 KPI37741.1 - 9.2e-48 161.9 0.1 1.6e-47 161.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KPI37741.1 - 3e-37 127.5 0.1 7.6e-37 126.3 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KPI37741.1 - 8.9e-21 74.2 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KPI37741.1 - 1.7e-10 41.3 0.2 5.8e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KPI37741.1 - 2.3e-09 37.6 0.0 6.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1338 PF07063.13 KPI37742.1 - 6.4e-104 347.6 0.0 7.6e-104 347.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) AA_kinase PF00696.28 KPI37742.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family Myosin_head PF00063.21 KPI37744.1 - 2.9e-263 875.1 0.0 6e-263 874.1 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KPI37744.1 - 1.3e-11 44.1 0.5 3.1e-11 42.9 0.5 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.6 KPI37744.1 - 0.058 13.7 0.7 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KPI37744.1 - 0.092 13.0 0.1 0.092 13.0 0.1 4.3 4 3 2 6 6 6 0 AAA domain Spc110_C PF18520.1 KPI37744.1 - 0.14 11.7 0.6 25 4.6 0.0 3.2 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain ORF6N PF10543.9 KPI37744.1 - 0.42 10.8 5.7 15 5.9 0.1 3.6 3 0 0 3 3 3 0 ORF6N domain SET PF00856.28 KPI37745.1 - 5e-12 46.5 0.0 9.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 SET domain THOC2_N PF16134.5 KPI37746.1 - 1.2e-201 671.7 0.0 1.9e-201 671.0 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KPI37746.1 - 1.1e-80 271.0 0.1 2.2e-80 270.1 0.1 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KPI37746.1 - 2.5e-24 85.1 0.0 6e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Sel1 PF08238.12 KPI37748.1 - 9.2e-47 156.4 31.3 6.6e-09 36.2 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat SecY PF00344.20 KPI37749.1 - 1.7e-72 244.3 7.0 2.2e-72 243.9 7.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KPI37749.1 - 2.1e-17 62.7 0.3 6.4e-17 61.1 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p ThiF PF00899.21 KPI37750.1 - 7.1e-27 94.3 0.0 9.7e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KPI37750.1 - 0.077 13.1 0.3 0.22 11.6 0.3 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box PF00646.33 KPI37751.1 - 1.3e-05 24.9 0.5 0.00048 19.9 0.2 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KPI37751.1 - 0.0015 18.3 1.2 0.0029 17.5 0.4 2.0 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.18 KPI37752.1 - 0.00087 19.4 0.5 0.0018 18.3 0.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOR_SNZ PF01680.17 KPI37753.1 - 9.6e-85 283.6 4.9 8.4e-84 280.5 4.9 2.1 1 1 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KPI37753.1 - 5.1e-06 26.0 0.2 5.1e-06 26.0 0.2 2.3 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 KPI37753.1 - 0.0056 15.8 0.3 0.057 12.5 0.1 2.3 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.14 KPI37753.1 - 0.0082 15.4 0.3 0.03 13.5 0.0 2.0 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KPI37753.1 - 0.0083 15.3 0.1 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase MiaE_2 PF13794.6 KPI37753.1 - 0.033 13.9 0.2 0.13 11.9 0.0 2.0 2 1 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like His_biosynth PF00977.21 KPI37753.1 - 0.055 12.9 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein Clp_N PF02861.20 KPI37753.1 - 0.066 13.4 0.3 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component TetR_C_27 PF17935.1 KPI37753.1 - 0.1 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 KPI37753.1 - 1.1 8.6 9.3 0.024 14.1 2.6 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase DEAD PF00270.29 KPI37754.1 - 1.5e-14 54.1 0.1 3.4e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 KPI37754.1 - 4.4e-14 52.7 0.0 1.3e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPI37754.1 - 1.1e-12 48.3 0.0 2.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.14 KPI37754.1 - 0.00015 21.7 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KPI37754.1 - 0.0009 19.5 1.0 0.0055 17.0 0.1 2.6 2 1 1 3 3 3 1 AAA domain Herpes_ori_bp PF02399.15 KPI37754.1 - 0.036 12.1 0.1 0.057 11.5 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Glycos_transf_2 PF00535.26 KPI37755.1 - 3.9e-22 78.9 0.0 1.9e-21 76.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KPI37755.1 - 8.3e-05 22.6 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KPI37755.1 - 0.031 13.7 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KPI37755.1 - 0.2 12.2 0.0 0.65 10.6 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 2 2OG-FeII_Oxy_2 PF13532.6 KPI37756.1 - 6e-33 114.7 0.0 9.7e-32 110.7 0.0 2.0 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily VPDSG-CTERM PF18205.1 KPI37757.1 - 0.22 11.4 1.1 24 4.9 0.0 2.6 2 0 0 2 2 2 0 VPDSG-CTERM motif Rx_N PF18052.1 KPI37758.1 - 0.0012 19.1 0.4 0.0026 18.0 0.4 1.6 1 0 0 1 1 1 1 Rx N-terminal domain SATase_N PF06426.14 KPI37758.1 - 0.074 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal MFS_1 PF07690.16 KPI37759.1 - 9.8e-28 97.1 21.4 2.2e-27 95.9 21.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI37759.1 - 0.00048 18.7 7.9 0.0006 18.4 7.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L17 PF01196.19 KPI37760.1 - 3.5e-31 107.9 0.1 5.6e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 KPI37760.1 - 0.0037 17.5 0.0 0.0097 16.2 0.0 1.7 2 0 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain PspA_IM30 PF04012.12 KPI37761.1 - 0.0031 17.1 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 PspA/IM30 family BTB PF00651.31 KPI37761.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF2841 PF11001.8 KPI37762.1 - 6.7e-32 110.1 2.8 1.4e-31 109.1 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Ctr PF04145.15 KPI37763.1 - 3.2e-31 108.9 0.1 3.9e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2583 PF10762.9 KPI37763.1 - 0.42 11.1 2.8 0.38 11.2 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Peptidase_M41 PF01434.18 KPI37764.1 - 2.1e-68 230.0 0.0 4.4e-68 228.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KPI37764.1 - 5.9e-43 146.5 0.0 1.9e-42 144.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI37764.1 - 4.1e-12 45.7 0.1 1e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KPI37764.1 - 2.3e-10 40.8 0.0 5.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KPI37764.1 - 9.1e-05 22.5 0.0 0.00033 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KPI37764.1 - 0.0021 17.8 0.1 0.048 13.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI37764.1 - 0.003 18.0 0.2 0.25 11.7 0.2 2.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI37764.1 - 0.0066 16.7 0.4 1.2 9.4 0.1 3.4 4 0 0 4 4 4 1 AAA domain TIP49 PF06068.13 KPI37764.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 KPI37764.1 - 0.12 12.8 0.8 0.52 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain TipAS PF07739.13 KPI37764.1 - 0.18 12.4 3.5 10 6.7 0.2 3.6 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain IstB_IS21 PF01695.17 KPI37764.1 - 0.21 11.3 0.5 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 KPI37764.1 - 7.4 6.3 8.3 8.8 6.0 0.1 2.7 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 KPI37765.1 - 1.2 7.9 8.9 0.086 11.8 4.0 1.4 2 0 0 2 2 2 0 Major Facilitator Superfamily 4HBT_3 PF13622.6 KPI37766.1 - 1.1e-38 133.9 0.6 1.3e-38 133.7 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KPI37766.1 - 1.6e-08 34.5 0.1 1.3e-06 28.3 0.2 2.9 2 2 0 2 2 2 1 Acyl-CoA thioesterase PS-DH PF14765.6 KPI37766.1 - 0.011 15.0 0.1 0.12 11.6 0.1 2.6 1 1 0 1 1 1 0 Polyketide synthase dehydratase AfsA PF03756.13 KPI37766.1 - 0.083 12.9 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain Rap_GAP PF02145.15 KPI37767.1 - 1e-38 132.8 0.0 4.9e-38 130.5 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 KPI37767.1 - 7.1e-27 94.4 4.3 8.3e-26 90.9 0.2 2.9 4 0 0 4 4 4 2 Tuberin DUF3384 PF11864.8 KPI37767.1 - 1.1e-19 70.8 2.9 3.9e-19 68.9 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Chitin_synth_1 PF01644.17 KPI37768.1 - 2.9e-50 170.4 0.0 4.8e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KPI37768.1 - 4e-22 78.5 0.5 8.7e-21 74.1 0.4 2.5 1 1 1 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 KPI37768.1 - 3.5e-06 26.9 0.0 8.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal LigB PF02900.18 KPI37769.1 - 1.7e-36 125.7 0.0 2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NUDIX PF00293.28 KPI37770.1 - 5.9e-14 52.2 0.2 2.1e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Zn_clus PF00172.18 KPI37771.1 - 1.8e-09 37.6 9.8 1.8e-09 37.6 9.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KPI37772.1 - 4.8e-74 249.5 0.0 5.6e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI37772.1 - 4.6e-13 49.9 0.0 1e-12 48.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HpcH_HpaI PF03328.14 KPI37773.1 - 2e-29 102.3 1.0 2.7e-29 101.9 1.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KPI37773.1 - 8.1e-05 21.9 0.2 0.00019 20.6 0.2 1.7 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Lipase_GDSL_2 PF13472.6 KPI37773.1 - 0.0099 16.3 0.2 0.015 15.7 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peroxin-3 PF04882.12 KPI37774.1 - 5.1e-125 418.1 0.0 6.5e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 TAP35_44 PF07265.11 KPI37774.1 - 0.01 15.8 1.7 0.048 13.7 1.1 2.2 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 DUF4043 PF13252.6 KPI37774.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) ABC_membrane PF00664.23 KPI37775.1 - 2.1e-81 273.6 24.9 2.6e-43 148.7 9.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI37775.1 - 1.3e-51 174.8 0.1 1.6e-29 103.2 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI37775.1 - 4.1e-10 39.5 7.9 0.0013 18.2 0.1 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KPI37775.1 - 6.1e-05 23.1 1.0 0.24 11.5 0.2 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KPI37775.1 - 8.6e-05 23.1 0.3 0.0048 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI37775.1 - 0.00023 21.1 0.2 0.16 11.9 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KPI37775.1 - 0.00026 20.7 0.8 0.16 11.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KPI37775.1 - 0.0039 17.3 2.1 0.98 9.5 0.0 3.7 4 0 0 4 4 4 1 Dynamin family AAA_16 PF13191.6 KPI37775.1 - 0.0044 17.4 9.0 0.12 12.7 0.2 3.7 4 0 0 4 4 4 2 AAA ATPase domain DUF87 PF01935.17 KPI37775.1 - 0.0074 16.4 2.1 1.6 8.8 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 KPI37775.1 - 0.017 15.0 3.8 0.5 10.1 0.1 3.1 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KPI37775.1 - 0.041 13.6 6.8 0.035 13.8 0.5 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 KPI37775.1 - 0.11 12.2 0.6 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KPI37775.1 - 0.12 12.7 2.2 15 5.8 0.1 3.8 4 0 0 4 4 4 0 AAA domain DUF3381 PF11861.8 KPI37775.1 - 0.13 12.1 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AAA_7 PF12775.7 KPI37775.1 - 0.14 11.6 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPI37775.1 - 0.15 12.4 0.0 5.9 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.16 KPI37775.1 - 7.4 5.8 5.9 6.6 6.0 0.1 2.8 3 0 0 3 3 3 0 AIG1 family NAT PF04768.13 KPI37776.1 - 5.1e-45 153.2 0.5 2.3e-43 147.8 0.1 2.7 2 1 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KPI37776.1 - 4.3e-32 111.1 0.0 1.4e-31 109.4 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KPI37776.1 - 5.4e-29 101.5 0.0 1e-28 100.6 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KPI37776.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3361 PF11841.8 KPI37776.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Arm PF00514.23 KPI37776.1 - 0.15 12.1 0.1 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat D123 PF07065.14 KPI37777.1 - 4.9e-106 354.3 0.2 6.7e-106 353.9 0.2 1.2 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 KPI37777.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Gcn1_N PF12074.8 KPI37778.1 - 2.3e-73 247.5 4.4 3e-73 247.2 0.2 3.6 5 0 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KPI37778.1 - 1.7e-20 71.4 59.5 0.24 11.8 0.0 23.5 28 0 0 28 28 24 7 HEAT repeat HEAT_2 PF13646.6 KPI37778.1 - 4.2e-20 71.9 65.6 1.2e-05 25.6 0.1 18.0 12 4 7 20 20 19 7 HEAT repeats HEAT_EZ PF13513.6 KPI37778.1 - 2.6e-19 69.3 40.3 4.4e-07 30.3 0.0 17.1 17 2 2 19 19 17 3 HEAT-like repeat Cnd1 PF12717.7 KPI37778.1 - 8.3e-17 61.7 7.7 0.24 11.4 0.3 10.6 7 2 4 11 11 11 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPI37778.1 - 3e-13 50.2 0.0 0.45 11.1 0.0 9.2 7 3 4 11 11 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KPI37778.1 - 4.4e-10 39.5 0.4 0.24 10.9 0.0 7.6 7 1 1 8 8 8 2 CLASP N terminal ParcG PF10274.9 KPI37778.1 - 1.4e-09 38.3 4.4 0.0094 16.1 0.1 7.2 8 2 1 9 9 8 2 Parkin co-regulated protein TIP120 PF08623.10 KPI37778.1 - 6.6e-05 22.7 0.1 0.05 13.4 0.0 5.0 3 2 1 4 4 4 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 KPI37778.1 - 0.00029 19.6 9.5 20 3.6 0.0 7.3 5 2 0 7 7 7 0 Adaptin N terminal region DUF3385 PF11865.8 KPI37778.1 - 0.00092 19.2 1.0 2.1 8.3 0.0 5.5 4 2 0 5 5 5 1 Domain of unknown function (DUF3385) Ecm29 PF13001.7 KPI37778.1 - 0.013 14.2 1.3 0.23 10.1 0.0 3.4 3 1 0 3 3 3 0 Proteasome stabiliser RTP1_C1 PF10363.9 KPI37778.1 - 0.019 15.2 1.9 8.4 6.6 0.0 5.5 6 0 0 6 6 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KPI37778.1 - 0.039 14.0 12.9 18 5.5 0.0 7.4 7 1 1 8 8 6 0 Armadillo/beta-catenin-like repeat SEN1_N PF12726.7 KPI37778.1 - 0.04 12.1 0.2 10 4.2 0.0 3.0 2 1 1 3 3 3 0 SEN1 N terminal SPG48 PF14764.6 KPI37778.1 - 0.049 14.1 0.1 21 5.6 0.0 3.7 4 0 0 4 4 3 0 AP-5 complex subunit, vesicle trafficking Cohesin_HEAT PF12765.7 KPI37778.1 - 0.051 13.9 0.5 4 7.8 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HTH_32 PF13565.6 KPI37778.1 - 0.22 12.2 1.0 1.3 9.7 1.0 2.4 1 0 0 1 1 1 0 Homeodomain-like domain TFCD_C PF12612.8 KPI37778.1 - 0.34 10.7 5.4 3.5 7.4 0.1 4.3 5 1 0 5 5 4 0 Tubulin folding cofactor D C terminal MMS19_C PF12460.8 KPI37778.1 - 0.66 9.0 13.7 2.3 7.2 1.0 6.0 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal WSC PF01822.19 KPI37779.1 - 8.7e-52 173.2 58.4 6.9e-18 64.6 11.3 3.9 4 0 0 4 4 4 3 WSC domain PAN_4 PF14295.6 KPI37779.1 - 0.0084 16.0 4.1 0.0084 16.0 4.1 7.2 8 0 0 8 8 8 1 PAN domain Fungal_lectin_2 PF18647.1 KPI37780.1 - 0.067 13.7 0.3 0.08 13.4 0.3 1.2 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin zf-Di19 PF05605.12 KPI37781.1 - 0.015 15.6 0.2 0.027 14.8 0.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KPI37781.1 - 0.034 15.0 0.4 0.11 13.4 0.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KPI37781.1 - 0.035 14.0 0.4 0.063 13.2 0.4 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Glyoxalase PF00903.25 KPI37782.1 - 1.3e-11 44.8 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KPI37782.1 - 0.0093 16.8 0.0 0.031 15.1 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain CAS_CSE1 PF03378.15 KPI37783.1 - 1.8e-165 550.7 0.0 6e-165 549.0 0.0 1.9 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KPI37783.1 - 8.2e-143 475.7 1.6 1.3e-142 475.0 1.6 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KPI37783.1 - 3.3e-15 55.7 0.1 2.1e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KPI37783.1 - 0.0082 16.2 0.5 0.11 12.6 0.0 3.3 3 1 0 3 3 3 1 Exportin 1-like protein V-ATPase_H_N PF03224.14 KPI37783.1 - 0.013 14.8 0.1 0.088 12.1 0.0 2.3 2 1 1 3 3 3 0 V-ATPase subunit H DUF2604 PF10790.9 KPI37783.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) DUF3632 PF12311.8 KPI37784.1 - 9.2e-20 71.8 0.1 1.3e-19 71.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) NAD_binding_4 PF07993.12 KPI37785.1 - 4.5e-34 117.8 0.0 6.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KPI37785.1 - 6.2e-23 81.1 0.0 9.7e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KPI37785.1 - 3.4e-10 39.8 0.0 8.4e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KPI37785.1 - 2.1e-05 24.8 0.1 4.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KPI37785.1 - 0.0021 18.0 0.0 0.0086 16.0 0.0 2.0 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI37785.1 - 0.0027 17.2 0.0 0.047 13.1 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF5575 PF17738.1 KPI37785.1 - 0.014 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) BTB PF00651.31 KPI37787.1 - 1.5e-05 25.2 0.1 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain DUF229 PF02995.17 KPI37787.1 - 0.2 10.2 0.1 0.3 9.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) BRCT_2 PF16589.5 KPI37788.1 - 1.2e-09 38.4 0.0 2.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Zn_clus PF00172.18 KPI37788.1 - 5.8e-07 29.5 12.8 9.6e-07 28.8 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.26 KPI37788.1 - 0.0036 17.6 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KPI37788.1 - 0.011 15.6 0.6 0.057 13.4 0.6 2.3 2 1 0 2 2 2 0 twin BRCT domain SPX PF03105.19 KPI37788.1 - 0.034 14.1 1.6 0.066 13.1 1.6 1.4 1 0 0 1 1 1 0 SPX domain LIG3_BRCT PF16759.5 KPI37788.1 - 0.095 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain HATPase_c PF02518.26 KPI37789.1 - 1.7e-22 80.1 0.1 4.1e-22 78.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI37789.1 - 9.1e-19 67.7 0.0 3.5e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KPI37789.1 - 1.9e-12 47.0 0.0 4.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KPI37789.1 - 0.00013 22.6 0.0 0.0026 18.4 0.0 2.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KPI37789.1 - 0.006 16.9 0.0 0.02 15.2 0.0 2.0 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 KPI37789.1 - 0.024 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KPI37789.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain adh_short_C2 PF13561.6 KPI37790.1 - 4.1e-59 200.0 2.2 4.9e-59 199.7 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI37790.1 - 2.2e-43 148.0 1.5 2.7e-43 147.7 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI37790.1 - 3.4e-09 36.9 3.0 4.8e-09 36.4 3.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPI37790.1 - 8e-05 22.6 0.5 0.00015 21.7 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KPI37790.1 - 0.00012 21.6 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI37790.1 - 0.00017 21.2 0.6 0.00025 20.6 0.6 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI37790.1 - 0.0013 17.9 0.2 0.002 17.3 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KPI37790.1 - 0.0022 17.4 0.1 0.0048 16.2 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_25 PF13649.6 KPI37790.1 - 0.0072 17.0 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KPI37790.1 - 0.01 15.4 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.19 KPI37790.1 - 0.015 14.3 1.0 0.036 13.1 0.8 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPI37790.1 - 0.023 14.6 3.3 0.019 14.8 1.2 1.9 2 0 0 2 2 2 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI37790.1 - 0.11 12.7 1.2 0.21 11.9 1.2 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ArfGap PF01412.18 KPI37791.1 - 1e-29 103.0 0.9 1.8e-29 102.2 0.2 1.8 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf MPC PF03650.13 KPI37792.1 - 1.3e-43 147.6 0.3 2.1e-43 146.9 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KPI37792.1 - 0.05 13.6 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Marek_SORF3 PF07153.11 KPI37792.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein TauD PF02668.16 KPI37793.1 - 2.8e-51 174.9 1.5 3.3e-51 174.6 1.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BTB PF00651.31 KPI37796.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain RFX_DNA_binding PF02257.15 KPI37797.1 - 3.9e-26 91.5 0.0 3.9e-26 91.5 0.0 2.4 3 0 0 3 3 3 1 RFX DNA-binding domain ArgJ PF01960.18 KPI37798.1 - 2.6e-149 497.0 2.0 3e-149 496.8 2.0 1.0 1 0 0 1 1 1 1 ArgJ family Coat_F PF07875.12 KPI37799.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Coat F domain p450 PF00067.22 KPI37800.1 - 2.4e-66 224.4 0.0 3e-41 141.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_1 PF00667.20 KPI37800.1 - 4.4e-29 101.6 0.1 6.9e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPI37800.1 - 1.8e-18 67.2 0.0 4.2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPI37800.1 - 1.4e-13 51.5 0.0 6.6e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPI37800.1 - 6.5e-05 23.2 0.1 0.0051 17.1 0.0 2.9 2 1 1 3 3 3 1 Oxidoreductase FAD-binding domain SBP_bac_5 PF00496.22 KPI37800.1 - 0.027 13.5 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Synaptobrevin PF00957.21 KPI37801.1 - 2.4e-12 46.4 2.5 3.1e-12 46.1 2.5 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF1035 PF06281.12 KPI37801.1 - 0.14 12.2 3.0 0.23 11.5 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Glyco_hydro_3_C PF01915.22 KPI37802.1 - 2.6e-46 158.1 0.0 7.3e-46 156.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPI37802.1 - 3e-17 62.5 0.7 7.8e-17 61.2 0.7 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPI37802.1 - 3e-09 36.8 0.0 7.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KPI37802.1 - 0.00035 20.8 1.0 0.01 16.1 0.1 3.1 3 1 0 3 3 3 1 CARDB SSURE PF11966.8 KPI37802.1 - 0.16 11.8 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Fibronectin-binding repeat BTB PF00651.31 KPI37803.1 - 0.005 17.0 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KPI37804.1 - 8.1e-05 22.8 1.0 0.28 11.4 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain Cu-oxidase_2 PF07731.14 KPI37805.1 - 7e-42 142.4 6.7 8.3e-42 142.2 0.3 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KPI37805.1 - 5.5e-27 94.1 3.5 1.5e-26 92.7 0.4 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KPI37805.1 - 1.2e-23 84.0 0.1 7.3e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_10 PF00331.20 KPI37806.1 - 4.1e-95 318.6 0.0 4.7e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Erf4 PF10256.9 KPI37807.1 - 1.2e-05 25.4 0.0 3.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF3584 PF12128.8 KPI37807.1 - 0.035 11.6 11.5 0.048 11.2 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMCO5 PF14992.6 KPI37807.1 - 1.6 8.3 9.7 3.1 7.3 9.7 1.4 1 0 0 1 1 1 0 TMCO5 family TAtT PF16811.5 KPI37807.1 - 1.8 7.8 7.5 0.29 10.4 3.2 1.7 1 1 0 1 1 1 0 TRAP transporter T-component Ferlin_C PF16165.5 KPI37807.1 - 8.8 6.3 6.6 15 5.5 6.6 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Methyltransf_23 PF13489.6 KPI37808.1 - 6e-14 52.2 0.0 8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI37808.1 - 1.7e-07 31.9 0.0 7.1e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI37808.1 - 1.9e-06 28.4 0.0 4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI37808.1 - 2.5e-05 24.9 0.0 3.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI37808.1 - 0.004 17.0 0.0 0.0081 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GET2 PF08690.10 KPI37809.1 - 0.65 9.6 6.8 0.77 9.4 6.8 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Pneumo_att_G PF05539.11 KPI37809.1 - 0.86 9.1 16.0 1 8.9 16.0 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Gln-synt_C PF00120.24 KPI37810.1 - 6.6e-86 288.4 0.0 7.8e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain HEAT_2 PF13646.6 KPI37810.1 - 0.083 13.3 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats TB2_DP1_HVA22 PF03134.19 KPI37811.1 - 2.2e-26 91.6 8.8 3.5e-26 90.9 8.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Zn_clus PF00172.18 KPI37813.1 - 2.4e-06 27.6 8.9 2.4e-06 27.6 8.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI37813.1 - 0.011 14.5 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Rit1_C PF17184.4 KPI37814.1 - 1e-73 248.2 0.0 1.5e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KPI37814.1 - 1.8e-30 105.5 0.0 3.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Sugar_tr PF00083.24 KPI37815.1 - 1.4e-17 63.7 25.2 2.1e-06 26.9 5.4 3.6 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KPI37815.1 - 3.4e-16 59.1 30.5 4.5e-12 45.6 9.2 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sacchrp_dh_C PF16653.5 KPI37816.1 - 1.5e-95 320.3 0.0 2.5e-95 319.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KPI37816.1 - 8.4e-24 84.3 0.2 1.4e-23 83.6 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KPI37816.1 - 2.4e-07 30.9 0.1 4.8e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KPI37816.1 - 9.3e-05 22.4 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 KPI37816.1 - 0.0055 16.0 0.1 0.0093 15.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KPI37816.1 - 0.027 14.9 0.1 0.063 13.7 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.12 KPI37816.1 - 0.035 13.7 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_3 PF03447.16 KPI37816.1 - 0.051 14.2 0.1 0.094 13.4 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KPI37818.1 - 3.2e-16 59.2 0.0 5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37818.1 - 3.2e-08 33.6 8.0 7e-08 32.5 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI37820.1 - 2.7e-20 72.5 0.5 2.7e-20 72.5 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37820.1 - 1.9e-05 24.6 9.1 4.4e-05 23.5 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L27 PF01016.19 KPI37821.1 - 1.3e-15 57.2 1.0 7e-15 54.8 0.8 2.2 1 1 1 2 2 2 1 Ribosomal L27 protein Y_phosphatase3 PF13350.6 KPI37822.1 - 3e-54 184.5 0.0 3.6e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KPI37822.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KPI37822.1 - 0.0055 16.3 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KPI37822.1 - 0.04 14.0 0.0 0.093 12.8 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate ANAPC3 PF12895.7 KPI37824.1 - 2.1e-24 85.5 15.5 6.3e-20 71.2 0.4 5.6 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KPI37824.1 - 2.6e-21 74.0 14.8 0.0031 17.5 0.2 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KPI37824.1 - 2.6e-21 74.5 5.2 0.0013 18.5 0.2 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KPI37824.1 - 1.2e-17 64.1 6.6 0.00018 22.0 0.0 6.1 5 1 1 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 KPI37824.1 - 1.3e-15 57.4 25.6 1.8e-08 34.5 0.5 8.5 7 2 1 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI37824.1 - 1.7e-12 46.5 5.8 0.14 12.4 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPI37824.1 - 2e-10 40.6 17.9 0.57 11.2 0.1 9.4 7 3 3 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPI37824.1 - 5.5e-09 35.6 14.8 0.00029 20.6 0.9 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI37824.1 - 7.4e-08 32.9 16.7 0.29 11.8 0.0 7.2 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPI37824.1 - 1.1e-06 28.3 0.5 4.5 7.0 0.0 5.9 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 KPI37824.1 - 9.6e-05 22.2 24.3 0.77 9.9 0.0 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI37824.1 - 0.0068 16.7 0.1 34 5.1 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI37824.1 - 0.0078 16.8 14.2 5.3 7.9 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KPI37824.1 - 0.016 15.2 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 0 Putative TPR-like repeat DUF1087 PF06465.13 KPI37824.1 - 0.062 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) TPR_15 PF13429.6 KPI37824.1 - 0.11 11.7 6.2 8.2 5.5 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat FAA_hydrolase_N PF09298.11 KPI37824.1 - 0.13 12.4 0.2 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal Mannosyl_trans2 PF04188.13 KPI37825.1 - 1.3e-45 156.5 13.2 5.6e-43 147.9 13.2 2.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Pro_CA PF00484.19 KPI37826.1 - 1.9e-38 132.2 0.0 2.3e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase MMgT PF10270.9 KPI37827.1 - 4.7e-25 87.8 0.0 5.8e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter ADH_N_2 PF16884.5 KPI37828.1 - 2.2e-30 104.7 0.2 4.4e-30 103.8 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KPI37828.1 - 6.8e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DJ-1_PfpI PF01965.24 KPI37830.1 - 8e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KPI37830.1 - 0.057 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Nitroreductase PF00881.24 KPI37832.1 - 1.8e-12 47.6 0.0 2.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF2625 PF10946.8 KPI37832.1 - 0.084 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Pyrid_ox_like PF16242.5 KPI37833.1 - 3.2e-24 85.2 0.0 5.4e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KPI37833.1 - 2.9e-07 30.6 0.0 5.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase V_ATPase_I PF01496.19 KPI37834.1 - 0 1074.7 0.8 0 1074.5 0.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.21 KPI37834.1 - 0.0058 16.3 4.3 0.92 9.0 1.4 2.2 2 0 0 2 2 2 2 Intermediate filament protein CheZ PF04344.13 KPI37834.1 - 0.02 14.8 3.5 0.04 13.8 0.2 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Serine_rich PF08824.10 KPI37834.1 - 0.025 14.6 0.9 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.12 KPI37834.1 - 0.13 12.3 1.5 0.62 10.1 0.3 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1218 PF06749.12 KPI37834.1 - 0.24 11.9 6.9 0.92 10.1 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) LidA_Long_CC PF18641.1 KPI37834.1 - 0.32 11.1 1.5 9.3 6.3 0.2 2.3 2 0 0 2 2 2 0 LidA long coiled-coil domain HMMR_N PF15905.5 KPI37834.1 - 1.3 8.5 5.2 5.9 6.3 0.6 2.4 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Prefoldin_2 PF01920.20 KPI37834.1 - 1.3 9.0 4.3 3.2 7.7 0.8 2.9 3 0 0 3 3 3 0 Prefoldin subunit TACC_C PF05010.14 KPI37834.1 - 2.7 7.8 5.4 6.9 6.4 2.2 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 KPI37834.1 - 5.3 7.7 5.3 14 6.4 0.2 2.9 3 0 0 3 3 3 0 SlyX PRELI PF04707.14 KPI37835.1 - 3.1e-41 140.8 0.1 3.7e-41 140.6 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family ACOX PF01756.19 KPI37836.1 - 1.4e-46 158.3 0.2 2.7e-46 157.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KPI37836.1 - 1.4e-29 103.2 0.4 3.2e-29 102.0 0.4 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPI37836.1 - 3.7e-11 43.1 0.0 7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KPI37836.1 - 3.1e-05 24.2 0.0 0.0073 16.5 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain GUCT PF08152.12 KPI37836.1 - 0.026 14.8 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 GUCT (NUC152) domain LepB_N PF18640.1 KPI37836.1 - 0.039 13.6 0.2 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 LepB N-terminal domain 7TMR-HDED PF07697.11 KPI37836.1 - 0.091 12.9 0.2 0.88 9.6 0.0 2.1 2 0 0 2 2 2 0 7TM-HD extracellular Mito_carr PF00153.27 KPI37837.1 - 8.7e-45 150.6 0.8 4e-17 61.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 KPI37838.1 - 4.8e-67 226.8 21.2 6e-67 226.5 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI37838.1 - 6.5e-15 54.9 37.0 4.5e-12 45.6 14.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Filo_VP35 PF02097.15 KPI37840.1 - 0.042 12.9 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Filoviridae VP35 FUSC_2 PF13515.6 KPI37841.1 - 0.11 12.6 0.0 0.45 10.6 0.0 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein-like DUF3342 PF11822.8 KPI37842.1 - 0.044 14.0 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) PE_PPE_C PF12484.8 KPI37842.1 - 8.7 7.3 7.9 6.9e+02 1.3 7.6 2.2 1 1 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal Dna2 PF08696.11 KPI37843.1 - 2.9e-61 206.8 0.0 5.7e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KPI37843.1 - 2.2e-53 180.9 0.0 1.6e-52 178.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KPI37843.1 - 1.2e-31 110.4 5.1 8.7e-17 61.8 0.0 3.4 3 1 1 4 4 3 2 AAA domain AAA_30 PF13604.6 KPI37843.1 - 2.8e-18 66.3 0.0 6.3e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI37843.1 - 5.4e-13 49.5 0.1 1.6e-12 48.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPI37843.1 - 4.6e-08 33.1 0.4 0.33 10.6 0.1 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 KPI37843.1 - 8e-08 32.6 0.4 4.2e-07 30.2 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 SRP54 PF00448.22 KPI37843.1 - 0.0003 20.5 0.1 0.00089 18.9 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KPI37843.1 - 0.00054 19.6 0.1 0.0016 18.0 0.1 1.8 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KPI37843.1 - 0.0017 18.2 0.0 0.0054 16.6 0.0 1.9 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 KPI37843.1 - 0.0032 16.7 0.1 0.025 13.7 0.1 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KPI37843.1 - 0.0065 16.9 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KPI37843.1 - 0.0098 15.9 0.4 0.026 14.6 0.4 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KPI37843.1 - 0.023 14.0 0.0 0.058 12.6 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KPI37843.1 - 0.025 14.1 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 KPI37843.1 - 0.042 13.9 2.7 0.11 12.6 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain ResIII PF04851.15 KPI37843.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KPI37843.1 - 0.05 13.4 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RuvB_N PF05496.12 KPI37843.1 - 0.062 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KPI37843.1 - 0.068 13.1 0.2 0.26 11.2 0.2 1.9 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 KPI37843.1 - 0.088 13.4 0.0 0.43 11.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain MobB PF03205.14 KPI37843.1 - 0.11 12.5 0.1 0.38 10.6 0.1 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1413 PF07205.11 KPI37843.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) AAA PF00004.29 KPI37843.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI37843.1 - 0.2 11.9 0.4 1.6 9.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain TPP_enzyme_N PF02776.18 KPI37844.1 - 3.5e-37 127.6 0.2 1e-36 126.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPI37844.1 - 1.8e-23 83.0 0.1 6.4e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI37844.1 - 9.9e-21 73.9 0.0 1.7e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M18 PF02127.15 KPI37845.1 - 2.6e-121 405.4 0.0 3.7e-119 398.3 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KPI37845.1 - 0.0066 15.5 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase TOM13 PF08219.11 KPI37846.1 - 1.7e-34 117.6 0.0 2.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Epiglycanin_C PF14654.6 KPI37846.1 - 0.048 13.7 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region UBA PF00627.31 KPI37847.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain KBP_C PF12309.8 KPI37847.1 - 0.098 12.2 0.4 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Peptidase_M43 PF05572.13 KPI37848.1 - 1.2e-08 35.0 3.1 3.5e-07 30.3 3.1 2.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 KPI37848.1 - 3.7e-05 23.5 0.1 7.5e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KPI37848.1 - 5.1e-05 23.5 1.2 0.00011 22.4 1.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KPI37848.1 - 0.00075 20.0 0.0 0.0018 18.8 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KPI37848.1 - 0.0034 17.3 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KPI37848.1 - 0.005 16.7 0.0 0.0088 15.9 0.0 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KPI37848.1 - 0.09 11.7 0.4 0.25 10.3 0.1 1.7 2 0 0 2 2 2 0 Peptidase M66 MFS_1 PF07690.16 KPI37849.1 - 1.6e-22 79.9 51.0 2.3e-19 69.5 37.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 KPI37851.1 - 3.3e-11 43.2 0.0 2.3e-10 40.5 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI37851.1 - 8.8e-08 32.4 0.1 2.7e-07 30.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI37851.1 - 1e-07 32.3 0.0 4.9e-07 30.1 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI37851.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KPI37851.1 - 0.0011 19.1 0.0 0.079 13.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KPI37851.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 MOZ/SAS family Thiolase_N PF00108.23 KPI37852.1 - 1.5e-13 50.7 0.1 2.7e-11 43.3 0.0 3.1 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI37852.1 - 1.6e-10 40.7 1.0 1.2e-09 37.9 0.2 2.6 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KPI37852.1 - 2e-07 30.7 0.0 2.9e-05 23.8 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KPI37852.1 - 0.00013 21.7 0.6 0.00045 19.9 0.1 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPI37852.1 - 0.022 14.8 0.1 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 KPI37852.1 - 0.076 11.7 0.1 0.17 10.6 0.1 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Aldo_ket_red PF00248.21 KPI37854.1 - 3.1e-37 128.4 0.0 3.5e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase PF00144.24 KPI37855.1 - 1.1e-34 120.2 2.4 2e-34 119.4 2.4 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KPI37855.1 - 5e-07 30.1 0.0 2.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) CTP_transf_like PF01467.26 KPI37856.1 - 8.4e-25 87.6 0.0 1e-19 71.1 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like TrkH PF02386.16 KPI37857.1 - 2.9e-151 504.3 2.1 3.7e-150 500.7 1.9 2.1 2 0 0 2 2 2 2 Cation transport protein LPD23 PF18838.1 KPI37857.1 - 0.11 12.3 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 adh_short PF00106.25 KPI37858.1 - 1.3e-31 109.5 0.1 1.9e-29 102.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI37858.1 - 7.9e-25 87.8 0.0 8.1e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI37858.1 - 6.8e-09 35.9 1.1 1.1e-07 32.0 1.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37858.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI37858.1 - 0.12 11.4 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Meth_synt_2 PF01717.18 KPI37859.1 - 1.1e-10 41.3 0.0 1.9e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPI37859.1 - 0.0099 15.4 0.0 0.023 14.2 0.0 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain DUF3512 PF12024.8 KPI37859.1 - 0.16 11.5 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) adh_short PF00106.25 KPI37860.1 - 6.9e-18 64.8 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI37860.1 - 1.1e-10 41.7 0.0 2.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI37860.1 - 1.2e-06 28.3 0.0 2.6e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI37860.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2855 PF11017.8 KPI37861.1 - 5.7e-74 249.9 0.0 6.7e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Glutaredoxin PF00462.24 KPI37862.1 - 9.8e-17 60.9 0.0 1.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin SEP PF08059.13 KPI37863.1 - 1.9e-24 86.0 0.2 1.2e-23 83.4 0.0 2.2 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 KPI37863.1 - 5.5e-12 45.3 0.2 9.7e-12 44.5 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KPI37863.1 - 3e-11 43.4 0.0 4.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain DUF3530 PF12048.8 KPI37864.1 - 0.066 12.6 1.0 0.07 12.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 KPI37865.1 - 7.2e-45 153.4 0.0 1.1e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI37865.1 - 2.4e-07 30.0 0.2 9e-07 28.1 0.1 1.9 1 1 1 2 2 2 1 Carboxylesterase family Esterase_phd PF10503.9 KPI37865.1 - 0.061 12.8 1.1 1.3 8.5 0.2 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase MFS_1 PF07690.16 KPI37866.1 - 2.1e-24 86.1 42.1 4.5e-24 85.0 40.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI37866.1 - 0.0095 14.8 0.1 0.0095 14.8 0.1 2.2 2 0 0 2 2 2 1 MFS_1 like family Fe-ADH PF00465.19 KPI37867.1 - 8.2e-55 186.1 0.2 2.5e-29 102.2 0.2 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPI37867.1 - 2e-05 24.4 0.9 0.0081 15.9 0.1 3.0 2 1 1 3 3 3 2 Iron-containing alcohol dehydrogenase SIR2 PF02146.17 KPI37868.1 - 5.9e-37 127.3 0.0 8.3e-26 91.0 0.0 2.3 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KPI37868.1 - 3.2e-05 23.7 0.0 0.051 13.3 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Adap_comp_sub PF00928.21 KPI37869.1 - 9.5e-71 238.2 0.0 2.1e-63 214.1 0.0 2.2 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPI37869.1 - 4.8e-09 36.3 0.2 8e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5572 PF17733.1 KPI37870.1 - 1.8e-17 62.9 1.4 2.5e-17 62.5 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5572) DAO PF01266.24 KPI37872.1 - 3.3e-47 161.8 0.1 3.7e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPI37872.1 - 0.0069 15.7 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KPI37872.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI37872.1 - 0.7 8.9 4.2 6 5.8 4.2 2.0 1 1 0 1 1 1 0 FAD binding domain Iso_dh PF00180.20 KPI37874.1 - 4.8e-99 331.8 0.0 5.9e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KPI37874.1 - 0.07 13.2 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Nop52 PF05997.12 KPI37875.1 - 9.8e-36 123.6 0.2 1.3e-35 123.1 0.2 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Mitofilin PF09731.9 KPI37875.1 - 0.2 10.4 5.8 0.3 9.9 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF908 PF06012.12 KPI37875.1 - 2.2 7.6 9.9 3.3 7.0 9.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ATP11 PF06644.11 KPI37875.1 - 7.6 6.2 8.0 8.2 6.1 6.4 1.8 1 1 1 2 2 2 0 ATP11 protein Fungal_trans PF04082.18 KPI37876.1 - 7.4e-44 149.8 0.3 1.2e-43 149.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37876.1 - 6.6e-09 35.8 7.2 1.2e-08 34.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc_ribbon_16 PF17034.5 KPI37876.1 - 0.08 13.2 0.9 0.76 10.0 0.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon like family PHD PF00628.29 KPI37876.1 - 0.28 11.1 3.7 0.6 10.0 3.7 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_16 PF00722.21 KPI37877.1 - 0.00044 19.8 0.1 0.00091 18.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF108 PF01958.18 KPI37878.1 - 0.024 15.0 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF108 Ribosomal_L40e PF01020.17 KPI37880.1 - 1.5e-32 111.3 12.0 1.8e-32 111.0 12.0 1.1 1 0 0 1 1 1 1 Ribosomal L40e family Methyltr_RsmB-F PF01189.17 KPI37881.1 - 1e-73 247.3 0.0 1.8e-73 246.5 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KPI37881.1 - 5.2e-07 30.1 0.0 1.4e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KPI37881.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase CBM77 PF18283.1 KPI37881.1 - 0.031 14.7 1.0 0.074 13.4 1.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding module 77 ATP_synth_reg PF14960.6 KPI37882.1 - 0.15 11.5 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 ATP synthase regulation COesterase PF00135.28 KPI37883.1 - 3.1e-88 296.9 0.0 3.9e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI37883.1 - 0.00024 21.0 0.0 0.0053 16.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 KPI37884.1 - 1.6e-66 224.4 0.0 2.4e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37884.1 - 3.5e-47 160.9 0.0 5.4e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI37884.1 - 3.4e-05 22.8 0.0 3.4e-05 22.8 0.0 3.0 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KPI37884.1 - 0.012 15.0 0.1 0.041 13.2 0.0 1.9 2 1 0 2 2 2 0 Kinase-like ABC1 PF03109.16 KPI37884.1 - 0.025 14.7 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family PEP-utilizers PF00391.23 KPI37884.1 - 0.11 12.3 0.3 7.3 6.4 0.0 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain Fungal_trans PF04082.18 KPI37886.1 - 1.2e-12 47.5 0.8 2e-12 46.7 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IMS PF00817.20 KPI37886.1 - 0.042 13.8 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family DUF819 PF05684.12 KPI37886.1 - 0.13 11.2 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF819) Ig_GlcNase PF18368.1 KPI37887.1 - 3.5e-31 107.5 0.1 8.4e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KPI37887.1 - 2.7e-10 40.9 0.0 9.4e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KPI37887.1 - 4.1e-07 30.1 0.3 1.2e-06 28.6 0.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KPI37887.1 - 0.0023 17.1 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 KPI37887.1 - 0.034 13.9 1.6 0.3 10.9 0.1 2.9 3 0 0 3 3 3 0 Ig-fold domain TfoX_C PF04994.13 KPI37887.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 TfoX C-terminal domain SoxZ PF08770.11 KPI37887.1 - 0.1 12.4 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ bZIP_1 PF00170.21 KPI37888.1 - 2.8e-08 33.7 14.1 9e-08 32.1 13.5 2.0 1 1 1 2 2 2 1 bZIP transcription factor ATG16 PF08614.11 KPI37888.1 - 1.1e-05 25.8 6.4 1.4e-05 25.5 6.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KPI37888.1 - 0.00056 18.9 4.2 0.00064 18.7 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3450 PF11932.8 KPI37888.1 - 0.00056 19.3 8.2 0.00086 18.7 8.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) FUSC PF04632.12 KPI37888.1 - 0.00065 18.4 0.2 0.00082 18.0 0.2 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family Lebercilin PF15619.6 KPI37888.1 - 0.00066 19.4 8.8 0.00078 19.1 8.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.15 KPI37888.1 - 0.0015 18.6 21.6 0.0056 16.7 13.7 2.4 1 1 2 3 3 3 2 Basic region leucine zipper TPR_MLP1_2 PF07926.12 KPI37888.1 - 0.0023 18.0 8.8 0.0036 17.4 8.8 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 KPI37888.1 - 0.0031 16.2 4.3 0.0033 16.1 4.3 1.0 1 0 0 1 1 1 1 Macoilin family DUF16 PF01519.16 KPI37888.1 - 0.0033 17.9 6.4 0.0047 17.4 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 AAA_13 PF13166.6 KPI37888.1 - 0.0038 16.0 0.9 0.0043 15.8 0.9 1.1 1 0 0 1 1 1 1 AAA domain UPF0242 PF06785.11 KPI37888.1 - 0.0038 17.3 9.3 0.0051 17.0 9.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CREPT PF16566.5 KPI37888.1 - 0.0063 16.7 3.1 0.0063 16.7 3.1 1.9 1 1 1 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour FAM76 PF16046.5 KPI37888.1 - 0.0083 15.5 2.8 0.01 15.2 2.8 1.1 1 0 0 1 1 1 1 FAM76 protein KfrA_N PF11740.8 KPI37888.1 - 0.0086 16.8 2.4 0.012 16.2 2.4 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term bZIP_Maf PF03131.17 KPI37888.1 - 0.009 16.5 17.4 0.015 15.8 17.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor SHE3 PF17078.5 KPI37888.1 - 0.0092 15.7 7.2 0.013 15.2 7.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF4175 PF13779.6 KPI37888.1 - 0.0097 13.9 7.8 0.011 13.7 7.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DivIC PF04977.15 KPI37888.1 - 0.014 15.1 5.3 0.014 15.1 5.3 2.3 1 1 1 2 2 2 0 Septum formation initiator Exonuc_VII_L PF02601.15 KPI37888.1 - 0.018 14.6 4.9 0.02 14.5 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 KPI37888.1 - 0.018 14.3 10.7 0.024 14.0 10.7 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 KPI37888.1 - 0.021 15.2 12.8 0.029 14.7 12.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) VPS38 PF17649.1 KPI37888.1 - 0.029 13.3 3.5 0.036 12.9 3.5 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 FapA PF03961.13 KPI37888.1 - 0.038 12.6 6.9 0.046 12.3 6.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A WDCP PF15390.6 KPI37888.1 - 0.041 12.3 1.8 0.045 12.1 1.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Prefoldin PF02996.17 KPI37888.1 - 0.042 13.8 6.4 0.49 10.3 0.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 KPI37888.1 - 0.045 14.0 9.3 0.065 13.5 9.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 KPI37888.1 - 0.052 13.7 12.4 0.083 13.1 12.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KPI37888.1 - 0.061 13.4 3.8 0.11 12.5 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 KPI37888.1 - 0.064 12.7 4.0 0.086 12.2 4.0 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF2514 PF10721.9 KPI37888.1 - 0.07 13.2 5.0 0.1 12.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Phage_GPO PF05929.11 KPI37888.1 - 0.07 12.7 2.7 0.098 12.3 2.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MbeD_MobD PF04899.12 KPI37888.1 - 0.072 13.2 9.7 0.16 12.1 9.7 1.7 1 1 0 1 1 1 0 MbeD/MobD like DUF4618 PF15397.6 KPI37888.1 - 0.087 12.2 9.6 0.2 11.1 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) IFT57 PF10498.9 KPI37888.1 - 0.099 11.6 9.7 0.13 11.2 9.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 KPI37888.1 - 0.12 12.8 2.6 0.14 12.7 1.1 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 KPI37888.1 - 0.14 12.5 8.7 0.36 11.1 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) EAP30 PF04157.16 KPI37888.1 - 0.15 11.3 5.5 0.24 10.6 5.5 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family V_ATPase_I PF01496.19 KPI37888.1 - 0.27 9.1 3.1 0.32 8.9 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 KPI37888.1 - 0.27 11.3 7.8 0.28 11.2 5.2 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KPI37888.1 - 0.34 9.9 12.4 0.45 9.6 12.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 KPI37888.1 - 0.4 10.4 7.8 0.51 10.1 7.8 1.1 1 0 0 1 1 1 0 AAA domain Phage_Gp23 PF10669.9 KPI37888.1 - 0.47 10.8 6.5 0.7 10.2 6.5 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Sec34 PF04136.15 KPI37888.1 - 0.5 10.3 6.2 0.57 10.1 4.8 1.7 1 1 1 2 2 2 0 Sec34-like family FlxA PF14282.6 KPI37888.1 - 0.51 10.3 23.0 0.87 9.6 20.6 2.0 1 1 1 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.9 KPI37888.1 - 0.53 10.6 8.0 2.8 8.3 6.9 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 KPI37888.1 - 0.54 10.7 14.9 1.5 9.3 14.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) U1snRNP70_N PF12220.8 KPI37888.1 - 0.62 10.7 8.5 0.18 12.5 5.3 1.7 1 1 1 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2203 PF09969.9 KPI37888.1 - 0.63 10.8 6.9 1.6 9.5 7.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 KPI37888.1 - 0.67 9.1 7.7 0.85 8.8 7.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 KPI37888.1 - 0.78 10.4 13.6 1.3 9.7 12.7 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ApoO PF09769.9 KPI37888.1 - 0.86 9.6 2.8 1.3 9.0 2.5 1.4 1 1 0 1 1 1 0 Apolipoprotein O Prominin PF05478.11 KPI37888.1 - 0.97 7.3 3.7 1.2 7.0 3.7 1.0 1 0 0 1 1 1 0 Prominin CorA PF01544.18 KPI37888.1 - 1.2 8.4 4.2 1.6 8.0 4.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4337 PF14235.6 KPI37888.1 - 1.2 9.2 5.3 1.8 8.7 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AKNA PF12443.8 KPI37888.1 - 1.3 9.7 11.0 0.28 11.9 7.0 2.0 2 0 0 2 2 1 0 AT-hook-containing transcription factor SlyX PF04102.12 KPI37888.1 - 1.8 9.2 10.9 0.82 10.3 8.1 1.8 1 1 1 2 2 1 0 SlyX ABC_tran_CTD PF16326.5 KPI37888.1 - 1.9 8.8 9.6 14 6.1 8.1 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Csm1_N PF18504.1 KPI37888.1 - 2.9 8.3 12.6 0.095 13.1 3.4 2.3 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF4446 PF14584.6 KPI37888.1 - 3.2 7.7 6.9 3.8 7.5 6.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Presenilin PF01080.17 KPI37888.1 - 4.7 5.9 5.8 5.5 5.7 5.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 KPI37888.1 - 5.2 6.3 11.7 12 5.2 11.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SOBP PF15279.6 KPI37888.1 - 5.2 7.6 12.3 8.8 6.8 12.3 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein Zn_clus PF00172.18 KPI37889.1 - 1.2e-09 38.1 10.4 2.3e-09 37.2 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI37889.1 - 6.3e-08 32.0 1.1 1.2e-07 31.1 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Snapin_Pallidin PF14712.6 KPI37889.1 - 0.01 16.2 0.7 0.052 14.0 0.0 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Aminotran_3 PF00202.21 KPI37890.1 - 1.9e-90 303.4 0.0 2.4e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Granulin PF00396.18 KPI37891.1 - 6.5 7.2 19.2 0.43 10.9 3.4 3.6 2 1 1 3 3 3 0 Granulin 60KD_IMP PF02096.20 KPI37892.1 - 5.1e-20 72.0 4.2 7.6e-20 71.5 4.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein NMT1_2 PF13379.6 KPI37893.1 - 0.0027 17.5 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Sulfate_transp PF00916.20 KPI37894.1 - 6.1e-69 232.6 16.6 6.7e-37 127.1 4.1 3.3 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 KPI37894.1 - 5.5e-06 26.0 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain YtpI PF14007.6 KPI37894.1 - 0.26 11.5 4.9 3 8.1 0.1 3.2 3 0 0 3 3 3 0 YtpI-like protein Cys_Met_Meta_PP PF01053.20 KPI37895.1 - 1.1e-55 188.8 0.0 2.5e-55 187.6 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GCP_C_terminal PF04130.13 KPI37897.1 - 6.3e-52 177.0 0.8 1.3e-51 175.9 0.8 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal SKG6 PF08693.10 KPI37897.1 - 0.024 14.0 2.4 0.051 13.0 2.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AIP3 PF03915.13 KPI37898.1 - 6.1e-127 424.1 18.5 3.3e-77 260.3 10.8 3.0 2 1 1 3 3 3 2 Actin interacting protein 3 Syntaxin_2 PF14523.6 KPI37898.1 - 0.24 11.8 0.1 0.24 11.8 0.1 4.0 3 1 1 4 4 4 0 Syntaxin-like protein Prominin PF05478.11 KPI37898.1 - 0.24 9.3 0.8 0.38 8.6 0.8 1.2 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 KPI37898.1 - 2.8 8.0 6.6 9.4 6.3 0.4 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SKG6 PF08693.10 KPI37899.1 - 1.8e-09 36.9 1.9 3.6e-09 35.9 1.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 KPI37899.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A PRCH PF03967.13 KPI37899.1 - 0.094 13.0 0.2 0.44 10.8 0.0 2.3 3 0 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region DUF4381 PF14316.6 KPI37899.1 - 0.19 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) JAB PF01398.21 KPI37900.1 - 3.1e-05 23.9 0.0 0.00015 21.7 0.0 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SDF PF00375.18 KPI37901.1 - 2.2e-85 287.0 33.6 2.6e-85 286.8 33.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FAD_binding_3 PF01494.19 KPI37902.1 - 2.8e-25 89.3 0.0 8.1e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI37902.1 - 9.6e-11 41.9 7.9 2.7e-05 23.9 2.3 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI37902.1 - 2.7e-06 26.8 3.8 0.0017 17.7 1.4 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI37902.1 - 1.1e-05 24.5 2.2 0.002 17.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KPI37902.1 - 4.6e-05 22.7 1.5 8.7e-05 21.8 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI37902.1 - 7.2e-05 22.9 0.7 0.00016 21.8 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI37902.1 - 0.00041 19.8 2.5 0.056 12.7 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPI37902.1 - 0.0018 17.5 0.5 0.0018 17.5 0.5 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KPI37902.1 - 0.0027 17.0 1.5 0.21 10.8 1.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI37902.1 - 0.004 16.3 2.9 0.55 9.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KPI37902.1 - 0.015 14.0 1.5 0.11 11.2 1.7 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KPI37902.1 - 0.085 12.2 3.3 0.15 11.4 3.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI37902.1 - 0.094 13.3 5.5 0.089 13.4 1.1 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI37902.1 - 0.11 11.6 4.3 0.48 9.5 4.3 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KPI37902.1 - 0.14 12.1 2.8 5.6 6.9 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.6 KPI37903.1 - 6.6e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI37903.1 - 8.8e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 KPI37903.1 - 0.00062 19.9 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus PucR PF07905.11 KPI37903.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family SGS PF05002.15 KPI37904.1 - 4.9e-24 84.2 7.9 5.2e-23 81.0 7.9 2.7 1 1 0 1 1 1 1 SGS domain CS PF04969.16 KPI37904.1 - 9.3e-10 39.4 1.0 2.1e-09 38.2 1.0 1.6 1 0 0 1 1 1 1 CS domain GET2 PF08690.10 KPI37904.1 - 7.3 6.2 11.1 0.12 12.1 3.0 1.9 2 0 0 2 2 2 0 GET complex subunit GET2 TRI12 PF06609.13 KPI37905.1 - 2.9e-25 88.7 22.1 2.1e-19 69.4 16.0 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI37905.1 - 2.8e-15 56.1 44.3 8.6e-10 38.1 10.3 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI37905.1 - 5.9e-10 38.6 1.1 5.9e-10 38.6 1.1 4.0 3 1 0 4 4 4 1 Sugar (and other) transporter Yip1 PF04893.17 KPI37906.1 - 4.1e-05 23.4 12.6 0.00025 20.8 0.0 2.3 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 KPI37906.1 - 0.051 13.1 2.8 0.89 9.0 2.8 2.4 1 1 0 1 1 1 0 YIF1 Fungal_trans PF04082.18 KPI37908.1 - 1.7e-12 46.9 0.2 1.2e-05 24.5 0.0 2.7 3 0 0 3 3 3 2 Fungal specific transcription factor domain YdjO PF14169.6 KPI37908.1 - 1.5 8.6 7.7 0.14 11.9 2.7 1.8 2 0 0 2 2 2 0 Cold-inducible protein YdjO Zn_clus PF00172.18 KPI37909.1 - 5.6e-08 32.8 9.8 5.6e-08 32.8 9.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI37909.1 - 9.2e-05 21.4 0.3 0.00023 20.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.7 KPI37910.1 - 0.028 14.3 1.6 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 F-box-like CFEM PF05730.11 KPI37911.1 - 2.9e-05 24.1 8.6 2.9e-05 24.1 8.6 2.3 2 0 0 2 2 2 1 CFEM domain 2-Hacid_dh_C PF02826.19 KPI37912.1 - 8.7e-45 152.2 0.1 1e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPI37912.1 - 3.8e-05 23.9 0.1 4.7e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UbiA PF01040.18 KPI37913.1 - 1.6e-39 135.7 17.3 2e-39 135.4 17.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Aldolase_II PF00596.21 KPI37914.1 - 0.00013 22.0 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LIM PF00412.22 KPI37916.1 - 9.7e-27 93.0 25.4 1.9e-12 47.2 2.2 4.6 5 0 0 5 5 5 3 LIM domain Zn_ribbon_recom PF13408.6 KPI37916.1 - 0.0022 18.5 0.7 0.0022 18.5 0.7 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain DUF2321 PF10083.9 KPI37916.1 - 0.025 14.2 0.7 0.025 14.2 0.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) TP6A_N PF04406.14 KPI37917.1 - 1.5e-18 66.6 0.0 3.5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase CDC50 PF03381.15 KPI37918.1 - 3.1e-93 312.3 0.0 4e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1688 PF07958.11 KPI37919.1 - 6.8e-178 591.7 0.0 8.2e-178 591.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Ring_hydroxyl_A PF00848.19 KPI37920.1 - 8.6e-21 74.9 5.9 3.9e-10 40.1 0.1 2.5 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KPI37920.1 - 8.3e-12 44.9 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Eaf7 PF07904.13 KPI37921.1 - 1.1e-19 70.8 2.2 2.1e-19 69.8 0.0 2.4 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Pep1_7 PF17232.2 KPI37921.1 - 0.12 12.8 1.7 1.3 9.6 0.4 2.5 2 0 0 2 2 2 0 Elicitor peptide 1-7 CDC27 PF09507.10 KPI37921.1 - 0.43 9.9 9.8 0.7 9.2 9.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 KPI37921.1 - 8.7 4.4 12.1 12 3.9 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_23 PF13489.6 KPI37922.1 - 0.0052 16.6 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF3602 PF12223.8 KPI37923.1 - 1.7e-12 47.8 19.9 1.6e-05 25.4 3.9 3.7 1 1 1 3 3 3 3 Protein of unknown function (DUF3602) Sde2_N_Ubi PF13019.6 KPI37923.1 - 0.0022 17.8 1.1 0.0051 16.7 0.2 2.0 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain EthD PF07110.11 KPI37924.1 - 2.5e-09 38.2 0.0 5.3e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 EthD domain VGLL4 PF15245.6 KPI37924.1 - 0.043 13.9 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 WLM PF08325.10 KPI37925.1 - 0.029 14.4 1.3 0.044 13.8 0.1 1.6 1 1 1 2 2 2 0 WLM domain Sina PF03145.16 KPI37926.1 - 0.13 12.2 0.4 0.19 11.7 0.4 1.2 1 0 0 1 1 1 0 Seven in absentia protein family DLH PF01738.18 KPI37927.1 - 1.5e-19 70.5 0.1 7.4e-19 68.2 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KPI37927.1 - 0.035 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RabGAP-TBC PF00566.18 KPI37929.1 - 8.5e-23 81.1 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ACAS_N PF16177.5 KPI37929.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Fungal_trans PF04082.18 KPI37930.1 - 2.8e-13 49.5 0.0 1.2e-12 47.4 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI37930.1 - 5.8e-06 26.3 2.5 1.1e-05 25.4 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_1 PF00126.27 KPI37930.1 - 0.0072 16.3 0.0 0.027 14.4 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Pox_A_type_inc PF04508.12 KPI37930.1 - 0.23 11.4 1.8 0.61 10.0 1.8 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Pam16 PF03656.13 KPI37931.1 - 1.9e-05 24.7 0.0 2.5e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KPI37931.1 - 0.0048 17.0 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KPI37931.1 - 5.3 6.7 5.7 0.39 10.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) His_Phos_2 PF00328.22 KPI37932.1 - 0.0071 15.7 0.0 0.35 10.2 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mgm101p PF06420.12 KPI37933.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 PAP2 PF01569.21 KPI37934.1 - 1.6e-13 50.6 6.4 1.6e-13 50.6 6.4 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KPI37934.1 - 0.075 13.2 0.2 2.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Divergent PAP2 family Glyco_hydro_76 PF03663.14 KPI37936.1 - 2.9e-144 481.1 17.1 3.4e-144 480.9 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 KPI37936.1 - 1.6e-05 23.6 0.4 0.13 10.8 0.0 2.5 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 KPI37936.1 - 0.00017 20.8 10.9 0.12 11.4 5.1 3.0 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Acyl-CoA_dh_1 PF00441.24 KPI37937.1 - 1.4e-36 126.0 0.5 2e-36 125.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI37937.1 - 6.9e-18 64.7 0.2 3.5e-17 62.4 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI37937.1 - 8.5e-13 48.7 0.1 1.4e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI37937.1 - 1.1e-08 35.7 0.0 6.8e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KPI37937.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.16 KPI37938.1 - 2.1e-35 122.3 33.9 2.5e-35 122.0 33.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUF PF00806.19 KPI37940.1 - 2.2e-35 118.3 6.9 1.5e-05 24.4 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat DUF2383 PF09537.10 KPI37940.1 - 0.025 14.9 1.2 0.076 13.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) RraB PF06877.11 KPI37940.1 - 0.086 13.6 0.0 0.62 10.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of ribonuclease activity B BicD PF09730.9 KPI37940.1 - 0.12 10.7 11.5 0.35 9.3 11.5 1.4 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Flavoprotein PF02441.19 KPI37941.1 - 8.4e-47 158.8 0.0 9.9e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein p450 PF00067.22 KPI37942.1 - 1.6e-39 136.0 0.1 3.1e-26 92.2 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.14 KPI37943.1 - 3.6e-35 121.7 7.4 4.5e-35 121.4 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_130 PF04041.13 KPI37943.1 - 0.028 13.4 0.4 0.27 10.1 0.2 2.1 1 1 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase ADH_zinc_N_2 PF13602.6 KPI37944.1 - 0.00057 20.9 0.0 0.00061 20.9 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sin3a_C PF16879.5 KPI37945.1 - 1.3e-61 208.9 8.6 1.3e-61 208.9 8.6 3.4 5 0 0 5 5 5 1 C-terminal domain of Sin3a protein PAH PF02671.21 KPI37945.1 - 5.7e-40 135.2 5.1 8.2e-18 64.3 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KPI37945.1 - 4.2e-38 129.3 0.0 1.2e-37 127.9 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor JAB PF01398.21 KPI37945.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.9 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4604 PF15377.6 KPI37946.1 - 0.046 14.2 9.6 2.3 8.6 4.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) Peroxin-3 PF04882.12 KPI37946.1 - 0.81 8.6 3.5 1.2 8.0 3.5 1.2 1 0 0 1 1 1 0 Peroxin-3 FAD_binding_3 PF01494.19 KPI37948.1 - 9.1e-15 54.7 0.1 2.3e-06 27.1 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain SE PF08491.10 KPI37948.1 - 0.027 13.5 0.1 0.78 8.7 0.0 2.5 2 1 1 3 3 3 0 Squalene epoxidase NAD_binding_8 PF13450.6 KPI37948.1 - 0.11 12.8 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UQ_con PF00179.26 KPI37949.1 - 1.8e-51 173.5 0.0 2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3237 PF11578.8 KPI37950.1 - 3.4e-34 117.9 8.8 8.2e-34 116.6 8.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DUF572 PF04502.13 KPI37951.1 - 1e-67 229.1 18.4 1.2e-67 228.9 18.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 KPI37951.1 - 0.027 14.4 0.6 0.027 14.4 0.6 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) zf-ACC PF17848.1 KPI37951.1 - 0.21 11.7 4.0 0.67 10.1 1.0 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain ALMT PF11744.8 KPI37951.1 - 0.68 8.7 5.0 0.77 8.5 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cupin_8 PF13621.6 KPI37951.1 - 5.1 6.7 8.7 5.4 6.7 7.9 1.4 1 1 0 1 1 1 0 Cupin-like domain Presenilin PF01080.17 KPI37951.1 - 7.6 5.2 7.6 10 4.8 7.6 1.3 1 0 0 1 1 1 0 Presenilin BLM10_mid PF16507.5 KPI37953.1 - 1.4e-201 670.7 0.0 2e-201 670.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KPI37953.1 - 4.1e-27 93.9 0.0 1.8e-26 91.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KPI37953.1 - 3.2e-21 75.4 0.0 7.3e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 KPI37953.1 - 9e-06 25.4 0.0 0.24 10.9 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KPI37953.1 - 0.0014 18.7 0.1 1 9.8 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KPI37953.1 - 0.024 15.1 0.1 3.7 8.2 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 KPI37953.1 - 0.034 14.6 0.1 8.8 6.8 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats Ndc1_Nup PF09531.10 KPI37954.1 - 2.3 6.8 10.9 2.6 6.7 10.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RE_SinI PF09570.10 KPI37955.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 SinI restriction endonuclease Egh16-like PF11327.8 KPI37957.1 - 1.8e-41 142.6 12.4 5.7e-41 140.9 9.1 2.5 2 1 0 2 2 2 1 Egh16-like virulence factor Pkinase PF00069.25 KPI37958.1 - 8.6e-71 238.4 0.0 1.2e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI37958.1 - 2.8e-35 121.8 0.0 1.6e-33 116.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI37958.1 - 0.015 14.7 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KPI37958.1 - 0.031 13.6 1.6 0.07 12.5 1.6 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPI37958.1 - 0.083 11.8 0.1 0.22 10.4 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KPI37958.1 - 0.29 9.8 0.0 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase ADH_zinc_N PF00107.26 KPI37959.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI37959.1 - 8.5e-05 22.4 0.0 0.00033 20.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KPI37959.1 - 0.012 15.1 0.2 0.017 14.6 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KPI37959.1 - 0.029 14.3 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 KPI37959.1 - 0.056 12.7 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MMS1_N PF10433.9 KPI37961.1 - 7.2e-49 166.7 0.0 2.7e-47 161.5 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term FMO-like PF00743.19 KPI37962.1 - 2.5e-19 69.1 1.2 1.6e-14 53.3 0.2 2.7 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI37962.1 - 2.3e-11 43.8 0.0 7.3e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI37962.1 - 2.6e-09 36.7 0.1 4.4e-05 22.8 0.1 3.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI37962.1 - 2.1e-08 33.7 0.0 6.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37962.1 - 1.1e-06 28.2 0.1 0.00013 21.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI37962.1 - 0.024 13.9 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KPI37962.1 - 0.074 13.0 3.4 1.5 8.8 0.0 3.7 3 2 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 KPI37962.1 - 0.1 12.2 1.4 1.1 8.8 1.8 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KPI37963.1 - 3.2e-29 102.0 38.2 3.2e-29 102.0 38.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 KPI37963.1 - 0.02 14.9 0.8 0.26 11.3 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S DAO PF01266.24 KPI37964.1 - 1.4e-26 94.0 0.0 1.7e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI37964.1 - 0.00019 20.7 0.0 0.04 13.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI37964.1 - 0.0083 16.3 0.1 0.021 15.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PPTA PF01239.22 KPI37964.1 - 0.0093 15.7 1.1 0.022 14.5 1.1 1.6 1 0 0 1 1 1 1 Protein prenyltransferase alpha subunit repeat Shikimate_DH PF01488.20 KPI37964.1 - 0.01 15.9 0.0 7.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.27 KPI37965.1 - 2.2e-19 70.3 1.1 5.6e-19 68.9 1.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily WW PF00397.26 KPI37965.1 - 0.00028 20.9 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 WW domain Lactamase_B_2 PF12706.7 KPI37965.1 - 0.00047 19.7 0.1 0.00076 19.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CFEM PF05730.11 KPI37966.1 - 9.8e-09 35.2 6.0 9.8e-09 35.2 6.0 1.8 2 0 0 2 2 2 1 CFEM domain MFS_1 PF07690.16 KPI37967.1 - 1.1e-36 126.5 33.6 1.6e-36 126.0 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI37967.1 - 2.5e-11 42.7 3.8 4.8e-11 41.8 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MMPL PF03176.15 KPI37967.1 - 0.086 11.8 2.9 0.05 12.5 0.6 1.8 2 0 0 2 2 2 0 MMPL family stn_TNFRSF12A PF12191.8 KPI37967.1 - 0.23 11.7 2.3 6.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PAP2_C PF14360.6 KPI37967.1 - 1 10.0 5.7 0.18 12.4 0.5 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Methyltransf_32 PF13679.6 KPI37968.1 - 1.5e-24 86.7 0.0 3.5e-24 85.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KPI37968.1 - 0.074 12.6 0.2 1 8.8 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase TRM13 Methyltransf_31 PF13847.6 KPI37968.1 - 0.18 11.6 0.0 0.47 10.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.6 KPI37969.1 - 4.5e-09 36.6 0.0 9.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI37969.1 - 0.029 14.7 0.0 0.085 13.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Abhydrolase_1 PF00561.20 KPI37970.1 - 6.7e-18 65.3 0.0 1.8e-13 50.8 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI37970.1 - 9.7e-14 52.5 0.0 1.2e-13 52.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI37970.1 - 2.7e-10 39.9 0.0 7.5e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KPI37970.1 - 0.035 13.7 0.0 0.074 12.7 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Abhydro_lipase PF04083.16 KPI37970.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Peptidase_S28 PF05577.12 KPI37970.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KPI37970.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2457 PF10446.9 KPI37972.1 - 1.3 8.0 10.5 1.7 7.7 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Alk_phosphatase PF00245.20 KPI37974.1 - 1.5e-73 248.2 0.0 2.3e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase adh_short_C2 PF13561.6 KPI37975.1 - 2.6e-47 161.4 0.0 3.2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI37975.1 - 4.6e-40 137.2 0.0 5.5e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI37975.1 - 9.9e-12 45.1 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI37975.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI37975.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 KPI37975.1 - 0.089 13.0 0.0 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4149 PF13664.6 KPI37976.1 - 3.8e-23 81.7 1.4 4.7e-23 81.4 0.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) CD47 PF04549.14 KPI37976.1 - 0.088 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 CD47 transmembrane region IBR PF01485.21 KPI37977.1 - 2.4e-20 72.5 36.3 3.6e-15 55.9 3.3 3.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KPI37977.1 - 2.4e-15 56.8 0.0 5.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_11 PF17123.5 KPI37977.1 - 0.00014 21.5 6.7 0.00068 19.3 6.7 2.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KPI37977.1 - 0.0031 17.8 11.0 0.0031 17.8 11.0 4.2 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI37977.1 - 0.0083 16.1 9.2 0.0083 16.1 9.2 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPI37977.1 - 0.0096 15.9 10.6 0.0096 15.9 10.6 3.6 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KPI37978.1 - 1.2e-08 35.2 6.6 1.2e-08 35.2 6.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KPI37978.1 - 7.5e-07 28.8 2.6 1.5e-06 27.9 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KPI37978.1 - 0.00012 22.2 5.4 0.0003 21.0 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI37978.1 - 0.00016 21.6 5.2 0.00036 20.5 5.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KPI37978.1 - 0.0041 17.0 2.7 0.0041 17.0 2.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI37978.1 - 0.0044 16.8 3.1 0.0044 16.8 3.1 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KPI37978.1 - 0.0058 16.8 3.5 0.014 15.5 3.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 KPI37978.1 - 0.018 15.0 4.9 0.03 14.3 4.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 KPI37978.1 - 0.051 13.7 2.6 0.11 12.6 2.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 KPI37978.1 - 1.2 9.0 5.6 2.4 8.1 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Alpha_GJ PF03229.13 KPI37979.1 - 0.27 11.8 2.3 0.53 10.8 0.1 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J zf-C2H2 PF00096.26 KPI37981.1 - 0.0045 17.4 3.5 0.013 15.9 3.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type Fungal_trans PF04082.18 KPI37982.1 - 3.1e-15 55.9 0.0 5.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPN13_C PF16550.5 KPI37982.1 - 1.1 9.5 5.7 0.16 12.2 0.4 2.4 3 0 0 3 3 3 0 UCH-binding domain RraA-like PF03737.15 KPI37983.1 - 3.3e-14 53.3 0.0 6.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Aldolase/RraA Glyco_hydro_17 PF00332.18 KPI37983.1 - 4.2e-13 49.6 0.7 1.3e-12 48.0 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 UQ_con PF00179.26 KPI37984.1 - 1.7e-22 79.6 0.0 2.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RPN5_C PF18098.1 KPI37985.1 - 0.18 11.9 0.1 0.65 10.2 0.0 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Chromo_shadow PF01393.19 KPI37986.1 - 0.0047 17.0 0.1 0.077 13.1 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain TPP_enzyme_N PF02776.18 KPI37987.1 - 3e-25 88.8 0.0 8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI37987.1 - 9.5e-21 74.0 0.0 3.2e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KPI37987.1 - 1.4e-09 37.9 0.0 3.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SOBP PF15279.6 KPI37987.1 - 3.5 8.2 13.3 6 7.4 13.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein ANAPC8 PF04049.13 KPI37988.1 - 3.6e-53 179.4 0.4 1.1e-52 177.8 0.4 1.9 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KPI37988.1 - 3e-20 70.7 5.2 1.3e-05 25.0 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPI37988.1 - 1.3e-19 69.1 6.7 0.00023 20.8 0.0 7.2 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPI37988.1 - 1.6e-18 65.8 13.4 0.0026 18.4 0.1 7.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KPI37988.1 - 4.1e-15 54.6 12.6 0.098 12.8 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KPI37988.1 - 3.1e-12 46.0 0.2 7.3e-07 28.8 0.6 3.9 2 1 1 3 3 3 2 TPR repeat ANAPC3 PF12895.7 KPI37988.1 - 5e-11 42.7 5.2 0.2 11.9 0.1 6.1 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KPI37988.1 - 6.3e-10 39.4 9.8 0.082 13.4 0.1 7.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPI37988.1 - 5.8e-09 36.1 6.1 0.51 10.7 0.2 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI37988.1 - 2.9e-08 34.2 19.6 1.5e-05 25.6 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPI37988.1 - 4.3e-07 30.1 11.5 4.3 8.2 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPI37988.1 - 6e-07 29.4 1.1 8.1 7.1 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KPI37988.1 - 2.1e-06 27.2 1.5 0.0084 15.4 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI37988.1 - 6.1e-05 22.8 7.9 0.098 12.7 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPI37988.1 - 0.00019 21.5 8.3 0.027 14.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KPI37988.1 - 0.0015 18.3 4.4 3 7.8 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KPI37988.1 - 0.019 15.5 1.8 0.019 15.5 1.8 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF3856 PF12968.7 KPI37988.1 - 0.13 12.3 2.0 0.96 9.5 0.1 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) ChAPs PF09295.10 KPI37988.1 - 0.15 11.1 0.1 4.2 6.3 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) CI-B14_5a PF07347.12 KPI37989.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Cu-oxidase_3 PF07732.15 KPI37991.1 - 1.1e-26 93.2 0.9 1.4e-25 89.6 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KPI37991.1 - 2.9e-25 89.2 0.0 1e-24 87.5 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPI37991.1 - 3e-16 59.4 7.2 9.7e-14 51.3 0.7 3.7 2 2 0 2 2 2 2 Multicopper oxidase FAD_binding_3 PF01494.19 KPI37992.1 - 7.5e-11 41.9 0.1 7.5e-06 25.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI37992.1 - 6e-05 23.2 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI37992.1 - 0.00015 21.5 0.1 0.00023 20.8 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI37992.1 - 0.0082 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI37992.1 - 0.0095 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI37992.1 - 0.025 15.1 0.0 0.05 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI37992.1 - 0.062 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI37992.1 - 0.076 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein TPT PF03151.16 KPI37993.1 - 4.7e-42 144.3 4.5 6e-42 144.0 4.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPI37993.1 - 4.7e-06 26.8 15.5 1.2e-05 25.6 7.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KPI37993.1 - 9.4e-05 21.8 1.5 0.00015 21.1 1.5 1.2 1 0 0 1 1 1 1 UAA transporter family 7TMR-DISM_7TM PF07695.11 KPI37993.1 - 0.09 12.7 9.5 0.06 13.2 0.9 2.4 1 1 0 2 2 2 0 7TM diverse intracellular signalling AMP-binding PF00501.28 KPI37994.1 - 4.4e-96 322.0 0.0 5.4e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI37994.1 - 6.8e-12 46.2 0.0 2.2e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain JmjC PF02373.22 KPI37995.1 - 3.7e-08 33.8 0.4 6.5e-07 29.8 0.4 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KPI37995.1 - 1.3e-07 31.8 6.9 1.3e-07 31.8 6.9 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KPI37995.1 - 0.008 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain MOSC PF03473.17 KPI37996.1 - 0.00051 20.1 0.1 0.0024 17.9 0.1 1.9 1 1 0 1 1 1 1 MOSC domain Ribonucleas_3_3 PF14622.6 KPI37997.1 - 4.3e-25 88.3 0.0 7.7e-25 87.5 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KPI37997.1 - 4.4e-06 27.3 0.0 9.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Kelch_1 PF01344.25 KPI37998.1 - 5.9e-33 112.2 2.0 1.2e-08 34.4 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KPI37998.1 - 4.9e-28 96.5 8.9 3.5e-08 33.4 0.2 6.8 1 1 5 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KPI37998.1 - 1.8e-24 85.5 17.1 6.4e-06 26.1 0.1 6.5 5 3 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KPI37998.1 - 1.5e-22 79.4 14.1 8.7e-05 22.7 0.0 6.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KPI37998.1 - 3.5e-19 67.9 7.2 3.4e-05 23.6 0.7 7.0 6 2 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KPI37998.1 - 2.4e-12 46.6 3.5 0.24 11.4 0.0 6.4 6 0 0 6 6 6 5 Kelch motif TPR_1 PF00515.28 KPI37999.1 - 1.4e-08 34.2 0.0 0.1 12.4 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPI37999.1 - 1.8e-08 33.8 0.0 0.026 14.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPI37999.1 - 0.00026 21.2 0.7 0.051 13.9 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.31 KPI37999.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain TPR_11 PF13414.6 KPI37999.1 - 0.04 13.6 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 TPR repeat MIT PF04212.18 KPI37999.1 - 0.041 14.0 0.2 11 6.1 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KPI37999.1 - 0.041 13.9 0.0 5.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPI37999.1 - 0.35 11.5 7.0 8.8 7.1 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI37999.1 - 0.44 11.5 4.3 11 7.2 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SQHop_cyclase_C PF13243.6 KPI38000.1 - 3.9e-52 177.3 4.5 1.5e-47 162.3 2.5 2.6 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KPI38000.1 - 1.2e-38 132.9 6.1 6.2e-33 114.1 1.8 3.4 2 2 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KPI38000.1 - 5.5e-30 102.8 6.2 2.3e-10 40.0 0.0 4.9 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KPI38000.1 - 0.0039 16.2 0.0 0.022 13.8 0.2 2.2 2 0 0 2 2 2 1 A-macroglobulin TED domain Mago-bind PF09282.10 KPI38000.1 - 0.16 11.8 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Mago binding Abhydrolase_3 PF07859.13 KPI38001.1 - 1.5e-26 93.6 0.3 1.5e-25 90.3 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI38001.1 - 8.5e-05 21.6 0.1 0.00052 19.0 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Longin PF13774.6 KPI38001.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain Peptidase_S9 PF00326.21 KPI38001.1 - 0.19 11.2 0.2 0.35 10.3 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GST_N_3 PF13417.6 KPI38002.1 - 4.8e-15 55.7 0.0 1.3e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI38002.1 - 9.3e-13 48.3 0.0 2.3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI38002.1 - 3.1e-06 27.1 0.0 7.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KPI38002.1 - 1.4e-05 25.6 0.0 2.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI38002.1 - 0.001 19.4 0.0 0.013 15.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Trypan_PARP PF05887.11 KPI38002.1 - 0.0022 18.0 1.7 0.0076 16.2 1.7 1.9 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GST_C PF00043.25 KPI38002.1 - 0.0057 16.8 0.0 0.048 13.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI38002.1 - 0.0059 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Arginosuc_synth PF00764.19 KPI38004.1 - 1.6e-147 491.9 0.0 1.8e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Apc15p PF05841.11 KPI38005.1 - 5.9e-10 40.0 0.1 5.9e-10 40.0 0.1 4.0 4 1 1 5 5 5 1 Apc15p protein BLOC1S3 PF15753.5 KPI38005.1 - 0.088 12.9 0.3 0.088 12.9 0.3 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 KOW PF00467.29 KPI38006.1 - 0.0032 17.4 0.3 0.0066 16.4 0.3 1.5 1 0 0 1 1 1 1 KOW motif Pmp3 PF01679.17 KPI38007.1 - 1.4e-20 73.2 6.9 1.7e-20 72.9 6.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.11 KPI38007.1 - 0.42 10.2 2.8 0.66 9.5 2.8 1.4 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE AMP-binding PF00501.28 KPI38008.1 - 2.8e-39 134.9 0.0 4.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPI38008.1 - 0.014 15.3 1.8 0.27 11.2 0.1 3.0 3 0 0 3 3 3 0 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KPI38008.1 - 0.12 13.4 0.0 0.25 12.4 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ERCC3_RAD25_C PF16203.5 KPI38009.1 - 3.5e-115 383.4 1.1 5.9e-115 382.7 1.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KPI38009.1 - 2.5e-34 118.1 0.0 5.2e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI38009.1 - 5.7e-16 59.0 0.0 1.5e-15 57.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI38009.1 - 2.4e-12 47.2 0.2 6.1e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KPI38009.1 - 8.4e-09 34.6 0.0 1.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KPI38009.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KPI38009.1 - 0.00022 20.2 0.1 0.00041 19.3 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Peptidase_S37 PF05576.11 KPI38009.1 - 0.093 11.4 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 GLTP PF08718.11 KPI38010.1 - 8.3e-32 110.5 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Nrap_D6 PF17407.2 KPI38010.1 - 0.024 14.8 0.1 0.033 14.4 0.1 1.2 1 0 0 1 1 1 0 Nrap protein domain 6 EF-hand_1 PF00036.32 KPI38010.1 - 0.12 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 EF hand Nup_retrotrp_bd PF10599.9 KPI38012.1 - 5.2 7.8 6.5 0.73 10.5 0.1 2.7 3 0 0 3 3 3 0 Retro-transposon transporting motif DUF4048 PF13257.6 KPI38013.1 - 1e-28 100.9 28.8 5.5e-27 95.2 28.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4048) Ferric_reduct PF01794.19 KPI38014.1 - 1.3e-15 57.6 13.1 3.7e-15 56.1 13.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPI38014.1 - 1.8e-09 37.6 0.0 4.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPI38014.1 - 0.084 13.0 0.0 0.34 11.0 0.0 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Gemini_mov PF01708.16 KPI38014.1 - 1.4 8.8 7.0 2.3 8.0 0.1 3.3 3 0 0 3 3 3 0 Geminivirus putative movement protein Abhydrolase_6 PF12697.7 KPI38015.1 - 1.5e-10 42.0 0.6 2.6e-09 38.0 0.6 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI38015.1 - 3.2e-10 40.1 0.0 5e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI38015.1 - 0.00012 21.4 0.0 0.00034 20.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KPI38015.1 - 0.011 15.6 0.4 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Serine hydrolase Fungal_trans PF04082.18 KPI38017.1 - 5.5e-05 22.3 0.0 9.6e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI38017.1 - 0.00015 21.9 7.7 0.00026 21.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KPI38018.1 - 8e-09 35.5 0.0 3.6e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI38018.1 - 2.4e-08 33.5 0.0 4.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI38018.1 - 1.6e-07 32.2 0.0 1.9e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI38018.1 - 0.082 12.4 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KPI38018.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Glutaredoxin PF00462.24 KPI38019.1 - 1.2e-10 41.4 0.1 3.3e-09 36.8 0.0 2.9 2 1 0 2 2 2 1 Glutaredoxin PQ-loop PF04193.14 KPI38020.1 - 3.6e-21 74.7 1.2 1.3e-13 50.4 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Transglut_core PF01841.19 KPI38020.1 - 1.1e-12 48.4 0.1 2.5e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KPI38020.1 - 0.00059 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI38020.1 - 0.0028 17.2 0.0 0.0069 16.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI38020.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Fungal_trans PF04082.18 KPI38021.1 - 1.8e-22 79.6 0.2 5.7e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_5 PF00941.21 KPI38021.1 - 0.06 13.1 0.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Fungal_trans PF04082.18 KPI38022.1 - 1.2e-39 135.9 0.6 2.2e-39 135.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI38022.1 - 3.8e-08 33.3 8.0 7.3e-08 32.4 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPI38023.1 - 1.4e-19 70.2 30.7 1.4e-19 70.2 30.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 KPI38023.1 - 0.1 10.8 7.5 0.018 13.3 1.8 2.3 2 0 0 2 2 2 0 BT1 family Glyco_hydro_61 PF03443.14 KPI38024.1 - 2.2e-51 174.7 0.0 3e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAA_hydrolase PF01557.18 KPI38025.1 - 7.4e-53 179.4 0.0 1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 KPI38026.1 - 1.4e-07 31.1 0.0 3.2e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI38026.1 - 0.0027 17.9 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Epimerase PF01370.21 KPI38027.1 - 8.6e-17 61.4 0.1 1.4e-16 60.7 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI38027.1 - 3.5e-10 39.4 0.0 4.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPI38027.1 - 1.5e-09 38.0 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KPI38027.1 - 7.1e-08 32.2 0.0 9.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPI38027.1 - 1.3e-07 31.0 0.1 1.8e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KPI38027.1 - 0.0001 21.8 0.7 0.0026 17.2 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KPI38027.1 - 0.00069 18.9 0.1 0.0035 16.6 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KPI38027.1 - 0.0017 17.9 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KPI38027.1 - 0.018 14.9 1.0 0.11 12.4 1.0 2.0 1 1 0 1 1 1 0 KR domain FAD_binding_3 PF01494.19 KPI38029.1 - 3.7e-07 29.7 0.0 4.2e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI38029.1 - 5.7e-05 22.0 1.4 0.00015 20.6 1.4 1.6 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KPI38029.1 - 0.00015 22.2 1.8 0.059 13.9 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI38029.1 - 0.0007 18.9 2.4 0.002 17.4 2.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI38029.1 - 0.003 16.7 1.4 0.005 15.9 1.4 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KPI38029.1 - 0.0039 16.8 11.1 0.46 10.0 7.4 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI38029.1 - 0.014 15.6 4.5 0.07 13.4 3.9 2.3 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KPI38029.1 - 0.019 13.8 4.7 0.049 12.5 2.1 1.9 1 1 1 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KPI38029.1 - 0.045 12.8 6.8 0.054 12.6 5.6 1.6 1 1 1 2 2 2 0 FAD binding domain Methyltransf_16 PF10294.9 KPI38029.1 - 0.057 13.2 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Pyr_redox_3 PF13738.6 KPI38029.1 - 0.077 12.2 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KPI38029.1 - 0.091 12.6 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tfb2_C PF18307.1 KPI38029.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain GIDA PF01134.22 KPI38029.1 - 0.21 10.6 2.1 0.32 10.0 2.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KPI38029.1 - 0.29 10.4 3.9 0.27 10.5 2.9 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KPI38031.1 - 7.2e-26 90.9 36.5 3.2e-25 88.8 36.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI38031.1 - 1.4e-05 24.6 5.8 1.4e-05 24.6 5.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PNTB PF02233.16 KPI38031.1 - 0.23 10.3 2.9 7.8 5.3 0.8 2.2 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit DcpS PF05652.12 KPI38033.1 - 3.6e-27 95.2 0.0 5.6e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KPI38033.1 - 7.4e-27 94.1 0.2 2.1e-26 92.7 0.2 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding adh_short PF00106.25 KPI38035.1 - 2.6e-22 79.3 0.0 1.2e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38035.1 - 8.1e-14 51.7 0.0 1.4e-12 47.7 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38035.1 - 2.7e-05 24.2 0.1 4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KPI38035.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 KPI38035.1 - 0.21 12.0 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Amidase PF01425.21 KPI38036.1 - 3.4e-105 352.6 0.0 7.9e-105 351.4 0.0 1.5 1 1 0 1 1 1 1 Amidase Ald_Xan_dh_C2 PF02738.18 KPI38037.1 - 3.5e-199 662.8 1.9 4.9e-199 662.4 1.9 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KPI38037.1 - 4.6e-37 127.4 0.0 1.1e-36 126.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KPI38037.1 - 7.4e-33 112.8 0.0 3.8e-32 110.5 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KPI38037.1 - 1.4e-25 89.1 0.0 3.5e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 KPI38037.1 - 3.5e-24 85.3 0.0 1.9e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 KPI38037.1 - 1.3e-06 28.3 0.0 4e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GCV_T_C PF08669.11 KPI38037.1 - 0.072 13.0 0.0 0.33 10.9 0.0 2.1 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Sugar_tr PF00083.24 KPI38038.1 - 1.7e-76 257.9 20.8 2e-76 257.7 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI38038.1 - 4.9e-20 71.8 34.9 1e-18 67.4 15.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI38038.1 - 0.0023 16.4 1.2 0.0023 16.4 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KPI38038.1 - 1 7.6 9.6 0.2 9.9 0.8 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 KPI38039.1 - 5.2e-30 103.1 9.6 3.4e-07 30.8 0.5 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KPI38039.1 - 4e-10 39.0 3.1 0.11 11.1 0.4 5.0 4 1 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KPI38039.1 - 8.9e-06 25.9 0.0 0.14 12.5 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain APG6_N PF17675.1 KPI38039.1 - 0.0048 17.4 3.0 0.009 16.5 3.0 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Vezatin PF12632.7 KPI38039.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Seryl_tRNA_N PF02403.22 KPI38039.1 - 0.071 13.4 2.1 0.16 12.2 2.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.12 KPI38039.1 - 0.13 10.4 2.5 0.2 9.8 2.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 KPI38039.1 - 0.16 12.2 3.6 0.3 11.3 3.6 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RasGAP_C PF03836.15 KPI38039.1 - 0.23 11.6 0.5 0.4 10.8 0.5 1.4 1 0 0 1 1 1 0 RasGAP C-terminus DUF4200 PF13863.6 KPI38039.1 - 3.8 7.9 5.7 7.2 7.0 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ACAS_N PF16177.5 KPI38040.1 - 5.6e-11 42.2 2.8 1.1e-10 41.3 2.8 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Pro_isomerase PF00160.21 KPI38042.1 - 7.2e-47 159.6 0.1 8.3e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD L51_S25_CI-B8 PF05047.16 KPI38043.1 - 2.3e-09 37.0 0.1 3.2e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FAD_binding_3 PF01494.19 KPI38044.1 - 0.012 14.9 0.1 0.024 13.9 0.0 1.5 1 1 1 2 2 2 0 FAD binding domain FlgT_N PF16548.5 KPI38045.1 - 0.099 13.2 2.7 0.25 11.9 2.7 1.7 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain KilA-N PF04383.13 KPI38045.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain HET PF06985.11 KPI38046.1 - 1e-29 103.8 0.1 1.9e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CCDC50_N PF15295.6 KPI38047.1 - 0.058 13.6 0.1 3.3 7.9 0.0 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus DUF1180 PF06679.12 KPI38049.1 - 0.26 11.7 3.3 0.24 11.8 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DNA_ligase_A_M PF01068.21 KPI38050.1 - 1.8e-44 151.9 0.0 4.1e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPI38050.1 - 2e-42 145.5 1.1 4.1e-42 144.4 0.0 2.1 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 KPI38050.1 - 4.2e-17 62.3 0.0 1.3e-11 44.7 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KPI38050.1 - 6.4e-17 62.0 3.6 9.8e-17 61.4 0.0 2.9 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KPI38050.1 - 2.3e-14 54.0 0.0 4.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KPI38050.1 - 8.6e-11 42.1 0.0 3.3e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KPI38050.1 - 8.2e-06 25.8 1.2 1.9e-05 24.7 1.2 1.7 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.19 KPI38050.1 - 0.00028 20.8 0.1 0.049 13.5 0.0 3.5 3 0 0 3 3 3 1 mRNA capping enzyme, catalytic domain LIG3_BRCT PF16759.5 KPI38050.1 - 0.038 14.3 0.0 6.3 7.2 0.0 3.0 2 1 0 2 2 2 0 DNA ligase 3 BRCT domain Adaptin_binding PF10199.9 KPI38050.1 - 0.54 10.9 4.7 5 7.8 3.3 2.7 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SnoaL_4 PF13577.6 KPI38051.1 - 7.3e-17 61.7 0.2 9.5e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 KPI38051.1 - 0.007 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative lumazine-binding GILT PF03227.16 KPI38052.1 - 4.3e-15 55.9 0.1 1.1e-14 54.6 0.1 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF1308 PF07000.11 KPI38053.1 - 1.7e-07 31.3 0.0 6.5e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) zf-C3HC4_4 PF15227.6 KPI38054.1 - 1.3e-07 31.7 14.7 4.3e-07 30.0 14.7 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KPI38054.1 - 2.9e-06 27.0 12.1 2.9e-06 27.0 12.1 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI38054.1 - 4.9e-06 26.5 12.7 1.4e-05 25.0 12.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPI38054.1 - 6.1e-06 26.0 10.1 6.1e-06 26.0 10.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI38054.1 - 3.7e-05 24.0 13.6 3.7e-05 24.0 13.6 3.5 4 0 0 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 KPI38054.1 - 0.0002 21.3 10.9 0.0002 21.3 10.9 3.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPI38054.1 - 0.00067 19.5 14.4 0.00067 19.5 14.4 2.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KPI38054.1 - 0.0034 18.0 22.7 0.026 15.2 7.3 4.1 1 1 3 4 4 4 4 TRAF-type zinc finger DUF737 PF05300.11 KPI38054.1 - 0.0068 16.8 1.6 0.012 16.0 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Prok-RING_4 PF14447.6 KPI38054.1 - 0.02 14.8 12.6 0.057 13.3 10.9 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 DUF2046 PF09755.9 KPI38054.1 - 0.02 14.1 1.4 0.034 13.4 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) HR1 PF02185.16 KPI38054.1 - 0.038 14.1 0.4 0.038 14.1 0.4 2.1 3 0 0 3 3 3 0 Hr1 repeat Tup_N PF08581.10 KPI38054.1 - 0.25 11.7 5.4 0.53 10.6 5.4 1.6 1 0 0 1 1 1 0 Tup N-terminal DASH_Spc34 PF08657.10 KPI38054.1 - 0.3 10.9 3.5 0.48 10.2 3.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 DNA_ligase_ZBD PF03119.16 KPI38054.1 - 3.3 7.8 11.8 0.37 10.8 3.9 3.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain CorA PF01544.18 KPI38055.1 - 0.02 14.3 11.0 0.056 12.7 5.1 2.9 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 KPI38056.1 - 1.2e-111 373.7 13.7 2.3e-111 372.9 13.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI38056.1 - 9.9e-16 57.6 28.2 7.4e-13 48.2 11.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38058.1 - 6.2e-28 97.8 11.9 7e-28 97.7 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TctB PF07331.11 KPI38058.1 - 0.2 11.9 7.8 0.31 11.3 7.8 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Glycos_transf_1 PF00534.20 KPI38059.1 - 2.9e-33 114.8 0.0 8.8e-32 110.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPI38059.1 - 7.5e-18 65.1 0.2 2.2e-17 63.6 0.2 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KPI38059.1 - 7.6e-13 49.1 0.0 2.9e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPI38059.1 - 4.9e-10 40.1 0.2 4.9e-10 40.1 0.2 3.1 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KPI38059.1 - 0.00014 22.2 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4999 PF16390.5 KPI38059.1 - 0.011 15.9 0.2 0.03 14.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function Fungal_trans_2 PF11951.8 KPI38059.1 - 0.018 13.9 0.1 0.034 13.0 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Arrestin_C PF02752.22 KPI38060.1 - 8.5e-13 48.9 0.0 1.6e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Ribosomal_L4 PF00573.22 KPI38061.1 - 1.2e-38 132.7 0.0 1.8e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Glyco_transf_90 PF05686.12 KPI38062.1 - 4e-14 52.3 5.8 3.1e-05 23.0 0.0 4.2 3 1 0 3 3 3 3 Glycosyl transferase family 90 FAD_binding_3 PF01494.19 KPI38063.1 - 2.4e-74 250.7 0.0 3e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPI38063.1 - 4.6e-36 124.4 0.0 8.2e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KPI38063.1 - 0.0002 20.7 0.0 0.013 14.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI38063.1 - 0.00024 20.8 0.2 0.05 13.2 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI38063.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI38063.1 - 0.062 13.9 0.0 0.35 11.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KPI38063.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KPI38063.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KPI38064.1 - 9.2e-37 127.4 0.6 1e-36 127.2 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI38064.1 - 7.3e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KPI38064.1 - 0.00011 21.5 0.1 0.00011 21.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KPI38064.1 - 0.00081 19.6 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI38064.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI38064.1 - 0.052 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_2 PF13639.6 KPI38066.1 - 2.7e-05 24.4 7.5 6.5e-05 23.2 7.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KPI38066.1 - 7e-05 22.8 4.2 0.00013 22.0 4.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KPI38066.1 - 0.0015 18.8 8.0 0.0036 17.5 8.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zf_RING PF16744.5 KPI38066.1 - 0.049 13.8 5.3 0.14 12.3 5.3 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 KPI38066.1 - 0.23 11.7 6.7 0.77 10.0 6.1 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 KPI38066.1 - 0.54 10.3 3.5 1.2 9.2 3.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KPI38066.1 - 1 9.3 6.9 2.3 8.2 6.9 1.6 1 0 0 1 1 1 0 PHD-finger CDC45 PF02724.14 KPI38066.1 - 1.1 7.5 16.2 1.7 6.8 16.2 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-RING_4 PF14570.6 KPI38066.1 - 1.4 8.8 7.7 8.6 6.2 2.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SDA1 PF05285.12 KPI38066.1 - 4.3 6.7 28.8 6.5 6.1 28.8 1.2 1 0 0 1 1 1 0 SDA1 adh_short_C2 PF13561.6 KPI38067.1 - 2.6e-50 171.2 1.0 3.3e-35 121.8 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38067.1 - 3.5e-42 144.1 2.0 1.6e-41 141.9 2.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI38067.1 - 4.9e-07 29.8 1.1 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF4185 PF13810.6 KPI38068.1 - 8.9e-16 58.0 5.8 1.8e-14 53.7 3.7 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4185) Retinal PF15449.6 KPI38069.1 - 0.55 8.0 13.9 0.6 7.8 13.9 1.0 1 0 0 1 1 1 0 Retinal protein AMP-binding PF00501.28 KPI38070.1 - 7.3e-24 84.1 0.2 2.4e-21 75.8 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KPI38070.1 - 0.0011 19.9 0.1 0.0024 18.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_deac_1 PF01522.21 KPI38071.1 - 7.1e-17 61.5 0.0 1.3e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPI38071.1 - 0.00019 21.1 0.1 0.00069 19.3 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KPI38071.1 - 0.091 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Peroxidase_2 PF01328.17 KPI38071.1 - 0.17 12.4 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Peroxidase, family 2 DUF4629 PF15442.6 KPI38072.1 - 0.0081 16.4 3.2 0.01 16.1 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4629) DUF3807 PF12720.7 KPI38072.1 - 0.67 10.2 6.1 4.4 7.6 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PPL5 PF18168.1 KPI38072.1 - 1.6 7.9 4.6 2.1 7.6 4.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 HET PF06985.11 KPI38073.1 - 8.4e-17 61.9 0.1 1e-16 61.6 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glutaredoxin PF00462.24 KPI38074.1 - 2e-17 63.2 0.1 3e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KPI38074.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI38074.1 - 0.018 15.5 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 KPI38074.1 - 0.035 14.5 0.5 0.083 13.4 0.5 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 KPI38074.1 - 0.051 13.3 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 KPI38074.1 - 0.073 12.8 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 KPI38074.1 - 0.091 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF836 PF05768.14 KPI38074.1 - 0.097 13.1 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Aldo_ket_red PF00248.21 KPI38075.1 - 7.2e-70 235.5 0.0 8.7e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Apc13p PF05839.11 KPI38076.1 - 2e-13 50.4 0.0 1.7e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Apc13p protein Aldedh PF00171.22 KPI38077.1 - 3e-112 375.5 0.0 5.5e-58 196.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Mg_chelatase PF01078.21 KPI38077.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SnoaL_4 PF13577.6 KPI38078.1 - 4.2e-14 52.8 1.0 5.5e-14 52.4 1.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain p450 PF00067.22 KPI38079.1 - 1.1e-70 238.7 0.0 1.2e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA_bind PF01588.20 KPI38080.1 - 1.5e-18 66.7 0.1 9.2e-18 64.2 0.1 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain TRAM_LAG1_CLN8 PF03798.16 KPI38081.1 - 4.8e-38 130.9 21.1 8.5e-38 130.1 21.1 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KPI38081.1 - 2.1e-20 72.1 0.1 2.1e-20 72.1 0.1 2.4 2 1 0 2 2 2 1 TRAM1-like protein Phage_Gp23 PF10669.9 KPI38081.1 - 0.1 13.0 0.4 0.23 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) MYCBPAP PF14646.6 KPI38081.1 - 0.21 10.5 0.2 0.31 9.9 0.2 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family Surfac_D-trimer PF09006.11 KPI38082.1 - 0.51 10.3 2.2 17 5.4 0.1 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation adh_short_C2 PF13561.6 KPI38083.1 - 9.9e-48 162.7 3.9 1.1e-47 162.6 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38083.1 - 1.1e-46 158.8 3.1 1.2e-46 158.6 3.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI38083.1 - 1.4e-12 47.9 1.2 1.8e-12 47.5 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI38083.1 - 0.00043 19.8 0.9 0.00081 18.9 0.2 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI38083.1 - 0.0022 17.2 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 KPI38083.1 - 0.019 14.3 0.2 0.22 10.9 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KPI38083.1 - 0.051 13.5 0.9 0.071 13.0 0.9 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KPI38083.1 - 0.063 13.1 0.2 0.088 12.7 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 KPI38083.1 - 0.079 12.5 0.9 0.12 11.9 0.9 1.5 1 1 0 1 1 1 0 NmrA-like family DUF4939 PF16297.5 KPI38084.1 - 0.0026 17.6 0.6 0.0092 15.9 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4939) Dynamin_N PF00350.23 KPI38085.1 - 3.2e-18 66.4 0.7 9.2e-18 64.9 0.0 2.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KPI38085.1 - 4e-10 39.8 0.0 5e-09 36.2 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI38085.1 - 3.3e-07 30.0 1.1 7.4e-06 25.6 0.4 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KPI38085.1 - 0.0062 17.1 0.0 0.025 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KPI38085.1 - 0.064 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Epimerase PF01370.21 KPI38087.1 - 7.5e-08 32.1 0.0 5.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI38087.1 - 2.8e-07 30.6 0.0 7.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPI38087.1 - 7.9e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KPI38087.1 - 0.00027 21.3 0.1 0.0015 19.0 0.0 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPI38087.1 - 0.0011 19.2 0.1 0.0022 18.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KPI38087.1 - 0.0028 16.9 0.1 0.0055 15.9 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPI38087.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1521 PF07481.11 KPI38087.1 - 0.048 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) 3Beta_HSD PF01073.19 KPI38087.1 - 0.085 11.8 0.1 0.26 10.3 0.1 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.19 KPI38088.1 - 3.8e-82 276.3 0.0 5e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPI38088.1 - 8e-25 87.8 0.0 2.5e-24 86.2 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KPI38088.1 - 2.6e-05 23.6 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI38088.1 - 0.00026 20.2 0.1 0.00051 19.2 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KPI38088.1 - 0.0008 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KPI38088.1 - 0.0013 19.2 0.0 0.0043 17.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI38088.1 - 0.0052 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KPI38088.1 - 0.007 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI38088.1 - 0.0073 15.9 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI38088.1 - 0.0091 15.1 0.1 0.018 14.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KPI38088.1 - 0.086 13.1 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain XdhC_C PF13478.6 KPI38088.1 - 0.12 12.9 0.0 0.4 11.2 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain PALP PF00291.25 KPI38088.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_oxidored PF12831.7 KPI38088.1 - 0.15 11.4 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.22 KPI38089.1 - 1.3e-51 175.8 0.0 1.6e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3500 PF12006.8 KPI38090.1 - 9.4e-100 333.9 0.0 1.2e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) tRNA_int_end_N2 PF12928.7 KPI38092.1 - 3.7e-16 59.1 0.0 8.6e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KPI38092.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain adh_short_C2 PF13561.6 KPI38093.1 - 1.3e-26 93.6 2.0 2.7e-10 40.2 0.0 3.1 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38093.1 - 2.5e-21 76.0 3.2 6.6e-13 48.6 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI38093.1 - 1.3e-15 57.8 0.6 8.6e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KPI38093.1 - 2.3e-05 24.0 0.1 0.0028 17.2 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI38093.1 - 0.03 14.2 0.2 0.2 11.5 0.2 2.5 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPI38093.1 - 0.042 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain zf-C2H2_6 PF13912.6 KPI38093.1 - 0.056 13.5 1.3 0.081 13.0 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KPI38093.1 - 0.062 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Polysacc_synt_2 PF02719.15 KPI38093.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPI38093.1 - 0.14 11.5 0.1 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Abhydrolase_6 PF12697.7 KPI38094.1 - 1e-06 29.6 4.1 1e-06 29.6 4.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI38094.1 - 7.4e-05 22.5 0.1 0.00011 21.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 KPI38094.1 - 8.5e-05 21.5 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KPI38094.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPI38094.1 - 0.00037 19.8 0.0 0.0017 17.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPI38094.1 - 0.019 14.8 0.1 0.077 12.8 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KPI38094.1 - 0.039 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain AXE1 PF05448.12 KPI38094.1 - 0.094 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 KPI38094.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MFS_1 PF07690.16 KPI38095.1 - 1.3e-30 106.6 29.8 1.5e-30 106.3 29.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPI38095.1 - 0.022 14.6 0.1 0.022 14.6 0.1 2.4 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cu_amine_oxid PF01179.20 KPI38096.1 - 5.4e-119 397.7 1.8 6.6e-119 397.5 1.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KPI38096.1 - 6.9e-09 35.3 0.1 1.7e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KPI38096.1 - 0.0018 18.4 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MiAMP1 PF09117.10 KPI38097.1 - 0.093 13.0 1.4 1.1 9.5 0.1 2.3 1 1 1 2 2 2 0 MiAMP1 BCIP PF13862.6 KPI38098.1 - 6.3e-66 222.1 0.0 8e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein adh_short PF00106.25 KPI38099.1 - 2.3e-25 89.2 0.0 4.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38099.1 - 2.3e-17 63.4 0.0 5.4e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38099.1 - 0.09 12.7 0.3 9 6.2 0.0 2.4 2 0 0 2 2 2 0 KR domain Amidase PF01425.21 KPI38100.1 - 1.6e-99 333.9 0.0 2e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Amidase SH3_15 PF18346.1 KPI38100.1 - 0.086 13.2 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain Cpn60_TCP1 PF00118.24 KPI38101.1 - 6.4e-152 506.6 16.9 7.3e-152 506.4 16.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4112 PF13430.6 KPI38102.1 - 1.1e-31 109.2 0.5 1.7e-31 108.6 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 KPI38102.1 - 0.057 13.5 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein SET PF00856.28 KPI38103.1 - 2.7e-12 47.4 0.0 1e-11 45.5 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_8 PF13181.6 KPI38103.1 - 0.0059 16.7 0.2 0.023 14.9 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat SWM_repeat PF13753.6 KPI38103.1 - 0.22 11.7 0.0 0.22 11.7 0.0 2.2 3 0 0 3 3 3 0 Putative flagellar system-associated repeat Het-C PF07217.11 KPI38104.1 - 1.1e-229 763.7 8.5 1.6e-213 710.4 3.9 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C SOG2 PF10428.9 KPI38104.1 - 0.73 9.0 7.3 1.2 8.2 7.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 KPI38104.1 - 8.7 5.1 10.4 15 4.3 10.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_127 PF07944.12 KPI38106.1 - 3.7e-13 48.8 0.0 8.5e-13 47.6 0.0 1.5 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 GFA PF04828.14 KPI38107.1 - 7.9e-13 48.6 14.2 1.2e-06 28.8 0.4 3.5 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NinF PF05810.12 KPI38107.1 - 0.084 12.8 0.8 13 5.7 0.0 2.7 2 0 0 2 2 2 0 NinF protein Sugar_tr PF00083.24 KPI38109.1 - 5.4e-85 285.9 32.2 6.9e-85 285.6 32.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI38109.1 - 1.2e-20 73.8 44.3 1.2e-20 73.8 44.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily U1snRNP70_N PF12220.8 KPI38110.1 - 5.3e-23 81.5 3.2 8.8e-23 80.8 3.2 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KPI38110.1 - 1.4e-17 63.2 0.0 4.4e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI38110.1 - 5e-05 23.3 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif GP3_package PF16677.5 KPI38110.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA-packaging protein gp3 Asp PF00026.23 KPI38111.1 - 2.7e-55 188.0 1.2 3.2e-55 187.8 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI38111.1 - 3.5e-06 27.4 0.4 0.11 12.7 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI38111.1 - 0.0001 22.9 1.6 0.37 11.5 0.9 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI38111.1 - 0.023 15.2 0.5 3.6 8.2 0.1 3.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Kelch_4 PF13418.6 KPI38111.1 - 0.19 11.8 1.3 6.4 6.9 0.2 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Acetyltransf_1 PF00583.25 KPI38112.1 - 6.2e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 KPI38112.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_10 PF13673.7 KPI38112.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI38112.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KPI38112.1 - 0.1 12.6 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 KPI38112.1 - 0.13 12.4 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KPI38113.1 - 4.5e-36 124.7 8.6 5e-36 124.5 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI38113.1 - 4.6e-11 42.2 22.8 6.1e-11 41.8 22.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NMO PF03060.15 KPI38114.1 - 5.7e-48 164.0 0.4 3.4e-47 161.4 0.4 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI38114.1 - 2e-10 40.2 0.0 5.6e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPI38114.1 - 6.7e-06 25.4 0.1 9.5e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 KPI38114.1 - 0.0014 17.8 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KPI38114.1 - 0.019 14.4 0.1 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein SfLAP PF11139.8 KPI38114.1 - 0.25 10.8 1.1 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein FeS PF04060.13 KPI38114.1 - 0.48 10.1 2.2 20 4.9 0.1 3.4 3 0 0 3 3 3 0 Putative Fe-S cluster Pyr_redox_2 PF07992.14 KPI38115.1 - 4.5e-44 150.8 0.0 5.8e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI38115.1 - 2.4e-11 44.0 0.0 1.4e-09 38.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI38115.1 - 0.0047 16.2 0.0 3.7 6.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPI38115.1 - 0.027 14.9 0.5 0.55 10.7 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding TetR_C_19 PF17924.1 KPI38115.1 - 0.063 13.9 0.1 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain COX14 PF14880.6 KPI38115.1 - 0.17 11.7 0.1 0.44 10.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF4452 PF14618.6 KPI38117.1 - 5.3e-62 208.7 10.2 6.9e-62 208.3 10.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) RP-C_C PF11800.8 KPI38117.1 - 0.083 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Skp1_POZ PF03931.15 KPI38119.1 - 2.9e-10 40.1 0.0 5.8e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 KPI38119.1 - 0.053 13.8 0.0 0.065 13.5 0.0 1.1 1 0 0 1 1 1 0 BTB/POZ domain Glyco_hydro_61 PF03443.14 KPI38120.1 - 2.6e-63 213.7 0.1 3.7e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.28 KPI38121.1 - 4.2e-95 319.6 0.0 4.6e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI38121.1 - 2e-07 31.1 0.5 1.1e-06 28.6 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 KPI38125.1 - 0.092 12.9 5.4 0.15 12.2 5.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 KPI38126.1 - 1.9e-38 132.3 0.2 2.4e-38 131.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI38126.1 - 1.5e-20 74.0 0.1 1.9e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KPI38126.1 - 0.021 14.8 0.0 0.22 11.5 0.0 2.3 3 0 0 3 3 3 0 Peptidase family S49 Lung_7-TM_R PF06814.13 KPI38127.1 - 1.2e-64 218.4 14.7 1.4e-64 218.2 14.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Acyl-CoA_ox_N PF14749.6 KPI38128.1 - 7.9e-19 68.4 1.6 1.6e-18 67.5 1.6 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPI38128.1 - 3.8e-09 36.6 0.0 1.2e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KPI38128.1 - 7.6e-06 25.6 0.2 1.9e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 KPI38128.1 - 0.0027 17.9 0.2 0.0072 16.5 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GPAT_N PF14829.6 KPI38128.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Aldedh PF00171.22 KPI38129.1 - 4.7e-123 411.1 0.0 5.2e-123 411.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPI38129.1 - 0.0031 16.6 0.2 0.015 14.4 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.17 KPI38129.1 - 0.089 12.6 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 ATP synthase subunit D Sec7 PF01369.20 KPI38130.1 - 4.7e-64 215.4 0.0 7.6e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KPI38130.1 - 1.1e-18 67.7 0.0 6.7e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ParA PF10609.9 KPI38131.1 - 6.4e-97 323.8 0.0 7.4e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KPI38131.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KPI38131.1 - 1.7e-05 24.8 0.0 6e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KPI38131.1 - 3.3e-05 23.2 0.8 0.00061 19.1 0.3 2.4 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_30 PF13604.6 KPI38131.1 - 0.0057 16.4 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KPI38131.1 - 0.033 14.0 0.0 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KPI38131.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 KPI38131.1 - 0.055 12.9 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 KPI38131.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 KPI38131.1 - 0.094 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 KPI38131.1 - 0.11 11.7 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ T2SSE PF00437.20 KPI38131.1 - 0.14 11.2 0.1 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 KPI38131.1 - 0.22 12.1 0.1 0.4 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain TIP120 PF08623.10 KPI38132.1 - 4.1e-52 176.3 0.0 8.8e-50 168.8 0.0 4.0 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KPI38132.1 - 3.1e-16 59.5 13.5 0.0011 19.4 0.0 8.5 5 3 1 7 7 7 4 HEAT repeats HEAT PF02985.22 KPI38132.1 - 1.3e-10 40.6 14.8 0.02 15.1 0.0 11.4 12 0 0 12 12 12 1 HEAT repeat DRIM PF07539.12 KPI38132.1 - 1.3e-08 33.7 3.4 0.0067 14.8 0.0 4.9 3 1 1 5 5 5 2 Down-regulated in metastasis HEAT_EZ PF13513.6 KPI38132.1 - 0.00078 19.9 20.2 0.88 10.2 0.0 9.2 8 2 1 9 9 9 2 HEAT-like repeat RTP1_C1 PF10363.9 KPI38132.1 - 0.0021 18.2 5.3 7.8 6.7 0.0 6.0 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KPI38132.1 - 0.0053 16.8 0.8 2.1 8.3 0.0 4.9 5 2 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KPI38132.1 - 0.019 13.6 9.0 1 7.8 0.2 5.0 4 2 0 4 4 4 0 Adaptin N terminal region Arm PF00514.23 KPI38132.1 - 0.52 10.4 7.3 11 6.3 0.0 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KPI38132.1 - 2.4 7.2 24.8 0.56 9.3 1.3 6.5 6 2 0 7 7 7 0 RNAPII transcription regulator C-terminal Sigma70_ner PF04546.13 KPI38132.1 - 5.5 6.8 6.2 12 5.8 3.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region ABC_trans_N PF14510.6 KPI38133.1 - 0.071 13.7 0.7 2.6 8.7 0.0 2.7 3 0 0 3 3 3 0 ABC-transporter N-terminal Pyr_redox_3 PF13738.6 KPI38134.1 - 7.7e-08 31.9 0.0 2.7e-05 23.6 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI38134.1 - 9.8e-08 31.6 0.0 0.017 14.3 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI38134.1 - 2.5e-07 29.5 0.0 2.3e-06 26.3 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI38134.1 - 1.8e-05 24.1 0.0 0.00051 19.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KPI38134.1 - 0.00025 21.1 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KPI38134.1 - 0.0012 19.1 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI38134.1 - 0.05 13.2 0.0 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KPI38134.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain muHD PF10291.9 KPI38134.1 - 0.14 11.6 0.0 0.43 10.0 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Atg14 PF10186.9 KPI38135.1 - 8.9e-14 51.3 7.4 1.1e-09 37.9 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KPI38135.1 - 2.6e-12 46.4 0.0 3.4e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting 38 AAA_13 PF13166.6 KPI38135.1 - 0.01 14.5 1.3 0.015 14.0 1.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4763 PF15960.5 KPI38135.1 - 0.067 12.5 3.5 0.11 11.8 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 KPI38135.1 - 0.16 10.8 5.5 0.26 10.1 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5101 PF17031.5 KPI38135.1 - 0.8 9.8 2.2 5.7 7.1 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) Cnn_1N PF07989.11 KPI38135.1 - 1.4 9.1 5.9 0.76 10.0 0.5 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Med9 PF07544.13 KPI38135.1 - 1.6 8.9 6.1 5.1 7.3 6.1 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NYD-SP28_assoc PF14775.6 KPI38135.1 - 2.2 8.5 4.5 21 5.3 0.6 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Snapin_Pallidin PF14712.6 KPI38135.1 - 2.9 8.4 7.1 5.6 7.5 7.1 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Nnf1 PF03980.14 KPI38135.1 - 2.9 8.3 8.3 5.7 7.4 8.3 1.5 1 0 0 1 1 1 0 Nnf1 Pkinase PF00069.25 KPI38136.1 - 6.8e-15 55.1 0.0 2.2e-14 53.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI38136.1 - 1.5e-06 27.7 0.0 8.4e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI38136.1 - 0.00012 22.1 0.0 0.066 13.1 0.0 3.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family SIN1 PF05422.12 KPI38136.1 - 0.087 13.4 0.8 0.26 11.8 0.8 1.8 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Fungal_trans PF04082.18 KPI38137.1 - 9.5e-41 139.6 5.6 1.9e-40 138.6 5.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPI38137.1 - 4.5e-10 39.4 11.4 8.1e-06 26.0 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI38137.1 - 2.6e-05 24.7 9.9 0.027 15.3 1.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KPI38137.1 - 0.007 17.0 3.3 0.02 15.5 3.3 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain DM PF00751.18 KPI38137.1 - 2.3 8.2 4.6 4.2 7.4 0.6 2.3 2 0 0 2 2 2 0 DM DNA binding domain zf-met PF12874.7 KPI38137.1 - 9.7 6.7 6.2 9.6 6.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ThiF PF00899.21 KPI38138.1 - 5.8e-74 248.5 0.1 8.1e-74 248.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KPI38138.1 - 2.6e-18 66.4 0.9 1e-17 64.5 0.9 2.1 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KPI38138.1 - 1.5e-10 41.4 0.9 3.5e-07 30.4 0.2 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KPI38138.1 - 0.0014 19.0 0.0 0.0056 17.1 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KPI38138.1 - 0.0045 17.5 0.6 1.7 9.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF2443 PF10398.9 KPI38138.1 - 0.021 14.9 0.0 0.083 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Shikimate_DH PF01488.20 KPI38138.1 - 0.025 14.6 0.1 0.068 13.2 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KPI38139.1 - 2.3e-19 70.0 0.0 4.4e-19 69.1 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPI38139.1 - 3.5e-06 26.8 0.0 5.3e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KPI38139.1 - 0.0002 20.9 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPI38139.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L27A PF00828.19 KPI38140.1 - 1.5e-08 35.4 0.3 2.8e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Oxidored_FMN PF00724.20 KPI38141.1 - 4.4e-91 305.7 0.0 5.5e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KPI38141.1 - 0.047 13.1 0.1 4.5 6.6 0.0 2.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel DLH PF01738.18 KPI38143.1 - 1.3e-28 100.1 0.0 1.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LOR PF04525.12 KPI38144.1 - 7.3e-17 61.6 0.0 8.2e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related ALG3 PF05208.13 KPI38145.1 - 5.2e-126 420.9 9.0 6e-126 420.7 9.0 1.0 1 0 0 1 1 1 1 ALG3 protein Amidohydro_1 PF01979.20 KPI38146.1 - 1.2e-41 143.2 0.0 1.4e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI38146.1 - 2.3e-16 60.3 0.1 1.1e-11 44.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Kelch_4 PF13418.6 KPI38147.1 - 2.7e-23 81.7 0.6 9.9e-13 47.9 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KPI38147.1 - 2e-20 72.6 0.5 0.00052 20.2 0.1 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KPI38147.1 - 1.2e-07 31.7 0.4 0.15 12.4 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KPI38147.1 - 0.00011 21.7 0.0 2.8 7.6 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 KPI38147.1 - 0.00014 21.7 0.0 0.5 10.4 0.0 3.5 4 0 0 4 4 4 2 Kelch motif DIOX_N PF14226.6 KPI38148.1 - 1.3e-30 106.6 0.1 2.5e-30 105.6 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI38148.1 - 3.9e-23 81.9 0.1 1.4e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.22 KPI38149.1 - 9.1e-21 74.9 0.0 1.5e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI38149.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain THF_DHG_CYH PF00763.23 KPI38149.1 - 0.081 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF5481 PF17578.2 KPI38150.1 - 0.12 12.8 1.7 1.5 9.3 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5481) ERCC4 PF02732.15 KPI38151.1 - 2.2e-14 54.0 0.0 5.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Ca_bind_SSO6904 PF18249.1 KPI38151.1 - 0.033 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Calcium binding protein SSO6904 Borrelia_P83 PF05262.11 KPI38151.1 - 0.061 11.8 11.8 0.1 11.1 11.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec62 PF03839.16 KPI38151.1 - 6 6.3 8.7 14 5.1 8.7 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Ureide_permease PF07168.11 KPI38151.1 - 7.1 5.3 5.0 11 4.6 5.0 1.2 1 0 0 1 1 1 0 Ureide permease Suf PF05843.14 KPI38152.1 - 2.3e-12 47.5 5.9 0.039 13.9 0.0 6.1 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KPI38152.1 - 2.7e-09 37.1 24.4 1.6 9.7 0.0 11.4 8 2 4 12 12 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPI38152.1 - 4.7e-06 27.0 3.0 3.5 8.2 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KPI38152.1 - 0.0021 18.0 8.4 9.2 6.3 0.0 6.4 6 3 1 8 8 8 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 KPI38152.1 - 0.044 14.2 4.5 9.9 6.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KPI38152.1 - 0.22 10.6 14.2 0.33 10.0 0.4 5.9 3 2 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 KPI38152.1 - 0.35 11.1 12.4 8.1 6.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPI38152.1 - 0.71 10.0 4.2 30 4.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI38152.1 - 2.9 8.8 9.6 0.75 10.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI38152.1 - 7.9 7.4 10.4 72 4.3 0.1 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 KPI38153.1 - 1.7e-17 64.0 7.2 3.7e-07 30.2 0.0 3.9 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KPI38153.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 KPI38153.1 - 0.00042 19.7 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 KPI38153.1 - 0.0018 17.6 0.0 0.33 10.2 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KPI38153.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KPI38153.1 - 0.056 13.1 0.0 0.28 10.8 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KPI38154.1 - 2.5e-35 122.0 2.0 4.2e-35 121.3 2.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain UME PF08064.13 KPI38154.1 - 0.096 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 UME (NUC010) domain Sec2p PF06428.11 KPI38155.1 - 7.6e-11 41.8 6.8 7.6e-11 41.8 6.8 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p MbeB_N PF04837.12 KPI38155.1 - 0.034 14.4 0.9 0.12 12.7 0.9 2.0 1 0 0 1 1 1 0 MbeB-like, N-term conserved region DUF4763 PF15960.5 KPI38155.1 - 0.048 13.0 9.5 0.14 11.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) LegC3_N PF18654.1 KPI38155.1 - 0.18 11.0 5.4 0.56 9.4 2.3 2.2 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Jnk-SapK_ap_N PF09744.9 KPI38155.1 - 0.2 11.9 19.4 1.2 9.3 1.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4795 PF16043.5 KPI38155.1 - 0.24 11.0 4.0 1.9 8.0 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) TFIIA PF03153.13 KPI38155.1 - 0.29 11.1 11.5 0.33 10.9 11.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4140 PF13600.6 KPI38155.1 - 0.41 11.1 12.0 0.41 11.1 0.0 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 KPI38155.1 - 0.45 9.3 14.7 0.25 10.2 6.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein ECM11 PF15463.6 KPI38155.1 - 0.49 11.0 6.4 0.096 13.3 2.4 1.8 2 0 0 2 2 2 0 Extracellular mutant protein 11 DASH_Spc19 PF08287.11 KPI38155.1 - 0.98 9.3 14.8 0.41 10.5 1.1 2.3 2 0 0 2 2 2 0 Spc19 YlqD PF11068.8 KPI38155.1 - 1.2 9.5 13.9 1.7 9.0 3.4 2.1 2 0 0 2 2 2 0 YlqD protein DUF4407 PF14362.6 KPI38155.1 - 2.1 7.6 12.3 0.82 9.0 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KPI38155.1 - 3.3 8.2 15.8 1.2 9.6 0.2 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region TACC_C PF05010.14 KPI38155.1 - 4.2 7.1 10.1 2.6 7.8 0.4 2.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal XhlA PF10779.9 KPI38155.1 - 7.2 6.9 6.1 4.1 7.7 0.3 2.8 3 0 0 3 3 3 0 Haemolysin XhlA SPX PF03105.19 KPI38155.1 - 7.7 6.3 8.8 11 5.8 8.8 1.2 1 0 0 1 1 1 0 SPX domain HAUS6_N PF14661.6 KPI38155.1 - 8.1 5.9 10.7 7.3 6.1 1.9 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Aldo_ket_red PF00248.21 KPI38156.1 - 2.3e-63 214.1 0.0 2.6e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 KPI38157.1 - 2.8e-56 190.9 0.0 3.9e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI38157.1 - 1.4e-12 48.4 0.0 2.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 KPI38158.1 - 3.6e-55 187.1 0.0 4.2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38158.1 - 7.6e-38 129.9 0.1 9.8e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI38158.1 - 3.1e-10 40.3 1.4 6.9e-10 39.1 1.4 1.5 1 1 0 1 1 1 1 KR domain GFA PF04828.14 KPI38159.1 - 3.8e-05 24.0 0.0 8.3e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KPI38159.1 - 0.18 11.7 0.1 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 Nudix N-terminal MAJIN PF15077.6 KPI38159.1 - 0.42 10.4 3.7 9.5 5.9 1.3 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein DUF3446 PF11928.8 KPI38159.1 - 9 6.7 10.6 2.5 8.4 5.8 2.3 3 0 0 3 3 3 0 Early growth response N-terminal domain FAD_binding_3 PF01494.19 KPI38160.1 - 6.8e-07 28.9 0.0 1.9e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI38160.1 - 0.00047 20.3 0.1 0.0015 18.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI38160.1 - 0.0056 16.1 0.2 0.0089 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI38160.1 - 0.0074 16.8 0.1 0.032 14.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI38160.1 - 0.045 13.0 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KPI38160.1 - 0.069 12.4 0.0 0.22 10.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 KPI38160.1 - 0.096 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III FAD_binding_2 PF00890.24 KPI38160.1 - 0.14 11.2 0.2 0.29 10.2 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain PEMT PF04191.13 KPI38161.1 - 1.3e-57 192.8 7.3 5.8e-35 119.9 0.6 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 KPI38161.1 - 0.015 15.1 0.1 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ICMT PF04140.14 KPI38161.1 - 0.32 11.4 5.0 0.23 11.9 0.2 3.0 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PalH PF08733.10 KPI38162.1 - 2.8e-106 355.3 0.0 3.6e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 p450 PF00067.22 KPI38164.1 - 1.6e-53 182.1 0.0 4.2e-53 180.7 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 DUF4777 PF16007.5 KPI38165.1 - 0.00013 22.1 0.1 0.0077 16.5 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4777) Pyr_redox_2 PF07992.14 KPI38166.1 - 5.4e-20 71.8 0.0 1.7e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI38166.1 - 3e-17 62.2 0.0 4.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI38166.1 - 1.2e-16 60.9 0.0 6.6e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI38166.1 - 4.1e-10 39.7 0.0 1.6e-08 34.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI38166.1 - 5.8e-10 38.8 0.0 7.5e-08 31.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KPI38166.1 - 4.2e-08 33.6 0.0 0.016 15.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI38166.1 - 5.8e-08 32.2 0.0 4.3e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KPI38166.1 - 3.1e-06 26.5 0.1 0.097 11.7 0.2 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI38166.1 - 5.9e-05 22.3 0.0 0.00015 21.0 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPI38166.1 - 6e-05 22.4 0.4 0.029 13.7 0.2 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KPI38166.1 - 0.00012 22.1 0.1 2.5 8.1 0.1 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KPI38166.1 - 0.00026 20.5 0.3 0.00044 19.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KPI38166.1 - 0.00028 20.6 3.3 0.011 15.4 0.1 3.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI38166.1 - 0.00033 20.0 0.3 0.0034 16.6 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KPI38166.1 - 0.006 15.3 0.8 1.4 7.6 0.2 3.5 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 KPI38166.1 - 5.2 6.2 5.1 0.37 10.0 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Solute_trans_a PF03619.16 KPI38167.1 - 3.4e-41 141.5 14.9 4.5e-41 141.1 14.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CcmD PF04995.14 KPI38167.1 - 0.13 12.3 0.5 0.13 12.3 0.5 2.9 2 1 0 2 2 2 0 Heme exporter protein D (CcmD) MMR1 PF08505.10 KPI38168.1 - 0.03 14.6 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zn_clus PF00172.18 KPI38169.1 - 1.4e-07 31.5 10.6 2.1e-07 31.0 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 KPI38170.1 - 1.9e-25 89.4 0.0 2.6e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 KPI38171.1 - 5.4e-28 97.9 31.1 8.5e-22 77.6 21.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPI38171.1 - 0.12 12.2 0.7 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3176 PF11374.8 KPI38172.1 - 8.8e-28 96.6 0.3 2.2e-27 95.3 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RRM_1 PF00076.22 KPI38173.1 - 4.4e-28 96.9 0.2 5.2e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI38173.1 - 0.00012 21.9 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 KPI38173.1 - 0.00091 19.1 0.0 0.0024 17.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) RRM_5 PF13893.6 KPI38173.1 - 0.0034 17.0 0.0 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KPI38173.1 - 0.012 15.4 0.0 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) PHM7_cyt PF14703.6 KPI38173.1 - 0.015 15.6 1.0 7.3 6.8 0.0 3.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_8 PF11835.8 KPI38173.1 - 0.15 12.3 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 RRM-like domain PLAC8 PF04749.17 KPI38174.1 - 1.1e-07 32.8 0.5 1.7e-07 32.1 0.5 1.3 1 0 0 1 1 1 1 PLAC8 family BTB PF00651.31 KPI38175.1 - 0.031 14.5 0.0 0.092 13.0 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain COesterase PF00135.28 KPI38176.1 - 6e-78 262.9 0.0 7.3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI38176.1 - 1.2e-06 28.5 0.1 6.2e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KPI38176.1 - 0.028 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Alpha_kinase PF02816.18 KPI38177.1 - 1.2e-49 169.0 0.0 1.4e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Stc1 PF12898.7 KPI38177.1 - 2 9.0 5.3 0.36 11.4 0.4 2.3 3 0 0 3 3 3 0 Stc1 domain Citrate_synt PF00285.21 KPI38178.1 - 2.3e-20 73.0 0.0 2.4e-17 63.0 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KPI38178.1 - 4.3e-18 65.8 0.0 1.6e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KPI38178.1 - 4.3e-15 55.9 0.0 7.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KPI38178.1 - 2.3e-05 24.2 0.0 0.00015 21.6 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MFS_1 PF07690.16 KPI38179.1 - 2.7e-31 108.8 34.1 4.4e-31 108.1 34.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_D PF01813.17 KPI38181.1 - 8.7e-71 237.8 4.0 1.1e-70 237.5 4.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF3919 PF13057.6 KPI38181.1 - 0.035 13.7 1.2 0.056 13.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) CobA_CobO_BtuR PF02572.15 KPI38181.1 - 0.12 12.7 4.2 0.77 10.0 0.1 2.5 1 1 2 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF5446 PF17522.2 KPI38181.1 - 0.2 11.8 2.1 0.35 11.1 0.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) CTU2 PF10288.9 KPI38182.1 - 4.9e-10 39.7 0.0 4.9e-10 39.7 0.0 2.7 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 Coat_F PF07875.12 KPI38182.1 - 0.096 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Coat F domain Aldo_ket_red PF00248.21 KPI38183.1 - 3.1e-66 223.5 0.1 3.5e-66 223.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDC45 PF02724.14 KPI38184.1 - 1.3e-05 23.8 28.7 1.6e-05 23.4 28.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Dapper PF15268.6 KPI38184.1 - 0.00034 19.6 16.7 0.0004 19.4 16.7 1.2 1 0 0 1 1 1 1 Dapper SLC12 PF03522.15 KPI38184.1 - 0.0029 16.7 22.9 0.0044 16.1 22.9 1.3 1 0 0 1 1 1 1 Solute carrier family 12 Raftlin PF15250.6 KPI38184.1 - 0.18 10.6 21.3 0.27 9.9 21.3 1.3 1 0 0 1 1 1 0 Raftlin AUX_IAA PF02309.16 KPI38184.1 - 0.18 11.7 16.7 1 9.2 16.7 2.1 1 1 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.16 KPI38184.1 - 0.22 11.5 20.8 0.078 13.0 18.2 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 KPI38184.1 - 0.27 10.7 16.0 0.45 9.9 16.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 KPI38184.1 - 2.6 6.9 28.4 3.9 6.3 28.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GAGA_bind PF06217.12 KPI38184.1 - 5.5 7.2 35.7 0.23 11.7 30.0 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4569 PF15133.6 KPI38184.1 - 5.5 6.6 26.2 10 5.7 26.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CRT10 PF08728.10 KPI38184.1 - 6.1 4.9 12.8 7.1 4.7 12.8 1.1 1 0 0 1 1 1 0 CRT10 Ndc1_Nup PF09531.10 KPI38184.1 - 7.1 5.2 7.7 8.6 4.9 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.15 KPI38184.1 - 8.7 5.0 30.3 13 4.5 30.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hexokinase_1 PF00349.21 KPI38185.1 - 1.9e-47 161.8 0.0 2.9e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KPI38185.1 - 1.4e-43 149.1 0.0 2.7e-43 148.1 0.0 1.5 1 1 0 1 1 1 1 Hexokinase K_oxygenase PF13434.6 KPI38185.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_M20 PF01546.28 KPI38186.1 - 3.2e-18 66.2 0.0 5.8e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI38186.1 - 4.7e-13 49.0 0.0 9.4e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 KPI38187.1 - 5.2e-30 104.6 24.5 7e-30 104.1 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.6 KPI38187.1 - 0.44 11.0 4.0 17 5.9 0.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) CAF1C_H4-bd PF12265.8 KPI38189.1 - 1.2e-13 51.1 0.0 7.4e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KPI38189.1 - 2.9e-13 50.1 9.8 4.2e-06 27.4 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38189.1 - 6.9e-08 32.7 0.8 0.00042 20.6 0.2 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 KPI38189.1 - 0.058 13.5 1.6 0.098 12.8 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL41A ProRS-C_1 PF09180.11 KPI38190.1 - 3.6e-24 84.7 1.4 1.3e-23 82.9 1.7 1.8 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KPI38190.1 - 6.7e-11 42.2 0.0 3e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KPI38190.1 - 0.0078 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Spb1_C PF07780.12 KPI38192.1 - 2.5e-79 265.8 22.8 2.5e-79 265.8 22.8 3.6 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KPI38192.1 - 5.1e-57 192.8 0.0 1.1e-56 191.8 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KPI38192.1 - 9.1e-52 175.2 18.0 9.1e-52 175.2 18.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) MFS_1 PF07690.16 KPI38193.1 - 1.7e-25 89.7 25.5 1.7e-25 89.7 25.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38193.1 - 3e-20 72.5 17.1 5.4e-20 71.7 13.3 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter Arm PF00514.23 KPI38194.1 - 3.8e-67 220.5 30.8 1.5e-12 47.0 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KPI38194.1 - 1.2e-18 67.2 14.2 6.7e-06 26.5 0.5 6.8 6 1 1 7 7 6 5 HEAT-like repeat HEAT_2 PF13646.6 KPI38194.1 - 9.9e-14 51.5 7.6 0.0026 18.1 0.1 7.4 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.22 KPI38194.1 - 2.2e-12 46.1 16.4 0.29 11.5 0.1 8.6 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.20 KPI38194.1 - 1.1e-07 30.8 10.5 7.4e-05 21.5 3.2 3.0 1 1 2 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.13 KPI38194.1 - 2.1e-07 30.7 6.4 0.012 15.1 0.2 3.8 1 1 2 3 3 3 3 Armadillo-like KAP PF05804.12 KPI38194.1 - 2.4e-06 26.0 2.7 3e-06 25.7 1.3 1.8 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KPI38194.1 - 5.4e-06 25.9 3.1 0.00051 19.4 1.4 3.0 2 1 1 3 3 3 2 V-ATPase subunit H DUF3361 PF11841.8 KPI38194.1 - 3.7e-05 23.7 6.0 1.1 9.2 0.0 4.0 1 1 2 3 3 3 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KPI38194.1 - 0.0022 18.1 4.5 33 4.6 0.1 4.9 3 1 1 5 5 5 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KPI38194.1 - 0.038 14.0 6.3 2 8.5 0.1 4.3 4 1 1 6 6 6 0 Spinocerebellar ataxia type 10 protein domain Amino_oxidase PF01593.24 KPI38194.1 - 0.04 13.2 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HEAT_PBS PF03130.16 KPI38194.1 - 0.057 14.1 10.6 28 5.8 0.1 6.9 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat DUF4853 PF16145.5 KPI38194.1 - 0.071 13.2 0.1 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4853) Lipase_GDSL_2 PF13472.6 KPI38195.1 - 2.8e-15 57.2 0.2 3.7e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPI38195.1 - 2.9e-07 30.7 0.0 3.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KPI38195.1 - 0.009 16.2 0.3 0.18 11.9 0.1 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Q_salvage PF10343.9 KPI38196.1 - 7.9e-63 212.7 0.0 5.2e-59 200.1 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Heme_oxygenase PF01126.20 KPI38197.1 - 0.00023 21.0 0.0 0.00052 19.9 0.0 1.6 1 1 0 1 1 1 1 Heme oxygenase Myco_arth_vir_N PF09610.10 KPI38198.1 - 7.3 6.8 6.4 15 5.7 0.0 3.4 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) zf-HIT PF04438.16 KPI38199.1 - 3.3e-11 42.9 6.7 5.2e-11 42.2 6.7 1.3 1 0 0 1 1 1 1 HIT zinc finger Isochorismatase PF00857.20 KPI38200.1 - 6.4e-24 85.1 0.0 1.2e-23 84.2 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 KPI38201.1 - 2.7e-24 85.8 54.3 1.2e-15 57.4 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 KPI38203.1 - 4.6e-24 85.4 0.1 1.1e-23 84.2 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFA PF04828.14 KPI38203.1 - 4.9e-07 30.0 0.2 1.1e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Citrate_bind PF16114.5 KPI38204.1 - 5.7e-87 289.8 0.1 7.8e-87 289.3 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KPI38204.1 - 2e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KPI38204.1 - 0.0098 14.0 0.1 0.015 13.5 0.1 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) CDC45 PF02724.14 KPI38207.1 - 0.22 9.8 6.0 0.24 9.6 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 KPI38207.1 - 0.32 10.9 3.6 0.51 10.2 3.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CBS PF00571.28 KPI38209.1 - 1.9e-20 73.0 10.0 1.4e-09 38.3 0.1 4.1 4 0 0 4 4 4 3 CBS domain DIOX_N PF14226.6 KPI38210.1 - 3e-31 108.6 0.1 5.2e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI38210.1 - 2.5e-25 88.9 0.0 4.3e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KPI38211.1 - 3.2e-08 33.5 14.0 5.7e-08 32.7 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI38211.1 - 1.1e-05 24.6 0.2 1.7e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA_gamma_C PF02751.14 KPI38212.1 - 7.7e-23 80.4 1.4 1.1e-22 79.8 1.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KPI38212.1 - 1.1e-21 76.6 0.1 1.5e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain aGPT-Pplase2 PF18724.1 KPI38212.1 - 0.071 12.9 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Arg_decarbox_C PF17944.1 KPI38212.1 - 0.088 13.4 0.4 0.2 12.2 0.1 1.8 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension TRI12 PF06609.13 KPI38213.1 - 9e-61 206.0 14.0 1.5e-60 205.3 14.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI38213.1 - 1.7e-21 76.5 17.8 1.7e-21 76.5 17.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38213.1 - 2.4e-15 56.4 6.5 2.4e-15 56.4 6.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Wzz PF02706.15 KPI38213.1 - 0.21 11.9 4.3 0.62 10.4 0.0 3.0 3 0 0 3 3 3 0 Chain length determinant protein NDUF_B12 PF08122.12 KPI38213.1 - 0.28 11.3 1.3 9.1 6.4 0.0 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family ABC2_membrane PF01061.24 KPI38214.1 - 7.1e-50 169.3 56.6 2.3e-32 112.1 20.3 3.8 4 0 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 KPI38214.1 - 3.5e-37 128.0 0.2 2.2e-19 70.3 0.1 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KPI38214.1 - 2.4e-23 81.8 9.2 3.4e-21 74.9 0.0 3.7 3 1 1 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KPI38214.1 - 2.2e-10 41.0 0.0 5.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KPI38214.1 - 6.1e-05 23.5 0.3 0.034 14.5 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KPI38214.1 - 7.7e-05 22.6 0.2 0.4 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPI38214.1 - 0.00026 21.3 0.8 0.074 13.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KPI38214.1 - 0.0021 18.2 0.2 0.63 10.2 0.1 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI38214.1 - 0.0047 16.8 0.1 0.0047 16.8 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase PRK PF00485.18 KPI38214.1 - 0.0054 16.5 0.0 0.94 9.2 0.1 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 KPI38214.1 - 0.0096 15.5 1.6 0.23 11.0 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPI38214.1 - 0.0097 16.4 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KPI38214.1 - 0.011 15.9 0.3 0.31 11.1 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KPI38214.1 - 0.011 16.0 0.4 0.095 12.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KPI38214.1 - 0.013 15.3 0.9 0.013 15.3 0.9 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KPI38214.1 - 0.024 14.0 0.4 13 5.0 0.0 3.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.29 KPI38214.1 - 0.026 15.0 0.4 2.7 8.4 0.3 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KPI38214.1 - 0.029 14.3 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 KPI38214.1 - 0.033 14.1 2.6 2.7 7.9 0.6 2.6 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KPI38214.1 - 0.061 12.8 0.1 8.4 5.8 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KPI38214.1 - 0.075 12.7 0.4 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KPI38214.1 - 0.11 12.3 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase T2SSE PF00437.20 KPI38214.1 - 0.11 11.5 1.0 12 4.9 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.6 KPI38214.1 - 0.12 12.7 0.8 21 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KPI38214.1 - 0.22 11.2 5.8 0.33 10.7 0.1 2.7 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 KPI38214.1 - 0.29 10.9 1.0 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KPI38214.1 - 0.37 10.5 2.1 1.5 8.5 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KPI38214.1 - 1.2 9.2 2.9 2.6 8.1 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KPI38214.1 - 1.8 8.1 7.3 0.74 9.4 1.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.27 KPI38215.1 - 1.1e-54 182.4 5.9 3.1e-19 68.7 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.7 KPI38215.1 - 3.8 7.7 6.8 0.25 11.5 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Ras PF00071.22 KPI38216.1 - 4e-31 107.8 0.1 5e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI38216.1 - 2.1e-23 82.8 0.1 3.4e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI38216.1 - 1.6e-06 27.7 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPI38216.1 - 5.4e-05 22.6 0.2 7.2e-05 22.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KPI38216.1 - 0.0005 19.0 0.1 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Macoilin PF09726.9 KPI38217.1 - 1.6 7.2 6.2 2.2 6.7 6.2 1.1 1 0 0 1 1 1 0 Macoilin family eIF-3c_N PF05470.12 KPI38217.1 - 4 5.6 7.1 6.6 4.9 7.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 KPI38217.1 - 5.9 4.9 16.9 9.2 4.2 16.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi HET PF06985.11 KPI38219.1 - 2.4e-30 105.8 1.0 4.2e-30 105.0 1.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PP2C PF00481.21 KPI38220.1 - 6.4e-64 216.1 0.7 6.8e-53 179.9 0.9 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C ApbA PF02558.16 KPI38221.1 - 6.3e-25 87.6 0.0 1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KPI38221.1 - 2.3e-23 82.7 0.1 3.4e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 KPI38221.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Q_salvage PF10343.9 KPI38222.1 - 4.2e-23 82.3 0.0 5.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family RcnB PF11776.8 KPI38222.1 - 1.3 9.2 4.4 0.44 10.6 0.8 2.1 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator zf-RING_2 PF13639.6 KPI38223.1 - 0.00046 20.4 10.2 0.00046 20.4 10.2 2.2 1 1 1 2 2 2 1 Ring finger domain Trypan_PARP PF05887.11 KPI38223.1 - 0.028 14.4 4.5 0.075 13.0 4.5 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 KPI38223.1 - 0.13 10.6 2.2 0.16 10.2 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein 3Beta_HSD PF01073.19 KPI38225.1 - 1.3e-17 63.7 0.0 2.7e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPI38225.1 - 2.1e-12 47.0 0.0 3.9e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI38225.1 - 1.2e-10 41.0 0.0 3.9e-09 36.1 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPI38225.1 - 8.1e-05 22.2 0.0 0.00022 20.7 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KPI38225.1 - 0.00012 22.0 0.6 0.0015 18.4 0.6 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI38225.1 - 0.0013 18.0 0.0 0.0043 16.2 0.0 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KPI38225.1 - 0.0016 18.3 0.0 0.0069 16.3 0.0 2.1 2 1 0 2 2 2 1 NAD(P)H-binding eIF-1a PF01176.19 KPI38226.1 - 3.5e-14 52.4 0.1 4.7e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Amidase PF01425.21 KPI38227.1 - 5.3e-92 309.1 0.0 1e-91 308.2 0.0 1.5 1 1 0 1 1 1 1 Amidase zf-RING_5 PF14634.6 KPI38228.1 - 2e-05 24.5 0.8 3.2e-05 23.8 0.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI38228.1 - 0.00046 20.2 0.4 0.00079 19.4 0.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPI38228.1 - 0.0012 19.1 0.9 0.0021 18.4 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPI38228.1 - 0.0047 16.8 0.7 0.0086 15.9 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI38228.1 - 0.011 15.6 3.5 0.042 13.7 3.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI38228.1 - 0.021 14.6 4.0 0.085 12.7 4.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI38228.1 - 0.022 14.6 2.5 0.087 12.7 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-piccolo PF05715.13 KPI38228.1 - 0.029 14.5 1.3 0.044 13.9 1.3 1.3 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4_4 PF15227.6 KPI38228.1 - 0.068 13.3 0.6 0.73 10.0 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Lar_restr_allev PF14354.6 KPI38228.1 - 0.16 12.4 2.9 0.27 11.6 2.9 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-UBP PF02148.19 KPI38228.1 - 0.17 12.3 2.5 0.32 11.3 2.1 1.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Fungal_trans_2 PF11951.8 KPI38229.1 - 3.6e-08 32.6 0.1 6.6e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI38229.1 - 1.9e-06 27.9 13.4 3.2e-06 27.2 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 KPI38230.1 - 6.5e-38 130.9 0.0 9.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI38230.1 - 4e-18 66.1 0.3 7.2e-13 48.8 0.1 2.5 1 1 1 2 2 2 2 Amidohydrolase family DHO_dh PF01180.21 KPI38230.1 - 0.075 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Hexokinase_2 PF03727.16 KPI38231.1 - 7.7e-72 241.6 0.0 1.2e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KPI38231.1 - 1.4e-66 224.2 0.0 5.8e-66 222.2 0.0 1.9 2 0 0 2 2 2 1 Hexokinase Aldo_ket_red PF00248.21 KPI38231.1 - 3.6e-63 213.5 0.0 5.6e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4168 PF13767.6 KPI38231.1 - 0.28 12.4 3.9 0.41 11.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Ribosomal_L32e PF01655.18 KPI38232.1 - 7.2e-49 164.7 0.9 7.2e-49 164.7 0.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 PseudoU_synth_2 PF00849.22 KPI38233.1 - 5.8e-25 88.2 0.0 1.6e-24 86.8 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 KPI38233.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 KPI38233.1 - 0.00071 19.2 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain DNA_pol_delta_4 PF04081.13 KPI38234.1 - 3.8e-34 117.9 0.8 3.8e-34 117.9 0.8 2.1 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 Ndc1_Nup PF09531.10 KPI38234.1 - 1.9 7.1 8.2 2.2 6.8 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 KPI38235.1 - 3.1e-09 36.2 59.3 1.6e-08 33.9 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_fungal PF18142.1 KPI38235.1 - 0.82 9.7 4.9 2.1 8.3 4.9 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain WD40 PF00400.32 KPI38236.1 - 1.5e-11 44.6 5.0 3.1e-05 24.7 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38236.1 - 4e-10 39.8 0.0 0.00072 19.8 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KPI38236.1 - 0.0031 15.9 0.0 0.0056 15.0 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KPI38236.1 - 0.041 12.4 0.0 2.2 6.7 0.0 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain WDCP PF15390.6 KPI38236.1 - 0.047 12.1 0.0 0.16 10.3 0.0 1.7 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family IL17R_fnIII_D2 PF16578.5 KPI38236.1 - 0.08 13.5 0.1 0.24 11.9 0.2 1.7 2 0 0 2 2 2 0 Interleukin 17 receptor D Gamma_PGA_hydro PF05908.11 KPI38236.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase SAP PF02037.27 KPI38237.1 - 0.082 12.7 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 SAP domain p450 PF00067.22 KPI38238.1 - 2.3e-71 240.9 0.0 2.7e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 KPI38239.1 - 4.8e-13 49.5 0.0 7.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase DHC_N2 PF08393.13 KPI38240.1 - 4.4e-116 388.3 9.8 4.4e-116 388.3 9.8 4.3 6 1 1 7 7 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KPI38240.1 - 3.6e-110 368.0 0.2 2.2e-109 365.4 0.0 2.5 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KPI38240.1 - 4.1e-108 362.5 0.2 4.1e-108 362.5 0.2 4.9 6 0 0 6 6 6 2 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KPI38240.1 - 1.6e-73 246.5 0.3 1.6e-73 246.5 0.3 3.7 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KPI38240.1 - 7.6e-67 225.4 0.0 3e-66 223.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KPI38240.1 - 4.4e-41 140.4 0.0 2.4e-36 124.9 0.0 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 KPI38240.1 - 3.5e-39 134.8 9.2 3.5e-39 134.8 9.2 2.4 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KPI38240.1 - 1e-31 109.5 0.0 5.3e-28 97.5 0.0 3.6 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KPI38240.1 - 1.2e-29 103.1 1.3 6.5e-10 39.1 0.0 7.1 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KPI38240.1 - 4.7e-27 94.8 0.0 1.1e-26 93.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KPI38240.1 - 6.2e-14 52.6 0.0 0.00093 19.6 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 KPI38240.1 - 5.1e-13 49.2 0.4 1.4e-11 44.6 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KPI38240.1 - 1.6e-12 47.9 0.0 0.021 15.1 0.0 6.4 6 1 0 6 6 5 2 AAA domain AAA_18 PF13238.6 KPI38240.1 - 7.7e-10 39.4 0.0 0.051 14.1 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_33 PF13671.6 KPI38240.1 - 1.1e-09 38.7 0.8 0.3 11.3 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KPI38240.1 - 2.9e-07 31.0 9.5 1.9 8.9 0.0 8.2 9 0 0 9 9 5 1 AAA ATPase domain ABC_tran PF00005.27 KPI38240.1 - 9.6e-06 26.2 0.2 2 8.9 0.0 5.6 4 0 0 4 4 4 1 ABC transporter T2SSE PF00437.20 KPI38240.1 - 1.2e-05 24.5 0.0 0.072 12.1 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein Mg_chelatase PF01078.21 KPI38240.1 - 5.2e-05 22.7 0.5 0.7 9.2 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 KPI38240.1 - 5.3e-05 23.4 0.0 0.0059 16.8 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain AAA_25 PF13481.6 KPI38240.1 - 8.1e-05 22.3 0.0 0.34 10.5 0.0 3.3 2 0 0 2 2 2 2 AAA domain BRE1 PF08647.11 KPI38240.1 - 0.00013 21.9 0.6 0.00013 21.9 0.6 4.2 3 1 0 3 3 1 1 BRE1 E3 ubiquitin ligase AAA_19 PF13245.6 KPI38240.1 - 0.00085 19.7 0.8 0.5 10.7 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 KPI38240.1 - 0.0017 18.0 0.0 0.76 9.6 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KPI38240.1 - 0.0026 17.1 0.0 0.22 10.8 0.0 3.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_24 PF13479.6 KPI38240.1 - 0.0027 17.5 0.4 17 5.1 0.0 4.5 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KPI38240.1 - 0.0031 17.3 0.2 0.97 9.1 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.6 KPI38240.1 - 0.0035 17.1 0.3 53 3.4 0.0 4.7 5 0 0 5 5 4 0 AAA domain PduV-EutP PF10662.9 KPI38240.1 - 0.0048 16.7 0.1 5 6.9 0.1 3.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KPI38240.1 - 0.013 15.7 1.3 4.7 7.4 0.0 4.8 5 0 0 5 5 4 0 AAA domain AAA_21 PF13304.6 KPI38240.1 - 0.033 14.0 0.0 12 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MbeB_N PF04837.12 KPI38240.1 - 0.062 13.6 2.0 0.89 9.9 0.1 3.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Rad17 PF03215.15 KPI38240.1 - 0.065 13.2 1.9 18 5.2 0.0 4.3 6 0 0 6 6 3 0 Rad17 P-loop domain RuvB_N PF05496.12 KPI38240.1 - 0.077 12.7 0.1 4 7.1 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KPI38240.1 - 0.11 12.5 0.5 14 5.7 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LOH1CR12 PF10158.9 KPI38240.1 - 0.19 11.7 3.7 3.5 7.7 0.9 4.0 2 0 0 2 2 2 0 Tumour suppressor protein Vps23_core PF09454.10 KPI38240.1 - 0.37 10.8 1.6 28 4.8 0.5 3.1 2 0 0 2 2 2 0 Vps23 core domain Pol_alpha_B_N PF08418.10 KPI38241.1 - 2.7e-68 230.6 0.0 7.2e-38 130.9 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KPI38241.1 - 3.7e-30 104.9 0.0 5.9e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.20 KPI38242.1 - 3.5e-36 124.3 0.0 4.9e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPI38242.1 - 9.1e-14 51.4 0.2 2.2e-13 50.1 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.31 KPI38243.1 - 1.3e-12 47.7 0.4 2.3e-12 46.8 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain SNARE PF05739.19 KPI38244.1 - 1.9e-07 31.0 0.4 3.5e-07 30.1 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KPI38244.1 - 0.00089 19.1 0.2 0.0015 18.3 0.2 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 T3SSipB PF16535.5 KPI38244.1 - 0.027 15.0 0.1 0.069 13.6 0.1 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF4407 PF14362.6 KPI38244.1 - 0.032 13.6 0.4 0.099 12.0 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fusion_gly PF00523.18 KPI38244.1 - 0.12 10.6 0.0 0.27 9.4 0.0 1.5 1 1 0 1 1 1 0 Fusion glycoprotein F0 FlxA PF14282.6 KPI38244.1 - 0.66 10.0 5.6 1.8 8.6 0.4 2.5 2 0 0 2 2 2 0 FlxA-like protein CS PF04969.16 KPI38245.1 - 4.4e-05 24.4 0.0 6.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 CS domain RRN3 PF05327.11 KPI38245.1 - 1.7 7.1 3.6 1.8 7.0 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPRTase PF14681.6 KPI38246.1 - 1.2e-71 240.5 0.0 1.4e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KPI38246.1 - 2.9e-06 26.9 0.1 6.1e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 KPI38246.1 - 0.00081 18.8 0.3 0.084 12.2 0.1 2.1 2 0 0 2 2 2 2 Thiamine monophosphate synthase GDPD_2 PF13653.6 KPI38246.1 - 0.098 13.2 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family P5CR_dimer PF14748.6 KPI38246.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DEAD PF00270.29 KPI38248.1 - 1.4e-47 161.8 0.0 2.2e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI38248.1 - 9.9e-25 87.0 0.0 7e-24 84.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPI38248.1 - 1.8e-22 79.3 0.0 3.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPI38248.1 - 1.2e-08 35.2 0.0 3.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KPI38248.1 - 0.052 12.8 0.0 0.052 12.8 0.0 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase HlyD_D23 PF16576.5 KPI38248.1 - 0.19 10.9 1.5 0.39 9.9 1.5 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ferric_reduct PF01794.19 KPI38249.1 - 2.2e-21 76.3 18.1 2.2e-21 76.3 18.1 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPI38249.1 - 2e-05 24.6 0.3 0.00014 21.9 0.3 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KPI38249.1 - 0.00028 21.1 2.2 0.19 11.8 0.2 2.6 1 1 0 2 2 2 2 Ferric reductase NAD binding domain MLANA PF14991.6 KPI38249.1 - 0.018 15.3 0.8 0.038 14.3 0.8 1.5 1 0 0 1 1 1 0 Protein melan-A His_Phos_2 PF00328.22 KPI38250.1 - 1.8e-11 44.1 0.0 5.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF92 PF01940.16 KPI38250.1 - 0.017 14.6 0.3 0.054 12.9 0.0 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF92 Mid2 PF04478.12 KPI38250.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ALO PF04030.14 KPI38251.1 - 4e-87 292.3 0.2 5.2e-87 292.0 0.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KPI38251.1 - 7e-17 61.5 0.1 3.2e-14 52.9 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain Ribosomal_S19 PF00203.21 KPI38252.1 - 1.6e-21 75.9 0.1 1.9e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Tannase PF07519.11 KPI38253.1 - 3.1e-99 333.0 1.5 5.5e-99 332.2 1.5 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.20 KPI38253.1 - 0.0002 21.1 0.5 0.00034 20.4 0.5 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KPI38253.1 - 0.0071 16.0 0.1 0.02 14.6 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI38253.1 - 0.053 12.8 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PHP_C PF13263.6 KPI38254.1 - 0.0069 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 PHP-associated MFS_1 PF07690.16 KPI38256.1 - 1.1e-11 44.2 30.8 1.1e-11 44.2 30.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPI38256.1 - 7.6e-10 38.7 7.8 7.6e-10 38.7 7.8 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KPI38256.1 - 0.062 12.2 16.1 0.34 9.7 1.2 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 KPI38257.1 - 4e-22 78.6 16.2 4e-22 78.6 16.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KPI38257.1 - 0.00031 20.3 3.3 0.00031 20.3 3.3 2.1 2 1 0 2 2 2 1 Nodulin-like DUF3040 PF11239.8 KPI38257.1 - 0.49 10.7 0.0 0.49 10.7 0.0 4.3 5 1 0 5 5 5 0 Protein of unknown function (DUF3040) Fungal_trans_2 PF11951.8 KPI38258.1 - 3.4e-29 101.9 2.2 3.7e-29 101.7 2.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KPI38259.1 - 5.7e-10 39.0 0.1 9.1e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38259.1 - 2.4e-09 37.1 0.0 3.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 KPI38259.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KPI38259.1 - 0.038 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 KPI38259.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KPI38259.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KPI38259.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KPI38259.1 - 0.24 11.3 0.1 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NIR_SIR PF01077.22 KPI38260.1 - 7.4e-50 168.6 0.0 1.3e-44 151.5 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 KPI38260.1 - 2.7e-28 99.0 0.0 5.5e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 KPI38260.1 - 4.1e-27 93.8 0.0 3.1e-12 46.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 KPI38260.1 - 2.7e-06 27.3 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GerD PF17898.1 KPI38260.1 - 0.24 11.4 0.4 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 Spore germination GerD central core domain COesterase PF00135.28 KPI38261.1 - 8.6e-78 262.4 0.1 1.2e-77 261.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI38261.1 - 2.3e-06 27.6 0.5 5e-05 23.2 0.2 3.0 3 1 0 3 3 3 1 alpha/beta hydrolase fold DUF2477 PF10631.9 KPI38261.1 - 0.8 10.4 2.6 1.3 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) RNase_PH PF01138.21 KPI38262.1 - 1.2e-25 90.5 0.0 2.3e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MFS_1 PF07690.16 KPI38264.1 - 2.8e-11 42.9 18.4 2.8e-11 42.9 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KPI38264.1 - 5.1 7.3 8.1 0.62 10.3 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Oxidored_FMN PF00724.20 KPI38265.1 - 4e-72 243.3 0.0 5.3e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rep_fac-A_3 PF08661.11 KPI38267.1 - 1.4e-18 67.2 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Mito_carr PF00153.27 KPI38268.1 - 1.3e-51 172.4 4.3 5.7e-19 67.8 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Attacin_N PF03768.15 KPI38268.1 - 0.057 13.6 0.4 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 Attacin, N-terminal region Kinetochor_Ybp2 PF08568.10 KPI38269.1 - 2.5e-68 231.1 0.0 4.1e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin TauD PF02668.16 KPI38271.1 - 2.3e-47 162.0 1.0 3.1e-47 161.6 1.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_2 PF07731.14 KPI38272.1 - 3.3e-42 143.5 5.1 3e-37 127.4 3.7 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KPI38272.1 - 6.3e-21 74.6 8.9 1.7e-19 70.0 0.3 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KPI38272.1 - 1e-14 54.9 0.2 1.5e-11 44.7 0.0 3.4 3 0 0 3 3 3 1 Multicopper oxidase RNA_pol_Rpc4 PF05132.14 KPI38273.1 - 8.9e-25 87.9 0.3 8.9e-25 87.9 0.3 4.9 3 2 2 5 5 5 1 RNA polymerase III RPC4 MIF4G PF02854.19 KPI38275.1 - 7.1e-50 169.6 0.1 1.1e-49 169.0 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KPI38275.1 - 1.8e-22 79.2 2.0 5.4e-22 77.8 2.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.11 KPI38275.1 - 0.0014 17.2 26.8 0.0014 17.2 26.8 1.5 2 0 0 2 2 2 1 Borrelia P83/100 protein Isy1 PF06246.12 KPI38276.1 - 0.0091 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Isy1-like splicing family Fib_alpha PF08702.10 KPI38276.1 - 0.021 15.0 3.1 0.035 14.3 3.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4472 PF14739.6 KPI38276.1 - 0.041 14.6 3.7 0.083 13.6 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Mod_r PF07200.13 KPI38276.1 - 0.07 13.2 5.6 0.12 12.5 5.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1732 PF08340.11 KPI38276.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) AAA_13 PF13166.6 KPI38276.1 - 0.13 10.9 5.7 0.16 10.6 5.7 1.0 1 0 0 1 1 1 0 AAA domain T2SSG PF08334.11 KPI38276.1 - 0.22 11.6 1.9 0.74 9.9 0.7 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein G ZYG-11_interact PF05884.12 KPI38276.1 - 0.24 10.8 2.3 11 5.3 0.0 2.1 2 0 0 2 2 2 0 Interactor of ZYG-11 OmpH PF03938.14 KPI38276.1 - 0.36 11.2 10.8 0.52 10.6 10.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KPI38276.1 - 1.8 7.9 7.1 2.5 7.3 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CN_hydrolase PF00795.22 KPI38277.1 - 9.5e-24 84.1 0.0 3.8e-23 82.1 0.0 2.0 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 KPI38279.1 - 2e-38 132.2 19.8 3e-38 131.6 19.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HSBP1 PF06825.12 KPI38280.1 - 4.5e-12 45.6 1.3 6.1e-12 45.2 1.3 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 EspB PF05802.11 KPI38280.1 - 0.023 14.7 0.5 0.023 14.7 0.5 1.8 1 1 1 2 2 2 0 Enterobacterial EspB protein TTRAP PF14203.6 KPI38280.1 - 0.024 14.6 0.2 0.035 14.1 0.2 1.2 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein SPX PF03105.19 KPI38280.1 - 0.026 14.4 0.2 0.031 14.2 0.2 1.0 1 0 0 1 1 1 0 SPX domain Chlamy_scaf PF09675.10 KPI38280.1 - 0.053 13.9 0.1 0.061 13.7 0.1 1.1 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) HOOK PF05622.12 KPI38280.1 - 0.071 11.2 0.7 0.086 11.0 0.7 1.0 1 0 0 1 1 1 0 HOOK protein CLZ PF16526.5 KPI38280.1 - 0.084 13.2 0.6 0.15 12.4 0.6 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GPS2_interact PF15784.5 KPI38281.1 - 0.017 15.5 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Prefoldin_2 PF01920.20 KPI38281.1 - 0.054 13.4 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit ADIP PF11559.8 KPI38281.1 - 0.084 13.0 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SKA2 PF16740.5 KPI38281.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HAD_2 PF13419.6 KPI38282.1 - 2.9e-08 34.0 0.0 4.2e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI38282.1 - 0.0027 18.0 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amidase PF01425.21 KPI38283.1 - 3.1e-78 263.8 0.0 4.6e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Amidase YozE_SAM_like PF06855.12 KPI38285.1 - 0.45 10.7 2.6 27 5.0 0.0 3.7 1 1 6 7 7 7 0 YozE SAM-like fold Cas_CXXC_CXXC PF09706.10 KPI38285.1 - 1.2 9.4 4.0 6.5 7.1 0.0 4.0 4 3 3 7 7 7 0 CRISPR-associated protein (Cas_CXXC_CXXC) ORC6 PF05460.13 KPI38286.1 - 5.5e-33 114.7 1.9 2.6e-24 86.2 6.7 2.4 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) HTH_AsnC-type PF13404.6 KPI38287.1 - 0.095 12.5 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Tsg PF04668.12 KPI38287.1 - 0.97 10.1 2.8 28 5.4 0.1 2.8 2 1 1 3 3 3 0 Twisted gastrulation (Tsg) protein conserved region DTHCT PF08070.11 KPI38287.1 - 7.8 7.3 25.6 2 9.2 15.6 2.9 1 1 1 2 2 2 0 DTHCT (NUC029) region CLP1_N PF16573.5 KPI38288.1 - 9.6e-33 112.3 0.0 1.8e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KPI38288.1 - 2.5e-31 108.9 0.0 4.2e-30 104.9 0.0 2.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KPI38288.1 - 6.3e-24 84.7 0.0 1.2e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ABC_tran PF00005.27 KPI38288.1 - 0.00038 21.0 0.0 0.00077 20.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Sigma54_activat PF00158.26 KPI38288.1 - 0.0032 17.2 0.2 0.0076 16.0 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 KPI38288.1 - 0.0033 17.8 0.1 0.0058 17.1 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KPI38288.1 - 0.0057 16.4 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KPI38288.1 - 0.006 16.4 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KPI38288.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 KPI38288.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KPI38288.1 - 0.02 14.6 0.0 0.065 13.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 KPI38288.1 - 0.024 14.9 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KPI38288.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KPI38288.1 - 0.037 14.3 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPI38288.1 - 0.039 14.1 0.0 0.085 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KPI38288.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KPI38288.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KPI38288.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KPI38288.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 KPI38288.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KPI38288.1 - 0.13 11.7 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KPI38288.1 - 0.19 12.3 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPI38288.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RSN1_7TM PF02714.15 KPI38289.1 - 1.9e-64 217.6 10.7 1.9e-64 217.6 10.7 1.7 1 1 1 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KPI38289.1 - 5.9e-32 109.7 0.2 9e-32 109.1 0.2 1.3 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Amidohydro_2 PF04909.14 KPI38292.1 - 9.7e-10 38.7 0.0 1.9e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase p450 PF00067.22 KPI38293.1 - 1.2e-45 156.1 0.0 1.6e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GCP_C_terminal PF04130.13 KPI38294.1 - 1.5e-27 96.9 0.1 2.5e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KPI38294.1 - 3.6e-24 85.9 0.0 6.4e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Rhomboid PF01694.22 KPI38295.1 - 3.4e-34 118.0 11.4 3.4e-34 118.0 11.4 2.0 3 0 0 3 3 3 1 Rhomboid family DUF4381 PF14316.6 KPI38295.1 - 0.024 14.9 0.4 0.07 13.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Phage_holin_2_3 PF16080.5 KPI38295.1 - 0.48 10.2 5.0 3.6 7.4 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage holin family HP1 POM121 PF15229.6 KPI38295.1 - 7.4 6.1 14.6 0.21 11.2 5.9 2.1 2 0 0 2 2 2 0 POM121 family GATA PF00320.27 KPI38296.1 - 3.7e-06 26.4 3.7 0.0034 17.0 0.1 2.6 2 0 0 2 2 2 2 GATA zinc finger ArAE_2 PF10334.9 KPI38296.1 - 0.15 11.9 0.1 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 MPDZ_u10 PF16667.5 KPI38296.1 - 5.5 8.0 12.2 0.16 12.9 2.7 3.4 3 0 0 3 3 3 0 Unstructured region 10 on multiple PDZ protein KRE1 PF17056.5 KPI38297.1 - 2.1e-10 40.2 0.1 3.7e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 LptE PF04390.12 KPI38297.1 - 0.15 12.7 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly DFRP_C PF16543.5 KPI38298.1 - 1.7e-21 76.5 7.1 1.7e-21 76.5 7.1 3.8 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KPI38298.1 - 7.6e-06 25.7 2.6 7.6e-06 25.7 2.6 2.5 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KPI38298.1 - 0.00015 21.5 9.8 0.00092 19.0 2.2 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 KPI38298.1 - 0.00061 20.5 17.9 0.0021 18.7 6.3 3.5 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KPI38298.1 - 0.0011 18.9 6.2 0.0011 18.9 6.2 3.5 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 KPI38298.1 - 0.059 13.6 7.2 0.17 12.2 1.1 3.2 2 1 1 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KPI38298.1 - 0.077 13.5 12.8 0.18 12.3 3.7 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pex2_Pex12 PF04757.14 KPI38299.1 - 9.1e-50 169.3 7.5 1.2e-49 169.0 7.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KPI38299.1 - 0.0038 17.5 0.3 0.0059 16.9 0.3 1.3 1 0 0 1 1 1 1 Ring finger domain Swi3 PF07962.12 KPI38299.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Dynamin_M PF01031.20 KPI38299.1 - 0.15 11.2 0.0 7.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Dynamin central region NIF PF03031.18 KPI38300.1 - 5e-40 136.8 0.1 7.2e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aa_trans PF01490.18 KPI38301.1 - 4.3e-21 75.1 30.6 5.3e-21 74.8 30.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MARVEL PF01284.23 KPI38302.1 - 0.00063 19.8 8.4 0.0014 18.7 8.4 1.5 1 1 1 2 2 2 2 Membrane-associating domain DUF4293 PF14126.6 KPI38302.1 - 0.04 14.2 0.9 0.061 13.6 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) TRF PF08558.10 KPI38303.1 - 3.9e-05 23.4 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) adh_short PF00106.25 KPI38304.1 - 2.7e-16 59.6 0.0 4.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38304.1 - 1.3e-13 51.0 0.0 8.6e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38304.1 - 1.5e-06 28.3 0.0 5.7e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KPI38304.1 - 2e-05 24.8 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF4788 PF16032.5 KPI38304.1 - 0.17 10.8 0.0 0.38 9.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4788) GMC_oxred_N PF00732.19 KPI38305.1 - 6.8e-58 196.4 0.0 8.4e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI38305.1 - 3.6e-19 69.7 0.1 6.2e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KPI38305.1 - 0.014 15.0 0.5 0.6 9.6 0.1 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI38305.1 - 0.015 15.8 0.2 6 7.5 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI38305.1 - 0.022 15.0 0.4 0.072 13.3 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI38305.1 - 0.044 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KPI38305.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KPI38305.1 - 0.11 11.7 0.0 0.91 8.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_3 PF00202.21 KPI38307.1 - 5.9e-53 180.0 0.0 1.2e-52 178.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III RSN1_TM PF13967.6 KPI38308.1 - 1.1e-44 151.9 2.2 2e-44 151.1 2.2 1.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPI38308.1 - 2.3e-24 86.6 0.1 3.6e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DNA_pol_A PF00476.20 KPI38308.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family A DUF4164 PF13747.6 KPI38308.1 - 0.099 12.9 0.5 0.21 11.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ADP_ribosyl_GH PF03747.14 KPI38310.1 - 8.3e-41 140.6 0.2 9.6e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Baculo_LEF5 PF04838.12 KPI38310.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 Kinesin PF00225.23 KPI38311.1 - 1.9e-94 316.3 0.1 3.3e-94 315.5 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPI38311.1 - 1.5e-26 93.1 0.0 4.6e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 KPI38311.1 - 0.31 11.1 6.7 0.72 9.9 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain HET PF06985.11 KPI38312.1 - 0.0076 16.6 0.0 0.16 12.3 0.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.18 KPI38313.1 - 3.1e-23 82.1 25.6 4.1e-23 81.8 25.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 KPI38313.1 - 0.015 13.9 1.6 0.029 12.9 1.6 1.4 1 0 0 1 1 1 0 Retinol binding protein receptor TssN PF17555.2 KPI38313.1 - 0.86 8.9 4.9 1.5 8.1 3.2 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN MFS_1 PF07690.16 KPI38314.1 - 0.032 13.2 0.2 0.04 12.8 0.2 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily ADH_N PF08240.12 KPI38315.1 - 1.4e-26 92.5 3.8 2.6e-26 91.6 3.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI38315.1 - 1.4e-13 51.0 0.0 9e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPI38315.1 - 0.00041 19.7 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPI38315.1 - 0.003 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KPI38315.1 - 0.049 13.5 0.2 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KPI38315.1 - 0.1 11.9 1.5 0.26 10.6 1.2 1.8 2 0 0 2 2 2 0 ThiF family adh_short PF00106.25 KPI38317.1 - 1.8e-29 102.6 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38317.1 - 1.9e-23 83.2 0.0 2.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38317.1 - 8.1e-07 29.1 0.0 2.1e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KPI38317.1 - 3e-05 24.1 0.0 5.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KPI38317.1 - 0.026 13.6 0.1 0.06 12.5 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.21 KPI38317.1 - 0.027 13.7 0.7 0.05 12.9 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KPI38317.1 - 0.036 14.5 0.2 0.11 12.9 0.2 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.8 KPI38317.1 - 0.051 13.3 0.6 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LSM PF01423.22 KPI38318.1 - 4.2e-19 68.0 0.5 5.8e-19 67.6 0.5 1.2 1 0 0 1 1 1 1 LSM domain DUF3293 PF11697.8 KPI38318.1 - 0.13 12.7 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) 4F5 PF04419.14 KPI38319.1 - 1.2e-10 42.1 8.1 1.2e-10 42.1 8.1 2.1 2 0 0 2 2 2 2 4F5 protein family DEAD PF00270.29 KPI38320.1 - 4.1e-50 170.0 0.1 3.2e-49 167.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI38320.1 - 3.9e-26 91.6 0.1 3.6e-25 88.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KPI38320.1 - 7.2e-23 80.6 3.0 2.5e-22 78.9 3.0 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 KPI38320.1 - 0.00069 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Glyco_hydro_72 PF03198.14 KPI38321.1 - 2.1e-99 332.7 0.0 2.7e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Podoplanin PF05808.11 KPI38321.1 - 8.6e-05 22.7 1.1 0.00015 21.9 1.1 1.3 1 0 0 1 1 1 1 Podoplanin Cellulase PF00150.18 KPI38321.1 - 0.00086 18.8 0.1 0.01 15.3 0.1 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amnionless PF14828.6 KPI38321.1 - 0.021 13.7 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless VSP PF03302.13 KPI38321.1 - 0.041 12.7 1.1 0.07 12.0 1.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF5362 PF17319.2 KPI38321.1 - 0.069 13.0 0.3 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5362) SKG6 PF08693.10 KPI38321.1 - 0.087 12.2 0.3 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Snf7 PF03357.21 KPI38322.1 - 1.6e-16 60.4 14.3 2.3e-16 59.9 14.3 1.2 1 0 0 1 1 1 1 Snf7 DUF29 PF01724.16 KPI38322.1 - 0.0087 16.3 0.5 0.0087 16.3 0.5 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF29 Exonuc_VII_L PF02601.15 KPI38322.1 - 8.7 5.8 12.2 13 5.3 10.8 1.7 1 1 0 2 2 2 0 Exonuclease VII, large subunit Fungal_trans PF04082.18 KPI38323.1 - 9.5e-63 211.7 0.0 1.7e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPI38323.1 - 0.00012 22.3 13.6 0.0028 18.0 2.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI38323.1 - 0.0045 17.4 2.3 0.0045 17.4 2.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI38323.1 - 0.022 15.6 11.1 0.24 12.3 2.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Ndc1_Nup PF09531.10 KPI38323.1 - 8.7 4.9 6.1 17 4.0 6.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hist_deacetyl PF00850.19 KPI38324.1 - 1e-80 271.5 0.1 2.1e-80 270.5 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain PIP49_C PF12260.8 KPI38324.1 - 0.073 12.7 1.2 0.26 10.9 0.1 2.3 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 Inv-AAD PF18785.1 KPI38325.1 - 1.1e-38 132.1 0.0 1.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KPI38325.1 - 7.8e-14 51.4 0.0 1.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KPI38325.1 - 2.2e-05 24.4 0.0 3.1e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 KPI38325.1 - 0.0081 16.2 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 KPI38325.1 - 0.0096 16.0 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KPI38325.1 - 0.014 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Ring_hydroxyl_A PF00848.19 KPI38326.1 - 4.7e-24 85.5 3.7 2.9e-12 47.0 1.7 2.2 1 1 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KPI38326.1 - 1.4e-13 50.6 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SAP PF02037.27 KPI38327.1 - 0.00019 21.1 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 KPI38327.1 - 0.095 12.0 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 LETM1-like protein JAB PF01398.21 KPI38328.1 - 9.9e-33 112.6 0.0 1.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KPI38328.1 - 6.2e-12 45.9 0.2 1.3e-11 44.9 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KPI38328.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4460 PF14687.6 KPI38328.1 - 0.022 14.8 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Abhydrolase_1 PF00561.20 KPI38329.1 - 6.6e-20 71.8 0.0 1.9e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI38329.1 - 2.2e-12 47.0 0.2 1e-11 44.8 0.2 2.2 1 1 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KPI38329.1 - 0.0082 15.4 0.0 3.2 6.9 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 2-Hacid_dh_C PF02826.19 KPI38330.1 - 3.5e-41 140.5 0.0 4.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI38330.1 - 4.2e-17 62.1 0.0 5.2e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI38330.1 - 0.00023 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AMP-binding PF00501.28 KPI38331.1 - 4.8e-50 170.4 1.2 9.3e-22 77.2 0.0 3.1 2 1 1 3 3 3 3 AMP-binding enzyme BTB PF00651.31 KPI38332.1 - 4.5e-10 39.8 0.6 9.4e-10 38.7 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Lbh PF15317.6 KPI38332.1 - 0.0032 18.3 0.0 0.022 15.6 0.0 2.3 2 0 0 2 2 2 1 Cardiac transcription factor regulator, Developmental protein ATG16 PF08614.11 KPI38332.1 - 0.016 15.4 0.8 0.016 15.4 0.8 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CDC73_N PF16050.5 KPI38332.1 - 1.1 8.6 6.4 0.74 9.1 3.6 1.9 1 1 1 2 2 2 0 Paf1 complex subunit CDC73 N-terminal Podoplanin PF05808.11 KPI38333.1 - 0.018 15.2 1.1 0.027 14.6 1.1 1.2 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 KPI38333.1 - 0.023 13.6 10.2 0.05 12.5 10.2 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 KPI38333.1 - 0.11 11.9 3.4 0.24 10.9 3.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD99L2 PF12301.8 KPI38333.1 - 1 9.6 5.8 0.77 10.0 4.3 1.5 1 1 0 1 1 1 0 CD99 antigen like protein 2 Glyco_hydro_2_C PF02836.17 KPI38334.1 - 4.8e-78 262.3 0.1 6.8e-78 261.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KPI38334.1 - 3.8e-64 216.6 0.1 7.1e-64 215.7 0.1 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 KPI38334.1 - 1.6e-22 79.7 0.0 3.6e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_42 PF02449.15 KPI38334.1 - 0.0081 15.5 0.2 0.031 13.6 0.3 1.8 2 0 0 2 2 2 1 Beta-galactosidase ANAPC5 PF12862.7 KPI38334.1 - 0.037 14.1 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Tox-HNH-EHHH PF15657.6 KPI38334.1 - 0.092 13.1 1.4 0.38 11.1 0.5 2.5 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Ras PF00071.22 KPI38335.1 - 1.8e-55 186.9 0.2 2.4e-55 186.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI38335.1 - 1.1e-36 125.6 0.1 1.9e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI38335.1 - 2.3e-17 63.0 0.1 2.6e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI38335.1 - 1.1e-06 28.3 0.1 5e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPI38335.1 - 2.5e-06 27.5 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KPI38335.1 - 3e-06 26.8 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KPI38335.1 - 1.4e-05 24.6 0.1 1.7e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KPI38335.1 - 0.0014 18.6 0.0 1.2 9.0 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase TIR_2 PF13676.6 KPI38335.1 - 0.036 14.7 0.0 0.073 13.7 0.0 1.5 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 KPI38335.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Fungal_trans PF04082.18 KPI38336.1 - 3.3e-18 65.7 0.0 2e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DprA_WH PF17782.1 KPI38336.1 - 0.095 12.8 0.8 5.8 7.1 0.1 3.0 2 0 0 2 2 2 0 DprA winged helix domain B-block_TFIIIC PF04182.12 KPI38337.1 - 9.6e-13 48.1 0.0 2.1e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KPI38337.1 - 0.0012 18.7 0.3 0.036 14.0 0.0 3.2 2 0 0 2 2 2 1 MarR family Apt1 PF10351.9 KPI38338.1 - 1.6e-191 637.3 1.8 1.6e-191 637.3 1.8 3.1 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27 PF10344.9 KPI38338.1 - 5.1e-183 610.5 0.2 5.9e-182 607.0 0.2 2.1 1 1 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 KPI38338.1 - 1e-158 529.2 11.5 7.5e-150 500.0 4.4 3.1 3 1 1 4 4 4 2 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KPI38338.1 - 3.3e-55 186.2 0.4 9e-55 184.8 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KPI38338.1 - 5.2e-53 179.3 0.0 1.3e-52 178.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KPI38338.1 - 5.3e-33 113.8 0.2 4e-32 111.0 0.1 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain AMP-binding PF00501.28 KPI38339.1 - 1.7e-84 283.9 0.0 2.2e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI38339.1 - 3e-14 53.7 0.3 8.4e-14 52.3 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF812 PF05667.11 KPI38340.1 - 6.2e-05 22.1 33.7 0.0023 16.9 15.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF812) KASH_CCD PF14662.6 KPI38340.1 - 0.00012 21.9 39.2 0.029 14.2 14.0 2.5 2 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH CCDC144C PF14915.6 KPI38340.1 - 0.0039 16.3 23.4 0.0039 16.3 23.4 2.8 2 2 0 2 2 1 1 CCDC144C protein coiled-coil region dCache_1 PF02743.18 KPI38340.1 - 0.019 14.8 2.0 0.04 13.7 2.0 1.6 1 0 0 1 1 1 0 Cache domain Seryl_tRNA_N PF02403.22 KPI38340.1 - 0.021 15.0 11.5 0.021 15.0 11.5 3.5 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain HMMR_N PF15905.5 KPI38340.1 - 0.1 12.1 34.4 0.81 9.1 15.6 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Med28 PF11594.8 KPI38340.1 - 0.45 10.6 13.2 0.44 10.6 1.4 3.0 2 1 1 3 3 3 0 Mediator complex subunit 28 Baculo_PEP_C PF04513.12 KPI38340.1 - 0.89 9.6 18.8 0.053 13.6 3.3 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.9 KPI38340.1 - 0.9 8.0 32.3 2.4 6.6 19.4 2.1 1 1 1 2 2 2 0 Macoilin family CwsA PF10814.8 KPI38340.1 - 1.1 9.4 9.7 2 8.6 0.5 3.3 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA CENP-F_leu_zip PF10473.9 KPI38340.1 - 1.6 8.7 46.8 0.038 14.0 17.4 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RsgA_GTPase PF03193.16 KPI38340.1 - 1.8 8.4 6.2 0.21 11.5 0.2 2.4 2 2 0 2 2 2 0 RsgA GTPase AAA_13 PF13166.6 KPI38340.1 - 3.3 6.3 35.6 0.4 9.3 16.3 2.5 2 1 0 2 2 2 0 AAA domain TolA_bind_tri PF16331.5 KPI38340.1 - 3.7 7.7 31.8 0.12 12.5 0.8 5.1 3 2 1 4 4 4 0 TolA binding protein trimerisation DUF1664 PF07889.12 KPI38340.1 - 4.3 7.4 20.2 5.6 7.0 2.5 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KPI38340.1 - 5.6 6.0 37.4 0.077 12.1 12.2 2.8 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KPI38340.1 - 6.4 7.2 42.8 6.7 7.1 6.2 3.2 2 1 1 3 3 3 0 Fez1 ASD2 PF08687.11 KPI38340.1 - 8.6 5.8 37.0 0.42 10.1 4.0 3.8 1 1 3 4 4 4 0 Apx/Shroom domain ASD2 Cullin PF00888.22 KPI38341.1 - 2e-167 558.5 8.0 2.5e-167 558.2 8.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KPI38341.1 - 7.1e-23 80.4 0.8 3.4e-22 78.3 0.8 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain Antimicrobial_4 PF08024.11 KPI38341.1 - 0.015 15.3 1.1 0.037 14.1 1.1 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide HTH_36 PF13730.6 KPI38341.1 - 0.17 11.9 0.2 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Sugar_tr PF00083.24 KPI38342.1 - 6.8e-76 255.9 22.4 5.8e-49 167.2 2.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI38342.1 - 3.5e-22 78.8 34.6 1.4e-19 70.3 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydratas PF01575.19 KPI38343.1 - 1.5e-05 24.5 0.1 2.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain MR_MLE_C PF13378.6 KPI38344.1 - 2.3e-40 138.5 0.0 3.3e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI38344.1 - 3.2e-08 33.8 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Xpo1 PF08389.12 KPI38347.1 - 1.6e-25 89.9 0.4 2.8e-24 85.9 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KPI38347.1 - 5.2e-12 45.5 0.6 1.6e-11 43.9 0.6 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec8_exocyst PF04048.14 KPI38347.1 - 0.00051 20.0 0.5 0.0018 18.2 0.5 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain HEAT_2 PF13646.6 KPI38347.1 - 0.0074 16.7 2.9 0.04 14.3 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats Death PF00531.22 KPI38347.1 - 0.015 15.5 0.3 7.3 6.8 0.1 3.0 2 0 0 2 2 2 0 Death domain RIX1 PF08167.12 KPI38347.1 - 0.031 14.0 5.5 0.032 14.0 0.0 3.5 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis 14-3-3 PF00244.20 KPI38347.1 - 0.13 11.7 0.5 11 5.4 0.1 2.6 2 0 0 2 2 2 0 14-3-3 protein Adaptin_N PF01602.20 KPI38347.1 - 0.18 10.4 2.6 0.28 9.7 0.1 2.4 3 0 0 3 3 3 0 Adaptin N terminal region UME PF08064.13 KPI38347.1 - 0.23 11.4 2.9 5.3 7.0 0.0 4.1 4 0 0 4 4 4 0 UME (NUC010) domain EptA_B_N PF08019.12 KPI38348.1 - 0.12 12.2 3.2 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Cupin_1 PF00190.22 KPI38349.1 - 4.2e-24 84.9 0.1 6.9e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPI38349.1 - 0.00055 19.6 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Zn_clus PF00172.18 KPI38350.1 - 9.9e-06 25.6 13.5 1.6e-05 24.9 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_GPD PF05954.11 KPI38353.1 - 0.29 10.4 5.9 0.62 9.3 5.9 1.5 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Zn_clus PF00172.18 KPI38354.1 - 0.00042 20.4 12.1 0.0008 19.5 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KPI38354.1 - 0.085 12.3 0.0 0.29 10.6 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ DnaJ PF00226.31 KPI38355.1 - 9.3e-22 76.9 2.4 9.3e-22 76.9 2.4 2.2 2 0 0 2 2 2 1 DnaJ domain XAP5 PF04921.14 KPI38356.1 - 5.1e-79 265.6 3.0 7.8e-79 265.0 3.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator Utp11 PF03998.13 KPI38356.1 - 0.02 14.8 6.1 0.037 14.0 6.1 1.4 1 0 0 1 1 1 0 Utp11 protein NST1 PF13945.6 KPI38356.1 - 0.83 9.7 7.0 1.6 8.8 7.0 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIID_30kDa PF03540.13 KPI38357.1 - 3.3e-22 78.2 0.1 5.8e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Mre11_DNA_bind PF04152.14 KPI38358.1 - 3.4e-51 173.9 2.4 3.4e-51 173.9 2.4 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KPI38358.1 - 3.1e-15 57.2 2.4 5.2e-15 56.5 2.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI38358.1 - 0.00065 19.9 1.5 0.0048 17.1 1.5 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BsuBI_PstI_RE_N PF17728.1 KPI38358.1 - 0.064 13.1 0.2 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease HTH domain PBP1_TM PF14812.6 KPI38358.1 - 4.4 7.8 22.4 0.04 14.3 9.4 3.8 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MSP1_C PF07462.11 KPI38358.1 - 7.7 5.1 16.3 0.13 11.0 3.5 2.4 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus AMP-binding PF00501.28 KPI38359.1 - 3.2e-65 220.4 0.0 4e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI38359.1 - 3.9e-18 66.2 0.7 9e-18 65.0 0.7 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidase PF01425.21 KPI38360.1 - 9.9e-17 61.0 0.5 8.7e-15 54.6 0.1 2.5 2 1 0 2 2 2 1 Amidase Fusion_F0 PF13044.6 KPI38360.1 - 0.02 13.6 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus PEX11 PF05648.14 KPI38361.1 - 0.0002 20.9 3.0 0.00038 20.0 0.6 2.4 2 1 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) CENP-T_C PF15511.6 KPI38363.1 - 7.9e-31 106.4 0.1 3e-30 104.5 0.0 2.0 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KPI38363.1 - 2.4e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein ORC6 PF05460.13 KPI38363.1 - 3 7.0 14.9 0.2 10.9 9.8 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) IPK PF03770.16 KPI38364.1 - 2.1e-55 187.7 0.0 2.7e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1798 PF08807.10 KPI38364.1 - 0.058 13.5 0.0 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Kinesin PF00225.23 KPI38365.1 - 5.6e-92 308.2 0.0 1.9e-91 306.5 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KPI38365.1 - 6.7e-21 74.8 0.0 1.4e-16 60.8 0.0 2.9 2 0 0 2 2 2 2 Microtubule binding CEP63 PF17045.5 KPI38365.1 - 0.00015 21.8 25.0 0.00015 21.8 25.0 5.0 4 1 0 4 4 4 1 Centrosomal protein of 63 kDa Sulfatase PF00884.23 KPI38366.1 - 4.1e-24 85.5 0.0 5.3e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KPI38366.1 - 0.00017 20.4 0.0 0.00019 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 KPI38366.1 - 0.0077 16.1 0.1 0.029 14.3 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function Sulfatase_C PF14707.6 KPI38366.1 - 0.01 16.6 0.1 0.36 11.6 0.1 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase MMR_HSR1 PF01926.23 KPI38367.1 - 5.5e-09 36.1 0.0 1.8e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KPI38367.1 - 1.2e-05 24.7 0.5 5.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KPI38367.1 - 1.3e-05 25.1 0.0 3.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KPI38367.1 - 0.00024 21.2 5.7 0.046 13.8 0.3 3.2 2 2 1 3 3 3 2 Dynamin family SRPRB PF09439.10 KPI38367.1 - 0.0053 16.2 0.2 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit IIGP PF05049.13 KPI38367.1 - 0.01 14.9 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KPI38367.1 - 0.018 15.3 2.9 0.67 10.2 0.0 3.0 2 2 1 3 3 3 0 AAA domain Septin PF00735.18 KPI38367.1 - 0.055 12.7 0.0 0.24 10.6 0.0 2.1 2 1 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 KPI38367.1 - 0.06 12.7 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KPI38367.1 - 0.076 13.4 6.1 0.5 10.7 0.0 3.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KPI38367.1 - 0.081 12.5 0.1 0.73 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPI38367.1 - 0.091 13.3 0.3 0.73 10.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 KPI38367.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KPI38367.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KPI38367.1 - 0.11 11.9 0.2 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Pex19 PF04614.12 KPI38367.1 - 0.11 12.2 5.5 0.17 11.6 5.5 1.3 1 0 0 1 1 1 0 Pex19 protein family ATP_bind_1 PF03029.17 KPI38367.1 - 0.14 12.0 0.2 0.59 9.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KPI38367.1 - 0.21 12.1 2.9 1.5 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KPI38367.1 - 3.7 7.6 5.5 1.1 9.3 0.1 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain Fungal_trans PF04082.18 KPI38368.1 - 1.5e-17 63.6 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 5-FTHF_cyc-lig PF01812.20 KPI38369.1 - 4.9e-34 117.8 0.0 6.9e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Fungal_trans_2 PF11951.8 KPI38370.1 - 0.089 11.6 1.4 0.17 10.7 0.3 1.9 1 1 0 2 2 2 0 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KPI38372.1 - 2.1e-51 174.8 0.0 2.2e-49 168.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38372.1 - 2.2e-41 141.5 0.1 1e-39 136.0 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI38372.1 - 4.7e-12 46.2 0.5 1.2e-11 44.9 0.5 1.5 1 1 0 1 1 1 1 KR domain UreD PF01774.17 KPI38373.1 - 8.5e-61 205.6 0.0 1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein BiPBP_C PF06832.12 KPI38373.1 - 0.069 13.2 0.1 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family STAG PF08514.11 KPI38374.1 - 6.1e-35 119.6 0.5 6.1e-35 119.6 0.5 3.0 2 0 0 2 2 2 1 STAG domain DUF5596 PF18082.1 KPI38374.1 - 0.031 14.1 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) EMC3_TMCO1 PF01956.16 KPI38374.1 - 0.76 9.5 4.8 0.42 10.3 0.5 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like GFA PF04828.14 KPI38375.1 - 6.1e-14 52.1 9.5 1.9e-07 31.3 3.6 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF2072 PF09845.9 KPI38375.1 - 0.067 13.4 0.1 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein MFS_1 PF07690.16 KPI38376.1 - 5.7e-52 176.8 31.8 1.9e-50 171.8 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38376.1 - 2.2e-13 49.9 4.2 2.2e-13 49.9 4.2 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KPI38376.1 - 0.029 12.7 0.7 0.097 10.9 0.7 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DEAD PF00270.29 KPI38378.1 - 1.9e-26 92.9 0.0 3.3e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KPI38378.1 - 9.5e-21 74.4 0.4 2.7e-20 72.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KPI38378.1 - 6.3e-12 45.8 0.0 3.8e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 KPI38378.1 - 1.1e-05 25.8 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KPI38378.1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ebp2 PF05890.12 KPI38379.1 - 1.9e-83 280.1 11.8 1.9e-83 280.1 11.8 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Nop14 PF04147.12 KPI38379.1 - 0.0027 16.0 24.3 0.0027 16.0 24.3 2.1 2 0 0 2 2 2 1 Nop14-like family DUF1517 PF07466.11 KPI38379.1 - 8.4 6.5 8.9 3 7.9 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1517) MARVEL PF01284.23 KPI38380.1 - 3.1e-15 56.5 14.1 3.8e-15 56.2 14.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.8 KPI38380.1 - 0.064 13.1 0.6 0.32 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF2207 PF09972.9 KPI38380.1 - 0.17 10.6 1.1 0.23 10.2 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4199 PF13858.6 KPI38380.1 - 2.5 8.5 9.6 4.4 7.7 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CPBP PF02517.16 KPI38380.1 - 9.1 6.7 10.0 32 5.0 10.0 1.9 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease TauD PF02668.16 KPI38381.1 - 1.6e-25 90.5 0.0 2.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RIO1 PF01163.22 KPI38382.1 - 6.7e-43 146.5 0.0 1.1e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KPI38382.1 - 8.1e-30 102.9 0.0 1.5e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KPI38382.1 - 5.4e-06 26.5 1.4 0.029 14.3 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KPI38382.1 - 0.00011 21.6 0.3 0.078 12.3 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family UBX PF00789.20 KPI38383.1 - 0.0031 17.7 0.0 0.0074 16.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain UPF0444 PF15475.6 KPI38383.1 - 0.0095 16.2 1.5 0.025 14.9 1.5 1.6 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 PRP1_N PF06424.12 KPI38383.1 - 1.5 9.2 12.7 0.7 10.3 5.0 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Polysacc_deac_1 PF01522.21 KPI38384.1 - 1e-12 48.0 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SURF1 PF02104.15 KPI38385.1 - 1.6e-17 64.3 0.0 1.8e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Synaptobrevin PF00957.21 KPI38386.1 - 7.4e-32 109.0 0.0 1e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KPI38386.1 - 1.1e-27 95.8 0.1 1.8e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain PI3Ka PF00613.20 KPI38387.1 - 2.6e-50 170.4 0.1 4.5e-50 169.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KPI38387.1 - 9.2e-44 150.1 0.0 1.7e-31 109.9 0.0 3.0 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KPI38387.1 - 6.3e-32 110.4 0.0 1.2e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 RHH_5 PF07878.11 KPI38387.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Thioredoxin_15 PF18403.1 KPI38387.1 - 0.16 11.9 0.6 0.33 10.8 0.6 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Sulfatase PF00884.23 KPI38388.1 - 7.8e-40 137.2 0.0 1.2e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.16 KPI38388.1 - 3.1e-23 82.3 23.8 4.3e-23 81.8 23.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 KPI38388.1 - 0.024 13.6 0.5 0.047 12.6 0.1 1.6 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM DUF3425 PF11905.8 KPI38389.1 - 1.2e-20 73.7 0.2 2.3e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI38389.1 - 2.3e-05 24.4 4.3 3.5e-05 23.8 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor CASP_C PF08172.12 KPI38389.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 CASP C terminal G_path_suppress PF15991.5 KPI38389.1 - 0.024 14.8 0.6 0.034 14.3 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor Cnn_1N PF07989.11 KPI38389.1 - 0.051 13.7 1.8 0.097 12.8 0.2 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CDC37_N PF03234.14 KPI38389.1 - 0.29 12.0 2.5 0.56 11.1 2.5 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding bZIP_2 PF07716.15 KPI38389.1 - 0.62 10.2 8.1 7.2 6.8 4.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Rap1_C PF11626.8 KPI38389.1 - 2.8 8.1 4.4 3.3 7.9 2.7 2.0 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mpv17_PMP22 PF04117.12 KPI38390.1 - 3.2e-12 46.5 1.6 1.8e-11 44.1 1.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family NADH_oxidored PF08040.11 KPI38390.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 MNLL subunit Host_attach PF10116.9 KPI38391.1 - 0.026 15.1 0.0 0.15 12.6 0.0 2.4 1 0 0 1 1 1 0 Protein required for attachment to host cells WD40 PF00400.32 KPI38391.1 - 0.074 14.0 0.1 0.33 11.9 0.1 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat FAD_binding_3 PF01494.19 KPI38392.1 - 2.7e-19 69.6 0.0 5.9e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI38392.1 - 6.6e-05 22.6 1.7 0.0019 17.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI38392.1 - 0.00049 20.3 0.1 0.0013 18.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI38392.1 - 0.0015 17.8 0.1 0.046 12.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI38392.1 - 0.0048 16.0 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KPI38392.1 - 0.021 13.7 0.4 0.62 8.8 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 KPI38392.1 - 0.06 12.6 0.1 0.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF4229 PF14012.6 KPI38392.1 - 0.093 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Pyr_redox_3 PF13738.6 KPI38392.1 - 0.15 11.3 0.1 0.66 9.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI38392.1 - 1.1 8.2 6.4 0.38 9.8 1.9 2.2 2 1 1 3 3 3 0 FAD binding domain TFB6 PF17110.5 KPI38393.1 - 6.1e-31 107.5 0.0 8.9e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH HA2 PF04408.23 KPI38394.1 - 2.1e-16 60.1 0.0 2.1e-16 60.1 0.0 2.9 4 0 0 4 4 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPI38394.1 - 6.3e-16 58.5 0.1 1.6e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPI38394.1 - 4.9e-13 49.4 0.0 1.3e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI38394.1 - 2e-09 37.4 0.2 5.2e-07 29.6 0.2 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 KPI38394.1 - 6.4e-08 32.9 0.0 2.4e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 RWD domain AAA_29 PF13555.6 KPI38394.1 - 0.00015 21.4 0.1 0.00058 19.5 0.0 2.0 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KPI38394.1 - 0.00024 21.4 2.9 0.00098 19.4 1.6 2.6 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KPI38394.1 - 0.00066 19.1 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 KPI38394.1 - 0.00082 19.7 0.1 0.0018 18.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.7 KPI38394.1 - 0.0015 18.8 0.0 0.0042 17.3 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsRBD2 PF17842.1 KPI38394.1 - 0.008 16.4 0.1 0.008 16.4 0.1 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding domain 2 AAA_30 PF13604.6 KPI38394.1 - 0.016 14.9 0.8 0.069 12.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KPI38394.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KPI38394.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein HOIP-UBA PF16678.5 KPI38394.1 - 0.11 12.5 2.8 0.66 10.0 0.0 3.0 3 0 0 3 3 3 0 HOIP UBA domain pair ABC_tran PF00005.27 KPI38394.1 - 0.13 12.8 0.0 0.6 10.6 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Bet_v_1 PF00407.19 KPI38394.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family AAA_23 PF13476.6 KPI38394.1 - 0.86 10.1 7.3 0.047 14.2 0.7 2.3 2 1 0 2 2 2 0 AAA domain ADH_N PF08240.12 KPI38396.1 - 3.2e-23 81.7 1.1 5.5e-23 80.9 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI38396.1 - 1.1e-17 64.2 0.3 1.7e-17 63.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI38396.1 - 0.0014 18.1 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPI38396.1 - 0.029 14.6 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain BKACE PF05853.12 KPI38396.1 - 0.041 13.2 0.0 0.058 12.7 0.0 1.3 1 1 0 1 1 1 0 beta-keto acid cleavage enzyme ADH_N_2 PF16884.5 KPI38396.1 - 0.048 13.6 0.1 0.32 10.9 0.0 2.3 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase Methyltransf_25 PF13649.6 KPI38396.1 - 0.087 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Thg1C PF14413.6 KPI38398.1 - 2.7e-49 166.4 0.2 4e-49 165.8 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KPI38398.1 - 6.9e-49 165.0 0.0 1.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Gal-3-0_sulfotr PF06990.11 KPI38398.1 - 0.043 12.7 0.1 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase DUF2704 PF10866.8 KPI38398.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2704) Cyclin_N PF00134.23 KPI38399.1 - 1.5e-44 150.8 0.6 2.7e-44 150.0 0.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPI38399.1 - 2e-33 115.0 0.0 4.8e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mem_trans PF03547.18 KPI38400.1 - 3.1e-53 180.6 2.0 3.9e-53 180.2 2.0 1.1 1 0 0 1 1 1 1 Membrane transport protein CMAS PF02353.20 KPI38401.1 - 2.7e-14 53.1 0.0 5.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KPI38401.1 - 2.4e-12 47.0 0.0 4.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI38401.1 - 4e-11 43.5 0.2 4.1e-06 27.4 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KPI38401.1 - 6.3e-11 42.8 0.1 1e-07 32.5 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI38401.1 - 2.8e-09 36.9 0.0 9.5e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KPI38401.1 - 2.2e-08 34.7 0.1 0.00028 21.6 0.1 2.5 1 1 1 2 2 2 2 Methyltransferase domain MetW PF07021.12 KPI38401.1 - 0.0092 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KPI38401.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KPI38401.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_2_N PF02837.18 KPI38402.1 - 1.4e-47 161.7 2.2 1.9e-47 161.3 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KPI38402.1 - 6.1e-05 23.6 0.0 0.00017 22.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Stn1 PF10451.9 KPI38403.1 - 7.9e-09 34.8 0.0 1.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Rrp15p PF07890.12 KPI38403.1 - 0.19 12.1 9.2 0.31 11.4 9.2 1.3 1 0 0 1 1 1 0 Rrp15p DUF334 PF03904.13 KPI38403.1 - 2.2 7.8 6.3 2.5 7.6 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF334) adh_short PF00106.25 KPI38404.1 - 2.1e-40 138.3 0.0 3.4e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38404.1 - 3e-25 89.2 0.0 4.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38404.1 - 1.6e-06 28.2 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI38404.1 - 1.9e-05 24.7 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI38404.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KPI38404.1 - 0.018 15.0 0.2 0.049 13.6 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TrbH PF07283.11 KPI38404.1 - 0.055 13.6 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH NmrA PF05368.13 KPI38404.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family DUF1776 PF08643.10 KPI38404.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 KPI38404.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CoA_transf_3 PF02515.17 KPI38406.1 - 3.5e-41 141.6 0.1 4.1e-39 134.7 0.0 2.4 2 1 0 2 2 2 2 CoA-transferase family III GST_N_2 PF13409.6 KPI38407.1 - 8.6e-16 58.0 0.1 1.9e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI38407.1 - 1.3e-15 57.5 0.0 7.3e-15 55.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI38407.1 - 8.7e-12 45.2 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KPI38407.1 - 0.00014 22.0 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin FMN_red PF03358.15 KPI38408.1 - 1.4e-29 102.9 0.0 1.7e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KPI38408.1 - 4.4e-07 29.8 0.0 7.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold MAS20 PF02064.15 KPI38409.1 - 5.9e-42 142.8 0.3 6.9e-42 142.6 0.3 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor PsbN PF02468.15 KPI38409.1 - 0.27 11.1 2.6 0.49 10.3 2.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DEK_C PF08766.11 KPI38409.1 - 0.3 11.0 1.7 1.8 8.6 0.0 2.6 2 1 1 3 3 3 0 DEK C terminal domain AMP-binding PF00501.28 KPI38410.1 - 9.4e-86 288.0 0.0 1.2e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI38410.1 - 1.2e-12 48.7 0.3 2.8e-12 47.4 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sep15_SelM PF08806.11 KPI38410.1 - 0.082 13.1 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Sep15/SelM redox domain adh_short PF00106.25 KPI38411.1 - 5.5e-20 71.7 0.0 1.2e-18 67.3 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38411.1 - 1.2e-12 47.9 0.0 1.2e-10 41.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38411.1 - 1.4e-06 28.4 0.0 4.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 KR domain Arylsulfotran_2 PF14269.6 KPI38412.1 - 5.1e-48 164.0 1.7 6.3e-48 163.7 1.7 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KPI38412.1 - 7.3e-19 67.9 0.4 2.2e-18 66.3 0.4 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DBR1 PF05011.13 KPI38413.1 - 3.4e-44 150.7 0.1 1e-43 149.1 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KPI38413.1 - 1.1e-06 29.3 1.2 2e-06 28.5 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAM2 PF07145.15 KPI38413.1 - 0.045 13.4 0.0 3.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DIOX_N PF14226.6 KPI38414.1 - 8.9e-19 68.4 0.1 2e-18 67.3 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI38414.1 - 0.001 19.5 0.1 0.0037 17.7 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Caleosin PF05042.13 KPI38415.1 - 1.6e-61 207.2 0.4 2e-61 206.8 0.4 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_8 PF13833.6 KPI38415.1 - 0.00065 19.5 0.5 0.02 14.7 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KPI38415.1 - 0.013 15.0 0.5 0.064 12.8 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KPI38415.1 - 0.026 14.4 0.7 0.38 10.8 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Fungal_trans_2 PF11951.8 KPI38416.1 - 9.4e-05 21.4 0.5 9.4e-05 21.4 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain HAD PF12710.7 KPI38417.1 - 8.5e-11 42.6 0.0 2.1e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KPI38417.1 - 3.8e-05 24.1 0.0 0.00018 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Hydrolase PF00702.26 KPI38417.1 - 0.00026 21.3 0.0 0.00043 20.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1241 PF06840.11 KPI38417.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Hydrolase_3 PF08282.12 KPI38417.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Exo84_C PF16528.5 KPI38418.1 - 6e-59 199.3 2.2 6e-59 199.3 2.2 2.0 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KPI38418.1 - 1.1e-14 54.3 2.1 1.1e-14 54.3 2.1 2.3 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 KPI38418.1 - 0.014 15.2 1.7 0.66 9.7 0.4 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF2608 PF11019.8 KPI38418.1 - 0.056 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF2205 PF10224.9 KPI38418.1 - 0.98 9.5 4.6 0.68 10.0 1.0 2.7 3 1 0 3 3 3 0 Short coiled-coil protein Zn_clus PF00172.18 KPI38419.1 - 1.1e-05 25.5 11.5 2.2e-05 24.5 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MLTD_N PF06474.12 KPI38419.1 - 0.0088 16.2 0.4 0.55 10.4 0.1 2.9 3 0 0 3 3 3 1 MltD lipid attachment motif Fungal_trans_2 PF11951.8 KPI38420.1 - 2.2e-51 174.9 0.1 3.6e-51 174.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 KPI38422.1 - 3.3e-93 312.9 42.8 1.4e-92 310.8 42.8 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI38422.1 - 1.7e-16 60.1 42.2 3.5e-16 59.1 42.2 1.5 1 1 0 1 1 1 1 Amino acid permease 4HBT PF03061.22 KPI38424.1 - 7.5e-10 39.0 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KPI38424.1 - 0.00016 22.2 0.0 0.00019 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KPI38424.1 - 0.0013 18.0 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase MMR_HSR1 PF01926.23 KPI38425.1 - 5.7e-07 29.6 0.0 5.7e-07 29.6 0.0 2.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KPI38425.1 - 0.0034 17.9 0.1 0.0034 17.9 0.1 2.6 1 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KPI38425.1 - 0.014 15.4 0.0 0.014 15.4 0.0 3.9 2 2 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 KPI38425.1 - 0.029 14.3 2.2 0.045 13.7 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase Exonuc_VII_L PF02601.15 KPI38425.1 - 0.17 11.4 12.5 0.21 11.1 12.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran PF00005.27 KPI38425.1 - 0.44 11.0 0.0 0.44 11.0 0.0 2.9 2 1 0 2 2 2 0 ABC transporter ZnuA PF01297.17 KPI38425.1 - 0.52 9.7 5.7 0.88 8.9 5.7 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF4407 PF14362.6 KPI38425.1 - 1.9 7.8 13.8 3.2 7.0 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CFAP91 PF14738.6 KPI38425.1 - 8.7 6.4 24.3 3.1 7.8 6.3 2.2 1 1 1 2 2 2 0 Cilia- and flagella-associated protein 91 IL1 PF00340.19 KPI38426.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Interleukin-1 / 18 MFS_1 PF07690.16 KPI38427.1 - 1.9e-16 60.0 28.6 1.9e-16 60.0 28.6 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Bacteriocin_IId PF09221.10 KPI38427.1 - 0.07 13.3 1.9 25 5.2 0.0 3.6 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like DUF4389 PF14333.6 KPI38427.1 - 5.8 6.9 8.5 20 5.2 0.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4389) ThiF PF00899.21 KPI38428.1 - 6.6e-111 369.5 0.0 2.1e-74 250.0 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KPI38428.1 - 2.7e-93 312.5 1.2 1.1e-91 307.2 1.4 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KPI38428.1 - 9.5e-30 103.2 0.2 2e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KPI38428.1 - 5.5e-28 97.0 0.0 1.2e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KPI38428.1 - 3.4e-24 84.8 0.9 1.4e-23 82.8 0.9 2.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle DUF3782 PF12644.7 KPI38428.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) SPT_ssu-like PF11779.8 KPI38429.1 - 5e-17 61.3 2.3 8.1e-17 60.6 2.3 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RE_Bsp6I PF09504.10 KPI38429.1 - 0.22 11.1 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Bsp6I restriction endonuclease WD40 PF00400.32 KPI38430.1 - 2.6e-24 85.0 25.3 0.0089 16.9 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38430.1 - 1.4e-06 28.5 7.0 0.0014 18.9 0.0 4.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2264 PF10022.9 KPI38431.1 - 2.7e-129 431.3 0.2 3.5e-129 430.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) LSM PF01423.22 KPI38432.1 - 2.2e-14 52.9 0.1 2.6e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KPI38432.1 - 0.0049 16.5 0.1 0.0071 16.0 0.1 1.3 1 0 0 1 1 1 1 Hfq protein CRCB PF02537.15 KPI38433.1 - 3.3e-37 126.7 12.0 1.8e-23 82.6 4.2 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) YqzE PF14038.6 KPI38434.1 - 0.1 12.6 0.2 0.1 12.6 0.2 4.5 5 0 0 5 5 5 0 YqzE-like protein Packaging_FI PF14000.6 KPI38435.1 - 0.21 12.1 4.7 0.33 11.4 4.7 1.3 1 0 0 1 1 1 0 DNA packaging protein FI TRF PF08558.10 KPI38437.1 - 0.00013 21.6 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) ADH_zinc_N_2 PF13602.6 KPI38438.1 - 5.5e-14 53.3 0.1 1.7e-13 51.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI38438.1 - 0.014 15.2 0.0 0.07 13.0 0.0 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.7 KPI38439.1 - 0.00058 19.7 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like TetR_C_32 PF09209.11 KPI38439.1 - 0.046 13.7 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ECH_1 PF00378.20 KPI38440.1 - 6.4e-24 84.6 0.1 7.6e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI38440.1 - 1.6e-10 41.0 0.2 1.7e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GCV_T PF01571.21 KPI38441.1 - 1e-72 244.6 0.0 1.6e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KPI38441.1 - 2.8e-44 152.2 0.4 4.6e-44 151.4 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KPI38441.1 - 2.9e-21 75.2 0.4 7.3e-21 73.9 0.0 2.0 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KPI38441.1 - 6.1e-20 71.3 0.0 1.2e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain SoxG PF04268.12 KPI38441.1 - 9e-07 29.1 0.0 0.0001 22.5 0.0 2.8 2 1 1 3 3 2 1 Sarcosine oxidase, gamma subunit family Pyr_redox_2 PF07992.14 KPI38441.1 - 2.6e-05 23.6 0.6 0.1 11.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI38441.1 - 6.4e-05 23.4 0.5 0.046 14.3 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI38441.1 - 0.0018 17.2 0.1 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 KPI38441.1 - 0.003 17.8 0.1 0.0082 16.4 0.0 1.8 2 0 0 2 2 1 1 TrkA-N domain NAD_binding_9 PF13454.6 KPI38441.1 - 0.005 16.8 0.3 0.47 10.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KPI38441.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KPI38441.1 - 0.032 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 KPI38441.1 - 0.063 12.5 0.7 0.3 10.3 0.7 1.9 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KPI38441.1 - 0.069 13.4 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI38441.1 - 0.23 10.4 0.6 4.7 6.1 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pmp3 PF01679.17 KPI38442.1 - 3.5e-21 75.1 8.7 4.4e-21 74.8 8.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MFS_1 PF07690.16 KPI38443.1 - 1e-33 116.7 54.6 3.8e-19 68.8 24.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MoCF_biosynth PF00994.24 KPI38444.1 - 1e-53 180.9 0.1 4.7e-29 100.9 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KPI38444.1 - 6e-37 126.8 4.1 1.1e-36 126.0 4.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KPI38444.1 - 8.7e-17 61.1 0.0 2.5e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KPI38444.1 - 2.4 7.5 10.2 3.6 6.9 10.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aminotran_5 PF00266.19 KPI38447.1 - 4.6e-20 71.9 0.0 4e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V ATPase PF06745.13 KPI38447.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 KaiC ubiquitin PF00240.23 KPI38448.1 - 5.9e-19 67.6 0.1 9.8e-19 66.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPI38448.1 - 1.2e-06 28.3 0.1 3e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Polysacc_deac_1 PF01522.21 KPI38449.1 - 1.7e-09 37.7 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Dak1 PF02733.17 KPI38450.1 - 6.3e-98 327.5 1.0 8.3e-98 327.1 1.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KPI38450.1 - 1.2e-47 162.1 4.3 1.4e-47 161.9 1.9 2.3 3 0 0 3 3 3 1 DAK2 domain Fez1 PF06818.15 KPI38451.1 - 9.9 6.6 107.4 0.25 11.8 17.2 7.5 1 1 4 5 5 5 0 Fez1 zf-ZPR1 PF03367.13 KPI38452.1 - 4e-104 345.3 0.0 1.4e-53 181.0 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KPI38452.1 - 0.063 13.3 3.3 0.24 11.4 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF4028 PF13220.6 KPI38452.1 - 0.12 12.2 0.0 5.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) Atrophin-1 PF03154.15 KPI38452.1 - 0.91 7.7 3.2 1.1 7.5 3.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Rubredoxin_2 PF18073.1 KPI38452.1 - 6.4 6.6 10.7 7.4 6.4 0.6 3.0 3 0 0 3 3 3 0 Rubredoxin metal binding domain Arb1 PF09692.10 KPI38453.1 - 8.4e-112 374.3 0.0 1e-111 374.0 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 BRF1 PF07741.13 KPI38453.1 - 0.51 10.7 4.3 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Acetyltransf_3 PF13302.7 KPI38454.1 - 2.5e-10 41.2 0.0 3.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TMEM154 PF15102.6 KPI38455.1 - 0.00024 21.0 0.1 0.0057 16.6 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family DUF4381 PF14316.6 KPI38455.1 - 0.02 15.1 0.6 3.6 7.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) DUF2956 PF11169.8 KPI38455.1 - 0.041 14.1 0.0 0.041 14.1 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) DUF4064 PF13273.6 KPI38455.1 - 0.048 13.9 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2627 PF11118.8 KPI38455.1 - 0.049 14.2 0.0 0.081 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DAG1 PF05454.11 KPI38455.1 - 0.052 12.9 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TadE PF07811.12 KPI38455.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TadE-like protein FeoB_associated PF12669.7 KPI38455.1 - 0.37 11.2 2.1 0.6 10.5 2.1 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein ABC_tran_CTD PF16326.5 KPI38455.1 - 0.63 10.3 5.3 1.6 9.0 0.9 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain OHCU_decarbox PF09349.10 KPI38456.1 - 3.7e-45 154.2 0.0 4.3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase EzrA PF06160.12 KPI38457.1 - 0.017 13.3 5.6 0.029 12.5 5.6 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GFA PF04828.14 KPI38458.1 - 0.00024 21.4 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KPI38458.1 - 0.0063 16.2 0.3 0.016 14.9 0.3 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain p450 PF00067.22 KPI38459.1 - 1.1e-62 212.4 0.0 3e-62 210.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Rot1 PF10681.9 KPI38460.1 - 2e-86 288.9 0.0 2.4e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal F-box-like_2 PF13013.6 KPI38461.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain KNOX1 PF03790.13 KPI38461.1 - 0.071 12.9 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 KNOX1 domain Thioredoxin PF00085.20 KPI38462.1 - 4e-61 203.4 0.0 4.6e-31 106.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KPI38462.1 - 1.3e-19 70.8 0.4 8.8e-19 68.2 0.1 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KPI38462.1 - 6.8e-18 65.1 0.1 3.9e-08 33.7 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KPI38462.1 - 3.1e-14 53.0 0.0 1.1e-06 28.3 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KPI38462.1 - 1.4e-09 37.9 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KPI38462.1 - 1.5e-09 37.9 0.0 0.0009 19.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KPI38462.1 - 7.7e-09 35.8 0.0 0.003 17.8 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KPI38462.1 - 8.2e-07 28.8 0.2 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 KPI38462.1 - 5.8e-06 26.3 0.0 0.02 14.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KPI38462.1 - 0.00038 20.2 0.0 0.78 9.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 KPI38462.1 - 0.001 19.0 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein HyaE PF07449.11 KPI38462.1 - 0.0011 18.9 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 KPI38462.1 - 0.0036 17.5 3.8 3 8.0 0.0 4.2 3 2 1 4 4 4 1 Thioredoxin Glutaredoxin PF00462.24 KPI38462.1 - 0.024 14.9 0.9 7.5 6.9 0.0 2.9 2 2 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.6 KPI38462.1 - 0.2 12.0 0.0 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Transposase DDE domain PPR_2 PF13041.6 KPI38463.1 - 6e-54 180.0 6.9 4.1e-11 42.9 0.0 12.1 11 2 2 13 13 12 8 PPR repeat family PPR_3 PF13812.6 KPI38463.1 - 1.3e-33 114.9 3.9 0.0003 20.8 0.0 12.0 7 5 6 13 13 13 9 Pentatricopeptide repeat domain PPR PF01535.20 KPI38463.1 - 3.7e-33 111.4 14.5 0.00058 19.9 0.1 14.0 15 1 0 15 15 15 7 PPR repeat PPR_1 PF12854.7 KPI38463.1 - 4.6e-23 80.6 5.1 5.3e-06 26.0 0.1 11.0 10 1 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KPI38463.1 - 2.9e-19 69.3 13.0 3.7e-08 33.0 0.1 6.0 4 1 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 KPI38463.1 - 0.00039 20.3 0.7 0.012 15.5 0.1 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS Elong_Iki1 PF10483.9 KPI38463.1 - 0.0057 16.2 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF3368 PF11848.8 KPI38463.1 - 0.021 14.6 0.0 0.68 9.8 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) CysG_dimeriser PF10414.9 KPI38463.1 - 0.13 12.0 0.3 0.94 9.3 0.0 2.7 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region TPR_7 PF13176.6 KPI38463.1 - 2.2 8.5 7.6 2.6 8.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI38463.1 - 8.6 7.5 23.4 25 6.0 0.2 9.3 8 2 2 10 10 10 0 Tetratricopeptide repeat RRM_1 PF00076.22 KPI38464.1 - 4.6e-20 71.2 0.0 7.5e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BCDHK_Adom3 PF10436.9 KPI38465.1 - 8.4e-73 243.5 0.1 1.2e-72 243.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KPI38465.1 - 1.1e-09 38.8 0.0 2.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KPI38465.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E2_bind PF08825.10 KPI38465.1 - 0.088 13.0 0.2 0.41 10.8 0.0 2.3 3 1 0 3 3 3 0 E2 binding domain Pkinase PF00069.25 KPI38466.1 - 9.6e-51 172.7 0.0 1.8e-48 165.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI38466.1 - 4.1e-28 98.4 0.0 2.4e-27 95.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KPI38466.1 - 0.0015 17.7 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Sec_GG PF07549.14 KPI38466.1 - 0.033 13.7 0.5 0.086 12.4 0.5 1.7 1 0 0 1 1 1 0 SecD/SecF GG Motif Pkinase_fungal PF17667.1 KPI38466.1 - 0.034 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KPI38466.1 - 0.045 12.7 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KPI38466.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3328 PF11807.8 KPI38467.1 - 3.6e-48 164.2 3.3 4.3e-48 164.0 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RNA_pol_A_bac PF01000.26 KPI38469.1 - 4.4e-06 27.1 0.0 1e-05 25.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KPI38469.1 - 0.00011 21.5 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PhoH PF02562.16 KPI38470.1 - 0.031 13.7 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF3432 PF11914.8 KPI38470.1 - 0.81 10.0 12.8 0.28 11.4 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) tRNA_int_endo PF01974.17 KPI38471.1 - 1.5e-10 41.0 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF4385 PF14328.6 KPI38473.1 - 1.7e-50 170.9 0.1 2.8e-50 170.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) DUF3433 PF11915.8 KPI38474.1 - 3e-29 101.3 29.2 3e-16 59.6 3.4 4.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) GMC_oxred_N PF00732.19 KPI38475.1 - 1.1e-52 179.3 0.0 3.2e-50 171.2 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI38475.1 - 8.3e-27 94.5 0.0 1.4e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI38475.1 - 0.0001 21.5 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI38475.1 - 0.0022 17.1 0.0 0.78 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI38475.1 - 0.025 14.8 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI38475.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI38475.1 - 0.047 12.9 0.1 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI38475.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPI38475.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KPI38475.1 - 0.19 10.9 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KPI38475.1 - 0.2 10.3 0.1 0.89 8.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein ATP_bind_1 PF03029.17 KPI38477.1 - 2.8e-64 217.2 0.0 3.7e-63 213.5 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KPI38477.1 - 3.3e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KPI38477.1 - 0.0024 17.9 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPI38477.1 - 0.0096 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KPI38477.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KPI38477.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPI38477.1 - 0.012 16.0 0.0 0.037 14.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 KPI38477.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KPI38477.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KPI38477.1 - 0.02 15.3 0.1 0.05 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI38477.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KPI38477.1 - 0.021 15.3 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KPI38477.1 - 0.024 14.3 0.0 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPI38477.1 - 0.025 14.9 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KPI38477.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF463 PF04317.12 KPI38477.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 Thymidylate_kin PF02223.17 KPI38477.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.6 KPI38477.1 - 0.03 14.9 0.0 0.071 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KPI38477.1 - 0.064 12.7 0.0 0.66 9.4 0.0 2.3 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_16 PF13191.6 KPI38477.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KPI38477.1 - 0.093 12.6 0.1 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KPI38477.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KPI38477.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 KPI38477.1 - 0.14 11.9 0.0 0.8 9.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KPI38477.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DENN PF02141.21 KPI38478.1 - 3.5e-40 137.9 0.1 5.9e-40 137.2 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KPI38478.1 - 0.00012 22.8 0.1 0.00053 20.7 0.0 2.2 2 0 0 2 2 2 1 uDENN domain TRAF_BIRC3_bd PF16673.5 KPI38478.1 - 0.0045 16.8 2.9 0.45 10.3 0.7 3.0 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain IFT57 PF10498.9 KPI38478.1 - 0.011 14.7 5.5 0.028 13.4 5.5 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SMC_Nse1 PF07574.13 KPI38478.1 - 0.028 14.3 0.7 0.084 12.8 0.5 1.9 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex TMF_TATA_bd PF12325.8 KPI38478.1 - 0.096 12.9 11.1 0.72 10.1 3.8 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KPI38478.1 - 0.96 9.5 13.4 0.087 12.9 6.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KPI38478.1 - 1.2 9.3 16.0 1.5 8.9 7.1 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KPI38478.1 - 1.2 9.0 12.7 18 5.2 0.4 3.6 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 KPI38478.1 - 1.5 9.0 9.4 0.95 9.6 3.5 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 KPI38478.1 - 2.4 7.4 14.9 0.53 9.5 5.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Acetyltransf_10 PF13673.7 KPI38479.1 - 5.8e-08 32.7 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI38479.1 - 7.6e-08 32.7 0.0 2.9e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI38479.1 - 1.8e-07 31.4 0.0 4.7e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPI38479.1 - 8.7e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KPI38479.1 - 0.00095 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Cnd3 PF12719.7 KPI38480.1 - 4.7e-38 131.0 4.8 1.9e-37 129.0 0.4 3.1 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KPI38480.1 - 3.5e-09 36.1 9.0 0.021 15.1 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 KPI38480.1 - 1.6e-08 34.8 14.3 7.4e-05 23.1 2.0 4.6 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KPI38480.1 - 0.0016 18.9 10.8 0.54 10.8 0.2 6.1 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 KPI38480.1 - 0.005 16.9 0.6 1 9.4 0.2 3.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 adh_short PF00106.25 KPI38481.1 - 6.1e-14 51.9 0.2 3.3e-13 49.5 0.5 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI38481.1 - 4.9e-05 23.3 0.3 7.9e-05 22.6 0.1 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 KPI38481.1 - 0.0016 18.0 0.4 0.005 16.4 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KPI38481.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.15 KPI38481.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 KPI38481.1 - 0.14 12.8 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KPI38481.1 - 0.17 11.3 0.1 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_transf_15 PF01793.16 KPI38482.1 - 2.7e-62 210.9 13.7 3.9e-61 207.1 13.7 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SnoaL_2 PF12680.7 KPI38483.1 - 0.067 13.8 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Grg1 PF11034.8 KPI38484.1 - 1.6e-22 79.5 4.2 2e-22 79.2 4.2 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 HAD_2 PF13419.6 KPI38485.1 - 3.4e-25 89.1 0.0 4.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI38485.1 - 8.5e-13 49.1 0.0 5.1e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI38485.1 - 6.4e-09 35.8 0.0 7.6e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KPI38485.1 - 5.8e-05 23.6 0.0 7.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAND PF09110.11 KPI38485.1 - 0.025 15.3 0.0 0.061 14.1 0.0 1.6 1 0 0 1 1 1 0 HAND PGP_phosphatase PF09419.10 KPI38485.1 - 0.04 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.6 KPI38485.1 - 0.08 13.1 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 KPI38487.1 - 0.00028 21.1 0.0 1.7 9.0 0.0 3.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KPI38487.1 - 0.038 13.2 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Form-deh_trans PF09163.11 KPI38487.1 - 0.14 11.9 0.0 24 4.8 0.0 2.4 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane DNA_pol_B PF00136.21 KPI38488.1 - 7.3e-138 460.1 6.0 4.3e-119 398.2 5.2 2.1 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KPI38488.1 - 1.7e-24 86.6 0.4 3.3e-24 85.6 0.4 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KPI38488.1 - 2.9e-19 69.3 4.0 7.9e-19 67.9 4.0 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 KPI38488.1 - 0.00082 19.4 0.3 0.0058 16.6 0.3 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 KPI38488.1 - 0.0015 17.5 5.6 0.0034 16.3 0.1 2.7 3 1 0 3 3 3 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KPI38488.1 - 0.0045 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 KPI38488.1 - 0.005 16.7 6.4 0.088 12.7 0.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) NmrA PF05368.13 KPI38489.1 - 4.2e-17 62.5 0.9 5.8e-17 62.0 0.9 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI38489.1 - 2.9e-15 56.6 0.4 4e-15 56.2 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI38489.1 - 0.0049 16.4 0.1 0.076 12.5 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KPI38489.1 - 0.0058 16.1 2.2 0.021 14.3 0.9 2.2 1 1 1 2 2 2 1 short chain dehydrogenase YIEGIA PF14045.6 KPI38489.1 - 0.073 11.9 0.2 0.16 10.8 0.2 1.5 1 0 0 1 1 1 0 YIEGIA protein DUF2590 PF10761.9 KPI38489.1 - 0.081 13.1 0.2 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) p450 PF00067.22 KPI38490.1 - 1.1e-49 169.5 0.0 1.3e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.17 KPI38491.1 - 1e-40 140.2 0.0 1.3e-40 139.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 AftA_N PF12250.8 KPI38491.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal TRAPPC-Trs85 PF12739.7 KPI38492.1 - 2.4e-96 323.2 0.0 4e-96 322.5 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_3 PF07720.12 KPI38492.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI38492.1 - 0.024 14.7 2.0 0.042 14.0 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NUC173 PF08161.12 KPI38493.1 - 3.6e-74 248.9 1.2 3e-73 245.8 0.0 3.2 4 0 0 4 4 4 1 NUC173 domain HEAT PF02985.22 KPI38493.1 - 3.8e-05 23.6 1.7 0.048 13.9 0.1 4.3 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KPI38493.1 - 0.0014 19.0 2.1 0.099 13.0 0.2 4.4 3 1 1 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KPI38493.1 - 0.012 16.1 0.0 70 4.1 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HHA PF05321.11 KPI38493.1 - 0.013 15.8 0.0 13 6.2 0.0 3.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein Nipped-B_C PF12830.7 KPI38493.1 - 0.019 14.9 0.0 0.063 13.2 0.0 1.9 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus RsbRD_N PF14361.6 KPI38493.1 - 0.026 15.2 0.1 13 6.6 0.0 4.4 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain TFCD_C PF12612.8 KPI38493.1 - 0.47 10.3 4.3 7.7 6.3 0.1 4.4 4 1 0 5 5 5 0 Tubulin folding cofactor D C terminal Xpo1 PF08389.12 KPI38493.1 - 0.64 10.1 6.6 46 4.1 0.0 5.3 6 1 0 7 7 7 0 Exportin 1-like protein FAM219A PF15260.6 KPI38493.1 - 1.4 9.3 5.2 3.8 7.9 5.2 1.7 1 0 0 1 1 1 0 Protein family FAM219A DUF92 PF01940.16 KPI38495.1 - 3.4e-76 255.8 7.0 4.3e-76 255.4 7.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Cyclin_N PF00134.23 KPI38496.1 - 8.9e-11 41.6 1.9 2.5e-10 40.2 0.4 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain DUF726 PF05277.12 KPI38497.1 - 1.6e-124 415.3 2.0 2.2e-124 414.9 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PLDc PF00614.22 KPI38498.1 - 3.4e-17 61.8 1.6 3.2e-07 30.2 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KPI38498.1 - 9.7e-17 61.1 0.0 6.1e-07 29.4 0.0 4.0 3 1 0 3 3 3 3 PLD-like domain FliD_N PF02465.18 KPI38499.1 - 0.0027 18.4 7.5 0.018 15.7 1.9 2.4 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 N-terminus Homeodomain PF00046.29 KPI38500.1 - 1.6e-17 63.1 4.7 3.4e-17 62.0 4.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KPI38500.1 - 0.00029 20.7 1.2 0.0009 19.1 1.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain ArsB PF02040.15 KPI38501.1 - 3.4e-11 43.1 12.1 4.4e-06 26.3 5.4 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KPI38501.1 - 9.7e-11 41.4 6.8 9.7e-11 41.4 6.8 1.9 1 1 1 2 2 2 1 Citrate transporter YmcE_antitoxin PF15939.5 KPI38501.1 - 0.12 12.6 0.3 2.3 8.4 0.1 2.7 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system PrgI PF12666.7 KPI38501.1 - 1.4 9.6 0.0 1.4 9.6 0.0 4.4 4 2 0 4 4 4 0 PrgI family protein RRM_1 PF00076.22 KPI38502.1 - 3.6e-25 87.6 0.0 5.5e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPI38502.1 - 0.00019 21.4 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 KPI38502.1 - 0.032 14.4 0.0 0.32 11.1 0.0 2.6 3 1 0 3 3 3 0 RNA recognition motif UPF0113 PF03657.13 KPI38502.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 UPF0113 PUA domain Nup35_RRM_2 PF14605.6 KPI38502.1 - 0.1 12.6 0.0 14 5.8 0.0 2.6 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Med3 PF11593.8 KPI38502.1 - 1.1 8.4 8.6 1.4 8.0 8.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F1F0-ATPsyn_F PF10791.9 KPI38503.1 - 1.2e-38 131.5 0.2 1.3e-38 131.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KPI38503.1 - 2.7e-05 24.5 0.0 3.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ATP_bind_3 PF01171.20 KPI38504.1 - 4e-31 108.2 0.0 1.2e-29 103.4 0.0 2.3 1 1 0 1 1 1 1 PP-loop family SBP_bac_5 PF00496.22 KPI38504.1 - 0.077 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_S5_C PF03719.15 KPI38505.1 - 9.1e-20 69.9 0.0 1.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KPI38505.1 - 1.7e-16 59.9 0.0 3.5e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain RE_MjaI PF09568.10 KPI38505.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 MjaI restriction endonuclease Sin_N PF04801.13 KPI38506.1 - 1.8e-17 63.7 0.0 2.4e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Pantoate_ligase PF02569.15 KPI38508.1 - 1.1e-90 303.4 0.0 1.3e-90 303.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Chs7 PF12271.8 KPI38509.1 - 3.1e-118 394.3 18.9 3.7e-118 394.1 18.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4281 PF14108.6 KPI38509.1 - 0.011 16.2 6.0 0.011 16.2 6.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4281) An_peroxidase PF03098.15 KPI38510.1 - 9.2e-35 120.2 0.0 6.1e-25 87.8 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase UQ_con PF00179.26 KPI38510.1 - 1.4e-16 60.4 0.0 3.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme p450 PF00067.22 KPI38510.1 - 0.0024 16.7 0.0 0.0056 15.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 PIG-Y PF15159.6 KPI38511.1 - 1.7e-22 80.1 7.6 3.5e-22 79.1 7.6 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y ADH_N PF08240.12 KPI38512.1 - 6.3e-25 87.2 3.0 1.2e-24 86.3 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI38512.1 - 1.2e-16 60.8 0.0 4.6e-16 59.0 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI38512.1 - 0.00024 22.2 0.0 0.00044 21.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KPI38512.1 - 0.078 12.7 0.4 0.18 11.5 0.1 1.7 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KPI38512.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ETC_C1_NDUFA4 PF04800.12 KPI38512.1 - 0.16 12.3 0.3 1 9.7 0.1 2.1 2 0 0 2 2 2 0 ETC complex I subunit conserved region ThiF PF00899.21 KPI38512.1 - 0.16 11.3 0.4 0.26 10.6 0.4 1.2 1 0 0 1 1 1 0 ThiF family zf-C2H2_4 PF13894.6 KPI38513.1 - 1.8e-07 31.4 2.0 0.0038 17.9 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI38513.1 - 0.00028 21.2 2.8 0.0086 16.5 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF3827 PF12877.7 KPI38513.1 - 0.022 13.2 0.6 0.038 12.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) zf-C2H2_11 PF16622.5 KPI38513.1 - 0.097 12.4 2.3 0.18 11.6 2.3 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type ETC_C1_NDUFA4 PF04800.12 KPI38515.1 - 1.4e-35 121.4 0.3 2.3e-35 120.7 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region 2OG-FeII_Oxy_3 PF13640.6 KPI38516.1 - 3.9e-09 37.3 0.0 1e-08 35.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_pol_B_exo1 PF03104.19 KPI38518.1 - 1.4e-43 149.3 0.0 2e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Glu_cys_ligase PF04262.14 KPI38518.1 - 0.099 11.2 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase Actin PF00022.19 KPI38519.1 - 1.9e-49 168.4 0.0 1.8e-27 96.0 0.0 2.2 2 0 0 2 2 2 2 Actin DNMT1-RFD PF12047.8 KPI38520.1 - 0.0044 17.1 0.5 0.0096 16.0 0.0 1.8 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain STATa_Ig PF18214.1 KPI38520.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain HTH_32 PF13565.6 KPI38520.1 - 0.054 14.1 2.0 0.64 10.7 0.0 3.2 3 1 0 3 3 3 0 Homeodomain-like domain THOC2_N PF16134.5 KPI38520.1 - 0.34 9.5 6.4 0.69 8.5 6.4 1.4 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF913 PF06025.12 KPI38520.1 - 1.4 7.8 12.5 0.57 9.1 4.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CobT PF06213.12 KPI38520.1 - 2.6 7.4 24.1 0.21 10.9 15.9 2.3 2 1 0 2 2 2 0 Cobalamin biosynthesis protein CobT GDPD PF03009.17 KPI38521.1 - 6e-68 229.4 0.0 1.1e-67 228.5 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KPI38521.1 - 2.6e-29 101.7 0.0 6.8e-09 36.2 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI38521.1 - 2.2e-28 98.2 2.3 4.4e-08 33.5 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI38521.1 - 6.7e-23 80.5 0.2 4.4e-07 30.1 0.1 5.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI38521.1 - 3.5e-19 66.9 2.7 0.0012 19.2 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat SPX PF03105.19 KPI38521.1 - 1.5e-18 67.9 12.0 2e-11 44.5 0.1 3.7 2 1 2 4 4 4 3 SPX domain Ank PF00023.30 KPI38521.1 - 1.3e-16 60.2 1.9 0.0005 20.4 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat DUF1978 PF09321.10 KPI38521.1 - 0.072 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) SKN1 PF03935.15 KPI38523.1 - 5e-214 711.3 7.4 5.8e-214 711.1 7.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_S10 PF00450.22 KPI38525.1 - 9.2e-113 377.8 0.0 1.2e-112 377.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase NMN_transporter PF04973.12 KPI38525.1 - 0.1 12.5 1.2 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter Radical_SAM PF04055.21 KPI38526.1 - 3e-09 37.5 0.0 4.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KPI38526.1 - 1.8e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KPI38526.1 - 0.017 15.3 0.0 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain XAF1_C PF18608.1 KPI38526.1 - 0.073 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain zf-C2H2_4 PF13894.6 KPI38527.1 - 1.8e-12 47.0 25.4 0.076 13.9 0.8 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI38527.1 - 1e-08 35.1 25.7 0.009 16.4 0.4 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI38527.1 - 1.9e-05 24.9 23.1 0.62 10.6 0.1 6.5 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPI38527.1 - 7.9e-05 22.8 23.5 0.47 10.8 0.1 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KPI38527.1 - 0.014 15.8 22.4 0.88 9.9 1.7 4.4 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) IBR PF01485.21 KPI38527.1 - 0.02 15.1 22.6 0.049 13.9 1.3 4.4 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain GAGA PF09237.11 KPI38527.1 - 0.057 13.2 2.4 12 5.7 0.6 3.4 3 0 0 3 3 3 0 GAGA factor FOXP-CC PF16159.5 KPI38527.1 - 0.23 12.1 19.3 0.68 10.6 0.3 5.2 4 2 2 6 6 6 0 FOXP coiled-coil domain zf-met PF12874.7 KPI38527.1 - 4.5 7.8 0.0 4.5 7.8 0.0 6.4 7 1 0 7 7 7 0 Zinc-finger of C2H2 type Glyco_tranf_2_3 PF13641.6 KPI38528.1 - 6.1e-21 75.4 0.0 8.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KPI38528.1 - 0.0066 15.9 0.0 0.057 12.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 adh_short_C2 PF13561.6 KPI38529.1 - 5.2e-57 193.1 0.1 7.2e-57 192.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38529.1 - 1.8e-43 148.3 0.1 3.2e-43 147.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KPI38529.1 - 6.1e-07 29.1 0.1 2e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI38529.1 - 0.00012 22.0 0.1 0.00025 21.0 0.1 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI38529.1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Urocanase PF01175.18 KPI38529.1 - 0.00081 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain 3HCDH_N PF02737.18 KPI38529.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KPI38529.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF3605 PF12239.8 KPI38529.1 - 0.03 14.6 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) UDPG_MGDP_dh_N PF03721.14 KPI38529.1 - 0.056 13.0 0.3 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KPI38529.1 - 0.061 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPI38529.1 - 0.081 13.4 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 KPI38529.1 - 0.096 12.7 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2OG-FeII_Oxy PF03171.20 KPI38530.1 - 2.2e-15 56.9 0.0 4.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPI38530.1 - 1.4e-13 51.6 0.0 2.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DNA_pol3_delta2 PF13177.6 KPI38531.1 - 1e-10 41.7 0.0 2.1e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KPI38531.1 - 2.5e-07 31.2 0.4 1e-06 29.2 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KPI38531.1 - 3.2e-05 24.2 0.1 0.00014 22.2 0.0 2.1 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KPI38531.1 - 0.0034 17.6 0.6 0.016 15.5 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI38531.1 - 0.0098 16.3 0.5 0.057 13.8 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KPI38531.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KPI38531.1 - 0.096 12.4 0.2 0.26 11.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain Prenyltransf PF01255.19 KPI38531.1 - 0.27 10.7 1.1 0.72 9.3 1.1 1.7 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase 2OG-FeII_Oxy PF03171.20 KPI38532.1 - 2.7e-22 79.1 0.0 5e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPI38532.1 - 2e-21 76.9 0.0 4.7e-21 75.7 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4743 PF15916.5 KPI38534.1 - 2.6e-13 50.0 0.0 3.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KPI38534.1 - 3.9e-11 43.1 0.0 7.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PTCB-BRCT PF12738.7 KPI38535.1 - 6.5e-41 138.1 1.9 4.8e-19 68.1 0.0 4.7 4 1 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KPI38535.1 - 1.2e-27 96.1 0.0 2.3e-08 34.3 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPI38535.1 - 5e-16 58.9 0.0 0.0022 18.3 0.0 4.5 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KPI38535.1 - 7e-05 23.0 0.6 0.23 11.8 0.2 3.3 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KPI38535.1 - 0.0007 19.4 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KPI38535.1 - 0.0035 17.4 0.0 0.13 12.3 0.1 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Amidohydro_2 PF04909.14 KPI38536.1 - 3.1e-15 56.7 0.2 2.1e-12 47.4 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase DUF2183 PF09949.9 KPI38537.1 - 5.7e-33 113.2 0.0 1.4e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 KPI38537.1 - 0.0016 18.7 1.1 0.014 15.6 0.1 2.8 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain MVL PF12151.8 KPI38537.1 - 0.04 13.8 0.5 0.11 12.3 0.5 1.8 1 0 0 1 1 1 0 Mannan-binding protein Fungal_trans_2 PF11951.8 KPI38538.1 - 4.5e-08 32.3 1.3 7.4e-08 31.6 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain S6PP PF05116.13 KPI38538.1 - 0.059 12.9 0.3 8.2 5.9 0.1 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Fcf1 PF04900.12 KPI38539.1 - 2.3e-13 50.4 0.2 3.7e-12 46.5 0.2 2.6 1 1 0 1 1 1 1 Fcf1 DEAD PF00270.29 KPI38540.1 - 8.3e-43 146.2 0.2 1.3e-42 145.5 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI38540.1 - 1.4e-21 76.9 0.0 3.4e-20 72.4 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPI38540.1 - 1.3e-19 70.2 0.0 3.2e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPI38540.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KPI38540.1 - 0.035 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase bZIP_1 PF00170.21 KPI38541.1 - 1.5e-07 31.4 9.9 3e-07 30.4 6.3 2.3 1 1 1 2 2 2 1 bZIP transcription factor ASD2 PF08687.11 KPI38541.1 - 9.8e-06 25.3 1.4 1.1e-05 25.1 1.4 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Yuri_gagarin PF15934.5 KPI38541.1 - 0.00076 19.4 4.9 0.00098 19.0 4.9 1.1 1 0 0 1 1 1 1 Yuri gagarin DUF4094 PF13334.6 KPI38541.1 - 0.0012 19.2 2.0 0.002 18.5 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) CEP63 PF17045.5 KPI38541.1 - 0.0015 18.5 2.8 0.002 18.1 2.8 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa DUF4618 PF15397.6 KPI38541.1 - 0.0018 17.7 1.3 0.0024 17.3 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) bZIP_2 PF07716.15 KPI38541.1 - 0.0033 17.5 6.1 0.0033 17.5 6.1 2.9 2 1 1 3 3 3 1 Basic region leucine zipper Pox_A_type_inc PF04508.12 KPI38541.1 - 0.0045 16.8 0.6 0.062 13.2 0.2 2.6 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat APG6_N PF17675.1 KPI38541.1 - 0.005 17.4 5.2 0.0076 16.8 5.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region EzrA PF06160.12 KPI38541.1 - 0.0071 14.6 1.4 0.009 14.2 1.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF812 PF05667.11 KPI38541.1 - 0.017 14.1 3.0 0.019 13.9 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SYCE1 PF15233.6 KPI38541.1 - 0.02 15.0 4.5 0.03 14.4 4.5 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 ABC_tran_CTD PF16326.5 KPI38541.1 - 0.021 15.1 1.1 0.042 14.1 1.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TMF_TATA_bd PF12325.8 KPI38541.1 - 0.029 14.6 4.9 0.06 13.6 4.8 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 KPI38541.1 - 0.032 14.6 3.3 0.064 13.6 3.1 1.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dad4 PF08650.10 KPI38541.1 - 0.042 13.8 0.2 0.08 12.9 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad4 WD40_alt PF14077.6 KPI38541.1 - 0.055 13.3 0.2 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif Baculo_PEP_C PF04513.12 KPI38541.1 - 0.088 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 KPI38541.1 - 0.095 12.4 5.7 0.27 10.9 5.5 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Macoilin PF09726.9 KPI38541.1 - 0.12 10.9 6.0 0.14 10.7 6.0 1.0 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 KPI38541.1 - 0.12 12.4 3.7 0.17 12.0 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KPI38541.1 - 0.17 10.9 6.4 0.22 10.6 6.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PI3K_P85_iSH2 PF16454.5 KPI38541.1 - 0.23 11.1 6.3 0.33 10.5 6.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Jnk-SapK_ap_N PF09744.9 KPI38541.1 - 0.24 11.6 10.7 0.34 11.1 10.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF5446 PF17522.2 KPI38541.1 - 0.34 11.1 1.5 5.2 7.3 1.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Csm1_N PF18504.1 KPI38541.1 - 0.63 10.4 3.6 3.8 7.9 1.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain GvpL_GvpF PF06386.11 KPI38541.1 - 2.1 8.2 6.5 3.5 7.5 6.4 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_Maf PF03131.17 KPI38541.1 - 2.8 8.5 16.2 0.1 13.1 8.2 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor FlxA PF14282.6 KPI38541.1 - 5.8 7.0 7.2 0.54 10.3 1.9 2.0 2 1 0 2 2 1 0 FlxA-like protein PH PF00169.29 KPI38542.1 - 4.5e-22 78.6 0.1 6.3e-10 39.5 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 KPI38542.1 - 9.9e-08 32.4 0.0 0.00064 20.1 0.0 3.4 2 2 1 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 KPI38542.1 - 3.6e-07 30.6 0.1 0.068 13.5 0.0 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain Ribosomal_L14 PF00238.19 KPI38543.1 - 9.4e-34 116.1 0.0 1.1e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Thymidylate_kin PF02223.17 KPI38544.1 - 0.13 12.0 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Thymidylate kinase p450 PF00067.22 KPI38545.1 - 2.5e-49 168.3 0.0 3.4e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RL10P_insert PF17777.1 KPI38547.1 - 1.1e-23 83.0 0.0 1.7e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KPI38547.1 - 7.4e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 p450 PF00067.22 KPI38548.1 - 6.6e-12 44.9 0.0 8.5e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ran_BP1 PF00638.18 KPI38549.1 - 7.2e-27 94.1 1.3 1.2e-20 74.0 0.0 2.7 1 1 1 2 2 2 2 RanBP1 domain CDC27 PF09507.10 KPI38549.1 - 0.011 15.2 23.6 0.013 14.9 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VID27_PH PF17747.1 KPI38549.1 - 0.024 14.9 0.0 0.047 14.0 0.0 1.5 1 1 0 1 1 1 0 VID27 PH-like domain DNA_pol_phi PF04931.13 KPI38549.1 - 0.96 7.5 13.8 1.3 7.0 13.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 KPI38549.1 - 6.2 6.3 16.7 8.5 5.9 16.7 1.3 1 0 0 1 1 1 0 PPP4R2 Pneumo_att_G PF05539.11 KPI38549.1 - 9.8 5.7 10.3 12 5.4 10.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G WD40 PF00400.32 KPI38550.1 - 6.8e-39 131.2 17.4 1.2e-05 26.0 1.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38550.1 - 2.7e-15 56.4 0.0 0.00046 20.4 0.1 5.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI38550.1 - 4.9e-05 23.3 0.0 0.2 11.5 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KPI38550.1 - 0.01 15.2 0.0 0.3 10.4 0.0 2.7 1 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KPI38550.1 - 0.014 14.4 0.2 18 4.2 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein bZIP_1 PF00170.21 KPI38552.1 - 6.7e-09 35.7 7.0 1.3e-08 34.8 7.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Imm32 PF15566.6 KPI38552.1 - 0.19 11.6 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 32 bZIP_2 PF07716.15 KPI38552.1 - 0.34 11.0 10.2 20 5.4 10.2 2.2 1 1 0 1 1 1 0 Basic region leucine zipper EF-hand_1 PF00036.32 KPI38553.1 - 1.5e-32 108.7 12.4 3.5e-08 32.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KPI38553.1 - 1.1e-26 93.0 3.7 8.2e-15 55.0 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KPI38553.1 - 3.9e-26 88.7 5.9 3.7e-09 35.8 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KPI38553.1 - 5.1e-22 77.5 6.7 6.6e-13 48.3 0.5 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KPI38553.1 - 2.2e-20 71.2 14.3 1.1e-06 27.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KPI38553.1 - 1.5e-12 47.7 0.2 2.8e-09 37.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 KPI38553.1 - 8.1e-05 22.6 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 KPI38553.1 - 0.00045 20.5 0.2 0.31 11.4 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 KPI38553.1 - 0.00059 20.7 0.0 0.68 10.8 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KPI38553.1 - 0.00085 19.6 0.1 0.84 10.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KPI38553.1 - 0.00085 19.2 2.2 0.0066 16.4 0.2 2.3 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KPI38553.1 - 0.0042 17.0 0.4 9.1 6.2 0.2 3.1 1 1 2 3 3 3 2 Caleosin related protein Toprim_2 PF13155.6 KPI38553.1 - 0.0056 17.1 0.6 1.1 9.7 0.1 2.5 1 1 1 2 2 2 1 Toprim-like FGAR-AT_linker PF18072.1 KPI38553.1 - 0.0073 16.8 0.0 1.6 9.4 0.0 2.6 2 1 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain RNA_pol_Rpb4 PF03874.16 KPI38553.1 - 0.0076 16.6 1.2 3.1 8.2 0.2 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 Phage_TAC_12 PF12363.8 KPI38553.1 - 0.12 12.8 0.6 5.1 7.6 0.1 2.5 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC SurA_N_2 PF13623.6 KPI38553.1 - 0.13 12.2 0.2 20 5.1 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain DUF1296 PF06972.11 KPI38553.1 - 0.26 11.5 2.1 0.77 9.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) DUF5132 PF17195.4 KPI38553.1 - 0.53 10.4 1.6 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Mito_carr PF00153.27 KPI38554.1 - 1.4e-65 217.3 5.1 1.5e-22 79.3 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KPI38554.1 - 1.8e-22 79.6 6.8 3e-13 50.0 3.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KPI38554.1 - 2.9e-19 67.1 5.5 1.3e-06 27.5 1.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KPI38554.1 - 7.6e-18 63.1 6.4 2.1e-06 27.0 1.4 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KPI38554.1 - 1.6e-17 61.9 8.6 7.7e-05 22.3 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KPI38554.1 - 6e-14 51.6 6.2 4.8e-06 26.3 0.3 3.3 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KPI38554.1 - 5.6e-08 33.1 0.4 0.00043 20.6 0.2 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KPI38554.1 - 0.0015 18.4 2.4 0.13 12.3 0.5 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Serine_protease PF18405.1 KPI38554.1 - 0.016 14.4 0.9 1.2 8.2 0.2 3.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EF-hand_10 PF14788.6 KPI38554.1 - 0.041 13.7 4.3 1.7 8.6 0.1 3.8 3 1 1 4 4 4 0 EF hand Ribosomal_L3 PF00297.22 KPI38555.1 - 3.9e-178 592.1 9.0 4.7e-178 591.8 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 GGACT PF06094.12 KPI38556.1 - 1.1e-06 29.2 0.0 1.5e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KPI38556.1 - 3e-06 27.6 0.0 7.5e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family adh_short PF00106.25 KPI38557.1 - 1.4e-23 83.4 0.0 9e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38557.1 - 4.7e-17 62.3 0.0 6.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38557.1 - 1.2e-05 25.3 0.2 2.7e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KPI38557.1 - 4e-05 23.6 0.2 0.00023 21.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KPI38557.1 - 0.0012 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KPI38557.1 - 0.025 14.3 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HMG_CoA_synt_C PF08540.10 KPI38558.1 - 1.6e-90 303.5 0.3 2.2e-90 303.1 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KPI38558.1 - 2.1e-44 151.4 0.1 3.3e-44 150.8 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3783 PF12646.7 KPI38558.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Mito_carr PF00153.27 KPI38559.1 - 3.7e-29 100.5 1.7 3.5e-19 68.5 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Rick_17kDa_Anti PF05433.15 KPI38560.1 - 0.00016 21.5 10.7 0.00016 21.5 10.7 2.4 3 0 0 3 3 3 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KPI38560.1 - 0.018 15.1 9.4 0.057 13.4 9.4 2.0 1 0 0 1 1 1 0 Glycine zipper Transgly_assoc PF04226.13 KPI38560.1 - 1.5 9.2 11.6 3.7 7.9 11.6 1.7 1 0 0 1 1 1 0 Transglycosylase associated protein Peptidase_S10 PF00450.22 KPI38561.1 - 7.2e-62 210.1 0.2 4.5e-59 200.9 0.2 2.5 1 1 0 1 1 1 1 Serine carboxypeptidase Mhr1 PF12829.7 KPI38562.1 - 9.2e-11 41.7 0.5 2.4e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Myc_N PF01056.18 KPI38562.1 - 1.3 8.8 7.4 2.4 8.0 7.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF302 PF03625.14 KPI38563.1 - 5.1e-07 29.5 0.0 8.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 p450 PF00067.22 KPI38564.1 - 1.3e-54 185.8 0.0 4.7e-45 154.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF4267 PF14087.6 KPI38565.1 - 1.9e-09 37.6 3.0 2.4e-09 37.2 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) BNR_3 PF13859.6 KPI38565.1 - 0.099 11.9 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 BNR repeat-like domain PGAP1 PF07819.13 KPI38566.1 - 4.1e-06 26.7 1.4 0.00019 21.2 0.3 2.4 2 1 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KPI38566.1 - 4.3e-06 26.4 0.0 1.2e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KPI38566.1 - 2.4e-05 25.0 0.1 3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI38566.1 - 0.00054 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KPI38566.1 - 0.0024 17.3 0.1 0.32 10.3 0.0 2.5 2 1 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KPI38566.1 - 0.013 15.2 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KPI38566.1 - 0.022 14.6 0.1 0.039 13.8 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KPI38566.1 - 0.035 13.6 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KPI38566.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KPI38566.1 - 0.094 12.8 0.1 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain GATase PF00117.28 KPI38567.1 - 9.4e-12 45.1 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C12 PF01088.21 KPI38568.1 - 4e-69 232.6 0.0 5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KPI38568.1 - 1.9e-09 37.2 0.0 4.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases WD40 PF00400.32 KPI38569.1 - 1.3e-17 63.8 25.5 0.0051 17.6 0.0 9.1 12 0 0 12 12 12 5 WD domain, G-beta repeat PD40 PF07676.12 KPI38569.1 - 0.006 16.5 0.0 1.4 9.0 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DAP10 PF07213.11 KPI38570.1 - 0.0012 18.7 0.2 0.0012 18.7 0.2 2.0 2 0 0 2 2 2 1 DAP10 membrane protein EphA2_TM PF14575.6 KPI38570.1 - 0.0031 18.3 0.0 0.0072 17.2 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SH3_1 PF00018.28 KPI38570.1 - 0.0078 15.8 0.3 0.028 14.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain DUF4690 PF15756.5 KPI38570.1 - 0.011 16.3 1.9 0.029 15.0 1.9 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage TMEM51 PF15345.6 KPI38570.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Syndecan PF01034.20 KPI38570.1 - 0.025 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.12 KPI38570.1 - 0.096 12.3 0.5 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family SH3_9 PF14604.6 KPI38570.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KPI38571.1 - 5.2e-06 26.0 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI38571.1 - 0.015 15.1 1.4 0.018 14.9 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain SH3_16 PF18348.1 KPI38571.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Dak1 PF02733.17 KPI38573.1 - 6.8e-12 44.9 0.0 1.7e-07 30.4 0.0 3.2 2 1 1 3 3 3 3 Dak1 domain zf-C2H2_assoc3 PF16637.5 KPI38574.1 - 0.053 13.7 0.7 0.13 12.5 0.7 1.6 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz GRIP PF01465.20 KPI38575.1 - 2.6e-17 62.4 0.1 6.1e-17 61.3 0.1 1.7 1 0 0 1 1 1 1 GRIP domain YL1_C PF08265.11 KPI38575.1 - 3e-13 49.3 1.1 5.4e-13 48.4 1.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GAS PF13851.6 KPI38575.1 - 2.3e-05 23.9 139.8 0.0033 16.8 18.0 9.2 3 2 6 9 9 9 5 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KPI38575.1 - 0.00057 19.9 13.7 0.00057 19.9 13.7 9.5 4 2 6 10 10 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 KPI38575.1 - 0.001 17.0 6.5 0.001 17.0 6.5 4.0 3 1 1 4 4 4 3 Myosin tail CCDC144C PF14915.6 KPI38575.1 - 0.0021 17.2 18.2 0.0021 17.2 18.2 6.8 3 2 3 6 6 4 1 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 KPI38575.1 - 0.0027 17.2 1.2 0.0027 17.2 1.2 7.9 3 2 3 7 7 7 2 Golgin subfamily A member 5 CALCOCO1 PF07888.11 KPI38575.1 - 0.0033 16.4 33.5 0.0033 16.4 33.5 5.7 3 1 3 6 6 6 4 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 KPI38575.1 - 0.005 17.1 7.9 0.005 17.1 7.9 10.9 4 3 7 11 11 10 3 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 KPI38575.1 - 0.0057 16.9 11.8 0.0057 16.9 11.8 11.5 4 3 7 12 12 12 2 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 KPI38575.1 - 0.0058 16.5 3.6 0.0058 16.5 3.6 10.9 3 2 5 10 10 9 4 Phage minor structural protein GP20 GIT_CC PF16559.5 KPI38575.1 - 0.014 15.3 1.0 0.014 15.3 1.0 9.7 10 2 3 13 13 12 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 KPI38575.1 - 0.017 15.6 0.3 0.017 15.6 0.3 11.1 3 2 7 10 10 10 0 Apg6 coiled-coil region Fez1 PF06818.15 KPI38575.1 - 0.04 14.4 143.1 0.33 11.4 18.7 7.9 3 2 5 8 8 8 0 Fez1 TPR_MLP1_2 PF07926.12 KPI38575.1 - 2.3 8.3 163.0 0.22 11.6 16.6 10.5 3 2 6 9 9 9 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KPI38575.1 - 2.4 7.6 154.3 1.9 8.0 2.8 8.3 3 2 5 8 8 8 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 KPI38575.1 - 2.6 6.8 151.5 0.16 10.8 24.7 8.6 3 2 4 8 8 8 0 Spc7 kinetochore protein DOT1 PF08123.13 KPI38576.1 - 2.7e-71 239.3 0.0 3.8e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 FAM176 PF14851.6 KPI38576.1 - 0.053 13.2 3.7 0.1 12.2 3.7 1.4 1 0 0 1 1 1 0 FAM176 family PGBA_C PF15437.6 KPI38576.1 - 0.068 13.5 1.1 0.15 12.4 1.1 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal LSM PF01423.22 KPI38578.1 - 1.1e-14 53.8 0.0 1.6e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Snf7 PF03357.21 KPI38579.1 - 2.7e-24 85.7 18.5 2.7e-24 85.7 18.5 2.1 1 1 1 2 2 2 1 Snf7 Hemerythrin PF01814.23 KPI38580.1 - 1.8e-12 48.0 2.7 2.2e-12 47.7 2.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fungal_trans PF04082.18 KPI38581.1 - 8.7e-06 25.0 0.8 2.3e-05 23.6 0.5 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI38581.1 - 0.0001 22.3 9.1 0.00024 21.2 9.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMA-1 PF02430.15 KPI38581.1 - 0.0054 15.7 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Apical membrane antigen 1 TFCD_C PF12612.8 KPI38582.1 - 3.4e-17 62.9 0.0 1.6e-16 60.7 0.0 2.3 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal IFRD PF05004.13 KPI38582.1 - 0.0022 17.2 2.3 1 8.4 0.1 2.7 3 0 0 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KPI38582.1 - 0.065 13.5 13.4 0.32 11.4 0.0 6.8 8 0 0 8 8 8 0 HEAT repeat Vac14_Fab1_bd PF12755.7 KPI38582.1 - 0.12 13.0 0.1 2.5 8.7 0.0 3.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region TetR_C_15 PF17918.1 KPI38582.1 - 9.8 7.0 9.4 32 5.4 3.1 4.0 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain WD40_alt PF14077.6 KPI38583.1 - 0.063 13.1 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif Osmo_CC PF08946.10 KPI38583.1 - 0.1 12.9 1.0 2.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Pkinase PF00069.25 KPI38584.1 - 1.3e-59 201.7 0.0 1.8e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI38584.1 - 7.7e-36 123.7 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KPI38584.1 - 2.4e-13 50.5 0.6 8.2e-13 48.8 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KPI38584.1 - 0.0057 16.3 0.2 0.069 12.8 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KPI38584.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TFIIA PF03153.13 KPI38584.1 - 2 8.3 30.4 3 7.7 30.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SnoaL_2 PF12680.7 KPI38585.1 - 7.1e-08 33.0 0.1 9.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain RNA_pol PF00940.19 KPI38587.1 - 4.6e-183 608.8 0.0 5.4e-183 608.5 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase PAXNEB PF05625.11 KPI38588.1 - 4e-98 329.0 0.0 4.5e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Zn_clus PF00172.18 KPI38589.1 - 4.9e-06 26.6 14.9 6.8e-06 26.1 14.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apq12 PF12716.7 KPI38590.1 - 2.2e-12 46.7 7.3 5.4e-12 45.5 7.3 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF4014 PF13198.6 KPI38590.1 - 0.091 13.2 0.3 0.16 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) FMO-like PF00743.19 KPI38591.1 - 3.5e-16 58.7 2.5 2.3e-12 46.1 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI38591.1 - 4.1e-14 52.5 0.0 4.7e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI38591.1 - 1.2e-12 47.7 2.3 1.7e-09 37.4 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI38591.1 - 5.4e-07 29.7 0.0 2.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI38591.1 - 1.3e-06 28.3 1.2 0.0001 22.0 1.2 3.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPI38591.1 - 5.6e-05 22.4 0.1 0.0013 17.9 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI38591.1 - 0.00017 21.6 0.4 0.068 13.2 0.0 3.8 4 1 1 5 5 5 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPI38591.1 - 0.00033 19.9 0.5 0.00057 19.1 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KPI38591.1 - 0.001 19.5 0.4 0.75 10.3 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KPI38591.1 - 0.0031 16.8 0.0 0.048 12.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 KPI38591.1 - 0.01 15.9 0.0 0.12 12.4 0.0 2.4 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KPI38591.1 - 0.015 15.9 0.0 9.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI38591.1 - 0.026 13.6 0.0 0.11 11.6 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPI38591.1 - 0.031 13.5 0.4 0.45 9.7 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KPI38591.1 - 0.055 12.2 0.3 0.62 8.7 0.4 2.2 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KPI38591.1 - 0.082 12.3 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1190 PF06693.11 KPI38592.1 - 0.049 14.0 4.0 0.065 13.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Tis11B_N PF04553.12 KPI38592.1 - 0.24 12.0 3.5 0.27 11.8 2.4 1.7 1 1 0 1 1 1 0 Tis11B like protein, N terminus Cyclin PF08613.11 KPI38593.1 - 6.2e-11 42.9 0.0 9.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KPI38593.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 KPI38594.1 - 4.6e-52 177.1 0.4 5.6e-52 176.8 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI38594.1 - 2.1e-21 76.3 0.8 5.3e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KPI38594.1 - 2.2e-20 72.9 0.0 5.4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 KPI38594.1 - 4e-06 26.3 4.7 0.00038 19.8 0.5 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI38594.1 - 2.1e-05 24.1 2.4 0.00024 20.6 0.3 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI38594.1 - 4.1e-05 23.7 0.5 0.049 13.9 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPI38594.1 - 6.9e-05 22.1 1.0 0.0046 16.1 1.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPI38594.1 - 8.2e-05 22.0 0.5 0.3 10.3 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain 3HCDH_N PF02737.18 KPI38594.1 - 0.0033 17.3 0.2 0.64 9.9 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KPI38594.1 - 0.021 13.9 3.2 0.025 13.7 0.8 2.2 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 KPI38594.1 - 0.027 14.9 0.3 0.55 10.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KPI38594.1 - 0.031 13.6 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPI38594.1 - 0.07 11.8 2.4 5.1 5.7 0.1 2.5 2 1 1 3 3 3 0 HI0933-like protein XdhC_C PF13478.6 KPI38594.1 - 0.1 13.1 0.1 3.5 8.2 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain LRR_9 PF14580.6 KPI38595.1 - 1.1e-56 191.1 0.5 1.7e-56 190.5 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KPI38595.1 - 1.6e-06 27.8 2.2 1.6e-06 27.8 2.2 2.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 KPI38595.1 - 2.6e-05 24.5 13.4 0.00018 21.8 3.4 3.7 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) Nop PF01798.18 KPI38595.1 - 0.013 15.0 1.2 2.7 7.4 0.3 2.1 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin LRR_6 PF13516.6 KPI38595.1 - 0.022 14.8 3.8 21 5.5 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Aminotran_1_2 PF00155.21 KPI38596.1 - 6.9e-57 193.3 0.0 1.2e-56 192.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI38596.1 - 0.00036 19.6 0.0 0.00066 18.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KPI38596.1 - 0.13 11.0 0.0 0.25 10.0 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 KPI38598.1 - 7.2e-38 130.4 0.0 1.5e-37 129.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI38598.1 - 2.6e-25 89.2 0.0 7.5e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI38598.1 - 0.026 13.3 0.0 0.053 12.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RE_AlwI PF09491.10 KPI38598.1 - 0.23 10.2 0.1 0.34 9.6 0.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease adh_short PF00106.25 KPI38600.1 - 2.2e-51 174.1 0.1 2.9e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38600.1 - 3.1e-38 131.7 0.0 3.7e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38600.1 - 1.3e-15 57.7 0.0 2.1e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KPI38600.1 - 0.00018 21.8 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KPI38600.1 - 0.0012 18.0 0.2 0.0043 16.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI38600.1 - 0.028 13.9 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cyanate_lyase PF02560.14 KPI38601.1 - 4.3e-30 103.4 0.0 6.5e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 KPI38601.1 - 0.0055 16.7 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HP0268 PF18618.1 KPI38601.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 HP0268 zf-C3HC4_3 PF13920.6 KPI38602.1 - 0.23 11.4 3.7 0.43 10.5 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI38602.1 - 2 8.8 5.3 3.9 7.9 5.3 1.5 1 0 0 1 1 1 0 Ring finger domain CCDC50_N PF15295.6 KPI38602.1 - 5.4 7.2 18.9 5.2 7.2 4.3 3.2 2 1 0 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus TPR_1 PF00515.28 KPI38603.1 - 5.4e-53 174.8 30.3 5.1e-08 32.4 0.1 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KPI38603.1 - 7.7e-46 150.5 24.1 7.2e-06 25.7 0.0 10.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 KPI38603.1 - 5.3e-35 116.7 18.6 7.8e-07 28.8 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KPI38603.1 - 3.9e-29 101.0 7.3 3.2e-06 27.7 0.3 6.5 4 2 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KPI38603.1 - 4.8e-24 84.6 15.7 1.4e-05 25.5 0.1 7.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KPI38603.1 - 2.4e-22 79.0 22.0 6.8e-05 23.1 1.2 8.2 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KPI38603.1 - 4.8e-22 76.8 13.4 0.00011 22.7 0.1 8.3 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI38603.1 - 1.5e-21 75.8 30.3 2e-05 24.2 0.1 9.5 5 3 4 9 9 9 6 TPR repeat TPR_17 PF13431.6 KPI38603.1 - 5.3e-21 73.4 21.7 0.00037 20.7 0.1 10.0 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 KPI38603.1 - 8.6e-18 63.7 18.5 0.032 14.9 0.7 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KPI38603.1 - 9.2e-17 59.8 13.8 0.046 13.8 0.0 9.2 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KPI38603.1 - 2.4e-14 53.2 8.4 0.00069 19.7 0.1 6.4 4 2 3 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI38603.1 - 4.1e-11 43.0 11.3 9.4e-07 29.0 1.5 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KPI38603.1 - 4.7e-07 29.3 13.9 0.00054 19.3 1.9 5.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_21 PF09976.9 KPI38603.1 - 1.8e-06 27.8 7.7 0.14 11.8 0.0 4.5 4 2 1 5 5 5 3 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KPI38603.1 - 0.00072 19.6 0.3 1 9.5 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KPI38603.1 - 0.0011 19.4 9.8 0.39 11.2 0.2 3.8 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 KPI38603.1 - 0.0013 18.5 10.0 27 4.8 0.2 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 KPI38603.1 - 0.23 10.4 3.5 8.7 5.2 0.2 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 KPI38603.1 - 0.47 10.8 2.6 8.2 6.8 0.0 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF410 PF04190.13 KPI38603.1 - 0.72 9.6 3.4 12 5.5 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF410) Coatomer_E PF04733.14 KPI38603.1 - 0.75 9.1 2.7 19 4.6 0.1 2.7 2 1 1 3 3 3 0 Coatomer epsilon subunit MTBP_C PF14920.6 KPI38603.1 - 2.5 7.8 5.4 4.4 7.0 5.4 1.3 1 0 0 1 1 1 0 MDM2-binding Abhydrolase_3 PF07859.13 KPI38604.1 - 1.2e-34 120.0 0.0 1.7e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KPI38604.1 - 0.00031 20.6 0.0 0.0034 17.2 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KPI38604.1 - 0.0014 19.3 0.8 0.0023 18.6 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI38604.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KPI38604.1 - 0.0047 15.7 0.0 0.0068 15.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 KPI38604.1 - 0.014 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KPI38604.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KPI38604.1 - 0.13 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Metallothio PF00131.20 KPI38605.1 - 0.058 13.5 7.5 0.074 13.2 7.5 1.1 1 0 0 1 1 1 0 Metallothionein HR1 PF02185.16 KPI38607.1 - 3.3e-29 100.8 12.9 1.7e-15 56.9 2.6 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KPI38607.1 - 8.8e-13 47.9 15.1 4.5e-11 42.5 9.7 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KPI38607.1 - 3.4e-07 30.5 0.1 6.3e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 C2 domain Uds1 PF15456.6 KPI38607.1 - 0.54 10.4 6.5 0.63 10.2 0.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Cmc1 PF08583.10 KPI38609.1 - 1e-16 60.7 0.5 1.3e-16 60.4 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Hydrolase_4 PF12146.8 KPI38610.1 - 0.00033 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyoxalase_3 PF13468.6 KPI38611.1 - 3e-20 73.0 0.0 5.6e-20 72.2 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase-like domain Nse4_C PF08743.10 KPI38612.1 - 1.9e-25 88.9 2.8 2.4e-25 88.6 0.0 2.7 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KPI38612.1 - 2.2e-15 56.5 0.1 2.2e-15 56.5 0.1 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Methyltransf_11 PF08241.12 KPI38613.1 - 1.2e-05 25.8 0.0 3.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI38613.1 - 0.059 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cg6151-P PF10233.9 KPI38614.1 - 4.5e-43 146.1 15.1 5.3e-43 145.9 15.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2207 PF09972.9 KPI38614.1 - 0.26 10.0 11.4 0.4 9.4 11.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 KPI38614.1 - 3.4 7.8 9.3 4.8 7.3 9.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_holin_3_6 PF07332.11 KPI38614.1 - 3.8 7.6 16.5 0.09 12.8 3.3 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5592 PF17332.2 KPI38614.1 - 5.9 7.5 8.9 0.7 10.5 3.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DAD PF02109.16 KPI38615.1 - 9.7e-42 141.7 0.5 1.9e-41 140.8 0.5 1.5 1 1 0 1 1 1 1 DAD family TMCO5 PF14992.6 KPI38616.1 - 0.0045 16.6 0.4 0.0061 16.2 0.4 1.1 1 0 0 1 1 1 1 TMCO5 family HisKA_3 PF07730.13 KPI38616.1 - 0.15 12.6 4.7 0.11 13.0 1.1 2.4 1 1 1 2 2 2 0 Histidine kinase DivIVA PF05103.13 KPI38616.1 - 0.73 9.9 5.3 0.22 11.6 1.5 1.9 2 0 0 2 2 2 0 DivIVA protein TMF_TATA_bd PF12325.8 KPI38616.1 - 2.1 8.6 5.5 0.53 10.5 1.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding S-AdoMet_synt_C PF02773.16 KPI38618.1 - 5.7e-66 220.7 0.3 9.3e-66 220.0 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KPI38618.1 - 2.5e-32 111.6 2.0 3e-16 59.7 0.0 2.7 2 1 1 3 3 3 2 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KPI38618.1 - 1.5e-31 109.0 0.6 3.2e-31 107.9 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain SRP9-21 PF05486.12 KPI38619.1 - 5.1e-23 81.3 8.8 4.8e-22 78.2 8.8 2.1 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Dicty_REP PF05086.12 KPI38619.1 - 0.084 10.9 0.9 0.095 10.7 0.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Imm35 PF15567.6 KPI38619.1 - 0.096 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 35 CSG2 PF16965.5 KPI38619.1 - 0.12 11.3 0.3 0.16 10.9 0.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator AAA PF00004.29 KPI38620.1 - 1.1e-15 58.2 0.0 2.3e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KPI38620.1 - 2.6e-11 43.5 0.1 7e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KPI38620.1 - 3.5e-09 37.1 0.0 1.4e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI38620.1 - 2.3e-08 34.6 0.1 2.8e-07 31.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KPI38620.1 - 7.7e-05 22.5 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KPI38620.1 - 0.0016 18.8 0.0 0.0064 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KPI38620.1 - 0.028 14.2 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI38620.1 - 0.046 13.4 2.3 0.13 12.0 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KPI38620.1 - 0.06 13.5 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI38620.1 - 0.083 13.4 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPI38620.1 - 0.089 13.0 1.3 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KPI38620.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KPI38620.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SPT6_acidic PF14632.6 KPI38620.1 - 6.8 7.4 7.8 26 5.5 1.1 2.8 3 0 0 3 3 2 0 Acidic N-terminal SPT6 PAPS_reduct PF01507.19 KPI38621.1 - 4.7e-21 75.6 0.0 1.4e-20 74.1 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3449 PF11931.8 KPI38622.1 - 5.3e-72 241.5 0.1 1.2e-71 240.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KPI38622.1 - 3.8e-25 88.2 0.7 1e-24 86.8 0.1 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KPI38622.1 - 5.5e-11 42.2 1.3 1.1e-10 41.2 1.3 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KPI38622.1 - 1.2e-09 38.2 1.1 3e-07 30.6 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KPI38622.1 - 1.3e-07 31.7 0.1 1.3e-07 31.7 0.1 3.1 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 KPI38622.1 - 0.00014 21.9 8.5 0.15 12.1 0.7 3.4 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KPI38622.1 - 0.00069 19.9 0.3 0.047 14.0 0.0 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPI38622.1 - 0.08 13.8 0.6 12 7.0 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 KPI38622.1 - 0.14 11.9 0.1 0.44 10.4 0.1 1.8 1 0 0 1 1 1 0 U1 zinc finger SOG2 PF10428.9 KPI38623.1 - 0.016 14.4 17.7 0.021 14.0 17.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Herpes_TAF50 PF03326.13 KPI38623.1 - 0.074 11.7 17.2 0.11 11.1 17.2 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Ndc1_Nup PF09531.10 KPI38623.1 - 6.4 5.3 9.5 9.4 4.8 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KPI38623.1 - 8.3 5.1 6.7 10 4.9 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATG16 PF08614.11 KPI38624.1 - 3.1e-40 138.5 22.2 3.9e-40 138.2 22.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MSL1_dimer PF16801.5 KPI38624.1 - 0.0025 17.5 7.0 0.0025 17.5 7.0 2.4 2 0 0 2 2 2 1 Dimerisation domain of Male-specific-Lethal 1 DUF4201 PF13870.6 KPI38624.1 - 0.0041 16.9 17.2 0.0064 16.2 17.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF812 PF05667.11 KPI38624.1 - 0.033 13.1 12.3 0.035 13.0 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 KPI38624.1 - 0.035 14.2 18.8 0.56 10.3 11.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 KPI38624.1 - 0.059 12.8 15.0 0.086 12.3 15.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 KPI38624.1 - 0.071 12.0 3.6 0.08 11.8 3.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KPI38624.1 - 0.08 12.3 12.7 0.1 12.0 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KPI38624.1 - 0.13 9.8 19.2 0.16 9.5 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MutS_III PF05192.18 KPI38624.1 - 0.15 12.3 7.5 0.19 12.0 7.5 1.1 1 0 0 1 1 1 0 MutS domain III Flagellar_rod PF05149.12 KPI38624.1 - 0.19 11.1 16.3 0.26 10.7 16.3 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein Exonuc_VII_L PF02601.15 KPI38624.1 - 0.25 10.9 8.9 0.26 10.8 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BRE1 PF08647.11 KPI38624.1 - 2.5 8.3 23.3 0.25 11.4 17.6 2.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KPI38624.1 - 4.4 6.1 19.9 9.3 5.0 19.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KPI38624.1 - 9.5 6.8 25.2 12 6.4 9.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1863 PF08937.11 KPI38625.1 - 0.17 12.2 0.6 10 6.4 0.1 2.4 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) His_Phos_1 PF00300.22 KPI38626.1 - 1.3e-33 116.4 0.5 4.7e-16 59.1 0.2 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) G-alpha PF00503.20 KPI38627.1 - 3.7e-107 358.6 0.5 4.3e-107 358.3 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KPI38627.1 - 2.9e-14 52.9 0.3 4.8e-09 35.9 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPI38627.1 - 0.0015 18.0 3.0 0.14 11.5 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KPI38627.1 - 0.0026 18.0 0.3 0.66 10.2 0.0 3.1 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KPI38627.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KPI38627.1 - 0.068 12.7 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPI38627.1 - 0.094 12.8 0.0 23 5.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase MFS_1 PF07690.16 KPI38628.1 - 1.4e-33 116.3 40.6 4.7e-33 114.6 19.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38628.1 - 1.4e-10 40.7 5.5 1.4e-10 40.7 5.5 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI38628.1 - 0.0083 14.6 4.6 0.015 13.8 4.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 KPI38628.1 - 0.88 9.4 5.6 3.9 7.4 0.1 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Vut_1 PF02592.15 KPI38628.1 - 2.4 8.5 20.3 0.16 12.3 1.8 3.9 3 1 1 4 4 4 0 Putative vitamin uptake transporter Fungal_trans PF04082.18 KPI38629.1 - 8.5e-12 44.7 0.2 1.6e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KPI38629.1 - 0.013 15.9 3.1 0.013 15.9 3.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KPI38629.1 - 0.062 13.8 1.9 0.22 12.1 1.9 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI38629.1 - 3.5 8.7 7.1 0.3 12.0 1.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Laminin_II PF06009.12 KPI38630.1 - 0.12 12.3 0.5 0.36 10.8 0.2 1.9 2 0 0 2 2 2 0 Laminin Domain II GTP_EFTU PF00009.27 KPI38631.1 - 1.4e-57 194.4 0.2 3.4e-57 193.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KPI38631.1 - 2.5e-14 53.0 0.0 6.9e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KPI38631.1 - 1.4e-07 31.5 0.0 2.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KPI38631.1 - 2.1e-06 28.0 0.0 5.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KPI38631.1 - 0.034 13.9 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KPI38631.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase EamA PF00892.20 KPI38632.1 - 6.8e-11 42.5 35.7 1e-07 32.2 4.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KPI38632.1 - 4.5e-07 29.6 1.2 4.5e-07 29.6 1.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 KPI38632.1 - 0.00095 18.8 4.4 0.011 15.2 0.3 3.0 2 1 1 3 3 3 1 Solute carrier family 35 UAA PF08449.11 KPI38632.1 - 0.15 11.2 9.4 0.0088 15.3 3.8 1.7 2 1 0 2 2 2 0 UAA transporter family PUNUT PF16913.5 KPI38632.1 - 3.6 6.7 9.7 0.19 10.9 0.3 2.6 3 0 0 3 3 3 0 Purine nucleobase transmembrane transport HypA PF01155.19 KPI38634.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RasGEF PF00617.19 KPI38635.1 - 1.8e-59 200.9 0.1 5.1e-59 199.4 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KPI38635.1 - 6.8e-29 100.2 0.1 1.4e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KPI38635.1 - 6.1e-15 54.6 0.2 1.3e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI38635.1 - 5.5e-13 48.6 0.2 1.3e-12 47.4 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI38635.1 - 3e-10 39.6 0.5 6.3e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 KPI38635.1 - 0.00021 21.3 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 WW domain Ras PF00071.22 KPI38636.1 - 5.8e-57 191.8 0.1 6.8e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI38636.1 - 1.1e-32 112.8 0.0 1.7e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI38636.1 - 2.2e-13 50.0 0.0 2.5e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPI38636.1 - 1.5e-08 34.7 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPI38636.1 - 1.7e-07 30.9 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KPI38636.1 - 2.1e-05 24.5 0.1 0.0025 17.7 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KPI38636.1 - 2.1e-05 24.1 0.1 0.00067 19.2 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KPI38636.1 - 0.002 17.7 0.0 0.0072 15.9 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KPI38636.1 - 0.0021 17.5 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KPI38636.1 - 0.0032 17.3 0.3 0.1 12.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KPI38636.1 - 0.0097 16.3 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPI38636.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KPI38636.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KPI38636.1 - 0.02 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KPI38636.1 - 0.02 14.6 0.1 0.099 12.4 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KPI38636.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KPI38636.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KPI38636.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KPI38636.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KPI38636.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KPI38636.1 - 0.14 11.3 0.2 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 KPI38636.1 - 0.22 12.0 0.2 0.28 11.7 0.2 1.7 1 1 0 1 1 1 0 ABC transporter PNP_phzG_C PF10590.9 KPI38638.1 - 3.6e-22 78.1 2.2 9.9e-22 76.8 1.6 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KPI38638.1 - 9.8e-19 67.3 0.0 1.5e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KPI38638.1 - 0.0068 17.0 0.1 0.011 16.3 0.1 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DHR-2 PF06920.13 KPI38639.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Dock homology region 2 RPOL_N PF14700.6 KPI38640.1 - 6.8e-85 285.4 3.6 9.3e-85 285.0 3.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal EnY2 PF10163.9 KPI38640.1 - 1.8 9.0 6.2 2.2 8.7 0.0 3.3 3 0 0 3 3 3 0 Transcription factor e(y)2 VPS11_C PF12451.8 KPI38641.1 - 2.9e-19 69.0 0.3 7.2e-19 67.7 0.3 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 KPI38641.1 - 4.1e-18 65.6 3.7 5.7e-18 65.2 0.7 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KPI38641.1 - 1.7e-05 24.5 6.3 3.6e-05 23.5 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI38641.1 - 2.8e-05 24.4 5.6 5.6e-05 23.4 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPI38641.1 - 0.00013 21.9 6.0 0.00025 20.9 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 KPI38641.1 - 0.00056 19.9 7.2 0.0023 17.9 7.2 2.0 1 1 0 1 1 1 1 Zinc-finger TPR_11 PF13414.6 KPI38641.1 - 0.00083 19.0 0.1 0.0022 17.6 0.1 1.7 1 0 0 1 1 1 1 TPR repeat zf-RING_UBOX PF13445.6 KPI38641.1 - 0.00085 19.3 3.2 0.0017 18.3 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KPI38641.1 - 0.0016 18.7 4.5 0.0032 17.7 4.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_14 PF13428.6 KPI38641.1 - 0.0042 17.8 1.3 0.28 12.1 0.0 3.9 5 0 0 5 5 2 1 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KPI38641.1 - 0.0058 16.5 6.4 0.011 15.6 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Mcl1_mid PF12341.8 KPI38641.1 - 0.0072 15.7 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region zf-ANAPC11 PF12861.7 KPI38641.1 - 0.013 15.5 0.8 0.029 14.4 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 KPI38641.1 - 0.059 13.6 1.6 0.12 12.6 1.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4810 PF16068.5 KPI38641.1 - 0.081 13.5 0.2 23 5.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) eIF3_N PF09440.10 KPI38641.1 - 0.091 13.2 0.8 0.29 11.6 0.8 1.9 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain TPR_2 PF07719.17 KPI38641.1 - 0.094 12.9 1.1 0.61 10.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40_like PF17005.5 KPI38641.1 - 0.14 11.5 0.1 2.9 7.1 0.0 2.2 2 1 0 2 2 2 0 WD40-like domain zf-C3HC4_4 PF15227.6 KPI38641.1 - 0.55 10.4 4.5 1.1 9.4 4.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_8 PF13181.6 KPI38641.1 - 2.2 8.7 6.6 1.2 9.5 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI38641.1 - 2.9 7.9 4.6 3.2 7.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KPI38641.1 - 3.3 7.6 5.0 6.5 6.7 5.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KPI38641.1 - 3.4 7.6 6.6 4.7 7.2 5.0 2.1 2 0 0 2 2 2 0 PHD-finger WD40 PF00400.32 KPI38642.1 - 1e-15 57.8 1.2 0.0042 17.9 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38642.1 - 5.9e-07 29.7 0.0 0.0038 17.5 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI38642.1 - 5.6e-06 25.3 2.7 0.0001 21.1 0.2 3.0 2 2 0 3 3 3 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 KPI38642.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.6 KPI38642.1 - 0.13 12.8 0.9 2.1 8.9 0.0 3.4 3 1 0 3 3 3 0 PQQ-like domain Arrestin_C PF02752.22 KPI38643.1 - 9.5e-21 74.6 0.0 2.4e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KPI38643.1 - 1.3e-07 31.8 0.0 0.00012 22.1 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain FMN_dh PF01070.18 KPI38645.1 - 1.5e-107 359.7 0.1 2.4e-106 355.7 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KPI38645.1 - 2.8e-09 36.5 0.3 6.1e-09 35.3 0.2 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPI38645.1 - 8.5e-07 28.7 0.9 1.3e-06 28.0 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KPI38645.1 - 1.1e-06 28.0 0.1 1.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KPI38645.1 - 3.6e-05 23.3 0.1 0.00028 20.4 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KPI38645.1 - 0.0026 17.1 0.9 0.057 12.7 0.1 2.2 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KPI38645.1 - 0.042 13.1 0.0 0.11 11.6 0.0 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Transketolase_N PF00456.21 KPI38646.1 - 2.7e-150 500.0 0.4 3.5e-150 499.6 0.4 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KPI38646.1 - 1.3e-44 152.0 0.0 2.3e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPI38646.1 - 1e-13 51.2 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KPI38646.1 - 0.00027 20.2 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KPI38646.1 - 0.00097 18.2 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component GtrA PF04138.14 KPI38646.1 - 0.041 14.1 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein Beta_elim_lyase PF01212.21 KPI38646.1 - 0.055 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PRMT5 PF05185.16 KPI38647.1 - 2.9e-66 222.6 0.0 6.6e-66 221.4 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KPI38647.1 - 9.1e-65 218.4 0.0 1.3e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KPI38647.1 - 5.1e-52 176.3 0.1 7.4e-51 172.5 0.1 2.4 1 1 0 1 1 1 1 PRMT5 oligomerisation domain HEAT_EZ PF13513.6 KPI38648.1 - 7.5e-26 90.2 6.2 4.2e-16 59.1 0.1 9.0 7 3 3 10 10 10 2 HEAT-like repeat HEAT PF02985.22 KPI38648.1 - 1.2e-24 84.2 5.7 6.6e-06 25.9 0.0 9.2 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.6 KPI38648.1 - 2.4e-14 53.5 0.2 0.00044 20.6 0.0 6.7 5 1 2 7 7 7 3 HEAT repeats IBN_N PF03810.19 KPI38648.1 - 1.6e-10 40.7 1.7 5.1e-07 29.5 0.1 5.1 3 1 2 5 5 5 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KPI38648.1 - 2.4e-10 40.7 0.3 0.0012 18.9 0.0 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPI38648.1 - 2.3e-09 37.7 0.0 0.0023 18.5 0.0 5.6 3 3 4 7 7 7 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KPI38648.1 - 0.00029 20.1 3.2 0.027 13.6 0.0 4.0 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KPI38648.1 - 0.0003 20.4 0.2 4.1 6.9 0.0 4.5 4 0 0 4 4 4 1 CLASP N terminal DUF3437 PF11919.8 KPI38648.1 - 0.00086 19.2 0.1 0.09 12.7 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 KPI38648.1 - 0.002 18.6 2.9 1.5 9.7 0.0 5.3 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KPI38648.1 - 0.017 15.3 0.8 6.8 6.9 0.0 4.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KPI38648.1 - 0.037 13.7 2.6 8.2 6.1 0.1 4.6 5 2 0 6 6 6 0 rRNA processing/ribosome biogenesis TIP120 PF08623.10 KPI38648.1 - 0.079 12.7 0.2 2.9 7.6 0.0 3.3 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Git3 PF11710.8 KPI38649.1 - 2.2e-20 73.3 16.9 5e-20 72.1 16.9 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KPI38649.1 - 1e-06 28.7 0.9 1e-06 28.7 0.9 2.3 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KPI38649.1 - 0.012 14.7 14.7 0.018 14.2 14.7 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Phage_holin_2_4 PF16082.5 KPI38649.1 - 0.15 11.8 1.9 5.4 6.8 0.3 2.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Striatin PF08232.12 KPI38650.1 - 0.16 12.6 0.1 0.28 11.8 0.1 1.7 1 1 0 1 1 1 0 Striatin family Usp PF00582.26 KPI38651.1 - 1.6e-17 64.4 1.7 3.5e-16 60.0 0.1 2.8 2 1 0 2 2 2 1 Universal stress protein family DEAD PF00270.29 KPI38652.1 - 3.3e-43 147.5 0.1 5.3e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI38652.1 - 6.7e-29 100.5 0.0 5e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KPI38652.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KPI38652.1 - 0.00018 21.6 0.0 0.00033 20.7 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KPI38652.1 - 0.0019 18.6 0.1 0.0031 17.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KPI38652.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KPI38652.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 KPI38652.1 - 0.057 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KPI38652.1 - 0.12 12.7 0.7 0.49 10.7 0.7 1.9 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KPI38653.1 - 5.1e-44 150.6 42.4 7.6e-44 150.1 42.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38653.1 - 4.8e-17 62.0 11.4 4.8e-17 62.0 11.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KPI38653.1 - 4.5e-08 32.0 23.3 6.1e-08 31.5 23.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3425 PF11905.8 KPI38654.1 - 3.4e-11 43.2 0.0 8.9e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_3 PF01494.19 KPI38655.1 - 4.9e-65 220.1 0.0 2.2e-50 171.9 0.0 2.5 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 KPI38655.1 - 4.2e-57 192.8 0.0 7e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KPI38655.1 - 0.00058 19.2 0.1 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI38655.1 - 0.0013 17.5 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KPI38655.1 - 0.0028 16.8 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPI38655.1 - 0.0098 16.1 0.0 0.056 13.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI38655.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI38655.1 - 0.017 14.3 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KPI38655.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KPI38655.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DcpS_C PF11969.8 KPI38656.1 - 2.8e-15 56.8 5.1 2.7e-14 53.6 5.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 KPI38656.1 - 4.5e-13 49.4 1.2 1.7e-12 47.6 0.1 2.3 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KPI38656.1 - 5e-12 46.4 0.1 1.2e-11 45.1 0.1 1.7 1 1 0 1 1 1 1 HIT domain Rho_GDI PF02115.17 KPI38657.1 - 7e-63 211.9 0.0 8.2e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor NMO PF03060.15 KPI38658.1 - 8.9e-50 169.9 3.2 1.3e-49 169.4 3.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI38658.1 - 2.9e-08 33.1 4.8 7.2e-08 31.8 4.8 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KPI38658.1 - 2.2e-06 27.0 3.4 5e-06 25.8 3.4 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KPI38658.1 - 0.0028 16.9 0.7 0.0054 15.9 0.7 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KPI38658.1 - 0.069 12.4 0.6 0.16 11.1 0.6 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SCP2_2 PF13530.6 KPI38658.1 - 0.098 13.1 0.1 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 Sterol carrier protein domain DUF5446 PF17522.2 KPI38658.1 - 0.1 12.8 0.3 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5446) RHH_1 PF01402.21 KPI38658.1 - 0.11 12.5 0.5 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PTPLA PF04387.14 KPI38659.1 - 4.1e-57 192.5 4.8 6.2e-57 191.9 4.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Fungal_trans PF04082.18 KPI38660.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain TruB_N PF01509.18 KPI38662.1 - 2.7e-41 141.4 0.0 2.1e-40 138.5 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KPI38662.1 - 0.0087 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF775 PF05603.12 KPI38663.1 - 1.2e-60 204.4 0.0 1.6e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Asp PF00026.23 KPI38664.1 - 2e-15 57.0 0.0 4e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KPI38664.1 - 0.021 14.2 1.0 0.039 13.4 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KPI38664.1 - 0.077 11.8 0.5 0.15 10.9 0.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein TAXi_N PF14543.6 KPI38664.1 - 0.084 13.1 0.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal PRP38 PF03371.15 KPI38665.1 - 1.9e-59 200.4 0.0 2.2e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family F-box PF00646.33 KPI38666.1 - 0.012 15.5 0.2 0.062 13.2 0.1 2.4 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KPI38666.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like Asp_Glu_race PF01177.22 KPI38667.1 - 1.4e-40 139.5 0.0 1.6e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PA PF02225.22 KPI38667.1 - 0.056 13.5 0.1 4 7.5 0.0 2.3 2 0 0 2 2 2 0 PA domain UPF0086 PF01868.16 KPI38668.1 - 1.9e-25 88.6 1.0 2.9e-25 88.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Lactonase PF10282.9 KPI38668.1 - 0.032 13.5 0.5 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller HLH PF00010.26 KPI38669.1 - 1.2e-07 31.5 2.5 2.5e-07 30.5 2.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1664 PF07889.12 KPI38669.1 - 0.042 13.9 1.5 0.07 13.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 KPI38669.1 - 0.28 11.0 2.7 0.31 10.8 0.5 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain RNA_pol_Rpb8 PF03870.15 KPI38670.1 - 6.2e-41 139.9 0.0 7.2e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KPI38670.1 - 3.7e-05 23.8 0.1 0.0031 17.6 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Phosducin PF02114.16 KPI38672.1 - 5.7e-06 25.5 0.0 0.0053 15.7 0.0 2.3 2 0 0 2 2 2 2 Phosducin WD40 PF00400.32 KPI38673.1 - 5.2e-46 153.7 17.8 4.1e-09 36.9 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38673.1 - 2.2e-07 31.1 1.1 0.82 10.0 0.0 5.4 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPI38673.1 - 0.0017 17.7 0.0 0.0083 15.5 0.0 2.0 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KPI38673.1 - 0.064 11.9 4.6 11 4.5 0.0 4.1 2 1 3 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPI38673.1 - 0.12 11.1 0.0 8.2 5.0 0.0 3.6 2 1 0 2 2 2 0 Nup133 N terminal like RRN3 PF05327.11 KPI38674.1 - 8.4e-139 463.7 1.1 9.9e-139 463.4 1.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 KPI38674.1 - 0.00022 20.4 3.6 0.00045 19.4 3.6 1.5 1 0 0 1 1 1 1 Pes-10 Allexi_40kDa PF05549.11 KPI38674.1 - 0.097 12.2 1.0 0.18 11.3 1.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein EXOSC1 PF10447.9 KPI38675.1 - 9.4e-15 55.2 4.3 5.5e-12 46.3 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KPI38675.1 - 1e-08 34.8 0.6 2.2e-08 33.8 0.6 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Glyco_transf_15 PF01793.16 KPI38676.1 - 6.5e-23 81.5 0.0 7.7e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Fungal_trans_2 PF11951.8 KPI38677.1 - 2.6e-07 29.8 1.3 1.1e-06 27.8 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain GSHPx PF00255.19 KPI38678.1 - 6.3e-38 128.7 0.1 8.2e-38 128.3 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KPI38678.1 - 0.011 15.6 0.3 0.077 12.9 0.3 2.3 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KPI38678.1 - 0.13 12.0 0.7 1.3 8.7 0.7 2.3 1 1 0 1 1 1 0 Redoxin ArfGap PF01412.18 KPI38679.1 - 8e-34 116.2 0.2 1.4e-33 115.5 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Syja_N PF02383.18 KPI38680.1 - 8e-89 298.1 0.0 1.3e-88 297.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KPI38680.1 - 9.3e-37 125.3 0.0 2.3e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase TAP_C PF03943.13 KPI38680.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 TAP C-terminal domain Scm3 PF10384.9 KPI38680.1 - 0.11 12.3 0.0 0.91 9.3 0.0 2.4 2 0 0 2 2 2 0 Centromere protein Scm3 tRNA_SAD PF07973.14 KPI38681.1 - 7.5e-05 22.7 0.4 0.00021 21.3 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KPI38681.1 - 0.00014 20.6 0.0 0.00018 20.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) TcpQ PF10671.9 KPI38681.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q DHHC PF01529.20 KPI38682.1 - 1.4e-34 119.0 12.3 1.4e-34 119.0 12.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Acetyltransf_10 PF13673.7 KPI38682.1 - 5.9e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI38682.1 - 9.1e-06 25.9 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI38682.1 - 1.2e-05 25.6 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI38682.1 - 0.00022 21.3 0.1 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KPI38682.1 - 0.0027 17.3 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 KPI38682.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4336 PF14234.6 KPI38683.1 - 2e-19 70.0 0.1 1.6e-13 50.5 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) An_peroxidase PF03098.15 KPI38684.1 - 1.8e-96 323.9 0.0 7.6e-76 255.8 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase MKT1_C PF12246.8 KPI38685.1 - 4.6e-50 170.1 0.0 8.9e-50 169.2 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KPI38685.1 - 9.3e-23 80.4 0.2 4.4e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication DIOX_N PF14226.6 KPI38685.1 - 2.9e-16 60.3 0.0 1.4e-15 58.1 0.0 2.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI38685.1 - 7.3e-16 58.5 0.0 2.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RCC1_2 PF13540.6 KPI38685.1 - 3.3e-09 36.3 17.4 0.00035 20.3 0.0 4.6 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat XPG_I PF00867.18 KPI38685.1 - 0.0034 17.7 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region zf-C3HC4_2 PF13923.6 KPI38686.1 - 2.9e-11 43.0 9.9 2.9e-11 43.0 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI38686.1 - 1.9e-09 37.4 8.3 5.4e-09 35.9 8.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI38686.1 - 7.3e-09 35.4 10.8 7.3e-09 35.4 10.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI38686.1 - 8.9e-08 31.9 8.1 8.9e-08 31.9 8.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI38686.1 - 7.9e-07 28.9 10.5 7.9e-07 28.9 10.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KPI38686.1 - 4.9e-06 26.3 2.3 4.9e-06 26.3 2.3 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KPI38686.1 - 8.8e-06 26.0 10.2 8.8e-06 26.0 10.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KPI38686.1 - 9.6e-05 22.6 6.2 9.6e-05 22.6 6.2 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KPI38686.1 - 0.00011 22.0 11.1 0.00058 19.7 8.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KPI38686.1 - 0.00031 20.9 0.5 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-C3HC4_4 PF15227.6 KPI38686.1 - 0.00031 20.8 12.9 0.00039 20.5 10.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KPI38686.1 - 0.00053 20.1 4.8 0.0011 19.0 4.8 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 SAP PF02037.27 KPI38686.1 - 0.00094 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain Mob_synth_C PF06463.13 KPI38686.1 - 0.0029 17.5 2.2 0.0071 16.3 2.2 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.6 KPI38686.1 - 0.0034 17.1 2.9 0.0034 17.1 2.9 2.6 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Sgf11 PF08209.11 KPI38686.1 - 0.0053 16.3 2.0 0.007 15.9 0.1 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-ANAPC11 PF12861.7 KPI38686.1 - 0.031 14.3 2.3 0.081 13.0 2.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KPI38686.1 - 0.094 12.5 6.0 0.22 11.4 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TRAF6_Z2 PF18048.1 KPI38686.1 - 0.15 12.2 0.9 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zinc-ribbons_6 PF07191.12 KPI38686.1 - 0.26 11.3 9.7 1.7 8.6 6.5 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-WRNIP1_ubi PF18279.1 KPI38686.1 - 0.7 10.7 0.0 0.7 10.7 0.0 3.1 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF1272 PF06906.11 KPI38686.1 - 3.4 7.8 11.2 0.96 9.6 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-P11 PF03854.14 KPI38686.1 - 5 6.9 8.5 28 4.5 7.7 2.3 1 1 1 2 2 2 0 P-11 zinc finger Metallophos PF00149.28 KPI38687.1 - 5.7e-37 128.2 0.4 6.5e-37 128.0 0.4 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI38687.1 - 0.086 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 KPI38688.1 - 6.1e-61 206.1 0.0 1.3e-60 205.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI38688.1 - 2.1e-26 92.8 0.0 4.4e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KPI38688.1 - 0.00073 18.9 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KPI38688.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPI38688.1 - 0.031 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_14 PF13428.6 KPI38689.1 - 0.26 12.2 1.8 6.4 7.9 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Mob1_phocein PF03637.17 KPI38690.1 - 1.5e-35 122.7 1.3 8.6e-34 117.0 1.3 2.4 1 1 0 1 1 1 1 Mob1/phocein family HABP4_PAI-RBP1 PF04774.15 KPI38691.1 - 0.13 13.2 2.3 0.24 12.2 2.3 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family GST_N_3 PF13417.6 KPI38693.1 - 1.3e-10 41.5 0.2 4.2e-10 39.9 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI38693.1 - 1e-08 35.4 0.1 1.8e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI38693.1 - 0.059 13.4 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UvsW PF11637.8 KPI38693.1 - 0.11 12.7 1.0 0.2 11.7 0.6 1.7 1 1 0 1 1 1 0 ATP-dependant DNA helicase UvsW RSN1_TM PF13967.6 KPI38695.1 - 7.4e-42 142.8 0.5 1.3e-41 141.9 0.5 1.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPI38695.1 - 3.7e-19 69.6 0.1 4.3e-09 36.8 0.1 2.6 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Atrophin-1 PF03154.15 KPI38696.1 - 1.1 7.4 10.7 1.5 7.0 10.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.11 KPI38696.1 - 4.6 7.2 8.5 0.3 11.1 3.2 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RNA_pol_Rpc34 PF05158.12 KPI38697.1 - 1.3e-60 205.5 0.0 2.3e-60 204.7 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit FMN_red PF03358.15 KPI38698.1 - 5.9e-10 39.1 0.0 9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 KPI38698.1 - 0.00016 21.9 0.6 0.0045 17.2 0.3 2.5 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 KPI38698.1 - 0.032 14.5 0.0 1.4 9.1 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_2 PF02525.17 KPI38698.1 - 0.042 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Nucleotid_trans PF03407.16 KPI38699.1 - 2.2e-15 57.2 0.3 3.9e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pmp3 PF01679.17 KPI38699.1 - 7.2e-14 51.7 2.0 1.6e-13 50.7 0.6 2.1 2 0 0 2 2 2 1 Proteolipid membrane potential modulator PTP_N PF12453.8 KPI38699.1 - 0.24 11.1 2.2 0.58 9.9 1.7 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal bZIP_1 PF00170.21 KPI38700.1 - 0.00014 21.8 5.5 0.00025 21.1 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI38700.1 - 0.0048 16.9 7.0 0.0078 16.3 7.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPI38700.1 - 0.0073 16.8 4.1 0.013 16.0 4.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor LTXXQ PF07813.12 KPI38700.1 - 0.78 10.5 4.5 12 6.7 2.1 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein Aim19 PF10315.9 KPI38702.1 - 0.028 14.7 0.4 0.041 14.2 0.4 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 NdhL PF10716.9 KPI38702.1 - 0.44 10.5 4.2 0.61 10.1 1.3 2.3 2 1 1 3 3 3 0 NADH dehydrogenase transmembrane subunit Gram_pos_anchor PF00746.21 KPI38702.1 - 0.95 9.5 4.7 18 5.4 0.8 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Atg8 PF02991.16 KPI38703.1 - 2.8e-51 172.0 0.2 3.3e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KPI38703.1 - 3.1e-06 27.5 0.0 3.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RTA1 PF04479.13 KPI38704.1 - 2.9e-52 177.3 4.1 4.3e-52 176.7 4.1 1.2 1 0 0 1 1 1 1 RTA1 like protein FAD-oxidase_C PF02913.19 KPI38705.1 - 1e-60 205.5 0.2 1.5e-60 204.9 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KPI38705.1 - 1.7e-36 125.0 0.0 2.9e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AAA_23 PF13476.6 KPI38706.1 - 3.4e-27 96.2 4.9 3.4e-27 96.2 4.9 7.9 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.6 KPI38706.1 - 6.2e-16 59.1 5.2 4.6e-10 39.7 0.0 4.4 1 1 2 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.6 KPI38706.1 - 4.8e-06 26.7 0.0 2.3e-05 24.5 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KPI38706.1 - 1.2e-05 25.3 17.6 0.0013 18.7 0.1 4.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI38706.1 - 0.0011 18.4 49.5 0.019 14.4 49.5 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI38706.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KPI38706.1 - 0.12 12.7 0.0 0.12 12.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 KPI38706.1 - 0.17 12.3 0.0 0.17 12.3 0.0 5.5 6 1 0 6 6 6 0 AAA ATPase domain DUF4162 PF13732.6 KPI38706.1 - 2.1 9.1 0.0 2.1 9.1 0.0 6.1 6 2 1 7 7 7 0 Domain of unknown function (DUF4162) Dynactin_p62 PF05502.13 KPI38707.1 - 2.7e-139 465.0 1.6 1.1e-135 453.1 0.3 2.1 1 1 1 2 2 2 2 Dynactin p62 family Mu-like_Com PF10122.9 KPI38707.1 - 0.44 10.0 3.5 2.8 7.5 0.5 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com DEAD PF00270.29 KPI38709.1 - 1.3e-19 70.7 0.9 6.7e-18 65.1 0.1 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI38709.1 - 3.2e-07 30.5 0.0 5.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI38709.1 - 6.6e-07 29.7 0.0 2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4332 PF14229.6 KPI38709.1 - 0.0037 17.5 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) HTH_38 PF13936.6 KPI38709.1 - 0.018 14.8 0.4 3.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_22 PF13401.6 KPI38709.1 - 0.025 14.8 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain HHH_5 PF14520.6 KPI38709.1 - 0.09 13.4 0.0 0.49 11.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain FAD_binding_4 PF01565.23 KPI38712.1 - 1.6e-16 60.3 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Imm41 PF15592.6 KPI38712.1 - 0.1 12.9 0.6 0.22 11.9 0.6 1.4 1 0 0 1 1 1 0 Immunity protein 41 Fungal_trans PF04082.18 KPI38713.1 - 3.9e-20 72.0 1.7 5.2e-20 71.6 1.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI38713.1 - 0.00029 20.9 11.6 0.00066 19.7 11.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NT-C2 PF10358.9 KPI38716.1 - 1.4e-31 109.2 0.0 2.5e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SR-25 PF10500.9 KPI38716.1 - 0.68 9.5 13.7 1.4 8.5 13.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM76 PF16046.5 KPI38716.1 - 3.3 7.0 5.8 5.9 6.1 5.8 1.3 1 0 0 1 1 1 0 FAM76 protein Macoilin PF09726.9 KPI38716.1 - 6 5.3 8.4 8.1 4.9 8.4 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_L37e PF01907.19 KPI38717.1 - 4.2e-28 97.3 12.6 6e-28 96.8 12.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KPI38717.1 - 0.0057 16.7 1.1 0.0083 16.1 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_10 PF16685.5 KPI38717.1 - 0.086 13.0 2.3 0.11 12.7 2.3 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 HypA PF01155.19 KPI38717.1 - 0.087 12.8 0.7 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 KPI38717.1 - 0.096 12.6 3.5 0.18 11.7 3.5 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C3HC4_2 PF13923.6 KPI38717.1 - 0.2 11.5 2.3 0.33 10.8 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KPI38717.1 - 0.3 10.9 3.7 7.2 6.5 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 KPI38717.1 - 0.43 10.5 4.4 0.67 9.9 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 KPI38717.1 - 1.2 8.6 4.7 8.1 6.0 4.5 2.0 1 1 1 2 2 2 0 zinc-ribbon domain CG-1 PF03859.16 KPI38721.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 CG-1 domain GPI2 PF06432.11 KPI38722.1 - 8.7e-120 399.4 1.5 1e-119 399.1 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase ApbE PF02424.15 KPI38723.1 - 0.072 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 ApbE family DUF4452 PF14618.6 KPI38723.1 - 0.18 11.7 5.1 0.41 10.5 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RSN1_7TM PF02714.15 KPI38724.1 - 1.4e-81 273.8 33.5 2e-81 273.4 33.5 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KPI38724.1 - 8.1e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Thiolase_N PF00108.23 KPI38726.1 - 1.1e-17 64.3 0.4 1.6e-15 57.2 0.3 2.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI38726.1 - 1.1e-12 47.6 0.1 2.5e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KPI38726.1 - 6e-07 29.2 0.1 6.3e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KPI38726.1 - 2.6e-05 23.9 0.0 0.00018 21.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPI38726.1 - 0.013 15.5 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.28 KPI38727.1 - 1.8e-71 241.0 0.0 2.2e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI38727.1 - 1.3e-18 67.7 0.0 3.4e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GATA PF00320.27 KPI38728.1 - 1.9e-16 59.3 5.5 3.5e-16 58.5 5.5 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KPI38728.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KPI38728.1 - 6.7e-09 35.7 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KPI38728.1 - 6.7e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KPI38728.1 - 1.8e-06 28.1 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 KPI38728.1 - 5.7e-05 23.2 0.0 9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 KPI38728.1 - 0.013 15.6 0.2 0.032 14.4 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KPI38728.1 - 0.17 11.4 0.3 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 KPI38728.1 - 3.1 7.8 5.3 0.54 10.2 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) 2-Hacid_dh_C PF02826.19 KPI38729.1 - 2.5e-55 186.6 0.0 3.2e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI38729.1 - 7.6e-17 61.2 0.0 1.3e-16 60.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI38729.1 - 0.00071 19.8 0.1 0.0014 18.8 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KPI38729.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CHASE2 PF05226.11 KPI38729.1 - 0.038 13.7 0.0 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 CHASE2 domain F420_oxidored PF03807.17 KPI38729.1 - 0.091 13.4 0.3 0.19 12.3 0.3 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KPI38729.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Abhydrolase_3 PF07859.13 KPI38730.1 - 3.1e-32 112.2 0.0 4.3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI38730.1 - 0.00012 21.1 0.1 0.00028 19.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Amidase PF01425.21 KPI38731.1 - 1.8e-96 323.8 0.0 1.8e-95 320.5 0.0 2.3 2 1 0 2 2 2 1 Amidase TPR_1 PF00515.28 KPI38732.1 - 1.4e-45 151.3 21.8 1.7e-05 24.4 0.1 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KPI38732.1 - 1.1e-38 128.2 19.4 9.2e-06 25.4 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KPI38732.1 - 2.5e-35 120.2 8.5 1.6e-18 66.3 0.6 3.0 3 0 0 3 3 3 2 STI1 domain TPR_8 PF13181.6 KPI38732.1 - 7.7e-20 69.4 27.5 0.00025 21.0 0.1 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI38732.1 - 1.8e-17 62.7 13.0 0.00021 20.9 0.1 7.9 6 2 2 8 8 8 4 TPR repeat TPR_12 PF13424.6 KPI38732.1 - 3.7e-17 62.4 14.4 4.6e-09 36.4 0.1 5.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPI38732.1 - 1.2e-15 57.9 7.9 0.00068 20.2 0.0 6.5 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KPI38732.1 - 4.6e-15 55.9 12.3 0.043 14.3 0.2 7.0 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPI38732.1 - 1.3e-14 53.6 11.3 0.36 11.8 0.0 8.9 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPI38732.1 - 1e-10 41.1 4.1 0.66 9.9 0.0 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KPI38732.1 - 1.8e-10 40.8 0.4 0.0083 16.3 0.0 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI38732.1 - 1.3e-09 37.3 8.7 0.0011 18.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI38732.1 - 1.3e-08 34.7 8.6 0.024 15.0 0.1 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPI38732.1 - 2.6e-06 27.7 16.0 0.22 12.2 0.1 8.4 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPI38732.1 - 4.7e-05 23.4 8.4 0.32 11.1 0.0 6.0 7 1 1 8 8 7 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KPI38732.1 - 0.00052 20.2 14.4 0.074 13.3 1.3 3.9 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KPI38732.1 - 0.039 14.3 11.6 0.69 10.3 0.0 4.9 4 1 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KPI38732.1 - 0.7 9.6 0.0 0.7 9.6 0.0 4.4 5 1 1 6 6 6 0 26S proteasome subunit RPN7 NSF PF02071.20 KPI38732.1 - 1.2 10.2 3.8 37 5.7 0.1 4.3 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Alkyl_sulf_dimr PF14863.6 KPI38732.1 - 6.7 7.2 10.6 9.9 6.6 0.0 4.0 4 1 0 4 4 4 0 Alkyl sulfatase dimerisation Chromate_transp PF02417.15 KPI38733.1 - 2.2e-57 193.6 37.9 6.7e-35 120.6 12.8 2.6 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.14 KPI38733.1 - 0.2 11.0 5.4 0.72 9.1 0.2 3.3 3 0 0 3 3 3 0 Cytochrome C biogenesis protein PTPS_related PF10131.9 KPI38733.1 - 0.21 9.9 6.1 1.2 7.4 1.5 2.2 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein HemY_N PF07219.13 KPI38733.1 - 1.1 9.5 5.9 0.53 10.5 0.3 3.1 3 0 0 3 3 3 0 HemY protein N-terminus Clr5 PF14420.6 KPI38734.1 - 4.2e-19 68.5 0.1 1.9e-18 66.4 0.1 2.3 1 0 0 1 1 1 1 Clr5 domain WHAMM-JMY_N PF15920.5 KPI38734.1 - 0.11 12.4 0.3 0.27 11.1 0.3 1.6 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated LRIF1 PF15741.5 KPI38734.1 - 1.5 7.3 10.1 0.13 10.8 3.7 2.0 1 1 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 Ufd2P_core PF10408.9 KPI38735.1 - 4.8e-211 702.7 9.1 7.1e-211 702.1 9.1 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KPI38735.1 - 1.4e-25 89.2 1.6 1.4e-25 89.2 1.6 2.1 2 0 0 2 2 2 1 U-box domain OGFr_N PF04664.13 KPI38735.1 - 0.03 13.8 0.0 0.083 12.4 0.0 1.7 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region CDT1_C PF16679.5 KPI38735.1 - 0.27 11.7 4.3 3.5 8.1 0.1 3.6 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain STAT_alpha PF01017.20 KPI38735.1 - 0.59 10.0 3.4 0.65 9.9 1.3 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain DS PF01916.17 KPI38736.1 - 3.8e-131 436.6 0.0 4.4e-131 436.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Hamartin PF04388.12 KPI38737.1 - 2.5 6.7 13.2 2.7 6.6 13.2 1.1 1 0 0 1 1 1 0 Hamartin protein Het-C PF07217.11 KPI38738.1 - 1.5e-238 793.0 0.2 1.2e-237 789.9 0.2 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Abhydrolase_1 PF00561.20 KPI38739.1 - 1.5e-05 24.8 0.1 5.1e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KPI38739.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 KPI38739.1 - 0.073 13.7 0.0 0.26 11.8 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Macro PF01661.21 KPI38740.1 - 1.2e-15 57.6 0.1 4.6e-15 55.7 0.1 1.8 1 1 0 1 1 1 1 Macro domain DUF2970 PF11174.8 KPI38741.1 - 0.0019 18.0 0.6 0.0032 17.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) Insulin_TMD PF17870.1 KPI38741.1 - 0.2 11.7 1.3 0.32 11.1 1.3 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TNFR_16_TM PF18422.1 KPI38741.1 - 1.7 8.7 5.0 0.91 9.5 2.2 1.9 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Shugoshin_C PF07557.11 KPI38741.1 - 4.6 7.1 9.1 0.16 11.8 1.2 2.6 2 0 0 2 2 2 0 Shugoshin C terminus P16-Arc PF04699.14 KPI38742.1 - 2.4e-29 102.8 0.0 2.8e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Acetyltransf_3 PF13302.7 KPI38743.1 - 1.1e-32 113.6 0.0 1.5e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain QCR10 PF09796.9 KPI38743.1 - 6.9e-27 93.3 1.5 1.2e-26 92.5 1.5 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Acetyltransf_1 PF00583.25 KPI38743.1 - 4.7e-07 30.1 0.0 7.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KPI38743.1 - 7e-07 29.0 0.1 7.3e-06 25.7 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KPI38743.1 - 0.0012 19.0 0.0 0.004 17.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI38743.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KPI38743.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Fe-ADH PF00465.19 KPI38744.1 - 3e-68 230.3 0.0 3.6e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPI38744.1 - 1.5e-05 24.8 0.1 0.00031 20.5 0.0 2.3 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase DUF4310 PF14187.6 KPI38744.1 - 0.15 11.7 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Abhydrolase_6 PF12697.7 KPI38745.1 - 1.5e-10 42.1 5.8 2.9e-10 41.1 5.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI38745.1 - 6.1e-09 35.5 0.0 9.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI38745.1 - 3.9e-05 23.4 0.0 0.00013 21.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Aldedh PF00171.22 KPI38746.1 - 1e-140 469.4 0.0 1.2e-140 469.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI38746.1 - 0.00027 20.5 0.0 0.06 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 KPI38746.1 - 0.0057 15.8 0.1 0.016 14.3 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1712 PF08217.11 KPI38747.1 - 1.4e-16 60.2 0.0 6e-12 44.9 0.0 3.0 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) Zn_clus PF00172.18 KPI38749.1 - 3.9e-09 36.5 10.4 6.2e-09 35.8 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI38749.1 - 0.017 13.9 0.4 0.027 13.3 0.4 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain RPE65 PF03055.15 KPI38750.1 - 3.8e-94 316.5 0.0 8.9e-94 315.3 0.0 1.6 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.11 KPI38750.1 - 0.032 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor Ribosomal_60s PF00428.19 KPI38751.1 - 1.9e-08 34.8 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cupin_2 PF07883.11 KPI38752.1 - 6.6e-06 25.7 0.7 5.7e-05 22.8 0.1 2.7 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KPI38752.1 - 0.00076 19.1 0.1 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Cupin ARD PF03079.14 KPI38752.1 - 0.14 12.3 0.1 0.22 11.7 0.1 1.3 1 1 0 1 1 1 0 ARD/ARD' family Glyco_transf_90 PF05686.12 KPI38753.1 - 2.7e-23 82.5 0.3 4e-23 82.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KPI38753.1 - 1.5e-05 25.3 0.0 3.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SF3b1 PF08920.10 KPI38753.1 - 0.045 14.3 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 IL3 PF02059.15 KPI38753.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Interleukin-3 MFS_1 PF07690.16 KPI38754.1 - 6.8e-40 137.1 34.2 9.3e-40 136.6 34.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI38754.1 - 8.7e-15 54.5 10.3 8.7e-15 54.5 10.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI38754.1 - 2.7e-08 32.7 2.3 2.7e-08 32.7 2.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SpoIIIAH PF12685.7 KPI38754.1 - 0.18 11.6 10.7 0.46 10.3 10.7 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4112 PF13430.6 KPI38754.1 - 1.7 9.0 4.0 1 9.7 0.1 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4112) S36_mt PF10937.8 KPI38754.1 - 2 10.0 4.4 3.8 9.1 4.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial DUF4820 PF16091.5 KPI38754.1 - 3.7 6.8 5.9 5.9 6.2 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3328 PF11807.8 KPI38755.1 - 4.6e-19 69.1 4.0 5.5e-19 68.8 2.5 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) RRM_1 PF00076.22 KPI38756.1 - 2.3e-09 36.9 0.0 5.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI38756.1 - 1.6e-06 28.0 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KPI38756.1 - 0.0038 17.0 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KPI38756.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Peptidase_M35 PF02102.15 KPI38757.1 - 4.5e-95 318.6 11.3 5.6e-95 318.3 11.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KPI38757.1 - 6.7e-43 146.7 3.6 1.1e-42 146.0 3.6 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase cNMP_binding PF00027.29 KPI38759.1 - 1e-33 115.2 0.0 3.2e-21 75.2 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 KPI38759.1 - 8.2e-32 110.8 11.0 2e-31 109.6 11.0 1.7 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein p450 PF00067.22 KPI38759.1 - 2.6e-25 89.1 0.0 8.2e-25 87.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.6 KPI38759.1 - 1.7e-05 24.5 5.4 2.6 8.3 0.1 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 KPI38759.1 - 3.7e-05 24.0 2.6 0.017 15.6 0.1 5.1 6 1 0 6 6 6 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KPI38759.1 - 0.00044 20.1 0.3 0.0014 18.5 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI38759.1 - 0.033 14.1 2.7 0.076 12.9 0.3 2.8 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 KPI38759.1 - 0.31 11.7 11.0 65 4.7 0.3 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat E1-E2_ATPase PF00122.20 KPI38762.1 - 6.8e-35 120.2 12.4 1.8e-28 99.3 0.0 3.3 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPI38762.1 - 8.8e-25 87.5 8.0 8.8e-25 87.5 8.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPI38762.1 - 7.8e-19 68.8 0.6 3.2e-14 53.7 0.0 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPI38762.1 - 3.3e-17 62.3 0.0 6.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPI38762.1 - 3.5e-17 61.8 0.0 6.7e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI38762.1 - 4e-05 23.5 0.3 0.0013 18.5 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PPP4R2 PF09184.11 KPI38763.1 - 6.4e-09 35.8 0.5 3.2e-08 33.5 0.5 2.1 1 1 0 1 1 1 1 PPP4R2 Cupin_8 PF13621.6 KPI38764.1 - 1.3e-23 84.0 0.0 1.7e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KPI38764.1 - 0.0019 18.6 0.0 0.0097 16.3 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KPI38764.1 - 0.0084 15.8 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 Cupin domain C2 PF00168.30 KPI38765.1 - 4.1e-66 219.8 0.0 9.9e-19 67.5 0.0 5.6 5 0 0 5 5 5 5 C2 domain ING PF12998.7 KPI38765.1 - 3.7e-13 49.9 4.7 8.4e-13 48.8 4.7 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding adh_short_C2 PF13561.6 KPI38766.1 - 1.6e-47 162.1 1.7 2.1e-47 161.6 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI38766.1 - 5.5e-43 146.7 2.2 6.2e-43 146.5 1.5 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI38766.1 - 1.5e-11 44.6 0.7 2.6e-11 43.8 0.7 1.4 1 0 0 1 1 1 1 KR domain ETC_C1_NDUFA5 PF04716.14 KPI38768.1 - 3.9e-22 77.8 7.5 3.9e-21 74.6 0.4 2.6 3 0 0 3 3 3 2 ETC complex I subunit conserved region Aldedh PF00171.22 KPI38769.1 - 3e-132 441.4 2.9 4.9e-85 285.8 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.16 KPI38771.1 - 3.6e-28 98.5 57.0 1.4e-14 53.8 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPI38771.1 - 0.0013 17.4 13.4 0.0013 17.4 13.4 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein Glyco_hydro_47 PF01532.20 KPI38772.1 - 4.3e-153 510.5 0.0 5e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Reticulon PF02453.17 KPI38773.1 - 7.8e-08 32.4 0.4 1.5e-07 31.5 0.4 1.4 1 0 0 1 1 1 1 Reticulon Abhydrolase_6 PF12697.7 KPI38774.1 - 3.1e-13 50.9 0.1 7.8e-13 49.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI38774.1 - 0.0065 16.0 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPI38774.1 - 0.014 14.6 0.1 0.34 10.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPI38774.1 - 0.023 14.5 0.1 0.039 13.8 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KPI38774.1 - 0.028 14.2 0.1 0.073 12.8 0.0 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI38774.1 - 0.044 13.4 0.0 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KPI38774.1 - 0.048 13.8 0.0 0.92 9.6 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain DUF2920 PF11144.8 KPI38774.1 - 0.063 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PE-PPE PF08237.11 KPI38774.1 - 0.065 12.8 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain ATP-synt_C PF00137.21 KPI38775.1 - 1.2e-11 44.8 13.7 1.2e-11 44.8 13.7 2.1 2 1 0 2 2 2 1 ATP synthase subunit C AhpC-TSA PF00578.21 KPI38776.1 - 2.5e-19 69.4 0.0 4.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI38776.1 - 5.4e-13 48.9 0.0 8.3e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Ras PF00071.22 KPI38777.1 - 4e-49 166.3 0.0 1.9e-48 164.1 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPI38777.1 - 2.4e-19 69.7 0.0 3.6e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KPI38777.1 - 0.0079 15.6 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 KPI38777.1 - 0.02 14.1 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KPI38777.1 - 0.086 12.7 0.8 0.49 10.3 0.0 2.4 2 2 0 2 2 2 0 RsgA GTPase 2OG-FeII_Oxy_2 PF13532.6 KPI38778.1 - 1.6e-12 48.0 0.0 1.4e-10 41.7 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KPI38778.1 - 0.0021 18.5 0.2 0.014 15.9 0.2 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.18 KPI38779.1 - 1.5e-27 96.4 30.7 8.3e-12 44.5 5.3 4.0 2 2 1 3 3 3 3 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KPI38781.1 - 5.8e-25 88.0 36.1 1.3e-24 86.8 31.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1190 PF06693.11 KPI38781.1 - 0.2 12.0 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) ubiquitin PF00240.23 KPI38782.1 - 8.2e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KPI38782.1 - 0.034 14.7 0.7 0.11 13.1 0.7 2.0 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain PfUIS3 PF11567.8 KPI38782.1 - 0.05 13.9 1.4 0.094 13.1 1.4 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein Hemocyanin_M PF00372.19 KPI38782.1 - 0.056 12.6 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain ALAD PF00490.21 KPI38783.1 - 9.9e-103 343.6 0.0 1.2e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-HC5HC2H_2 PF13832.6 KPI38784.1 - 3.7e-15 56.0 0.2 3.7e-15 56.0 0.2 3.9 3 0 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.18 KPI38784.1 - 1e-14 54.4 0.0 2.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KPI38784.1 - 5.9e-13 48.9 0.1 5.9e-13 48.9 0.1 4.5 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 KPI38784.1 - 3.1e-11 43.0 45.6 8.5e-07 28.8 5.5 5.4 5 0 0 5 5 5 2 PHD-finger PHD_2 PF13831.6 KPI38784.1 - 2.5e-08 33.3 4.0 2.5e-08 33.3 4.0 4.4 4 0 0 4 4 4 1 PHD-finger C1_1 PF00130.22 KPI38784.1 - 0.0029 17.5 1.1 0.0029 17.5 1.1 6.5 6 1 1 7 7 7 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 KPI38784.1 - 0.14 12.4 0.1 0.43 10.8 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain C1_2 PF03107.16 KPI38784.1 - 4 7.8 34.5 0.19 12.1 1.2 5.7 6 0 0 6 6 6 0 C1 domain ABC_membrane PF00664.23 KPI38785.1 - 1.1e-78 264.6 37.9 4e-40 138.2 11.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI38785.1 - 6.1e-62 208.1 0.0 3.1e-33 115.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI38785.1 - 5.2e-17 62.0 1.2 3.8e-05 23.2 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPI38785.1 - 2.7e-08 34.2 0.5 0.026 14.8 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_21 PF13304.6 KPI38785.1 - 3.8e-07 30.2 0.2 0.41 10.4 0.0 3.9 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KPI38785.1 - 4.2e-07 30.5 2.6 0.032 14.6 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 KPI38785.1 - 6.8e-07 28.9 0.9 0.00048 19.8 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPI38785.1 - 2e-06 27.8 0.0 0.022 14.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KPI38785.1 - 1.3e-05 24.3 0.3 0.039 12.8 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 KPI38785.1 - 2.1e-05 25.1 0.1 0.0079 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KPI38785.1 - 3.2e-05 23.8 0.0 0.06 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KPI38785.1 - 3.6e-05 24.2 1.4 4 7.9 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KPI38785.1 - 0.00027 20.7 0.4 1.7 8.4 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KPI38785.1 - 0.00033 20.3 0.2 0.5 9.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 KPI38785.1 - 0.0015 18.5 0.1 3.6 7.4 0.0 3.0 3 0 0 3 3 3 2 Rad17 P-loop domain SbcCD_C PF13558.6 KPI38785.1 - 0.0019 18.4 2.3 0.68 10.2 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KPI38785.1 - 0.002 18.7 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KPI38785.1 - 0.0026 17.7 0.1 5 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KPI38785.1 - 0.0046 16.5 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KPI38785.1 - 0.018 15.2 0.1 6.3 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPI38785.1 - 0.018 15.3 0.4 8.8 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPI38785.1 - 0.022 15.2 0.0 8.6 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KPI38785.1 - 0.042 13.9 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KPI38785.1 - 0.091 12.5 0.2 7.4 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KPI38785.1 - 0.12 12.1 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HMGL-like PF00682.19 KPI38786.1 - 6.4e-76 255.4 0.0 1.2e-75 254.5 0.0 1.4 2 0 0 2 2 2 1 HMGL-like DUF2985 PF11204.8 KPI38786.1 - 6.7e-37 125.5 1.9 6.7e-37 125.5 1.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) LeuA_dimer PF08502.10 KPI38786.1 - 8.7e-23 80.7 0.0 2.4e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain NUSAP PF16006.5 KPI38786.1 - 0.0017 18.2 0.1 0.0045 16.8 0.1 1.7 1 0 0 1 1 1 1 Nucleolar and spindle-associated protein AMP-binding PF00501.28 KPI38787.1 - 8e-46 156.5 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPI38787.1 - 7.7e-07 28.9 0.4 1.7e-06 27.9 0.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus CAP PF00188.26 KPI38788.1 - 7.9e-05 23.5 8.6 0.00019 22.2 0.0 2.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Zn_clus PF00172.18 KPI38789.1 - 1.3e-08 34.8 7.2 2e-08 34.2 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.15 KPI38792.1 - 6.1e-93 312.5 0.0 7.5e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3455 PF11937.8 KPI38794.1 - 9.4e-38 130.1 0.1 1.6e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KPI38794.1 - 3.5e-07 30.3 0.0 7.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) DPPIV_N PF00930.21 KPI38794.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Acyl_transf_3 PF01757.22 KPI38797.1 - 4.1e-26 91.8 28.0 5.5e-26 91.4 28.0 1.1 1 0 0 1 1 1 1 Acyltransferase family TrkA_TMD PF18613.1 KPI38797.1 - 0.67 9.4 5.9 0.35 10.3 1.4 2.4 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain Myb_DNA-binding PF00249.31 KPI38798.1 - 9.6e-13 48.1 0.0 1.1e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KPI38798.1 - 1.2e-05 25.1 0.1 3.5e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KPI38798.1 - 0.0014 18.8 0.2 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain adh_short PF00106.25 KPI38799.1 - 5.8e-40 136.8 0.0 8.7e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38799.1 - 1.2e-30 106.8 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38799.1 - 5.6e-07 29.6 0.0 1.5e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPI38799.1 - 0.004 16.2 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPI38799.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Hist_deacetyl PF00850.19 KPI38801.1 - 1.7e-78 264.2 0.1 2.8e-78 263.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Cupin_8 PF13621.6 KPI38803.1 - 6e-46 157.2 0.0 7.5e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KPI38803.1 - 0.042 13.3 0.2 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein JmjC PF02373.22 KPI38803.1 - 0.098 13.1 0.1 3.3 8.2 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase Amino_oxidase PF01593.24 KPI38805.1 - 4e-23 82.4 0.0 1.6e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI38805.1 - 6.8e-14 51.9 0.2 1.6e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI38805.1 - 1.6e-12 47.3 0.0 2.1e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI38805.1 - 2.2e-11 43.9 0.5 2.1e-10 40.7 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI38805.1 - 1.7e-08 34.0 3.4 5.4e-06 25.8 3.3 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KPI38805.1 - 2.9e-07 29.5 0.6 0.00033 19.5 1.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KPI38805.1 - 3.2e-06 26.8 2.7 1.4e-05 24.6 1.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI38805.1 - 1.7e-05 25.3 3.7 0.0041 17.7 1.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI38805.1 - 6.5e-05 22.0 3.5 0.069 12.0 1.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KPI38805.1 - 8.3e-05 22.0 0.6 0.001 18.4 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPI38805.1 - 0.00014 21.3 2.2 0.00051 19.4 1.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI38805.1 - 0.00084 18.6 0.5 0.0015 17.8 0.5 1.3 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 KPI38805.1 - 0.0016 17.4 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 2 MCRA family NAD_binding_9 PF13454.6 KPI38805.1 - 0.003 17.5 2.7 0.043 13.8 0.4 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI38805.1 - 0.0043 16.2 2.1 0.0082 15.2 0.7 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KPI38805.1 - 0.008 16.6 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.22 KPI38805.1 - 0.011 14.8 2.1 0.023 13.8 2.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 KPI38805.1 - 0.018 14.7 0.3 0.033 13.8 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KPI38805.1 - 0.059 12.9 0.4 0.18 11.4 0.2 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 KPI38805.1 - 0.15 11.6 0.2 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KPI38805.1 - 0.34 10.8 1.1 0.57 10.0 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KPI38806.1 - 1.7e-13 50.2 0.7 2.7e-13 49.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI38806.1 - 1.2e-05 25.4 14.7 2e-05 24.6 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.6 KPI38807.1 - 5e-14 52.3 1.3 1.4e-13 50.9 1.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CIA30 PF08547.12 KPI38808.1 - 1.3e-31 109.8 0.0 1.8e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) S1-P1_nuclease PF02265.16 KPI38809.1 - 2.2e-61 207.9 0.0 2.6e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Tyrosinase PF00264.20 KPI38810.1 - 1e-40 140.4 0.0 1.4e-40 140.0 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2408 PF10303.9 KPI38811.1 - 7e-46 156.1 3.1 4e-30 105.1 0.4 4.7 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Tropomyosin_1 PF12718.7 KPI38811.1 - 0.027 14.6 1.6 0.079 13.1 0.4 2.1 2 0 0 2 2 2 0 Tropomyosin like EzrA PF06160.12 KPI38811.1 - 0.036 12.3 1.9 0.1 10.8 0.1 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 KPI38811.1 - 0.062 13.7 4.2 5.8 7.4 0.3 4.4 3 1 1 4 4 4 0 Snapin/Pallidin Mistic PF11458.8 KPI38811.1 - 0.067 13.2 0.2 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Membrane-integrating protein Mistic KxDL PF10241.9 KPI38811.1 - 0.1 12.9 5.3 10 6.5 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein XhlA PF10779.9 KPI38811.1 - 0.11 12.7 8.6 0.63 10.3 0.4 3.5 3 0 0 3 3 3 0 Haemolysin XhlA Fib_alpha PF08702.10 KPI38811.1 - 0.12 12.5 2.9 17 5.6 0.0 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KPI38811.1 - 0.31 11.5 3.0 7.7 7.1 0.1 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1772 PF08592.11 KPI38812.1 - 0.0028 18.0 0.3 0.0051 17.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2721 PF11026.8 KPI38812.1 - 0.011 15.6 3.4 0.018 14.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) SUR7 PF06687.12 KPI38812.1 - 0.018 14.7 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family Zip PF02535.22 KPI38812.1 - 0.036 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4171 PF13775.6 KPI38812.1 - 0.042 14.3 9.0 0.094 13.2 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) TMEM100 PF16311.5 KPI38812.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Nucleoporin_C PF03177.14 KPI38813.1 - 1.8e-91 307.7 3.6 2.9e-91 307.1 3.6 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KPI38813.1 - 4.9e-38 131.0 0.0 7.1e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Oxygenase-NA PF09859.9 KPI38813.1 - 0.23 11.0 1.2 0.76 9.3 0.1 2.2 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA LANC_like PF05147.13 KPI38814.1 - 2.1e-19 69.3 0.0 9.3e-18 63.9 0.0 2.5 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein Bromo_coat PF01318.18 KPI38815.1 - 0.048 13.7 0.8 0.085 12.9 0.8 1.3 1 0 0 1 1 1 0 Bromovirus coat protein Na_Ca_ex PF01699.24 KPI38815.1 - 0.057 13.4 4.5 0.7 9.8 4.5 2.2 1 1 0 1 1 1 0 Sodium/calcium exchanger protein Abhydrolase_9_N PF15420.6 KPI38815.1 - 0.14 12.1 6.1 0.023 14.7 1.9 1.7 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Gram_pos_anchor PF00746.21 KPI38816.1 - 0.0055 16.6 1.0 0.0055 16.6 1.0 2.3 2 0 0 2 2 2 1 LPXTG cell wall anchor motif Herpes_LMP1 PF05297.11 KPI38817.1 - 6.9 5.7 7.3 7.6 5.6 7.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Mito_carr PF00153.27 KPI38818.1 - 3.7e-37 126.1 5.5 1.4e-13 50.5 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.19 KPI38819.1 - 5.3e-33 113.9 0.0 9.3e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KPI38819.1 - 0.0053 16.9 0.0 0.0076 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KPI38819.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Fungal_trans PF04082.18 KPI38820.1 - 8.3e-19 67.7 0.8 1.2e-18 67.1 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane_2 PF06472.15 KPI38821.1 - 2.4e-89 299.3 0.7 2.4e-89 299.3 0.7 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KPI38821.1 - 4.6e-15 56.3 0.0 3.7e-14 53.4 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 KPI38821.1 - 0.014 15.9 0.7 1.7 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KPI38821.1 - 0.04 14.3 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KPI38821.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KPI38821.1 - 0.19 11.5 0.7 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zn_clus PF00172.18 KPI38822.1 - 0.00038 20.5 6.4 0.00067 19.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 KPI38823.1 - 2.5e-08 33.9 0.2 3.5e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI38823.1 - 3.4e-06 26.9 0.1 1.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KPI38824.1 - 4.8e-21 75.4 0.0 6.7e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI38824.1 - 7.4e-08 32.3 2.7 6.3e-05 22.9 0.2 2.4 2 0 0 2 2 2 2 Peptidase dimerisation domain Zn_clus PF00172.18 KPI38825.1 - 1.5e-07 31.4 7.0 4.3e-07 30.0 7.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI38825.1 - 0.0096 14.8 0.2 0.015 14.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SBP_bac_5 PF00496.22 KPI38825.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Response_reg PF00072.24 KPI38826.1 - 3.1e-20 72.4 0.1 3.2e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 KPI38826.1 - 2.9e-06 27.8 0.2 5.5e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DBP PF12361.8 KPI38826.1 - 0.055 13.3 0.3 0.055 13.3 0.3 1.6 2 0 0 2 2 2 0 Duffy-antigen binding protein Gln-synt_C PF00120.24 KPI38827.1 - 2.5e-62 210.9 0.0 4e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KPI38827.1 - 6.1e-14 52.5 0.1 2.7e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase PAS_4 PF08448.10 KPI38828.1 - 1e-14 54.7 0.0 5e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 KPI38828.1 - 3.7e-08 33.3 1.1 1.2e-07 31.6 0.4 2.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KPI38828.1 - 1.3e-06 28.6 0.0 5.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KPI38828.1 - 2.4e-06 27.5 0.0 1.1e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KPI38828.1 - 3.1e-06 27.4 0.0 1.1e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KPI38828.1 - 8.4e-06 25.7 0.0 3.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 PAS domain GAF_3 PF13492.6 KPI38828.1 - 0.036 14.4 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 GAF domain GAF_2 PF13185.6 KPI38828.1 - 0.04 14.2 0.0 0.23 11.8 0.0 2.4 2 1 0 2 2 2 0 GAF domain MIF PF01187.18 KPI38829.1 - 4e-12 46.4 0.0 6.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Nic96 PF04097.14 KPI38831.1 - 4.3e-194 646.5 0.0 6.1e-194 646.0 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KPI38831.1 - 3.4e-14 53.4 103.0 1.9e-10 41.4 25.4 4.9 3 1 2 5 5 5 4 Nucleoporin FG repeat region Glyco_hydro_3_C PF01915.22 KPI38832.1 - 7.8e-34 117.4 0.0 1.2e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI38832.1 - 3.2e-26 92.5 0.0 1.9e-23 83.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI38832.1 - 5.9e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Amidase PF01425.21 KPI38833.1 - 2.3e-76 257.6 0.0 4.9e-76 256.5 0.0 1.5 1 1 0 1 1 1 1 Amidase PCI PF01399.27 KPI38834.1 - 2.5e-19 69.7 0.1 8.3e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KPI38834.1 - 9.3e-14 51.2 0.3 3.3e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Fer2 PF00111.27 KPI38834.1 - 2.4e-07 30.6 0.5 6.6e-07 29.2 0.5 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SET PF00856.28 KPI38835.1 - 5.5e-15 56.2 0.4 5.5e-15 56.2 0.4 4.0 4 3 0 4 4 4 1 SET domain AWS PF17907.1 KPI38835.1 - 3.6e-08 33.3 5.8 3.6e-08 33.3 5.8 2.0 2 0 0 2 2 2 1 AWS domain Sigma70_ner PF04546.13 KPI38835.1 - 0.47 10.3 15.8 0.58 10.0 7.1 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region SQS_PSY PF00494.19 KPI38836.1 - 4.6e-54 183.7 0.2 6.3e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_M24 PF00557.24 KPI38837.1 - 9.8e-43 146.3 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CCDC106 PF15794.5 KPI38837.1 - 0.19 11.4 3.0 0.31 10.7 3.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3074 PF11274.8 KPI38838.1 - 4.5e-59 199.5 2.3 1.4e-58 197.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Suppressor_APC PF11414.8 KPI38838.1 - 0.00082 19.4 0.9 0.00082 19.4 0.9 2.4 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein START PF01852.19 KPI38838.1 - 0.002 17.5 0.0 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 START domain FapA PF03961.13 KPI38838.1 - 0.19 10.3 15.4 0.28 9.8 15.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KPI38838.1 - 0.84 8.9 19.7 1.7 7.9 19.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_8 PF13855.6 KPI38841.1 - 9.4e-08 31.7 2.4 3.4e-07 29.9 2.4 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KPI38841.1 - 3.7e-06 27.2 8.4 4.4e-05 23.8 0.7 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF3433 PF11915.8 KPI38842.1 - 2.8e-30 104.6 14.2 6.2e-25 87.5 3.9 4.4 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) MadM PF03818.13 KPI38842.1 - 1.9 8.4 5.3 8.6 6.3 0.7 2.6 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Pyr_redox_3 PF13738.6 KPI38844.1 - 1.6e-07 30.9 0.0 0.021 14.1 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI38844.1 - 4e-07 30.2 0.0 1.2e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI38844.1 - 5.6e-07 29.0 0.0 9.4e-05 21.7 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPI38844.1 - 2.5e-06 26.2 0.2 2.2e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI38844.1 - 3.2e-05 23.3 0.0 0.0018 17.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI38844.1 - 0.0062 17.1 0.0 0.81 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOPA_dioxygen PF08883.11 KPI38845.1 - 5.8e-42 142.2 0.3 7.3e-42 141.9 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family CASP_C PF08172.12 KPI38846.1 - 9.9e-87 290.4 0.1 9.9e-87 290.4 0.1 3.5 3 1 1 4 4 4 1 CASP C terminal ZapB PF06005.12 KPI38846.1 - 0.0057 17.1 0.1 0.0057 17.1 0.1 7.3 3 1 0 3 3 3 1 Cell division protein ZapB ERM PF00769.19 KPI38846.1 - 0.0097 15.8 5.3 0.0097 15.8 5.3 4.0 4 1 0 4 4 4 1 Ezrin/radixin/moesin family NAD_binding_1 PF00175.21 KPI38846.1 - 5.3 7.7 6.4 3.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Fez1 PF06818.15 KPI38846.1 - 9.4 6.6 55.0 0.53 10.7 0.7 4.5 3 1 2 5 5 5 0 Fez1 UDG PF03167.19 KPI38847.1 - 1.3e-17 64.2 0.0 2.7e-17 63.2 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF1977 PF09320.11 KPI38848.1 - 2.2e-28 98.6 0.4 3.8e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KPI38848.1 - 1.1e-21 76.8 0.8 1.7e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain DUF5528 PF17666.1 KPI38848.1 - 0.46 10.4 1.8 0.44 10.5 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5528) SAP25 PF15476.6 KPI38849.1 - 0.021 14.5 1.7 0.032 13.9 1.7 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Coprogen_oxidas PF01218.18 KPI38851.1 - 3.7e-136 452.7 0.0 4.5e-136 452.4 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DIOX_N PF14226.6 KPI38852.1 - 1.2e-32 113.1 0.0 4.1e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI38852.1 - 1.9e-13 50.7 0.0 3.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cellulase PF00150.18 KPI38853.1 - 1.1e-18 67.7 2.8 1.5e-18 67.3 0.1 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) ADH_zinc_N PF00107.26 KPI38856.1 - 2.6e-30 105.1 0.7 4.9e-30 104.2 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI38856.1 - 5.6e-18 66.3 0.1 1.3e-17 65.1 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI38856.1 - 1.4e-07 31.4 0.0 7.1e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KPI38856.1 - 1.1e-05 24.8 0.3 1.7e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KPI38856.1 - 0.0048 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Tetraspanin PF00335.20 KPI38857.1 - 0.0026 17.5 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Tetraspanin family GFO_IDH_MocA PF01408.22 KPI38859.1 - 1.2e-22 81.0 0.2 2.8e-22 79.8 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI38859.1 - 2.1e-06 27.7 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KPI38859.1 - 0.005 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KPI38859.1 - 0.032 14.7 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding COX16 PF14138.6 KPI38860.1 - 9.7e-29 99.7 0.0 1.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 NAD_binding_1 PF00175.21 KPI38861.1 - 8.9e-27 93.9 0.0 4.7e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPI38861.1 - 1.5e-14 54.1 0.0 3.6e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KPI38861.1 - 0.0002 21.5 0.0 0.0032 17.6 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Cyt-b5 PF00173.28 KPI38862.1 - 2.3e-20 72.5 0.1 4.7e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain B12D PF06522.11 KPI38863.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Robl_LC7 PF03259.17 KPI38863.1 - 9.1 6.1 7.4 40 4.1 0.0 2.2 1 1 1 2 2 2 0 Roadblock/LC7 domain PyocinActivator PF11112.8 KPI38864.1 - 0.21 11.7 0.4 0.5 10.5 0.4 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN zf-C2H2_jaz PF12171.8 KPI38865.1 - 1.1e-07 32.0 3.8 1.1e-07 32.0 3.8 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KPI38865.1 - 0.0073 16.6 5.5 0.016 15.5 5.5 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPI38865.1 - 0.14 13.1 3.1 0.25 12.3 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPI38865.1 - 0.26 11.8 0.1 0.26 11.8 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 KPI38865.1 - 1.7 9.3 5.1 2.8 8.6 1.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type BAG PF02179.16 KPI38866.1 - 1.3e-10 41.5 0.0 2.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KPI38866.1 - 6.8e-07 29.0 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KPI38866.1 - 0.038 14.6 0.1 0.094 13.3 0.1 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KPI38866.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KPI38866.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KPI38866.1 - 0.26 11.3 0.2 1.6 8.8 0.2 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain VWA PF00092.28 KPI38867.1 - 1.7e-06 28.4 0.0 5.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPI38867.1 - 4.4e-05 24.1 0.0 0.00014 22.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain FAD_binding_3 PF01494.19 KPI38868.1 - 1.5e-50 172.4 0.0 2.3e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI38868.1 - 4.7e-06 26.0 0.0 9.4e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI38868.1 - 5e-06 25.9 0.4 0.0039 16.3 0.5 2.1 1 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KPI38868.1 - 0.00014 20.8 0.1 0.002 16.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KPI38868.1 - 0.00025 21.2 0.1 0.00065 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI38868.1 - 0.00059 19.5 0.3 0.012 15.2 0.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI38868.1 - 0.0029 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KPI38868.1 - 0.0041 16.5 0.2 0.017 14.5 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPI38868.1 - 0.025 13.4 0.2 4.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 KPI38868.1 - 0.047 12.8 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KPI38868.1 - 0.057 12.5 0.2 0.26 10.3 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPI38868.1 - 0.11 11.7 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI38868.1 - 0.16 12.5 0.0 1.4 9.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Clr5 PF14420.6 KPI38869.1 - 1.5e-15 57.1 0.9 3.1e-15 56.1 0.9 1.5 1 0 0 1 1 1 1 Clr5 domain DUF3712 PF12505.8 KPI38870.1 - 4.3e-10 39.9 0.2 8.6e-07 29.3 0.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KPI38870.1 - 2.8e-06 27.8 0.4 0.48 11.0 0.0 4.6 4 0 0 4 4 4 3 Late embryogenesis abundant protein CRC_subunit PF08624.10 KPI38871.1 - 1.3e-52 177.8 0.3 1.9e-52 177.2 0.3 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.19 KPI38871.1 - 1.3 9.1 8.3 4.5 7.5 8.3 2.0 1 0 0 1 1 1 0 AT hook motif Zn_clus PF00172.18 KPI38872.1 - 1.3e-06 28.4 10.5 2.5e-06 27.5 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.8 KPI38872.1 - 0.52 10.4 5.1 1.6 8.9 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) BOP1NT PF08145.12 KPI38873.1 - 4.1e-104 348.1 7.0 8.2e-104 347.1 7.0 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain Rad52_Rad22 PF04098.15 KPI38873.1 - 8.7e-51 171.9 0.0 1.3e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein WD40 PF00400.32 KPI38873.1 - 3.6e-18 65.6 6.3 9.8e-09 35.7 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38873.1 - 7.3e-05 23.0 0.0 0.0084 16.4 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 KPI38873.1 - 3.4 6.9 9.3 0.15 11.4 0.4 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Leo1 PF04004.13 KPI38874.1 - 3.2e-22 79.1 0.1 3.2e-22 79.1 0.1 2.2 2 1 0 2 2 2 1 Leo1-like protein EF-1_beta_acid PF10587.9 KPI38874.1 - 0.5 10.9 0.0 0.5 10.9 0.0 6.7 8 0 0 8 8 8 0 Eukaryotic elongation factor 1 beta central acidic region FBPase PF00316.20 KPI38875.1 - 2.7e-18 66.1 0.1 8e-18 64.6 0.1 1.7 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain mRNA_cap_enzyme PF01331.19 KPI38876.1 - 0.02 14.7 0.3 0.06 13.2 0.3 1.7 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain FAM176 PF14851.6 KPI38876.1 - 0.44 10.2 3.0 1 9.0 3.0 1.5 1 0 0 1 1 1 0 FAM176 family Bac_rhodopsin PF01036.18 KPI38877.1 - 1.8e-57 194.5 15.7 2.3e-57 194.1 15.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF21 PF01595.20 KPI38877.1 - 0.58 9.8 6.4 0.064 13.0 1.8 1.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain TssN PF17555.2 KPI38877.1 - 1.1 8.6 8.5 0.72 9.2 2.6 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN SHR3_chaperone PF08229.11 KPI38877.1 - 2.6 7.0 6.0 0.93 8.4 0.3 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 SID-1_RNA_chan PF13965.6 KPI38877.1 - 3 6.1 9.5 4.3 5.6 9.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UBM PF14377.6 KPI38878.1 - 1.7 8.2 4.1 0.77 9.3 0.6 2.0 2 0 0 2 2 2 0 Ubiquitin binding region Fungal_trans_2 PF11951.8 KPI38879.1 - 0.014 14.2 0.1 0.024 13.5 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain ADH_N PF08240.12 KPI38880.1 - 5.2e-23 81.0 0.1 1.1e-22 80.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI38880.1 - 4.3e-08 32.9 0.1 1.1e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ThiF PF00899.21 KPI38880.1 - 2.6e-05 23.7 1.8 4.3e-05 23.0 1.8 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KPI38880.1 - 0.052 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KPI38880.1 - 0.073 12.3 1.2 0.12 11.6 1.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lum_binding PF00677.17 KPI38880.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Lumazine binding domain Sacchrp_dh_NADP PF03435.18 KPI38880.1 - 0.096 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KPI38880.1 - 0.15 11.7 0.2 0.3 10.6 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SnoaL_4 PF13577.6 KPI38881.1 - 1.4e-26 93.1 0.4 2.1e-26 92.5 0.4 1.3 1 0 0 1 1 1 1 SnoaL-like domain DivIC PF04977.15 KPI38881.1 - 0.034 13.9 0.3 0.076 12.8 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator PAH PF02671.21 KPI38881.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.2 3 0 0 3 3 3 0 Paired amphipathic helix repeat zf-C3HC4_3 PF13920.6 KPI38884.1 - 1.3e-10 40.9 14.6 2.8e-10 39.9 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KPI38884.1 - 8.7e-05 22.1 0.0 0.00021 20.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MORN PF02493.20 KPI38884.1 - 0.0014 18.4 16.0 0.032 14.1 3.0 4.0 4 0 0 4 4 4 2 MORN repeat OKR_DC_1 PF01276.20 KPI38884.1 - 0.22 10.2 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Prok-RING_4 PF14447.6 KPI38884.1 - 0.41 10.5 19.5 0.031 14.1 13.9 2.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPI38884.1 - 3.4 7.7 17.0 7.2 6.7 17.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DSPc PF00782.20 KPI38886.1 - 5.5e-08 32.7 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPI38886.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ATP-grasp_4 PF13535.6 KPI38886.1 - 0.051 13.2 0.2 0.093 12.3 0.2 1.3 1 0 0 1 1 1 0 ATP-grasp domain Aconitase PF00330.20 KPI38887.1 - 1.6e-150 502.2 0.0 2e-150 501.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPI38887.1 - 5.6e-46 156.1 0.0 9.1e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KPI38887.1 - 0.18 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Zn_clus PF00172.18 KPI38888.1 - 0.11 12.6 8.4 0.25 11.5 8.4 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S7e PF01251.18 KPI38890.1 - 1.9e-79 265.7 0.1 2.2e-79 265.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Y_phosphatase PF00102.27 KPI38891.1 - 2.2e-39 135.4 0.4 3.3e-33 115.2 0.1 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KPI38891.1 - 7.8e-10 39.2 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Caldesmon PF02029.15 KPI38891.1 - 0.95 8.2 3.5 3.1 6.5 0.1 2.1 2 0 0 2 2 2 0 Caldesmon Aldedh PF00171.22 KPI38892.1 - 1.4e-148 495.3 0.1 1.7e-148 495.0 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KPI38893.1 - 0.00019 20.6 0.0 0.00035 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHHC PF01529.20 KPI38894.1 - 7.6e-28 97.3 8.7 7.6e-28 97.3 8.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM52 PF14979.6 KPI38895.1 - 0.075 12.9 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Transmembrane 52 MINDY_DUB PF04424.13 KPI38896.1 - 9.1e-22 77.3 0.0 1.4e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Amidase PF01425.21 KPI38897.1 - 4.6e-81 273.1 0.0 9.5e-81 272.0 0.0 1.5 1 1 0 1 1 1 1 Amidase bZIP_1 PF00170.21 KPI38898.1 - 0.00048 20.2 7.4 0.00048 20.2 7.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor Cep57_CLD_2 PF14197.6 KPI38898.1 - 0.0092 16.1 2.1 0.033 14.3 0.2 2.6 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 DUF4439 PF14530.6 KPI38898.1 - 0.059 14.1 0.1 24 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) Phlebovirus_NSM PF07246.11 KPI38898.1 - 0.061 12.7 0.5 0.088 12.2 0.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PRKG1_interact PF15898.5 KPI38898.1 - 0.094 13.6 5.0 0.21 12.5 2.4 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_Maf PF03131.17 KPI38898.1 - 0.63 10.6 8.5 0.54 10.8 4.9 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor adh_short PF00106.25 KPI38899.1 - 1.5e-30 106.1 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI38899.1 - 4.4e-24 85.3 0.0 6.9e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI38899.1 - 2.8e-05 24.1 0.0 5.3e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 KR domain WD40 PF00400.32 KPI38900.1 - 1.2e-41 139.9 12.0 1.3e-07 32.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38900.1 - 3.7e-12 46.4 0.2 0.028 14.7 0.1 5.3 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI38900.1 - 8.2e-05 21.7 0.0 0.3 10.0 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KPI38900.1 - 0.0028 16.5 0.2 1.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 KPI38900.1 - 0.018 14.4 0.0 3.1 7.1 0.0 2.8 2 1 0 3 3 3 0 WD40-like domain BTB PF00651.31 KPI38901.1 - 1.3e-09 38.3 0.1 0.00091 19.4 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain DndE PF08870.11 KPI38901.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA sulphur modification protein DndE DNAJ_related PF12339.8 KPI38901.1 - 0.24 11.6 2.2 0.71 10.1 0.1 2.3 2 0 0 2 2 2 0 DNA-J related protein Sugar_tr PF00083.24 KPI38902.1 - 3.1e-103 346.1 18.8 3.8e-103 345.8 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1768 PF08719.11 KPI38902.1 - 2.6e-45 154.6 0.0 4.1e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) MFS_1 PF07690.16 KPI38902.1 - 2.3e-16 59.6 23.9 2.3e-16 59.6 23.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 KPI38904.1 - 1.7e-29 103.1 0.0 2.1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI38904.1 - 3.8e-15 56.2 0.0 5.2e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI38904.1 - 1.3e-07 31.3 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI38904.1 - 0.0042 16.5 0.0 0.008 15.6 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KPI38904.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KPI38904.1 - 0.0076 16.7 0.0 0.033 14.6 0.0 1.9 1 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPI38904.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KPI38904.1 - 0.041 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KPI38904.1 - 0.048 12.8 0.0 0.087 11.9 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Septin PF00735.18 KPI38905.1 - 1e-35 123.4 0.0 4.4e-12 45.9 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 KPI38905.1 - 0.061 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Thioredoxin PF00085.20 KPI38906.1 - 5.9e-45 151.5 0.1 5e-23 81.1 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KPI38906.1 - 4.8e-09 36.4 0.0 0.13 12.1 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KPI38906.1 - 0.0094 16.0 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.6 KPI38906.1 - 1.7 8.5 4.0 5.3 6.8 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin HSP20 PF00011.21 KPI38907.1 - 4.5e-10 39.6 0.9 7.7e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KPI38907.1 - 0.037 13.6 0.0 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 HSP20-like domain found in ArsA Na_H_Exchanger PF00999.21 KPI38908.1 - 7.5e-55 186.3 49.4 1.1e-54 185.7 49.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_1 PF00515.28 KPI38909.1 - 2.6e-27 93.5 17.5 7.3e-08 31.9 0.4 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KPI38909.1 - 2.9e-26 89.4 20.0 2.1e-05 24.2 0.3 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KPI38909.1 - 2.3e-22 79.3 22.7 0.00052 20.5 0.2 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI38909.1 - 5e-20 70.9 19.5 9.6e-07 28.4 1.6 7.7 6 1 1 7 7 7 4 TPR repeat DnaJ PF00226.31 KPI38909.1 - 1.4e-19 70.0 1.7 1.4e-19 70.0 1.7 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 KPI38909.1 - 1.4e-17 62.3 9.7 0.0015 18.6 0.3 7.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KPI38909.1 - 1.6e-15 57.5 20.8 0.00056 20.5 2.5 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPI38909.1 - 3.6e-12 45.8 15.6 0.013 15.8 0.6 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPI38909.1 - 8.8e-12 44.8 14.8 0.72 10.8 0.3 7.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KPI38909.1 - 7.7e-10 38.1 15.0 0.031 14.3 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPI38909.1 - 2.4e-08 33.9 7.1 0.0079 16.3 0.2 5.3 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KPI38909.1 - 6.3e-08 32.8 19.3 0.03 14.6 2.1 6.9 4 3 3 7 7 7 5 Tetratricopeptide repeat BTAD PF03704.17 KPI38909.1 - 6.7e-08 33.1 6.4 0.1 13.0 0.5 4.4 3 2 2 5 5 5 3 Bacterial transcriptional activator domain TPR_6 PF13174.6 KPI38909.1 - 1.2e-05 25.6 17.0 4.9 8.0 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TOM20_plant PF06552.12 KPI38909.1 - 1.3e-05 25.0 1.2 0.0018 18.0 0.0 2.8 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 ANAPC3 PF12895.7 KPI38909.1 - 2.8e-05 24.2 8.5 0.0025 18.0 1.5 4.5 2 2 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KPI38909.1 - 5.5e-05 23.2 11.1 0.0059 16.7 0.2 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 KPI38909.1 - 0.0026 16.8 0.8 0.016 14.3 0.3 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) RPT PF13446.6 KPI38909.1 - 0.016 15.1 0.4 0.41 10.6 0.0 3.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein RPN7 PF10602.9 KPI38909.1 - 0.02 14.6 2.2 0.18 11.5 0.0 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 KPI38909.1 - 0.087 13.2 13.5 0.21 11.9 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF928 PF06051.12 KPI38909.1 - 0.28 11.0 2.4 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) TPR_10 PF13374.6 KPI38909.1 - 0.65 9.9 23.8 0.74 9.8 0.0 7.6 8 1 1 9 9 9 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KPI38909.1 - 1.2 9.5 9.9 33 4.9 0.3 4.4 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.18 KPI38909.1 - 3.7 7.7 7.0 22 5.2 0.7 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain ADH_zinc_N PF00107.26 KPI38910.1 - 2.4e-25 89.0 0.3 3.9e-25 88.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI38910.1 - 5.9e-23 80.8 1.5 8.8e-23 80.3 0.4 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI38910.1 - 4.9e-09 36.0 0.2 8e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI38910.1 - 5.6e-07 30.7 0.0 1.1e-06 29.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPI38910.1 - 2.5e-05 23.7 0.8 3.6e-05 23.2 0.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KPI38910.1 - 0.00062 19.4 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 KPI38910.1 - 0.0009 18.6 0.1 0.0031 16.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KPI38910.1 - 0.009 16.7 0.1 0.019 15.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPI38910.1 - 0.022 14.1 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KPI38910.1 - 0.023 14.8 0.1 0.04 14.0 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DapB_N PF01113.20 KPI38910.1 - 0.027 14.6 0.3 0.053 13.7 0.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KPI38910.1 - 0.05 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 KPI38911.1 - 7.9e-09 35.6 0.0 1.6e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI38911.1 - 1.9e-08 34.8 0.0 4.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI38911.1 - 0.00026 20.8 0.0 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI38911.1 - 0.00032 21.3 0.0 0.0011 19.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI38911.1 - 0.0005 20.8 0.0 0.0013 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF3425 PF11905.8 KPI38913.1 - 7.6e-10 38.8 2.7 1.6e-09 37.8 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Suppressor_APC PF11414.8 KPI38913.1 - 0.059 13.4 2.3 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Snf7 PF03357.21 KPI38913.1 - 0.93 9.1 5.2 3.8 7.1 0.9 2.3 2 0 0 2 2 2 0 Snf7 Myc_target_1 PF15179.6 KPI38914.1 - 9.8 6.0 14.7 0.046 13.6 2.3 2.5 2 1 1 3 3 3 0 Myc target protein 1 Dus PF01207.17 KPI38915.1 - 4.5e-55 186.9 0.0 1e-54 185.7 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) MJ1316 PF04457.12 KPI38915.1 - 9.8e-18 64.7 0.5 2.3e-17 63.5 0.5 1.6 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain DUF2856 PF11043.8 KPI38915.1 - 0.015 15.4 0.7 0.045 13.9 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2856) DUF5395 PF17373.2 KPI38915.1 - 0.061 14.0 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5395) Asp_Glu_race PF01177.22 KPI38916.1 - 2.7e-45 155.0 0.0 3e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DAO PF01266.24 KPI38917.1 - 3.5e-49 168.3 0.0 6.5e-49 167.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KPI38917.1 - 5.3e-45 152.4 0.0 9.6e-45 151.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KPI38917.1 - 9.2e-09 34.9 0.1 1.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPI38917.1 - 0.00031 20.2 0.2 0.00054 19.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI38917.1 - 0.0019 17.5 0.1 0.005 16.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI38917.1 - 0.0045 17.2 0.3 0.02 15.1 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI38917.1 - 0.0045 16.3 0.0 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI38917.1 - 0.019 14.0 0.1 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPI38917.1 - 0.026 14.4 0.2 0.057 13.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KPI38917.1 - 0.062 13.9 0.1 0.54 10.9 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI38917.1 - 0.15 10.8 0.2 0.25 10.0 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Velvet PF11754.8 KPI38918.1 - 2.1e-05 24.6 0.0 2.1e-05 24.6 0.0 5.2 3 2 1 4 4 3 2 Velvet factor Golgin_A5 PF09787.9 KPI38918.1 - 0.00039 20.0 51.9 0.0094 15.4 22.3 3.2 1 1 1 2 2 2 1 Golgin subfamily A member 5 GRAB PF10375.9 KPI38918.1 - 0.00093 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 GRIP-related Arf-binding domain T3SSipB PF16535.5 KPI38918.1 - 0.0031 18.0 2.6 0.0031 18.0 2.6 3.7 3 0 0 3 3 3 1 Type III cell invasion protein SipB HMMR_N PF15905.5 KPI38918.1 - 0.014 14.9 51.2 0.041 13.4 29.7 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 KPI38918.1 - 0.025 13.7 37.1 0.03 13.4 21.4 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KPI38918.1 - 0.03 13.2 51.1 0.068 12.0 12.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein HALZ PF02183.18 KPI38918.1 - 0.038 14.2 2.8 0.053 13.8 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fez1 PF06818.15 KPI38918.1 - 0.067 13.6 48.6 0.43 11.0 11.4 3.2 1 1 2 3 3 3 0 Fez1 Fib_alpha PF08702.10 KPI38918.1 - 0.067 13.4 28.7 2.1 8.5 4.0 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KPI38918.1 - 0.068 12.8 50.3 2.2 7.8 31.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KPI38918.1 - 0.12 12.4 24.7 0.13 12.3 7.1 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.11 KPI38918.1 - 0.18 10.6 52.4 1.1 8.1 24.0 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FAM184 PF15665.5 KPI38918.1 - 0.22 11.3 46.9 2.7 7.7 28.4 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 KPI38918.1 - 0.33 11.0 56.4 0.034 14.2 9.6 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KPI38918.1 - 0.45 10.6 36.8 0.53 10.4 3.9 5.6 2 2 2 4 4 4 0 TolA binding protein trimerisation DUF3584 PF12128.8 KPI38918.1 - 0.6 7.6 48.0 1.6 6.1 46.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KPI38918.1 - 1 9.4 29.9 0.22 11.6 6.1 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) FliJ PF02050.16 KPI38918.1 - 1.8 8.8 42.9 0.077 13.2 21.4 4.1 1 1 1 3 3 3 0 Flagellar FliJ protein SHE3 PF17078.5 KPI38918.1 - 2.8 7.6 39.1 0.72 9.5 11.1 3.3 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 KPI38918.1 - 2.9 7.2 43.5 0.31 10.3 17.9 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KPI38918.1 - 7 6.7 57.3 0.79 9.8 10.0 4.7 1 1 2 4 4 3 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 KPI38918.1 - 7.1 4.6 50.7 5.1 5.1 23.0 2.7 1 1 2 3 3 3 0 HOOK protein ApoO PF09769.9 KPI38918.1 - 7.9 6.5 15.3 12 5.9 0.1 4.7 2 2 2 4 4 4 0 Apolipoprotein O MAD PF05557.13 KPI38918.1 - 8.4 4.6 50.9 0.69 8.2 16.2 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4600 PF15372.6 KPI38918.1 - 9.8 6.6 30.4 5.5 7.4 13.3 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) Exo_endo_phos PF03372.23 KPI38919.1 - 2e-06 27.5 0.1 9.6e-06 25.3 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CN_hydrolase PF00795.22 KPI38920.1 - 1.9e-07 30.7 0.0 5.4e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase KH_1 PF00013.29 KPI38920.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 KH domain ELP6 PF09807.9 KPI38921.1 - 1.6e-16 60.5 0.1 2.2e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KPI38921.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.18 KPI38922.1 - 8.5e-10 38.1 0.2 8.5e-10 38.1 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain PS_Dcarbxylase PF02666.15 KPI38923.1 - 3e-77 258.7 0.0 1.9e-75 252.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KPI38923.1 - 0.011 15.5 0.5 0.021 14.7 0.5 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like Biotin_lipoyl PF00364.22 KPI38923.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme CIAPIN1 PF05093.13 KPI38924.1 - 2.3e-41 140.4 4.4 4.8e-41 139.3 4.4 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KPI38924.1 - 8.8e-39 132.8 0.0 1.3e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Sad1_UNC PF07738.13 KPI38925.1 - 2.2e-08 34.2 0.0 1.6e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal SKA1 PF07160.12 KPI38925.1 - 0.05 13.5 5.4 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Phage_H_T_join PF05521.11 KPI38925.1 - 0.15 12.6 0.8 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 Phage head-tail joining protein Nop14 PF04147.12 KPI38925.1 - 0.76 7.9 10.2 1.3 7.1 10.2 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KPI38925.1 - 1.1 7.5 7.1 1.5 7.0 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KPI38925.1 - 6.3 6.0 7.7 10 5.3 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 KPI38925.1 - 6.4 6.8 19.0 2.6 8.1 11.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein MoCF_biosynth PF00994.24 KPI38927.1 - 3.2e-24 85.2 0.0 1.6e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Probable molybdopterin binding domain CENP-S PF15630.6 KPI38928.1 - 4.1e-24 84.8 0.0 6.4e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KPI38928.1 - 7.3e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DnaJ PF00226.31 KPI38929.1 - 2.1e-14 53.4 0.7 2.1e-14 53.4 0.7 2.4 3 0 0 3 3 3 1 DnaJ domain Podoplanin PF05808.11 KPI38930.1 - 2.7e-07 30.8 0.2 4.1e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 KPI38930.1 - 0.00025 20.1 0.2 0.00033 19.6 0.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein GPI-anchored PF10342.9 KPI38930.1 - 0.00066 20.4 1.2 0.0024 18.6 1.2 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4690 PF15756.5 KPI38930.1 - 0.0015 19.1 0.0 0.0028 18.2 0.0 1.5 1 0 0 1 1 1 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 KPI38930.1 - 0.0016 18.4 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family BatD PF13584.6 KPI38930.1 - 0.002 17.0 0.0 0.019 13.8 0.0 1.9 2 0 0 2 2 2 1 Oxygen tolerance Amnionless PF14828.6 KPI38930.1 - 0.0027 16.6 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 KPI38930.1 - 0.0098 15.3 0.4 0.021 14.2 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KPI38930.1 - 0.013 16.3 0.0 0.029 15.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KPI38930.1 - 0.022 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SARAF PF06682.12 KPI38930.1 - 0.03 14.0 0.2 0.04 13.6 0.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MtrF PF09472.10 KPI38930.1 - 0.048 13.1 4.5 0.09 12.2 3.7 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CYYR1 PF10873.8 KPI38930.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 FTR1 PF03239.14 KPI38930.1 - 0.11 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family Trp_oprn_chp PF09534.10 KPI38930.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 KPI38930.1 - 0.98 9.4 4.2 2.4 8.2 4.2 1.7 1 1 0 1 1 1 0 LPXTG cell wall anchor motif RsfS PF02410.15 KPI38931.1 - 1.6e-11 44.5 0.0 9.8e-10 38.8 0.0 2.6 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation ABC_tran PF00005.27 KPI38933.1 - 6.5e-40 136.8 0.1 6.3e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KPI38933.1 - 5.6e-18 65.1 36.7 1.1e-09 37.8 9.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KPI38933.1 - 2.3e-14 53.9 0.3 0.00097 19.0 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI38933.1 - 1.6e-07 31.0 0.0 0.019 14.4 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPI38933.1 - 1.7e-05 25.4 0.1 0.087 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KPI38933.1 - 0.00053 19.7 1.3 0.11 12.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KPI38933.1 - 0.0013 18.5 1.7 0.77 9.4 0.3 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPI38933.1 - 0.0016 18.4 0.2 0.14 12.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MukB PF04310.12 KPI38933.1 - 0.0049 16.7 1.3 0.075 12.8 0.2 2.4 2 0 0 2 2 2 1 MukB N-terminal AAA_22 PF13401.6 KPI38933.1 - 0.0095 16.2 0.6 4.1 7.7 0.1 3.0 2 2 0 2 2 2 1 AAA domain DUF4162 PF13732.6 KPI38933.1 - 0.017 15.8 0.0 1.5 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_27 PF13514.6 KPI38933.1 - 0.018 14.7 0.1 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KPI38933.1 - 0.039 14.4 0.3 6.8 7.1 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 KPI38933.1 - 0.076 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 AIG1 family SRP54 PF00448.22 KPI38933.1 - 0.077 12.6 2.6 4.5 6.9 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KPI38933.1 - 0.23 10.0 0.1 16 4.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KPI38933.1 - 0.28 11.2 0.5 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KPI38933.1 - 0.4 10.8 1.1 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RecO_N PF11967.8 KPI38934.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal peroxidase PF00141.23 KPI38935.1 - 1.2e-21 77.5 0.1 1.8e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Glyoxalase PF00903.25 KPI38936.1 - 1.1e-07 32.0 0.0 1.4e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KPI38936.1 - 0.0003 20.7 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain LNS2 PF08235.13 KPI38937.1 - 5.4e-95 317.2 0.0 7.7e-95 316.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KPI38937.1 - 1.8e-41 140.2 0.0 3.6e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KPI38937.1 - 0.017 14.7 0.0 0.091 12.3 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PMT PF02366.18 KPI38937.1 - 0.051 13.2 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Presenilin PF01080.17 KPI38939.1 - 0.91 8.2 6.6 1.1 8.0 6.6 1.2 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 KPI38939.1 - 1.1 9.9 13.6 2 8.9 13.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3043 PF11241.8 KPI38939.1 - 1.4 9.0 14.9 2.2 8.3 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) ATP_bind_1 PF03029.17 KPI38940.1 - 1.3e-74 251.0 0.0 1.7e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KPI38940.1 - 0.00045 20.2 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KPI38940.1 - 0.012 14.6 0.3 0.024 13.6 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KPI38940.1 - 0.037 14.1 0.0 0.4 10.8 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KPI38940.1 - 0.087 12.1 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KPI38940.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KPI38940.1 - 1.6 9.2 4.0 0.49 10.8 0.6 1.9 2 0 0 2 2 2 0 AAA domain Ribonucleas_3_3 PF14622.6 KPI38941.1 - 1e-07 32.2 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KPI38941.1 - 0.00037 21.1 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Oxidored_molyb PF00174.19 KPI38942.1 - 1e-44 152.2 0.1 2.8e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KPI38942.1 - 8.4e-21 74.4 4.4 8.4e-21 74.4 4.4 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain ECH_1 PF00378.20 KPI38943.1 - 3.5e-32 111.7 0.0 8.6e-32 110.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI38943.1 - 1.1e-23 84.2 0.4 3.1e-22 79.5 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF3337 PF11816.8 KPI38944.1 - 3.6e-54 183.2 0.0 6.6e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KPI38944.1 - 6.7e-12 45.7 10.1 0.0044 17.8 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI38944.1 - 0.1 12.9 0.0 3.3 8.1 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PAT1 PF09770.9 KPI38945.1 - 0 1109.0 1.8 0 1108.8 1.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AglB_L1 PF18079.1 KPI38947.1 - 0.093 13.0 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain TFIID-31kDa PF02291.15 KPI38948.1 - 7.4e-39 132.6 0.0 1.3e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Lipase_3 PF01764.25 KPI38949.1 - 1e-24 87.0 0.1 8.1e-23 80.9 0.0 2.2 1 1 1 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 KPI38949.1 - 0.0021 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KPI38949.1 - 0.0051 17.5 0.5 0.0059 17.2 0.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI38949.1 - 0.032 13.5 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KPI38949.1 - 0.051 13.1 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cutinase PF01083.22 KPI38949.1 - 0.095 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase Rib_5-P_isom_A PF06026.14 KPI38950.1 - 3.9e-40 137.3 0.0 1.4e-39 135.4 0.0 1.7 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KPI38950.1 - 0.0074 16.2 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Abhydrolase_6 PF12697.7 KPI38951.1 - 3.4e-14 54.0 0.1 4.3e-14 53.7 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.22 KPI38952.1 - 2.4e-41 139.4 0.0 5.2e-16 58.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUDIX PF00293.28 KPI38952.1 - 1.7e-16 60.5 0.1 3.4e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain RRM_3 PF08777.11 KPI38952.1 - 0.0017 18.4 0.3 0.0081 16.2 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 KPI38952.1 - 0.0026 17.7 0.0 0.0096 15.9 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Acetyltransf_1 PF00583.25 KPI38952.1 - 0.0033 17.6 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KPI38952.1 - 0.0038 17.4 1.0 10 6.3 0.0 3.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain RRM_7 PF16367.5 KPI38952.1 - 0.02 15.0 0.1 0.31 11.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif Acetyltransf_7 PF13508.7 KPI38952.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tti2 PF10521.9 KPI38954.1 - 9.7e-51 173.0 2.3 1.3e-50 172.5 2.3 1.2 1 0 0 1 1 1 1 Tti2 family HEAT_EZ PF13513.6 KPI38954.1 - 0.063 13.8 0.3 15 6.2 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat DUF3701 PF12482.8 KPI38954.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage integrase protein WSC PF01822.19 KPI38955.1 - 4.6e-08 33.1 6.0 4.6e-08 33.1 6.0 2.1 2 0 0 2 2 2 1 WSC domain EphA2_TM PF14575.6 KPI38955.1 - 0.0063 17.4 0.0 0.018 15.9 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 KPI38955.1 - 0.022 15.2 0.0 0.022 15.2 0.0 3.5 3 1 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 TMEM51 PF15345.6 KPI38955.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 Syndecan PF01034.20 KPI38955.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain LST1 PF05083.13 KPI38955.1 - 0.092 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 LST-1 protein TMEM154 PF15102.6 KPI38955.1 - 0.81 9.6 0.0 0.81 9.6 0.0 3.4 2 1 1 3 3 3 0 TMEM154 protein family Cmc1 PF08583.10 KPI38956.1 - 5.4e-14 52.0 3.3 5.4e-14 52.0 3.3 2.2 1 1 2 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KPI38956.1 - 0.013 15.2 1.0 0.028 14.2 1.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KPI38956.1 - 0.013 15.5 0.5 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MFAP1 PF06991.11 KPI38956.1 - 0.016 15.1 7.7 0.019 14.8 7.7 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing p450 PF00067.22 KPI38957.1 - 3.1e-37 128.4 0.0 3.9e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5624 PF18538.1 KPI38957.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Arf PF00025.21 KPI38958.1 - 2.6e-62 209.3 0.3 3e-62 209.2 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KPI38958.1 - 1.2e-12 47.7 3.7 1.4e-07 31.0 1.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KPI38958.1 - 1.5e-11 44.6 0.0 2.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KPI38958.1 - 1.4e-09 37.6 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KPI38958.1 - 2.8e-08 33.5 0.0 3.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KPI38958.1 - 2.4e-07 30.8 0.0 3.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KPI38958.1 - 1.2e-06 28.0 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KPI38958.1 - 0.00018 21.1 0.0 0.0066 16.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KPI38958.1 - 0.028 14.0 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PPK2 PF03976.14 KPI38958.1 - 0.079 12.5 0.0 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) 6PF2K PF01591.18 KPI38958.1 - 0.14 11.5 0.1 0.32 10.3 0.1 1.6 1 1 0 2 2 2 0 6-phosphofructo-2-kinase FMN_red PF03358.15 KPI38959.1 - 3.2e-27 95.2 0.0 4.2e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KPI38959.1 - 4.4e-06 26.5 0.0 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Endosulfine PF04667.17 KPI38960.1 - 2.8e-28 97.9 0.2 4.4e-28 97.2 0.2 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Med3 PF11593.8 KPI38960.1 - 0.051 12.8 0.3 0.066 12.4 0.3 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_pol_A PF00476.20 KPI38961.1 - 2.3e-60 204.7 0.0 3.1e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DUF2388 PF09498.10 KPI38961.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) DUF1454 PF07305.12 KPI38961.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) MFS_1 PF07690.16 KPI38962.1 - 6.7e-34 117.3 65.7 1.4e-28 99.9 18.6 4.0 2 1 2 4 4 4 4 Major Facilitator Superfamily ICE2 PF08426.10 KPI38964.1 - 2.9e-141 471.3 5.8 3.3e-141 471.1 5.8 1.0 1 0 0 1 1 1 1 ICE2 DUF1361 PF07099.11 KPI38964.1 - 0.21 11.6 4.8 1.8 8.5 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1361) PolyA_pol_RNAbd PF12627.7 KPI38965.1 - 2.5e-06 27.1 0.0 6.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A PolyA_pol PF01743.20 KPI38966.1 - 8.2e-20 71.5 1.2 4.8e-19 69.0 1.2 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain DCP2 PF05026.13 KPI38967.1 - 1.2e-27 96.1 2.2 2e-27 95.3 2.2 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KPI38967.1 - 8.9e-18 64.6 0.0 2.1e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain SPO11_like PF03533.14 KPI38967.1 - 4.2e-05 23.5 0.6 0.13 12.4 0.3 3.2 2 0 0 2 2 2 2 SPO11 homologue CaiF_GrlA PF07180.11 KPI38968.1 - 0.063 13.2 0.2 0.17 11.9 0.0 1.8 2 1 0 2 2 2 0 CaiF/GrlA transcriptional regulator FAD_binding_4 PF01565.23 KPI38969.1 - 4.3e-10 39.5 0.0 4.8e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI38969.1 - 3.2e-06 27.1 0.3 7.9e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.18 KPI38970.1 - 8.9e-16 57.7 0.1 1.2e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3592 PF12158.8 KPI38971.1 - 0.035 14.2 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Aminotran_3 PF00202.21 KPI38972.1 - 3.6e-82 276.2 0.2 4.5e-82 275.9 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Syja_N PF02383.18 KPI38974.1 - 2.9e-78 263.4 0.2 5e-78 262.6 0.2 1.4 1 0 0 1 1 1 1 SacI homology domain RNase_P_Rpp14 PF01900.19 KPI38975.1 - 7.7e-33 112.8 0.0 1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Aldo_ket_red PF00248.21 KPI38976.1 - 9.4e-66 222.0 0.0 1.1e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.23 KPI38979.1 - 1.2e-72 244.6 0.0 1.8e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KPI38979.1 - 2.7e-22 78.5 0.0 6.3e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KPI38979.1 - 1.1e-13 51.5 0.0 2.2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KPI38979.1 - 3.8e-05 23.4 5.5 6.6e-05 22.7 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI38979.1 - 0.00018 21.3 9.5 0.00033 20.5 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI38979.1 - 0.00036 20.3 5.2 0.00085 19.1 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI38979.1 - 0.00066 19.6 8.4 0.0013 18.7 8.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPI38979.1 - 0.0015 18.8 8.2 0.0034 17.7 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain CUE PF02845.16 KPI38979.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KPI38979.1 - 0.012 15.4 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain zf-RING_5 PF14634.6 KPI38979.1 - 0.014 15.3 7.6 0.028 14.4 7.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Taq-exonuc PF09281.10 KPI38979.1 - 0.33 10.9 3.1 8.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Taq polymerase, exonuclease zf-C3HC4_4 PF15227.6 KPI38979.1 - 0.48 10.6 8.4 0.98 9.6 8.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KPI38979.1 - 2.2 8.2 7.6 9.9 6.1 7.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DAO PF01266.24 KPI38980.1 - 1.5e-33 116.8 0.2 1.8e-33 116.6 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI38980.1 - 0.00048 20.3 1.0 0.00086 19.5 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI38980.1 - 0.0017 17.7 0.3 0.0036 16.6 0.3 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI38980.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPI38980.1 - 0.036 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KPI38980.1 - 0.062 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI38980.1 - 0.33 10.0 1.7 0.52 9.3 1.1 1.5 1 1 0 1 1 1 0 FAD binding domain PhyH PF05721.13 KPI38981.1 - 3.1e-24 86.4 0.0 4.4e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HGWP PF03578.15 KPI38981.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 HGWP repeat Mlh1_C PF16413.5 KPI38982.1 - 3e-91 305.5 0.0 4.4e-91 305.0 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KPI38982.1 - 1.1e-32 112.3 0.0 3.1e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KPI38982.1 - 6.1e-12 45.5 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPI38982.1 - 2.5e-06 28.0 0.0 1.2e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5540 PF17694.1 KPI38982.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5540) Mito_carr PF00153.27 KPI38983.1 - 9.3e-41 137.7 9.0 6.3e-15 54.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2788 PF10981.8 KPI38984.1 - 0.004 17.1 0.3 0.01 15.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2788) PBP_N PF17093.5 KPI38984.1 - 0.0087 16.3 1.8 0.0087 16.3 1.8 1.6 2 0 0 2 2 2 1 Penicillin-binding protein N-terminus BCHF PF07284.11 KPI38984.1 - 0.033 14.2 0.2 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) RPT PF13446.6 KPI38984.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein Nop53 PF07767.11 KPI38986.1 - 4.6e-87 293.0 28.1 6.9e-87 292.4 28.1 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) LDB19 PF13002.7 KPI38987.1 - 1.7e-38 132.3 0.5 2.9e-38 131.5 0.5 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Ank_2 PF12796.7 KPI38988.1 - 4.8e-94 309.1 27.0 1e-16 61.3 0.3 11.5 4 2 9 13 13 13 12 Ankyrin repeats (3 copies) Ank PF00023.30 KPI38988.1 - 1.4e-68 224.5 16.5 8.1e-06 26.1 0.2 17.7 18 0 0 18 18 18 13 Ankyrin repeat Ank_4 PF13637.6 KPI38988.1 - 3.4e-67 222.0 7.0 4.6e-09 36.6 0.1 14.6 5 3 11 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI38988.1 - 1.8e-62 199.9 7.8 0.0024 18.2 0.0 19.3 19 0 0 19 19 18 13 Ankyrin repeat Ank_5 PF13857.6 KPI38988.1 - 4.1e-59 195.9 25.9 3e-11 43.3 1.1 14.7 6 5 10 16 16 16 11 Ankyrin repeats (many copies) NACHT PF05729.12 KPI38988.1 - 1.7e-08 34.5 0.0 5.7e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPI38988.1 - 2.2e-06 28.1 2.1 3.8e-06 27.4 0.4 2.3 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KPI38988.1 - 2.5e-05 24.6 0.0 0.00026 21.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KPI38988.1 - 2.7e-05 23.5 0.0 5.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KPI38988.1 - 0.002 18.2 0.0 0.13 12.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPI38988.1 - 0.0082 16.3 0.1 0.097 12.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 KPI38988.1 - 0.0096 16.3 0.1 0.066 13.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RVP PF00077.20 KPI38988.1 - 0.036 14.4 0.1 1.2 9.4 0.0 3.6 4 0 0 4 4 3 0 Retroviral aspartyl protease DUF5446 PF17522.2 KPI38988.1 - 0.038 14.2 0.8 0.43 10.8 0.3 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Viral_helicase1 PF01443.18 KPI38988.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CholecysA-Rec_N PF09193.10 KPI38988.1 - 9.6 6.3 6.1 17 5.5 0.2 4.1 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal fn3 PF00041.21 KPI38989.1 - 1.2e-07 32.0 0.1 3.1e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF5337 PF17272.2 KPI38989.1 - 0.066 13.1 1.7 0.14 12.0 1.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Pur_ac_phosph_N PF16656.5 KPI38989.1 - 0.14 12.8 1.9 0.32 11.6 0.0 2.6 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain FOXP-CC PF16159.5 KPI38990.1 - 0.011 16.3 1.5 0.22 12.2 0.1 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KPI38990.1 - 4.3 8.4 5.2 3.4 8.8 1.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger ATP-synt_C PF00137.21 KPI38991.1 - 5.7e-23 81.0 29.5 4.1e-13 49.4 7.3 2.8 3 0 0 3 3 3 2 ATP synthase subunit C TAD2 PF18521.1 KPI38992.1 - 7.1 6.8 8.6 44 4.3 2.0 3.3 1 1 0 2 2 2 0 Transactivation domain 2 Rhomboid PF01694.22 KPI38993.1 - 5.2e-22 78.5 8.9 8.8e-22 77.7 8.9 1.3 1 0 0 1 1 1 1 Rhomboid family Histone_HNS PF00816.21 KPI38993.1 - 0.018 15.9 6.8 0.042 14.7 6.8 1.6 1 0 0 1 1 1 0 H-NS histone family HET PF06985.11 KPI38994.1 - 6.6e-18 65.5 0.0 1.8e-17 64.0 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cofilin_ADF PF00241.20 KPI38997.1 - 1.1e-14 54.2 0.0 1.3e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Clr5 PF14420.6 KPI38998.1 - 1.5e-15 57.2 0.0 2.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Clr5 domain TPR_14 PF13428.6 KPI38998.1 - 0.07 14.0 0.7 15 6.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cupin_2 PF07883.11 KPI38999.1 - 6.9e-08 32.1 0.4 1.2e-07 31.3 0.4 1.5 1 0 0 1 1 1 1 Cupin domain TRIC PF05197.13 KPI38999.1 - 0.0011 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 TRIC channel AraC_binding PF02311.19 KPI38999.1 - 0.0019 18.1 0.2 0.0034 17.3 0.2 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain Git3 PF11710.8 KPI39000.1 - 4.3e-60 203.0 12.4 4.3e-60 203.0 12.4 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KPI39000.1 - 9.3e-25 86.5 1.4 2.3e-24 85.2 1.4 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KPI39000.1 - 3.4e-07 29.9 1.8 5.5e-07 29.2 1.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC_tran PF00005.27 KPI39001.1 - 4.3e-22 79.1 0.2 6.5e-10 39.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KPI39001.1 - 4.7e-07 29.9 1.6 0.0028 17.5 0.0 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPI39001.1 - 0.017 15.4 0.1 0.27 11.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KPI39001.1 - 0.021 15.1 0.1 0.92 9.8 0.1 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KPI39001.1 - 0.021 14.6 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KPI39001.1 - 0.021 14.5 0.1 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KPI39001.1 - 0.054 13.2 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KPI39001.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.6 KPI39001.1 - 0.15 12.6 0.4 0.28 11.7 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPI39001.1 - 0.15 12.4 0.3 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain RNase_H2_suC PF08615.11 KPI39003.1 - 5.8e-23 81.6 0.2 1.9e-22 79.9 0.2 1.7 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NUDIX_2 PF13869.6 KPI39004.1 - 1.3e-50 171.6 0.1 1.6e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase AAA PF00004.29 KPI39005.1 - 2.4e-97 322.4 0.0 3.7e-47 160.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI39005.1 - 7e-24 83.4 3.2 9.8e-13 47.7 0.5 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KPI39005.1 - 9.2e-19 67.4 0.4 2.7e-18 65.9 0.4 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KPI39005.1 - 2.5e-14 53.7 0.0 1.3e-07 31.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KPI39005.1 - 1.1e-13 51.2 0.0 1.8e-05 24.5 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPI39005.1 - 1.3e-12 48.0 0.0 2.3e-05 24.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KPI39005.1 - 3.7e-12 47.0 0.0 0.00014 22.3 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KPI39005.1 - 2.2e-10 40.6 0.6 0.0001 22.3 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KPI39005.1 - 2e-09 37.1 0.1 0.0019 17.5 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KPI39005.1 - 2.2e-09 37.7 0.2 0.025 14.9 0.0 4.2 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 KPI39005.1 - 3.8e-09 36.2 0.1 8.7e-09 35.0 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KPI39005.1 - 8.4e-08 31.8 0.3 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KPI39005.1 - 4.1e-07 30.6 0.0 0.031 14.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KPI39005.1 - 5.5e-07 29.9 0.0 0.025 14.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KPI39005.1 - 6.5e-07 29.2 0.1 0.028 14.1 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KPI39005.1 - 1.6e-06 28.2 0.0 0.019 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KPI39005.1 - 1.7e-06 27.6 0.2 0.52 9.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 KPI39005.1 - 5.2e-06 26.2 4.3 0.18 11.4 0.1 4.7 3 2 1 5 5 5 1 AAA domain AAA_7 PF12775.7 KPI39005.1 - 5.3e-06 26.1 0.1 0.03 13.8 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KPI39005.1 - 7.7e-06 25.2 0.0 0.0081 15.3 0.0 2.8 3 1 0 3 3 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KPI39005.1 - 8.1e-06 25.7 0.0 0.15 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KPI39005.1 - 1.6e-05 24.1 0.1 0.056 12.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KPI39005.1 - 3.8e-05 24.0 0.0 0.28 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 KPI39005.1 - 4.9e-05 23.3 0.0 0.2 11.5 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activat PF00158.26 KPI39005.1 - 5.4e-05 23.0 0.1 0.54 9.9 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KPI39005.1 - 5.9e-05 23.6 0.0 0.21 12.1 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Vps4_C PF09336.10 KPI39005.1 - 0.00011 22.1 1.2 0.0003 20.7 0.0 2.3 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 KPI39005.1 - 0.00018 21.9 0.0 0.67 10.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.6 KPI39005.1 - 0.00026 20.9 0.1 0.76 9.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain ResIII PF04851.15 KPI39005.1 - 0.00027 21.0 0.0 0.085 12.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KPI39005.1 - 0.00027 20.8 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KPI39005.1 - 0.00028 20.8 0.1 0.19 11.7 0.0 3.0 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.16 KPI39005.1 - 0.00029 20.4 0.4 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 KPI39005.1 - 0.0003 20.8 0.0 0.64 10.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KPI39005.1 - 0.00061 19.8 0.0 2.7 7.9 0.0 3.7 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KPI39005.1 - 0.0014 18.4 0.4 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KPI39005.1 - 0.0028 17.0 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UFD1 PF03152.14 KPI39005.1 - 0.0037 16.7 0.0 0.11 11.9 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 Viral_helicase1 PF01443.18 KPI39005.1 - 0.0041 16.9 0.0 0.36 10.5 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KPI39005.1 - 0.0061 16.9 1.0 6.3 7.1 0.0 3.4 3 1 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 KPI39005.1 - 0.0063 15.8 0.1 4.9 6.4 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin NB-ARC PF00931.22 KPI39005.1 - 0.0079 15.4 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.16 KPI39005.1 - 0.016 14.6 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 KPI39005.1 - 0.023 14.6 1.4 3.9 7.4 0.0 4.0 4 0 0 4 4 4 0 NTPase KAP_NTPase PF07693.14 KPI39005.1 - 0.041 13.1 0.3 3.1 7.0 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 KPI39005.1 - 0.043 13.9 0.0 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 KPI39005.1 - 0.055 13.1 0.0 2.3 7.8 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KPI39005.1 - 0.059 12.3 0.1 9.1 5.1 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KPI39005.1 - 0.067 12.9 0.0 11 5.7 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 KPI39005.1 - 0.082 11.9 0.0 3.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 KPI39005.1 - 0.093 11.6 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase eIF-1a PF01176.19 KPI39005.1 - 0.42 10.5 1.6 1.8 8.4 0.3 2.5 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 Aminotran_1_2 PF00155.21 KPI39006.1 - 8.4e-35 120.6 0.0 9.6e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1713 PF08213.11 KPI39008.1 - 6.3e-11 42.0 21.5 6.3e-11 42.0 21.5 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KPI39008.1 - 0.00016 22.4 0.2 0.00073 20.3 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial protein Pet20 EnY2 PF10163.9 KPI39009.1 - 0.00058 20.2 0.0 0.00099 19.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 MoeA_N PF03453.17 KPI39009.1 - 0.008 15.9 0.2 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) Met_10 PF02475.16 KPI39010.1 - 0.00033 20.5 0.0 0.00068 19.4 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein S1 PF00575.23 KPI39011.1 - 1.1e-72 240.3 27.6 8.6e-14 51.6 1.0 13.1 12 1 0 12 12 12 11 S1 RNA binding domain Suf PF05843.14 KPI39011.1 - 8.2e-09 35.9 19.8 1.8e-07 31.5 0.2 4.7 3 1 2 5 5 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KPI39011.1 - 1.7e-07 31.6 1.5 0.0013 19.2 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPI39011.1 - 8.1e-07 29.3 3.9 0.25 12.2 0.1 5.3 3 2 4 7 7 6 2 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KPI39011.1 - 2.7e-06 27.2 9.1 0.0081 16.1 0.3 6.3 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain TPR_15 PF13429.6 KPI39011.1 - 9.1e-05 21.8 2.7 0.00096 18.4 0.9 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPI39011.1 - 0.007 17.0 1.4 9.6 6.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPI39011.1 - 0.017 15.5 0.0 0.77 10.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat S1_2 PF13509.6 KPI39011.1 - 0.032 14.3 0.1 18 5.5 0.0 4.6 4 0 0 4 4 3 0 S1 domain TPR_12 PF13424.6 KPI39011.1 - 0.045 14.0 0.0 29 5.0 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KPI39011.1 - 0.047 12.8 0.0 3.6 6.6 0.0 3.1 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference PPR PF01535.20 KPI39011.1 - 0.05 13.9 0.2 3.8 8.0 0.0 3.5 4 0 0 4 4 3 0 PPR repeat PPR_2 PF13041.6 KPI39011.1 - 0.15 12.2 0.0 8 6.8 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family Pes-10 PF07149.11 KPI39011.1 - 2.3 7.2 10.1 4 6.4 10.1 1.3 1 0 0 1 1 1 0 Pes-10 F-box PF00646.33 KPI39012.1 - 4.3e-08 32.8 0.1 1.4e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPI39012.1 - 1.9e-06 27.7 0.1 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KPI39012.1 - 0.078 12.9 0.1 0.078 12.9 0.1 1.9 2 0 0 2 2 2 0 F-box DUF3369 PF11849.8 KPI39013.1 - 0.19 11.9 3.0 0.46 10.7 2.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3369) Pyr_redox_3 PF13738.6 KPI39014.1 - 1.2e-20 74.0 0.0 5.3e-19 68.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI39014.1 - 4.6e-19 68.8 0.2 3.3e-12 46.2 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPI39014.1 - 3.8e-18 65.2 0.0 4.1e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI39014.1 - 4.2e-15 55.8 0.0 3.3e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI39014.1 - 5.6e-10 39.3 3.6 0.002 17.8 0.2 3.9 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI39014.1 - 7.9e-08 32.4 1.2 0.061 13.3 0.0 4.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI39014.1 - 8.2e-07 29.2 0.0 4e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KPI39014.1 - 1.5e-06 27.7 0.0 1.3e-05 24.6 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KPI39014.1 - 8.1e-06 25.9 0.1 0.21 11.6 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KPI39014.1 - 4e-05 22.8 0.1 0.028 13.5 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 KPI39014.1 - 0.00013 21.2 0.3 0.5 9.4 0.0 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox PF00070.27 KPI39014.1 - 0.00014 22.4 0.3 0.76 10.4 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI39014.1 - 0.00043 19.1 0.1 0.0013 17.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KPI39014.1 - 0.00098 18.4 0.1 0.071 12.3 0.0 2.7 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.19 KPI39014.1 - 0.0011 18.3 0.1 0.59 9.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KPI39014.1 - 0.0013 19.2 2.5 0.51 10.9 0.5 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KPI39014.1 - 0.0022 18.2 0.1 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.18 KPI39014.1 - 0.0048 16.8 0.2 3.5 7.5 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KPI39014.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.12 KPI39014.1 - 0.0052 16.4 0.2 3.8 7.0 0.0 2.8 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 KPI39014.1 - 0.047 13.0 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 ThiF family DUF4147 PF13660.6 KPI39014.1 - 0.094 12.2 0.0 11 5.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4147) Amino_oxidase PF01593.24 KPI39014.1 - 0.11 11.8 0.0 19 4.4 0.0 3.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase ApbA PF02558.16 KPI39014.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.4 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF498 PF04430.14 KPI39014.1 - 0.15 12.2 0.0 14 5.8 0.0 3.0 4 0 0 4 4 2 0 Protein of unknown function (DUF498/DUF598) RRM_1 PF00076.22 KPI39015.1 - 5.4e-15 55.0 0.0 8.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPI39015.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KPI39015.1 - 0.04 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MatE PF01554.18 KPI39016.1 - 1.5e-58 197.0 13.6 2.5e-29 102.0 2.0 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KPI39016.1 - 0.00011 22.2 6.0 0.00011 22.2 6.0 3.6 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain CD225 PF04505.12 KPI39016.1 - 0.06 13.5 0.9 0.2 11.8 0.9 1.9 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF3742 PF12553.8 KPI39016.1 - 5.7 7.1 7.0 52 4.0 1.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) Prefoldin_2 PF01920.20 KPI39017.1 - 9.5e-18 64.1 8.6 1.2e-17 63.8 8.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Rootletin PF15035.6 KPI39017.1 - 0.007 16.4 5.2 0.014 15.4 0.1 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CCDC-167 PF15188.6 KPI39017.1 - 0.04 14.3 3.7 0.063 13.6 3.5 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fib_alpha PF08702.10 KPI39017.1 - 0.2 11.8 6.5 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2681 PF10883.8 KPI39017.1 - 0.51 10.8 7.3 0.65 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SlyX PF04102.12 KPI39017.1 - 0.83 10.3 7.7 5 7.8 0.1 2.3 2 0 0 2 2 2 0 SlyX YabA PF06156.13 KPI39017.1 - 1.3 9.7 6.6 0.94 10.1 0.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA XhlA PF10779.9 KPI39017.1 - 1.6 9.0 6.8 0.91 9.8 0.6 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Aldedh PF00171.22 KPI39018.1 - 1.9e-98 330.0 0.0 2.4e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SBP_bac_11 PF13531.6 KPI39020.1 - 0.0001 22.1 0.1 0.00013 21.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Collagen_mid PF15984.5 KPI39021.1 - 0.093 12.5 0.5 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial collagen, middle region LIP PF03583.14 KPI39021.1 - 0.19 11.0 0.2 0.46 9.8 0.2 1.6 2 0 0 2 2 2 0 Secretory lipase DNApol_Exo PF18136.1 KPI39022.1 - 2.4e-106 355.0 0.0 3.2e-106 354.6 0.0 1.1 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A_exo1 PF01612.20 KPI39022.1 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease ABC_tran PF00005.27 KPI39024.1 - 6.9e-42 143.2 0.1 2.1e-26 93.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KPI39024.1 - 8.1e-41 139.7 30.4 6.2e-26 91.1 9.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 KPI39024.1 - 1.5e-12 48.0 0.2 0.024 14.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPI39024.1 - 6e-09 36.0 1.6 0.00052 20.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KPI39024.1 - 3.7e-08 34.1 3.2 0.0042 17.6 0.2 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KPI39024.1 - 1.1e-07 31.6 2.4 0.55 9.6 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI39024.1 - 1.4e-07 31.2 4.8 0.005 16.5 1.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KPI39024.1 - 1.4e-07 32.0 0.9 0.0082 16.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KPI39024.1 - 5.2e-07 30.0 0.1 0.0067 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KPI39024.1 - 1.1e-06 29.0 0.2 0.071 13.4 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KPI39024.1 - 4e-05 23.3 4.3 0.015 14.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KPI39024.1 - 0.00022 21.0 0.7 0.12 12.1 0.3 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPI39024.1 - 0.00025 21.6 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KPI39024.1 - 0.00033 20.7 0.3 0.89 9.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KPI39024.1 - 0.00066 19.6 0.3 0.66 9.9 0.1 2.8 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 KPI39024.1 - 0.00068 19.8 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KPI39024.1 - 0.0023 17.6 0.6 0.92 9.1 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 KPI39024.1 - 0.0027 16.6 0.5 0.043 12.6 0.2 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Rad17 PF03215.15 KPI39024.1 - 0.0088 16.0 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KPI39024.1 - 0.012 16.0 0.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KPI39024.1 - 0.013 15.3 0.1 3.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KPI39024.1 - 0.013 14.6 0.4 2.8 6.9 0.4 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KPI39024.1 - 0.017 15.2 0.8 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KPI39024.1 - 0.017 15.3 0.0 6.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KPI39024.1 - 0.024 13.8 0.2 1.6 7.8 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KPI39024.1 - 0.025 14.5 1.1 2.9 7.8 0.1 3.3 4 0 0 4 4 3 0 NTPase AAA_17 PF13207.6 KPI39024.1 - 0.026 15.0 0.1 9.2 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KPI39024.1 - 0.033 14.5 0.3 1.7 9.0 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI39024.1 - 0.034 13.9 0.3 9.6 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KPI39024.1 - 0.038 13.7 0.1 27 4.5 0.1 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 KPI39024.1 - 0.04 13.6 1.1 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 KPI39024.1 - 0.054 13.4 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KPI39024.1 - 0.055 13.5 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KPI39024.1 - 0.064 13.3 0.2 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 KPI39024.1 - 0.11 11.8 0.2 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Septin IstB_IS21 PF01695.17 KPI39024.1 - 0.12 12.1 0.7 23 4.7 0.1 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 KPI39024.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KPI39024.1 - 0.14 12.2 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPI39024.1 - 0.17 11.2 0.3 2.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 KPI39024.1 - 0.23 11.3 0.2 2.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 KPI39024.1 - 0.25 10.5 0.1 20 4.2 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.12 KPI39024.1 - 0.28 10.6 1.0 1.9 7.9 0.2 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein PDR_assoc PF08370.11 KPI39024.1 - 0.32 10.8 1.9 0.44 10.3 0.1 2.1 2 0 0 2 2 1 0 Plant PDR ABC transporter associated FtsK_SpoIIIE PF01580.18 KPI39024.1 - 0.49 9.7 5.1 6.3 6.1 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family CTD PF12815.7 KPI39024.1 - 5.1 7.7 7.7 2.7 8.6 4.2 2.3 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 MFS_1 PF07690.16 KPI39025.1 - 5.9e-31 107.7 13.0 5.9e-31 107.7 13.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 KPI39025.1 - 5.3 7.1 9.9 4.4 7.4 1.4 2.6 2 0 0 2 2 2 0 Glycine zipper Roughex PF06020.11 KPI39026.1 - 0.75 8.8 3.7 1.4 7.9 3.7 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Ost4 PF10215.9 KPI39027.1 - 1.5e-18 66.3 3.0 2.3e-18 65.7 3.0 1.3 1 0 0 1 1 1 1 Oligosaccaryltransferase Pyr_redox_2 PF07992.14 KPI39028.1 - 1.4e-40 139.4 0.0 1.9e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI39028.1 - 5.4e-13 49.3 0.0 1.1e-10 41.9 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KPI39028.1 - 7.9e-06 25.1 0.1 2e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KPI39028.1 - 4e-05 23.2 0.2 0.00014 21.5 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KPI39028.1 - 0.0001 22.7 0.0 0.00031 21.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KPI39028.1 - 0.00083 18.7 0.4 0.0023 17.3 0.2 1.9 2 0 0 2 2 2 1 EF hand Costars PF14705.6 KPI39028.1 - 0.059 13.6 0.0 4.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Costars Surfac_D-trimer PF09006.11 KPI39028.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF1614 PF07758.11 KPI39029.1 - 0.044 13.8 0.6 0.061 13.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) UPF0160 PF03690.13 KPI39030.1 - 1.9e-123 412.1 0.0 2.2e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) PseudoU_synth_1 PF01416.20 KPI39030.1 - 0.03 14.8 0.0 0.081 13.4 0.0 1.7 2 0 0 2 2 2 0 tRNA pseudouridine synthase P5CR_dimer PF14748.6 KPI39031.1 - 7.7e-20 71.1 2.8 1.9e-19 69.8 2.8 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KPI39031.1 - 4.7e-14 52.7 1.1 9.9e-14 51.7 1.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KPI39031.1 - 1.4e-06 28.1 0.2 2.1e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPI39031.1 - 0.0062 16.6 0.2 0.013 15.5 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KPI39031.1 - 0.022 14.9 0.2 0.045 13.9 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KPI39031.1 - 0.16 12.2 2.1 0.22 11.8 0.2 2.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Mito_carr PF00153.27 KPI39032.1 - 2.8e-60 200.3 2.1 3.1e-24 84.7 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI39032.1 - 0.052 12.7 0.2 1.9 7.5 0.0 2.8 3 1 0 3 3 3 0 Gammaproteobacterial serine protease MFAP1 PF06991.11 KPI39033.1 - 9 6.1 9.1 0.81 9.5 4.4 1.6 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing CPSase_L_D2 PF02786.17 KPI39034.1 - 3.1e-113 376.5 0.3 1.5e-83 279.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KPI39034.1 - 4.4e-48 162.3 0.0 9.1e-48 161.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KPI39034.1 - 8.6e-47 159.4 0.0 1.9e-46 158.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KPI39034.1 - 8.9e-44 149.1 0.0 2.1e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KPI39034.1 - 2.1e-40 137.9 0.0 4.6e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KPI39034.1 - 1.5e-27 96.6 0.0 5.5e-27 94.8 0.0 2.1 2 0 0 2 2 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KPI39034.1 - 1.2e-20 73.9 0.6 2.3e-10 40.3 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 KPI39034.1 - 1.1e-17 64.0 0.0 4.4e-17 62.1 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KPI39034.1 - 8.1e-17 61.3 0.2 6.3e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KPI39034.1 - 7.3e-10 38.7 0.0 9.3e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KPI39034.1 - 4.8e-06 26.7 0.8 0.055 13.5 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 KPI39034.1 - 4.9e-06 26.5 0.6 0.00078 19.3 0.1 3.2 2 1 0 2 2 2 1 Peptidase C26 RimK PF08443.11 KPI39034.1 - 9.6e-05 22.1 0.0 0.3 10.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 KPI39034.1 - 0.00012 21.9 0.0 0.051 13.4 0.0 3.8 4 0 0 4 4 4 1 DJ-1/PfpI family GARS_A PF01071.19 KPI39034.1 - 0.0012 18.6 0.2 2.2 8.0 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ID PF18543.1 KPI39034.1 - 0.0027 17.7 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 Intracellular delivery domain zf-RING_2 PF13639.6 KPI39035.1 - 1.3e-06 28.7 2.5 0.014 15.8 0.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 KPI39035.1 - 0.0005 20.3 2.8 0.0016 18.7 2.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI39035.1 - 0.012 15.7 6.2 0.61 10.2 6.2 2.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KPI39035.1 - 0.012 15.3 6.0 0.25 11.1 0.4 2.6 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KPI39035.1 - 0.014 15.3 1.5 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI39035.1 - 0.015 15.2 2.5 1.6 8.8 0.1 2.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI39035.1 - 0.017 15.1 3.5 3.5 7.7 0.2 2.9 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI39035.1 - 0.019 14.8 3.3 0.69 9.8 0.2 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.9 KPI39035.1 - 0.045 13.0 1.0 0.07 12.4 1.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C3HC4_2 PF13923.6 KPI39035.1 - 4.4 7.2 7.1 3.1 7.7 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KPI39035.1 - 8.3 6.3 6.7 16 5.4 2.4 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Wyosine_form PF08608.12 KPI39036.1 - 6.4e-23 80.9 0.0 1.2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KPI39036.1 - 1.4e-12 48.3 0.0 2.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily RTA1 PF04479.13 KPI39037.1 - 1.4e-11 44.4 1.6 1.4e-11 44.4 1.6 1.6 1 1 0 1 1 1 1 RTA1 like protein DUF2976 PF11190.8 KPI39037.1 - 7.4 6.5 8.3 2.4 8.0 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) ADH_zinc_N PF00107.26 KPI39038.1 - 2.7e-27 95.3 0.0 3.9e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI39038.1 - 5.9e-19 69.4 0.0 9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI39038.1 - 2.2e-09 37.2 0.0 4.9e-07 29.6 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KPI39038.1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase CoA_trans PF01144.23 KPI39038.1 - 0.08 12.3 0.1 0.24 10.8 0.1 1.7 1 1 1 2 2 2 0 Coenzyme A transferase DUF1772 PF08592.11 KPI39039.1 - 1.8e-17 63.9 4.3 2.2e-17 63.6 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MscS_TM PF12794.7 KPI39039.1 - 0.0069 15.3 0.7 0.011 14.6 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 ISG65-75 PF11727.8 KPI39040.1 - 0.059 12.6 0.2 0.075 12.3 0.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein NMD3 PF04981.13 KPI39041.1 - 6.1e-80 268.2 4.2 8.9e-80 267.6 4.2 1.3 1 0 0 1 1 1 1 NMD3 family FAD_binding_1 PF00667.20 KPI39042.1 - 1.9e-68 230.4 0.0 2.7e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KPI39042.1 - 2.4e-37 128.3 0.4 4.6e-37 127.4 0.4 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KPI39042.1 - 5.2e-20 72.1 0.0 3.5e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Bromodomain PF00439.25 KPI39042.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.8 1 1 0 1 1 1 0 Bromodomain Ank_2 PF12796.7 KPI39043.1 - 1.7e-51 172.7 5.8 4e-15 56.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI39043.1 - 6.7e-37 125.4 9.1 6.7e-10 39.3 0.0 5.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI39043.1 - 2.6e-28 97.7 3.4 1.8e-07 31.3 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI39043.1 - 3.1e-24 82.4 0.1 0.00063 20.0 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KPI39043.1 - 6.7e-21 73.8 7.7 0.0069 16.8 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat DUF1843 PF08898.10 KPI39043.1 - 0.34 11.4 5.1 30 5.2 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) DUF2518 PF10726.9 KPI39044.1 - 0.14 11.8 0.6 3.8 7.2 0.0 2.9 2 1 1 3 3 3 0 Protein of function (DUF2518) SQS_PSY PF00494.19 KPI39045.1 - 1.6e-44 152.4 0.0 2.2e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase MFS_1 PF07690.16 KPI39046.1 - 1.9e-33 115.9 26.3 2.6e-33 115.4 26.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KPI39048.1 - 3.7e-41 141.2 0.1 1.6e-40 139.1 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI39048.1 - 0.00028 20.9 1.0 0.00054 20.0 1.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2271 PF10029.9 KPI39048.1 - 0.1 12.2 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) MFS_1 PF07690.16 KPI39049.1 - 8.8e-25 87.4 47.3 8.8e-25 87.4 47.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_Dp1 PF16938.5 KPI39049.1 - 2.1 8.6 5.4 3.3 8.0 1.6 3.0 2 0 0 2 2 2 0 Putative phage holin Dp-1 Pyr_redox_2 PF07992.14 KPI39051.1 - 1.8e-57 194.8 0.5 3.6e-57 193.8 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KPI39051.1 - 8.7e-26 90.3 0.3 1.5e-25 89.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KPI39051.1 - 1.1e-14 54.7 3.2 1.2e-14 54.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI39051.1 - 4.2e-08 32.8 0.1 4.2e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI39051.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KPI39051.1 - 0.051 12.9 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KPI39051.1 - 0.093 11.8 5.0 0.15 11.1 2.6 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI39051.1 - 0.19 10.8 5.3 5.3 6.0 2.0 2.5 3 0 0 3 3 3 0 FAD binding domain EF-hand_6 PF13405.6 KPI39052.1 - 9.9e-10 37.6 0.4 0.00099 18.9 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KPI39052.1 - 1.1e-06 29.0 0.3 1.1e-06 29.0 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KPI39052.1 - 0.00013 21.3 0.1 0.0063 16.0 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KPI39052.1 - 0.0038 17.0 1.2 0.068 13.0 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair Pkinase PF00069.25 KPI39053.1 - 4e-49 167.3 0.0 1.6e-48 165.4 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39053.1 - 5.7e-24 84.8 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI39053.1 - 0.0033 17.4 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPI39053.1 - 0.049 12.6 0.0 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KPI39053.1 - 0.12 11.7 0.0 0.48 9.7 0.0 2.0 3 0 0 3 3 3 0 Kinase-like PIP49_C PF12260.8 KPI39053.1 - 0.2 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Metallophos PF00149.28 KPI39055.1 - 8.7e-32 111.3 0.1 9.3e-23 81.8 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase DUF2075 PF09848.9 KPI39057.1 - 0.02 14.1 0.8 0.024 13.9 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 KPI39058.1 - 6.7e-10 39.4 10.0 0.013 16.4 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39058.1 - 0.0012 19.1 0.0 36 4.8 0.0 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KPI39058.1 - 0.11 11.6 0.1 0.23 10.5 0.1 1.5 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain TAXi_C PF14541.6 KPI39059.1 - 0.033 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RhoGEF PF00621.20 KPI39060.1 - 7.1e-10 39.4 0.1 1.5e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KPI39060.1 - 9.4e-07 28.7 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Zn_clus PF00172.18 KPI39061.1 - 5.9e-07 29.5 7.6 5.9e-07 29.5 7.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI39061.1 - 0.056 12.3 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_47 PF01532.20 KPI39062.1 - 1e-157 525.7 0.1 1.4e-157 525.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sugar_tr PF00083.24 KPI39063.1 - 2e-95 320.3 27.1 3e-95 319.7 27.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39063.1 - 7.7e-18 64.5 42.4 3.5e-13 49.2 19.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.18 KPI39065.1 - 6.6e-112 374.0 0.0 8.9e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KPI39065.1 - 6.2e-05 22.4 0.2 0.067 12.5 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KPI39065.1 - 0.00022 20.4 0.3 0.00032 19.8 0.3 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPI39065.1 - 0.00053 19.5 0.7 0.00078 18.9 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KPI39065.1 - 0.0021 17.2 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Npa1 PF11707.8 KPI39066.1 - 2.3e-74 250.8 0.0 4.3e-74 249.9 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KPI39066.1 - 2.1e-32 112.4 0.2 1.1e-31 110.0 0.1 2.4 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 HEAT PF02985.22 KPI39066.1 - 1.8 9.0 3.4 2.8 8.4 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat IF-2B PF01008.17 KPI39068.1 - 1.3e-59 201.7 0.0 2.5e-59 200.8 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF746 PF05344.11 KPI39068.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF2470 PF10615.9 KPI39069.1 - 2.9e-14 53.5 0.0 4.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) FAD_binding_3 PF01494.19 KPI39070.1 - 9.7e-23 81.0 1.0 3.1e-22 79.3 1.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI39070.1 - 6.4e-11 42.4 1.9 6.2e-09 35.9 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI39070.1 - 1.5e-09 37.9 0.6 8.3e-09 35.6 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI39070.1 - 3e-08 33.2 1.3 1.9e-05 24.0 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI39070.1 - 1.7e-07 31.7 0.1 4.6e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI39070.1 - 1.7e-07 30.7 0.5 1.6e-06 27.5 0.4 2.1 1 1 1 2 2 2 1 FAD binding domain ApbA PF02558.16 KPI39070.1 - 3.2e-05 23.6 0.4 6.9e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KPI39070.1 - 9.2e-05 21.5 1.1 0.044 12.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KPI39070.1 - 0.00041 19.5 0.5 0.00061 19.0 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KPI39070.1 - 0.0011 18.4 0.6 0.0015 17.9 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI39070.1 - 0.0034 16.7 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KPI39070.1 - 0.0091 15.3 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPI39070.1 - 0.012 14.4 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KPI39070.1 - 0.013 15.4 0.0 0.037 13.9 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KPI39070.1 - 0.016 14.3 0.5 0.027 13.5 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KPI39070.1 - 0.031 14.4 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KPI39070.1 - 0.041 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPI39070.1 - 0.066 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TSCPD PF12637.7 KPI39070.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 TSCPD domain UDPG_MGDP_dh_N PF03721.14 KPI39070.1 - 0.11 12.1 0.3 0.42 10.2 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Prenyltrans PF00432.21 KPI39070.1 - 0.15 11.8 0.4 0.29 10.9 0.4 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Smg4_UPF3 PF03467.15 KPI39071.1 - 2.1e-33 115.8 0.0 2.1e-33 115.8 0.0 2.7 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 KPI39071.1 - 4.4e-09 36.0 0.1 5.1e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAM PF15320.6 KPI39071.1 - 2 9.1 6.7 5.2 7.7 6.7 1.7 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Fungal_trans PF04082.18 KPI39072.1 - 2.5e-05 23.4 0.2 4e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KPI39072.1 - 0.019 13.8 0.3 0.053 12.3 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain RNA_Me_trans PF04252.13 KPI39073.1 - 2.5e-79 265.5 0.0 2.9e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Ribosomal_L11 PF00298.19 KPI39074.1 - 1.9e-28 98.8 0.6 3e-28 98.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KPI39074.1 - 9.8e-27 92.6 0.2 1.6e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 KPI39075.1 - 1.1e-31 110.2 0.0 3.5e-18 65.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39075.1 - 3.2e-12 46.3 0.0 1.1e-10 41.3 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 KPI39076.1 - 1.4e-34 119.6 28.8 1.5e-33 116.2 28.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Mannosyl_trans3 PF11051.8 KPI39077.1 - 3.2e-62 210.4 0.0 4e-61 206.8 0.0 2.6 2 1 0 2 2 2 1 Mannosyltransferase putative RR_TM4-6 PF06459.12 KPI39077.1 - 1.5 8.5 17.1 2.9 7.7 17.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Plasmodium_Vir PF05795.11 KPI39077.1 - 3.8 6.8 10.2 6.1 6.2 10.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein U79_P34 PF03064.16 KPI39077.1 - 4 6.7 17.9 7.3 5.9 17.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MAP7 PF05672.11 KPI39077.1 - 8.5 6.0 39.4 0.25 11.1 32.8 1.8 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family bZIP_1 PF00170.21 KPI39078.1 - 1.5e-06 28.2 7.7 1.5e-06 28.2 7.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KPI39078.1 - 7e-06 26.0 6.1 7e-06 26.0 6.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPI39078.1 - 0.0032 18.0 6.1 0.0032 18.0 6.1 2.4 3 0 0 3 3 3 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 KPI39078.1 - 0.53 9.6 4.6 0.93 8.8 4.6 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4045 PF13254.6 KPI39079.1 - 2.6e-100 337.0 43.3 2.6e-100 337.0 43.3 5.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KPI39079.1 - 2.7e-05 24.0 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 2 Gelsolin repeat Aminotran_3 PF00202.21 KPI39081.1 - 3.3e-38 131.4 0.0 2.1e-36 125.4 0.0 2.7 2 1 0 2 2 2 1 Aminotransferase class-III MIP PF00230.20 KPI39083.1 - 2.7e-24 86.1 4.7 1.1e-23 84.2 4.7 1.8 1 1 0 1 1 1 1 Major intrinsic protein XK-related PF09815.9 KPI39083.1 - 0.094 11.7 0.6 0.2 10.7 0.6 1.5 1 0 0 1 1 1 0 XK-related protein V-ATPase_H_N PF03224.14 KPI39084.1 - 4.3e-84 282.5 0.1 6e-84 282.0 0.1 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KPI39084.1 - 5.1e-38 129.8 0.2 1.3e-36 125.3 0.0 2.8 3 0 0 3 3 3 1 V-ATPase subunit H FANCI_S1 PF14675.6 KPI39084.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 FANCI solenoid 1 Ribosomal_L7Ae PF01248.26 KPI39085.1 - 3.5e-26 90.8 0.1 4.3e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KPI39085.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KPI39085.1 - 0.00029 20.9 0.0 0.0003 20.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 TMF_TATA_bd PF12325.8 KPI39086.1 - 1.2e-37 128.7 10.6 1.2e-37 128.7 10.6 6.8 2 1 5 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KPI39086.1 - 5.7e-10 39.1 11.6 5.7e-10 39.1 11.6 8.0 5 2 0 7 7 7 3 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KPI39086.1 - 2.8e-05 24.4 4.4 2.8e-05 24.4 4.4 5.2 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KPI39086.1 - 0.0073 15.2 0.6 0.0073 15.2 0.6 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF812) SlyX PF04102.12 KPI39086.1 - 0.054 14.1 0.8 0.054 14.1 0.8 9.3 3 3 7 10 10 10 0 SlyX Glyco_hydro_cc PF11790.8 KPI39088.1 - 2.6e-25 89.4 0.6 1.7e-17 63.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase catalytic core UPF0052 PF01933.18 KPI39089.1 - 2.2e-59 201.1 0.0 2.9e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 COA2 PF17051.5 KPI39090.1 - 0.0007 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 RNA_pol_Rpb1_6 PF04992.14 KPI39090.1 - 0.0082 16.0 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 F-box-like PF12937.7 KPI39092.1 - 1.9e-09 37.3 0.1 4.3e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI39092.1 - 4.9e-09 35.9 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Methyltransf_23 PF13489.6 KPI39092.1 - 0.014 15.2 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain F-box_4 PF15966.5 KPI39092.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box Methyltransf_32 PF13679.6 KPI39092.1 - 0.17 11.9 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UIM PF02809.20 KPI39092.1 - 1.7 8.7 13.8 0.96 9.5 1.1 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif AAA_19 PF13245.6 KPI39093.1 - 6.1e-11 42.9 0.1 1.2e-08 35.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KPI39093.1 - 8.1e-09 35.4 1.9 0.00014 21.5 0.2 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 KPI39093.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KPI39093.1 - 0.00023 21.0 0.1 0.0021 17.9 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI39093.1 - 0.00064 19.8 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KPI39093.1 - 0.0018 18.0 0.0 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 KPI39093.1 - 0.0092 15.4 0.0 0.045 13.1 0.0 1.9 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.17 KPI39093.1 - 0.025 14.7 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 Herpes_ori_bp PF02399.15 KPI39093.1 - 0.03 12.4 0.0 0.044 11.8 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein T2SSE PF00437.20 KPI39093.1 - 0.038 13.1 0.0 0.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Methyltransf_4 PF02390.17 KPI39093.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase AAA_24 PF13479.6 KPI39093.1 - 0.074 12.8 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KPI39093.1 - 0.092 12.5 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 KPI39093.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain YjeF_N PF03853.15 KPI39093.1 - 0.15 12.0 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus Fungal_trans_2 PF11951.8 KPI39094.1 - 2.4e-29 102.4 9.1 6.1e-29 101.0 9.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phe_hydrox_dim PF07976.12 KPI39094.1 - 0.049 13.7 0.6 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain SAM_3 PF18016.1 KPI39094.1 - 0.078 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Epimerase PF01370.21 KPI39096.1 - 2.2e-48 164.8 0.0 4.1e-48 163.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI39096.1 - 5.7e-43 147.6 0.0 1.5e-42 146.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI39096.1 - 1e-18 67.3 0.0 1.9e-18 66.5 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPI39096.1 - 7.5e-14 51.6 0.0 4.4e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KPI39096.1 - 1.2e-11 44.3 0.0 1.6e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPI39096.1 - 1.4e-08 34.2 0.1 3.8e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KPI39096.1 - 7.7e-08 32.4 0.0 1.8e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KPI39096.1 - 9.9e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KPI39096.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KPI39096.1 - 4.5e-05 23.1 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KPI39096.1 - 0.001 18.7 0.2 0.007 15.9 0.2 2.0 1 1 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KPI39096.1 - 0.025 14.2 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HET PF06985.11 KPI39097.1 - 3.7e-10 40.3 0.0 4.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PX PF00787.24 KPI39098.1 - 7.7e-16 58.1 0.4 2.4e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 PX domain Nucleoporin_FG PF13634.6 KPI39098.1 - 0.019 15.8 0.6 0.019 15.8 0.6 3.3 2 1 0 2 2 2 0 Nucleoporin FG repeat region Metallophos PF00149.28 KPI39099.1 - 9.1e-38 130.8 0.4 1.4e-37 130.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPI39099.1 - 0.041 14.3 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HET PF06985.11 KPI39100.1 - 6.4e-24 85.0 0.1 1e-23 84.3 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EMP24_GP25L PF01105.24 KPI39101.1 - 0.047 13.6 0.5 0.079 12.9 0.5 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2393 PF09624.10 KPI39101.1 - 3.8 7.5 5.2 0.84 9.6 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) CN_hydrolase PF00795.22 KPI39102.1 - 2e-16 60.1 0.0 1.6e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_17 PF00332.18 KPI39102.1 - 9.4e-09 35.3 0.3 2e-08 34.2 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 LRR_8 PF13855.6 KPI39103.1 - 5.7e-36 122.1 34.2 2.8e-07 30.2 0.3 10.2 7 3 4 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 KPI39103.1 - 5.2e-34 115.7 45.5 8.6e-07 29.2 1.9 11.0 7 2 8 15 15 15 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KPI39103.1 - 2.7e-11 42.4 41.4 4.4 8.2 0.0 15.0 15 2 0 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.6 KPI39103.1 - 3.1e-11 43.1 10.1 3.5e-05 23.4 0.2 4.3 2 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KPI39103.1 - 5.5e-10 38.5 42.3 0.6 10.3 0.3 13.0 16 0 0 16 16 16 5 Leucine Rich repeat LRR_5 PF13306.6 KPI39103.1 - 0.0019 18.2 0.2 2.3 8.2 0.1 3.5 2 2 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) Stealth_CR2 PF11380.8 KPI39104.1 - 4.7e-18 65.3 0.1 2e-17 63.3 0.1 2.0 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 KPI39104.1 - 7e-07 29.0 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 KPI39104.1 - 0.0034 17.3 0.0 0.008 16.1 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 DUF3445 PF11927.8 KPI39105.1 - 2.3e-72 243.3 0.0 3e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF4295 PF14128.6 KPI39105.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Ras PF00071.22 KPI39106.1 - 1.6e-59 200.1 0.1 1.9e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI39106.1 - 4.1e-21 75.4 0.0 5.9e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI39106.1 - 4.1e-08 32.9 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI39106.1 - 5.2e-06 26.1 0.1 3.8e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPI39106.1 - 0.00031 20.8 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI39106.1 - 0.0006 19.7 0.3 0.87 9.5 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KPI39106.1 - 0.009 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF2075 PF09848.9 KPI39106.1 - 0.12 11.6 0.4 6.1 6.0 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) fn3_PAP PF17808.1 KPI39106.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase ATP_bind_1 PF03029.17 KPI39106.1 - 0.59 9.9 2.0 4.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Peptidase_C12 PF01088.21 KPI39107.1 - 3.6e-56 190.2 0.0 4.4e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AAA_10 PF12846.7 KPI39109.1 - 0.0003 19.8 0.0 0.22 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.6 KPI39109.1 - 0.00091 19.5 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KPI39109.1 - 0.0098 16.3 0.1 0.071 13.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KPI39109.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 KPI39109.1 - 0.047 13.8 0.0 0.2 11.7 0.0 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain Metallophos PF00149.28 KPI39110.1 - 5e-33 115.3 0.0 1.3e-28 100.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KPI39110.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Flavodoxin_1 PF00258.25 KPI39111.1 - 1.4e-07 31.8 0.0 6.8e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin CMAS PF02353.20 KPI39113.1 - 1.4e-70 237.7 0.0 3.4e-70 236.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KPI39113.1 - 2.7e-10 40.8 0.0 5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39113.1 - 4.9e-08 33.5 0.0 8.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39113.1 - 3.2e-07 30.3 0.0 5.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI39113.1 - 1.5e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39113.1 - 0.0003 21.5 0.0 0.00061 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPI39113.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KPI39113.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Svf1_C PF17187.4 KPI39114.1 - 6.5e-56 188.7 0.1 1.1e-55 187.9 0.1 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KPI39114.1 - 4.5e-50 169.9 0.1 6.9e-50 169.3 0.1 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Isy1 PF06246.12 KPI39115.1 - 7.5e-74 248.5 8.6 1.1e-73 248.0 8.6 1.2 1 0 0 1 1 1 1 Isy1-like splicing family ECH_2 PF16113.5 KPI39116.1 - 7e-126 420.2 0.0 9.3e-126 419.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KPI39116.1 - 1.1e-26 93.6 0.0 2.8e-26 92.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Kei1 PF08552.11 KPI39117.1 - 9.6e-62 208.2 1.8 9.6e-62 208.2 1.8 1.5 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 KPI39117.1 - 0.15 12.1 6.1 0.14 12.3 3.5 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Dabb PF07876.12 KPI39119.1 - 5.5e-05 23.7 0.0 6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MOR2-PAG1_N PF14222.6 KPI39120.1 - 5.4e-166 553.8 0.0 8.7e-166 553.1 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KPI39120.1 - 4.2e-84 282.4 1.5 2.5e-83 279.8 0.0 2.6 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KPI39120.1 - 4.4e-27 94.2 8.9 7.4e-13 47.1 0.0 4.3 1 1 2 3 3 3 3 Cell morphogenesis central region Fungal_trans_2 PF11951.8 KPI39121.1 - 8.1e-06 24.9 0.0 3.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Borrelia_P83 PF05262.11 KPI39122.1 - 0.21 10.0 17.7 0.24 9.8 17.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_C37 PF05416.12 KPI39122.1 - 0.46 8.9 11.5 0.63 8.5 11.5 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase ATP-synt_C PF00137.21 KPI39124.1 - 1.5e-34 118.2 33.3 5.5e-22 77.9 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tetraspanin PF00335.20 KPI39124.1 - 4.9 6.8 6.8 7.4 6.2 6.8 1.2 1 0 0 1 1 1 0 Tetraspanin family AAA PF00004.29 KPI39125.1 - 8.3e-07 29.5 0.4 1.4e-05 25.5 0.4 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KPI39125.1 - 0.00032 20.7 0.0 0.0025 17.7 0.0 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KPI39125.1 - 0.0066 17.0 0.0 0.022 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPI39125.1 - 0.018 15.3 0.0 0.089 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KPI39125.1 - 0.07 13.5 0.3 0.42 11.0 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 KPI39125.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MFS_1 PF07690.16 KPI39129.1 - 1.9e-38 132.3 49.2 1.3e-36 126.3 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI39129.1 - 1.1e-14 54.1 9.4 1.1e-14 54.1 9.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI39129.1 - 0.0027 16.2 4.5 0.0044 15.5 4.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ThiF PF00899.21 KPI39130.1 - 6.9e-13 48.5 0.0 2.3e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 ThiF family AP_endonuc_2 PF01261.24 KPI39130.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Helo_like_N PF17111.5 KPI39131.1 - 1.7e-08 34.1 1.7 1.7e-08 34.1 1.7 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins IFT57 PF10498.9 KPI39131.1 - 0.0017 17.4 8.3 0.14 11.1 0.2 3.0 3 0 0 3 3 3 2 Intra-flagellar transport protein 57 SesA PF17107.5 KPI39131.1 - 0.0081 16.3 0.5 0.0081 16.3 0.5 2.2 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CENP-Q PF13094.6 KPI39131.1 - 0.34 11.1 10.4 0.056 13.6 5.6 1.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec2p PF06428.11 KPI39131.1 - 0.59 10.1 6.0 1 9.4 1.3 2.8 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p HisKA PF00512.25 KPI39131.1 - 5.7 7.1 8.8 0.26 11.3 0.7 2.9 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain SAM_2 PF07647.17 KPI39133.1 - 5e-18 65.0 0.0 8.1e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPI39133.1 - 3.9e-13 49.6 0.0 6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KPI39133.1 - 1.4e-09 38.5 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KPI39133.1 - 0.0098 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Myb_Cef PF11831.8 KPI39134.1 - 5.9e-29 101.3 8.5 5.9e-29 101.3 8.5 4.1 3 2 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KPI39134.1 - 1.1e-21 76.7 4.4 2.7e-11 43.5 0.8 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPI39134.1 - 1.3e-19 70.2 3.9 5.6e-13 48.9 1.5 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KPI39134.1 - 0.002 18.2 0.1 0.1 12.7 0.1 3.4 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain PIG-L PF02585.17 KPI39135.1 - 0.047 14.3 0.0 0.08 13.6 0.0 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Utp11 PF03998.13 KPI39136.1 - 5.2e-53 180.5 20.1 8.9e-53 179.7 20.1 1.4 1 1 0 1 1 1 1 Utp11 protein Syntaxin-6_N PF09177.11 KPI39136.1 - 0.049 14.2 1.7 0.14 12.7 1.7 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF4527 PF15030.6 KPI39136.1 - 0.14 11.6 8.6 0.022 14.2 5.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) F-box-like PF12937.7 KPI39137.1 - 0.015 15.2 0.0 0.089 12.7 0.0 2.3 2 1 0 2 2 2 0 F-box-like PI31_Prot_N PF11566.8 KPI39138.1 - 4.2e-47 160.0 0.0 5.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KPI39138.1 - 1.2e-17 64.9 18.8 1.2e-17 64.9 18.8 2.9 3 0 0 3 3 3 1 PI31 proteasome regulator Transglut_core PF01841.19 KPI39139.1 - 5.2e-12 46.2 0.0 1.2e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KPI39139.1 - 0.013 15.0 0.0 0.33 10.5 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain NfI_DNAbd_pre-N PF10524.9 KPI39139.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus zf-C3HC4_2 PF13923.6 KPI39140.1 - 0.23 11.4 7.5 0.36 10.7 7.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 KPI39140.1 - 4.2 5.1 5.5 4.7 4.9 5.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 MMR_HSR1 PF01926.23 KPI39141.1 - 7.3e-14 51.8 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI39141.1 - 4.2e-06 26.4 0.0 8.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 KPI39141.1 - 0.0037 16.6 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KPI39141.1 - 0.0037 17.2 0.9 0.013 15.4 0.9 1.9 1 1 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KPI39141.1 - 0.0059 17.1 0.1 0.099 13.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 KPI39141.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 KPI39141.1 - 0.024 15.0 0.1 0.04 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KPI39141.1 - 0.028 14.0 0.0 1.4 8.4 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KPI39141.1 - 0.044 13.8 0.4 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Dynamin family MCM PF00493.23 KPI39141.1 - 0.058 12.5 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain MeaB PF03308.16 KPI39141.1 - 0.076 12.0 0.0 0.66 8.9 0.0 2.1 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KPI39141.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI39141.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family SRPRB PF09439.10 KPI39141.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KPI39141.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PDZ_1 PF12812.7 KPI39142.1 - 0.089 12.8 0.8 1.5 8.9 0.1 2.4 2 0 0 2 2 2 0 PDZ-like domain Clr5 PF14420.6 KPI39144.1 - 1.2e-17 63.9 2.9 1.2e-17 63.9 2.9 1.8 2 0 0 2 2 2 1 Clr5 domain Cupin_1 PF00190.22 KPI39145.1 - 4.1e-11 42.7 0.1 6.7e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Cupin Mce4_CUP1 PF11887.8 KPI39146.1 - 0.11 11.9 2.0 0.2 11.1 1.1 1.6 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Swi5 PF07061.11 KPI39146.1 - 1.9 8.7 9.2 17 5.6 4.3 2.7 2 1 0 2 2 2 0 Swi5 MPS2 PF17060.5 KPI39146.1 - 3.9 6.6 6.8 5.8 6.1 6.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF5320 PF17253.2 KPI39146.1 - 4.7 8.3 6.3 1.9 9.6 0.8 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Oxidored-like PF09791.9 KPI39147.1 - 5.1e-23 80.5 3.8 5.1e-23 80.5 3.8 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KPI39147.1 - 0.035 14.0 3.3 0.09 12.8 3.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Acyl-CoA_dh_1 PF00441.24 KPI39148.1 - 7.2e-32 110.7 0.4 1e-31 110.2 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI39148.1 - 1.5e-25 90.0 0.0 5.9e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI39148.1 - 9.4e-24 83.5 0.1 1.5e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI39148.1 - 9.4e-07 29.2 0.2 2.4e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 KPI39149.1 - 9.3e-37 126.8 0.2 1.7e-36 125.9 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI39149.1 - 3e-36 124.7 0.2 4.6e-36 124.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI39149.1 - 8.5e-12 45.3 3.7 1e-09 38.6 3.7 2.1 1 1 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 KPI39149.1 - 0.012 15.6 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family AlaDh_PNT_C PF01262.21 KPI39149.1 - 0.016 14.5 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 KPI39149.1 - 0.054 13.5 0.2 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PRK PF00485.18 KPI39150.1 - 1.3e-52 178.4 0.0 1.8e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KPI39150.1 - 4.9e-38 130.7 0.0 7.9e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KPI39150.1 - 0.00011 22.8 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KPI39150.1 - 0.00075 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KPI39150.1 - 0.0021 18.2 0.0 0.0061 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KPI39150.1 - 0.03 14.7 0.0 15 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KPI39150.1 - 0.056 13.5 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KPI39150.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 KPI39150.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KPI39150.1 - 0.17 11.9 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KPI39150.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cpn10 PF00166.21 KPI39151.1 - 2.5e-28 98.0 0.0 2.9e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Ion_trans PF00520.31 KPI39152.1 - 3.4e-08 33.0 25.4 5.2e-08 32.4 25.4 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KPI39152.1 - 2.4e-05 23.2 20.3 0.00078 18.2 19.3 2.3 1 1 0 1 1 1 1 Polycystin cation channel DAO PF01266.24 KPI39153.1 - 1.1e-34 120.5 0.0 1.3e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI39153.1 - 5.7e-10 38.9 0.0 4.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI39153.1 - 4.8e-06 25.9 0.0 0.0024 17.0 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI39153.1 - 9.2e-06 25.0 0.1 0.063 12.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KPI39153.1 - 1.4e-05 25.2 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KPI39153.1 - 0.0017 17.7 0.1 0.0037 16.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KPI39153.1 - 0.0019 17.5 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KPI39153.1 - 0.0022 17.1 0.3 0.91 8.5 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KPI39153.1 - 0.0031 16.3 0.0 0.85 8.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KPI39153.1 - 0.0062 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI39153.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPI39153.1 - 0.015 15.8 0.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI39153.1 - 0.021 14.1 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI39153.1 - 0.027 13.3 0.4 0.21 10.4 0.4 2.0 1 1 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KPI39153.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 KPI39153.1 - 0.062 13.4 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPI39153.1 - 0.075 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KPI39153.1 - 0.082 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KPI39153.1 - 0.17 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mqo PF06039.15 KPI39153.1 - 0.24 9.9 0.0 0.73 8.3 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) AA_permease PF00324.21 KPI39154.1 - 4e-91 306.0 39.1 4.9e-91 305.7 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI39154.1 - 1.3e-21 76.9 43.7 1.7e-21 76.6 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 KPI39154.1 - 0.037 13.8 0.3 0.1 12.3 0.3 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 Amidase PF01425.21 KPI39155.1 - 2.7e-93 313.4 0.0 3.6e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Cupin_2 PF07883.11 KPI39156.1 - 1.2e-15 57.0 1.2 2.9e-15 55.7 0.8 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KPI39156.1 - 8.8e-06 25.7 0.2 1.3e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KPI39156.1 - 1.2e-05 24.9 0.1 4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KPI39156.1 - 0.0013 18.6 0.1 0.0016 18.3 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 KPI39156.1 - 0.0024 18.0 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like DMSP_lyase PF16867.5 KPI39156.1 - 0.0038 16.9 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 KPI39156.1 - 0.0074 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 KPI39156.1 - 0.083 12.6 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Auxin_BP PF02041.16 KPI39156.1 - 0.091 12.4 0.2 0.13 11.9 0.2 1.4 1 1 0 1 1 1 0 Auxin binding protein TrmE_N PF10396.9 KPI39157.1 - 5.1e-36 123.5 0.0 2.6e-35 121.2 0.0 2.3 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KPI39157.1 - 3.1e-22 79.8 0.0 1.5e-21 77.6 0.0 2.0 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KPI39157.1 - 4.6e-19 68.6 1.1 5.8e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KPI39157.1 - 5.6e-06 26.5 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KPI39157.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KPI39157.1 - 0.01 15.4 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPI39157.1 - 0.012 15.6 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KPI39157.1 - 0.012 16.1 0.0 0.12 12.9 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KPI39157.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KPI39157.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NUDE_C PF04880.13 KPI39157.1 - 0.72 10.3 10.4 1.7 9.1 9.1 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region CAP PF00188.26 KPI39158.1 - 1.3e-16 61.5 2.1 2.8e-16 60.5 2.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Methyltransf_25 PF13649.6 KPI39159.1 - 9.2e-18 64.7 0.0 2.3e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39159.1 - 8.9e-14 51.9 0.0 1.8e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39159.1 - 2.7e-13 50.0 0.0 3.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39159.1 - 3e-12 47.1 0.0 1.4e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.16 KPI39159.1 - 1.5e-10 40.8 0.0 1.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.6 KPI39159.1 - 5.2e-10 39.4 0.0 7.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI39159.1 - 1.7e-07 30.8 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPI39159.1 - 8.9e-06 25.3 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KPI39159.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain LemA PF04011.12 KPI39160.1 - 0.0067 16.3 7.4 0.0067 16.3 7.4 4.4 4 2 1 5 5 5 1 LemA family DUF1664 PF07889.12 KPI39160.1 - 0.012 15.7 30.8 0.02 14.9 2.3 5.4 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KPI39160.1 - 0.099 12.5 3.5 17 5.4 0.0 4.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Carbpep_Y_N PF05388.11 KPI39160.1 - 0.65 10.6 8.6 0.41 11.2 0.4 3.6 4 0 0 4 4 4 0 Carboxypeptidase Y pro-peptide GIT_CC PF16559.5 KPI39160.1 - 0.79 9.6 0.0 0.79 9.6 0.0 5.0 5 1 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nif11 PF07862.11 KPI39160.1 - 2 8.8 6.7 7.1 7.0 0.9 4.0 3 0 0 3 3 3 0 Nif11 domain AMP-binding_C_2 PF14535.6 KPI39160.1 - 7.4 7.0 8.9 0.22 11.8 0.7 2.8 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain GHMP_kinases_N PF00288.26 KPI39162.1 - 3.7e-14 52.7 2.7 1e-13 51.3 2.7 1.8 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPI39162.1 - 2.1e-05 24.8 0.0 7.5e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 GHMP kinases C terminal DUF3080 PF11279.8 KPI39162.1 - 0.0038 16.5 0.1 0.0066 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) GhoS PF11080.8 KPI39162.1 - 0.045 13.7 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Endoribonuclease GhoS Methyltransf_33 PF10017.9 KPI39163.1 - 1e-82 277.8 0.0 1.5e-82 277.3 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KPI39163.1 - 3e-10 40.1 0.1 6.1e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KPI39163.1 - 9.2e-05 23.0 0.9 0.00029 21.3 0.9 1.9 1 1 0 1 1 1 1 DinB superfamily ANAPC4_WD40 PF12894.7 KPI39164.1 - 0.001 19.3 0.0 2 8.8 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI39164.1 - 0.0017 19.1 0.0 0.12 13.3 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KPI39164.1 - 0.17 10.9 0.0 0.36 9.8 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region UvdE PF03851.14 KPI39166.1 - 1.2e-110 369.1 0.0 1.6e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE adh_short PF00106.25 KPI39167.1 - 1.2e-25 90.1 0.0 1.4e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39167.1 - 1.3e-19 70.8 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39167.1 - 0.0031 17.4 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF719 PF05334.13 KPI39168.1 - 0.048 13.9 3.9 0.086 13.0 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Med13_C PF06333.12 KPI39168.1 - 0.29 10.3 10.8 0.28 10.4 2.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain FSA_C PF10479.9 KPI39168.1 - 6 4.9 12.8 0.11 10.6 4.9 1.8 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus DDHD PF02862.17 KPI39169.1 - 2.3e-27 96.6 3.0 3.1e-15 57.0 0.0 3.5 2 1 1 3 3 3 2 DDHD domain Sugar_tr PF00083.24 KPI39170.1 - 1.6e-32 113.0 23.4 6.3e-21 74.7 7.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI39170.1 - 4.5e-16 58.7 37.4 5.7e-11 41.9 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thr_synth_N PF14821.6 KPI39171.1 - 1.4e-23 82.8 0.0 3.1e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KPI39171.1 - 1.2e-19 70.8 0.0 6.7e-19 68.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acyl-CoA_dh_1 PF00441.24 KPI39172.1 - 1.1e-15 58.2 0.7 1e-14 55.0 0.7 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI39172.1 - 4.4e-10 39.6 0.2 3.1e-09 36.9 0.2 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 KPI39172.1 - 8.1e-10 38.8 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain CHB_HEX_C PF03174.13 KPI39173.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF3112 PF11309.8 KPI39174.1 - 8.3e-11 41.7 6.9 9.6e-06 25.2 2.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) MMS1_N PF10433.9 KPI39176.1 - 6.8e-110 368.0 0.0 1.5e-109 366.8 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KPI39176.1 - 3.1e-54 184.5 0.0 2.3e-51 175.1 0.0 3.1 3 0 0 3 3 3 2 CPSF A subunit region ANAPC4_WD40 PF12894.7 KPI39176.1 - 0.079 13.3 0.1 3 8.2 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Mannosyl_trans3 PF11051.8 KPI39177.1 - 3.4e-32 111.9 0.0 2.3e-24 86.2 0.0 2.5 2 1 1 3 3 3 2 Mannosyltransferase putative ADH_N PF08240.12 KPI39178.1 - 6.5e-30 103.2 0.6 1.1e-29 102.5 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI39178.1 - 6.4e-16 58.5 1.0 2e-12 47.2 0.3 2.5 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI39178.1 - 0.00051 19.6 0.1 0.0026 17.3 0.1 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 KPI39178.1 - 0.044 14.3 0.2 0.85 10.2 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI39178.1 - 0.047 13.7 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KPI39178.1 - 0.091 12.2 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PH_10 PF15411.6 KPI39179.1 - 6.5e-32 110.4 0.0 1.8e-31 109.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KPI39179.1 - 1.9e-29 103.2 1.6 3.7e-29 102.2 1.6 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 KPI39179.1 - 2.4e-25 88.6 0.0 6.6e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 KPI39179.1 - 1.1e-05 25.2 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 KPI39179.1 - 0.0026 18.2 0.0 0.0066 16.9 0.0 1.6 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.16 KPI39180.1 - 1.8e-31 109.4 25.7 1.8e-31 109.4 25.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PP2C_2 PF13672.6 KPI39181.1 - 2.3e-06 27.4 0.5 6.2e-06 26.0 0.5 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KPI39181.1 - 0.033 14.1 0.2 0.17 11.8 0.0 2.3 3 1 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) AA_permease_2 PF13520.6 KPI39182.1 - 1.3e-51 175.8 49.5 1.7e-51 175.5 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI39182.1 - 1.7e-21 76.4 40.7 2.5e-21 75.9 40.7 1.2 1 0 0 1 1 1 1 Amino acid permease SART-1 PF03343.13 KPI39183.1 - 2.2e-05 23.3 0.0 3.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 SART-1 family NUDIX_2 PF13869.6 KPI39184.1 - 2.8e-11 43.4 0.0 3.1e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF948 PF06103.11 KPI39185.1 - 0.055 13.7 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MAP65_ASE1 PF03999.12 KPI39185.1 - 1.7 7.3 7.1 2.2 6.9 7.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Macoilin PF09726.9 KPI39185.1 - 9 4.7 7.5 10 4.5 7.5 1.1 1 0 0 1 1 1 0 Macoilin family RNase_T PF00929.24 KPI39187.1 - 2.5e-08 34.6 0.0 4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KPI39187.1 - 8e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DUF4611 PF15387.6 KPI39187.1 - 0.049 13.8 5.7 1.7 8.9 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CoaE PF01121.20 KPI39188.1 - 2.8e-38 131.4 0.0 3.4e-37 127.8 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KPI39188.1 - 0.031 14.8 0.3 3 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_L26 PF16906.5 KPI39189.1 - 2.6e-36 123.9 3.0 3.6e-36 123.5 3.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KPI39189.1 - 2.1e-07 30.7 0.3 6e-07 29.2 0.3 1.8 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KPI39189.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) GTP_EFTU_D2 PF03144.25 KPI39189.1 - 0.17 12.3 3.2 2.2 8.7 0.2 2.4 1 1 1 2 2 2 0 Elongation factor Tu domain 2 Glyco_transf_15 PF01793.16 KPI39190.1 - 9.1e-125 416.2 7.2 1.1e-124 416.0 7.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NDUF_C2 PF06374.11 KPI39190.1 - 0.3 11.2 2.0 17 5.6 0.3 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Rad60-SLD_2 PF13881.6 KPI39191.1 - 6.5e-12 45.5 0.0 1.6e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPI39191.1 - 0.00016 22.2 0.2 0.00034 21.1 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KPI39191.1 - 0.002 17.8 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ceramidase PF05875.12 KPI39194.1 - 1.4e-98 329.5 14.7 1.7e-98 329.3 14.7 1.0 1 0 0 1 1 1 1 Ceramidase Big_2 PF02368.18 KPI39194.1 - 0.25 11.3 0.5 0.42 10.5 0.5 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Beta-lactamase PF00144.24 KPI39196.1 - 3.4e-35 121.9 0.5 8.5e-35 120.5 0.5 1.5 1 1 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 KPI39197.1 - 7.2e-17 61.5 17.1 1.6e-05 25.6 0.3 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39197.1 - 2.2e-08 34.3 0.0 3.2e-05 24.1 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPI39197.1 - 0.0054 16.1 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain Ribonuclease_3 PF00636.26 KPI39198.1 - 2.4e-33 114.9 0.0 2.6e-15 56.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPI39198.1 - 4e-18 65.8 0.0 1.3e-07 31.8 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 KPI39198.1 - 5.3e-17 62.2 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI39198.1 - 4.3e-13 49.6 0.0 8.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 KPI39198.1 - 4.9e-12 45.9 0.0 3.5e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 KPI39198.1 - 2.4e-09 37.2 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KPI39198.1 - 0.01 15.1 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 KPI39199.1 - 3.6e-10 39.7 5.6 2.8e-09 36.8 2.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI39199.1 - 3e-09 36.6 8.9 5.4e-09 35.8 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI39199.1 - 1.3e-07 31.9 9.4 2.2e-07 31.1 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KPI39199.1 - 1.9e-07 31.1 3.8 2.4e-06 27.6 4.5 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KPI39199.1 - 3.3e-07 30.1 5.2 3.3e-06 26.9 5.8 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI39199.1 - 3.5e-07 30.1 8.6 6.1e-07 29.3 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPI39199.1 - 2.1e-06 27.5 9.8 6.8e-06 25.8 9.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI39199.1 - 0.004 17.0 9.7 0.038 13.9 9.7 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KPI39199.1 - 0.0054 16.6 3.3 0.14 12.0 1.8 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KPI39199.1 - 0.053 13.3 4.6 0.1 12.4 4.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KPI39199.1 - 0.067 13.2 5.8 0.25 11.4 5.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KPI39199.1 - 0.37 10.6 5.6 1.2 9.0 5.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Tmpp129 PF10272.9 KPI39199.1 - 1.1 8.5 5.1 1.6 7.9 5.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor FYVE PF01363.21 KPI39199.1 - 1.6 8.9 6.3 4.7 7.4 6.3 1.8 1 0 0 1 1 1 0 FYVE zinc finger Spem1 PF15670.5 KPI39199.1 - 2.8 7.4 10.2 0.7 9.4 5.8 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 FANCL_C PF11793.8 KPI39199.1 - 5 7.4 6.7 20 5.4 6.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zinc-ribbons_6 PF07191.12 KPI39199.1 - 8 6.5 6.5 1.8e+02 2.2 6.7 2.2 1 1 0 1 1 1 0 zinc-ribbons zf-RING_11 PF17123.5 KPI39199.1 - 8.2 6.3 11.2 1.5 8.6 7.1 1.9 2 0 0 2 2 2 0 RING-like zinc finger Uroplakin_II PF07353.12 KPI39200.1 - 0.0047 16.4 0.1 0.019 14.5 0.1 1.9 2 0 0 2 2 2 1 Uroplakin II Arginase PF00491.21 KPI39201.1 - 8.1e-89 297.8 0.0 9.6e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KPI39201.1 - 0.08 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain NHase_beta PF02211.15 KPI39202.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Peroxidase_2 PF01328.17 KPI39203.1 - 2.8e-41 142.1 0.0 4.7e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 MOZ_SAS PF01853.18 KPI39204.1 - 5.7e-76 254.2 0.0 9.2e-76 253.5 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 KPI39204.1 - 8.8e-22 76.8 0.0 2e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KPI39204.1 - 3.6e-09 36.1 1.9 2.8e-08 33.2 1.9 2.2 1 1 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KPI39204.1 - 0.00095 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI39204.1 - 0.0071 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Cas_Csy2 PF09614.10 KPI39204.1 - 0.082 12.2 0.6 0.62 9.4 0.3 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy2) F-box PF00646.33 KPI39205.1 - 0.0038 17.1 0.3 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPI39205.1 - 0.0049 16.7 1.0 0.014 15.3 0.1 2.2 3 0 0 3 3 3 1 F-box-like Utp12 PF04003.12 KPI39205.1 - 0.058 13.7 0.1 0.4 11.0 0.1 2.0 1 1 0 1 1 1 0 Dip2/Utp12 Family PRANC PF09372.10 KPI39205.1 - 0.063 13.6 0.9 0.24 11.7 0.3 2.2 2 1 0 2 2 2 0 PRANC domain DnaJ PF00226.31 KPI39206.1 - 8e-15 54.7 1.0 1.2e-14 54.1 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain Doppel PF11466.8 KPI39207.1 - 0.17 11.5 1.5 0.33 10.6 1.5 1.5 1 0 0 1 1 1 0 Prion-like protein Doppel TFIIA PF03153.13 KPI39207.1 - 0.98 9.3 17.2 1.3 9.0 17.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COesterase PF00135.28 KPI39208.1 - 8.8e-69 232.7 0.2 1.1e-61 209.3 0.4 2.7 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI39208.1 - 0.00091 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold GFA PF04828.14 KPI39208.1 - 0.017 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF2235 PF09994.9 KPI39209.1 - 8.1e-83 278.1 0.0 1.2e-82 277.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_1 PF00561.20 KPI39210.1 - 2.1e-18 66.9 0.0 5.3e-12 45.9 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI39210.1 - 1.9e-12 47.0 0.0 3.7e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI39210.1 - 1.3e-10 42.2 0.0 1.7e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KPI39210.1 - 7.1e-05 22.7 0.0 0.041 13.7 0.0 3.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KPI39210.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 KPI39210.1 - 0.014 14.1 0.0 0.14 10.8 0.0 2.0 1 1 0 1 1 1 0 Ndr family BAAT_C PF08840.11 KPI39210.1 - 0.15 11.9 0.0 5.5 6.8 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.16 KPI39212.1 - 1.2e-08 34.3 50.1 3.8e-07 29.4 49.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1418 PF07214.12 KPI39212.1 - 0.16 11.8 1.8 0.77 9.6 1.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) PEX11 PF05648.14 KPI39213.1 - 2.5e-51 174.3 0.5 3e-51 174.0 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Fungal_trans PF04082.18 KPI39215.1 - 7.5e-27 94.0 0.0 1.3e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_15 PF13429.6 KPI39215.1 - 0.095 11.9 1.7 0.11 11.6 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_B_thumb PF14791.6 KPI39217.1 - 8.6e-22 77.1 0.7 2e-21 75.9 0.7 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KPI39217.1 - 6.7e-19 67.5 0.3 1.5e-18 66.4 0.3 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KPI39217.1 - 7.2e-15 55.2 0.4 1.2e-13 51.3 0.4 2.4 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KPI39217.1 - 2.2e-06 27.9 0.0 6.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 KPI39217.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 KPI39217.1 - 0.082 13.5 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain FAD_binding_3 PF01494.19 KPI39218.1 - 7.7e-19 68.1 0.0 1.3e-18 67.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI39218.1 - 2.8e-08 33.7 0.7 0.0016 18.1 0.7 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI39218.1 - 1.2e-06 28.0 0.0 0.0012 18.2 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI39218.1 - 3.3e-06 26.5 0.3 5.2e-06 25.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI39218.1 - 1.1e-05 25.6 0.6 5.9e-05 23.2 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPI39218.1 - 0.00011 21.1 0.1 0.00035 19.4 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPI39218.1 - 0.00061 19.2 0.4 0.00087 18.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI39218.1 - 0.0017 18.9 0.1 0.04 14.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI39218.1 - 0.002 17.3 0.2 0.0035 16.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPI39218.1 - 0.0038 16.1 0.1 0.0088 14.9 0.1 1.6 1 1 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KPI39218.1 - 0.0066 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KPI39218.1 - 0.011 14.9 0.0 0.025 13.6 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 KPI39218.1 - 0.031 13.6 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KPI39218.1 - 0.064 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 KPI39220.1 - 0.00021 21.9 0.0 0.00032 21.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KPI39220.1 - 0.13 12.1 0.1 0.41 10.4 0.1 1.9 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase GTP_EFTU PF00009.27 KPI39221.1 - 3.3e-11 43.1 0.0 5.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPI39221.1 - 0.0015 18.5 0.4 0.51 10.2 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KPI39221.1 - 0.016 15.6 0.4 0.043 14.2 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain CTD_bind PF04818.13 KPI39222.1 - 1.4e-18 67.4 0.0 4.2e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Fungal_trans_2 PF11951.8 KPI39223.1 - 5.6e-13 48.4 7.8 2.5e-12 46.3 7.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 KPI39224.1 - 4.8e-06 26.3 0.1 1.2e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPI39224.1 - 0.0002 21.2 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Peptidase_M19 PF01244.21 KPI39225.1 - 7.7e-104 347.3 0.0 1.4e-103 346.4 0.0 1.4 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF2274 PF10038.9 KPI39227.1 - 0.054 14.0 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) Ysc84 PF04366.12 KPI39228.1 - 5.3e-40 136.1 0.4 8.1e-40 135.5 0.4 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KPI39228.1 - 4.1e-15 55.1 0.2 1.4e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KPI39228.1 - 3e-14 52.4 0.2 1.4e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KPI39228.1 - 4.8e-11 42.3 0.0 8.2e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Acylphosphatase PF00708.18 KPI39229.1 - 1.7e-26 92.4 0.4 1.9e-26 92.3 0.4 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF2871 PF11070.8 KPI39229.1 - 0.081 13.2 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) DLH PF01738.18 KPI39231.1 - 4.2e-15 55.9 0.0 2e-07 30.8 0.0 2.8 2 1 0 2 2 2 2 Dienelactone hydrolase family NAD_binding_1 PF00175.21 KPI39232.1 - 2.5e-12 47.4 0.0 3.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Helicase_IV_N PF12462.8 KPI39232.1 - 0.054 13.4 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DUF2040 PF09745.9 KPI39233.1 - 1.1e-34 119.0 15.1 1.1e-34 119.0 15.1 3.5 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) adh_short_C2 PF13561.6 KPI39234.1 - 2.4e-39 135.3 0.5 2.9e-36 125.2 0.2 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI39234.1 - 3.6e-34 117.9 2.7 1.5e-26 93.1 0.3 2.1 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 KPI39234.1 - 1.3e-05 24.8 1.6 0.0019 17.7 1.6 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPI39234.1 - 0.00023 20.4 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KPI39234.1 - 0.00035 20.5 4.0 0.0024 17.8 0.2 2.2 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KPI39234.1 - 0.016 14.6 0.1 0.36 10.2 0.0 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPI39235.1 - 5.9e-27 94.4 0.0 1.9e-24 86.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39235.1 - 2.8e-17 63.1 0.4 6.6e-08 32.4 0.0 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KPI39235.1 - 0.085 12.6 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 KPI39235.1 - 0.14 12.0 1.1 1.9 8.4 0.5 2.4 2 1 0 2 2 2 0 KR domain BcrAD_BadFG PF01869.20 KPI39237.1 - 8.9e-17 61.5 2.1 2.9e-16 59.8 0.2 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KPI39237.1 - 4e-07 30.1 0.2 4e-07 30.1 0.2 2.6 2 1 0 2 2 2 1 SIS domain SIS PF01380.22 KPI39237.1 - 5.6e-05 23.0 1.2 0.00015 21.6 0.1 2.2 2 0 0 2 2 2 1 SIS domain ParA PF10609.9 KPI39238.1 - 1.9e-77 260.1 0.0 3.1e-77 259.3 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KPI39238.1 - 4.3e-10 39.7 0.0 2.4e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KPI39238.1 - 5.7e-08 32.9 0.1 1.6e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KPI39238.1 - 0.0012 18.2 0.2 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 KPI39238.1 - 0.0029 17.2 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KPI39238.1 - 0.003 16.8 0.4 0.037 13.2 0.1 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase zf_UBZ PF18439.1 KPI39238.1 - 0.2 11.3 0.3 0.35 10.5 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger AAA_26 PF13500.6 KPI39238.1 - 0.25 11.2 0.4 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Nucleoside_tran PF01733.18 KPI39240.1 - 1.4e-29 103.5 8.1 1.6e-29 103.3 8.1 1.0 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KPI39240.1 - 0.0015 17.5 7.3 0.0015 17.5 7.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DWNN PF08783.11 KPI39241.1 - 3.6e-27 94.5 0.5 1.8e-26 92.2 0.1 2.2 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KPI39241.1 - 4.8e-08 32.7 8.0 8.8e-08 31.8 8.0 1.4 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 KPI39241.1 - 2.4e-07 30.8 0.0 8.8e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.23 KPI39241.1 - 0.0004 20.3 1.6 0.00082 19.3 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_UBOX PF13445.6 KPI39241.1 - 0.0041 17.1 6.6 0.0082 16.1 6.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI39241.1 - 0.0058 16.5 8.0 0.0058 16.5 8.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPI39241.1 - 0.017 15.3 8.1 0.04 14.1 8.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCHC_3 PF13917.6 KPI39241.1 - 0.022 14.7 0.6 0.048 13.6 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KPI39241.1 - 0.078 12.7 0.9 0.24 11.1 0.9 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-Nse PF11789.8 KPI39241.1 - 0.087 12.7 2.7 0.21 11.5 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KPI39241.1 - 0.13 12.1 5.0 0.29 10.9 5.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KPI39241.1 - 0.13 12.1 7.0 0.32 10.9 7.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI39241.1 - 1.2 9.0 10.0 1.4 8.9 4.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI39241.1 - 8.4 6.8 13.3 0.14 12.5 6.2 1.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KPI39241.1 - 9.4 6.3 12.0 1.2 9.1 6.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Ank_2 PF12796.7 KPI39242.1 - 3.8e-26 91.5 21.9 2.1e-05 25.0 0.0 11.7 7 5 9 17 17 17 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI39242.1 - 1.9e-20 73.0 18.2 0.044 14.4 0.0 14.0 12 2 1 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI39242.1 - 3.5e-11 42.3 10.9 6 7.8 0.0 14.9 18 0 0 18 18 18 1 Ankyrin repeat Ank_5 PF13857.6 KPI39242.1 - 2.2e-08 34.2 5.8 0.21 12.0 0.0 9.2 10 1 1 11 11 11 2 Ankyrin repeats (many copies) Ank PF00023.30 KPI39242.1 - 1.1e-07 32.0 20.4 0.7 10.4 0.0 11.9 13 1 0 13 13 13 2 Ankyrin repeat Coagulin PF02035.15 KPI39242.1 - 0.22 11.4 0.5 0.46 10.3 0.5 1.5 1 0 0 1 1 1 0 Coagulin HTH_Tnp_IS630 PF01710.16 KPI39243.1 - 0.086 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Transposase MFS_1 PF07690.16 KPI39245.1 - 3.5e-10 39.4 40.6 1e-09 37.8 39.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPI39245.1 - 3e-07 30.3 4.7 3e-07 30.3 4.7 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 LapA_dom PF06305.11 KPI39245.1 - 0.22 11.3 0.1 0.22 11.3 0.1 3.9 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 KPI39246.1 - 2.5e-29 102.3 32.7 2.5e-29 102.3 32.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 KPI39247.1 - 1.8e-94 317.0 34.6 2.1e-94 316.8 34.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CoA_transf_3 PF02515.17 KPI39248.1 - 2.7e-37 128.8 0.0 8.8e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III Pox_Ag35 PF03286.14 KPI39249.1 - 0.2 11.5 12.8 0.21 11.3 12.6 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Hep_59 PF07052.11 KPI39250.1 - 4.1e-08 33.9 0.2 2.4e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF3591 PF12157.8 KPI39251.1 - 3.1e-148 494.1 9.7 2.5e-146 487.8 9.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KPI39251.1 - 0.0043 17.1 0.7 0.0097 16.0 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zinc_ribbon_2 PF13240.6 KPI39251.1 - 0.069 12.9 4.1 2.9 7.7 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KPI39251.1 - 0.18 11.2 2.7 1 8.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_6 PF15288.6 KPI39251.1 - 3.5 7.5 6.1 0.31 10.9 0.7 2.1 2 0 0 2 2 2 0 Zinc knuckle TPT PF03151.16 KPI39252.1 - 6e-20 71.8 19.2 7.5e-20 71.4 19.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPI39252.1 - 9.1e-08 32.4 34.4 0.00012 22.2 9.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family Herpes_LMP1 PF05297.11 KPI39252.1 - 10 5.2 6.2 17 4.5 6.2 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Aldo_ket_red PF00248.21 KPI39253.1 - 8.2e-44 149.9 0.0 2e-43 148.7 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family PTR2 PF00854.21 KPI39255.1 - 1.3e-80 271.2 10.8 1.6e-80 270.9 10.8 1.1 1 0 0 1 1 1 1 POT family Sugar_tr PF00083.24 KPI39255.1 - 0.0021 17.0 0.6 0.0021 17.0 0.6 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter LETM1 PF07766.13 KPI39255.1 - 0.2 11.0 0.1 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 LETM1-like protein DUF3042 PF11240.8 KPI39255.1 - 1.5 8.9 3.1 1.2e+02 2.8 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) PEPCK_ATP PF01293.20 KPI39256.1 - 2e-188 626.8 0.1 1.7e-185 617.1 0.1 2.1 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KPI39256.1 - 0.18 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Arrestin_C PF02752.22 KPI39257.1 - 8.1e-15 55.5 0.0 2.2e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KPI39257.1 - 2.3e-10 40.7 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KPI39257.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Rad4 PF03835.15 KPI39258.1 - 1.4e-34 118.8 0.0 4.4e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KPI39258.1 - 4.3e-24 84.7 0.1 9.9e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KPI39258.1 - 5.1e-20 71.0 0.1 1e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KPI39258.1 - 6.7e-15 55.8 0.9 6.7e-15 55.8 0.9 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KPI39258.1 - 0.0032 17.9 0.0 0.0077 16.7 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily PBP1_TM PF14812.6 KPI39258.1 - 4.2 7.8 15.6 5.7 7.4 1.4 4.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7tm_2 PF00002.24 KPI39259.1 - 0.02 14.2 1.1 0.041 13.2 1.1 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) 6PGD PF00393.19 KPI39261.1 - 7.2e-127 422.7 0.0 9.2e-127 422.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KPI39261.1 - 5.4e-50 169.6 0.0 8.3e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI39261.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MCM PF00493.23 KPI39263.1 - 2.1e-101 337.7 0.0 3.3e-101 337.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPI39263.1 - 6.1e-32 110.1 0.4 1.2e-31 109.1 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KPI39263.1 - 2e-28 98.6 1.7 2e-28 98.6 1.7 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KPI39263.1 - 4.9e-16 59.2 0.1 4.1e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPI39263.1 - 6.4e-06 25.7 0.0 0.00018 21.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPI39263.1 - 1e-05 25.5 0.0 4.1e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KPI39263.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AMP-binding PF00501.28 KPI39264.1 - 3.2e-100 335.7 0.0 3.7e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI39264.1 - 8.1e-16 58.8 0.4 1.9e-15 57.6 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1368 PF07112.11 KPI39264.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) MBOAT PF03062.19 KPI39265.1 - 3.7e-18 66.0 15.7 4.9e-18 65.6 15.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KPI39265.1 - 8e-05 22.8 5.2 0.00032 20.9 5.2 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GDE_N_bis PF14742.6 KPI39266.1 - 0.057 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes NYD-SP28_assoc PF14775.6 KPI39267.1 - 0.059 13.5 1.3 0.3 11.2 1.3 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain AA_permease PF00324.21 KPI39268.1 - 2.4e-85 286.9 38.2 3.4e-84 283.1 38.2 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI39268.1 - 3e-15 56.0 41.4 2.7e-14 52.9 41.4 2.0 1 1 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KPI39270.1 - 7.8e-19 67.9 0.0 1.3e-18 67.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39270.1 - 4.6e-09 36.2 0.0 1.9e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KPI39270.1 - 8.1e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KPI39270.1 - 0.0013 18.6 0.4 0.0026 17.7 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI39270.1 - 0.0026 17.2 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI39270.1 - 0.012 15.5 0.7 0.025 14.5 0.7 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF1161 PF06649.12 KPI39270.1 - 0.017 15.3 0.2 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) RT_RNaseH_2 PF17919.1 KPI39270.1 - 0.041 13.9 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase AA_permease PF00324.21 KPI39271.1 - 8.9e-95 318.0 50.0 2.5e-93 313.3 50.0 2.2 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI39271.1 - 3.9e-15 55.6 49.5 5.5e-15 55.1 49.5 1.2 1 0 0 1 1 1 1 Amino acid permease Lectin_leg-like PF03388.13 KPI39273.1 - 2.7e-62 210.1 0.0 3.4e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KPI39273.1 - 5.8e-07 29.7 0.2 7.8e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KPI39273.1 - 0.00051 19.6 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain UQ_con PF00179.26 KPI39274.1 - 8.2e-19 67.6 0.1 9e-19 67.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAD_binding_1 PF00667.20 KPI39275.1 - 2.4e-37 128.7 0.0 1e-21 77.6 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain DLH PF01738.18 KPI39276.1 - 2.2e-14 53.6 0.0 6.9e-14 51.9 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 KPI39277.1 - 2.3e-12 46.5 0.1 4.1e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI39277.1 - 8e-10 38.7 9.9 1.5e-09 37.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 KPI39278.1 - 3e-22 78.5 0.2 4.1e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.28 KPI39279.1 - 3.9e-26 91.2 0.0 1.6e-25 89.3 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KPI39279.1 - 1.2e-24 86.8 0.9 1.2e-24 86.8 0.9 2.4 2 2 0 2 2 2 1 Nucleoplasmin-like domain Zip PF02535.22 KPI39280.1 - 3e-14 53.0 6.2 3.5e-06 26.5 0.9 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF1771 PF08590.10 KPI39281.1 - 5.5e-07 29.9 8.3 1.6e-06 28.4 8.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 KPI39281.1 - 2.2e-05 24.0 0.4 0.046 13.4 0.0 3.2 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 KPI39281.1 - 0.00035 20.9 0.0 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 Smr domain Nucleoside_tran PF01733.18 KPI39282.1 - 4.9e-15 55.7 1.3 8.1e-15 55.0 1.0 1.5 1 1 0 1 1 1 1 Nucleoside transporter KAR9 PF08580.10 KPI39283.1 - 1.1e-147 493.5 15.7 9.3e-147 490.5 15.7 1.9 1 1 0 1 1 1 1 Yeast cortical protein KAR9 Mod_r PF07200.13 KPI39283.1 - 0.011 15.9 1.2 0.011 15.9 1.2 3.5 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein SIMPL PF04402.14 KPI39283.1 - 1.1 9.7 6.6 0.4 11.1 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF541) YabA PF06156.13 KPI39283.1 - 2.4 8.8 8.2 14 6.4 0.2 3.5 3 0 0 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 KPI39283.1 - 2.7 8.2 11.2 0.74 10.0 1.3 4.5 5 0 0 5 5 5 0 bZIP transcription factor Val_tRNA-synt_C PF10458.9 KPI39283.1 - 2.9 8.2 8.4 0.34 11.2 1.6 2.8 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DivIVA PF05103.13 KPI39283.1 - 6.1 6.9 8.7 1.3 9.1 0.8 2.8 3 0 0 3 3 3 0 DivIVA protein DUF4795 PF16043.5 KPI39283.1 - 7.4 6.1 16.7 79 2.8 3.0 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4332 PF14229.6 KPI39283.1 - 9.2 6.5 8.2 25 5.1 0.6 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4332) NAD_binding_10 PF13460.6 KPI39284.1 - 1.6e-07 31.4 0.0 2.4e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI39284.1 - 2.9e-06 26.9 0.0 7e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KPI39284.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 HIM1 KR PF08659.10 KPI39284.1 - 0.0023 17.9 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KPI39284.1 - 0.01 15.0 0.4 0.56 9.3 0.2 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 KPI39284.1 - 0.011 15.2 0.2 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family NAD_binding_4 PF07993.12 KPI39284.1 - 0.019 14.1 0.0 4.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein DUF917 PF06032.12 KPI39285.1 - 6.1e-127 423.3 0.1 4.3e-125 417.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KPI39285.1 - 1.7e-25 89.7 0.0 4e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPI39285.1 - 7.4e-18 64.8 0.8 1.7e-05 24.2 0.0 4.3 2 1 2 4 4 4 4 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KPI39285.1 - 0.002 17.7 0.1 0.072 12.6 0.0 2.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DAHP_snth_FXD PF18152.1 KPI39285.1 - 0.059 13.2 0.1 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Glyco_hydro_cc PF11790.8 KPI39286.1 - 4.2e-49 167.3 0.1 5.4e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ILVD_EDD PF00920.21 KPI39288.1 - 7.1e-158 526.4 0.1 8.1e-158 526.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Amidohydro_1 PF01979.20 KPI39289.1 - 7.3e-27 94.6 0.0 1.2e-26 93.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI39289.1 - 2.2e-13 50.5 0.1 2.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF3605 PF12239.8 KPI39291.1 - 1.9e-59 200.4 0.0 2.3e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Actin PF00022.19 KPI39292.1 - 5.6e-133 443.5 0.0 6.4e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KPI39292.1 - 8.9e-05 21.4 0.1 0.2 10.4 0.0 3.0 2 1 0 3 3 3 3 MreB/Mbl protein SGL PF08450.12 KPI39293.1 - 1.9e-13 50.6 0.0 3.8e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Ank_2 PF12796.7 KPI39294.1 - 1.1e-35 122.0 0.0 4.1e-11 43.3 0.0 8.4 8 1 0 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI39294.1 - 1.6e-32 111.4 0.5 4.9e-05 23.8 0.0 10.7 9 2 3 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI39294.1 - 1.4e-28 95.8 0.7 0.0004 20.6 0.0 12.4 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 KPI39294.1 - 6.5e-20 70.6 2.3 0.0016 18.8 0.1 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KPI39294.1 - 4.5e-18 65.1 1.8 0.0015 18.8 0.1 7.8 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Sugar_tr PF00083.24 KPI39295.1 - 1.3e-91 307.8 25.2 1.6e-91 307.5 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39295.1 - 3.5e-18 65.7 44.7 3.8e-14 52.4 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HeLo PF14479.6 KPI39296.1 - 3.1e-05 23.9 0.6 0.00063 19.6 0.5 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation tRNA-synt_1d PF00750.19 KPI39297.1 - 1.4e-38 132.8 0.0 2.3e-26 92.6 0.1 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (R) ATG13 PF10033.9 KPI39298.1 - 5.6e-59 199.7 0.0 1e-58 198.9 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 ICMT PF04140.14 KPI39299.1 - 3.8e-29 101.0 1.1 6.6e-29 100.2 1.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KPI39299.1 - 1.7e-14 54.1 2.2 3.5e-14 53.1 2.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 KPI39299.1 - 0.0052 16.3 0.1 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 KPI39299.1 - 0.021 14.3 0.2 0.031 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) adh_short PF00106.25 KPI39301.1 - 1.6e-12 47.3 0.0 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39301.1 - 1.9e-10 40.7 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ins_P5_2-kin PF06090.12 KPI39302.1 - 3.7e-33 115.4 0.3 6.7e-30 104.7 0.0 2.1 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase Sedlin_N PF04628.13 KPI39303.1 - 7.2e-22 77.9 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Med20 PF08612.11 KPI39304.1 - 1.3e-11 44.4 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Atx10homo_assoc PF09759.9 KPI39305.1 - 1.4e-26 92.4 0.6 5.2e-26 90.5 0.1 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Abhydrolase_3 PF07859.13 KPI39306.1 - 4.7e-14 52.8 0.0 8.3e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI39306.1 - 2.1e-11 43.7 0.0 9.3e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KPI39306.1 - 4.6e-07 29.1 0.1 9.6e-07 28.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KPI39306.1 - 0.0006 19.5 0.2 0.032 13.9 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPI39306.1 - 0.0017 18.0 0.0 0.019 14.6 0.0 2.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KPI39306.1 - 0.0018 18.9 0.2 0.0025 18.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KPI39306.1 - 0.0038 17.0 0.0 0.65 9.8 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 KPI39306.1 - 0.009 14.7 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KPI39306.1 - 0.017 14.7 0.2 0.82 9.3 0.1 2.2 2 0 0 2 2 2 0 Putative esterase Esterase_phd PF10503.9 KPI39306.1 - 0.041 13.4 0.2 16 4.9 0.1 2.8 3 0 0 3 3 3 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KPI39306.1 - 0.049 12.9 0.1 9.2 5.4 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KPI39306.1 - 0.087 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Hat1_N PF10394.9 KPI39307.1 - 3.8e-45 154.0 0.0 8.1e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 KPI39307.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI39307.1 - 0.04 14.1 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family WD40 PF00400.32 KPI39309.1 - 8.7e-29 99.2 9.7 4.1e-06 27.4 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39309.1 - 2.2e-10 40.7 0.1 0.09 13.1 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain zf-Tim10_DDP PF02953.15 KPI39311.1 - 8.1e-20 70.2 0.3 1.3e-19 69.6 0.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tmemb_170 PF10190.9 KPI39312.1 - 2.3e-22 79.4 11.8 2.1e-17 63.4 1.7 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 DUF2530 PF10745.9 KPI39312.1 - 3.4 8.0 7.7 0.65 10.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) RNA_pol_Rpb2_6 PF00562.28 KPI39313.1 - 1.9e-95 320.2 0.1 1.9e-66 224.7 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KPI39313.1 - 2.5e-34 118.6 0.0 4.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KPI39313.1 - 2.6e-28 98.0 0.0 6.6e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KPI39313.1 - 9.9e-23 79.9 0.0 2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KPI39313.1 - 2e-21 76.5 0.0 3.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KPI39313.1 - 4.3e-16 59.1 0.1 2.6e-15 56.6 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Cpn60_TCP1 PF00118.24 KPI39314.1 - 3.7e-157 523.9 4.4 4.2e-157 523.7 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 KPI39314.1 - 0.038 14.1 0.4 1.7 8.7 0.1 3.0 3 0 0 3 3 3 0 Resolvase, N terminal domain Acyltransferase PF01553.21 KPI39316.1 - 1.1e-12 47.7 0.0 2.9e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase XRN1_DBM PF18245.1 KPI39316.1 - 0.11 12.5 2.6 0.32 11.0 0.2 2.4 2 0 0 2 2 2 0 5-3 exonuclease XRN1 DCP1-binding motif CTK3 PF12243.8 KPI39317.1 - 1.9e-39 134.4 0.0 3.2e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KPI39317.1 - 4.4e-16 58.8 9.4 4.4e-16 58.8 9.4 2.1 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Nrap_D5 PF17406.2 KPI39317.1 - 0.099 12.4 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Phlebovirus_NSM PF07246.11 KPI39317.1 - 0.29 10.5 0.1 0.29 10.5 0.1 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Methyltransf_23 PF13489.6 KPI39318.1 - 3.2e-25 88.9 0.0 6.3e-25 87.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI39318.1 - 3.4e-14 53.3 0.0 9.4e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39318.1 - 4.4e-11 42.8 0.0 2.7e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39318.1 - 5.4e-11 43.0 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39318.1 - 3e-10 40.7 0.0 1.2e-09 38.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI39318.1 - 2.9e-05 23.5 0.0 0.00014 21.3 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPI39318.1 - 0.0021 18.2 0.0 0.0041 17.2 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF938 PF06080.12 KPI39318.1 - 0.0055 16.5 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KPI39318.1 - 0.0098 15.4 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KPI39318.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KPI39318.1 - 0.012 15.0 0.0 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain CMAS PF02353.20 KPI39318.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase dNK PF01712.19 KPI39318.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Methyltransf_16 PF10294.9 KPI39318.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase BTB PF00651.31 KPI39319.1 - 2.3e-07 31.0 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1761 PF08570.10 KPI39320.1 - 0.02 15.1 3.1 0.021 15.1 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) FtsX PF02687.21 KPI39320.1 - 0.28 11.7 8.7 0.26 11.8 5.4 2.0 2 0 0 2 2 2 0 FtsX-like permease family DUF2070 PF09843.9 KPI39320.1 - 0.54 8.5 5.9 0.72 8.1 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Herpes_LMP1 PF05297.11 KPI39320.1 - 1.2 8.2 5.4 1.6 7.8 5.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Oxidored_FMN PF00724.20 KPI39321.1 - 1.5e-57 195.4 0.0 2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.32 KPI39324.1 - 3e-42 141.8 10.8 1.3e-06 29.1 0.0 8.8 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39324.1 - 2.4e-15 56.6 0.0 0.0032 17.7 0.0 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI39324.1 - 8e-06 25.0 0.1 0.0043 16.1 0.0 3.8 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPI39324.1 - 0.00052 18.8 2.3 0.32 9.6 0.1 3.7 2 2 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KPI39324.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Frtz PF11768.8 KPI39324.1 - 0.13 10.6 0.0 0.22 9.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Isochorismatase PF00857.20 KPI39325.1 - 8.1e-22 78.2 0.0 3.8e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family Fe_dep_repress PF01325.19 KPI39328.1 - 0.0054 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Acyltransferase PF01553.21 KPI39329.1 - 2.3e-30 105.0 0.0 3.3e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF1574 PF07611.11 KPI39329.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) DEAD PF00270.29 KPI39330.1 - 1.3e-41 142.2 0.9 2.1e-41 141.6 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI39330.1 - 4.7e-30 104.2 0.1 2.6e-29 101.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI39330.1 - 5.5e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TRAUB PF08164.12 KPI39331.1 - 3.4e-25 88.4 0.0 2.7e-24 85.5 0.0 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KPI39331.1 - 6.1e-20 72.3 3.6 6.1e-20 72.3 3.6 2.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Glyco_hydro_61 PF03443.14 KPI39332.1 - 2.7e-62 210.4 0.0 3.7e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KPI39332.1 - 1.3e-12 47.4 9.1 3.1e-12 46.2 9.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain RED_N PF07808.13 KPI39333.1 - 3.2e-08 33.4 5.6 3.2e-08 33.4 5.6 2.4 2 1 0 2 2 2 1 RED-like protein N-terminal region Methyltransf_15 PF09445.10 KPI39334.1 - 9.8e-49 165.1 0.0 1.4e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KPI39334.1 - 7.1e-07 29.2 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 KPI39334.1 - 7.2e-07 29.1 0.0 2.7e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KPI39334.1 - 2e-05 25.2 0.0 3.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39334.1 - 0.00021 21.1 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 KPI39334.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Cons_hypoth95 PF03602.15 KPI39334.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KPI39334.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPI39334.1 - 0.0047 16.5 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KPI39334.1 - 0.0048 17.5 0.0 0.0094 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KPI39334.1 - 0.0058 16.6 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KPI39334.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa TPMT PF05724.11 KPI39334.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_5 PF01795.19 KPI39334.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family p450 PF00067.22 KPI39335.1 - 3.2e-70 237.2 0.0 3.9e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHRD PF07452.12 KPI39337.1 - 0.0067 17.4 0.0 0.012 16.5 0.0 1.4 1 0 0 1 1 1 1 CHRD domain F-box-like PF12937.7 KPI39338.1 - 0.0046 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI39338.1 - 0.049 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain zf-BED PF02892.15 KPI39339.1 - 0.0066 16.5 0.3 0.0096 15.9 0.3 1.4 1 0 0 1 1 1 1 BED zinc finger CsbD PF05532.12 KPI39340.1 - 0.0024 17.7 6.2 0.0054 16.6 6.2 1.6 1 0 0 1 1 1 1 CsbD-like DUF977 PF06163.11 KPI39340.1 - 0.017 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Dicty_REP PF05086.12 KPI39340.1 - 1.8 6.4 8.0 1.8 6.4 8.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_L18_c PF14204.6 KPI39340.1 - 4.8 8.2 9.4 8.5 7.4 1.1 2.0 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region SnoaL PF07366.12 KPI39341.1 - 0.0031 17.3 0.0 0.0071 16.1 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPI39341.1 - 0.004 17.8 0.0 0.0068 17.0 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPI39341.1 - 0.037 14.4 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) TMEM171 PF15471.6 KPI39341.1 - 0.12 11.4 0.7 0.16 10.9 0.7 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 PMI_typeI PF01238.21 KPI39342.1 - 1.3e-72 245.1 0.2 1.2e-71 241.9 0.2 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KPI39342.1 - 0.012 15.5 0.0 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.11 KPI39342.1 - 0.17 11.6 0.1 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Beta-lactamase PF00144.24 KPI39343.1 - 1e-23 84.1 0.6 1.6e-23 83.5 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase S6PP_C PF08472.10 KPI39343.1 - 0.17 11.8 0.2 0.42 10.5 0.2 1.6 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal F-actin_cap_A PF01267.17 KPI39344.1 - 3e-82 276.0 0.0 3.4e-82 275.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cornifin PF02389.15 KPI39345.1 - 0.0025 18.0 4.4 0.0031 17.7 4.4 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family TauD PF02668.16 KPI39346.1 - 7.4e-35 121.0 0.3 1e-34 120.6 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KPI39346.1 - 0.032 13.3 0.0 0.069 12.3 0.0 1.4 2 0 0 2 2 2 0 CsiD AAA PF00004.29 KPI39347.1 - 2.3e-17 63.7 0.0 4.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI39347.1 - 0.00074 19.8 0.3 0.02 15.2 0.0 2.9 1 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KPI39347.1 - 0.001 19.5 0.0 0.0032 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KPI39347.1 - 0.004 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPI39347.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Vps36_ESCRT-II PF11605.8 KPI39347.1 - 0.029 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DnaB_C PF03796.15 KPI39347.1 - 0.05 12.9 0.3 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zot PF05707.12 KPI39347.1 - 0.072 12.7 0.0 0.89 9.2 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 KPI39347.1 - 0.081 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KPI39347.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KPI39347.1 - 0.2 11.0 0.3 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 KaiC AOX PF01786.17 KPI39348.1 - 9.7e-82 273.7 1.0 2.8e-80 268.9 1.0 2.0 1 1 0 1 1 1 1 Alternative oxidase Glyoxalase PF00903.25 KPI39349.1 - 2e-11 44.2 0.0 4.8e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPI39349.1 - 2.8e-06 27.6 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KPI39349.1 - 5.3e-05 23.4 0.0 0.00088 19.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KPI39349.1 - 0.00025 20.9 0.0 0.0004 20.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KPI39349.1 - 0.0083 16.9 0.0 0.017 15.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Sugar_tr PF00083.24 KPI39350.1 - 6.7e-81 272.4 14.9 8.3e-81 272.1 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39350.1 - 1.6e-10 40.4 29.7 1.6e-10 40.4 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 KPI39351.1 - 4.9e-40 136.2 2.1 1.4e-38 131.5 0.7 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPI39351.1 - 2.2e-37 127.9 7.2 1.1e-34 119.1 0.3 3.5 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KPI39351.1 - 1.9e-17 63.8 0.2 5.7e-15 55.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Glyco_hydro_47 PF01532.20 KPI39352.1 - 1e-174 581.7 0.0 1.2e-174 581.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_9 PF00759.19 KPI39352.1 - 0.049 13.0 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Gpi16 PF04113.14 KPI39353.1 - 4.8e-227 754.9 0.0 6.2e-227 754.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component BUD22 PF09073.10 KPI39354.1 - 6.5e-82 276.2 17.8 7.6e-82 276.0 17.8 1.0 1 0 0 1 1 1 1 BUD22 Arrestin_N PF00339.29 KPI39356.1 - 3.4e-06 27.2 0.0 8.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_3_C PF01915.22 KPI39357.1 - 3e-51 174.3 0.0 5.8e-51 173.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI39357.1 - 9.8e-48 163.1 0.0 1.7e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI39357.1 - 5e-19 68.2 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPI39357.1 - 1.9e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 PA14 domain REV1_C PF16727.5 KPI39358.1 - 2.8e-25 88.6 0.3 4.4e-25 87.9 0.3 1.3 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 KPI39358.1 - 2.7e-18 64.7 8.9 7.9e-07 28.3 0.4 3.5 3 0 0 3 3 3 3 Ubiquitin binding region YdaT_toxin PF06254.11 KPI39358.1 - 0.045 14.3 0.3 14 6.3 0.0 3.0 3 0 0 3 3 3 0 Putative bacterial toxin ydaT Rtt106_N PF18215.1 KPI39358.1 - 0.11 12.3 0.2 3.2 7.6 0.0 2.8 3 1 0 3 3 3 0 Histone chaperone Rtt106 N-terminal domain MgtE_N PF03448.17 KPI39358.1 - 0.14 12.8 1.5 21 5.8 0.0 3.0 3 0 0 3 3 3 0 MgtE intracellular N domain DUF2281 PF10047.9 KPI39358.1 - 0.14 12.8 0.8 14 6.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) TauD PF02668.16 KPI39359.1 - 1.1e-53 182.8 0.3 1.2e-53 182.6 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SRAP PF02586.14 KPI39361.1 - 5.4e-81 271.3 0.0 7.4e-81 270.9 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) DIOX_N PF14226.6 KPI39362.1 - 2.5e-19 70.1 0.0 5.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI39362.1 - 1.4e-13 51.1 0.0 2.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KPI39363.1 - 3.3e-15 56.2 13.0 0.00013 22.7 0.2 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39363.1 - 7.9e-10 38.9 0.0 0.0002 21.6 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KPI39363.1 - 7.6e-06 25.7 0.1 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KPI39363.1 - 0.0021 16.7 0.0 0.0059 15.2 0.0 1.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KPI39363.1 - 0.0037 17.2 0.1 0.0091 15.9 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPI39363.1 - 0.032 13.2 0.0 0.27 10.2 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KPI39363.1 - 0.083 12.6 0.5 7 6.4 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF2268 PF10026.9 KPI39364.1 - 0.17 11.5 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) FSA_C PF10479.9 KPI39364.1 - 0.82 7.7 4.2 1.2 7.2 4.2 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RS4NT PF08071.12 KPI39364.1 - 0.9 9.7 3.5 21 5.3 0.2 2.6 2 0 0 2 2 2 0 RS4NT (NUC023) domain GRASP55_65 PF04495.14 KPI39365.1 - 1.3e-39 135.7 0.0 4e-38 130.8 0.0 2.1 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain RCC1 PF00415.18 KPI39366.1 - 5e-20 71.9 0.3 3.3e-05 24.4 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KPI39366.1 - 2.2e-17 63.3 0.1 2.9e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KPI39366.1 - 3.5e-09 36.2 0.1 1.3e-07 31.2 0.3 3.3 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KPI39366.1 - 8.2e-09 35.8 0.1 5.4e-05 23.7 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI39366.1 - 1.4e-06 28.8 0.3 5e-06 27.0 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPI39366.1 - 0.00016 21.8 0.2 1.9 9.3 0.0 3.5 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 KPI39366.1 - 0.0034 17.8 0.1 1.7 9.2 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KPI39366.1 - 0.0075 16.6 0.7 12 6.4 0.0 4.1 3 1 0 3 3 3 1 Ankyrin repeats (many copies) RNA_pol_I_A49 PF06870.12 KPI39366.1 - 0.028 13.3 1.4 0.051 12.4 1.4 1.3 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor PKI PF02827.16 KPI39366.1 - 0.74 10.1 3.4 2.4 8.4 3.4 1.8 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor FHIPEP PF00771.20 KPI39366.1 - 3 6.2 4.7 0.28 9.6 0.1 1.5 2 0 0 2 2 2 0 FHIPEP family RrnaAD PF00398.20 KPI39367.1 - 3.6e-60 203.3 0.0 4.9e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KPI39367.1 - 1.4e-06 28.9 0.0 3.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39367.1 - 2.8e-05 24.7 0.0 6.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPI39367.1 - 0.00058 19.7 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KPI39367.1 - 0.0034 17.2 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPI39367.1 - 0.01 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KPI39367.1 - 0.024 15.4 0.0 0.065 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KPI39367.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KPI39367.1 - 0.033 13.7 0.2 0.078 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase AAA_lid_4 PF17864.1 KPI39367.1 - 0.063 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain PrmA PF06325.13 KPI39367.1 - 0.063 12.7 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KPI39367.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 KPI39367.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein WSC PF01822.19 KPI39368.1 - 1.9e-19 69.6 8.4 1.9e-19 69.6 8.4 3.6 2 1 0 2 2 2 1 WSC domain NAD_binding_2 PF03446.15 KPI39369.1 - 3.5e-40 137.8 0.8 4.8e-40 137.3 0.8 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI39369.1 - 4.9e-28 97.8 0.0 9.2e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KPI39369.1 - 0.0083 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DUF884 PF05959.11 KPI39369.1 - 0.14 11.8 0.2 0.38 10.4 0.1 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Indigoidine_A PF04227.12 KPI39370.1 - 1.6e-117 392.0 0.7 2.6e-117 391.3 0.7 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KPI39370.1 - 7.8e-22 77.9 0.4 1.9e-12 47.1 0.0 3.3 4 0 0 4 4 4 2 pfkB family carbohydrate kinase L31 PF09784.9 KPI39371.1 - 2.9e-45 152.9 1.2 3.2e-45 152.7 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF2161 PF09929.9 KPI39371.1 - 0.11 12.6 0.1 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) UCH PF00443.29 KPI39372.1 - 2e-39 135.7 0.0 3.1e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KPI39372.1 - 2.9e-25 87.8 0.1 5.6e-25 86.9 0.1 1.5 1 0 0 1 1 1 1 Variant UBP zinc finger UBA PF00627.31 KPI39372.1 - 9.9e-16 57.3 0.1 1.1e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KPI39372.1 - 3.6e-13 49.8 0.1 1.6e-11 44.4 0.1 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KPI39372.1 - 2.7e-06 27.6 0.8 9.6e-06 25.8 0.8 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_4 PF14555.6 KPI39372.1 - 0.00023 20.9 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.16 KPI39372.1 - 0.054 13.2 0.0 15 5.4 0.0 2.6 2 0 0 2 2 2 0 CUE domain PAP1 PF08601.10 KPI39373.1 - 2.9e-92 310.3 29.5 2.9e-92 310.3 29.5 2.1 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KPI39373.1 - 1.6e-09 37.7 8.5 4.3e-09 36.3 8.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 KPI39373.1 - 0.009 15.8 12.0 0.018 14.9 11.9 1.5 1 1 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_2 PF07716.15 KPI39373.1 - 0.013 15.5 12.0 0.03 14.4 10.4 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF16 PF01519.16 KPI39373.1 - 0.022 15.3 1.0 0.022 15.3 1.0 2.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 SlyX PF04102.12 KPI39373.1 - 0.032 14.9 0.4 0.11 13.2 0.4 1.9 1 0 0 1 1 1 0 SlyX Cnn_1N PF07989.11 KPI39373.1 - 0.048 13.8 1.6 0.15 12.2 1.6 1.9 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 IL11 PF07400.11 KPI39373.1 - 0.071 12.8 2.5 0.099 12.3 0.6 2.1 1 1 0 2 2 2 0 Interleukin 11 LMBR1 PF04791.16 KPI39373.1 - 6.3 5.6 8.3 9 5.1 8.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SHE3 PF17078.5 KPI39373.1 - 6.8 6.3 13.6 0.069 12.9 4.6 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 PRP1_N PF06424.12 KPI39374.1 - 2.4e-49 167.5 9.4 2.4e-49 167.5 9.4 2.6 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KPI39374.1 - 3.1e-27 92.9 27.5 0.0023 18.6 0.0 13.9 4 4 11 15 15 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 KPI39374.1 - 1.4e-24 86.4 3.2 4.2e-07 30.4 0.1 9.4 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KPI39374.1 - 1.3e-14 53.0 1.8 0.079 13.1 0.0 8.8 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI39374.1 - 4.7e-11 42.3 0.0 8.8 7.0 0.0 9.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI39374.1 - 1.2e-09 38.6 9.1 0.0025 18.4 0.7 7.4 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI39374.1 - 2e-08 33.8 1.5 0.041 14.1 0.0 6.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPI39374.1 - 7e-07 28.8 0.1 0.073 12.9 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KPI39374.1 - 2.3e-05 24.0 0.0 7.5 6.3 0.0 5.8 7 0 0 7 7 7 2 TPR repeat TPR_15 PF13429.6 KPI39374.1 - 3e-05 23.4 26.3 0.051 12.8 2.9 6.7 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPI39374.1 - 0.00038 20.7 0.1 9.7 6.6 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPI39374.1 - 0.00064 19.8 6.0 1.3 9.2 0.0 6.0 6 1 1 7 7 7 1 Tetratricopeptide repeat DUF3808 PF10300.9 KPI39374.1 - 0.0042 15.9 0.4 3.7 6.2 0.0 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF3808) TPR_21 PF09976.9 KPI39374.1 - 0.0057 16.4 12.3 0.21 11.3 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KPI39374.1 - 0.59 10.9 12.4 13 6.7 0.0 7.9 10 0 0 10 10 9 0 Tetratricopeptide repeat AD PF09793.9 KPI39375.1 - 1.3e-15 57.2 0.0 2.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain SOSSC PF15925.5 KPI39375.1 - 0.47 11.8 3.5 1 10.7 0.0 2.4 2 1 0 2 2 2 0 SOSS complex subunit C ADSL_C PF10397.9 KPI39376.1 - 2.1e-16 60.2 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus COX15-CtaA PF02628.15 KPI39377.1 - 8.5e-113 376.7 11.3 1e-112 376.4 11.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Comm PF15957.5 KPI39378.1 - 0.17 12.2 0.4 0.57 10.5 0.4 1.9 1 0 0 1 1 1 0 Commissureless Corona_S2 PF01601.16 KPI39378.1 - 0.98 7.8 10.0 1.3 7.5 10.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PEP-utilisers_N PF05524.13 KPI39379.1 - 1.4 9.1 7.1 0.38 11.0 0.7 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal COX7a PF02238.15 KPI39380.1 - 9e-21 74.0 1.5 1.5e-20 73.4 1.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Sugar_tr PF00083.24 KPI39381.1 - 1.1e-62 212.4 29.0 1.3e-62 212.2 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39381.1 - 1.1e-16 60.8 74.7 5e-16 58.6 41.0 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Trimer_CC PF08954.11 KPI39382.1 - 0.085 12.4 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 Trimerisation motif LMWPc PF01451.21 KPI39382.1 - 0.11 12.9 0.2 27 5.1 0.0 2.9 3 0 0 3 3 3 0 Low molecular weight phosphotyrosine protein phosphatase SopD PF11047.8 KPI39382.1 - 0.17 11.0 0.6 0.41 9.8 0.1 1.7 2 0 0 2 2 2 0 Salmonella outer protein D RNase_P_pop3 PF08228.11 KPI39383.1 - 4.1e-06 26.9 0.0 9.9e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 RNase P subunit Pop3 Beta-lactamase PF00144.24 KPI39384.1 - 5.7e-43 147.4 0.3 1.6e-42 146.0 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase Velvet PF11754.8 KPI39385.1 - 4.7e-26 92.2 0.0 5.5e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Velvet factor SH3_9 PF14604.6 KPI39386.1 - 0.00048 19.9 0.1 0.00048 19.9 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KPI39386.1 - 0.0012 18.4 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KPI39386.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SNARE PF05739.19 KPI39387.1 - 7.9e-16 57.8 2.4 9.2e-16 57.6 0.7 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KPI39387.1 - 5.2e-05 23.0 9.5 0.00028 20.6 9.5 1.9 1 1 0 1 1 1 1 Syntaxin DNA_repr_REX1B PF14966.6 KPI39387.1 - 0.0028 18.3 0.2 0.019 15.6 0.0 2.4 2 0 0 2 2 2 1 DNA repair REX1-B SlyX PF04102.12 KPI39387.1 - 0.04 14.5 2.6 2.1 9.0 0.1 3.1 2 1 1 3 3 3 0 SlyX Syntaxin_2 PF14523.6 KPI39387.1 - 0.21 12.0 5.2 0.13 12.7 2.0 2.0 2 1 0 2 2 2 0 Syntaxin-like protein Cdh1_DBD_1 PF18196.1 KPI39387.1 - 0.61 10.4 6.4 2.8 8.3 0.6 3.0 2 1 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 MCPsignal PF00015.21 KPI39387.1 - 0.79 9.5 10.2 0.11 12.2 1.0 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain His_biosynth PF00977.21 KPI39388.1 - 3.8e-48 164.0 2.0 6.3e-47 159.9 2.0 2.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KPI39388.1 - 5.8e-22 78.4 0.0 9.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KPI39388.1 - 9.5e-09 35.4 0.0 8.4e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KPI39388.1 - 2e-07 30.8 0.0 6.3e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KPI39388.1 - 0.0026 17.6 0.2 0.011 15.6 0.0 2.1 3 0 0 3 3 3 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KPI39388.1 - 0.0073 16.1 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 KOW PF00467.29 KPI39388.1 - 0.1 12.6 0.4 0.25 11.4 0.4 1.7 1 0 0 1 1 1 0 KOW motif Dus PF01207.17 KPI39388.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Pkinase PF00069.25 KPI39389.1 - 6.1e-71 238.9 0.0 9.7e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39389.1 - 3.6e-46 157.6 0.0 6e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KPI39389.1 - 1.1e-17 64.1 0.1 3.4e-17 62.6 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KPI39389.1 - 1.3e-06 27.4 1.1 2.6e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KPI39389.1 - 1.4e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 KPI39389.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 KPI39389.1 - 0.025 13.5 0.1 0.058 12.3 0.1 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KPI39389.1 - 0.14 11.5 0.5 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pinin_SDK_memA PF04696.13 KPI39390.1 - 2.3e-20 73.0 15.8 4.1e-20 72.2 15.8 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region OST3_OST6 PF04756.13 KPI39391.1 - 1.7e-76 257.4 0.0 2e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KPI39391.1 - 0.0048 16.9 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HXXEE PF13787.6 KPI39391.1 - 0.036 14.8 0.3 0.067 14.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif Endonuclease_NS PF01223.23 KPI39393.1 - 3.1e-64 216.9 0.0 3.6e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease adh_short PF00106.25 KPI39394.1 - 2.6e-33 115.2 0.0 3.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39394.1 - 2.3e-22 79.7 0.0 2.8e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39394.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 KR domain MAS20 PF02064.15 KPI39395.1 - 1.4e-17 64.0 0.0 1.4e-17 64.0 0.0 2.6 4 0 0 4 4 4 1 MAS20 protein import receptor TPR_8 PF13181.6 KPI39395.1 - 5.1e-06 26.3 0.2 0.36 11.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KPI39395.1 - 0.00032 20.6 1.3 1.5 9.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPI39395.1 - 0.0042 17.4 1.3 2.9 8.3 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPI39395.1 - 0.018 15.6 4.9 10 7.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPI39395.1 - 0.058 13.4 0.6 21 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Inhibitor_I24 PF10465.9 KPI39395.1 - 0.13 12.2 0.2 0.55 10.2 0.1 2.2 2 1 0 2 2 2 0 PinA peptidase inhibitor TPR_10 PF13374.6 KPI39395.1 - 0.58 10.1 5.3 0.64 10.0 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NUDE_C PF04880.13 KPI39397.1 - 4.7e-40 137.9 8.5 4.7e-40 137.9 8.5 4.8 3 1 2 5 5 5 1 NUDE protein, C-terminal conserved region ALMT PF11744.8 KPI39397.1 - 2.3 6.9 10.9 3.8 6.2 10.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Tropomyosin_1 PF12718.7 KPI39397.1 - 3.8 7.7 40.6 11 6.1 27.3 4.0 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.8 KPI39397.1 - 4.3 4.7 26.4 7.6 3.9 26.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 KPI39397.1 - 4.3 7.7 32.9 1.6 9.1 14.3 2.9 2 1 1 3 3 3 0 Fez1 ADIP PF11559.8 KPI39397.1 - 5.9 7.0 36.0 0.19 11.8 13.3 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 KPI39397.1 - 7.2 5.3 22.6 1.1 8.0 15.7 2.3 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAA_hydrolase PF01557.18 KPI39398.1 - 1.2e-49 168.9 0.0 1.5e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family LSDAT_euk PF18139.1 KPI39398.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 SLOG in TRPM IMS PF00817.20 KPI39399.1 - 1.1e-41 142.3 0.0 1.9e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 KPI39399.1 - 5e-12 46.1 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 KPI39399.1 - 3.4e-11 43.9 0.0 8.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.26 KPI39399.1 - 2.4e-06 27.8 0.0 7.6e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KPI39399.1 - 4.3e-05 23.6 0.6 0.00025 21.2 0.1 2.6 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KPI39399.1 - 6.2e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KPI39399.1 - 0.00024 21.0 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain mCpol PF18182.1 KPI39399.1 - 0.00029 21.1 0.2 0.0032 17.8 0.0 2.3 2 0 0 2 2 2 1 minimal CRISPR polymerase domain DUF1805 PF08827.11 KPI39399.1 - 0.028 14.7 0.0 0.088 13.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Cdd1 PF11731.8 KPI39399.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus Aldo_ket_red PF00248.21 KPI39401.1 - 3.4e-33 115.1 0.0 5.4e-32 111.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family GPAT_N PF14829.6 KPI39401.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal SelR PF01641.18 KPI39402.1 - 1.3e-50 170.6 0.7 1.6e-50 170.2 0.7 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KPI39402.1 - 0.0015 18.3 0.2 0.49 10.2 0.0 2.3 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein GFA PF04828.14 KPI39402.1 - 0.014 15.8 0.9 1.1 9.6 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.12 KPI39402.1 - 0.034 13.7 1.5 0.82 9.2 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.14 KPI39402.1 - 0.077 13.2 1.3 0.16 12.2 0.5 2.0 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MCM_OB PF17207.3 KPI39402.1 - 0.083 12.7 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 MCM OB domain Tnp_zf-ribbon_2 PF13842.6 KPI39402.1 - 0.094 13.5 0.1 25 5.8 0.1 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.7 KPI39402.1 - 0.5 10.4 4.5 6.1 7.0 4.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.19 KPI39402.1 - 1.3 9.2 5.7 8.2 6.7 1.3 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e zf-Mss51 PF13824.6 KPI39402.1 - 2.1 8.5 4.8 8.5 6.6 1.2 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_cc PF11790.8 KPI39404.1 - 9.3e-46 156.3 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HET PF06985.11 KPI39406.1 - 1e-28 100.5 0.0 1.6e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.8 KPI39407.1 - 1.4e-25 89.5 16.0 5.4e-18 65.2 4.2 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) ECH_1 PF00378.20 KPI39408.1 - 5.8e-35 120.8 0.1 7e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI39408.1 - 2.9e-21 76.3 0.0 3.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribophorin_I PF04597.14 KPI39409.1 - 3.1e-138 461.7 0.2 3.5e-138 461.5 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I RCR PF12273.8 KPI39410.1 - 0.0017 19.0 13.9 0.0047 17.6 13.9 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CBP4 PF07960.11 KPI39410.1 - 0.042 13.7 0.2 0.064 13.1 0.2 1.2 1 0 0 1 1 1 0 CBP4 ADH_zinc_N PF00107.26 KPI39411.1 - 3.5e-22 78.8 0.6 5.5e-22 78.1 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI39411.1 - 3.6e-22 78.3 1.6 7e-22 77.4 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI39411.1 - 3.9e-07 31.2 0.0 6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_4 PF12146.8 KPI39413.1 - 1.5e-12 47.3 0.0 3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI39413.1 - 1.6e-12 47.6 0.0 9.3e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI39413.1 - 1.3e-11 45.5 0.2 1.7e-11 45.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KPI39413.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI39413.1 - 0.00092 18.7 0.0 0.62 9.5 0.0 3.0 2 1 1 3 3 3 1 Prolyl oligopeptidase family UPF0227 PF05728.12 KPI39413.1 - 0.00097 19.1 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 KPI39413.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KPI39413.1 - 0.051 13.2 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Eno-Rase_NADH_b PF12242.8 KPI39413.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ndr PF03096.14 KPI39413.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Palm_thioest PF02089.15 KPI39413.1 - 0.19 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AnmK PF03702.14 KPI39414.1 - 1.1e-73 248.5 0.0 1.3e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase CENP-T_C PF15511.6 KPI39415.1 - 4.2e-07 30.0 0.1 1e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KPI39415.1 - 3.2e-05 24.3 0.2 4e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KPI39415.1 - 8.7e-05 22.6 0.2 0.00013 22.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KPI39415.1 - 0.00022 21.5 0.1 0.00037 20.7 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KPI39415.1 - 0.00088 19.6 0.1 0.0016 18.8 0.1 1.6 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KPI39415.1 - 0.0063 16.6 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KPI39415.1 - 0.016 15.2 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HIGH_NTase1_ass PF16581.5 KPI39415.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Abhydrolase_1 PF00561.20 KPI39416.1 - 1.5e-08 34.6 0.4 9.5e-06 25.4 0.4 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI39416.1 - 1.7e-07 32.1 0.4 6e-07 30.3 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI39416.1 - 1.9e-06 27.3 0.0 0.042 13.1 0.0 3.2 2 1 1 3 3 3 3 Serine aminopeptidase, S33 UCH PF00443.29 KPI39417.1 - 1.4e-37 129.6 0.0 2.4e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 KPI39417.1 - 8.4e-30 103.8 1.2 1.9e-29 102.7 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH_1 PF13423.6 KPI39417.1 - 7.1e-22 78.4 0.1 4.4e-21 75.8 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase dsRBD2 PF17842.1 KPI39417.1 - 0.1 12.8 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Citrus_P18 PF05520.11 KPI39418.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Anophelin PF10731.9 KPI39420.1 - 0.12 12.3 1.0 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Mito_carr PF00153.27 KPI39421.1 - 9.7e-46 153.6 3.8 5.1e-16 58.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIFIN PF02009.16 KPI39422.1 - 0.89 9.4 7.6 1.3 8.8 7.6 1.1 1 0 0 1 1 1 0 Rifin P5CR_dimer PF14748.6 KPI39423.1 - 3.9e-34 117.0 2.0 6.9e-34 116.2 2.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KPI39423.1 - 9.9e-12 45.3 0.8 6.8e-10 39.4 0.0 3.2 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_4 PF01565.23 KPI39424.1 - 7.9e-29 100.2 2.5 1.3e-28 99.5 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI39424.1 - 4e-12 46.0 0.2 9.8e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_11 PF08241.12 KPI39425.1 - 3.9e-13 49.9 0.0 1.1e-12 48.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI39425.1 - 8.1e-13 48.9 0.0 1.6e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39425.1 - 1.2e-09 38.8 0.0 6.3e-09 36.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39425.1 - 6.7e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI39425.1 - 5.6e-06 26.3 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KPI39425.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 KPI39425.1 - 0.2 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) VHS PF00790.19 KPI39426.1 - 2.4e-33 115.0 1.0 4.7e-33 114.0 1.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KPI39426.1 - 2.2e-16 59.2 0.0 5.5e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI39426.1 - 1.3e-14 53.8 0.1 3.1e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI39426.1 - 7.9e-14 51.1 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KPI39426.1 - 1.1e-09 38.5 1.8 1.1e-09 38.5 1.8 1.9 2 0 0 2 2 2 1 GAT domain dCMP_cyt_deam_1 PF00383.23 KPI39427.1 - 2.3e-26 91.6 1.4 3.3e-26 91.1 1.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPI39427.1 - 1.6e-10 40.8 0.1 3e-10 40.0 0.1 1.4 1 1 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KPI39427.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkr1 PF08636.10 KPI39428.1 - 3.7e-30 103.9 4.3 4.8e-30 103.5 4.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 IncD PF17628.2 KPI39428.1 - 0.064 13.0 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D Kei1 PF08552.11 KPI39428.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SWIRM-assoc_2 PF16496.5 KPI39428.1 - 0.51 9.2 3.6 0.62 8.9 3.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Cofilin_ADF PF00241.20 KPI39429.1 - 2.8e-26 91.7 0.0 2.6e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein BAG6 PF12057.8 KPI39430.1 - 0.0025 17.5 0.2 0.0097 15.6 0.2 2.0 1 0 0 1 1 1 1 BCL2-associated athanogene 6 Mto2_bdg PF12808.7 KPI39430.1 - 0.008 16.5 1.1 0.008 16.5 1.1 5.0 3 2 3 6 6 6 1 Micro-tubular organiser Mto1 C-term Mto2-binding region RabGAP-TBC PF00566.18 KPI39431.1 - 3.2e-51 174.1 0.0 4.6e-49 167.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain An_peroxidase PF03098.15 KPI39432.1 - 1.2e-33 116.6 0.0 3e-21 75.6 0.0 4.0 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KPI39432.1 - 4.6e-08 32.3 0.0 1.1e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Zip PF02535.22 KPI39433.1 - 1.2e-25 90.4 5.0 9.3e-18 64.5 1.6 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter SepZ PF06066.11 KPI39433.1 - 0.063 13.5 0.5 0.19 12.0 0.5 1.8 1 0 0 1 1 1 0 SepZ Yippee-Mis18 PF03226.14 KPI39434.1 - 3.1e-21 75.6 0.2 5.3e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RGCC PF15151.6 KPI39434.1 - 0.67 10.2 3.9 1.1 9.5 2.8 1.8 2 0 0 2 2 2 0 Response gene to complement 32 protein family RIG-I_C-RD PF11648.8 KPI39434.1 - 0.74 10.1 2.7 12 6.2 0.7 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Pkinase PF00069.25 KPI39435.1 - 5.4e-29 101.4 0.0 1.6e-23 83.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39435.1 - 4.1e-14 52.5 0.0 3.6e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KPI39435.1 - 0.0046 16.9 0.9 0.011 15.7 0.6 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPI39435.1 - 0.046 12.7 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KPI39435.1 - 0.052 12.5 0.0 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KPI39435.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Homeobox_KN PF05920.11 KPI39436.1 - 2.5e-20 72.1 0.8 4.9e-20 71.2 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KPI39436.1 - 2.5e-06 27.2 0.3 4.6e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Homeodomain KCH PF16944.5 KPI39437.1 - 2.3e-93 312.6 1.7 2.7e-93 312.4 1.7 1.0 1 0 0 1 1 1 1 Fungal potassium channel Rad21_Rec8_N PF04825.13 KPI39439.1 - 2.9e-35 120.7 0.1 5.4e-35 119.9 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KPI39439.1 - 1.1e-08 34.2 0.0 2.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein EF-hand_1 PF00036.32 KPI39440.1 - 1.4e-41 136.9 12.3 8.5e-10 37.5 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KPI39440.1 - 5.7e-36 122.8 5.8 4.4e-19 68.7 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KPI39440.1 - 1.6e-35 120.7 11.9 2.6e-15 56.0 0.6 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KPI39440.1 - 4e-31 104.3 7.8 9.9e-10 37.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KPI39440.1 - 8.1e-26 88.3 10.2 3.4e-06 26.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KPI39440.1 - 2.2e-16 59.9 0.3 3.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KPI39440.1 - 3.8e-09 36.9 0.2 0.0017 18.6 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KPI39440.1 - 4.4e-09 36.2 1.8 0.00079 19.3 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 KPI39440.1 - 1.3e-06 28.4 0.1 0.0087 16.1 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KPI39440.1 - 4.6e-06 26.6 1.3 2.6e-05 24.2 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KPI39440.1 - 0.0001 23.1 0.2 0.0025 18.6 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KPI39440.1 - 0.00015 21.7 1.2 0.38 10.7 0.0 2.6 1 1 2 3 3 3 2 Tellurite resistance protein TerB Caleosin PF05042.13 KPI39440.1 - 0.00059 19.8 1.6 0.51 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KPI39440.1 - 0.00061 20.1 0.8 0.6 10.4 0.2 2.8 2 1 0 2 2 2 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 KPI39440.1 - 0.0065 16.6 6.9 0.43 10.8 0.8 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF5580 PF17743.1 KPI39440.1 - 0.0068 15.0 0.0 0.007 15.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KPI39440.1 - 0.011 15.6 0.9 0.41 10.5 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 KPI39440.1 - 0.014 15.7 0.4 7.1 7.1 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KPI39440.1 - 0.027 14.7 0.0 0.2 11.9 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KPI39440.1 - 0.052 14.0 0.0 9.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) dCache_2 PF08269.11 KPI39440.1 - 0.066 12.4 0.1 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Cache domain RuvA_C PF07499.13 KPI39440.1 - 0.071 13.6 0.1 9.3 6.8 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KPI39440.1 - 0.071 13.2 0.2 1.4 9.1 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RloB PF13707.6 KPI39440.1 - 0.16 12.1 1.0 0.79 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KPI39440.1 - 0.17 12.0 0.5 22 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) DUF3500 PF12006.8 KPI39441.1 - 6.5e-106 354.1 0.0 8.7e-106 353.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) p450 PF00067.22 KPI39442.1 - 3.5e-57 194.2 0.0 4.1e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF747 PF05346.11 KPI39443.1 - 6.6e-116 387.2 6.0 8.9e-116 386.8 6.0 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family TMEM154 PF15102.6 KPI39443.1 - 0.19 11.6 0.4 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Methyltransf_23 PF13489.6 KPI39444.1 - 1.2e-09 38.3 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI39444.1 - 1.3e-09 38.6 0.0 2.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39444.1 - 1.6e-05 24.7 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KPI39444.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KPI39444.1 - 0.0023 18.6 0.0 0.0076 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39444.1 - 0.0038 17.9 0.0 0.0058 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPI39444.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KPI39444.1 - 0.013 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KPI39444.1 - 0.048 13.2 0.0 0.16 11.5 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase small domain GMC_oxred_N PF00732.19 KPI39445.1 - 5.1e-48 163.9 0.0 7.2e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI39445.1 - 3.8e-34 118.3 0.0 6.2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KPI39445.1 - 0.00024 21.3 0.2 0.00063 19.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI39445.1 - 0.00028 20.6 3.6 0.0023 17.6 2.1 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI39445.1 - 0.0013 18.0 0.1 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KPI39445.1 - 0.0014 17.7 0.1 0.0027 16.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KPI39445.1 - 0.0095 15.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI39445.1 - 0.011 15.0 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI39445.1 - 0.025 14.6 1.5 0.27 11.2 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPI39445.1 - 0.058 12.6 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KPI39445.1 - 0.083 11.6 0.1 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 KPI39445.1 - 0.094 11.9 0.0 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI39445.1 - 0.13 11.3 0.3 0.75 8.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain DHC_N2 PF08393.13 KPI39446.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 CRIM PF16978.5 KPI39447.1 - 4.7e-38 130.5 0.0 8.3e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KPI39447.1 - 2.6e-16 59.8 0.1 4.8e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KPI39447.1 - 0.0029 17.8 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain MRC1 PF09444.10 KPI39447.1 - 0.045 14.3 1.9 0.14 12.7 1.9 1.8 1 0 0 1 1 1 0 MRC1-like domain TFIIF_alpha PF05793.12 KPI39447.1 - 2.5 6.6 6.1 4 5.9 6.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3328 PF11807.8 KPI39450.1 - 3.9e-24 85.6 0.9 3e-23 82.8 0.9 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Metal_resist PF13801.6 KPI39450.1 - 0.031 14.5 0.1 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 Heavy-metal resistance Rad17 PF03215.15 KPI39451.1 - 1.1e-18 67.8 0.0 3.1e-18 66.4 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KPI39451.1 - 0.00015 22.2 0.1 0.00049 20.5 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KPI39451.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPI39451.1 - 0.0054 15.8 0.1 0.013 14.6 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KPI39451.1 - 0.0074 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KPI39451.1 - 0.016 15.5 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPI39451.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI39451.1 - 0.073 13.1 0.0 0.21 11.6 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pkinase PF00069.25 KPI39452.1 - 5.7e-71 239.0 0.0 7.1e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39452.1 - 1.4e-38 132.6 0.0 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI39452.1 - 3.4e-06 26.6 0.1 6.8e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KPI39452.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ammonium_transp PF00909.21 KPI39453.1 - 2.2e-93 313.1 33.2 2.4e-93 313.0 30.7 1.8 1 1 1 2 2 2 2 Ammonium Transporter Family Bac_rhamnosid6H PF17389.2 KPI39454.1 - 1.8e-21 76.8 0.1 3e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 KPI39454.1 - 0.00077 18.3 0.1 0.0012 17.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid_N PF08531.10 KPI39454.1 - 0.0033 17.3 0.0 0.03 14.1 0.0 2.1 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 KPI39454.1 - 0.016 15.1 0.0 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain ATP_transf PF09830.9 KPI39455.1 - 6.6e-12 45.4 0.0 7.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ATP adenylyltransferase Exo_endo_phos PF03372.23 KPI39456.1 - 2.9e-14 53.1 0.0 9.4e-14 51.5 0.0 1.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF5345 PF17280.2 KPI39456.1 - 0.099 12.6 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) WW PF00397.26 KPI39458.1 - 0.068 13.3 5.3 0.78 9.9 5.3 2.5 1 1 0 1 1 1 0 WW domain FAA_hydro_N_2 PF18288.1 KPI39458.1 - 0.13 12.7 1.8 21 5.6 0.1 3.4 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF1932 PF09130.11 KPI39459.1 - 3e-21 75.1 0.0 6.3e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KPI39459.1 - 1.6e-07 31.6 0.0 3.9e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPI39459.1 - 1.4e-05 25.6 0.0 3.7e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPI39459.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Serglycin PF04360.12 KPI39459.1 - 0.03 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Serglycin DEDD_Tnp_IS110 PF01548.17 KPI39459.1 - 0.039 13.8 0.2 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 Transposase 3HCDH_N PF02737.18 KPI39459.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PH PF00169.29 KPI39460.1 - 0.016 15.7 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 PH domain Mito_carr PF00153.27 KPI39461.1 - 1.5e-67 223.6 3.2 9.6e-24 83.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clathrin_lg_ch PF01086.17 KPI39462.1 - 1.1e-56 192.5 10.7 2.1e-54 185.0 10.7 2.0 1 1 0 1 1 1 1 Clathrin light chain Complex1_LYR_2 PF13233.6 KPI39463.1 - 3.4e-19 69.4 0.7 5.9e-19 68.6 0.7 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KPI39463.1 - 4.8e-09 36.1 0.1 8.2e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PTPA PF03095.15 KPI39464.1 - 2.1e-113 378.8 0.0 2.4e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Carboxyl_trans PF01039.22 KPI39465.1 - 3.3e-74 250.3 0.0 5.9e-74 249.5 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain FAA_hydro_N_2 PF18288.1 KPI39465.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF1899 PF08953.11 KPI39467.1 - 3.5e-33 113.3 0.0 6.4e-33 112.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KPI39467.1 - 1.7e-20 72.6 0.3 3.6e-20 71.6 0.3 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KPI39467.1 - 7.3e-13 48.8 6.3 0.0018 19.0 0.2 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39467.1 - 0.0023 18.2 0.0 0.12 12.7 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DivIC PF04977.15 KPI39467.1 - 0.042 13.6 1.8 0.076 12.8 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator BiPBP_C PF06832.12 KPI39467.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Sec2p PF06428.11 KPI39467.1 - 0.12 12.3 0.9 0.23 11.5 0.9 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 KPI39467.1 - 0.17 12.0 3.0 0.26 11.4 3.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KPI39467.1 - 0.72 10.5 2.5 1.8 9.3 2.5 1.6 1 0 0 1 1 1 0 SlyX DUF3818 PF12825.7 KPI39468.1 - 2.5e-50 171.4 1.4 1.3e-29 103.3 0.6 2.6 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KPI39468.1 - 1.6e-30 105.8 0.0 3e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 PX-associated IL34 PF15036.6 KPI39468.1 - 0.003 17.6 0.0 0.068 13.2 0.0 2.3 2 0 0 2 2 2 1 Interleukin 34 Metal_resist PF13801.6 KPI39468.1 - 0.033 14.4 1.0 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 Heavy-metal resistance NdhM PF10664.9 KPI39468.1 - 0.054 13.8 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DUF3106 PF11304.8 KPI39468.1 - 0.68 10.4 3.0 5.7 7.5 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) SSrecog PF03531.14 KPI39470.1 - 4.3e-30 103.4 0.0 6.7e-29 99.6 0.0 2.7 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KPI39470.1 - 3.5e-27 94.7 0.6 5.9e-25 87.5 0.1 3.2 4 0 0 4 4 4 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KPI39470.1 - 5.6e-25 87.6 0.0 8.4e-24 83.8 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like NOA36 PF06524.12 KPI39470.1 - 7.1 5.9 10.7 10 5.3 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein Aldolase_II PF00596.21 KPI39472.1 - 5e-40 137.4 1.6 1.6e-39 135.7 1.7 1.8 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.8 KPI39472.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Pyr_redox_3 PF13738.6 KPI39473.1 - 9.4e-15 54.6 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI39473.1 - 5.8e-08 31.6 0.0 1.2e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI39473.1 - 6.5e-08 32.2 0.0 3.3e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI39473.1 - 2.9e-06 26.7 0.0 8.6e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPI39473.1 - 3.7e-05 23.1 0.0 0.00029 20.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KPI39473.1 - 4.9e-05 23.4 0.2 0.00068 19.7 0.2 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI39473.1 - 0.0021 18.2 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI39473.1 - 0.0074 15.4 0.0 0.013 14.6 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KPI39473.1 - 0.038 12.7 0.0 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Hyccin PF09790.9 KPI39473.1 - 0.26 10.4 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Hyccin HET PF06985.11 KPI39474.1 - 6e-30 104.5 2.6 9.2e-30 103.9 2.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 KPI39475.1 - 0.0039 17.0 2.1 0.78 9.7 0.1 2.9 3 0 0 3 3 3 2 F-box domain Zip PF02535.22 KPI39476.1 - 1.6e-16 60.5 2.0 1.9e-16 60.2 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Oxidored_FMN PF00724.20 KPI39477.1 - 7.1e-38 130.7 0.0 2.1e-36 125.9 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family muHD PF10291.9 KPI39478.1 - 0.048 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain PSP PF04046.16 KPI39478.1 - 0.26 11.2 0.9 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 PSP Pol_alpha_B_N PF08418.10 KPI39478.1 - 0.96 9.4 6.2 1.4 8.8 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Med13_C PF06333.12 KPI39479.1 - 1.5e-65 221.7 0.0 1.5e-65 221.7 0.0 3.0 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KPI39479.1 - 1.7e-43 149.2 0.1 3e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KPI39479.1 - 2e-13 50.7 0.2 9.1e-06 25.6 0.0 2.6 1 1 0 2 2 2 2 MID domain of medPIWI Glyco_transf_28 PF03033.20 KPI39480.1 - 1.2e-16 61.0 0.1 2.2e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KPI39480.1 - 1.6e-06 28.2 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KPI39480.1 - 0.00012 21.1 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KPI39480.1 - 0.0039 17.5 0.0 0.1 13.0 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain FAD_binding_1 PF00667.20 KPI39481.1 - 3e-60 203.5 0.1 8e-60 202.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KPI39481.1 - 2e-10 41.2 0.0 9.6e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.18 KPI39481.1 - 2.9e-09 37.3 0.2 6.8e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KPI39481.1 - 8.8e-06 26.0 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KPI39481.1 - 9.1e-05 22.3 0.0 0.00043 20.1 0.0 2.2 3 0 0 3 3 3 1 Transketolase, C-terminal domain POR_N PF01855.19 KPI39481.1 - 0.015 15.1 0.4 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF3738 PF12543.8 KPI39481.1 - 0.015 15.5 0.1 0.04 14.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3738) Usp PF00582.26 KPI39481.1 - 0.57 10.7 3.8 15 6.1 0.3 3.4 3 0 0 3 3 3 0 Universal stress protein family HMG_box PF00505.19 KPI39483.1 - 3.4e-06 27.4 0.4 7.3e-06 26.3 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Coiled-coil_56 PF09813.9 KPI39483.1 - 0.044 13.8 2.7 0.28 11.3 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF3987 PF13148.6 KPI39483.1 - 0.39 9.7 5.0 0.062 12.3 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SOG2 PF10428.9 KPI39483.1 - 0.4 9.8 10.4 0.48 9.6 10.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AAT PF03417.16 KPI39484.1 - 1.4e-07 31.5 0.0 1.5e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans PF04082.18 KPI39485.1 - 2e-13 50.0 0.3 3.3e-13 49.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GAIN_A PF18619.1 KPI39485.1 - 0.034 14.4 0.5 0.1 12.8 0.5 1.8 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A GET2 PF08690.10 KPI39485.1 - 0.068 12.8 0.8 0.12 12.0 0.8 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 TilS PF09179.11 KPI39485.1 - 0.15 12.6 1.7 3.5 8.2 0.2 3.3 3 0 0 3 3 3 0 TilS substrate binding domain AA_permease_2 PF13520.6 KPI39486.1 - 9.4e-58 196.0 32.2 2.1e-53 181.7 25.0 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPI39486.1 - 1.1e-17 63.8 30.4 2.4e-17 62.7 30.4 1.4 1 1 0 1 1 1 1 Amino acid permease PepSY_TM PF03929.16 KPI39486.1 - 0.92 9.1 7.9 4.1 7.0 1.1 2.6 2 1 0 2 2 2 0 PepSY-associated TM region SnoaL_2 PF12680.7 KPI39487.1 - 9.2e-05 23.0 0.3 0.00025 21.6 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain DLH PF01738.18 KPI39487.1 - 0.00045 19.8 0.1 0.063 12.8 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family SnoaL PF07366.12 KPI39487.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase TRI12 PF06609.13 KPI39488.1 - 3.5e-77 260.2 25.1 4.3e-77 259.9 25.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI39488.1 - 6.6e-26 91.1 81.1 2e-24 86.2 49.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5378 PF17349.2 KPI39488.1 - 0.0044 16.4 0.2 0.0044 16.4 0.2 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5378) Pox_A14 PF05767.12 KPI39488.1 - 0.24 11.6 0.2 0.24 11.6 0.2 3.0 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Pex24p PF06398.11 KPI39488.1 - 0.44 9.5 4.3 0.6 9.0 2.8 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin HD PF01966.22 KPI39489.1 - 0.003 17.8 0.9 0.013 15.7 0.9 2.0 1 1 0 1 1 1 1 HD domain Abhydrolase_1 PF00561.20 KPI39490.1 - 1.5e-24 87.1 0.2 3.8e-19 69.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI39490.1 - 9.1e-22 78.7 0.0 1.6e-21 77.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI39490.1 - 1.6e-11 43.9 0.0 2e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KPI39490.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) tRNA-synt_1d PF00750.19 KPI39491.1 - 2e-90 303.2 8.5 4.2e-90 302.2 8.5 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KPI39491.1 - 1.6e-30 105.8 0.1 3.6e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KPI39491.1 - 1.1e-05 25.9 0.0 4.9e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GFA PF04828.14 KPI39492.1 - 2.4e-09 37.4 1.0 2.4e-09 37.4 1.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Questin_oxidase PF14027.6 KPI39493.1 - 2.3e-69 234.5 0.0 3.6e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like Ferritin_2 PF13668.6 KPI39493.1 - 3.1e-20 72.7 14.4 1.9e-12 47.6 2.2 3.2 2 1 1 3 3 3 2 Ferritin-like domain QWRF PF04484.12 KPI39493.1 - 6.6 6.4 6.5 10 5.8 6.5 1.2 1 0 0 1 1 1 0 QWRF family GFA PF04828.14 KPI39494.1 - 2.6e-25 88.6 7.2 1.8e-13 50.6 0.1 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme VWA_N2 PF16164.5 KPI39494.1 - 0.014 15.5 0.2 2.3 8.4 0.1 3.0 2 0 0 2 2 2 0 VWA N-terminal NOB1_Zn_bind PF08772.11 KPI39494.1 - 0.056 13.6 7.1 1.5 9.1 0.1 2.7 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.16 KPI39494.1 - 0.72 9.8 0.0 0.72 9.8 0.0 4.2 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Rpr2 PF04032.16 KPI39494.1 - 4.4 7.7 8.7 9.6 6.6 0.0 3.3 4 0 0 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Lyase_1 PF00206.20 KPI39495.1 - 9.9e-26 90.9 0.0 1.3e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FtsX PF02687.21 KPI39496.1 - 6.6 7.3 7.8 11 6.6 0.1 3.1 3 0 0 3 3 3 0 FtsX-like permease family TAF4 PF05236.14 KPI39497.1 - 0.071 12.8 0.2 0.08 12.7 0.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2976 PF11190.8 KPI39498.1 - 0.059 13.2 0.2 0.099 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Myc_target_1 PF15179.6 KPI39498.1 - 0.11 12.4 3.4 0.25 11.2 0.7 2.3 2 1 0 2 2 2 0 Myc target protein 1 Trypan_PARP PF05887.11 KPI39499.1 - 3.9e-07 30.1 14.6 8.8e-07 29.0 14.6 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) F-box PF00646.33 KPI39499.1 - 0.018 14.9 1.0 0.048 13.6 1.0 1.7 1 0 0 1 1 1 0 F-box domain GST_N_3 PF13417.6 KPI39500.1 - 1.4e-17 63.9 0.0 1.5e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI39500.1 - 9.7e-15 54.6 0.0 8.2e-14 51.7 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI39500.1 - 4.9e-08 33.2 0.2 1.7e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI39500.1 - 0.00011 22.1 0.4 0.002 18.1 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KPI39500.1 - 0.0079 16.8 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KPI39500.1 - 0.035 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin adh_short_C2 PF13561.6 KPI39501.1 - 1.3e-28 100.2 0.6 4.3e-28 98.5 0.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI39501.1 - 3.7e-27 95.0 6.4 4e-26 91.7 6.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI39501.1 - 0.00098 19.1 0.2 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 KR domain Dak1 PF02733.17 KPI39501.1 - 0.059 12.3 2.2 2.2 7.1 0.5 2.4 1 1 1 2 2 2 0 Dak1 domain SnoaL PF07366.12 KPI39502.1 - 3.8e-19 68.7 0.1 4.6e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPI39502.1 - 7.8e-12 45.7 0.7 1.1e-11 45.2 0.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF3431 PF11913.8 KPI39503.1 - 9.6e-62 208.6 0.3 1.2e-61 208.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Cation_ATPase_C PF00689.21 KPI39505.1 - 3 7.5 8.4 4.7 6.9 8.1 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus STE2 PF02116.15 KPI39505.1 - 9.1 5.5 15.8 9.4 5.5 12.5 2.0 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR Putative_PNPOx PF01243.20 KPI39506.1 - 4.8e-07 29.9 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 KPI39506.1 - 0.017 15.8 0.0 0.13 13.0 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KPI39506.1 - 0.075 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain zf-C3HC4 PF00097.25 KPI39507.1 - 2.5e-07 30.5 7.0 7.3e-07 29.0 7.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI39507.1 - 6.5e-07 29.1 5.3 6.5e-07 29.1 5.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI39507.1 - 4e-06 26.7 5.6 9.5e-06 25.5 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPI39507.1 - 1.5e-05 25.2 9.6 2.6e-05 24.5 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 KPI39507.1 - 1.7e-05 24.6 1.4 3.6e-05 23.5 1.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KPI39507.1 - 6.3e-05 23.0 5.3 0.00014 22.0 5.3 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KPI39507.1 - 0.00074 19.3 6.9 0.0065 16.3 6.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI39507.1 - 0.0017 18.2 7.9 0.0037 17.2 7.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPI39507.1 - 0.074 12.9 5.2 0.36 10.7 5.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KPI39507.1 - 0.17 12.1 4.9 2.9 8.1 4.9 2.2 1 1 0 1 1 1 0 zinc RING finger of MSL2 Tmpp129 PF10272.9 KPI39507.1 - 0.4 9.9 2.5 0.68 9.2 2.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Zn_ribbon_17 PF17120.5 KPI39507.1 - 0.65 9.7 3.8 1.7 8.4 3.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KPI39507.1 - 3.6 7.7 5.5 19 5.3 5.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF4778 PF16008.5 KPI39507.1 - 4.8 7.2 11.5 8.2 6.4 11.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) CEBP_ZZ PF16366.5 KPI39507.1 - 8.6 6.7 10.2 3 8.1 6.0 2.2 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain MLANA PF14991.6 KPI39508.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A RIFIN PF02009.16 KPI39508.1 - 0.013 15.4 1.1 0.013 15.4 1.1 1.4 2 0 0 2 2 2 0 Rifin EphA2_TM PF14575.6 KPI39508.1 - 0.018 15.9 0.0 0.029 15.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KPI39508.1 - 0.027 13.9 4.3 0.053 12.9 4.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmD PF04995.14 KPI39508.1 - 0.046 13.8 0.5 0.076 13.1 0.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TMEM154 PF15102.6 KPI39508.1 - 0.15 11.9 1.4 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family GT87 PF09594.10 KPI39508.1 - 0.16 11.7 1.6 0.22 11.2 1.6 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 Amnionless PF14828.6 KPI39508.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF2701 PF10857.8 KPI39508.1 - 0.18 11.9 0.4 0.28 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) Stevor PF17410.2 KPI39508.1 - 0.24 10.9 0.8 0.36 10.3 0.8 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2477 PF10631.9 KPI39508.1 - 0.25 12.0 1.1 0.42 11.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) DUF347 PF03988.12 KPI39508.1 - 0.62 10.3 4.0 1.4 9.2 4.1 1.7 1 1 1 2 2 2 0 Repeat of Unknown Function (DUF347) ABC_membrane PF00664.23 KPI39509.1 - 2e-48 165.5 9.2 2.6e-48 165.1 9.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPI39509.1 - 7.8e-35 120.4 0.0 1.9e-34 119.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KPI39509.1 - 2.9e-07 30.2 1.3 4.9e-05 22.9 0.0 3.0 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPI39509.1 - 0.0057 17.1 0.2 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI39509.1 - 0.0059 16.9 0.1 0.026 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KPI39509.1 - 0.0076 16.7 0.0 0.028 14.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KPI39509.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KPI39509.1 - 0.025 14.3 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KPI39509.1 - 0.11 12.1 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPI39509.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 KPI39509.1 - 0.15 11.8 0.1 1.5 8.5 0.1 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 KPI39509.1 - 2.4 8.4 6.9 1.3 9.3 1.4 3.1 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Myb_DNA-bind_2 PF08914.11 KPI39510.1 - 4.3e-15 55.6 0.8 6e-14 52.0 0.3 2.5 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 KPI39510.1 - 1.2e-12 47.7 0.1 4.9e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain GATA PF00320.27 KPI39510.1 - 6.7e-06 25.6 6.0 6.7e-06 25.6 6.0 2.1 2 0 0 2 2 2 1 GATA zinc finger BRCT_2 PF16589.5 KPI39510.1 - 0.00063 20.1 0.0 0.0016 18.8 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 KPI39510.1 - 0.002 18.3 1.4 1 9.6 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1-DNA-bind PF09197.10 KPI39510.1 - 0.0025 18.4 1.0 0.013 16.1 0.0 2.6 2 0 0 2 2 2 1 Rap1, DNA-binding Herpes_TK_C PF08465.10 KPI39510.1 - 0.12 12.1 0.8 0.68 9.7 0.2 2.3 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal DUF1330 PF07045.11 KPI39511.1 - 0.0033 17.7 0.2 2.3 8.6 0.0 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF1330) Glyco_hydro_cc PF11790.8 KPI39512.1 - 2.8e-59 200.6 0.3 3.4e-59 200.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WD40 PF00400.32 KPI39514.1 - 4.7e-41 138.0 21.0 1.4e-07 32.1 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KPI39514.1 - 2.3e-13 49.8 0.4 4.1e-13 49.0 0.4 1.4 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KPI39514.1 - 9.1e-12 45.1 0.8 0.016 15.5 0.0 5.9 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPI39514.1 - 2.1e-05 24.0 0.0 0.0048 16.3 0.0 2.9 1 1 3 4 4 4 2 WD40-like domain Nup160 PF11715.8 KPI39514.1 - 6.1e-05 21.9 4.9 2.6 6.6 0.0 5.5 1 1 5 6 6 6 2 Nucleoporin Nup120/160 F-box PF00646.33 KPI39514.1 - 7.9e-05 22.4 1.8 0.00017 21.4 1.8 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KPI39514.1 - 0.012 15.1 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 F-box PQQ_2 PF13360.6 KPI39514.1 - 0.026 14.1 2.8 0.39 10.2 0.8 2.8 1 1 1 2 2 2 0 PQQ-like domain Mcl1_mid PF12341.8 KPI39514.1 - 0.035 13.5 0.1 1.2 8.5 0.2 2.8 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region TFIIE_alpha PF02002.17 KPI39515.1 - 3e-07 30.3 0.2 7.6e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.14 KPI39515.1 - 0.095 12.6 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Med7 PF05983.11 KPI39516.1 - 9.2e-37 127.0 0.5 1.4e-36 126.4 0.5 1.3 1 0 0 1 1 1 1 MED7 protein DUF3846 PF12957.7 KPI39516.1 - 0.14 12.5 0.1 0.77 10.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) Haspin_kinase PF12330.8 KPI39517.1 - 5.3e-25 88.1 0.0 4.9e-24 84.9 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain NUC153 PF08159.12 KPI39519.1 - 8.1e-10 38.3 3.3 1.1e-09 37.9 1.2 2.2 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 KPI39519.1 - 0.067 14.1 0.3 71 4.5 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Fungal_trans PF04082.18 KPI39520.1 - 1.8e-12 46.9 0.0 4.7e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cpn60_TCP1 PF00118.24 KPI39521.1 - 3.3e-132 441.6 9.6 4e-132 441.3 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RXT2_N PF08595.11 KPI39521.1 - 0.098 12.7 2.1 0.21 11.6 1.1 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal RFamide_26RFa PF11109.8 KPI39521.1 - 0.12 12.9 0.3 0.34 11.4 0.3 1.7 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 FAM176 PF14851.6 KPI39521.1 - 0.66 9.6 3.7 1.7 8.3 3.7 1.6 1 0 0 1 1 1 0 FAM176 family Cupin_2 PF07883.11 KPI39522.1 - 1.5e-12 47.0 0.8 2e-08 33.8 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KPI39522.1 - 0.00059 19.5 0.2 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Ppnp PF06865.11 KPI39522.1 - 0.0026 18.1 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase AraC_binding PF02311.19 KPI39522.1 - 0.005 16.7 0.0 0.027 14.4 0.1 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain GatD_N PF18195.1 KPI39522.1 - 0.0098 15.2 0.0 2.5 7.5 0.0 2.5 2 0 0 2 2 2 2 GatD N-terminal domain MannoseP_isomer PF01050.18 KPI39522.1 - 0.04 13.8 0.0 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 KPI39522.1 - 0.18 11.2 1.4 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Bromodomain PF00439.25 KPI39524.1 - 5.5e-19 68.0 0.4 1.4e-18 66.8 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KPI39524.1 - 1.6e-05 24.8 0.0 4.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated DAGAT PF03982.13 KPI39525.1 - 2.9e-94 315.3 0.0 3.8e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Filament PF00038.21 KPI39526.1 - 4.8e-05 23.1 1.2 6.2e-05 22.7 1.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein LXG PF04740.12 KPI39526.1 - 0.0068 16.1 0.8 0.01 15.5 0.8 1.3 1 0 0 1 1 1 1 LXG domain of WXG superfamily FCH PF00611.23 KPI39526.1 - 0.011 16.1 0.1 0.025 14.9 0.1 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain CpxA_peri PF16527.5 KPI39526.1 - 0.052 13.9 0.5 0.091 13.1 0.4 1.5 1 1 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain Apolipoprotein PF01442.18 KPI39526.1 - 0.38 10.6 6.2 2.7 7.9 6.2 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain F-box PF00646.33 KPI39527.1 - 0.003 17.4 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain HMG_box_5 PF14887.6 KPI39527.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 F-box-like PF12937.7 KPI39527.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 F-box-like CFEM PF05730.11 KPI39528.1 - 1.6e-05 24.9 3.6 4e-05 23.6 3.6 1.7 1 1 0 1 1 1 1 CFEM domain DUF1180 PF06679.12 KPI39528.1 - 1.6 9.1 5.3 2.3 8.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Catalase PF00199.19 KPI39529.1 - 1.4e-117 393.0 0.0 1.9e-117 392.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KPI39529.1 - 3.2e-21 75.6 1.1 3.2e-21 75.6 1.1 1.9 2 0 0 2 2 2 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KPI39529.1 - 1.7e-11 44.2 0.1 4.3e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Macoilin PF09726.9 KPI39532.1 - 0.31 9.6 5.5 0.32 9.5 5.5 1.2 1 0 0 1 1 1 0 Macoilin family Pirin PF02678.16 KPI39533.1 - 1.8e-24 85.8 1.8 6.4e-24 84.0 1.8 1.9 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KPI39533.1 - 2.5e-06 27.1 3.6 5e-05 22.9 1.0 3.1 2 1 0 2 2 2 1 Cupin domain 2OG-FeII_Oxy PF03171.20 KPI39533.1 - 0.081 13.4 0.1 0.29 11.7 0.1 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3394 PF11874.8 KPI39533.1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Hydantoinase_B PF02538.14 KPI39534.1 - 2.8e-127 425.2 0.0 1.2e-126 423.2 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KPI39534.1 - 4.3e-94 315.0 5.0 1.4e-93 313.4 2.5 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KPI39534.1 - 2.5e-48 164.1 3.3 1e-46 158.9 0.0 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region FtsA PF14450.6 KPI39534.1 - 0.00044 20.6 0.2 2 8.9 0.0 2.9 3 0 0 3 3 3 2 Cell division protein FtsA MutL PF13941.6 KPI39534.1 - 0.011 14.4 0.3 1.4 7.4 0.0 2.3 2 0 0 2 2 2 0 MutL protein BcrAD_BadFG PF01869.20 KPI39534.1 - 0.094 12.2 0.5 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Mis12 PF05859.12 KPI39534.1 - 0.12 12.4 0.1 1.8 8.6 0.1 2.4 1 1 0 1 1 1 0 Mis12 protein AhpC-TSA PF00578.21 KPI39535.1 - 9.7e-31 106.3 0.0 1.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI39535.1 - 6.7e-14 51.8 0.0 9.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KPI39535.1 - 3.1e-12 46.1 0.2 5.5e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin CFEM PF05730.11 KPI39536.1 - 1.6e-08 34.5 6.8 2.8e-08 33.7 6.8 1.4 1 0 0 1 1 1 1 CFEM domain DUF935 PF06074.12 KPI39537.1 - 0.071 11.8 7.9 0.18 10.5 7.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Med29 PF11568.8 KPI39537.1 - 0.14 12.4 0.8 0.25 11.5 0.2 1.7 2 0 0 2 2 2 0 Mediator complex subunit 29 PYC_OADA PF02436.18 KPI39538.1 - 5.1e-68 228.7 0.0 7e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_lipoyl PF00364.22 KPI39538.1 - 3.7e-19 68.3 4.4 8.1e-19 67.2 4.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KPI39538.1 - 1.3e-11 44.1 0.9 6.7e-07 29.0 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KPI39538.1 - 2.6e-05 24.9 0.2 0.15 12.8 0.1 3.1 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 KPI39538.1 - 4.9e-05 22.7 0.2 0.026 13.8 0.1 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KPI39538.1 - 0.013 15.5 1.7 0.047 13.7 1.6 1.9 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 KPI39538.1 - 0.013 15.4 1.1 0.019 14.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 KPI39538.1 - 0.035 14.0 3.2 0.15 11.9 1.0 2.3 1 1 1 2 2 2 0 Glycine cleavage H-protein PYNP_C PF07831.13 KPI39538.1 - 0.042 13.5 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain QRPTase_N PF02749.16 KPI39538.1 - 0.086 12.9 0.2 1.7 8.7 0.1 2.4 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.22 KPI39538.1 - 0.22 11.7 0.6 0.95 9.7 0.6 2.2 1 1 0 1 1 1 0 Peptidase family M23 FAD_binding_3 PF01494.19 KPI39539.1 - 4.9e-39 134.6 0.0 6.7e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI39539.1 - 4.3e-07 29.5 0.0 0.0021 17.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI39539.1 - 6.1e-05 22.2 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPI39539.1 - 9.7e-05 22.5 0.1 0.0003 21.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI39539.1 - 0.00014 22.3 0.1 0.084 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI39539.1 - 0.00021 21.0 0.2 0.43 10.1 0.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPI39539.1 - 0.00035 20.0 0.2 0.012 14.9 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KPI39539.1 - 0.00044 19.6 0.2 0.024 13.9 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI39539.1 - 0.00089 18.1 0.2 0.016 13.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KPI39539.1 - 0.0066 15.6 0.9 0.049 12.7 0.5 2.3 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.17 KPI39539.1 - 0.027 13.7 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KPI39539.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.15 KPI39539.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 KPI39539.1 - 0.081 12.3 0.5 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase PRONE PF03759.13 KPI39539.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Aldedh PF00171.22 KPI39542.1 - 1e-164 548.5 0.1 1.1e-164 548.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyoxalase PF00903.25 KPI39543.1 - 1.6e-10 41.2 0.0 7.4e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPI39543.1 - 0.0037 17.5 0.0 0.0076 16.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.8 KPI39543.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Fe-ADH PF00465.19 KPI39544.1 - 1.9e-76 257.2 0.9 2.2e-76 257.0 0.9 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPI39544.1 - 4.4e-17 62.6 0.2 6.2e-17 62.1 0.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Vault_3 PF17795.1 KPI39544.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Major Vault Protein Repeat domain DUF1967 PF09269.11 KPI39544.1 - 0.14 12.1 0.1 0.37 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Gram_pos_anchor PF00746.21 KPI39545.1 - 0.064 13.2 0.9 0.15 12.0 0.9 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SKG6 PF08693.10 KPI39545.1 - 0.068 12.6 0.2 0.068 12.6 0.2 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CcmD PF04995.14 KPI39545.1 - 0.26 11.4 3.0 0.43 10.7 3.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Abhydrolase_1 PF00561.20 KPI39546.1 - 1.5e-26 93.6 0.1 2e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI39546.1 - 3.4e-14 52.8 0.0 9.4e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 KPI39547.1 - 1e-06 28.6 2.7 4.9e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KPI39547.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KPI39547.1 - 0.0013 18.0 0.1 0.043 13.1 0.1 2.4 1 1 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KPI39547.1 - 0.0038 16.8 0.0 0.0079 15.8 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KPI39547.1 - 0.022 15.3 0.1 0.036 14.7 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KPI39547.1 - 0.12 12.0 0.9 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative esterase DEAD PF00270.29 KPI39548.1 - 1.2e-45 155.5 0.0 4.7e-45 153.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI39548.1 - 5.7e-28 97.5 0.3 2.5e-27 95.4 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2986 PF11661.8 KPI39548.1 - 0.0002 21.8 2.1 0.00067 20.1 2.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.15 KPI39548.1 - 0.0099 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 KPI39548.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase AhpC-TSA PF00578.21 KPI39549.1 - 1.5e-24 86.3 0.0 1.9e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI39549.1 - 7.1e-18 64.7 0.0 2.1e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 Redoxin DUF899 PF05988.12 KPI39549.1 - 5.7e-07 29.3 0.0 8.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 KPI39549.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme efThoc1 PF11957.8 KPI39550.1 - 4.7e-116 388.4 0.0 5.6e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor GCR1_C PF12550.8 KPI39550.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes GST_N_2 PF13409.6 KPI39552.1 - 8.8e-19 67.6 0.0 1.8e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI39552.1 - 1.2e-09 38.1 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI39552.1 - 0.00019 21.6 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPI39552.1 - 0.02 15.3 0.0 0.78 10.2 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI39552.1 - 0.042 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UbiA PF01040.18 KPI39554.1 - 4.5e-42 144.1 15.3 8.3e-29 100.6 8.8 2.4 2 1 0 2 2 2 2 UbiA prenyltransferase family SOBP PF15279.6 KPI39554.1 - 1.6 9.3 8.8 3 8.4 8.8 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein Fig1 PF12351.8 KPI39554.1 - 8.5 6.2 8.0 1.5 8.7 1.5 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Enolase_C PF00113.22 KPI39556.1 - 5.4e-99 331.2 0.3 6.1e-99 331.0 0.3 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.6 KPI39556.1 - 1.5e-06 27.9 0.0 1.8e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KPI39556.1 - 0.046 12.9 0.7 0.12 11.5 0.6 1.7 1 1 1 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Zn_clus PF00172.18 KPI39557.1 - 2.6e-05 24.2 6.4 4.8e-05 23.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI39557.1 - 2.7e-05 23.3 0.5 4e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI39558.1 - 3.9e-35 121.4 64.3 2.4e-29 102.4 53.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5325 PF17259.2 KPI39558.1 - 0.17 11.8 0.3 0.17 11.8 0.3 4.7 6 0 0 6 6 6 0 Family of unknown function (DUF5325) CAP PF00188.26 KPI39559.1 - 9.5e-07 29.7 0.1 9.5e-07 29.7 0.1 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family p450 PF00067.22 KPI39561.1 - 1.3e-06 27.5 0.2 3.1e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Phosphatase PF15698.5 KPI39561.1 - 0.077 12.1 0.3 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Phosphatase Cation_ATPase_C PF00689.21 KPI39562.1 - 2.7e-32 112.0 3.5 2.7e-32 112.0 3.5 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPI39562.1 - 1.6e-24 86.4 3.8 2.9e-19 69.3 0.0 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KPI39562.1 - 1.1e-19 71.5 0.1 3e-12 47.3 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPI39562.1 - 9.1e-12 44.9 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPI39562.1 - 1.8e-08 33.9 0.0 4.7e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KPI39562.1 - 0.081 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cep57_CLD_2 PF14197.6 KPI39563.1 - 0.4 10.8 5.3 0.11 12.5 0.6 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FANCL_C PF11793.8 KPI39565.1 - 0.0041 17.3 2.2 0.023 14.9 3.3 1.6 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KPI39565.1 - 0.042 14.2 7.6 0.068 13.5 7.2 1.6 1 1 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 KPI39565.1 - 0.081 13.3 1.6 2.1 8.7 0.4 2.2 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KPI39565.1 - 0.22 11.5 3.9 0.27 11.2 1.7 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 KPI39565.1 - 1.5 8.7 4.6 3.4 7.5 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger Glyco_hydro_32N PF00251.20 KPI39566.1 - 1.4e-35 123.3 0.0 2.8e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KPI39566.1 - 1.5e-23 83.5 0.1 2.7e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KPI39566.1 - 1.1 9.5 4.2 16 6.0 0.2 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Pkinase PF00069.25 KPI39567.1 - 4e-54 183.7 0.0 4.5e-53 180.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39567.1 - 5.2e-30 104.6 0.0 7.8e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI39567.1 - 0.00025 20.1 6.5 0.00086 18.4 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KPI39567.1 - 0.094 12.6 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DMRL_synthase PF00885.19 KPI39568.1 - 7.8e-49 165.1 0.0 1.2e-48 164.5 0.0 1.3 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ADK PF00406.22 KPI39569.1 - 7.9e-45 152.6 0.0 9.7e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KPI39569.1 - 3.5e-35 121.4 0.0 4.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPI39569.1 - 1.2e-10 42.0 0.0 1.7e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPI39569.1 - 4.1e-05 23.8 0.0 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KPI39569.1 - 0.0053 16.5 0.3 1.3 8.6 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KPI39569.1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 C2 PF00168.30 KPI39570.1 - 1.4e-23 83.1 0.0 9.7e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain COesterase PF00135.28 KPI39571.1 - 5.2e-59 200.5 0.0 1.9e-57 195.3 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI39571.1 - 4.9e-07 29.8 0.0 3.4e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.25 KPI39572.1 - 3.3e-20 72.4 0.0 6.5e-20 71.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39572.1 - 6.2e-09 35.8 0.0 1.9e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39572.1 - 2.7e-06 27.4 0.1 6e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI39572.1 - 0.00049 19.6 0.2 0.00097 18.7 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KPI39572.1 - 0.011 16.0 0.1 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3025 PF11227.8 KPI39572.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) AAA_26 PF13500.6 KPI39574.1 - 4.3e-20 72.4 0.0 8.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.21 KPI39574.1 - 1.3e-19 70.2 0.0 1.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III CbiA PF01656.23 KPI39574.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_membrane PF00664.23 KPI39577.1 - 1.7e-11 44.3 3.0 1.7e-11 44.3 3.0 3.4 5 0 0 5 5 5 1 ABC transporter transmembrane region ABC_tran PF00005.27 KPI39577.1 - 2e-06 28.4 0.0 4.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KPI39577.1 - 0.014 15.9 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Neurensin PF14927.6 KPI39577.1 - 0.032 13.9 1.5 2.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Neurensin T2SSE PF00437.20 KPI39577.1 - 0.05 12.7 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KPI39577.1 - 0.056 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KPI39577.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2670 PF10875.8 KPI39578.1 - 0.055 13.6 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) Lactamase_B PF00753.27 KPI39579.1 - 0.00063 19.8 4.0 0.0016 18.5 4.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI39579.1 - 0.00088 18.8 0.3 0.0018 17.8 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI39579.1 - 0.052 13.4 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DPM3 PF08285.11 KPI39580.1 - 0.73 10.1 3.1 0.9 9.8 0.3 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Lactamase_B PF00753.27 KPI39581.1 - 1.1e-09 38.6 4.8 4.6e-08 33.3 4.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI39581.1 - 0.0018 17.8 0.0 0.0038 16.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.25 KPI39582.1 - 1.9e-65 220.9 0.0 2.8e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39582.1 - 6.4e-44 150.2 0.0 1.3e-43 149.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI39582.1 - 3.8e-08 33.0 0.0 9.9e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KPI39582.1 - 1.4e-06 27.5 0.1 1.4e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KPI39582.1 - 0.026 13.9 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI39582.1 - 0.034 14.1 2.3 0.18 11.7 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family p450 PF00067.22 KPI39583.1 - 3.5e-115 385.4 0.0 3.4e-69 233.8 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 Ribosomal_S17_N PF16205.5 KPI39584.1 - 6.1e-34 116.2 0.5 9.4e-34 115.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KPI39584.1 - 8.8e-26 89.8 0.1 1.8e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 IMS PF00817.20 KPI39585.1 - 1e-43 148.9 0.6 2.1e-43 147.9 0.6 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KPI39585.1 - 5.7e-13 49.6 0.1 1.4e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KPI39585.1 - 5.4e-07 29.6 0.0 1.5e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Vps36-NZF-N PF16988.5 KPI39585.1 - 0.082 12.3 2.2 0.77 9.2 0.2 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-MIZ PF02891.20 KPI39585.1 - 0.12 12.1 0.4 0.34 10.7 0.4 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Egh16-like PF11327.8 KPI39586.1 - 1.5e-64 217.8 7.5 1.8e-64 217.6 7.5 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Fungal_trans_2 PF11951.8 KPI39587.1 - 4.9e-74 249.5 0.0 1.1e-73 248.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI39587.1 - 2.2e-07 30.9 8.7 3.6e-07 30.2 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CdvA PF18822.1 KPI39588.1 - 0.0048 16.7 0.2 0.0088 15.9 0.2 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Ribosomal_L20 PF00453.18 KPI39588.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L20 Erythro-docking PF09277.11 KPI39588.1 - 0.2 11.6 0.4 0.2 11.6 0.4 2.4 2 0 0 2 2 2 0 Erythronolide synthase, docking DUF1657 PF07870.11 KPI39588.1 - 0.38 10.7 2.2 0.62 10.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) ADH_zinc_N PF00107.26 KPI39589.1 - 2e-24 86.0 1.7 2e-24 86.0 1.7 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI39589.1 - 2.7e-22 78.7 1.6 7.4e-22 77.3 1.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI39589.1 - 1.8e-08 34.2 0.5 2.4e-08 33.7 0.5 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI39589.1 - 1.5e-07 32.5 0.1 2.4e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI39589.1 - 0.0035 17.6 0.4 0.0058 16.9 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KPI39589.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KPI39589.1 - 0.04 14.2 0.1 0.073 13.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KPI39589.1 - 0.048 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 KPI39589.1 - 0.081 12.9 0.8 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated NAD_binding_7 PF13241.6 KPI39589.1 - 0.1 13.1 1.7 0.18 12.2 1.7 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KPI39589.1 - 0.38 11.3 4.6 1.6 9.4 0.3 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LigD_N PF13298.6 KPI39590.1 - 2e-35 121.2 0.0 4.4e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) ThuA PF06283.11 KPI39591.1 - 7.3e-45 153.8 0.1 8.4e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation Translin PF01997.16 KPI39592.1 - 4.7e-57 193.3 0.0 5.4e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Translin family Alg14 PF08660.11 KPI39592.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like MFS_1 PF07690.16 KPI39593.1 - 7e-19 68.0 27.2 7e-19 68.0 27.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.21 KPI39594.1 - 3.5e-46 157.3 0.2 5e-46 156.9 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FixQ PF05545.11 KPI39594.1 - 0.069 13.1 5.3 0.13 12.2 0.2 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF347 PF03988.12 KPI39594.1 - 0.071 13.3 0.1 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) GATA PF00320.27 KPI39595.1 - 3.2e-15 55.4 5.3 5.6e-15 54.7 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KPI39595.1 - 0.41 10.9 1.6 0.83 10.0 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon ABC_tran PF00005.27 KPI39596.1 - 1.2e-46 158.7 0.4 6.1e-22 78.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KPI39596.1 - 1e-18 67.1 6.1 1e-18 67.1 6.1 3.7 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 KPI39596.1 - 4.3e-15 56.3 9.5 0.0035 17.2 0.0 4.7 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI39596.1 - 7e-11 42.0 0.2 0.018 14.5 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPI39596.1 - 6.8e-07 30.0 13.4 0.0015 19.0 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 KPI39596.1 - 2.8e-06 27.7 0.0 0.02 15.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.6 KPI39596.1 - 8.1e-06 25.5 0.5 0.16 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KPI39596.1 - 1.1e-05 25.5 0.0 0.064 13.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 KPI39596.1 - 1.7e-05 24.6 0.1 0.0067 16.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KPI39596.1 - 2.2e-05 24.9 0.4 0.12 12.7 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPI39596.1 - 2.2e-05 24.4 2.1 0.053 13.4 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 KPI39596.1 - 0.00016 21.9 0.3 0.65 10.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KPI39596.1 - 0.00019 21.2 2.2 0.74 9.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KPI39596.1 - 0.00035 21.1 5.2 0.39 11.3 0.0 3.5 5 0 0 5 5 3 2 AAA domain AAA_14 PF13173.6 KPI39596.1 - 0.0018 18.3 0.4 7.6 6.6 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KPI39596.1 - 0.0021 18.5 0.1 1.8 9.0 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KPI39596.1 - 0.0028 17.6 0.6 0.87 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KPI39596.1 - 0.004 16.9 15.4 0.35 10.5 0.0 4.8 4 1 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 KPI39596.1 - 0.0064 16.9 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KPI39596.1 - 0.0066 16.7 6.1 0.18 12.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KPI39596.1 - 0.011 15.8 0.3 8.3 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KPI39596.1 - 0.012 14.6 2.0 2.5 7.0 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 KPI39596.1 - 0.016 14.8 2.6 5.6 6.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 KPI39596.1 - 0.016 14.5 0.9 5.6 6.2 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 KPI39596.1 - 0.021 14.7 0.1 1.9 8.4 0.1 2.7 2 0 0 2 2 2 0 NTPase MobB PF03205.14 KPI39596.1 - 0.022 14.7 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KPI39596.1 - 0.024 14.2 1.0 2.2 7.8 0.7 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KPI39596.1 - 0.025 14.6 0.0 5.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KPI39596.1 - 0.03 14.5 0.1 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KPI39596.1 - 0.032 14.3 5.6 2.9 7.9 0.0 3.7 4 0 0 4 4 3 0 Dynamin family AAA_7 PF12775.7 KPI39596.1 - 0.074 12.6 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KPI39596.1 - 0.09 12.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MukB PF04310.12 KPI39596.1 - 0.11 12.3 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Rad17 PF03215.15 KPI39596.1 - 0.19 11.6 0.9 4.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain ATPase_2 PF01637.18 KPI39596.1 - 2 8.2 5.2 41 4.0 0.0 3.5 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KPI39596.1 - 2.3 8.7 6.0 34 4.9 0.2 3.7 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 KPI39596.1 - 2.5 8.1 10.9 2.9 7.9 0.0 3.9 5 0 0 5 5 4 0 Helicase HerA, central domain Ank_2 PF12796.7 KPI39597.1 - 1.2e-25 89.9 0.0 1.8e-12 47.7 0.0 4.4 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI39597.1 - 1.3e-24 86.2 0.0 7.2e-11 42.4 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI39597.1 - 3.1e-19 68.8 0.0 1.4e-05 25.3 0.0 5.7 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KPI39597.1 - 1.1e-18 66.7 0.0 0.0002 21.6 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KPI39597.1 - 4.9e-17 60.3 0.0 0.17 12.6 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat 2C_adapt PF08793.10 KPI39597.1 - 0.26 11.5 1.5 11 6.2 0.2 2.5 2 0 0 2 2 2 0 2-cysteine adaptor domain Pkinase PF00069.25 KPI39598.1 - 4e-77 259.2 0.0 5.3e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39598.1 - 1.2e-39 136.2 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KPI39598.1 - 4.5e-17 62.1 0.2 9.1e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KPI39598.1 - 3.2e-09 36.5 0.0 5.6e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KPI39598.1 - 1.5e-07 30.5 0.4 3.5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KPI39598.1 - 3.1e-05 24.2 0.0 9.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KPI39598.1 - 0.032 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KPI39598.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.25 KPI39599.1 - 1.9e-32 112.3 0.1 2.5e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39599.1 - 3.4e-21 75.9 0.1 5.7e-21 75.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KPI39599.1 - 6.2e-05 22.5 0.0 0.00097 18.6 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KPI39599.1 - 8.7e-05 22.5 0.0 0.0002 21.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 KPI39599.1 - 0.0025 18.4 0.0 0.0068 17.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KPI39599.1 - 0.0053 16.2 0.0 0.007 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KPI39599.1 - 0.0077 15.9 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KPI39599.1 - 0.015 15.5 0.0 0.078 13.1 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epiglycanin_C PF14654.6 KPI39599.1 - 0.034 14.2 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region ADH_zinc_N PF00107.26 KPI39599.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 KPI39599.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_Gly3P_dh_N PF01210.23 KPI39599.1 - 0.091 12.7 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DFP PF04127.15 KPI39599.1 - 0.096 12.5 0.2 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Amidohydro_3 PF07969.11 KPI39600.1 - 7.2e-52 177.4 1.5 8.2e-52 177.2 1.5 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPI39600.1 - 2.8e-11 43.3 3.5 1e-09 38.2 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Sugar_tr PF00083.24 KPI39601.1 - 6.6e-70 236.2 18.4 7.6e-70 236.0 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39601.1 - 4.8e-22 78.4 44.7 7.8e-19 67.8 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5317 PF17248.2 KPI39601.1 - 8 6.5 9.1 0.26 11.3 2.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5317) Iso_dh PF00180.20 KPI39603.1 - 3.2e-82 276.5 0.0 3.8e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Copine PF07002.16 KPI39603.1 - 0.053 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Copine Bestrophin PF01062.21 KPI39604.1 - 2.6e-33 115.7 0.1 3.8e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MIS13 PF08202.11 KPI39605.1 - 1.6e-54 185.2 2.3 2.8e-54 184.4 2.3 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FAM92 PF06730.11 KPI39605.1 - 0.015 14.8 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 FAM92 protein DUF2408 PF10303.9 KPI39605.1 - 0.018 15.6 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DivIC PF04977.15 KPI39605.1 - 0.062 13.1 0.6 0.17 11.7 0.6 1.7 1 0 0 1 1 1 0 Septum formation initiator CorA PF01544.18 KPI39605.1 - 0.23 10.8 1.0 0.41 9.9 1.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 KPI39605.1 - 0.58 10.6 7.9 3.6 8.1 2.1 3.6 3 1 0 3 3 3 0 Cell division protein ZapB DUF4200 PF13863.6 KPI39605.1 - 1.9 8.9 5.4 0.25 11.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PS_Dcarbxylase PF02666.15 KPI39606.1 - 1.9e-56 190.8 0.0 2.9e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KPI39606.1 - 4.2e-37 126.6 0.0 2.1e-17 63.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain HMG_box PF00505.19 KPI39607.1 - 3e-16 59.6 0.6 6.9e-16 58.4 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPI39607.1 - 5.1e-11 43.0 1.0 9.5e-11 42.1 1.0 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KPI39607.1 - 2.1e-09 37.7 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KPI39607.1 - 2.7e-05 24.2 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KPI39607.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 IGR protein motif BTB PF00651.31 KPI39608.1 - 5.5e-12 45.9 0.1 1.8e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain KASH_CCD PF14662.6 KPI39608.1 - 4.1e-05 23.5 0.5 7.3e-05 22.7 0.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KPI39608.1 - 0.0099 15.6 0.5 0.093 12.5 0.2 2.4 2 0 0 2 2 2 1 Septum formation initiator TMF_DNA_bd PF12329.8 KPI39608.1 - 0.092 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Hydrophobin_2 PF06766.11 KPI39611.1 - 6.3e-24 83.7 11.3 9.5e-24 83.1 11.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Tryp_inh PF17983.1 KPI39611.1 - 8.1 6.6 11.6 1.3 9.2 1.2 2.5 3 0 0 3 3 3 0 Trypsin inhibitors 1,2 and 3 FAD_binding_4 PF01565.23 KPI39612.1 - 2.6e-28 98.5 0.0 4.2e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KPI39612.1 - 9.4e-09 35.3 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.18 KPI39612.1 - 0.001 18.2 0.1 0.0023 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ribosomal_S26e PF01283.19 KPI39613.1 - 6.4e-52 174.5 7.4 7.6e-52 174.3 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KPI39613.1 - 0.022 14.7 0.5 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KPI39613.1 - 0.073 12.9 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Clathrin PF00637.20 KPI39614.1 - 9e-187 612.4 23.9 2.9e-31 108.3 1.8 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KPI39614.1 - 4.4e-32 109.8 1.4 2.9e-31 107.2 0.7 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 KPI39614.1 - 3.5e-28 96.5 0.5 1e-05 25.6 0.0 6.2 6 0 0 6 6 6 5 Clathrin propeller repeat Coatomer_WDAD PF04053.14 KPI39614.1 - 0.0014 17.8 5.5 1.6 7.7 0.0 4.2 4 0 0 4 4 4 2 Coatomer WD associated region VapB_antitoxin PF09957.9 KPI39614.1 - 0.057 13.3 0.1 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Lipase_C PF18067.1 KPI39614.1 - 0.13 12.8 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 Lipase C-terminal domain TPR_7 PF13176.6 KPI39614.1 - 0.2 11.7 5.7 77 3.7 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI39614.1 - 7.5 7.7 19.1 14 6.8 0.1 8.4 9 1 1 10 10 10 0 Tetratricopeptide repeat Raffinose_syn PF05691.12 KPI39617.1 - 7.1e-42 143.1 0.0 4.7e-40 137.1 0.2 2.7 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 DUF2964 PF11177.8 KPI39618.1 - 7 6.9 9.9 5.8 7.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) ISN1 PF06437.11 KPI39620.1 - 1e-178 594.5 0.0 1.1e-178 594.3 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase AAA_assoc_2 PF16193.5 KPI39620.1 - 0.08 13.3 0.1 0.35 11.2 0.2 2.0 2 0 0 2 2 2 0 AAA C-terminal domain TPP_enzyme_N PF02776.18 KPI39622.1 - 1.3e-43 148.6 0.1 5.2e-43 146.6 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPI39622.1 - 1e-38 132.5 0.1 3.7e-38 130.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI39622.1 - 5.6e-20 71.5 0.0 1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain B12-binding PF02310.19 KPI39622.1 - 0.011 15.8 0.0 0.05 13.7 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain AA_permease PF00324.21 KPI39623.1 - 1.1e-143 479.3 37.9 1.3e-143 479.1 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI39623.1 - 1.4e-33 116.3 37.0 1.8e-33 116.0 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease EbsA PF17255.2 KPI39623.1 - 1.5 9.2 4.6 3.6 7.9 4.6 1.6 1 0 0 1 1 1 0 EbsA-like protein DASH_Duo1 PF08651.10 KPI39624.1 - 0.00035 20.3 1.7 0.0097 15.7 0.1 2.9 2 0 0 2 2 2 1 DASH complex subunit Duo1 TSC22 PF01166.18 KPI39624.1 - 1.9 8.8 5.1 5.6 7.4 0.0 3.3 3 1 0 3 3 3 0 TSC-22/dip/bun family Syntaxin_2 PF14523.6 KPI39624.1 - 2.3 8.6 7.1 0.17 12.2 0.3 2.5 3 0 0 3 3 3 0 Syntaxin-like protein RSS_P20 PF11757.8 KPI39624.1 - 7.2 7.1 7.7 22 5.6 7.7 1.9 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain RBD-FIP PF09457.10 KPI39624.1 - 7.3 6.6 7.8 2.4 8.1 0.1 3.6 3 1 0 3 3 3 0 FIP domain Abhydrolase_1 PF00561.20 KPI39625.1 - 6.7e-17 62.0 0.1 3.9e-16 59.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI39625.1 - 1.4e-10 40.9 0.0 9.7e-10 38.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI39625.1 - 1.2e-07 32.6 0.7 1.8e-07 32.0 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KPI39625.1 - 0.0071 16.1 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_2 PF03446.15 KPI39626.1 - 1.9e-28 99.6 3.1 4.8e-28 98.3 3.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI39626.1 - 1.5e-21 76.9 0.0 2.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KPI39626.1 - 8.4e-06 24.9 0.0 0.00046 19.2 0.0 2.1 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KPI39626.1 - 0.0079 16.8 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KPI39626.1 - 0.016 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PIP5K PF01504.18 KPI39627.1 - 1.3e-44 152.5 0.0 1.9e-44 151.9 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DsbC_N PF10411.9 KPI39627.1 - 0.21 11.1 0.4 18 4.9 0.1 2.3 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus NAD_binding_5 PF07994.12 KPI39628.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Spc7_N PF15402.6 KPI39629.1 - 3.9e-242 806.5 67.8 3.9e-242 806.5 67.8 2.3 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KPI39629.1 - 3.8e-102 341.3 13.8 3.8e-102 341.3 13.8 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KPI39629.1 - 4e-06 26.8 0.0 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Spc7_C2 Peptidase_M1 PF01433.20 KPI39630.1 - 3.2e-85 285.1 0.2 5.5e-85 284.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KPI39630.1 - 4.9e-83 279.3 0.1 4.9e-83 279.3 0.1 1.9 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KPI39630.1 - 7.1e-51 173.0 0.4 1.1e-50 172.4 0.4 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain SLAC1 PF03595.17 KPI39631.1 - 1.3e-64 218.6 47.7 1.7e-64 218.1 47.7 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel HET PF06985.11 KPI39631.1 - 1.3e-30 106.7 0.0 2.2e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SulA PF03846.14 KPI39631.1 - 0.05 13.5 0.1 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Cell division inhibitor SulA Ribosomal_S5 PF00333.20 KPI39632.1 - 3.7e-27 94.1 2.7 1.1e-26 92.6 0.7 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KPI39632.1 - 2.5e-22 78.1 0.0 4.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Potassium_chann PF11404.8 KPI39632.1 - 0.55 10.1 2.2 1.1 9.1 2.2 1.5 1 0 0 1 1 1 0 Potassium voltage-gated channel Methyltransf_11 PF08241.12 KPI39634.1 - 7e-17 61.9 0.0 1.4e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI39634.1 - 5.3e-16 59.1 0.0 1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39634.1 - 1.9e-10 41.4 0.0 3.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39634.1 - 7.2e-10 38.9 0.0 2e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI39634.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KPI39634.1 - 3.6e-07 29.5 0.0 5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KPI39634.1 - 3.8e-07 30.1 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI39634.1 - 3.3e-05 23.5 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KPI39634.1 - 3.7e-05 23.0 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase FtsJ PF01728.19 KPI39634.1 - 0.00034 20.8 0.0 0.00048 20.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.11 KPI39634.1 - 0.00039 20.1 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 KPI39634.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 KPI39634.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain BTB PF00651.31 KPI39635.1 - 3.8e-08 33.5 0.0 0.00031 20.9 0.0 3.6 3 1 0 3 3 3 2 BTB/POZ domain DUF3342 PF11822.8 KPI39635.1 - 0.038 14.2 0.0 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) Peptidase_M3 PF01432.20 KPI39635.1 - 0.44 9.7 3.0 0.95 8.6 3.0 1.5 1 0 0 1 1 1 0 Peptidase family M3 IF-2B PF01008.17 KPI39636.1 - 2.5e-77 259.9 0.7 3e-77 259.6 0.7 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2434 PF10361.9 KPI39636.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Med13_N PF11597.8 KPI39636.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Spt5-NGN PF03439.13 KPI39637.1 - 5.3e-24 83.9 0.0 9.4e-24 83.1 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KPI39637.1 - 2.1e-17 63.9 11.2 2.1e-17 63.9 11.2 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KPI39637.1 - 8.3e-10 39.1 25.0 8.3e-10 39.1 25.0 5.0 1 1 2 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KPI39637.1 - 2.4e-08 33.6 10.5 0.0064 16.4 0.2 5.4 5 0 0 5 5 5 4 KOW motif DUF3912 PF13051.6 KPI39637.1 - 0.048 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) LSM PF01423.22 KPI39638.1 - 3e-20 71.7 0.0 3.4e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPI39638.1 - 0.00054 20.1 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KPI39638.1 - 0.0071 16.4 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KPI39638.1 - 0.096 12.3 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Hfq protein Mannosyl_trans PF05007.13 KPI39639.1 - 4.5e-77 259.4 11.5 6.3e-77 258.9 11.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KPI39639.1 - 1e-08 34.7 23.1 6e-08 32.1 21.9 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KPI39639.1 - 0.00049 19.9 24.0 0.00049 19.9 24.0 2.8 1 1 1 2 2 2 1 Glycosyltransferase family 87 TraQ PF09679.10 KPI39639.1 - 7.5 6.6 7.4 24 4.9 0.8 3.6 4 0 0 4 4 4 0 Type-F conjugative transfer system pilin chaperone (TraQ) 2OG-FeII_Oxy_2 PF13532.6 KPI39640.1 - 6.1e-16 59.2 0.0 7.4e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.21 KPI39641.1 - 5.1e-14 52.3 0.0 8.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI39641.1 - 3.4e-12 45.9 0.0 5.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPI39641.1 - 2.4e-09 37.0 0.0 3.8e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KPI39641.1 - 2.6e-07 30.1 0.0 3.4e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KPI39641.1 - 2.9e-06 27.3 0.0 6.1e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPI39641.1 - 0.0012 18.4 0.1 0.0046 16.5 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KPI39641.1 - 0.0038 16.4 0.0 0.0084 15.3 0.0 1.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KPI39641.1 - 0.018 14.5 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Glyco_hydro_16 PF00722.21 KPI39642.1 - 1.9e-17 63.3 0.3 3.3e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KPI39643.1 - 3.7e-16 59.0 36.8 4.5e-13 48.8 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI39643.1 - 0.007 15.3 27.3 7.2 5.4 27.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Med8 PF10232.9 KPI39644.1 - 4.4e-18 65.7 0.0 8e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YL1 PF05764.13 KPI39644.1 - 0.051 13.7 8.1 0.074 13.2 8.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PriC PF07445.12 KPI39644.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC DNA_pol_phi PF04931.13 KPI39644.1 - 0.087 10.9 5.6 0.12 10.4 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KPI39644.1 - 1.2 7.6 3.7 2 6.8 3.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 KPI39644.1 - 1.9 7.7 8.1 2.7 7.2 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KPI39644.1 - 2.4 8.6 7.4 5 7.6 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pes-10 PF07149.11 KPI39644.1 - 6.9 5.6 6.0 9.7 5.1 6.0 1.1 1 0 0 1 1 1 0 Pes-10 PSRP-3_Ycf65 PF04839.13 KPI39645.1 - 0.038 14.2 0.5 0.038 14.2 0.5 1.9 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) DUF641 PF04859.12 KPI39645.1 - 0.14 12.5 5.5 0.11 12.8 3.6 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 KPI39645.1 - 0.17 12.0 6.7 0.21 11.6 6.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KPI39645.1 - 0.18 12.1 6.4 0.28 11.5 6.4 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran PF00005.27 KPI39646.1 - 5.2e-47 159.8 0.0 2.2e-25 89.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI39646.1 - 1.4e-13 50.8 0.1 0.00065 19.2 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPI39646.1 - 2.5e-13 50.5 4.4 0.0014 18.5 1.1 4.6 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPI39646.1 - 2.6e-07 31.4 2.3 0.0033 17.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KPI39646.1 - 5.5e-07 29.7 0.1 0.0029 17.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI39646.1 - 1.3e-06 28.5 0.1 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KPI39646.1 - 1.3e-06 28.0 0.4 0.0061 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 KPI39646.1 - 2.5e-06 27.3 0.3 5.1e-06 26.3 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 KPI39646.1 - 6.9e-06 26.0 0.3 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KPI39646.1 - 3.6e-05 24.1 0.0 0.0057 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPI39646.1 - 0.00012 22.1 0.5 0.082 12.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KPI39646.1 - 0.00025 21.3 0.5 0.79 10.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KPI39646.1 - 0.00088 19.4 0.3 0.12 12.5 0.2 3.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 KPI39646.1 - 0.001 19.7 0.1 0.58 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KPI39646.1 - 0.0011 19.3 0.1 0.65 10.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KPI39646.1 - 0.0017 18.4 0.0 0.8 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KPI39646.1 - 0.0025 17.0 0.2 0.5 9.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain MeaB PF03308.16 KPI39646.1 - 0.0034 16.4 0.4 0.3 10.0 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KPI39646.1 - 0.0066 16.9 0.1 0.78 10.2 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KPI39646.1 - 0.0071 16.1 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KPI39646.1 - 0.0075 16.4 0.0 6 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KPI39646.1 - 0.0084 13.7 0.2 0.24 8.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_16 PF13191.6 KPI39646.1 - 0.0091 16.4 0.0 3.4 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KPI39646.1 - 0.01 15.0 0.3 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 KPI39646.1 - 0.025 13.3 0.0 5 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KPI39646.1 - 0.025 14.8 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KPI39646.1 - 0.034 13.9 0.4 1.8 8.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KPI39646.1 - 0.038 14.1 0.1 0.35 10.9 0.0 2.5 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 KPI39646.1 - 0.062 12.6 0.0 6.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.25 KPI39646.1 - 0.071 12.8 0.2 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.18 KPI39646.1 - 0.081 12.6 0.1 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KPI39646.1 - 0.09 12.7 0.6 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea CLASP_N PF12348.8 KPI39646.1 - 0.14 11.7 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 CLASP N terminal RPN6_N PF18055.1 KPI39646.1 - 0.15 12.4 0.2 7.3 7.0 0.0 2.8 3 0 0 3 3 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Adaptin_N PF01602.20 KPI39646.1 - 0.19 10.2 0.1 0.68 8.4 0.3 1.7 2 0 0 2 2 2 0 Adaptin N terminal region HMGL-like PF00682.19 KPI39648.1 - 1.2e-58 198.7 1.0 1.5e-34 119.8 0.1 2.3 1 1 1 2 2 2 2 HMGL-like zf-RING_2 PF13639.6 KPI39649.1 - 3.2e-09 37.0 3.6 9.2e-09 35.5 3.6 1.8 1 1 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KPI39649.1 - 8.4e-05 22.7 4.9 0.00037 20.6 4.9 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KPI39649.1 - 0.00034 20.6 1.3 0.00034 20.6 1.3 1.8 2 0 0 2 2 1 1 RING-type zinc-finger PHD PF00628.29 KPI39649.1 - 0.0033 17.3 4.3 0.0094 15.8 4.3 1.8 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KPI39649.1 - 0.005 16.7 5.4 0.061 13.3 3.4 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 KPI39649.1 - 0.0052 16.7 1.7 0.011 15.7 1.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPI39649.1 - 0.0092 15.8 1.1 0.036 13.9 1.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI39649.1 - 0.025 14.4 2.4 0.025 14.4 2.4 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KPI39649.1 - 0.074 13.1 3.5 0.075 13.1 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KPI39649.1 - 0.1 12.4 3.1 0.21 11.4 3.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KPI39649.1 - 0.72 10.2 10.0 6.1 7.2 10.0 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain YacG PF03884.14 KPI39649.1 - 0.8 9.5 5.8 8.2 6.2 0.2 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG TFIIA PF03153.13 KPI39649.1 - 2 8.3 16.8 2.8 7.8 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 KPI39649.1 - 2.4 8.4 4.6 1.9 8.7 1.1 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cupin_2 PF07883.11 KPI39650.1 - 0.01 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Fungal_trans PF04082.18 KPI39651.1 - 0.022 13.8 0.1 0.038 13.0 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1772 PF08592.11 KPI39652.1 - 7.8e-17 61.9 0.0 1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Methyltransf_23 PF13489.6 KPI39653.1 - 3e-15 56.4 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39653.1 - 4.9e-13 49.2 0.0 1.5e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39653.1 - 4.1e-12 46.7 0.1 6.5e-11 42.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39653.1 - 1.3e-11 44.9 0.0 1.7e-10 41.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI39653.1 - 1.4e-11 44.9 0.1 1.4e-10 41.7 0.0 2.6 3 1 0 3 3 2 1 Methyltransferase domain PCMT PF01135.19 KPI39653.1 - 6.5e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KPI39653.1 - 3.6e-06 26.5 0.0 7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KPI39653.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPI39653.1 - 0.00015 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KPI39653.1 - 0.0002 20.9 0.1 0.0013 18.3 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain Fibrillarin PF01269.17 KPI39653.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin CMAS PF02353.20 KPI39653.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 KPI39653.1 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F GCD14 PF08704.10 KPI39653.1 - 0.0042 16.8 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_2 PF00891.18 KPI39653.1 - 0.042 13.2 0.1 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_9 PF08003.11 KPI39653.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 KPI39653.1 - 0.047 13.1 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TRM13 PF05206.14 KPI39653.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 RrnaAD PF00398.20 KPI39653.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 KPI39653.1 - 0.17 11.5 0.1 0.5 9.9 0.1 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Citrate_synt PF00285.21 KPI39654.1 - 3.8e-63 213.7 0.0 2e-32 112.6 0.0 2.3 2 0 0 2 2 2 2 Citrate synthase, C-terminal domain COesterase PF00135.28 KPI39656.1 - 3.2e-62 211.1 0.0 4e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI39656.1 - 6.8e-10 39.2 0.3 4.3e-09 36.5 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KPI39656.1 - 0.0033 17.1 0.0 0.0092 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Say1_Mug180 PF10340.9 KPI39656.1 - 0.15 10.9 0.0 0.4 9.5 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase Isochorismatase PF00857.20 KPI39657.1 - 4.5e-45 153.9 0.0 5.2e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Alpha-amylase PF00128.24 KPI39658.1 - 5.7e-98 328.6 0.0 8.1e-98 328.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 KPI39658.1 - 0.0034 17.7 0.1 0.0077 16.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 KPI39658.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KPI39658.1 - 0.022 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Ank PF00023.30 KPI39659.1 - 2e-11 43.8 0.9 1.4e-07 31.7 0.6 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KPI39659.1 - 1.7e-10 41.2 0.4 1.7e-05 25.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI39659.1 - 1.6e-09 38.3 0.0 2.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI39659.1 - 9.5e-08 32.2 0.2 9.9e-07 28.9 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI39659.1 - 1.1e-07 31.5 0.1 2e-05 24.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat FAD_binding_3 PF01494.19 KPI39660.1 - 7.6e-43 147.1 0.0 1.3e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI39660.1 - 8.7e-06 25.2 0.1 2.7e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI39660.1 - 2.9e-05 23.8 0.2 0.038 13.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI39660.1 - 6e-05 23.2 0.1 0.00017 21.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPI39660.1 - 0.00032 19.5 1.2 0.002 16.9 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KPI39660.1 - 0.0022 17.1 0.2 0.0047 16.0 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI39660.1 - 0.0039 16.3 0.5 0.042 12.9 0.2 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KPI39660.1 - 0.016 15.8 0.5 4.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI39660.1 - 0.097 11.7 0.1 0.13 11.3 0.1 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KPI39660.1 - 0.12 11.6 0.2 0.22 10.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KPI39660.1 - 0.13 11.4 0.1 0.43 9.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SUR7 PF06687.12 KPI39661.1 - 1.1e-29 103.6 5.7 2.2e-29 102.6 5.7 1.5 1 1 0 1 1 1 1 SUR7/PalI family CDC45 PF02724.14 KPI39662.1 - 0.36 9.1 6.6 0.55 8.5 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein GDPD PF03009.17 KPI39663.1 - 1.7e-15 57.4 0.0 2.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2380 PF09533.10 KPI39663.1 - 0.28 10.8 2.0 0.56 9.8 2.0 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) LIP PF03583.14 KPI39664.1 - 1.1e-70 238.3 0.1 1.3e-70 238.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Cutinase PF01083.22 KPI39664.1 - 0.012 15.6 0.1 0.03 14.3 0.0 1.7 2 0 0 2 2 2 0 Cutinase Abhydrolase_6 PF12697.7 KPI39664.1 - 0.018 15.6 0.5 0.033 14.8 0.5 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 KPI39665.1 - 1.4e-21 77.1 0.0 1.4e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI39665.1 - 1.4e-07 31.6 0.2 3.2e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI39665.1 - 5e-05 23.0 0.5 0.00018 21.2 0.4 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI39665.1 - 0.00013 21.2 1.6 0.00049 19.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI39665.1 - 0.00028 20.2 0.0 0.0027 17.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KPI39665.1 - 0.0023 17.3 0.1 0.0036 16.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family SE PF08491.10 KPI39665.1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 KPI39665.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KPI39665.1 - 0.047 12.5 0.1 0.068 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KPI39665.1 - 0.065 12.3 0.3 0.093 11.8 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI39665.1 - 0.089 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KPI39665.1 - 0.096 12.3 0.5 0.21 11.1 0.5 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KPI39665.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI39665.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KPI39665.1 - 0.15 10.7 0.1 0.35 9.5 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein mRNA_triPase PF02940.15 KPI39668.1 - 5.1e-48 163.7 0.0 6.8e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain EamA PF00892.20 KPI39669.1 - 3e-13 50.1 24.9 6.1e-08 32.9 2.7 2.4 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 KPI39669.1 - 3.6e-08 32.8 5.3 8.4e-08 31.6 5.3 1.7 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KPI39669.1 - 0.0052 16.0 3.0 0.0097 15.1 0.0 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF202 PF02656.15 KPI39669.1 - 0.11 13.0 11.3 0.36 11.3 3.6 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF202) DUF4579 PF15158.6 KPI39669.1 - 6.2 6.5 7.4 4 7.2 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) F-box-like PF12937.7 KPI39670.1 - 1e-06 28.5 0.1 1.4e-05 24.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 KPI39670.1 - 0.16 12.1 2.3 0.31 11.2 0.5 2.6 2 0 0 2 2 2 0 Leucine Rich repeat RPN2_C PF18004.1 KPI39671.1 - 6.3e-53 179.0 10.0 1.1e-52 178.1 10.0 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KPI39671.1 - 6.2e-32 108.4 25.3 7.2e-10 38.8 0.0 8.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KPI39671.1 - 6.3e-19 68.2 0.2 4.7e-14 52.6 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KPI39671.1 - 1.5e-06 28.0 0.2 0.62 10.5 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KPI39671.1 - 1.5e-06 28.5 3.8 4.5e-05 23.8 0.1 4.7 5 1 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 KPI39671.1 - 0.0015 18.6 0.4 0.042 13.9 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KPI39671.1 - 0.022 15.4 0.9 1 10.2 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat PHD20L1_u1 PF16660.5 KPI39671.1 - 0.034 14.9 5.3 0.29 11.9 2.4 2.6 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 Sec62 PF03839.16 KPI39671.1 - 4.7 6.7 5.1 8.3 5.8 5.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DEP PF00610.21 KPI39672.1 - 0.0099 15.9 0.0 0.051 13.6 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mpv17_PMP22 PF04117.12 KPI39673.1 - 1.7e-23 82.6 0.2 3.2e-23 81.7 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family adh_short_C2 PF13561.6 KPI39674.1 - 3.9e-52 177.1 1.1 4.7e-52 176.9 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI39674.1 - 9.2e-48 162.3 0.5 1.1e-47 162.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI39674.1 - 7.1e-14 52.1 1.1 9.9e-14 51.6 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI39674.1 - 2.2e-05 24.1 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI39674.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NIBRIN_BRCT_II PF16508.5 KPI39675.1 - 7.3e-28 97.3 0.1 5.2e-27 94.5 0.0 2.5 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KPI39675.1 - 1.6e-06 28.4 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KPI39675.1 - 0.0014 18.5 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain DUF3543 PF12063.8 KPI39676.1 - 7.1e-88 294.2 0.2 1.2e-87 293.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KPI39676.1 - 7.8e-59 199.2 0.0 1.4e-58 198.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI39676.1 - 2.5e-42 144.9 0.0 4.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI39676.1 - 0.025 14.5 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI39676.1 - 0.049 13.0 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DEAD PF00270.29 KPI39677.1 - 1.2e-48 165.2 0.0 8.1e-48 162.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI39677.1 - 1.8e-32 112.0 0.0 3.9e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.8 KPI39677.1 - 0.00017 20.5 0.1 0.00029 19.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ResIII PF04851.15 KPI39677.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPI39677.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AMP-binding PF00501.28 KPI39678.1 - 1.1e-51 175.8 0.0 1.4e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPI39678.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.3 3 0 0 3 3 3 0 Acetyl-coenzyme A synthetase N-terminus Rad60-SLD PF11976.8 KPI39680.1 - 6.7e-15 54.7 0.0 3.7e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KPI39680.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family YfmQ PF10787.9 KPI39680.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Fungal_trans PF04082.18 KPI39681.1 - 1e-07 31.3 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ArfGap PF01412.18 KPI39683.1 - 4e-05 23.7 0.8 0.00011 22.3 0.8 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KPI39683.1 - 0.14 12.3 0.9 0.37 11.0 0.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 KPI39683.1 - 1.8 8.3 4.7 2.3 8.0 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Cyt-b5 PF00173.28 KPI39684.1 - 2e-14 53.5 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rib_recp_KP_reg PF05104.12 KPI39684.1 - 1.3 10.1 7.3 2.5 9.1 7.3 1.5 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region PFK PF00365.20 KPI39685.1 - 1.2e-172 572.7 0.1 1.8e-88 296.6 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KPI39685.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Epimerase PF01370.21 KPI39686.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KPI39687.1 - 1.9e-40 138.9 27.3 1.9e-40 138.9 27.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI39687.1 - 6.1e-06 25.3 2.0 6.1e-06 25.3 2.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 KPI39687.1 - 0.019 13.2 0.0 1.9 6.6 0.1 2.1 1 1 1 2 2 2 0 BT1 family DUF2140 PF09911.9 KPI39687.1 - 0.15 11.6 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Abhydrolase_6 PF12697.7 KPI39688.1 - 4.2e-08 34.1 0.0 5.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KPI39688.1 - 0.009 15.7 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase DUF900 PF05990.12 KPI39688.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KPI39688.1 - 0.068 12.9 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf-H2C2_2 PF13465.6 KPI39691.1 - 9e-05 22.7 0.1 9e-05 22.7 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KPI39691.1 - 0.0031 17.9 5.1 0.02 15.3 1.0 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type PyrI_C PF02748.15 KPI39691.1 - 0.02 14.8 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KPI39691.1 - 0.11 13.4 24.3 0.33 11.9 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KPI39691.1 - 1.4 9.3 5.0 8.4 6.8 0.3 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CBS PF00571.28 KPI39692.1 - 1.1e-31 109.1 0.9 2e-09 37.8 0.0 4.4 4 0 0 4 4 4 4 CBS domain DUF2252 PF10009.9 KPI39692.1 - 0.05 12.7 0.9 0.15 11.1 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Baculo_PEP_C PF04513.12 KPI39693.1 - 0.02 15.0 0.3 0.025 14.6 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 KPI39693.1 - 0.045 14.3 3.5 0.054 14.0 3.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_S PF02609.16 KPI39693.1 - 0.055 13.5 0.3 0.091 12.8 0.3 1.3 1 0 0 1 1 1 0 Exonuclease VII small subunit GCN5L1 PF06320.13 KPI39693.1 - 0.08 13.1 0.7 0.1 12.8 0.7 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) YvrJ PF12841.7 KPI39693.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 YvrJ protein family DUF4407 PF14362.6 KPI39693.1 - 0.17 11.2 4.1 0.2 11.0 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-ZPR1 PF03367.13 KPI39693.1 - 0.17 11.7 0.6 0.23 11.3 0.6 1.2 1 1 0 1 1 1 0 ZPR1 zinc-finger domain DASH_Spc19 PF08287.11 KPI39693.1 - 0.18 11.7 3.4 0.19 11.6 3.4 1.1 1 0 0 1 1 1 0 Spc19 Aminotran_1_2 PF00155.21 KPI39694.1 - 1.5e-42 146.1 0.0 1.9e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPI39694.1 - 5.8e-07 28.4 0.0 8.2e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ICL PF00463.21 KPI39695.1 - 7.2e-186 618.7 1.5 8.3e-186 618.5 1.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family p450 PF00067.22 KPI39697.1 - 7.4e-65 219.5 0.0 9.2e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PB1 PF00564.24 KPI39698.1 - 1.9e-10 40.6 0.0 3.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain GMC_oxred_N PF00732.19 KPI39699.1 - 2.2e-64 217.7 0.0 2.8e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI39699.1 - 5.9e-34 117.6 0.0 1e-33 116.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KPI39699.1 - 2.2e-05 24.2 0.5 0.0013 18.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI39699.1 - 0.00023 20.4 1.1 0.012 14.7 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KPI39699.1 - 0.0003 20.0 0.2 0.00046 19.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPI39699.1 - 0.0007 19.8 0.3 0.0023 18.1 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI39699.1 - 0.00099 18.4 0.8 0.028 13.7 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI39699.1 - 0.0032 16.8 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI39699.1 - 0.016 14.5 0.2 0.049 12.9 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KPI39699.1 - 0.061 13.9 0.3 5.4 7.7 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI39699.1 - 0.1 11.3 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein ANAPC4_WD40 PF12894.7 KPI39700.1 - 0.0028 17.9 0.1 4.3 7.7 0.0 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI39700.1 - 0.018 15.9 1.7 0.96 10.4 0.1 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat BiPBP_C PF06832.12 KPI39700.1 - 0.086 12.9 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Fungal_trans PF04082.18 KPI39701.1 - 0.025 13.6 2.7 0.061 12.3 1.2 2.2 2 1 0 2 2 2 0 Fungal specific transcription factor domain SET PF00856.28 KPI39702.1 - 9.8e-16 58.6 0.2 3e-14 53.8 0.0 2.7 2 1 0 2 2 2 1 SET domain NOA36 PF06524.12 KPI39702.1 - 1.2 8.4 9.6 1.7 7.9 9.6 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CSL PF05207.13 KPI39703.1 - 1.9e-15 56.3 0.2 2.7e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KPI39703.1 - 4.5e-12 45.9 0.2 8.1e-12 45.1 0.2 1.4 1 1 0 1 1 1 1 DnaJ domain HRDC PF00570.23 KPI39703.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 HRDC domain DUF3336 PF11815.8 KPI39704.1 - 1.4e-22 79.9 0.9 2.5e-22 79.1 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KPI39704.1 - 1.2e-09 38.7 0.0 3.4e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Ribonuc_L-PSP PF01042.21 KPI39705.1 - 2.6e-08 33.9 0.1 0.00072 19.6 0.0 3.9 3 1 0 3 3 3 2 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 KPI39705.1 - 3.7e-08 33.2 0.0 6.5e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Diphthamide synthase AhpC-TSA_2 PF13911.6 KPI39706.1 - 7e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KPI39706.1 - 3.1e-06 27.1 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI39706.1 - 0.00059 19.6 0.0 0.00089 19.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 KPI39706.1 - 0.085 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Kelch_4 PF13418.6 KPI39707.1 - 6.2e-17 61.4 4.5 6.1e-09 35.7 0.0 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KPI39707.1 - 3.5e-16 59.1 7.5 4.3e-10 39.6 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KPI39707.1 - 3.4e-15 55.7 1.3 2.8e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 KPI39707.1 - 5e-15 54.8 0.1 0.00014 21.4 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KPI39707.1 - 1.9e-12 46.8 3.6 0.00011 22.1 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KPI39707.1 - 2.1e-09 37.0 0.0 7.4e-05 22.6 0.0 4.0 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 KPI39707.1 - 0.00066 19.9 0.0 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain HRXXH PF13933.6 KPI39708.1 - 4.6e-101 337.5 0.1 6e-101 337.1 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family p450 PF00067.22 KPI39709.1 - 1.1e-67 228.8 0.0 1.4e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 KPI39710.1 - 2.9e-79 266.4 0.0 4.9e-79 265.7 0.0 1.3 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SAM_2 PF07647.17 KPI39711.1 - 6.9e-09 35.7 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KPI39711.1 - 3.5e-08 33.7 0.1 7.6e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KPI39711.1 - 2.4e-06 28.0 0.0 5.8e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 PH domain SAM_3 PF18016.1 KPI39711.1 - 0.0061 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ArsA_ATPase PF02374.15 KPI39711.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase HMA PF00403.26 KPI39712.1 - 0.00014 22.2 0.1 0.00029 21.2 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain ACT_6 PF13740.6 KPI39712.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF4142 PF13628.6 KPI39713.1 - 0.047 13.9 0.4 0.047 13.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) HEAT PF02985.22 KPI39713.1 - 0.14 12.5 0.5 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat DUF4410 PF14366.6 KPI39713.1 - 2.1 8.3 4.6 1.7 8.6 1.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4410) R3H PF01424.22 KPI39714.1 - 1.2e-17 63.6 0.2 2.2e-17 62.8 0.2 1.5 1 0 0 1 1 1 1 R3H domain NAD_binding_2 PF03446.15 KPI39715.1 - 1.8e-33 115.9 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI39715.1 - 1.9e-23 83.0 0.0 3.1e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KPI39715.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KPI39715.1 - 0.063 13.9 0.0 0.16 12.6 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1284 PF06935.11 KPI39715.1 - 0.078 13.4 1.1 0.62 10.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1284) Shikimate_DH PF01488.20 KPI39715.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KPI39715.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_FMN PF00724.20 KPI39716.1 - 6.8e-44 150.5 0.0 9.4e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf_CCCH_4 PF18345.1 KPI39717.1 - 2.8e-05 24.0 7.8 2.8e-05 24.0 7.8 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 KPI39717.1 - 3.2e-05 23.6 2.3 5.1e-05 23.0 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KPI39717.1 - 0.00035 20.4 2.4 0.00068 19.5 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-MYND PF01753.18 KPI39717.1 - 0.01 15.9 0.9 0.018 15.1 0.9 1.4 1 0 0 1 1 1 0 MYND finger IF4E PF01652.18 KPI39718.1 - 7.1e-55 185.1 0.9 8.7e-55 184.9 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 KPI39719.1 - 8.8e-22 77.7 0.0 2.9e-10 40.0 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain RPEL PF02755.15 KPI39720.1 - 3.7e-26 90.0 22.2 5.2e-10 38.7 1.4 3.6 4 0 0 4 4 4 3 RPEL repeat CP12 PF02672.15 KPI39720.1 - 0.068 13.9 1.2 7.1 7.5 0.1 2.7 3 0 0 3 3 3 0 CP12 domain UPF0258 PF06789.12 KPI39720.1 - 0.12 12.5 0.9 0.35 11.0 0.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0258) Rotamase_3 PF13616.6 KPI39720.1 - 0.26 11.9 1.5 2 9.0 0.2 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain zf-C2H2_11 PF16622.5 KPI39720.1 - 0.88 9.4 2.3 6.5 6.6 0.1 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Fungal_trans_2 PF11951.8 KPI39721.1 - 5.9e-05 22.0 0.1 0.00015 20.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 KPI39722.1 - 3.9e-13 49.8 0.5 6.1e-13 49.2 0.5 1.3 1 1 0 1 1 1 1 Amidohydrolase AIG2_2 PF13772.6 KPI39723.1 - 3.6e-06 27.3 0.1 9.3e-06 26.0 0.1 1.7 1 1 0 1 1 1 1 AIG2-like family FMO-like PF00743.19 KPI39724.1 - 2.7e-29 102.0 0.0 6.3e-19 67.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI39724.1 - 3.1e-14 52.9 0.0 2e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI39724.1 - 2.2e-10 40.2 0.0 3.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI39724.1 - 2.7e-10 40.4 3.5 6.2e-06 26.0 0.1 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPI39724.1 - 1.7e-09 37.3 0.2 2.8e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI39724.1 - 8.3e-08 32.4 1.5 0.0061 16.6 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI39724.1 - 3.4e-06 27.2 0.1 1.9e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI39724.1 - 1.4e-05 24.6 0.0 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPI39724.1 - 4.8e-05 23.8 1.3 0.082 13.5 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI39724.1 - 0.00012 22.2 0.0 0.017 15.2 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KPI39724.1 - 0.011 15.0 0.2 0.026 13.8 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KPI39724.1 - 0.061 12.0 0.4 1.1 7.9 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 KPI39724.1 - 0.062 12.4 0.1 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KPI39724.1 - 0.082 12.1 0.3 0.46 9.7 0.0 2.2 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.12 KPI39724.1 - 0.11 11.5 1.2 3.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KPI39724.1 - 0.13 12.7 0.0 33 5.0 0.1 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KPI39724.1 - 0.16 11.0 0.1 0.16 11.0 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KPI39724.1 - 0.17 11.2 0.4 0.47 9.7 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase PIN_4 PF13638.6 KPI39725.1 - 0.0029 17.9 0.2 0.012 15.9 0.2 1.9 2 0 0 2 2 2 1 PIN domain Mitoc_mL59 PF18126.1 KPI39726.1 - 6.6e-41 139.6 10.1 5.4e-40 136.7 10.1 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Hamartin PF04388.12 KPI39726.1 - 3.1 6.3 8.5 3.6 6.2 8.5 1.1 1 0 0 1 1 1 0 Hamartin protein Gluconate_2-dh3 PF13618.6 KPI39727.1 - 0.016 15.4 0.5 0.13 12.4 0.4 2.5 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 NAD_binding_3 PF03447.16 KPI39728.1 - 1.5e-07 32.1 0.2 1.3e-06 29.0 0.2 2.4 2 1 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KPI39728.1 - 0.00087 20.1 0.0 0.0022 18.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KPI39728.1 - 0.013 15.7 0.0 0.12 12.4 0.0 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SAF PF08666.12 KPI39728.1 - 0.017 15.7 0.2 0.045 14.4 0.0 1.8 2 0 0 2 2 2 0 SAF domain MPC PF03650.13 KPI39729.1 - 5.5e-35 119.8 0.0 7.4e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Adaptin_N PF01602.20 KPI39730.1 - 7.3e-124 414.2 5.6 8.9e-124 413.9 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KPI39730.1 - 1.7e-30 105.5 0.0 4.4e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KPI39730.1 - 7.5e-14 52.0 0.1 1.5e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KPI39730.1 - 0.00098 19.2 1.9 0.033 14.2 0.0 2.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KPI39730.1 - 0.055 13.7 2.1 0.2 11.8 0.1 3.0 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KPI39730.1 - 0.89 10.0 3.8 2.1 8.8 0.0 3.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain p450 PF00067.22 KPI39733.1 - 3.2e-56 191.0 0.0 4.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SQS_PSY PF00494.19 KPI39734.1 - 1e-35 123.6 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Peroxin-22 PF12827.7 KPI39734.1 - 0.06 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family LSM PF01423.22 KPI39735.1 - 1.8e-10 40.4 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPI39735.1 - 0.00057 20.0 0.0 0.0007 19.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_1 PF07690.16 KPI39736.1 - 9.9e-29 100.3 44.0 2.2e-19 69.6 12.7 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI39736.1 - 1.3e-09 37.1 19.5 4.5e-08 32.0 9.0 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPI39736.1 - 3.9e-07 29.3 7.0 3.9e-07 29.3 7.0 3.0 2 1 2 4 4 4 1 Sugar (and other) transporter AIF-MLS PF14962.6 KPI39736.1 - 0.017 15.1 0.1 0.017 15.1 0.1 2.0 2 0 0 2 2 2 0 Mitochondria Localisation Sequence AgrB PF04647.15 KPI39736.1 - 0.023 14.0 0.7 0.08 12.2 0.7 2.0 1 0 0 1 1 1 0 Accessory gene regulator B Memo PF01875.17 KPI39737.1 - 3.5e-65 219.8 0.0 4.1e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MFS_1 PF07690.16 KPI39738.1 - 6.2e-23 81.3 26.5 8.4e-23 80.9 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI39738.1 - 4e-07 28.9 0.7 7.5e-07 28.0 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.7 KPI39739.1 - 4.1e-10 40.6 1.0 7e-10 39.9 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI39739.1 - 1e-05 25.4 0.1 1.6e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI39739.1 - 0.00013 21.3 0.0 0.00049 19.4 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KPI39739.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_trans_4_5 PF16994.5 KPI39740.1 - 0.022 14.4 0.2 0.057 13.0 0.2 1.7 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Diphthamide_syn PF01866.17 KPI39741.1 - 4.2e-81 272.7 0.0 5.6e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein AAA PF00004.29 KPI39742.1 - 5.3e-14 52.8 0.0 1.3e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI39742.1 - 2.7e-05 24.6 0.3 7.1e-05 23.3 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPI39742.1 - 0.0001 22.6 0.7 0.014 15.7 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KPI39742.1 - 0.0028 17.7 0.0 0.0093 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI39742.1 - 0.01 16.2 1.1 0.02 15.2 0.1 2.0 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 KPI39742.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KPI39742.1 - 0.016 15.4 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPI39742.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 KPI39742.1 - 0.026 14.2 0.0 0.098 12.3 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 KPI39742.1 - 0.035 13.8 0.3 0.061 13.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI39742.1 - 0.044 13.5 0.1 0.14 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KPI39742.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KPI39742.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KPI39742.1 - 0.15 11.9 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Hydin_ADK PF17213.3 KPI39742.1 - 0.15 12.3 0.6 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ABC_tran PF00005.27 KPI39742.1 - 0.18 12.3 0.4 0.6 10.6 0.4 2.1 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 KPI39742.1 - 0.22 11.3 3.1 0.59 9.9 3.1 2.0 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KPI39743.1 - 1.1e-15 57.7 13.4 0.00013 22.7 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39743.1 - 1.7e-07 31.4 0.0 0.033 14.5 0.0 5.0 4 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KPI39743.1 - 0.02 14.8 0.0 17 5.5 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat T4_deiodinase PF00837.17 KPI39743.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase DUF2559 PF10832.8 KPI39744.1 - 0.12 12.5 0.6 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Glyco_hydro_17 PF00332.18 KPI39745.1 - 0.00028 20.6 1.7 0.0014 18.3 0.4 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Fungal_trans PF04082.18 KPI39746.1 - 2.9e-11 42.9 0.2 2.2e-10 40.1 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain PITH PF06201.13 KPI39747.1 - 3.9e-41 140.8 0.7 6e-41 140.2 0.7 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KPI39747.1 - 2.8e-27 94.7 0.0 6.3e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPI39747.1 - 2.5e-06 27.9 0.2 2.6e-05 24.6 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KPI39747.1 - 1.3e-05 25.5 0.0 0.002 18.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KPI39747.1 - 2.2e-05 24.2 0.1 0.025 14.3 0.0 2.4 1 1 1 2 2 2 2 Redoxin OST3_OST6 PF04756.13 KPI39747.1 - 0.00092 18.6 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KPI39747.1 - 0.0017 18.3 0.0 0.056 13.4 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KPI39747.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin AAL_decarboxy PF03306.13 KPI39748.1 - 2.9e-77 258.9 1.8 3.3e-77 258.7 1.8 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase MDM31_MDM32 PF08118.11 KPI39749.1 - 8.3e-240 796.9 0.0 1.1e-239 796.6 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins p450 PF00067.22 KPI39750.1 - 2e-61 208.2 0.0 2.8e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 KPI39751.1 - 1.5e-32 112.9 0.0 2.6e-26 92.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KPI39751.1 - 6.1e-29 101.5 12.1 9.2e-29 100.9 12.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KPI39751.1 - 7.8e-08 32.0 0.9 0.00068 19.1 0.0 4.0 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPI39751.1 - 0.0022 18.3 0.0 0.0052 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ninjurin PF04923.12 KPI39751.1 - 0.011 15.7 0.2 0.031 14.2 0.2 1.8 1 0 0 1 1 1 0 Ninjurin MMR_HSR1 PF01926.23 KPI39751.1 - 0.015 15.4 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 KPI39751.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 KPI39751.1 - 0.054 13.3 0.3 5.6 6.7 0.2 2.6 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KPI39751.1 - 0.078 13.2 0.5 6.1 7.1 0.0 3.5 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KPI39751.1 - 0.16 12.4 0.5 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Amastin PF07344.11 KPI39751.1 - 3 7.7 8.0 0.36 10.7 3.1 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein TPR_14 PF13428.6 KPI39752.1 - 2.4e-07 31.0 7.8 15 6.7 0.4 8.1 6 2 3 9 9 9 3 Tetratricopeptide repeat Suf PF05843.14 KPI39752.1 - 0.00033 20.7 6.6 0.0049 16.9 0.8 3.0 1 1 1 3 3 3 2 Suppressor of forked protein (Suf) Rogdi_lz PF10259.9 KPI39752.1 - 0.043 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein TPR_19 PF14559.6 KPI39752.1 - 0.19 12.2 1.0 67 4.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HAT PF02184.16 KPI39752.1 - 0.31 11.0 20.4 2.9 7.9 0.7 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat Aquarius_N PF16399.5 KPI39753.1 - 1.1e-266 886.9 0.0 1.4e-266 886.6 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KPI39753.1 - 2.2e-26 92.7 0.0 4e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPI39753.1 - 5.6e-23 82.0 0.0 1.5e-22 80.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI39753.1 - 2e-07 31.5 0.0 7.1e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KPI39753.1 - 8.9e-07 29.1 0.0 7.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KPI39753.1 - 2.6e-06 27.3 0.0 0.00016 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI39753.1 - 0.00035 21.0 0.4 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KPI39753.1 - 0.0022 18.4 0.0 0.0066 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KPI39753.1 - 0.0073 15.9 0.1 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SMC_N PF02463.19 KPI39753.1 - 0.0075 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 KPI39753.1 - 0.012 15.6 0.0 0.041 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI39753.1 - 0.021 15.1 0.0 0.1 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KPI39753.1 - 0.048 13.4 0.1 0.85 9.3 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KPI39753.1 - 0.06 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_23 PF13476.6 KPI39753.1 - 0.065 13.7 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KPI39753.1 - 0.078 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DnaB_C PF03796.15 KPI39753.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.16 KPI39753.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Abhydrolase_6 PF12697.7 KPI39754.1 - 0.0019 18.9 1.8 0.0092 16.6 1.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family SGP PF17228.2 KPI39754.1 - 0.047 14.5 0.3 0.11 13.3 0.1 1.7 2 0 0 2 2 2 0 Sulphur globule protein Hydrolase_4 PF12146.8 KPI39754.1 - 0.092 12.0 0.1 28 3.9 0.1 2.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Hemerythrin PF01814.23 KPI39755.1 - 2.2e-07 31.5 1.1 3.3e-07 31.0 1.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Acyl-CoA_dh_1 PF00441.24 KPI39756.1 - 3.5e-39 134.4 0.4 4.8e-39 133.9 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KPI39756.1 - 5e-19 68.2 0.3 1e-18 67.3 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KPI39756.1 - 9.3e-19 68.2 0.0 2.1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI39756.1 - 6.5e-14 51.9 0.1 1.7e-13 50.5 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI39756.1 - 1.4e-06 28.6 0.0 2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ANAPC4_WD40 PF12894.7 KPI39757.1 - 6.6e-07 29.5 0.0 0.0016 18.7 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI39757.1 - 0.04 14.8 7.1 8.7 7.4 0.1 4.8 4 1 0 4 4 4 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KPI39757.1 - 0.085 12.1 0.0 5.6 6.1 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DCR PF14047.6 KPI39757.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region DUF4710 PF15828.5 KPI39757.1 - 0.2 11.8 1.2 0.36 11.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) PBP1_TM PF14812.6 KPI39757.1 - 0.31 11.4 7.4 0.74 10.2 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.11 KPI39757.1 - 0.33 9.7 2.2 0.45 9.3 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 E1-E2_ATPase PF00122.20 KPI39758.1 - 3.2e-44 150.6 4.3 3.2e-44 150.6 4.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KPI39758.1 - 4.4e-06 27.1 0.0 8.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 KPI39758.1 - 0.27 10.0 0.5 0.65 8.7 0.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3382 PF11862.8 KPI39758.1 - 0.29 11.4 5.2 1.7 9.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) BTB PF00651.31 KPI39760.1 - 0.0071 16.6 0.0 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain CobN-Mg_chel PF02514.16 KPI39760.1 - 0.076 10.8 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase DUF1096 PF06493.11 KPI39761.1 - 2.1 8.8 9.7 43 4.7 9.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1096) MFS_1 PF07690.16 KPI39764.1 - 3.5e-35 121.6 28.6 3.5e-35 121.6 28.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily cobW PF02492.19 KPI39765.1 - 9.3e-40 136.1 0.0 1.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KPI39765.1 - 0.00015 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KPI39765.1 - 0.0066 16.7 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KPI39765.1 - 0.0075 16.0 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KPI39765.1 - 0.011 15.4 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KPI39765.1 - 0.019 15.3 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KPI39765.1 - 0.04 14.0 0.0 0.056 13.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KPI39765.1 - 0.055 13.4 0.0 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 KPI39765.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_18 PF13238.6 KPI39765.1 - 0.09 13.3 0.2 0.24 12.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPI39765.1 - 0.092 12.6 0.0 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KPI39765.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI39765.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KPI39766.1 - 1.5e-36 126.1 32.4 2.2e-36 125.5 32.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pap_E4 PF02711.14 KPI39767.1 - 0.0059 17.5 3.3 0.0059 17.5 3.3 2.4 3 0 0 3 3 3 1 E4 protein Activator_LAG-3 PF11498.8 KPI39767.1 - 0.43 9.5 7.7 0.63 9.0 7.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.9 KPI39767.1 - 0.57 9.7 23.9 1.1 8.8 15.6 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fer2_3 PF13085.6 KPI39768.1 - 1.5e-09 37.8 2.3 2.2e-07 30.9 0.0 3.0 3 1 1 4 4 4 2 2Fe-2S iron-sulfur cluster binding domain Zn_clus PF00172.18 KPI39768.1 - 0.0033 17.5 4.5 0.0033 17.5 4.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI39768.1 - 0.031 13.1 0.0 0.074 11.8 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fer4_8 PF13183.6 KPI39768.1 - 0.062 13.8 9.8 0.094 13.2 4.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KPI39768.1 - 0.088 12.9 7.0 0.23 11.6 7.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain ADH_zinc_N PF00107.26 KPI39769.1 - 2.3e-27 95.5 0.2 4.5e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI39769.1 - 2.5e-21 75.6 1.0 5.6e-21 74.5 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KPI39769.1 - 1.4e-07 30.8 0.9 1.8e-07 30.4 0.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI39769.1 - 0.0039 16.1 0.1 0.0054 15.6 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.25 KPI39769.1 - 0.022 14.2 0.2 0.038 13.4 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KPI39769.1 - 0.052 14.6 0.0 0.094 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AbiGi PF10899.8 KPI39769.1 - 0.21 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin Nitroreductase PF00881.24 KPI39771.1 - 2.8e-13 50.3 0.0 4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Amidoligase_2 PF12224.8 KPI39772.1 - 5.3e-14 52.5 5.0 8.3e-07 28.9 1.4 3.0 1 1 0 2 2 2 2 Putative amidoligase enzyme UPF0242 PF06785.11 KPI39772.1 - 0.073 13.2 3.4 0.16 12.0 3.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 KPI39773.1 - 1e-14 54.7 11.8 0.00027 21.7 0.0 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI39773.1 - 1.8e-10 41.0 0.0 0.00018 21.8 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI39773.1 - 0.0018 18.2 0.1 0.021 14.7 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 KPI39773.1 - 0.015 15.1 0.5 0.059 13.2 0.5 2.0 1 0 0 1 1 1 0 HIRA B motif PD40 PF07676.12 KPI39773.1 - 0.02 14.9 6.0 5.3 7.1 0.2 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PSII_BNR PF14870.6 KPI39773.1 - 0.043 13.1 0.0 0.33 10.2 0.1 2.0 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Ge1_WD40 PF16529.5 KPI39773.1 - 0.13 11.2 0.0 7 5.5 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KPI39773.1 - 0.28 10.5 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Sugar_tr PF00083.24 KPI39774.1 - 3.5e-77 260.2 27.3 4.7e-77 259.8 27.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39774.1 - 6.8e-08 31.8 45.8 6.8e-08 31.8 45.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 KPI39775.1 - 8.7e-61 206.1 0.0 1e-60 205.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI39775.1 - 2e-08 34.1 1.0 3.6e-06 26.7 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Aminotran_3 PF00202.21 KPI39776.1 - 5.1e-96 321.8 0.0 2.8e-93 312.8 0.0 2.9 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KPI39776.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KPI39776.1 - 0.07 12.3 0.0 0.2 10.8 0.0 1.8 1 1 1 2 2 2 0 Aminotransferase class I and II Actin PF00022.19 KPI39778.1 - 8.2e-114 380.4 0.0 5.7e-113 377.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KPI39778.1 - 0.018 13.9 0.0 0.16 10.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DnaJ-X PF14308.6 KPI39779.1 - 5.7e-78 261.2 5.2 5.7e-78 261.2 5.2 3.2 3 1 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 KPI39779.1 - 2.8e-24 85.0 0.6 2.8e-24 85.0 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain OrfB_IS605 PF01385.19 KPI39779.1 - 0.023 14.9 1.5 0.023 14.9 1.5 2.0 2 0 0 2 2 2 0 Probable transposase Neur_chan_memb PF02932.16 KPI39779.1 - 1.5 8.8 6.4 1.1 9.2 1.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 KPI39779.1 - 3.2 4.7 5.2 4.5 4.3 5.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PHD PF00628.29 KPI39780.1 - 0.00014 21.7 7.5 0.00027 20.8 7.5 1.4 1 0 0 1 1 1 1 PHD-finger DUF2724 PF10893.8 KPI39780.1 - 0.15 11.9 0.0 0.51 10.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Aminotran_3 PF00202.21 KPI39781.1 - 4e-17 62.0 0.0 5.6e-10 38.4 0.0 3.7 3 1 0 3 3 3 3 Aminotransferase class-III DUF1353 PF07087.11 KPI39781.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Amidase PF01425.21 KPI39782.1 - 8.4e-71 239.2 2.9 3.1e-70 237.4 2.9 1.9 1 1 0 1 1 1 1 Amidase HsbA PF12296.8 KPI39783.1 - 0.018 15.5 4.7 0.038 14.4 0.2 2.9 4 0 0 4 4 4 0 Hydrophobic surface binding protein A Syntaxin_2 PF14523.6 KPI39783.1 - 0.093 13.1 10.7 1.6 9.1 2.8 3.8 3 1 0 3 3 3 0 Syntaxin-like protein DUF465 PF04325.13 KPI39783.1 - 0.11 12.6 2.1 33 4.6 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DUF5320 PF17253.2 KPI39783.1 - 0.26 12.4 0.7 0.85 10.7 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) NPV_P10 PF05531.12 KPI39783.1 - 0.26 11.8 8.8 5.9 7.4 0.9 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KPI39783.1 - 0.8 9.9 13.9 0.22 11.7 1.4 3.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family GAT PF03127.14 KPI39783.1 - 0.97 9.8 3.4 8.8 6.7 0.0 3.7 4 1 0 5 5 5 0 GAT domain Bacillus_HBL PF05791.11 KPI39783.1 - 1.6 8.5 6.8 0.19 11.5 0.4 2.5 2 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AATF-Che1 PF13339.6 KPI39783.1 - 1.7 9.4 6.8 1.3 9.7 1.5 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CxxCxxCC PF03692.15 KPI39784.1 - 0.046 14.4 0.7 0.19 12.4 0.4 2.1 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain Glyco_hydro_88 PF07470.13 KPI39785.1 - 1.7e-83 280.6 1.6 1.9e-83 280.4 1.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prenyltrans PF00432.21 KPI39786.1 - 1.1e-24 85.8 10.6 2.4e-05 24.0 0.5 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KPI39786.1 - 0.1 11.7 0.0 4.6 6.2 0.0 2.5 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain MFS_1 PF07690.16 KPI39787.1 - 3e-34 118.5 29.1 4.3e-34 118.0 29.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KPI39787.1 - 0.0011 17.3 3.9 0.039 12.2 1.8 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.26 KPI39788.1 - 7e-19 68.1 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI39788.1 - 4.3e-15 55.5 0.0 1.2e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI39788.1 - 4.7e-05 23.0 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI39788.1 - 0.027 15.5 0.0 0.05 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-C2H2 PF00096.26 KPI39790.1 - 5.8e-11 42.2 17.0 2.2e-06 27.8 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI39790.1 - 3.6e-08 33.6 9.3 0.003 18.3 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI39790.1 - 1.4e-05 25.2 2.9 0.011 16.0 1.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI39790.1 - 1.7e-05 25.0 2.8 0.0056 17.0 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KPI39790.1 - 0.00012 22.4 5.6 0.00012 22.4 5.6 3.6 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KPI39790.1 - 0.0045 16.9 10.9 0.085 12.9 0.8 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KPI39790.1 - 0.0062 16.2 3.5 1.1 8.9 0.6 2.7 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KPI39790.1 - 0.13 12.2 1.4 14 5.7 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KPI39790.1 - 0.44 10.9 3.5 4.8 7.6 0.6 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KPI39790.1 - 1.2 8.9 8.1 16 5.3 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KPI39790.1 - 3 8.0 6.8 1.4 9.0 2.5 2.3 1 1 1 2 2 2 0 BED zinc finger DUF629 PF04780.12 KPI39790.1 - 3.1 6.2 3.9 14 4.0 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 KPI39790.1 - 6.7 7.3 6.6 36 4.9 1.3 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger XPG_N PF00752.17 KPI39791.1 - 4e-34 117.1 0.0 1.2e-33 115.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KPI39791.1 - 3.9e-26 91.2 0.0 9.8e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KPI39791.1 - 0.0013 19.2 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 KPI39791.1 - 0.0039 17.0 3.3 0.0039 17.0 3.3 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif Beta-lactamase PF00144.24 KPI39792.1 - 3.5e-24 85.7 0.1 5.6e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase SNF2_N PF00176.23 KPI39792.1 - 0.054 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain G-patch PF01585.23 KPI39793.1 - 3.5e-06 26.8 0.2 4.1e-05 23.4 0.2 2.7 1 1 0 1 1 1 1 G-patch domain Utp14 PF04615.13 KPI39793.1 - 0.00067 18.4 23.9 0.00079 18.1 23.9 1.1 1 0 0 1 1 1 1 Utp14 protein G-patch_2 PF12656.7 KPI39793.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.8 3 0 0 3 3 3 0 G-patch domain Rrn6 PF10214.9 KPI39793.1 - 0.51 8.8 23.6 0.79 8.1 23.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4778 PF16008.5 KPI39793.1 - 2.9 7.9 9.5 6 6.8 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Spem1 PF15670.5 KPI39793.1 - 5.1 6.6 12.6 5.3 6.5 11.6 1.5 1 1 0 1 1 1 0 Spermatid maturation protein 1 GREB1 PF15782.5 KPI39793.1 - 5.5 4.0 11.4 7.5 3.5 11.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 KPI39793.1 - 6.6 6.0 10.5 1.5 8.2 7.5 1.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Hydrolase PF00702.26 KPI39795.1 - 2.3e-12 47.6 0.3 3.1e-12 47.2 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPI39795.1 - 0.01 16.3 0.2 0.02 15.3 0.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPI39795.1 - 0.017 14.9 0.2 0.81 9.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 KPI39796.1 - 1.4e-06 27.4 0.1 0.00027 19.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MPTase-PolyVal PF18818.1 KPI39796.1 - 0.091 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Metallopeptidase superfamily domain GlutR_N PF05201.15 KPI39796.1 - 0.15 11.8 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain WD40 PF00400.32 KPI39799.1 - 5e-09 36.6 24.5 0.00069 20.4 0.7 9.7 9 0 0 9 9 9 4 WD domain, G-beta repeat Zip PF02535.22 KPI39800.1 - 1.2e-42 146.4 11.0 1.2e-42 146.4 11.0 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KPI39800.1 - 0.085 12.5 1.0 10 5.9 0.0 3.0 2 1 1 3 3 3 0 Thyroglobulin type-1 repeat GST_C_6 PF17171.4 KPI39801.1 - 0.098 12.5 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 KPI39801.1 - 0.16 12.1 11.6 0.3 11.2 11.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_5 PF07994.12 KPI39802.1 - 6.2e-146 485.9 0.1 8.7e-146 485.4 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KPI39802.1 - 1.9e-45 153.6 0.6 3.8e-45 152.6 0.6 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Glyco_trans_2_3 PF13632.6 KPI39804.1 - 6e-51 173.2 2.2 1.5e-50 171.9 2.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPI39804.1 - 6.9e-05 22.7 0.0 0.00028 20.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPI39804.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KPI39804.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PEMT PF04191.13 KPI39806.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipid methyltransferase DUF1772 PF08592.11 KPI39806.1 - 1.9 8.8 6.8 3.8 7.8 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) zf-ANAPC11 PF12861.7 KPI39807.1 - 9.9e-39 131.3 6.8 1.3e-38 131.0 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KPI39807.1 - 2.8e-19 69.1 10.8 3.9e-19 68.7 10.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KPI39807.1 - 1.5e-06 28.4 16.8 2e-05 24.8 16.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI39807.1 - 0.00092 19.2 10.3 0.0031 17.5 8.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI39807.1 - 0.0027 17.5 6.1 0.0027 17.5 6.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI39807.1 - 0.0048 16.8 11.2 0.014 15.3 11.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.9 KPI39807.1 - 0.006 16.7 4.4 0.008 16.3 0.5 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_4 PF14570.6 KPI39807.1 - 0.023 14.5 13.1 0.028 14.2 2.2 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KPI39807.1 - 0.11 12.4 14.8 0.35 10.7 10.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KPI39807.1 - 0.17 11.8 3.6 0.88 9.5 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-HIT PF04438.16 KPI39807.1 - 0.47 10.4 5.5 0.51 10.2 1.6 2.2 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_17 PF17120.5 KPI39807.1 - 0.93 9.2 11.5 11 5.7 11.5 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KPI39807.1 - 1.1 9.5 15.6 36 4.6 15.6 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 KPI39807.1 - 1.1 9.3 16.0 13 5.8 16.3 2.5 1 1 1 2 2 2 0 zinc-RING finger domain PHD PF00628.29 KPI39807.1 - 1.6 8.7 12.1 5.3 7.0 12.1 1.9 1 1 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 KPI39807.1 - 1.9 8.4 14.1 0.16 11.8 3.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 YacG PF03884.14 KPI39807.1 - 2.8 7.8 9.1 0.65 9.8 0.2 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG RINGv PF12906.7 KPI39807.1 - 3.4 7.9 10.7 12 6.1 10.8 1.9 1 1 0 1 1 1 0 RING-variant domain ESSS PF10183.9 KPI39808.1 - 1.2e-10 41.5 0.0 1.5e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA PF00004.29 KPI39809.1 - 7.4e-43 146.1 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KPI39809.1 - 2.3e-12 46.7 0.2 9.5e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KPI39809.1 - 9.6e-11 41.3 0.1 2.5e-10 40.0 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KPI39809.1 - 2.5e-07 31.3 0.0 0.00013 22.4 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KPI39809.1 - 1.9e-06 27.9 0.0 4.3e-05 23.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPI39809.1 - 2.6e-06 27.7 0.0 8e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KPI39809.1 - 7.8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPI39809.1 - 0.00019 21.7 0.0 0.0031 17.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KPI39809.1 - 0.00046 19.4 0.0 0.0011 18.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KPI39809.1 - 0.00074 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KPI39809.1 - 0.001 19.6 0.0 0.0042 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KPI39809.1 - 0.0017 17.6 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KPI39809.1 - 0.0031 17.7 0.0 0.0095 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KPI39809.1 - 0.0039 16.6 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KPI39809.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 KPI39809.1 - 0.006 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KPI39809.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KPI39809.1 - 0.0085 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KPI39809.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KPI39809.1 - 0.0095 15.6 0.0 0.032 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KPI39809.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KPI39809.1 - 0.033 13.9 0.0 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KPI39809.1 - 0.036 13.4 0.2 0.14 11.5 0.0 2.1 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KPI39809.1 - 0.072 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KPI39809.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KPI39809.1 - 0.092 12.3 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI39809.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KPI39809.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KPI39809.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KPI39809.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 KPI39809.1 - 0.13 12.0 0.2 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KPI39810.1 - 1.6e-24 86.5 60.6 3.6e-18 65.6 45.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KPI39811.1 - 7.8e-11 41.9 0.3 2.3e-10 40.3 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI39811.1 - 7.2e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPI39811.1 - 3.2e-08 33.1 0.0 2e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPI39811.1 - 2.6e-05 23.8 0.3 4.6e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPI39811.1 - 0.0035 16.9 0.2 0.0055 16.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family VanZ PF04892.12 KPI39812.1 - 2.1e-07 31.7 0.5 2.8e-07 31.2 0.5 1.2 1 0 0 1 1 1 1 VanZ like family Asp PF00026.23 KPI39813.1 - 8.9e-79 265.2 5.0 1e-78 264.9 5.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI39813.1 - 6.3e-09 36.3 2.3 0.00027 21.2 1.6 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI39813.1 - 7.3e-06 26.5 0.6 0.022 15.4 0.3 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI39813.1 - 0.004 17.7 0.3 2.6 8.7 0.1 3.1 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Ala_racemase_N PF01168.20 KPI39814.1 - 2.7e-16 59.9 0.1 1e-15 58.0 0.1 1.8 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain MFS_1 PF07690.16 KPI39815.1 - 1.9e-40 138.9 34.2 1.9e-40 138.9 34.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI39815.1 - 2.3e-18 66.3 7.2 2.3e-18 66.3 7.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI39815.1 - 3.7e-08 32.3 2.6 3.7e-08 32.3 2.6 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CPSase_L_D2 PF02786.17 KPI39818.1 - 6.5e-64 215.3 0.9 4.1e-61 206.2 0.9 2.3 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KPI39818.1 - 1.8e-38 131.4 0.0 3.9e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KPI39818.1 - 1.3e-30 105.7 0.0 2.4e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KPI39818.1 - 4.5e-06 26.4 0.0 9.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Dala_Dala_lig_C PF07478.13 KPI39818.1 - 0.008 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KPI39818.1 - 0.13 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Mur_ligase_M PF08245.12 KPI39819.1 - 3.3e-07 30.5 0.1 7.9e-06 26.0 0.1 2.8 1 1 0 1 1 1 1 Mur ligase middle domain TMEM154 PF15102.6 KPI39820.1 - 0.019 14.8 0.1 0.019 14.8 0.1 4.0 2 1 1 3 3 3 0 TMEM154 protein family Apt1 PF10351.9 KPI39820.1 - 0.079 11.8 14.4 0.13 11.1 14.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2207 PF09972.9 KPI39820.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPR3 PF03666.13 KPI39820.1 - 3.1 6.5 10.8 5.6 5.6 10.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 KPI39820.1 - 4.9 5.4 5.4 7.1 4.9 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BUD22 PF09073.10 KPI39820.1 - 6.8 5.9 15.4 12 5.1 15.4 1.4 1 0 0 1 1 1 0 BUD22 FKBP_C PF00254.28 KPI39821.1 - 1.8e-26 92.3 0.0 3.1e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ank_2 PF12796.7 KPI39824.1 - 4.7e-09 36.7 0.1 0.0073 16.9 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI39824.1 - 3.1e-07 30.8 1.6 0.15 12.7 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) NACHT PF05729.12 KPI39824.1 - 3.7e-07 30.2 0.0 9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KPI39824.1 - 5e-07 29.9 4.4 0.058 13.7 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KPI39824.1 - 3.2e-06 27.3 3.3 0.15 12.6 0.1 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KPI39824.1 - 2.2e-05 24.5 0.3 0.17 12.5 0.1 3.8 2 0 0 2 2 2 2 Ankyrin repeat AAA_22 PF13401.6 KPI39824.1 - 0.0076 16.5 0.2 0.051 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI39824.1 - 0.015 15.7 0.1 0.086 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KPI39824.1 - 0.015 15.3 0.0 1.2 9.1 0.0 2.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KPI39824.1 - 0.022 13.9 0.5 0.051 12.8 0.0 1.8 2 1 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KPI39824.1 - 0.072 13.6 0.0 0.28 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KPI39824.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rhabdo_M1 PF03342.13 KPI39824.1 - 0.12 11.7 0.1 3.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) DUF87 PF01935.17 KPI39824.1 - 0.4 10.7 2.3 12 6.0 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KPI39824.1 - 1.2 8.8 3.4 1.6 8.4 0.9 2.4 2 1 0 2 2 2 0 AAA domain RSB_motif PF16294.5 KPI39825.1 - 0.51 10.6 0.0 0.51 10.6 0.0 2.2 3 0 0 3 3 3 0 RNSP1-SAP18 binding (RSB) motif Phage_P2_GpE PF06528.12 KPI39826.1 - 0.017 14.7 0.5 0.017 14.7 0.5 1.7 2 0 0 2 2 2 0 Phage P2 GpE Fungal_trans PF04082.18 KPI39827.1 - 2.9e-06 26.5 0.6 5.5e-06 25.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4106 PF13388.6 KPI39827.1 - 0.55 9.4 2.7 0.84 8.8 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) AAA_8 PF12780.7 KPI39828.1 - 0.013 14.9 0.8 0.03 13.7 0.7 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region D4 Importin_rep_4 PF18808.1 KPI39829.1 - 2.8e-33 114.1 5.4 1.3e-31 108.7 2.1 4.0 2 1 1 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 KPI39829.1 - 6e-22 77.7 6.6 9.7e-09 35.6 0.1 8.1 7 1 1 8 8 6 4 HEAT-like repeat HEAT PF02985.22 KPI39829.1 - 1.5e-20 71.5 7.5 0.0066 16.6 0.0 11.6 12 0 0 12 12 11 4 HEAT repeat Importin_rep_5 PF18816.1 KPI39829.1 - 9.2e-20 70.7 0.1 4e-19 68.7 0.1 2.2 1 0 0 1 1 1 1 Importin repeat HEAT_2 PF13646.6 KPI39829.1 - 2.6e-18 66.2 5.5 0.00025 21.4 0.0 8.3 6 2 2 8 8 8 3 HEAT repeats Importin_rep_6 PF18829.1 KPI39829.1 - 9.2e-12 45.1 2.2 3.3e-11 43.3 0.2 3.0 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KPI39829.1 - 2.5e-10 40.8 0.1 0.036 14.7 0.0 6.3 4 2 2 6 6 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KPI39829.1 - 6.9e-10 38.9 0.2 0.0051 16.4 0.1 6.2 5 2 1 6 6 6 2 CLASP N terminal DUF3385 PF11865.8 KPI39829.1 - 1.2e-09 38.3 0.5 0.016 15.1 0.2 6.7 4 2 0 6 6 6 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KPI39829.1 - 6.4e-09 36.1 1.2 0.015 15.3 0.0 5.2 4 2 0 4 4 3 2 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 KPI39829.1 - 4.2e-07 30.1 2.0 0.0026 17.8 0.0 5.2 4 2 1 6 6 6 1 Exportin 1-like protein Adaptin_N PF01602.20 KPI39829.1 - 1.5e-06 27.1 1.8 0.06 11.9 0.1 4.1 3 1 0 4 4 4 2 Adaptin N terminal region RIX1 PF08167.12 KPI39829.1 - 2.4e-06 27.4 0.6 0.0046 16.7 0.1 4.7 4 1 0 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.23 KPI39829.1 - 7e-06 25.9 7.7 0.31 11.1 0.0 5.7 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KPI39829.1 - 3.2e-05 23.2 9.7 4.1e-05 22.9 0.9 3.6 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DRIM PF07539.12 KPI39829.1 - 0.00013 20.5 5.4 0.018 13.4 0.1 4.0 4 0 0 4 4 4 1 Down-regulated in metastasis RTP1_C1 PF10363.9 KPI39829.1 - 0.00025 21.2 0.9 0.012 15.8 0.2 3.8 4 1 1 5 5 3 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 KPI39829.1 - 0.00033 20.5 1.8 0.02 14.8 0.1 4.3 4 0 0 4 4 3 1 Importin-beta N-terminal domain DNA_alkylation PF08713.11 KPI39829.1 - 0.007 16.1 0.7 0.15 11.8 0.0 3.5 5 0 0 5 5 5 1 DNA alkylation repair enzyme DUF4042 PF13251.6 KPI39829.1 - 0.007 16.1 0.4 11 5.7 0.0 4.4 4 1 0 4 4 3 0 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.14 KPI39829.1 - 0.012 14.9 6.2 0.25 10.6 0.1 3.8 3 1 0 3 3 3 0 V-ATPase subunit H TFCD_C PF12612.8 KPI39829.1 - 0.047 13.5 1.5 2.1 8.2 0.0 3.8 4 1 0 4 4 4 0 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 KPI39829.1 - 0.049 13.9 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF5578 PF17741.1 KPI39829.1 - 0.74 9.2 3.7 1.6 8.1 0.1 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5578) DUF3361 PF11841.8 KPI39829.1 - 1.5 8.8 8.1 12 5.8 0.0 4.8 4 2 2 6 6 5 0 Domain of unknown function (DUF3361) MFS_1 PF07690.16 KPI39830.1 - 5.4e-30 104.5 27.4 9.3e-30 103.7 27.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily HAP PF03866.13 KPI39830.1 - 0.028 14.4 1.4 0.083 12.9 0.3 2.2 1 1 0 2 2 2 0 Hydrophobic abundant protein (HAP) Protocadherin PF08374.11 KPI39830.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Pil1 PF13805.6 KPI39831.1 - 1.6e-126 421.3 0.0 2.1e-126 420.8 0.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KPI39831.1 - 0.043 13.2 2.7 0.046 13.1 1.1 1.8 1 1 1 2 2 2 0 FAM92 protein Atg14 PF10186.9 KPI39831.1 - 0.44 9.6 4.0 6.3 5.8 0.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_S10 PF00450.22 KPI39832.1 - 2.5e-56 191.9 0.0 4.2e-56 191.1 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase OGFr_N PF04664.13 KPI39833.1 - 2.8e-17 62.9 0.0 7.2e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region Kelch_5 PF13854.6 KPI39834.1 - 5.4e-17 61.4 5.9 2.6e-13 49.6 0.2 4.8 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.10 KPI39834.1 - 1.5e-08 33.9 1.0 3.2e-08 32.9 1.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_4 PF13418.6 KPI39834.1 - 5.7e-08 32.6 0.4 0.00018 21.4 0.3 4.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KPI39834.1 - 5.6e-07 29.1 1.7 0.0015 18.1 0.5 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KPI39834.1 - 1.2e-06 28.6 13.1 1.2e-05 25.5 0.7 6.1 6 0 0 6 6 6 1 Galactose oxidase, central domain Amnionless PF14828.6 KPI39834.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Amnionless Kelch_2 PF07646.15 KPI39834.1 - 0.007 16.3 4.7 8.5 6.5 0.3 4.6 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 KPI39834.1 - 0.016 15.5 0.9 0.016 15.5 0.9 3.6 3 1 1 4 4 4 0 Kelch motif SRTM1 PF15872.5 KPI39834.1 - 0.062 13.5 0.4 0.062 13.5 0.4 2.3 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Aldo_ket_red PF00248.21 KPI39835.1 - 3.5e-45 154.4 0.0 4.7e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mis12 PF05859.12 KPI39836.1 - 0.068 13.2 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Mis12 protein Peptidase_M2 PF01401.18 KPI39836.1 - 0.16 10.5 1.4 2.7 6.5 0.1 2.0 2 0 0 2 2 2 0 Angiotensin-converting enzyme LIM PF00412.22 KPI39837.1 - 2.2e-20 72.7 16.3 1.2e-10 41.5 6.8 2.3 2 0 0 2 2 2 2 LIM domain c-SKI_SMAD_bind PF08782.10 KPI39837.1 - 9.4 6.5 13.5 20 5.5 0.8 2.5 1 1 1 2 2 2 0 c-SKI Smad4 binding domain CMD PF02627.20 KPI39838.1 - 1.8e-19 69.6 0.1 2.9e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.6 KPI39838.1 - 0.0025 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 DNA_binding protein, TFX, C-term F-box PF00646.33 KPI39839.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain HET PF06985.11 KPI39840.1 - 2.4e-22 79.9 0.7 9.2e-22 78.0 0.7 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) eIF3_subunit PF08597.10 KPI39841.1 - 2.2e-57 194.7 28.1 2.8e-57 194.4 28.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GREB1 PF15782.5 KPI39841.1 - 3.2 4.7 10.8 3.9 4.5 10.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Aldo_ket_red PF00248.21 KPI39842.1 - 3.1e-55 187.4 0.0 3.5e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LisH PF08513.11 KPI39842.1 - 0.16 12.0 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 LisH Lactamase_B PF00753.27 KPI39844.1 - 1.4e-13 51.3 1.1 2e-13 50.8 1.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI39844.1 - 0.00052 19.6 0.2 0.00078 19.0 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Metallophos PF00149.28 KPI39844.1 - 0.057 13.9 0.3 1.8 9.0 0.1 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase An_peroxidase PF03098.15 KPI39845.1 - 7.3e-34 117.2 0.1 7.8e-27 94.0 0.0 2.6 1 1 1 2 2 2 2 Animal haem peroxidase bZIP_1 PF00170.21 KPI39846.1 - 3.8e-07 30.1 14.7 5e-06 26.5 14.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI39846.1 - 0.00075 19.5 7.3 0.00075 19.5 7.3 1.8 1 1 1 2 2 2 1 Basic region leucine zipper TSC22 PF01166.18 KPI39846.1 - 0.012 15.9 0.3 0.026 14.8 0.3 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family DNA_Packaging_2 PF11123.8 KPI39846.1 - 0.037 14.2 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 DNA packaging protein Atg14 PF10186.9 KPI39846.1 - 0.12 11.5 4.8 0.15 11.2 4.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_Maf PF03131.17 KPI39846.1 - 0.38 11.3 9.4 0.6 10.7 9.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor ZapB PF06005.12 KPI39846.1 - 0.46 11.0 6.0 0.094 13.2 1.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Metallophos PF00149.28 KPI39847.1 - 8.4e-33 114.6 0.2 1.2e-32 114.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPI39847.1 - 1e-15 57.9 0.0 1.8e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Med17 PF10156.9 KPI39848.1 - 2.4e-54 184.8 0.0 3.5e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Folliculin_C PF16692.5 KPI39850.1 - 0.0028 17.4 2.5 0.0036 17.0 2.5 1.1 1 0 0 1 1 1 1 Folliculin C-terminal domain TraH PF06122.11 KPI39850.1 - 0.059 12.6 0.5 0.072 12.4 0.5 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein FAM76 PF16046.5 KPI39850.1 - 0.18 11.1 8.5 0.23 10.8 8.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF1788 PF08747.11 KPI39850.1 - 0.42 10.6 3.1 0.61 10.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) PKcGMP_CC PF16808.5 KPI39850.1 - 0.48 10.3 5.9 3.9 7.4 0.1 3.1 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PCRF PF03462.18 KPI39850.1 - 1.3 8.8 8.5 0.71 9.7 6.1 1.7 1 1 2 3 3 3 0 PCRF domain HEAT PF02985.22 KPI39851.1 - 0.19 12.1 6.4 60 4.3 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat SURF6 PF04935.12 KPI39852.1 - 0.0069 16.2 0.2 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 COG4 PF08318.12 KPI39853.1 - 4.4e-121 404.1 0.0 7.3e-121 403.3 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein Peptidase_M3_N PF08439.10 KPI39853.1 - 0.037 14.3 0.0 0.16 12.2 0.0 2.2 1 1 0 1 1 1 0 Oligopeptidase F SIR2 PF02146.17 KPI39854.1 - 1.6e-56 191.0 0.0 2.2e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family pPIWI_RE_Y PF18156.1 KPI39854.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y Mago-bind PF09282.10 KPI39855.1 - 1.6e-13 50.2 4.5 3.7e-13 49.1 4.5 1.7 1 0 0 1 1 1 1 Mago binding DUF2927 PF11150.8 KPI39855.1 - 0.0065 16.6 0.5 0.0099 16.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2927) Mon1 PF03164.14 KPI39856.1 - 7.6e-133 443.5 0.0 3.8e-92 309.5 0.0 2.1 1 1 1 2 2 2 2 Trafficking protein Mon1 HECT PF00632.25 KPI39857.1 - 4.2e-49 167.7 0.0 2.4e-48 165.2 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Tim17 PF02466.19 KPI39857.1 - 8.5e-30 103.4 7.6 1.7e-29 102.4 7.6 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AZUL PF16558.5 KPI39857.1 - 9.2e-11 41.8 1.5 2.2e-10 40.6 1.5 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A adh_short_C2 PF13561.6 KPI39858.1 - 9.2e-56 189.0 1.4 1.2e-55 188.7 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI39858.1 - 3.6e-44 150.6 1.6 4.7e-44 150.2 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Mucin PF01456.17 KPI39859.1 - 0.073 13.1 2.0 0.15 12.1 2.0 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein GTP_EFTU PF00009.27 KPI39861.1 - 2.6e-47 160.9 0.0 5.2e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KPI39861.1 - 2.5e-21 75.7 3.2 5e-21 74.8 3.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 KPI39861.1 - 3.7e-07 30.2 0.0 1.1e-05 25.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 KPI39861.1 - 0.00046 20.5 0.5 0.23 11.8 0.1 2.8 2 0 0 2 2 2 2 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KPI39861.1 - 0.026 14.9 0.2 0.16 12.4 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu domain 2 Arf PF00025.21 KPI39861.1 - 0.027 13.9 0.0 6 6.3 0.1 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KPI39861.1 - 0.031 14.5 0.1 9.8 6.4 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KPI39861.1 - 0.036 13.5 0.0 2 7.8 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KPI39861.1 - 0.04 13.3 0.0 0.074 12.4 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 KPI39861.1 - 0.094 12.3 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 KPI39861.1 - 0.095 11.8 0.1 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Peptidase_M28 PF04389.17 KPI39862.1 - 8.6e-29 100.6 0.0 2.4e-28 99.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPI39862.1 - 1.2e-07 31.7 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_C25_C PF03785.14 KPI39862.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain fn3 PF00041.21 KPI39862.1 - 0.017 15.5 1.9 0.024 15.0 0.4 1.9 2 0 0 2 2 2 0 Fibronectin type III domain Lipase_3 PF01764.25 KPI39863.1 - 1.1e-17 64.2 0.0 2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KPI39863.1 - 0.0041 17.7 0.1 0.0071 17.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KPI39863.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TFIIIC_sub6 PF10419.9 KPI39866.1 - 1.6e-18 66.4 0.0 2.9e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Rgp1 PF08737.10 KPI39866.1 - 0.009 15.2 0.2 0.015 14.5 0.0 1.3 2 0 0 2 2 2 1 Rgp1 RXT2_N PF08595.11 KPI39866.1 - 2.4 8.2 7.9 1.8 8.6 2.4 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KPI39866.1 - 9.5 5.9 7.6 2.1 8.0 0.3 2.2 2 0 0 2 2 2 0 FAM176 family tRNA-synt_2 PF00152.20 KPI39867.1 - 1.3e-10 40.9 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPI39867.1 - 0.0031 17.5 0.0 0.0079 16.2 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.11 KPI39867.1 - 0.045 13.1 0.1 0.081 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) PPE PF00823.19 KPI39867.1 - 0.046 13.8 0.2 0.091 12.9 0.2 1.5 1 0 0 1 1 1 0 PPE family zf-CHY PF05495.12 KPI39868.1 - 5e-12 46.1 11.4 5e-12 46.1 11.4 4.5 3 1 1 4 4 4 2 CHY zinc finger DEAD PF00270.29 KPI39869.1 - 1.7e-44 151.7 0.0 3.6e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI39869.1 - 6e-28 97.4 0.3 3.1e-27 95.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI39869.1 - 9.1e-08 32.3 0.0 1.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KPI39869.1 - 0.0004 19.3 0.1 0.016 14.0 0.2 2.6 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KPI39869.1 - 1.4 9.2 5.6 0.64 10.3 0.3 2.8 3 1 0 3 3 3 0 AAA domain mRNA_cap_enzyme PF01331.19 KPI39870.1 - 7.7e-54 182.5 0.1 9.9e-54 182.1 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KPI39870.1 - 6.2e-30 104.0 0.0 3.7e-29 101.5 0.0 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KPI39870.1 - 5.7e-09 35.9 0.0 4.4e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KPI39870.1 - 0.0013 19.0 0.1 0.0032 17.8 0.0 1.7 2 0 0 2 2 2 1 RNA ligase Abhydrolase_6 PF12697.7 KPI39871.1 - 1.6e-09 38.7 0.0 2.1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI39871.1 - 2.8e-06 27.2 0.1 6.9e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.12 KPI39871.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus MFS_1 PF07690.16 KPI39872.1 - 1.6e-29 103.0 46.4 1.6e-29 103.0 46.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI39872.1 - 0.0031 16.4 3.3 0.0031 16.4 3.3 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter ELFV_dehydrog PF00208.21 KPI39873.1 - 9.8e-66 221.9 0.0 1.7e-65 221.2 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KPI39873.1 - 8e-16 56.8 0.1 9.7e-11 40.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase DUF4573 PF15140.6 KPI39873.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) ELFV_dehydrog_N PF02812.18 KPI39873.1 - 0.059 13.2 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Methyltransf_25 PF13649.6 KPI39874.1 - 1e-10 42.2 0.0 1.9e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39874.1 - 2.3e-10 41.0 0.0 3.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39874.1 - 1e-08 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI39874.1 - 2.6e-07 30.6 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39874.1 - 5.6e-07 30.2 0.0 8.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI39874.1 - 0.00019 20.8 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPI39874.1 - 0.015 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KPI39874.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 KPI39876.1 - 3.7e-59 200.7 0.0 4.6e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 KPI39877.1 - 7.1e-06 26.8 0.2 7.1e-06 26.8 0.2 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KPI39877.1 - 0.15 10.9 0.0 0.37 9.7 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Ribosomal_L12 PF00542.19 KPI39878.1 - 1.2e-14 54.4 8.6 5.3e-14 52.3 6.5 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KPI39878.1 - 2.3e-11 43.2 12.7 2.3e-11 43.2 12.7 3.0 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DUF2575 PF10837.8 KPI39879.1 - 0.049 13.9 0.1 0.15 12.4 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2575) Solute_trans_a PF03619.16 KPI39880.1 - 4.5e-28 98.5 19.8 5.6e-28 98.2 19.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ATP-grasp PF02222.22 KPI39881.1 - 2.8e-49 167.0 0.0 5.4e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KPI39881.1 - 2.3e-18 65.6 0.0 4.6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KPI39881.1 - 0.0001 21.9 0.0 0.00048 19.7 0.0 1.9 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KPI39881.1 - 0.00082 18.7 1.1 0.0017 17.7 1.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPI39881.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KPI39881.1 - 0.021 15.3 0.0 0.065 13.7 0.1 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 KPI39881.1 - 0.042 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KPI39881.1 - 0.043 13.7 0.5 0.043 13.7 0.5 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_2 PF13639.6 KPI39882.1 - 0.025 14.9 4.3 0.025 14.9 4.3 1.9 2 0 0 2 2 2 0 Ring finger domain Sgf11 PF08209.11 KPI39882.1 - 0.073 12.6 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) EF_assoc_2 PF08356.12 KPI39884.1 - 1.1e-33 115.1 0.0 1.9e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KPI39884.1 - 7.7e-29 99.1 0.5 2e-28 97.8 0.2 1.9 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 KPI39884.1 - 4.9e-25 88.0 0.0 1.2e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KPI39884.1 - 1.9e-11 44.2 0.0 2e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KPI39884.1 - 1.3e-08 34.9 0.0 0.00015 21.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Fungal_trans PF04082.18 KPI39884.1 - 7e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_1 PF00036.32 KPI39884.1 - 6.1e-05 22.3 5.0 0.1 12.2 0.5 3.2 3 0 0 3 3 3 2 EF hand Dynamin_N PF00350.23 KPI39884.1 - 0.00018 21.6 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KPI39884.1 - 0.0036 17.7 0.2 2.2 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain EF-hand_7 PF13499.6 KPI39884.1 - 0.0076 16.7 0.1 1.2 9.6 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.6 KPI39884.1 - 0.0088 16.3 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.6 KPI39884.1 - 0.014 15.2 0.5 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 KPI39884.1 - 0.022 14.7 6.9 0.7 10.0 0.6 3.6 4 0 0 4 4 3 0 EF-hand domain EF-hand_8 PF13833.6 KPI39884.1 - 0.031 14.1 0.5 6.6 6.7 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain pair AIG1 PF04548.16 KPI39884.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_29 PF13555.6 KPI39884.1 - 0.034 13.9 0.2 9.5 6.1 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KPI39884.1 - 0.037 14.5 0.0 1.5 9.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter VirE PF05272.11 KPI39884.1 - 0.045 13.5 0.1 6.5 6.4 0.1 3.0 3 0 0 3 3 3 0 Virulence-associated protein E Arf PF00025.21 KPI39884.1 - 0.055 12.9 0.2 34 3.8 0.0 3.5 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_24 PF13479.6 KPI39884.1 - 0.092 12.5 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain GBP PF02263.19 KPI39884.1 - 0.23 10.7 0.1 0.71 9.1 0.0 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain EF-hand_5 PF13202.6 KPI39884.1 - 1.1 8.9 6.8 6.9 6.3 0.2 3.4 3 0 0 3 3 3 0 EF hand Amidohydro_3 PF07969.11 KPI39885.1 - 2.9e-32 112.8 0.1 4e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPI39885.1 - 4.3e-07 29.6 0.5 0.00027 20.4 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family BTB PF00651.31 KPI39886.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain RRM_1 PF00076.22 KPI39888.1 - 4.2e-26 90.5 0.4 1.5e-09 37.6 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI39888.1 - 0.006 16.4 0.0 0.83 9.6 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif Amino_oxidase PF01593.24 KPI39889.1 - 7.3e-24 84.9 0.1 8.2e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase CDC37_N PF03234.14 KPI39890.1 - 5.7e-47 159.8 2.3 5.7e-47 159.8 2.3 3.8 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KPI39890.1 - 4.6e-41 139.4 1.7 6.7e-41 138.9 0.4 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KPI39890.1 - 5.3e-32 109.9 3.8 5.3e-32 109.9 3.8 2.7 3 0 0 3 3 3 1 Cdc37 C terminal domain ORC4_C PF14629.6 KPI39890.1 - 0.051 12.9 1.0 0.17 11.2 0.2 2.0 1 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus MecA_N PF05223.11 KPI39890.1 - 0.56 10.5 4.9 0.71 10.2 0.4 3.1 2 1 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain MSP7_C PF12948.7 KPI39890.1 - 1.7 9.3 7.0 3.1 8.5 0.2 3.6 4 0 0 4 4 4 0 MSP7-like protein C-terminal domain Bac_luciferase PF00296.20 KPI39891.1 - 1.6e-55 188.8 2.1 2e-55 188.4 2.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase RB_A PF01858.17 KPI39892.1 - 0.89 9.3 4.0 0.32 10.8 1.8 1.3 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain HeLo PF14479.6 KPI39893.1 - 2.7e-20 73.1 0.2 4.2e-17 62.7 0.0 3.0 2 1 0 2 2 2 1 Prion-inhibition and propagation DUF3078 PF11276.8 KPI39893.1 - 0.044 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3078) Ribosomal_L16 PF00252.18 KPI39894.1 - 3e-23 82.3 0.2 7.5e-23 81.0 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 KPI39894.1 - 8.5e-22 76.7 0.0 1.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ldh_2 PF02615.14 KPI39896.1 - 3.9e-117 391.1 0.3 4.6e-117 390.9 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MSC PF09402.10 KPI39897.1 - 5e-100 335.2 0.0 6.6e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KPI39897.1 - 1.6e-15 56.5 0.5 3.6e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 HeH/LEM domain adh_short PF00106.25 KPI39898.1 - 7.8e-52 175.6 1.3 9.2e-52 175.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39898.1 - 7.5e-48 163.1 1.4 1.2e-47 162.5 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39898.1 - 8.4e-11 42.1 0.7 1.3e-10 41.5 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI39898.1 - 0.00044 19.8 0.3 0.0011 18.5 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KPI39898.1 - 0.057 13.6 0.4 0.13 12.4 0.4 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 KPI39899.1 - 1.8e-11 44.3 0.0 3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI39899.1 - 0.00023 20.8 0.1 0.019 14.5 0.0 2.2 1 1 1 2 2 2 2 NmrA-like family Sacchrp_dh_NADP PF03435.18 KPI39899.1 - 0.0078 16.5 0.1 0.049 13.9 0.0 2.3 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KPI39899.1 - 0.021 14.7 0.2 1 9.2 0.0 2.4 2 0 0 2 2 2 0 KR domain DNA_ligase_A_N PF04675.14 KPI39900.1 - 7.3e-43 146.9 0.1 1.5e-42 145.8 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KPI39900.1 - 1.8e-28 99.6 0.0 5e-15 55.7 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KPI39900.1 - 6.4e-27 94.1 0.1 2.7e-26 92.0 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DUF4661 PF15576.6 KPI39900.1 - 0.046 13.6 6.4 0.092 12.6 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Ndc1_Nup PF09531.10 KPI39900.1 - 3.1 6.4 4.0 5.3 5.6 4.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 KPI39900.1 - 3.8 6.0 8.3 7.2 5.0 8.3 1.4 1 0 0 1 1 1 0 Macoilin family zf-HIT PF04438.16 KPI39901.1 - 1.2e-05 25.0 7.4 2.2e-05 24.2 7.4 1.4 1 0 0 1 1 1 1 HIT zinc finger Sugar_tr PF00083.24 KPI39902.1 - 8.8e-122 407.2 19.8 1e-121 407.0 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39902.1 - 2.9e-24 85.6 34.3 6e-22 78.0 17.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily PAP2 PF01569.21 KPI39903.1 - 1e-26 93.3 2.7 1e-26 93.3 1.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily LAT PF15234.6 KPI39903.1 - 0.0034 17.2 3.6 0.0055 16.5 3.6 1.2 1 0 0 1 1 1 1 Linker for activation of T-cells PAP2_3 PF14378.6 KPI39903.1 - 0.057 13.1 6.9 0.07 12.8 5.4 2.0 1 1 0 1 1 1 0 PAP2 superfamily YhhN PF07947.14 KPI39903.1 - 0.74 9.4 5.7 0.19 11.3 0.2 2.3 1 1 1 2 2 2 0 YhhN family Sugar_tr PF00083.24 KPI39904.1 - 2.6e-78 263.9 28.2 3e-78 263.7 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI39904.1 - 5.8e-25 88.0 27.9 9.9e-24 83.9 26.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI39904.1 - 0.41 9.0 15.8 0.052 12.0 6.2 2.7 1 1 2 3 3 3 0 Fungal trichothecene efflux pump (TRI12) MBOAT PF03062.19 KPI39905.1 - 2.4e-47 162.0 15.1 4.1e-47 161.2 15.1 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TrbC PF04956.13 KPI39905.1 - 0.002 18.3 0.2 0.002 18.3 0.2 2.2 2 0 0 2 2 2 1 TrbC/VIRB2 family Spt5_N PF11942.8 KPI39906.1 - 0.032 15.2 0.7 0.032 15.2 0.7 5.4 2 1 3 5 5 5 0 Spt5 transcription elongation factor, acidic N-terminal Apolipoprotein PF01442.18 KPI39907.1 - 1.3e-05 25.2 8.3 0.025 14.5 8.3 2.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Gp-FAR-1 PF05823.12 KPI39907.1 - 0.0009 19.6 5.7 0.11 12.8 0.0 3.7 1 1 2 3 3 3 2 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Prominin PF05478.11 KPI39907.1 - 0.0029 15.7 1.8 0.64 7.9 0.1 2.1 2 0 0 2 2 2 2 Prominin DUF1741 PF08427.10 KPI39907.1 - 0.087 12.5 1.5 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) DUF4795 PF16043.5 KPI39907.1 - 0.32 10.5 9.8 0.1 12.2 0.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF5630 PF18632.1 KPI39907.1 - 0.59 9.4 3.0 4.8 6.4 0.2 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5630) DnaI_N PF07319.11 KPI39907.1 - 0.7 10.6 4.6 0.29 11.9 0.4 2.6 2 1 0 3 3 3 0 Primosomal protein DnaI N-terminus DUF883 PF05957.13 KPI39907.1 - 0.81 10.3 19.8 9.7 6.9 0.0 6.4 3 1 4 7 7 7 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KPI39907.1 - 0.9 9.8 7.2 4.8 7.5 1.7 4.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) GlutR_dimer PF00745.20 KPI39907.1 - 0.99 9.9 5.4 2.1 8.8 0.4 3.4 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain BMFP PF04380.13 KPI39907.1 - 1.7 9.2 9.4 33 5.0 0.2 4.7 3 1 2 5 5 5 0 Membrane fusogenic activity Phage_Gp19 PF09355.10 KPI39907.1 - 2.7 8.4 12.8 0.85 10.1 0.5 3.6 3 1 1 4 4 4 0 Phage protein Gp19/Gp15/Gp42 Glyoxalase PF00903.25 KPI39908.1 - 1.3e-36 125.6 0.1 1.7e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPI39908.1 - 1.1e-14 54.6 0.0 1.8e-05 24.9 0.0 4.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KPI39908.1 - 1.1e-07 32.1 0.0 0.0015 18.7 0.0 3.1 1 1 2 3 3 3 3 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KPI39908.1 - 1.7e-05 24.8 1.5 0.62 10.0 0.1 4.0 4 0 0 4 4 4 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KPI39908.1 - 0.002 18.9 0.0 0.99 10.2 0.0 2.7 2 2 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 KPI39908.1 - 0.063 13.4 0.0 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal HTH_54 PF18607.1 KPI39908.1 - 0.096 12.8 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 ParA helix turn helix domain Aldedh PF00171.22 KPI39909.1 - 1.4e-83 281.0 0.0 1.6e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-UBR PF02207.20 KPI39910.1 - 4.4e-19 68.4 10.4 1.2e-18 67.1 10.4 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KPI39910.1 - 3.5e-06 26.7 1.1 1.8e-05 24.4 0.3 2.5 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Acetyltransf_11 PF13720.6 KPI39910.1 - 0.04 14.4 0.1 0.27 11.7 0.0 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DNA_pol_E_B PF04042.16 KPI39911.1 - 3.2e-49 167.2 0.0 4.6e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B APH PF01636.23 KPI39912.1 - 0.00058 19.9 0.0 0.18 11.7 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family p450 PF00067.22 KPI39914.1 - 3.6e-59 200.7 0.0 5.3e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2791 PF10923.8 KPI39915.1 - 0.023 13.6 0.1 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Vps62 PF06101.11 KPI39916.1 - 2.7e-10 39.2 3.1 2.7e-10 39.2 1.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Amino_oxidase PF01593.24 KPI39917.1 - 7e-25 88.2 0.0 5.3e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI39917.1 - 4e-14 52.6 0.3 1.5e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI39917.1 - 4.8e-07 29.7 0.5 2.2e-06 27.5 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI39917.1 - 0.003 16.8 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KPI39917.1 - 0.0052 16.8 0.0 0.44 10.5 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI39917.1 - 0.0082 15.4 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI39917.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI39917.1 - 0.043 12.9 0.1 0.17 10.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KPI39917.1 - 0.059 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KPI39917.1 - 0.2 10.4 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family ECH_1 PF00378.20 KPI39918.1 - 7.7e-24 84.4 0.0 1e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI39918.1 - 1e-08 35.1 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KPI39922.1 - 1.3e-18 67.1 57.7 3.9e-11 42.5 19.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Asparaginase_2 PF01112.18 KPI39924.1 - 1.8e-60 204.5 0.1 3.5e-29 101.8 0.0 3.1 2 1 1 3 3 3 3 Asparaginase PHY PF00360.20 KPI39925.1 - 2e-29 102.2 0.0 1.5e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.26 KPI39925.1 - 4.2e-19 69.1 0.3 1.3e-18 67.6 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPI39925.1 - 4.5e-12 45.8 1.9 1.1e-11 44.6 0.4 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KPI39925.1 - 1.6e-10 41.1 0.1 6.4e-10 39.2 0.0 2.1 2 1 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 KPI39925.1 - 4.9e-09 36.9 0.0 3.5e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 KPI39925.1 - 5.2e-09 36.7 0.0 1.9e-08 34.9 0.0 2.1 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KPI39925.1 - 0.0017 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec7 PF01369.20 KPI39926.1 - 1.2e-29 103.3 0.1 1.9e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KPI39926.1 - 7.7e-05 23.2 0.6 0.00033 21.1 0.6 2.2 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KPI39926.1 - 0.0015 18.9 0.2 0.0031 17.8 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ANAPC3 PF12895.7 KPI39927.1 - 1.4e-26 92.6 7.0 3.7e-21 75.1 0.5 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KPI39927.1 - 1.6e-25 87.8 1.3 1.9e-05 24.2 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KPI39927.1 - 1.9e-25 86.9 12.4 2.7e-05 24.0 0.0 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI39927.1 - 5.5e-14 51.6 0.0 0.061 13.0 0.0 6.8 5 3 2 7 7 7 5 TPR repeat TPR_12 PF13424.6 KPI39927.1 - 2.9e-13 49.9 5.7 0.021 15.1 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPI39927.1 - 5.7e-13 48.5 11.3 0.054 14.3 0.0 7.8 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KPI39927.1 - 6.9e-13 47.7 0.1 0.0047 17.0 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI39927.1 - 5.7e-10 38.9 0.4 0.83 10.2 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPI39927.1 - 1.9e-08 34.3 2.8 0.017 15.2 0.1 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI39927.1 - 3.5e-08 33.9 14.8 0.01 16.4 0.1 7.7 7 1 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPI39927.1 - 4.2e-08 33.6 11.8 0.0032 17.9 0.0 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KPI39927.1 - 2.9e-06 27.5 7.2 0.52 11.1 0.0 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI39927.1 - 1.9e-05 24.3 3.6 0.59 10.3 0.0 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KPI39927.1 - 6.9e-05 22.2 2.3 0.1 11.8 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat MBOAT_2 PF13813.6 KPI39928.1 - 6.8e-16 58.3 0.6 6.8e-16 58.3 0.6 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1289 PF06945.13 KPI39928.1 - 0.14 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF2929 PF11151.8 KPI39928.1 - 0.44 10.9 0.1 0.44 10.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) p450 PF00067.22 KPI39929.1 - 5.3e-07 28.7 0.0 5.3e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Xpo1 PF08389.12 KPI39929.1 - 0.0048 17.0 0.0 0.0057 16.7 0.0 1.2 1 0 0 1 1 1 1 Exportin 1-like protein KH_1 PF00013.29 KPI39930.1 - 5.3e-42 141.5 3.5 1.6e-17 63.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KPI39930.1 - 5.4e-11 42.2 1.6 0.01 15.6 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KPI39930.1 - 5.5e-05 23.1 0.0 0.024 14.6 0.0 2.6 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 KPI39930.1 - 6.3e-05 23.0 8.0 0.19 11.8 0.2 3.4 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 KPI39930.1 - 6.9e-05 22.6 0.4 0.56 10.1 0.1 3.3 3 0 0 3 3 3 2 KH domain Esterase_phd PF10503.9 KPI39932.1 - 1.9e-08 34.1 0.5 0.0062 16.0 0.1 2.6 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KPI39932.1 - 0.00032 20.2 0.0 0.00096 18.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Rep_fac-A_C PF08646.10 KPI39933.1 - 5.8e-56 188.3 10.1 6.9e-55 184.8 4.7 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KPI39933.1 - 3.2e-37 126.4 0.2 1e-36 124.7 0.1 1.9 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KPI39933.1 - 3.3e-21 75.2 0.2 1.5e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KPI39933.1 - 9.3e-16 57.6 0.2 1.5e-10 40.9 0.0 3.9 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KPI39933.1 - 1.7e-06 27.9 0.1 0.00076 19.3 0.1 3.2 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 KPI39933.1 - 0.0077 16.5 0.0 0.032 14.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF4541 PF15074.6 KPI39933.1 - 0.038 14.6 1.9 0.12 13.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4541) SMAP PF15477.6 KPI39933.1 - 0.08 13.9 0.2 8.8 7.4 0.1 2.8 2 0 0 2 2 2 0 Small acidic protein family Fe-ADH PF00465.19 KPI39934.1 - 4.7e-103 344.8 0.0 5.8e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPI39934.1 - 2.7e-15 56.8 0.0 9.3e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KPI39934.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein ARID PF01388.21 KPI39935.1 - 1e-17 64.5 0.0 3.1e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 KPI39935.1 - 0.061 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Band_7 PF01145.25 KPI39936.1 - 2.1e-20 73.5 4.2 3.6e-20 72.7 4.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family F-box-like PF12937.7 KPI39937.1 - 0.097 12.6 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 F-box-like MFS_1 PF07690.16 KPI39938.1 - 0.00019 20.4 2.9 0.00038 19.5 3.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2157 PF09925.9 KPI39938.1 - 0.021 14.6 0.4 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4516 PF14990.6 KPI39938.1 - 0.27 11.0 4.5 1.3 8.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) Methyltransf_23 PF13489.6 KPI39939.1 - 1.3e-20 73.9 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI39939.1 - 2.6e-10 40.9 0.0 6e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39939.1 - 8.3e-08 32.2 0.0 9.6e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39939.1 - 3.7e-06 27.6 0.0 1.8e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39939.1 - 3.8e-06 27.5 0.0 9.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPI39939.1 - 5.6e-05 23.3 0.0 9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KPI39939.1 - 0.00043 19.9 0.0 0.0015 18.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPI39939.1 - 0.00048 19.6 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 KPI39939.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KPI39939.1 - 0.027 13.8 0.0 0.069 12.4 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KPI39939.1 - 0.11 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KPI39939.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KPI39939.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Patatin PF01734.22 KPI39940.1 - 2.8e-21 76.6 3.4 7.8e-21 75.2 0.6 2.7 2 0 0 2 2 2 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 KPI39940.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KPI39940.1 - 0.043 13.9 1.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family adh_short PF00106.25 KPI39943.1 - 1.1e-17 64.1 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39943.1 - 2.2e-13 50.3 0.2 4.9e-13 49.2 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39943.1 - 8.2e-08 32.4 0.1 1.9e-07 31.2 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KPI39943.1 - 3.1e-05 24.0 0.1 4.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI39943.1 - 0.00065 19.2 0.0 0.00081 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KPI39943.1 - 0.014 15.4 0.4 0.021 14.9 0.4 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KPI39943.1 - 0.038 14.0 0.4 0.062 13.3 0.4 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KPI39943.1 - 0.048 13.8 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_trans_4_4 PF13579.6 KPI39943.1 - 0.071 13.5 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KPI39943.1 - 0.094 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 HET PF06985.11 KPI39944.1 - 1.8e-10 41.3 1.4 7.3e-07 29.6 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.6 KPI39944.1 - 0.026 14.4 0.9 0.067 13.1 0.5 1.8 2 0 0 2 2 2 0 Glycosyl transferase family group 2 DUF294 PF03445.13 KPI39945.1 - 0.02 14.7 0.7 0.073 12.9 0.1 2.2 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 Fez1 PF06818.15 KPI39945.1 - 0.45 10.9 31.0 0.24 11.8 19.0 2.5 2 0 0 2 2 2 0 Fez1 ATG16 PF08614.11 KPI39945.1 - 0.71 10.1 45.4 2.3 8.4 22.3 3.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KPI39945.1 - 1.6 8.2 24.8 0.46 10.0 1.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Surfac_D-trimer PF09006.11 KPI39945.1 - 1.8 8.5 3.8 1.8 8.6 1.1 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF3854 PF12965.7 KPI39945.1 - 1.9 8.5 5.3 0.38 10.7 1.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3854) zf-C3HC PF07967.13 KPI39946.1 - 3.4e-31 108.0 8.0 1.1e-27 96.6 0.0 3.4 3 1 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.10 KPI39946.1 - 1.9e-18 66.4 0.1 3.7e-16 59.0 0.1 2.8 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.21 KPI39946.1 - 0.00088 19.9 2.2 0.65 10.7 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-TFIIB PF13453.6 KPI39946.1 - 0.028 13.7 1.1 0.067 12.5 0.4 2.0 1 1 1 2 2 2 0 Transcription factor zinc-finger ANAPC4_WD40 PF12894.7 KPI39947.1 - 6.5e-07 29.6 0.0 0.55 10.6 0.0 4.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI39947.1 - 6.6e-05 23.6 0.3 6.3 7.8 0.0 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat CFEM PF05730.11 KPI39948.1 - 1.5e-13 50.6 7.3 3.4e-13 49.5 7.3 1.6 1 0 0 1 1 1 1 CFEM domain End_beta_propel PF12217.8 KPI39948.1 - 2.2 6.8 8.3 3 6.4 8.3 1.2 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase PP2C PF00481.21 KPI39949.1 - 5.3e-46 157.3 0.0 1e-45 156.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KPI39949.1 - 1e-39 134.1 60.4 1.1e-11 44.3 2.3 10.9 4 3 8 13 13 13 12 Leucine rich repeat LRR_4 PF12799.7 KPI39949.1 - 2e-37 126.6 62.4 4.3e-06 27.0 2.3 12.3 10 2 3 13 13 13 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KPI39949.1 - 1.6e-25 89.8 0.0 1e-24 87.2 0.0 2.0 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KPI39949.1 - 1.1e-07 31.5 21.9 0.0014 18.1 0.6 5.2 2 2 3 5 5 5 3 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 KPI39949.1 - 5.9e-06 25.9 0.7 2e-05 24.2 0.7 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 KPI39949.1 - 7.8e-05 23.2 0.0 0.00021 21.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_1 PF00560.33 KPI39949.1 - 0.0006 20.0 57.8 0.83 10.4 0.1 15.9 16 2 1 17 17 17 3 Leucine Rich Repeat LRR_5 PF13306.6 KPI39949.1 - 0.075 13.0 9.6 7.5 6.5 0.3 5.0 3 2 1 5 5 5 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KPI39949.1 - 0.51 10.5 55.0 8.1 6.8 0.0 14.4 16 0 0 16 16 16 0 Leucine Rich repeat Aminotran_1_2 PF00155.21 KPI39950.1 - 5.6e-38 131.0 0.0 7.5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPI39950.1 - 0.0071 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Zn_clus PF00172.18 KPI39951.1 - 1.5e-07 31.4 9.7 2.4e-07 30.7 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.11 KPI39952.1 - 1.7e-07 30.9 0.0 3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPI39952.1 - 0.00089 18.9 0.0 0.0038 16.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AA_permease_2 PF13520.6 KPI39953.1 - 2.7e-56 191.2 48.8 3.2e-56 191.0 48.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI39953.1 - 7.4e-15 54.5 44.4 1.3e-14 53.6 44.4 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2678 PF10856.8 KPI39953.1 - 0.49 10.3 9.6 1.3 8.9 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) MFS_1 PF07690.16 KPI39954.1 - 1.6e-39 135.9 40.9 1.6e-39 135.9 40.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RPW8 PF05659.11 KPI39955.1 - 0.014 15.1 0.2 0.014 15.1 0.2 5.0 1 1 2 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.11 KPI39955.1 - 0.021 13.7 99.4 0.23 10.3 23.5 4.9 1 1 4 5 5 5 0 Spc7 kinetochore protein POC1 PF10450.9 KPI39955.1 - 0.16 10.9 0.6 0.29 10.1 0.6 1.3 1 0 0 1 1 1 0 POC1 chaperone Autophagy_N PF03986.13 KPI39956.1 - 8.7e-44 148.8 0.0 2.2e-43 147.5 0.0 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KPI39956.1 - 6.1e-16 57.6 0.6 1e-15 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KPI39956.1 - 1.7e-14 54.1 0.1 3e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Alpha-amylase PF00128.24 KPI39957.1 - 1e-110 370.5 0.1 1.4e-110 370.0 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KPI39957.1 - 4.4e-05 22.8 0.0 7.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain F-box PF00646.33 KPI39958.1 - 0.033 14.1 0.6 0.1 12.5 0.6 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KPI39958.1 - 0.051 13.5 0.5 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 F-box-like Imm40 PF15569.6 KPI39958.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 40 Lectin_leg-like PF03388.13 KPI39959.1 - 5.2e-25 88.1 0.0 7.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family ABC_tran_CTD PF16326.5 KPI39959.1 - 0.0062 16.8 0.4 0.2 11.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 KPI39959.1 - 0.022 14.8 1.2 0.063 13.3 1.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.12 KPI39959.1 - 0.033 13.6 0.2 0.055 12.9 0.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Syntaxin_2 PF14523.6 KPI39959.1 - 0.034 14.5 0.5 0.061 13.7 0.5 1.4 1 0 0 1 1 1 0 Syntaxin-like protein APG17 PF04108.12 KPI39959.1 - 0.18 10.9 0.4 0.26 10.4 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DASH_Hsk3 PF08227.11 KPI39959.1 - 1.1 9.6 3.1 7.2 7.1 0.8 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like adh_short PF00106.25 KPI39960.1 - 2.5e-24 85.8 0.0 4.4e-24 85.0 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39960.1 - 7.7e-18 64.9 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39960.1 - 1.3e-06 28.5 0.1 5.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KPI39960.1 - 0.096 11.8 0.1 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI39960.1 - 0.15 11.5 0.0 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PPR_2 PF13041.6 KPI39961.1 - 3.6e-07 30.3 1.0 4.3 7.6 0.0 6.6 7 0 0 7 7 7 3 PPR repeat family PPR_1 PF12854.7 KPI39961.1 - 0.094 12.4 0.2 1.5 8.6 0.0 3.0 2 0 0 2 2 2 0 PPR repeat PPR_3 PF13812.6 KPI39961.1 - 0.19 11.8 1.1 23 5.2 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_long PF17177.4 KPI39961.1 - 0.56 9.5 8.5 0.21 10.9 2.1 3.2 3 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KPI39961.1 - 1.8 9.0 0.0 1.8 9.0 0.0 5.9 8 0 0 8 8 8 0 PPR repeat MFS_1 PF07690.16 KPI39962.1 - 2.2e-44 151.9 65.3 2.7e-43 148.3 64.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily CENP-F_leu_zip PF10473.9 KPI39964.1 - 0.003 17.6 11.0 0.003 17.6 11.0 7.3 2 2 5 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KPI39964.1 - 0.0066 16.7 22.0 0.0066 16.7 22.0 7.5 1 1 6 7 7 7 4 Autophagy protein 16 (ATG16) GAS PF13851.6 KPI39964.1 - 0.014 14.7 98.4 0.13 11.6 7.4 7.3 1 1 5 7 7 7 0 Growth-arrest specific micro-tubule binding tRNA-synt_2 PF00152.20 KPI39965.1 - 6.3e-76 255.4 0.1 8.3e-76 255.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KPI39965.1 - 3e-12 46.3 0.0 4.9e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KPI39965.1 - 2e-05 24.2 0.3 0.089 12.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Zn_clus PF00172.18 KPI39966.1 - 2.8e-05 24.1 6.7 6e-05 23.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 KPI39967.1 - 6.9e-16 58.5 0.1 1e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI39967.1 - 1e-08 35.1 0.1 1.4e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Ldh_1_N PF00056.23 KPI39967.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AMP-binding PF00501.28 KPI39968.1 - 4.9e-54 183.5 0.0 6.7e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI39968.1 - 2.4e-12 47.6 0.0 2.5e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACOX PF01756.19 KPI39969.1 - 4.3e-39 133.9 0.1 1.1e-38 132.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KPI39969.1 - 4.8e-23 82.1 0.8 4.8e-23 82.1 0.8 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPI39969.1 - 1.8e-09 37.6 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI39969.1 - 0.11 13.1 0.0 0.31 11.7 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Helo_like_N PF17111.5 KPI39970.1 - 0.063 12.6 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins ADH_zinc_N PF00107.26 KPI39971.1 - 6.6e-26 90.8 0.5 1.1e-25 90.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI39971.1 - 5.9e-19 69.4 0.1 1.2e-18 68.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI39971.1 - 1.4e-09 37.8 0.0 2.3e-07 30.7 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KPI39971.1 - 0.0012 19.0 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain TMEM208_SND2 PF05620.11 KPI39974.1 - 3.1e-52 176.7 0.1 3.5e-52 176.6 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DRIM PF07539.12 KPI39975.1 - 3.1e-129 432.1 7.4 3.1e-129 432.1 7.4 3.3 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 KPI39975.1 - 0.00088 19.3 6.1 11 6.6 0.0 7.5 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 KPI39975.1 - 0.025 15.0 17.7 0.89 10.0 0.0 8.7 11 0 0 11 11 11 0 HEAT repeats TAF6_C PF07571.13 KPI39975.1 - 0.39 11.1 2.5 47 4.4 0.0 5.3 6 1 0 6 6 6 0 TAF6 C-terminal HEAT repeat domain Adaptin_N PF01602.20 KPI39975.1 - 4.2 5.8 10.1 7 5.1 0.0 4.7 5 1 0 5 5 5 0 Adaptin N terminal region NUP214 PF16755.5 KPI39976.1 - 5.3e-08 32.5 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KPI39976.1 - 0.079 13.3 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KPI39977.1 - 7.7e-05 23.1 0.0 0.00021 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KPI39977.1 - 0.078 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Zn_clus PF00172.18 KPI39978.1 - 1.5e-08 34.6 9.4 2.1e-08 34.1 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.8 KPI39981.1 - 3.7e-50 170.7 0.1 7.4e-50 169.8 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 KPI39982.1 - 1.2e-23 83.6 1.6 1.5e-23 83.3 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FtsJ PF01728.19 KPI39983.1 - 2.9e-63 213.2 0.0 3.9e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase ketoacyl-synt PF00109.26 KPI39984.1 - 4.9e-54 183.6 2.4 2.8e-53 181.1 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPI39984.1 - 2.1e-35 121.3 0.9 4.2e-35 120.3 0.9 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KPI39984.1 - 1.6e-06 27.7 0.5 0.00014 21.4 0.1 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI39984.1 - 0.00045 19.9 4.4 0.02 14.6 0.7 3.0 2 2 1 3 3 3 2 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KPI39984.1 - 0.0063 16.3 0.4 4.2 7.3 0.0 3.2 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KAsynt_C_assoc PF16197.5 KPI39984.1 - 0.13 12.7 0.0 0.67 10.4 0.0 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Lactamase_B_3 PF13483.6 KPI39985.1 - 6.2e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KPI39985.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Meiotic_rec114 PF03525.14 KPI39986.1 - 0.031 13.3 1.8 0.032 13.2 0.1 1.8 2 0 0 2 2 2 0 Meiotic recombination protein rec114 CSTF2_hinge PF14327.6 KPI39987.1 - 6.2e-30 103.5 6.3 6.2e-30 103.5 6.3 2.6 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KPI39987.1 - 4.3e-22 77.7 0.1 6.4e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KPI39987.1 - 2.4e-13 49.4 7.1 7.6e-13 47.8 7.1 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KPI39987.1 - 0.083 13.0 0.1 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif PseudoU_synth_1 PF01416.20 KPI39988.1 - 3.6e-10 40.3 0.0 1.6e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KPI39988.1 - 0.086 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Lin-8 PF03353.15 KPI39988.1 - 0.41 10.2 9.7 0.015 14.9 3.7 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MFS_1 PF07690.16 KPI39989.1 - 2.9e-34 118.5 27.6 4.4e-34 118.0 27.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI39989.1 - 0.037 12.9 6.1 0.027 13.3 4.5 1.4 1 1 0 1 1 1 0 MFS_1 like family adh_short PF00106.25 KPI39991.1 - 1.1e-30 106.6 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI39991.1 - 1.5e-17 63.9 0.0 2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI39991.1 - 1.8e-05 24.8 0.4 0.0001 22.3 0.4 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI39991.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KPI39991.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KPI39991.1 - 0.055 12.6 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KPI39991.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) GST_N_2 PF13409.6 KPI39992.1 - 1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI39992.1 - 0.00064 20.1 0.0 0.0018 18.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI39992.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI39992.1 - 0.007 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI39992.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SIS PF01380.22 KPI39993.1 - 1.6e-13 50.6 0.2 5.1e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 KPI39993.1 - 0.064 13.3 0.1 1.5 8.8 0.1 2.2 1 1 1 2 2 2 0 SIS domain WGG PF10273.9 KPI39994.1 - 1.2e-19 70.7 0.2 2.1e-19 70.0 0.2 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KPI39994.1 - 0.056 13.6 1.7 0.073 13.2 0.2 1.8 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MFS_1 PF07690.16 KPI39995.1 - 9.1e-16 57.7 44.5 9.1e-16 57.7 44.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_MCEL PF03291.16 KPI39996.1 - 2.9e-56 191.0 0.0 3.6e-41 141.4 0.0 2.6 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KPI39996.1 - 3.7e-10 40.4 0.1 0.00024 21.7 0.0 3.1 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_12 PF08242.12 KPI39996.1 - 1.5e-08 35.3 0.0 5.2e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI39996.1 - 4.6e-07 30.4 0.0 2.8e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI39996.1 - 2.6e-05 24.1 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI39996.1 - 4e-05 23.5 0.0 0.0047 16.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DDRGK PF09756.9 KPI39996.1 - 0.017 14.7 0.1 1.8 8.2 0.0 2.5 3 0 0 3 3 3 0 DDRGK domain NNMT_PNMT_TEMT PF01234.17 KPI39996.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family THRAP3_BCLAF1 PF15440.6 KPI39996.1 - 0.12 11.3 15.9 0.24 10.4 15.9 1.6 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Dopey_N PF04118.14 KPI39998.1 - 1.4e-102 342.9 0.0 3.9e-102 341.5 0.0 1.8 1 0 0 1 1 1 1 Dopey, N-terminal D-ser_dehydrat PF14031.6 KPI39999.1 - 4e-23 81.9 0.0 9.3e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KPI39999.1 - 1.8e-15 57.2 0.0 3.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FAS_I_H PF18314.1 KPI39999.1 - 0.14 11.7 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain Beta-lactamase PF00144.24 KPI40002.1 - 1.1e-31 110.3 0.0 1.9e-31 109.6 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 KPI40004.1 - 1.6e-28 99.6 1.2 2.7e-28 98.9 1.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 KPI40005.1 - 1.4e-22 81.2 0.0 2.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPI40005.1 - 6.2e-11 42.4 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UCR_UQCRX_QCR9 PF05365.12 KPI40006.1 - 8.1e-26 89.7 2.0 9.3e-26 89.5 2.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Glyco_hydro_20 PF00728.22 KPI40007.1 - 1.4e-51 176.0 0.0 2.8e-50 171.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KPI40007.1 - 6.8e-17 62.4 0.0 1.8e-16 61.0 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KPI40007.1 - 0.00015 22.6 0.0 0.00027 21.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 V-set_CD47 PF08204.11 KPI40007.1 - 0.028 14.4 0.4 0.92 9.5 0.2 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HA2 PF04408.23 KPI40008.1 - 5.2e-18 65.3 0.0 1.5e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPI40008.1 - 8.6e-13 48.5 0.1 1.8e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPI40008.1 - 7.5e-10 39.1 0.0 4.2e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KPI40008.1 - 0.001 19.4 0.0 0.0035 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KPI40008.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KPI40008.1 - 0.0076 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KPI40008.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KPI40008.1 - 0.064 12.6 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 KPI40008.1 - 0.094 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Annexin PF00191.20 KPI40009.1 - 1.1e-43 147.1 1.1 4.9e-13 49.0 0.0 4.1 4 0 0 4 4 4 4 Annexin UPF0492 PF15744.5 KPI40010.1 - 0.049 12.8 10.5 0.055 12.7 10.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 SRP-alpha_N PF04086.13 KPI40010.1 - 1 9.2 15.4 1.3 8.9 15.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Neur_chan_memb PF02932.16 KPI40010.1 - 1.4 8.9 6.0 1.9 8.5 6.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 KPI40010.1 - 8 5.0 12.7 8.8 4.9 12.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KPI40010.1 - 9.2 4.9 12.8 11 4.7 12.8 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 KPI40010.1 - 9.4 3.2 9.9 10 3.1 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Vps62 PF06101.11 KPI40011.1 - 4.2e-13 48.5 0.5 1.1e-12 47.1 0.4 1.6 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 MFS_1 PF07690.16 KPI40012.1 - 7.2e-35 120.6 25.5 8.3e-35 120.3 25.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Trep_Strep PF09605.10 KPI40012.1 - 4.6e-05 23.5 6.6 4.6e-05 23.5 6.6 2.1 2 0 0 2 2 2 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2417 PF10329.9 KPI40012.1 - 0.015 14.8 0.1 0.051 13.0 0.1 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) WAC_Acf1_DNA_bd PF10537.9 KPI40013.1 - 7.5e-37 125.9 0.1 4e-36 123.6 0.0 2.4 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KPI40013.1 - 1.4e-21 76.8 0.2 1.4e-21 76.8 0.2 2.9 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KPI40013.1 - 3.2e-17 62.6 2.5 6.2e-17 61.7 2.5 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KPI40013.1 - 0.0037 16.8 0.0 0.093 12.3 0.0 2.7 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 SNO PF01174.19 KPI40014.1 - 3.7e-57 193.2 0.0 7.7e-46 156.3 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KPI40014.1 - 5.3e-10 39.2 0.0 1.2e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KPI40014.1 - 0.00033 20.5 0.0 0.0013 18.6 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KPI40014.1 - 0.0032 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KPI40014.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ThiJ_like PF17124.5 KPI40014.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Cellulase PF00150.18 KPI40015.1 - 2e-06 27.5 0.1 4.7e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPPK_C PF12555.8 KPI40015.1 - 0.018 15.1 0.2 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal adh_short PF00106.25 KPI40016.1 - 1.2e-13 51.0 0.0 4.1e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI40016.1 - 1.3e-07 31.7 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI40016.1 - 8.6e-05 22.2 0.0 0.00019 21.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI40016.1 - 0.073 12.5 0.0 0.09 12.2 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RNase_H2-Ydr279 PF09468.10 KPI40017.1 - 0.044 14.0 1.1 0.051 13.8 1.1 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF883 PF05957.13 KPI40017.1 - 0.072 13.7 0.7 0.084 13.5 0.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3810 PF12725.7 KPI40017.1 - 0.17 11.2 1.0 0.19 11.1 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ago_hook PF10427.9 KPI40018.1 - 0.041 14.4 0.9 0.048 14.2 0.9 1.1 1 0 0 1 1 1 0 Argonaute hook ADH_N PF08240.12 KPI40019.1 - 3e-22 78.6 2.7 4.8e-22 77.9 2.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI40019.1 - 3.3e-14 53.0 0.0 8.1e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI40019.1 - 0.00063 19.1 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPI40019.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 KPI40019.1 - 0.15 11.8 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_clus PF00172.18 KPI40020.1 - 0.029 14.5 2.7 0.05 13.7 2.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF21 PF01595.20 KPI40021.1 - 6e-33 114.0 0.0 9.5e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KPI40021.1 - 4.5e-07 30.2 0.6 0.0056 17.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain COesterase PF00135.28 KPI40022.1 - 1.7e-88 297.8 0.0 2.1e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI40022.1 - 4.5e-05 23.4 0.1 0.00035 20.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Arginase PF00491.21 KPI40023.1 - 1.9e-93 313.0 0.0 2.5e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KPI40023.1 - 0.016 15.5 0.5 0.025 14.8 0.5 1.2 1 0 0 1 1 1 0 UPF0489 domain JmjC PF02373.22 KPI40024.1 - 1.1e-09 38.7 0.1 3.2e-09 37.2 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KPI40024.1 - 6.5e-08 32.6 0.3 1.7e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 Cupin-like domain PHD PF00628.29 KPI40024.1 - 4.6e-07 29.6 6.1 4.6e-07 29.6 6.1 2.5 3 0 0 3 3 3 1 PHD-finger JHD PF17811.1 KPI40024.1 - 0.00021 21.8 0.3 0.00051 20.5 0.3 1.6 1 0 0 1 1 1 1 Jumonji helical domain C1_1 PF00130.22 KPI40024.1 - 0.011 15.6 0.9 0.011 15.6 0.9 2.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KPI40024.1 - 0.11 12.1 2.4 0.35 10.4 2.4 1.9 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KPI40024.1 - 0.4 10.8 5.4 1.3 9.2 5.4 1.9 1 0 0 1 1 1 0 PHD-finger Zn_clus PF00172.18 KPI40024.1 - 0.45 10.7 28.7 0.25 11.5 6.7 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 KPI40027.1 - 2.9e-36 125.8 0.1 6.2e-35 121.4 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KPI40027.1 - 0.0028 16.9 0.2 0.004 16.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI40027.1 - 0.0039 17.4 0.9 0.012 15.8 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI40027.1 - 0.034 13.4 0.3 0.055 12.7 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI40027.1 - 0.038 13.2 0.2 0.062 12.5 0.2 1.2 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KPI40027.1 - 0.044 13.4 0.3 0.089 12.3 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI40027.1 - 0.063 12.4 1.6 0.1 11.6 1.6 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KPI40027.1 - 0.095 11.8 0.4 0.14 11.3 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PXA PF02194.15 KPI40028.1 - 1.8e-35 122.6 0.2 5.7e-35 120.9 0.2 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KPI40028.1 - 1.2e-21 77.4 0.6 9.6e-21 74.5 0.1 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KPI40028.1 - 4.9e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 PX domain CwfJ_C_1 PF04677.15 KPI40029.1 - 2.5e-17 62.9 0.0 4.4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KPI40029.1 - 1.6e-10 41.7 0.4 3.4e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF2433 PF10360.9 KPI40030.1 - 1.7e-36 125.1 0.0 3.6e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KPI40030.1 - 0.00076 20.0 0.0 0.0017 18.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI40030.1 - 0.0046 17.2 0.0 0.021 15.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RPN7 PF10602.9 KPI40032.1 - 2.7e-57 193.3 0.6 4.3e-57 192.6 0.2 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KPI40032.1 - 2.4e-17 63.4 0.0 4.7e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 KPI40032.1 - 0.015 15.3 0.0 0.085 12.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 KPI40033.1 - 2.2e-50 171.8 0.0 1.3e-49 169.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 ScsC_N PF18312.1 KPI40033.1 - 0.15 11.9 0.5 0.29 11.0 0.5 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain zf-CCCH_2 PF14608.6 KPI40034.1 - 4.9e-10 39.5 56.3 0.0015 18.9 11.4 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf_C2H2_6 PF18450.1 KPI40034.1 - 0.0012 18.5 0.2 0.0038 16.9 0.2 1.8 1 0 0 1 1 1 1 Zinc Finger domain Nab2 PF11517.8 KPI40034.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Med14 PF08638.11 KPI40035.1 - 1.2e-51 174.9 0.3 2.3e-51 174.0 0.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 WW PF00397.26 KPI40036.1 - 7.4e-12 45.1 7.1 7.2e-09 35.6 3.9 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 KPI40036.1 - 7e-09 35.7 9.0 4.4e-07 30.0 0.0 3.7 4 0 0 4 4 4 1 FF domain Phage_integr_3 PF16795.5 KPI40036.1 - 0.093 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Archaeal phage integrase VGLL4 PF15245.6 KPI40036.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 AA_permease_2 PF13520.6 KPI40037.1 - 2e-44 152.1 47.1 2.4e-44 151.8 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease GST_N_3 PF13417.6 KPI40038.1 - 4.4e-12 46.2 0.1 7.1e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI40038.1 - 6.6e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI40038.1 - 5.6e-05 23.4 0.0 9.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI40038.1 - 0.0069 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI40038.1 - 0.03 14.4 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI40038.1 - 0.066 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MOSC PF03473.17 KPI40039.1 - 2.5e-30 105.2 0.0 4.1e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KPI40039.1 - 3.7e-21 75.2 0.0 6.2e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Alanine_zipper PF11839.8 KPI40041.1 - 0.26 11.7 10.9 0.62 10.5 10.9 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Trypan_PARP PF05887.11 KPI40041.1 - 0.28 11.2 3.0 0.53 10.3 3.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cupin_2 PF07883.11 KPI40042.1 - 6.7e-17 61.0 0.0 1.2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KPI40042.1 - 2.8e-06 27.3 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KPI40042.1 - 5.5e-05 22.8 0.0 8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KPI40042.1 - 0.00012 22.3 0.1 0.00023 21.4 0.0 1.5 1 1 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.12 KPI40042.1 - 0.00031 20.4 0.1 0.00066 19.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KPI40042.1 - 0.0028 17.4 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Cupin JmjC PF02373.22 KPI40042.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase EutQ PF06249.12 KPI40042.1 - 0.023 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ GPI PF06560.11 KPI40042.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Hemerythrin PF01814.23 KPI40043.1 - 0.0052 17.4 8.0 0.0086 16.7 8.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PAX PF00292.18 KPI40043.1 - 0.1 12.5 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 'Paired box' domain WLM PF08325.10 KPI40044.1 - 1.4e-30 106.8 1.7 5.3e-30 104.9 0.6 2.3 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KPI40044.1 - 1.9e-08 34.6 0.9 4.2e-08 33.5 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF45 Herpes_DNAp_acc PF04929.12 KPI40044.1 - 7.1 5.5 11.5 11 4.8 11.5 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Zn_clus PF00172.18 KPI40045.1 - 2.2e-09 37.3 7.5 4.4e-09 36.3 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI40045.1 - 0.0006 18.9 0.2 0.0012 17.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ubiquitin_4 PF18036.1 KPI40045.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain ADH_zinc_N PF00107.26 KPI40046.1 - 7.9e-27 93.8 0.1 1.2e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI40046.1 - 1.8e-22 80.8 0.0 2.9e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI40046.1 - 0.027 14.4 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Sulfotransfer_4 PF17784.1 KPI40047.1 - 2.3e-18 66.8 0.0 2.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain ABC_tran PF00005.27 KPI40048.1 - 1e-30 107.0 0.0 4.4e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KPI40048.1 - 1.3e-22 80.7 6.3 1.3e-22 80.7 6.3 2.0 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 KPI40048.1 - 5.6e-05 22.7 0.0 0.0029 17.1 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KPI40048.1 - 0.0003 21.2 1.1 0.0023 18.4 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI40048.1 - 0.012 15.9 1.7 0.052 13.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KPI40048.1 - 0.012 15.4 0.6 0.061 13.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPI40048.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KPI40048.1 - 0.017 14.9 3.6 0.077 12.8 0.1 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KPI40048.1 - 0.041 13.2 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KPI40048.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 KPI40048.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 KPI40048.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 KPI40048.1 - 0.094 12.8 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain TsaE PF02367.17 KPI40048.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KPI40048.1 - 0.11 12.7 0.3 1.1 9.5 0.1 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KPI40048.1 - 0.16 12.5 0.1 0.31 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KPI40048.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KPI40048.1 - 0.21 11.3 1.1 0.54 10.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain FAA_hydrolase PF01557.18 KPI40049.1 - 9.7e-50 169.2 0.0 1.3e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPI40049.1 - 2.4e-22 79.2 0.0 3.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Luteo_Vpg PF01659.16 KPI40051.1 - 0.00089 19.6 2.7 0.00089 19.6 2.7 3.3 2 1 0 3 3 3 1 Luteovirus putative VPg genome linked protein DnaJ_C PF01556.18 KPI40053.1 - 9.7e-38 129.6 0.3 1.3e-37 129.2 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPI40053.1 - 2.2e-28 98.1 1.6 3.6e-28 97.5 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain Malate_DH PF12434.8 KPI40053.1 - 0.038 14.0 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Malate dehydrogenase enzyme DUF572 PF04502.13 KPI40054.1 - 5.1e-62 210.4 0.0 5.7e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) GFA PF04828.14 KPI40055.1 - 3.6e-18 65.7 1.0 6.2e-18 64.9 1.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF432 PF04254.13 KPI40055.1 - 0.037 14.2 0.0 0.082 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF432) AA_permease_2 PF13520.6 KPI40056.1 - 1.1e-50 172.7 48.0 3.9e-48 164.3 48.0 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI40056.1 - 3e-09 36.0 39.0 2e-05 23.4 9.2 2.2 1 1 1 2 2 2 2 Amino acid permease DUF5592 PF17332.2 KPI40056.1 - 0.21 12.1 2.9 0.25 11.9 1.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Complex1_30kDa PF00329.19 KPI40057.1 - 7.5e-45 152.5 0.0 1e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF4267 PF14087.6 KPI40058.1 - 2.3e-24 85.6 2.0 2.9e-24 85.3 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.6 KPI40058.1 - 0.055 13.4 3.8 0.073 13.0 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) DUF4064 PF13273.6 KPI40058.1 - 0.4 11.0 4.9 0.79 10.0 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) KH_1 PF00013.29 KPI40059.1 - 3.3e-82 270.3 23.4 1e-13 50.9 0.3 10.8 11 0 0 11 11 11 8 KH domain KH_4 PF13083.6 KPI40059.1 - 1.8e-12 46.9 7.7 0.028 14.3 0.0 6.8 6 0 0 6 6 6 4 KH domain KH_2 PF07650.17 KPI40059.1 - 6.8e-09 35.4 16.9 0.19 11.6 0.0 7.0 6 0 0 6 6 6 4 KH domain SLS PF14611.6 KPI40059.1 - 5.6e-08 32.9 5.0 0.42 10.4 0.0 6.3 5 1 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator BMC PF00936.19 KPI40059.1 - 0.0067 16.4 1.7 2.2 8.3 0.1 4.1 3 0 0 3 3 3 1 BMC domain DUF3218 PF11508.8 KPI40059.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) MOEP19 PF16005.5 KPI40059.1 - 0.16 12.0 0.0 45 4.1 0.0 3.3 3 0 0 3 3 3 0 KH-like RNA-binding domain YqgF PF14639.6 KPI40059.1 - 0.18 11.5 0.8 35 4.2 0.2 3.3 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 KH_5 PF13184.6 KPI40059.1 - 2.1 8.5 16.0 21 5.3 0.2 5.7 6 0 0 6 6 6 0 NusA-like KH domain SHNi-TPR PF10516.9 KPI40060.1 - 4.9e-10 38.7 4.7 6.1e-10 38.4 1.1 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KPI40060.1 - 0.0012 19.0 8.6 0.011 16.0 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPI40060.1 - 0.02 14.7 5.4 2 8.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPI40060.1 - 0.28 11.5 3.1 25 5.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Syntaxin-18_N PF10496.9 KPI40060.1 - 0.32 11.3 2.0 1.6 9.1 0.1 2.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_10 PF13374.6 KPI40060.1 - 0.79 9.7 5.5 7.5 6.6 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI40060.1 - 0.79 10.0 13.8 1.3 9.3 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat P16-Arc PF04699.14 KPI40060.1 - 3.1 8.3 5.4 0.77 10.2 1.3 2.1 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) CCDC-167 PF15188.6 KPI40060.1 - 6.7 7.1 9.6 0.42 11.0 3.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HSP70 PF00012.20 KPI40061.1 - 4.5e-256 850.8 14.3 5.5e-256 850.5 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPI40061.1 - 2.9e-20 72.4 3.2 1.5e-19 70.0 0.9 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KPI40061.1 - 0.033 13.9 0.0 0.54 9.9 0.0 2.7 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KPI40061.1 - 0.23 11.9 6.0 14 6.2 0.4 3.7 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 KPI40061.1 - 0.94 8.7 6.3 0.29 10.3 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase tRNA-synt_2 PF00152.20 KPI40062.1 - 8.2e-63 212.4 0.0 9.1e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) PRCC PF10253.9 KPI40063.1 - 1.2e-37 130.8 3.3 1.2e-37 130.8 3.3 2.0 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting TFIIF_alpha PF05793.12 KPI40064.1 - 0.18 10.4 12.3 0.41 9.2 12.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIB_C_1 PF18542.1 KPI40065.1 - 0.015 15.3 1.0 0.063 13.3 1.0 1.9 1 1 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Terpene_synth_C PF03936.16 KPI40065.1 - 0.046 13.1 0.1 0.054 12.8 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Metallophos PF00149.28 KPI40066.1 - 2.2e-07 31.6 0.0 2.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KPI40066.1 - 1.5e-05 25.2 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UDG PF03167.19 KPI40067.1 - 1.7e-19 70.4 0.1 3.8e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PX PF00787.24 KPI40067.1 - 1.2e-16 60.7 0.0 3.5e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KPI40067.1 - 4.6e-05 23.1 15.1 0.016 14.7 4.4 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Josephin PF02099.17 KPI40067.1 - 0.12 12.4 0.2 0.36 10.9 0.2 1.7 1 0 0 1 1 1 0 Josephin Peptidase_C10 PF01640.17 KPI40067.1 - 0.17 12.2 0.7 0.33 11.3 0.7 1.4 1 0 0 1 1 1 0 Peptidase C10 family BAR_3 PF16746.5 KPI40067.1 - 1.4 8.6 6.1 5.5 6.6 0.1 2.7 2 1 0 2 2 2 0 BAR domain of APPL family Arfaptin PF06456.13 KPI40067.1 - 9.9 5.7 7.2 0.35 10.4 0.2 2.1 3 0 0 3 3 3 0 Arfaptin-like domain MRJP PF03022.16 KPI40068.1 - 1.1e-19 70.9 0.1 1.4e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 KPI40068.1 - 0.066 13.3 0.5 49 4.2 0.0 3.8 3 0 0 3 3 3 0 NHL repeat HSP33 PF01430.19 KPI40069.1 - 0.013 14.9 0.1 0.019 14.4 0.1 1.1 1 0 0 1 1 1 0 Hsp33 protein MFS_1 PF07690.16 KPI40070.1 - 6.3e-23 81.3 39.4 6.3e-23 81.3 39.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF373 PF04123.13 KPI40070.1 - 0.067 12.6 2.5 0.13 11.6 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Mobilization_B PF17511.2 KPI40070.1 - 0.085 13.2 1.6 0.19 12.1 1.6 1.5 1 0 0 1 1 1 0 Mobilization protein B FAD_binding_3 PF01494.19 KPI40071.1 - 5.4e-16 58.8 0.0 2.6e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KPI40071.1 - 0.031 14.5 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI40071.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Mito_carr PF00153.27 KPI40072.1 - 5.3e-43 144.9 0.4 5.4e-14 51.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5134 PF17197.4 KPI40073.1 - 0.019 14.9 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) 4HBT PF03061.22 KPI40074.1 - 3.1e-12 46.7 0.1 5.2e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KPI40074.1 - 0.025 14.7 0.2 0.031 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Epimerase PF01370.21 KPI40076.1 - 2.4e-12 46.8 0.8 1.5e-09 37.7 0.3 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI40076.1 - 8e-08 32.1 0.4 0.00028 20.4 0.1 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPI40076.1 - 2e-07 31.1 2.6 6.4e-07 29.4 1.8 2.0 1 1 1 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPI40076.1 - 6.2e-06 25.5 0.0 0.013 14.6 0.1 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 KPI40076.1 - 1.1e-05 25.1 0.7 5.6e-05 22.8 0.4 2.1 2 1 0 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.12 KPI40076.1 - 0.00081 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KPI40076.1 - 0.0017 17.8 0.3 0.0039 16.7 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KPI40076.1 - 0.002 17.2 0.1 0.0045 16.0 0.1 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.14 KPI40076.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VIT1 PF01988.19 KPI40078.1 - 0.4 10.5 5.0 0.59 10.0 4.9 1.4 1 1 0 1 1 1 0 VIT family Rhodanese PF00581.20 KPI40079.1 - 4.6e-14 52.9 0.0 1.3e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Glyoxalase_6 PF18029.1 KPI40080.1 - 0.00025 21.8 0.0 0.00036 21.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KPI40080.1 - 0.086 13.1 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 KPI40081.1 - 3.6e-36 124.5 0.0 4.5e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40081.1 - 6.7e-29 101.1 0.0 9e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40081.1 - 1.7e-05 24.8 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KPI40081.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KPI40081.1 - 0.015 15.0 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 KPI40081.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ACPS PF01648.20 KPI40082.1 - 2.3e-08 34.2 0.1 1.4e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PFU PF09070.11 KPI40084.1 - 1.6e-43 147.6 0.8 2.7e-43 146.8 0.8 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KPI40084.1 - 6.6e-40 137.1 4.0 8.8e-40 136.7 4.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KPI40084.1 - 2.3e-25 88.3 10.7 3.3e-05 24.5 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TRP PF06011.12 KPI40085.1 - 1.9e-138 461.8 18.9 2.5e-138 461.4 18.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPI40085.1 - 3e-39 134.6 0.1 5.3e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 ML-like domain FAM176 PF14851.6 KPI40085.1 - 0.2 11.3 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 FAM176 family Shisa PF13908.6 KPI40085.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.5 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KPI40085.1 - 9.1 7.2 0.0 9.1 7.2 0.0 4.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Flavokinase PF01687.17 KPI40086.1 - 1.4e-32 112.3 0.0 1.7e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ank_4 PF13637.6 KPI40087.1 - 2.8e-05 24.6 0.1 0.42 11.3 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI40087.1 - 0.0047 17.5 0.0 0.13 12.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPI40087.1 - 0.022 15.2 0.0 0.074 13.5 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat OGG_N PF07934.12 KPI40088.1 - 2.5e-33 114.8 0.0 3.9e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KPI40088.1 - 1.5e-10 41.5 0.0 2.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zinc_ribbon_5 PF13719.6 KPI40089.1 - 0.084 12.6 22.3 3.5 7.5 0.4 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 KPI40089.1 - 0.14 11.9 16.5 3.2 7.6 0.4 4.4 4 0 0 4 4 4 0 InsA N-terminal domain AID PF18767.1 KPI40089.1 - 0.78 9.8 4.1 4.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Activation induced deaminase zf-FPG_IleRS PF06827.14 KPI40089.1 - 5.8 6.9 17.3 13 5.7 0.9 4.3 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS RNase_PH PF01138.21 KPI40090.1 - 3.8e-23 82.4 0.0 5.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KPI40090.1 - 4.1e-06 26.7 0.1 9.2e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RT_RNaseH PF17917.1 KPI40090.1 - 0.018 15.3 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KPI40090.1 - 0.056 13.5 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase SPOC PF07744.13 KPI40091.1 - 4.9e-18 65.5 0.0 1.2e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KPI40091.1 - 6.9e-12 45.8 0.3 2.1e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KPI40091.1 - 2.4e-09 36.9 12.3 5.4e-09 35.8 12.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KPI40091.1 - 0.0029 17.1 6.4 0.0056 16.2 6.4 1.4 1 0 0 1 1 1 1 PHD-finger zinc_ribbon_10 PF10058.9 KPI40091.1 - 0.2 11.4 7.7 0.52 10.1 7.7 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_3 PF13922.6 KPI40091.1 - 0.87 10.0 3.4 3.7 8.0 3.4 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Aldo_ket_red PF00248.21 KPI40092.1 - 2.3e-62 210.9 0.0 2.6e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 KPI40093.1 - 2.3e-08 33.7 1.2 0.016 14.5 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KPI40093.1 - 0.0073 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI40093.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI40093.1 - 0.04 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40093.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI40093.1 - 0.09 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 KPI40094.1 - 4.6e-40 134.9 23.7 1.2e-09 38.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI40094.1 - 7.9e-08 32.5 0.3 0.14 12.5 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI40094.1 - 6.8e-05 21.7 5.1 0.087 11.4 0.2 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KPI40094.1 - 0.01 15.2 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 KPI40094.1 - 0.011 14.3 0.0 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KPI40094.1 - 0.042 13.8 1.3 22 5.1 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat zf-LITAF-like PF10601.9 KPI40095.1 - 3.4e-16 59.3 10.3 4.6e-16 58.8 10.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain CENP-R PF06729.12 KPI40095.1 - 1.1 9.2 4.7 1.7 8.6 4.7 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R Glyco_hydro_31 PF01055.26 KPI40096.1 - 7e-93 312.2 6.6 9.9e-93 311.7 6.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.24 KPI40097.1 - 3.3e-107 359.2 18.9 4.1e-107 358.8 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40097.1 - 6.4e-24 84.5 30.5 8.5e-24 84.1 25.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KPI40097.1 - 0.00037 19.5 0.4 0.001 18.1 0.4 1.7 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM VHS PF00790.19 KPI40098.1 - 2.4e-40 137.6 3.9 5.4e-40 136.5 0.4 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KPI40098.1 - 3.6e-16 59.1 2.2 6.3e-16 58.3 2.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KPI40098.1 - 2.4e-07 30.2 11.6 0.0022 17.8 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 KPI40098.1 - 6.1e-05 23.2 0.3 0.00029 21.1 0.0 2.3 3 0 0 3 3 3 1 GAT domain FYVE_2 PF02318.16 KPI40098.1 - 0.044 14.0 0.5 0.098 12.9 0.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger ENTH PF01417.20 KPI40098.1 - 0.055 13.5 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 ENTH domain Cnd1 PF12717.7 KPI40098.1 - 0.074 13.1 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CTD_bind PF04818.13 KPI40098.1 - 0.085 13.7 0.0 0.38 11.6 0.0 2.1 2 0 0 2 2 1 0 RNA polymerase II-binding domain. Ribosomal_S30AE PF02482.19 KPI40098.1 - 0.11 13.3 0.0 0.95 10.3 0.2 2.4 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein C1_1 PF00130.22 KPI40098.1 - 0.13 12.2 3.0 0.26 11.2 3.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RTTN_N PF14726.6 KPI40098.1 - 0.21 12.4 0.3 0.59 11.0 0.1 1.8 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning OAD_gamma PF04277.13 KPI40098.1 - 0.66 10.6 1.7 1.8 9.2 0.8 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Amidohydro_1 PF01979.20 KPI40099.1 - 2e-06 27.4 0.0 1.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI40099.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family TGT_C2 PF14810.6 KPI40099.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase AAA_5 PF07728.14 KPI40100.1 - 4e-121 399.4 0.1 4.1e-21 75.4 0.0 10.0 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KPI40100.1 - 1.7e-44 150.3 4.5 6.9e-18 64.8 0.0 5.9 6 0 0 6 6 4 3 Midasin AAA lid domain AAA_3 PF07726.11 KPI40100.1 - 2e-29 102.1 0.0 1.2e-12 47.8 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KPI40100.1 - 3.4e-25 88.2 0.0 1.5e-24 86.1 0.0 2.3 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 KPI40100.1 - 4.3e-24 85.4 0.0 0.00025 21.5 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KPI40100.1 - 1.7e-22 79.7 0.0 7.6e-05 22.8 0.0 7.1 6 1 0 6 6 5 5 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KPI40100.1 - 7.2e-22 77.8 1.1 0.00015 21.3 0.0 6.0 6 0 0 6 6 5 4 P-loop containing dynein motor region AAA_16 PF13191.6 KPI40100.1 - 4.3e-20 72.8 21.5 0.00026 21.4 1.4 9.7 7 2 0 7 7 7 4 AAA ATPase domain AAA_6 PF12774.7 KPI40100.1 - 1.5e-17 63.6 0.0 0.036 13.0 0.0 8.7 9 2 0 9 9 8 4 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KPI40100.1 - 2.7e-14 53.8 1.0 0.47 11.0 0.0 7.3 6 0 0 6 6 6 2 AAA domain AAA_22 PF13401.6 KPI40100.1 - 4.2e-12 46.5 0.7 0.43 10.9 0.0 8.0 7 0 0 7 7 7 2 AAA domain TsaE PF02367.17 KPI40100.1 - 8.2e-11 42.0 0.6 1 9.3 0.0 6.3 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KPI40100.1 - 4.7e-10 39.2 0.8 4.6 6.6 0.0 8.4 7 1 0 7 7 7 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KPI40100.1 - 8.6e-10 38.6 0.1 0.31 10.7 0.0 5.2 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_19 PF13245.6 KPI40100.1 - 9.9e-10 38.9 1.1 0.02 15.2 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KPI40100.1 - 1.3e-09 38.0 3.6 0.082 12.6 0.0 6.9 7 1 0 7 7 7 2 AAA domain AAA_33 PF13671.6 KPI40100.1 - 3.7e-09 36.9 0.1 1.7 8.8 0.0 6.7 6 0 0 6 6 6 1 AAA domain ABC_tran PF00005.27 KPI40100.1 - 1.2e-08 35.5 0.4 0.98 9.9 0.0 6.1 5 0 0 5 5 5 2 ABC transporter RNA_helicase PF00910.22 KPI40100.1 - 5.4e-08 33.2 0.5 6 7.3 0.0 6.4 6 0 0 6 6 6 0 RNA helicase NACHT PF05729.12 KPI40100.1 - 6.2e-08 32.7 2.9 0.042 13.7 0.1 5.1 5 0 0 5 5 4 2 NACHT domain RuvB_N PF05496.12 KPI40100.1 - 1.1e-07 31.8 3.6 0.52 10.1 0.0 5.9 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KPI40100.1 - 6.9e-07 28.7 0.9 0.069 12.4 0.0 5.1 5 0 0 5 5 5 1 Zeta toxin AAA_25 PF13481.6 KPI40100.1 - 1.2e-06 28.2 3.8 0.73 9.4 0.0 5.7 5 0 0 5 5 5 1 AAA domain Sigma54_activ_2 PF14532.6 KPI40100.1 - 1.9e-06 28.0 0.1 0.59 10.3 0.0 5.2 4 0 0 4 4 4 1 Sigma-54 interaction domain DUF815 PF05673.13 KPI40100.1 - 2.3e-06 27.0 1.5 2.1 7.4 0.0 4.5 4 0 0 4 4 4 2 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KPI40100.1 - 4.7e-06 26.6 2.8 0.067 13.1 0.1 5.1 5 0 0 5 5 5 1 RsgA GTPase TIP49 PF06068.13 KPI40100.1 - 1.1e-05 24.9 0.9 0.077 12.2 0.0 3.8 4 0 0 4 4 4 2 TIP49 P-loop domain AAA_29 PF13555.6 KPI40100.1 - 1.3e-05 24.8 0.4 4.8 7.0 0.0 4.9 5 0 0 5 5 4 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KPI40100.1 - 4.3e-05 23.8 2.9 30 4.8 0.0 6.5 6 0 0 6 6 6 0 AAA domain Viral_helicase1 PF01443.18 KPI40100.1 - 5.2e-05 23.1 0.3 0.17 11.6 0.0 4.9 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KPI40100.1 - 6e-05 23.1 0.0 3.5 7.6 0.0 4.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KPI40100.1 - 8.6e-05 22.6 0.0 6 6.7 0.0 5.1 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KPI40100.1 - 0.00013 21.7 0.2 9.7 5.9 0.0 4.8 6 0 0 6 6 4 0 IstB-like ATP binding protein Roc PF08477.13 KPI40100.1 - 0.00031 21.0 2.5 1.5 9.0 0.1 5.4 6 0 0 6 6 5 1 Ras of Complex, Roc, domain of DAPkinase Bac_DnaA PF00308.18 KPI40100.1 - 0.00034 20.5 0.0 0.54 10.0 0.0 4.6 5 0 0 5 5 5 1 Bacterial dnaA protein PduV-EutP PF10662.9 KPI40100.1 - 0.00035 20.3 0.7 1.6 8.5 0.0 4.1 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KPI40100.1 - 0.00079 18.9 0.0 10 5.5 0.0 4.9 5 0 0 5 5 5 0 Bacterial TniB protein AAA_8 PF12780.7 KPI40100.1 - 0.0015 17.9 0.1 8.9 5.5 0.0 4.2 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 AAA_24 PF13479.6 KPI40100.1 - 0.0058 16.4 0.1 13 5.5 0.0 4.8 6 0 0 6 6 5 0 AAA domain T2SSE PF00437.20 KPI40100.1 - 0.0084 15.2 8.7 0.42 9.6 0.0 5.7 7 0 0 7 7 7 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KPI40100.1 - 0.0088 16.1 5.3 11 6.1 0.0 5.4 6 0 0 6 6 5 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KPI40100.1 - 0.015 15.2 9.0 12 5.7 0.0 5.1 5 0 0 5 5 5 0 NTPase SRP54 PF00448.22 KPI40100.1 - 0.016 14.8 2.6 50 3.4 0.0 4.4 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KPI40100.1 - 0.018 15.1 0.0 20 5.2 0.0 4.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 KPI40100.1 - 0.021 14.2 0.1 25 4.1 0.0 4.5 5 0 0 5 5 5 0 KaiC DEAD PF00270.29 KPI40100.1 - 0.042 13.6 0.4 42 3.9 0.0 4.2 4 0 0 4 4 4 0 DEAD/DEAH box helicase PhoH PF02562.16 KPI40100.1 - 0.045 13.2 1.0 6.2 6.2 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein DnaB_C PF03796.15 KPI40100.1 - 0.049 13.0 5.5 17 4.6 0.0 5.5 6 0 0 6 6 6 0 DnaB-like helicase C terminal domain cobW PF02492.19 KPI40100.1 - 3.3 7.3 8.1 20 4.7 0.1 4.5 6 0 0 6 6 4 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KPI40100.1 - 7.9 6.2 9.9 9.4 5.9 0.1 4.4 6 0 0 6 6 4 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.27 KPI40101.1 - 2.4e-54 181.2 2.4 1.3e-17 63.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAN_1 PF00024.26 KPI40102.1 - 2.6e-12 46.5 3.1 3.9e-05 23.5 0.1 3.2 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 KPI40102.1 - 6.4e-11 42.0 5.3 2.7e-05 24.0 0.5 2.5 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 KPI40102.1 - 0.00063 20.0 0.3 0.25 11.7 0.1 2.8 2 0 0 2 2 2 2 MANEC domain PAN_2 PF08276.11 KPI40102.1 - 0.024 14.7 5.6 0.8 9.9 0.3 2.7 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.12 KPI40102.1 - 0.12 12.2 1.7 11 5.9 0.2 3.0 2 0 0 2 2 2 0 PAN-like domain CBFB_NFYA PF02045.15 KPI40103.1 - 0.0097 16.5 1.6 0.014 16.0 1.6 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Peptidase_M20 PF01546.28 KPI40106.1 - 9.7e-16 58.1 0.1 1.3e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI40106.1 - 9.7e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPI40106.1 - 0.044 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Caveolin PF01146.17 KPI40106.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Caveolin SCA7 PF08313.12 KPI40107.1 - 3.2e-31 107.0 0.9 3.2e-31 107.0 0.9 2.3 2 2 0 3 3 3 1 SCA7, zinc-binding domain CDC45 PF02724.14 KPI40107.1 - 0.074 11.3 12.6 0.081 11.2 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC71L PF15374.6 KPI40107.1 - 2.6 7.2 19.4 5.2 6.2 19.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L TLP-20 PF06088.11 KPI40107.1 - 2.8 7.8 9.1 4.5 7.1 9.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleo_P87 PF07267.11 KPI40107.1 - 4.5 6.0 12.6 6.1 5.6 12.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF913 PF06025.12 KPI40107.1 - 5.1 6.0 6.7 7 5.5 6.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCM_bind PF09739.9 KPI40107.1 - 5.7 5.3 7.8 7.5 4.9 7.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SAPS PF04499.15 KPI40107.1 - 6.5 5.4 6.9 7.4 5.2 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.9 KPI40107.1 - 8.3 4.9 8.8 10 4.6 8.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 KPI40107.1 - 8.5 5.5 5.2 10 5.2 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2306 PF10067.9 KPI40108.1 - 1.8e-12 47.7 10.1 3.3e-12 46.8 10.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 KPI40108.1 - 0.0024 18.1 4.2 0.0024 18.1 4.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF420) Per1 PF04080.13 KPI40108.1 - 0.57 9.9 4.7 0.94 9.2 4.7 1.3 1 0 0 1 1 1 0 Per1-like family DUF2070 PF09843.9 KPI40108.1 - 0.83 7.9 7.9 1.1 7.5 7.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5336 PF17270.2 KPI40108.1 - 1.3 8.7 5.0 12 5.5 0.8 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5336) Apolipoprotein PF01442.18 KPI40109.1 - 0.023 14.6 33.3 0.98 9.3 2.2 7.8 6 4 0 6 6 6 0 Apolipoprotein A1/A4/E domain Fungal_trans PF04082.18 KPI40110.1 - 6.7e-10 38.4 2.0 1.9e-09 37.0 1.9 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 KPI40111.1 - 1.8e-24 86.3 0.0 1.6e-18 66.9 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40111.1 - 1.9e-15 57.1 0.0 6.8e-12 45.4 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40111.1 - 4.7e-07 29.9 0.1 9.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI40111.1 - 0.0026 17.3 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI40111.1 - 0.013 14.7 0.1 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein Shikimate_DH PF01488.20 KPI40111.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M24 PF00557.24 KPI40112.1 - 3.1e-40 138.1 0.2 4.8e-39 134.2 0.2 2.3 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KPI40112.1 - 4.7e-38 129.7 0.0 8.2e-38 128.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Asp_Glu_race PF01177.22 KPI40114.1 - 3.6e-41 141.5 0.0 4e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase zf-RING_4 PF14570.6 KPI40115.1 - 1.4e-17 63.2 13.3 2.3e-17 62.5 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KPI40115.1 - 1.8e-07 30.9 7.7 3.1e-07 30.2 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI40115.1 - 0.00041 20.6 11.2 0.00076 19.8 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.22 KPI40115.1 - 0.00085 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 KPI40115.1 - 0.0032 16.9 3.9 0.0032 16.9 3.9 4.2 4 1 1 5 5 4 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 KPI40115.1 - 0.006 16.4 9.5 0.16 11.8 10.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3H1 PF10650.9 KPI40115.1 - 0.12 12.2 0.4 0.27 11.0 0.4 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain zf-TFIIIC PF12660.7 KPI40115.1 - 0.27 11.2 1.7 0.57 10.2 1.7 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex FYVE PF01363.21 KPI40115.1 - 0.33 11.1 3.7 0.8 9.9 3.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.6 KPI40115.1 - 0.46 10.5 11.7 0.77 9.8 11.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KPI40115.1 - 0.75 9.7 12.1 1.3 8.9 12.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KPI40115.1 - 1.4 8.9 6.7 2.5 8.0 6.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 KPI40115.1 - 3.3 7.8 10.1 18 5.4 10.4 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 KPI40115.1 - 7.3 6.5 11.2 13 5.7 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.18 KPI40116.1 - 1.5e-06 27.4 0.0 2.7e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mob1_phocein PF03637.17 KPI40116.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Mob1/phocein family UCH PF00443.29 KPI40117.1 - 1.6e-70 237.6 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI40117.1 - 9.9e-13 48.4 0.0 1.4e-06 28.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Actin_micro PF17003.5 KPI40117.1 - 0.14 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Putative actin-like family Dishevelled PF02377.15 KPI40117.1 - 2.8 8.4 8.5 18 5.7 0.1 3.0 2 0 0 2 2 2 0 Dishevelled specific domain Peptidase_M48 PF01435.18 KPI40118.1 - 2.4e-33 115.6 0.0 3.7e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 MAPEG PF01124.18 KPI40119.1 - 6.2e-21 74.7 1.7 8.2e-21 74.3 1.7 1.1 1 0 0 1 1 1 1 MAPEG family SCP1201-deam PF14428.6 KPI40119.1 - 0.073 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 SCP1.201-like deaminase Fungal_trans_2 PF11951.8 KPI40120.1 - 2.5e-13 49.6 0.1 3.3e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AIRC PF00731.20 KPI40121.1 - 1.6e-27 95.9 0.1 2e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 AIR carboxylase DUF746 PF05344.11 KPI40121.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Spc7 PF08317.11 KPI40122.1 - 6.3e-06 25.3 68.1 0.0024 16.8 21.0 3.3 2 1 1 3 3 3 3 Spc7 kinetochore protein Filament PF00038.21 KPI40122.1 - 0.0031 17.2 65.6 0.0043 16.7 41.9 2.6 2 2 0 2 2 2 2 Intermediate filament protein MscS_porin PF12795.7 KPI40122.1 - 0.0054 16.3 12.9 0.0054 16.3 12.9 3.9 1 1 3 4 4 4 3 Mechanosensitive ion channel porin domain Cnn_1N PF07989.11 KPI40122.1 - 0.012 15.8 4.4 0.012 15.8 4.4 6.9 5 2 1 6 6 6 0 Centrosomin N-terminal motif 1 Laminin_II PF06009.12 KPI40122.1 - 0.033 14.2 0.8 0.033 14.2 0.8 5.8 2 1 3 6 6 6 0 Laminin Domain II SlyX PF04102.12 KPI40122.1 - 0.037 14.7 0.3 0.037 14.7 0.3 7.8 4 3 4 8 8 8 0 SlyX DUF4508 PF14969.6 KPI40122.1 - 0.053 13.8 1.9 4.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) DASH_Dam1 PF08653.10 KPI40122.1 - 0.085 12.7 2.0 8.9 6.2 0.2 3.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 KPI40122.1 - 0.22 11.7 41.2 0.38 10.9 0.8 4.4 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KPI40122.1 - 0.23 11.6 75.8 0.098 12.8 9.2 4.5 1 1 2 4 4 4 0 Tropomyosin like GAS PF13851.6 KPI40122.1 - 0.27 10.6 76.9 0.041 13.2 17.0 5.4 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding DSS1_SEM1 PF05160.13 KPI40122.1 - 0.68 10.0 10.0 0.19 11.8 4.8 2.6 2 0 0 2 2 2 0 DSS1/SEM1 family ATG16 PF08614.11 KPI40122.1 - 1.9 8.6 82.8 2.4 8.3 10.1 4.9 2 2 1 4 4 4 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KPI40122.1 - 2.4 8.2 65.4 0.092 12.8 3.2 5.4 2 1 3 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KPI40122.1 - 3 8.1 62.1 0.061 13.6 4.1 6.2 2 2 5 7 7 7 0 TATA element modulatory factor 1 TATA binding 2-Hacid_dh_C PF02826.19 KPI40123.1 - 6.2e-55 185.3 0.0 9.9e-55 184.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI40123.1 - 7.5e-37 126.0 0.0 1.9e-36 124.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KPI40123.1 - 0.017 14.9 0.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 ACT domain XdhC_C PF13478.6 KPI40123.1 - 0.025 15.1 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain TAL_FSA PF00923.19 KPI40124.1 - 6.6e-35 120.8 0.0 1.1e-34 120.1 0.0 1.3 2 0 0 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase Psu PF07455.11 KPI40124.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) SecY PF00344.20 KPI40125.1 - 0.0025 17.1 0.1 1.1 8.5 0.0 2.4 1 1 1 2 2 2 2 SecY translocase DUF5134 PF17197.4 KPI40125.1 - 0.31 10.9 9.6 0.76 9.7 0.3 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF5134) DUF2834 PF11196.8 KPI40125.1 - 0.56 10.6 11.6 0.74 10.2 0.9 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2834) MFS_1 PF07690.16 KPI40126.1 - 6e-36 124.1 43.6 2.2e-33 115.7 27.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4013 PF13197.6 KPI40128.1 - 0.34 10.7 13.1 0.91 9.4 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) DEAD PF00270.29 KPI40129.1 - 6.3e-50 169.4 0.0 2e-49 167.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI40129.1 - 6.9e-32 110.1 0.1 1.2e-29 102.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI40129.1 - 9.3e-08 32.3 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KPI40129.1 - 0.00018 20.8 0.0 0.00064 19.0 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KPI40129.1 - 0.0013 19.0 0.0 0.0073 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPI40129.1 - 0.017 14.8 0.1 0.042 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 KPI40129.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF108 PF01958.18 KPI40129.1 - 0.14 12.5 0.0 0.5 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF108 SBF PF01758.16 KPI40130.1 - 6.3e-49 166.3 10.7 1.6e-48 165.0 10.7 1.7 1 0 0 1 1 1 1 Sodium Bile acid symporter family DHFR_1 PF00186.19 KPI40131.1 - 5.1e-21 75.0 0.0 4.6e-09 36.2 0.0 3.2 3 0 0 3 3 3 3 Dihydrofolate reductase SRP-alpha_N PF04086.13 KPI40132.1 - 0.37 10.7 8.2 0.57 10.1 8.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MIF4G_like PF09088.11 KPI40132.1 - 0.41 10.4 2.7 16 5.2 0.7 2.1 2 0 0 2 2 2 0 MIF4G like Raf1_N PF18578.1 KPI40133.1 - 0.00066 20.1 0.4 1.3 9.5 0.1 2.5 1 1 1 2 2 2 2 Rubisco accumulation factor 1 alpha helical domain TetR_C_20 PF17925.1 KPI40133.1 - 0.26 11.6 7.8 24 5.3 0.1 4.4 3 2 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PNP_UDP_1 PF01048.20 KPI40134.1 - 9.4e-27 93.8 0.2 2.2e-26 92.6 0.1 1.5 1 1 1 2 2 2 1 Phosphorylase superfamily CTP_transf_like PF01467.26 KPI40135.1 - 2.3e-19 70.0 0.0 3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like zf-Nse PF11789.8 KPI40136.1 - 4.6e-17 61.6 0.1 9.6e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit NOA36 PF06524.12 KPI40136.1 - 0.15 11.3 28.1 0.14 11.5 7.6 3.3 3 0 0 3 3 3 0 NOA36 protein zf-RING_UBOX PF13445.6 KPI40136.1 - 0.16 12.1 0.1 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger Rtf2 PF04641.12 KPI40136.1 - 0.2 11.0 6.9 3.5 6.9 3.6 2.8 3 0 0 3 3 3 0 Rtf2 RING-finger DUF1682 PF07946.14 KPI40136.1 - 0.31 10.2 4.6 0.62 9.2 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DPPIV_N PF00930.21 KPI40137.1 - 9.9e-86 287.7 0.3 1.1e-83 281.0 0.3 2.2 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KPI40137.1 - 4.8e-50 170.0 0.3 8.8e-50 169.1 0.3 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KPI40137.1 - 8.6e-05 23.2 1.4 0.0068 17.0 0.0 3.2 2 1 2 4 4 4 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KPI40137.1 - 0.0028 17.3 1.1 0.0094 15.6 0.7 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KPI40137.1 - 0.035 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KPI40137.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.12 KPI40137.1 - 0.078 12.9 0.1 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PAF-AH_p_II PF03403.13 KPI40137.1 - 0.19 10.2 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Rft-1 PF04506.13 KPI40138.1 - 3.1e-100 336.3 0.1 6.6e-100 335.3 0.1 1.4 2 0 0 2 2 2 1 Rft protein DUF1328 PF07043.13 KPI40138.1 - 0.5 10.6 7.0 1.9 8.8 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) Rax2 PF12768.7 KPI40139.1 - 1.5e-55 188.0 1.0 2e-53 181.0 0.0 3.9 4 0 0 4 4 4 1 Cortical protein marker for cell polarity Kelch_1 PF01344.25 KPI40139.1 - 0.00036 20.1 1.2 3.8 7.2 0.0 4.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KPI40139.1 - 0.019 15.2 11.5 15 6.1 0.0 5.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_4 PF13418.6 KPI40139.1 - 0.1 12.6 6.5 5.2 7.2 0.4 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF2244 PF10003.9 KPI40139.1 - 0.27 10.9 0.3 0.73 9.5 0.0 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF5122 PF17164.4 KPI40139.1 - 4.2 7.7 18.2 3 8.2 0.2 6.5 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller DUF3425 PF11905.8 KPI40140.1 - 6e-13 48.8 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) OrsD PF12013.8 KPI40141.1 - 0.00019 21.9 0.9 0.00043 20.7 0.5 1.8 1 1 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 KPI40141.1 - 0.00022 21.4 0.1 0.00036 20.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI40141.1 - 0.0035 17.7 0.3 0.0056 17.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KPI40141.1 - 0.094 13.1 0.3 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Methyltransf_23 PF13489.6 KPI40142.1 - 2.1e-17 63.4 0.0 3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI40142.1 - 2.4e-13 50.6 0.0 4.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40142.1 - 1.5e-09 38.4 0.0 2.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40142.1 - 2.2e-09 37.3 0.0 2.2e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI40142.1 - 1.4e-06 28.9 0.0 1e-05 26.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI40142.1 - 0.001 18.4 0.0 0.053 12.9 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPI40142.1 - 0.0067 16.0 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KPI40142.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KPI40142.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KPI40142.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KPI40142.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain MFS_1 PF07690.16 KPI40143.1 - 3.7e-36 124.8 28.2 3.7e-36 124.8 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40143.1 - 1.2e-09 37.6 7.0 1.2e-09 37.6 7.0 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KPI40143.1 - 0.021 13.1 3.8 0.083 11.2 0.8 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EptA_B_N PF08019.12 KPI40143.1 - 1.6 8.6 5.8 27 4.6 0.6 3.4 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Fungal_trans_2 PF11951.8 KPI40144.1 - 1.7e-12 46.9 0.0 3.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI40144.1 - 8.2e-07 29.0 9.2 1.3e-06 28.4 9.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Resolvase PF00239.21 KPI40144.1 - 0.033 14.3 0.2 0.067 13.3 0.2 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain UCH PF00443.29 KPI40145.1 - 2.9e-50 171.2 0.0 4.8e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI40145.1 - 4.1e-19 69.3 0.3 5.7e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KPI40145.1 - 0.00066 20.2 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Rubredoxin PF00301.20 KPI40145.1 - 0.074 13.1 0.1 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 Rubredoxin DUF2457 PF10446.9 KPI40145.1 - 7.2 5.6 8.4 16 4.5 8.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1682 PF07946.14 KPI40146.1 - 3.4e-108 361.7 2.8 4e-108 361.5 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.8 KPI40146.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Pantoate_transf PF02548.15 KPI40147.1 - 2.8e-104 348.1 0.8 3.4e-104 347.8 0.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KPI40147.1 - 8e-10 38.6 1.7 2.6e-09 36.9 1.7 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Sugar_tr PF00083.24 KPI40148.1 - 4.8e-100 335.5 27.0 5.6e-100 335.3 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40148.1 - 4.1e-24 85.2 50.5 8.4e-22 77.6 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Clr5 PF14420.6 KPI40149.1 - 4.6e-13 49.2 2.5 8e-13 48.4 0.2 2.6 3 0 0 3 3 3 1 Clr5 domain TPR_12 PF13424.6 KPI40149.1 - 1.5e-09 38.0 2.1 0.0004 20.6 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI40149.1 - 0.0053 16.7 0.2 28 5.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI40149.1 - 0.025 14.7 0.3 25 5.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI40149.1 - 0.038 13.8 0.0 2.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Phosphoesterase PF04185.14 KPI40149.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 2 0 0 2 2 2 0 Phosphoesterase family TPR_10 PF13374.6 KPI40149.1 - 0.18 11.7 0.0 0.18 11.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PAN_3 PF08277.12 KPI40150.1 - 0.00016 21.4 1.3 0.00016 21.4 1.3 2.2 2 0 0 2 2 2 1 PAN-like domain PAN_1 PF00024.26 KPI40150.1 - 0.00016 21.6 4.3 0.00016 21.6 4.3 2.2 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 KPI40150.1 - 0.011 15.7 2.7 0.023 14.6 2.7 1.5 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 KPI40150.1 - 0.027 14.6 1.2 0.089 12.9 1.2 2.0 1 0 0 1 1 1 0 PAN-like domain SOG2 PF10428.9 KPI40150.1 - 0.077 12.2 16.0 0.098 11.8 16.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pyridoxal_deC PF00282.19 KPI40151.1 - 7.7e-20 70.9 0.0 6.4e-16 58.0 0.0 3.2 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 KPI40151.1 - 0.11 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS YjeF_N PF03853.15 KPI40152.1 - 1.7e-33 115.9 0.0 2.1e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ADH_zinc_N PF00107.26 KPI40153.1 - 1.4e-27 96.2 0.5 2.5e-27 95.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI40153.1 - 8.7e-24 83.5 0.0 2.3e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KPI40153.1 - 1e-10 42.8 0.0 2.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase tRNA_anti-codon PF01336.25 KPI40153.1 - 0.073 13.1 0.1 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain YajC PF02699.15 KPI40153.1 - 0.51 10.3 2.7 0.58 10.1 0.1 2.3 3 0 0 3 3 3 0 Preprotein translocase subunit DUF155 PF02582.14 KPI40154.1 - 1.5e-52 178.3 0.0 2.6e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ras PF00071.22 KPI40154.1 - 1e-34 119.5 0.0 2.6e-20 72.7 0.0 2.3 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KPI40154.1 - 8e-09 35.8 0.0 0.00013 22.1 0.0 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Erg28 PF03694.13 KPI40155.1 - 1.4e-09 38.4 0.3 1.7e-09 38.0 0.3 1.2 1 0 0 1 1 1 1 Erg28 like protein Alg6_Alg8 PF03155.15 KPI40156.1 - 2.6e-171 570.8 28.6 3e-171 570.6 28.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Acetyltransf_7 PF13508.7 KPI40158.1 - 6.5e-09 36.1 0.0 2e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI40158.1 - 1.9e-08 34.6 0.0 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI40158.1 - 2e-07 31.0 0.0 0.00086 19.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI40158.1 - 0.00014 21.7 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.7 KPI40158.1 - 0.0021 18.1 0.7 0.043 13.9 0.1 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 KPI40158.1 - 0.0027 17.5 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_CG PF14542.6 KPI40158.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pyridox_ox_2 PF12900.7 KPI40159.1 - 3.3e-34 117.9 0.0 4.5e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SMP PF04927.12 KPI40160.1 - 3.6e-05 24.2 6.1 1.4 9.5 0.1 4.3 2 1 1 4 4 4 2 Seed maturation protein ASCH PF04266.14 KPI40160.1 - 0.086 13.4 0.6 4.4 7.9 0.0 2.7 2 1 0 2 2 2 0 ASCH domain FAM176 PF14851.6 KPI40161.1 - 0.05 13.3 0.1 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 FAM176 family Salt_tol_Pase PF09506.10 KPI40161.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Lactamase_B PF00753.27 KPI40162.1 - 4.3e-13 49.7 3.3 8.5e-13 48.7 3.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI40162.1 - 0.00023 20.7 0.1 0.00064 19.3 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain MukB_hinge PF16330.5 KPI40164.1 - 0.055 13.2 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 MukB hinge domain Transket_pyr PF02779.24 KPI40165.1 - 9.7e-45 152.4 0.1 1.6e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPI40165.1 - 8.7e-31 106.4 0.2 2e-30 105.3 0.1 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain LEA_3 PF03242.13 KPI40165.1 - 0.017 15.8 1.0 0.036 14.8 1.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein PFOR_II PF17147.4 KPI40165.1 - 0.05 13.9 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II RRM_1 PF00076.22 KPI40166.1 - 2e-18 66.0 0.2 4e-18 65.0 0.2 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPI40166.1 - 0.00047 19.7 0.0 0.00055 19.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KPI40166.1 - 0.061 13.6 0.0 0.09 13.0 0.0 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter ADH_zinc_N PF00107.26 KPI40167.1 - 2.1e-16 60.1 0.0 3.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI40167.1 - 3.9e-16 60.3 0.0 7.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI40167.1 - 0.13 12.1 0.0 9.2 6.2 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Peptidase_M3 PF01432.20 KPI40168.1 - 2.8e-112 376.3 0.0 4.3e-112 375.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KPI40168.1 - 0.071 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Effector protein Peptidase_M50B PF13398.6 KPI40168.1 - 0.12 11.9 0.3 0.21 11.2 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like TetR_C_36 PF18598.1 KPI40168.1 - 0.13 12.3 0.1 11 6.0 0.0 2.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain His_Phos_1 PF00300.22 KPI40169.1 - 2.2e-11 43.8 0.1 1.3e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ribonuc_L-PSP PF01042.21 KPI40170.1 - 7.4e-12 45.4 0.0 9.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Proteasome PF00227.26 KPI40171.1 - 1.2e-59 201.1 0.2 1.4e-59 200.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPI40171.1 - 1.9e-11 43.4 0.1 5.2e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 KPI40171.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5624 PF18538.1 KPI40171.1 - 0.039 14.0 0.4 0.093 12.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Proteasome PF00227.26 KPI40172.1 - 4e-45 153.6 0.1 5.1e-45 153.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KPI40172.1 - 3.9e-14 51.7 1.9 3.9e-14 51.7 1.9 2.0 3 0 0 3 3 3 1 Proteasome beta subunits C terminal RRM_1 PF00076.22 KPI40173.1 - 3.5e-16 58.8 0.0 5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_62 PF03664.13 KPI40174.1 - 1.1e-68 231.5 10.8 1.4e-68 231.2 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Tachylectin PF14517.6 KPI40174.1 - 0.0022 17.6 0.2 0.0042 16.6 0.2 1.4 1 0 0 1 1 1 1 Tachylectin FMO-like PF00743.19 KPI40175.1 - 1.6e-15 56.6 0.0 2.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI40175.1 - 1.7e-15 57.1 0.0 1.3e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI40175.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI40175.1 - 4.2e-10 39.7 0.0 1.4e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI40175.1 - 9.2e-06 25.1 0.1 3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KPI40175.1 - 2.6e-05 23.6 0.0 0.0004 19.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI40175.1 - 0.00027 21.0 0.4 0.017 15.1 0.0 2.8 2 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPI40175.1 - 0.024 13.9 0.3 0.045 13.0 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KPI40175.1 - 0.036 12.8 0.3 0.29 9.8 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein Glu_dehyd_C PF16912.5 KPI40175.1 - 0.046 13.2 0.0 1.3 8.5 0.0 2.4 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KPI40175.1 - 0.12 11.4 0.1 0.31 10.1 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.21 KPI40176.1 - 8.5e-66 222.1 0.0 9.7e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 KPI40177.1 - 3e-73 247.2 15.5 3.4e-73 247.0 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40177.1 - 3e-16 59.3 17.1 3e-16 59.3 17.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI40177.1 - 0.52 9.1 15.9 1.4 7.7 3.8 2.5 2 0 0 2 2 2 0 MFS_1 like family E1-E2_ATPase PF00122.20 KPI40178.1 - 2.6e-48 163.9 0.1 3e-47 160.5 0.0 2.5 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPI40178.1 - 1.1e-46 158.8 1.4 1.1e-46 158.8 1.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPI40178.1 - 9.5e-21 75.0 0.7 1.8e-19 70.8 0.7 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI40178.1 - 1.2e-17 63.3 0.1 2.5e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPI40178.1 - 7.1e-12 45.2 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPI40178.1 - 0.00016 21.5 2.6 0.0002 21.2 1.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATG22 PF11700.8 KPI40179.1 - 2e-200 666.4 13.0 2.3e-200 666.3 13.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KPI40179.1 - 0.021 13.8 59.0 0.21 10.5 8.6 3.1 2 1 1 3 3 3 0 Major Facilitator Superfamily Fungal_trans PF04082.18 KPI40180.1 - 3.2e-18 65.7 0.3 4.8e-18 65.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI40180.1 - 1e-07 31.9 8.2 1.8e-07 31.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KPI40180.1 - 0.26 11.8 5.7 0.66 10.5 5.7 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Hexokinase_1 PF00349.21 KPI40181.1 - 2.9e-72 242.7 0.0 6.3e-72 241.7 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.16 KPI40181.1 - 7e-71 238.4 0.0 1.1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NAD_binding_10 PF13460.6 KPI40182.1 - 1.1e-21 77.5 0.0 1.4e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI40182.1 - 1.9e-05 24.9 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI40182.1 - 0.00029 20.4 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPI40182.1 - 0.00053 19.6 0.0 0.00098 18.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family CheZ PF04344.13 KPI40183.1 - 0.04 13.8 0.1 0.18 11.7 0.1 2.1 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ Fungal_trans_2 PF11951.8 KPI40184.1 - 8.8e-14 51.1 0.4 1.6e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_25 PF13649.6 KPI40185.1 - 4.9e-08 33.6 0.0 9.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40185.1 - 6.9e-07 29.2 0.0 2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40185.1 - 1.7e-06 28.5 0.0 3.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI40185.1 - 7.5e-06 26.6 0.0 1.7e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI40185.1 - 5.8e-05 23.0 0.0 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPI40185.1 - 0.11 12.6 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KPI40185.1 - 0.15 11.4 0.0 0.44 9.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glutaminase PF04960.15 KPI40186.1 - 1.8e-111 371.9 0.9 2.2e-111 371.6 0.9 1.1 1 0 0 1 1 1 1 Glutaminase STAS PF01740.21 KPI40186.1 - 0.1 12.3 0.0 1.1 8.9 0.0 2.3 1 1 0 1 1 1 0 STAS domain Meth_synt_2 PF01717.18 KPI40187.1 - 2.9e-07 30.1 0.0 7.8e-06 25.4 0.0 2.2 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPI40187.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain RRM_1 PF00076.22 KPI40188.1 - 2e-35 120.4 0.2 2.8e-13 49.5 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI40188.1 - 1.1e-10 41.2 0.0 0.029 14.2 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM PF10378.9 KPI40188.1 - 1.1e-07 31.4 8.3 1.1e-07 31.4 8.3 3.0 3 1 0 3 3 3 1 Putative RRM domain RRM_7 PF16367.5 KPI40188.1 - 4.5e-07 29.9 0.0 0.0028 17.7 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif DUF4523 PF15023.6 KPI40188.1 - 5.6e-05 23.0 0.0 0.89 9.4 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 KPI40188.1 - 0.00026 21.0 0.0 0.4 10.8 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif Peptidase_M9 PF01752.17 KPI40188.1 - 0.029 13.7 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Collagenase Nup35_RRM_2 PF14605.6 KPI40188.1 - 0.031 14.3 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KPI40188.1 - 0.071 12.9 0.0 1.1 9.1 0.0 2.4 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF4651 PF15513.6 KPI40188.1 - 0.093 12.6 0.0 22 5.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RNA_pol_3_Rpc31 PF11705.8 KPI40190.1 - 2.4e-43 149.0 11.7 3.1e-43 148.6 11.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Oxidored_FMN PF00724.20 KPI40191.1 - 2e-78 264.1 0.0 2.3e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.19 KPI40192.1 - 1.1e-52 179.5 0.2 6.9e-26 91.3 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI40192.1 - 0.054 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase APG12 PF04110.13 KPI40193.1 - 1.7e-25 89.3 0.0 3.1e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 STIMATE PF12400.8 KPI40194.1 - 8.3e-40 136.2 3.4 1.9e-39 135.1 3.4 1.6 2 0 0 2 2 2 1 STIMATE family DUF3328 PF11807.8 KPI40195.1 - 3.8e-16 59.5 0.0 6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NUDE_C PF04880.13 KPI40195.1 - 0.13 12.8 0.4 0.18 12.2 0.4 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Mito_carr PF00153.27 KPI40196.1 - 9.5e-17 60.7 0.2 1e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial carrier protein Totivirus_coat PF05518.11 KPI40197.1 - 3.1 5.7 10.6 4.8 5.1 10.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein LSM PF01423.22 KPI40198.1 - 2.3e-16 59.3 0.0 2.9e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KPI40198.1 - 3.1e-05 24.0 0.1 4.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 KPI40198.1 - 0.09 13.4 6.2 0.17 12.6 6.2 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG MFS_1 PF07690.16 KPI40199.1 - 4e-41 141.1 45.6 4e-41 141.1 45.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40199.1 - 3.2e-16 59.2 29.2 2.2e-15 56.5 14.9 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 KPI40200.1 - 1.2e-07 31.0 0.0 2.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleopor_Nup85 PF07575.13 KPI40201.1 - 0.15 10.6 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Aldo_ket_red PF00248.21 KPI40203.1 - 1.5e-65 221.4 0.0 1.7e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Prok-RING_2 PF14445.6 KPI40204.1 - 0.003 17.7 2.1 0.006 16.7 2.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 2 Phospho_p8 PF10195.9 KPI40204.1 - 0.091 13.3 2.6 0.23 12.0 2.6 1.6 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 C1_2 PF03107.16 KPI40204.1 - 0.1 13.0 5.4 0.17 12.2 5.4 1.4 1 0 0 1 1 1 0 C1 domain SDA1 PF05285.12 KPI40204.1 - 0.1 12.0 7.8 0.22 10.9 7.8 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KPI40204.1 - 1.4 7.2 8.2 2.2 6.5 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2011 PF09428.10 KPI40205.1 - 9.5e-14 51.4 0.0 3e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) DUSP PF06337.12 KPI40206.1 - 1.5e-13 51.2 0.0 1.4e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 DUSP domain zf-met PF12874.7 KPI40207.1 - 0.052 13.9 5.6 0.3 11.6 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KPI40207.1 - 0.059 13.0 0.1 0.18 11.4 0.1 1.9 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KPI40207.1 - 2.9 8.3 6.3 4.6 7.7 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KPI40207.1 - 4.8 8.3 14.2 3.1 8.9 0.5 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CCHC_2 PF13696.6 KPI40207.1 - 4.9 7.1 5.8 22 5.0 1.5 2.6 2 0 0 2 2 2 0 Zinc knuckle HEAT_EZ PF13513.6 KPI40208.1 - 3.8e-22 78.4 6.7 5.7e-08 33.1 0.1 9.0 8 1 1 9 9 9 4 HEAT-like repeat HEAT PF02985.22 KPI40208.1 - 1.3e-17 62.4 10.1 0.0024 18.0 0.1 8.7 9 0 0 9 9 8 3 HEAT repeat HEAT_2 PF13646.6 KPI40208.1 - 1.6e-13 50.8 10.1 0.0077 16.6 0.3 7.4 6 2 2 8 8 8 3 HEAT repeats IBN_N PF03810.19 KPI40208.1 - 2.6e-10 40.1 6.1 3.2e-07 30.1 1.2 4.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KPI40208.1 - 1.6e-09 38.2 1.0 4.6 7.9 0.0 6.5 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KPI40208.1 - 3.2e-08 33.4 0.9 0.035 13.7 0.0 4.6 4 1 1 5 5 5 2 CLASP N terminal RIX1 PF08167.12 KPI40208.1 - 2.6e-07 30.6 0.0 0.88 9.3 0.0 5.4 3 3 3 6 6 6 2 rRNA processing/ribosome biogenesis Arm PF00514.23 KPI40208.1 - 3.7e-07 29.9 5.5 1 9.5 0.1 5.8 7 0 0 7 7 5 2 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KPI40208.1 - 9.2e-07 28.3 9.6 0.095 11.8 0.2 5.2 4 1 1 5 5 5 3 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 KPI40208.1 - 2.9e-06 27.0 0.1 0.43 10.1 0.0 5.3 5 1 1 6 6 6 1 Tti2 family Cohesin_HEAT PF12765.7 KPI40208.1 - 6.8e-06 26.3 0.7 0.0022 18.2 0.1 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 KPI40208.1 - 8.3e-06 26.0 2.6 1.5 9.0 0.0 5.4 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KPI40208.1 - 9.1e-05 21.2 4.5 1.1 7.7 0.1 4.6 4 1 1 6 6 6 2 Adaptin N terminal region Cnd1 PF12717.7 KPI40208.1 - 0.0001 22.4 12.9 0.086 12.9 0.1 5.3 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF2608 PF11019.8 KPI40208.1 - 0.0046 16.5 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) API5 PF05918.11 KPI40208.1 - 0.022 13.6 1.7 0.14 10.9 0.1 2.6 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) MMS19_C PF12460.8 KPI40208.1 - 0.026 13.7 8.2 0.11 11.6 0.1 4.3 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal CbeA_antitoxin PF06154.11 KPI40208.1 - 0.094 13.3 0.4 1.8 9.2 0.0 3.1 3 1 0 3 3 3 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A UPF0253 PF06786.12 KPI40208.1 - 0.097 13.0 0.5 2.9 8.2 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0253) DUF4042 PF13251.6 KPI40208.1 - 0.34 10.6 4.8 11 5.6 0.1 4.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) Amino_oxidase PF01593.24 KPI40209.1 - 1.8e-21 77.0 0.0 2e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI40209.1 - 5.8e-16 58.5 0.1 8.6e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI40209.1 - 3.3e-08 33.0 1.5 4.8e-08 32.5 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KPI40209.1 - 2.3e-07 31.3 0.2 4.4e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI40209.1 - 9.6e-07 28.3 0.1 1.5e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40209.1 - 1.3e-06 28.2 1.0 1.3e-06 28.2 1.0 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPI40209.1 - 1.6e-06 27.8 0.3 1.8e-06 27.6 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI40209.1 - 2.2e-06 26.7 1.1 3.3e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KPI40209.1 - 7.6e-06 25.3 0.2 1.1e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KPI40209.1 - 3.9e-05 23.1 0.6 5.9e-05 22.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPI40209.1 - 0.00025 20.4 0.1 0.00025 20.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KPI40209.1 - 0.00063 18.9 0.5 0.00082 18.6 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI40209.1 - 0.0013 18.1 0.2 0.002 17.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI40209.1 - 0.0073 16.3 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI40209.1 - 0.0094 15.0 0.3 0.013 14.6 0.3 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein MCRA PF06100.11 KPI40209.1 - 0.015 14.1 0.1 0.015 14.1 0.1 1.1 1 0 0 1 1 1 0 MCRA family TrkA_N PF02254.18 KPI40209.1 - 0.021 15.1 0.2 0.032 14.5 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF1188 PF06690.11 KPI40209.1 - 0.058 12.9 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Glu_dehyd_C PF16912.5 KPI40209.1 - 0.064 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KPI40211.1 - 5.5e-29 101.5 0.0 1.5e-28 100.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPI40211.1 - 1.2e-06 28.6 0.4 0.031 14.2 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI40211.1 - 7.9e-05 22.0 0.1 0.00042 19.6 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40211.1 - 0.00012 21.8 0.0 0.082 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI40211.1 - 0.00088 19.5 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI40211.1 - 0.022 13.8 0.4 0.87 8.6 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 KPI40211.1 - 0.062 13.9 0.4 19 5.9 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI40211.1 - 0.065 12.1 0.1 19 4.0 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase SNF2_N PF00176.23 KPI40212.1 - 1.4e-13 50.3 0.2 2.7e-08 33.0 0.1 2.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KPI40212.1 - 2.3e-10 40.3 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase CN_hydrolase PF00795.22 KPI40212.1 - 0.045 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase zf-RING_UBOX PF13445.6 KPI40212.1 - 0.064 13.3 10.1 1.2 9.2 2.4 2.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 KPI40212.1 - 0.15 12.0 16.7 2.2 8.3 1.5 2.8 2 0 0 2 2 2 0 zinc-RING finger domain FYVE PF01363.21 KPI40212.1 - 2.3 8.4 7.6 15 5.8 0.0 2.8 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.6 KPI40212.1 - 2.5 8.0 15.1 0.38 10.6 6.8 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KPI40212.1 - 7.6 6.5 10.0 9.8 6.1 1.0 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 KPI40213.1 - 3.3e-22 78.9 55.5 8.3e-18 64.4 43.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40213.1 - 1.4 7.7 33.7 0.22 10.3 5.2 3.4 3 0 0 3 3 3 0 Sugar (and other) transporter NPC1_N PF16414.5 KPI40214.1 - 3.1e-84 282.4 8.1 4.3e-84 281.9 8.1 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KPI40214.1 - 5.5e-73 246.4 12.6 2.5e-72 244.2 12.6 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KPI40214.1 - 5e-51 172.6 6.7 5e-51 172.6 6.7 3.4 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KPI40214.1 - 6.1e-05 22.1 8.5 6.1e-05 22.1 8.5 2.9 2 1 0 2 2 2 1 MMPL family Folate_rec PF03024.14 KPI40214.1 - 0.027 14.3 3.4 0.054 13.4 3.4 1.5 1 0 0 1 1 1 0 Folate receptor family ACR_tran PF00873.19 KPI40214.1 - 0.3 8.7 16.8 0.0059 14.3 8.1 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family PhoLip_ATPase_C PF16212.5 KPI40216.1 - 9.2e-82 274.5 19.3 9.2e-82 274.5 19.3 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KPI40216.1 - 2.1e-27 94.6 2.3 5.2e-27 93.3 1.0 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KPI40216.1 - 1.9e-13 50.3 0.0 7.2e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPI40216.1 - 1.1e-09 39.0 3.0 3.3e-05 24.3 0.5 3.4 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPI40216.1 - 2e-08 34.0 0.0 2e-08 34.0 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KPI40216.1 - 0.0065 16.2 0.1 0.024 14.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nup88 PF10168.9 KPI40218.1 - 0.0001 20.3 1.1 0.039 11.8 1.3 2.9 2 1 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 KPI40218.1 - 0.0022 18.1 6.8 0.0051 16.9 6.8 1.7 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 CREPT PF16566.5 KPI40218.1 - 0.1 12.8 1.8 0.35 11.0 1.8 1.9 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Snapin_Pallidin PF14712.6 KPI40218.1 - 3.4 8.1 10.0 29 5.2 0.6 4.2 4 0 0 4 4 4 0 Snapin/Pallidin V_ATPase_I PF01496.19 KPI40218.1 - 6.8 4.5 6.7 9.5 4.0 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ThiJ_like PF17124.5 KPI40219.1 - 1.4e-59 201.1 0.0 1.6e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KPI40219.1 - 2.9e-10 40.2 0.0 5.4e-09 36.1 0.0 2.7 1 1 0 1 1 1 1 DJ-1/PfpI family DUF3295 PF11702.8 KPI40220.1 - 6.5e-109 365.5 40.4 7.5e-109 365.3 40.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KPI40220.1 - 8.9e-12 44.6 2.5 1.9e-11 43.6 2.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DNA_pol_phi PF04931.13 KPI40220.1 - 2 6.4 8.1 3.5 5.6 8.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S16 PF00886.19 KPI40221.1 - 1e-21 76.8 0.0 1.8e-21 76.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.22 KPI40222.1 - 7.3e-33 112.2 0.3 2e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI40222.1 - 3.4e-12 46.3 0.1 9.6e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif DUF4175 PF13779.6 KPI40222.1 - 0.094 10.6 31.3 0.15 9.9 31.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RRM_3 PF08777.11 KPI40222.1 - 0.13 12.3 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif GEMIN8 PF15348.6 KPI40222.1 - 3.3 7.9 7.9 13 6.0 3.9 2.5 2 1 1 3 3 3 0 Gemini of Cajal bodies-associated protein 8 Sdh5 PF03937.16 KPI40223.1 - 2.5e-23 81.8 0.8 1.5e-22 79.3 0.5 2.0 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase HAV_VP PF12944.7 KPI40224.1 - 0.05 13.6 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP DEAD PF00270.29 KPI40225.1 - 1.2e-41 142.4 0.0 2.2e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI40225.1 - 3.8e-29 101.3 0.0 8.9e-29 100.1 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI40225.1 - 6.6e-05 23.0 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KPI40225.1 - 0.0015 17.4 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KPI40225.1 - 0.018 14.7 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase LSDAT_prok PF18171.1 KPI40225.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote BTB PF00651.31 KPI40226.1 - 3e-10 40.3 0.0 1.3e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain NmrA PF05368.13 KPI40227.1 - 3.4e-28 98.8 0.1 1.6e-27 96.6 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI40227.1 - 8.7e-12 45.3 0.5 1.3e-11 44.7 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KPI40227.1 - 0.014 14.8 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Inp1 PF12634.7 KPI40228.1 - 9.2e-42 142.3 0.1 6.6e-41 139.5 0.0 2.4 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 F-box-like PF12937.7 KPI40229.1 - 3.7e-06 26.7 1.0 0.12 12.2 0.3 3.3 2 2 0 2 2 2 2 F-box-like F-box PF00646.33 KPI40229.1 - 0.0094 15.8 2.4 1.2 9.0 0.1 3.4 3 0 0 3 3 3 2 F-box domain DUF3420 PF11900.8 KPI40229.1 - 0.37 11.0 2.4 36 4.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3420) HET PF06985.11 KPI40231.1 - 9.5e-25 87.7 0.6 2.2e-24 86.5 0.6 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 KPI40232.1 - 1.1e-48 165.9 0.2 1.4e-48 165.5 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI40232.1 - 1.2e-15 57.9 0.1 1.7e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KPI40232.1 - 0.00072 18.6 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 KPI40233.1 - 5.6e-13 48.5 54.4 2.8e-08 33.1 41.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5345 PF17280.2 KPI40233.1 - 8.1 6.5 7.4 4.7 7.3 0.4 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Abhydrolase_1 PF00561.20 KPI40234.1 - 4.3e-19 69.2 0.2 1.4e-18 67.5 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI40234.1 - 9.1e-19 68.9 0.0 1.1e-18 68.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI40234.1 - 1.7e-13 50.4 0.2 4.1e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KPI40234.1 - 9e-05 22.1 0.4 0.0015 18.1 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1057 PF06342.12 KPI40234.1 - 0.00016 20.8 0.3 0.00073 18.7 0.0 2.0 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 KPI40234.1 - 0.00022 20.3 0.1 0.00037 19.5 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 KPI40234.1 - 0.00085 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KPI40234.1 - 0.0012 18.4 0.0 0.015 14.8 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KPI40234.1 - 0.0019 17.3 0.1 0.0057 15.7 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase DUF676 PF05057.14 KPI40234.1 - 0.0081 15.7 0.0 0.02 14.4 0.0 1.7 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 KPI40234.1 - 0.0097 16.0 0.3 0.062 13.4 0.3 2.0 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KPI40234.1 - 0.045 13.6 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.18 KPI40234.1 - 0.1 12.2 0.0 0.82 9.2 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 KPI40234.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF4286 PF14114.6 KPI40235.1 - 0.068 13.7 0.0 3.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Helo_like_N PF17111.5 KPI40236.1 - 1.3e-06 28.0 0.2 2.1e-06 27.2 0.2 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_4 PF13637.6 KPI40236.1 - 0.00025 21.5 0.1 0.038 14.6 0.0 2.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI40236.1 - 0.00085 19.9 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI40236.1 - 0.0014 18.9 0.0 0.0066 16.7 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) HeLo PF14479.6 KPI40236.1 - 0.0014 18.5 0.5 0.0032 17.3 0.5 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank PF00023.30 KPI40236.1 - 0.0072 16.7 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat DUF489 PF04356.12 KPI40236.1 - 0.0097 15.9 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF489) adh_short PF00106.25 KPI40237.1 - 1.6e-26 93.0 0.0 2.3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40237.1 - 1.6e-12 47.5 0.0 3.1e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40237.1 - 0.00028 20.9 0.0 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPI40237.1 - 0.0071 15.8 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI40237.1 - 0.23 10.8 0.1 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ecm33 PF12454.8 KPI40238.1 - 0.083 13.0 1.0 17 5.6 0.2 3.3 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Sugar_tr PF00083.24 KPI40239.1 - 5.1e-78 263.0 30.1 5.8e-78 262.8 30.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40239.1 - 4.4e-22 78.5 45.5 8.1e-16 57.9 18.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily FixQ PF05545.11 KPI40239.1 - 0.074 13.0 0.3 0.074 13.0 0.3 2.7 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1648 PF07853.11 KPI40239.1 - 1.3 8.7 5.2 0.7 9.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Deltameth_res PF16020.5 KPI40239.1 - 2.3 8.2 7.9 3.2 7.7 0.3 4.2 4 0 0 4 4 4 0 Deltamethrin resistance Clat_adaptor_s PF01217.20 KPI40240.1 - 2.3e-50 170.2 4.7 2.7e-49 166.8 4.7 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DEAD PF00270.29 KPI40242.1 - 9.6e-35 119.9 0.0 2.1e-33 115.5 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KPI40242.1 - 2.8e-21 75.5 0.0 5.1e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KPI40242.1 - 2.5e-20 72.9 0.0 1.4e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI40242.1 - 0.00045 20.3 0.0 0.0021 18.1 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Sugar_tr PF00083.24 KPI40243.1 - 4.4e-65 220.3 26.6 1.1e-42 146.5 1.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1365 PF07103.11 KPI40243.1 - 1.2e-63 215.0 0.1 1.9e-63 214.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MFS_1 PF07690.16 KPI40243.1 - 1.9e-22 79.7 39.7 3.5e-16 59.1 11.1 2.6 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3377 PF11857.8 KPI40243.1 - 0.01 15.8 0.5 3.8 7.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3377) LAX PF15681.5 KPI40243.1 - 0.13 11.0 0.1 0.24 10.2 0.1 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X ABC_tran PF00005.27 KPI40246.1 - 5.5e-51 172.7 0.4 5.7e-25 88.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KPI40246.1 - 1.2e-44 152.2 44.3 8.2e-24 84.2 20.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 KPI40246.1 - 5.9e-12 46.0 2.8 0.0032 17.3 0.1 3.9 5 0 0 5 5 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KPI40246.1 - 9e-11 42.0 0.7 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KPI40246.1 - 1e-10 41.4 1.8 2.1e-05 24.1 0.1 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPI40246.1 - 1.4e-09 38.8 0.0 0.0012 19.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPI40246.1 - 1.6e-09 38.4 0.2 0.0018 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KPI40246.1 - 3.2e-09 36.4 1.4 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPI40246.1 - 1.9e-07 31.5 0.1 0.041 14.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 KPI40246.1 - 2e-06 27.9 0.1 0.02 14.8 0.0 3.1 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KPI40246.1 - 5e-06 26.2 0.1 0.16 11.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KPI40246.1 - 5.4e-06 26.8 0.1 0.27 11.6 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_28 PF13521.6 KPI40246.1 - 7.7e-06 26.2 0.2 0.16 12.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KPI40246.1 - 1.8e-05 24.7 0.1 0.21 11.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KPI40246.1 - 4e-05 23.7 3.7 0.06 13.4 0.5 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 KPI40246.1 - 7.1e-05 22.5 1.4 0.063 12.9 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPI40246.1 - 0.00012 21.9 0.3 0.33 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KPI40246.1 - 0.0003 21.2 0.4 1.7 9.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KPI40246.1 - 0.00032 21.2 0.0 0.31 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KPI40246.1 - 0.0011 18.3 0.5 0.94 8.6 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KPI40246.1 - 0.0011 19.0 0.5 1.3 9.0 0.1 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KPI40246.1 - 0.0014 17.8 0.5 0.62 9.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 KPI40246.1 - 0.0019 17.9 0.8 1 9.0 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KPI40246.1 - 0.0024 17.2 0.1 0.62 9.3 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 KPI40246.1 - 0.0025 16.9 0.9 1.9 7.5 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Roc PF08477.13 KPI40246.1 - 0.0032 17.7 0.4 2.7 8.3 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KPI40246.1 - 0.0032 17.6 0.2 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KPI40246.1 - 0.0037 16.7 0.2 0.49 9.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.6 KPI40246.1 - 0.0053 16.5 0.1 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KPI40246.1 - 0.0057 16.3 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KPI40246.1 - 0.0059 16.7 1.6 1.4 8.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin family Cytidylate_kin PF02224.18 KPI40246.1 - 0.0072 16.1 0.6 0.37 10.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase PRK PF00485.18 KPI40246.1 - 0.0074 16.0 1.2 1.7 8.3 0.2 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_35 PF14516.6 KPI40246.1 - 0.0093 14.8 0.2 0.76 8.5 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain ABC_ATPase PF09818.9 KPI40246.1 - 0.011 14.6 0.2 0.82 8.4 0.0 2.4 3 0 0 3 3 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KPI40246.1 - 0.012 15.4 0.7 5.1 6.8 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KPI40246.1 - 0.014 15.3 0.9 10 6.0 0.1 3.3 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 KPI40246.1 - 0.018 15.4 0.6 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KPI40246.1 - 0.029 13.6 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DnaB_C PF03796.15 KPI40246.1 - 0.041 13.2 0.1 9.2 5.5 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain KAP_NTPase PF07693.14 KPI40246.1 - 0.047 12.9 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 KPI40246.1 - 0.061 12.8 1.1 8.1 5.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KPI40246.1 - 0.07 12.9 0.8 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.18 KPI40246.1 - 0.072 12.9 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein PIF1 PF05970.14 KPI40246.1 - 0.077 12.1 0.1 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 KPI40246.1 - 0.11 11.9 0.1 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.9 KPI40246.1 - 0.12 12.2 0.6 7 6.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 KPI40246.1 - 0.12 12.1 0.4 5 6.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KPI40246.1 - 0.17 11.3 0.4 11 5.4 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KPI40246.1 - 0.18 11.9 0.1 26 4.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KPI40246.1 - 0.19 11.6 0.5 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B dNK PF01712.19 KPI40246.1 - 0.19 11.5 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Gtr1_RagA PF04670.12 KPI40246.1 - 0.26 10.6 0.8 19 4.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region APS_kinase PF01583.20 KPI40246.1 - 0.27 11.1 1.2 8.9 6.2 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase SRP54 PF00448.22 KPI40246.1 - 0.6 9.7 2.6 3.2 7.3 0.3 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KPI40246.1 - 0.63 8.6 1.2 3.3 6.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KPI40246.1 - 0.9 8.6 34.1 1.4 8.0 11.3 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein Glyco_hydro_31 PF01055.26 KPI40247.1 - 1.8e-90 304.3 0.0 2.3e-90 303.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPI40247.1 - 1.5e-12 47.6 0.1 7.2e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like F-box-like PF12937.7 KPI40249.1 - 0.04 13.8 0.3 0.12 12.2 0.3 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KPI40249.1 - 0.46 11.0 1.6 12 6.4 0.3 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF2237 PF09996.9 KPI40250.1 - 6.1e-18 64.9 0.0 2.2e-17 63.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) adh_short PF00106.25 KPI40251.1 - 8e-24 84.2 0.1 1.1e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40251.1 - 3.7e-18 66.0 0.0 5.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40251.1 - 1.5e-09 38.0 0.1 2.2e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI40251.1 - 0.03 13.4 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 KPI40251.1 - 0.062 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LDcluster4 PF18306.1 KPI40251.1 - 0.095 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster4 family Epimerase PF01370.21 KPI40251.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PAC2 PF09754.9 KPI40251.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.7 1 1 1 2 2 2 0 PAC2 family Ovate PF04844.13 KPI40252.1 - 0.062 13.3 0.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Transcriptional repressor, ovate ATF7IP_BD PF16788.5 KPI40252.1 - 0.078 13.1 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 ATF-interacting protein binding domain adh_short PF00106.25 KPI40253.1 - 7.7e-11 41.8 0.0 1.5e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40253.1 - 3.9e-10 39.7 0.1 5.1e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KPI40253.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 KPI40253.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KPI40253.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPI40253.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 KPI40255.1 - 7e-36 123.9 27.1 7e-36 123.9 27.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5337 PF17272.2 KPI40255.1 - 0.72 9.7 4.3 6.2 6.7 0.2 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5337) MFS_1 PF07690.16 KPI40256.1 - 6.3e-26 91.1 60.0 3e-18 65.9 24.9 3.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI40256.1 - 0.00011 21.2 9.6 0.00024 20.1 9.6 1.5 1 0 0 1 1 1 1 MFS_1 like family IRF-2BP1_2 PF11261.8 KPI40257.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger DUF5082 PF16888.5 KPI40257.1 - 0.18 12.1 14.6 0.46 10.8 11.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) ERM PF00769.19 KPI40257.1 - 0.65 9.8 29.9 0.18 11.6 16.0 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family RNA_pol_Rpb2_5 PF04567.17 KPI40257.1 - 1.7 9.3 4.3 9.9 6.8 4.3 2.5 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Spore_III_AB PF09548.10 KPI40257.1 - 2.1 8.4 11.9 1.1 9.3 7.6 2.2 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Cauli_AT PF03233.13 KPI40257.1 - 2.2 8.2 10.1 1.8 8.5 7.7 2.0 1 1 0 2 2 2 0 Aphid transmission protein TPR_MLP1_2 PF07926.12 KPI40257.1 - 9.9 6.2 28.3 5.4 7.1 21.3 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AMP-binding PF00501.28 KPI40258.1 - 6.1e-94 315.0 0.0 7.3e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI40258.1 - 6.7e-12 46.2 0.0 1.9e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PALP PF00291.25 KPI40259.1 - 1.2e-61 208.7 0.1 1.9e-61 208.1 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Dpy19 PF10034.9 KPI40259.1 - 0.14 10.4 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Chitin_synth_1 PF01644.17 KPI40260.1 - 5.8e-70 234.5 0.0 8.5e-70 233.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KPI40260.1 - 1.3e-28 98.7 0.0 2.6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPI40260.1 - 1.3e-25 90.0 2.6 1.8e-19 69.8 0.0 2.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPI40260.1 - 1.1e-09 38.5 0.2 1.1e-09 38.5 0.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 LUC7 PF03194.15 KPI40262.1 - 4.5e-06 26.5 0.1 7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 LUC7 N_terminus zf-C2H2_4 PF13894.6 KPI40262.1 - 4.2e-05 24.0 11.0 0.038 14.8 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI40262.1 - 0.00014 22.1 10.8 0.042 14.3 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Spc7 PF08317.11 KPI40262.1 - 0.00045 19.2 10.8 0.00066 18.6 10.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-H2C2_2 PF13465.6 KPI40262.1 - 0.0028 18.0 8.9 0.028 14.8 0.6 2.7 3 0 0 3 3 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KPI40262.1 - 0.0059 16.9 3.5 0.01 16.1 3.5 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KPI40262.1 - 0.01 16.1 2.7 0.023 15.0 0.4 2.2 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF883 PF05957.13 KPI40262.1 - 0.014 16.0 1.5 0.03 14.9 1.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) zf-met PF12874.7 KPI40262.1 - 0.016 15.6 3.5 0.16 12.4 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GAS PF13851.6 KPI40262.1 - 0.02 14.3 13.0 0.033 13.5 13.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Zn-ribbon_8 PF09723.10 KPI40262.1 - 0.026 14.6 3.2 0.18 11.9 1.9 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Cdh1_DBD_1 PF18196.1 KPI40262.1 - 0.074 13.4 0.6 0.15 12.4 0.5 1.5 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 ADIP PF11559.8 KPI40262.1 - 0.12 12.4 14.8 0.23 11.6 12.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 KPI40262.1 - 0.17 12.1 7.7 0.43 10.8 7.7 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cep57_MT_bd PF06657.13 KPI40262.1 - 0.18 12.3 5.6 0.086 13.3 1.7 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uso1_p115_C PF04871.13 KPI40262.1 - 0.18 12.1 11.4 0.41 11.0 11.4 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 KPI40262.1 - 0.19 12.3 16.4 1.4 9.4 4.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 KPI40262.1 - 0.25 10.8 7.3 0.36 10.2 7.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Paralemmin PF03285.15 KPI40262.1 - 0.25 10.9 1.5 0.58 9.7 1.5 1.6 1 0 0 1 1 1 0 Paralemmin TMF_TATA_bd PF12325.8 KPI40262.1 - 0.41 10.9 9.0 2.2 8.5 9.0 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AKNA PF12443.8 KPI40262.1 - 0.44 11.2 8.5 0.22 12.2 0.8 2.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor Spc24 PF08286.11 KPI40262.1 - 0.53 10.6 11.0 0.15 12.3 2.8 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 KPI40262.1 - 0.58 11.1 9.6 1.8 9.5 9.7 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 KPI40262.1 - 0.64 10.5 2.3 10 6.6 0.0 2.6 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KPI40262.1 - 0.65 8.5 5.3 0.91 8.1 5.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dad3 PF08656.10 KPI40262.1 - 0.71 10.0 3.9 0.21 11.7 0.9 1.7 2 0 0 2 2 1 0 DASH complex subunit Dad3 YabA PF06156.13 KPI40262.1 - 0.71 10.5 7.0 4.9 7.9 1.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA GIT_CC PF16559.5 KPI40262.1 - 0.86 9.5 11.0 0.21 11.5 2.4 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 PF16888.5 KPI40262.1 - 1.1 9.6 11.8 5.4 7.3 11.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) GrpE PF01025.19 KPI40262.1 - 1.2 8.8 11.0 4.9 6.8 10.1 2.3 2 1 0 2 2 2 0 GrpE CENP-F_leu_zip PF10473.9 KPI40262.1 - 1.4 8.9 10.1 3.7 7.6 10.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 KPI40262.1 - 1.6 6.5 5.0 2.2 6.1 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_ribbon_SprT PF17283.2 KPI40262.1 - 1.8 8.6 4.4 3.4 7.7 4.4 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain LMBR1 PF04791.16 KPI40262.1 - 1.8 7.4 3.2 2.3 7.0 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4795 PF16043.5 KPI40262.1 - 1.8 8.1 7.7 0.45 10.1 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DivIC PF04977.15 KPI40262.1 - 1.8 8.4 16.4 0.19 11.5 4.8 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4618 PF15397.6 KPI40262.1 - 1.8 7.9 9.0 5 6.5 9.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) zf-C2H2_6 PF13912.6 KPI40262.1 - 1.9 8.6 10.0 0.17 11.9 1.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KPI40262.1 - 2.2 8.4 6.6 15 5.7 1.1 2.3 2 0 0 2 2 2 0 BED zinc finger FUSC PF04632.12 KPI40262.1 - 2.6 6.5 7.4 4.1 5.8 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KPI40262.1 - 2.8 7.5 7.9 5.2 6.6 7.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpecificRecomb PF10136.9 KPI40262.1 - 3.5 5.8 5.9 4.3 5.5 5.9 1.0 1 0 0 1 1 1 0 Site-specific recombinase DUF4407 PF14362.6 KPI40262.1 - 3.8 6.8 9.2 6.1 6.1 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 KPI40262.1 - 3.8 7.8 12.2 0.56 10.5 1.3 3.3 2 2 1 3 3 3 0 Homeobox associated leucine zipper Snf7 PF03357.21 KPI40262.1 - 3.9 7.0 10.6 6.4 6.3 10.6 1.2 1 0 0 1 1 1 0 Snf7 Ax_dynein_light PF10211.9 KPI40262.1 - 4 7.3 10.6 26 4.7 10.5 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain WXG100 PF06013.12 KPI40262.1 - 4.8 7.5 8.7 1.8 8.9 0.7 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 KPI40262.1 - 5.6 7.2 9.5 55 4.0 9.5 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 KPI40262.1 - 5.7 7.3 16.0 9.2 6.6 16.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 KPI40262.1 - 5.8 7.3 9.0 30 5.0 6.9 2.5 2 1 0 2 2 1 0 Tup N-terminal Cnn_1N PF07989.11 KPI40262.1 - 7.1 6.9 9.6 8.2 6.7 1.8 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 KPI40262.1 - 7.5 6.6 12.4 12 5.9 12.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CLZ PF16526.5 KPI40262.1 - 8 6.9 7.9 2.8 8.4 1.4 2.3 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_Maf PF03131.17 KPI40262.1 - 9.2 6.9 12.3 10 6.7 2.4 2.6 1 1 0 2 2 2 0 bZIP Maf transcription factor MFS_1 PF07690.16 KPI40263.1 - 1.7e-40 139.1 34.6 1.7e-40 139.1 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPI40263.1 - 0.0022 16.4 12.3 0.015 13.6 0.5 3.6 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family VIT1 PF01988.19 KPI40263.1 - 0.009 15.9 3.4 0.009 15.9 3.4 2.5 3 1 0 3 3 3 1 VIT family MRP-S28 PF10213.9 KPI40264.1 - 3.3e-39 134.2 0.1 6.6e-39 133.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Uds1 PF15456.6 KPI40265.1 - 0.031 14.4 0.4 0.067 13.4 0.4 1.5 1 0 0 1 1 1 0 Up-regulated During Septation RNase_J_C PF17770.1 KPI40265.1 - 0.21 12.7 0.4 2.5 9.2 0.0 2.7 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain zf-C2H2 PF00096.26 KPI40268.1 - 3e-08 33.7 4.9 0.0013 19.1 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 KPI40268.1 - 6.2e-07 28.7 0.3 3.4e-06 26.3 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KPI40268.1 - 6.5e-06 26.5 12.5 0.002 18.8 0.7 3.5 3 0 0 3 3 2 2 C2H2-type zinc finger GAGA PF09237.11 KPI40268.1 - 5.4e-05 22.9 3.9 0.078 12.8 0.9 2.5 1 1 1 2 2 2 2 GAGA factor zf-H2C2_2 PF13465.6 KPI40268.1 - 0.00015 22.0 0.4 0.00015 22.0 0.4 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPI40268.1 - 0.011 16.0 2.6 2 8.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KPI40268.1 - 0.015 15.6 1.2 0.015 15.6 1.2 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KPI40268.1 - 0.03 14.7 0.8 4.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Crust_neurohorm PF01147.17 KPI40268.1 - 0.09 12.6 0.6 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family zf-C2H2_6 PF13912.6 KPI40268.1 - 0.12 12.4 1.4 11 6.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KPI40268.1 - 0.23 11.5 1.4 2.2 8.3 1.4 2.3 1 1 0 1 1 1 0 BED zinc finger Zn-C2H2_12 PF18112.1 KPI40268.1 - 0.54 10.8 3.3 2 9.0 0.4 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Homeobox_KN PF05920.11 KPI40270.1 - 8.7e-06 25.5 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 KPI40270.1 - 0.00014 22.1 0.7 0.00014 22.1 0.7 4.4 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI40270.1 - 0.00017 22.1 0.6 0.00017 22.1 0.6 4.9 5 0 0 5 5 5 1 C2H2-type zinc finger zf-met PF12874.7 KPI40270.1 - 0.00035 20.9 0.2 0.39 11.2 0.0 4.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Homeodomain PF00046.29 KPI40270.1 - 0.0012 18.7 0.4 0.0012 18.7 0.4 1.9 2 0 0 2 2 2 1 Homeodomain zf-C2H2_jaz PF12171.8 KPI40270.1 - 0.011 16.0 2.2 0.062 13.6 0.0 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KPI40270.1 - 0.026 14.8 4.9 2.9 8.3 4.9 2.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KPI40270.1 - 1.1 9.8 4.4 9.9 6.7 0.0 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KPI40270.1 - 5 7.0 8.8 8.3 6.3 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KPI40270.1 - 8.1 6.3 8.2 0.72 9.7 0.5 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type NAD_binding_10 PF13460.6 KPI40271.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI40271.1 - 1.2e-05 25.0 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NESP55 PF06390.12 KPI40272.1 - 1.7 8.2 9.6 4.8 6.7 9.6 1.8 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) PhyH PF05721.13 KPI40273.1 - 2e-54 185.1 0.0 2.5e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FlhD PF05247.13 KPI40273.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 Flagellar transcriptional activator (FlhD) Pkinase PF00069.25 KPI40274.1 - 3.1e-70 236.5 0.0 4.1e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI40274.1 - 5.3e-35 120.9 0.0 9.3e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI40274.1 - 1.3e-05 24.4 0.1 1.3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KPI40274.1 - 1.6e-05 24.4 0.1 0.00038 19.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPI40274.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KPI40274.1 - 6.9e-05 22.6 0.2 0.26 10.9 0.0 3.0 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KPI40274.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KPI40274.1 - 0.0048 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family MBOAT_2 PF13813.6 KPI40275.1 - 4.3e-13 49.3 2.1 9.6e-13 48.2 2.1 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_M14 PF00246.24 KPI40275.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KPI40275.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Cation_efflux PF01545.21 KPI40276.1 - 5.7e-42 143.7 8.9 8e-42 143.2 8.9 1.2 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.16 KPI40276.1 - 0.0048 16.3 6.2 0.0048 16.3 6.2 3.0 3 0 0 3 3 3 2 High-affinity nickel-transport protein Zip PF02535.22 KPI40276.1 - 0.15 11.3 31.4 0.016 14.4 14.9 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter DUF2946 PF11162.8 KPI40276.1 - 0.66 10.6 0.0 0.66 10.6 0.0 4.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2946) GGACT PF06094.12 KPI40277.1 - 6.7e-05 23.5 0.0 0.00014 22.5 0.0 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like zf-RING_2 PF13639.6 KPI40278.1 - 6.2e-07 29.6 8.7 1.2e-06 28.8 4.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KPI40278.1 - 2.3e-06 27.8 1.7 2.3e-06 27.8 1.7 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KPI40278.1 - 0.00093 19.0 11.9 0.0047 16.7 7.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI40278.1 - 0.084 12.7 6.3 0.14 12.1 3.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.7 KPI40279.1 - 4.6e-09 37.2 0.2 6.2e-09 36.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI40279.1 - 0.0042 16.8 0.1 0.0066 16.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding PF00501.28 KPI40281.1 - 1.8e-75 254.1 4.1 2.5e-61 207.5 0.4 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KPI40281.1 - 2.8e-13 50.6 0.3 6e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EI24 PF07264.11 KPI40282.1 - 3e-12 47.1 0.0 2.5e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) XFP_N PF09364.10 KPI40283.1 - 0.23 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 XFP N-terminal domain PhyH PF05721.13 KPI40284.1 - 1.6e-09 38.3 0.0 2.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RabGAP-TBC PF00566.18 KPI40288.1 - 3.6e-48 164.1 0.0 8.5e-48 162.8 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GIT_CC PF16559.5 KPI40288.1 - 1.1 9.1 4.5 19 5.2 0.1 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor EzrA PF06160.12 KPI40288.1 - 1.6 6.8 11.2 0.82 7.8 7.6 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.8 KPI40288.1 - 1.6 8.8 18.6 1.8 8.6 9.6 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PKcGMP_CC PF16808.5 KPI40288.1 - 1.8 8.5 6.9 0.32 10.9 2.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase H-kinase_dim PF02895.14 KPI40288.1 - 1.8 9.0 4.4 14 6.2 0.4 3.2 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Spc7 PF08317.11 KPI40288.1 - 6.3 5.6 17.3 1.1 8.1 2.6 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein IlvN PF07991.12 KPI40289.1 - 5.2e-46 156.2 0.0 8.1e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KPI40289.1 - 2.4e-39 134.9 0.0 3.7e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KPI40289.1 - 0.036 14.6 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Inhibitor_I36 PF03995.13 KPI40290.1 - 0.011 15.6 1.4 0.023 14.6 1.4 1.6 1 1 0 1 1 1 0 Peptidase inhibitor family I36 HmuY PF14064.6 KPI40290.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 HmuY protein DUF4148 PF13663.6 KPI40291.1 - 1.4 9.2 4.2 2.6 8.3 3.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) adh_short PF00106.25 KPI40292.1 - 2.4e-06 27.1 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40292.1 - 0.00034 20.6 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI40292.1 - 0.0039 16.8 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_3_C PF01915.22 KPI40293.1 - 2.4e-46 158.2 0.0 4.5e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI40293.1 - 4.5e-37 128.1 0.0 7e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI40293.1 - 2e-17 63.0 0.0 4e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Methyltransf_31 PF13847.6 KPI40295.1 - 1.6e-29 102.7 0.0 2.3e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40295.1 - 2.6e-27 95.3 0.1 4.8e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI40295.1 - 2.6e-25 88.9 0.1 4.7e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI40295.1 - 3e-20 72.5 0.0 4.5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KPI40295.1 - 5.3e-18 65.6 0.1 8.2e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI40295.1 - 4.2e-17 62.5 0.0 8.2e-17 61.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain MetW PF07021.12 KPI40295.1 - 1.3e-10 41.2 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KPI40295.1 - 3.7e-09 36.6 0.1 4.9e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPI40295.1 - 5e-09 35.9 0.0 6.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPI40295.1 - 1.1e-08 34.8 0.0 4.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.11 KPI40295.1 - 7e-07 28.5 0.3 6.6e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 KPI40295.1 - 8.2e-07 27.9 0.1 1.1e-06 27.5 0.1 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 KPI40295.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPI40295.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KPI40295.1 - 3.1e-05 23.4 0.0 4.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 KPI40295.1 - 5.6e-05 22.4 0.0 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.7 KPI40295.1 - 0.0001 22.2 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KPI40295.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F NodS PF05401.11 KPI40295.1 - 0.00017 21.3 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KPI40295.1 - 0.00081 18.7 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 KPI40295.1 - 0.0011 18.8 0.7 0.018 14.7 0.6 2.6 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_PK PF05891.12 KPI40295.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 KPI40295.1 - 0.0053 16.6 0.2 0.046 13.6 0.2 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.14 KPI40295.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KPI40295.1 - 0.024 13.7 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CheR PF01739.18 KPI40295.1 - 0.049 13.1 0.1 1.1 8.7 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KPI40295.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TFIIB PF00382.19 KPI40296.1 - 7.4e-26 90.0 0.0 5.8e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KPI40296.1 - 2.3e-12 46.2 0.4 3.9e-12 45.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KPI40296.1 - 0.00055 19.7 0.1 0.00091 19.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPI40296.1 - 0.0079 16.3 0.1 0.57 10.3 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain GerE PF00196.19 KPI40296.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_ISL3 PF13542.6 KPI40296.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 F-box-like_2 PF13013.6 KPI40297.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain DEAD_2 PF06733.15 KPI40298.1 - 2.3e-57 193.5 0.2 2.3e-57 193.5 0.2 1.5 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KPI40298.1 - 5.3e-47 160.0 1.3 3.6e-42 144.2 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KPI40298.1 - 6.6e-37 127.3 0.0 4.9e-36 124.5 0.0 2.4 1 1 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KPI40298.1 - 3.8e-05 23.8 0.3 0.0087 16.1 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI40298.1 - 0.00099 18.9 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 KPI40298.1 - 0.042 12.6 0.0 0.3 9.8 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain DUF3800 PF12686.7 KPI40298.1 - 0.089 13.4 0.1 0.37 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) Transketolase_N PF00456.21 KPI40299.1 - 9.3e-119 396.3 0.1 1.3e-118 395.8 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KPI40299.1 - 1.9e-24 86.3 0.0 4.5e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 KPI40299.1 - 2.6e-06 26.9 0.0 0.00023 20.5 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 KPI40299.1 - 0.00017 21.5 0.0 0.00045 20.1 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KPI40299.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KPI40299.1 - 0.023 14.5 2.3 0.076 12.8 0.5 2.4 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SH3_1 PF00018.28 KPI40302.1 - 1.5e-14 53.3 0.0 2.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI40302.1 - 5.8e-14 51.7 0.0 1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI40302.1 - 9e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain adh_short_C2 PF13561.6 KPI40303.1 - 1.2e-49 169.0 0.1 1.4e-49 168.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40303.1 - 3.2e-39 134.4 0.2 3.9e-39 134.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40303.1 - 2.8e-10 40.4 0.2 4.3e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI40303.1 - 0.00033 20.2 0.1 0.00045 19.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KPI40303.1 - 0.01 15.1 0.6 0.8 9.0 0.4 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KPI40303.1 - 0.059 12.5 0.3 0.083 12.0 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KPI40303.1 - 0.073 13.0 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding MA3 PF02847.17 KPI40303.1 - 0.076 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 MA3 domain DUF2325 PF10087.9 KPI40303.1 - 0.094 12.8 0.1 0.24 11.6 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) IL15 PF02372.15 KPI40303.1 - 0.12 12.4 0.3 0.31 11.1 0.2 1.7 1 1 0 1 1 1 0 Interleukin 15 DUF1218 PF06749.12 KPI40304.1 - 0.029 14.9 0.2 0.051 14.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Pannexin_like PF12534.8 KPI40304.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Sugar_tr PF00083.24 KPI40309.1 - 2.7e-107 359.4 21.2 4e-107 358.9 21.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40309.1 - 3.1e-28 98.7 30.1 7.9e-27 94.1 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KPI40309.1 - 4.8 5.3 12.8 0.46 8.7 1.6 2.6 3 0 0 3 3 3 0 BT1 family DUF726 PF05277.12 KPI40310.1 - 9e-101 337.2 0.5 1.3e-100 336.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 KPI40310.1 - 0.0032 17.5 4.2 0.0032 17.5 4.2 2.4 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III PE-PPE PF08237.11 KPI40310.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain DUF900 PF05990.12 KPI40310.1 - 0.085 12.3 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 KPI40310.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) CcdA PF07362.12 KPI40310.1 - 0.64 10.5 3.2 3.7 8.1 0.6 3.2 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Abhydrolase_6 PF12697.7 KPI40310.1 - 0.9 10.1 7.9 0.38 11.3 0.2 2.8 2 1 1 3 3 3 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 KPI40311.1 - 1.8e-32 112.9 0.0 3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPI40311.1 - 0.00043 19.5 0.0 0.00058 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KPI40311.1 - 0.00091 18.4 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KPI40311.1 - 0.00099 18.8 4.2 0.14 11.7 3.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPI40311.1 - 0.0011 18.3 0.2 0.0018 17.5 0.2 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KPI40311.1 - 0.0046 15.7 1.3 0.0067 15.2 1.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPI40311.1 - 0.0096 15.2 0.0 0.034 13.4 0.1 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI40311.1 - 0.033 13.4 3.5 0.073 12.3 3.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI40311.1 - 0.15 12.3 0.8 0.33 11.2 0.8 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI40311.1 - 0.18 11.8 0.7 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding OTU PF02338.19 KPI40312.1 - 3.7e-22 79.2 0.2 1.2e-21 77.6 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KPI40312.1 - 1.8e-05 24.3 0.2 0.0046 16.4 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain NUC194 PF08163.12 KPI40312.1 - 0.68 8.8 2.5 0.97 8.3 2.5 1.2 1 0 0 1 1 1 0 NUC194 domain adh_short PF00106.25 KPI40313.1 - 6e-92 306.5 17.2 3.6e-49 166.9 3.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40313.1 - 5.3e-71 238.9 14.8 1.3e-38 132.9 2.4 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40313.1 - 8.5e-30 104.0 10.3 8.3e-15 55.2 2.7 2.6 2 1 0 2 2 2 2 KR domain DUF543 PF04418.12 KPI40313.1 - 0.025 14.6 3.0 2.1 8.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) THF_DHG_CYH_C PF02882.19 KPI40313.1 - 0.036 13.4 4.2 1.4 8.2 1.0 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SAM_LFY PF01698.16 KPI40313.1 - 0.4 10.7 1.5 4.1 7.4 0.0 3.3 4 0 0 4 4 4 0 Floricaula / Leafy protein SAM domain 3HCDH_N PF02737.18 KPI40313.1 - 1.1 9.2 8.7 3.3 7.6 0.9 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KPI40314.1 - 5.8e-78 262.7 0.0 7e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KPI40315.1 - 0.001 18.9 0.0 0.0034 17.2 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KPI40315.1 - 0.17 11.8 0.0 0.61 10.0 0.1 1.8 2 0 0 2 2 2 0 F-box domain adh_short_C2 PF13561.6 KPI40316.1 - 8.9e-13 48.3 0.1 1.2e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40316.1 - 1.4e-10 41.0 0.1 2.1e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KPI40316.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KPI40317.1 - 1.3e-22 80.0 1.7 2.3e-22 79.2 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI40317.1 - 0.0046 17.0 0.3 0.027 14.6 0.3 2.2 1 1 0 1 1 1 1 Berberine and berberine like Gal11_ABD1 PF18535.1 KPI40318.1 - 0.17 12.0 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) DUF3461 PF11944.8 KPI40319.1 - 0.094 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) PH_2 PF08458.10 KPI40319.1 - 0.17 12.2 0.2 0.81 10.1 0.1 2.0 2 0 0 2 2 2 0 Plant pleckstrin homology-like region CBAH PF02275.18 KPI40320.1 - 3e-35 122.4 0.0 5.7e-34 118.2 0.0 2.0 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family ADH_zinc_N PF00107.26 KPI40321.1 - 2.6e-09 37.1 0.1 5.1e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI40321.1 - 9.8e-07 28.6 0.3 3.3e-06 26.9 0.2 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PQQ_3 PF13570.6 KPI40321.1 - 0.44 11.1 1.8 26 5.5 0.1 2.8 2 1 0 2 2 2 0 PQQ-like domain COPI_C PF06957.11 KPI40322.1 - 2 7.1 5.1 2.8 6.6 5.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ATG11 PF10377.9 KPI40323.1 - 2.2e-46 157.1 0.1 2.2e-46 157.1 0.1 4.9 5 0 0 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 KPI40323.1 - 1.8e-09 37.2 0.3 1.8e-09 37.2 0.3 6.0 3 2 2 5 5 5 2 Autophagy protein Apg17 HrpB7 PF09486.10 KPI40323.1 - 0.0043 17.4 6.4 0.0043 17.4 6.4 7.6 7 2 1 8 8 8 2 Bacterial type III secretion protein (HrpB7) HAMP PF00672.25 KPI40323.1 - 0.059 13.8 0.0 0.43 11.0 0.0 2.6 1 0 0 1 1 1 0 HAMP domain PLAC9 PF15205.6 KPI40323.1 - 1.4 9.4 4.7 13 6.2 0.0 3.7 4 0 0 4 4 4 0 Placenta-specific protein 9 Fez1 PF06818.15 KPI40323.1 - 1.4 9.3 88.0 0.02 15.3 15.1 6.8 5 2 1 6 6 6 0 Fez1 TruB_C_2 PF16198.5 KPI40323.1 - 3.3 7.9 5.7 39 4.5 0.1 3.8 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain DNA_topoisoIV PF00521.20 KPI40324.1 - 1.2e-127 426.4 0.1 1.9e-127 425.7 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KPI40324.1 - 1.7e-47 160.8 1.6 7.8e-47 158.7 1.6 2.3 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KPI40324.1 - 1.1e-23 83.6 4.1 4.6e-23 81.6 4.1 2.1 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KPI40324.1 - 2.2e-12 47.5 0.5 1e-11 45.3 0.2 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KPI40324.1 - 8.5e-07 29.2 0.0 3.4e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Toprim domain DUF3785 PF12653.7 KPI40324.1 - 0.17 12.0 0.8 0.42 10.7 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Tyr_Deacylase PF02580.16 KPI40325.1 - 4.9e-53 179.5 0.0 5.6e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SeqA_N PF17206.3 KPI40325.1 - 0.23 10.8 0.0 0.61 9.5 0.0 1.7 2 0 0 2 2 2 0 SeqA protein N-terminal domain TPR_19 PF14559.6 KPI40326.1 - 0.0038 17.7 14.4 0.33 11.5 0.0 5.4 5 2 0 5 5 5 2 Tetratricopeptide repeat DUF4407 PF14362.6 KPI40326.1 - 0.033 13.5 3.3 0.065 12.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin PF00804.25 KPI40326.1 - 0.066 12.9 3.0 0.63 9.7 0.1 2.6 2 0 0 2 2 2 0 Syntaxin TPR_14 PF13428.6 KPI40326.1 - 0.15 13.0 9.8 11 7.2 0.1 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat PilO PF04350.13 KPI40326.1 - 4.6 7.4 5.4 1.7 8.8 0.3 2.6 3 0 0 3 3 3 0 Pilus assembly protein, PilO peroxidase PF00141.23 KPI40327.1 - 1.2e-82 277.0 0.0 2e-43 148.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 KPI40327.1 - 0.12 12.6 0.0 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ORF6N PF10543.9 KPI40327.1 - 0.12 12.6 0.1 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 ORF6N domain BTB PF00651.31 KPI40328.1 - 7.2e-11 42.3 0.0 1.7e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain HEPN PF05168.14 KPI40328.1 - 0.017 15.2 0.0 0.04 14.1 0.0 1.7 1 1 0 1 1 1 0 HEPN domain MIF4G PF02854.19 KPI40329.1 - 6e-19 68.5 0.2 1.2e-18 67.5 0.2 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KPI40329.1 - 6.8e-06 26.0 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 MA3 domain CDV3 PF15359.6 KPI40329.1 - 0.0017 18.9 3.2 0.0017 18.9 3.2 2.2 2 1 0 2 2 2 1 Carnitine deficiency-associated protein 3 F-box-like PF12937.7 KPI40330.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 F-box-like TRI12 PF06609.13 KPI40331.1 - 3.2e-74 250.4 25.4 4.2e-74 250.1 25.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI40331.1 - 1.1e-31 110.1 46.2 1.9e-30 106.0 44.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40331.1 - 6.9e-13 48.3 12.4 6.9e-13 48.3 12.4 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Abhydrolase_6 PF12697.7 KPI40332.1 - 2.1e-15 58.0 1.5 2.5e-15 57.7 1.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI40332.1 - 3.5e-07 30.1 0.0 6.3e-06 26.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI40332.1 - 0.003 16.9 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KPI40332.1 - 0.0077 15.0 0.0 0.42 9.3 0.0 2.1 2 0 0 2 2 2 2 Ndr family Peptidase_S9 PF00326.21 KPI40332.1 - 0.05 13.1 0.0 0.55 9.7 0.0 2.5 3 1 0 3 3 3 0 Prolyl oligopeptidase family MFS_1 PF07690.16 KPI40333.1 - 2.7e-25 89.0 35.5 4e-25 88.5 35.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40333.1 - 4.3e-06 25.9 27.4 1.9e-05 23.8 7.1 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KPI40333.1 - 0.0071 15.3 13.2 0.031 13.1 0.1 2.8 1 1 2 3 3 3 3 MFS_1 like family G_glu_transpept PF01019.21 KPI40334.1 - 5.1e-136 454.5 0.5 4e-135 451.5 0.5 1.9 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase adh_short PF00106.25 KPI40335.1 - 2.9e-25 88.9 0.7 1.6e-23 83.2 0.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40335.1 - 5.1e-16 58.9 0.3 6.6e-15 55.3 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40335.1 - 5.7e-07 29.6 0.4 1e-06 28.8 0.4 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KPI40335.1 - 0.012 15.7 0.3 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KPI40335.1 - 0.032 13.3 0.3 0.079 12.1 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PALP PF00291.25 KPI40335.1 - 0.052 13.0 0.3 0.086 12.2 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KPI40336.1 - 2.1e-27 95.9 0.0 3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40336.1 - 6.4e-18 65.2 0.0 8.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40336.1 - 3.1e-07 30.5 0.0 4.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI40336.1 - 0.00025 20.6 0.0 0.00044 19.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI40336.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MAD PF05557.13 KPI40338.1 - 1.7e-53 182.1 52.8 2.4e-53 181.5 52.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein CLZ PF16526.5 KPI40338.1 - 0.00047 20.5 0.9 0.00047 20.5 0.9 6.9 5 1 1 6 6 6 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 KPI40338.1 - 0.0087 15.6 12.1 0.0087 15.6 12.1 4.3 1 1 3 4 4 4 2 Golgin subfamily A member 5 DUF4407 PF14362.6 KPI40338.1 - 2.5 7.4 58.3 0.099 12.0 11.3 4.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) MFS_MOT1 PF16983.5 KPI40340.1 - 6.1e-44 149.0 29.3 1.7e-28 99.2 8.4 4.2 4 0 0 4 4 4 3 Molybdate transporter of MFS superfamily Trp_oprn_chp PF09534.10 KPI40340.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pyr_redox_2 PF07992.14 KPI40341.1 - 4e-22 78.8 0.1 7.7e-21 74.6 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI40341.1 - 6.3e-10 38.8 0.4 1.4e-05 24.5 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI40341.1 - 5.9e-08 31.8 0.3 0.0011 17.8 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 KPI40341.1 - 7.8e-07 28.5 1.1 0.011 14.8 0.2 2.3 1 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KPI40341.1 - 2e-06 27.2 5.6 0.0093 15.1 0.1 2.5 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI40341.1 - 5.1e-06 25.8 0.6 1.8e-05 24.0 0.1 2.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KPI40341.1 - 4.1e-05 23.6 1.3 0.0065 16.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KPI40341.1 - 0.00027 20.4 0.2 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KPI40341.1 - 0.00049 19.8 3.2 0.0042 16.7 0.3 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI40341.1 - 0.0027 17.9 0.1 0.006 16.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KPI40341.1 - 0.0063 15.8 0.2 0.015 14.5 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KPI40341.1 - 0.0093 15.3 0.1 0.02 14.2 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KPI40341.1 - 0.01 15.2 0.4 0.016 14.6 0.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPI40341.1 - 0.023 14.0 0.1 0.06 12.6 0.1 1.7 1 0 0 1 1 1 0 Thi4 family AlphaC_N PF08829.10 KPI40341.1 - 0.061 13.3 0.1 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Alpha C protein N terminal Conotoxin_I2 PF17557.2 KPI40342.1 - 0.025 14.7 11.6 0.047 13.8 11.6 1.4 1 0 0 1 1 1 0 I2-superfamily conotoxins WAP PF00095.21 KPI40342.1 - 0.026 14.9 10.2 0.041 14.3 10.2 1.3 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' UQ_con PF00179.26 KPI40343.1 - 4.2e-38 130.2 0.0 5.7e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPI40343.1 - 0.035 14.4 0.0 0.064 13.5 0.0 1.3 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KPI40343.1 - 0.055 13.2 0.0 0.072 12.8 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B COQ7 PF03232.13 KPI40345.1 - 1.9e-65 219.9 0.0 2.6e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 SOAR PF16533.5 KPI40345.1 - 0.02 14.9 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF4455 PF14643.6 KPI40345.1 - 0.056 12.1 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) UPF0184 PF03670.13 KPI40345.1 - 0.057 13.8 1.3 0.49 10.8 1.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) NmrA PF05368.13 KPI40346.1 - 4.9e-19 68.8 0.0 7.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI40346.1 - 9.1e-13 48.5 0.0 2.7e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NFRKB_winged PF14465.6 KPI40346.1 - 0.18 12.0 0.1 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 NFRKB Winged Helix-like MBF1 PF08523.10 KPI40347.1 - 2.9e-24 85.3 3.5 6.4e-24 84.2 3.5 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KPI40347.1 - 3.7e-10 39.7 0.0 5.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KPI40347.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF5449 PF17528.2 KPI40348.1 - 0.038 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5449) PAM2 PF07145.15 KPI40348.1 - 0.049 13.3 1.1 0.1 12.3 1.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Saf_2TM PF18303.1 KPI40349.1 - 0.0076 15.8 1.0 0.81 9.3 0.0 3.1 3 0 0 3 3 3 1 SAVED-fused 2TM effector domain EphA2_TM PF14575.6 KPI40349.1 - 0.015 16.2 0.2 0.11 13.4 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KPI40349.1 - 0.018 15.0 0.6 0.041 13.8 0.6 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 KPI40349.1 - 0.19 11.1 0.2 0.32 10.4 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) HIG_1_N PF04588.13 KPI40349.1 - 0.39 11.0 2.1 6.6 7.0 0.0 3.3 4 0 0 4 4 4 0 Hypoxia induced protein conserved region Mucin PF01456.17 KPI40349.1 - 1.2 9.1 20.0 2.5 8.1 20.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LPG_synthase_TM PF03706.13 KPI40349.1 - 7.4 6.0 12.1 12 5.3 4.5 3.4 4 0 0 4 4 4 0 Lysylphosphatidylglycerol synthase TM region CssAB PF16831.5 KPI40350.1 - 0.13 12.6 0.8 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 DUF4387 PF14330.6 KPI40351.1 - 5.8e-25 87.8 0.0 1.1e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KPI40351.1 - 0.00013 20.8 0.0 0.00033 19.5 0.0 1.5 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA TP_methylase PF00590.20 KPI40353.1 - 4e-22 79.2 0.1 2.1e-21 76.9 0.1 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ATP_sub_h PF10775.9 KPI40355.1 - 3.6e-25 87.8 1.4 5.4e-25 87.2 1.4 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h FAD_binding_4 PF01565.23 KPI40357.1 - 3.9e-22 78.5 0.4 7.9e-22 77.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI40357.1 - 0.092 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.23 KPI40358.1 - 1.2e-31 109.3 3.1 2.1e-31 108.5 3.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF812 PF05667.11 KPI40360.1 - 0.0055 15.7 22.4 0.0069 15.3 22.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Laminin_II PF06009.12 KPI40360.1 - 0.024 14.7 5.4 0.024 14.7 5.4 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF3584 PF12128.8 KPI40360.1 - 0.024 12.2 30.9 0.031 11.8 30.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 KPI40360.1 - 0.11 12.7 35.1 1.2 9.4 17.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KPI40360.1 - 0.16 10.8 33.4 0.052 12.4 19.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ZnuA PF01297.17 KPI40360.1 - 0.2 11.0 6.4 0.28 10.5 6.4 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1759 PF03564.15 KPI40360.1 - 0.52 10.2 7.8 0.26 11.2 2.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4164 PF13747.6 KPI40360.1 - 0.96 9.8 17.8 2.8 8.3 8.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) SpecificRecomb PF10136.9 KPI40360.1 - 1.5 7.1 10.0 2 6.7 10.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF4226 PF10774.9 KPI40360.1 - 1.8 8.9 12.8 3.8 7.8 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4226) NPV_P10 PF05531.12 KPI40360.1 - 3.2 8.3 12.1 22 5.6 7.5 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YlqD PF11068.8 KPI40360.1 - 4.7 7.6 36.9 2.2 8.7 8.9 3.1 1 1 2 3 3 3 0 YlqD protein Latarcin PF10279.9 KPI40360.1 - 5.1 7.6 14.3 97 3.5 0.0 3.5 1 1 1 2 2 1 0 Latarcin precursor Golgin_A5 PF09787.9 KPI40360.1 - 5.2 6.4 38.6 3.4 7.0 13.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4936 PF16290.5 KPI40360.1 - 5.9 7.7 12.3 12 6.7 1.8 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4936) Ank_2 PF12796.7 KPI40361.1 - 1e-25 90.1 0.8 1.8e-08 34.9 0.0 5.9 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI40361.1 - 9.7e-19 67.5 0.4 3e-08 34.0 0.0 6.5 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI40361.1 - 2.2e-16 58.3 0.5 0.0025 18.2 0.0 7.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KPI40361.1 - 4.5e-11 42.8 4.5 0.0038 17.5 0.1 5.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) NACHT PF05729.12 KPI40361.1 - 3.1e-09 37.0 0.0 1e-08 35.3 0.0 1.9 2 0 0 2 2 1 1 NACHT domain Ank PF00023.30 KPI40361.1 - 1.7e-08 34.5 8.9 0.023 15.2 0.0 7.0 7 1 1 8 8 8 3 Ankyrin repeat HET PF06985.11 KPI40361.1 - 2.7e-07 31.0 6.8 1.5e-05 25.4 1.3 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 KPI40361.1 - 0.00067 20.1 0.0 0.014 15.8 0.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KPI40361.1 - 0.0026 17.1 2.8 0.041 13.1 2.8 2.1 1 1 0 1 1 1 1 KAP family P-loop domain MCM PF00493.23 KPI40361.1 - 0.013 14.6 0.0 0.045 12.9 0.0 1.9 1 1 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 KPI40361.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KPI40361.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EH_Signature PF15611.6 KPI40361.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 EH_Signature domain NB-ARC PF00931.22 KPI40361.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KPI40361.1 - 0.18 11.8 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PXA PF02194.15 KPI40364.1 - 0.062 13.3 0.8 0.76 9.7 0.8 2.2 1 1 0 1 1 1 0 PXA domain DUF4716 PF15837.5 KPI40364.1 - 0.52 10.4 9.8 5.3 7.2 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) HET PF06985.11 KPI40365.1 - 2.5e-31 109.0 0.1 4.1e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4904 PF16247.5 KPI40365.1 - 0.042 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) HAUS-augmin3 PF14932.6 KPI40366.1 - 0.011 15.3 0.6 0.019 14.5 0.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IFT57 PF10498.9 KPI40366.1 - 0.094 11.7 1.6 0.15 11.0 1.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMEM43 PF07787.12 KPI40366.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 43 CTU2 PF10288.9 KPI40366.1 - 0.26 11.5 3.8 0.76 10.0 3.8 1.8 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4407 PF14362.6 KPI40366.1 - 0.78 9.0 4.0 1.3 8.3 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KPI40366.1 - 4 7.8 6.6 0.31 11.4 1.7 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KPI40366.1 - 4.8 7.7 8.3 0.4 11.2 3.3 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region His_Phos_1 PF00300.22 KPI40367.1 - 1.5e-10 41.1 2.7 2.7e-05 23.9 0.1 3.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 KPI40369.1 - 0.00049 19.9 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KPI40370.1 - 0.11 12.5 3.0 0.36 10.8 3.0 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KPI40370.1 - 0.26 11.2 3.8 1 9.3 3.8 2.1 1 0 0 1 1 1 0 F-box-like COesterase PF00135.28 KPI40371.1 - 5.6e-21 75.0 0.0 6.7e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family p450 PF00067.22 KPI40372.1 - 5e-67 226.6 0.0 6.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 KPI40373.1 - 5.4e-69 233.4 0.0 7.1e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI40373.1 - 5.1e-05 23.2 0.3 0.00013 21.9 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI40373.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KPI40373.1 - 0.079 11.8 0.0 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KPI40373.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BTB PF00651.31 KPI40374.1 - 3e-10 40.3 0.0 7.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HEPN PF05168.14 KPI40374.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 HEPN domain HET PF06985.11 KPI40375.1 - 6.3e-06 26.6 8.5 3.5e-05 24.2 1.5 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AtuA PF07287.11 KPI40376.1 - 5.9e-110 367.3 0.1 7e-110 367.0 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF3445 PF11927.8 KPI40378.1 - 2.3e-73 246.5 0.0 3.1e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lentivirus_VIF PF05851.11 KPI40378.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Amino_oxidase PF01593.24 KPI40379.1 - 3.1e-51 175.1 0.3 8.1e-50 170.4 0.3 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI40379.1 - 8.5e-15 54.7 0.4 3.2e-14 52.9 0.3 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI40379.1 - 1e-06 28.2 0.6 1.9e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI40379.1 - 7.8e-06 25.9 0.3 0.0048 16.9 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KPI40379.1 - 5.1e-05 22.7 0.1 8.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KPI40379.1 - 5.3e-05 23.7 3.5 0.00025 21.5 0.9 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40379.1 - 9.1e-05 22.2 4.2 0.00056 19.6 4.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPI40379.1 - 0.0016 17.8 0.5 0.0031 16.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KPI40379.1 - 0.0016 17.7 0.4 0.0026 17.0 0.4 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KPI40379.1 - 0.011 14.5 1.6 0.02 13.6 1.6 1.4 1 0 0 1 1 1 0 HI0933-like protein FMO-like PF00743.19 KPI40379.1 - 0.029 12.8 0.1 0.042 12.3 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KPI40379.1 - 0.038 13.1 2.2 0.3 10.1 2.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI40379.1 - 0.055 12.5 3.7 1.1 8.3 3.0 2.1 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KPI40379.1 - 0.057 13.3 0.8 0.11 12.3 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KPI40379.1 - 0.13 11.6 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 KPI40379.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Prenylcysteine lyase 2-Hacid_dh_C PF02826.19 KPI40379.1 - 0.23 10.8 0.2 0.43 9.9 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FmdA_AmdA PF03069.15 KPI40381.1 - 1.4e-176 586.9 0.0 1.6e-176 586.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family APH PF01636.23 KPI40382.1 - 3.8e-14 53.2 0.3 6.5e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPI40382.1 - 7.9e-06 25.6 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4936 PF16290.5 KPI40382.1 - 0.048 14.4 0.1 0.14 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) GST_C_2 PF13410.6 KPI40382.1 - 0.12 12.4 0.2 8.5 6.5 0.0 3.3 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain SRP14 PF02290.15 KPI40383.1 - 5.5e-24 84.4 0.2 7.6e-24 83.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein F-box-like PF12937.7 KPI40384.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 F-box-like FXR_C1 PF16096.5 KPI40384.1 - 0.52 10.5 3.2 0.94 9.7 3.2 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Thiolase_N PF00108.23 KPI40386.1 - 6.2e-88 294.5 1.1 6.2e-88 294.5 1.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI40386.1 - 2.2e-39 133.9 0.8 2.2e-39 133.9 0.8 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPI40386.1 - 2.8e-05 23.8 2.5 2.8e-05 23.8 2.5 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPI40386.1 - 0.13 12.1 6.6 2.6 7.9 0.2 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.21 KPI40387.1 - 2.5e-13 50.1 0.0 3.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI40387.1 - 1.8e-06 27.2 0.0 3.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KPI40387.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI40387.1 - 0.0052 16.2 0.0 0.03 13.7 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPI40387.1 - 0.0082 15.7 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KPI40387.1 - 0.01 15.0 0.1 0.037 13.2 0.1 1.8 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.25 KPI40387.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Abhydrolase_3 PF07859.13 KPI40388.1 - 9.1e-34 117.2 0.1 1.5e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCM PF04072.14 KPI40390.1 - 7.8e-18 65.1 0.0 1.2e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LCM PF04072.14 KPI40391.1 - 1.1e-13 51.5 0.3 1.1e-11 45.1 0.3 2.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Met_asp_mut_E PF06368.11 KPI40391.1 - 0.062 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Fungal_trans PF04082.18 KPI40393.1 - 2.7e-13 49.6 0.1 5e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI40393.1 - 1.9e-07 31.1 12.4 4.1e-07 30.0 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5121 PF17165.4 KPI40393.1 - 0.031 14.7 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) DNA_primase_lrg PF04104.14 KPI40393.1 - 0.45 9.9 2.3 0.8 9.0 2.3 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit COesterase PF00135.28 KPI40394.1 - 2.5e-72 244.4 0.0 3.6e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI40394.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like_2 PF13013.6 KPI40395.1 - 0.00046 20.1 0.0 0.00061 19.7 0.0 1.4 1 1 0 1 1 1 1 F-box-like domain MRC1 PF09444.10 KPI40396.1 - 1.1e-34 120.0 24.3 1.1e-34 120.0 24.3 9.5 6 3 1 8 8 8 2 MRC1-like domain FMO-like PF00743.19 KPI40397.1 - 4.8e-17 61.6 0.2 5.8e-16 58.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI40397.1 - 6.4e-15 55.2 0.1 2.4e-14 53.3 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI40397.1 - 1.3e-13 50.8 0.0 5.4e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI40397.1 - 1.4e-11 44.4 0.0 4.6e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI40397.1 - 6e-11 42.1 0.1 5.4e-08 32.4 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KPI40397.1 - 1.1e-10 41.7 0.7 7.8e-06 25.7 0.0 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPI40397.1 - 9.8e-07 28.2 0.0 1.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 KPI40397.1 - 7.4e-06 24.8 0.0 0.035 12.7 0.0 2.3 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 KPI40397.1 - 9.4e-05 22.9 0.0 0.35 11.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI40397.1 - 0.00033 19.8 0.0 0.23 10.4 0.0 3.4 3 1 1 4 4 4 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KPI40397.1 - 0.0016 18.5 1.7 1.6 8.7 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KPI40397.1 - 0.0048 16.2 0.0 0.05 12.9 0.0 2.4 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 KPI40397.1 - 0.011 15.8 0.0 0.24 11.5 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KPI40397.1 - 0.032 13.3 0.0 0.22 10.6 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KPI40397.1 - 0.047 12.5 0.2 2.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 KPI40397.1 - 0.1 12.0 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI40397.1 - 0.11 11.2 0.3 2.4 6.8 0.0 2.9 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_7 PF13241.6 KPI40397.1 - 0.17 12.4 0.0 2.6 8.5 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding GIDA PF01134.22 KPI40397.1 - 0.23 10.5 1.8 9.8 5.1 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Abhydrolase_1 PF00561.20 KPI40398.1 - 5e-05 23.1 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4951 PF16309.5 KPI40398.1 - 0.072 13.1 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) DUF1057 PF06342.12 KPI40398.1 - 0.15 11.1 0.0 0.41 9.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Adaptin_N PF01602.20 KPI40399.1 - 1.7e-136 455.9 2.0 2.1e-136 455.6 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPI40399.1 - 2e-62 210.0 0.6 1e-60 204.4 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPI40399.1 - 3.8e-18 65.7 0.1 1.1e-09 38.6 0.0 5.5 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KPI40399.1 - 3.2e-13 48.7 2.6 0.01 16.0 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.23 KPI40399.1 - 0.0043 17.1 0.9 3.9 7.6 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KPI40399.1 - 0.0064 16.1 0.3 0.9 9.0 0.0 3.4 2 1 1 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 KPI40399.1 - 0.012 16.1 9.1 1.1 9.8 0.0 5.1 4 1 1 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 KPI40399.1 - 0.014 15.5 0.6 2.2 8.5 0.0 3.8 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 bZIP_1 PF00170.21 KPI40401.1 - 7.2e-05 22.8 3.2 0.00012 22.1 3.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF2828 PF11443.8 KPI40401.1 - 0.039 12.1 1.5 0.047 11.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Deltaretro_Tax PF05599.11 KPI40401.1 - 0.42 11.2 4.5 0.49 10.9 3.0 1.8 1 1 0 2 2 2 0 Deltaretrovirus Tax protein bZIP_2 PF07716.15 KPI40401.1 - 0.85 9.8 11.7 4 7.6 11.7 2.0 1 1 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.16 KPI40402.1 - 4e-26 91.8 21.7 8.6e-24 84.1 19.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF809 PF05663.11 KPI40402.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Trp_oprn_chp PF09534.10 KPI40402.1 - 0.67 9.7 8.0 0.14 12.0 0.3 2.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3094 PF11293.8 KPI40402.1 - 0.78 9.5 4.5 0.59 9.9 0.7 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3094) Sugar_tr PF00083.24 KPI40403.1 - 2.2e-94 316.9 19.9 2.6e-94 316.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40403.1 - 3.3e-28 98.6 19.0 3.3e-28 98.6 19.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI40403.1 - 0.89 8.3 15.8 2.3 7.0 9.3 2.3 2 1 0 2 2 2 0 MFS_1 like family BTB PF00651.31 KPI40404.1 - 0.0042 17.3 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_76 PF03663.14 KPI40405.1 - 1.3e-125 419.8 14.6 1.6e-125 419.5 14.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPI40405.1 - 0.022 13.8 0.8 0.022 13.8 0.8 3.1 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 EHN PF06441.12 KPI40406.1 - 3.4e-24 85.3 0.4 6.7e-24 84.3 0.4 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI40406.1 - 3.6e-15 56.3 0.0 5.5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI40406.1 - 0.00083 20.0 6.5 0.0023 18.5 6.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Isochorismatase PF00857.20 KPI40407.1 - 5.5e-44 150.4 0.0 6.5e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family adh_short PF00106.25 KPI40408.1 - 2.6e-29 102.1 0.0 2.9e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40408.1 - 1.7e-21 76.9 0.0 5.2e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40408.1 - 0.00018 21.5 0.1 0.056 13.3 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KPI40408.1 - 0.042 13.3 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TLD PF07534.16 KPI40409.1 - 1.5e-08 34.9 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 TLD CRAL_TRIO PF00650.20 KPI40410.1 - 1.1e-44 152.0 0.0 2.5e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPI40410.1 - 2.5e-14 53.2 0.1 6.3e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Methyltransf_12 PF08242.12 KPI40410.1 - 4.3e-11 43.4 0.1 2e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40410.1 - 6.5e-10 39.5 0.0 1.6e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI40410.1 - 1.9e-09 38.1 0.0 5.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40410.1 - 2.3e-09 37.2 0.0 5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CRAL_TRIO_2 PF13716.6 KPI40410.1 - 2e-06 28.0 0.0 3.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Methyltransf_23 PF13489.6 KPI40410.1 - 1.4e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI40410.1 - 0.0005 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KPI40411.1 - 1.5e-54 185.0 0.5 1.8e-54 184.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40411.1 - 2.9e-43 147.6 2.9 3.6e-43 147.3 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40411.1 - 6.3e-09 36.0 1.1 1.1e-08 35.3 0.9 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI40411.1 - 0.00057 19.4 0.4 0.0013 18.3 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KPI40411.1 - 0.0075 16.4 0.4 0.04 14.0 0.4 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KPI40411.1 - 0.01 16.6 0.1 0.019 15.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 KPI40411.1 - 0.019 14.9 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KPI40411.1 - 0.03 13.9 0.2 0.22 11.1 0.2 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans_2 PF11951.8 KPI40413.1 - 5.9e-07 28.6 0.0 7.5e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSXT PF05030.12 KPI40414.1 - 0.00019 21.0 0.8 0.023 14.3 0.0 3.2 3 1 0 3 3 3 2 SSXT protein (N-terminal region) Ribonuclease_3 PF00636.26 KPI40415.1 - 6.3e-13 49.3 0.0 4.4e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPI40415.1 - 9.7e-13 48.4 0.0 2.1e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KPI40415.1 - 0.011 16.4 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Cupin_2 PF07883.11 KPI40416.1 - 4e-06 26.4 0.0 6.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2917 PF11142.8 KPI40416.1 - 0.062 12.7 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Glyco_trans_1_4 PF13692.6 KPI40417.1 - 1.9e-08 34.8 0.0 7.4e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KPI40417.1 - 3.8e-05 23.3 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPI40417.1 - 0.00019 21.5 0.5 0.00084 19.4 0.7 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KPI40417.1 - 0.00038 20.9 0.6 0.00076 20.0 0.4 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Peptidase_S28 PF05577.12 KPI40418.1 - 1.1e-36 126.6 0.2 6.7e-36 124.0 0.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF468 PF04318.12 KPI40418.1 - 0.087 13.5 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF468) SUN PF03856.13 KPI40419.1 - 2.1e-79 266.4 11.1 2.9e-79 266.0 11.1 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Integrin_b_cyt PF08725.11 KPI40419.1 - 0.22 11.2 0.1 0.44 10.3 0.1 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Aldo_ket_red PF00248.21 KPI40420.1 - 3e-45 154.7 0.0 3.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SnoaL_2 PF12680.7 KPI40422.1 - 8e-05 23.2 0.1 0.0001 22.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPI40422.1 - 0.081 13.3 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) F-box PF00646.33 KPI40423.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain His_Phos_1 PF00300.22 KPI40424.1 - 8.9e-11 41.8 0.2 2.5e-10 40.4 0.2 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.18 KPI40425.1 - 3.1e-22 78.9 0.2 8.6e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI40425.1 - 2e-07 31.0 9.8 4.1e-07 30.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KPI40427.1 - 4.7e-13 49.3 0.0 1.3e-09 38.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40427.1 - 0.00013 21.8 0.1 0.0039 17.0 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40427.1 - 0.00014 22.5 0.0 0.00059 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI40427.1 - 0.00029 21.5 0.1 0.023 15.4 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI40427.1 - 0.00048 20.8 0.0 0.0012 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TMEM234 PF10639.9 KPI40428.1 - 2.9e-35 120.8 0.8 3.5e-35 120.5 0.8 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KPI40428.1 - 0.0013 18.9 6.9 0.095 12.9 6.9 2.1 1 1 0 1 1 1 1 EamA-like transporter family EI24 PF07264.11 KPI40428.1 - 0.0099 16.1 2.7 0.012 15.9 2.7 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2985 PF11204.8 KPI40428.1 - 0.029 14.5 2.6 0.55 10.4 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) zf-primase PF09329.11 KPI40429.1 - 2.8e-15 55.9 1.1 4.7e-15 55.1 1.1 1.4 1 0 0 1 1 1 1 Primase zinc finger Pannexin_like PF12534.8 KPI40429.1 - 1.9 7.5 3.0 4 6.4 3.0 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 FAD_binding_3 PF01494.19 KPI40431.1 - 1.9e-49 168.8 0.0 2.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPI40431.1 - 4.4e-05 22.9 0.1 7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40431.1 - 0.00012 21.7 0.2 0.00095 18.8 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI40431.1 - 0.00022 21.4 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI40431.1 - 0.00047 19.5 0.0 0.00092 18.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI40431.1 - 0.0006 19.0 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI40431.1 - 0.0042 15.8 0.0 0.006 15.3 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 KPI40431.1 - 0.0055 15.8 0.0 0.059 12.4 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 KPI40431.1 - 0.0055 15.8 0.1 0.0081 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KPI40431.1 - 0.038 13.3 0.1 0.059 12.7 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KPI40431.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KPI40431.1 - 0.05 14.2 0.0 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI40431.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 KPI40431.1 - 0.16 11.4 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF4736 PF15883.5 KPI40432.1 - 0.4 10.4 1.5 0.92 9.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) p450 PF00067.22 KPI40433.1 - 4.7e-67 226.7 0.0 6.2e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rib_hydrolayse PF02267.17 KPI40434.1 - 0.046 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosyl cyclase C2 PF00168.30 KPI40436.1 - 7.3e-16 58.3 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.16 KPI40437.1 - 9.4e-17 61.0 32.1 2.4e-09 36.6 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40437.1 - 5.4e-14 51.9 20.7 1.7e-13 50.2 20.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter F-112 PF09645.10 KPI40438.1 - 2.5 8.2 4.1 7.2 6.8 0.6 2.5 2 0 0 2 2 2 0 F-112 protein FAD_binding_3 PF01494.19 KPI40439.1 - 2.3e-08 33.7 0.0 2.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Plus-3 PF03126.18 KPI40440.1 - 4.7e-25 88.2 0.0 1.7e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain Fungal_trans PF04082.18 KPI40441.1 - 1.3e-17 63.8 1.4 2.4e-17 62.8 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI40441.1 - 2.5e-09 37.1 12.3 3.7e-09 36.5 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.11 KPI40441.1 - 0.14 12.2 0.2 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PikAIV_N PF18605.1 KPI40441.1 - 0.29 10.7 1.9 0.69 9.5 1.9 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain bZIP_1 PF00170.21 KPI40441.1 - 1.2 9.3 8.3 1 9.5 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor Gpr1_Fun34_YaaH PF01184.19 KPI40442.1 - 0.025 14.2 4.4 0.038 13.6 4.4 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family YtpI PF14007.6 KPI40442.1 - 0.2 11.8 7.0 0.2 11.8 5.8 1.6 1 1 0 1 1 1 0 YtpI-like protein Evr1_Alr PF04777.13 KPI40443.1 - 1.5e-28 99.2 0.9 1.5e-28 99.2 0.9 1.9 2 0 0 2 2 2 1 Erv1 / Alr family DUF755 PF05501.11 KPI40443.1 - 0.55 10.5 8.3 1.4 9.2 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PRCC PF10253.9 KPI40443.1 - 7 7.4 8.1 24 5.6 8.1 1.8 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting NAD_binding_10 PF13460.6 KPI40444.1 - 5.2e-16 59.1 0.0 8.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI40444.1 - 5.9e-14 52.2 0.0 8.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KPI40444.1 - 3e-07 30.8 0.0 5.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KPI40444.1 - 6.9e-06 26.5 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KPI40444.1 - 6.1e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI40444.1 - 0.00026 20.3 0.0 0.00069 18.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KPI40444.1 - 0.00046 19.3 0.0 0.00072 18.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KPI40444.1 - 0.0047 17.0 0.1 0.0067 16.5 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KPI40444.1 - 0.0047 17.0 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.6 KPI40444.1 - 0.044 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain GDP_Man_Dehyd PF16363.5 KPI40444.1 - 0.046 13.1 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_3 PF03447.16 KPI40444.1 - 0.13 13.0 0.0 15 6.3 0.0 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NTP_transf_9 PF04248.12 KPI40445.1 - 9.8e-18 63.8 0.1 1.3e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) COX4 PF02936.14 KPI40447.1 - 0.0087 16.1 1.8 0.016 15.3 0.0 2.2 2 1 1 3 3 3 1 Cytochrome c oxidase subunit IV TNFR_16_TM PF18422.1 KPI40447.1 - 0.012 15.5 0.4 0.02 14.9 0.4 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3328 PF11807.8 KPI40447.1 - 0.064 13.0 0.1 0.064 13.0 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Synaptobrevin PF00957.21 KPI40447.1 - 0.15 11.9 0.3 0.35 10.7 0.3 1.6 1 0 0 1 1 1 0 Synaptobrevin TP53IP5 PF15331.6 KPI40447.1 - 0.37 10.9 3.7 0.67 10.1 3.7 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF2140 PF09911.9 KPI40447.1 - 8 6.0 6.7 1 8.9 0.1 2.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DNA_binding_1 PF01035.20 KPI40448.1 - 3e-21 75.3 0.0 5.7e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Acyl-CoA_dh_1 PF00441.24 KPI40449.1 - 8.8e-19 68.2 2.5 1.8e-18 67.2 2.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI40449.1 - 2e-07 31.7 0.0 2.1e-06 28.4 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI40449.1 - 2.5e-05 24.4 0.0 6.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI40449.1 - 0.99 9.7 7.1 0.061 13.6 1.4 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans_2 PF11951.8 KPI40450.1 - 4.9e-46 157.3 3.6 6.6e-46 156.9 3.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-CCHC PF00098.23 KPI40451.1 - 3.8e-43 143.7 85.7 4.6e-06 26.5 5.1 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_4 PF14392.6 KPI40451.1 - 7e-08 32.1 55.8 0.08 12.7 0.4 10.2 9 1 1 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 KPI40451.1 - 6.5e-06 25.9 72.6 0.0068 16.2 1.8 10.2 10 0 0 10 10 10 7 Zinc knuckle zf-CCHC_6 PF15288.6 KPI40451.1 - 0.0072 16.1 1.0 0.0072 16.1 1.0 9.0 7 3 3 10 10 10 4 Zinc knuckle zf-CCHC_3 PF13917.6 KPI40451.1 - 0.13 12.2 63.4 0.45 10.5 3.5 9.2 4 2 6 10 10 10 0 Zinc knuckle SBF PF01758.16 KPI40452.1 - 7.6e-50 169.3 13.1 7.6e-50 169.3 13.1 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3619 PF12279.8 KPI40452.1 - 0.24 11.7 1.2 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) DUF2388 PF09498.10 KPI40454.1 - 0.0051 16.7 0.3 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2388) MORN_2 PF07661.13 KPI40454.1 - 0.13 12.5 0.1 0.47 10.8 0.1 2.0 1 0 0 1 1 1 0 MORN repeat variant PDZ_1 PF12812.7 KPI40455.1 - 6.9e-52 173.4 0.1 1.2e-35 121.4 0.0 2.9 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 KPI40455.1 - 1.7e-22 81.0 4.4 5.3e-17 63.1 0.6 3.2 2 1 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KPI40455.1 - 1.7e-17 63.0 0.5 4.8e-09 35.9 0.2 4.2 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KPI40455.1 - 1.4e-13 50.9 0.2 0.00038 20.7 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KPI40455.1 - 5.7e-13 49.0 0.2 1.2e-05 25.5 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Trypsin PF00089.26 KPI40455.1 - 5.5e-06 26.3 0.3 0.0021 17.9 0.1 3.2 2 1 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.6 KPI40455.1 - 0.0017 18.2 0.0 0.87 9.6 0.0 3.7 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 KPI40455.1 - 0.0049 15.6 0.1 0.0085 14.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S7 PF00949.21 KPI40455.1 - 0.14 12.0 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 KPI40455.1 - 0.17 11.4 0.4 0.27 10.7 0.4 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Med4 PF10018.9 KPI40456.1 - 1.6e-21 76.9 10.1 4e-21 75.6 10.1 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ATG16 PF08614.11 KPI40456.1 - 0.012 15.9 0.2 0.012 15.9 0.2 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 KPI40456.1 - 0.055 13.5 5.0 0.43 10.6 0.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KPI40456.1 - 1 9.2 5.7 14 5.6 0.5 2.9 2 1 0 2 2 2 0 Septum formation initiator DNA_primase_S PF01896.19 KPI40457.1 - 5.7e-46 156.8 0.0 7.6e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Inhibitor_I10 PF12559.8 KPI40457.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Serine endopeptidase inhibitors EPSP_synthase PF00275.20 KPI40458.1 - 1.3e-126 422.7 0.0 2.1e-126 422.0 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KPI40458.1 - 1.4e-92 309.6 0.1 2.9e-92 308.5 0.1 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KPI40458.1 - 4.2e-56 190.8 0.0 7.6e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KPI40458.1 - 3e-35 121.7 0.2 2.3e-34 118.8 0.0 2.5 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 KPI40458.1 - 1.2e-23 83.2 0.0 3.3e-23 81.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KPI40458.1 - 2.8e-07 30.5 0.0 6.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.6 KPI40458.1 - 0.00031 21.3 0.1 0.0026 18.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain Pkinase PF00069.25 KPI40460.1 - 4.3e-66 223.0 0.0 5.2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI40460.1 - 8.3e-32 110.5 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI40460.1 - 0.0026 16.8 0.0 0.01 14.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KPI40460.1 - 0.053 13.4 1.2 0.16 11.8 0.0 2.3 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KPI40460.1 - 0.063 12.6 0.1 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.31 KPI40461.1 - 1.6e-10 41.2 0.0 3.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain HEPN PF05168.14 KPI40461.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 HEPN domain FAA_hydrolase PF01557.18 KPI40462.1 - 6.2e-62 209.1 0.0 8.6e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Adaptin_binding PF10199.9 KPI40463.1 - 0.012 16.2 11.0 0.017 15.7 11.0 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SPATIAL PF15256.6 KPI40463.1 - 0.17 12.2 3.8 0.3 11.4 3.8 1.5 1 1 0 1 1 1 0 SPATIAL Paf1 PF03985.13 KPI40463.1 - 0.4 9.6 13.7 0.59 9.1 13.7 1.3 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 KPI40463.1 - 2 6.6 11.9 2.6 6.2 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KPI40463.1 - 2.6 7.3 12.3 4.6 6.5 12.3 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KPI40463.1 - 4.9 5.2 21.2 5.9 5.0 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KPI40463.1 - 6.1 6.2 22.2 7.1 5.9 22.2 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KPI40463.1 - 8.8 4.7 11.4 10 4.5 11.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_1 PF00515.28 KPI40464.1 - 2.8e-09 36.4 0.6 0.0076 16.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI40464.1 - 0.00064 19.6 2.5 6.5 7.1 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI40464.1 - 0.0021 18.3 1.2 0.0051 17.0 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KPI40464.1 - 0.036 14.7 0.2 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KPI40464.1 - 0.059 13.6 0.4 1.5 9.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KPI40464.1 - 0.21 12.0 0.6 1.7 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI40464.1 - 0.42 11.5 0.1 0.42 11.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-S33 PF08293.11 KPI40465.1 - 9.7e-28 96.2 0.1 1.3e-27 95.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 F-box-like PF12937.7 KPI40466.1 - 0.0056 16.5 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 F-box-like Ribosomal_L7Ae PF01248.26 KPI40467.1 - 1.9e-25 88.4 0.0 2.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KPI40467.1 - 0.00033 20.5 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KPI40467.1 - 0.00058 19.9 0.0 0.00068 19.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 Glyco_hydro_4C PF11975.8 KPI40468.1 - 0.024 14.7 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain DUF2935 PF11155.8 KPI40468.1 - 0.058 13.7 0.1 1.1 9.7 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) p450 PF00067.22 KPI40469.1 - 3.5e-68 230.5 0.0 4.3e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Polyketide_cyc2 PF10604.9 KPI40470.1 - 1.9e-07 31.5 0.0 2.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KPI40470.1 - 0.0029 17.8 0.0 0.0046 17.2 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Imm10 PF15588.6 KPI40470.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 10 COPI_C PF06957.11 KPI40471.1 - 0.24 10.1 1.0 0.31 9.7 1.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Homoserine_dh PF00742.19 KPI40472.1 - 1.9e-51 174.4 0.0 2.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KPI40472.1 - 3.2e-13 50.3 0.0 2.1e-12 47.7 0.0 2.2 3 0 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain SNase PF00565.17 KPI40472.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Fungal_trans PF04082.18 KPI40473.1 - 7.7e-06 25.1 1.1 1.2e-05 24.5 1.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 KPI40475.1 - 8.9e-13 48.3 0.0 2.5e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI40475.1 - 8.2e-07 28.9 0.0 9.4e-05 22.1 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPI40475.1 - 1.1e-06 28.3 0.0 0.033 13.5 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KPI40475.1 - 3.3e-06 26.6 0.0 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI40475.1 - 0.00024 20.3 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI40475.1 - 0.00026 19.9 0.1 0.018 13.8 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KPI40475.1 - 0.0009 19.3 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KPI40475.1 - 0.0011 19.5 0.1 1.5 9.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI40475.1 - 0.0013 18.0 0.0 0.0031 16.8 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KPI40475.1 - 0.034 13.4 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KPI40475.1 - 0.053 12.9 0.2 0.2 11.0 0.0 1.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI40475.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KPI40475.1 - 0.15 11.3 0.0 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI40475.1 - 0.26 10.3 0.1 0.39 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A BetR PF08667.10 KPI40476.1 - 0.0052 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 BetR domain DUF1907 PF08925.11 KPI40477.1 - 4.3e-78 262.6 0.0 6.8e-78 262.0 0.0 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1907) Formyl_trans_N PF00551.19 KPI40478.1 - 2.8e-40 138.0 0.2 4.1e-40 137.4 0.2 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KPI40478.1 - 3.6e-09 36.2 0.0 4.3e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KPI40478.1 - 1.7e-05 24.7 0.0 4.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain Acetyltransf_1 PF00583.25 KPI40479.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNA_pol_L_2 PF13656.6 KPI40479.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Sugar_tr PF00083.24 KPI40480.1 - 1.5e-86 291.0 26.8 1.8e-86 290.8 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40480.1 - 5.7e-25 88.0 45.1 3e-21 75.7 35.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rav1p_C PF12234.8 KPI40482.1 - 6.2e-59 200.0 0.1 1.4e-58 198.9 0.0 1.5 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 KPI40482.1 - 3.1 8.8 6.8 11 7.1 0.6 4.6 3 1 0 3 3 3 0 WD domain, G-beta repeat CPP1-like PF11833.8 KPI40483.1 - 0.013 15.2 2.4 2.4 7.8 0.1 2.6 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3147 PF11345.8 KPI40483.1 - 0.046 14.1 0.2 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Methyltransf_2 PF00891.18 KPI40484.1 - 2.9e-20 72.5 0.0 2.1e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KPI40484.1 - 0.0054 16.6 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MarR_2 PF12802.7 KPI40484.1 - 0.15 12.0 0.3 0.41 10.6 0.1 1.8 2 0 0 2 2 2 0 MarR family p450 PF00067.22 KPI40485.1 - 3.9e-61 207.2 0.0 4e-46 157.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MukF_C PF17193.4 KPI40485.1 - 0.085 13.0 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 MukF C-terminal domain DUF2156 PF09924.9 KPI40486.1 - 6.7e-29 100.8 0.0 8.7e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) UQ_con PF00179.26 KPI40487.1 - 8.7e-51 171.3 0.0 9.9e-51 171.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPI40487.1 - 0.0052 16.5 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPI40487.1 - 0.066 13.5 0.0 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain PAN_4 PF14295.6 KPI40488.1 - 0.067 13.1 7.9 0.034 14.1 3.6 2.6 2 0 0 2 2 2 0 PAN domain Asp PF00026.23 KPI40489.1 - 1.4e-52 179.1 0.0 1.8e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI40489.1 - 4.2e-12 46.7 0.9 4.9e-09 36.7 0.1 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KPI40489.1 - 0.022 14.6 0.1 0.58 9.9 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal ANAPC1 PF12859.7 KPI40490.1 - 4.7e-13 49.8 0.1 4.7e-13 49.8 0.1 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KPI40490.1 - 2.2e-07 30.9 3.9 0.00019 21.7 0.0 4.1 4 0 0 4 4 4 2 Proteasome/cyclosome repeat DUF3253 PF11625.8 KPI40491.1 - 4.9e-12 45.9 0.4 0.00032 20.8 0.0 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3253) Glyco_hydro_61 PF03443.14 KPI40492.1 - 2.3e-60 204.1 0.0 3.4e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KPI40492.1 - 5e-13 48.7 11.8 2.1e-12 46.7 11.8 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Rad60-SLD PF11976.8 KPI40493.1 - 3.8e-17 61.9 0.0 5.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KPI40493.1 - 3.1e-06 26.8 0.0 3.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF501 PF04417.12 KPI40494.1 - 0.0033 17.2 1.8 0.0069 16.2 1.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF501) DZR PF12773.7 KPI40494.1 - 0.0079 16.2 1.7 0.017 15.2 1.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon UPF0242 PF06785.11 KPI40494.1 - 0.016 15.3 13.2 0.03 14.4 12.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KPI40494.1 - 0.021 14.2 18.3 0.11 11.9 18.4 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IMD PF08397.11 KPI40494.1 - 0.18 11.2 4.6 0.27 10.6 4.6 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain HypA PF01155.19 KPI40494.1 - 0.25 11.4 0.9 0.61 10.1 0.9 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FapA PF03961.13 KPI40494.1 - 0.47 9.0 8.5 1.1 7.8 8.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF3450 PF11932.8 KPI40494.1 - 0.62 9.3 12.4 0.44 9.8 10.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KPI40494.1 - 2 8.9 25.2 0.091 13.2 12.4 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Zn-ribbon_8 PF09723.10 KPI40494.1 - 3.1 8.0 5.1 3.1 8.0 3.6 1.8 2 0 0 2 2 1 0 Zinc ribbon domain DUF4200 PF13863.6 KPI40494.1 - 7.6 7.0 18.7 0.78 10.2 13.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GIT_CC PF16559.5 KPI40494.1 - 7.9 6.4 8.8 0.66 9.9 3.4 2.1 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMCO5 PF14992.6 KPI40494.1 - 9 5.8 12.7 16 4.9 12.7 1.3 1 0 0 1 1 1 0 TMCO5 family TSC22 PF01166.18 KPI40494.1 - 9.4 6.6 7.9 4.2 7.7 1.7 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family TFIID-18kDa PF02269.16 KPI40495.1 - 7.5e-26 90.0 0.2 2.8e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Cadherin_C PF01049.17 KPI40495.1 - 0.009 16.4 1.3 0.021 15.1 1.3 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region TLP-20 PF06088.11 KPI40495.1 - 1.3 8.9 4.5 1.9 8.3 0.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NMT1 PF09084.11 KPI40496.1 - 2.5e-07 30.9 0.0 3e-06 27.3 0.0 2.1 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 KPI40496.1 - 6.5e-05 22.7 0.0 0.0017 18.1 0.0 2.2 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 KPI40496.1 - 0.04 13.4 0.0 0.2 11.0 0.0 2.0 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 CorA PF01544.18 KPI40498.1 - 9.2e-17 61.3 1.0 1.8e-16 60.4 1.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TMEM171 PF15471.6 KPI40498.1 - 0.0001 21.4 0.1 0.00016 20.7 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein family 171 SUR7 PF06687.12 KPI40498.1 - 0.14 11.8 1.6 0.47 10.0 0.8 1.9 2 0 0 2 2 2 0 SUR7/PalI family TMEM154 PF15102.6 KPI40498.1 - 4.9 7.0 5.2 22 5.0 0.3 2.9 2 1 1 3 3 3 0 TMEM154 protein family Glyco_tran_28_C PF04101.16 KPI40499.1 - 1.1e-13 51.5 0.2 3.5e-13 49.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KPI40499.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ferritin_2 PF13668.6 KPI40501.1 - 6.7e-38 130.0 0.4 1.2e-37 129.2 0.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 KPI40501.1 - 0.055 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) FLgD_tudor PF13861.6 KPI40501.1 - 1 9.7 4.8 1.7 8.9 2.2 2.6 2 0 0 2 2 2 0 FlgD Tudor-like domain ADH_zinc_N PF00107.26 KPI40502.1 - 1.6e-07 31.4 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI40502.1 - 0.00094 18.7 0.1 0.0018 17.8 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DUF3669 PF12417.8 KPI40504.1 - 9e-07 29.0 0.7 2.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Zinc finger protein F-box-like PF12937.7 KPI40505.1 - 0.012 15.5 2.0 0.46 10.4 0.1 2.7 3 0 0 3 3 3 0 F-box-like BTB PF00651.31 KPI40507.1 - 1.3e-12 47.9 0.0 6.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain NitrOD5 PF11537.8 KPI40507.1 - 8.1e-05 22.7 0.1 0.3 11.3 0.0 3.0 3 0 0 3 3 3 2 Nitrosopumilus output domain 5 Big_2 PF02368.18 KPI40508.1 - 0.18 11.7 12.5 0.55 10.2 2.1 3.7 3 1 1 4 4 4 0 Bacterial Ig-like domain (group 2) zf-CCCH PF00642.24 KPI40510.1 - 0.028 14.3 0.9 0.058 13.3 0.9 1.6 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAGE_N PF12440.8 KPI40511.1 - 1.2 9.8 9.8 2.3 8.9 9.8 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF515 PF04415.12 KPI40511.1 - 6.8 5.0 7.1 8.8 4.6 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FA_desaturase PF00487.24 KPI40514.1 - 3.3e-29 102.5 23.8 5.2e-29 101.9 23.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KPI40514.1 - 0.031 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) p450 PF00067.22 KPI40515.1 - 1.3e-59 202.2 0.0 2.2e-59 201.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_Mx PF15887.5 KPI40516.1 - 0.046 13.1 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Holin_9 PF16936.5 KPI40517.1 - 0.088 13.0 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Putative holin Acetyltransf_1 PF00583.25 KPI40518.1 - 1.5e-05 25.2 0.0 3.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI40518.1 - 3.9e-05 23.6 0.0 9.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI40518.1 - 0.0009 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3439 PF11921.8 KPI40518.1 - 0.14 12.2 8.2 0.32 11.0 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PLAC8 PF04749.17 KPI40519.1 - 2.6e-24 86.1 12.3 3.1e-24 85.8 12.3 1.1 1 0 0 1 1 1 1 PLAC8 family DUF1180 PF06679.12 KPI40520.1 - 0.023 15.1 2.8 0.023 15.1 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Acetyltransf_2 PF00797.17 KPI40521.1 - 2e-35 122.7 0.0 5.4e-35 121.3 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KPI40521.1 - 0.09 13.2 0.1 0.37 11.2 0.1 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily 4HB_MCP_1 PF12729.7 KPI40523.1 - 0.18 11.3 0.1 0.28 10.7 0.1 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction HemY_N PF07219.13 KPI40524.1 - 4 7.7 5.3 54 4.1 0.2 3.1 3 0 0 3 3 3 0 HemY protein N-terminus PEP-utilizers PF00391.23 KPI40525.1 - 0.028 14.1 0.3 0.12 12.1 0.3 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain Sugar_tr PF00083.24 KPI40526.1 - 2e-68 231.3 9.7 5.7e-67 226.5 9.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40526.1 - 1.8e-20 73.2 29.0 4.5e-19 68.6 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KPI40526.1 - 0.0021 17.2 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 PUCC protein MFS_2 PF13347.6 KPI40526.1 - 0.01 14.4 8.2 0.038 12.6 0.2 2.7 2 2 0 2 2 2 0 MFS/sugar transport protein NB-ARC PF00931.22 KPI40527.1 - 3.9e-06 26.3 0.0 8.1e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KPI40527.1 - 0.032 14.1 3.7 0.045 13.7 0.6 2.8 3 1 0 3 3 3 0 NACHT domain Peptidase_M27 PF01742.17 KPI40527.1 - 0.039 13.1 0.4 0.062 12.4 0.4 1.2 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease DUF1765 PF08578.10 KPI40528.1 - 6.9e-43 146.1 7.3 1.4e-42 145.1 7.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DUF3425 PF11905.8 KPI40529.1 - 5.7e-16 58.6 0.9 3.4e-15 56.1 0.7 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) CMS1 PF14617.6 KPI40530.1 - 5.4e-62 209.4 0.1 6.4e-62 209.2 0.1 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KPI40530.1 - 2.2e-06 27.6 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pyr_redox_2 PF07992.14 KPI40530.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KPI40531.1 - 5.1e-61 206.8 0.0 6.3e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KPI40532.1 - 0.0021 18.1 2.0 0.0037 17.3 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1918 PF08940.11 KPI40532.1 - 0.074 12.7 0.3 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Zn_clus PF00172.18 KPI40533.1 - 4.1e-06 26.8 11.3 7.1e-06 26.1 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATR13 PF16829.5 KPI40533.1 - 0.039 14.3 0.1 0.082 13.3 0.1 1.5 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector DUF3524 PF12038.8 KPI40533.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) PRP3 PF08572.10 KPI40536.1 - 2.2e-66 223.8 1.7 2.2e-66 223.8 1.7 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KPI40536.1 - 5.6e-46 156.3 1.2 1.3e-45 155.1 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) F-box PF00646.33 KPI40537.1 - 3.9e-06 26.6 1.0 9.8e-06 25.3 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPI40537.1 - 0.00045 20.0 2.5 0.00063 19.6 0.5 2.4 2 0 0 2 2 2 1 F-box-like ATP-synt PF00231.19 KPI40537.1 - 0.098 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 ATP synthase MFS_1 PF07690.16 KPI40538.1 - 7.3e-40 137.0 27.9 7.3e-40 137.0 27.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 KPI40538.1 - 2.2 8.6 8.1 0.13 12.5 1.7 2.3 2 1 1 3 3 3 0 Stage V sporulation protein AB 5_nucleotid_C PF02872.18 KPI40539.1 - 6.6e-24 84.9 0.0 1.5e-22 80.5 0.0 2.2 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KPI40539.1 - 0.001 19.6 0.0 0.0063 17.0 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_47 PF01532.20 KPI40541.1 - 2.1e-172 574.2 0.0 2.5e-172 573.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.6 KPI40541.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) 4HBT PF03061.22 KPI40542.1 - 6.6e-12 45.6 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RNase_H2-Ydr279 PF09468.10 KPI40543.1 - 1.5e-33 116.2 1.5 4.4e-33 114.7 0.0 2.2 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KPI40543.1 - 4.3e-20 71.8 0.1 9.7e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DUF4710 PF15828.5 KPI40543.1 - 0.24 11.5 4.2 0.65 10.2 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) MFS_1 PF07690.16 KPI40544.1 - 1.1e-22 80.4 19.1 1.1e-22 80.4 19.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI40544.1 - 0.00012 20.6 4.8 0.00012 20.6 4.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ACOX PF01756.19 KPI40545.1 - 1.8e-39 135.2 0.0 8.3e-39 133.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KPI40545.1 - 4.5e-21 75.7 1.4 4.5e-21 75.7 1.4 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPI40545.1 - 2.4e-09 37.2 0.0 5.8e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MR_MLE_C PF13378.6 KPI40546.1 - 3.4e-48 164.1 0.3 4.4e-48 163.8 0.3 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI40546.1 - 0.00035 20.8 0.1 0.0029 17.8 0.1 2.2 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HATPase_c PF02518.26 KPI40547.1 - 3.1e-26 92.1 0.0 1.7e-25 89.7 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI40547.1 - 1.3e-23 83.3 0.1 2.8e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KPI40547.1 - 7.1e-16 58.0 0.1 2.3e-15 56.4 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MFS_1 PF07690.16 KPI40549.1 - 2.3e-36 125.5 26.6 2.9e-35 121.9 25.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily XRN_M PF17846.1 KPI40550.1 - 2e-142 475.3 1.2 9.3e-141 469.8 0.0 2.8 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KPI40550.1 - 6.2e-98 327.0 0.0 6.2e-98 327.0 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KPI40550.1 - 0.0022 18.0 3.3 0.0043 17.1 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KPI40550.1 - 0.0065 16.3 2.3 0.014 15.2 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KPI40550.1 - 0.24 11.4 1.2 0.43 10.6 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Beta-lactamase PF00144.24 KPI40551.1 - 6.4e-31 107.8 2.2 2.4e-30 105.9 2.2 1.9 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KPI40551.1 - 0.018 14.6 0.0 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KPI40551.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Reticulon PF02453.17 KPI40552.1 - 2.3e-30 105.6 3.3 3.1e-30 105.2 3.3 1.2 1 0 0 1 1 1 1 Reticulon SMBP PF16785.5 KPI40552.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Small metal-binding protein DAGK_prokar PF01219.19 KPI40552.1 - 0.81 9.6 3.4 1.9 8.4 0.3 2.4 2 1 0 2 2 2 0 Prokaryotic diacylglycerol kinase VID27 PF08553.10 KPI40553.1 - 3.6e-152 506.5 0.0 6.3e-86 288.6 0.0 2.2 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KPI40553.1 - 8.8e-74 247.1 1.6 8.8e-74 247.1 1.6 3.0 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KPI40553.1 - 3e-43 146.5 2.2 1e-42 144.8 1.0 2.2 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 KPI40553.1 - 0.018 15.3 3.3 0.052 13.8 1.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Pro_isomerase PF00160.21 KPI40554.1 - 5e-47 160.1 0.2 9.5e-47 159.2 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 KPI40554.1 - 6e-06 25.9 6.7 5.4e-05 22.8 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KPI40554.1 - 1.3e-05 24.9 12.1 5.4e-05 23.0 0.6 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI40554.1 - 0.0001 22.2 0.4 0.0001 22.2 0.4 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPI40554.1 - 0.00083 20.0 6.9 0.0021 18.7 1.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPI40554.1 - 0.0017 18.5 2.0 0.012 15.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPI40554.1 - 0.0026 18.0 3.9 0.069 13.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPI40554.1 - 0.0043 16.7 11.2 0.24 11.1 0.8 3.6 3 1 1 4 4 4 2 TPR repeat TPR_6 PF13174.6 KPI40554.1 - 0.0056 17.2 1.7 0.36 11.6 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPI40554.1 - 0.037 14.7 8.2 0.12 13.0 1.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPI40554.1 - 0.072 13.6 4.4 1.2 9.7 0.8 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 KPI40554.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) ADH_N PF08240.12 KPI40555.1 - 7e-29 99.9 2.9 9.4e-29 99.5 2.9 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HEAT_2 PF13646.6 KPI40557.1 - 0.014 15.8 0.5 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 HEAT repeats MAGI_u5 PF16666.5 KPI40557.1 - 0.19 11.9 7.6 0.45 10.7 7.6 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI DUF382 PF04037.13 KPI40558.1 - 4.3e-60 201.5 2.1 4.3e-60 201.5 2.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KPI40558.1 - 2.7e-21 75.2 3.3 5.8e-21 74.1 3.3 1.6 1 0 0 1 1 1 1 PSP DUF3433 PF11915.8 KPI40559.1 - 4.5e-14 52.7 1.2 4.5e-14 52.7 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) UBM PF14377.6 KPI40560.1 - 0.013 14.9 0.9 0.027 13.9 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin binding region F-box-like PF12937.7 KPI40560.1 - 0.055 13.4 0.1 0.25 11.2 0.1 2.1 1 1 0 1 1 1 0 F-box-like DUF1993 PF09351.10 KPI40561.1 - 8.1e-50 169.1 0.0 9.1e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Peptidase_C1_2 PF03051.15 KPI40562.1 - 1.2e-149 498.8 0.2 7.1e-119 397.5 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KPI40562.1 - 2.1e-07 31.2 0.0 0.018 15.1 0.0 2.8 2 1 0 2 2 2 2 Papain family cysteine protease Peptidase_M36 PF02128.15 KPI40562.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) TGS PF02824.21 KPI40562.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 TGS domain Chitin_synth_1 PF01644.17 KPI40563.1 - 1.4e-74 249.5 0.2 2.1e-74 248.9 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KPI40563.1 - 5.7e-30 103.1 0.1 1.1e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPI40563.1 - 6.1e-22 77.9 2.2 3.7e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPI40563.1 - 1.4e-09 38.2 0.1 1.4e-09 38.2 0.1 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 NAD_binding_2 PF03446.15 KPI40564.1 - 3.3e-33 115.1 0.0 4.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI40564.1 - 7.6e-18 64.9 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KPI40564.1 - 0.00024 21.6 0.1 0.0013 19.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KPI40564.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DBR1 PF05011.13 KPI40564.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Sugar_tr PF00083.24 KPI40565.1 - 5.4e-54 183.8 20.6 6.8e-50 170.2 15.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI40565.1 - 4.4e-13 48.9 38.9 1e-11 44.4 30.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Het-C PF07217.11 KPI40566.1 - 1.5e-116 390.2 0.0 2.5e-116 389.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DJ-1_PfpI PF01965.24 KPI40567.1 - 3.2e-05 23.8 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2_2 PF12756.7 KPI40569.1 - 5.1e-06 26.8 3.5 6e-05 23.3 0.2 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPI40569.1 - 7.7e-06 26.3 3.9 0.11 13.3 0.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI40569.1 - 0.0075 16.7 6.4 0.073 13.6 0.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KPI40569.1 - 0.012 15.9 0.3 0.031 14.5 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KPI40569.1 - 0.015 15.8 0.5 0.038 14.4 0.5 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain ACP PF06857.11 KPI40569.1 - 0.13 12.5 0.0 20 5.5 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) zf-C2H2_6 PF13912.6 KPI40569.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KPI40569.1 - 0.77 9.6 3.6 20 5.0 1.6 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KPI40569.1 - 0.95 9.9 3.2 5.3 7.6 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sugar_tr PF00083.24 KPI40571.1 - 6.8e-21 74.7 25.5 6.3e-13 48.4 9.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MUG113 PF13455.6 KPI40571.1 - 0.11 13.2 0.1 0.28 11.9 0.1 1.6 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 Amb_V_allergen PF03913.13 KPI40572.1 - 0.2 11.6 5.3 2.6 8.1 4.0 3.1 3 1 0 3 3 3 0 Amb V Allergen Abhydrolase_6 PF12697.7 KPI40573.1 - 1.8e-11 45.1 0.1 2.2e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KPI40573.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans_2 PF11951.8 KPI40574.1 - 0.048 12.5 0.0 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain BTB PF00651.31 KPI40576.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Asp_protease_2 PF13650.6 KPI40577.1 - 1.7e-07 31.8 0.0 0.00049 20.7 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI40577.1 - 0.00087 19.8 0.0 0.14 12.8 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KPI40577.1 - 0.0065 16.3 0.7 1.2 8.9 0.0 3.1 2 1 1 3 3 3 1 Putative peptidase (DUF1758) RVP PF00077.20 KPI40577.1 - 0.023 15.0 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease MFS_1 PF07690.16 KPI40579.1 - 1.7e-24 86.4 27.8 1.7e-24 86.4 27.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 KPI40579.1 - 0.084 13.2 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Mannosidase_ig PF17786.1 KPI40580.1 - 3.9e-17 62.6 0.3 1.4e-16 60.8 0.3 2.1 1 1 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KPI40580.1 - 3.1e-08 33.2 0.0 9.7e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KPI40580.1 - 1.1e-07 32.5 0.1 4.2e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KPI40580.1 - 0.0017 17.5 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Vps51 PF08700.11 KPI40581.1 - 1.8e-20 72.8 0.0 3.5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KPI40581.1 - 0.053 12.2 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family CEND1 PF15677.5 KPI40581.1 - 0.82 10.2 9.4 1.5 9.3 9.4 1.4 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Ist1 PF03398.14 KPI40582.1 - 1.2e-48 165.2 2.3 1.5e-48 164.8 2.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GFA PF04828.14 KPI40583.1 - 4.3e-05 23.8 0.8 0.37 11.1 0.2 3.0 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme MafB19-deam PF14437.6 KPI40584.1 - 2.8e-05 23.9 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KPI40584.1 - 0.00026 20.8 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DAO PF01266.24 KPI40585.1 - 3.6e-28 99.1 4.7 6.5e-15 55.6 0.1 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase MFS_1 PF07690.16 KPI40586.1 - 5.7e-34 117.6 19.8 7.5e-34 117.2 18.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily EptA_B_N PF08019.12 KPI40586.1 - 0.12 12.2 2.8 4 7.3 0.1 3.3 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB HAD_SAK_1 PF10307.9 KPI40587.1 - 1e-65 221.3 0.0 1.9e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins BLOC1_2 PF10046.9 KPI40588.1 - 0.0081 16.4 0.8 0.017 15.4 0.8 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 KPI40588.1 - 0.03 14.7 3.7 0.03 14.7 3.7 1.6 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) GIT_CC PF16559.5 KPI40588.1 - 0.031 14.1 2.8 0.031 14.1 2.8 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FTA4 PF13093.6 KPI40588.1 - 0.039 13.8 2.4 0.071 13.0 2.4 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Occludin_ELL PF07303.13 KPI40588.1 - 0.048 14.4 0.4 0.088 13.5 0.4 1.4 1 0 0 1 1 1 0 Occludin homology domain Zn-ribbon_8 PF09723.10 KPI40588.1 - 0.051 13.7 0.5 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HMMR_N PF15905.5 KPI40588.1 - 0.067 12.7 3.9 0.14 11.6 3.9 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GATA PF00320.27 KPI40588.1 - 0.1 12.2 4.9 0.19 11.3 4.9 1.4 1 0 0 1 1 1 0 GATA zinc finger NRBF2 PF08961.10 KPI40588.1 - 0.15 11.6 5.6 0.23 11.0 2.6 2.3 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF1272 PF06906.11 KPI40588.1 - 0.18 11.9 0.8 22 5.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) YabA PF06156.13 KPI40588.1 - 0.19 12.4 5.3 0.19 12.4 2.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA MCC-bdg_PDZ PF10506.9 KPI40588.1 - 0.19 11.8 4.8 0.064 13.3 1.5 1.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ZapB PF06005.12 KPI40588.1 - 0.26 11.7 13.7 0.052 14.0 8.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 KPI40588.1 - 0.62 10.3 6.5 0.89 9.8 3.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 KPI40588.1 - 1.3 9.4 11.8 0.11 12.8 2.1 3.6 3 1 2 5 5 5 0 TSC-22/dip/bun family Cupin_8 PF13621.6 KPI40589.1 - 2e-34 119.5 0.0 3.2e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KPI40589.1 - 1.1e-07 31.7 0.2 8.5e-06 25.4 0.0 2.6 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 KPI40589.1 - 0.00014 22.3 0.0 0.00044 20.7 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KPI40589.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Iso_dh PF00180.20 KPI40590.1 - 1.6e-69 234.7 0.0 2e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHMI PF02962.15 KPI40590.1 - 0.043 14.2 0.2 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 5-carboxymethyl-2-hydroxymuconate isomerase Opy2 PF09463.10 KPI40592.1 - 8.5e-11 42.0 21.1 1.3e-10 41.4 21.1 1.3 1 0 0 1 1 1 1 Opy2 protein DUF4381 PF14316.6 KPI40592.1 - 0.084 13.1 0.7 0.18 12.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Adeno_E3_CR2 PF02439.15 KPI40592.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MFS_1 PF07690.16 KPI40593.1 - 0.011 14.7 11.8 0.22 10.4 10.5 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily MFS_1 PF07690.16 KPI40594.1 - 8.2e-24 84.2 53.4 8.5e-17 61.1 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4087 PF13316.6 KPI40596.1 - 0.21 12.1 1.6 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) RTA1 PF04479.13 KPI40597.1 - 1.5e-61 207.7 12.8 2e-61 207.2 12.8 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.16 KPI40598.1 - 5.8e-27 94.5 31.8 1.6e-26 93.1 31.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40598.1 - 3.3e-06 26.2 13.0 3.3e-06 26.2 13.0 1.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KPI40598.1 - 0.00064 18.1 1.7 0.00064 18.1 1.7 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Lectin_N PF03954.14 KPI40598.1 - 0.18 11.6 0.4 0.48 10.2 0.1 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3040 PF11239.8 KPI40598.1 - 0.21 11.9 0.0 0.21 11.9 0.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) DUF1700 PF08006.11 KPI40598.1 - 0.72 9.4 11.0 0.029 13.9 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) AMP-binding PF00501.28 KPI40600.1 - 4e-78 262.9 0.0 5.2e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ECH_1 PF00378.20 KPI40600.1 - 1.9e-44 151.9 0.0 2.9e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI40600.1 - 2.3e-29 103.0 0.0 4.1e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding_C PF13193.6 KPI40600.1 - 2.8e-05 25.0 0.1 0.00018 22.4 0.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 KPI40601.1 - 1.7e-07 31.2 13.3 4.5e-07 29.9 13.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 KPI40601.1 - 2.1 8.7 7.2 4.3 7.8 7.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) AA_permease PF00324.21 KPI40602.1 - 4e-121 404.9 38.2 4.8e-121 404.7 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI40602.1 - 4.6e-32 111.4 42.0 6.2e-32 111.0 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.19 KPI40603.1 - 1.4e-62 211.8 0.0 2e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI40603.1 - 3.5e-30 105.4 0.0 6.3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI40603.1 - 0.00038 19.6 0.1 0.00054 19.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KPI40603.1 - 0.0091 15.3 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KPI40603.1 - 0.016 14.3 0.0 3 6.8 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain F-box-like PF12937.7 KPI40604.1 - 0.0028 17.5 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like Not3 PF04065.15 KPI40605.1 - 2.5e-68 230.0 25.6 4e-68 229.3 25.6 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KPI40605.1 - 5.4e-41 139.7 13.1 1.6e-40 138.2 13.1 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 KPI40605.1 - 0.016 15.0 4.0 0.039 13.8 4.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 KPI40605.1 - 0.018 15.4 4.9 0.018 15.4 4.9 2.6 2 0 0 2 2 2 0 Syntaxin-like protein RIX1 PF08167.12 KPI40605.1 - 0.41 10.4 1.7 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis PilJ PF13675.6 KPI40605.1 - 0.66 10.0 5.2 0.38 10.8 0.3 2.8 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term LMWPc PF01451.21 KPI40606.1 - 3.1e-37 128.1 0.0 3.5e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF4912 PF16258.5 KPI40607.1 - 0.072 13.3 0.1 4.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4912) DNA_pol_phi PF04931.13 KPI40607.1 - 0.096 10.8 1.7 0.12 10.4 1.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KPI40607.1 - 0.11 12.2 1.3 0.12 12.1 1.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PrmA PF06325.13 KPI40608.1 - 2.6e-11 43.5 0.1 6.6e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KPI40608.1 - 3.5e-11 43.7 0.1 2.5e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40608.1 - 1e-09 38.4 0.0 2e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40608.1 - 1.8e-09 38.1 0.0 1.4e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KPI40608.1 - 2.2e-06 27.7 0.0 5.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI40608.1 - 2.5e-06 27.1 0.1 5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KPI40608.1 - 5.9e-06 26.2 0.1 1.7e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_23 PF13489.6 KPI40608.1 - 7.9e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI40608.1 - 0.00093 19.9 0.0 0.002 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPI40608.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KPI40608.1 - 0.0027 16.7 0.0 0.0047 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 KPI40608.1 - 0.0038 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 KPI40608.1 - 0.0083 15.6 0.1 0.049 13.0 0.1 1.9 1 1 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 KPI40608.1 - 0.028 15.4 0.1 0.12 13.4 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KPI40608.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Cons_hypoth95 PF03602.15 KPI40608.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 KPI40608.1 - 0.15 11.3 0.2 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Amidase PF01425.21 KPI40609.1 - 3.7e-27 95.4 1.3 3.7e-27 95.4 1.3 2.5 3 1 1 4 4 4 1 Amidase CFEM PF05730.11 KPI40610.1 - 3.2e-09 36.7 10.9 5e-09 36.1 10.9 1.3 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 KPI40610.1 - 7.4e-05 22.9 0.9 0.00017 21.7 0.1 2.0 2 0 0 2 2 2 1 Podoplanin TMEM154 PF15102.6 KPI40610.1 - 0.0076 16.2 1.4 0.014 15.3 0.1 2.1 2 1 0 2 2 2 1 TMEM154 protein family CoA_trans PF01144.23 KPI40611.1 - 1.8e-91 305.4 1.1 1.8e-55 187.7 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KPI40611.1 - 2.5e-06 27.5 0.1 5.6e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SSP160 PF06933.11 KPI40612.1 - 0.073 11.3 15.3 0.09 11.0 15.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 KPI40612.1 - 2.4 6.0 3.7 3 5.7 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGC-24 PF05283.11 KPI40612.1 - 4.4 7.7 11.9 7.8 7.0 11.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KPI40612.1 - 7.5 4.6 8.9 9.2 4.3 8.9 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cupin_2 PF07883.11 KPI40614.1 - 1.2e-08 34.5 0.0 2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPI40614.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) PapD_C PF02753.17 KPI40614.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain HMG_box PF00505.19 KPI40616.1 - 1.5e-21 76.6 0.5 3e-21 75.6 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPI40616.1 - 1.6e-06 28.6 0.9 2.9e-06 27.8 0.3 1.8 2 0 0 2 2 2 1 HMG-box domain DUF3527 PF12043.8 KPI40616.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) HMGL-like PF00682.19 KPI40617.1 - 2e-31 109.6 0.0 2.7e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 HMGL-like MFS_1 PF07690.16 KPI40618.1 - 5.3e-29 101.2 30.1 5.3e-29 101.2 30.1 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily NSs PF11073.8 KPI40618.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Complex1_LYR_2 PF13233.6 KPI40619.1 - 2.1e-23 82.9 0.1 2.5e-23 82.6 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KPI40619.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) GluR_Homer-bdg PF10606.9 KPI40619.1 - 0.053 13.7 0.3 0.083 13.1 0.3 1.3 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor BTB PF00651.31 KPI40620.1 - 2.5e-09 37.4 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CDC45 PF02724.14 KPI40621.1 - 0.73 8.1 6.2 0.95 7.7 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SNN_linker PF09050.10 KPI40621.1 - 1.8 8.4 6.2 4 7.3 6.2 1.6 1 0 0 1 1 1 0 Stannin unstructured linker B12D PF06522.11 KPI40623.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Methyltransf_16 PF10294.9 KPI40624.1 - 1.5e-18 67.1 0.0 2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KPI40624.1 - 0.00041 19.8 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KPI40624.1 - 0.00042 20.0 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KPI40624.1 - 0.00061 20.5 0.1 0.0024 18.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI40624.1 - 0.0058 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI40624.1 - 0.019 15.6 0.0 0.1 13.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Sod_Fe_C PF02777.18 KPI40625.1 - 4.6e-36 123.1 0.3 4.6e-36 123.1 0.3 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KPI40625.1 - 6.5e-29 100.2 1.7 1.1e-28 99.5 1.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Trp_syntA PF00290.20 KPI40626.1 - 1.2e-88 296.3 0.0 2.2e-88 295.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KPI40626.1 - 3.2e-46 158.1 0.6 5.2e-46 157.4 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme STN PF07660.14 KPI40626.1 - 0.67 9.8 2.4 5.7 6.8 0.1 2.9 3 0 0 3 3 3 0 Secretin and TonB N terminus short domain IBN_N PF03810.19 KPI40627.1 - 5.6e-14 51.8 1.4 1.8e-12 47.0 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KPI40627.1 - 1.1e-09 37.6 0.1 4.7e-09 35.5 0.1 2.1 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 KPI40627.1 - 0.00043 20.4 0.1 0.036 14.1 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HPPK PF01288.20 KPI40627.1 - 0.072 13.6 0.0 0.42 11.1 0.1 2.3 3 0 0 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) GRIP PF01465.20 KPI40627.1 - 0.13 12.2 0.3 0.87 9.5 0.3 2.5 1 1 1 2 2 2 0 GRIP domain DCB PF16213.5 KPI40627.1 - 0.16 11.6 0.4 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 RTP1_C1 PF10363.9 KPI40627.1 - 0.2 11.8 1.7 0.8 9.9 0.1 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Fungal_trans PF04082.18 KPI40628.1 - 1.1e-07 31.2 0.7 1.8e-07 30.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.8 KPI40630.1 - 3.3e-05 23.9 0.1 0.0001 22.2 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Vezatin PF12632.7 KPI40631.1 - 2.4e-43 148.5 0.1 3.2e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes p450 PF00067.22 KPI40632.1 - 5.5e-49 167.2 0.0 6.6e-40 137.2 0.0 2.1 1 1 0 2 2 2 2 Cytochrome P450 DUF1295 PF06966.12 KPI40633.1 - 1.6e-42 145.6 0.2 8.8e-41 140.0 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KPI40633.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KPI40633.1 - 0.024 15.1 0.0 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KPI40633.1 - 0.067 13.6 0.0 0.43 11.0 0.0 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase MFS_1 PF07690.16 KPI40635.1 - 6.3e-20 71.4 21.0 1.4e-19 70.3 21.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40635.1 - 2.2e-05 23.5 4.6 2.2e-05 23.5 4.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KPI40635.1 - 0.9 7.7 4.6 6.2 5.0 4.6 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HMMR_N PF15905.5 KPI40636.1 - 0.15 11.5 16.5 0.67 9.4 15.6 2.3 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HOOK PF05622.12 KPI40636.1 - 0.23 9.5 19.0 0.13 10.3 16.6 1.6 2 0 0 2 2 2 0 HOOK protein ATG16 PF08614.11 KPI40636.1 - 0.29 11.4 23.1 0.33 11.1 13.7 3.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KPI40636.1 - 1.1 9.8 25.8 1.1e+02 3.3 3.2 3.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 KPI40636.1 - 1.5 8.9 20.7 0.71 10.0 17.1 2.2 2 1 0 2 2 2 0 Tropomyosin like Phage_GP20 PF06810.11 KPI40636.1 - 1.6 8.6 9.1 0.25 11.1 2.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 UPF0242 PF06785.11 KPI40636.1 - 3 7.9 25.1 32 4.5 25.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KPI40636.1 - 3.3 5.5 7.1 4.6 5.0 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family JIP_LZII PF16471.5 KPI40636.1 - 4 7.7 12.6 3.6 7.8 2.0 3.5 3 2 1 4 4 4 0 JNK-interacting protein leucine zipper II Fez1 PF06818.15 KPI40636.1 - 6.7 7.1 20.1 2.3 8.7 17.2 1.6 2 0 0 2 2 2 0 Fez1 ERM PF00769.19 KPI40636.1 - 7.3 6.3 21.7 18 5.0 21.8 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HALZ PF02183.18 KPI40637.1 - 5.7e-07 29.7 3.8 0.00043 20.4 0.2 2.9 3 0 0 3 3 3 2 Homeobox associated leucine zipper Nup54 PF13874.6 KPI40637.1 - 0.0013 18.8 3.1 0.0027 17.8 3.1 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 bZIP_1 PF00170.21 KPI40637.1 - 0.0023 18.0 10.5 0.0047 17.0 0.4 2.9 3 0 0 3 3 3 2 bZIP transcription factor NRBF2 PF08961.10 KPI40637.1 - 0.012 15.2 2.2 0.012 15.2 2.2 2.6 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 KPI40637.1 - 0.019 15.4 9.0 0.44 11.0 0.3 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Shugoshin_N PF07558.11 KPI40637.1 - 0.19 11.6 4.9 0.14 12.0 0.5 2.6 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Atg14 PF10186.9 KPI40637.1 - 0.22 10.6 2.7 0.46 9.5 2.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KPI40637.1 - 0.29 10.9 6.3 2.6 7.9 0.2 2.8 3 0 0 3 3 3 0 Septum formation initiator BLOC1_2 PF10046.9 KPI40637.1 - 0.41 11.0 3.3 1.1 9.6 0.4 2.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 KPI40637.1 - 0.49 10.6 3.9 6.6 7.0 0.4 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 KPI40637.1 - 0.71 10.2 7.3 0.41 11.0 0.3 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Prefoldin_2 PF01920.20 KPI40637.1 - 1.9 8.5 5.3 2.5 8.1 1.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Tropomyosin_1 PF12718.7 KPI40637.1 - 1.9 8.6 13.5 0.036 14.2 6.2 2.0 3 0 0 3 3 2 0 Tropomyosin like YabA PF06156.13 KPI40637.1 - 2.8 8.6 7.5 0.6 10.8 0.2 2.8 3 1 1 4 4 3 0 Initiation control protein YabA bZIP_2 PF07716.15 KPI40637.1 - 9.2 6.4 14.1 1.3 9.2 0.2 3.1 3 0 0 3 3 2 0 Basic region leucine zipper Neur_chan_memb PF02932.16 KPI40638.1 - 0.34 10.9 0.3 0.4 10.7 0.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 KPI40639.1 - 4.7e-19 68.5 27.3 4.7e-19 68.5 27.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40639.1 - 0.0014 17.6 10.5 0.0014 17.6 10.5 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter PIG-Y PF15159.6 KPI40639.1 - 0.031 15.2 0.2 0.031 15.2 0.2 3.8 2 1 3 5 5 5 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Adeno_GP19K PF04881.13 KPI40639.1 - 0.41 10.6 2.9 2 8.4 0.2 3.1 4 0 0 4 4 4 0 Adenovirus GP19K OATP PF03137.20 KPI40639.1 - 1.2 7.4 16.1 0.32 9.2 1.9 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Gemini_mov PF01708.16 KPI40639.1 - 1.6 8.5 4.8 0.33 10.8 0.7 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein PRA1 PF03208.19 KPI40639.1 - 2.4 7.8 11.5 0.22 11.1 0.5 3.5 3 0 0 3 3 3 0 PRA1 family protein GFO_IDH_MocA PF01408.22 KPI40640.1 - 2.2e-18 67.2 0.0 3.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PQQ_3 PF13570.6 KPI40640.1 - 0.048 14.2 0.1 0.32 11.5 0.1 2.4 2 0 0 2 2 2 0 PQQ-like domain FYVE PF01363.21 KPI40641.1 - 5.4e-23 80.9 21.3 7.7e-17 61.2 3.2 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KPI40641.1 - 1.7e-18 66.0 0.6 5.1e-18 64.5 0.6 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 KPI40641.1 - 0.0001 22.5 8.6 0.056 13.8 0.1 2.9 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KPI40641.1 - 0.00098 19.2 5.4 0.00098 19.2 5.4 3.9 3 1 1 4 4 4 1 AN1-like Zinc finger zf-C2H2_2 PF12756.7 KPI40641.1 - 0.0051 17.1 6.0 0.076 13.4 0.0 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KPI40641.1 - 0.028 14.4 0.4 0.028 14.4 0.4 3.5 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KPI40641.1 - 0.061 13.6 3.1 4.9 7.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon YqaH PF17448.2 KPI40641.1 - 0.1 12.9 0.2 0.23 11.8 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like zf-C2H2_4 PF13894.6 KPI40641.1 - 1.2 10.2 0.0 1.2 10.2 0.0 5.1 5 1 0 5 5 5 0 C2H2-type zinc finger Rxt3 PF08642.10 KPI40642.1 - 6.2e-27 94.9 0.0 6e-26 91.7 0.0 2.6 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KPI40642.1 - 5.2e-06 26.5 0.0 9.1e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 LCCL domain HET PF06985.11 KPI40643.1 - 5.1e-29 101.5 0.7 1e-28 100.5 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SAPS PF04499.15 KPI40644.1 - 1.5e-70 238.4 3.7 1.6e-70 238.3 0.2 2.0 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Ribonuclease_T2 PF00445.18 KPI40645.1 - 1.2e-33 116.9 0.2 1.6e-33 116.5 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family FMO-like PF00743.19 KPI40645.1 - 0.2 10.1 0.2 0.28 9.6 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_4 PF07993.12 KPI40647.1 - 0.019 14.2 0.0 5 6.2 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 KPI40647.1 - 0.037 13.5 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Phage_holin_7_1 PF16081.5 KPI40648.1 - 0.075 13.2 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family TSSC4 PF15264.6 KPI40648.1 - 0.46 10.7 3.6 2.9 8.2 0.9 3.0 3 0 0 3 3 3 0 Tumour suppressing sub-chromosomal transferable candidate 4 NTF2 PF02136.20 KPI40649.1 - 0.16 12.5 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain V-SNARE_C PF12352.8 KPI40650.1 - 1.4e-17 63.7 2.8 1.4e-17 63.7 2.8 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KPI40650.1 - 6e-15 55.4 3.2 6e-15 55.4 3.2 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KPI40650.1 - 0.15 12.0 3.6 2.3 8.2 0.0 2.8 2 1 0 2 2 2 0 Sec20 DUF1542 PF07564.11 KPI40650.1 - 0.5 10.5 3.9 0.18 11.9 0.8 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) PilJ PF13675.6 KPI40650.1 - 1.2 9.2 9.3 0.36 10.9 1.1 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3500 PF12006.8 KPI40651.1 - 1.6e-77 260.9 0.0 3e-52 178.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3500) Utp14 PF04615.13 KPI40652.1 - 6.9e-182 606.9 57.9 6.9e-182 606.9 57.9 2.4 1 1 1 2 2 2 1 Utp14 protein Glyco_hydro81C PF17652.1 KPI40652.1 - 7.2e-155 515.5 6.7 1e-154 515.0 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KPI40652.1 - 1e-103 346.9 0.8 2e-103 346.0 0.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Alpha-amylase PF00128.24 KPI40653.1 - 1.8e-20 73.8 0.0 3e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KPI40653.1 - 0.033 12.4 0.2 0.97 7.5 0.0 2.6 4 0 0 4 4 4 0 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KPI40653.1 - 0.065 13.4 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) DUF1992 PF09350.10 KPI40654.1 - 3.7e-20 71.8 0.4 3.7e-20 71.8 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) AMP-binding_C_2 PF14535.6 KPI40654.1 - 0.19 12.1 2.2 0.59 10.5 0.1 2.8 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain DUF3437 PF11919.8 KPI40654.1 - 1.9 8.5 4.0 11 6.0 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Sulfate_transp PF00916.20 KPI40656.1 - 3.1e-80 269.8 9.5 4.4e-80 269.3 9.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPI40656.1 - 2e-16 59.7 0.0 3.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KPI40656.1 - 0.0003 21.1 0.0 0.0032 17.8 0.0 2.5 2 1 0 2 2 2 1 STAS domain IstB_IS21 PF01695.17 KPI40656.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Serinc PF03348.15 KPI40657.1 - 1.4e-148 495.4 13.2 1.6e-148 495.2 13.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) AC_N PF16214.5 KPI40657.1 - 0.86 8.7 3.2 1.6 7.8 3.2 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region FMO-like PF00743.19 KPI40658.1 - 8.7e-19 67.3 0.0 2.1e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI40658.1 - 7.7e-09 35.7 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI40658.1 - 1.6e-06 27.6 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI40658.1 - 8.8e-06 25.1 0.0 0.0014 17.8 0.0 2.8 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI40658.1 - 0.02 14.9 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI40658.1 - 0.079 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FCD PF07729.12 KPI40658.1 - 0.18 12.2 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 FCD domain Choline_transpo PF04515.12 KPI40659.1 - 9.4e-79 264.9 24.8 9.4e-79 264.9 24.8 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KPI40659.1 - 0.26 12.0 7.0 0.7 10.5 7.0 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PBP_N PF17093.5 KPI40659.1 - 3.7 7.8 6.5 0.25 11.6 0.4 2.1 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Glyco_hydro_72 PF03198.14 KPI40660.1 - 2.4e-136 454.1 6.1 2.9e-136 453.8 6.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KPI40660.1 - 1.9e-09 37.3 0.5 5.1e-09 36.0 0.5 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GYF PF02213.16 KPI40662.1 - 6.6e-18 64.1 0.3 4.2e-17 61.5 0.2 2.3 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 KPI40662.1 - 0.059 13.2 0.1 0.27 11.1 0.1 2.3 1 0 0 1 1 1 0 GYF domain 2 Nop53 PF07767.11 KPI40662.1 - 1.1 8.6 11.0 0.087 12.2 5.5 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) TPR_MLP1_2 PF07926.12 KPI40663.1 - 2e-33 115.2 29.6 2e-33 115.2 29.6 18.0 6 4 9 17 17 17 3 TPR/MLP1/MLP2-like protein Filament PF00038.21 KPI40663.1 - 0.00068 19.3 37.2 0.00068 19.3 37.2 12.9 4 2 6 11 11 11 2 Intermediate filament protein Atg14 PF10186.9 KPI40663.1 - 0.0034 16.5 7.6 0.0034 16.5 7.6 13.5 4 2 8 13 13 13 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2353 PF09789.9 KPI40663.1 - 0.0039 16.6 20.5 0.0039 16.6 20.5 11.6 4 2 8 12 12 12 2 Uncharacterized coiled-coil protein (DUF2353) Mto2_bdg PF12808.7 KPI40663.1 - 0.0063 16.8 3.9 0.0063 16.8 3.9 12.5 14 3 1 16 16 16 1 Micro-tubular organiser Mto1 C-term Mto2-binding region YkuD PF03734.14 KPI40663.1 - 0.052 14.0 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain KH_1 PF00013.29 KPI40664.1 - 1.6e-48 162.4 7.2 3.3e-16 58.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KPI40664.1 - 6.7e-10 38.7 1.7 0.12 12.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KPI40664.1 - 5.3e-09 35.8 4.3 0.022 14.6 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KPI40664.1 - 0.031 14.4 2.4 23 5.2 0.2 3.3 3 0 0 3 3 3 0 NusA-like KH domain MOEP19 PF16005.5 KPI40664.1 - 0.056 13.4 0.0 10 6.2 0.0 2.6 3 0 0 3 3 3 0 KH-like RNA-binding domain Abhydrolase_6 PF12697.7 KPI40665.1 - 1.7e-19 71.4 4.2 2.2e-19 71.0 4.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI40665.1 - 3.9e-07 29.6 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI40665.1 - 5e-07 29.6 0.2 2e-05 24.4 0.8 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1168 PF06658.12 KPI40666.1 - 1.2e-35 122.3 16.9 1.6e-35 121.9 16.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) SprA-related PF12118.8 KPI40666.1 - 0.025 13.7 6.6 0.03 13.5 6.6 1.1 1 0 0 1 1 1 0 SprA-related family PPL5 PF18168.1 KPI40666.1 - 0.17 11.2 3.4 0.2 10.9 3.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 eIF-3_zeta PF05091.12 KPI40666.1 - 0.37 9.7 7.8 0.42 9.5 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1682 PF07946.14 KPI40666.1 - 0.63 9.2 11.9 0.8 8.9 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rrn6 PF10214.9 KPI40666.1 - 0.68 8.4 6.6 0.72 8.3 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 KPI40666.1 - 7.1 5.3 9.2 8 5.1 9.2 1.1 1 0 0 1 1 1 0 Presenilin Ldh_1_N PF00056.23 KPI40667.1 - 1.7e-44 151.3 0.1 2.6e-44 150.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KPI40667.1 - 3.9e-42 144.0 0.1 4.5e-41 140.6 0.2 2.3 2 1 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KPI40667.1 - 0.0063 15.6 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KPI40667.1 - 0.039 14.4 0.6 0.14 12.6 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KPI40667.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.16 KPI40667.1 - 0.29 10.6 2.8 0.91 9.0 0.2 2.5 2 1 0 3 3 3 0 Family 4 glycosyl hydrolase Methyltransf_16 PF10294.9 KPI40668.1 - 3.4e-18 66.0 0.0 4.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Aldedh PF00171.22 KPI40669.1 - 5.1e-120 401.1 0.0 5.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KPI40670.1 - 1.7e-17 63.4 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KPI40671.1 - 8.7e-06 25.7 0.1 0.062 13.2 0.1 3.1 2 2 0 2 2 2 2 NAD(P)H-binding CH PF00307.31 KPI40672.1 - 8.2e-07 29.2 0.0 9.3e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.27 KPI40672.1 - 0.017 14.9 1.3 0.049 13.4 1.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PI3_PI4_kinase PF00454.27 KPI40673.1 - 5.7e-42 144.3 0.0 8.5e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3328 PF11807.8 KPI40674.1 - 1.7e-51 175.1 0.1 2.1e-51 174.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Complex1_LYR PF05347.15 KPI40676.1 - 0.0026 17.8 0.7 0.0026 17.8 0.7 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) V-SNARE_C PF12352.8 KPI40677.1 - 5.2e-13 49.1 0.2 1e-12 48.1 0.2 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KPI40677.1 - 0.0055 16.6 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.16 KPI40677.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 SDH_alpha PF03313.15 KPI40677.1 - 0.14 11.8 0.7 0.25 11.0 0.7 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain Acyl-CoA_dh_2 PF08028.11 KPI40678.1 - 4.6e-16 59.3 0.4 7.2e-16 58.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI40678.1 - 9.6e-07 28.9 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI40678.1 - 1.2e-06 29.1 0.0 3.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KPI40678.1 - 0.002 18.4 0.1 0.0034 17.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COQ7 PF03232.13 KPI40679.1 - 0.0047 16.7 2.1 0.0095 15.7 2.1 1.4 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF726 PF05277.12 KPI40680.1 - 3.8e-103 345.0 1.2 7.1e-99 331.0 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF726) Thioesterase PF00975.20 KPI40680.1 - 0.01 16.0 0.4 0.029 14.5 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain DUF4179 PF13786.6 KPI40680.1 - 0.045 14.2 0.2 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) WD40 PF00400.32 KPI40681.1 - 7.2e-51 169.1 19.7 1.5e-08 35.1 1.4 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI40681.1 - 1.4e-13 51.0 0.0 0.0016 18.7 0.1 5.6 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI40681.1 - 4.2e-06 25.7 0.1 0.0026 16.5 0.0 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPI40681.1 - 0.00066 18.5 0.0 0.58 8.8 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 KPI40681.1 - 0.012 14.6 0.0 0.13 11.2 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein bZIP_2 PF07716.15 KPI40681.1 - 0.17 12.0 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper AMP-binding PF00501.28 KPI40683.1 - 3.5e-40 137.9 0.0 4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI40683.1 - 2.9e-12 47.4 0.0 6.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Albumin_I_a PF16720.5 KPI40683.1 - 0.007 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Albumin I chain a KxDL PF10241.9 KPI40684.1 - 0.009 16.3 0.3 2.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein LisH PF08513.11 KPI40685.1 - 8.6e-08 31.9 0.1 1.6e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.32 KPI40685.1 - 4.9e-07 30.3 9.6 1.9 9.5 0.0 6.9 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI40685.1 - 1.6e-06 28.3 0.1 0.0021 18.3 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI40685.1 - 0.071 13.0 0.1 0.89 9.4 0.0 2.6 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A adh_short_C2 PF13561.6 KPI40686.1 - 2.8e-17 63.1 0.4 4.1e-17 62.5 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40686.1 - 1.9e-15 56.8 0.5 2.4e-15 56.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40686.1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 KR domain COPIIcoated_ERV PF07970.12 KPI40687.1 - 1.1e-34 120.3 0.0 2.5e-34 119.1 0.0 1.6 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KPI40687.1 - 3.1e-23 81.9 0.1 5.1e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Dyp_perox PF04261.12 KPI40688.1 - 9.3e-87 291.1 0.0 1.1e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family EIF_2_alpha PF07541.12 KPI40689.1 - 5.9e-35 119.9 0.0 1.1e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KPI40689.1 - 1.1e-13 51.3 0.6 2.2e-13 50.3 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Alpha-amylase PF00128.24 KPI40690.1 - 1.9e-22 80.3 0.0 9.3e-21 74.7 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KPI40690.1 - 6e-07 29.5 0.0 2.8e-06 27.4 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) p450 PF00067.22 KPI40691.1 - 9e-54 182.9 0.0 1.2e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_1 PF00515.28 KPI40692.1 - 6.7e-08 32.0 0.1 0.13 12.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI40692.1 - 5.9e-07 29.1 8.5 0.064 13.4 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KPI40692.1 - 3.2e-05 24.0 3.6 0.0009 19.3 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPI40692.1 - 0.00021 21.9 14.8 0.005 17.5 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI40692.1 - 0.00047 20.2 0.4 0.065 13.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPI40692.1 - 0.002 18.3 1.0 0.35 11.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPI40692.1 - 0.022 14.5 0.9 0.73 9.6 0.0 3.3 3 1 1 4 4 4 0 TPR repeat RPN7 PF10602.9 KPI40692.1 - 0.024 14.4 0.2 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 KPI40692.1 - 0.11 12.6 4.4 29 5.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI40692.1 - 0.49 10.7 13.0 4.7 7.6 0.0 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KPI40692.1 - 0.71 10.4 11.2 2.7 8.6 0.0 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.7 KPI40693.1 - 1.6e-29 102.3 0.9 9.4e-14 51.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI40693.1 - 1.4e-24 86.1 0.8 3.4e-09 37.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KPI40693.1 - 4.4e-22 77.5 6.5 1.6e-07 31.5 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KPI40693.1 - 5.4e-19 66.3 0.6 6.7e-05 23.0 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KPI40693.1 - 1.2e-18 66.9 0.5 3.6e-07 30.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DAOA PF15199.6 KPI40693.1 - 0.021 15.2 0.3 0.039 14.4 0.3 1.4 1 0 0 1 1 1 0 D-amino acid oxidase activator bZIP_1 PF00170.21 KPI40693.1 - 3 8.0 5.5 4.9 7.3 5.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor SnoaL_4 PF13577.6 KPI40694.1 - 2.3e-18 66.6 0.0 2.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain tRNA-synt_2d PF01409.20 KPI40695.1 - 2.3e-50 171.4 0.5 6.1e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KPI40695.1 - 4.3e-27 94.4 0.0 1.4e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF2034 PF10356.9 KPI40696.1 - 4e-17 62.2 0.0 2.3e-12 46.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KPI40696.1 - 5.6e-05 23.1 0.0 0.00046 20.2 0.0 2.1 2 0 0 2 2 2 1 Restriction endonuclease FAD_binding_3 PF01494.19 KPI40697.1 - 5.7e-91 305.4 0.9 7e-91 305.1 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPI40697.1 - 1.4e-05 24.4 0.9 0.0021 17.2 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI40697.1 - 2.6e-05 23.6 0.3 0.0031 16.8 0.2 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40697.1 - 3.1e-05 23.7 0.1 0.14 11.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Mqo PF06039.15 KPI40697.1 - 0.00071 18.2 0.2 0.15 10.6 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KPI40697.1 - 0.005 17.0 0.2 0.021 15.1 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI40697.1 - 0.013 14.7 0.1 0.032 13.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KPI40697.1 - 0.027 13.6 0.2 0.071 12.2 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KPI40697.1 - 0.036 13.1 0.4 0.11 11.5 0.4 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KPI40697.1 - 0.064 12.0 0.4 3.8 6.1 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 KPI40697.1 - 0.082 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.24 KPI40697.1 - 0.096 12.0 0.0 9.7 5.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPI40697.1 - 0.12 13.0 0.2 2.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_18 PF00704.28 KPI40698.1 - 9.9e-52 176.6 0.6 9.9e-52 176.6 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.18 KPI40699.1 - 3.3e-17 62.4 0.3 4.7e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Inhibitor_Mig-6 PF11555.8 KPI40699.1 - 0.24 11.5 1.6 0.57 10.3 0.9 2.0 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Abhydrolase_6 PF12697.7 KPI40700.1 - 5.9e-09 36.9 1.5 7.5e-09 36.5 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI40700.1 - 6.5e-09 35.4 0.0 1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KPI40700.1 - 2e-08 33.3 0.0 1.3e-07 30.7 0.0 1.9 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KPI40700.1 - 1.8e-07 31.1 0.0 2.6e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 KPI40700.1 - 4.5e-07 29.0 0.0 6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KPI40700.1 - 2e-06 27.4 0.1 4e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KPI40700.1 - 3e-05 24.1 0.0 4.9e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KPI40700.1 - 8.5e-05 22.2 0.0 0.00052 19.6 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Asp PF00026.23 KPI40701.1 - 5.2e-08 32.7 0.0 0.00012 21.6 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic aspartyl protease Sde2_N_Ubi PF13019.6 KPI40703.1 - 9.5e-47 158.9 1.8 2.5e-46 157.5 1.8 1.8 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain CFEM PF05730.11 KPI40704.1 - 2.3e-11 43.6 18.5 4.1e-11 42.8 18.5 1.4 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 KPI40704.1 - 0.12 12.4 2.3 0.15 12.2 0.5 2.0 2 0 0 2 2 2 0 Podoplanin PLDc PF00614.22 KPI40705.1 - 2.7e-16 59.0 1.2 2.1e-08 34.0 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KPI40705.1 - 2.7e-16 59.7 0.2 1.3e-06 28.3 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain Sec63 PF02889.16 KPI40706.1 - 1.1e-34 119.8 0.0 1.6e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KPI40706.1 - 1.1e-27 97.0 0.1 3.5e-27 95.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI40706.1 - 4.1e-13 49.7 0.0 9.4e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI40706.1 - 2.1e-08 34.5 0.0 3.5e-07 30.5 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KPI40706.1 - 0.0002 21.1 0.0 0.00078 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI40706.1 - 0.00031 21.0 0.1 0.0014 18.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI40706.1 - 0.0058 17.0 0.1 0.035 14.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KPI40706.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain HHH_5 PF14520.6 KPI40706.1 - 0.012 16.2 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain T2SSE PF00437.20 KPI40706.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 KPI40706.1 - 0.023 14.6 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Helicase Cdd1 PF11731.8 KPI40706.1 - 0.061 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KPI40706.1 - 0.15 11.9 0.0 0.53 10.1 0.0 2.0 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda APH PF01636.23 KPI40707.1 - 1.2e-40 140.0 0.0 1.6e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KPI40707.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 KPI40707.1 - 0.012 14.8 0.0 1.1 8.4 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 KPI40707.1 - 0.044 13.1 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KPI40707.1 - 0.07 12.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.11 KPI40707.1 - 0.14 11.0 0.0 0.32 9.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) p450 PF00067.22 KPI40708.1 - 6.2e-42 143.9 0.0 7.8e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KPI40709.1 - 1.4e-07 30.7 3.6 2.3e-07 30.0 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Reprolysin_5 PF13688.6 KPI40710.1 - 2.4e-57 194.3 9.0 2.4e-57 194.3 9.0 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KPI40710.1 - 4.5e-51 173.5 3.4 8.3e-51 172.6 3.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KPI40710.1 - 5.5e-49 166.6 4.0 5.5e-49 166.6 4.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KPI40710.1 - 1.4e-16 61.1 29.6 1.4e-16 61.1 29.6 4.2 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KPI40710.1 - 3.9e-10 40.3 0.1 1.4e-09 38.5 0.1 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Amidohydro_3 PF07969.11 KPI40710.1 - 6.1e-09 35.9 0.3 1e-07 31.8 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPI40710.1 - 5.3e-06 26.0 0.0 1.5e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family ADAM_CR_2 PF17771.1 KPI40710.1 - 7.2e-05 23.2 13.4 7.2e-05 23.2 13.4 4.4 1 1 3 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KPI40710.1 - 0.0024 18.1 0.1 0.0053 17.0 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 KPI40710.1 - 0.0079 15.2 0.0 0.02 13.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M66 Transp_cyt_pur PF02133.15 KPI40711.1 - 3.1e-74 250.3 37.4 8.3e-74 248.9 37.4 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SyrA PF11089.8 KPI40711.1 - 0.071 13.2 1.1 0.23 11.6 1.1 1.8 1 0 0 1 1 1 0 Exopolysaccharide production repressor Palm_thioest PF02089.15 KPI40712.1 - 1.1e-78 264.4 0.0 1.4e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KPI40712.1 - 0.0004 19.8 0.0 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 KPI40712.1 - 0.0025 17.4 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) F-box PF00646.33 KPI40714.1 - 2e-05 24.4 0.1 0.00077 19.3 0.0 2.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KPI40714.1 - 0.0052 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box LRR_4 PF12799.7 KPI40714.1 - 1.4 9.5 9.0 4.7 7.8 0.4 3.9 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) SRA1 PF07304.11 KPI40716.1 - 1.2e-09 38.1 0.0 1.2e-09 38.1 0.0 3.1 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KPI40716.1 - 7.8e-05 22.5 1.5 0.0006 19.6 1.5 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KPI40716.1 - 0.0004 21.1 3.1 0.84 10.6 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Sec16 PF12932.7 KPI40716.1 - 0.0047 17.5 0.0 0.076 13.6 0.0 2.6 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region ANAPC4_WD40 PF12894.7 KPI40716.1 - 0.04 14.2 0.0 0.93 9.8 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 KPI40716.1 - 0.059 13.4 0.4 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Prp18 domain DUF4455 PF14643.6 KPI40716.1 - 0.078 11.6 0.4 0.13 10.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) MFS_1 PF07690.16 KPI40717.1 - 5.9e-19 68.2 47.3 1.1e-14 54.2 35.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI40717.1 - 3.6e-08 32.3 18.9 4.7e-08 31.9 18.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IMS PF00817.20 KPI40718.1 - 3.2e-36 124.6 0.0 6.9e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KPI40718.1 - 1.5e-18 67.6 0.2 6.8e-17 62.3 0.2 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KPI40718.1 - 0.0011 19.1 0.0 0.029 14.7 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif zf_UBZ PF18439.1 KPI40718.1 - 0.0062 16.1 1.0 0.018 14.6 1.0 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger HHH PF00633.23 KPI40718.1 - 0.13 12.2 0.1 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KPI40718.1 - 0.16 12.6 0.1 0.77 10.4 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain adh_short_C2 PF13561.6 KPI40719.1 - 1.2e-54 185.4 1.9 1.8e-54 184.7 1.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40719.1 - 2.2e-46 157.8 3.7 2.8e-46 157.4 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40719.1 - 1.1e-12 48.3 0.5 1.5e-12 47.8 0.5 1.1 1 0 0 1 1 1 1 KR domain DFP PF04127.15 KPI40719.1 - 0.019 14.8 1.5 0.052 13.4 1.5 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1372 PF07116.11 KPI40719.1 - 0.026 14.7 0.4 0.05 13.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) PEARLI-4 PF05278.12 KPI40719.1 - 0.13 11.8 0.3 0.18 11.3 0.3 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) 3HCDH_N PF02737.18 KPI40719.1 - 0.14 12.1 1.6 0.31 10.9 1.6 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KPI40720.1 - 1e-37 129.9 31.2 4.1e-37 127.9 23.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4564 PF15169.6 KPI40720.1 - 0.0078 16.0 0.3 0.022 14.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) AMP-binding PF00501.28 KPI40721.1 - 2.7e-87 293.1 0.0 4.3e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI40721.1 - 0.0023 18.8 0.2 0.0088 17.0 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pox_MCEL PF03291.16 KPI40721.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Sugar_tr PF00083.24 KPI40722.1 - 2.3e-88 297.0 26.8 2.9e-88 296.7 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40722.1 - 2.2e-26 92.7 42.4 6e-17 61.6 19.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 KPI40722.1 - 3.7e-05 22.6 3.8 0.021 13.6 0.1 2.2 2 0 0 2 2 2 2 Reduced folate carrier DUF1129 PF06570.11 KPI40722.1 - 3.3 7.1 5.2 10 5.5 5.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1751 PF08551.10 KPI40723.1 - 3.8e-25 88.3 1.3 9.4e-25 87.1 1.3 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KPI40723.1 - 2.7e-05 24.2 4.1 4.9e-05 23.4 4.1 1.4 1 0 0 1 1 1 1 Rhomboid family RNase_PH PF01138.21 KPI40724.1 - 9.4e-14 52.0 0.0 1.6e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GFA PF04828.14 KPI40725.1 - 6.5e-16 58.5 3.9 9.7e-11 41.9 0.2 3.4 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KPI40725.1 - 0.15 12.3 10.5 0.82 9.9 0.2 3.7 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 KPI40725.1 - 0.61 9.9 7.5 3.1 7.6 0.1 3.5 3 1 0 3 3 3 0 zinc-ribbon domain Ima1_N PF09779.9 KPI40725.1 - 1.8 9.4 10.4 2.6 8.9 0.4 2.9 3 0 0 3 3 3 0 Ima1 N-terminal domain Aha1_N PF09229.11 KPI40726.1 - 2.1e-36 125.1 0.2 6.5e-36 123.6 0.1 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KPI40726.1 - 1.7e-17 63.8 0.6 2.9e-17 63.1 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KPI40726.1 - 0.008 16.5 5.0 0.032 14.5 3.3 2.3 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Glyco_hydro_68 PF02435.16 KPI40726.1 - 0.04 12.8 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Levansucrase/Invertase Glyco_tranf_2_3 PF13641.6 KPI40727.1 - 1.9e-15 57.4 0.0 4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI40727.1 - 5e-14 52.5 0.0 8.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KPI40727.1 - 7.2e-14 52.2 0.0 7.2e-14 52.2 0.0 3.3 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KPI40727.1 - 2.1e-12 46.9 0.0 5.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF872 PF05915.12 KPI40727.1 - 0.11 12.7 1.2 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Cellulose_synt PF03552.14 KPI40727.1 - 1.1 7.7 7.7 8.6 4.7 0.0 3.5 2 1 2 4 4 4 0 Cellulose synthase Pribosyltran_N PF13793.6 KPI40728.1 - 2.9e-40 136.8 0.0 6.8e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KPI40728.1 - 4.8e-35 121.2 1.2 1.2e-27 97.1 0.7 2.9 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KPI40728.1 - 4e-14 52.4 0.2 7.1e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KPI40728.1 - 0.012 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RE_BsaWI PF18643.1 KPI40728.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 BsaWI restriction endonuclease type 2 SNAP PF14938.6 KPI40729.1 - 5.2e-113 377.2 9.5 5.9e-113 377.0 9.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KPI40729.1 - 5.8e-06 26.5 13.6 0.015 15.6 2.2 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KPI40729.1 - 6.3e-06 25.9 6.1 0.24 11.5 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI40729.1 - 0.04 14.1 8.0 9.7 6.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI40729.1 - 0.12 13.1 14.2 8 7.3 0.2 5.3 5 2 3 8 8 8 0 Tetratricopeptide repeat NSF PF02071.20 KPI40729.1 - 1.8 9.7 14.8 1.1 10.3 0.5 5.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_10 PF13374.6 KPI40729.1 - 3.7 7.5 5.4 4.6 7.3 0.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Catalase PF00199.19 KPI40730.1 - 9e-190 630.7 0.2 1.1e-189 630.4 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KPI40730.1 - 1.8e-09 37.7 0.1 7.4e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 Catalase-related immune-responsive Clr5 PF14420.6 KPI40731.1 - 9.4e-18 64.2 1.2 2.8e-17 62.7 1.2 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KPI40731.1 - 6e-06 26.5 6.4 2.9e-05 24.2 2.9 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPI40731.1 - 0.00032 21.2 2.8 0.084 13.7 0.1 3.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KPI40731.1 - 0.00047 20.0 0.1 0.002 18.1 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPI40731.1 - 0.001 19.1 0.0 0.0048 17.0 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPI40731.1 - 0.0095 15.9 0.0 0.077 13.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPI40731.1 - 0.011 15.5 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPI40731.1 - 0.012 16.2 3.5 0.094 13.4 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KPI40731.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_21 PF09976.9 KPI40731.1 - 0.036 13.8 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 KPI40731.1 - 0.1 12.3 0.9 0.43 10.3 0.1 2.3 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KPI40731.1 - 0.51 10.3 5.4 0.95 9.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI40731.1 - 1.1 10.1 8.8 3.4 8.6 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.22 KPI40732.1 - 3.3e-38 131.6 0.0 4.1e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_2_C PF02836.17 KPI40733.1 - 8.3e-13 48.1 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KPI40733.1 - 4.1e-12 46.3 0.2 1.2e-11 44.8 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KPI40733.1 - 2.1e-07 31.6 0.0 1.3e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 MmgE_PrpD PF03972.14 KPI40734.1 - 2.3e-104 349.4 0.8 2.8e-104 349.1 0.8 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Imm49 PF15575.6 KPI40734.1 - 0.26 11.0 1.1 0.66 9.7 1.0 1.7 2 0 0 2 2 2 0 Immunity protein 49 Cnl2_NKP2 PF09447.10 KPI40735.1 - 1.2e-07 31.8 0.3 2.4e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein TMF_TATA_bd PF12325.8 KPI40735.1 - 0.025 14.8 0.1 0.025 14.8 0.1 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RRN3 PF05327.11 KPI40735.1 - 0.11 11.0 4.6 0.14 10.6 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KPI40735.1 - 0.3 10.4 17.2 0.42 9.9 17.2 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 KPI40735.1 - 4.8 5.8 6.8 5.7 5.6 6.8 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KPI40735.1 - 7.6 5.2 7.3 11 4.7 7.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SWIRM-assoc_2 PF16496.5 KPI40735.1 - 9.9 4.9 11.9 14 4.4 11.9 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ctf8 PF09696.10 KPI40736.1 - 7.7e-38 130.0 0.0 9.5e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Ctf8 DUF1751 PF08551.10 KPI40737.1 - 0.0082 16.7 0.7 0.0082 16.7 0.7 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Snf7 PF03357.21 KPI40738.1 - 6.5e-47 159.3 16.7 7.9e-47 159.1 16.7 1.0 1 0 0 1 1 1 1 Snf7 Zwint PF15556.6 KPI40738.1 - 0.0011 18.5 6.8 0.0015 18.1 6.8 1.3 1 0 0 1 1 1 1 ZW10 interactor CLZ PF16526.5 KPI40738.1 - 0.003 17.9 7.8 0.021 15.1 0.1 3.3 2 1 2 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KPI40738.1 - 0.037 14.1 8.9 1.2 9.2 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) HHH_2 PF12826.7 KPI40738.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF848 PF05852.11 KPI40738.1 - 0.089 12.9 6.7 0.053 13.6 4.6 1.7 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.12 KPI40738.1 - 0.15 12.6 6.5 1.8 9.1 1.6 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SNARE PF05739.19 KPI40738.1 - 0.18 11.8 1.4 11 6.1 0.1 2.5 2 0 0 2 2 2 0 SNARE domain FlaC_arch PF05377.11 KPI40738.1 - 0.32 11.4 6.3 19 5.7 0.0 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.10 KPI40738.1 - 0.42 10.4 4.3 30 4.5 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 XhlA PF10779.9 KPI40738.1 - 3.6 7.9 10.8 4.2 7.7 0.1 3.7 2 1 2 4 4 4 0 Haemolysin XhlA MFS_1 PF07690.16 KPI40739.1 - 1.9e-17 63.3 33.5 1.9e-17 63.3 33.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 KPI40740.1 - 2.2e-34 118.7 2.3 2.3e-34 118.6 0.5 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40740.1 - 6.6e-25 88.0 0.3 6.6e-25 88.0 0.3 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40740.1 - 2e-06 27.8 0.6 3.7e-06 27.0 0.6 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI40740.1 - 0.023 14.6 0.7 0.048 13.6 0.7 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KPI40740.1 - 0.039 13.4 0.3 0.18 11.3 1.1 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPI40740.1 - 0.12 11.9 0.8 0.2 11.1 0.8 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 KPI40740.1 - 0.67 9.9 3.4 1.4 8.9 0.8 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PKD_channel PF08016.12 KPI40741.1 - 4.3e-06 25.7 5.9 0.0006 18.6 1.5 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 KPI40741.1 - 0.0049 16.1 13.6 0.094 11.9 3.1 2.2 1 1 1 2 2 2 2 Ion transport protein FAM76 PF16046.5 KPI40741.1 - 0.39 10.0 1.2 0.57 9.5 1.2 1.1 1 0 0 1 1 1 0 FAM76 protein Alpha-amylase PF00128.24 KPI40742.1 - 7.1e-19 68.6 1.8 1.3e-16 61.2 0.8 2.6 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.6 KPI40742.1 - 5.1e-07 30.2 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KPI40742.1 - 2e-06 27.5 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 VCBS PF13517.6 KPI40742.1 - 0.15 12.7 3.5 0.18 12.4 0.9 2.6 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Fungal_trans PF04082.18 KPI40745.1 - 6.1e-16 58.2 0.7 9.6e-16 57.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ENTH PF01417.20 KPI40746.1 - 7.3e-47 158.5 0.0 1.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KPI40746.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 KPI40746.1 - 0.002 17.9 7.2 0.11 12.5 0.6 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF1720 PF08226.11 KPI40746.1 - 0.0032 17.8 44.1 0.0032 17.8 44.1 5.6 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) DUF4264 PF14084.6 KPI40746.1 - 0.079 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) HflK_N PF12221.8 KPI40746.1 - 0.22 11.6 2.5 31 4.7 0.0 3.5 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Mito_carr PF00153.27 KPI40747.1 - 5.2e-55 183.4 0.1 3.1e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1180 PF06679.12 KPI40748.1 - 0.12 12.7 3.2 0.23 11.9 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DnaJ PF00226.31 KPI40749.1 - 9.1e-18 64.1 0.1 2.5e-17 62.8 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain LIM_bind PF01803.16 KPI40750.1 - 3.5e-38 131.5 1.2 3.5e-38 131.5 1.2 2.3 3 0 0 3 3 3 1 LIM-domain binding protein TP53IP5 PF15331.6 KPI40751.1 - 0.11 12.6 0.8 0.14 12.3 0.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 BTB PF00651.31 KPI40752.1 - 0.00032 20.9 0.1 0.0004 20.6 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain Caskin-Pro-rich PF16907.5 KPI40752.1 - 3.7 8.1 10.8 13 6.4 3.5 2.2 1 1 1 2 2 2 0 Proline rich region of Caskin proteins Sugar_tr PF00083.24 KPI40753.1 - 1.4e-93 314.3 28.2 1.8e-93 313.9 28.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40753.1 - 8.6e-24 84.1 38.8 5.7e-22 78.1 26.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KPI40754.1 - 0.041 13.3 0.0 0.73 9.3 0.0 2.7 2 2 0 2 2 2 0 short chain dehydrogenase PHO4 PF01384.20 KPI40754.1 - 0.072 12.1 1.6 0.11 11.5 1.6 1.2 1 0 0 1 1 1 0 Phosphate transporter family SnoaL_4 PF13577.6 KPI40755.1 - 1.1e-14 54.6 0.3 1.7e-14 54.1 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KPI40755.1 - 0.0014 19.2 0.2 0.0022 18.6 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF779 PF05610.11 KPI40755.1 - 0.088 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF779) COX6B PF02297.17 KPI40756.1 - 1.4e-18 66.9 6.4 1.7e-18 66.6 6.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 KPI40756.1 - 0.0091 15.9 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CX9C PF16860.5 KPI40756.1 - 0.022 14.8 1.9 0.035 14.1 1.9 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ion_trans_2 PF07885.16 KPI40757.1 - 1.4e-26 92.2 26.3 8.2e-16 57.7 5.5 3.4 3 0 0 3 3 3 2 Ion channel CENP-L PF13092.6 KPI40758.1 - 2.2e-24 86.5 0.3 3.2e-24 86.0 0.3 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Beta-lactamase PF00144.24 KPI40759.1 - 2.2e-43 148.8 0.5 4e-43 147.9 0.5 1.4 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KPI40759.1 - 0.028 14.0 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase enzyme family MoaF PF10703.9 KPI40759.1 - 0.11 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 MoaF N-terminal domain Aminotran_1_2 PF00155.21 KPI40760.1 - 5.9e-50 170.5 0.0 1.3e-46 159.5 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPI40760.1 - 0.00025 19.7 0.0 0.00036 19.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KPI40760.1 - 0.0005 19.1 0.0 0.00075 18.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPI40760.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase BCS1_N PF08740.11 KPI40761.1 - 3.6e-18 66.2 0.8 8.7e-18 65.0 0.8 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPI40761.1 - 5.2e-16 59.3 0.0 7.9e-08 32.8 0.0 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI40761.1 - 0.0037 17.7 0.1 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KPI40761.1 - 0.007 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPI40761.1 - 0.053 13.5 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KPI40761.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KPI40761.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPI40761.1 - 0.16 12.6 0.4 2.5 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF899 PF05988.12 KPI40762.1 - 4.2e-48 163.7 0.0 5.1e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Thioredoxin_14 PF18402.1 KPI40763.1 - 0.00056 19.9 0.2 13 5.7 0.0 3.9 1 1 3 4 4 4 2 Thioredoxin-like domain FAM27 PF15832.5 KPI40763.1 - 0.0073 16.8 1.1 46 4.6 0.0 3.9 1 1 3 4 4 4 1 FAM27 D and E protein family TFIIE-A_C PF11521.8 KPI40763.1 - 0.049 13.9 0.9 30 5.0 0.0 3.7 1 1 3 4 4 4 0 C-terminal general transcription factor TFIIE alpha Gpr1_Fun34_YaaH PF01184.19 KPI40764.1 - 4.4e-41 140.8 18.8 5.5e-41 140.5 18.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FixS PF03597.15 KPI40764.1 - 2 8.2 5.0 5.3 6.8 0.4 2.9 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type SdpI PF13630.6 KPI40764.1 - 5.9 7.1 10.8 0.54 10.4 1.4 2.6 2 0 0 2 2 2 0 SdpI/YhfL protein family GCFC PF07842.12 KPI40765.1 - 1e-27 97.5 0.7 2.2e-27 96.4 0.7 1.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KPI40765.1 - 4.4e-15 55.3 0.6 8.1e-15 54.4 0.6 1.4 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KPI40765.1 - 0.0046 17.3 3.1 0.013 15.9 3.1 1.7 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KPI40765.1 - 0.03 14.4 0.4 0.093 12.8 0.4 1.8 1 0 0 1 1 1 0 G-patch domain SART-1 PF03343.13 KPI40766.1 - 1e-155 519.8 61.4 1.3e-155 519.5 61.4 1.0 1 0 0 1 1 1 1 SART-1 family TP_methylase PF00590.20 KPI40766.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.1 3 1 0 3 3 3 0 Tetrapyrrole (Corrin/Porphyrin) Methylases GET2 PF08690.10 KPI40768.1 - 5.5e-10 39.4 6.7 1.4e-09 38.0 4.8 2.4 1 1 1 2 2 2 1 GET complex subunit GET2 DUF919 PF06034.11 KPI40768.1 - 0.051 13.4 0.4 0.088 12.7 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Vma12 PF11712.8 KPI40768.1 - 0.2 11.7 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Acetyltransf_1 PF00583.25 KPI40769.1 - 5.4e-07 29.9 0.0 9.2e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI40769.1 - 7.2e-06 26.3 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI40769.1 - 1e-05 25.5 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 KPI40770.1 - 1.2e-39 136.3 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.21 KPI40770.1 - 5.5e-06 26.4 0.0 0.00076 19.5 0.0 2.4 1 1 1 2 2 2 2 Endoribonuclease L-PSP PAD_N PF08526.10 KPI40770.1 - 0.091 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain RHH_1 PF01402.21 KPI40770.1 - 0.1 12.6 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF5115 PF17142.4 KPI40771.1 - 0.034 13.8 0.9 0.053 13.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) IMP_cyclohyd PF07826.11 KPI40771.1 - 0.055 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Acetyltransf_1 PF00583.25 KPI40772.1 - 2.6e-08 34.1 0.0 4.9e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI40772.1 - 0.001 19.5 0.0 0.0033 17.8 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI40772.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI40772.1 - 0.078 12.9 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein DUF4129 PF13559.6 KPI40772.1 - 0.13 12.5 2.2 2.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Amidase PF01425.21 KPI40773.1 - 9.2e-25 87.5 3.1 6.7e-24 84.6 2.3 2.1 2 0 0 2 2 2 2 Amidase Sugar_tr PF00083.24 KPI40774.1 - 1.7e-29 103.0 20.2 1.9e-29 102.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Epimerase PF01370.21 KPI40776.1 - 1.2e-20 74.1 0.0 1.7e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPI40776.1 - 2e-09 37.0 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KPI40776.1 - 8e-09 35.3 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI40776.1 - 2.2e-06 26.9 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPI40776.1 - 1.6e-05 24.9 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KPI40776.1 - 0.0056 16.2 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40776.1 - 0.017 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 KR domain SPECT1 PF18680.1 KPI40776.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 FAD_binding_3 PF01494.19 KPI40778.1 - 4e-06 26.3 1.2 9e-06 25.2 1.2 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI40778.1 - 4.2e-06 26.9 0.2 8.8e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI40778.1 - 6.6e-06 25.6 0.1 0.00022 20.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI40778.1 - 5.3e-05 23.2 0.3 0.00056 19.9 0.3 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 KPI40778.1 - 0.0012 18.5 0.4 0.0022 17.7 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI40778.1 - 0.0036 17.8 0.1 0.011 16.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI40778.1 - 0.008 15.3 0.4 0.012 14.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KPI40778.1 - 0.0082 15.4 0.1 0.018 14.3 0.2 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI40778.1 - 0.0098 14.6 0.1 0.018 13.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KPI40778.1 - 0.041 12.9 0.2 0.06 12.4 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KPI40778.1 - 0.059 12.7 0.1 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KPI40778.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 KPI40778.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Utp12 PF04003.12 KPI40779.1 - 2.8e-21 75.8 0.0 4.8e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KPI40779.1 - 2.4e-05 24.6 0.1 0.24 11.7 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like_2 PF13013.6 KPI40780.1 - 0.0033 17.4 0.1 0.0062 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like domain DUF2407_C PF13373.6 KPI40781.1 - 1.3e-41 142.0 0.0 1.9e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KPI40781.1 - 4.7e-29 101.0 0.0 7.6e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KPI40781.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family tRNA-synt_1c PF00749.21 KPI40782.1 - 4.1e-104 347.8 0.0 5.7e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KPI40782.1 - 1.4e-31 109.7 0.8 3.3e-30 105.2 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class I (E and Q), anti-codon binding domain Phasin PF05597.11 KPI40783.1 - 0.025 14.6 0.1 4.5 7.3 0.4 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GrpE PF01025.19 KPI40784.1 - 3.5e-38 130.9 6.5 5.3e-37 127.0 6.5 2.0 1 1 0 1 1 1 1 GrpE PMC2NT PF08066.12 KPI40784.1 - 0.26 12.0 2.1 0.4 11.4 0.7 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain HHH PF00633.23 KPI40785.1 - 0.0025 17.6 0.0 0.0084 15.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KPI40785.1 - 0.023 15.3 0.0 0.066 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain ATP-synt_ab PF00006.25 KPI40786.1 - 7e-67 225.2 0.0 9.4e-67 224.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KPI40786.1 - 1.5e-13 51.1 0.7 2.6e-13 50.3 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Sugar_tr PF00083.24 KPI40787.1 - 4.7e-17 62.0 5.8 5.1e-17 61.9 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40787.1 - 0.0082 15.1 1.3 0.0097 14.9 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5391 PF17369.2 KPI40787.1 - 2.9 7.9 8.8 7.8 6.5 8.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5391) DUF1476 PF07345.11 KPI40788.1 - 0.025 14.9 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta TRI12 PF06609.13 KPI40790.1 - 4.4e-42 144.3 27.3 5.6e-42 144.0 27.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI40790.1 - 4.9e-12 45.4 16.5 4.9e-12 45.4 16.5 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40790.1 - 4.2e-09 35.8 14.2 4.2e-09 35.8 14.2 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter HRDC PF00570.23 KPI40790.1 - 0.099 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 HRDC domain FAD_binding_3 PF01494.19 KPI40791.1 - 1.6e-12 47.4 0.3 1.8e-11 43.9 0.3 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KPI40791.1 - 0.22 10.6 0.0 0.34 9.9 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase HECT PF00632.25 KPI40792.1 - 2.4e-91 306.4 0.0 4.8e-91 305.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 KPI40792.1 - 1.3e-73 248.1 0.0 1.3e-73 248.1 0.0 5.1 6 0 0 6 6 6 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KPI40792.1 - 3.1e-48 165.0 0.1 1.1e-47 163.2 0.1 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KPI40792.1 - 8.5e-17 60.0 18.9 1.1e-07 31.0 1.7 3.9 3 0 0 3 3 3 3 Ubiquitin binding region DUF3237 PF11578.8 KPI40793.1 - 1.3e-18 67.3 0.0 1.5e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-C2H2 PF00096.26 KPI40794.1 - 6.9e-05 23.1 13.1 0.094 13.2 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type RasGAP_C PF03836.15 KPI40794.1 - 0.0022 18.1 0.2 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 RasGAP C-terminus zf-C2H2_aberr PF17017.5 KPI40794.1 - 0.0033 17.6 0.3 0.0033 17.6 0.3 1.8 2 0 0 2 2 2 1 Aberrant zinc-finger Snapin_Pallidin PF14712.6 KPI40794.1 - 0.09 13.2 1.9 0.1 13.0 0.9 1.6 2 0 0 2 2 2 0 Snapin/Pallidin zf-C2H2_4 PF13894.6 KPI40794.1 - 0.16 12.9 13.2 0.96 10.5 0.5 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger GAS PF13851.6 KPI40794.1 - 0.31 10.4 0.1 0.31 10.4 0.1 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 KPI40794.1 - 0.33 11.1 6.9 0.64 10.1 6.9 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation OmpA PF00691.20 KPI40795.1 - 0.031 14.7 1.0 0.091 13.1 1.0 1.8 1 0 0 1 1 1 0 OmpA family Macoilin PF09726.9 KPI40795.1 - 2.3 6.7 3.4 2.8 6.4 3.4 1.1 1 0 0 1 1 1 0 Macoilin family FMO-like PF00743.19 KPI40796.1 - 8.4e-18 64.1 2.0 4.6e-15 55.0 0.1 3.2 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI40796.1 - 2.1e-11 43.8 0.0 6.6e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI40796.1 - 4.1e-09 36.0 0.0 6.6e-06 25.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI40796.1 - 1.3e-07 31.2 0.0 1.3e-05 24.6 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI40796.1 - 3.1e-07 29.9 0.0 7.4e-06 25.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI40796.1 - 0.00044 20.3 0.1 0.51 10.3 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KPI40796.1 - 0.0086 15.7 0.0 0.64 9.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI40796.1 - 0.017 14.4 0.0 0.33 10.2 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 KPI40796.1 - 0.15 12.7 0.7 3.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 KPI40796.1 - 0.22 10.8 0.0 9.8 5.4 0.0 2.4 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain NAD_binding_1 PF00175.21 KPI40797.1 - 8.1e-15 55.4 0.0 1.5e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KPI40797.1 - 1.5e-07 32.0 0.0 4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KPI40797.1 - 9e-07 29.2 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KPI40797.1 - 1.7e-05 25.0 0.0 6.5e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KPI40797.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Protoglobin Molydop_binding PF01568.21 KPI40797.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Ceramidase PF05875.12 KPI40798.1 - 8.5e-100 333.5 2.4 9.7e-100 333.3 2.4 1.0 1 0 0 1 1 1 1 Ceramidase 6PF2K PF01591.18 KPI40799.1 - 5.4e-62 209.0 1.7 1.8e-56 190.9 0.0 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KPI40799.1 - 2.4e-38 131.8 0.0 3.8e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KPI40799.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ThylakoidFormat PF11264.8 KPI40799.1 - 0.0088 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Thylakoid formation protein AAA_33 PF13671.6 KPI40799.1 - 0.021 15.0 0.1 0.055 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATG_C PF09333.11 KPI40800.1 - 5.6 7.4 7.0 3 8.3 1.9 2.3 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain Hydrolase_like PF13242.6 KPI40801.1 - 0.0072 16.4 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KPI40801.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1048 PF06304.11 KPI40801.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Peptidase_S10 PF00450.22 KPI40802.1 - 4.3e-83 280.1 0.0 5.3e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PCNA_C PF02747.15 KPI40803.1 - 1.2e-49 167.7 0.0 2.3e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KPI40803.1 - 2.2e-33 114.7 2.3 7.5e-32 109.7 2.3 2.3 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KPI40803.1 - 1.2e-05 24.9 0.0 0.02 14.3 0.0 2.1 1 1 1 2 2 2 2 Rad9 Rad1 PF02144.16 KPI40803.1 - 3.9e-05 22.9 0.4 0.033 13.2 0.0 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Sugar_tr PF00083.24 KPI40804.1 - 3.8e-63 213.9 24.0 4.6e-39 134.5 2.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI40804.1 - 1.6e-11 43.7 20.9 1.6e-11 43.7 20.9 3.1 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_1 PF07690.16 KPI40806.1 - 9.6e-40 136.6 24.3 9.6e-40 136.6 24.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40806.1 - 8.7e-08 31.5 9.2 7.6e-07 28.3 6.5 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPI40806.1 - 0.00025 19.6 0.9 0.00045 18.8 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KPI40806.1 - 0.011 14.3 0.1 0.023 13.3 0.0 1.6 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DBINO PF13892.6 KPI40807.1 - 0.12 12.8 16.1 0.16 12.3 16.1 1.2 1 0 0 1 1 1 0 DNA-binding domain DUF1682 PF07946.14 KPI40807.1 - 0.88 8.7 14.4 1.1 8.4 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.10 KPI40807.1 - 3.3 7.8 8.6 4.5 7.3 8.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PPL5 PF18168.1 KPI40807.1 - 5 6.3 6.9 3.4 6.9 5.7 1.3 1 1 0 1 1 1 0 Prim-pol family 5 NARP1 PF12569.8 KPI40807.1 - 5.7 5.7 9.9 6.7 5.5 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Acid_PPase PF12689.7 KPI40808.1 - 4.8e-47 159.9 0.0 4.8e-44 150.2 0.0 2.1 1 1 0 1 1 1 1 Acid Phosphatase SCAB-ABD PF16711.5 KPI40808.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein ATE_C PF04377.15 KPI40809.1 - 1.3e-44 152.1 1.0 2e-44 151.4 1.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus PepSY_2 PF13670.6 KPI40811.1 - 0.014 15.4 1.8 0.014 15.4 1.8 1.9 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain GRAB PF10375.9 KPI40811.1 - 0.9 9.5 19.7 82 3.3 0.1 6.0 6 0 0 6 6 6 0 GRIP-related Arf-binding domain OprF PF05736.11 KPI40811.1 - 8.6 6.1 7.6 50 3.6 0.5 3.2 2 1 2 4 4 4 0 OprF membrane domain Mt_ATP-synt_D PF05873.12 KPI40812.1 - 4.3e-18 65.6 0.5 5.5e-18 65.3 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TPR_MLP1_2 PF07926.12 KPI40812.1 - 0.0071 16.4 2.0 0.099 12.7 1.9 2.0 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein 120_Rick_ant PF12574.8 KPI40812.1 - 0.019 14.2 0.2 0.025 13.8 0.2 1.1 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen E3_UbLigase_R4 PF13764.6 KPI40812.1 - 0.1 10.7 0.1 0.12 10.5 0.1 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 GATA PF00320.27 KPI40813.1 - 2.2e-15 56.0 2.7 3.6e-15 55.3 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger CENP-F_leu_zip PF10473.9 KPI40813.1 - 0.0033 17.5 3.8 0.0053 16.8 3.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TF_Zn_Ribbon PF08271.12 KPI40813.1 - 0.0093 15.5 0.4 0.017 14.6 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Macoilin PF09726.9 KPI40813.1 - 0.011 14.3 0.9 0.013 14.1 0.9 1.1 1 0 0 1 1 1 0 Macoilin family Elf1 PF05129.13 KPI40813.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.12 KPI40813.1 - 0.12 12.6 0.9 0.19 11.9 0.9 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2353 PF09789.9 KPI40813.1 - 0.16 11.3 5.5 0.36 10.2 4.7 1.8 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Cep57_CLD_2 PF14197.6 KPI40813.1 - 0.22 11.6 8.2 0.43 10.7 8.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 KPI40813.1 - 3.2 8.3 11.5 0.25 11.8 1.8 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF3328 PF11807.8 KPI40814.1 - 1.3e-29 103.6 1.7 5.3e-29 101.6 1.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) OATP PF03137.20 KPI40814.1 - 0.25 9.6 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KPI40815.1 - 1.4e-40 139.5 0.0 8.8e-34 117.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Galactosyl_T PF01762.21 KPI40816.1 - 0.041 13.7 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Galactosyltransferase Carn_acyltransf PF00755.20 KPI40817.1 - 5.5e-201 669.2 0.2 6.3e-201 669.0 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AA_permease_2 PF13520.6 KPI40818.1 - 1.2e-54 185.8 54.0 1.4e-54 185.5 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI40818.1 - 7e-14 51.3 45.9 1.2e-13 50.6 45.9 1.3 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KPI40820.1 - 4.2e-46 157.7 2.8 4.6e-46 157.6 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40820.1 - 6.6e-14 51.6 9.4 7.3e-14 51.5 9.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CitMHS PF03600.16 KPI40820.1 - 8.6 5.5 11.4 0.75 8.9 6.2 1.7 1 1 1 2 2 2 0 Citrate transporter Methyltransf_25 PF13649.6 KPI40821.1 - 2.1e-11 44.4 0.0 4.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI40821.1 - 4.6e-11 42.5 0.0 7e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KPI40821.1 - 4.9e-10 39.9 0.0 8.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI40821.1 - 1.4e-07 32.1 0.0 3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40821.1 - 7.5e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI40821.1 - 0.0043 16.9 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Hydrolase PF00702.26 KPI40823.1 - 2.8e-18 67.0 0.9 2e-11 44.6 1.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPI40823.1 - 3.1e-16 59.4 0.0 6.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPI40823.1 - 0.0017 18.4 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPI40823.1 - 0.0023 17.7 0.3 0.017 14.9 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase G0-G1_switch_2 PF15103.6 KPI40823.1 - 0.098 13.1 1.5 0.43 11.0 0.0 2.6 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF4131 PF13567.6 KPI40823.1 - 0.19 11.4 0.4 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Nop16 PF09420.10 KPI40824.1 - 7.1e-63 212.4 10.9 8.1e-63 212.2 10.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 WD40 PF00400.32 KPI40825.1 - 3.5e-06 27.7 0.0 0.2 12.6 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI40825.1 - 0.0085 16.4 0.0 2 8.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BSD PF03909.17 KPI40826.1 - 9.2e-24 83.2 4.7 2.8e-12 46.5 0.1 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KPI40826.1 - 1.5e-20 73.3 0.1 6.2e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Imm5 PF14423.6 KPI40826.1 - 0.12 12.6 0.6 0.47 10.7 0.2 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 Headcase PF16002.5 KPI40826.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Headcase protein Cnd1 PF12717.7 KPI40828.1 - 2.8e-06 27.4 0.9 0.00088 19.3 0.0 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KPI40828.1 - 1.7e-05 24.5 0.1 0.00086 18.9 0.1 2.3 2 0 0 2 2 2 1 CLASP N terminal HALZ PF02183.18 KPI40828.1 - 0.00028 21.0 2.2 0.55 10.5 0.0 3.1 2 1 0 2 2 2 2 Homeobox associated leucine zipper HEAT PF02985.22 KPI40828.1 - 0.00041 20.4 1.7 6.3 7.3 0.1 5.2 6 0 0 6 6 4 1 HEAT repeat MAD PF05557.13 KPI40828.1 - 0.0014 17.1 3.6 0.0027 16.2 3.6 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 KPI40828.1 - 0.0026 17.8 7.1 0.011 15.8 7.1 2.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein TAN PF11640.8 KPI40828.1 - 0.01 16.0 2.2 0.014 15.6 0.2 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 KPI40828.1 - 0.01 14.4 1.0 0.084 11.4 1.0 2.1 1 1 0 1 1 1 0 Adaptin N terminal region bZIP_1 PF00170.21 KPI40828.1 - 0.026 14.6 8.0 1.8 8.7 1.6 2.9 2 0 0 2 2 2 0 bZIP transcription factor Syntaxin PF00804.25 KPI40828.1 - 0.029 14.1 2.8 0.095 12.4 2.8 1.8 1 0 0 1 1 1 0 Syntaxin TEX13 PF15186.6 KPI40828.1 - 0.059 13.1 7.2 1.1 8.9 3.3 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Mod_r PF07200.13 KPI40828.1 - 0.095 12.8 5.9 0.25 11.5 5.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Occludin_ELL PF07303.13 KPI40828.1 - 0.13 13.0 2.1 2.6 8.8 2.3 2.5 2 0 0 2 2 2 0 Occludin homology domain DUF1640 PF07798.11 KPI40828.1 - 0.17 11.9 9.2 0.58 10.2 8.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GAS PF13851.6 KPI40828.1 - 0.3 10.4 12.0 0.034 13.5 7.0 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KPI40828.1 - 0.35 10.7 11.3 1.3 8.8 3.7 3.0 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.8 KPI40828.1 - 0.44 10.6 8.2 1.1 9.3 8.2 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KPI40828.1 - 1.5 9.2 9.6 0.1 13.0 4.0 1.8 2 0 0 2 2 2 0 Fez1 Atg14 PF10186.9 KPI40828.1 - 3.7 6.6 6.5 6.9 5.6 6.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 KPI40828.1 - 5.8 6.3 13.6 0.16 11.4 6.4 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 NRBF2 PF08961.10 KPI40828.1 - 7.3 6.1 9.6 4.5 6.8 1.5 2.5 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Aa_trans PF01490.18 KPI40829.1 - 2.1e-50 171.7 17.7 1.8e-27 96.1 7.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein EF-hand_1 PF00036.32 KPI40830.1 - 1.1e-13 49.7 7.3 2e-05 23.8 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KPI40830.1 - 3.6e-13 49.7 2.3 7e-06 26.4 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KPI40830.1 - 5.6e-13 47.7 5.1 6.1e-05 22.6 0.3 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KPI40830.1 - 1.9e-10 40.4 7.3 0.00026 20.7 0.9 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KPI40830.1 - 9.8e-06 25.8 0.0 4.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KPI40830.1 - 0.0044 16.9 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KPI40830.1 - 0.0096 15.9 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Caleosin related protein EF-hand_5 PF13202.6 KPI40830.1 - 0.019 14.5 4.0 0.27 10.8 0.1 3.1 4 0 0 4 4 4 0 EF hand PsbU PF06514.11 KPI40830.1 - 0.028 14.4 0.1 0.14 12.2 0.0 2.0 2 1 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) HTH_39 PF14090.6 KPI40830.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain EFhand_Ca_insen PF08726.10 KPI40830.1 - 0.29 11.3 1.6 0.65 10.1 0.0 2.3 3 0 0 3 3 3 0 Ca2+ insensitive EF hand DUF4106 PF13388.6 KPI40830.1 - 0.46 9.7 8.3 0.63 9.2 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Methyltransf_10 PF05971.12 KPI40832.1 - 2e-35 122.6 2.7 2.5e-22 79.6 0.2 3.8 2 2 0 2 2 2 2 RNA methyltransferase MTS PF05175.14 KPI40832.1 - 0.0017 17.9 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 KPI40832.1 - 0.041 13.3 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Herpes_U47 PF05467.11 KPI40832.1 - 0.58 8.2 5.5 0.76 7.8 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Cytochrom_C PF00034.21 KPI40834.1 - 1.4e-10 42.2 0.0 1.9e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KPI40834.1 - 9.8e-08 32.2 0.8 5.6e-07 29.8 0.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KPI40834.1 - 0.00035 20.3 0.1 0.0021 17.8 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Complex1_51K PF01512.17 KPI40835.1 - 2.1e-45 154.3 0.0 3.7e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KPI40835.1 - 6e-29 99.9 0.3 1.2e-28 98.9 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KPI40835.1 - 2.2e-09 37.0 0.0 4.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 KPI40835.1 - 0.63 10.1 2.2 0.42 10.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Fungal_trans PF04082.18 KPI40836.1 - 2.8e-15 56.1 0.0 4.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI40836.1 - 4.9e-07 29.8 6.4 8.7e-07 29.0 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NepR PF18557.1 KPI40836.1 - 0.12 12.0 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Anti-sigma factor NepR zf-C2H2_4 PF13894.6 KPI40837.1 - 0.013 16.2 7.8 0.71 10.9 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI40837.1 - 0.034 14.6 0.3 0.034 14.6 0.3 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type GTP-bdg_M PF16360.5 KPI40838.1 - 1.5 9.5 4.5 0.53 10.9 0.2 2.1 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DnaJ PF00226.31 KPI40839.1 - 4.6e-17 61.9 2.0 1.1e-16 60.7 2.0 1.7 1 0 0 1 1 1 1 DnaJ domain Sec62 PF03839.16 KPI40839.1 - 0.063 12.8 3.2 0.16 11.5 3.2 1.8 1 1 0 1 1 1 0 Translocation protein Sec62 DUF1616 PF07760.11 KPI40839.1 - 0.17 11.2 4.3 0.34 10.2 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) SUR7 PF06687.12 KPI40839.1 - 1.1 8.9 6.5 1.5 8.4 6.5 1.2 1 0 0 1 1 1 0 SUR7/PalI family AA_permease_C PF13906.6 KPI40839.1 - 3.6 7.7 8.2 10 6.3 0.5 2.3 1 1 1 2 2 2 0 C-terminus of AA_permease DNA_pol_phi PF04931.13 KPI40840.1 - 0.29 9.2 7.5 0.37 8.8 7.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi ADH_zinc_N PF00107.26 KPI40841.1 - 2.9e-24 85.5 0.0 4.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI40841.1 - 3e-20 72.1 0.2 7e-20 70.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI40841.1 - 1.3e-10 41.1 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI40841.1 - 7.9e-06 27.0 0.0 1.5e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPI40841.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 KPI40841.1 - 0.037 14.7 0.1 0.12 13.1 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain Prenyltransf PF01255.19 KPI40842.1 - 2e-67 227.0 0.5 1.5e-38 132.5 0.0 2.0 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Fungal_trans PF04082.18 KPI40844.1 - 2.5e-09 36.5 0.3 1.1e-08 34.4 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4696 PF15767.5 KPI40844.1 - 0.036 12.7 0.2 0.051 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4696) rve_3 PF13683.6 KPI40844.1 - 0.14 11.9 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain SNF2_N PF00176.23 KPI40845.1 - 7e-49 166.4 0.2 1.2e-42 145.9 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI40845.1 - 6e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI40845.1 - 0.00085 19.4 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit RRM_1 PF00076.22 KPI40846.1 - 6.2e-16 58.0 0.0 8.4e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPI40846.1 - 0.00072 19.2 0.0 0.0025 17.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI40846.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KPI40846.1 - 0.05 13.7 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif MGC-24 PF05283.11 KPI40848.1 - 0.0019 18.7 0.2 0.0019 18.7 0.2 2.1 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 KPI40848.1 - 0.068 14.1 0.0 0.15 12.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fe-ADH PF00465.19 KPI40849.1 - 1.6e-30 106.2 0.1 1.9e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPI40849.1 - 0.00035 20.4 0.1 0.0096 15.6 0.1 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase adh_short_C2 PF13561.6 KPI40850.1 - 1.5e-36 126.1 0.7 1.4e-35 123.0 0.7 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40850.1 - 1.1e-33 116.3 0.2 1.9e-33 115.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40850.1 - 2e-10 40.9 0.2 4.4e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KPI40850.1 - 1.4e-05 25.4 0.0 2.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KPI40850.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PLA2_B PF01735.18 KPI40851.1 - 0.2 10.0 1.1 0.28 9.5 1.1 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Acyl-CoA_dh_2 PF08028.11 KPI40851.1 - 0.38 11.0 2.0 3.6 7.9 0.2 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 KPI40852.1 - 9.7e-53 179.1 5.8 1.2e-52 178.9 5.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI40852.1 - 1.3e-42 145.5 1.8 1.7e-42 145.1 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI40852.1 - 6.8e-07 29.4 3.1 2.3e-06 27.6 3.1 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPI40852.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPA_2 PF17809.1 KPI40852.1 - 0.074 12.9 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 UPA domain BMC PF00936.19 KPI40852.1 - 0.51 10.4 5.9 0.15 12.1 0.7 2.5 2 0 0 2 2 2 0 BMC domain DUF3636 PF12331.8 KPI40853.1 - 2.3e-48 163.8 1.0 4.8e-48 162.7 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) SPATA24 PF15175.6 KPI40853.1 - 0.0046 16.9 7.4 0.0082 16.1 7.4 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Golgin_A5 PF09787.9 KPI40853.1 - 0.0065 16.0 12.1 0.011 15.2 12.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Yuri_gagarin PF15934.5 KPI40853.1 - 0.042 13.7 4.3 0.072 12.9 4.3 1.3 1 0 0 1 1 1 0 Yuri gagarin FapA PF03961.13 KPI40853.1 - 0.11 11.1 3.1 0.16 10.5 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KPI40853.1 - 0.69 9.4 7.2 1.5 8.3 7.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KPI40853.1 - 3.4 6.9 11.3 5.7 6.2 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FA_hydroxylase PF04116.13 KPI40854.1 - 6.5e-20 71.8 13.0 6.5e-20 71.8 13.0 2.3 1 1 2 3 3 3 1 Fatty acid hydroxylase superfamily Phos_pyr_kin PF08543.12 KPI40856.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KPI40856.1 - 1.3e-05 24.7 0.0 2.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Diphthamide_syn PF01866.17 KPI40857.1 - 6.6e-106 354.1 0.0 1.3e-104 349.9 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Peptidase_M20 PF01546.28 KPI40858.1 - 4.4e-28 98.4 0.3 6.5e-28 97.8 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KPI40858.1 - 0.00023 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 KPI40858.1 - 0.00061 19.7 0.5 0.0015 18.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Bromodomain PF00439.25 KPI40859.1 - 1.6e-39 133.8 4.2 1.6e-19 69.8 0.1 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KPI40859.1 - 1.3e-18 66.9 0.1 4.2e-18 65.3 0.1 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 KPI40859.1 - 0.0098 15.9 6.3 0.0098 15.9 6.3 2.9 2 0 0 2 2 2 1 FlxA-like protein Not3 PF04065.15 KPI40859.1 - 0.041 13.3 7.0 0.1 12.0 7.0 1.6 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component AAA_13 PF13166.6 KPI40859.1 - 0.15 10.7 6.0 0.26 9.9 6.0 1.3 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 KPI40859.1 - 1.1 9.7 11.2 0.25 11.7 5.6 2.9 3 0 0 3 3 3 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 KPI40859.1 - 1.4 6.7 3.2 2.4 6.0 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.17 KPI40859.1 - 5.4 6.9 6.4 41 4.1 2.9 2.8 3 0 0 3 3 3 0 Prefoldin subunit AAA PF00004.29 KPI40860.1 - 1.3e-16 61.2 0.0 3.4e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI40860.1 - 0.00065 20.0 0.4 0.0076 16.5 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KPI40860.1 - 0.0029 17.6 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI40860.1 - 0.007 16.8 0.7 0.007 16.8 0.7 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KPI40860.1 - 0.17 11.6 0.0 0.17 11.6 0.0 4.0 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KPI40862.1 - 6.4e-17 61.5 33.7 2.5e-09 36.5 10.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPI40862.1 - 0.027 12.7 2.8 5.1 5.3 0.0 3.6 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF3290 PF11694.8 KPI40862.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) SHR-BD PF06650.12 KPI40863.1 - 3.3e-96 321.8 0.0 3.8e-94 315.1 0.0 3.3 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KPI40863.1 - 8.2e-91 303.6 16.6 1.5e-86 289.7 0.7 5.7 7 0 0 7 7 7 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KPI40863.1 - 4.8e-81 272.0 3.7 1.8e-79 266.9 0.0 3.7 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KPI40863.1 - 1.9e-75 252.6 4.5 4e-71 238.5 0.4 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KPI40863.1 - 2.2e-39 134.2 0.1 2.2e-39 134.2 0.1 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KPI40863.1 - 5.4e-08 33.1 0.2 1.6e-06 28.3 0.0 3.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 KPI40863.1 - 0.19 11.7 5.6 7.2 6.6 0.9 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Ald_Xan_dh_C2 PF02738.18 KPI40864.1 - 3.1e-206 686.1 1.8 4.8e-206 685.5 1.8 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KPI40864.1 - 3.2e-46 157.2 0.0 7.7e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KPI40864.1 - 8.7e-34 115.8 0.8 5.6e-33 113.2 0.0 2.9 4 0 0 4 4 4 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KPI40864.1 - 1.2e-30 106.1 0.0 3.6e-30 104.6 0.0 1.9 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KPI40864.1 - 5.8e-30 103.1 0.1 1.5e-29 101.8 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain p450 PF00067.22 KPI40864.1 - 3.6e-20 72.2 0.0 9.6e-19 67.5 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Fer2 PF00111.27 KPI40864.1 - 9.3e-08 31.9 2.3 1.3e-07 31.5 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MLANA PF14991.6 KPI40865.1 - 2.1 8.7 5.8 1.4 9.2 2.0 2.3 2 1 0 2 2 2 0 Protein melan-A DUF1345 PF07077.11 KPI40865.1 - 3.3 7.4 8.7 0.91 9.2 2.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) Sugar_tr PF00083.24 KPI40867.1 - 3.4e-92 309.7 27.4 3.8e-92 309.5 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40867.1 - 1.3e-25 90.1 28.7 1.3e-25 90.1 28.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Cons_hypoth698 PF03601.14 KPI40867.1 - 0.0025 16.8 4.3 0.0054 15.6 4.3 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 698 Ribosomal_S6e PF01092.19 KPI40868.1 - 1.1e-50 170.8 0.1 1.9e-48 163.6 0.1 2.5 1 1 0 1 1 1 1 Ribosomal protein S6e MFS_1 PF07690.16 KPI40869.1 - 2e-34 119.1 39.0 2e-34 119.1 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 KPI40870.1 - 2.5e-61 207.7 5.2 8.3e-61 206.0 5.2 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.13 KPI40870.1 - 0.35 11.1 15.9 0.2 11.9 7.2 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF456) Chorismate_bind PF00425.18 KPI40871.1 - 3.6e-90 302.0 0.0 7.9e-90 300.9 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KPI40871.1 - 5.3e-28 98.0 0.0 6e-25 88.1 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Ribosomal_L7Ae PF01248.26 KPI40871.1 - 4.8e-21 74.3 0.8 8.2e-21 73.5 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KPI40871.1 - 0.00085 19.4 0.1 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 RNase P subunit Pop3 POR PF01558.18 KPI40871.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Amino_oxidase PF01593.24 KPI40872.1 - 3.2e-21 76.1 0.0 1.2e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI40872.1 - 3.5e-12 46.3 0.0 7.9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI40872.1 - 1.7e-07 31.3 0.0 0.0034 17.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI40872.1 - 0.0018 17.6 0.0 0.1 11.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40872.1 - 0.0067 16.0 0.1 0.022 14.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI40872.1 - 0.0077 15.0 0.1 0.26 9.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Ntox47 PF15540.6 KPI40872.1 - 0.023 15.0 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 47 Pyr_redox PF00070.27 KPI40872.1 - 0.026 15.1 0.1 0.21 12.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI40872.1 - 0.029 13.6 0.1 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI40872.1 - 0.053 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 KPI40872.1 - 0.076 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DUF1297 PF06973.12 KPI40872.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) MRG PF05712.13 KPI40873.1 - 2e-54 183.9 0.0 3e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KPI40873.1 - 1.1e-08 34.8 0.4 2.6e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Presenilin PF01080.17 KPI40873.1 - 0.46 9.2 2.6 0.61 8.8 2.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4470 PF14737.6 KPI40874.1 - 9.8e-19 67.4 0.2 2.1e-18 66.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KPI40874.1 - 0.00032 20.7 7.7 0.00032 20.7 7.7 2.2 2 0 0 2 2 2 1 MYND finger zf-RanBP PF00641.18 KPI40876.1 - 3e-18 64.8 11.1 1.4e-10 40.3 2.0 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KPI40876.1 - 1.4e-07 31.3 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KPI40876.1 - 1.9e-07 31.7 0.0 2.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 KPI40876.1 - 1.3 8.5 4.7 1.2 8.7 0.4 2.7 3 0 0 3 3 3 0 zinc-ribbon domain p450 PF00067.22 KPI40877.1 - 4.1e-67 226.9 0.0 6.5e-67 226.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.18 KPI40877.1 - 7.6e-54 182.7 0.0 1.1e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Phage_endo_I PF05367.11 KPI40877.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage endonuclease I Calcipressin PF04847.12 KPI40878.1 - 3.1e-36 124.9 0.4 4.7e-36 124.3 0.4 1.2 1 0 0 1 1 1 1 Calcipressin Cation_ATPase_N PF00690.26 KPI40879.1 - 0.031 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus F-box-like PF12937.7 KPI40879.1 - 0.051 13.5 0.4 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 F-box-like HORMA PF02301.18 KPI40881.1 - 2.7e-37 128.4 0.0 4.5e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KPI40881.1 - 3.5e-05 23.6 9.4 7.4e-05 22.6 9.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KPI40881.1 - 0.066 12.8 4.3 0.15 11.7 4.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 KPI40881.1 - 0.19 11.4 4.6 0.48 10.0 4.6 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain MMgT PF10270.9 KPI40882.1 - 0.089 13.1 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Membrane magnesium transporter WD40 PF00400.32 KPI40883.1 - 3.6e-41 138.4 12.8 6.8e-06 26.7 0.2 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KPI40883.1 - 1.1e-11 44.4 0.2 2.4e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI40883.1 - 1.8e-10 40.4 0.1 3.8e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KPI40883.1 - 5.6e-06 26.6 2.2 6.8 7.1 0.0 5.9 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KPI40883.1 - 0.0049 16.7 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 KPI40883.1 - 0.011 14.4 5.7 12 4.4 0.0 5.2 6 1 1 7 7 7 0 Nucleoporin Nup120/160 LEA_6 PF10714.9 KPI40883.1 - 0.047 13.7 0.5 0.12 12.4 0.5 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 TFA2_Winged_2 PF18121.1 KPI40885.1 - 5.9e-16 57.9 0.0 1.4e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KPI40885.1 - 0.038 14.3 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF5571 PF17732.1 KPI40885.1 - 0.052 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5571) PA_decarbox PF05870.11 KPI40886.1 - 7.7e-06 25.6 2.1 2e-05 24.2 2.1 1.8 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Pyr_redox_2 PF07992.14 KPI40886.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YrhK PF14145.6 KPI40887.1 - 0.14 12.0 1.4 0.38 10.6 0.4 2.2 1 1 1 2 2 2 0 YrhK-like protein HET PF06985.11 KPI40889.1 - 2.1e-06 28.1 0.0 7.2e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 KPI40890.1 - 6.8e-67 225.9 0.0 1.1e-66 225.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KPI40890.1 - 1.8e-55 187.9 0.0 3.5e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KPI40890.1 - 2.2e-07 30.6 0.0 6.3e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KPI40890.1 - 2.9e-07 30.8 0.0 7.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KPI40890.1 - 2.3e-06 28.5 0.0 3e-05 24.9 0.0 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KPI40890.1 - 2.5e-06 26.5 0.0 0.00019 20.3 0.0 2.3 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 KPI40890.1 - 0.0004 19.5 0.0 0.0024 16.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M41 PF01434.18 KPI40891.1 - 9.4e-54 182.2 0.1 1.8e-53 181.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KPI40891.1 - 2.2e-42 144.6 0.0 5.5e-42 143.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI40891.1 - 3.3e-09 36.4 1.1 8.3e-09 35.1 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KPI40891.1 - 8e-06 25.9 0.0 2.3e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI40891.1 - 5e-05 23.8 0.2 0.00056 20.3 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KPI40891.1 - 5.1e-05 23.6 0.1 0.015 15.5 0.1 2.9 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KPI40891.1 - 0.00094 18.5 0.1 0.0024 17.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KPI40891.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KPI40891.1 - 0.002 17.9 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPI40891.1 - 0.0033 17.6 0.0 0.0095 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KPI40891.1 - 0.0042 16.5 0.2 0.009 15.4 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KPI40891.1 - 0.0051 17.3 0.1 0.028 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KPI40891.1 - 0.016 14.4 0.0 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KPI40891.1 - 0.017 14.7 0.4 0.31 10.6 0.2 2.4 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KPI40891.1 - 0.021 14.7 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KPI40891.1 - 0.023 15.0 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI40891.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KPI40891.1 - 0.06 13.8 0.7 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KPI40891.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KPI40891.1 - 0.088 12.1 1.5 0.29 10.4 0.5 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KPI40891.1 - 0.21 11.1 0.1 0.6 9.6 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Amidohydro_1 PF01979.20 KPI40893.1 - 8.4e-22 77.9 0.0 2.5e-21 76.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI40893.1 - 5.1e-11 42.7 0.9 2e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 KPI40894.1 - 4.1e-24 85.2 50.9 1.1e-23 83.8 51.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.11 KPI40894.1 - 0.34 10.7 0.8 0.78 9.5 0.8 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) F-box PF00646.33 KPI40896.1 - 0.00013 21.7 1.0 0.00021 21.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPI40896.1 - 0.0015 18.4 0.3 0.0071 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KPI40896.1 - 0.077 12.9 0.2 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 F-box NUDIX PF00293.28 KPI40897.1 - 1.4e-18 67.2 0.7 1.7e-18 66.9 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain adh_short PF00106.25 KPI40898.1 - 1.1e-11 44.6 0.0 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40898.1 - 0.0046 16.6 0.0 0.042 13.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pex14_N PF04695.13 KPI40898.1 - 1.5 9.5 7.8 0.82 10.3 5.2 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FBPase PF00316.20 KPI40899.1 - 5.6e-67 224.9 0.0 7.2e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KPI40899.1 - 0.064 12.8 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Inositol monophosphatase family MFS_1 PF07690.16 KPI40900.1 - 4.8e-34 117.8 18.9 5.3e-18 65.1 8.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI40900.1 - 0.0022 16.9 20.3 0.041 12.8 9.1 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_5 PF05631.14 KPI40900.1 - 0.0024 16.8 3.5 0.0045 16.0 3.5 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KPI40900.1 - 0.0033 16.3 17.4 0.0058 15.5 8.1 2.7 2 2 1 3 3 3 2 MFS_1 like family OATP PF03137.20 KPI40900.1 - 0.016 13.5 8.6 1.1 7.5 4.3 3.0 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KPI40900.1 - 0.15 10.4 11.8 0.65 8.3 2.6 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector Acyl-CoA_dh_1 PF00441.24 KPI40902.1 - 4.9e-34 117.7 0.3 6.6e-34 117.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI40902.1 - 8.8e-24 83.5 0.0 1.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI40902.1 - 2.6e-08 34.2 0.2 4e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Nup96 PF12110.8 KPI40903.1 - 4.7e-49 167.1 0.1 6.3e-49 166.7 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KPI40903.1 - 1.4e-45 155.1 0.0 2.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KPI40903.1 - 4.9e-34 117.0 269.1 3.9e-10 40.5 34.4 11.2 4 2 7 11 11 11 7 Nucleoporin FG repeat region LPD11 PF18824.1 KPI40904.1 - 0.0097 16.0 0.2 0.56 10.3 0.0 2.3 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 11 SLAC1 PF03595.17 KPI40905.1 - 1e-50 172.8 46.0 1.3e-50 172.6 46.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Bac_luciferase PF00296.20 KPI40906.1 - 7.4e-51 173.4 0.1 1.3e-48 166.0 0.1 2.1 1 1 0 1 1 1 1 Luciferase-like monooxygenase Fungal_trans_2 PF11951.8 KPI40907.1 - 1.8e-15 56.7 0.1 8.1e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Hexapep PF00132.24 KPI40908.1 - 3.4e-14 51.9 8.0 3.4e-06 26.6 1.1 4.3 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPI40908.1 - 5.7e-08 32.4 0.2 0.002 17.8 0.0 3.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Nop14 PF04147.12 KPI40909.1 - 0.19 9.9 13.7 0.22 9.7 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KPI40909.1 - 0.96 8.7 11.9 0.98 8.7 11.9 1.1 1 0 0 1 1 1 0 BUD22 Dicty_REP PF05086.12 KPI40909.1 - 2.3 6.1 8.5 2.9 5.8 8.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPL5 PF18168.1 KPI40909.1 - 6.1 6.0 6.4 7.9 5.7 6.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Cep57_CLD_2 PF14197.6 KPI40910.1 - 0.1 12.7 4.9 0.17 12.0 0.4 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Hemerythrin PF01814.23 KPI40910.1 - 0.14 12.7 4.8 0.37 11.4 0.3 2.9 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain ADH_zinc_N PF00107.26 KPI40911.1 - 5.8e-17 61.9 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI40911.1 - 9.8e-13 48.0 0.0 3.1e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KPI40911.1 - 3.9e-05 24.7 0.0 7.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.28 KPI40912.1 - 1.2e-78 264.6 0.1 1.7e-78 264.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI40912.1 - 1.6e-27 96.2 0.0 2.2e-26 92.6 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KPI40912.1 - 3.2e-18 65.4 0.1 8.3e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Ank_2 PF12796.7 KPI40913.1 - 2.9e-12 47.0 0.6 4.6e-05 23.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI40913.1 - 5e-11 42.9 0.3 1.8e-06 28.4 0.1 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI40913.1 - 1.9e-10 40.0 0.3 0.0056 17.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KPI40913.1 - 1.4e-08 34.9 0.3 0.00019 21.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPI40913.1 - 5.8e-07 29.7 0.9 0.089 13.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KPI40913.1 - 0.0076 16.1 4.1 0.014 15.2 0.5 2.7 2 1 0 2 2 2 1 KilA-N domain HAP1_N PF04849.13 KPI40913.1 - 0.043 13.0 18.9 0.41 9.8 0.6 2.2 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SpoIIIAH PF12685.7 KPI40913.1 - 0.053 13.4 5.8 0.12 12.2 5.8 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein HAUS6_N PF14661.6 KPI40913.1 - 0.074 12.6 10.4 1.7 8.2 6.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus AAA_13 PF13166.6 KPI40913.1 - 0.12 11.0 7.5 0.015 13.9 2.9 1.7 2 0 0 2 2 2 0 AAA domain THOC7 PF05615.13 KPI40913.1 - 0.2 12.0 16.5 0.063 13.6 10.7 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 KPI40913.1 - 0.77 9.1 8.7 0.9 8.8 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 KPI40913.1 - 0.78 9.3 10.0 0.23 11.0 6.5 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 KPI40913.1 - 1.2 7.7 7.6 0.76 8.3 2.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 KPI40913.1 - 7.3 6.9 21.0 1.4 9.3 10.7 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) HAD PF12710.7 KPI40914.1 - 0.00053 20.4 0.1 0.0013 19.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI40914.1 - 0.18 12.1 0.0 0.47 10.7 0.0 1.5 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase FMO-like PF00743.19 KPI40915.1 - 3.7e-17 61.9 0.0 6.9e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI40915.1 - 5.2e-13 48.8 0.8 3.8e-10 39.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI40915.1 - 4e-12 46.0 0.3 5.6e-11 42.2 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI40915.1 - 1.7e-11 43.9 0.0 6.3e-08 32.2 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI40915.1 - 2.7e-07 30.5 0.3 7.2e-06 25.8 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI40915.1 - 7e-07 29.4 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI40915.1 - 6.5e-06 26.2 0.1 0.0014 18.7 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KPI40915.1 - 0.00059 19.9 0.0 0.058 13.5 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KPI40915.1 - 0.00084 18.7 0.6 0.11 11.8 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 KPI40915.1 - 0.0033 16.7 0.1 0.0063 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KPI40915.1 - 0.13 11.6 0.0 0.72 9.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ldi PF18566.1 KPI40916.1 - 8e-132 439.5 0.2 9.8e-132 439.3 0.2 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase SAPS PF04499.15 KPI40920.1 - 1.3e-80 271.6 2.1 1.8e-80 271.1 0.0 2.0 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein TMEM135_C_rich PF15982.5 KPI40921.1 - 4e-06 27.5 0.7 1.8e-05 25.4 0.3 2.3 3 1 0 3 3 3 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF2863 PF11062.8 KPI40921.1 - 0.19 10.1 0.0 0.29 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Glyco_transf_90 PF05686.12 KPI40922.1 - 2.2e-14 53.2 11.7 8.5e-14 51.3 7.5 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 Flavodoxin_4 PF12682.7 KPI40922.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin RabGAP-TBC PF00566.18 KPI40923.1 - 3.8e-48 164.0 0.1 7.2e-47 159.8 0.2 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ApoO PF09769.9 KPI40923.1 - 0.19 11.7 0.9 0.65 10.0 0.9 1.9 1 0 0 1 1 1 0 Apolipoprotein O Csm2_III-A PF03750.13 KPI40923.1 - 0.2 12.5 13.1 0.37 11.6 2.2 2.8 1 1 1 2 2 2 0 Csm2 Type III-A Fibin PF15819.5 KPI40923.1 - 0.29 10.9 5.5 3 7.6 3.1 2.5 2 0 0 2 2 2 0 Fin bud initiation factor homologue DUF2396 PF09654.10 KPI40923.1 - 0.81 9.8 4.3 1.5 8.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) DUF724 PF05266.14 KPI40923.1 - 1.4 8.7 25.3 0.84 9.4 13.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Zn_clus PF00172.18 KPI40924.1 - 4.1e-09 36.4 10.2 9.5e-09 35.3 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG16 PF08614.11 KPI40925.1 - 0.0027 18.0 10.5 0.011 15.9 10.5 1.9 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Med9 PF07544.13 KPI40925.1 - 0.043 13.9 1.3 0.18 11.9 0.6 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 KPI40925.1 - 0.044 14.1 1.9 1.5 9.1 0.1 2.4 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.11 KPI40925.1 - 0.048 13.5 0.4 0.072 12.9 0.4 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SHE3 PF17078.5 KPI40925.1 - 0.055 13.2 2.7 0.097 12.4 2.7 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 PolyA_pol PF01743.20 KPI40925.1 - 0.072 13.5 3.0 0.37 11.2 2.8 2.2 1 1 0 1 1 1 0 Poly A polymerase head domain DUF4618 PF15397.6 KPI40925.1 - 0.087 12.2 5.5 0.09 12.2 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HAP1_N PF04849.13 KPI40925.1 - 0.094 11.9 8.6 0.14 11.3 8.6 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region MutS_III PF05192.18 KPI40925.1 - 0.15 12.3 1.8 0.23 11.6 1.5 1.5 2 0 0 2 2 1 0 MutS domain III Phage_GPO PF05929.11 KPI40925.1 - 0.23 11.1 4.4 0.33 10.6 4.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Nup54 PF13874.6 KPI40925.1 - 0.29 11.3 9.1 20 5.3 8.6 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 bZIP_1 PF00170.21 KPI40925.1 - 0.3 11.2 1.6 0.48 10.6 0.5 1.9 2 0 0 2 2 2 0 bZIP transcription factor LTXXQ PF07813.12 KPI40925.1 - 0.31 11.8 8.1 0.38 11.5 1.4 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein DUF1664 PF07889.12 KPI40925.1 - 0.34 11.0 4.3 1.5 8.9 1.7 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med21 PF11221.8 KPI40925.1 - 0.43 10.8 6.4 1.2 9.4 6.4 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Acetyltransf_11 PF13720.6 KPI40925.1 - 0.47 11.0 2.1 5.3 7.6 0.3 2.4 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TMPIT PF07851.13 KPI40925.1 - 0.6 9.3 2.3 0.64 9.2 1.8 1.4 1 1 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 KPI40925.1 - 0.81 9.8 8.2 1.5 8.9 8.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Wtap PF17098.5 KPI40925.1 - 3.2 7.7 8.5 4.5 7.2 1.1 2.6 2 1 2 4 4 4 0 WTAP/Mum2p family CENP-F_leu_zip PF10473.9 KPI40925.1 - 4.1 7.4 9.3 1.7e+02 2.2 8.9 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KPI40925.1 - 5.1 7.3 7.3 1.2 9.2 2.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 KPI40925.1 - 9.3 6.8 8.5 0.98 9.9 0.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Inhibitor_I9 PF05922.16 KPI40926.1 - 0.0013 19.3 0.1 0.0016 19.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 SET PF00856.28 KPI40927.1 - 0.0076 16.7 0.0 0.019 15.4 0.0 1.7 2 0 0 2 2 2 1 SET domain HET PF06985.11 KPI40928.1 - 1.2e-10 41.9 1.1 5.4e-09 36.6 0.0 2.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KPI40928.1 - 1.9e-06 28.3 0.2 0.0023 18.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) NACHT PF05729.12 KPI40928.1 - 2.8e-05 24.1 0.0 7.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPI40928.1 - 3.1e-05 24.4 0.6 0.00026 21.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Ank_4 PF13637.6 KPI40928.1 - 0.00045 20.7 0.1 0.047 14.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 KPI40928.1 - 0.0026 18.0 0.0 0.011 16.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI40928.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI40928.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 KPI40929.1 - 1.9e-21 76.0 0.0 1.9e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Nuc_sug_transp PF04142.15 KPI40930.1 - 1.1e-93 313.9 11.8 1.4e-93 313.6 11.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KPI40930.1 - 3.4e-05 24.0 14.7 3.4e-05 24.0 14.7 3.3 2 2 0 2 2 2 1 EamA-like transporter family EmrE PF13536.6 KPI40930.1 - 0.00068 19.3 1.4 0.00068 19.3 1.4 3.0 2 1 1 3 3 3 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 KPI40930.1 - 0.0017 17.7 5.6 0.0017 17.7 5.6 3.0 2 1 2 4 4 4 1 Purine nucleobase transmembrane transport TPT PF03151.16 KPI40930.1 - 0.0021 17.5 5.3 0.0021 17.5 5.3 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family TMEM234 PF10639.9 KPI40930.1 - 0.3 11.1 9.8 0.032 14.3 3.3 2.5 2 1 0 2 2 2 0 Putative transmembrane family 234 UAA PF08449.11 KPI40930.1 - 0.36 10.0 22.8 0.019 14.2 7.8 3.1 2 2 0 2 2 2 0 UAA transporter family DMT_6 PF04342.12 KPI40930.1 - 7.3 6.9 11.2 1.2 9.4 5.1 2.6 2 1 0 2 2 2 0 Putative member of DMT superfamily (DUF486) C2 PF00168.30 KPI40931.1 - 3e-28 98.1 0.1 3e-16 59.6 0.0 3.1 3 0 0 3 3 3 2 C2 domain Spermine_synth PF01564.17 KPI40932.1 - 1.8e-71 239.4 0.0 3.8e-71 238.4 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KPI40932.1 - 2.5e-20 72.1 0.0 4.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KPI40932.1 - 0.00024 21.7 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI40932.1 - 0.0005 19.9 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KPI40932.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KPI40932.1 - 0.0029 18.3 0.2 0.019 15.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KPI40932.1 - 0.045 13.4 0.0 0.079 12.6 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KPI40932.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Myb_DNA-binding PF00249.31 KPI40932.1 - 0.16 12.2 0.1 0.43 10.8 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain DSBA PF01323.20 KPI40934.1 - 1.2e-29 103.4 0.0 1.5e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KPI40934.1 - 0.08 13.1 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin DIOX_N PF14226.6 KPI40935.1 - 2.9e-27 95.7 0.2 6.9e-27 94.5 0.1 1.7 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI40935.1 - 2.2e-18 66.6 0.0 4.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WAK_assoc PF14380.6 KPI40936.1 - 0.014 16.1 0.1 0.034 14.9 0.1 1.6 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal DUF4128 PF13554.6 KPI40936.1 - 0.07 13.2 1.6 0.11 12.5 0.4 1.9 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function DHBP_synthase PF00926.19 KPI40937.1 - 9.2e-83 276.5 0.2 1.1e-82 276.3 0.2 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Epimerase PF01370.21 KPI40938.1 - 0.0026 17.2 0.0 0.01 15.3 0.0 2.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI40938.1 - 0.21 10.7 0.0 6.8 5.8 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein SnoaL_2 PF12680.7 KPI40939.1 - 0.00095 19.8 0.1 0.0011 19.5 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain ACAS_N PF16177.5 KPI40939.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus DUF720 PF05302.11 KPI40940.1 - 0.0039 17.0 11.0 0.0064 16.3 11.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF720) Tis11B_N PF04553.12 KPI40940.1 - 0.027 15.0 1.0 0.027 15.0 1.0 1.6 2 0 0 2 2 2 0 Tis11B like protein, N terminus TFIIA PF03153.13 KPI40940.1 - 5.6 6.9 20.6 7.5 6.4 20.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Meth_synt_2 PF01717.18 KPI40941.1 - 4.9e-10 39.2 0.0 0.016 14.5 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPI40941.1 - 0.038 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain DUF2173 PF09941.9 KPI40941.1 - 0.081 13.2 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) MFS_1 PF07690.16 KPI40942.1 - 1.2e-34 119.8 36.3 1.7e-34 119.3 36.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 KPI40942.1 - 0.058 13.7 2.7 0.43 10.9 0.1 3.2 2 0 0 2 2 2 0 Transglycosylase associated protein Sugar_tr PF00083.24 KPI40942.1 - 0.13 11.1 34.9 1.1 8.0 11.5 2.5 1 1 1 2 2 2 0 Sugar (and other) transporter AMP-binding PF00501.28 KPI40943.1 - 1.4e-79 267.7 0.1 3.3e-79 266.5 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI40943.1 - 1e-12 48.9 0.1 4.7e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sld5 PF05916.11 KPI40944.1 - 2.9e-18 66.3 0.0 3.6e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Nitro_FeMo-Co PF02579.17 KPI40946.1 - 0.046 14.1 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DSBA PF01323.20 KPI40947.1 - 1.2e-45 155.7 0.0 3e-21 76.1 0.0 3.0 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 KPI40947.1 - 0.0044 16.7 0.0 0.0073 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin NAC PF01849.18 KPI40948.1 - 3.8e-23 81.2 0.0 1.7e-22 79.1 0.0 2.0 2 0 0 2 2 2 1 NAC domain RNA_pol_3_Rpc31 PF11705.8 KPI40948.1 - 0.55 10.4 11.4 0.03 14.6 1.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 KPI40948.1 - 1.1 9.6 10.6 11 6.5 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PGA2 PF07543.12 KPI40948.1 - 1.2 9.1 13.3 5.9 6.9 7.7 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 CFIA_Pcf11 PF11526.8 KPI40948.1 - 2.9 8.4 7.5 1.4 9.5 3.1 2.5 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 DUF4746 PF15928.5 KPI40948.1 - 3.6 6.9 8.0 3 7.2 5.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Cwf_Cwc_15 PF04889.12 KPI40948.1 - 7.9 6.1 15.3 3.3 7.4 7.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rgp1 PF08737.10 KPI40950.1 - 2.6e-103 346.4 0.0 8.6e-73 245.9 0.0 2.6 1 1 1 2 2 2 2 Rgp1 Arrestin_N PF00339.29 KPI40950.1 - 0.00081 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Epimerase PF01370.21 KPI40951.1 - 2.6e-10 40.2 0.1 2.5e-09 37.0 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI40951.1 - 4.2e-05 23.5 0.0 8e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI40951.1 - 0.00048 19.8 0.0 0.002 17.8 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.12 KPI40951.1 - 0.0093 15.2 0.1 0.072 12.3 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KPI40951.1 - 0.022 14.1 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MutL_C PF08676.11 KPI40952.1 - 3.7e-23 81.9 0.0 2.6e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KPI40952.1 - 4e-20 71.7 0.0 1.8e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KPI40952.1 - 8.6e-10 38.6 0.0 2.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPI40952.1 - 2.7e-06 27.9 0.0 8.6e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SabA_adhesion PF18304.1 KPI40952.1 - 0.18 11.0 0.5 0.35 10.1 0.5 1.4 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain DUF3813 PF12758.7 KPI40952.1 - 0.35 11.2 6.6 0.51 10.7 4.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) DUF3429 PF11911.8 KPI40953.1 - 1e-43 149.0 13.0 1.4e-43 148.6 13.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) CTP_transf_1 PF01148.20 KPI40954.1 - 5.7e-79 265.6 21.3 5.7e-79 265.6 21.3 3.3 3 0 0 3 3 3 1 Cytidylyltransferase family AA_permease_2 PF13520.6 KPI40954.1 - 3.7e-45 154.5 51.8 3.7e-45 154.5 51.8 3.0 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KPI40954.1 - 1.4e-21 76.7 44.3 1.4e-21 76.7 44.3 2.2 2 1 0 2 2 2 1 Amino acid permease Shisa PF13908.6 KPI40954.1 - 0.14 12.4 0.9 15 5.8 0.1 3.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.16 KPI40956.1 - 1.7e-33 116.1 19.9 2.5e-33 115.5 19.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box_4 PF15966.5 KPI40956.1 - 0.083 12.8 0.1 0.4 10.6 0.0 2.1 3 0 0 3 3 3 0 F-box Glucosaminidase PF01832.20 KPI40956.1 - 0.087 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CDP-OH_P_tran_2 PF08009.11 KPI40956.1 - 0.34 10.9 5.5 0.56 10.2 1.5 3.0 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 DUF3328 PF11807.8 KPI40957.1 - 6.9e-35 120.8 0.4 8.6e-35 120.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 KPI40958.1 - 1.3e-40 140.1 0.4 2.9e-40 138.9 0.4 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KPI40958.1 - 3.5e-30 105.2 0.0 6.7e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain 4HBT_3 PF13622.6 KPI40959.1 - 3.7e-37 128.9 1.3 4.8e-37 128.6 1.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KPI40959.1 - 2.2e-08 34.0 0.0 5.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA thioesterase Pectate_lyase PF03211.13 KPI40960.1 - 6.9e-37 127.0 2.0 8.9e-37 126.6 2.0 1.1 1 0 0 1 1 1 1 Pectate lyase AAA PF00004.29 KPI40961.1 - 4.2e-37 127.5 0.0 1.1e-36 126.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI40961.1 - 8.4e-10 38.3 1.8 2.5e-09 36.8 0.2 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KPI40961.1 - 2.7e-05 24.6 0.3 0.001 19.5 0.3 3.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KPI40961.1 - 2.9e-05 24.2 0.1 0.0049 17.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI40961.1 - 0.00023 21.4 0.1 0.055 13.7 0.1 3.5 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KPI40961.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KPI40961.1 - 0.0037 17.4 0.0 0.0098 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KPI40961.1 - 0.0062 16.6 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KPI40961.1 - 0.0091 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KPI40961.1 - 0.0096 15.9 0.0 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KPI40961.1 - 0.018 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KPI40961.1 - 0.025 15.0 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.6 KPI40961.1 - 0.025 15.1 0.2 0.11 13.0 0.0 2.3 3 0 0 3 3 1 0 AAA domain TIP49 PF06068.13 KPI40961.1 - 0.051 12.8 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KPI40961.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI40961.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KPI40961.1 - 0.19 11.7 0.0 0.53 10.2 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain Hydin_ADK PF17213.3 KPI40961.1 - 0.57 10.4 9.3 7.2 6.8 0.0 3.5 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Glyco_hydro_31 PF01055.26 KPI40962.1 - 1.5e-112 377.1 0.2 1.8e-112 376.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KPI40962.1 - 3.1e-17 62.7 0.2 8.8e-17 61.2 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.16 KPI40963.1 - 5.6e-22 78.1 20.2 5.6e-22 78.1 20.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KPI40963.1 - 1.5e-11 44.2 3.2 1.5e-11 44.2 3.2 1.8 2 0 0 2 2 2 1 Nodulin-like DUF2457 PF10446.9 KPI40963.1 - 0.038 13.1 2.3 0.054 12.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MRP-L27 PF09809.9 KPI40964.1 - 2e-15 56.6 0.2 2.9e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 MgsA_C PF12002.8 KPI40965.1 - 3.3e-54 183.3 0.0 5.2e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KPI40965.1 - 5.2e-18 65.2 0.0 1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KPI40965.1 - 1.7e-15 57.6 0.0 4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPI40965.1 - 1.4e-10 41.1 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPI40965.1 - 1.4e-06 28.4 0.0 1.1e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KPI40965.1 - 1.8e-06 27.5 0.0 0.047 13.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KPI40965.1 - 4.7e-06 26.4 0.0 4.6e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 KPI40965.1 - 2e-05 24.9 0.2 7.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI40965.1 - 5.6e-05 23.6 0.2 0.013 15.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain zf-C2HC_2 PF13913.6 KPI40965.1 - 0.00089 19.1 0.1 0.0023 17.8 0.0 1.7 2 0 0 2 2 1 1 zinc-finger of a C2HC-type AAA_3 PF07726.11 KPI40965.1 - 0.002 18.0 0.0 0.0088 15.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KPI40965.1 - 0.0027 18.2 0.0 0.0055 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KPI40965.1 - 0.0028 17.8 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.13 KPI40965.1 - 0.0045 16.2 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KPI40965.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sgf11 PF08209.11 KPI40965.1 - 0.021 14.4 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) TIP49 PF06068.13 KPI40965.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KPI40965.1 - 0.03 14.7 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.15 KPI40965.1 - 0.036 14.1 0.0 10 6.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KPI40965.1 - 0.057 13.2 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI40965.1 - 0.059 13.1 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPI40965.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KPI40965.1 - 0.093 13.1 0.1 0.42 10.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain SKI PF01202.22 KPI40965.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase zf_C2H2_13 PF18508.1 KPI40965.1 - 0.11 12.1 0.5 0.51 10.0 1.0 1.9 2 0 0 2 2 1 0 Zinc finger domain AAA_33 PF13671.6 KPI40965.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPI40965.1 - 0.14 12.4 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPI40965.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 KPI40965.1 - 0.19 10.8 0.0 0.51 9.4 0.1 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KPI40965.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Cutinase PF01083.22 KPI40966.1 - 8e-32 110.6 1.7 1e-31 110.3 1.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPI40966.1 - 0.014 15.0 0.3 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 KPI40966.1 - 0.079 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 KPI40966.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ferric_reduct PF01794.19 KPI40967.1 - 1e-25 90.3 8.4 1e-25 90.3 8.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPI40967.1 - 8.4e-09 35.7 0.0 3.4e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI40967.1 - 1.9e-07 31.2 0.0 6.3e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KPI40967.1 - 6.2e-06 26.8 0.0 1.2e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short PF00106.25 KPI40968.1 - 5.1e-41 140.3 0.0 6.5e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI40968.1 - 1.4e-35 123.0 0.1 2.3e-35 122.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI40968.1 - 2.1e-11 44.1 0.1 3e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI40968.1 - 0.0093 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI40968.1 - 0.049 13.1 0.3 0.48 9.8 0.3 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KPI40968.1 - 0.14 11.9 0.2 0.33 10.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase His_Phos_2 PF00328.22 KPI40969.1 - 8.1e-09 35.3 0.0 6.3e-06 25.8 0.0 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-C2H2 PF00096.26 KPI40969.1 - 6.9e-06 26.2 14.9 0.0072 16.7 4.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI40969.1 - 9e-06 25.9 6.4 9e-06 25.9 6.4 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI40969.1 - 0.00059 20.5 12.1 0.27 12.2 3.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI40969.1 - 0.0065 16.7 7.5 0.3 11.4 3.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KPI40969.1 - 0.047 13.5 4.6 0.056 13.2 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KPI40969.1 - 1.5 8.8 7.1 2.3 8.2 1.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KPI40969.1 - 4.5 7.2 6.6 2.8 7.9 1.9 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 KPI40969.1 - 4.6 7.8 8.5 9.3 6.8 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Apolipoprotein PF01442.18 KPI40970.1 - 1.9e-06 27.9 41.2 0.00014 21.8 16.6 3.7 2 2 2 4 4 4 2 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 KPI40970.1 - 1.2e-05 25.4 11.7 1.2e-05 25.4 11.7 4.3 2 1 2 4 4 4 2 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 KPI40970.1 - 0.0082 15.7 31.1 0.36 10.4 1.7 5.4 2 1 2 5 5 5 3 fzo-like conserved region Baculo_PEP_C PF04513.12 KPI40970.1 - 0.009 16.1 31.8 0.019 15.0 5.6 5.1 2 1 4 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus VirE PF05272.11 KPI40970.1 - 0.054 13.2 2.6 0.64 9.7 0.2 2.8 2 0 0 2 2 2 0 Virulence-associated protein E DUF1664 PF07889.12 KPI40970.1 - 0.076 13.1 36.6 0.13 12.3 2.8 4.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Spore_III_AB PF09548.10 KPI40970.1 - 0.12 12.5 15.1 1.2 9.2 4.9 3.7 2 2 2 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) ApoLp-III PF07464.11 KPI40970.1 - 0.16 12.1 36.0 1.9 8.5 4.5 4.2 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF1394 PF07159.12 KPI40970.1 - 0.42 9.8 9.6 0.053 12.8 0.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1394) DUF2594 PF10769.9 KPI40970.1 - 0.44 10.6 3.2 0.66 10.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2594) HbrB PF08539.11 KPI40970.1 - 3 7.8 6.1 7.2 6.6 0.0 3.1 4 0 0 4 4 4 0 HbrB-like Prominin PF05478.11 KPI40970.1 - 8.3 4.2 26.2 2.1 6.2 16.9 2.8 2 1 1 3 3 3 0 Prominin DnaJ PF00226.31 KPI40971.1 - 2.2e-10 40.5 0.0 4.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 KPI40972.1 - 3e-60 204.4 9.2 3.3e-60 204.2 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40972.1 - 4.5e-28 98.2 14.6 5.7e-28 97.9 14.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0114 PF03350.16 KPI40972.1 - 0.12 12.6 1.1 0.37 11.0 1.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Sclerostin PF05463.11 KPI40972.1 - 0.22 11.2 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 Sclerostin (SOST) ABC2_membrane_4 PF12730.7 KPI40972.1 - 0.25 11.3 6.8 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 ABC-2 family transporter protein UPF0121 PF03661.13 KPI40973.1 - 3.7e-29 101.8 1.2 5e-29 101.4 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF3960 PF13142.6 KPI40975.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) DUF1658 PF07871.11 KPI40976.1 - 1 9.4 3.5 0.82 9.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) AAA_16 PF13191.6 KPI40977.1 - 0.0074 16.7 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KPI40977.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 KPI40977.1 - 0.04 13.7 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KPI40977.1 - 0.047 14.2 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KPI40977.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 KPI40977.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CPT PF07931.12 KPI40977.1 - 0.13 12.0 0.2 0.29 10.9 0.1 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_21 PF13304.6 KPI40977.1 - 0.14 11.9 0.1 0.56 10.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KPI40977.1 - 0.2 11.9 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cupin_2 PF07883.11 KPI40978.1 - 7.8e-09 35.1 0.1 1.3e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPI40978.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Med27 PF11571.8 KPI40979.1 - 2.4e-15 56.7 0.2 5e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 TAF4 PF05236.14 KPI40980.1 - 1e-24 87.8 10.5 7.1e-21 75.2 10.2 2.1 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family RR_TM4-6 PF06459.12 KPI40980.1 - 0.066 13.0 8.2 0.14 12.0 8.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Questin_oxidase PF14027.6 KPI40980.1 - 2.3 7.7 5.9 3.4 7.1 5.9 1.2 1 0 0 1 1 1 0 Questin oxidase-like MAJIN PF15077.6 KPI40980.1 - 5.3 6.7 6.5 11 5.7 6.5 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein GREB1 PF15782.5 KPI40980.1 - 5.5 4.0 5.5 7.2 3.6 5.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ADH_N PF08240.12 KPI40981.1 - 3.2e-21 75.3 0.3 5e-21 74.6 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI40981.1 - 6.8e-20 71.4 0.1 1.3e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI40981.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPI40981.1 - 0.018 14.4 1.0 0.026 13.8 1.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KPI40981.1 - 0.084 13.9 0.0 0.18 12.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase XdhC_C PF13478.6 KPI40981.1 - 0.09 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Asp PF00026.23 KPI40982.1 - 6.7e-105 351.0 0.0 7.9e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI40982.1 - 3.1e-15 56.9 0.8 5.4e-13 49.6 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI40982.1 - 0.00025 21.6 0.3 2.1 9.0 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI40982.1 - 0.00091 19.7 0.0 2.4 8.8 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease PhyH PF05721.13 KPI40983.1 - 3e-26 93.0 0.0 5.9e-26 92.0 0.0 1.5 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Hydrolase PF00702.26 KPI40985.1 - 3.6e-09 37.2 0.0 2.7e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPI40985.1 - 1.9e-08 34.6 0.1 3.1e-08 33.9 0.1 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Sulfotransfer_4 PF17784.1 KPI40986.1 - 3.8e-67 226.3 0.0 4.5e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI40986.1 - 0.00022 21.7 0.2 0.0037 17.7 0.1 2.5 1 1 1 2 2 2 1 Sulfotransferase family Protocadherin PF08374.11 KPI40987.1 - 0.055 13.4 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 KPI40987.1 - 0.11 12.4 0.2 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 KPI40987.1 - 0.12 12.6 0.4 0.18 12.0 0.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KPI40987.1 - 0.13 13.2 0.0 0.17 12.8 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KPI40987.1 - 0.16 10.7 0.7 0.21 10.3 0.7 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMIE PF16038.5 KPI40987.1 - 0.21 11.4 1.1 0.32 10.9 1.1 1.2 1 0 0 1 1 1 0 TMIE protein p450 PF00067.22 KPI40988.1 - 1.5e-73 248.2 0.0 1.9e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KPI40989.1 - 7.9e-45 152.8 1.3 1.3e-44 152.1 1.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI40989.1 - 2.3e-27 95.5 0.1 8.7e-27 93.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI40989.1 - 2.7e-07 30.8 0.0 4.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KPI40989.1 - 9e-05 22.3 0.2 0.00016 21.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI40989.1 - 0.0018 18.7 0.7 0.0031 17.9 0.7 1.5 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 KPI40989.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KPI40989.1 - 0.0065 16.8 1.5 0.041 14.2 1.5 2.2 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KPI40989.1 - 0.069 13.0 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Helicase fragilysinNterm PF16376.5 KPI40989.1 - 0.09 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Sugar_tr PF00083.24 KPI40990.1 - 1.2e-101 340.8 17.8 1.4e-101 340.6 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI40990.1 - 2.6e-20 72.7 26.3 6.9e-15 54.8 9.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPI40990.1 - 0.0039 15.5 0.5 0.0039 15.5 0.5 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF697 PF05128.12 KPI40990.1 - 1.1 9.0 3.6 2.1 8.0 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Hist_deacetyl PF00850.19 KPI40991.1 - 2.9e-51 174.8 0.5 4.8e-51 174.1 0.5 1.3 1 0 0 1 1 1 1 Histone deacetylase domain TAF1D PF15333.6 KPI40991.1 - 5.8 6.6 7.5 12 5.5 7.5 1.5 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D AMP-binding PF00501.28 KPI40993.1 - 7.2e-18 64.4 0.0 9.3e-18 64.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Autotransporter PF03797.19 KPI40993.1 - 0.077 12.6 0.3 0.34 10.5 0.3 1.9 1 1 0 1 1 1 0 Autotransporter beta-domain PHP_C PF13263.6 KPI40993.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 PHP-associated Pkinase PF00069.25 KPI40994.1 - 7.1e-73 245.2 0.0 3.2e-72 243.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI40994.1 - 6.7e-44 150.1 0.0 1.1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI40994.1 - 1.6e-06 27.6 0.0 3.9e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPI40994.1 - 0.00062 19.2 0.3 0.0011 18.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPI40994.1 - 0.0011 18.0 0.1 0.0016 17.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KPI40994.1 - 0.005 16.5 0.6 0.072 12.7 0.1 2.3 2 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KPI40994.1 - 0.035 13.7 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KPI40994.1 - 0.044 12.5 0.1 0.091 11.5 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KPI40994.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribonuc_L-PSP PF01042.21 KPI40994.1 - 0.13 12.3 0.5 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 Endoribonuclease L-PSP Cation_ATPase_C PF00689.21 KPI40995.1 - 9.5e-42 142.8 10.5 1.7e-41 141.9 8.1 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPI40995.1 - 7.7e-38 129.8 0.0 2.6e-37 128.1 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KPI40995.1 - 2e-18 67.5 0.1 1.4e-17 64.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPI40995.1 - 2.2e-16 59.7 0.2 8.4e-16 57.8 0.0 2.1 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPI40995.1 - 5.9e-08 32.3 0.0 7.7e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI40995.1 - 7.3e-07 29.2 0.3 2.5e-05 24.1 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFO_IDH_MocA PF01408.22 KPI40996.1 - 4.1e-18 66.3 0.0 6.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Stathmin PF00836.19 KPI40997.1 - 0.02 14.9 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Stathmin family MAGI_u5 PF16666.5 KPI40997.1 - 5.3 7.2 6.7 0.98 9.6 2.5 1.9 1 1 1 2 2 2 0 Unstructured region on MAGI Bap31 PF05529.12 KPI40998.1 - 6.3e-47 158.8 8.6 1e-46 158.2 8.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KPI40998.1 - 1.6e-13 50.4 3.5 2.8e-13 49.6 3.5 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain CEP63 PF17045.5 KPI40998.1 - 0.0021 18.0 1.0 0.0033 17.4 1.0 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa LRRFIP PF09738.9 KPI40998.1 - 0.011 15.2 0.9 0.016 14.7 0.9 1.2 1 0 0 1 1 1 0 LRRFIP family Prefoldin_2 PF01920.20 KPI40998.1 - 0.014 15.4 1.2 0.025 14.5 1.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit ATG16 PF08614.11 KPI40998.1 - 0.028 14.6 0.3 0.046 13.9 0.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TRAF_BIRC3_bd PF16673.5 KPI40998.1 - 0.043 13.6 1.6 0.069 12.9 0.6 1.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF4047 PF13256.6 KPI40998.1 - 0.046 13.9 0.2 0.072 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DivIC PF04977.15 KPI40998.1 - 0.046 13.5 4.0 0.76 9.6 2.1 2.7 2 0 0 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 KPI40998.1 - 0.16 12.3 1.8 0.32 11.3 1.8 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain She9_MDM33 PF05546.11 KPI40998.1 - 0.62 9.8 3.1 0.23 11.2 0.4 1.6 2 0 0 2 2 2 0 She9 / Mdm33 family PQ-loop PF04193.14 KPI41000.1 - 1.1e-27 95.5 0.7 2.3e-19 68.9 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.16 KPI41001.1 - 2.4e-35 122.1 21.3 3.6e-35 121.5 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI41001.1 - 3.3e-08 33.2 0.2 3.3e-08 33.2 0.2 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PEN-2 PF10251.9 KPI41001.1 - 0.64 10.5 0.0 0.64 10.5 0.0 4.6 4 2 1 5 5 5 0 Presenilin enhancer-2 subunit of gamma secretase Snf7 PF03357.21 KPI41002.1 - 1.6e-34 119.0 23.0 1.6e-34 119.0 23.0 2.0 1 1 0 2 2 2 1 Snf7 Calici_MSP PF05752.11 KPI41002.1 - 0.023 14.5 5.9 9 6.1 5.9 2.3 1 1 0 1 1 1 0 Calicivirus minor structural protein Exonuc_VII_L PF02601.15 KPI41002.1 - 0.75 9.3 9.2 0.93 9.0 9.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PIN_8 PF18476.1 KPI41002.1 - 2.3 8.0 10.3 8.2 6.2 10.3 1.8 1 1 0 1 1 1 0 PIN like domain DUF3138 PF11336.8 KPI41002.1 - 3.3 6.2 12.2 2.2 6.8 10.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) SPRY PF00622.28 KPI41003.1 - 1.2e-17 64.1 0.1 1.9e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 SPRY domain DUF3611 PF12263.8 KPI41003.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) COX5B PF01215.19 KPI41005.1 - 3.4e-52 175.5 0.0 4.6e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb PhoD PF09423.10 KPI41006.1 - 2.7e-112 375.3 4.4 3.4e-112 374.9 4.4 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KPI41006.1 - 7.2e-35 119.4 0.1 1.8e-34 118.1 0.1 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KPI41006.1 - 1.1e-05 25.9 1.8 3e-05 24.5 0.5 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain TPP_enzyme_N PF02776.18 KPI41007.1 - 2.7e-54 183.3 0.0 3.4e-53 179.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPI41007.1 - 2.1e-48 164.0 0.6 2.6e-46 157.2 0.0 3.0 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI41007.1 - 2.5e-41 140.6 1.3 5e-41 139.7 0.6 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RICTOR_N PF14664.6 KPI41008.1 - 1.7e-117 392.6 0.5 2.9e-117 391.8 0.5 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KPI41008.1 - 2.6e-34 117.9 2.1 6.6e-33 113.4 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KPI41008.1 - 1.8e-31 107.9 1.4 1.6e-29 101.8 0.1 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KPI41008.1 - 8.9e-25 86.7 2.0 3.3e-21 75.3 0.1 4.0 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KPI41008.1 - 1.6e-08 34.6 6.8 4.4e-08 33.1 6.8 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.6 KPI41008.1 - 9.3 6.9 9.5 41 4.8 0.8 4.4 4 0 0 4 4 4 0 HEAT-like repeat Med19 PF10278.9 KPI41009.1 - 7.3e-05 22.8 10.1 8e-05 22.6 10.1 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.9 KPI41009.1 - 0.00011 21.9 10.6 0.00012 21.8 10.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 KPI41009.1 - 0.092 12.8 15.3 0.11 12.5 15.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNA_pol_Rpc4 PF05132.14 KPI41009.1 - 0.17 12.3 8.5 0.21 12.0 8.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 KPI41009.1 - 0.26 11.6 12.3 0.31 11.4 12.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 KPI41009.1 - 0.27 11.0 7.3 0.3 10.9 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SspB PF04386.13 KPI41009.1 - 0.39 10.6 5.0 0.49 10.3 5.0 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Tim54 PF11711.8 KPI41009.1 - 0.47 9.2 6.7 0.54 9.0 6.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FancD2 PF14631.6 KPI41009.1 - 0.5 7.7 9.4 0.63 7.4 9.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SelP_N PF04592.14 KPI41009.1 - 1.8 7.9 9.4 2.3 7.6 9.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Coilin_N PF15862.5 KPI41009.1 - 1.9 8.3 15.6 2.4 8.0 15.6 1.1 1 0 0 1 1 1 0 Coilin N-terminus RPN2_C PF18004.1 KPI41009.1 - 2 8.4 14.7 2.4 8.0 14.7 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain YqfQ PF14181.6 KPI41009.1 - 2.7 8.2 10.4 3.5 7.8 10.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 KPI41009.1 - 4.7 5.4 10.9 5.4 5.2 10.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KPI41009.1 - 7.8 5.1 9.0 9.2 4.9 9.0 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KPI41009.1 - 8.4 5.5 9.7 11 5.1 9.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Lon_C PF05362.13 KPI41010.1 - 1.8e-66 223.6 0.0 3.1e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KPI41010.1 - 3.1e-33 115.4 0.1 7e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KPI41010.1 - 1.5e-22 80.4 0.0 1.8e-21 76.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPI41010.1 - 7.6e-07 29.2 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KPI41010.1 - 2.1e-06 28.0 0.0 6.5e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KPI41010.1 - 3.4e-06 26.9 0.0 1.3e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KPI41010.1 - 2e-05 24.9 0.1 0.00064 20.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KPI41010.1 - 4.1e-05 22.7 0.0 8.4e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KPI41010.1 - 0.00018 21.3 0.0 0.00071 19.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI41010.1 - 0.0021 18.5 0.1 0.0021 18.5 0.1 2.8 3 1 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 KPI41010.1 - 0.021 14.8 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4276 PF14103.6 KPI41010.1 - 0.026 14.8 3.7 0.28 11.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4276) IstB_IS21 PF01695.17 KPI41010.1 - 0.026 14.2 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KPI41010.1 - 0.031 14.7 0.0 0.22 12.0 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_30 PF13604.6 KPI41010.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNTTIP1_dimer PF18192.1 KPI41010.1 - 0.053 13.9 0.6 0.94 9.9 0.3 2.6 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain RsgA_GTPase PF03193.16 KPI41010.1 - 0.06 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KPI41010.1 - 0.069 13.7 0.0 0.069 13.7 0.0 3.0 4 0 0 4 4 2 0 AAA domain SKI PF01202.22 KPI41010.1 - 0.075 13.1 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase CbiA PF01656.23 KPI41010.1 - 0.095 12.8 0.4 1.9 8.5 0.1 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KPI41010.1 - 0.14 11.7 0.8 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KPI41010.1 - 0.14 12.6 1.4 0.87 10.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter DUF445 PF04286.12 KPI41010.1 - 0.33 10.7 4.3 0.22 11.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Eapp_C PF10238.9 KPI41010.1 - 0.8 9.8 3.4 9.7 6.2 0.3 2.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein TauD PF02668.16 KPI41011.1 - 2.1e-54 185.1 0.0 2.5e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KPI41012.1 - 8.6e-77 258.9 19.3 9.9e-77 258.7 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41012.1 - 1.4e-15 57.0 28.4 1.9e-09 36.9 22.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI41012.1 - 8.1 5.2 16.9 0.017 14.0 4.4 2.5 3 1 0 3 3 3 0 MFS_1 like family Whi5 PF08528.11 KPI41013.1 - 1.1e-06 28.1 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like GFO_IDH_MocA PF01408.22 KPI41014.1 - 8.7e-07 29.8 0.0 1.6e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI41014.1 - 0.0049 16.9 0.0 0.021 14.9 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pectate_lyase_3 PF12708.7 KPI41015.1 - 4.3e-87 291.5 11.4 2.3e-73 246.6 1.9 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KPI41015.1 - 4.8e-07 29.4 1.1 0.00053 19.6 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Period_C PF12114.8 KPI41015.1 - 1.3 8.6 0.0 1.3 8.6 0.0 3.0 2 1 0 2 2 2 0 Period protein 2/3C-terminal region BRO1 PF03097.18 KPI41016.1 - 1.6e-130 435.4 4.4 1.8e-130 435.3 4.4 1.0 1 0 0 1 1 1 1 BRO1-like domain MFS_1 PF07690.16 KPI41017.1 - 6.5e-34 117.4 25.4 1.2e-33 116.5 24.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1230 PF06799.11 KPI41017.1 - 0.2 11.7 2.1 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 BTB PF00651.31 KPI41018.1 - 3.7e-09 36.8 0.0 6.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 KPI41018.1 - 0.0041 17.3 0.1 0.0096 16.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) COG5 PF10392.9 KPI41019.1 - 6.7e-26 91.0 3.7 1.7e-25 89.8 3.7 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 GAS PF13851.6 KPI41019.1 - 0.019 14.3 0.6 0.019 14.3 0.6 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ECM11 PF15463.6 KPI41019.1 - 0.025 15.1 0.4 0.064 13.8 0.4 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 DUF3287 PF11690.8 KPI41019.1 - 0.039 13.7 0.4 0.092 12.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) CASP_C PF08172.12 KPI41019.1 - 0.048 13.0 1.1 0.11 11.8 1.1 1.5 1 0 0 1 1 1 0 CASP C terminal DUF724 PF05266.14 KPI41019.1 - 0.12 12.2 2.7 0.2 11.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) YqzL PF14006.6 KPI41019.1 - 0.22 11.9 2.0 0.58 10.6 2.0 1.7 1 0 0 1 1 1 0 YqzL-like protein Tannase PF07519.11 KPI41020.1 - 2.3e-52 178.5 0.2 4.1e-52 177.6 0.2 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 KPI41022.1 - 4.7e-79 266.4 21.6 5.4e-79 266.2 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41022.1 - 4.9e-15 55.3 33.5 1.4e-14 53.8 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S7 PF00177.21 KPI41023.1 - 6.4e-36 123.2 2.1 8.1e-36 122.9 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e BTB PF00651.31 KPI41025.1 - 8.8e-08 32.4 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Tma16 PF11176.8 KPI41026.1 - 0.12 12.2 2.0 0.2 11.5 2.0 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Pirin PF02678.16 KPI41027.1 - 0.0003 20.7 0.1 0.00077 19.4 0.1 1.7 1 0 0 1 1 1 1 Pirin ATG22 PF11700.8 KPI41028.1 - 7.3e-116 387.6 18.6 7.4e-102 341.4 15.7 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like CAMSAP_CH PF11971.8 KPI41029.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain NuA4 PF09340.10 KPI41030.1 - 2.9e-20 71.9 0.8 5.5e-20 71.0 0.8 1.7 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Pkinase PF00069.25 KPI41031.1 - 1.2e-50 172.4 0.0 2.7e-50 171.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41031.1 - 2.7e-20 72.8 0.0 1e-19 70.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KPI41031.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EHN PF06441.12 KPI41032.1 - 6.2e-31 107.0 0.0 1.1e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI41032.1 - 2.4e-10 40.5 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI41032.1 - 1.1e-05 26.1 1.4 2.3e-05 25.1 1.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family HA2 PF04408.23 KPI41033.1 - 2e-15 57.0 0.1 2e-15 57.0 0.1 2.4 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPI41033.1 - 1.4e-14 54.3 0.0 5.3e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain adh_short_C2 PF13561.6 KPI41034.1 - 1.2e-48 165.8 0.2 2.1e-48 164.9 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI41034.1 - 5.4e-38 130.4 0.0 8.7e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI41034.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 KR domain DNA_pol_lambd_f PF10391.9 KPI41034.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DASH_Dam1 PF08653.10 KPI41034.1 - 0.21 11.4 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Hemerythrin PF01814.23 KPI41035.1 - 3.7e-09 37.3 0.2 5.3e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1378 PF07125.11 KPI41035.1 - 1.8 8.8 4.1 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Thioredoxin PF00085.20 KPI41036.1 - 2.3e-05 24.3 0.0 4.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPI41036.1 - 0.0017 18.8 0.0 0.0024 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KPI41036.1 - 0.0086 15.5 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KPI41036.1 - 0.066 13.6 0.0 0.33 11.3 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like bZIP_1 PF00170.21 KPI41037.1 - 0.00055 20.0 5.5 0.00089 19.3 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor NAM-associated PF14303.6 KPI41037.1 - 0.014 16.1 0.2 5.9 7.6 0.1 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain PspC PF04024.12 KPI41038.1 - 0.32 10.9 2.2 15 5.5 0.2 2.2 2 0 0 2 2 2 0 PspC domain MFS_1 PF07690.16 KPI41039.1 - 1.3e-32 113.2 25.2 1.9e-32 112.6 25.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_8 PF13621.6 KPI41040.1 - 3e-14 53.3 0.1 4.9e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KPI41040.1 - 3.7e-11 43.5 0.1 9.4e-11 42.1 0.1 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KPI41040.1 - 0.083 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 KPI41040.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF745 PF05335.13 KPI41041.1 - 0.011 15.5 0.3 0.015 15.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BORCS7 PF16088.5 KPI41041.1 - 0.093 13.0 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Spc29 PF17082.5 KPI41041.1 - 0.53 10.1 3.8 1.2 8.9 1.5 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 Mito_carr PF00153.27 KPI41042.1 - 3.3e-46 155.2 7.1 1.8e-15 56.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI41042.1 - 0.0076 15.4 3.9 0.55 9.3 1.7 3.1 1 1 1 2 2 2 2 Gammaproteobacterial serine protease PsbX PF06596.11 KPI41042.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Dus PF01207.17 KPI41043.1 - 1.7e-39 135.7 0.0 1.7e-27 96.4 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KPI41043.1 - 0.0029 17.4 3.3 0.0029 17.4 3.3 3.5 4 0 0 4 4 4 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KPI41043.1 - 0.0054 16.8 10.9 0.053 13.6 2.2 3.4 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KPI41043.1 - 0.028 14.3 5.8 0.054 13.4 0.5 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KPI41043.1 - 2.3 8.9 8.2 2.6 8.8 3.0 2.5 1 1 1 2 2 2 0 Torus domain Lyase_1 PF00206.20 KPI41045.1 - 2.1e-38 132.5 0.1 8.1e-38 130.6 0.0 1.7 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 KPI41045.1 - 2.6e-22 79.2 1.0 4.8e-22 78.3 0.2 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Acyl-CoA_dh_1 PF00441.24 KPI41046.1 - 6.8e-22 78.3 0.4 1.3e-21 77.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI41046.1 - 3.2e-14 53.6 0.0 6.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI41046.1 - 9.2e-09 35.4 0.0 2.4e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI41046.1 - 6.3e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 KPI41047.1 - 1.4e-20 73.6 0.0 1.7e-17 63.5 0.0 3.3 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KPI41047.1 - 8.1e-14 51.4 0.0 4.6e-13 48.9 0.0 2.2 2 1 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 KPI41047.1 - 5e-13 49.1 0.0 2.1e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KPI41047.1 - 6.7e-12 45.5 0.7 5.4e-11 42.5 0.3 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41047.1 - 9.2e-08 32.2 0.5 0.00054 19.9 0.0 3.9 3 1 1 4 4 4 1 KR domain 3Beta_HSD PF01073.19 KPI41047.1 - 0.00019 20.5 0.0 0.00061 18.9 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPI41047.1 - 0.00077 18.7 0.0 0.0018 17.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPI41047.1 - 0.0015 18.0 0.2 0.0061 16.0 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase UL41A PF17591.2 KPI41048.1 - 0.22 11.7 2.9 0.71 10.0 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus UL41A Dscam_C PF12355.8 KPI41048.1 - 0.45 11.5 9.1 0.2 12.6 1.0 2.7 2 1 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal HTH_30 PF13556.6 KPI41049.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain TBK1_ULD PF18396.1 KPI41049.1 - 0.15 12.0 0.1 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Imm51 PF15595.6 KPI41050.1 - 0.0064 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Immunity protein 51 AIM5 PF17050.5 KPI41050.1 - 0.06 14.2 0.0 0.26 12.1 0.0 2.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 Adenylsucc_synt PF00709.21 KPI41051.1 - 2.7e-160 533.9 0.0 3.1e-160 533.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MOZ_SAS PF01853.18 KPI41052.1 - 2.4e-56 190.3 0.0 3.7e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KPI41052.1 - 1.4e-13 50.2 0.6 7e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain IF2_N PF04760.15 KPI41052.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF1275 PF06912.11 KPI41053.1 - 9.7e-46 156.1 12.7 1.1e-45 155.9 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fungal_trans_2 PF11951.8 KPI41054.1 - 0.0013 17.6 0.2 0.0043 15.9 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain RPT PF13446.6 KPI41054.1 - 0.071 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein ENTH PF01417.20 KPI41055.1 - 1.4e-44 151.2 0.0 2.2e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KPI41055.1 - 0.00058 18.9 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KPI41055.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF5102 PF17104.5 KPI41055.1 - 0.17 11.9 3.7 0.27 11.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) AAR2 PF05282.11 KPI41056.1 - 5.3e-71 239.9 0.0 3.8e-70 237.1 0.0 1.9 1 1 0 1 1 1 1 AAR2 protein Ndc80_HEC PF03801.13 KPI41057.1 - 9.3e-55 184.5 0.0 1.7e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.21 KPI41057.1 - 0.0055 16.3 19.0 0.0055 16.3 19.0 2.9 2 1 0 2 2 2 2 Intermediate filament protein GNAT_acetyltran PF12746.7 KPI41057.1 - 0.037 13.6 1.6 0.057 13.0 0.2 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase FAM110_N PF14161.6 KPI41057.1 - 0.071 13.3 0.2 15 5.8 0.0 3.0 2 0 0 2 2 2 0 Centrosome-associated N terminus CENP-F_leu_zip PF10473.9 KPI41057.1 - 0.073 13.1 41.3 0.014 15.4 19.6 3.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 KPI41057.1 - 0.093 11.9 30.2 0.017 14.3 13.0 3.1 3 0 0 3 3 3 0 HAP1 N-terminal conserved region bZIP_1 PF00170.21 KPI41057.1 - 0.73 10.0 13.4 12 6.1 2.0 4.4 2 1 1 3 3 3 0 bZIP transcription factor IF-2B PF01008.17 KPI41057.1 - 0.87 8.7 14.3 0.014 14.6 3.7 2.3 2 0 0 2 2 2 0 Initiation factor 2 subunit family TMPIT PF07851.13 KPI41057.1 - 2.1 7.5 20.2 0.84 8.8 5.3 2.7 2 1 0 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 KPI41057.1 - 2.8 8.4 15.6 7.8 7.0 0.6 4.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 KPI41057.1 - 3.8 7.9 28.6 1.8 8.9 4.3 5.1 3 1 0 3 3 3 0 Tup N-terminal DUF948 PF06103.11 KPI41057.1 - 6 7.2 19.3 0.22 11.8 2.2 4.5 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KPI41057.1 - 6.9 7.1 32.0 0.29 11.6 8.5 2.8 2 1 0 2 2 2 0 Fez1 Peptidase_S10 PF00450.22 KPI41059.1 - 5.7e-80 269.8 0.1 7.6e-80 269.4 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ATG27 PF09451.10 KPI41059.1 - 6.6e-79 265.5 0.1 9.6e-79 264.9 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Peptidase_S28 PF05577.12 KPI41060.1 - 5.7e-50 170.4 0.3 1.6e-48 165.6 0.3 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ten1 PF12658.7 KPI41061.1 - 1.9e-17 63.4 0.0 2.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Transp_cyt_pur PF02133.15 KPI41062.1 - 1.8e-97 326.9 42.5 2.3e-97 326.6 42.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_3_C PF01915.22 KPI41063.1 - 9.7e-43 146.5 0.0 1.4e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI41063.1 - 3.1e-40 138.5 0.0 6.8e-40 137.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI41063.1 - 6.6e-16 58.2 0.1 1.6e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPI41063.1 - 1.1e-06 28.5 0.6 2.1e-06 27.6 0.6 1.4 1 0 0 1 1 1 1 PA14 domain Rop PF01815.16 KPI41063.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Rop protein DnaJ_C PF01556.18 KPI41065.1 - 2e-37 128.5 0.0 2.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPI41065.1 - 3.1e-10 40.0 1.3 3.1e-10 40.0 1.3 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPI41065.1 - 1.4e-09 38.1 22.4 2.8e-09 37.2 22.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KPI41065.1 - 1.1 9.3 8.0 12 5.9 8.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 KPI41065.1 - 6.3 6.6 11.6 29 4.5 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain iPGM_N PF06415.13 KPI41066.1 - 1.6e-77 259.8 0.1 2.5e-77 259.2 0.1 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KPI41066.1 - 5.8e-70 235.5 0.0 6.9e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KPI41066.1 - 3e-06 26.9 0.0 7.6e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KPI41066.1 - 5e-05 23.1 0.0 8.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KPI41066.1 - 0.0061 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Alkaline phosphatase Ndc1_Nup PF09531.10 KPI41067.1 - 5.5e-05 22.1 7.0 7.4e-05 21.6 7.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KPI41067.1 - 0.00014 20.8 7.5 0.00019 20.4 7.5 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF2207 PF09972.9 KPI41067.1 - 0.004 16.0 0.0 0.0056 15.5 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) VSP PF03302.13 KPI41067.1 - 0.0046 15.9 6.6 0.0065 15.4 6.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein AJAP1_PANP_C PF15298.6 KPI41067.1 - 0.016 15.5 13.3 0.027 14.7 13.3 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus SPX PF03105.19 KPI41067.1 - 0.031 14.2 7.7 0.04 13.8 7.7 1.2 1 0 0 1 1 1 0 SPX domain RIFIN PF02009.16 KPI41067.1 - 0.034 14.0 7.2 0.048 13.5 7.2 1.2 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 KPI41067.1 - 0.059 12.8 2.8 0.075 12.4 2.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Stevor PF17410.2 KPI41067.1 - 0.13 11.7 0.8 0.2 11.2 0.8 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Podoplanin PF05808.11 KPI41067.1 - 0.46 10.6 22.7 1.3 9.1 22.7 1.7 1 1 0 1 1 1 0 Podoplanin DUF4614 PF15391.6 KPI41067.1 - 0.91 9.5 18.6 1.6 8.7 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) MGC-24 PF05283.11 KPI41067.1 - 1.1 9.7 23.1 3.5 8.1 23.1 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SOG2 PF10428.9 KPI41067.1 - 1.5 7.9 17.0 2.1 7.4 17.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 KPI41067.1 - 1.7 7.3 9.3 2.3 6.9 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.12 KPI41067.1 - 1.8 7.1 21.1 2.5 6.6 21.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SKG6 PF08693.10 KPI41067.1 - 2 7.9 8.1 7.7 6.0 8.1 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GREB1 PF15782.5 KPI41067.1 - 2.1 5.3 8.0 2.6 5.1 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 KPI41067.1 - 3 5.8 9.6 3.7 5.6 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 KPI41067.1 - 3.1 6.7 14.7 3.9 6.3 14.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Strabismus PF06638.11 KPI41067.1 - 3.1 6.3 5.3 4.5 5.8 5.3 1.2 1 0 0 1 1 1 0 Strabismus protein TMEM154 PF15102.6 KPI41067.1 - 3.3 7.6 14.8 1.4e+02 2.3 14.8 2.3 1 1 0 1 1 1 0 TMEM154 protein family SAGA-Tad1 PF12767.7 KPI41067.1 - 4.3 7.0 8.4 6.2 6.5 8.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3827 PF12877.7 KPI41067.1 - 4.9 5.4 9.5 6.7 4.9 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ecl1 PF12855.7 KPI41067.1 - 6.6 7.9 26.8 14 6.8 26.8 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Macoilin PF09726.9 KPI41067.1 - 7.7 4.9 13.0 10 4.5 13.0 1.1 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 KPI41067.1 - 9.3 5.9 21.7 14 5.3 21.7 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Fungal_trans PF04082.18 KPI41068.1 - 3.4e-08 32.9 0.1 5.7e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.7 KPI41069.1 - 0.066 13.1 1.4 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like DUF3464 PF11947.8 KPI41069.1 - 0.16 11.7 0.4 0.3 10.8 0.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Na_Ca_ex PF01699.24 KPI41070.1 - 5.5e-40 136.8 39.0 5.4e-22 78.4 17.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF966 PF06136.13 KPI41070.1 - 0.68 9.6 3.2 0.96 9.1 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Sld5 PF05916.11 KPI41071.1 - 3.5e-32 111.1 0.0 5.9e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Sugar_tr PF00083.24 KPI41072.1 - 2.7e-97 326.5 21.1 3.2e-97 326.2 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41072.1 - 5.1e-23 81.6 44.8 5.6e-20 71.6 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PPR_2 PF13041.6 KPI41073.1 - 3.1e-20 72.1 0.0 2.6e-13 49.9 0.0 3.1 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 KPI41073.1 - 9.8e-06 25.6 0.0 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 KPI41073.1 - 0.00086 19.4 7.0 0.0035 17.5 0.0 4.1 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KPI41073.1 - 0.01 15.2 0.1 5.4 6.3 0.0 2.6 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KPI41073.1 - 0.014 15.1 0.0 8.2 6.2 0.0 4.2 4 0 0 4 4 4 0 PPR repeat SAP18 PF06487.12 KPI41074.1 - 3.3e-40 137.5 0.0 3.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pro_isomerase PF00160.21 KPI41075.1 - 1.3e-43 149.0 0.3 1.7e-43 148.6 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YCII PF03795.14 KPI41077.1 - 4.1e-09 36.7 0.0 4.5e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain ATP-synt_ab_Xtn PF16886.5 KPI41077.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension BLOC1_2 PF10046.9 KPI41078.1 - 0.031 14.6 2.6 0.18 12.1 0.4 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1937 PF09152.10 KPI41078.1 - 0.087 13.6 0.0 0.22 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) Arfaptin PF06456.13 KPI41078.1 - 0.24 10.9 3.7 0.26 10.8 0.1 2.6 3 0 0 3 3 3 0 Arfaptin-like domain DUF2390 PF09523.10 KPI41078.1 - 1 9.7 6.5 0.21 12.0 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) FRB_dom PF08771.11 KPI41078.1 - 1.8 9.0 4.4 15 6.0 0.3 3.6 3 1 0 3 3 3 0 FKBP12-rapamycin binding domain HR1 PF02185.16 KPI41078.1 - 2.7 8.2 5.9 1.7 8.8 1.4 2.8 3 0 0 3 3 3 0 Hr1 repeat PilJ PF13675.6 KPI41078.1 - 3.5 7.7 11.1 1.5 8.8 0.7 3.5 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pex19 PF04614.12 KPI41078.1 - 4.1 7.1 7.7 0.97 9.2 3.5 1.9 2 0 0 2 2 2 0 Pex19 protein family SRP19 PF01922.17 KPI41080.1 - 1.1e-24 87.2 0.0 1.6e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Paf67 PF10255.9 KPI41082.1 - 5.1e-140 467.0 0.0 3e-138 461.2 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 UDPGP PF01704.18 KPI41083.1 - 1.6e-56 191.8 0.0 2e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KPI41083.1 - 0.1 12.9 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain Amidase PF01425.21 KPI41085.1 - 1.6e-94 317.5 0.0 1.3e-93 314.4 0.0 2.1 1 1 0 1 1 1 1 Amidase Beta-lactamase PF00144.24 KPI41086.1 - 1.9e-36 126.0 0.1 3e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase PLDc_2 PF13091.6 KPI41087.1 - 1.2e-18 67.2 0.0 7.6e-10 38.8 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KPI41087.1 - 1.7e-06 28.0 0.0 0.004 17.3 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Fungal_trans PF04082.18 KPI41088.1 - 1.3e-09 37.4 0.3 2.2e-09 36.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KPI41089.1 - 3.5e-29 101.8 0.1 4.2e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_D_N PF18018.1 KPI41090.1 - 0.65 10.1 4.1 18 5.5 0.9 2.4 1 1 1 2 2 2 0 DNA polymerase delta subunit OB-fold domain TRI12 PF06609.13 KPI41091.1 - 1.4e-61 208.7 21.1 1.7e-61 208.4 21.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI41091.1 - 1.5e-24 86.6 55.9 2.2e-24 86.1 45.9 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41091.1 - 6.4e-15 54.9 5.5 6.4e-15 54.9 5.5 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter PA PF02225.22 KPI41091.1 - 0.056 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 PA domain DUF4131 PF13567.6 KPI41091.1 - 6.2 6.4 19.3 1.4 8.5 0.0 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) Aminotran_5 PF00266.19 KPI41092.1 - 1.2e-08 34.3 0.0 3.9e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 KPI41092.1 - 0.0052 15.5 0.0 0.008 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Aconitase PF00330.20 KPI41092.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Methyltransf_16 PF10294.9 KPI41094.1 - 3.5e-20 72.4 0.0 3.7e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KPI41094.1 - 9.3e-06 25.6 0.0 2.5e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KPI41094.1 - 7.4e-05 22.4 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KPI41094.1 - 0.00031 21.4 0.1 0.0025 18.5 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain PrmA PF06325.13 KPI41094.1 - 0.00034 20.1 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KPI41094.1 - 0.0014 18.4 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KPI41094.1 - 0.0014 19.3 0.3 0.0072 17.0 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Met_10 PF02475.16 KPI41094.1 - 0.055 13.2 0.0 0.21 11.3 0.0 1.8 1 1 1 2 2 2 0 Met-10+ like-protein PCMT PF01135.19 KPI41094.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KPI41094.1 - 0.092 12.5 0.1 0.21 11.4 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain PC4 PF02229.16 KPI41095.1 - 0.047 13.3 0.2 0.089 12.4 0.2 1.5 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Acetyltransf_10 PF13673.7 KPI41096.1 - 2.4e-05 24.3 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI41096.1 - 5.3e-05 23.6 0.0 7.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI41096.1 - 0.0015 18.8 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPI41096.1 - 0.033 14.2 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF997 PF06196.12 KPI41097.1 - 0.0029 17.6 1.4 0.99 9.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF997) zf-MYND PF01753.18 KPI41098.1 - 4.7e-12 45.8 8.7 7.5e-12 45.1 8.7 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KPI41098.1 - 2 8.8 10.3 6.7 7.1 10.3 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PRP21_like_P PF12230.8 KPI41099.1 - 0.003 17.5 1.2 0.003 17.5 1.2 2.6 2 1 1 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein RFX_DNA_binding PF02257.15 KPI41099.1 - 0.22 12.2 0.0 0.44 11.2 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DnaJ PF00226.31 KPI41100.1 - 7.9e-17 61.1 1.4 1.6e-16 60.2 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain Ima1_N PF09779.9 KPI41100.1 - 0.091 13.6 1.2 0.19 12.6 0.0 2.0 2 1 0 2 2 2 0 Ima1 N-terminal domain SYCE1 PF15233.6 KPI41100.1 - 0.13 12.3 1.6 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 zf-C2H2_aberr PF17017.5 KPI41101.1 - 0.00012 22.3 1.2 0.017 15.3 0.0 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KPI41101.1 - 0.00043 20.6 12.5 0.096 13.2 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI41101.1 - 0.0022 18.7 13.5 0.079 13.8 1.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4719 PF15843.5 KPI41101.1 - 0.0077 16.4 0.7 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4719) zf-H2C2_2 PF13465.6 KPI41101.1 - 0.032 14.7 0.8 0.032 14.7 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPI41101.1 - 0.044 14.1 4.2 1.1 9.7 1.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI41101.1 - 5.3 7.6 5.7 1.2 9.7 1.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Radical_SAM PF04055.21 KPI41102.1 - 2.1e-05 24.9 4.0 0.0021 18.4 0.0 2.3 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KPI41102.1 - 0.002 18.4 3.6 0.15 12.4 0.0 2.5 1 1 1 2 2 2 2 4Fe-4S single cluster domain Ish1 PF10281.9 KPI41102.1 - 0.13 12.6 0.8 0.83 10.0 0.1 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Fer4_14 PF13394.6 KPI41102.1 - 0.54 10.4 4.7 2.8 8.1 0.0 2.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain PHD PF00628.29 KPI41103.1 - 0.0003 20.6 5.4 0.0006 19.7 5.4 1.5 1 0 0 1 1 1 1 PHD-finger VEFS-Box PF09733.9 KPI41103.1 - 0.0018 18.1 1.3 0.0041 16.9 1.3 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Gp49 PF05973.14 KPI41103.1 - 0.0079 16.3 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 1 Phage derived protein Gp49-like (DUF891) Prok-RING_1 PF14446.6 KPI41103.1 - 0.064 13.2 2.7 0.24 11.4 2.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KPI41103.1 - 6.4 7.2 7.3 2.3 8.6 4.0 2.1 2 0 0 2 2 2 0 Ring finger domain Methyltransf_11 PF08241.12 KPI41104.1 - 3.3e-13 50.1 0.0 7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI41104.1 - 2.6e-12 47.3 0.1 9.2e-12 45.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI41104.1 - 1.9e-11 44.6 0.0 1.6e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI41104.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI41104.1 - 2.6e-06 27.4 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI41104.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KPI41104.1 - 0.0036 16.9 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain VPS9 PF02204.18 KPI41105.1 - 4.1e-27 94.4 0.0 8.1e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain AMP-binding PF00501.28 KPI41106.1 - 3.2e-85 286.3 0.0 4.1e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI41106.1 - 1.5e-13 51.5 1.0 4.6e-13 50.0 1.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KPI41106.1 - 0.0015 17.4 0.0 0.0053 15.7 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KPI41106.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain Aldo_ket_red PF00248.21 KPI41107.1 - 2.6e-48 164.7 0.0 3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KPI41108.1 - 2e-21 76.3 26.6 4.4e-18 65.3 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KPI41109.1 - 4.8e-29 101.4 39.8 4.8e-29 101.4 39.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41109.1 - 0.0098 14.8 33.3 0.085 11.7 12.0 3.6 3 2 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI41110.1 - 4.6e-36 124.5 52.8 3e-32 111.9 39.9 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily adh_short PF00106.25 KPI41111.1 - 1.4e-32 112.7 0.0 1.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41111.1 - 1.1e-27 97.2 0.0 1.3e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI41111.1 - 0.00036 20.1 0.1 0.0032 17.0 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KPI41111.1 - 0.00042 20.0 0.6 0.00099 18.7 0.5 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KPI41111.1 - 0.0024 17.8 0.2 0.0057 16.6 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Ribosomal_L13 PF00572.18 KPI41112.1 - 5.2e-11 42.9 0.0 7.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S11 PF00411.19 KPI41113.1 - 2.1e-46 156.9 1.4 2.6e-46 156.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KPI41113.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 KPI41113.1 - 0.1 11.9 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Pex14_N PF04695.13 KPI41114.1 - 5e-29 102.0 7.0 5e-29 102.0 7.0 3.5 3 1 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BicD PF09730.9 KPI41114.1 - 0.00094 17.7 0.0 0.0011 17.5 0.0 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D zf-C4H2 PF10146.9 KPI41114.1 - 0.0014 18.9 4.9 0.0014 18.9 4.9 1.8 2 1 0 2 2 2 1 Zinc finger-containing protein HBM PF16591.5 KPI41114.1 - 0.015 14.8 1.1 0.028 13.9 1.1 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF1043 PF06295.12 KPI41114.1 - 0.015 15.3 1.8 0.015 15.3 1.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Mei5 PF10376.9 KPI41114.1 - 0.057 13.3 4.0 2 8.2 0.8 2.4 1 1 1 2 2 2 0 Double-strand recombination repair protein FAM76 PF16046.5 KPI41114.1 - 0.067 12.5 3.2 0.12 11.7 3.2 1.3 1 0 0 1 1 1 0 FAM76 protein XhlA PF10779.9 KPI41114.1 - 0.068 13.4 9.2 2.2 8.5 2.0 2.7 1 1 2 3 3 3 0 Haemolysin XhlA Prominin PF05478.11 KPI41114.1 - 0.078 10.9 0.7 0.1 10.5 0.7 1.1 1 0 0 1 1 1 0 Prominin Tup_N PF08581.10 KPI41114.1 - 0.093 13.1 1.4 0.2 12.0 1.4 1.6 1 0 0 1 1 1 0 Tup N-terminal HIP1_clath_bdg PF16515.5 KPI41114.1 - 0.1 13.2 0.6 0.1 13.2 0.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4164 PF13747.6 KPI41114.1 - 0.14 12.5 9.5 0.16 12.3 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) SlyX PF04102.12 KPI41114.1 - 0.17 12.5 4.7 0.14 12.8 1.1 2.6 2 1 1 3 3 3 0 SlyX Rsd_AlgQ PF04353.13 KPI41114.1 - 0.22 11.5 1.6 0.26 11.2 0.5 1.6 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ AAA_13 PF13166.6 KPI41114.1 - 0.22 10.1 7.2 0.3 9.7 7.2 1.1 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 KPI41114.1 - 0.22 11.3 3.0 0.37 10.6 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 KPI41114.1 - 0.24 11.4 5.7 5.1 7.1 5.7 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KPI41114.1 - 0.24 11.8 5.1 5.8 7.3 0.3 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG17 PF04108.12 KPI41114.1 - 0.25 10.4 4.8 0.38 9.8 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF148 PF02520.17 KPI41114.1 - 0.28 11.3 4.9 0.38 10.9 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 FlgN PF05130.12 KPI41114.1 - 0.33 11.5 6.9 0.61 10.6 6.9 1.4 1 0 0 1 1 1 0 FlgN protein DUF812 PF05667.11 KPI41114.1 - 0.41 9.5 6.8 0.73 8.6 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4404 PF14357.6 KPI41114.1 - 0.64 10.7 5.7 0.46 11.2 3.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 KPI41114.1 - 1 8.5 3.3 1.5 8.0 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein PRAS PF15798.5 KPI41114.1 - 1.3 9.7 6.1 4.4 7.9 1.5 2.4 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 OmpH PF03938.14 KPI41114.1 - 2.1 8.7 7.2 0.31 11.4 0.9 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KPI41114.1 - 3.2 7.8 6.1 13 5.9 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KPI41114.1 - 5.8 4.3 13.9 0.44 8.0 9.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spem1 PF15670.5 KPI41115.1 - 2.9 7.4 7.3 0.71 9.4 4.0 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 F-box PF00646.33 KPI41116.1 - 0.0064 16.3 1.3 0.011 15.7 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KPI41116.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like ApbA_C PF08546.11 KPI41117.1 - 1e-25 90.3 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPI41117.1 - 1.1e-15 57.6 0.4 5.2e-14 52.2 0.0 2.3 1 1 1 2 2 2 2 Ketopantoate reductase PanE/ApbA DIOX_N PF14226.6 KPI41118.1 - 3.3e-28 98.8 0.1 5.1e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI41118.1 - 8.4e-22 77.6 0.0 1.5e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2517 PF10725.9 KPI41118.1 - 0.16 11.8 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) F-box PF00646.33 KPI41119.1 - 0.0019 18.1 0.0 0.0066 16.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPI41119.1 - 0.079 12.9 0.2 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 F-box-like HAD_2 PF13419.6 KPI41120.1 - 2.3e-17 63.6 0.0 3.8e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI41120.1 - 2.6e-09 37.7 0.0 3.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI41120.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1349 PF07081.11 KPI41121.1 - 3.3e-32 111.6 0.0 4.2e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PIGA PF08288.12 KPI41122.1 - 3.7e-45 152.4 1.9 1.1e-44 151.0 1.9 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KPI41122.1 - 8.3e-27 94.2 0.3 1.6e-26 93.3 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KPI41122.1 - 2.1e-25 89.2 0.0 3.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPI41122.1 - 4.6e-24 85.4 0.5 8.8e-24 84.4 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPI41122.1 - 2.5e-09 37.8 0.0 7.1e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KPI41122.1 - 4.7e-05 23.4 0.1 0.0002 21.4 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KPI41122.1 - 8.3e-05 22.9 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3568 PF12092.8 KPI41123.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Cupin_2 PF07883.11 KPI41124.1 - 1.2e-08 34.5 0.2 2.2e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Paf1 PF03985.13 KPI41126.1 - 4.3e-36 124.8 1.7 1e-35 123.6 1.7 1.6 1 1 0 1 1 1 1 Paf1 Amidase PF01425.21 KPI41127.1 - 8.4e-76 255.7 0.0 5.3e-75 253.1 0.0 1.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 KPI41128.1 - 1.3e-24 86.9 39.4 1.1e-14 54.2 14.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41128.1 - 4.8e-19 68.5 14.4 8.4e-19 67.8 14.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_1 PF00583.25 KPI41129.1 - 1.1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI41129.1 - 3.3e-05 24.2 0.0 7.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI41129.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPI41129.1 - 0.003 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPI41129.1 - 0.019 15.6 0.0 0.031 15.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI41129.1 - 0.15 12.1 0.0 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI41129.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GET2 PF08690.10 KPI41130.1 - 0.071 12.8 3.4 0.15 11.7 3.4 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 CPSF73-100_C PF11718.8 KPI41131.1 - 2.7e-81 272.3 0.0 3.9e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KPI41131.1 - 9.8e-29 99.9 0.0 2e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KPI41131.1 - 2.4e-18 66.3 0.0 4.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KPI41131.1 - 1.5e-17 64.2 0.4 3e-17 63.3 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KPI41131.1 - 5.5e-11 42.2 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KPI41131.1 - 5.6e-06 26.3 0.6 1.8e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KPI41131.1 - 4.9e-05 22.9 1.2 0.00016 21.3 0.3 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Ribosomal_L28 PF00830.19 KPI41131.1 - 0.031 14.5 0.0 0.096 12.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L28 family adh_short PF00106.25 KPI41132.1 - 5.7e-25 87.9 0.0 5.4e-24 84.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41132.1 - 1.6e-21 76.9 0.0 3.2e-21 76.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KPI41132.1 - 0.011 15.3 0.0 0.029 13.8 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI41132.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 KR domain Methyltransf_25 PF13649.6 KPI41132.1 - 0.15 12.8 0.0 0.33 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.22 KPI41134.1 - 8.7e-30 103.9 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 KPI41134.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of band_7 Fungal_trans PF04082.18 KPI41135.1 - 1.7e-19 69.9 0.0 4.8e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI41135.1 - 0.0001 22.4 10.1 0.00019 21.5 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KPI41137.1 - 8.6e-21 74.3 0.0 1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41137.1 - 5.3e-10 39.3 0.0 6.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Plug_translocon PF10559.9 KPI41137.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 2 0 0 2 2 2 0 Plug domain of Sec61p RTA1 PF04479.13 KPI41138.1 - 7.2e-64 215.2 6.8 9e-64 214.9 6.8 1.1 1 0 0 1 1 1 1 RTA1 like protein OCIA PF07051.11 KPI41138.1 - 0.011 15.8 0.4 0.025 14.6 0.4 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF3611 PF12263.8 KPI41138.1 - 0.084 12.8 6.5 0.64 9.9 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) DUF5367 PF17329.2 KPI41138.1 - 0.44 10.7 0.1 0.44 10.7 0.1 3.3 5 0 0 5 5 5 0 Family of unknown function (DUF5367) DUF3176 PF11374.8 KPI41139.1 - 0.16 12.2 2.6 0.21 11.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) DUF2157 PF09925.9 KPI41139.1 - 1.8 8.4 7.3 0.15 11.9 2.4 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) GWT1 PF06423.12 KPI41140.1 - 3.8e-35 121.2 0.2 3.8e-35 121.2 0.2 2.5 2 1 1 3 3 3 1 GWT1 NNMT_PNMT_TEMT PF01234.17 KPI41140.1 - 0.2 10.8 0.0 0.51 9.5 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF4818 PF16089.5 KPI41140.1 - 0.82 10.1 0.1 0.82 10.1 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4818) Sulfatase PF00884.23 KPI41141.1 - 7.3e-61 206.2 0.7 1.2e-60 205.6 0.7 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KPI41141.1 - 0.00097 19.4 0.8 0.004 17.4 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF1664 PF07889.12 KPI41142.1 - 0.00042 20.3 8.7 0.0093 16.0 1.8 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) DUF4686 PF15742.5 KPI41142.1 - 0.0049 16.1 8.5 0.008 15.4 8.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) MerR-DNA-bind PF09278.11 KPI41142.1 - 0.095 13.2 5.1 1.1 9.8 0.6 2.9 2 0 0 2 2 2 0 MerR, DNA binding FH2 PF02181.23 KPI41142.1 - 0.11 11.6 1.6 0.2 10.7 1.6 1.5 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF4795 PF16043.5 KPI41142.1 - 0.21 11.2 7.6 1.6 8.3 7.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4618 PF15397.6 KPI41142.1 - 0.23 10.8 7.0 8.6 5.7 0.3 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4618) Snapin_Pallidin PF14712.6 KPI41142.1 - 0.25 11.8 12.9 0.084 13.3 3.1 3.8 2 1 2 4 4 4 0 Snapin/Pallidin DASH_Hsk3 PF08227.11 KPI41142.1 - 0.29 11.5 7.1 4.6 7.7 1.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF3584 PF12128.8 KPI41142.1 - 0.37 8.2 8.6 0.58 7.6 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 KPI41142.1 - 0.4 10.7 12.9 0.079 13.0 6.0 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein MitMem_reg PF13012.6 KPI41142.1 - 0.44 11.0 3.6 4.6 7.7 2.2 2.9 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function CLZ PF16526.5 KPI41142.1 - 0.54 10.7 4.7 3 8.2 0.3 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 KPI41142.1 - 0.56 10.0 4.6 1.7 8.4 0.7 3.0 3 0 0 3 3 3 0 Septum formation initiator ZapB PF06005.12 KPI41142.1 - 0.66 10.4 3.6 17 6.0 0.6 2.6 2 0 0 2 2 2 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 KPI41142.1 - 0.99 9.4 7.8 1.6 8.8 2.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KPI41142.1 - 1.2 8.5 7.3 0.23 10.8 3.5 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 KPI41142.1 - 2.5 8.4 6.8 4.1 7.7 3.2 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 Lebercilin PF15619.6 KPI41142.1 - 2.6 7.7 7.5 7.7 6.1 7.5 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Lzipper-MIP1 PF14389.6 KPI41142.1 - 3.5 8.0 6.5 3.2 8.1 2.8 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Jnk-SapK_ap_N PF09744.9 KPI41142.1 - 4.4 7.5 8.2 12 6.1 5.5 2.8 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIVA PF05103.13 KPI41142.1 - 5.8 7.0 5.9 19 5.3 5.9 2.0 1 1 0 1 1 1 0 DivIVA protein Spc7 PF08317.11 KPI41142.1 - 6.7 5.5 10.7 3.4 6.5 5.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Fe-S_biosyn PF01521.20 KPI41143.1 - 5.8e-10 39.4 0.0 2.5e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Mg_trans_NIPA PF05653.14 KPI41144.1 - 7.9e-100 333.8 10.7 9.5e-100 333.5 10.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KPI41144.1 - 6.9e-05 23.0 31.5 0.00021 21.5 7.2 3.5 3 1 0 3 3 3 3 EamA-like transporter family Acyl_transf_3 PF01757.22 KPI41144.1 - 6.9 5.6 22.3 1.2 8.2 11.4 2.3 1 1 1 2 2 2 0 Acyltransferase family FMO-like PF00743.19 KPI41145.1 - 2.1e-21 76.0 0.2 2.6e-18 65.7 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI41145.1 - 6.5e-12 45.5 0.0 1.6e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI41145.1 - 8.2e-07 28.5 0.1 0.0023 17.1 0.0 3.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI41145.1 - 2.5e-05 24.3 0.0 0.00058 19.9 0.0 2.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI41145.1 - 0.00021 20.7 0.0 0.0065 15.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI41145.1 - 0.0067 16.1 0.0 0.12 11.9 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KPI41145.1 - 0.15 12.1 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FlgM PF04316.13 KPI41146.1 - 0.56 10.6 3.1 2.9 8.3 3.1 2.3 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM Ribosomal_S24e PF01282.19 KPI41147.1 - 2.7e-34 117.0 0.3 5.3e-34 116.0 0.1 1.6 1 1 1 2 2 2 1 Ribosomal protein S24e NAP PF00956.18 KPI41148.1 - 2.7e-18 66.1 0.4 3.8e-17 62.3 0.3 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Methyltr_RsmB-F PF01189.17 KPI41149.1 - 2.2e-16 60.1 0.0 3.3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Trypan_PARP PF05887.11 KPI41149.1 - 0.12 12.3 2.4 10 6.1 2.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Transferase PF02458.15 KPI41150.1 - 1.9e-09 36.7 0.0 5.7e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Transferase family DUF4185 PF13810.6 KPI41151.1 - 4.3e-14 52.5 1.2 2.1e-13 50.2 1.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) SKG6 PF08693.10 KPI41152.1 - 1.2e-08 34.2 0.3 2.7e-08 33.1 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KPI41152.1 - 0.00013 22.1 0.1 0.00027 21.1 0.1 1.5 1 0 0 1 1 1 1 Podoplanin DUF1180 PF06679.12 KPI41152.1 - 0.00058 20.3 0.5 0.0014 19.1 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Alpha_GJ PF03229.13 KPI41152.1 - 0.0016 19.0 6.8 0.0031 18.0 6.8 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J Rax2 PF12768.7 KPI41152.1 - 0.0075 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity BatD PF13584.6 KPI41152.1 - 0.05 12.4 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Gram_pos_anchor PF00746.21 KPI41152.1 - 0.43 10.6 2.2 1 9.3 2.2 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif IPTL-CTERM PF18203.1 KPI41152.1 - 1.5 8.8 6.4 3.2 7.8 6.4 1.6 1 0 0 1 1 1 0 IPTL-CTERM motif CcmD PF04995.14 KPI41152.1 - 2.6 8.2 4.8 0.77 9.9 2.0 1.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Pex2_Pex12 PF04757.14 KPI41153.1 - 9.9e-34 116.9 6.5 1.4e-33 116.4 6.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KPI41153.1 - 0.014 15.5 4.7 0.032 14.4 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Exop_C PF18559.1 KPI41153.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Galactose-binding domain-like Zn_clus PF00172.18 KPI41154.1 - 3.5e-09 36.6 9.3 7e-09 35.7 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 KPI41155.1 - 1.1e-34 119.9 0.0 2e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KPI41155.1 - 6.3e-14 52.3 10.3 1.1e-13 51.5 10.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KPI41155.1 - 2e-05 24.1 0.2 0.00029 20.3 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KPI41155.1 - 0.0045 16.8 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain FAM176 PF14851.6 KPI41155.1 - 0.0087 15.7 4.5 0.027 14.1 0.0 2.8 3 0 0 3 3 2 1 FAM176 family RsgA_GTPase PF03193.16 KPI41155.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KPI41155.1 - 0.012 15.9 0.1 0.048 13.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KPI41155.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 KPI41155.1 - 0.015 15.8 0.3 0.029 14.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPI41155.1 - 0.02 14.6 0.1 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KPI41155.1 - 0.058 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KPI41155.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Aminotran_1_2 PF00155.21 KPI41156.1 - 1.5e-19 70.4 0.0 1.8e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KPI41156.1 - 0.052 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DNA_pol_A_exo1 PF01612.20 KPI41157.1 - 2.6e-27 95.7 0.3 5.3e-19 68.6 0.0 2.4 1 1 1 2 2 2 2 3'-5' exonuclease PMC2NT PF08066.12 KPI41157.1 - 1.3e-26 93.1 0.4 3.6e-26 91.7 0.4 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KPI41157.1 - 7.3e-12 45.1 0.0 2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 HRDC domain G-patch PF01585.23 KPI41158.1 - 5.8e-12 45.3 2.5 1.6e-11 43.9 2.5 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KPI41158.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase PF01425.21 KPI41159.1 - 6.9e-66 223.1 0.0 1.3e-65 222.1 0.0 1.4 1 1 0 1 1 1 1 Amidase Isochorismatase PF00857.20 KPI41159.1 - 5.5e-41 140.7 0.0 8.7e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Apolipoprotein PF01442.18 KPI41161.1 - 0.0096 15.8 5.9 0.013 15.4 5.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain V-ATPase_G_2 PF16999.5 KPI41161.1 - 0.011 16.1 14.0 0.011 16.1 14.0 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DMPK_coil PF08826.10 KPI41161.1 - 0.1 12.7 2.3 0.2 11.8 2.3 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like CDPS PF16715.5 KPI41161.1 - 0.23 11.1 2.7 0.29 10.7 2.7 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF5427 PF10310.9 KPI41161.1 - 0.29 10.0 8.7 0.34 9.8 8.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TMP_2 PF06791.13 KPI41161.1 - 0.38 10.4 7.4 0.52 10.0 7.4 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein REF PF05755.12 KPI41161.1 - 0.67 9.7 3.7 0.85 9.4 3.7 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF4407 PF14362.6 KPI41161.1 - 2.5 7.4 10.1 3.1 7.1 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRF PF01765.19 KPI41161.1 - 3.7 7.5 9.7 4.8 7.1 9.7 1.2 1 1 0 1 1 1 0 Ribosome recycling factor OmpH PF03938.14 KPI41161.1 - 5.1 7.4 12.4 8 6.8 12.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3405 PF11885.8 KPI41162.1 - 1.1e-151 506.0 3.6 4.4e-145 484.2 1.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) HisKA_2 PF07568.12 KPI41163.1 - 0.018 15.1 0.1 0.16 12.1 0.0 2.2 1 1 0 2 2 2 0 Histidine kinase ADH_zinc_N_2 PF13602.6 KPI41164.1 - 6.8e-12 46.6 0.0 1.2e-11 45.8 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Acyl_transf_3 PF01757.22 KPI41165.1 - 6.2e-32 111.0 30.7 7.4e-32 110.7 30.7 1.1 1 0 0 1 1 1 1 Acyltransferase family eRF1_1 PF03463.15 KPI41166.1 - 2.6e-47 160.1 0.0 3.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KPI41166.1 - 1.2e-20 74.2 0.0 1.8e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KPI41166.1 - 1.9e-20 73.4 0.0 3.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 DUF695 PF05117.12 KPI41166.1 - 0.049 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF695) Chitin_synth_1 PF01644.17 KPI41167.1 - 1e-77 259.7 0.0 1.5e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KPI41167.1 - 1.9e-26 91.8 0.1 5.1e-26 90.4 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KPI41167.1 - 3.5e-21 75.4 0.4 2.3e-19 69.4 0.0 2.3 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KPI41167.1 - 3.1e-06 27.2 3.3 9.4e-06 25.7 3.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 CUE PF02845.16 KPI41168.1 - 5.1e-08 32.5 0.0 7.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KPI41168.1 - 0.0058 16.2 11.5 0.012 15.2 11.5 1.5 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) Fungal_trans_2 PF11951.8 KPI41169.1 - 0.00012 21.0 0.1 0.00013 20.9 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMPK1_CBM PF16561.5 KPI41170.1 - 3.5e-20 72.0 0.7 6.7e-20 71.1 0.7 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF2613 PF11021.8 KPI41170.1 - 0.0026 17.8 0.3 0.0026 17.8 0.3 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2613) BTB PF00651.31 KPI41171.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Metallopep PF12044.8 KPI41172.1 - 8.3e-163 541.9 0.0 1e-162 541.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KPI41172.1 - 0.0085 16.0 0.1 0.17 11.8 0.0 2.4 1 1 1 2 2 2 2 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KPI41172.1 - 0.025 14.8 0.2 0.052 13.7 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KPI41172.1 - 0.1 13.1 0.2 0.23 12.0 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KPI41172.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DPBB_1 PF03330.18 KPI41173.1 - 0.03 14.6 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 Lytic transglycolase DUF3659 PF12396.8 KPI41174.1 - 1.3e-269 870.5 180.5 1.5e-22 79.3 2.7 13.7 13 0 0 13 13 13 13 Protein of unknown function (DUF3659) DUF883 PF05957.13 KPI41174.1 - 0.00028 21.4 46.5 0.46 11.1 1.1 8.2 6 2 0 6 6 6 2 Bacterial protein of unknown function (DUF883) NPHI_C PF08469.10 KPI41174.1 - 0.00091 19.2 5.4 25 4.8 0.0 7.8 7 2 2 9 9 9 1 Nucleoside triphosphatase I C-terminal YtxH PF12732.7 KPI41174.1 - 0.0043 17.5 1.9 0.0043 17.5 1.9 9.6 7 2 0 8 8 8 2 YtxH-like protein RPW8 PF05659.11 KPI41174.1 - 4.1 7.1 6.7 0.33 10.6 0.9 2.1 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Apolipoprotein PF01442.18 KPI41174.1 - 6.2 6.6 50.4 0.95 9.3 0.3 6.5 5 3 1 6 6 6 0 Apolipoprotein A1/A4/E domain Synaptobrevin PF00957.21 KPI41175.1 - 1e-14 54.1 0.7 1.6e-14 53.4 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KPI41175.1 - 1.6e-10 40.9 0.1 2.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Homez PF11569.8 KPI41175.1 - 0.052 13.0 0.1 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF16 PF01519.16 KPI41175.1 - 0.09 13.3 1.2 0.14 12.6 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Transket_pyr PF02779.24 KPI41177.1 - 4.3e-48 163.4 0.0 6.6e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPI41177.1 - 1.9e-35 121.4 0.2 4.9e-35 120.1 0.2 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DAGK_cat PF00781.24 KPI41178.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1609 PF07753.11 KPI41178.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Oxysterol_BP PF01237.18 KPI41180.1 - 3.4e-89 299.3 0.1 2.6e-80 270.0 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein CDH-cyt PF16010.5 KPI41181.1 - 2.4e-26 92.5 1.4 4.1e-26 91.8 1.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KPI41181.1 - 1.1e-10 41.8 0.1 2e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KPI41181.1 - 1.4e-07 31.8 8.1 2.2e-07 31.1 8.1 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KPI41181.1 - 0.00023 20.9 1.8 0.00044 20.0 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF5391 PF17369.2 KPI41181.1 - 0.00067 19.7 1.0 0.0013 18.8 1.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5391) PAP1 PF08601.10 KPI41181.1 - 7.5 6.2 13.4 11 5.6 13.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Clr5 PF14420.6 KPI41182.1 - 3e-06 27.4 7.4 7e-06 26.2 7.4 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KPI41182.1 - 0.089 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NIF PF03031.18 KPI41183.1 - 9.8e-26 90.4 0.0 1.8e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NAD_binding_8 PF13450.6 KPI41184.1 - 3.2e-11 43.3 0.0 7.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KPI41184.1 - 6.3e-10 38.1 0.2 1.5e-07 30.3 0.1 2.8 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI41184.1 - 1.9e-06 27.4 0.0 0.0043 16.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI41184.1 - 9e-05 22.2 0.0 0.11 12.1 0.0 3.0 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI41184.1 - 0.00026 21.0 0.0 0.0037 17.3 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPI41184.1 - 0.0013 18.0 0.0 1.1 8.3 0.0 3.5 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI41184.1 - 0.0014 17.9 0.0 0.083 12.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI41184.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KPI41184.1 - 0.091 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Rad9 PF04139.13 KPI41185.1 - 2.7e-50 171.2 0.0 3.3e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KPI41185.1 - 6.1e-05 22.2 0.0 0.00034 19.8 0.0 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 zf-C2H2 PF00096.26 KPI41186.1 - 6e-06 26.4 10.4 0.0039 17.6 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI41186.1 - 0.00024 21.4 3.8 0.00024 21.4 3.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI41186.1 - 0.0011 19.6 10.7 0.064 14.1 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KPI41186.1 - 1.1 9.0 6.0 1.9 8.4 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FAA_hydrolase PF01557.18 KPI41187.1 - 1.5e-43 149.0 0.0 2e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GDP_Man_Dehyd PF16363.5 KPI41188.1 - 5.7e-69 233.1 0.0 7e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI41188.1 - 2.3e-57 194.2 0.0 3.2e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI41188.1 - 2.2e-31 109.1 0.0 1.1e-30 106.7 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KPI41188.1 - 3.5e-23 82.0 0.0 4.9e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPI41188.1 - 9e-20 70.9 0.5 1.9e-18 66.6 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KPI41188.1 - 2.1e-16 59.9 0.0 4.2e-16 58.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KPI41188.1 - 4.5e-06 26.7 0.0 1.2e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KPI41188.1 - 0.0014 18.1 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI41188.1 - 0.048 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 KR domain zf-RING_2 PF13639.6 KPI41189.1 - 8.9e-10 38.8 8.3 1.4e-09 38.1 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KPI41189.1 - 3.2e-07 30.0 2.7 6.2e-07 29.0 2.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KPI41189.1 - 1.5e-06 28.4 6.4 3.2e-06 27.3 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI41189.1 - 1.1e-05 25.4 6.3 2.6e-05 24.2 6.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KPI41189.1 - 2.7e-05 23.9 4.2 4.4e-05 23.2 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI41189.1 - 0.00011 22.0 9.0 0.00018 21.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KPI41189.1 - 0.00013 22.0 3.7 0.00025 21.1 3.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.6 KPI41189.1 - 0.0022 18.0 2.3 0.0043 17.1 2.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPI41189.1 - 0.0022 17.8 2.6 0.0041 16.9 2.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KPI41189.1 - 0.0096 15.8 6.2 0.015 15.2 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI41189.1 - 0.014 15.4 6.9 0.022 14.7 6.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KPI41189.1 - 0.025 14.4 3.8 0.042 13.6 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KPI41189.1 - 0.042 14.0 5.7 0.18 12.0 5.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PCI PF01399.27 KPI41190.1 - 0.00051 20.5 0.0 0.0021 18.6 0.0 2.0 2 0 0 2 2 2 1 PCI domain Lant_dehydr_N PF04738.13 KPI41190.1 - 0.0022 16.2 0.4 0.003 15.7 0.4 1.1 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus SKA2 PF16740.5 KPI41190.1 - 0.1 12.4 2.6 0.23 11.2 2.6 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Lambda_Kil PF06301.11 KPI41190.1 - 0.12 12.0 0.4 0.82 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein Med9 PF07544.13 KPI41190.1 - 0.21 11.7 1.6 0.47 10.6 1.6 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 zf-H2C2_2 PF13465.6 KPI41191.1 - 8.8e-07 29.1 11.4 1.3e-06 28.5 0.9 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI41191.1 - 0.0006 20.4 15.3 0.027 15.3 3.8 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI41191.1 - 0.0017 18.7 12.3 0.018 15.4 5.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KPI41191.1 - 0.0037 17.5 4.1 0.0063 16.8 4.1 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KPI41191.1 - 0.078 13.3 3.1 2.9 8.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.28 KPI41192.1 - 3.8e-29 101.5 0.0 4.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Choline_kinase PF01633.20 KPI41193.1 - 5.3e-55 186.3 0.0 1.9e-54 184.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KPI41193.1 - 6.7e-17 60.9 0.0 1.9e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KPI41193.1 - 0.00028 20.9 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mur_ligase_M PF08245.12 KPI41194.1 - 7.2e-06 26.1 0.1 1.2e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Metal_CEHH PF14455.6 KPI41194.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Predicted metal binding domain Cys_Met_Meta_PP PF01053.20 KPI41195.1 - 3.5e-58 197.0 0.0 1e-57 195.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPI41195.1 - 0.00016 21.0 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI41195.1 - 0.066 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V TINF2_N PF14973.6 KPI41195.1 - 0.084 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Phage_holin_3_1 PF05106.12 KPI41195.1 - 0.11 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF5521 PF17659.1 KPI41196.1 - 0.18 9.6 0.1 0.21 9.4 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) FAM199X PF15814.5 KPI41196.1 - 2.2 7.3 4.5 2.5 7.1 4.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Abhydrolase_3 PF07859.13 KPI41197.1 - 3.8e-51 173.9 0.4 4.9e-51 173.6 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI41197.1 - 9.9e-08 31.3 0.0 4e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KPI41197.1 - 0.0084 15.0 0.0 0.022 13.6 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 KPI41197.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) GIY-YIG PF01541.24 KPI41198.1 - 0.04 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 GIY-YIG catalytic domain ADK_lid PF05191.14 KPI41198.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid PEP-utilisers_N PF05524.13 KPI41198.1 - 0.17 12.1 1.1 0.69 10.1 0.7 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal KxDL PF10241.9 KPI41198.1 - 0.37 11.1 4.0 10 6.5 0.6 3.4 2 0 0 2 2 2 0 Uncharacterized conserved protein zf-C3HC4 PF00097.25 KPI41199.1 - 0.0003 20.6 3.8 0.00061 19.6 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI41199.1 - 0.0022 17.9 4.5 0.0038 17.1 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPI41199.1 - 0.009 15.9 4.7 0.014 15.2 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI41199.1 - 0.049 13.5 6.0 0.11 12.4 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI41199.1 - 0.092 12.6 4.2 0.18 11.7 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KPI41199.1 - 0.17 11.9 6.1 0.37 10.9 6.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KPI41199.1 - 0.27 11.6 5.3 0.53 10.7 5.3 1.4 1 0 0 1 1 1 0 Ring finger domain Pyrophosphatase PF00719.19 KPI41200.1 - 3.3e-38 131.0 0.1 4.5e-38 130.6 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MFS_1 PF07690.16 KPI41201.1 - 2.4e-08 33.3 16.9 2.4e-08 33.3 16.9 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPI41201.1 - 5.7e-07 29.4 3.4 1.7e-06 27.8 2.7 2.2 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 Trp_dioxygenase PF03301.13 KPI41201.1 - 0.054 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase MFS_1_like PF12832.7 KPI41201.1 - 0.23 10.3 9.0 0.047 12.5 3.7 2.1 2 0 0 2 2 2 0 MFS_1 like family GST_C_2 PF13410.6 KPI41202.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COesterase PF00135.28 KPI41203.1 - 2.6e-69 234.4 0.0 3.5e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI41203.1 - 3.5e-05 23.8 0.3 0.00095 19.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI41203.1 - 0.087 12.3 0.6 0.2 11.1 0.6 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KPI41203.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GST_N PF02798.20 KPI41204.1 - 1.4e-13 51.0 0.0 3.2e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI41204.1 - 9.7e-10 38.6 0.0 2.5e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI41204.1 - 7.9e-09 35.8 0.1 1.7e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BTB_2 PF02214.22 KPI41204.1 - 1.4e-06 28.5 0.0 0.0066 16.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain GST_C_3 PF14497.6 KPI41204.1 - 0.00029 21.0 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI41204.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI41204.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PTPRCAP PF15713.5 KPI41204.1 - 1.2 9.4 16.7 4.4 7.6 1.4 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Lin-8 PF03353.15 KPI41204.1 - 5.8 6.4 8.6 1.9 8.0 3.4 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 KPI41204.1 - 8.9 6.3 9.5 0.18 11.8 2.2 1.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.6 KPI41204.1 - 9.4 6.7 11.8 3.4 8.1 2.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PhyH PF05721.13 KPI41205.1 - 1.5e-18 67.8 0.1 2e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KPI41205.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Acyl-CoA_dh_1 PF00441.24 KPI41206.1 - 1.2e-39 136.0 6.7 2.4e-39 134.9 6.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI41206.1 - 5.5e-32 110.8 0.5 1.9e-31 109.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI41206.1 - 1.9e-24 85.7 0.1 5.3e-24 84.3 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI41206.1 - 8.9e-17 61.6 2.5 8.9e-17 61.6 2.5 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KPI41206.1 - 0.0085 15.8 0.9 0.019 14.6 0.1 2.0 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 KPI41206.1 - 0.024 15.2 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal TTL PF03133.15 KPI41207.1 - 6.1e-57 193.0 0.0 9.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KPI41207.1 - 2.8e-35 121.9 0.0 4.7e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KPI41207.1 - 0.00073 18.9 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 YheC/D like ATP-grasp Calici_coat_C PF08435.11 KPI41207.1 - 0.068 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal ATPgrasp_ST PF14397.6 KPI41207.1 - 0.15 11.2 0.0 0.51 9.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 KPI41207.1 - 0.17 11.4 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Prefoldin_2 PF01920.20 KPI41208.1 - 4.6e-23 81.2 4.7 5.6e-23 80.9 4.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4686 PF15742.5 KPI41208.1 - 0.00011 21.4 7.4 0.00014 21.2 7.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Syntaxin-6_N PF09177.11 KPI41208.1 - 0.00071 20.1 6.0 0.091 13.3 5.7 2.2 1 1 0 1 1 1 1 Syntaxin 6, N-terminal Spc24 PF08286.11 KPI41208.1 - 0.0022 18.2 3.7 0.4 11.0 0.7 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 FlxA PF14282.6 KPI41208.1 - 0.0034 17.3 3.8 0.72 9.9 0.7 2.1 2 0 0 2 2 2 2 FlxA-like protein Lzipper-MIP1 PF14389.6 KPI41208.1 - 0.0044 17.3 3.5 0.0044 17.3 3.5 2.0 1 1 1 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 CENP-F_N PF10481.9 KPI41208.1 - 0.0079 15.9 4.4 0.01 15.5 4.4 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain Fib_alpha PF08702.10 KPI41208.1 - 0.014 15.6 3.4 0.022 15.0 3.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LRRFIP PF09738.9 KPI41208.1 - 0.014 14.9 7.3 0.017 14.6 7.3 1.0 1 0 0 1 1 1 0 LRRFIP family DUF2721 PF11026.8 KPI41208.1 - 0.024 14.5 1.3 0.03 14.2 0.4 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2721) Rootletin PF15035.6 KPI41208.1 - 0.031 14.3 4.0 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF2164 PF09932.9 KPI41208.1 - 0.033 14.2 0.2 0.34 11.0 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2164) Csm1_N PF18504.1 KPI41208.1 - 0.054 13.8 9.8 0.57 10.5 0.6 2.6 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2205 PF10224.9 KPI41208.1 - 0.06 13.4 0.3 0.06 13.4 0.3 2.5 2 1 0 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 KPI41208.1 - 0.071 12.9 8.1 1.6 8.6 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.13 KPI41208.1 - 0.13 12.3 8.7 1.9 8.6 8.6 2.3 1 1 0 1 1 1 0 DivIVA protein DUF1465 PF07323.12 KPI41208.1 - 0.13 12.1 3.9 0.086 12.7 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) BST2 PF16716.5 KPI41208.1 - 0.17 12.5 4.7 3 8.5 0.1 2.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 KfrA_N PF11740.8 KPI41208.1 - 0.17 12.5 4.0 0.14 12.9 2.4 1.7 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Prefoldin PF02996.17 KPI41208.1 - 0.31 11.0 7.8 0.72 9.8 1.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 KPI41208.1 - 0.31 10.8 11.4 2.3 8.0 3.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF5320 PF17253.2 KPI41208.1 - 0.41 11.7 1.8 4 8.6 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5320) bZIP_1 PF00170.21 KPI41208.1 - 0.46 10.6 0.3 0.46 10.6 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.19 KPI41208.1 - 0.47 8.3 2.5 0.6 8.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 KPI41208.1 - 0.55 10.3 13.8 0.65 10.0 0.5 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KPI41208.1 - 0.94 10.0 10.1 4.4 7.8 0.4 2.3 2 1 0 2 2 2 0 Cell division protein ZapB Cauli_AT PF03233.13 KPI41208.1 - 1.2 9.0 4.8 2 8.3 2.7 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF4200 PF13863.6 KPI41208.1 - 1.3 9.5 11.2 1 9.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BRE1 PF08647.11 KPI41208.1 - 1.9 8.6 12.0 13 6.0 0.4 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 KPI41208.1 - 1.9 9.2 7.7 2.9 8.6 0.2 2.5 3 0 0 3 3 2 0 SlyX YabA PF06156.13 KPI41208.1 - 2 9.1 6.5 12 6.6 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA UPF0515 PF15135.6 KPI41208.1 - 2.1 7.6 5.1 0.8 9.0 2.3 1.6 1 1 1 2 2 2 0 Uncharacterised protein UPF0515 CLZ PF16526.5 KPI41208.1 - 2.2 8.7 13.1 4.4 7.7 0.6 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4404 PF14357.6 KPI41208.1 - 3 8.5 13.5 0.17 12.5 3.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 KPI41208.1 - 3.1 7.0 5.4 4.2 6.5 2.9 1.8 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 KPI41208.1 - 3.5 8.2 15.0 1.6 9.2 11.4 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region LSPR PF06049.12 KPI41209.1 - 9 6.6 6.6 12 6.2 0.1 3.0 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat 7tm_7 PF08395.12 KPI41210.1 - 0.079 12.1 1.4 0.16 11.2 1.4 1.4 1 0 0 1 1 1 0 7tm Chemosensory receptor bZIP_1 PF00170.21 KPI41210.1 - 0.22 11.6 6.0 0.47 10.6 6.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Penicillinase_R PF03965.16 KPI41211.1 - 0.097 13.0 0.3 0.21 11.9 0.1 1.6 2 0 0 2 2 2 0 Penicillinase repressor CaATP_NAI PF12515.8 KPI41214.1 - 0.014 15.0 0.8 0.036 13.7 0.6 1.7 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Asp PF00026.23 KPI41215.1 - 2.2e-52 178.4 0.6 3.1e-52 178.0 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI41215.1 - 1.2e-07 32.1 8.0 4.6e-05 23.7 0.0 4.0 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KPI41215.1 - 0.0012 18.7 0.1 0.0061 16.4 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Nop14 PF04147.12 KPI41216.1 - 0.29 9.3 10.1 0.39 8.9 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KPI41216.1 - 0.61 8.3 7.4 0.86 7.8 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KPI41216.1 - 0.94 8.8 8.7 1.6 8.1 8.7 1.3 1 0 0 1 1 1 0 SDA1 CFEM PF05730.11 KPI41217.1 - 1.6e-08 34.5 9.2 2.1e-08 34.2 9.2 1.1 1 0 0 1 1 1 1 CFEM domain Aldo_ket_red PF00248.21 KPI41218.1 - 6.3e-41 140.5 0.0 8.1e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DIE2_ALG10 PF04922.12 KPI41219.1 - 1.2e-111 373.8 14.4 1.4e-111 373.6 14.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Nramp PF01566.18 KPI41219.1 - 0.02 13.9 0.2 0.02 13.9 0.2 2.7 3 0 0 3 3 3 0 Natural resistance-associated macrophage protein Chordopox_L2 PF05803.12 KPI41219.1 - 0.066 13.1 0.5 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Syntaxin-6_N PF09177.11 KPI41220.1 - 2.4e-24 85.7 0.4 7.1e-24 84.2 0.1 1.8 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KPI41220.1 - 0.0015 18.4 0.6 0.0036 17.3 0.6 1.7 1 0 0 1 1 1 1 SNARE domain KxDL PF10241.9 KPI41220.1 - 0.044 14.1 2.5 0.82 10.0 0.2 2.8 2 2 1 3 3 3 0 Uncharacterized conserved protein DUF2650 PF10853.8 KPI41220.1 - 0.55 10.0 2.3 0.84 9.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Cnn_1N PF07989.11 KPI41220.1 - 1.6 8.9 4.7 1.8 8.8 0.1 2.5 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF3342 PF11822.8 KPI41222.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) UBA_4 PF14555.6 KPI41222.1 - 0.053 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Pkinase_Tyr PF07714.17 KPI41223.1 - 2.3e-10 40.2 0.0 5.9e-09 35.6 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KPI41223.1 - 5.4e-09 35.8 0.1 6.9e-08 32.2 0.1 2.4 1 1 0 1 1 1 1 Protein kinase domain DUF2985 PF11204.8 KPI41224.1 - 2.5e-23 82.0 1.7 4.8e-23 81.1 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF3605 PF12239.8 KPI41225.1 - 9.6e-55 185.1 4.4 1.2e-54 184.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Sec63 PF02889.16 KPI41227.1 - 2.6e-118 393.8 0.0 4.2e-78 262.1 0.3 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KPI41227.1 - 4.4e-51 173.1 0.1 1.1e-24 87.1 0.1 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KPI41227.1 - 5.7e-22 78.5 0.0 6.3e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI41227.1 - 2.7e-14 53.5 0.1 1e-05 25.8 0.0 4.5 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 KPI41227.1 - 1.4e-08 34.7 0.0 0.0052 16.5 0.2 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KPI41227.1 - 3e-06 27.6 0.4 0.085 13.1 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPI41227.1 - 1.9e-05 25.0 0.3 0.0034 17.7 0.2 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KPI41227.1 - 0.0012 19.3 0.0 1 9.8 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KPI41227.1 - 0.0015 18.7 0.1 0.0056 16.9 0.1 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 KPI41227.1 - 0.014 14.5 0.0 3.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KPI41227.1 - 0.019 14.7 0.1 15 5.3 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.16 KPI41227.1 - 0.022 14.2 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 KPI41227.1 - 0.14 12.5 0.2 19 5.6 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain Neur_chan_memb PF02932.16 KPI41227.1 - 0.34 10.9 1.6 0.64 10.0 1.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BRE1 PF08647.11 KPI41228.1 - 0.01 15.9 11.7 0.01 15.9 11.7 3.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 KPI41228.1 - 0.057 13.7 3.5 0.095 13.0 1.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 KPI41228.1 - 0.4 10.0 33.5 0.18 11.1 1.0 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding PBP_dimer PF03717.15 KPI41228.1 - 1.1 9.6 4.2 0.69 10.2 2.1 1.7 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain Lebercilin PF15619.6 KPI41228.1 - 1.1 8.8 33.7 6.5 6.4 0.4 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KIAA1430 PF13879.6 KPI41228.1 - 6 7.7 11.9 1.9e+02 2.8 11.9 3.1 1 1 0 1 1 1 0 KIAA1430 homologue Bacillus_HBL PF05791.11 KPI41228.1 - 9.3 6.0 8.0 8.5 6.2 0.2 2.5 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) zf-CCHC PF00098.23 KPI41229.1 - 1.1e-46 154.9 64.4 9.2e-09 35.0 2.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KPI41229.1 - 1.1e-09 37.8 43.9 0.21 11.4 1.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KPI41229.1 - 3.7e-06 26.5 43.1 0.013 15.2 0.7 7.1 4 2 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KPI41229.1 - 1e-05 25.4 46.8 0.011 15.7 0.2 6.9 3 2 4 7 7 7 6 Zinc knuckle Caprin-1_C PF12287.8 KPI41229.1 - 0.87 9.7 3.0 1 9.4 3.0 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term ADH_zinc_N PF00107.26 KPI41230.1 - 2.7e-21 75.9 1.8 3.1e-21 75.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI41230.1 - 1.8e-09 37.4 2.5 0.00018 21.4 1.1 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KPI41230.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPI41230.1 - 0.00059 19.2 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KPI41230.1 - 0.0021 18.7 0.0 0.0063 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.18 KPI41230.1 - 0.0096 16.2 0.1 0.016 15.5 0.1 1.5 1 1 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KPI41230.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KPI41230.1 - 0.02 15.6 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PADR1 PF08063.12 KPI41230.1 - 0.053 13.3 0.8 0.19 11.6 0.8 1.9 1 0 0 1 1 1 0 PADR1 (NUC008) domain Adenosine_kin PF04008.14 KPI41232.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenosine specific kinase LRR_4 PF12799.7 KPI41232.1 - 0.29 11.6 1.9 17 6.0 1.4 3.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) PDH PF02153.17 KPI41234.1 - 1.1e-13 50.8 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KPI41234.1 - 8.9e-07 29.4 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KPI41234.1 - 4.4e-05 23.7 0.0 8.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KPI41234.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KPI41234.1 - 0.0096 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KPI41234.1 - 0.036 14.3 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KPI41234.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hydantoinase_B PF02538.14 KPI41235.1 - 1.2e-221 736.6 0.9 1.8e-221 736.1 0.9 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KPI41235.1 - 1.3e-104 349.6 0.3 3.5e-104 348.2 0.3 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KPI41235.1 - 2e-59 200.3 0.6 7.9e-58 195.1 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Creatininase PF02633.14 KPI41235.1 - 0.02 14.4 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Creatinine amidohydrolase FMN_dh PF01070.18 KPI41236.1 - 1e-102 343.8 0.2 6.7e-92 308.2 0.0 2.3 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPI41236.1 - 1.2e-18 67.1 0.0 2.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KPI41236.1 - 0.00016 20.8 0.1 0.0014 17.8 0.0 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KPI41236.1 - 0.00044 19.5 0.0 0.00074 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KPI41236.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DUF3420 PF11900.8 KPI41236.1 - 0.19 11.9 0.8 23 5.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DUF2207 PF09972.9 KPI41237.1 - 0.041 12.6 0.6 0.043 12.6 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LON_substr_bdg PF02190.16 KPI41238.1 - 4.2e-27 95.4 0.0 6.8e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Abhydrolase_1 PF00561.20 KPI41238.1 - 8.3e-16 58.4 0.0 1.2e-14 54.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI41238.1 - 8.7e-16 59.2 0.2 8.7e-16 59.2 0.2 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI41238.1 - 1.9e-12 47.0 0.0 2.8e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 zf-C3HC4_2 PF13923.6 KPI41238.1 - 2.8e-11 43.1 9.3 6.2e-11 42.0 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DSPc PF00782.20 KPI41238.1 - 1.5e-10 41.0 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-RING_2 PF13639.6 KPI41238.1 - 2.1e-07 31.2 8.6 4.8e-07 30.0 8.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KPI41238.1 - 2.3e-07 30.6 8.0 4.7e-07 29.6 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI41238.1 - 2.7e-07 30.5 5.5 3.5e-07 30.1 2.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI41238.1 - 5.3e-07 29.4 8.3 1.1e-06 28.4 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PGAP1 PF07819.13 KPI41238.1 - 1.8e-06 27.9 0.1 3.5e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 PGAP1-like protein zf-RING_5 PF14634.6 KPI41238.1 - 7e-06 25.9 8.2 1.3e-05 25.0 8.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPI41238.1 - 3.2e-05 23.7 7.1 7e-05 22.6 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KPI41238.1 - 3.5e-05 23.9 8.0 7.2e-05 22.9 8.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KPI41238.1 - 0.0003 20.4 4.9 0.00058 19.5 4.9 1.4 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.7 KPI41238.1 - 0.00048 20.4 3.5 0.0015 18.8 3.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Y_phosphatase PF00102.27 KPI41238.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-RING_10 PF16685.5 KPI41238.1 - 0.001 19.1 4.3 0.0018 18.4 4.3 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 Lipase_3 PF01764.25 KPI41238.1 - 0.0019 18.1 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PTPlike_phytase PF14566.6 KPI41238.1 - 0.0031 17.6 0.0 0.0063 16.7 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate PAF-AH_p_II PF03403.13 KPI41238.1 - 0.0057 15.2 0.7 0.39 9.2 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II zf-RING_4 PF14570.6 KPI41238.1 - 0.011 15.5 6.5 0.032 14.0 6.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ser_hydrolase PF06821.13 KPI41238.1 - 0.013 15.3 0.1 0.039 13.8 0.1 1.7 1 0 0 1 1 1 0 Serine hydrolase U-box PF04564.15 KPI41238.1 - 0.025 14.8 0.0 0.09 13.0 0.0 2.0 1 0 0 1 1 1 0 U-box domain Abhydrolase_8 PF06259.12 KPI41238.1 - 0.038 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 KPI41238.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KPI41238.1 - 0.1 12.7 0.8 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Thioesterase domain BAAT_C PF08840.11 KPI41238.1 - 0.15 12.0 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 KPI41238.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase zf-Nse PF11789.8 KPI41238.1 - 0.21 11.5 3.5 0.45 10.4 3.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 KPI41238.1 - 0.53 10.4 4.2 1.2 9.2 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CXCL17 PF15211.6 KPI41238.1 - 0.73 10.6 3.2 1.5 9.6 3.2 1.4 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 DZR PF12773.7 KPI41238.1 - 1 9.4 3.6 2.5 8.2 3.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 KPI41238.1 - 1.2 9.1 3.9 2.8 7.9 3.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein F-box-like PF12937.7 KPI41239.1 - 0.00047 20.0 0.1 0.0058 16.5 0.0 2.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KPI41239.1 - 3.1 8.3 18.0 29 5.3 0.1 6.7 4 2 4 8 8 8 0 Leucine Rich repeats (2 copies) Hexokinase_2 PF03727.16 KPI41241.1 - 1.9e-33 115.9 0.0 3.1e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KPI41241.1 - 6.5e-25 88.2 0.0 3.6e-23 82.5 0.0 2.2 1 1 1 2 2 2 2 Hexokinase HSP70 PF00012.20 KPI41242.1 - 5.2e-218 725.1 3.8 5.9e-218 724.9 3.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPI41242.1 - 5.5e-16 58.3 0.0 8.6e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 KPI41242.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KPI41242.1 - 0.015 14.5 0.1 0.033 13.4 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Oxysterol_BP PF01237.18 KPI41243.1 - 7.2e-134 446.3 0.0 4.5e-133 443.7 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 KPI41243.1 - 2.2e-17 62.9 0.2 3.8e-11 43.0 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI41243.1 - 1.6e-11 44.6 0.0 2.7e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KPI41243.1 - 7.4e-11 42.0 0.1 0.0019 18.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 KPI41243.1 - 1.6e-10 41.4 0.5 4.3e-10 40.0 0.5 1.8 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KPI41243.1 - 3.1e-10 39.4 0.0 0.011 16.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KPI41243.1 - 1.6e-08 34.9 0.0 0.0027 18.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KPI41243.1 - 4.7e-06 26.8 0.9 1.2e-05 25.5 0.9 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KPI41243.1 - 5.8e-05 23.5 2.3 5.8e-05 23.5 2.3 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain KELK PF15796.5 KPI41243.1 - 3.2 8.3 9.4 0.33 11.5 2.3 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase adh_short PF00106.25 KPI41244.1 - 3.2e-41 140.9 1.6 8.7e-41 139.5 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41244.1 - 7.3e-40 137.0 0.5 9.7e-40 136.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41244.1 - 1.8e-10 41.0 0.3 2.5e-10 40.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI41244.1 - 0.00088 18.5 0.2 0.0012 18.0 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UQ_con PF00179.26 KPI41245.1 - 5.6e-09 35.8 0.0 9.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KPI41245.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Sugar_tr PF00083.24 KPI41247.1 - 8.1e-78 262.3 18.4 9.6e-78 262.0 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41247.1 - 2.3e-24 86.0 30.3 9.4e-17 61.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI41247.1 - 0.88 8.4 13.3 0.0093 14.9 5.4 1.6 2 0 0 2 2 2 0 MFS_1 like family Gly_transf_sug PF04488.15 KPI41249.1 - 3e-11 43.8 0.0 6.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPI41249.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Uricase PF01014.18 KPI41250.1 - 1.2e-57 193.8 4.2 1.2e-33 116.1 0.0 3.0 2 1 0 2 2 2 2 Uricase PAGK PF15284.6 KPI41250.1 - 0.23 11.4 1.1 2.4 8.2 0.1 2.3 1 1 1 2 2 2 0 Phage-encoded virulence factor PAP2 PF01569.21 KPI41251.1 - 2.8e-26 91.9 5.6 5.6e-26 90.9 5.6 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KPI41251.1 - 0.81 10.3 3.6 1.9 9.1 3.6 1.6 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Kelch_4 PF13418.6 KPI41252.1 - 0.00094 19.1 4.4 0.62 10.1 0.1 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain SKG6 PF08693.10 KPI41252.1 - 0.032 13.6 0.3 0.065 12.7 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FMO-like PF00743.19 KPI41254.1 - 7e-49 166.6 0.0 1.4e-48 165.7 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI41254.1 - 4.3e-16 59.1 0.0 2.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI41254.1 - 1.5e-06 27.7 0.0 4.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI41254.1 - 0.0012 18.0 0.5 0.013 14.7 0.0 2.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI41254.1 - 0.0033 17.4 0.1 6.3 6.8 0.4 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI41254.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI41254.1 - 0.13 11.8 0.1 2.3 7.7 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lipase_3 PF01764.25 KPI41255.1 - 5.9e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KPI41255.1 - 0.021 15.4 0.5 0.054 14.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KPI41255.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KPI41255.1 - 0.19 11.0 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KPI41255.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) p450 PF00067.22 KPI41256.1 - 1.4e-30 106.5 0.0 1.6e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Allantoicase PF03561.15 KPI41258.1 - 6.9e-89 295.2 1.4 1.1e-43 148.7 0.1 2.1 2 0 0 2 2 2 2 Allantoicase repeat Methyltransf_25 PF13649.6 KPI41259.1 - 1.5e-12 48.1 0.0 2.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI41259.1 - 8.7e-11 42.3 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI41259.1 - 3.8e-07 29.7 0.0 5.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KPI41259.1 - 4.3e-07 29.9 0.0 6.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI41259.1 - 0.00075 20.2 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI41259.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain BNR_3 PF13859.6 KPI41259.1 - 0.03 13.6 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DUF3950 PF13132.6 KPI41259.1 - 0.059 13.1 0.4 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Tannase PF07519.11 KPI41260.1 - 1.4e-17 63.8 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase RibD_C PF01872.17 KPI41261.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain F-box-like PF12937.7 KPI41261.1 - 0.0021 17.9 0.3 0.0021 17.9 0.3 1.7 2 0 0 2 2 2 1 F-box-like Cep57_MT_bd PF06657.13 KPI41261.1 - 0.015 15.7 0.3 0.031 14.7 0.3 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Glyco_transf_28 PF03033.20 KPI41262.1 - 1.8e-17 63.6 0.2 9.4e-11 41.9 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KPI41262.1 - 7.2e-06 25.1 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KPI41262.1 - 9.2e-05 22.7 0.0 0.00037 20.8 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KPI41262.1 - 0.0012 18.9 1.3 0.006 16.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 KPI41262.1 - 0.032 14.1 30.3 1.1 9.4 0.3 7.3 7 0 0 7 7 7 0 Ubiquitin interaction motif DNA_binding_1 PF01035.20 KPI41264.1 - 1.2e-23 83.1 0.1 1.4e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain BTB PF00651.31 KPI41265.1 - 0.00028 21.1 0.0 0.00072 19.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KPI41266.1 - 8.5e-11 41.4 14.4 8.5e-11 41.4 14.4 3.8 2 2 0 3 3 3 2 Major Facilitator Superfamily SAP25 PF15476.6 KPI41266.1 - 0.25 11.0 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP25 Sugar_tr PF00083.24 KPI41267.1 - 7e-94 315.2 17.5 2.3e-88 297.1 7.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI41267.1 - 6.8e-12 45.0 53.1 1.5e-08 34.0 22.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily HEAT_EZ PF13513.6 KPI41268.1 - 7.6e-05 23.1 3.1 0.00024 21.5 0.3 3.2 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 KPI41268.1 - 0.00023 21.5 8.8 0.00053 20.3 0.4 5.0 6 1 0 6 6 6 1 HEAT repeats HEAT PF02985.22 KPI41268.1 - 0.0061 16.7 14.1 0.017 15.3 0.0 5.8 8 0 0 8 8 8 2 HEAT repeat TAFH PF07531.14 KPI41268.1 - 0.077 13.1 0.1 5.3 7.2 0.0 2.8 2 0 0 2 2 2 0 NHR1 homology to TAF 14-3-3 PF00244.20 KPI41269.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 14-3-3 protein Glyco_hydro_38N PF01074.22 KPI41270.1 - 2.9e-87 292.7 2.2 5.2e-87 291.9 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KPI41270.1 - 1.3e-58 198.6 0.0 2.9e-58 197.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KPI41270.1 - 6.5e-27 93.5 0.1 1.4e-26 92.4 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KPI41270.1 - 6.6e-11 42.2 0.2 2e-10 40.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SPX PF03105.19 KPI41271.1 - 0.84 9.5 6.5 1.1 9.1 6.5 1.2 1 0 0 1 1 1 0 SPX domain Glyco_hydro_28 PF00295.17 KPI41272.1 - 4e-49 167.4 3.5 6.2e-49 166.8 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KPI41272.1 - 0.16 11.8 22.4 0.019 14.9 6.6 2.7 1 1 1 2 2 2 0 Right handed beta helix region Fungal_trans PF04082.18 KPI41273.1 - 9.1e-54 182.3 0.2 1.7e-53 181.4 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DEAD PF00270.29 KPI41274.1 - 2e-06 27.7 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase NACHT PF05729.12 KPI41274.1 - 0.00029 20.8 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KPI41274.1 - 0.0062 16.9 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI41274.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KPI41274.1 - 0.044 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KPI41274.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KPI41274.1 - 0.18 12.3 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KPI41274.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane_2 PF06472.15 KPI41275.1 - 8.8e-102 340.1 0.5 1.6e-101 339.3 0.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KPI41275.1 - 1.2e-17 64.7 0.0 3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KPI41275.1 - 1.9e-05 24.6 0.2 7.1e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 KPI41275.1 - 0.003 17.3 0.1 0.18 11.6 0.0 2.9 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 KPI41275.1 - 0.015 15.8 0.9 0.015 15.8 0.9 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KPI41275.1 - 0.017 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Reticulon PF02453.17 KPI41275.1 - 0.03 14.3 0.2 0.07 13.1 0.2 1.6 1 0 0 1 1 1 0 Reticulon Rad17 PF03215.15 KPI41275.1 - 0.031 14.2 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 KPI41275.1 - 0.038 13.4 1.3 0.087 12.2 0.0 2.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KPI41275.1 - 0.056 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KPI41275.1 - 0.088 12.5 0.1 0.27 10.9 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KPI41275.1 - 0.16 12.3 0.5 0.6 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain TGT PF01702.18 KPI41277.1 - 4.6e-138 460.2 0.0 2.3e-80 270.4 0.0 2.0 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Bac_surface_Ag PF01103.23 KPI41278.1 - 1.3e-26 93.9 0.6 3e-26 92.7 0.6 1.5 1 1 0 1 1 1 1 Surface antigen ShlB PF03865.13 KPI41278.1 - 0.00027 20.5 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB TIP41 PF04176.13 KPI41279.1 - 1e-67 226.9 0.0 1.4e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family T4SS PF07996.11 KPI41279.1 - 0.051 14.0 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins Ctr PF04145.15 KPI41280.1 - 3.5e-15 56.9 0.2 4.3e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family MFS_1 PF07690.16 KPI41281.1 - 8.1e-34 117.1 66.0 2.2e-31 109.1 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 KPI41282.1 - 2.5e-154 514.2 0.1 2.8e-154 514.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI41282.1 - 0.1 12.0 0.0 1.1 8.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) LuxC PF05893.14 KPI41282.1 - 0.13 11.3 0.0 0.5 9.4 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glyco_hydro_3_C PF01915.22 KPI41283.1 - 1e-58 198.7 0.0 1.7e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI41283.1 - 1.4e-40 139.6 0.0 2.2e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI41283.1 - 5.6e-26 90.5 0.4 1.4e-25 89.2 0.4 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KPI41283.1 - 2.3e-14 53.4 0.1 4.5e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 PA14 domain Yip1 PF04893.17 KPI41283.1 - 4.3e-05 23.3 5.0 0.0075 16.0 1.0 2.2 2 0 0 2 2 2 2 Yip1 domain Pro_isomerase PF00160.21 KPI41284.1 - 1.3e-29 103.5 0.0 2e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KPI41284.1 - 1.1e-15 57.2 0.1 2.3e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI41284.1 - 0.098 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L19 PF01245.20 KPI41286.1 - 9.4e-14 51.3 0.2 2.2e-13 50.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L19 Nup188_C PF18378.1 KPI41286.1 - 0.09 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain bZIP_2 PF07716.15 KPI41287.1 - 6.7 6.9 8.0 6.6 6.9 3.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper PRP4 PF08799.11 KPI41288.1 - 1.8e-06 27.4 4.8 1.1e-05 24.8 0.0 2.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.15 KPI41288.1 - 7.6e-06 26.0 1.0 2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain MFS_1 PF07690.16 KPI41289.1 - 8.3e-36 123.6 24.9 1.3e-35 123.0 24.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI41289.1 - 8.1e-06 25.4 3.1 8.1e-06 25.4 3.1 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Trp_oprn_chp PF09534.10 KPI41289.1 - 0.012 15.4 7.7 0.066 13.0 2.3 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 KPI41291.1 - 1.3e-43 149.3 39.7 1.3e-43 149.3 39.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41291.1 - 7.9e-17 61.2 16.0 1.2e-14 54.1 2.7 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KPI41291.1 - 0.00035 19.1 6.1 0.00035 19.1 6.1 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector Zip PF02535.22 KPI41291.1 - 0.046 12.9 4.0 0.12 11.6 0.7 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter OATP PF03137.20 KPI41291.1 - 2.8 6.1 7.0 5.1 5.3 0.9 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Isochorismatase PF00857.20 KPI41292.1 - 1.5e-21 77.4 0.0 2.3e-21 76.7 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Acetyltransf_7 PF13508.7 KPI41293.1 - 1.9e-08 34.6 0.0 5.6e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI41293.1 - 2.2e-07 31.1 0.0 6.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI41293.1 - 1.7e-06 28.0 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI41293.1 - 0.0027 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Tubulin_3 PF14881.6 KPI41294.1 - 6.7e-77 257.2 0.1 1.2e-76 256.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KPI41294.1 - 3.5e-38 130.5 0.0 8.2e-38 129.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KPI41294.1 - 0.00013 22.2 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain AtuA PF07287.11 KPI41295.1 - 5.2e-125 416.8 0.1 6.3e-125 416.5 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ABC2_membrane PF01061.24 KPI41296.1 - 4.2e-78 261.6 50.0 8.8e-41 139.6 20.0 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KPI41296.1 - 1e-37 129.7 0.0 4.8e-18 66.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KPI41296.1 - 2.8e-32 110.5 3.3 8.1e-26 89.8 0.2 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KPI41296.1 - 6e-17 62.0 0.1 1.7e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KPI41296.1 - 2.5e-07 30.1 43.8 6.9e-06 25.4 22.8 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KPI41296.1 - 3e-06 27.4 0.1 0.0032 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KPI41296.1 - 6.7e-06 25.8 0.2 8e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI41296.1 - 3.3e-05 23.9 0.1 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KPI41296.1 - 8.5e-05 23.0 0.0 0.009 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KPI41296.1 - 0.0004 20.9 0.1 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KPI41296.1 - 0.0015 18.2 1.9 0.068 12.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KPI41296.1 - 0.0047 16.7 1.6 0.051 13.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KPI41296.1 - 0.015 15.1 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPI41296.1 - 0.015 15.5 1.3 1.9 8.8 0.3 2.8 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 KPI41296.1 - 0.043 13.7 0.1 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KPI41296.1 - 0.045 13.7 1.9 2.8 7.8 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KPI41296.1 - 0.079 12.7 3.1 1.2 8.8 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF751 PF05421.11 KPI41296.1 - 0.093 13.5 10.3 0.3 11.9 7.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF751) MMR_HSR1 PF01926.23 KPI41296.1 - 0.1 12.7 0.5 19 5.3 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase SMC_N PF02463.19 KPI41296.1 - 0.12 11.8 0.0 1.7 8.0 0.0 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KPI41296.1 - 0.13 12.7 0.4 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI41296.1 - 0.15 11.8 0.7 16 5.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 KPI41297.1 - 2e-13 50.2 0.1 2.9e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI41297.1 - 1e-10 42.6 0.0 1.2e-10 42.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI41297.1 - 4.1e-10 39.7 0.0 6.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KPI41297.1 - 0.00024 21.3 0.0 0.00064 19.9 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KPI41297.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PDEase_II PF02112.15 KPI41298.1 - 1.9e-49 168.6 0.0 2.9e-22 79.2 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II DnaJ PF00226.31 KPI41299.1 - 5.6e-20 71.2 3.0 5.6e-20 71.2 3.0 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KPI41299.1 - 5.9e-17 60.7 7.8 0.0042 16.9 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KPI41299.1 - 1.4e-13 49.8 14.5 0.054 13.6 0.0 8.3 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KPI41299.1 - 1.9e-10 40.7 6.9 0.00044 20.4 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPI41299.1 - 9.1e-10 38.9 16.7 1.6e-06 28.6 1.4 5.6 4 3 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KPI41299.1 - 9.2e-09 35.4 9.9 0.47 11.4 0.3 6.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI41299.1 - 7.3e-08 32.0 13.3 0.33 11.3 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI41299.1 - 7.5e-06 26.5 16.1 0.0083 16.7 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPI41299.1 - 0.00025 20.7 6.9 0.6 9.8 0.1 5.4 5 2 0 5 5 5 2 TPR repeat TPR_6 PF13174.6 KPI41299.1 - 0.00051 20.5 10.4 4.3 8.2 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KPI41299.1 - 0.00059 18.7 2.4 0.0064 15.3 0.4 2.3 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 KPI41299.1 - 0.017 15.4 2.6 0.017 15.4 2.6 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KPI41299.1 - 0.031 14.7 5.1 0.07 13.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPI41299.1 - 0.039 14.0 2.8 48 4.3 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI41299.1 - 0.73 10.2 14.1 1.4 9.2 0.3 5.1 4 3 0 4 4 4 0 Tetratricopeptide repeat Cupin_1 PF00190.22 KPI41300.1 - 9.5e-41 138.9 0.0 8.2e-20 70.9 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KPI41300.1 - 3.6e-24 84.2 0.8 5e-12 45.3 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KPI41300.1 - 1.4e-08 34.3 0.0 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KPI41300.1 - 1.6e-07 31.3 0.1 0.00024 21.0 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KPI41300.1 - 2.9e-05 24.0 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.14 KPI41300.1 - 0.00013 22.2 0.2 0.04 14.1 0.1 2.2 2 0 0 2 2 2 2 ARD/ARD' family CENP-C_C PF11699.8 KPI41300.1 - 0.013 15.7 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Mif2/CENP-C like 3-HAO PF06052.12 KPI41300.1 - 0.026 14.2 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.12 KPI41300.1 - 0.096 12.9 0.0 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Ectoine synthase adh_short PF00106.25 KPI41301.1 - 2.6e-16 59.7 0.5 3.6e-16 59.2 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41301.1 - 6e-10 39.1 0.3 6.9e-10 38.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41301.1 - 0.00052 20.0 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Nucleopor_Nup85 PF07575.13 KPI41302.1 - 2.4e-26 92.5 2.0 1.7e-17 63.3 0.0 3.2 3 0 0 3 3 3 3 Nup85 Nucleoporin IBN_N PF03810.19 KPI41303.1 - 6.7e-12 45.2 1.3 9e-11 41.5 0.3 2.9 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KPI41303.1 - 3.8e-07 30.3 0.2 9.1e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Exportin 1-like protein Seipin PF06775.14 KPI41304.1 - 2.6e-51 174.5 0.1 3.8e-51 174.0 0.1 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) ER_lumen_recept PF00810.18 KPI41304.1 - 4.5e-40 137.8 8.5 4.5e-40 137.8 8.5 2.3 3 0 0 3 3 3 1 ER lumen protein retaining receptor Acetyltransf_3 PF13302.7 KPI41305.1 - 6e-06 27.0 0.0 1.4e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPI41305.1 - 0.076 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_42 PF02449.15 KPI41306.1 - 0.033 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase F-box PF00646.33 KPI41307.1 - 0.11 12.4 0.2 0.33 10.9 0.2 1.9 1 0 0 1 1 1 0 F-box domain zf-C2H2 PF00096.26 KPI41308.1 - 0.18 12.3 0.2 0.31 11.6 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KPI41308.1 - 0.3 11.7 1.7 0.28 11.8 0.3 1.7 1 1 1 2 2 2 0 FOXP coiled-coil domain YabA PF06156.13 KPI41308.1 - 3.6 8.3 7.8 2.5 8.8 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA GIT_SHD PF08518.11 KPI41309.1 - 5.1e-22 77.2 2.3 2.9e-14 52.4 0.5 3.2 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Exonuc_VII_L PF02601.15 KPI41309.1 - 0.41 10.2 25.5 1.8 8.0 12.9 3.2 2 1 0 2 2 2 0 Exonuclease VII, large subunit CENP-K PF11802.8 KPI41309.1 - 2.7 7.5 13.7 4.1 6.9 10.3 2.5 2 0 0 2 2 2 0 Centromere-associated protein K HsbA PF12296.8 KPI41309.1 - 3.1 8.3 10.1 0.83 10.1 3.6 3.3 4 0 0 4 4 4 0 Hydrophobic surface binding protein A Brr6_like_C_C PF10104.9 KPI41310.1 - 1.4e-41 141.4 2.6 1.8e-41 141.0 2.6 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain NADHdh_A3 PF14987.6 KPI41310.1 - 8.1 6.8 8.7 0.23 11.8 2.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 UQ_con PF00179.26 KPI41311.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Gag_p12 PF01141.18 KPI41311.1 - 0.001 19.3 1.4 0.14 12.5 0.1 2.6 3 0 0 3 3 3 2 Gag polyprotein, inner coat protein p12 AAA PF00004.29 KPI41312.1 - 3e-17 63.3 0.0 8.7e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI41312.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KPI41312.1 - 0.17 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SYS1 PF09801.9 KPI41313.1 - 5e-37 127.3 4.9 7.3e-37 126.7 4.9 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.12 KPI41313.1 - 3 7.8 8.6 0.24 11.4 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PDCD2_C PF04194.13 KPI41314.1 - 1.4e-43 149.0 0.1 1.2e-42 146.0 0.0 2.1 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Auts2 PF15336.6 KPI41314.1 - 0.028 14.6 7.4 0.041 14.0 7.4 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Peptidase_S41_N PF11918.8 KPI41314.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Polysacc_deac_1 PF01522.21 KPI41315.1 - 7.9e-11 41.9 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPI41315.1 - 2.7e-06 27.2 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KPI41315.1 - 0.15 10.3 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Amino_oxidase PF01593.24 KPI41316.1 - 3.4e-50 171.6 0.0 3.1e-41 142.1 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI41316.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Tautomerase PF01361.21 KPI41317.1 - 1.9e-07 30.9 0.0 3.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 KPI41317.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Tautomerase enzyme DUF917 PF06032.12 KPI41319.1 - 1.5e-84 283.9 0.0 1.6e-54 185.1 0.0 3.0 3 1 1 4 4 4 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KPI41319.1 - 2.1e-33 115.5 3.7 4e-30 104.8 0.4 3.0 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPI41319.1 - 3.9e-26 92.0 6.0 2.2e-23 82.9 0.2 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KPI41319.1 - 7.5e-07 28.1 2.5 0.00048 18.8 0.1 2.3 2 0 0 2 2 2 2 MutL protein ROK PF00480.20 KPI41319.1 - 0.00012 21.7 0.3 0.00025 20.6 0.3 1.5 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 KPI41319.1 - 0.006 16.1 0.3 0.006 16.1 0.3 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KPI41319.1 - 0.0062 16.9 3.0 0.25 11.8 0.0 3.3 2 1 0 2 2 2 1 Cell division protein FtsA StbA PF06406.11 KPI41319.1 - 0.29 10.3 3.6 1.7 7.8 0.1 2.7 3 0 0 3 3 3 0 StbA protein RTA1 PF04479.13 KPI41321.1 - 1.7e-53 181.3 14.7 1.7e-53 181.3 14.7 1.4 2 0 0 2 2 2 1 RTA1 like protein UPF0220 PF05255.11 KPI41321.1 - 0.0062 16.1 6.1 0.013 15.0 6.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ODV-E18 PF10717.9 KPI41321.1 - 0.076 12.9 0.6 7.1 6.6 0.1 2.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Deltameth_res PF16020.5 KPI41321.1 - 8.3 6.4 6.5 3.6 7.5 1.2 2.8 1 1 1 2 2 2 0 Deltamethrin resistance LCAT PF02450.15 KPI41322.1 - 0.0063 15.7 0.0 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KPI41322.1 - 0.026 14.0 0.1 0.21 11.1 0.0 2.3 3 0 0 3 3 3 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KPI41322.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI41322.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ETS_PEA3_N PF04621.13 KPI41324.1 - 0.2 11.5 20.8 0.35 10.7 19.4 1.8 1 1 1 2 2 2 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Metallophos PF00149.28 KPI41325.1 - 2.1e-09 38.2 1.8 4.6e-09 37.1 1.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KPI41325.1 - 0.00013 22.2 0.0 0.0067 16.7 0.0 2.9 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain AhpC-TSA PF00578.21 KPI41326.1 - 6.8e-26 90.6 0.0 9e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KPI41326.1 - 3.3e-21 75.5 0.0 3.4e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 Redoxin DUF899 PF05988.12 KPI41326.1 - 0.0037 16.8 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 KPI41326.1 - 0.013 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 KPI41326.1 - 0.026 14.9 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like XPG_I PF00867.18 KPI41327.1 - 1e-20 73.9 0.1 2.2e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KPI41327.1 - 2.7e-06 27.8 0.0 6.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KPI41327.1 - 0.0054 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing NifU_N PF01592.16 KPI41328.1 - 1.1e-55 187.2 0.1 1.6e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1858 PF08984.11 KPI41328.1 - 0.051 13.7 0.1 0.24 11.6 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1858) TSCPD PF12637.7 KPI41328.1 - 0.088 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain AMP-binding PF00501.28 KPI41329.1 - 7.6e-33 113.7 0.0 9.3e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI41329.1 - 3.2e-11 44.1 0.1 6.5e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribonuc_red_lgC PF02867.15 KPI41330.1 - 6.3e-188 625.6 0.0 8.5e-188 625.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KPI41330.1 - 6.2e-23 80.6 0.0 1.5e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KPI41330.1 - 1.4e-16 60.8 0.0 2.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain Nodulin_late PF07127.11 KPI41331.1 - 0.014 15.7 8.5 0.49 10.8 0.1 3.2 3 0 0 3 3 3 0 Late nodulin protein Gamma-thionin PF00304.20 KPI41331.1 - 0.2 12.0 33.9 1 9.7 4.3 3.5 3 0 0 3 3 3 0 Gamma-thionin family TFIIA PF03153.13 KPI41332.1 - 4.4e-56 191.7 17.8 6e-53 181.3 17.8 2.2 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MbeD_MobD PF04899.12 KPI41332.1 - 0.2 11.8 1.6 8.5 6.6 0.1 2.6 2 0 0 2 2 2 0 MbeD/MobD like RCC1 PF00415.18 KPI41333.1 - 3.3e-32 110.9 15.9 2e-08 34.7 0.0 7.2 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KPI41333.1 - 4e-22 77.5 27.8 1.5e-08 34.2 0.3 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ENOD93 PF03386.14 KPI41333.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Acetyltransf_10 PF13673.7 KPI41334.1 - 2.1e-05 24.5 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI41334.1 - 0.00013 22.3 0.0 0.00016 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI41334.1 - 0.0039 17.4 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPT PF03151.16 KPI41335.1 - 1.3e-06 28.0 16.3 2.6e-06 27.0 16.3 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KPI41335.1 - 1.6e-06 28.3 13.3 1.6e-06 28.3 13.3 2.3 2 1 0 2 2 2 1 EamA-like transporter family TRI9 PF08195.11 KPI41335.1 - 0.22 11.5 0.9 0.65 9.9 0.4 2.0 2 0 0 2 2 2 0 TRI9 protein DUF4405 PF14358.6 KPI41335.1 - 1.1 9.8 0.1 1.1 9.8 0.1 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4405) LapA_dom PF06305.11 KPI41335.1 - 3.8 7.4 6.2 8.3 6.3 0.1 3.4 2 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4872 PF16169.5 KPI41337.1 - 0.097 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) CHZ PF09649.10 KPI41338.1 - 1.1e-11 44.0 5.0 1.1e-11 44.0 5.0 2.6 3 1 0 3 3 3 1 Histone chaperone domain CHZ CDC27 PF09507.10 KPI41338.1 - 7.7 5.8 20.6 8.3 5.7 20.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DIOX_N PF14226.6 KPI41339.1 - 1.2e-18 68.0 0.0 3.1e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI41339.1 - 4.9e-15 55.8 0.0 8.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_7 PF03441.14 KPI41340.1 - 1.1e-54 185.0 1.1 2e-54 184.2 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPI41340.1 - 2e-39 135.2 0.1 4.9e-39 134.0 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase S_100 PF01023.19 KPI41340.1 - 1 9.1 4.8 3.5 7.4 0.2 3.2 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain GerPC PF10737.9 KPI41341.1 - 0.17 11.9 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Spore germination protein GerPC Preseq_ALAS PF09029.10 KPI41342.1 - 0.0015 19.0 1.9 0.13 12.8 0.9 2.2 1 1 1 2 2 2 2 5-aminolevulinate synthase presequence Ribosomal_S9 PF00380.19 KPI41343.1 - 5.4e-34 117.3 0.4 6.1e-34 117.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Peptidase_S10 PF00450.22 KPI41344.1 - 7.6e-69 233.1 0.4 9.8e-69 232.8 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HET PF06985.11 KPI41346.1 - 8.1e-22 78.2 2.3 1.4e-21 77.3 2.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rick_17kDa_Anti PF05433.15 KPI41348.1 - 0.69 9.8 6.6 1.5 8.7 0.5 2.6 3 0 0 3 3 3 0 Glycine zipper 2TM domain Glyco_hydro_76 PF03663.14 KPI41350.1 - 3.8e-23 82.6 3.7 1.1e-16 61.3 0.2 2.9 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 Fungal_trans PF04082.18 KPI41351.1 - 6.6e-13 48.3 0.0 9.2e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ALIX_LYPXL_bnd PF13949.6 KPI41352.1 - 3.3e-60 203.9 15.2 4.9e-60 203.3 15.2 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 KPI41352.1 - 0.031 13.7 0.3 0.07 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DUF1128 PF06569.11 KPI41352.1 - 0.097 12.7 2.1 0.12 12.3 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) TadF PF16964.5 KPI41352.1 - 0.1 12.3 1.2 0.22 11.3 1.2 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF4119 PF13494.6 KPI41352.1 - 0.16 12.1 1.4 0.44 10.7 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) DEAD PF00270.29 KPI41353.1 - 1.7e-39 135.4 0.5 1e-19 71.0 0.2 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI41353.1 - 2.4e-20 72.9 0.1 1.2e-18 67.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI41353.1 - 5.1e-10 39.6 0.0 2.6e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KPI41353.1 - 0.0031 16.3 0.0 0.14 11.0 0.0 2.2 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 KPI41353.1 - 0.028 14.8 0.0 0.07 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KPI41353.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain cNMP_binding PF00027.29 KPI41354.1 - 3.8e-37 126.3 0.0 1.4e-18 66.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KPI41354.1 - 1.4e-07 31.0 0.2 2.7e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Mak16 PF04874.14 KPI41354.1 - 0.095 13.3 0.2 0.84 10.3 0.1 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region COX6B PF02297.17 KPI41355.1 - 3.6e-22 78.4 4.0 4.6e-22 78.0 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0158 PF03682.13 KPI41355.1 - 0.023 14.7 0.5 0.028 14.4 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) TRM PF02005.16 KPI41357.1 - 1.7e-104 350.0 0.0 2.7e-92 309.8 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase TFIIA PF03153.13 KPI41357.1 - 0.0067 16.5 1.4 0.01 15.9 1.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Met_10 PF02475.16 KPI41357.1 - 0.0085 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cyto_heme_lyase PF01265.17 KPI41358.1 - 1.5e-106 356.2 1.4 3.1e-106 355.2 1.4 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase CP2 PF04516.15 KPI41359.1 - 4.6e-76 255.1 0.0 8.2e-76 254.3 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KPI41359.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Tektin family Mit_KHE1 PF10173.9 KPI41359.1 - 0.35 10.9 2.3 0.4 10.7 0.9 1.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related SRP-alpha_N PF04086.13 KPI41359.1 - 9.4 6.1 8.0 0.72 9.7 0.9 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Glyco_hydro_10 PF00331.20 KPI41360.1 - 7.6e-109 363.7 2.9 8.7e-109 363.5 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KPI41360.1 - 0.071 12.4 0.1 0.32 10.3 0.0 1.9 1 1 1 2 2 2 0 Beta-galactosidase DEAD PF00270.29 KPI41361.1 - 1.3e-49 168.3 0.0 8.7e-49 165.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI41361.1 - 8.7e-31 106.5 0.0 6.6e-30 103.7 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI41361.1 - 4.2e-05 23.6 0.0 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KPI41361.1 - 0.0015 17.8 0.1 0.0022 17.2 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KPI41361.1 - 0.0019 18.6 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KPI41361.1 - 0.0083 15.9 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.6 KPI41361.1 - 0.0083 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF5335 PF17269.2 KPI41361.1 - 0.011 15.5 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) UTP25 PF06862.12 KPI41361.1 - 0.018 13.8 0.1 0.76 8.5 0.0 2.3 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ribonuc_L-PSP PF01042.21 KPI41362.1 - 2.9e-16 59.6 0.0 4.2e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP HMG-CoA_red PF00368.18 KPI41363.1 - 1.8e-140 468.1 4.4 2.9e-140 467.4 4.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KPI41363.1 - 1.3e-43 148.6 1.9 2.3e-43 147.8 1.9 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif adh_short PF00106.25 KPI41363.1 - 7.3e-35 120.2 0.2 1.6e-34 119.1 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41363.1 - 5e-20 72.0 0.2 1.3e-19 70.7 0.2 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sterol-sensing PF12349.8 KPI41363.1 - 2.3e-13 50.3 4.4 1.7e-06 28.0 0.6 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation DUF1776 PF08643.10 KPI41363.1 - 5.4e-07 29.3 0.0 4e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Patched PF02460.18 KPI41363.1 - 1.6e-06 26.6 3.4 3.1e-06 25.6 3.4 1.4 1 0 0 1 1 1 1 Patched family NAD_binding_10 PF13460.6 KPI41363.1 - 8.5e-06 25.8 0.1 6.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding FAD_binding_3 PF01494.19 KPI41363.1 - 0.054 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KPI41363.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KPI41363.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldedh PF00171.22 KPI41364.1 - 4.9e-123 411.0 2.6 5.5e-123 410.9 2.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-C2H2 PF00096.26 KPI41365.1 - 9.3e-07 29.0 21.6 0.0007 19.9 4.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI41365.1 - 3e-06 27.4 9.5 5.7e-05 23.3 3.7 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI41365.1 - 0.02 15.7 20.3 0.049 14.5 3.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI41365.1 - 0.03 14.6 0.2 0.11 12.8 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KPI41365.1 - 0.066 13.8 1.4 0.22 12.1 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KPI41365.1 - 6.1 6.7 14.2 3.1 7.6 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Bud13 PF09736.9 KPI41366.1 - 5.7e-43 146.8 13.2 5.7e-43 146.8 13.2 3.2 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.6 KPI41366.1 - 0.4 11.0 5.0 0.72 10.1 5.0 1.5 1 0 0 1 1 1 0 SPATIAL NUDIX PF00293.28 KPI41367.1 - 5e-10 39.5 0.2 1.3e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain PHINT_rpt PF14882.6 KPI41367.1 - 0.12 12.7 1.9 0.35 11.2 1.9 1.8 1 0 0 1 1 1 0 Phage-integrase repeat unit TRM13 PF05206.14 KPI41367.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 RCC1 PF00415.18 KPI41368.1 - 2.5e-27 95.2 2.5 3.7e-07 30.7 0.0 7.0 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KPI41368.1 - 4.3e-14 51.9 21.3 1.5e-08 34.2 0.1 7.2 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat HDC PF02329.16 KPI41368.1 - 0.085 11.9 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine carboxylase PI chain Beach PF02138.18 KPI41369.1 - 9.7e-121 402.4 0.0 1.5e-120 401.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KPI41369.1 - 4.1e-11 42.9 0.3 2.7e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH eIF-5a PF01287.20 KPI41369.1 - 8.1e-05 22.6 0.0 0.00031 20.8 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WD40 PF00400.32 KPI41369.1 - 0.07 14.0 0.1 15 6.6 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat ATP_sub_h PF10775.9 KPI41369.1 - 0.097 12.7 0.1 10 6.2 0.0 2.7 2 0 0 2 2 2 0 ATP synthase complex subunit h RCR PF12273.8 KPI41369.1 - 0.56 10.9 1.9 0.66 10.6 0.2 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF4800 PF16057.5 KPI41369.1 - 3.6 6.8 7.6 0.65 9.2 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4800) Ydc2-catalyt PF09159.10 KPI41370.1 - 1.3e-68 231.7 0.0 1.8e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KPI41370.1 - 1.1e-05 25.6 0.0 0.83 9.8 0.0 3.2 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.27 KPI41370.1 - 0.002 17.8 0.2 0.006 16.3 0.2 1.8 1 0 0 1 1 1 1 SAP domain Abhydrolase_1 PF00561.20 KPI41371.1 - 1.3e-16 61.1 0.0 4.6e-14 52.7 0.0 3.3 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI41371.1 - 6.3e-16 58.4 0.2 2.2e-15 56.6 0.2 1.9 1 1 0 1 1 1 1 TAP-like protein WH1 PF00568.23 KPI41372.1 - 7.2e-26 90.3 0.0 1.1e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KPI41372.1 - 0.0073 16.1 7.7 0.049 13.5 7.7 2.2 1 1 0 1 1 1 1 WH2 motif Epimerase PF01370.21 KPI41373.1 - 8.1e-19 68.0 0.0 1.1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI41373.1 - 5.4e-12 45.7 0.0 1.4e-10 41.1 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI41373.1 - 8.2e-10 38.1 0.0 9.5e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KPI41373.1 - 4.7e-06 25.9 0.0 1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPI41373.1 - 4.3e-05 22.8 0.0 0.03 13.5 0.1 2.7 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KPI41373.1 - 0.0036 16.5 0.0 0.019 14.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KPI41373.1 - 0.0046 17.1 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KPI41373.1 - 0.036 14.0 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 KPI41373.1 - 0.049 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KPI41373.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF1690 PF07956.11 KPI41374.1 - 2.9e-34 118.5 10.3 1.2e-33 116.5 10.3 1.8 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 KPI41374.1 - 0.0098 15.9 0.5 0.0098 15.9 0.5 1.9 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion RPW8 PF05659.11 KPI41374.1 - 0.02 14.6 2.1 0.021 14.5 0.7 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Com_YlbF PF06133.11 KPI41374.1 - 0.26 11.9 6.5 5.5 7.6 0.9 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA G-gamma PF00631.22 KPI41374.1 - 3.4 7.7 6.6 0.37 10.8 0.7 2.4 3 0 0 3 3 3 0 GGL domain Hydant_A_N PF05378.13 KPI41376.1 - 1.6e-07 31.2 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Sugar_tr PF00083.24 KPI41377.1 - 1.4e-77 261.5 21.8 1.7e-77 261.3 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41377.1 - 7.8e-17 61.2 36.9 5.1e-08 32.2 16.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI41377.1 - 1.9 7.2 15.0 0.032 13.1 3.0 2.7 2 1 1 3 3 3 0 MFS_1 like family DUF3792 PF12670.7 KPI41377.1 - 2.8 8.1 22.4 1.3 9.2 4.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) DUF2518 PF10726.9 KPI41379.1 - 0.2 11.3 0.2 0.34 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of function (DUF2518) Grg1 PF11034.8 KPI41381.1 - 3.8e-30 103.9 15.3 4.3e-30 103.7 15.3 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Fungal_trans_2 PF11951.8 KPI41383.1 - 0.0097 14.8 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_22 PF03901.17 KPI41384.1 - 1.8e-61 208.7 21.8 2.1e-61 208.5 21.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family POP1 PF06978.11 KPI41386.1 - 1.9e-68 230.5 25.8 5.3e-68 229.1 25.8 1.8 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KPI41386.1 - 9.6e-27 93.2 0.6 9.6e-27 93.2 0.6 2.9 2 0 0 2 2 2 1 POPLD (NUC188) domain Ferric_reduct PF01794.19 KPI41387.1 - 5.6e-19 68.5 4.4 5.6e-19 68.5 4.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KPI41387.1 - 3.5e-06 27.1 0.0 7.6e-05 22.8 0.0 2.7 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KPI41387.1 - 0.00013 22.1 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KPI41387.1 - 0.037 14.7 0.0 0.076 13.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Mpv17_PMP22 PF04117.12 KPI41388.1 - 2.2e-19 69.5 0.7 1.7e-18 66.6 0.2 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family p450 PF00067.22 KPI41389.1 - 2.1e-46 158.7 0.0 6.8e-33 114.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RRM_2 PF04059.12 KPI41391.1 - 4.5e-35 119.7 0.1 7.7e-35 119.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KPI41391.1 - 0.0019 18.0 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Epimerase PF01370.21 KPI41392.1 - 4.5e-23 82.0 0.0 1.7e-22 80.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI41392.1 - 1.1e-14 54.7 0.0 2.9e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI41392.1 - 5.6e-07 28.8 0.0 3.1e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPI41392.1 - 9.3e-06 25.0 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KPI41392.1 - 1.6e-05 24.2 0.0 3e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KPI41392.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KPI41392.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Alpha-amylase PF00128.24 KPI41393.1 - 2e-17 63.8 1.5 9.4e-17 61.6 1.4 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KPI41393.1 - 8e-15 55.2 0.1 1.4e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KPI41393.1 - 0.0031 17.1 0.0 0.53 9.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPI41393.1 - 0.036 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 F-box PF00646.33 KPI41394.1 - 0.03 14.2 0.0 0.15 11.9 0.0 2.3 1 0 0 1 1 1 0 F-box domain UFD1 PF03152.14 KPI41394.1 - 0.2 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 PTR2 PF00854.21 KPI41396.1 - 7.8e-21 74.4 0.1 1.2e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 POT family Fungal_trans PF04082.18 KPI41396.1 - 6.6e-20 71.2 2.5 1.3e-19 70.3 2.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI41396.1 - 0.0001 22.3 12.6 0.0001 22.3 12.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KPI41397.1 - 2.2e-80 270.4 0.0 2.8e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI41397.1 - 6.8e-15 55.8 0.6 1.5e-14 54.7 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 KPI41398.1 - 1.5e-56 191.6 2.9 1.8e-56 191.4 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI41398.1 - 6.2e-41 140.0 0.5 8.7e-41 139.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KPI41398.1 - 0.0071 17.0 0.1 0.014 16.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KPI41398.1 - 0.011 15.7 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 KR domain MOZ_SAS PF01853.18 KPI41398.1 - 0.064 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family SWIRM-assoc_3 PF16498.5 KPI41398.1 - 0.11 12.8 0.6 0.24 11.7 0.6 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal DUF4212 PF13937.6 KPI41399.1 - 0.044 14.1 0.6 0.069 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) PHD PF00628.29 KPI41400.1 - 2.5e-09 36.9 1.8 2.5e-09 36.9 1.8 1.8 2 0 0 2 2 2 1 PHD-finger zf-CW PF07496.15 KPI41400.1 - 0.0066 16.5 1.5 0.014 15.4 1.5 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger PHD_2 PF13831.6 KPI41400.1 - 0.012 15.1 2.0 0.012 15.1 2.0 2.1 2 0 0 2 2 2 0 PHD-finger UIM PF02809.20 KPI41400.1 - 0.013 15.4 0.7 0.03 14.2 0.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif VSP PF03302.13 KPI41401.1 - 4.9e-05 22.4 2.2 6.9e-05 21.9 2.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 KPI41401.1 - 0.11 11.9 0.5 0.34 10.4 0.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WSC PF01822.19 KPI41402.1 - 1.7e-09 37.8 10.3 3.9e-09 36.6 10.3 1.6 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.11 KPI41402.1 - 0.037 14.1 0.8 0.1 12.7 0.6 1.8 2 0 0 2 2 2 0 Podoplanin CYYR1 PF10873.8 KPI41402.1 - 0.038 14.4 0.4 0.038 14.4 0.4 2.4 2 1 1 3 3 3 0 Cysteine and tyrosine-rich protein 1 Adeno_E3_CR2 PF02439.15 KPI41402.1 - 0.045 13.5 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KPI41402.1 - 0.05 14.5 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KPI41402.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Meckelin PF09773.9 KPI41402.1 - 0.18 9.9 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) PTP_tm PF18861.1 KPI41402.1 - 0.19 11.7 5.7 0.32 11.0 5.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 KPI41402.1 - 0.49 9.9 5.2 0.98 8.9 5.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DHHC PF01529.20 KPI41403.1 - 1.9e-21 76.6 7.7 1.9e-21 76.6 7.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Coiled-coil_56 PF09813.9 KPI41403.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 MMtag PF10159.9 KPI41404.1 - 1.4e-33 115.0 1.6 1.4e-33 115.0 1.6 2.3 2 0 0 2 2 2 1 Multiple myeloma tumor-associated Cyclase PF04199.13 KPI41405.1 - 1.4e-15 57.7 0.2 2e-15 57.2 0.2 1.3 1 0 0 1 1 1 1 Putative cyclase DUF5490 PF17593.2 KPI41405.1 - 0.037 14.0 0.3 0.09 12.8 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Haem_oxygenas_2 PF14518.6 KPI41405.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Iron-containing redox enzyme F-box-like PF12937.7 KPI41406.1 - 0.2 11.6 1.2 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 F-box-like Zn_clus PF00172.18 KPI41407.1 - 3.4e-09 36.7 9.1 7.8e-09 35.5 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI41407.1 - 1.7e-05 24.0 0.4 9.2e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPI41409.1 - 3.7e-84 283.2 16.9 4.3e-84 283.0 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41409.1 - 2.7e-19 69.3 33.0 7.4e-13 48.1 16.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mod_r PF07200.13 KPI41412.1 - 1.5 8.9 16.0 5.9e+02 0.5 16.0 3.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 KPI41412.1 - 3.1 8.5 8.7 2.8 8.6 0.6 3.5 2 0 0 2 2 2 0 SlyX ZapB PF06005.12 KPI41412.1 - 4.2 7.9 17.1 8.2 6.9 0.2 4.8 2 1 0 2 2 2 0 Cell division protein ZapB SOGA PF11365.8 KPI41412.1 - 6.6 7.9 13.1 48 5.2 5.4 3.7 2 0 0 2 2 2 0 Protein SOGA UQ_con PF00179.26 KPI41413.1 - 8.5e-47 158.3 0.0 9.5e-47 158.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPI41413.1 - 0.0009 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KPI41413.1 - 0.017 15.0 0.1 0.031 14.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KPI41413.1 - 0.078 13.3 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain IMS PF00817.20 KPI41414.1 - 1.4e-36 125.7 0.0 2.6e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KPI41414.1 - 9e-14 50.8 0.5 1.6e-13 49.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KPI41414.1 - 1.6e-09 38.5 0.0 3.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KPI41414.1 - 0.0015 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF2197 PF09963.9 KPI41414.1 - 0.012 15.9 0.0 0.035 14.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Pyr_redox_2 PF07992.14 KPI41415.1 - 1.1e-23 83.9 0.1 1.5e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI41415.1 - 6.4e-06 26.6 1.5 1.2e-05 25.8 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI41415.1 - 2e-05 24.0 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI41415.1 - 0.14 11.2 1.2 1.5 7.8 0.5 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A Myosin_N PF02736.19 KPI41415.1 - 2.6 7.9 4.3 11 5.9 0.3 2.7 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DUF3425 PF11905.8 KPI41416.1 - 9.5e-14 51.4 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI41416.1 - 0.00022 21.2 3.5 0.00045 20.3 3.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI41416.1 - 0.022 14.9 4.9 0.043 13.9 4.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper eIF-1a PF01176.19 KPI41417.1 - 3.8e-22 77.9 0.0 5.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Transp_cyt_pur PF02133.15 KPI41418.1 - 6.2e-82 275.7 29.4 3.4e-81 273.3 29.4 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Zn_clus PF00172.18 KPI41419.1 - 7.6e-07 29.2 12.0 1.8e-06 28.0 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI41419.1 - 8.1e-06 24.9 2.2 8.5e-06 24.8 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HLH PF00010.26 KPI41420.1 - 4.4e-10 39.3 0.2 1.3e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ADIP PF11559.8 KPI41420.1 - 0.0014 18.8 0.4 0.0014 18.8 0.4 1.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KPI41420.1 - 0.019 15.5 0.6 0.019 15.5 0.6 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 KPI41420.1 - 2.1 8.1 8.5 0.098 12.5 0.9 2.1 2 1 0 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 KPI41420.1 - 2.4 8.6 7.0 0.62 10.6 2.9 2.2 2 0 0 2 2 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 KPI41420.1 - 2.5 8.1 9.8 0.075 13.1 2.0 2.4 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 KPI41420.1 - 2.7 7.9 5.7 1.2 9.0 1.3 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region S1FA PF04689.13 KPI41421.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 DNA binding protein S1FA Peptidase_S8 PF00082.22 KPI41422.1 - 2e-36 125.8 7.4 3.4e-36 125.0 7.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KPI41422.1 - 3.9e-17 62.7 0.1 7.8e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.32 KPI41424.1 - 9.4e-10 38.9 14.8 0.0023 18.7 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 KPI41424.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 RWD domain ADH_N PF08240.12 KPI41425.1 - 9.2e-17 60.9 0.5 1.8e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI41425.1 - 0.00083 19.3 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_S49_N PF08496.10 KPI41425.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_S10 PF00450.22 KPI41427.1 - 2e-84 284.5 0.1 2.5e-84 284.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Tcp11 PF05794.13 KPI41428.1 - 8e-59 199.9 0.9 1.9e-48 165.7 0.8 2.0 2 0 0 2 2 2 2 T-complex protein 11 INCENP_ARK-bind PF03941.15 KPI41429.1 - 0.16 12.0 0.1 0.43 10.5 0.1 1.8 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region adh_short_C2 PF13561.6 KPI41430.1 - 1.2e-61 208.3 2.6 1.5e-61 207.9 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI41430.1 - 2.2e-49 167.6 2.4 3e-49 167.1 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KPI41430.1 - 1.9e-05 25.2 0.0 5.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KPI41430.1 - 6.4e-05 22.9 0.2 9.3e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.12 KPI41430.1 - 0.0053 17.4 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 KPI41430.1 - 0.054 13.4 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CW_7 PF08230.11 KPI41430.1 - 0.1 12.4 0.3 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 CW_7 repeat RIX1 PF08167.12 KPI41431.1 - 9.8e-28 97.2 2.7 1.1e-27 97.0 1.2 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Fungal_KA1 PF16797.5 KPI41432.1 - 3.5e-39 133.1 0.2 3.2e-37 126.9 0.0 2.1 2 0 0 2 2 2 2 Fungal kinase associated-1 domain TRAPPC9-Trs120 PF08626.11 KPI41433.1 - 1.1e-242 808.1 0.0 2e-231 770.8 0.0 2.0 1 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Pet127 PF08634.10 KPI41434.1 - 5e-110 367.3 1.6 1.2e-109 366.0 1.4 1.7 2 0 0 2 2 2 1 Mitochondrial protein Pet127 RNase_PH PF01138.21 KPI41435.1 - 2.1e-05 25.0 0.1 5.1e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Hexokinase_2 PF03727.16 KPI41436.1 - 1.1e-75 254.1 0.0 1.5e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KPI41436.1 - 3.9e-73 245.6 0.0 6e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Nup88 PF10168.9 KPI41437.1 - 0.039 11.8 1.8 0.053 11.3 1.8 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF3450 PF11932.8 KPI41437.1 - 0.62 9.3 6.0 0.33 10.2 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 KPI41437.1 - 4.6 7.9 10.4 53 4.5 0.0 3.2 2 1 1 3 3 3 0 SlyX Myosin_head PF00063.21 KPI41438.1 - 1.1e-60 205.6 0.1 2.1e-60 204.8 0.1 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KPI41438.1 - 1.7e-26 92.5 2.6 1.7e-26 92.5 2.6 2.5 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KPI41438.1 - 3.7e-15 54.2 28.8 0.00015 21.3 0.1 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif DegQ PF08181.11 KPI41438.1 - 0.063 13.4 0.8 0.34 11.0 0.8 2.4 1 0 0 1 1 1 0 DegQ (SacQ) family GAS PF13851.6 KPI41438.1 - 0.15 11.4 24.0 0.057 12.8 13.6 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 KPI41438.1 - 0.29 10.9 11.5 0.14 12.0 3.9 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Noelin-1 PF12308.8 KPI41438.1 - 0.71 9.9 3.3 3.6 7.6 3.3 2.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein Snapin_Pallidin PF14712.6 KPI41438.1 - 0.86 10.1 18.0 6.2 7.3 2.7 3.4 2 1 0 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 KPI41438.1 - 2.1 8.4 8.0 12 5.9 8.0 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad4 PF08650.10 KPI41438.1 - 3.4 7.7 5.7 6.2 6.9 0.6 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad4 Transcrip_reg PF01709.20 KPI41439.1 - 1.6e-62 211.0 3.7 4.1e-61 206.5 3.7 2.0 1 1 0 1 1 1 1 Transcriptional regulator IBN_N PF03810.19 KPI41440.1 - 0.0009 19.1 0.8 0.0009 19.1 0.8 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Importin_rep PF18773.1 KPI41440.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 KPI41440.1 - 0.037 14.1 0.2 0.44 10.6 0.0 2.8 3 0 0 3 3 3 0 Importin 13 repeat MHB PF16525.5 KPI41440.1 - 0.12 12.7 0.1 3.5 7.9 0.0 3.4 5 0 0 5 5 5 0 Haemophore, haem-binding CN_hydrolase PF00795.22 KPI41441.1 - 3.1e-17 62.8 0.1 1.2e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase M-inducer_phosp PF06617.13 KPI41442.1 - 0.049 12.9 1.0 0.055 12.7 1.0 1.0 1 0 0 1 1 1 0 M-phase inducer phosphatase DUF3235 PF11574.8 KPI41442.1 - 0.82 10.6 3.6 5 8.1 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) Amidohydro_3 PF07969.11 KPI41443.1 - 1.3e-58 199.6 0.2 1.6e-58 199.3 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KPI41443.1 - 2.7e-08 33.5 0.0 6.6e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Fcf2 PF08698.11 KPI41444.1 - 6e-35 119.5 0.2 6e-35 119.5 0.2 2.2 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing BORCS6 PF10157.9 KPI41445.1 - 9.6e-05 22.6 0.1 0.00019 21.7 0.1 1.5 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 6 HSBP1 PF06825.12 KPI41445.1 - 0.0067 16.3 3.7 1.5 8.7 0.2 2.3 2 0 0 2 2 2 2 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.11 KPI41445.1 - 0.019 15.5 3.0 0.032 14.8 2.2 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal AAA_13 PF13166.6 KPI41445.1 - 0.022 13.4 0.5 0.029 13.0 0.5 1.1 1 0 0 1 1 1 0 AAA domain Spore_III_AB PF09548.10 KPI41445.1 - 0.071 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Mating_N PF12731.7 KPI41445.1 - 0.083 13.0 0.9 16 5.7 0.1 2.6 3 0 0 3 3 3 0 Mating-type protein beta 1 CHIP_TPR_N PF18391.1 KPI41445.1 - 0.18 12.6 3.0 0.36 11.6 3.0 1.4 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain FadA PF09403.10 KPI41445.1 - 0.22 12.0 1.8 0.42 11.1 1.8 1.5 1 0 0 1 1 1 0 Adhesion protein FadA BLOC1_2 PF10046.9 KPI41445.1 - 1.2 9.5 3.8 0.69 10.2 1.6 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_12 PF01670.16 KPI41446.1 - 4.4e-16 59.5 4.9 3e-15 56.8 4.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Abhydrolase_6 PF12697.7 KPI41448.1 - 4.1e-13 50.5 0.0 5.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI41448.1 - 2.7e-12 46.9 0.0 1.4e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI41448.1 - 1e-08 34.8 0.1 1.9e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KPI41448.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KPI41448.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MRFAP1 PF15155.6 KPI41448.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 Acyl-CoA_dh_1 PF00441.24 KPI41450.1 - 9.9e-41 139.4 0.7 1.6e-40 138.8 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI41450.1 - 3.5e-29 100.9 0.2 6.3e-29 100.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI41450.1 - 6.2e-24 84.8 0.0 1.2e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPI41450.1 - 1.9e-12 47.6 0.1 2.8e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KPI41450.1 - 0.0001 22.1 0.2 0.00032 20.5 0.2 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF4208 PF13907.6 KPI41451.1 - 0.035 14.5 0.4 28 5.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) ApoLp-III PF07464.11 KPI41451.1 - 0.46 10.6 11.8 4.5 7.4 10.7 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) REF PF05755.12 KPI41451.1 - 3 7.6 6.3 2.5 7.9 1.6 2.2 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Cytochrom_C_2 PF01322.20 KPI41451.1 - 5.9 7.8 11.0 2 9.3 4.0 2.1 1 1 1 2 2 2 0 Cytochrome C' Lactamase_B PF00753.27 KPI41452.1 - 1.1e-05 25.5 0.5 0.11 12.5 0.7 2.7 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI41452.1 - 0.0071 15.9 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Flavodoxin_1 PF00258.25 KPI41453.1 - 2.2e-25 89.5 0.0 3.3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KPI41453.1 - 3.8e-19 69.2 0.0 1.2e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain GFO_IDH_MocA PF01408.22 KPI41454.1 - 2e-25 89.9 0.0 1.6e-24 87.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 KPI41454.1 - 0.062 13.5 0.3 0.28 11.3 0.3 1.9 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPI41454.1 - 0.078 13.6 0.1 0.42 11.2 0.0 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ras PF00071.22 KPI41456.1 - 3.2e-46 156.9 0.1 3.6e-46 156.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI41456.1 - 1.5e-15 57.5 0.0 2.1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI41456.1 - 1.7e-07 30.9 0.0 1.9e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI41456.1 - 3.3e-05 23.5 0.2 0.00026 20.6 0.1 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KPI41456.1 - 0.0001 21.8 0.1 0.00025 20.5 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPI41456.1 - 0.00043 20.4 0.0 0.0007 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI41456.1 - 0.0018 18.2 0.2 0.51 10.2 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GATase PF00117.28 KPI41457.1 - 2.1e-45 154.8 0.0 2.9e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KPI41457.1 - 3.4e-45 153.0 0.0 5.8e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KPI41457.1 - 0.00012 21.9 0.2 0.0017 18.1 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KPI41457.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Ipi1_N PF12333.8 KPI41458.1 - 1.1e-18 67.7 0.5 5.8e-18 65.4 0.0 2.2 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.20 KPI41458.1 - 0.0033 16.0 0.3 0.0045 15.6 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPI41458.1 - 0.012 15.7 0.6 0.039 14.0 0.4 1.9 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KPI41458.1 - 0.017 15.6 1.3 1.4 9.5 0.1 2.9 1 1 1 2 2 2 0 HEAT-like repeat CLASP_N PF12348.8 KPI41458.1 - 0.027 14.1 0.2 0.075 12.6 0.2 1.7 1 1 1 2 2 2 0 CLASP N terminal HEAT PF02985.22 KPI41458.1 - 0.044 14.0 1.1 3.7 8.1 0.2 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KPI41458.1 - 0.073 13.5 0.1 0.33 11.4 0.1 2.1 1 1 1 2 2 2 0 HEAT repeats RTP1_C1 PF10363.9 KPI41458.1 - 0.13 12.5 0.1 0.34 11.1 0.1 1.8 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Pex2_Pex12 PF04757.14 KPI41460.1 - 1.5e-36 126.1 8.5 1.9e-36 125.7 8.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KPI41460.1 - 8.4e-12 44.7 9.2 1.4e-11 44.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI41460.1 - 1.3e-11 44.6 9.4 2.3e-11 43.9 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KPI41460.1 - 4.3e-11 42.5 6.6 6.7e-11 41.9 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI41460.1 - 5.2e-10 39.0 7.3 9e-10 38.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI41460.1 - 2.1e-09 37.3 2.5 2.1e-09 37.3 2.5 1.8 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPI41460.1 - 2e-08 33.9 6.1 3.2e-08 33.3 6.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPI41460.1 - 1.4e-07 31.4 6.3 2.4e-07 30.6 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KPI41460.1 - 4.3e-06 26.9 7.4 8.3e-06 26.0 7.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KPI41460.1 - 8.3e-05 22.7 8.9 0.00015 21.8 8.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KPI41460.1 - 0.0081 16.2 2.5 0.015 15.3 2.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KPI41460.1 - 0.011 15.6 1.9 0.021 14.7 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KPI41460.1 - 0.036 14.2 6.4 0.072 13.2 6.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KPI41460.1 - 0.12 12.2 4.1 0.24 11.3 4.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KPI41460.1 - 0.71 9.7 9.8 1.6 8.6 9.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KPI41460.1 - 5.4 6.9 6.5 1.7 8.4 2.9 2.0 2 0 0 2 2 2 0 RING-like zinc finger CorA PF01544.18 KPI41463.1 - 1.7e-39 135.9 0.0 2.2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_1 PF00561.20 KPI41464.1 - 3.8e-22 79.2 0.0 4.9e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI41464.1 - 1.1e-13 52.4 0.7 1.3e-13 52.0 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI41464.1 - 1.6e-06 27.6 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF1057 PF06342.12 KPI41464.1 - 0.0022 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 KPI41464.1 - 0.0031 16.5 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KPI41464.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 KPI41464.1 - 0.11 12.1 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) BTB PF00651.31 KPI41465.1 - 1.5e-22 79.9 0.0 2e-11 44.1 0.5 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KPI41465.1 - 7.6e-08 32.7 0.0 2.4e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI41465.1 - 1.7e-06 28.5 0.0 3.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI41465.1 - 4.5e-05 23.6 0.0 0.00018 21.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KPI41465.1 - 0.00022 21.5 0.1 0.025 15.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 KPI41465.1 - 0.0016 18.6 0.1 0.0049 17.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Ank_3 PF13606.6 KPI41465.1 - 0.03 14.8 1.6 0.48 11.1 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat Imm68 PF15583.6 KPI41465.1 - 0.033 14.4 0.3 0.15 12.2 0.3 2.1 1 1 0 1 1 1 0 Immunity protein 68 DIOX_N PF14226.6 KPI41466.1 - 2.2e-30 105.8 0.0 3.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI41466.1 - 1.7e-17 63.7 0.0 3.6e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_4 PF12799.7 KPI41467.1 - 0.053 14.0 0.1 55 4.4 0.0 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_L28e PF01778.17 KPI41468.1 - 4.4e-35 120.9 0.3 1e-34 119.7 0.3 1.6 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KPI41468.1 - 4.4e-27 94.6 17.4 4.4e-27 94.6 17.4 2.3 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KPI41468.1 - 7.7e-06 25.5 15.6 9.2e-06 25.2 15.6 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KPI41468.1 - 0.032 14.0 1.4 0.047 13.4 0.5 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Proteasom_Rpn13 PF04683.13 KPI41468.1 - 0.087 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Cwf_Cwc_15 PF04889.12 KPI41468.1 - 0.25 11.0 17.8 0.38 10.4 17.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KPI41468.1 - 0.34 9.1 24.6 0.44 8.7 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 KPI41468.1 - 2.4 7.8 12.4 3.8 7.1 12.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TFIIF_alpha PF05793.12 KPI41468.1 - 9.7 4.7 25.4 16 3.9 25.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 KPI41470.1 - 2.1e-67 227.3 0.7 2.3e-66 223.9 0.7 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41470.1 - 8.6e-51 172.7 0.0 1.7e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KPI41470.1 - 3.5e-24 84.9 0.3 3.3e-23 81.8 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 KPI41470.1 - 4.1e-06 26.3 0.0 6.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPI41470.1 - 4.2e-05 22.5 0.0 4.2e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KPI41470.1 - 7.3e-05 21.9 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 KPI41470.1 - 0.0016 18.9 0.0 0.0064 16.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Seadorna_VP7 PF07387.11 KPI41470.1 - 0.011 14.8 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KPI41470.1 - 0.32 10.9 3.8 0.58 10.0 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 KPI41471.1 - 1.1e-44 152.9 0.0 7.6e-43 146.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TatD_DNase PF01026.21 KPI41472.1 - 8.5e-51 172.8 0.0 9.8e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase ABC_tran PF00005.27 KPI41474.1 - 2.8e-16 60.3 0.2 2.4e-09 37.8 0.1 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KPI41474.1 - 3.6e-12 46.7 2.9 3.5e-06 27.0 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI41474.1 - 0.0012 18.3 0.1 0.47 9.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI41474.1 - 0.0027 17.4 0.6 0.0061 16.3 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KPI41474.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.8 KPI41474.1 - 0.0077 13.8 0.3 0.011 13.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.6 KPI41474.1 - 0.01 15.5 1.2 0.028 14.0 1.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KPI41474.1 - 0.011 16.2 0.4 0.02 15.4 0.4 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KPI41474.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KPI41474.1 - 0.018 14.9 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 KPI41474.1 - 0.022 14.5 0.2 0.033 13.9 0.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 KPI41474.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KPI41474.1 - 0.068 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain POTRA_3 PF17287.2 KPI41474.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 POTRA domain AAA_13 PF13166.6 KPI41474.1 - 0.074 11.7 0.1 0.098 11.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KPI41474.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KPI41474.1 - 0.11 12.3 0.2 0.49 10.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KPI41474.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 KPI41474.1 - 0.18 11.8 0.5 1.6 8.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arf PF00025.21 KPI41474.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 KPI41474.1 - 0.21 11.9 1.7 0.57 10.5 0.9 2.1 2 1 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 KPI41474.1 - 0.22 11.6 0.1 0.42 10.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KPI41474.1 - 0.23 11.0 0.2 0.36 10.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 KPI41475.1 - 1.3e-54 185.4 0.2 1.3e-54 185.4 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41475.1 - 1.5e-35 122.7 0.0 2.4e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KPI41475.1 - 0.0068 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PrkA PF06798.12 KPI41475.1 - 0.0084 15.8 4.9 0.014 15.1 4.9 1.2 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain Pkinase_fungal PF17667.1 KPI41475.1 - 0.095 11.5 0.8 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Bul1_C PF04426.12 KPI41475.1 - 0.17 11.3 0.4 0.3 10.5 0.4 1.4 1 0 0 1 1 1 0 Bul1 C terminus APH PF01636.23 KPI41475.1 - 0.17 11.8 1.3 3.2 7.6 0.0 2.8 2 1 0 3 3 3 0 Phosphotransferase enzyme family LETM1 PF07766.13 KPI41479.1 - 4.7e-106 354.0 0.7 4.7e-106 354.0 0.7 1.8 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KPI41479.1 - 0.00029 20.5 0.0 0.0034 17.1 0.0 2.6 2 0 0 2 2 2 1 SAP domain DDOST_48kD PF03345.14 KPI41480.1 - 1.1e-150 502.1 0.0 1.3e-150 501.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Cyclin_N PF00134.23 KPI41481.1 - 0.0023 17.7 0.1 0.03 14.1 0.0 2.5 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KPI41481.1 - 0.17 12.0 0.2 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Acetyltransf_1 PF00583.25 KPI41482.1 - 7.2e-08 32.7 0.0 1.5e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI41482.1 - 2.3e-05 24.7 0.0 5e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI41482.1 - 0.00022 21.1 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPI41482.1 - 0.00041 20.3 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1656 PF07869.12 KPI41483.1 - 0.039 14.0 0.3 0.059 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) His_biosynth PF00977.21 KPI41484.1 - 3e-36 125.0 0.0 3.6e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KPI41484.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 KPI41484.1 - 0.059 12.7 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase ADH_N PF08240.12 KPI41485.1 - 2.3e-28 98.3 0.7 4.7e-28 97.2 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI41485.1 - 4.6e-10 39.6 1.0 4.2e-08 33.2 0.2 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KPI41485.1 - 5.2e-10 39.1 1.3 5.2e-10 39.1 1.3 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 KPI41485.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 KPI41485.1 - 0.12 12.4 1.6 0.45 10.6 0.8 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region AlaDh_PNT_C PF01262.21 KPI41485.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_1_2 PF00155.21 KPI41486.1 - 9.4e-86 288.2 0.0 1.2e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPI41486.1 - 3.1e-06 26.0 0.0 5.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KPI41486.1 - 3.9e-05 22.8 0.0 7.2e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPI41486.1 - 0.00011 21.7 0.1 0.00027 20.4 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KPI41486.1 - 0.004 16.5 0.1 0.0098 15.2 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.10 KPI41486.1 - 0.078 13.5 1.4 0.46 11.0 1.3 2.1 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence AA_permease_2 PF13520.6 KPI41489.1 - 4.5e-44 150.9 46.1 5.6e-44 150.6 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI41489.1 - 5.3e-15 55.0 38.8 7.2e-15 54.5 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease GWT1 PF06423.12 KPI41489.1 - 0.13 12.4 4.5 44 4.2 4.4 2.8 1 1 0 1 1 1 0 GWT1 PMP1_2 PF08114.11 KPI41489.1 - 0.4 10.4 0.1 0.4 10.4 0.1 2.9 4 0 0 4 4 4 0 ATPase proteolipid family adh_short PF00106.25 KPI41490.1 - 3.1e-17 62.7 0.0 6.8e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41490.1 - 4.2e-14 52.7 0.1 8e-14 51.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41490.1 - 5.8e-07 29.6 0.1 8.2e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI41490.1 - 0.00012 21.6 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI41490.1 - 0.0018 17.8 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 KPI41491.1 - 3.2e-06 26.9 0.1 8.5e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI41491.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.18 KPI41492.1 - 1.7e-24 86.3 0.1 2.5e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.23 KPI41493.1 - 1.1e-65 221.7 0.1 1.5e-65 221.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KPI41493.1 - 1.6e-14 53.5 0.0 3.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.6 KPI41493.1 - 9.5e-10 38.2 10.0 9.5e-10 38.2 10.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI41493.1 - 1.5e-09 37.5 11.8 4.3e-09 36.1 11.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KPI41493.1 - 8.7e-08 32.5 0.0 4.2e-07 30.3 0.0 2.2 2 1 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KPI41493.1 - 2.2e-07 31.1 13.9 2.3e-07 31.0 11.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI41493.1 - 4.3e-07 29.8 7.9 1.3e-06 28.3 7.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPI41493.1 - 5.4e-07 29.5 10.4 1.2e-06 28.4 10.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPI41493.1 - 2.7e-06 27.1 12.3 2.7e-06 27.1 12.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KPI41493.1 - 3.6e-06 27.2 7.3 1.7e-05 25.0 7.0 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KPI41493.1 - 6.1e-06 26.3 11.7 1.4e-05 25.1 11.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 KPI41493.1 - 0.001 19.2 0.1 0.0044 17.2 0.1 2.1 1 0 0 1 1 1 1 U-box domain zf-P11 PF03854.14 KPI41493.1 - 0.0018 17.9 3.4 0.0018 17.9 3.4 2.1 2 0 0 2 2 2 1 P-11 zinc finger Prok-RING_4 PF14447.6 KPI41493.1 - 0.0047 16.8 9.2 0.013 15.4 9.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KPI41493.1 - 0.0062 16.6 2.2 0.015 15.3 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KPI41493.1 - 0.011 15.6 3.2 0.027 14.3 3.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KPI41493.1 - 0.015 15.1 7.5 0.054 13.3 6.8 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KPI41493.1 - 0.24 11.6 7.5 0.72 10.0 7.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 KPI41493.1 - 0.32 11.1 5.3 0.94 9.6 5.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KPI41493.1 - 0.56 10.0 4.1 2 8.2 4.1 2.1 1 0 0 1 1 1 0 RING-like zinc finger SAPIS-gp6 PF16722.5 KPI41493.1 - 3 8.3 6.0 1.2 9.6 1.7 2.3 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus CorA PF01544.18 KPI41495.1 - 1.8e-10 40.7 4.0 1.3e-08 34.5 0.0 2.5 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein Kinesin_assoc PF16183.5 KPI41495.1 - 0.0021 18.2 0.8 0.0039 17.3 0.8 1.4 1 0 0 1 1 1 1 Kinesin-associated CAP_N PF01213.19 KPI41495.1 - 0.079 12.4 3.4 0.45 9.9 0.6 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Fib_alpha PF08702.10 KPI41495.1 - 0.1 12.7 1.6 0.26 11.5 1.6 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ApoL PF05461.11 KPI41495.1 - 0.91 8.8 10.5 1.7 7.9 1.2 2.4 1 1 1 2 2 2 0 Apolipoprotein L HABP4_PAI-RBP1 PF04774.15 KPI41495.1 - 2.4 9.0 5.1 0.93 10.4 1.8 1.9 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Abhydrolase_6 PF12697.7 KPI41496.1 - 8.7e-07 29.8 0.5 1.6e-06 28.9 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI41496.1 - 0.00056 19.3 0.0 0.0068 15.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI41496.1 - 0.0015 18.2 0.0 0.011 15.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KPI41496.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase WD40 PF00400.32 KPI41497.1 - 3.7e-13 49.7 12.9 0.17 12.8 0.1 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI41497.1 - 1.8e-05 25.0 0.0 0.74 10.2 0.1 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Staph_haemo PF05480.11 KPI41497.1 - 0.051 13.4 2.5 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 Staphylococcus haemolytic protein Malate_synthase PF01274.22 KPI41498.1 - 1e-227 756.6 0.0 1.3e-227 756.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Ribosomal_S30 PF04758.14 KPI41501.1 - 1.4e-29 102.1 8.5 1.5e-29 102.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 adh_short PF00106.25 KPI41502.1 - 1.2e-20 73.8 0.0 2.2e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41502.1 - 3e-11 43.3 0.0 2e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41502.1 - 5.7e-05 23.1 0.0 0.00015 21.8 0.0 1.6 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 KPI41502.1 - 0.2 11.0 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 KPI41502.1 - 0.21 11.4 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Acetyltransf_7 PF13508.7 KPI41503.1 - 5.8e-05 23.4 0.1 0.00012 22.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI41503.1 - 0.0003 20.7 0.1 0.00098 19.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI41503.1 - 0.00062 20.0 0.2 0.0011 19.2 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Redoxin PF08534.10 KPI41504.1 - 3.7e-35 120.8 0.0 4.2e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KPI41504.1 - 1.7e-10 40.9 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DEAD PF00270.29 KPI41507.1 - 5.9e-16 58.7 0.1 8.7e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI41507.1 - 2.7e-13 50.2 0.0 2.1e-11 44.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KPI41507.1 - 2.5e-09 37.7 2.3 7.6e-09 36.2 2.3 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Mito_carr PF00153.27 KPI41508.1 - 2.6e-50 168.3 0.4 4.8e-16 58.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein bVLRF1 PF18826.1 KPI41509.1 - 1.3e-60 203.6 0.1 1.3e-60 203.6 0.1 2.1 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KPI41509.1 - 7.3e-06 26.2 0.1 1.7e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KPI41509.1 - 0.00031 21.1 0.4 0.00074 19.9 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KPI41509.1 - 0.022 15.3 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.7 KPI41509.1 - 0.092 13.1 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPI41509.1 - 0.18 12.7 0.5 0.41 11.6 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI41509.1 - 0.19 12.0 1.3 0.36 11.2 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ank_3 PF13606.6 KPI41509.1 - 0.2 12.3 0.0 0.65 10.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat NAD_binding_2 PF03446.15 KPI41510.1 - 9e-14 51.9 0.0 1.1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.15 KPI41510.1 - 0.00016 20.8 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KPI41510.1 - 0.0017 18.9 0.1 0.0028 18.2 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SSP160 PF06933.11 KPI41510.1 - 0.012 13.9 0.1 0.012 13.9 0.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NAD_Gly3P_dh_N PF01210.23 KPI41510.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KPI41510.1 - 0.055 13.7 0.0 0.3 11.3 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Nucleo_P87 PF07267.11 KPI41511.1 - 0.16 10.8 4.6 0.18 10.6 4.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-Tim10_DDP PF02953.15 KPI41512.1 - 2.3e-21 75.2 2.7 2.9e-21 74.9 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3336 PF11815.8 KPI41512.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) FAD_binding_4 PF01565.23 KPI41513.1 - 8e-14 51.6 2.9 1.6e-13 50.6 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain IMP2_C PF18591.1 KPI41513.1 - 0.15 12.0 0.1 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Wbp11 PF09429.10 KPI41514.1 - 8.5e-22 77.4 19.4 8.5e-22 77.4 19.4 2.4 2 1 0 2 2 2 1 WW domain binding protein 11 Peptidase_S49_N PF08496.10 KPI41514.1 - 9.6 6.2 7.9 21 5.2 7.9 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAD_binding_3 PF01494.19 KPI41516.1 - 1.5e-09 37.6 0.0 3.1e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI41516.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI41516.1 - 0.042 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.6 KPI41517.1 - 1.6e-15 57.5 0.0 1.7e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Laminin_G_3 PF13385.6 KPI41518.1 - 4.3e-10 39.9 0.0 7.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 KPI41518.1 - 9.6e-06 25.0 0.7 0.0003 20.1 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) CRAL_TRIO PF00650.20 KPI41519.1 - 4.2e-23 81.8 0.0 8.4e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPI41519.1 - 5.5e-09 36.1 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Pept_tRNA_hydro PF01195.19 KPI41520.1 - 4.6e-27 95.0 0.0 1.2e-26 93.7 0.0 1.6 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Aldedh PF00171.22 KPI41522.1 - 9.6e-147 489.2 0.0 1.2e-146 488.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AdoMet_MTase PF07757.13 KPI41523.1 - 2.7e-33 114.7 0.0 5.4e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KPI41523.1 - 0.035 14.1 0.0 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Cyclin_C_2 PF16899.5 KPI41525.1 - 3.6e-28 98.0 0.0 3.9e-25 88.3 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KPI41525.1 - 1.5e-06 28.0 0.0 4.4e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Abhydrolase_1 PF00561.20 KPI41526.1 - 1.6e-18 67.3 0.0 4.7e-18 65.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI41526.1 - 2e-15 58.0 0.0 3.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI41526.1 - 4.6e-11 42.4 0.0 7.5e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPI41526.1 - 2.4e-07 31.1 0.0 4.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KPI41526.1 - 8.5e-05 22.4 0.1 0.07 12.8 0.1 2.1 1 1 1 2 2 2 2 PGAP1-like protein Esterase PF00756.20 KPI41526.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.16 KPI41526.1 - 0.038 13.6 0.1 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Chlorophyllase2 PF12740.7 KPI41526.1 - 0.055 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KPI41526.1 - 0.15 11.9 0.1 0.82 9.4 0.0 1.9 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 KPI41526.1 - 0.19 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioredoxin PF00085.20 KPI41527.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KPI41527.1 - 0.09 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Fungal_trans PF04082.18 KPI41528.1 - 4.2e-23 81.7 0.7 5.3e-23 81.4 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_kinase PF00696.28 KPI41529.1 - 9.4e-44 149.8 0.2 1.5e-43 149.2 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KPI41529.1 - 5.5e-13 48.5 0.8 4.6e-11 42.3 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KPI41529.1 - 2.4e-10 40.0 0.1 5.9e-09 35.5 0.0 2.8 2 0 0 2 2 2 1 ACT domain ASH PF15780.5 KPI41529.1 - 0.077 13.2 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PhoLip_ATPase_C PF16212.5 KPI41530.1 - 2.5e-50 171.5 1.0 3.4e-50 171.1 1.0 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KPI41530.1 - 3.1e-09 37.4 0.0 0.00046 20.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPI41530.1 - 0.0035 17.1 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2070 PF09843.9 KPI41530.1 - 0.41 8.9 4.9 0.56 8.4 4.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SPC12 PF06645.13 KPI41531.1 - 2.4e-25 88.4 0.4 2.8e-25 88.2 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Pex24p PF06398.11 KPI41531.1 - 0.16 10.9 0.0 0.18 10.8 0.0 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF1682 PF07946.14 KPI41532.1 - 2.3 7.4 10.3 2.4 7.3 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_L23eN PF03939.13 KPI41533.1 - 7.6e-23 80.5 10.4 7.6e-23 80.5 10.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KPI41533.1 - 2.3e-15 56.7 0.6 2.3e-15 56.7 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 Pet100 PF09803.9 KPI41534.1 - 2.5e-18 66.3 0.1 3.5e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Pet100 MscS_porin PF12795.7 KPI41535.1 - 1.9 8.0 9.1 0.16 11.5 3.4 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain AA_permease_2 PF13520.6 KPI41536.1 - 1.2e-90 304.4 39.8 1.6e-90 304.0 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI41536.1 - 3.9e-19 68.6 34.9 5.6e-19 68.1 34.9 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KPI41537.1 - 9.9e-39 132.8 0.1 1.4e-38 132.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41537.1 - 3.6e-30 105.3 0.0 5.4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41537.1 - 0.016 15.2 0.4 0.091 12.7 0.4 2.1 2 1 0 2 2 2 0 KR domain MitMem_reg PF13012.6 KPI41538.1 - 8.1e-18 64.9 0.2 1.5e-17 64.0 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KPI41538.1 - 2.2e-16 59.9 0.0 3.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KPI41538.1 - 0.00032 20.8 0.0 0.00094 19.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) Fasciclin PF02469.22 KPI41541.1 - 1.8e-43 147.8 0.0 1.3e-23 83.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Clusterin PF01093.17 KPI41541.1 - 0.29 10.1 0.1 0.46 9.5 0.1 1.2 1 0 0 1 1 1 0 Clusterin Fungal_trans PF04082.18 KPI41542.1 - 4e-22 78.5 0.0 1e-21 77.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI41542.1 - 5.2e-09 36.1 13.8 9e-09 35.3 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_90 PF05686.12 KPI41543.1 - 1.9e-31 109.4 3.0 3.2e-31 108.6 3.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KPI41543.1 - 0.0052 17.1 0.6 0.024 15.0 0.5 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Vps55 PF04133.14 KPI41544.1 - 6.2e-39 132.6 2.1 7e-39 132.4 2.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Peptidase_A24 PF01478.18 KPI41544.1 - 0.068 13.6 5.3 0.7 10.3 0.4 2.1 2 0 0 2 2 2 0 Type IV leader peptidase family GAS2 PF02187.17 KPI41545.1 - 3.1e-06 27.2 0.1 6.3e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Abhydrolase_6 PF12697.7 KPI41546.1 - 1.6e-14 55.0 2.2 5.8e-13 49.9 0.5 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI41546.1 - 4.6e-14 52.7 0.0 1.4e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI41546.1 - 0.00073 18.9 0.0 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 NAD_binding_1 PF00175.21 KPI41547.1 - 3.7e-08 34.0 0.0 5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Y_phosphatase2 PF03162.13 KPI41548.1 - 1.7e-41 141.6 0.0 2.5e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KPI41548.1 - 2.5e-10 40.7 0.0 4.9e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KPI41548.1 - 2.7e-05 24.0 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPI41548.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 KPI41548.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-rbx1 PF12678.7 KPI41549.1 - 5e-25 87.6 12.7 7.1e-25 87.1 12.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI41549.1 - 2.5e-17 62.7 10.3 3.3e-17 62.3 10.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KPI41549.1 - 5.9e-06 26.5 15.1 0.00019 21.7 15.1 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI41549.1 - 7.9e-05 22.4 3.4 7.9e-05 22.4 3.4 2.3 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI41549.1 - 0.0017 18.2 11.6 0.024 14.5 11.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KPI41549.1 - 0.11 12.6 8.3 0.49 10.6 8.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KPI41549.1 - 0.34 10.8 10.6 0.76 9.7 4.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI41549.1 - 0.39 10.8 7.3 1.3 9.1 7.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KPI41549.1 - 0.54 9.9 14.7 0.13 11.9 4.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KPI41549.1 - 1.1 9.0 17.0 93 2.9 17.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger Glycos_transf_1 PF00534.20 KPI41550.1 - 6.6e-18 64.8 0.0 1.8e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPI41550.1 - 5.5e-14 52.7 0.0 1.7e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KPI41550.1 - 0.00096 19.5 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cas_Cas2CT1978 PF09707.10 KPI41550.1 - 0.1 12.7 0.0 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) ThuA PF06283.11 KPI41550.1 - 0.16 12.2 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Trehalose utilisation IBN_N PF03810.19 KPI41551.1 - 0.066 13.1 0.1 3.7 7.5 0.0 2.6 2 1 0 2 2 2 0 Importin-beta N-terminal domain UBA PF00627.31 KPI41552.1 - 2.5e-25 88.0 0.9 7.3e-12 45.0 0.3 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KPI41552.1 - 2.8e-22 78.2 18.6 4.8e-22 77.5 18.6 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KPI41552.1 - 6.8e-21 73.8 0.0 1.2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPI41552.1 - 2.2e-06 27.4 0.1 3.5e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KPI41552.1 - 0.0002 21.1 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KPI41552.1 - 0.0065 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPI41552.1 - 0.025 15.2 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 KPI41552.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 CUE domain Ubiquitin_5 PF18037.1 KPI41552.1 - 0.18 12.2 0.1 0.32 11.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KPI41552.1 - 0.22 12.0 0.0 0.52 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain FAP PF07174.11 KPI41552.1 - 0.63 9.4 33.9 0.13 11.7 25.8 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) SOG2 PF10428.9 KPI41552.1 - 0.71 9.0 3.5 0.75 8.9 3.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HAD_2 PF13419.6 KPI41554.1 - 5.1e-12 46.2 0.0 8.9e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI41554.1 - 6.3e-07 29.9 0.0 1e-06 29.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI41554.1 - 0.00076 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TFA2_Winged_2 PF18121.1 KPI41554.1 - 0.032 13.9 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Hydrolase_6 PF13344.6 KPI41554.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Myosin_head PF00063.21 KPI41555.1 - 8.4e-183 609.2 4.6 1e-182 608.9 4.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KPI41555.1 - 0.0024 18.3 0.0 0.0059 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 KPI41555.1 - 0.0032 16.9 1.2 1.8 8.0 0.1 3.9 2 2 1 3 3 3 1 PhoH-like protein NACHT PF05729.12 KPI41555.1 - 0.0034 17.3 0.3 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KPI41555.1 - 0.0061 16.8 0.3 0.034 14.4 0.2 2.4 1 1 1 2 2 2 1 AAA domain Myosin_N PF02736.19 KPI41555.1 - 0.01 15.7 0.4 0.036 13.9 0.0 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain T2SSE PF00437.20 KPI41555.1 - 0.012 14.7 0.0 0.077 12.0 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.7 KPI41555.1 - 0.041 12.8 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.26 KPI41555.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KPI41555.1 - 0.054 14.0 0.3 0.12 12.8 0.2 1.8 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KPI41555.1 - 0.1 13.0 0.1 0.65 10.4 0.0 2.3 3 0 0 3 3 2 0 RNA helicase AAA PF00004.29 KPI41555.1 - 0.1 13.0 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KPI41555.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 KPI41556.1 - 1.5e-21 76.3 25.0 7.1e-05 23.5 0.3 11.1 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI41556.1 - 3.3e-07 30.5 4.7 0.078 13.3 0.1 6.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF89 PF01937.19 KPI41558.1 - 1e-124 416.1 0.0 1.2e-124 415.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CMAS PF02353.20 KPI41559.1 - 6.8e-38 130.5 0.2 8.5e-38 130.2 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KPI41559.1 - 6.1e-17 62.1 0.0 1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI41559.1 - 9.2e-17 61.5 0.0 1.5e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI41559.1 - 3e-16 59.6 0.0 4.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI41559.1 - 2.5e-13 50.2 0.0 3.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI41559.1 - 1.1e-11 45.3 0.0 1.7e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI41559.1 - 2e-09 37.2 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KPI41559.1 - 6.9e-07 28.9 0.0 2.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KPI41559.1 - 5.6e-05 22.5 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 KPI41559.1 - 0.00014 21.0 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 KPI41559.1 - 0.0002 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 KPI41559.1 - 0.00038 19.9 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KPI41559.1 - 0.0014 18.7 0.0 0.004 17.3 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 KPI41559.1 - 0.0023 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MetW PF07021.12 KPI41559.1 - 0.005 16.5 0.0 0.0086 15.7 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 KPI41559.1 - 0.0051 16.3 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KPI41559.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 KPI41559.1 - 0.022 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 KPI41559.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KPI41559.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DNA_methylase PF00145.17 KPI41560.1 - 3.4e-40 138.4 0.0 1.7e-28 100.0 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_25 PF13649.6 KPI41560.1 - 0.14 12.9 0.0 0.69 10.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_M24 PF00557.24 KPI41562.1 - 1.2e-42 146.0 0.0 1.8e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KPI41562.1 - 9.4e-42 142.8 3.6 2.2e-39 135.1 0.4 3.5 3 1 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KPI41562.1 - 4.4e-23 81.1 0.4 1.3e-22 79.7 0.4 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KPI41562.1 - 2.3e-18 67.1 0.0 1.5e-17 64.5 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Lysine_decarbox PF03641.14 KPI41563.1 - 6.1e-31 107.2 0.0 1.2e-30 106.3 0.0 1.5 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KPI41563.1 - 4.5e-06 26.3 0.3 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 1 SLOG cluster4 family DAGK_cat PF00781.24 KPI41563.1 - 0.017 14.8 0.5 1.6 8.4 0.0 2.7 3 1 0 3 3 3 0 Diacylglycerol kinase catalytic domain p450 PF00067.22 KPI41564.1 - 8.1e-51 173.2 0.0 1.1e-50 172.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_17 PF00332.18 KPI41565.1 - 3.7e-09 36.6 4.2 8.4e-07 28.9 1.5 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 AAA_12 PF13087.6 KPI41566.1 - 5.9e-35 120.7 0.0 9.5e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KPI41566.1 - 3.4e-18 66.4 3.0 5.4e-18 65.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KPI41566.1 - 1e-08 35.1 0.0 1.9e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KPI41566.1 - 4.3e-08 33.6 0.0 5.3e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KPI41566.1 - 6.6e-07 29.3 0.0 0.0014 18.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KPI41566.1 - 0.0024 17.4 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KPI41566.1 - 0.014 14.7 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KPI41566.1 - 0.024 14.7 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI41566.1 - 0.032 14.0 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KPI41566.1 - 0.033 14.2 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A51 PF04948.13 KPI41566.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein AAA PF00004.29 KPI41566.1 - 0.23 11.9 0.5 1.7 9.0 0.2 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UBA PF00627.31 KPI41567.1 - 0.013 15.4 0.1 0.056 13.4 0.1 2.1 1 0 0 1 1 1 0 UBA/TS-N domain XhlA PF10779.9 KPI41568.1 - 0.03 14.5 1.3 0.03 14.5 1.3 3.2 3 1 2 5 5 5 0 Haemolysin XhlA DUF3450 PF11932.8 KPI41568.1 - 0.038 13.3 0.4 0.038 13.3 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KPI41568.1 - 0.15 12.1 25.9 1 9.4 15.6 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 KPI41568.1 - 0.21 11.6 33.9 0.23 11.5 22.2 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KPI41568.1 - 0.76 8.8 17.5 0.54 9.3 13.9 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 KPI41568.1 - 0.88 9.1 23.6 0.56 9.7 1.7 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Occludin_ELL PF07303.13 KPI41568.1 - 2.2 9.1 15.1 0.12 13.1 7.9 2.4 2 1 1 3 3 3 0 Occludin homology domain Fez1 PF06818.15 KPI41568.1 - 9.4 6.6 26.8 9 6.7 19.8 2.1 2 0 0 2 2 2 0 Fez1 Proteasome PF00227.26 KPI41569.1 - 6.9e-50 169.2 0.1 8.7e-50 168.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPI41569.1 - 4.9e-12 45.3 0.3 4.9e-12 45.3 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DER1 PF04511.15 KPI41570.1 - 5.7e-18 65.5 4.9 2.9e-17 63.2 2.7 2.0 1 1 1 2 2 2 1 Der1-like family Peptidase_U4 PF03419.13 KPI41570.1 - 0.34 10.2 2.7 0.37 10.0 1.8 1.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA BTB PF00651.31 KPI41571.1 - 4.1e-06 27.0 0.0 6.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sugar_tr PF00083.24 KPI41572.1 - 9.1e-88 295.1 25.0 1.1e-87 294.8 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41572.1 - 1.9e-16 60.0 29.6 3e-16 59.3 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KPI41572.1 - 0.31 11.3 8.0 0.6 10.4 2.2 3.8 3 0 0 3 3 3 0 Transglycosylase associated protein PDR_assoc PF08370.11 KPI41572.1 - 0.37 10.6 5.9 0.11 12.2 1.7 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Gly_transf_sug PF04488.15 KPI41573.1 - 7e-19 68.3 0.0 1.6e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KPI41573.1 - 0.69 9.1 1.4 0.68 9.2 0.3 1.4 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain SNase PF00565.17 KPI41576.1 - 7.1e-75 248.4 2.7 7.3e-22 77.9 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KPI41576.1 - 2.2e-24 85.8 0.0 3.8e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KPI41576.1 - 5.8e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KPI41576.1 - 0.002 18.5 0.1 0.0086 16.5 0.1 2.1 1 0 0 1 1 1 1 Agenet domain zf-C2HC5 PF06221.13 KPI41577.1 - 2.7e-21 75.3 6.1 4.3e-21 74.7 6.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ECH_1 PF00378.20 KPI41578.1 - 3.9e-27 95.2 0.0 6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI41578.1 - 7.8e-19 68.3 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Transp_cyt_pur PF02133.15 KPI41579.1 - 4.7e-82 276.1 31.2 5.4e-82 275.9 31.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FMO-like PF00743.19 KPI41581.1 - 9.9e-22 77.0 1.1 1.8e-16 59.7 0.1 3.0 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI41581.1 - 2.1e-20 73.2 0.0 1.4e-19 70.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI41581.1 - 5.5e-14 52.1 0.0 4e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI41581.1 - 2.7e-07 30.7 0.0 0.0012 19.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI41581.1 - 2.7e-07 31.0 0.2 0.1 13.2 0.0 3.5 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI41581.1 - 7.6e-07 28.6 0.5 9.2e-05 21.7 0.0 2.9 2 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KPI41581.1 - 7.1e-06 25.5 0.2 0.032 13.5 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 KPI41581.1 - 9.4e-06 25.2 0.0 0.23 10.8 0.0 3.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI41581.1 - 0.0002 21.4 2.5 0.25 11.3 0.1 3.5 3 1 1 4 4 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KPI41581.1 - 0.00031 20.2 0.0 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KPI41581.1 - 0.00071 18.8 0.0 0.11 11.5 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 KPI41581.1 - 0.00078 19.1 0.6 0.12 11.9 0.2 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI41581.1 - 0.0012 18.0 1.1 0.038 13.1 0.2 2.8 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KPI41581.1 - 0.0015 17.3 0.0 0.045 12.5 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KPI41581.1 - 0.0015 17.7 0.1 0.045 12.8 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 KPI41581.1 - 0.019 14.2 0.0 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KPI41581.1 - 0.023 14.0 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 KPI41581.1 - 0.085 13.4 0.0 0.53 10.9 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KPI41581.1 - 0.17 11.7 0.0 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UQ_con PF00179.26 KPI41582.1 - 9.9e-42 141.9 0.0 1.2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KPI41582.1 - 6e-06 26.0 0.0 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KPI41582.1 - 0.00081 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.31 KPI41582.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF1421 PF07223.11 KPI41582.1 - 0.02 14.7 0.3 0.049 13.5 0.3 1.6 1 0 0 1 1 1 0 UBA-like domain (DUF1421) RWD PF05773.22 KPI41582.1 - 0.021 15.1 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Glyco_transf_34 PF05637.12 KPI41583.1 - 1.8e-11 44.2 0.2 2.5e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family SVM_signal PF12113.8 KPI41583.1 - 0.14 12.0 2.7 0.28 11.1 2.7 1.4 1 0 0 1 1 1 0 SVM protein signal sequence PBP1_TM PF14812.6 KPI41584.1 - 0.032 14.6 1.8 0.032 14.6 1.8 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1687 PF07955.11 KPI41585.1 - 1.1e-29 103.5 0.1 1.5e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 KPI41585.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 ArsC family LPD38 PF18857.1 KPI41585.1 - 0.03 14.5 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 PIG-X PF08320.12 KPI41586.1 - 3.7e-52 177.3 0.8 6.9e-52 176.4 0.8 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 His_Phos_1 PF00300.22 KPI41587.1 - 3.1e-19 69.4 0.0 1.1e-18 67.7 0.0 1.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) UCR_Fe-S_N PF10399.9 KPI41587.1 - 0.0081 15.5 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal adh_short PF00106.25 KPI41588.1 - 9.8e-24 83.9 0.0 6.4e-18 64.9 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41588.1 - 1.1e-13 51.3 0.0 9e-11 41.8 0.0 2.5 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41588.1 - 6.1e-06 26.3 0.0 1.5e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Ribosomal_S3Ae PF01015.18 KPI41589.1 - 4e-90 300.8 1.7 4.7e-90 300.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KPI41589.1 - 0.022 15.3 0.2 0.082 13.4 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 TipAS PF07739.13 KPI41589.1 - 0.15 12.6 0.0 3.2 8.3 0.0 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Abhydro_lipase PF04083.16 KPI41589.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region CUE PF02845.16 KPI41590.1 - 1e-11 44.3 0.0 1.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain MFS_1 PF07690.16 KPI41593.1 - 2.3e-28 99.1 56.4 6.1e-17 61.6 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 KPI41594.1 - 0.043 13.5 1.0 0.078 12.6 1.0 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ASD2 PF08687.11 KPI41594.1 - 0.39 10.2 4.5 0.64 9.5 4.5 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Forkhead PF00250.18 KPI41595.1 - 7e-32 109.5 0.1 1.3e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain zf-C2H2 PF00096.26 KPI41596.1 - 2.2e-09 37.2 12.8 2.8e-05 24.3 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI41596.1 - 1.3e-06 28.8 10.1 0.0072 17.1 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPI41596.1 - 2e-06 28.0 10.7 6.5e-06 26.3 0.9 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KPI41596.1 - 0.0075 16.2 6.8 0.24 11.4 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI41596.1 - 0.014 15.6 2.6 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KPI41596.1 - 0.13 12.6 0.5 7.6 6.9 0.0 2.3 1 1 1 2 2 2 0 BolA-like protein zf-C2HE PF16278.5 KPI41596.1 - 0.69 10.4 6.7 6.6 7.3 0.6 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PAC3 PF10178.9 KPI41597.1 - 3.4e-06 27.1 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 zf-C3HC4_3 PF13920.6 KPI41598.1 - 0.24 11.3 5.7 1.4 8.8 2.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PI3K_1B_p101 PF10486.9 KPI41598.1 - 0.27 8.9 2.1 0.44 8.3 2.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MRP-S26 PF14943.6 KPI41598.1 - 1 9.2 15.6 2.5 8.0 4.5 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Peptidase_S49_N PF08496.10 KPI41598.1 - 4 7.5 14.6 0.49 10.5 5.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal U1snRNP70_N PF12220.8 KPI41598.1 - 6.4 7.5 14.6 3.9 8.2 4.8 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FANCL_C PF11793.8 KPI41598.1 - 6.5 7.0 7.1 48 4.2 0.0 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain STE PF02200.16 KPI41599.1 - 1.5e-55 186.3 0.0 2.4e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KPI41599.1 - 1.2e-10 41.3 12.0 2.3e-06 27.7 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI41599.1 - 1e-07 32.0 3.7 1e-07 32.0 3.7 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI41599.1 - 2.3e-06 28.0 13.0 0.0015 19.2 0.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KPI41599.1 - 0.00077 19.4 0.7 0.00077 19.4 0.7 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 KPI41599.1 - 0.0064 16.5 1.0 0.037 14.1 1.1 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_jaz PF12171.8 KPI41599.1 - 0.021 15.1 0.9 0.26 11.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribonuc_L-PSP PF01042.21 KPI41600.1 - 2.4e-08 34.0 0.0 4.5e-05 23.5 0.0 2.5 3 0 0 3 3 3 2 Endoribonuclease L-PSP UL141 PF16758.5 KPI41600.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 Herpes-like virus membrane glycoprotein UL141 Pyrid_oxidase_2 PF13883.6 KPI41601.1 - 3.8e-27 95.3 0.0 5.8e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 KPI41604.1 - 2.8e-75 252.4 0.1 4.3e-75 251.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KPI41604.1 - 1.6e-38 131.1 0.0 8.9e-38 128.7 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KPI41604.1 - 2.5e-38 131.0 0.0 1.1e-37 128.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KPI41604.1 - 7.5e-12 44.9 3.4 8.4e-12 44.8 1.0 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KPI41604.1 - 8.2e-11 41.8 0.0 1.7e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KPI41604.1 - 5e-10 39.2 0.0 8.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KPI41604.1 - 3.3e-05 24.0 0.0 6.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KPI41604.1 - 0.00036 20.4 0.2 0.00068 19.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 KPI41604.1 - 0.0018 18.0 0.6 0.019 14.8 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 KPI41604.1 - 0.0077 15.5 0.0 0.036 13.3 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp FMN_dh PF01070.18 KPI41605.1 - 4.5e-100 335.1 0.0 5.7e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPI41605.1 - 2.9e-15 56.2 0.0 5.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KPI41605.1 - 4.4e-06 26.1 0.0 7.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPI41605.1 - 0.0034 16.5 0.1 0.0058 15.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Rrn6 PF10214.9 KPI41606.1 - 0.089 11.3 12.2 0.13 10.7 12.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4203 PF13886.6 KPI41607.1 - 6.1e-53 179.5 24.3 8.5e-53 179.0 24.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CRT10 PF08728.10 KPI41607.1 - 8.7e-12 44.0 0.0 1e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 CRT10 PhoLip_ATPase_N PF16209.5 KPI41608.1 - 3.6e-16 58.6 2.0 6.7e-16 57.7 2.0 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KPI41608.1 - 1.2e-08 34.7 0.0 6.7e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPI41608.1 - 0.00075 19.5 0.0 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) adh_short PF00106.25 KPI41609.1 - 4.3e-17 62.2 0.6 2e-15 56.8 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41609.1 - 8.6e-10 38.6 0.2 9.9e-08 31.8 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pro_isomerase PF00160.21 KPI41611.1 - 1.6e-53 181.2 0.0 1.9e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2235 PF09994.9 KPI41615.1 - 2.7e-77 260.0 0.0 3.5e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ribos_L4_asso_C PF14374.6 KPI41615.1 - 0.31 11.1 1.6 4.8 7.3 0.2 2.8 3 0 0 3 3 3 0 60S ribosomal protein L4 C-terminal domain HEAT PF02985.22 KPI41616.1 - 1.9e-11 43.2 12.1 0.023 14.9 0.1 9.4 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 KPI41616.1 - 1.1e-08 35.4 10.2 7.9e-05 23.0 0.6 6.7 5 2 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 KPI41616.1 - 3.6e-06 27.1 0.0 0.027 14.5 0.0 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KPI41616.1 - 7.2e-05 23.2 11.5 1 10.0 0.0 7.7 8 0 0 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KPI41616.1 - 0.00045 20.8 0.0 0.1 13.2 0.0 3.7 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region DUF3510 PF12022.8 KPI41616.1 - 0.029 14.8 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) TAF6_C PF07571.13 KPI41616.1 - 0.39 11.1 5.5 61 4.0 0.0 6.1 6 1 1 7 7 7 0 TAF6 C-terminal HEAT repeat domain IFRD PF05004.13 KPI41616.1 - 0.88 8.6 9.0 0.27 10.3 0.0 4.2 5 2 0 6 6 6 0 Interferon-related developmental regulator (IFRD) Pkinase PF00069.25 KPI41618.1 - 5.9e-49 166.8 0.0 1e-48 166.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41618.1 - 2.6e-27 95.7 0.0 3.7e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPI41618.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPI41618.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KPI41618.1 - 0.04 13.9 1.1 1.5 8.6 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family PCO_ADO PF07847.12 KPI41619.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 PCO_ADO F-box PF00646.33 KPI41620.1 - 0.0073 16.2 0.1 0.064 13.2 0.0 2.4 2 0 0 2 2 2 1 F-box domain DUF2838 PF10998.8 KPI41621.1 - 2.7e-41 140.3 12.0 2.7e-41 140.3 12.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) bZIP_Maf PF03131.17 KPI41621.1 - 5.6 7.5 9.6 0.64 10.6 5.3 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Bmt2 PF11968.8 KPI41622.1 - 2.1e-50 171.6 0.0 5.1e-50 170.4 0.0 1.6 1 1 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 GTP_EFTU_D2 PF03144.25 KPI41622.1 - 0.18 12.2 0.0 0.59 10.6 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 ALS_ss_C PF10369.9 KPI41623.1 - 3.7e-15 55.9 0.0 1.2e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KPI41623.1 - 1e-12 47.6 0.2 4e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 KPI41623.1 - 3.5e-08 33.1 0.0 8.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 ACT domain GreA_GreB_N PF03449.15 KPI41623.1 - 0.04 14.1 2.6 0.11 12.7 2.6 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal ACT_6 PF13740.6 KPI41623.1 - 0.063 13.3 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 ACT domain DbpA PF03880.15 KPI41624.1 - 0.13 12.2 0.2 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 DbpA RNA binding domain CBFD_NFYB_HMF PF00808.23 KPI41627.1 - 7.7e-19 67.8 0.6 1.3e-18 67.0 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPI41627.1 - 9.9e-16 58.3 0.2 9.9e-16 58.3 0.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KPI41627.1 - 0.056 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pex14_N PF04695.13 KPI41627.1 - 1.3 9.7 10.6 2.6 8.7 10.6 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Troponin PF00992.20 KPI41628.1 - 3.7 7.8 11.2 8.7 6.6 11.2 1.5 1 0 0 1 1 1 0 Troponin Glyco_trans_2_3 PF13632.6 KPI41629.1 - 9.7e-17 61.5 0.3 9.7e-17 61.5 0.3 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPI41629.1 - 2.4e-14 53.8 0.0 3.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI41629.1 - 6.9e-12 45.5 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KPI41629.1 - 2.2e-11 43.0 6.6 9.3e-10 37.6 5.0 2.2 1 1 1 2 2 2 2 Cellulose synthase Glyco_transf_21 PF13506.6 KPI41629.1 - 2e-09 37.1 0.0 3.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KPI41629.1 - 0.0019 16.9 0.2 0.072 11.7 0.4 2.5 3 0 0 3 3 3 1 Chitin synthase SANT_DAMP1_like PF16282.5 KPI41629.1 - 0.12 12.6 0.1 0.44 10.8 0.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 BAR PF03114.18 KPI41630.1 - 3.2e-60 203.8 1.8 3.8e-60 203.5 1.8 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KPI41630.1 - 0.013 16.2 0.0 0.082 13.7 0.0 2.4 2 1 0 2 2 2 0 CP12 domain DUF3340 PF11818.8 KPI41630.1 - 0.026 14.7 0.6 0.026 14.7 0.6 1.7 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Arfaptin PF06456.13 KPI41630.1 - 0.072 12.7 2.8 0.26 10.8 2.8 1.9 1 1 0 1 1 1 0 Arfaptin-like domain DUF3450 PF11932.8 KPI41630.1 - 0.16 11.3 4.5 0.17 11.1 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF5339 PF17274.2 KPI41630.1 - 0.26 12.1 1.9 0.88 10.5 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5339) FliD_N PF02465.18 KPI41630.1 - 0.59 10.9 2.5 7.6 7.3 0.2 2.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SVIP PF15811.5 KPI41630.1 - 3 8.3 7.6 0.19 12.2 1.3 2.3 2 1 0 2 2 2 0 Small VCP/p97-interacting protein IATP PF04568.12 KPI41631.1 - 0.016 15.6 1.3 0.016 15.6 1.3 1.8 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF1476 PF07345.11 KPI41631.1 - 0.073 13.4 0.2 0.092 13.1 0.2 1.1 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Lactamase_B PF00753.27 KPI41632.1 - 8e-07 29.3 1.6 1.8e-06 28.1 1.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI41632.1 - 6.5e-05 22.5 0.5 9.1e-05 22.1 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_M74 PF03411.13 KPI41632.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase SOG2 PF10428.9 KPI41633.1 - 2.4e-90 304.2 4.0 2.4e-90 304.2 4.0 3.2 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 KPI41633.1 - 1.2e-18 66.6 16.5 1.1e-10 41.1 1.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KPI41633.1 - 3.8e-08 33.5 4.0 1.3e-05 25.4 1.2 2.9 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPI41633.1 - 0.037 14.1 9.1 4.3 7.7 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KPI41633.1 - 0.14 12.8 6.2 5.1 8.0 0.1 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat HET PF06985.11 KPI41634.1 - 1.6e-07 31.8 0.0 2.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1416 PF07210.12 KPI41636.1 - 0.09 12.7 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) PPR PF01535.20 KPI41636.1 - 0.14 12.5 0.1 0.43 10.9 0.1 1.9 1 0 0 1 1 1 0 PPR repeat tRNA-synt_2b PF00587.25 KPI41638.1 - 4e-33 114.9 0.1 1.4e-32 113.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KPI41638.1 - 9e-13 48.4 5.2 2e-12 47.3 5.2 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain eIF3_N PF09440.10 KPI41638.1 - 0.35 11.3 4.3 0.16 12.4 1.8 1.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain SF-assemblin PF06705.11 KPI41638.1 - 1.9 7.8 11.4 3.5 6.9 6.6 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin SE PF08491.10 KPI41639.1 - 5.6e-101 337.2 0.0 7.7e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KPI41639.1 - 4.7e-12 45.8 0.1 3.8e-11 42.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPI41639.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KPI41639.1 - 2.4e-05 24.1 0.1 0.12 12.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KPI41639.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI41639.1 - 0.034 13.2 0.7 0.76 8.8 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPI41639.1 - 0.035 13.4 0.6 2.2 7.5 0.3 2.4 2 1 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KPI41639.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KPI41639.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 KPI41639.1 - 0.14 11.0 1.2 6.5 5.5 0.0 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KPI41639.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI41639.1 - 0.17 12.1 0.7 0.53 10.6 0.5 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cohesin_load PF10345.9 KPI41640.1 - 6.3e-77 259.4 13.3 8.5e-77 259.0 13.3 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_1 PF00515.28 KPI41640.1 - 2.7e-05 23.8 4.8 0.022 14.6 0.4 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI41640.1 - 0.00048 20.0 8.4 0.043 13.9 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI41640.1 - 0.0034 17.5 6.9 0.74 10.2 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPI41640.1 - 0.38 11.1 23.2 0.098 13.0 1.0 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI41640.1 - 0.44 11.5 8.1 5.9 8.0 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Med6 PF04934.14 KPI41641.1 - 3.1e-28 98.2 0.0 4.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Ufd2P_core PF10408.9 KPI41641.1 - 0.23 10.0 0.1 0.31 9.6 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core Mid1 PF12929.7 KPI41642.1 - 4.1e-150 500.7 0.4 4.7e-150 500.5 0.4 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KPI41642.1 - 0.0015 19.1 7.7 0.14 12.8 3.3 2.7 2 1 0 2 2 2 2 Fz domain Glyoxalase_2 PF12681.7 KPI41643.1 - 0.001 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KPI41643.1 - 0.0012 19.1 0.1 0.0013 18.9 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GST_N_3 PF13417.6 KPI41644.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI41644.1 - 9.5e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI41644.1 - 2.4e-05 24.5 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI41644.1 - 0.00017 21.8 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI41644.1 - 0.00086 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI41644.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain adh_short_C2 PF13561.6 KPI41645.1 - 1.2e-52 178.8 0.1 2.6e-47 161.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI41645.1 - 9.5e-36 123.1 0.4 1.6e-27 96.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI41645.1 - 1.4e-12 47.9 0.1 4.8e-12 46.2 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI41645.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KPI41645.1 - 0.021 14.8 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Rhomboid_N PF12122.8 KPI41645.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Lyase_1 PF00206.20 KPI41647.1 - 1.2e-110 369.8 0.0 1.7e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KPI41647.1 - 3.2e-20 72.3 0.1 8.8e-20 70.9 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Rtt106_N PF18215.1 KPI41647.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain Form_Nir_trans PF01226.17 KPI41648.1 - 3e-25 89.0 22.8 9.7e-12 44.7 8.3 3.1 2 1 0 2 2 2 2 Formate/nitrite transporter FUSC_2 PF13515.6 KPI41649.1 - 9.2e-30 103.4 4.2 9.2e-30 103.4 4.2 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KPI41649.1 - 2.5e-06 26.3 0.5 2.5e-06 26.3 0.5 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 KPI41649.1 - 5.2e-06 26.5 0.3 4.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KPI41649.1 - 0.00015 20.7 15.8 0.00053 19.0 11.4 3.1 3 1 0 3 3 3 1 Aluminium activated malate transporter PHO4 PF01384.20 KPI41649.1 - 0.0022 17.1 0.1 0.0022 17.1 0.1 2.2 2 1 0 2 2 2 1 Phosphate transporter family DUF2456 PF10445.9 KPI41649.1 - 8.1 6.6 8.9 9.4 6.4 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2456) HA2 PF04408.23 KPI41650.1 - 2.8e-14 53.3 0.2 7.4e-14 51.9 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KPI41650.1 - 1.8e-12 47.4 0.0 4.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KPI41650.1 - 8e-11 42.3 0.0 2.6e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI41650.1 - 8.9e-07 28.8 0.2 1.6e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KPI41650.1 - 3.3e-06 27.4 0.0 8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI41650.1 - 3.5e-05 23.6 0.1 6.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KPI41650.1 - 4.3e-05 23.9 0.1 9.9e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KPI41650.1 - 0.0037 17.8 1.0 0.052 14.1 0.2 2.8 2 1 0 2 2 2 1 ABC transporter TrwB_AAD_bind PF10412.9 KPI41650.1 - 0.0089 15.0 0.1 0.02 13.8 0.1 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 KPI41650.1 - 0.017 15.7 0.2 0.061 13.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KPI41650.1 - 0.05 12.9 0.0 1.5 8.1 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family T2SSE PF00437.20 KPI41650.1 - 0.061 12.4 0.1 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 KPI41650.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KPI41650.1 - 0.088 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 KPI41650.1 - 0.12 12.0 0.5 0.66 9.5 0.0 2.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 KPI41650.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC MIP PF00230.20 KPI41651.1 - 1.6e-32 113.1 11.3 1.8e-32 112.9 11.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_U4 PF03419.13 KPI41651.1 - 7.1 5.8 6.9 8.1 5.6 6.9 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Promethin PF16015.5 KPI41652.1 - 2.5 8.1 10.8 0.086 12.8 2.0 2.1 2 0 0 2 2 2 0 Promethin LRR_6 PF13516.6 KPI41653.1 - 0.00027 20.7 3.7 53 4.2 0.0 6.3 5 0 0 5 5 5 2 Leucine Rich repeat DnaB_bind PF10410.9 KPI41653.1 - 0.12 12.5 0.1 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Mob_Pre PF01076.19 KPI41654.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Plasmid recombination enzyme CCDC71L PF15374.6 KPI41654.1 - 0.055 12.7 7.5 0.12 11.7 7.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 71L DKCLD PF08068.12 KPI41655.1 - 5.2e-32 109.7 0.1 3.1e-30 104.0 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KPI41655.1 - 4.7e-23 81.1 0.3 9.4e-23 80.1 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KPI41655.1 - 1.1e-22 81.0 0.2 7.5e-20 71.8 0.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KPI41655.1 - 2.7e-21 75.3 0.9 4.7e-21 74.5 0.9 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KPI41655.1 - 0.00046 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Ribosomal_L24e PF01246.20 KPI41656.1 - 4.7e-28 97.2 0.3 4.7e-28 97.2 0.3 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e U3_snoRNA_assoc PF08297.11 KPI41656.1 - 3.3 8.5 15.1 0.21 12.3 9.2 1.9 1 1 1 2 2 2 0 U3 snoRNA associated Vps54_N PF10475.9 KPI41657.1 - 0.00018 20.9 6.1 0.00027 20.3 6.1 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 KPI41657.1 - 0.00096 19.2 6.2 0.0011 19.0 4.1 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KPI41657.1 - 0.0017 18.6 1.8 0.0017 18.6 1.8 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KPI41657.1 - 0.0078 16.1 5.6 0.0078 16.1 5.6 2.5 1 1 0 2 2 2 1 Sec8 exocyst complex component specific domain ApoLp-III PF07464.11 KPI41657.1 - 0.011 15.8 4.9 0.011 15.8 4.9 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2587 PF10759.9 KPI41657.1 - 0.037 13.5 0.7 0.11 12.0 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2587) AAA_5 PF07728.14 KPI41657.1 - 0.059 13.4 0.6 0.13 12.2 0.6 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sec5 PF15469.6 KPI41657.1 - 0.085 12.7 8.7 0.2 11.4 8.5 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 YfdX PF10938.8 KPI41657.1 - 0.74 9.7 4.7 4.1 7.3 0.5 3.0 2 1 1 3 3 3 0 YfdX protein F-box-like_2 PF13013.6 KPI41658.1 - 0.0073 16.3 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 F-box-like domain GHMP_kinases_N PF00288.26 KPI41659.1 - 0.00034 20.8 0.1 0.00076 19.7 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPI41659.1 - 0.00041 20.7 0.0 0.00095 19.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal adh_short PF00106.25 KPI41660.1 - 1.8e-11 43.9 1.1 2.5e-11 43.4 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41660.1 - 2.1e-08 34.1 0.1 2.8e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Meth_synt_2 PF01717.18 KPI41661.1 - 8.5e-129 429.5 0.2 4.4e-106 354.8 0.0 3.6 2 1 1 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KPI41661.1 - 3e-122 408.0 0.1 7.4e-116 387.0 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KPI41661.1 - 0.00018 20.8 0.1 0.16 11.1 0.0 2.8 2 1 1 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.10 KPI41661.1 - 7.2 6.8 10.0 2.1 8.6 3.0 3.1 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) Sec15 PF04091.12 KPI41662.1 - 4.7e-96 321.9 5.0 5.7e-96 321.6 5.0 1.1 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 KPI41662.1 - 2.6e-05 24.1 0.2 4.8e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF3510 PF12022.8 KPI41662.1 - 0.02 15.3 0.1 3.3 8.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Pkinase PF00069.25 KPI41663.1 - 1.5e-66 224.4 0.0 1.7e-65 221.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41663.1 - 4.7e-37 127.7 0.0 5e-35 121.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI41663.1 - 1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPI41663.1 - 0.00053 19.4 0.0 0.002 17.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI41663.1 - 0.0033 17.4 0.0 0.012 15.6 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI41663.1 - 0.0062 15.9 0.0 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KPI41663.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NIF PF03031.18 KPI41664.1 - 4.9e-59 198.6 0.0 7.1e-59 198.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SPT_ssu-like PF11779.8 KPI41666.1 - 1.5e-21 75.7 4.7 2e-21 75.3 4.7 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF1624 PF07786.12 KPI41666.1 - 0.0065 16.0 0.8 0.0078 15.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) Ferlin_C PF16165.5 KPI41666.1 - 0.028 14.4 0.7 0.04 13.9 0.7 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Stealth_CR2 PF11380.8 KPI41667.1 - 5.3e-18 65.2 0.6 8.3e-17 61.3 0.6 2.5 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 KPI41667.1 - 3.8e-05 23.5 0.0 9.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 KPI41667.1 - 0.0008 19.1 0.0 0.003 17.3 0.0 2.0 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KPI41667.1 - 0.02 14.8 0.3 0.043 13.7 0.3 1.6 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 ABM PF03992.16 KPI41668.1 - 0.011 15.8 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF4605 PF15378.6 KPI41669.1 - 0.0021 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Isochorismatase PF00857.20 KPI41670.1 - 3e-37 128.5 0.0 3.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF87 PF01935.17 KPI41670.1 - 0.014 15.5 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Pantoate_transf PF02548.15 KPI41670.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Lys-AminoMut_A PF09043.11 KPI41670.1 - 0.068 11.6 0.0 0.092 11.2 0.0 1.3 1 1 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit HALZ PF02183.18 KPI41671.1 - 2.9e-05 24.2 9.6 0.0073 16.5 1.6 4.2 4 1 1 5 5 5 2 Homeobox associated leucine zipper DUF3450 PF11932.8 KPI41671.1 - 0.017 14.5 2.1 0.037 13.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4472 PF14739.6 KPI41671.1 - 0.092 13.5 4.8 4.6 8.0 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) DUF4407 PF14362.6 KPI41671.1 - 0.15 11.4 2.7 0.25 10.7 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KPI41671.1 - 0.21 10.9 6.3 7.1 5.9 5.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 KPI41671.1 - 0.41 10.9 2.0 2.4 8.4 1.6 2.4 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II TelA PF05816.11 KPI41671.1 - 0.57 9.2 6.8 3.2 6.7 3.3 2.1 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) SWIRM-assoc_1 PF16495.5 KPI41671.1 - 0.7 9.9 5.2 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 SWIRM-associated region 1 BRE1 PF08647.11 KPI41671.1 - 1.8 8.7 6.0 2 8.5 2.3 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase PAP_assoc PF03828.19 KPI41672.1 - 5.2e-16 58.6 0.1 1.4e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KPI41672.1 - 5.3e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KPI41672.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Fungal_trans PF04082.18 KPI41673.1 - 0.00067 18.8 0.3 0.0017 17.4 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF917 PF06032.12 KPI41674.1 - 3e-111 371.6 0.4 4.8e-111 371.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KPI41674.1 - 1.5e-19 70.4 0.5 3.6e-16 59.3 0.1 2.4 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase StbA PF06406.11 KPI41674.1 - 0.0049 16.1 0.5 2.5 7.2 0.1 2.6 3 0 0 3 3 3 2 StbA protein DUF4073 PF13285.6 KPI41674.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) TRAM_LAG1_CLN8 PF03798.16 KPI41675.1 - 5.5e-40 137.2 15.1 5.5e-40 137.2 15.1 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KPI41675.1 - 3.5e-20 71.4 0.9 3.5e-20 71.4 0.9 2.0 2 0 0 2 2 2 1 TRAM1-like protein NmrA PF05368.13 KPI41676.1 - 1.4e-24 87.0 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI41676.1 - 6.6e-13 48.9 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPI41676.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KPI41676.1 - 0.00029 20.9 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KPI41676.1 - 0.00056 20.1 0.2 0.0021 18.3 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.21 KPI41676.1 - 0.009 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI41676.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 KR domain CbiJ PF02571.14 KPI41676.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Sec16_C PF12931.7 KPI41677.1 - 4.8e-103 345.0 0.0 6.9e-103 344.4 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KPI41677.1 - 1.4e-30 106.3 0.0 3.4e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region MraY_sig1 PF10555.9 KPI41677.1 - 0.1 12.2 1.9 0.32 10.6 1.9 1.9 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 ERCC4 PF02732.15 KPI41678.1 - 4e-16 59.6 0.0 8.2e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain p450 PF00067.22 KPI41679.1 - 6.7e-72 242.7 0.0 1.3e-71 241.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.23 KPI41680.1 - 0.0038 17.3 11.3 0.0075 16.3 10.6 1.7 1 1 0 1 1 1 1 Membrane-associating domain G10 PF01125.17 KPI41681.1 - 1.6e-57 193.3 9.6 3.4e-57 192.3 9.6 1.5 1 1 0 1 1 1 1 G10 protein P5-ATPase PF12409.8 KPI41682.1 - 1.1e-38 132.2 0.0 2.6e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KPI41682.1 - 5.3e-26 91.2 0.0 1.6e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KPI41682.1 - 3.1e-13 50.5 0.0 0.00041 20.7 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPI41682.1 - 0.0035 17.4 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPI41682.1 - 0.0068 16.1 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI41682.1 - 0.14 11.9 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SMC_N PF02463.19 KPI41684.1 - 1.4e-41 142.3 0.0 8.4e-41 139.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPI41684.1 - 2.7e-14 53.5 0.0 2.4e-13 50.4 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 KPI41684.1 - 0.00077 19.6 0.1 0.0041 17.3 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KPI41684.1 - 0.00083 19.2 0.0 0.00083 19.2 0.0 3.1 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Lebercilin PF15619.6 KPI41684.1 - 0.0048 16.6 15.2 0.0048 16.6 15.2 6.2 5 1 1 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease NADH_u_ox_C PF12853.7 KPI41684.1 - 0.54 10.3 3.4 1.7 8.7 0.1 3.4 3 0 0 3 3 3 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Baculo_PEP_C PF04513.12 KPI41684.1 - 4.2 7.4 28.3 1.3 9.0 0.2 6.5 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 KPI41684.1 - 7.2 6.3 80.6 2.3 7.9 3.4 7.5 4 2 3 7 7 7 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 KPI41684.1 - 8.1 6.6 102.5 0.68 10.1 1.8 7.9 4 2 2 7 7 7 0 Autophagy protein 16 (ATG16) fn3_2 PF16893.5 KPI41685.1 - 1.7e-34 117.8 0.2 2.6e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KPI41685.1 - 1.7e-23 82.3 0.8 2.7e-23 81.7 0.8 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KPI41685.1 - 4.8e-15 55.2 0.0 3.5e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KPI41685.1 - 1.1e-10 41.7 0.0 2.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KPI41685.1 - 1.8e-05 25.1 0.0 4.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KPI41685.1 - 0.00014 22.0 0.0 0.00039 20.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KPI41685.1 - 0.016 15.5 0.1 0.081 13.3 0.1 2.1 1 1 0 1 1 1 0 Fibronectin type III domain Epimerase PF01370.21 KPI41687.1 - 0.0088 15.5 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI41687.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KPI41687.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Ham1p_like PF01725.16 KPI41688.1 - 7.1e-49 166.3 0.0 1e-44 152.7 0.0 2.0 2 0 0 2 2 2 2 Ham1 family GFA PF04828.14 KPI41689.1 - 1.4e-15 57.4 0.8 2.6e-14 53.3 0.8 2.1 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KPI41689.1 - 0.0085 16.2 1.1 0.21 11.8 0.0 2.3 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like DUF2321 PF10083.9 KPI41689.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) MIP PF00230.20 KPI41690.1 - 1.1e-26 94.0 8.8 1.4e-26 93.6 8.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein CbtB PF09489.10 KPI41690.1 - 0.05 13.7 0.2 0.05 13.7 0.2 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) NAP PF00956.18 KPI41691.1 - 2.4e-98 328.6 9.3 2.4e-98 328.6 9.3 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 KPI41691.1 - 4.9 7.4 30.0 0.86 9.8 20.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pkinase PF00069.25 KPI41692.1 - 6.2e-66 222.5 0.0 8.4e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41692.1 - 6.3e-31 107.6 0.0 1.1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI41692.1 - 0.00066 19.1 0.0 0.0039 16.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like DUF2744 PF10910.8 KPI41692.1 - 0.02 14.9 0.2 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) Kdo PF06293.14 KPI41692.1 - 0.067 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPI41692.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase AAA_18 PF13238.6 KPI41693.1 - 9.5e-18 65.0 0.1 1.8e-09 38.2 0.0 2.5 2 1 1 3 3 3 2 AAA domain NTPase_1 PF03266.15 KPI41693.1 - 0.00043 20.2 0.5 0.00092 19.2 0.2 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 KPI41693.1 - 0.00048 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI41693.1 - 0.00086 19.7 0.0 0.00086 19.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KPI41693.1 - 0.0013 19.0 0.1 0.0029 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KPI41693.1 - 0.0017 18.7 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KPI41693.1 - 0.0044 17.4 0.0 0.0071 16.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KPI41693.1 - 0.0054 17.1 0.1 0.77 10.2 0.0 2.7 1 1 2 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 KPI41693.1 - 0.0082 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 KPI41693.1 - 0.009 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KPI41693.1 - 0.013 15.6 0.2 0.021 14.9 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KPI41693.1 - 0.013 15.2 0.4 0.032 14.0 0.2 1.7 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KPI41693.1 - 0.016 15.0 0.0 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KPI41693.1 - 0.016 14.5 0.2 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.6 KPI41693.1 - 0.021 14.6 0.6 0.044 13.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KPI41693.1 - 0.023 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KPI41693.1 - 0.035 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 KPI41693.1 - 0.039 13.0 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 KPI41693.1 - 0.042 12.8 1.0 0.2 10.6 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KPI41693.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KPI41693.1 - 0.068 13.1 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KPI41693.1 - 0.07 13.3 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KPI41693.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 KPI41693.1 - 0.14 12.6 0.2 0.21 12.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KPI41693.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 KPI41693.1 - 0.79 9.2 2.5 2.3 7.7 0.1 2.3 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain CASP_C PF08172.12 KPI41694.1 - 0.13 11.5 0.2 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 CASP C terminal DUF3684 PF12449.8 KPI41695.1 - 0 1352.3 0.0 0 1352.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KPI41695.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KPI41695.1 - 1 9.4 3.6 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 WLM domain SAM_PNT PF02198.16 KPI41695.1 - 1.3 9.0 6.3 8.1 6.5 0.2 3.2 4 0 0 4 4 4 0 Sterile alpha motif (SAM)/Pointed domain AP3D1 PF06375.11 KPI41696.1 - 0.006 16.8 6.5 0.0081 16.4 6.5 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Med19 PF10278.9 KPI41696.1 - 0.014 15.4 10.2 0.019 14.9 10.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CPSF100_C PF13299.6 KPI41696.1 - 0.026 14.7 2.4 0.032 14.4 2.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 KPI41696.1 - 0.03 14.1 3.3 0.053 13.3 3.3 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 KPI41696.1 - 0.037 12.8 5.0 0.046 12.5 5.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TPPII_N PF12583.8 KPI41696.1 - 0.046 14.3 9.9 0.07 13.7 9.9 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Dicty_REP PF05086.12 KPI41696.1 - 0.046 11.7 12.4 0.055 11.5 12.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2448 PF10476.9 KPI41696.1 - 0.1 12.4 0.5 0.16 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Connexin PF00029.19 KPI41696.1 - 0.36 10.5 1.7 0.47 10.2 1.7 1.1 1 0 0 1 1 1 0 Connexin FAM199X PF15814.5 KPI41696.1 - 0.48 9.4 4.8 0.72 8.8 4.8 1.3 1 0 0 1 1 1 0 Protein family FAM199X SMYLE_N PF18615.1 KPI41696.1 - 0.5 9.9 3.6 0.55 9.7 3.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CCDC106 PF15794.5 KPI41696.1 - 0.59 9.8 12.1 0.58 9.8 11.3 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sec62 PF03839.16 KPI41696.1 - 0.61 9.6 5.5 0.86 9.1 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.10 KPI41696.1 - 0.78 9.8 4.9 1.2 9.2 4.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 KPI41696.1 - 1.1 8.0 3.0 1.3 7.7 3.0 1.1 1 0 0 1 1 1 0 Presenilin UPF0239 PF06783.11 KPI41696.1 - 2.6 8.3 9.0 4.4 7.6 9.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) TSGP1 PF07771.11 KPI41696.1 - 3.1 8.0 12.4 5 7.3 12.4 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 FH2 PF02181.23 KPI41697.1 - 3.5e-83 279.8 3.7 3.5e-83 279.8 3.7 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KPI41697.1 - 1.6e-64 217.0 0.0 1.6e-64 217.0 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KPI41697.1 - 1.9e-52 177.7 3.4 3e-51 173.8 0.7 3.6 2 1 1 3 3 3 1 Diaphanous FH3 Domain ISG65-75 PF11727.8 KPI41697.1 - 6.4 5.9 7.7 14 4.8 2.6 2.7 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF1479 PF07350.12 KPI41698.1 - 2.1e-163 543.9 0.0 2.5e-163 543.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF5597 PF18120.1 KPI41699.1 - 2.7e-24 85.8 0.0 5.8e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KPI41699.1 - 1.4e-10 41.1 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 KPI41699.1 - 4.7e-10 39.6 0.0 8.9e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Suf PF05843.14 KPI41700.1 - 2e-65 221.7 0.0 2e-65 221.7 0.0 3.1 5 1 1 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KPI41700.1 - 8.3e-07 29.3 0.6 0.21 12.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPI41700.1 - 0.00057 20.3 0.0 0.12 12.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ESM4 PF15952.5 KPI41700.1 - 0.099 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Enhancer of split M4 family WAPL PF07814.13 KPI41701.1 - 1.8e-27 96.1 9.0 3.4e-27 95.2 9.0 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin BP28CT PF08146.12 KPI41701.1 - 0.024 14.5 0.4 0.89 9.4 0.1 2.5 2 0 0 2 2 2 0 BP28CT (NUC211) domain TFIID-18kDa PF02269.16 KPI41702.1 - 1.1e-14 54.2 0.0 8e-13 48.2 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 KPI41702.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KPI41702.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 KPI41702.1 - 0.064 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 KPI41702.1 - 0.073 13.4 0.1 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KPI41702.1 - 0.19 12.1 0.1 0.4 11.1 0.0 1.5 1 1 0 1 1 1 0 CENP-S protein FAD_binding_3 PF01494.19 KPI41703.1 - 2.3e-17 63.3 0.0 3.5e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Abhydrolase_3 PF07859.13 KPI41703.1 - 0.00094 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KPI41703.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold EXS PF03124.14 KPI41704.1 - 2.6e-111 372.1 12.9 2.9e-111 372.0 12.9 1.0 1 0 0 1 1 1 1 EXS family Sec8_exocyst PF04048.14 KPI41705.1 - 2e-29 102.3 0.3 9.8e-28 96.8 0.1 3.1 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KPI41705.1 - 0.0051 16.1 0.2 0.013 14.8 0.2 1.6 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF1572 PF07609.11 KPI41705.1 - 0.065 13.0 0.3 1.5 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Vps51 PF08700.11 KPI41705.1 - 0.093 12.8 0.0 0.48 10.5 0.0 2.2 1 0 0 1 1 1 0 Vps51/Vps67 KH_1 PF00013.29 KPI41706.1 - 1.8e-09 37.3 0.1 1.4e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 KH domain PEHE PF15275.6 KPI41706.1 - 0.055 14.1 2.1 0.23 12.1 2.1 2.1 1 0 0 1 1 1 0 PEHE domain ATLF PF07737.11 KPI41706.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain F-box PF00646.33 KPI41707.1 - 0.00085 19.1 0.4 0.00085 19.1 0.4 1.9 2 0 0 2 2 2 1 F-box domain Parecho_VpG PF06344.11 KPI41707.1 - 0.21 12.3 0.3 0.61 10.8 0.3 1.7 1 0 0 1 1 1 0 Parechovirus Genome-linked protein Glyco_hydro_76 PF03663.14 KPI41708.1 - 2.4e-154 514.3 14.2 2.8e-154 514.1 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPI41708.1 - 0.0011 18.1 4.0 0.039 13.0 0.7 2.6 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Sec61_beta PF03911.16 KPI41708.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Sec61beta family Sec34 PF04136.15 KPI41709.1 - 1.5e-47 161.2 5.4 1.5e-47 161.2 5.4 2.2 2 0 0 2 2 2 1 Sec34-like family ALIX_LYPXL_bnd PF13949.6 KPI41709.1 - 0.0027 17.0 7.5 0.0082 15.5 2.6 2.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Exo70 PF03081.15 KPI41709.1 - 0.03 13.4 3.6 0.95 8.4 0.0 2.9 3 1 0 3 3 3 0 Exo70 exocyst complex subunit DUF4795 PF16043.5 KPI41709.1 - 0.34 10.5 3.7 0.25 10.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) FerA PF08165.11 KPI41709.1 - 0.52 10.3 2.5 0.49 10.4 0.2 2.2 2 0 0 2 2 2 0 FerA (NUC095) domain DUF3585 PF12130.8 KPI41709.1 - 0.57 10.3 3.9 0.29 11.3 0.9 2.1 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain Occludin_ELL PF07303.13 KPI41709.1 - 1.2 9.9 6.6 13 6.6 1.4 3.8 3 0 0 3 3 3 0 Occludin homology domain Jnk-SapK_ap_N PF09744.9 KPI41709.1 - 5.4 7.2 15.1 1.2 9.4 4.0 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 FliJ PF02050.16 KPI41709.1 - 5.5 7.2 10.4 9 6.5 0.0 3.4 2 1 0 3 3 3 0 Flagellar FliJ protein FAD_binding_7 PF03441.14 KPI41710.1 - 7.5e-44 149.6 0.0 1.5e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPI41710.1 - 4e-20 72.4 0.0 7.4e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase GARS_A PF01071.19 KPI41711.1 - 1.1e-83 279.9 0.0 1.8e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KPI41711.1 - 1.7e-38 132.2 0.1 5.1e-38 130.7 0.1 1.8 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KPI41711.1 - 8.7e-31 106.6 0.3 4.6e-30 104.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KPI41711.1 - 5.7e-27 93.8 2.1 7.3e-27 93.5 0.4 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KPI41711.1 - 3.8e-13 49.9 3.7 3.8e-13 49.9 3.7 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KPI41711.1 - 3e-05 23.6 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KPI41711.1 - 0.00035 20.6 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KPI41711.1 - 0.0052 16.4 0.1 0.047 13.3 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 KPI41711.1 - 0.0096 15.2 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 KPI41711.1 - 0.013 14.9 0.1 0.061 12.7 0.1 2.0 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain CPSase_L_D2 PF02786.17 KPI41711.1 - 0.019 14.5 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KPI41711.1 - 0.045 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 KPI41711.1 - 0.096 12.2 0.1 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain HRI1 PF16815.5 KPI41712.1 - 6.8e-37 127.4 0.0 8.3e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 EamA PF00892.20 KPI41714.1 - 5.4e-14 52.5 25.1 5.6e-09 36.3 5.6 3.3 3 0 0 3 3 3 3 EamA-like transporter family RabGAP-TBC PF00566.18 KPI41715.1 - 5.4e-31 107.9 17.7 5.1e-30 104.7 4.5 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KPI41715.1 - 7.1e-08 32.1 0.0 1.8e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Rab-binding domain (RBD) CortBP2 PF09727.9 KPI41715.1 - 0.075 12.9 1.4 0.22 11.4 1.4 1.8 1 0 0 1 1 1 0 Cortactin-binding protein-2 Carboxyl_trans PF01039.22 KPI41716.1 - 3.4e-139 464.7 0.3 4.1e-139 464.4 0.3 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 KPI41716.1 - 0.19 11.0 1.7 0.26 10.6 0.1 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF805 PF05656.14 KPI41717.1 - 0.24 11.8 2.1 1.3 9.4 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DEAD PF00270.29 KPI41719.1 - 2.9e-36 124.8 0.2 6e-36 123.8 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI41719.1 - 2.6e-27 95.4 0.1 1.3e-24 86.7 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KPI41719.1 - 4.8e-08 33.2 0.0 9.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPI41719.1 - 0.055 12.8 0.1 0.17 11.2 0.1 1.7 1 1 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Cyclin PF08613.11 KPI41720.1 - 3e-05 24.4 0.0 3e-05 24.4 0.0 2.8 4 0 0 4 4 4 1 Cyclin Cyclin_N PF00134.23 KPI41720.1 - 0.031 14.0 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF1640 PF07798.11 KPI41721.1 - 0.0073 16.4 2.1 0.025 14.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DegS PF05384.11 KPI41721.1 - 0.41 10.1 5.9 0.062 12.8 1.6 1.7 2 0 0 2 2 2 0 Sensor protein DegS FlaC_arch PF05377.11 KPI41721.1 - 0.68 10.4 4.6 0.22 12.0 0.5 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KPI41721.1 - 0.93 10.2 5.2 6.1 7.5 1.0 2.8 2 0 0 2 2 2 0 SlyX CENP-F_N PF10481.9 KPI41721.1 - 1.8 8.1 13.2 11 5.5 13.4 1.9 1 1 0 1 1 1 0 Cenp-F N-terminal domain DivIC PF04977.15 KPI41721.1 - 1.9 8.3 7.4 0.66 9.8 3.2 2.0 2 0 0 2 2 2 0 Septum formation initiator BMFP PF04380.13 KPI41721.1 - 2.8 8.5 8.0 0.26 11.8 3.2 1.8 2 0 0 2 2 2 0 Membrane fusogenic activity DivIVA PF05103.13 KPI41721.1 - 3.5 7.7 7.4 1.2 9.2 1.0 2.3 2 0 0 2 2 2 0 DivIVA protein HALZ PF02183.18 KPI41721.1 - 3.8 7.8 7.7 0.22 11.8 2.3 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4345 PF14248.6 KPI41722.1 - 6.8e-21 74.4 2.8 7.5e-21 74.2 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) UTP25 PF06862.12 KPI41723.1 - 1.3e-169 565.0 0.0 1.5e-169 564.8 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Phage_holin_7_1 PF16081.5 KPI41724.1 - 0.19 11.9 0.4 24 5.1 0.2 2.1 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family CALM_bind PF16025.5 KPI41725.1 - 1.2 9.6 7.5 2.6 8.6 7.5 1.5 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding IF-2B PF01008.17 KPI41727.1 - 4.2e-45 154.1 0.0 2.6e-21 76.1 0.1 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Fungal_trans_2 PF11951.8 KPI41728.1 - 1.6e-11 43.7 1.1 1.6e-11 43.7 1.1 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI41728.1 - 0.00095 19.2 9.0 0.0022 18.1 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KPI41729.1 - 5.2e-24 84.1 21.8 3.1e-09 37.3 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI41729.1 - 1.3e-07 31.8 0.5 0.049 13.9 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI41729.1 - 0.00012 21.2 0.8 0.0069 15.4 0.0 3.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_1 PF07690.16 KPI41730.1 - 9.8e-42 143.1 17.7 1.5e-41 142.6 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2985 PF11204.8 KPI41730.1 - 0.17 12.0 5.8 55 4.0 5.5 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2985) Skp1 PF01466.19 KPI41731.1 - 2.5e-28 97.9 0.5 5e-28 97.0 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KPI41731.1 - 2.7e-23 81.9 0.1 7.6e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.6 KPI41731.1 - 0.036 14.3 0.7 0.088 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) BTB PF00651.31 KPI41731.1 - 0.049 13.9 0.0 0.55 10.5 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain PWI PF01480.17 KPI41732.1 - 2.4e-32 111.1 0.1 5.1e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 PWI domain CSD2 PF17876.1 KPI41732.1 - 0.022 14.9 0.1 0.06 13.5 0.1 1.7 2 0 0 2 2 2 0 Cold shock domain cwf18 PF08315.12 KPI41733.1 - 1.5e-42 145.4 6.0 1.5e-42 145.4 6.0 2.0 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Spore_III_AB PF09548.10 KPI41733.1 - 0.8 9.8 4.6 0.23 11.6 1.1 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) UPF0220 PF05255.11 KPI41735.1 - 3e-64 215.6 2.0 3.8e-64 215.2 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) GATase_6 PF13522.6 KPI41736.1 - 6.5e-14 52.3 0.0 2e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KPI41736.1 - 5.4e-12 45.7 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KPI41736.1 - 1.3e-07 31.3 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KPI41736.1 - 0.00016 20.7 0.0 0.00033 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II MFS_1 PF07690.16 KPI41737.1 - 1.3e-12 47.4 21.0 1.3e-12 47.4 21.0 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily YbhQ PF11076.8 KPI41737.1 - 1 9.4 8.0 0.12 12.4 2.7 2.1 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ adh_short PF00106.25 KPI41738.1 - 4.5e-23 81.7 0.1 1.2e-22 80.3 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41738.1 - 9.4e-16 58.1 0.1 1.8e-15 57.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ScdA_N PF04405.14 KPI41738.1 - 0.11 12.2 1.2 0.25 11.0 1.2 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) ETF PF01012.21 KPI41739.1 - 2.5e-41 141.6 0.2 3e-41 141.3 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PNRC PF15365.6 KPI41740.1 - 1.4e-08 34.2 2.9 1.4e-08 34.2 2.9 3.9 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif UPRTase PF14681.6 KPI41742.1 - 1.1e-80 270.0 0.0 1.3e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KPI41742.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CN_hydrolase PF00795.22 KPI41743.1 - 1.4e-39 136.0 0.0 2e-39 135.5 0.0 1.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SUZ PF12752.7 KPI41744.1 - 4.2e-15 56.2 1.6 4.2e-15 56.2 1.6 4.2 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 KPI41744.1 - 5.4e-07 29.5 0.0 1.6e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain DUF4602 PF15375.6 KPI41746.1 - 1e-09 38.8 3.9 2.3e-09 37.7 3.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) SIMPL PF04402.14 KPI41747.1 - 3 8.2 12.2 8 6.9 12.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF541) SDH_alpha PF03313.15 KPI41748.1 - 3.1e-73 246.7 0.0 1.6e-52 178.8 0.0 2.2 1 1 1 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.15 KPI41748.1 - 3.6e-53 180.1 0.0 7e-53 179.1 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain CLPTM1 PF05602.12 KPI41749.1 - 1e-154 515.7 0.0 1.2e-154 515.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1453 PF07301.11 KPI41749.1 - 0.33 11.0 3.2 0.9 9.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) Ribosomal_S10 PF00338.22 KPI41750.1 - 7.1e-27 93.5 0.0 1.5e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ndc1_Nup PF09531.10 KPI41750.1 - 0.04 12.6 3.7 0.043 12.5 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fes1 PF08609.10 KPI41751.1 - 6.3e-26 91.1 1.7 6.3e-26 91.1 1.7 2.1 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 KPI41751.1 - 0.0004 20.7 0.4 0.0063 16.9 0.1 2.6 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KPI41751.1 - 0.00065 19.7 0.2 2.6 8.5 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KPI41751.1 - 0.022 15.2 0.6 0.32 11.6 0.1 2.8 2 1 1 3 3 3 0 HEAT-like repeat Glyco_transf_8 PF01501.20 KPI41752.1 - 3.1e-17 63.0 0.0 6.2e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 ADH_zinc_N PF00107.26 KPI41753.1 - 0.0003 20.8 0.1 0.00056 19.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI41753.1 - 0.00035 20.4 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KPI41753.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI41753.1 - 0.005 16.3 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPI41753.1 - 0.032 13.7 0.1 0.055 12.9 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KPI41753.1 - 0.091 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KPI41753.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_N_2 PF16884.5 KPI41753.1 - 0.12 12.3 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Chorismate_bind PF00425.18 KPI41754.1 - 1.4e-62 211.6 0.1 8.3e-32 110.8 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 KPI41754.1 - 3.9e-26 92.0 0.0 5.4e-25 88.3 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KPI41754.1 - 2.5e-14 53.7 0.0 5.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KPI41754.1 - 5.7e-08 32.8 0.1 4.9e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 IFRD_C PF04836.12 KPI41754.1 - 0.095 13.3 0.0 1.6 9.4 0.0 2.4 2 0 0 2 2 2 0 Interferon-related protein conserved region ACC_epsilon PF13822.6 KPI41757.1 - 0.017 15.8 0.8 0.017 15.8 0.8 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit FTZ PF03867.14 KPI41757.1 - 0.042 13.4 0.2 0.042 13.4 0.2 2.1 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region IPPT PF01715.17 KPI41758.1 - 2.4e-56 191.1 0.2 4.6e-56 190.2 0.2 1.4 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KPI41758.1 - 4.5e-06 26.2 0.1 1.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 KPI41758.1 - 8.7e-05 22.7 0.7 0.00019 21.6 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.6 KPI41758.1 - 0.00017 21.8 0.2 0.018 15.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KPI41758.1 - 0.00063 20.2 0.9 0.0024 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KPI41758.1 - 0.001 19.6 0.0 0.0025 18.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter zf-met PF12874.7 KPI41758.1 - 0.0018 18.6 0.8 0.0042 17.4 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 KPI41758.1 - 0.0022 18.5 0.1 0.055 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KPI41758.1 - 0.0027 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KPI41758.1 - 0.0043 16.8 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 KPI41758.1 - 0.0047 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 KPI41758.1 - 0.0074 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_5 PF07728.14 KPI41758.1 - 0.0095 15.9 0.1 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 KPI41758.1 - 0.011 15.2 0.2 0.03 13.8 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 KPI41758.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KPI41758.1 - 0.024 14.5 0.1 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KPI41758.1 - 0.042 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KPI41758.1 - 0.045 13.7 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain zf-C2H2_2 PF12756.7 KPI41758.1 - 0.049 14.0 1.1 0.093 13.1 1.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PPV_E1_C PF00519.17 KPI41758.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF87 PF01935.17 KPI41758.1 - 0.17 12.0 0.2 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KPI41758.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Cupin_2 PF07883.11 KPI41759.1 - 2e-07 30.6 0.2 2.5e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Sial-lect-inser PF09264.10 KPI41759.1 - 0.048 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Cupin_7 PF12973.7 KPI41759.1 - 0.048 13.6 0.0 0.065 13.2 0.0 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain PTR2 PF00854.21 KPI41760.1 - 2.6e-44 151.7 0.7 3.4e-44 151.3 0.7 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KPI41760.1 - 2.1e-08 33.5 14.7 4.7e-08 32.3 14.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41760.1 - 0.0042 16.0 9.5 0.18 10.7 2.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter CRAL_TRIO PF00650.20 KPI41761.1 - 3.2e-13 49.7 0.0 5.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Mg296 PF09644.10 KPI41761.1 - 0.033 14.3 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Mg296 protein CCDC92 PF14916.6 KPI41762.1 - 0.027 14.2 2.3 19 5.1 0.0 4.2 4 1 0 4 4 4 0 Coiled-coil domain of unknown function Nbs1_C PF08599.10 KPI41762.1 - 0.25 11.5 1.5 0.56 10.4 0.0 2.4 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Mt_ATP-synt_B PF05405.14 KPI41762.1 - 2.3 7.8 12.8 0.54 9.9 2.4 3.1 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TMF_DNA_bd PF12329.8 KPI41762.1 - 7.7 6.6 25.9 1.4 9.0 8.8 4.6 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Peptidase_A22B PF04258.13 KPI41763.1 - 2.6e-47 161.7 0.5 6.8e-47 160.3 0.5 1.7 1 0 0 1 1 1 1 Signal peptide peptidase Jagunal PF07086.12 KPI41763.1 - 0.027 14.6 0.4 8.3 6.4 0.4 2.7 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF2615 PF11027.8 KPI41763.1 - 0.14 12.4 0.1 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) FAM176 PF14851.6 KPI41763.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.8 2 1 0 2 2 2 0 FAM176 family SpoIIIAH PF12685.7 KPI41763.1 - 1.9 8.2 11.8 38 4.0 10.5 2.6 3 0 0 3 3 3 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 KPI41763.1 - 3.5 7.4 11.4 0.18 11.6 5.5 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 KPI41763.1 - 4.4 6.7 12.5 4.3 6.8 8.8 2.6 3 0 0 3 3 3 0 Translocation protein Sec62 PDDEXK_6 PF04720.12 KPI41764.1 - 0.17 11.8 0.2 0.7 9.8 0.0 1.9 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Biotin_lipoyl PF00364.22 KPI41765.1 - 7.2e-21 73.8 0.5 1.3e-20 73.0 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KPI41765.1 - 6.3e-06 26.4 0.0 2.4e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KPI41765.1 - 0.00012 21.9 0.1 0.0013 18.5 0.0 2.6 2 1 1 3 3 3 1 Biotin-lipoyl like GATA PF00320.27 KPI41767.1 - 1.5e-16 59.7 2.3 3.4e-16 58.5 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KPI41767.1 - 1.1e-11 44.4 3.8 1.9e-11 43.6 3.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Peptidase_M24 PF00557.24 KPI41768.1 - 0.044 13.5 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 Ras PF00071.22 KPI41769.1 - 1.4e-51 174.3 0.0 1.6e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI41769.1 - 1.6e-18 67.1 0.0 2.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI41769.1 - 1.8e-10 40.5 0.0 2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI41769.1 - 8.1e-07 28.8 0.1 5.9e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPI41769.1 - 0.0011 19.0 0.2 1.4 8.8 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KPI41769.1 - 0.0015 18.6 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KPI41769.1 - 0.11 11.7 0.0 9.9 5.2 0.0 2.0 1 1 0 2 2 2 0 G-protein alpha subunit An_peroxidase PF03098.15 KPI41770.1 - 1.1e-19 70.5 0.0 3.5e-17 62.2 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase Steroid_dh PF02544.16 KPI41771.1 - 1.9e-12 47.4 1.5 2.8e-11 43.6 1.5 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KPI41771.1 - 0.001 18.7 2.7 0.0023 17.5 2.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) zf-CCCH_4 PF18044.1 KPI41772.1 - 0.00025 20.7 5.3 0.00037 20.2 5.3 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KPI41772.1 - 0.001 19.7 0.0 0.0062 17.2 0.0 2.4 1 0 0 1 1 1 1 Torus domain Fez1 PF06818.15 KPI41772.1 - 0.001 19.6 93.8 0.082 13.4 17.8 5.3 1 1 4 5 5 5 3 Fez1 FlxA PF14282.6 KPI41772.1 - 0.0088 16.0 9.2 0.0088 16.0 9.2 7.6 2 1 4 7 7 5 1 FlxA-like protein zf-CCCH PF00642.24 KPI41772.1 - 0.017 15.0 1.3 0.028 14.3 1.3 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CALCOCO1 PF07888.11 KPI41772.1 - 0.023 13.6 96.0 0.015 14.2 38.8 4.2 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like MYO10_CC PF16735.5 KPI41772.1 - 0.16 12.1 27.8 0.29 11.3 0.7 7.6 4 1 2 7 7 6 0 Unconventional myosin-X coiled coil domain Abi_C PF14355.6 KPI41772.1 - 0.35 11.0 2.5 0.77 9.9 0.3 2.8 2 1 1 3 3 2 0 Abortive infection C-terminus CEP63 PF17045.5 KPI41772.1 - 0.35 10.7 85.0 0.23 11.3 38.5 4.4 1 1 2 4 4 4 0 Centrosomal protein of 63 kDa DASH_Duo1 PF08651.10 KPI41772.1 - 0.81 9.5 8.1 0.24 11.2 1.7 3.3 3 0 0 3 3 2 0 DASH complex subunit Duo1 zf_CCCH_4 PF18345.1 KPI41772.1 - 1.6 8.9 9.2 2.6 8.2 9.2 1.3 1 0 0 1 1 1 0 Zinc finger domain ERM PF00769.19 KPI41772.1 - 3.1 7.5 114.3 0.38 10.5 21.8 4.5 1 1 3 4 4 4 0 Ezrin/radixin/moesin family WD40_alt PF14077.6 KPI41772.1 - 3.5 7.6 8.6 7.6 6.5 0.1 4.8 6 0 0 6 6 3 0 Alternative WD40 repeat motif Golgin_A5 PF09787.9 KPI41772.1 - 5.6 6.3 89.1 3.1 7.2 27.5 4.8 2 2 2 4 4 4 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 KPI41772.1 - 7 6.4 92.8 0.0099 15.7 15.3 4.7 1 1 3 4 4 3 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KPI41772.1 - 7.2 7.1 112.9 0.074 13.6 7.8 7.4 1 1 6 7 7 6 0 Apg6 coiled-coil region Myosin_tail_1 PF01576.19 KPI41772.1 - 9.9 3.8 100.2 2.2 6.0 23.8 2.3 1 1 1 2 2 2 0 Myosin tail PAP2 PF01569.21 KPI41773.1 - 3.8e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily Lactamase_B_2 PF12706.7 KPI41774.1 - 2.8e-17 62.9 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI41774.1 - 1.2e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Erg28 PF03694.13 KPI41776.1 - 1.8e-15 57.3 6.0 2.2e-15 57.0 6.0 1.1 1 0 0 1 1 1 1 Erg28 like protein Piwi PF02171.17 KPI41777.1 - 6e-72 242.4 0.0 8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KPI41777.1 - 9e-21 73.3 0.2 2e-20 72.2 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KPI41777.1 - 2.5e-20 73.5 0.0 6.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KPI41777.1 - 1e-14 54.5 0.0 2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KPI41777.1 - 1e-12 48.2 0.0 2.4e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KPI41777.1 - 4.2e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute THF_DHG_CYH PF00763.23 KPI41777.1 - 0.016 15.5 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ASF1_hist_chap PF04729.13 KPI41778.1 - 4.3e-71 237.8 0.0 7.9e-71 237.0 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone PPP4R2 PF09184.11 KPI41778.1 - 5.5 6.5 14.4 8 6.0 14.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KPI41778.1 - 5.7 5.0 25.3 7.6 4.6 25.3 1.0 1 0 0 1 1 1 0 Nop14-like family FAD_binding_3 PF01494.19 KPI41779.1 - 9.7e-25 87.5 0.0 2.5e-24 86.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI41779.1 - 8.2e-13 48.7 3.4 3.2e-07 30.2 1.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI41779.1 - 4e-08 32.8 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI41779.1 - 1.3e-07 31.7 0.5 4.2e-07 30.1 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI41779.1 - 1e-06 28.3 0.6 0.0016 17.8 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPI41779.1 - 7.8e-06 26.4 0.1 0.00082 19.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI41779.1 - 9.8e-06 24.9 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI41779.1 - 2.8e-05 23.4 0.7 2.8e-05 23.4 0.7 1.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KPI41779.1 - 0.00013 21.3 0.1 0.00048 19.5 0.1 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI41779.1 - 0.0047 16.3 0.1 0.0074 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI41779.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 KPI41779.1 - 0.041 13.2 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 KPI41779.1 - 0.059 12.7 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPI41779.1 - 0.21 10.3 0.2 0.34 9.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein RrnaAD PF00398.20 KPI41779.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CBP4 PF07960.11 KPI41780.1 - 1.4e-21 76.7 0.3 1.6e-21 76.5 0.3 1.0 1 0 0 1 1 1 1 CBP4 NADH_B2 PF14813.6 KPI41781.1 - 0.01 15.6 0.2 0.012 15.4 0.2 1.3 1 1 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Hus1 PF04005.12 KPI41782.1 - 2.9e-89 299.0 0.0 3.3e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein SIR2 PF02146.17 KPI41783.1 - 1.1e-31 110.1 0.0 4.8e-12 46.2 0.0 3.2 3 0 0 3 3 3 3 Sir2 family zf-trcl PF13451.6 KPI41783.1 - 0.15 12.0 3.6 0.31 11.0 3.6 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain HypA PF01155.19 KPI41783.1 - 0.19 11.8 0.3 0.39 10.8 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PALP PF00291.25 KPI41784.1 - 1.1e-66 225.3 0.7 1.7e-66 224.7 0.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Amidohydro_1 PF01979.20 KPI41784.1 - 1.1e-24 87.4 0.1 5e-24 85.3 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI41784.1 - 4e-18 66.1 0.8 5e-09 36.1 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KPI41784.1 - 0.022 15.1 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain ADH_zinc_N PF00107.26 KPI41785.1 - 3.6e-07 30.2 0.1 5.7e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Romo1 PF10247.9 KPI41786.1 - 0.0041 17.4 0.2 2.5 8.5 0.0 2.3 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 PNPase PF03726.14 KPI41786.1 - 0.095 13.2 1.2 0.54 10.8 0.1 2.4 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Gly-zipper_Omp PF13488.6 KPI41786.1 - 5.2 7.1 7.9 8.2 6.5 1.9 2.2 2 0 0 2 2 2 0 Glycine zipper GTP_cyclohydroI PF01227.22 KPI41787.1 - 5.4e-73 244.2 0.2 7.1e-73 243.8 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KPI41787.1 - 0.0062 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Fungal_trans PF04082.18 KPI41788.1 - 1.7e-13 50.3 0.0 2.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugarporin_N PF11471.8 KPI41788.1 - 0.023 14.7 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension MgtC PF02308.16 KPI41788.1 - 0.029 14.7 0.1 0.051 13.9 0.1 1.4 1 0 0 1 1 1 0 MgtC family Ion_trans PF00520.31 KPI41789.1 - 3.2e-09 36.4 0.7 4.4e-09 35.9 0.7 1.1 1 0 0 1 1 1 1 Ion transport protein bZIP_1 PF00170.21 KPI41789.1 - 7.5e-05 22.8 0.6 0.00012 22.1 0.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KPI41789.1 - 0.085 13.5 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA MFS_1 PF07690.16 KPI41790.1 - 5.8e-39 134.0 23.1 5.8e-39 134.0 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41790.1 - 1e-13 51.0 8.6 1e-13 51.0 8.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KPI41790.1 - 4.5e-07 28.7 3.6 5.2e-07 28.5 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KPI41790.1 - 1.5e-05 23.7 3.9 2.2e-05 23.1 3.9 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.15 KPI41790.1 - 0.016 14.2 17.8 0.012 14.7 8.4 2.9 2 2 0 2 2 2 0 PUCC protein PAGK PF15284.6 KPI41790.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor Sec6 PF06046.13 KPI41792.1 - 1.8e-132 442.7 8.1 9.8e-131 436.9 3.9 2.8 2 1 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KPI41792.1 - 0.00018 20.6 2.9 0.00018 20.6 2.9 2.5 2 1 0 2 2 2 1 Vps53-like, N-terminal Dak2 PF02734.17 KPI41792.1 - 0.0047 16.9 0.7 0.066 13.1 0.1 2.6 2 0 0 2 2 2 1 DAK2 domain Nup54_C PF18437.1 KPI41792.1 - 0.041 13.8 1.1 0.14 12.0 0.3 2.4 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain DUF892 PF05974.12 KPI41792.1 - 0.1 12.6 1.3 0.25 11.4 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF892) DUF4515 PF14988.6 KPI41792.1 - 1 9.2 8.1 0.21 11.4 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) SIP1 PF04938.12 KPI41793.1 - 9.5e-13 48.4 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Secretin_N_2 PF07655.13 KPI41793.1 - 0.18 12.4 0.5 0.32 11.6 0.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Asp_Glu_race PF01177.22 KPI41794.1 - 4.6e-12 46.3 0.0 5.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 KPI41794.1 - 0.012 15.3 0.3 0.037 13.6 0.2 1.7 1 1 1 2 2 2 0 Arylmalonate decarboxylase AroM PF07302.11 KPI41794.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AroM protein Spt20 PF12090.8 KPI41794.1 - 7.8 6.0 21.7 1.7 8.2 4.3 2.1 2 0 0 2 2 2 0 Spt20 family Fungal_trans PF04082.18 KPI41795.1 - 1e-13 50.9 0.0 1.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPI41796.1 - 3.6e-72 243.7 15.2 1.1e-71 242.1 15.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41796.1 - 3.5e-17 62.4 17.4 3.5e-17 62.4 17.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI41796.1 - 0.0042 15.6 0.2 0.0042 15.6 0.2 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Polysacc_deac_1 PF01522.21 KPI41797.1 - 1e-13 51.3 0.0 2.2e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPI41797.1 - 0.002 17.8 0.0 0.0053 16.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF1178 PF06676.11 KPI41799.1 - 0.38 11.1 9.1 0.31 11.4 7.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) BNIP3 PF06553.12 KPI41799.1 - 1.3 8.7 6.0 1.5 8.5 5.9 1.2 1 1 0 1 1 1 0 BNIP3 T3SS_TC PF06511.11 KPI41799.1 - 1.7 7.9 4.9 2 7.8 4.2 1.3 1 1 0 1 1 1 0 Type III secretion systems tip complex components DNA_ligase_A_M PF01068.21 KPI41800.1 - 2.6e-23 82.7 0.0 5.1e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KPI41800.1 - 6.3e-18 65.7 0.0 1.2e-17 64.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KPI41800.1 - 0.048 14.3 0.0 0.25 12.0 0.0 2.3 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region MFS_1 PF07690.16 KPI41801.1 - 2.9e-35 121.8 27.1 2.9e-35 121.8 27.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PAM2 PF07145.15 KPI41803.1 - 1.3 8.8 5.4 0.62 9.9 0.7 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RdRP PF05183.12 KPI41804.1 - 3.9e-169 564.1 0.0 5e-169 563.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DIOX_N PF14226.6 KPI41805.1 - 8.2e-26 91.1 0.0 3e-25 89.3 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI41805.1 - 1.1e-14 54.8 0.0 2.7e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Nop10p PF04135.12 KPI41806.1 - 4.5e-20 71.4 0.9 5.3e-20 71.2 0.9 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Lipase_GDSL PF00657.22 KPI41807.1 - 2.2e-08 34.3 0.0 3.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KPI41807.1 - 1.8e-05 25.2 1.6 3e-05 24.5 0.6 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 KPI41808.1 - 9.2e-18 64.3 16.6 1.2e-17 63.9 16.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HisKA_4TM PF16926.5 KPI41808.1 - 0.091 12.3 0.4 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase DUF2304 PF10066.9 KPI41808.1 - 0.99 9.7 5.4 1.1 9.5 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) HMG_box PF00505.19 KPI41810.1 - 3.1e-06 27.5 4.0 0.0014 19.0 0.1 3.0 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KPI41810.1 - 0.00021 21.8 11.2 0.0043 17.6 0.3 3.1 3 0 0 3 3 3 2 HMG-box domain DnaA_N PF11638.8 KPI41811.1 - 0.039 13.7 0.4 1.2 9.0 0.0 3.0 3 0 0 3 3 3 0 DnaA N-terminal domain Kelch_6 PF13964.6 KPI41812.1 - 7.6e-08 32.4 10.1 5.3e-05 23.4 0.3 5.2 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KPI41812.1 - 3.8e-06 26.8 13.5 0.0044 17.0 0.5 5.7 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KPI41812.1 - 0.00023 21.4 7.3 0.046 14.0 0.2 4.6 4 1 0 4 4 4 1 Galactose oxidase, central domain TMEM51 PF15345.6 KPI41812.1 - 0.00092 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Herpes_gE PF02480.16 KPI41812.1 - 0.0083 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KPI41812.1 - 0.014 16.2 0.0 0.026 15.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KPI41812.1 - 0.022 15.4 0.2 14 6.4 0.0 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 KPI41812.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.12 KPI41812.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Kelch_1 PF01344.25 KPI41812.1 - 0.071 12.7 1.0 0.43 10.2 0.1 2.9 3 0 0 3 3 3 0 Kelch motif JmjC PF02373.22 KPI41813.1 - 1.2e-36 125.6 0.3 5e-36 123.6 0.3 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KPI41813.1 - 1.9e-19 69.9 7.4 3.8e-19 68.9 7.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KPI41813.1 - 3.3e-18 65.7 6.7 3.3e-18 65.7 6.7 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KPI41813.1 - 1.4e-06 28.2 0.0 5.4e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 jmjN domain Fungal_trans PF04082.18 KPI41815.1 - 1.2e-20 73.7 0.5 2.1e-20 72.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI41815.1 - 1.8e-05 24.7 9.0 3.6e-05 23.8 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KPI41816.1 - 2.7e-26 91.6 2.5 6e-26 90.5 2.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI41816.1 - 2.1e-20 73.0 1.5 2.6e-20 72.7 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI41816.1 - 0.00032 21.8 0.0 0.00053 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4453 PF14627.6 KPI41816.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) AlaDh_PNT_C PF01262.21 KPI41816.1 - 0.022 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hydrolase_like PF13242.6 KPI41816.1 - 0.052 13.6 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like DHHA2 PF02833.14 KPI41817.1 - 1.7e-23 83.4 0.1 2.6e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KPI41817.1 - 1.8e-08 34.6 0.0 4.4e-08 33.3 0.0 1.6 1 1 1 2 2 2 1 DHH family AA_permease_2 PF13520.6 KPI41818.1 - 2.2e-55 188.2 48.6 2.7e-55 187.9 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI41818.1 - 5.5e-21 74.7 37.9 7.4e-21 74.3 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_18 PF00704.28 KPI41819.1 - 4.9e-21 75.8 0.5 4.9e-21 75.8 0.5 2.5 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 EF-hand_4 PF12763.7 KPI41820.1 - 3e-35 120.3 0.0 2.3e-14 53.2 0.0 3.7 4 0 0 4 4 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KPI41820.1 - 2e-08 33.2 0.6 0.13 11.8 0.1 4.8 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 KPI41820.1 - 3e-08 34.0 0.0 0.00015 22.2 0.0 4.2 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KPI41820.1 - 1.8e-05 24.3 1.6 0.81 9.8 0.1 4.7 5 0 0 5 5 4 1 EF-hand domain MbeD_MobD PF04899.12 KPI41820.1 - 0.00025 21.1 15.7 0.0013 18.8 4.1 3.6 3 1 1 4 4 3 2 MbeD/MobD like Spc7 PF08317.11 KPI41820.1 - 0.00065 18.7 32.8 0.0037 16.2 22.2 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein UBA PF00627.31 KPI41820.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF3584 PF12128.8 KPI41820.1 - 0.0062 14.1 30.7 0.011 13.3 30.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PRKG1_interact PF15898.5 KPI41820.1 - 0.012 16.5 9.9 0.012 16.5 9.9 3.9 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain EF-hand_8 PF13833.6 KPI41820.1 - 0.039 13.8 0.0 26 4.8 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain pair Csm1_N PF18504.1 KPI41820.1 - 0.041 14.2 21.7 0.1 12.9 2.1 4.5 3 1 1 4 4 4 0 Csm1 N-terminal domain IFT57 PF10498.9 KPI41820.1 - 0.28 10.1 22.3 0.29 10.0 17.4 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 KPI41820.1 - 0.36 11.0 38.9 1.4 9.2 16.8 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KPI41820.1 - 0.4 11.2 37.0 2.8 8.5 12.9 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 KPI41820.1 - 0.4 10.0 32.9 0.051 12.9 14.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 KPI41820.1 - 0.47 10.8 16.4 0.16 12.3 1.9 3.1 1 1 2 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 KPI41820.1 - 0.64 10.1 16.8 0.098 12.7 5.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KPI41820.1 - 1.2 9.1 31.3 0.39 10.7 18.5 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SOGA PF11365.8 KPI41820.1 - 1.6 9.9 20.7 0.11 13.7 10.5 2.7 2 0 0 2 2 2 0 Protein SOGA Atg14 PF10186.9 KPI41820.1 - 1.7 7.7 30.1 9 5.3 8.9 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 KPI41820.1 - 2.3 6.7 34.2 0.057 12.0 26.3 2.1 2 0 0 2 2 2 0 Macoilin family AAA_13 PF13166.6 KPI41820.1 - 5.6 5.5 27.6 0.19 10.4 3.2 2.1 1 1 1 2 2 2 0 AAA domain Golgin_A5 PF09787.9 KPI41820.1 - 6.2 6.2 32.0 4.8 6.6 13.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Noelin-1 PF12308.8 KPI41820.1 - 6.6 6.8 11.2 1 9.4 1.4 2.5 1 1 0 2 2 2 0 Neurogenesis glycoprotein DUF724 PF05266.14 KPI41820.1 - 6.9 6.5 28.8 0.021 14.6 6.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Nup88 PF10168.9 KPI41820.1 - 8 4.1 22.1 11 3.6 22.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Filament PF00038.21 KPI41820.1 - 8.2 5.9 30.3 0.36 10.4 5.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF4820 PF16091.5 KPI41821.1 - 4.6 6.5 7.2 4.1 6.7 6.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) Phosphodiest PF01663.22 KPI41822.1 - 3.3e-26 92.7 0.0 4.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPI41822.1 - 0.02 14.3 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 Sulfatase Methyltransf_3 PF01596.17 KPI41823.1 - 6.3e-12 45.1 0.0 8.6e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KPI41823.1 - 1.5e-10 42.0 0.0 2.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cadherin_pro PF08758.11 KPI41823.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Cadherin prodomain like p450 PF00067.22 KPI41825.1 - 1.5e-50 172.3 0.0 3.7e-50 171.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KPI41826.1 - 8.6e-31 107.0 0.0 1.1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KPI41826.1 - 0.00085 19.2 0.0 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus PDZ_2 PF13180.6 KPI41826.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Fungal_trans PF04082.18 KPI41827.1 - 6.4e-18 64.7 1.8 1.1e-17 64.0 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NODP PF07684.12 KPI41827.1 - 0.031 14.4 0.5 0.47 10.6 0.0 2.6 2 0 0 2 2 2 0 NOTCH protein Pkinase PF00069.25 KPI41828.1 - 3.1e-55 187.4 0.1 9.6e-39 133.3 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41828.1 - 4.7e-26 91.6 0.2 1.1e-18 67.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI41828.1 - 7.9e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KPI41828.1 - 0.00033 20.1 1.1 0.0015 17.9 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KPI41828.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI41828.1 - 0.0015 18.5 0.1 0.15 11.9 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KPI41828.1 - 0.014 15.0 0.8 7.7 6.1 0.0 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PA28_alpha PF02251.18 KPI41828.1 - 0.049 13.7 0.1 0.83 9.7 0.0 2.6 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Seadorna_VP7 PF07387.11 KPI41828.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.13 KPI41828.1 - 2.2 8.2 21.6 0.57 10.1 18.3 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.27 KPI41829.1 - 9.8e-51 169.7 4.5 1.1e-17 63.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI41829.1 - 0.018 14.2 2.2 0.15 11.1 0.1 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Glyco_hydro_114 PF03537.13 KPI41830.1 - 4e-72 242.3 0.5 5.1e-72 241.9 0.5 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Amelin PF05111.12 KPI41830.1 - 0.16 11.1 3.9 0.21 10.7 3.9 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Yae1_N PF09811.9 KPI41830.1 - 2 8.2 4.4 0.57 9.9 0.5 2.1 3 0 0 3 3 3 0 Essential protein Yae1, N terminal SPC22 PF04573.12 KPI41831.1 - 1.5e-41 141.7 0.0 4.5e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Pas_Saposin PF09016.10 KPI41831.1 - 0.074 13.4 0.0 0.99 9.8 0.0 2.1 2 0 0 2 2 2 0 Pas factor saposin fold Rad9_Rad53_bind PF08605.10 KPI41832.1 - 2.7e-19 69.6 0.0 4.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 KPI41832.1 - 1.5e-18 66.4 0.1 3e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 KPI41832.1 - 6.6e-07 29.6 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KPI41832.1 - 0.00042 20.1 0.0 0.00099 19.0 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KPI41832.1 - 0.0011 19.3 0.0 0.0031 17.9 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KPI41832.1 - 0.2 11.8 0.1 3.9 7.6 0.0 3.0 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Lactamase_B PF00753.27 KPI41833.1 - 3.4e-06 27.2 0.2 6.6e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI41833.1 - 0.12 11.8 0.2 0.47 9.9 0.0 2.0 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Mito_carr PF00153.27 KPI41834.1 - 1e-25 89.5 6.8 4.3e-11 42.6 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1388 PF07142.12 KPI41835.1 - 0.031 14.2 0.2 0.063 13.2 0.2 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) RRM_1 PF00076.22 KPI41836.1 - 6.6e-56 186.0 0.0 1.7e-15 56.6 0.0 5.6 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KPI41836.1 - 0.0023 18.2 2.4 32 4.7 0.0 5.3 5 2 2 7 7 7 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KPI41836.1 - 0.0069 16.2 0.3 0.5 10.2 0.1 3.4 2 1 1 3 3 3 1 Rrp7 RRM-like N-terminal domain Spheroidin PF05541.12 KPI41836.1 - 0.021 12.7 0.0 0.029 12.2 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein RRM_occluded PF16842.5 KPI41836.1 - 0.055 13.3 0.0 0.61 10.0 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif NosL PF05573.12 KPI41836.1 - 0.058 13.7 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 NosL RecC_C PF17946.1 KPI41837.1 - 0.37 10.5 7.1 0.46 10.2 7.1 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Ribosomal_L2_C PF03947.18 KPI41838.1 - 1.4e-47 161.0 2.4 5.4e-46 155.9 2.0 2.7 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KPI41838.1 - 2.9e-24 84.8 0.8 5.2e-24 84.0 0.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain FAD_binding_3 PF01494.19 KPI41839.1 - 2.7e-53 181.5 0.0 4.8e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPI41839.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain Sugar_tr PF00083.24 KPI41840.1 - 5.2e-73 246.4 25.9 6e-73 246.2 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41840.1 - 1.3e-08 34.1 16.1 1.3e-08 34.1 16.1 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KPI41840.1 - 8.7e-05 21.2 20.3 0.0065 15.1 6.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KPI41840.1 - 0.00024 20.1 5.4 0.00024 20.1 5.4 2.2 2 0 0 2 2 2 1 MFS_1 like family SGL PF08450.12 KPI41841.1 - 0.024 14.2 0.1 0.79 9.3 0.0 2.7 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region adh_short PF00106.25 KPI41842.1 - 1.2e-17 64.1 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41842.1 - 5.2e-14 52.4 0.0 7.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41842.1 - 4.5e-07 30.0 0.0 1.1e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KPI41842.1 - 0.00031 21.0 0.1 0.00068 19.9 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KPI41842.1 - 0.0042 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0146 PF03686.13 KPI41842.1 - 0.14 12.0 0.1 0.63 9.9 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0146) ADH_N PF08240.12 KPI41843.1 - 4.4e-30 103.8 0.9 9e-30 102.8 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI41843.1 - 1.9e-17 63.5 0.6 2.9e-17 62.9 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI41843.1 - 5.7e-10 40.4 0.0 1.2e-09 39.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPI41843.1 - 0.0067 15.7 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IGFBP PF00219.18 KPI41843.1 - 0.095 13.4 1.0 0.095 13.4 1.0 2.0 2 0 0 2 2 2 0 Insulin-like growth factor binding protein SKIP_SNW PF02731.15 KPI41844.1 - 7.6e-71 237.0 6.1 7.6e-71 237.0 6.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Iron_permease PF04120.12 KPI41844.1 - 3.1 7.6 4.7 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Low affinity iron permease p450 PF00067.22 KPI41845.1 - 2.4e-51 174.9 0.0 3.3e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Podoplanin PF05808.11 KPI41846.1 - 1.1e-05 25.5 2.0 2.2e-05 24.6 2.0 1.4 1 0 0 1 1 1 1 Podoplanin CYYR1 PF10873.8 KPI41846.1 - 0.021 15.3 2.2 0.021 15.3 2.2 2.3 1 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 VSP PF03302.13 KPI41846.1 - 0.03 13.2 1.7 0.044 12.6 1.7 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Phage_holin_2_4 PF16082.5 KPI41846.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Amnionless PF14828.6 KPI41846.1 - 0.26 10.0 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Rab5ip PF07019.12 KPI41846.1 - 0.69 10.5 2.9 1.5 9.4 2.9 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DAGK_cat PF00781.24 KPI41847.1 - 2.5e-25 88.5 0.0 3.9e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NmrA PF05368.13 KPI41848.1 - 5.8e-05 22.8 0.0 9.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF5520 PF17658.1 KPI41848.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) AA_permease PF00324.21 KPI41849.1 - 5.1e-107 358.4 43.8 1.6e-106 356.8 43.8 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI41849.1 - 4.1e-23 81.9 44.4 5.4e-21 74.9 44.4 2.0 1 1 0 1 1 1 1 Amino acid permease FlgN PF05130.12 KPI41850.1 - 0.033 14.7 0.1 0.039 14.5 0.1 1.1 1 0 0 1 1 1 0 FlgN protein CdvA PF18822.1 KPI41850.1 - 0.044 13.6 0.1 0.052 13.4 0.1 1.1 1 0 0 1 1 1 0 CdvA-like coiled-coil domain WD40 PF00400.32 KPI41851.1 - 3.1e-25 87.9 10.5 1.1e-05 26.0 0.2 6.9 7 0 0 7 7 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI41851.1 - 2e-12 47.2 0.7 0.0016 18.7 0.1 5.4 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KPI41851.1 - 0.003 17.4 0.3 11 6.1 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KPI41851.1 - 0.0055 16.3 0.0 0.048 13.2 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 KPI41851.1 - 0.013 14.5 0.1 0.054 12.5 0.1 2.1 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KPI41851.1 - 0.015 14.7 0.1 0.39 10.0 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KPI41851.1 - 0.045 13.1 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain SGL PF08450.12 KPI41851.1 - 0.069 12.7 0.0 3.8 7.0 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region DPPIV_N PF00930.21 KPI41851.1 - 0.081 11.7 0.1 0.36 9.5 0.1 2.2 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.16 KPI41851.1 - 0.1 11.1 0.0 0.44 9.0 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 KPI41851.1 - 0.12 12.3 0.2 9 6.1 0.1 3.0 2 2 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A PUF PF00806.19 KPI41853.1 - 2.1e-58 190.8 8.0 5e-09 35.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat p450 PF00067.22 KPI41854.1 - 5.8e-63 213.2 0.0 7.7e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KPI41855.1 - 0.0016 18.1 0.2 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold EHN PF06441.12 KPI41855.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Aldolase_II PF00596.21 KPI41856.1 - 1.2e-51 175.3 0.6 1.8e-51 174.8 0.6 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HRI1 PF16815.5 KPI41857.1 - 4e-32 111.8 0.1 4.9e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 MFS_1 PF07690.16 KPI41859.1 - 7.8e-26 90.8 34.5 1.2e-25 90.2 34.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_B561 PF03188.16 KPI41859.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.7 3 1 1 4 4 4 0 Eukaryotic cytochrome b561 Phage_holin_5_2 PF16079.5 KPI41859.1 - 2.6 8.4 7.5 0.21 11.9 1.1 2.7 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V QueT PF06177.11 KPI41859.1 - 8.3 6.8 21.0 0.064 13.6 8.7 2.9 2 1 1 3 3 3 0 QueT transporter Aminotran_5 PF00266.19 KPI41860.1 - 5.1e-21 75.1 0.0 6.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.25 KPI41862.1 - 1.7e-05 24.4 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Transp_cyt_pur PF02133.15 KPI41863.1 - 8e-96 321.5 38.1 9.2e-96 321.3 38.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TcA_TcB_BD PF18276.1 KPI41866.1 - 2e-83 279.8 0.1 4e-81 272.3 0.0 2.3 1 1 1 2 2 2 2 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 KPI41866.1 - 1.3e-20 73.7 0.2 2.9e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 Neuraminidase-like domain VRP1 PF03538.14 KPI41866.1 - 0.003 17.0 0.3 0.14 11.5 0.3 2.3 1 1 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein PaO PF08417.12 KPI41866.1 - 0.021 15.0 0.0 0.068 13.3 0.0 1.8 1 0 0 1 1 1 0 Pheophorbide a oxygenase TerB PF05099.13 KPI41866.1 - 0.022 14.7 4.6 16 5.5 0.0 4.2 4 0 0 4 4 4 0 Tellurite resistance protein TerB 2-Hacid_dh_C PF02826.19 KPI41867.1 - 1.4e-57 194.0 0.0 1.7e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI41867.1 - 1.6e-19 69.9 0.0 1.8e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI41867.1 - 3.7e-07 30.4 0.0 1.8e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KPI41867.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KPI41867.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KPI41868.1 - 4.3e-15 55.5 24.9 3.7e-13 49.1 24.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily CPDase PF07823.11 KPI41869.1 - 7.5e-33 113.9 0.0 8.5e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KPI41869.1 - 0.0011 18.9 0.0 0.28 11.1 0.0 2.1 1 1 0 2 2 2 2 2'-5' RNA ligase superfamily NAAA-beta PF15508.6 KPI41870.1 - 4.5e-11 42.9 0.1 8.1e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase p450 PF00067.22 KPI41872.1 - 3e-50 171.3 0.0 4e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Baculo_PEP_C PF04513.12 KPI41873.1 - 0.00013 22.0 10.1 0.0019 18.3 10.0 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-ZPR1 PF03367.13 KPI41873.1 - 0.04 13.8 6.1 2.3 8.0 0.4 3.3 1 1 3 4 4 4 0 ZPR1 zinc-finger domain DUF3493 PF11998.8 KPI41873.1 - 0.14 12.3 0.5 0.4 10.9 0.5 1.8 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 Perilipin PF03036.16 KPI41873.1 - 0.22 10.5 5.3 0.28 10.2 5.3 1.2 1 0 0 1 1 1 0 Perilipin family Lambda_Bor PF06291.11 KPI41873.1 - 2.3 8.3 5.8 2.5 8.2 0.4 2.8 2 1 1 3 3 3 0 Bor protein GFO_IDH_MocA PF01408.22 KPI41874.1 - 5.6e-16 59.5 0.3 1.1e-15 58.5 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI41874.1 - 7e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Lipocalin_2 PF08212.12 KPI41874.1 - 4.3e-07 30.0 0.0 7.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain B12-binding PF02310.19 KPI41874.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain TPR_14 PF13428.6 KPI41875.1 - 1.1e-25 88.2 29.8 0.0041 17.8 0.3 11.8 9 2 3 12 12 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 KPI41875.1 - 3e-24 85.3 7.0 7.6e-06 26.4 0.0 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat HAT PF02184.16 KPI41875.1 - 3.2e-23 81.4 81.3 2.8e-15 56.0 3.7 13.5 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat Suf PF05843.14 KPI41875.1 - 3.6e-11 43.6 28.2 0.017 15.1 5.0 7.2 2 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KPI41875.1 - 2.2e-10 40.2 11.4 0.091 13.2 0.0 8.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI41875.1 - 1.1e-08 34.6 19.4 0.73 10.2 0.0 9.9 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI41875.1 - 1.9e-08 33.8 29.3 0.36 11.0 0.0 10.2 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KPI41875.1 - 2.2e-08 34.2 24.2 1.2 9.9 0.0 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI41875.1 - 3e-06 27.8 27.3 0.13 13.0 0.0 8.7 9 2 2 11 11 11 4 Tetratricopeptide repeat TPR_15 PF13429.6 KPI41875.1 - 8.5e-05 21.9 20.9 0.093 11.9 4.0 6.2 1 1 3 6 6 6 2 Tetratricopeptide repeat RAB3GAP2_C PF14656.6 KPI41875.1 - 0.00054 18.3 0.1 0.00085 17.7 0.1 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus NRDE-2 PF08424.10 KPI41875.1 - 0.0012 18.0 19.4 0.0077 15.4 0.7 5.1 3 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 KPI41875.1 - 0.02 15.0 14.1 3.1 8.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI41875.1 - 0.12 12.6 7.5 4.2 7.7 0.0 5.1 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KPI41875.1 - 0.24 11.7 30.4 1.6 9.1 0.2 9.1 11 1 0 11 11 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI41875.1 - 0.62 10.0 14.8 41 4.2 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPI41875.1 - 1.9 8.6 18.9 6.6 6.9 1.0 6.7 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat HATPase_c PF02518.26 KPI41876.1 - 5.3e-22 78.4 0.1 1.1e-21 77.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI41876.1 - 1.2e-16 60.8 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KPI41876.1 - 3.6e-13 49.4 0.0 1.3e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.24 KPI41877.1 - 1.2e-74 251.8 21.5 1.4e-74 251.7 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41877.1 - 5.6e-23 81.4 26.4 5.6e-23 81.4 26.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TraP PF07296.11 KPI41877.1 - 0.013 14.6 0.8 0.31 10.2 0.1 2.2 2 0 0 2 2 2 0 TraP protein DUF5504 PF17608.2 KPI41877.1 - 0.89 9.7 7.0 2.8 8.1 1.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5504) ThrE PF06738.12 KPI41877.1 - 9.2 5.5 12.8 0.066 12.6 3.1 2.2 2 0 0 2 2 2 0 Putative threonine/serine exporter zf-RING_11 PF17123.5 KPI41879.1 - 0.11 12.3 1.1 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger QRPTase_C PF01729.19 KPI41880.1 - 1.4e-55 187.7 0.0 2.3e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KPI41880.1 - 3e-18 65.6 0.0 1e-17 64.0 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.22 KPI41880.1 - 0.016 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PHB_depo_C PF06850.11 KPI41880.1 - 0.054 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Acyl_transf_1 PF00698.21 KPI41881.1 - 8.5e-12 45.2 0.0 2.1e-10 40.6 0.0 2.0 1 1 0 2 2 2 2 Acyl transferase domain Adaptin_N PF01602.20 KPI41882.1 - 1.5e-93 314.2 6.2 2.2e-93 313.6 6.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KPI41882.1 - 3.8e-58 195.4 0.6 1e-57 193.9 0.6 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KPI41882.1 - 8.7e-56 187.4 0.0 2.8e-55 185.7 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KPI41882.1 - 2.1e-13 50.6 4.1 1.4e-09 38.2 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPI41882.1 - 9.8e-11 41.9 2.2 1.4e-07 31.8 0.2 5.5 3 1 3 6 6 6 2 HEAT repeats HEAT PF02985.22 KPI41882.1 - 8.8e-05 22.4 0.2 0.1 12.9 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat Coatomer_g_Cpla PF16381.5 KPI41882.1 - 0.00022 21.3 0.0 0.00071 19.7 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform API5 PF05918.11 KPI41882.1 - 0.0021 16.9 6.3 0.044 12.6 0.1 3.0 3 0 0 3 3 3 2 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.6 KPI41882.1 - 0.0036 17.8 1.7 0.21 12.1 0.2 3.8 3 1 2 5 5 4 2 HEAT-like repeat HEAT_PBS PF03130.16 KPI41882.1 - 0.016 15.9 0.7 26 5.9 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF5578 PF17741.1 KPI41882.1 - 0.02 14.3 3.2 2.1 7.7 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5578) DNA_alkylation PF08713.11 KPI41882.1 - 0.035 13.8 0.2 0.33 10.6 0.0 2.6 2 1 1 3 3 3 0 DNA alkylation repair enzyme DUF4495 PF14906.6 KPI41882.1 - 0.052 12.6 0.1 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) Arm PF00514.23 KPI41882.1 - 1.8 8.7 7.0 2.3 8.4 0.1 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SelB-wing_1 PF09105.10 KPI41883.1 - 0.088 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Cu_bind_like PF02298.17 KPI41884.1 - 8.6e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Plastocyanin-like domain Cas_csx3 PF09620.10 KPI41884.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cupredoxin_1 PF13473.6 KPI41884.1 - 0.025 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain Cyclase PF04199.13 KPI41885.1 - 1.2e-10 41.8 0.0 1.5e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 KPI41885.1 - 0.013 15.1 0.1 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) HMG_box PF00505.19 KPI41885.1 - 0.018 15.5 0.2 0.04 14.3 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Cyt-b5 PF00173.28 KPI41886.1 - 1.5e-09 37.8 0.1 1.8e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DOG1 PF14144.6 KPI41887.1 - 0.036 14.3 0.1 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Seed dormancy control TTRAP PF14203.6 KPI41887.1 - 0.16 11.9 2.6 0.35 10.9 1.4 2.0 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein CN_hydrolase PF00795.22 KPI41888.1 - 5.7e-30 104.5 0.0 1.5e-29 103.2 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KPI41888.1 - 1.3e-18 67.0 0.0 1.1e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 NAD synthase DUF4148 PF13663.6 KPI41888.1 - 0.037 14.2 0.4 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) SNF2_N PF00176.23 KPI41889.1 - 8.6e-43 146.4 0.6 8e-41 139.9 0.6 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KPI41889.1 - 2.8e-23 81.5 7.2 1.7e-15 56.6 3.8 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KPI41889.1 - 1.3e-18 67.4 0.0 3.1e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KPI41889.1 - 3.8e-18 65.7 0.5 2e-17 63.4 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Cdh1_DBD_1 PF18196.1 KPI41889.1 - 7.4e-06 26.3 4.1 2.3e-05 24.7 0.8 5.3 5 1 1 6 6 6 2 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 KPI41889.1 - 0.046 13.9 0.8 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain EspA PF03433.13 KPI41889.1 - 0.068 13.0 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 EspA-like secreted protein ECH_1 PF00378.20 KPI41890.1 - 6.3e-40 137.1 0.0 1.3e-39 136.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 KPI41890.1 - 5.7e-39 134.3 0.0 1e-38 133.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ECH_2 PF16113.5 KPI41890.1 - 1.2e-19 71.0 0.2 2.5e-19 70.0 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase EMP24_GP25L PF01105.24 KPI41891.1 - 2e-45 155.0 1.6 2.3e-45 154.8 1.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA_int_endo PF01974.17 KPI41892.1 - 9.4e-20 70.5 0.2 2.7e-19 69.0 0.2 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KPI41892.1 - 1e-05 25.1 0.1 0.0024 17.5 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Rxt3 PF08642.10 KPI41892.1 - 0.13 13.0 0.3 20 6.0 0.1 3.0 3 1 0 3 3 3 0 Histone deacetylation protein Rxt3 DUF1168 PF06658.12 KPI41892.1 - 8.4 6.2 13.3 0.11 12.3 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Sugar_tr PF00083.24 KPI41893.1 - 1.3e-105 353.9 20.2 1.6e-105 353.6 20.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI41893.1 - 1.1e-24 87.1 27.5 1.1e-24 87.1 27.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI41893.1 - 2.7e-08 32.7 6.5 5e-08 31.8 6.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KPI41893.1 - 0.0011 17.9 0.2 0.0011 17.9 0.2 3.0 2 1 1 3 3 3 1 MFS_1 like family LacY_symp PF01306.19 KPI41893.1 - 0.0091 14.8 4.7 0.024 13.4 1.1 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter Roughex PF06020.11 KPI41894.1 - 0.97 8.5 11.7 1.9 7.5 11.7 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 KPI41894.1 - 8.4 4.8 17.8 0.71 8.4 7.7 2.1 2 0 0 2 2 2 0 Macoilin family Neur_chan_memb PF02932.16 KPI41894.1 - 9.8 6.2 8.1 2.4 8.2 3.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_43 PF04616.14 KPI41895.1 - 9.1e-87 291.0 2.9 4.6e-65 219.8 1.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KPI41895.1 - 1.4e-43 149.0 0.0 1.9e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PhyH PF05721.13 KPI41896.1 - 1.1e-23 84.7 0.1 1.6e-23 84.1 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Abhydrolase_1 PF00561.20 KPI41897.1 - 1.6e-18 67.3 0.1 3.4e-18 66.2 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI41897.1 - 1.9e-12 47.2 0.0 4.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF4078 PF13300.6 KPI41898.1 - 2.5e-26 91.8 15.0 2.5e-26 91.8 15.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) Sugar_tr PF00083.24 KPI41899.1 - 4.5e-69 233.5 12.6 1.4e-41 142.8 1.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI41899.1 - 7.4e-19 67.9 44.3 1.4e-17 63.7 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_racemase PF05544.11 KPI41900.1 - 3.5e-55 187.3 0.0 2.1e-54 184.8 0.0 2.0 1 1 0 1 1 1 1 Proline racemase Methyltransf_34 PF11312.8 KPI41900.1 - 0.13 11.5 0.0 9.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase MARVEL PF01284.23 KPI41901.1 - 8.9e-16 58.2 8.9 1.3e-15 57.7 8.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2417 PF10329.9 KPI41901.1 - 0.063 12.7 1.8 0.12 11.8 1.8 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Myb_DNA-bind_6 PF13921.6 KPI41902.1 - 0.00078 19.7 0.0 0.0039 17.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KPI41902.1 - 0.046 13.9 0.3 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain FYRC PF05965.14 KPI41902.1 - 0.097 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus DEC-1_N PF04625.13 KPI41903.1 - 0.97 8.4 3.8 0.32 10.0 0.8 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region AAA PF00004.29 KPI41904.1 - 1.8e-14 54.3 0.0 5.5e-14 52.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KPI41904.1 - 2.6e-11 43.9 0.5 4.7e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.6 KPI41904.1 - 0.0016 18.9 0.4 0.0078 16.6 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain CENP-B_dimeris PF09026.10 KPI41904.1 - 0.0022 18.4 0.4 0.04 14.3 0.2 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain IstB_IS21 PF01695.17 KPI41904.1 - 0.049 13.4 0.1 0.24 11.1 0.0 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 KPI41904.1 - 0.049 14.1 0.4 0.29 11.6 0.1 2.6 2 1 0 2 2 2 0 ABC transporter KTI12 PF08433.10 KPI41904.1 - 0.067 12.6 0.9 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 KPI41904.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.13 KPI41904.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KPI41904.1 - 0.11 12.6 0.3 0.26 11.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KPI41904.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KPI41904.1 - 0.17 12.4 0.0 0.44 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Methyltransf_2 PF00891.18 KPI41905.1 - 2.6e-11 43.2 0.0 2.9e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain CN_hydrolase PF00795.22 KPI41906.1 - 6e-35 120.8 0.0 8.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 KPI41907.1 - 6.6e-07 29.0 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41907.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase DIT1_PvcA PF05141.12 KPI41908.1 - 1e-70 238.4 0.1 8.8e-69 232.0 0.1 2.1 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.16 KPI41909.1 - 2.5e-37 128.6 38.1 2.5e-37 128.6 38.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI41909.1 - 1.1e-05 24.9 8.8 1.1e-05 24.9 8.8 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MR_MLE_C PF13378.6 KPI41910.1 - 7.4e-50 169.6 0.0 1.1e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI41910.1 - 2e-06 28.0 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain FAD_binding_3 PF01494.19 KPI41911.1 - 3.4e-21 75.9 0.8 1.5e-20 73.8 0.8 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI41911.1 - 3e-06 26.7 0.6 0.0061 15.8 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI41911.1 - 2.6e-05 23.7 0.3 0.004 16.5 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI41911.1 - 0.00027 21.1 0.4 0.00076 19.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI41911.1 - 0.011 14.8 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 KPI41911.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 KPI41911.1 - 0.059 12.4 1.2 4 6.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 KPI41911.1 - 0.06 12.9 5.9 0.22 11.1 5.4 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase PFO_beta_C PF12367.8 KPI41911.1 - 0.14 12.3 0.0 29 4.9 0.0 2.5 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal CAT_RBD PF03123.15 KPI41911.1 - 0.2 11.6 1.2 8.7 6.4 0.0 2.9 3 0 0 3 3 3 0 CAT RNA binding domain NAD_binding_9 PF13454.6 KPI41911.1 - 0.23 11.4 3.8 3 7.8 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI41911.1 - 0.24 10.6 0.9 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KPI41911.1 - 0.76 9.6 2.4 1.4 8.8 2.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPI41911.1 - 1 8.0 3.0 2.3 6.8 3.0 1.6 1 1 0 1 1 1 0 HI0933-like protein COesterase PF00135.28 KPI41912.1 - 4.8e-62 210.5 0.0 9e-62 209.6 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI41912.1 - 2.5e-08 34.1 2.3 0.0003 20.7 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI41912.1 - 5.5e-06 26.0 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KPI41912.1 - 0.00062 19.5 0.2 0.0015 18.2 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KPI41912.1 - 0.042 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KPI41912.1 - 0.062 12.1 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Steryl acetyl hydrolase Pkinase PF00069.25 KPI41913.1 - 9.2e-52 176.0 0.0 3.1e-45 154.6 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI41913.1 - 1.4e-27 96.6 0.0 7.2e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KPI41913.1 - 0.00053 20.0 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KPI41913.1 - 0.0053 15.6 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KPI41913.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KPI41913.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ATP-synt_ab PF00006.25 KPI41915.1 - 8.2e-70 234.8 0.0 4.8e-52 176.7 0.0 2.2 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KPI41915.1 - 8.3e-46 154.8 0.1 1.6e-45 153.9 0.1 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KPI41915.1 - 2.3e-14 53.7 0.4 4.3e-14 52.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Topoisom_bac PF01131.20 KPI41916.1 - 3e-91 306.5 0.0 4.1e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KPI41916.1 - 5.3e-21 74.8 0.0 1.4e-19 70.2 0.0 2.6 3 0 0 3 3 3 1 Toprim domain RNA_pol_Rpb2_6 PF00562.28 KPI41917.1 - 5.4e-125 417.5 0.1 7.6e-125 417.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KPI41917.1 - 6.6e-49 166.2 0.0 1.6e-48 164.9 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KPI41917.1 - 4.7e-27 94.9 0.3 1e-26 93.7 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KPI41917.1 - 2.8e-25 88.5 0.3 7.7e-25 87.1 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KPI41917.1 - 2.7e-24 85.2 0.1 6.1e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KPI41917.1 - 2.3e-18 66.1 0.0 4.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KPI41917.1 - 8.2e-10 39.1 0.4 2.7e-09 37.4 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 adh_short PF00106.25 KPI41918.1 - 3e-22 79.1 0.2 3.8e-22 78.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41918.1 - 2.8e-17 63.1 0.1 4e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41918.1 - 2.4e-05 24.3 0.2 2.9e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI41918.1 - 0.0015 18.4 0.4 0.099 12.5 0.1 2.3 2 1 0 2 2 2 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 KPI41918.1 - 0.073 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_tran PF00005.27 KPI41919.1 - 9e-36 123.4 0.0 1.3e-17 64.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI41919.1 - 2.2e-12 46.9 1.2 0.00094 18.7 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KPI41919.1 - 1.3e-11 44.9 5.8 0.017 14.9 0.0 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KPI41919.1 - 1.1e-05 25.9 0.0 0.022 15.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI41919.1 - 2.6e-05 24.7 0.0 0.13 12.6 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KPI41919.1 - 3.1e-05 24.0 0.1 0.027 14.4 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KPI41919.1 - 5.1e-05 23.2 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KPI41919.1 - 6.9e-05 22.7 2.0 0.21 11.3 0.0 3.3 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KPI41919.1 - 0.00011 22.5 0.0 0.025 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPI41919.1 - 0.00044 20.8 0.0 1.4 9.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_13 PF13166.6 KPI41919.1 - 0.00069 18.4 0.0 0.00069 18.4 0.0 2.3 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 KPI41919.1 - 0.00074 19.3 0.5 0.17 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KPI41919.1 - 0.00076 19.2 0.7 0.79 9.4 0.0 3.3 3 0 0 3 3 3 1 Thymidylate kinase AAA_29 PF13555.6 KPI41919.1 - 0.00077 19.2 0.8 0.53 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NB-ARC PF00931.22 KPI41919.1 - 0.0012 18.1 0.1 0.2 10.8 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain RNA_helicase PF00910.22 KPI41919.1 - 0.0021 18.4 0.1 1 9.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KPI41919.1 - 0.0039 17.4 0.6 0.87 9.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPI41919.1 - 0.0052 17.1 1.4 0.52 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KPI41919.1 - 0.0052 16.3 0.1 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KPI41919.1 - 0.0071 16.9 1.0 1 9.8 0.5 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KPI41919.1 - 0.0077 15.9 3.2 0.16 11.6 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TsaE PF02367.17 KPI41919.1 - 0.0094 16.0 0.1 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KPI41919.1 - 0.014 15.3 1.5 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 KPI41919.1 - 0.027 13.8 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RLI PF04068.15 KPI41919.1 - 0.042 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_30 PF13604.6 KPI41919.1 - 0.047 13.4 0.8 3.2 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KPI41919.1 - 0.055 13.5 0.1 8.8 6.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KPI41919.1 - 0.068 13.2 0.4 3.1 7.8 0.1 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) VirE PF05272.11 KPI41919.1 - 0.07 12.9 0.0 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E ATPase PF06745.13 KPI41919.1 - 0.098 12.0 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 KPI41919.1 - 0.15 11.8 2.5 0.17 11.6 0.0 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 KPI41919.1 - 0.16 12.2 0.0 13 6.1 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KPI41919.1 - 0.19 11.9 0.9 24 5.1 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KPI41919.1 - 1 9.2 3.3 19 5.1 0.1 3.0 3 0 0 3 3 3 0 NTPase Abhydrolase_6 PF12697.7 KPI41920.1 - 3.7e-12 47.3 0.0 4.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KPI41920.1 - 2.1e-06 27.5 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KPI41920.1 - 1.6e-05 24.3 0.0 3.9e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPI41920.1 - 1.9e-05 24.9 0.0 4.7e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain LCAT PF02450.15 KPI41920.1 - 7.4e-05 22.1 0.0 0.0006 19.1 0.0 1.9 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KPI41920.1 - 0.0026 17.4 0.0 0.0076 15.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KPI41920.1 - 0.0048 16.6 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.12 KPI41920.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.25 KPI41920.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KPI41920.1 - 0.093 11.6 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Gcd10p PF04189.13 KPI41923.1 - 6e-117 390.0 0.0 1.2e-116 389.1 0.0 1.4 2 0 0 2 2 2 1 Gcd10p family REV PF00424.18 KPI41923.1 - 0.015 15.3 0.2 0.35 10.9 0.1 2.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Aldedh PF00171.22 KPI41925.1 - 5.7e-172 572.4 0.4 6.4e-172 572.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI41925.1 - 0.08 12.4 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) MFS_1 PF07690.16 KPI41926.1 - 5.5e-41 140.7 45.9 5.5e-41 140.7 45.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI41926.1 - 5.6e-10 38.3 17.7 7.4e-10 37.9 17.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MGC-24 PF05283.11 KPI41926.1 - 0.43 11.0 2.0 0.79 10.2 2.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CrgA PF06781.12 KPI41926.1 - 3.1 7.9 8.0 7.6 6.7 0.0 3.5 4 0 0 4 4 4 0 Cell division protein CrgA Fungal_trans_2 PF11951.8 KPI41927.1 - 7.6e-23 80.9 2.2 9.3e-23 80.7 2.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Questin_oxidase PF14027.6 KPI41929.1 - 5.2e-92 309.0 0.0 6.4e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF2967 PF11179.8 KPI41930.1 - 0.018 13.2 8.3 0.035 12.2 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) SpvB PF03534.13 KPI41931.1 - 2.1e-108 361.9 0.2 3.5e-108 361.2 0.2 1.4 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 KPI41931.1 - 1.5e-38 131.9 2.1 4.8e-30 104.2 0.0 6.8 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 KPI41931.1 - 2.1e-31 109.0 0.6 5.2e-31 107.7 0.6 1.8 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 KPI41931.1 - 3.9e-11 43.4 11.7 0.00048 20.7 0.5 5.2 5 0 0 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.14 KPI41931.1 - 0.00052 20.5 50.2 0.1 13.1 1.3 12.1 11 1 1 12 12 12 3 RHS Repeat Mu-transpos_C PF09299.11 KPI41931.1 - 0.17 11.8 0.1 0.59 10.1 0.1 1.9 1 0 0 1 1 1 0 Mu transposase, C-terminal zf-MYND PF01753.18 KPI41932.1 - 2.2e-09 37.2 16.8 3.9e-09 36.5 16.8 1.4 1 0 0 1 1 1 1 MYND finger OMS28_porin PF03532.13 KPI41932.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 OMS28 porin Rhodanese_C PF12368.8 KPI41932.1 - 0.18 12.2 4.7 0.35 11.3 4.7 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal DUF1749 PF08538.10 KPI41933.1 - 3.4e-63 213.5 0.0 4.3e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) adh_short PF00106.25 KPI41934.1 - 3.5e-25 88.6 0.1 7.6e-25 87.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI41934.1 - 8e-18 64.8 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI41934.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KPI41935.1 - 3e-19 69.1 1.9 2.6e-09 36.4 0.7 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF3645 PF12359.8 KPI41935.1 - 0.12 11.8 0.2 0.25 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) DUF1223 PF06764.11 KPI41937.1 - 1.4e-47 162.3 0.0 1.8e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) DUF5349 PF17298.2 KPI41938.1 - 1.5 8.5 8.3 1.9 8.2 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) FMO-like PF00743.19 KPI41939.1 - 1.3e-15 56.9 0.1 3.9e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI41939.1 - 2.7e-14 53.1 0.0 5.9e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI41939.1 - 3.7e-11 42.8 0.0 5.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI41939.1 - 6.4e-10 38.7 0.0 3e-08 33.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI41939.1 - 7.1e-09 35.8 0.0 2.4e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI41939.1 - 0.00021 20.7 0.0 0.00052 19.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KPI41939.1 - 0.00021 20.5 0.0 0.00065 18.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI41939.1 - 0.0044 15.8 0.0 0.034 12.9 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KPI41939.1 - 0.018 14.2 0.1 0.085 11.9 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KPI41939.1 - 0.018 15.6 0.0 10 6.8 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI41939.1 - 0.029 14.4 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KPI41939.1 - 0.06 12.9 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI41939.1 - 0.068 12.2 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KPI41940.1 - 1.9e-28 100.1 9.8 2.1e-27 96.7 9.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KPI41940.1 - 0.023 14.0 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Fungal_trans_2 PF11951.8 KPI41942.1 - 9.4e-05 21.4 0.6 0.0061 15.4 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Arginase PF00491.21 KPI41943.1 - 2.2e-72 243.9 0.3 5.7e-71 239.3 0.3 2.0 1 1 0 1 1 1 1 Arginase family CAP_GLY PF01302.25 KPI41945.1 - 3e-17 62.4 0.0 5.5e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KPI41945.1 - 4.5e-12 46.0 20.8 0.00011 22.5 0.4 6.6 6 1 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KPI41945.1 - 4.7e-06 26.2 12.2 0.044 13.8 1.1 6.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 KPI41945.1 - 2.5e-05 23.9 19.8 0.0041 16.9 6.6 5.5 4 2 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 KPI41945.1 - 0.0034 16.9 3.8 0.7 9.4 0.2 4.0 2 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 KPI41945.1 - 0.31 11.8 14.1 16 6.6 0.3 6.1 6 2 0 6 6 6 0 Leucine Rich Repeat BTB PF00651.31 KPI41946.1 - 0.0099 16.1 0.0 0.081 13.2 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain GlpM PF06942.12 KPI41946.1 - 1 9.8 2.7 2.4 8.6 0.1 2.6 3 0 0 3 3 3 0 GlpM protein Fungal_trans PF04082.18 KPI41947.1 - 1.2e-08 34.3 2.0 2e-08 33.6 1.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI41948.1 - 1.4e-29 103.1 27.9 2.1e-29 102.6 27.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CM2 PF03021.14 KPI41948.1 - 0.15 11.8 0.4 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 Influenza C virus M2 protein HLH PF00010.26 KPI41949.1 - 4.1e-09 36.2 0.0 1.5e-08 34.5 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain FlaC_arch PF05377.11 KPI41949.1 - 0.14 12.5 1.4 0.28 11.6 0.4 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MRC1 PF09444.10 KPI41949.1 - 0.56 10.7 7.9 0.042 14.4 3.0 1.5 2 0 0 2 2 2 0 MRC1-like domain Trimer_CC PF08954.11 KPI41949.1 - 1.3 8.6 4.4 23 4.7 0.0 3.3 3 0 0 3 3 3 0 Trimerisation motif Abhydrolase_6 PF12697.7 KPI41950.1 - 4.3e-08 34.0 0.0 8.7e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KPI41950.1 - 0.0037 16.9 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KPI41950.1 - 0.02 15.0 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KPI41950.1 - 0.028 14.1 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 KPI41950.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase Frataxin_Cyay PF01491.16 KPI41951.1 - 3.7e-33 113.8 0.1 4.5e-32 110.3 0.1 2.1 1 1 0 1 1 1 1 Frataxin-like domain DUF1176 PF06674.11 KPI41951.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Fungal_trans PF04082.18 KPI41952.1 - 1.1e-21 77.1 0.0 2.1e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI41952.1 - 1e-08 35.1 11.7 2.3e-08 34.0 11.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KPI41954.1 - 1.3e-26 93.7 3.9 2e-26 93.0 3.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI41954.1 - 8.4e-22 78.0 0.0 1.8e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI41954.1 - 1.1e-18 67.2 0.0 2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI41954.1 - 6.7e-09 36.1 2.1 1.1e-08 35.4 2.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 KPI41954.1 - 0.024 15.1 0.0 0.067 13.7 0.0 1.8 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cys_Met_Meta_PP PF01053.20 KPI41955.1 - 7e-149 495.5 0.0 8e-149 495.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPI41955.1 - 4.3e-10 39.4 0.1 6.8e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KPI41955.1 - 7.9e-10 38.4 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI41955.1 - 2.6e-09 36.5 0.1 4e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPI41955.1 - 3.2e-06 26.7 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KPI41955.1 - 0.00053 18.6 0.0 0.0007 18.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KPI41955.1 - 0.00088 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Asparaginase_C PF17763.1 KPI41955.1 - 0.024 14.8 0.0 0.065 13.5 0.0 1.7 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 KPI41955.1 - 0.03 13.0 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS CPSase_L_D2 PF02786.17 KPI41955.1 - 0.17 11.3 0.4 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GGACT PF06094.12 KPI41957.1 - 6.2e-18 65.5 0.1 1.1e-17 64.8 0.1 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2095 PF09868.9 KPI41957.1 - 0.019 14.9 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) SQHop_cyclase_C PF13243.6 KPI41957.1 - 0.019 14.1 0.1 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain TauD PF02668.16 KPI41958.1 - 2.1e-51 175.3 0.6 2.5e-51 175.1 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KPI41960.1 - 1.3e-33 116.4 41.2 1.5e-33 116.2 40.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI41960.1 - 3e-12 46.1 8.5 3e-12 46.1 8.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KPI41960.1 - 0.046 13.0 16.3 0.019 14.3 6.7 2.4 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KPI41960.1 - 0.5 8.6 6.3 2.4 6.3 5.3 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pro_CA PF00484.19 KPI41961.1 - 0.39 11.0 2.0 63 3.8 0.4 3.1 2 1 0 3 3 3 0 Carbonic anhydrase Clr5 PF14420.6 KPI41962.1 - 1e-14 54.4 0.4 1.7e-14 53.8 0.4 1.3 1 0 0 1 1 1 1 Clr5 domain Mucin PF01456.17 KPI41962.1 - 3.8 7.5 29.3 8.8 6.3 29.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Aldedh PF00171.22 KPI41963.1 - 2.6e-143 477.9 0.0 3e-143 477.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amdase PF17645.1 KPI41964.1 - 3.8e-22 79.0 0.0 4.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Aldo_ket_red PF00248.21 KPI41965.1 - 9.3e-60 202.3 0.2 1.2e-59 202.0 0.2 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FliD_N PF02465.18 KPI41966.1 - 3.9 8.2 9.6 1.9 9.2 3.3 3.0 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus EHN PF06441.12 KPI41967.1 - 1.2e-35 122.2 0.4 1.3e-34 118.8 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI41967.1 - 6.4e-10 39.1 0.0 9.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PelD_GGDEF PF16963.5 KPI41968.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 PelD GGDEF domain Clc-like PF07062.12 KPI41968.1 - 0.013 14.9 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Clc-like BTB PF00651.31 KPI41969.1 - 1e-07 32.1 0.0 1.1e-06 28.9 0.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain GST_N_3 PF13417.6 KPI41970.1 - 3.3e-13 49.8 0.0 7.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI41970.1 - 2.8e-09 37.1 0.0 6.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI41970.1 - 3.4e-07 30.5 0.0 6.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GMC_oxred_N PF00732.19 KPI41972.1 - 9.5e-62 209.0 0.0 1.3e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI41972.1 - 7.3e-30 104.4 0.0 1.3e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI41972.1 - 2.1e-06 27.1 0.3 3.1e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KPI41972.1 - 4.5e-05 22.7 1.7 0.041 13.0 1.9 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KPI41972.1 - 0.00042 19.6 0.1 0.00098 18.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KPI41972.1 - 0.015 14.5 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI41972.1 - 0.017 14.5 1.6 0.86 8.9 2.6 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KPI41972.1 - 0.02 14.5 0.0 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KPI41972.1 - 0.045 12.8 0.1 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KPI41972.1 - 0.14 10.8 0.4 0.24 10.0 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF1385 PF07136.11 KPI41972.1 - 0.25 10.6 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Abhydrolase_6 PF12697.7 KPI41972.1 - 1.2 9.7 5.1 17 5.9 1.6 3.0 1 1 1 3 3 3 0 Alpha/beta hydrolase family Aldedh PF00171.22 KPI41973.1 - 6e-141 470.1 0.0 7.4e-141 469.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KPI41973.1 - 0.023 13.8 0.1 0.049 12.7 0.1 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KPI41973.1 - 0.13 11.7 0.1 0.86 9.0 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Mad3_BUB1_I PF08311.12 KPI41973.1 - 0.23 11.4 0.2 0.5 10.4 0.2 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 CENP-H PF05837.12 KPI41974.1 - 0.00029 21.2 2.3 0.00035 21.0 2.3 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) bZIP_1 PF00170.21 KPI41974.1 - 0.0004 20.4 1.5 0.0004 20.4 1.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor EzrA PF06160.12 KPI41974.1 - 0.00043 18.6 0.2 0.0005 18.4 0.2 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Nnf1 PF03980.14 KPI41974.1 - 0.00081 19.7 1.2 0.00081 19.7 1.2 1.7 2 0 0 2 2 2 1 Nnf1 Tup_N PF08581.10 KPI41974.1 - 0.0013 19.0 0.4 0.011 16.0 0.1 2.1 2 0 0 2 2 2 1 Tup N-terminal ATG16 PF08614.11 KPI41974.1 - 0.0013 19.0 1.8 0.0014 18.8 1.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF745 PF05335.13 KPI41974.1 - 0.0017 18.1 1.0 0.0023 17.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Filament PF00038.21 KPI41974.1 - 0.0022 17.7 1.1 0.0026 17.4 1.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein ABC_tran_CTD PF16326.5 KPI41974.1 - 0.0035 17.6 4.2 0.024 14.9 4.2 1.9 1 1 0 1 1 1 1 ABC transporter C-terminal domain YscO PF07321.12 KPI41974.1 - 0.0047 16.9 1.9 0.0056 16.6 1.9 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO JIP_LZII PF16471.5 KPI41974.1 - 0.0067 16.6 1.0 0.013 15.7 1.1 1.4 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 KPI41974.1 - 0.0068 16.5 3.3 0.018 15.1 3.3 1.7 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein KxDL PF10241.9 KPI41974.1 - 0.0092 16.2 0.4 0.013 15.8 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein APG6_N PF17675.1 KPI41974.1 - 0.011 16.3 2.0 0.014 15.9 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 KPI41974.1 - 0.011 15.6 2.9 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Snapin_Pallidin PF14712.6 KPI41974.1 - 0.012 16.0 0.3 0.018 15.4 0.3 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Spc7 PF08317.11 KPI41974.1 - 0.013 14.4 2.1 0.02 13.8 2.1 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DMPK_coil PF08826.10 KPI41974.1 - 0.014 15.5 2.6 0.049 13.7 0.4 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like BicD PF09730.9 KPI41974.1 - 0.015 13.7 1.2 0.018 13.5 1.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Glyco_H_20C_C PF18088.1 KPI41974.1 - 0.016 15.0 0.8 0.02 14.7 0.8 1.1 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain HAP1_N PF04849.13 KPI41974.1 - 0.016 14.4 2.7 0.29 10.3 0.5 1.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 KPI41974.1 - 0.018 15.4 0.5 0.17 12.3 0.2 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 KPI41974.1 - 0.021 15.1 1.7 0.064 13.6 1.7 1.8 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IFT57 PF10498.9 KPI41974.1 - 0.023 13.7 0.5 0.026 13.5 0.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PilJ PF13675.6 KPI41974.1 - 0.029 14.4 0.4 0.037 14.1 0.4 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_2 PF07716.15 KPI41974.1 - 0.03 14.4 5.4 0.16 12.1 2.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Yuri_gagarin PF15934.5 KPI41974.1 - 0.034 14.0 0.9 0.039 13.8 0.9 1.1 1 0 0 1 1 1 0 Yuri gagarin XhlA PF10779.9 KPI41974.1 - 0.047 13.9 0.8 0.15 12.3 0.2 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Gon7 PF08738.10 KPI41974.1 - 0.047 13.8 0.2 0.071 13.2 0.2 1.3 1 0 0 1 1 1 0 Gon7 family DivIC PF04977.15 KPI41974.1 - 0.048 13.4 3.2 0.059 13.1 2.1 1.7 1 1 1 2 2 2 0 Septum formation initiator Mod_r PF07200.13 KPI41974.1 - 0.052 13.7 0.9 0.069 13.3 0.9 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Occludin_ELL PF07303.13 KPI41974.1 - 0.063 14.0 1.3 0.13 13.0 1.3 1.6 1 1 0 1 1 1 0 Occludin homology domain Fib_alpha PF08702.10 KPI41974.1 - 0.081 13.1 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 KPI41974.1 - 0.082 13.4 2.2 0.13 12.7 2.2 1.4 1 1 0 1 1 1 0 Spectrin repeat Jnk-SapK_ap_N PF09744.9 KPI41974.1 - 0.093 13.0 2.9 0.18 12.0 1.1 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SOAR PF16533.5 KPI41974.1 - 0.095 12.7 1.6 1.9 8.5 1.6 2.1 1 1 0 1 1 1 0 STIM1 Orai1-activating region DUF1664 PF07889.12 KPI41974.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SLATT_5 PF18160.1 KPI41974.1 - 0.16 11.3 0.3 0.23 10.7 0.3 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 TMF_DNA_bd PF12329.8 KPI41974.1 - 0.17 11.9 5.4 1.5 8.8 5.4 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.19 KPI41974.1 - 0.18 11.5 3.9 0.12 12.0 1.8 1.6 1 1 1 2 2 2 0 GrpE TraC PF07820.12 KPI41974.1 - 0.24 11.8 2.6 0.28 11.5 0.1 2.3 1 1 1 3 3 3 0 TraC-like protein YabA PF06156.13 KPI41974.1 - 0.25 12.0 1.7 0.5 11.0 1.8 1.4 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KPI41974.1 - 0.34 11.4 5.5 1.7 9.1 5.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DHR10 PF18595.1 KPI41974.1 - 0.42 10.7 5.7 0.74 9.9 2.4 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DivIVA PF05103.13 KPI41975.1 - 0.087 12.9 4.3 0.082 13.0 1.0 2.4 2 0 0 2 2 2 0 DivIVA protein Fungal_trans PF04082.18 KPI41976.1 - 4.6e-17 61.9 0.3 8.9e-17 61.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.8 KPI41976.1 - 4.2e-11 42.9 2.4 1.1e-10 41.5 1.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) Neuropep_like PF15161.6 KPI41976.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide-like COesterase PF00135.28 KPI41977.1 - 2.4e-94 317.1 0.0 3e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI41977.1 - 2.1e-07 31.0 0.3 1e-06 28.7 0.2 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KPI41978.1 - 2.1e-37 128.9 19.7 2.9e-37 128.4 19.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KPI41978.1 - 2.2 7.9 6.8 12 5.5 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Zn_clus PF00172.18 KPI41979.1 - 6.2e-08 32.6 8.3 1.3e-07 31.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Unstab_antitox PF09720.10 KPI41979.1 - 0.065 13.3 0.4 0.15 12.2 0.4 1.5 1 0 0 1 1 1 0 Putative addiction module component DUF4149 PF13664.6 KPI41979.1 - 0.2 12.0 0.9 0.46 10.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4267 PF14087.6 KPI41980.1 - 5.8e-06 26.3 0.6 7.4e-06 26.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Nop PF01798.18 KPI41981.1 - 2.3e-66 223.6 0.0 3.1e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KPI41981.1 - 3e-46 157.3 2.4 3e-46 157.3 2.4 2.1 2 0 0 2 2 2 1 Prp31 C terminal domain MFS_1 PF07690.16 KPI41982.1 - 4.5e-22 78.5 30.5 1.9e-21 76.4 29.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_glycop_gL PF11108.8 KPI41982.1 - 0.011 15.7 0.1 0.037 14.1 0.0 1.9 2 0 0 2 2 2 0 Viral glycoprotein L Aldo_ket_red PF00248.21 KPI41983.1 - 1.1e-48 166.0 0.0 5.3e-47 160.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.18 KPI41983.1 - 0.0098 14.7 0.0 0.025 13.4 0.0 1.5 1 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Sacchrp_dh_NADP PF03435.18 KPI41983.1 - 0.028 14.7 0.0 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Scytalone_dh PF02982.14 KPI41985.1 - 3e-39 134.4 0.2 3.5e-39 134.2 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KPI41985.1 - 1.2e-07 31.9 0.5 1.5e-07 31.6 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Nefa_Nip30_N PF10187.9 KPI41986.1 - 2.3e-29 101.8 10.4 2.3e-29 101.8 10.4 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Coiled-coil_56 PF09813.9 KPI41986.1 - 0.53 10.4 5.8 0.14 12.2 1.8 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Golgin_A5 PF09787.9 KPI41986.1 - 1.4 8.3 9.9 1.9 7.8 9.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Mito_carr PF00153.27 KPI41987.1 - 4.4e-26 90.6 0.8 3e-15 55.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Cation_ATPase PF13246.6 KPI41987.1 - 0.0051 16.9 0.2 0.17 12.0 0.0 2.9 1 1 2 3 3 3 1 Cation transport ATPase (P-type) DUF3910 PF13049.6 KPI41988.1 - 0.029 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) Peptidase_C50 PF03568.17 KPI41988.1 - 1.2 8.1 4.1 0.75 8.8 0.1 2.3 3 0 0 3 3 3 0 Peptidase family C50 DAO PF01266.24 KPI41989.1 - 8.7e-37 127.5 0.5 9.9e-37 127.3 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI41989.1 - 1.4e-07 30.9 0.1 2.2e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI41989.1 - 2.2e-06 27.8 0.3 6.2e-06 26.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI41989.1 - 0.00016 20.8 0.2 0.44 9.5 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI41989.1 - 0.00021 20.6 1.5 0.0017 17.6 1.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPI41989.1 - 0.00056 19.6 0.6 0.0012 18.5 0.6 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KPI41989.1 - 0.00072 18.7 0.1 0.079 12.0 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPI41989.1 - 0.00079 18.8 0.6 0.0037 16.6 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KPI41989.1 - 0.0024 18.3 0.0 0.0063 16.9 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KPI41989.1 - 0.0029 18.1 0.5 0.0087 16.6 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI41989.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KPI41989.1 - 0.0096 15.8 0.1 0.025 14.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KPI41989.1 - 0.011 15.2 0.1 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Pyr_redox_3 PF13738.6 KPI41989.1 - 0.02 14.2 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KPI41989.1 - 0.029 13.9 0.2 0.069 12.7 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KPI41989.1 - 0.033 12.9 0.2 0.059 12.1 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.15 KPI41989.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-SNAP50_C PF12251.8 KPI41990.1 - 0.027 14.2 0.4 0.052 13.2 0.4 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal AFG1_ATPase PF03969.16 KPI41991.1 - 1.4e-47 162.4 0.3 1.4e-22 80.1 0.0 5.0 5 0 0 5 5 5 3 AFG1-like ATPase AAA_16 PF13191.6 KPI41991.1 - 8.9e-05 22.9 0.0 0.00073 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KPI41991.1 - 0.0089 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI41991.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KPI41991.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KPI41991.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ZapB PF06005.12 KPI41992.1 - 8.1e-05 23.0 5.3 0.0011 19.3 5.3 2.1 1 1 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 KPI41992.1 - 0.00033 20.4 3.4 0.0013 18.5 1.4 2.3 2 1 0 2 2 2 1 Septum formation initiator ADIP PF11559.8 KPI41992.1 - 0.00081 19.5 0.7 0.00093 19.3 0.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 KPI41992.1 - 0.0014 19.0 3.0 0.002 18.5 3.0 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DMPK_coil PF08826.10 KPI41992.1 - 0.0015 18.6 3.3 1.9 8.7 0.0 3.0 1 1 2 3 3 3 2 DMPK coiled coil domain like Rootletin PF15035.6 KPI41992.1 - 0.0019 18.2 2.7 0.0027 17.7 2.7 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 KPI41992.1 - 0.002 18.0 3.7 0.0058 16.5 3.6 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 KPI41992.1 - 0.0025 17.6 3.7 0.0035 17.1 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Ax_dynein_light PF10211.9 KPI41992.1 - 0.0028 17.7 3.2 0.0059 16.6 2.9 1.6 1 1 1 2 2 2 1 Axonemal dynein light chain HALZ PF02183.18 KPI41992.1 - 0.0028 17.8 2.1 0.1 12.9 0.8 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 KPI41992.1 - 0.0033 17.5 5.3 0.29 11.3 3.5 2.7 2 1 1 3 3 3 1 bZIP transcription factor APG17 PF04108.12 KPI41992.1 - 0.0045 16.2 1.0 0.0053 15.9 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 HMMR_N PF15905.5 KPI41992.1 - 0.0053 16.3 2.3 0.0072 15.8 2.3 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Helo_like_N PF17111.5 KPI41992.1 - 0.0084 15.5 2.9 0.023 14.0 1.3 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins FlaC_arch PF05377.11 KPI41992.1 - 0.0086 16.4 2.7 2.9 8.3 0.6 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SHE3 PF17078.5 KPI41992.1 - 0.0092 15.7 3.5 0.2 11.4 4.2 1.8 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 YabA PF06156.13 KPI41992.1 - 0.0095 16.6 2.5 0.031 14.9 2.5 1.8 1 1 0 1 1 1 1 Initiation control protein YabA RNase_E_G PF10150.9 KPI41992.1 - 0.0098 15.3 1.2 0.011 15.2 1.2 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family Spc7 PF08317.11 KPI41992.1 - 0.012 14.6 3.2 0.025 13.5 3.2 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein NRBF2 PF08961.10 KPI41992.1 - 0.014 15.0 1.3 0.018 14.7 1.3 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TPR_MLP1_2 PF07926.12 KPI41992.1 - 0.015 15.3 3.8 0.041 14.0 3.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KPI41992.1 - 0.016 14.6 3.4 0.036 13.4 3.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_3 PF13758.6 KPI41992.1 - 0.017 15.2 0.7 0.038 14.1 0.7 1.6 1 1 0 1 1 1 0 Prefoldin subunit DUF5082 PF16888.5 KPI41992.1 - 0.018 15.3 0.6 0.025 14.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF1351 PF07083.11 KPI41992.1 - 0.018 14.8 0.6 0.022 14.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) WXG100 PF06013.12 KPI41992.1 - 0.018 15.2 0.8 6 7.2 0.0 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.9 KPI41992.1 - 0.02 14.9 3.5 0.027 14.5 3.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC_C PF05010.14 KPI41992.1 - 0.021 14.6 2.3 0.032 14.0 2.3 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cnn_1N PF07989.11 KPI41992.1 - 0.022 14.9 5.2 0.91 9.7 0.6 2.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 KPI41992.1 - 0.022 15.3 1.6 0.03 14.8 1.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 KPI41992.1 - 0.022 15.0 0.9 0.052 13.8 0.9 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KPI41992.1 - 0.023 14.7 0.7 0.046 13.7 0.6 1.5 1 1 1 2 2 2 0 Laminin Domain II TSC22 PF01166.18 KPI41992.1 - 0.025 14.9 4.4 0.046 14.0 2.0 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family Spectrin PF00435.21 KPI41992.1 - 0.026 15.0 1.9 0.056 13.9 1.7 1.6 1 1 1 2 2 2 0 Spectrin repeat DUF4618 PF15397.6 KPI41992.1 - 0.026 14.0 2.1 0.13 11.7 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 KPI41992.1 - 0.026 15.0 1.0 0.085 13.3 1.0 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UPF0449 PF15136.6 KPI41992.1 - 0.028 14.9 2.9 0.23 11.9 1.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 bZIP_2 PF07716.15 KPI41992.1 - 0.029 14.4 5.7 0.15 12.2 0.8 2.9 2 1 1 3 3 3 0 Basic region leucine zipper CmlA_N PF18456.1 KPI41992.1 - 0.03 13.6 0.2 0.039 13.2 0.2 1.2 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain RPW8 PF05659.11 KPI41992.1 - 0.031 14.0 1.1 0.063 13.0 0.7 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3450 PF11932.8 KPI41992.1 - 0.033 13.5 0.8 0.044 13.1 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 KPI41992.1 - 0.039 11.9 0.4 0.042 11.8 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KPI41992.1 - 0.043 13.2 1.0 0.059 12.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 KPI41992.1 - 0.044 13.7 4.4 0.26 11.3 1.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 KPI41992.1 - 0.045 14.1 1.3 1.4 9.3 0.8 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KPI41992.1 - 0.051 14.2 1.7 0.18 12.5 0.5 2.0 1 1 1 2 2 2 0 SlyX DASH_Duo1 PF08651.10 KPI41992.1 - 0.052 13.3 1.0 0.33 10.7 0.2 2.1 1 1 1 3 3 3 0 DASH complex subunit Duo1 Seryl_tRNA_N PF02403.22 KPI41992.1 - 0.06 13.6 3.8 4 7.7 3.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain USP8_interact PF08941.10 KPI41992.1 - 0.062 13.1 0.3 0.09 12.6 0.2 1.3 1 1 0 1 1 1 0 USP8 interacting DivIVA PF05103.13 KPI41992.1 - 0.069 13.2 1.8 0.13 12.4 1.8 1.5 1 1 0 1 1 1 0 DivIVA protein Spc24 PF08286.11 KPI41992.1 - 0.071 13.4 5.6 0.7 10.2 2.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Occludin_ELL PF07303.13 KPI41992.1 - 0.072 13.8 0.5 0.1 13.3 0.5 1.3 1 0 0 1 1 1 0 Occludin homology domain HIP1_clath_bdg PF16515.5 KPI41992.1 - 0.075 13.6 3.8 1.5 9.4 3.8 2.1 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 KPI41992.1 - 0.079 13.9 5.1 7.7 7.5 0.0 2.5 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4140 PF13600.6 KPI41992.1 - 0.083 13.3 4.3 1.2 9.6 1.9 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mce4_CUP1 PF11887.8 KPI41992.1 - 0.085 12.3 0.4 0.47 9.9 0.0 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative TMF_TATA_bd PF12325.8 KPI41992.1 - 0.089 13.0 5.7 0.2 11.9 5.7 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CK2S PF15011.6 KPI41992.1 - 0.1 12.5 1.8 1.6 8.6 0.6 2.1 1 1 1 2 2 2 0 Casein Kinase 2 substrate Sec20 PF03908.13 KPI41992.1 - 0.11 12.4 0.3 0.17 11.8 0.3 1.4 1 1 0 1 1 1 0 Sec20 M PF02370.16 KPI41992.1 - 0.12 13.0 5.0 53 4.9 1.2 3.6 2 1 2 4 4 4 0 M protein repeat TMF_DNA_bd PF12329.8 KPI41992.1 - 0.16 12.0 6.0 0.38 10.8 5.8 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Syntaxin-6_N PF09177.11 KPI41992.1 - 0.18 12.4 2.9 0.62 10.7 1.0 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal THOC7 PF05615.13 KPI41992.1 - 0.22 11.8 5.3 0.79 10.0 2.2 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 EMP24_GP25L PF01105.24 KPI41992.1 - 0.55 10.1 2.6 1.9 8.4 1.1 1.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Cep57_CLD_2 PF14197.6 KPI41992.1 - 0.69 10.0 5.9 17 5.6 1.9 2.5 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Lactamase_B PF00753.27 KPI41993.1 - 6.4e-09 36.1 0.9 9e-09 35.6 0.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI41993.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Zn_clus PF00172.18 KPI41994.1 - 5e-06 26.5 11.2 8.3e-06 25.8 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI41994.1 - 0.00057 19.0 0.0 0.027 13.5 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Dickkopf_N PF04706.12 KPI41994.1 - 0.94 10.0 6.9 2.1 8.9 6.9 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region CHORD PF04968.12 KPI41995.1 - 0.15 12.8 3.8 0.96 10.2 0.2 2.3 2 0 0 2 2 2 0 CHORD Ank_4 PF13637.6 KPI41996.1 - 7.7e-11 42.3 0.0 0.00025 21.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TPR_2 PF07719.17 KPI41996.1 - 5.9e-08 32.2 4.7 0.0086 16.1 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KPI41996.1 - 7.9e-08 31.9 6.3 0.00039 20.4 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KPI41996.1 - 1.1e-07 31.4 5.9 0.036 13.9 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KPI41996.1 - 1.2e-07 31.9 2.1 0.07 13.4 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Ank_2 PF12796.7 KPI41996.1 - 1.2e-06 29.0 0.0 0.023 15.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) TPR_19 PF14559.6 KPI41996.1 - 2.4e-06 28.0 1.3 0.0017 18.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI41996.1 - 4.6e-05 23.6 5.4 0.0041 17.3 0.9 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Ank_5 PF13857.6 KPI41996.1 - 6.8e-05 23.1 0.1 0.12 12.7 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeats (many copies) TPR_7 PF13176.6 KPI41996.1 - 0.00013 21.7 0.5 0.067 13.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPI41996.1 - 0.00021 21.8 0.2 1.7 9.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KPI41996.1 - 0.00073 20.0 1.5 2.8 8.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KPI41996.1 - 0.0014 18.4 0.7 0.14 12.1 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank PF00023.30 KPI41996.1 - 0.0015 18.9 0.5 0.11 12.9 0.0 3.4 4 0 0 4 4 3 1 Ankyrin repeat Helo_like_N PF17111.5 KPI41996.1 - 0.0037 16.7 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF761 PF05553.11 KPI41996.1 - 0.12 12.0 0.2 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Cotton fibre expressed protein TPR_11 PF13414.6 KPI41996.1 - 2.9 7.7 4.6 18 5.1 0.2 3.5 4 0 0 4 4 4 0 TPR repeat SAP PF02037.27 KPI41997.1 - 0.0013 18.5 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 SAP domain FAD_binding_4 PF01565.23 KPI41998.1 - 2.8e-22 79.0 0.8 4.5e-22 78.3 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.8 KPI41999.1 - 6.9e-10 38.3 0.5 1.1e-09 37.6 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain HEAT_2 PF13646.6 KPI41999.1 - 0.087 13.2 0.0 5.6 7.4 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats P21-Arc PF04062.14 KPI42000.1 - 1.1e-63 214.3 0.0 2.2e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit IF4E PF01652.18 KPI42000.1 - 1.5e-54 184.1 1.2 2.3e-54 183.5 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 KPI42000.1 - 1.5e-31 109.9 0.1 2.6e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Citrate_synt PF00285.21 KPI42001.1 - 1.1e-83 281.4 0.0 3.5e-64 217.1 0.0 2.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Eclosion PF04736.12 KPI42001.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone p450 PF00067.22 KPI42002.1 - 1.3e-65 221.9 0.0 1.6e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 KPI42004.1 - 9.7e-09 35.2 0.2 2.1e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_130 PF04041.13 KPI42004.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase adh_short_C2 PF13561.6 KPI42005.1 - 9.9e-54 182.4 1.3 1.1e-53 182.2 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42005.1 - 3.3e-39 134.4 0.2 4.9e-39 133.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42005.1 - 6e-08 32.8 0.6 8.2e-08 32.4 0.6 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KPI42005.1 - 0.007 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.21 KPI42005.1 - 0.011 15.2 0.1 0.052 13.0 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI42005.1 - 0.02 14.0 0.1 0.065 12.4 0.1 1.8 1 1 1 2 2 2 0 Male sterility protein Radical_SAM PF04055.21 KPI42005.1 - 0.15 12.4 0.0 0.97 9.8 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily ILVD_EDD PF00920.21 KPI42006.1 - 1.1e-149 499.4 0.0 1.4e-149 499.1 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family TENA_THI-4 PF03070.16 KPI42006.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Glyco_hydro_16 PF00722.21 KPI42008.1 - 9.5e-09 35.0 0.0 2.8e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 PIR PF00399.19 KPI42008.1 - 3.8e-06 26.3 2.0 1.5e-05 24.4 2.0 2.1 1 0 0 1 1 1 1 Yeast PIR protein repeat GMC_oxred_N PF00732.19 KPI42009.1 - 3e-57 194.3 0.0 3.7e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI42009.1 - 1.4e-35 122.9 0.0 3.8e-35 121.5 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI42009.1 - 0.0011 18.1 0.2 0.0033 16.5 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KPI42009.1 - 0.023 14.3 1.6 0.056 13.0 1.6 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI42009.1 - 0.029 14.6 1.2 0.093 13.0 0.5 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI42009.1 - 0.047 12.9 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI42009.1 - 0.11 11.6 2.4 3.7 6.5 0.9 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HhH-GPD PF00730.25 KPI42010.1 - 0.064 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF2125 PF09898.9 KPI42010.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Transp_cyt_pur PF02133.15 KPI42011.1 - 7.6e-68 229.3 39.5 9.4e-68 229.0 39.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Baculo_PEP_C PF04513.12 KPI42012.1 - 0.0065 16.5 0.3 0.011 15.7 0.3 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus GARP PF16731.5 KPI42012.1 - 0.61 9.8 12.9 1.2 8.7 12.6 1.5 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Miga PF10265.9 KPI42012.1 - 2.3 7.1 5.4 2.6 6.9 5.4 1.1 1 0 0 1 1 1 0 Mitoguardin Stevor PF17410.2 KPI42012.1 - 3.6 7.1 4.5 4.2 6.8 4.5 1.0 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Mago_nashi PF02792.14 KPI42013.1 - 1.1e-72 242.8 0.3 1.2e-72 242.6 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein GFA PF04828.14 KPI42014.1 - 2e-17 63.3 0.1 2e-17 63.3 0.1 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF4300 PF14133.6 KPI42015.1 - 0.086 12.5 0.2 0.34 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) Dynamin_M PF01031.20 KPI42016.1 - 4.3e-103 344.4 0.0 7.6e-103 343.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KPI42016.1 - 8.3e-57 191.9 0.0 1.9e-56 190.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KPI42016.1 - 8.1e-30 102.8 7.1 8.1e-30 102.8 7.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KPI42016.1 - 3.2e-05 24.0 0.3 0.00018 21.6 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KPI42016.1 - 0.13 11.9 3.0 7 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain CoA_trans PF01144.23 KPI42017.1 - 5.8e-100 333.1 3.7 1.2e-61 207.9 0.3 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KPI42017.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain ORC5_C PF14630.6 KPI42019.1 - 1.1e-38 133.5 0.1 1.6e-38 132.9 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KPI42019.1 - 0.00049 20.5 2.7 0.00056 20.3 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF1776 PF08643.10 KPI42019.1 - 0.099 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_N PF08240.12 KPI42021.1 - 1.3e-20 73.3 0.1 3e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI42021.1 - 2.8e-15 56.5 6.0 8.2e-15 54.9 3.3 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI42021.1 - 2.1e-06 27.4 3.1 3.6e-06 26.6 3.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short PF00106.25 KPI42021.1 - 0.2 11.1 3.8 0.44 10.0 2.8 2.0 2 1 0 2 2 2 0 short chain dehydrogenase ECH_1 PF00378.20 KPI42022.1 - 6.4e-47 160.0 0.0 2.5e-35 122.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI42022.1 - 2.5e-24 86.4 0.3 1.2e-20 74.3 0.0 2.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KPI42022.1 - 0.004 17.1 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 DUF3005 PF11448.8 KPI42022.1 - 0.29 11.2 0.8 5.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) Fe-ADH PF00465.19 KPI42023.1 - 2.6e-61 207.5 0.0 3.2e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KPI42023.1 - 1.1e-09 38.4 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldo_ket_red PF00248.21 KPI42024.1 - 1.2e-51 175.7 0.0 6.5e-33 114.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Sugar_tr PF00083.24 KPI42025.1 - 3.3e-75 253.7 18.1 1.2e-69 235.4 9.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42025.1 - 1.3e-22 80.2 51.1 7.5e-18 64.6 20.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Pex14_N PF04695.13 KPI42025.1 - 0.21 12.2 0.9 65 4.1 0.0 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YfiO PF13525.6 KPI42026.1 - 0.059 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein CHORD PF04968.12 KPI42026.1 - 0.11 13.2 0.4 0.11 13.2 0.4 2.6 2 1 0 2 2 2 0 CHORD Glyco_hydro_3 PF00933.21 KPI42028.1 - 1.5e-33 116.6 0.0 1.2e-30 107.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPI42028.1 - 3e-08 33.9 0.0 1.2e-07 31.9 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain TGT PF01702.18 KPI42029.1 - 4.8e-63 213.4 0.0 6.3e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Sugar_tr PF00083.24 KPI42030.1 - 7.2e-63 213.0 35.6 4.9e-37 127.9 12.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42030.1 - 4.7e-26 91.6 23.7 4.7e-26 91.6 23.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI42030.1 - 6.8e-07 28.9 6.7 6.8e-07 28.9 6.7 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_holin_3_2 PF04550.12 KPI42030.1 - 2.3 8.8 6.9 0.5 10.9 0.6 3.1 3 1 0 3 3 3 0 Phage holin family 2 zinc_ribbon_6 PF14599.6 KPI42031.1 - 2.9e-21 75.2 0.8 2.9e-21 75.2 0.8 3.8 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 KPI42031.1 - 1.3e-18 67.3 19.3 1.3e-18 67.3 19.3 3.6 2 1 1 3 3 3 1 CHY zinc finger ADH_N PF08240.12 KPI42031.1 - 1.8e-06 27.8 0.3 1.8e-06 27.8 0.3 4.5 4 1 0 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI42031.1 - 3.2e-06 27.1 0.6 9.5e-06 25.6 0.6 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.6 KPI42031.1 - 1.2e-05 25.5 10.8 1.2e-05 25.5 10.8 5.0 2 1 3 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KPI42031.1 - 0.00018 21.4 8.5 0.00018 21.4 8.5 5.4 3 2 2 5 5 5 1 zinc-RING finger domain Zn-C2H2_12 PF18112.1 KPI42031.1 - 0.0095 16.4 2.5 0.34 11.4 0.2 2.7 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_2 PF13923.6 KPI42031.1 - 0.011 15.5 8.6 0.011 15.5 8.6 4.7 6 0 0 6 6 6 0 Zinc finger, C3HC4 type (RING finger) AAA_33 PF13671.6 KPI42033.1 - 0.077 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_10 PF13673.7 KPI42034.1 - 4.4e-11 42.8 0.0 7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI42034.1 - 1e-09 38.7 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI42034.1 - 4.7e-09 36.5 0.0 8.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPI42034.1 - 3.6e-07 30.1 0.0 6.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KPI42034.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI42034.1 - 0.00072 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KPI42034.1 - 0.0065 16.2 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ AA_permease_2 PF13520.6 KPI42035.1 - 5.5e-82 275.9 34.5 7.3e-82 275.5 34.5 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KPI42036.1 - 5.6e-26 91.2 1.6 1.3e-23 83.4 1.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetate_kinase PF00871.17 KPI42036.1 - 0.17 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Acetokinase family PfkB PF00294.24 KPI42037.1 - 1e-42 146.5 1.6 1.3e-42 146.1 1.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PLU-1 PF08429.11 KPI42039.1 - 1.6e-86 290.6 8.4 3.2e-84 283.0 5.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KPI42039.1 - 5.8e-44 149.2 0.1 1.5e-43 147.9 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KPI42039.1 - 2e-21 76.5 0.4 7.2e-21 74.7 0.1 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KPI42039.1 - 5.5e-16 58.2 5.4 7.6e-16 57.8 0.4 3.3 3 0 0 3 3 3 1 jmjN domain zf-C5HC2 PF02928.16 KPI42039.1 - 1.4e-12 47.8 8.2 3e-12 46.7 8.2 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 KPI42039.1 - 1.1e-06 28.5 8.9 1.1e-06 28.5 8.9 3.5 3 0 0 3 3 3 1 PHD-finger DUF349 PF03993.12 KPI42039.1 - 1.1 9.5 4.7 5.7 7.3 0.0 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) F_bP_aldolase PF01116.20 KPI42040.1 - 2.5e-81 273.2 0.0 2.8e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_1 PF01979.20 KPI42040.1 - 0.12 11.7 1.0 0.28 10.5 0.9 1.5 1 1 0 1 1 1 0 Amidohydrolase family NAD_binding_4 PF07993.12 KPI42041.1 - 1.3e-32 113.0 0.0 2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DHQ_synthase PF01761.20 KPI42041.1 - 8.7e-31 107.0 0.0 2.3e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 3-dehydroquinate synthase AMP-binding PF00501.28 KPI42041.1 - 9.4e-23 80.5 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KPI42041.1 - 9.4e-08 31.8 0.0 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KPI42041.1 - 3.1e-06 27.5 0.1 9.8e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Fe-ADH_2 PF13685.6 KPI42041.1 - 0.00064 19.5 0.0 0.05 13.3 0.0 3.1 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase KR PF08659.10 KPI42041.1 - 0.00094 19.1 0.4 0.013 15.4 0.4 2.4 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI42041.1 - 0.045 13.1 0.7 0.44 9.9 0.1 2.7 3 1 0 3 3 3 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KPI42041.1 - 0.052 14.0 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GH3 PF03321.13 KPI42041.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter TRI12 PF06609.13 KPI42044.1 - 1.7e-73 248.0 19.7 2.3e-73 247.6 19.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI42044.1 - 1.5e-19 70.2 54.5 1.8e-19 69.9 36.5 3.5 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI42044.1 - 4.7e-11 42.2 8.0 4.7e-11 42.2 8.0 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter DUF4668 PF15701.5 KPI42044.1 - 0.017 14.9 0.5 0.062 13.1 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Pox_A14 PF05767.12 KPI42044.1 - 0.041 14.0 0.3 0.041 14.0 0.3 3.2 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 DUF443 PF04276.12 KPI42044.1 - 7.9 6.2 9.5 0.52 10.1 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) MFS_1 PF07690.16 KPI42047.1 - 4.7e-32 111.3 29.8 4.7e-32 111.3 29.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.24 KPI42048.1 - 2.8e-29 102.3 2.4 4.6e-29 101.6 2.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAN_1 PF00024.26 KPI42048.1 - 4.6e-09 36.1 10.7 0.0049 16.8 0.2 3.4 3 0 0 3 3 3 3 PAN domain Acyl-CoA_dh_2 PF08028.11 KPI42048.1 - 6.5e-06 26.5 1.3 1.3e-05 25.4 1.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CD34_antigen PF06365.12 KPI42048.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.10 KPI42048.1 - 0.017 14.5 0.4 0.032 13.6 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PAN_4 PF14295.6 KPI42048.1 - 0.03 14.2 22.1 1.6 8.7 1.0 4.1 3 2 0 3 3 3 0 PAN domain Acyl-CoA_dh_M PF02770.19 KPI42048.1 - 0.042 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain EphA2_TM PF14575.6 KPI42048.1 - 0.14 13.0 0.0 0.44 11.5 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PAN_3 PF08277.12 KPI42048.1 - 1.6 8.6 6.5 12 5.8 0.3 2.9 3 0 0 3 3 3 0 PAN-like domain FAT PF02259.23 KPI42049.1 - 5.8e-73 246.1 6.8 1.4e-72 244.8 6.8 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KPI42049.1 - 1.4e-32 113.5 0.1 4e-32 112.0 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GreA_GreB_N PF03449.15 KPI42050.1 - 0.0019 18.3 0.8 0.0037 17.4 0.8 1.4 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal ZoocinA_TRD PF16775.5 KPI42050.1 - 0.017 15.2 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme p450 PF00067.22 KPI42051.1 - 3.7e-39 134.8 0.2 4.7e-39 134.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 HIRAN PF08797.11 KPI42051.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain Fungal_trans PF04082.18 KPI42053.1 - 1.2e-21 77.0 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI42053.1 - 1.1e-07 31.8 8.9 2e-07 31.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_1 PF00734.18 KPI42054.1 - 1.8e-11 43.8 9.7 8.4e-11 41.6 9.7 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain DPBB_1 PF03330.18 KPI42054.1 - 0.00025 21.3 0.1 0.00078 19.7 0.1 2.0 1 1 0 1 1 1 1 Lytic transglycolase ECH_1 PF00378.20 KPI42056.1 - 6.3e-48 163.3 0.0 1.3e-47 162.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI42056.1 - 6e-29 101.6 0.4 9.8e-27 94.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SnoaL PF07366.12 KPI42056.1 - 0.12 12.2 0.2 0.36 10.6 0.2 1.8 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase TAFII28 PF04719.14 KPI42058.1 - 3.7e-18 65.4 0.3 1.8e-17 63.2 0.3 2.0 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Sigma70_ner PF04546.13 KPI42058.1 - 0.1 12.5 7.8 0.25 11.2 7.8 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region Cytochrom_B561 PF03188.16 KPI42059.1 - 2e-06 28.0 5.2 3.1e-06 27.4 5.2 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Amidase PF01425.21 KPI42060.1 - 3.3e-89 299.9 0.0 1.7e-88 297.6 0.0 1.8 1 1 0 1 1 1 1 Amidase DUF2608 PF11019.8 KPI42060.1 - 0.16 11.4 0.1 25 4.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2608) PgdA_N PF18627.1 KPI42060.1 - 0.19 11.4 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain SGL PF08450.12 KPI42061.1 - 2.6e-12 46.8 0.0 5e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KPI42061.1 - 0.00013 22.0 0.0 0.00048 20.2 0.0 2.0 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KPI42061.1 - 0.011 15.9 0.0 0.047 13.9 0.0 2.3 1 0 0 1 1 1 0 Arylesterase DUF2012 PF09430.10 KPI42062.1 - 1.2e-09 38.3 0.0 1.1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) DUF4158 PF13700.6 KPI42063.1 - 0.012 15.5 0.2 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) YolD PF08863.10 KPI42063.1 - 0.022 14.8 0.6 0.046 13.8 0.6 1.5 1 0 0 1 1 1 0 YolD-like protein Ammonium_transp PF00909.21 KPI42064.1 - 4.5e-116 387.8 30.3 5.1e-116 387.6 30.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4395 PF14340.6 KPI42064.1 - 0.0036 17.6 2.7 0.0036 17.6 2.7 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4395) UPF0029 PF01205.19 KPI42065.1 - 9.1e-23 80.6 0.2 7.1e-22 77.7 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 Kelch_5 PF13854.6 KPI42067.1 - 8.6e-13 48.0 2.5 4.9e-08 32.8 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KPI42067.1 - 2.5e-08 34.0 4.8 0.049 13.9 0.1 5.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KPI42067.1 - 1.3e-06 28.3 6.9 0.45 10.6 0.1 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KPI42067.1 - 1.4e-06 28.3 1.2 0.37 11.2 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KPI42067.1 - 2.5e-05 24.1 4.6 1.3 9.1 0.0 4.6 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KPI42067.1 - 5.4e-05 22.7 2.8 0.48 10.0 0.0 4.6 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.10 KPI42067.1 - 0.012 15.0 0.7 0.029 13.8 0.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KPI42067.1 - 0.017 14.8 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Myc_target_1 PF15179.6 KPI42067.1 - 0.84 9.5 4.9 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Myc target protein 1 GTP_EFTU PF00009.27 KPI42068.1 - 2e-32 112.3 0.7 9e-32 110.2 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KPI42068.1 - 4.8e-17 62.0 0.1 1.3e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KPI42068.1 - 1.6e-13 50.8 1.7 3.6e-10 40.1 0.1 3.4 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KPI42068.1 - 2.5e-10 40.1 0.1 8.9e-10 38.3 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KPI42068.1 - 1.5e-07 31.5 0.3 1.4e-06 28.3 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 KPI42068.1 - 0.00012 22.3 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KPI42068.1 - 0.01 15.6 0.0 0.036 13.8 0.0 2.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KPI42068.1 - 0.047 13.3 0.0 0.3 10.7 0.0 2.5 1 1 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 KPI42068.1 - 0.86 9.5 6.9 0.17 11.8 0.3 3.1 3 1 0 3 3 3 0 RsgA GTPase Peptidase_M20 PF01546.28 KPI42069.1 - 3.8e-19 69.2 0.4 6.2e-19 68.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI42069.1 - 2.8e-14 53.0 0.0 5.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain AWS PF17907.1 KPI42069.1 - 0.2 11.7 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 AWS domain MIP PF00230.20 KPI42070.1 - 7.1e-42 143.7 4.4 9.4e-42 143.2 4.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 KPI42071.1 - 1.4e-61 208.7 19.9 5.2e-60 203.6 19.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42071.1 - 1.1e-18 67.3 18.6 1.1e-18 67.3 18.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI42072.1 - 7.5e-43 146.8 26.3 9.2e-43 146.5 26.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI42072.1 - 5.2e-20 71.7 54.6 5.2e-20 71.7 54.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI42072.1 - 1.2e-13 50.8 4.8 1.2e-13 50.8 4.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 KPI42072.1 - 0.0017 16.7 2.0 0.0048 15.2 2.0 1.7 1 0 0 1 1 1 1 BT1 family Carn_acyltransf PF00755.20 KPI42073.1 - 8.3e-209 695.0 0.0 1.9e-208 693.8 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase UPF0020 PF01170.18 KPI42075.1 - 1.5e-09 37.8 0.7 1.8e-07 31.1 0.7 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KPI42075.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 DNA methylase Tubulin_C PF03953.17 KPI42076.1 - 2.5e-50 169.9 0.1 4.1e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KPI42076.1 - 1.5e-49 168.9 0.0 2.5e-30 106.1 0.0 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KPI42076.1 - 0.0026 17.5 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain DNA_RNApol_7kD PF03604.13 KPI42077.1 - 0.0061 16.2 1.3 0.0077 15.9 0.1 1.7 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 KPI42077.1 - 0.037 13.8 0.1 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein YjzC PF14168.6 KPI42077.1 - 0.086 13.2 0.0 4.3 7.8 0.0 2.3 2 0 0 2 2 2 0 YjzC-like protein MIP PF00230.20 KPI42080.1 - 3.8e-49 167.4 10.7 5e-49 167.1 10.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Mur_ligase PF01225.25 KPI42081.1 - 0.17 12.3 0.1 0.36 11.2 0.1 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain MAP65_ASE1 PF03999.12 KPI42082.1 - 0.76 8.4 7.1 0.84 8.3 7.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) adh_short_C2 PF13561.6 KPI42083.1 - 1.6e-29 103.2 0.1 2.1e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42083.1 - 6.7e-24 84.4 0.2 8.2e-24 84.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KPI42083.1 - 0.00036 19.9 0.2 0.00065 19.0 0.2 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KPI42083.1 - 0.002 18.6 0.6 0.0029 18.0 0.1 1.5 2 0 0 2 2 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KPI42083.1 - 0.0027 18.0 0.3 0.012 15.9 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KPI42083.1 - 0.0065 16.4 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 KPI42083.1 - 0.0083 16.4 0.2 0.16 12.2 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.6 KPI42083.1 - 0.026 13.8 0.4 0.036 13.3 0.4 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KPI42083.1 - 0.028 14.1 0.2 0.052 13.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KPI42083.1 - 0.068 13.1 0.4 0.18 11.7 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KPI42083.1 - 0.071 13.7 1.2 0.15 12.6 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 KPI42083.1 - 0.075 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 KPI42083.1 - 0.077 12.2 0.5 0.11 11.7 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KPI42083.1 - 0.085 12.1 1.8 0.13 11.5 1.9 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.8 KPI42083.1 - 0.12 12.2 0.3 0.23 11.2 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_oxidored PF12831.7 KPI42083.1 - 0.32 10.3 1.2 0.59 9.4 1.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KPI42084.1 - 3.1e-20 72.4 21.9 6.7e-20 71.3 11.7 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily PTR2 PF00854.21 KPI42084.1 - 0.45 9.3 7.1 0.26 10.1 2.9 2.3 2 0 0 2 2 2 0 POT family Sulf_transp PF04143.14 KPI42085.1 - 3.2e-32 112.3 34.3 5.5e-32 111.6 34.3 1.3 1 1 0 1 1 1 1 Sulphur transport p450 PF00067.22 KPI42086.1 - 2.2e-73 247.6 0.0 2.6e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YolD PF08863.10 KPI42086.1 - 0.043 13.9 0.4 0.082 13.0 0.4 1.4 1 0 0 1 1 1 0 YolD-like protein HATPase_c PF02518.26 KPI42087.1 - 6.9e-31 107.1 0.0 2e-30 105.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI42087.1 - 6.9e-20 71.3 0.1 1.5e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KPI42087.1 - 1.6e-18 66.5 0.0 7e-18 64.4 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KPI42087.1 - 2.5e-14 54.0 0.0 8.6e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.6 KPI42087.1 - 1.9e-13 50.9 0.1 5.2e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KPI42087.1 - 4.1e-07 30.7 0.1 9.4e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KPI42087.1 - 9.2e-05 22.8 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 KPI42087.1 - 0.00021 21.1 1.7 0.0005 19.9 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.6 KPI42087.1 - 0.00078 19.7 0.2 0.00078 19.7 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Pkinase PF00069.25 KPI42087.1 - 0.0041 16.5 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Glycos_transf_3 PF00591.21 KPI42088.1 - 2.8e-61 207.3 0.0 3.9e-48 164.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KPI42088.1 - 1.5e-06 27.9 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Acetate_kinase PF00871.17 KPI42089.1 - 3.6e-95 318.9 0.0 4.3e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family NUDIX PF00293.28 KPI42090.1 - 2.1e-17 63.4 0.2 4.6e-17 62.3 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KPI42090.1 - 2.5e-07 31.3 0.0 8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KPI42090.1 - 1.2e-06 28.1 0.7 2.1e-06 27.3 0.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.24 KPI42091.1 - 1.1e-49 169.6 18.4 6.3e-36 124.2 7.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42091.1 - 1.7e-18 66.6 40.3 5.3e-16 58.5 21.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5362 PF17319.2 KPI42091.1 - 6.1 6.8 9.2 7.5 6.5 0.3 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5362) Abhydrolase_1 PF00561.20 KPI42092.1 - 2.5e-10 40.4 0.5 1e-09 38.5 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42092.1 - 9.3e-08 32.9 0.3 1.2e-07 32.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family GHMP_kinases_C PF08544.13 KPI42092.1 - 0.03 14.7 1.1 0.092 13.1 0.6 2.1 2 1 1 3 3 3 0 GHMP kinases C terminal tRNA-synt_1c PF00749.21 KPI42093.1 - 1.5e-85 286.9 0.0 2.4e-85 286.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KPI42093.1 - 3e-20 72.8 1.0 5.6e-20 71.9 1.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Peptidase_S15 PF02129.18 KPI42094.1 - 4.1e-26 92.2 0.1 4.7e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KPI42094.1 - 0.072 11.8 0.0 6.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DIOX_N PF14226.6 KPI42096.1 - 2.1e-25 89.8 0.0 3.4e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI42096.1 - 1.7e-17 63.7 0.1 8.8e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOB1_Zn_bind PF08772.11 KPI42097.1 - 1.4e-30 105.2 2.1 2.3e-30 104.5 2.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KPI42097.1 - 7.5e-28 96.9 0.1 3.3e-27 94.8 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KPI42097.1 - 0.02 14.5 2.7 0.052 13.2 0.9 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 KPI42097.1 - 0.028 14.4 0.3 1 9.4 1.0 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WRNPLPNID PF15017.6 KPI42097.1 - 0.032 15.1 4.7 0.032 15.1 4.7 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Rhodanese_C PF12368.8 KPI42097.1 - 0.32 11.4 4.0 0.62 10.5 4.0 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Pox_A28 PF04584.14 KPI42098.1 - 0.21 11.8 0.1 0.29 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A28 family DUF697 PF05128.12 KPI42099.1 - 0.15 11.8 1.2 0.24 11.1 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF697) Ribosomal_L10 PF00466.20 KPI42100.1 - 0.00062 19.9 0.1 0.0059 16.7 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L10 YfhO PF09586.10 KPI42101.1 - 0.0093 14.3 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF2207 PF09972.9 KPI42101.1 - 0.025 13.4 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BatD PF13584.6 KPI42101.1 - 0.027 13.3 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance UcrQ PF02939.16 KPI42101.1 - 0.043 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 UcrQ family LuxS PF02664.15 KPI42101.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) CcmH PF03918.14 KPI42101.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein WD40 PF00400.32 KPI42102.1 - 1.5e-23 82.7 9.5 2e-05 25.3 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI42102.1 - 2.4e-13 50.2 0.1 0.0011 19.2 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI42102.1 - 5.3e-05 22.1 0.2 2 7.0 0.0 3.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KPI42102.1 - 0.00015 22.1 1.7 3.8 8.1 0.0 4.8 5 0 0 5 5 5 2 PQQ-like domain BBS2_Mid PF14783.6 KPI42102.1 - 0.00029 20.8 0.4 6.7 6.8 0.1 4.4 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KPI42102.1 - 0.0017 18.2 0.0 3.7 7.6 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KPI42102.1 - 0.0019 16.8 0.1 0.03 12.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KPI42102.1 - 0.1 11.5 0.0 18 4.1 0.0 3.1 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribonuc_L-PSP PF01042.21 KPI42103.1 - 1.9e-19 69.8 0.0 2.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Asp PF00026.23 KPI42104.1 - 7e-13 48.7 0.2 3.3e-12 46.5 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI42104.1 - 6.5e-06 26.5 0.1 2.7e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI42104.1 - 0.0013 19.3 0.2 1.7 9.4 0.0 2.9 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI42104.1 - 0.0016 19.0 0.0 0.43 11.2 0.0 2.5 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease MFS_1 PF07690.16 KPI42105.1 - 8.8e-27 93.9 27.7 5.3e-26 91.4 27.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KPI42106.1 - 8.2e-09 34.9 0.1 1.7e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI42106.1 - 2.2e-08 34.1 11.0 4.3e-08 33.2 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KPI42107.1 - 2.8e-85 286.5 0.0 3.4e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RICTOR_N PF14664.6 KPI42107.1 - 0.065 12.2 0.1 0.098 11.6 0.1 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Aft1_HRR PF11787.8 KPI42108.1 - 3.4 8.9 9.4 26 6.1 9.4 2.3 1 1 0 1 1 1 0 Aft1 HRR domain MFS_1 PF07690.16 KPI42109.1 - 7.2e-47 160.0 47.6 6.4e-42 143.7 26.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPI42109.1 - 3.1e-10 39.2 25.1 7.1e-06 24.8 6.9 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KPI42109.1 - 1.1e-06 27.9 14.0 6.9e-05 21.9 4.8 3.0 2 1 1 3 3 3 2 MFS_1 like family CLN3 PF02487.17 KPI42109.1 - 0.12 11.5 4.1 0.045 12.8 1.2 1.9 2 0 0 2 2 2 0 CLN3 protein OATP PF03137.20 KPI42109.1 - 0.15 10.3 8.8 0.27 9.5 2.6 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.22 KPI42109.1 - 1.8 7.7 11.7 0.14 11.3 0.9 3.0 2 2 1 3 3 3 0 ZIP Zinc transporter Amidohydro_2 PF04909.14 KPI42110.1 - 6.7e-24 85.2 1.2 8.1e-24 84.9 1.2 1.1 1 0 0 1 1 1 1 Amidohydrolase SAM_decarbox PF01536.16 KPI42112.1 - 5.6e-129 430.2 0.0 6.8e-129 429.9 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PHAT PF09246.10 KPI42112.1 - 0.05 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 PHAT RNase_3_N PF18497.1 KPI42113.1 - 0.11 12.7 0.1 12 6.2 0.1 2.5 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain BUD22 PF09073.10 KPI42113.1 - 0.29 10.4 7.3 0.4 10.0 7.3 1.2 1 0 0 1 1 1 0 BUD22 PhzC-PhzF PF02567.16 KPI42115.1 - 2.1e-31 109.5 0.1 6.5e-18 65.2 0.0 2.0 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein KdpC PF02669.15 KPI42116.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Mito_carr PF00153.27 KPI42117.1 - 7.2e-52 173.3 1.9 4.7e-17 61.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_12 PF13424.6 KPI42118.1 - 2.4e-13 50.2 2.0 5.6e-07 29.8 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPI42118.1 - 4e-05 23.3 0.2 1.4 8.9 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KPI42118.1 - 8.6e-05 23.0 0.2 0.00057 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KPI42118.1 - 0.00023 21.1 0.0 0.00077 19.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 KPI42118.1 - 0.0016 18.4 0.7 26 5.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2075 PF09848.9 KPI42118.1 - 0.0019 17.5 0.1 0.0079 15.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KPI42118.1 - 0.0022 18.3 0.8 0.039 14.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain TPR_7 PF13176.6 KPI42118.1 - 0.0024 17.8 0.0 4 7.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA PF00004.29 KPI42118.1 - 0.0033 17.9 0.0 0.0093 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) YfdX PF10938.8 KPI42118.1 - 0.027 14.4 0.1 2.1 8.3 0.0 3.6 3 1 0 3 3 3 0 YfdX protein NB-ARC PF00931.22 KPI42118.1 - 0.041 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 KPI42118.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_19 PF14559.6 KPI42118.1 - 0.049 14.2 2.8 21 5.7 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat AAA_19 PF13245.6 KPI42118.1 - 0.096 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIG-L PF02585.17 KPI42118.1 - 0.12 13.0 0.1 0.42 11.2 0.1 2.1 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase TPR_6 PF13174.6 KPI42118.1 - 0.16 12.7 1.2 4.2e+02 1.9 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_28 PF13521.6 KPI42118.1 - 0.38 11.0 1.8 1.6 8.9 0.0 3.0 4 0 0 4 4 3 0 AAA domain TPR_14 PF13428.6 KPI42118.1 - 7.2 7.7 9.7 36 5.6 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat MmgE_PrpD PF03972.14 KPI42119.1 - 1e-105 353.9 8.7 1.2e-105 353.7 8.7 1.0 1 0 0 1 1 1 1 MmgE/PrpD family HPP PF04982.13 KPI42119.1 - 5.9 7.1 7.1 0.47 10.6 1.2 2.2 2 1 0 2 2 2 0 HPP family Vac_ImportDeg PF09783.9 KPI42120.1 - 1.7e-61 206.7 0.5 2.3e-61 206.3 0.5 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein adh_short PF00106.25 KPI42121.1 - 2.4e-21 76.1 0.0 3.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42121.1 - 1e-17 64.5 0.0 1.8e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 KPI42122.1 - 1.8e-07 31.2 10.3 1.8e-07 31.2 10.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ResIII PF04851.15 KPI42123.1 - 5.7e-25 88.3 0.0 1.4e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI42123.1 - 1.5e-18 67.2 0.2 5.3e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KPI42123.1 - 5.8e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KPI42123.1 - 0.00021 21.0 0.8 0.00036 20.3 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KPI42123.1 - 0.0014 17.9 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 KPI42123.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SwrA PF17423.2 KPI42123.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Swarming motility protein AAA_22 PF13401.6 KPI42123.1 - 0.041 14.2 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KPI42123.1 - 0.055 13.0 0.0 2.9 7.3 0.0 2.3 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Peptidase_M24 PF00557.24 KPI42124.1 - 5.7e-39 134.0 0.0 8.5e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KPI42124.1 - 1.3e-06 29.1 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Myb_DNA-binding PF00249.31 KPI42125.1 - 0.0011 19.1 0.0 0.0033 17.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SnAPC_2_like PF11035.8 KPI42125.1 - 0.0043 17.2 0.0 0.0043 17.2 0.0 2.6 2 1 0 2 2 2 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Tn7_Tnp_TnsA_C PF08721.11 KPI42125.1 - 0.12 13.1 0.8 13 6.5 0.0 2.8 2 0 0 2 2 2 0 TnsA endonuclease C terminal DUF327 PF03885.13 KPI42125.1 - 0.15 12.0 1.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Myb_DNA-bind_7 PF15963.5 KPI42125.1 - 0.46 10.4 0.0 0.46 10.4 0.0 2.5 3 0 0 3 3 3 0 Myb DNA-binding like Zn_clus PF00172.18 KPI42126.1 - 7.3e-06 26.0 7.9 1.3e-05 25.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI42126.1 - 0.0055 15.8 1.4 0.027 13.5 0.7 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.7 KPI42127.1 - 0.053 13.4 4.6 0.073 13.0 0.3 2.5 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.6 KPI42127.1 - 0.15 12.1 0.5 0.96 9.4 0.5 2.2 1 1 0 1 1 1 0 F-box-like domain Mid2 PF04478.12 KPI42128.1 - 0.0074 16.1 0.3 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rax2 PF12768.7 KPI42128.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 KPI42128.1 - 0.28 11.1 3.0 0.37 10.7 2.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family NAD_binding_8 PF13450.6 KPI42129.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 KPI42130.1 - 1.6e-06 27.7 0.0 2.7e-05 23.7 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain CCDC53 PF10152.9 KPI42130.1 - 8.8 6.7 8.8 3.5 8.0 5.8 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ribosomal_L30 PF00327.20 KPI42131.1 - 2.3e-15 56.2 0.1 3.2e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FAD_binding_3 PF01494.19 KPI42132.1 - 8.5e-13 48.3 0.0 1.7e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI42132.1 - 3.4e-11 42.9 0.3 1.2e-05 24.8 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI42132.1 - 4.1e-07 29.1 0.2 0.00058 18.7 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KPI42132.1 - 8.4e-07 29.1 0.2 2.1e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI42132.1 - 1.2e-06 28.0 0.8 2.1e-06 27.1 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPI42132.1 - 2.6e-05 23.8 1.2 4.8e-05 22.9 1.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI42132.1 - 4.2e-05 22.8 0.1 7.6e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KPI42132.1 - 5.2e-05 22.5 0.1 8.6e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KPI42132.1 - 6.4e-05 22.7 6.6 0.0011 18.6 1.9 2.7 1 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI42132.1 - 0.00016 22.1 0.1 0.01 16.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KPI42132.1 - 0.0032 17.4 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 KPI42132.1 - 0.043 13.2 0.0 0.074 12.5 0.0 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.17 KPI42132.1 - 0.093 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KPI42132.1 - 0.11 11.7 1.0 1.4 8.1 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KPI42133.1 - 0.00022 21.3 8.4 0.00045 20.3 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI42133.1 - 0.0065 15.5 0.2 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sen15 PF09631.10 KPI42134.1 - 2.9e-11 43.5 0.0 5.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein Zn_clus PF00172.18 KPI42136.1 - 4.3e-06 26.7 12.0 8.2e-06 25.8 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI42136.1 - 0.096 11.5 1.3 0.11 11.3 0.5 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain NIL PF09383.10 KPI42137.1 - 0.081 12.8 0.1 0.093 12.6 0.1 1.4 1 1 0 1 1 1 0 NIL domain Chordopox_L2 PF05803.12 KPI42137.1 - 0.15 11.9 1.5 0.19 11.6 1.5 1.2 1 0 0 1 1 1 0 Chordopoxvirus L2 protein DUF202 PF02656.15 KPI42137.1 - 0.23 11.9 1.9 0.53 10.8 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF3185 PF11381.8 KPI42137.1 - 0.56 10.3 5.6 0.58 10.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) YtpI PF14007.6 KPI42137.1 - 1.2 9.3 6.9 3 8.0 2.2 2.4 1 1 2 3 3 3 0 YtpI-like protein BCDHK_Adom3 PF10436.9 KPI42138.1 - 1.5e-06 28.2 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KPI42138.1 - 1.6e-06 28.6 0.0 7.6e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KPI42138.1 - 0.0066 16.4 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KPI42138.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAP PF00188.26 KPI42139.1 - 1.5e-19 71.0 2.4 3e-19 70.1 2.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EBP50_C PF09007.11 KPI42139.1 - 0.12 13.3 5.2 0.21 12.6 5.2 1.3 1 0 0 1 1 1 0 EBP50, C-terminal Shisa PF13908.6 KPI42139.1 - 0.7 10.1 4.2 1.2 9.4 4.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pex14_N PF04695.13 KPI42139.1 - 1.9 9.1 10.0 3 8.5 10.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nucleo_P87 PF07267.11 KPI42139.1 - 2 7.1 5.1 2.5 6.8 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 p450 PF00067.22 KPI42140.1 - 5.5e-48 163.9 0.0 1.1e-47 162.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Thymidylate_kin PF02223.17 KPI42141.1 - 6.6e-43 146.5 0.0 7.7e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CPT PF07931.12 KPI42141.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein TolA_bind_tri PF16331.5 KPI42141.1 - 0.022 14.8 0.4 0.048 13.7 0.4 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation KTI12 PF08433.10 KPI42141.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KPI42141.1 - 0.17 12.4 0.0 0.34 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_26 PF13500.6 KPI42141.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pga1 PF10333.9 KPI42142.1 - 7.7e-08 32.4 2.2 1.9e-07 31.1 2.2 1.7 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Sugar_tr PF00083.24 KPI42143.1 - 2.7e-96 323.2 25.5 3.3e-96 322.9 25.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42143.1 - 1.6e-17 63.5 30.1 1.6e-17 63.5 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI42143.1 - 0.19 10.5 15.9 0.94 8.3 6.9 2.2 2 0 0 2 2 2 0 MFS_1 like family ADH_N PF08240.12 KPI42144.1 - 2.9e-16 59.3 1.1 5.7e-16 58.4 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI42144.1 - 1.1e-13 51.3 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KPI42144.1 - 0.0034 17.2 0.2 0.0073 16.1 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI42144.1 - 0.0049 17.5 0.2 0.015 16.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPI42144.1 - 0.0081 16.2 0.1 0.059 13.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI42144.1 - 0.01 16.5 0.1 0.034 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KPI42144.1 - 0.12 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KPI42144.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) WD40 PF00400.32 KPI42145.1 - 2.2e-38 129.5 27.7 1.2e-08 35.4 0.1 12.0 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.12 KPI42145.1 - 6.6e-20 71.4 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KPI42145.1 - 9.1e-16 57.9 0.0 0.49 10.7 0.0 9.6 4 2 6 10 10 10 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI42145.1 - 2.8e-08 33.1 0.1 0.31 9.9 0.0 4.8 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KPI42145.1 - 0.0069 15.0 0.0 0.29 9.6 0.0 2.8 3 0 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 KPI42145.1 - 0.0075 15.6 0.1 0.5 9.6 0.0 2.7 3 0 0 3 3 3 1 WD40-like domain DUF5074 PF16819.5 KPI42145.1 - 0.19 11.8 0.1 7.6 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5074) PD40 PF07676.12 KPI42145.1 - 8.9 6.4 14.8 31 4.6 0.1 6.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 KPI42146.1 - 7.7e-34 117.2 49.7 6.3e-32 110.9 32.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 KPI42146.1 - 0.13 12.9 1.8 22 5.7 0.1 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Phage_holin_3_6 PF07332.11 KPI42146.1 - 0.4 10.8 0.0 0.4 10.8 0.0 3.6 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III AtuA PF07287.11 KPI42147.1 - 1.2e-127 425.5 0.0 1.4e-127 425.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA RmlD_sub_bind PF04321.17 KPI42148.1 - 9.1e-61 205.5 0.8 1.1e-60 205.2 0.8 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KPI42148.1 - 2e-28 99.5 0.1 2.5e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI42148.1 - 1.9e-14 53.8 1.6 2.1e-13 50.4 1.6 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPI42148.1 - 3.5e-11 42.8 6.3 6e-10 38.7 0.7 3.3 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KPI42148.1 - 3.4e-09 36.3 0.3 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KPI42148.1 - 3.9e-08 32.6 0.7 2.9e-07 29.8 0.7 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPI42148.1 - 1.5e-05 24.9 1.6 4.9e-05 23.3 1.6 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KPI42148.1 - 0.013 15.4 1.5 2.7 7.9 0.2 2.5 1 1 1 2 2 2 0 KR domain NmrA PF05368.13 KPI42148.1 - 0.015 14.9 0.2 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 KPI42148.1 - 0.021 14.3 0.3 0.049 13.1 0.3 1.7 1 1 0 1 1 1 0 short chain dehydrogenase AP_endonuc_2 PF01261.24 KPI42148.1 - 0.092 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel UBA PF00627.31 KPI42148.1 - 1 9.3 3.8 16 5.5 0.1 3.2 3 0 0 3 3 3 0 UBA/TS-N domain DUF2614 PF11023.8 KPI42149.1 - 1.7 8.7 8.5 0.27 11.4 0.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain adh_short_C2 PF13561.6 KPI42150.1 - 1.2e-37 129.7 1.8 8.3e-37 127.0 1.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42150.1 - 8.7e-28 97.1 2.5 2e-27 95.9 2.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42150.1 - 3.1e-07 30.5 1.8 1.1e-06 28.7 0.2 1.9 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KPI42150.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sdh_cyt PF01127.22 KPI42151.1 - 3.8e-24 85.0 5.0 5.7e-24 84.5 5.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short_C2 PF13561.6 KPI42152.1 - 6.9e-34 117.4 0.2 8.4e-34 117.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42152.1 - 6e-21 74.8 0.3 7.6e-21 74.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42152.1 - 2.7e-05 24.1 0.2 4e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Gtr1_RagA PF04670.12 KPI42153.1 - 5.3e-90 300.8 0.0 6.7e-90 300.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KPI42153.1 - 2.8e-09 37.2 0.1 7e-09 36.0 0.0 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KPI42153.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KPI42153.1 - 2e-07 31.1 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KPI42153.1 - 2.4e-06 27.1 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KPI42153.1 - 0.0057 15.9 4.3 0.97 8.5 1.2 2.7 2 1 1 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 KPI42153.1 - 0.0071 15.9 0.0 0.023 14.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KPI42153.1 - 0.012 15.4 1.5 0.052 13.3 0.7 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KPI42153.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 KPI42153.1 - 0.016 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KPI42153.1 - 0.016 15.2 0.1 0.045 13.8 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_10 PF12846.7 KPI42153.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.13 KPI42153.1 - 0.031 13.5 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KPI42153.1 - 0.037 13.9 1.1 0.23 11.4 0.1 2.5 3 0 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 KPI42153.1 - 0.097 12.0 0.3 0.25 10.6 0.3 1.9 1 1 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 KPI42153.1 - 0.12 12.8 0.2 0.22 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KPI42153.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain SecA_SW PF07516.13 KPI42153.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 SecA Wing and Scaffold domain LCCL PF03815.19 KPI42154.1 - 7.4e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF3995 PF13160.6 KPI42154.1 - 0.46 10.9 5.3 0.32 11.4 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) ADH_N PF08240.12 KPI42155.1 - 8.8e-21 73.8 4.1 1.7e-20 72.9 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI42155.1 - 1e-06 28.7 0.1 1.7e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 KPI42156.1 - 3.9e-21 75.3 0.0 1.7e-20 73.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PepX_C PF08530.10 KPI42157.1 - 2.4e-31 109.4 0.1 3e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Rad10 PF03834.14 KPI42158.1 - 2.5e-48 162.8 0.2 3.5e-48 162.3 0.2 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KPI42158.1 - 0.00019 22.0 0.0 0.00036 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KPI42158.1 - 0.0082 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KPI42158.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zn_clus PF00172.18 KPI42159.1 - 5.3e-08 32.8 9.1 1e-07 32.0 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like_2 PF13013.6 KPI42160.1 - 0.00018 21.4 0.0 0.00075 19.4 0.0 2.0 1 1 0 1 1 1 1 F-box-like domain DUF4864 PF16156.5 KPI42160.1 - 0.069 13.9 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) F-box-like PF12937.7 KPI42160.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 F-box-like Glyco_hydro_3_C PF01915.22 KPI42161.1 - 6.5e-47 160.1 0.0 1.4e-46 159.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI42161.1 - 3.5e-35 121.9 0.0 6.7e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI42161.1 - 4.1e-21 74.9 0.3 7.3e-21 74.1 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CDC45 PF02724.14 KPI42162.1 - 3.1 6.0 9.3 3.9 5.7 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein EMP24_GP25L PF01105.24 KPI42164.1 - 1.7e-49 168.2 0.1 2e-49 168.0 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ACT_7 PF13840.6 KPI42165.1 - 3.2e-28 97.3 0.0 4e-16 58.6 0.0 2.7 2 1 0 2 2 2 2 ACT domain p450 PF00067.22 KPI42167.1 - 5e-51 173.9 0.0 6.1e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 XFP_N PF09364.10 KPI42168.1 - 6.8e-143 475.9 0.9 2.8e-141 470.6 0.9 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KPI42168.1 - 3.1e-76 255.0 0.1 5.4e-76 254.2 0.1 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KPI42168.1 - 5.5e-76 254.5 0.0 8.7e-76 253.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 KPI42168.1 - 0.035 13.9 0.3 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 KPI42168.1 - 0.14 12.1 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Transketolase, C-terminal domain AA_permease PF00324.21 KPI42169.1 - 3.9e-110 368.7 36.0 4.8e-110 368.4 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI42169.1 - 1.7e-17 63.4 39.3 2.4e-17 62.9 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 KPI42169.1 - 0.0093 16.3 1.5 0.0093 16.3 1.5 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1772) Dioxygenase_C PF00775.21 KPI42170.1 - 2.4e-44 151.0 0.0 4e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KPI42170.1 - 9.8e-28 95.8 0.1 1.8e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Fungal_trans PF04082.18 KPI42170.1 - 3.1e-11 42.8 0.0 7.4e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SpaA PF17802.1 KPI42170.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Prealbumin-like fold domain 2OG-Fe_Oxy_2 PF10014.9 KPI42170.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe dioxygenase MTHFR PF02219.17 KPI42172.1 - 8.8e-75 251.7 0.0 5.3e-73 245.8 0.0 2.2 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase BCS1_N PF08740.11 KPI42173.1 - 9.4e-19 68.1 2.0 1.5e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KPI42173.1 - 7.2e-16 58.8 0.0 4.3e-15 56.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.6 KPI42173.1 - 0.00038 20.8 19.2 0.25 11.7 8.3 3.4 3 0 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_16 PF13191.6 KPI42173.1 - 0.0018 18.7 0.0 0.005 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KPI42173.1 - 0.012 16.1 0.2 0.058 13.9 0.0 2.0 2 1 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.17 KPI42173.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KPI42173.1 - 0.025 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KPI42173.1 - 0.027 14.9 0.0 0.1 13.0 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KPI42173.1 - 0.035 14.1 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 KPI42173.1 - 0.04 12.8 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_25 PF13481.6 KPI42173.1 - 0.043 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPI42173.1 - 0.047 13.4 0.2 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KPI42173.1 - 0.052 13.3 0.3 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Parvo_NS1 PF01057.17 KPI42173.1 - 0.064 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 KPI42173.1 - 0.077 12.3 0.1 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 KaiC V-ATPase_G PF03179.15 KPI42173.1 - 0.079 13.5 5.8 0.18 12.3 5.8 1.6 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF815 PF05673.13 KPI42173.1 - 0.083 12.0 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KPI42173.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain RP-C_C PF11800.8 KPI42173.1 - 0.1 12.7 1.3 0.19 11.8 1.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region TIP49 PF06068.13 KPI42173.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KPI42173.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.4 2 1 0 2 2 1 0 AAA domain DUF1045 PF06299.12 KPI42173.1 - 0.2 11.6 0.8 0.41 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) AAA_11 PF13086.6 KPI42173.1 - 0.29 10.9 6.9 1.5 8.6 6.9 1.9 1 1 0 1 1 1 0 AAA domain DUF3987 PF13148.6 KPI42173.1 - 0.69 8.9 5.2 2.7 6.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 KPI42173.1 - 3 8.3 9.1 1.2e+02 3.0 9.1 2.4 1 1 0 1 1 1 0 AAA domain LIP PF03583.14 KPI42174.1 - 2.9e-12 46.5 0.2 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.8 KPI42174.1 - 0.071 12.4 0.1 0.75 9.0 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KPI42174.1 - 0.23 9.9 0.2 1.3 7.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1295 PF06966.12 KPI42175.1 - 1.4e-21 77.1 2.8 1.4e-21 77.1 1.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KPI42175.1 - 0.026 14.5 1.7 0.064 13.2 1.0 1.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Fungal_trans_2 PF11951.8 KPI42176.1 - 2.8e-05 23.1 0.0 8.1e-05 21.6 0.1 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF3208 PF11482.8 KPI42176.1 - 0.086 13.2 0.0 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) F-box PF00646.33 KPI42177.1 - 1e-05 25.3 0.4 4.1e-05 23.3 0.4 2.1 1 0 0 1 1 1 1 F-box domain FAD_binding_4 PF01565.23 KPI42178.1 - 2.4e-19 69.4 1.4 4.7e-19 68.5 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI42178.1 - 3.8e-10 39.7 0.0 7.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PGA2 PF07543.12 KPI42180.1 - 0.9 9.5 6.7 1.8 8.5 6.7 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DJ-1_PfpI PF01965.24 KPI42181.1 - 2.7e-08 33.8 0.0 1.7e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 DJ-1/PfpI family bZIP_1 PF00170.21 KPI42182.1 - 0.034 14.2 5.4 0.061 13.4 5.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor UPF0242 PF06785.11 KPI42182.1 - 0.042 14.0 0.1 0.042 14.0 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF465 PF04325.13 KPI42182.1 - 0.59 10.2 2.2 0.44 10.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF465) bZIP_2 PF07716.15 KPI42182.1 - 3.4 7.8 9.0 9.6 6.4 6.3 2.2 1 1 1 2 2 2 0 Basic region leucine zipper SOG2 PF10428.9 KPI42185.1 - 0.5 9.5 20.2 0.59 9.3 20.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short_C2 PF13561.6 KPI42186.1 - 8.6e-41 140.0 0.1 1.7e-40 139.0 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42186.1 - 6e-36 123.7 0.5 1.4e-35 122.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RWD PF05773.22 KPI42186.1 - 2.9e-20 72.7 0.0 7.6e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 RWD domain KR PF08659.10 KPI42186.1 - 0.035 14.0 0.6 0.085 12.8 0.1 1.8 2 0 0 2 2 2 0 KR domain DFRP_C PF16543.5 KPI42186.1 - 0.61 10.6 11.1 1 9.9 10.3 1.8 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Acetyltransf_1 PF00583.25 KPI42187.1 - 1.5e-11 44.6 0.0 2.7e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI42187.1 - 1e-09 38.7 0.1 1.5e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI42187.1 - 1.7e-09 37.7 0.0 2.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI42187.1 - 0.0033 17.4 0.0 0.008 16.1 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein DIOX_N PF14226.6 KPI42188.1 - 1.6e-22 80.4 0.1 2.8e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI42188.1 - 8.6e-17 61.5 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Stb3 PF10330.9 KPI42189.1 - 6.8e-38 128.6 0.0 1.1e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Pectate_lyase_3 PF12708.7 KPI42190.1 - 2.6e-81 272.6 15.1 2.2e-70 236.9 3.0 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KPI42190.1 - 2.6e-06 27.0 2.4 0.042 13.5 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Septin PF00735.18 KPI42191.1 - 9.4e-113 376.2 0.2 1.3e-112 375.7 0.2 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KPI42191.1 - 4e-08 33.3 0.0 8.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI42191.1 - 3.5e-06 27.0 0.1 2.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KPI42191.1 - 4.4e-05 23.1 3.8 0.00011 21.8 0.3 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KPI42191.1 - 0.0024 18.1 0.1 0.0051 17.0 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KPI42191.1 - 0.0042 16.6 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 KPI42191.1 - 0.0043 17.3 0.8 0.012 15.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 KPI42191.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_24 PF13479.6 KPI42191.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KPI42191.1 - 0.012 15.2 0.3 0.043 13.4 0.2 2.0 2 0 0 2 2 2 0 Ras family IIGP PF05049.13 KPI42191.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.6 KPI42191.1 - 0.017 14.7 0.1 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KPI42191.1 - 0.024 13.9 0.0 0.028 13.7 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KPI42191.1 - 0.025 15.0 0.1 0.096 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KPI42191.1 - 0.032 14.7 0.3 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter FOXP-CC PF16159.5 KPI42191.1 - 0.04 14.6 0.7 0.13 12.9 0.2 2.2 1 1 1 2 2 1 0 FOXP coiled-coil domain T2SSE PF00437.20 KPI42191.1 - 0.05 12.7 0.5 0.12 11.4 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KPI42191.1 - 0.052 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KPI42191.1 - 0.097 12.4 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KPI42191.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 KPI42191.1 - 0.13 12.0 0.5 5.1 6.8 0.5 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KPI42191.1 - 0.3 10.8 1.0 11 5.7 0.1 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KPI42191.1 - 0.43 10.6 5.5 2.7 8.0 0.1 2.8 2 1 1 3 3 3 0 Dynamin family RRM_1 PF00076.22 KPI42193.1 - 3e-15 55.8 0.0 1.5e-06 27.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WaaY PF06176.11 KPI42194.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Aldo_ket_red PF00248.21 KPI42195.1 - 1.2e-52 179.0 0.0 3.9e-50 170.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Rrn6 PF10214.9 KPI42196.1 - 1.8e-73 248.5 12.8 7.3e-45 153.8 0.1 2.0 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Tim54 PF11711.8 KPI42197.1 - 7.2e-137 456.1 0.1 8.5e-137 455.9 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Asp_Arg_Hydrox PF05118.15 KPI42197.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase CTD_bind PF04818.13 KPI42199.1 - 2.8e-08 34.4 0.0 6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KPI42199.1 - 2e-05 24.3 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.9 KPI42199.1 - 0.9 8.6 8.0 1.6 7.8 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF5570 PF17731.1 KPI42200.1 - 0.087 12.9 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5570) DUF2888 PF11135.8 KPI42200.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Aminotran_1_2 PF00155.21 KPI42201.1 - 2.5e-06 26.9 0.0 1.1e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.11 KPI42201.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase IBR PF01485.21 KPI42202.1 - 5.3e-11 42.6 34.6 2.4e-08 34.0 8.3 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KPI42202.1 - 0.00022 21.2 7.3 0.00022 21.2 7.3 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KPI42202.1 - 0.00034 20.9 6.5 0.00034 20.9 6.5 4.8 2 1 2 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KPI42202.1 - 0.00035 20.5 7.2 0.00035 20.5 7.2 4.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 KPI42202.1 - 0.0022 17.7 7.1 0.013 15.3 5.8 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI42202.1 - 0.01 15.7 7.0 0.01 15.7 7.0 4.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PAM2 PF07145.15 KPI42203.1 - 7.5e-05 22.1 16.6 0.16 11.7 0.2 5.2 5 0 0 5 5 5 4 Ataxin-2 C-terminal region TPR_MLP1_2 PF07926.12 KPI42203.1 - 0.001 19.1 15.8 0.001 19.1 15.8 8.2 5 1 3 8 8 8 2 TPR/MLP1/MLP2-like protein Zn_clus PF00172.18 KPI42204.1 - 1.8e-05 24.7 14.2 3.2e-05 24.0 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI42204.1 - 0.00055 18.8 2.7 0.00055 18.8 2.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ysc84 PF04366.12 KPI42205.1 - 1.8e-42 144.1 0.1 3.3e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator MMR_HSR1_Xtn PF16897.5 KPI42206.1 - 1.4e-34 118.3 0.7 6.4e-34 116.2 0.2 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KPI42206.1 - 1.9e-21 76.3 0.0 4e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KPI42206.1 - 1.5e-20 73.0 0.0 2.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KPI42206.1 - 5e-14 52.1 0.0 8.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPI42206.1 - 0.00016 21.8 0.2 0.21 11.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KPI42206.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 KPI42206.1 - 0.087 11.8 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KPI42206.1 - 0.12 12.6 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase OsmC PF02566.19 KPI42207.1 - 1.8e-18 66.8 0.0 4.4e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 OsmC-like protein adh_short_C2 PF13561.6 KPI42208.1 - 4.2e-34 118.1 0.0 5e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42208.1 - 3.6e-22 78.8 0.0 4.7e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42208.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KPI42208.1 - 3.1e-05 24.4 0.0 0.00019 21.8 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.21 KPI42208.1 - 0.0001 21.9 0.1 0.00032 20.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI42208.1 - 0.00045 19.7 0.0 0.00059 19.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KPI42208.1 - 0.009 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 KPI42208.1 - 0.011 15.1 0.3 0.019 14.3 0.3 1.3 1 0 0 1 1 1 0 ThiF family THF_DHG_CYH_C PF02882.19 KPI42208.1 - 0.017 14.4 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3895 PF13034.6 KPI42208.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) LpxI_N PF17930.1 KPI42208.1 - 0.055 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain YjeF_N PF03853.15 KPI42208.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KPI42208.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KPI42208.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KPI42208.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KPI42208.1 - 0.13 12.9 0.4 0.67 10.6 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent INTS5_N PF14837.6 KPI42208.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Mg_trans_NIPA PF05653.14 KPI42209.1 - 2e-65 220.8 7.4 2.3e-62 210.8 5.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA SLC35F PF06027.12 KPI42209.1 - 0.031 13.8 0.1 0.031 13.8 0.1 2.2 1 1 1 2 2 2 0 Solute carrier family 35 EamA PF00892.20 KPI42209.1 - 0.032 14.4 0.6 0.032 14.4 0.6 3.6 3 1 0 3 3 3 0 EamA-like transporter family LRR19-TM PF15176.6 KPI42209.1 - 0.033 14.2 0.2 13 5.8 0.4 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LysE PF01810.18 KPI42209.1 - 0.55 9.7 8.0 0.034 13.6 1.0 2.5 2 1 1 3 3 3 0 LysE type translocator DUF2070 PF09843.9 KPI42209.1 - 4.4 5.5 9.2 6.1 5.0 9.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2052 PF09747.9 KPI42210.1 - 2.6e-24 86.5 16.4 9.3e-13 48.7 10.5 2.2 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Sugar_tr PF00083.24 KPI42212.1 - 7e-85 285.6 33.3 8.2e-85 285.3 33.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42212.1 - 5.5e-13 48.6 43.8 5.7e-12 45.2 10.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Smr PF01713.21 KPI42212.1 - 0.18 12.2 0.2 1.1 9.6 0.0 2.3 3 0 0 3 3 3 0 Smr domain FGGY_C PF02782.16 KPI42213.1 - 1.3e-47 162.1 0.5 2e-47 161.5 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KPI42213.1 - 2e-21 76.7 0.8 6.4e-19 68.5 0.2 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KPI42213.1 - 0.046 13.2 0.2 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RPAP2_Rtr1 PF04181.13 KPI42214.1 - 2.1e-17 63.2 0.4 3.6e-17 62.5 0.4 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family ABC_membrane PF00664.23 KPI42215.1 - 8.5e-106 353.6 37.6 2.7e-53 181.4 16.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI42215.1 - 4.6e-66 221.5 0.0 2.4e-32 112.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI42215.1 - 3.8e-16 59.2 0.0 1.4e-05 24.7 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI42215.1 - 1e-06 28.4 0.4 0.0058 16.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KPI42215.1 - 1.9e-06 27.0 1.7 0.024 13.5 0.1 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KPI42215.1 - 5.7e-06 26.8 0.8 0.16 12.4 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KPI42215.1 - 3.5e-05 24.1 4.6 0.5 10.6 0.0 4.4 4 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KPI42215.1 - 6.4e-05 22.9 0.1 0.21 11.5 0.0 3.1 3 0 0 3 3 2 2 RsgA GTPase AAA_25 PF13481.6 KPI42215.1 - 0.00011 21.8 0.0 0.085 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KPI42215.1 - 0.00019 21.4 1.7 2.5 7.8 0.0 3.7 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KPI42215.1 - 0.0013 18.5 5.3 0.29 10.8 0.1 3.9 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KPI42215.1 - 0.0026 17.5 0.2 4 7.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain G-alpha PF00503.20 KPI42215.1 - 0.003 16.8 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 KPI42215.1 - 0.0032 17.6 0.3 1.6 8.8 0.1 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 KPI42215.1 - 0.0095 16.2 0.1 1.4 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KPI42215.1 - 0.011 16.2 0.0 8.8 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KPI42215.1 - 0.014 15.9 0.2 2.7 8.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.6 KPI42215.1 - 0.015 15.6 6.8 2.3 8.5 0.2 4.2 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KPI42215.1 - 0.015 15.4 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPI42215.1 - 0.019 14.5 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2852 PF11014.8 KPI42215.1 - 0.02 15.0 1.0 5.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) AAA_5 PF07728.14 KPI42215.1 - 0.021 14.8 0.4 14 5.6 0.0 3.4 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KPI42215.1 - 0.022 14.0 1.2 5.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin PRK PF00485.18 KPI42215.1 - 0.055 13.2 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KPI42215.1 - 0.056 13.1 0.3 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KPI42215.1 - 0.12 12.0 0.2 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain HET PF06985.11 KPI42216.1 - 1.2e-31 110.1 0.5 1.2e-31 110.1 0.5 2.9 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) DUF4363 PF14276.6 KPI42216.1 - 0.17 12.0 1.0 0.33 11.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) NPR3 PF03666.13 KPI42216.1 - 4.4 6.0 7.3 6.6 5.4 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SSF PF00474.17 KPI42217.1 - 4.1e-20 72.0 20.7 4.1e-20 72.0 20.7 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family 7tm_7 PF08395.12 KPI42217.1 - 0.0084 15.4 0.4 0.0084 15.4 0.4 2.7 3 0 0 3 3 3 1 7tm Chemosensory receptor Peptidase_S41 PF03572.18 KPI42218.1 - 0.00026 20.6 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 LisH PF08513.11 KPI42219.1 - 1.2e-09 37.8 0.7 1.4e-05 24.9 0.0 3.1 3 0 0 3 3 3 2 LisH Zn_clus PF00172.18 KPI42219.1 - 0.00019 21.5 5.3 0.00031 20.8 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LisH_2 PF16045.5 KPI42219.1 - 0.0079 15.2 0.0 0.042 12.9 0.0 1.9 2 0 0 2 2 2 1 LisH RCC1 PF00415.18 KPI42220.1 - 2.1e-52 175.5 12.0 3.3e-11 43.6 0.3 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KPI42220.1 - 5e-35 118.6 27.9 1.9e-09 37.1 1.4 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Presenilin PF01080.17 KPI42220.1 - 6.2 5.5 5.6 8.2 5.1 5.6 1.1 1 0 0 1 1 1 0 Presenilin Mgm101p PF06420.12 KPI42221.1 - 2.7e-88 293.9 0.0 4e-88 293.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 KPI42221.1 - 4.5e-06 26.7 7.0 1.4e-05 25.1 7.0 1.9 1 0 0 1 1 1 1 CHCH domain Phosphodiest PF01663.22 KPI42222.1 - 9.6e-16 58.3 1.6 2.3e-10 40.6 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPI42222.1 - 0.069 12.5 0.8 0.18 11.2 0.0 2.1 3 0 0 3 3 3 0 Sulfatase zf-CCCH_2 PF14608.6 KPI42223.1 - 0.042 14.3 10.9 0.98 10.0 1.9 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Stathmin PF00836.19 KPI42223.1 - 0.086 12.8 0.5 0.28 11.1 0.5 1.9 1 1 0 1 1 1 0 Stathmin family zf-CCCH PF00642.24 KPI42223.1 - 0.24 11.4 10.1 16 5.5 0.2 3.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3746 PF12562.8 KPI42223.1 - 0.34 10.9 1.4 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) DUF16 PF01519.16 KPI42223.1 - 0.7 10.4 4.4 0.25 11.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 T3SSipB PF16535.5 KPI42223.1 - 9.8 6.6 8.7 0.21 12.1 1.2 2.1 3 0 0 3 3 3 0 Type III cell invasion protein SipB Gly_transf_sug PF04488.15 KPI42224.1 - 5.5e-14 52.6 0.0 1.6e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif zf-met2 PF12907.7 KPI42225.1 - 9.4e-14 51.3 0.3 1.4e-13 50.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KPI42225.1 - 2.8e-07 31.3 9.5 4e-07 30.8 9.5 1.2 1 0 0 1 1 1 1 4F5 protein family Prot_ATP_ID_OB PF16450.5 KPI42226.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain p450 PF00067.22 KPI42227.1 - 9.9e-56 189.4 0.0 1.4e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KPI42228.1 - 3.4e-48 164.4 1.1 4.7e-48 163.9 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 KPI42228.1 - 6.2e-46 156.9 0.0 1.6e-45 155.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI42228.1 - 0.00011 21.3 0.2 0.00034 19.6 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family DUF4404 PF14357.6 KPI42228.1 - 0.026 15.1 0.2 0.23 12.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HpcH_HpaI PF03328.14 KPI42229.1 - 5.2e-26 91.2 0.0 6.8e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.22 KPI42230.1 - 1e-66 225.6 0.0 1.2e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KPI42231.1 - 7.3e-21 74.8 0.1 9.1e-20 71.2 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI42231.1 - 9.8e-08 32.1 0.7 3.2e-07 30.5 0.4 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI42231.1 - 3e-07 30.0 0.1 5.7e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI42231.1 - 5.3e-06 25.8 0.8 7.8e-06 25.2 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI42231.1 - 5.3e-06 26.2 0.5 7.7e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI42231.1 - 1.5e-05 24.3 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KPI42231.1 - 7.9e-05 22.2 0.0 9.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI42231.1 - 0.00038 21.0 0.0 0.0038 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI42231.1 - 0.00084 18.5 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPI42231.1 - 0.01 14.5 0.8 0.021 13.5 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 KPI42231.1 - 0.012 14.9 0.9 0.043 13.1 0.2 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KPI42231.1 - 0.034 13.0 0.2 0.68 8.7 0.1 2.6 2 1 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KPI42231.1 - 0.062 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KPI42231.1 - 0.13 12.2 0.7 0.53 10.3 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KPI42231.1 - 0.15 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KPI42231.1 - 0.17 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KPI42231.1 - 0.23 10.7 0.6 0.6 9.3 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KPI42232.1 - 8e-78 262.3 24.3 9.7e-78 262.0 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42232.1 - 5.3e-26 91.4 40.6 1.1e-24 87.1 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 KPI42233.1 - 1.6e-26 93.3 0.0 2e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Orthopox_A36R PF05950.11 KPI42233.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Amidohydro_1 PF01979.20 KPI42234.1 - 7.3e-16 58.4 1.8 9e-16 58.1 1.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI42234.1 - 5.3e-08 32.8 4.0 0.0005 19.6 0.7 2.9 1 1 1 2 2 2 2 Amidohydrolase family WD40 PF00400.32 KPI42235.1 - 2.2e-24 85.2 12.0 3.9e-05 24.3 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI42235.1 - 6.7e-15 55.2 3.7 1.4e-05 25.3 0.1 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KPI42235.1 - 1.1e-07 32.0 0.2 0.021 14.7 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KPI42235.1 - 0.0069 15.4 0.0 0.032 13.2 0.0 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactamase_B_6 PF16661.5 KPI42236.1 - 1.1e-63 214.2 0.0 2.3e-63 213.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KPI42236.1 - 1.2e-14 54.6 0.1 2.5e-13 50.3 0.0 2.7 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KPI42236.1 - 7.7e-12 45.0 0.0 1.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF100_C PF13299.6 KPI42236.1 - 5.6e-10 39.7 0.3 5.6e-10 39.7 0.3 3.0 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Treacle PF03546.14 KPI42236.1 - 0.33 9.7 7.6 3.5 6.3 0.2 2.8 3 0 0 3 3 3 0 Treacher Collins syndrome protein Treacle adh_short_C2 PF13561.6 KPI42237.1 - 4.7e-64 216.1 1.3 6.9e-64 215.6 1.3 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42237.1 - 6.1e-52 175.9 0.7 9e-52 175.4 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42237.1 - 2e-11 44.1 1.5 1.9e-10 40.9 1.5 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI42237.1 - 5e-07 29.2 0.1 3.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI42237.1 - 0.00054 19.5 0.1 0.00073 19.1 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KPI42237.1 - 0.012 15.7 0.3 0.023 14.8 0.3 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KPI42237.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FA_hydroxylase PF04116.13 KPI42238.1 - 1.7e-24 86.7 18.6 2e-24 86.5 15.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily F-box-like PF12937.7 KPI42240.1 - 5.7e-10 38.9 1.0 1.2e-09 37.9 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI42240.1 - 2.3e-09 36.9 0.5 4.4e-09 36.0 0.5 1.5 1 0 0 1 1 1 1 F-box domain TPP_enzyme_N PF02776.18 KPI42241.1 - 2.6e-25 89.0 0.1 4.7e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI42241.1 - 2e-18 66.4 0.0 4.7e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KPI42241.1 - 5.1e-18 65.3 0.0 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UCH PF00443.29 KPI42242.1 - 2.3e-46 158.4 0.0 3.1e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI42242.1 - 5.3e-11 42.7 2.4 1.3e-06 28.2 0.4 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KPI42242.1 - 0.0022 17.7 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DASH_Spc19 PF08287.11 KPI42242.1 - 0.44 10.4 16.8 12 5.8 0.0 2.7 2 1 0 2 2 2 0 Spc19 Anoctamin PF04547.12 KPI42243.1 - 8.7e-95 318.2 5.3 1.2e-94 317.7 5.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Sugar_tr PF00083.24 KPI42244.1 - 2.4e-70 237.7 18.1 2e-60 204.9 13.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42244.1 - 6.1e-14 51.7 29.1 8.4e-12 44.7 18.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 KPI42245.1 - 9.7e-29 100.6 1.3 1.7e-28 99.8 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Raffinose_syn PF05691.12 KPI42247.1 - 1.8e-55 188.1 0.1 7.7e-49 166.2 0.1 3.3 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Aldo_ket_red PF00248.21 KPI42248.1 - 1.2e-44 152.7 0.0 2.2e-42 145.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 KPI42248.1 - 0.006 15.9 0.8 3.1 7.3 0.3 2.9 3 0 0 3 3 3 2 Poliovirus 3A protein like MFS_1 PF07690.16 KPI42249.1 - 1.1e-35 123.2 28.4 9.1e-34 116.9 31.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily YfhO PF09586.10 KPI42249.1 - 0.14 10.3 0.8 0.35 9.1 0.8 1.6 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CNH PF00780.22 KPI42250.1 - 1.1e-64 218.7 0.0 1.7e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KPI42250.1 - 1.1e-26 94.2 0.1 4.6e-26 92.2 0.1 2.0 1 1 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KPI42250.1 - 1.9e-05 24.8 0.0 7.1e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Porin_3 PF01459.22 KPI42252.1 - 2.3e-74 250.2 0.0 2.8e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin ADH_N PF08240.12 KPI42253.1 - 5.9e-05 22.9 0.8 0.00035 20.4 0.4 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 KPI42254.1 - 0.041 14.4 0.1 0.26 11.8 0.1 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase RRM_1 PF00076.22 KPI42255.1 - 8.7e-19 67.1 0.0 1.4e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI42255.1 - 0.025 14.4 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif MBOAT_2 PF13813.6 KPI42256.1 - 4.7e-13 49.2 0.3 1.9e-12 47.2 0.3 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-C2H2 PF00096.26 KPI42257.1 - 1.1e-12 47.7 15.7 6.5e-05 23.2 2.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI42257.1 - 5.9e-07 29.8 13.0 0.014 16.2 2.2 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPI42257.1 - 1.7e-06 28.2 1.2 1.7e-06 28.2 1.2 4.8 4 1 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KPI42257.1 - 0.0052 17.1 1.5 0.29 11.6 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KPI42257.1 - 0.0055 17.0 5.5 0.0065 16.8 3.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KPI42257.1 - 0.026 15.1 4.3 0.077 13.6 0.6 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KPI42257.1 - 8.4 6.5 11.0 9.7 6.3 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Acyl-CoA_dh_1 PF00441.24 KPI42258.1 - 2.4e-19 70.0 0.6 2e-18 67.1 0.6 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI42258.1 - 1.2e-17 63.8 0.0 2.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI42258.1 - 2.9e-13 50.5 0.0 6.8e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPI42258.1 - 5.3e-10 39.7 0.3 9e-10 38.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_1 PF00561.20 KPI42259.1 - 2.6e-26 92.8 0.3 4.9e-26 91.9 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KPI42259.1 - 7e-22 76.8 0.0 1.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KPI42259.1 - 9.2e-06 25.1 0.0 0.0049 16.2 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KPI42259.1 - 0.0018 17.9 0.0 0.94 9.1 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KPI42259.1 - 0.13 12.1 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TMEM238 PF15125.6 KPI42259.1 - 0.19 11.9 0.8 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 TMEM238 protein family NAD_binding_11 PF14833.6 KPI42260.1 - 1.5e-31 109.1 0.0 2.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KPI42260.1 - 4.8e-30 104.8 0.1 6.7e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KPI42260.1 - 0.00037 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KPI42260.1 - 0.0074 16.8 0.1 0.018 15.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SUFU PF05076.13 KPI42260.1 - 0.068 13.2 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Suppressor of fused protein (SUFU) FTR1 PF03239.14 KPI42262.1 - 2.2e-82 276.7 8.0 3.9e-82 275.9 8.0 1.3 1 1 0 1 1 1 1 Iron permease FTR1 family MgtE PF01769.16 KPI42262.1 - 3.2 8.1 12.4 1.1 9.7 1.1 2.8 3 0 0 3 3 3 0 Divalent cation transporter NAD_kinase PF01513.21 KPI42263.1 - 8.8e-49 166.3 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KPI42263.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.22 KPI42264.1 - 4e-08 33.0 0.2 9.9e-06 25.1 0.0 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF4267 PF14087.6 KPI42265.1 - 2.5e-15 56.5 2.1 2.9e-15 56.3 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) VSP PF03302.13 KPI42266.1 - 0.073 11.9 3.5 0.1 11.4 3.5 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 KPI42266.1 - 2.5 8.2 14.3 21 5.1 14.3 2.2 1 1 0 1 1 1 0 Podoplanin Clr5 PF14420.6 KPI42267.1 - 2.8e-12 46.7 0.1 9.9e-12 44.9 0.1 1.9 2 0 0 2 2 1 1 Clr5 domain TPR_12 PF13424.6 KPI42267.1 - 1.9e-07 31.3 3.0 0.0024 18.1 0.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPI42267.1 - 8.1e-05 22.4 4.2 0.14 12.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KPI42267.1 - 0.00071 20.0 11.6 0.003 18.0 1.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPI42267.1 - 0.0039 17.7 2.9 0.091 13.3 0.6 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPI42267.1 - 0.0049 17.6 6.0 0.89 10.5 0.7 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPI42267.1 - 0.011 16.1 1.0 0.096 13.1 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI42267.1 - 0.017 15.7 1.1 0.19 12.4 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KPI42267.1 - 0.031 14.6 0.2 0.38 11.1 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KPI42267.1 - 0.038 14.6 1.5 0.038 14.6 1.5 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI42267.1 - 0.057 13.6 1.8 0.19 11.9 0.5 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KPI42267.1 - 0.19 11.8 1.0 26 5.1 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KPI42267.1 - 2.3 8.5 4.3 3.9 7.8 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyltransferase PF01553.21 KPI42268.1 - 5.2e-23 81.2 0.0 8.1e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KPI42268.1 - 3.6e-14 52.6 0.1 6.6e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus AA_permease PF00324.21 KPI42269.1 - 2.5e-143 478.2 38.5 3.1e-143 477.8 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI42269.1 - 8.1e-42 143.5 40.1 1.1e-41 143.1 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease LTV PF04180.14 KPI42270.1 - 3.3e-104 349.7 13.8 3.8e-104 349.5 13.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein TPR_21 PF09976.9 KPI42271.1 - 0.01 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain SLATT_1 PF18181.1 KPI42271.1 - 0.21 11.5 2.9 0.13 12.2 0.3 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 MFS_1 PF07690.16 KPI42272.1 - 3.5e-20 72.2 56.1 6.7e-17 61.4 43.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3H1 PF10650.9 KPI42273.1 - 6.8e-09 35.3 3.7 1.1e-08 34.6 3.7 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Cluap1 PF10234.9 KPI42273.1 - 0.0036 16.7 8.3 0.006 16.0 8.3 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 COG2 PF06148.11 KPI42273.1 - 2.8 8.0 10.2 1.9 8.6 5.9 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF724 PF05266.14 KPI42273.1 - 6.1 6.6 14.4 14 5.4 14.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FSH1 PF03959.13 KPI42274.1 - 2.7e-39 135.0 0.0 3.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Gpr1_Fun34_YaaH PF01184.19 KPI42275.1 - 2e-68 230.1 16.2 2.4e-68 229.8 16.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4064 PF13273.6 KPI42275.1 - 6.4 7.1 13.2 0.22 11.8 5.3 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF4064) ECH_1 PF00378.20 KPI42276.1 - 1.2e-32 113.2 0.0 1.5e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI42276.1 - 1.3e-13 51.2 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Methyltransf_31 PF13847.6 KPI42277.1 - 4.3e-14 52.6 0.0 6.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI42277.1 - 2.2e-13 50.7 0.1 5.7e-13 49.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI42277.1 - 8e-11 42.0 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI42277.1 - 1.3e-10 41.8 0.0 4.6e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI42277.1 - 1.9e-09 38.2 0.1 3.9e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI42277.1 - 1.9e-08 33.9 0.0 5.4e-07 29.2 0.0 2.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KPI42277.1 - 0.00058 19.6 0.0 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KPI42277.1 - 0.0024 17.9 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI42277.1 - 0.017 14.7 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 KPI42277.1 - 0.025 14.0 0.0 0.054 12.9 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF1772 PF08592.11 KPI42278.1 - 1.2e-26 93.6 0.0 2e-26 92.9 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) TB2_DP1_HVA22 PF03134.19 KPI42279.1 - 1.7e-21 75.9 2.5 2.5e-21 75.4 2.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MerC PF03203.14 KPI42279.1 - 0.14 12.6 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein WSC PF01822.19 KPI42280.1 - 4.2e-29 100.6 32.0 4.3e-16 58.9 11.7 2.6 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 KPI42280.1 - 4.3e-18 65.8 0.0 9.8e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 Peroxidase MAPEG PF01124.18 KPI42281.1 - 2.4e-13 50.1 0.7 4.2e-13 49.3 0.7 1.4 1 0 0 1 1 1 1 MAPEG family zinc_ribbon_10 PF10058.9 KPI42282.1 - 5.6e-21 74.0 0.1 9.7e-21 73.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein SMI1_KNR4 PF09346.10 KPI42283.1 - 4.4e-28 98.3 1.3 9.7e-28 97.2 0.1 2.1 2 1 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) AA_permease_2 PF13520.6 KPI42284.1 - 5.5e-18 65.0 23.0 6.2e-18 64.8 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI42284.1 - 3e-11 42.6 17.7 3.8e-11 42.3 17.7 1.1 1 0 0 1 1 1 1 Amino acid permease Ldh_2 PF02615.14 KPI42285.1 - 2.8e-84 283.1 0.1 3.2e-84 283.0 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-CCCH PF00642.24 KPI42286.1 - 1.8e-08 34.1 2.4 3.4e-08 33.2 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KPI42286.1 - 2.9e-08 33.4 5.3 5.5e-08 32.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI42286.1 - 8.3e-08 32.0 7.2 1.6e-07 31.1 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI42286.1 - 9e-08 32.0 5.4 1.8e-07 31.1 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI42286.1 - 1.7e-06 27.8 8.9 2.9e-06 27.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI42286.1 - 1.3e-05 25.1 8.1 2.2e-05 24.3 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KPI42286.1 - 2.5e-05 24.1 5.4 4.8e-05 23.3 5.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KPI42286.1 - 4.5e-05 23.5 3.3 4.5e-05 23.5 3.3 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KPI42286.1 - 8.6e-05 22.8 6.5 0.00016 21.9 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KPI42286.1 - 0.00073 19.3 5.9 0.0014 18.4 5.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 KPI42286.1 - 0.0011 18.7 1.9 0.0011 18.7 1.9 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KPI42286.1 - 0.011 15.9 7.7 0.025 14.7 7.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KPI42286.1 - 0.066 13.7 2.5 0.14 12.7 2.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger NADH_4Fe-4S PF10589.9 KPI42286.1 - 0.067 13.3 0.6 10 6.3 0.2 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Cript PF10235.9 KPI42286.1 - 0.069 13.7 2.6 0.13 12.8 1.1 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.7 KPI42286.1 - 0.16 12.2 3.2 0.34 11.2 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain GTP_CH_N PF12471.8 KPI42287.1 - 6.1e-90 300.2 0.0 8.7e-90 299.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KPI42287.1 - 1.6e-17 63.6 0.0 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II adh_short PF00106.25 KPI42288.1 - 1.7e-33 115.8 0.0 2.5e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42288.1 - 5e-19 68.8 0.0 7e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI42288.1 - 1.1e-06 28.7 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KPI42289.1 - 2.8e-48 164.5 5.4 8.1e-38 130.3 4.4 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42289.1 - 2.2e-46 157.8 3.9 3.2e-46 157.3 3.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42289.1 - 1.7e-16 60.7 3.4 2.2e-16 60.3 3.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI42289.1 - 0.00052 19.5 2.1 0.0013 18.3 1.9 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 KPI42289.1 - 0.0083 15.7 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4406 PF14359.6 KPI42289.1 - 0.016 15.7 0.1 0.031 14.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) Methyltransf_25 PF13649.6 KPI42289.1 - 0.038 14.7 0.1 0.081 13.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 KPI42289.1 - 0.056 12.8 0.5 0.087 12.2 0.5 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KPI42289.1 - 0.1 12.5 0.7 0.2 11.5 0.7 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Met_10 PF02475.16 KPI42289.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Vfa1 PF08432.10 KPI42290.1 - 1.1e-51 175.8 17.0 2.8e-38 132.1 11.1 2.0 2 0 0 2 2 2 2 AAA-ATPase Vps4-associated protein 1 Adeno_PV PF03910.13 KPI42290.1 - 0.039 12.7 6.3 0.065 11.9 6.3 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV RR_TM4-6 PF06459.12 KPI42290.1 - 0.2 11.5 6.4 4.4 7.1 6.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PIEZO PF15917.5 KPI42290.1 - 0.41 10.1 8.4 0.77 9.2 8.4 1.4 1 0 0 1 1 1 0 Piezo Sec62 PF03839.16 KPI42290.1 - 0.44 10.0 4.8 0.7 9.4 4.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 UBN_AB PF14075.6 KPI42290.1 - 0.74 9.5 10.0 2.1 8.0 9.7 1.8 2 0 0 2 2 2 0 Ubinuclein conserved middle domain RNA_pol_3_Rpc31 PF11705.8 KPI42290.1 - 0.99 9.6 14.6 1.7 8.9 14.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPL5 PF18168.1 KPI42290.1 - 1 8.6 5.9 1.6 8.0 5.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 KPI42290.1 - 2.8 6.1 7.9 2.7 6.2 6.9 1.4 2 0 0 2 2 2 0 CDC45-like protein PAPA-1 PF04795.12 KPI42290.1 - 3.4 8.5 19.1 0.17 12.7 13.5 1.7 2 0 0 2 2 2 0 PAPA-1-like conserved region CYSTM PF12734.7 KPI42291.1 - 8.1e-06 26.1 5.5 8.1e-06 26.1 5.5 5.2 3 2 0 3 3 3 1 Cysteine-rich TM module stress tolerance Fungal_trans_2 PF11951.8 KPI42293.1 - 3.7e-44 151.1 0.0 4.2e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI42293.1 - 2.6e-07 30.7 13.8 4.3e-07 29.9 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.21 KPI42294.1 - 1.8e-84 283.3 0.0 2.2e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPI42294.1 - 6e-05 23.0 0.1 0.0001 22.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans PF04082.18 KPI42295.1 - 3.6e-11 42.6 0.2 5.9e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI42295.1 - 6.6e-07 29.3 10.2 1.2e-06 28.5 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KPI42297.1 - 2.6e-94 316.2 17.9 2.6e-94 316.2 17.9 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KPI42297.1 - 7e-05 22.0 20.2 7e-05 22.0 20.2 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SH3_1 PF00018.28 KPI42298.1 - 4e-09 35.9 0.3 1.2e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KPI42298.1 - 1.4e-06 28.1 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI42298.1 - 1.9e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.14 KPI42298.1 - 0.046 13.3 9.0 0.071 12.7 9.0 1.2 1 0 0 1 1 1 0 YhhN family DUF2569 PF10754.9 KPI42298.1 - 2.7 8.4 10.6 5.4 7.5 10.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1129 PF06570.11 KPI42298.1 - 2.7 7.4 10.9 0.88 9.0 7.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Ras PF00071.22 KPI42299.1 - 2.5e-49 167.0 0.0 3e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI42299.1 - 8.8e-30 103.4 0.1 2.2e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI42299.1 - 3e-10 39.8 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPI42299.1 - 0.00033 20.7 0.0 0.00058 19.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KPI42299.1 - 0.00047 20.5 0.1 0.0025 18.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KPI42299.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KPI42299.1 - 0.024 14.1 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KPI42299.1 - 0.026 13.7 2.1 1.4 7.9 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KPI42299.1 - 0.034 14.1 0.1 9.2 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KPI42299.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KPI42299.1 - 0.062 13.0 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI42299.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KPI42299.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KPI42299.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KPI42299.1 - 0.19 11.0 0.5 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Septin GFA PF04828.14 KPI42300.1 - 8.6e-05 22.8 0.3 0.00016 22.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aminotran_4 PF01063.19 KPI42301.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Amino-transferase class IV Cu-oxidase_2 PF07731.14 KPI42302.1 - 3.7e-19 68.8 0.2 1.9e-18 66.5 0.2 2.1 1 1 0 1 1 1 1 Multicopper oxidase zf-RanBP PF00641.18 KPI42302.1 - 0.00015 21.0 0.4 0.00015 21.0 0.4 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Fungal_trans PF04082.18 KPI42303.1 - 0.11 11.5 1.2 0.61 9.1 0.5 2.2 2 1 0 2 2 2 0 Fungal specific transcription factor domain Allexi_40kDa PF05549.11 KPI42304.1 - 0.037 13.5 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein UME PF08064.13 KPI42304.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 UME (NUC010) domain ADH_zinc_N PF00107.26 KPI42305.1 - 5.8e-13 48.9 0.2 1.1e-12 48.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI42305.1 - 0.0024 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI42305.1 - 0.087 13.9 0.1 0.17 12.9 0.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ABC_membrane PF00664.23 KPI42307.1 - 5.6e-82 275.5 29.4 3.7e-46 158.0 8.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI42307.1 - 3.2e-65 218.8 0.0 2.3e-33 115.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI42307.1 - 7.3e-16 58.3 0.0 3.1e-05 23.5 0.1 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPI42307.1 - 1.7e-09 38.0 0.3 0.033 14.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KPI42307.1 - 5.9e-09 35.5 0.4 0.0018 17.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KPI42307.1 - 1.2e-06 29.0 6.7 0.0034 17.8 0.2 3.4 3 2 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPI42307.1 - 4.9e-06 26.6 0.0 0.028 14.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KPI42307.1 - 1.6e-05 24.7 0.4 0.027 14.2 0.0 3.3 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KPI42307.1 - 3.9e-05 23.0 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 KPI42307.1 - 0.0001 22.3 0.1 0.063 13.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 KPI42307.1 - 0.00025 21.5 0.0 0.77 10.2 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KPI42307.1 - 0.00028 21.0 0.0 0.43 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPI42307.1 - 0.00028 21.4 0.0 0.54 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KPI42307.1 - 0.00043 20.2 0.1 0.2 11.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPI42307.1 - 0.00044 20.8 0.1 0.45 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KPI42307.1 - 0.0011 18.8 0.0 1.4 8.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 KPI42307.1 - 0.0034 17.0 0.0 2 8.0 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DUF87 PF01935.17 KPI42307.1 - 0.0035 17.5 0.1 1 9.4 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KPI42307.1 - 0.0051 17.0 0.4 3.1 8.1 0.3 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KPI42307.1 - 0.0057 16.7 0.0 5.6 7.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KPI42307.1 - 0.0057 16.2 0.3 3.1 7.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KPI42307.1 - 0.011 14.6 0.0 0.54 9.0 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 KPI42307.1 - 0.015 15.4 0.0 4.2 7.5 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 KPI42307.1 - 0.018 14.7 0.0 0.93 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KPI42307.1 - 0.021 14.3 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3987 PF13148.6 KPI42307.1 - 0.031 13.3 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_17 PF13207.6 KPI42307.1 - 0.034 14.6 0.0 16 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KPI42307.1 - 0.075 12.9 0.1 16 5.3 0.0 2.8 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 KPI42307.1 - 0.095 12.4 0.1 11 5.7 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein PRK PF00485.18 KPI42307.1 - 0.17 11.6 0.1 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cad PF03596.13 KPI42307.1 - 1.1 9.2 7.2 1.5 8.7 2.3 2.4 2 0 0 2 2 2 0 Cadmium resistance transporter Zn_clus PF00172.18 KPI42308.1 - 4e-05 23.6 13.7 7e-05 22.9 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI42308.1 - 0.0091 15.1 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nsp1_C PF05064.13 KPI42308.1 - 0.038 13.8 0.7 0.099 12.5 0.4 1.9 1 1 0 1 1 1 0 Nsp1-like C-terminal region Dickkopf_N PF04706.12 KPI42308.1 - 0.21 12.1 9.4 0.54 10.8 9.4 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MMR_HSR1 PF01926.23 KPI42310.1 - 9.5e-17 61.1 0.3 4e-15 55.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI42310.1 - 4.5e-08 32.8 0.3 5.1e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KPI42310.1 - 6.7e-08 32.6 0.3 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KPI42310.1 - 0.011 15.4 1.2 0.031 13.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 KPI42310.1 - 0.014 14.8 0.1 0.014 14.8 0.1 2.1 2 1 0 2 2 2 0 AIG1 family MeaB PF03308.16 KPI42310.1 - 0.025 13.6 1.5 0.39 9.6 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KPI42310.1 - 0.16 12.0 0.1 0.16 12.0 0.1 3.1 3 0 0 3 3 3 0 Dynamin family APG6_N PF17675.1 KPI42310.1 - 1.6 9.3 12.0 3.7 8.1 12.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Glyco_transf_17 PF04724.13 KPI42312.1 - 7.4e-20 71.3 0.0 1.9e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 17 SnoaL_4 PF13577.6 KPI42313.1 - 3.6e-19 69.1 0.2 5e-19 68.7 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KPI42313.1 - 0.0078 16.8 0.3 0.019 15.6 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KPI42313.1 - 0.041 14.3 0.3 0.084 13.3 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SOG2 PF10428.9 KPI42314.1 - 0.0023 17.2 35.5 0.0023 17.2 35.5 2.3 2 0 0 2 2 2 2 RAM signalling pathway protein Cu_amine_oxid PF01179.20 KPI42315.1 - 2.9e-143 477.7 0.0 1.4e-140 468.9 0.0 2.2 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KPI42315.1 - 2.6e-09 37.2 0.0 5.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KPI42315.1 - 1.8e-07 31.5 0.0 4.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_63 PF03200.16 KPI42317.1 - 2.4e-169 564.2 1.0 2.4e-169 564.2 1.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KPI42317.1 - 1.2e-67 228.3 0.0 1.5e-66 224.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KPI42317.1 - 0.0097 14.8 0.5 0.0097 14.8 0.5 1.8 2 1 0 2 2 2 1 Trehalase RTC_insert PF05189.13 KPI42318.1 - 1.2e-26 93.2 0.0 2.4e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KPI42318.1 - 4.6e-25 88.1 0.0 5.7e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Pkinase PF00069.25 KPI42319.1 - 2.3e-51 174.7 0.0 3.2e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42319.1 - 8.8e-30 103.8 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI42319.1 - 2.6e-09 36.8 0.0 6.9e-08 32.1 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 KPI42319.1 - 0.015 14.7 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KPI42319.1 - 0.13 11.0 0.6 0.35 9.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Mg_trans_NIPA PF05653.14 KPI42320.1 - 8.1e-16 58.0 9.4 7.1e-08 31.9 1.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 KPI42320.1 - 4.4e-06 26.1 0.1 4.4e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KPI42320.1 - 2e-05 24.8 0.1 2e-05 24.8 0.1 3.2 3 0 0 3 3 3 1 EamA-like transporter family Neurensin PF14927.6 KPI42320.1 - 0.3 10.8 9.3 9.6 5.9 0.1 4.7 2 1 2 4 4 4 0 Neurensin Multi_Drug_Res PF00893.19 KPI42320.1 - 0.64 10.7 8.4 0.79 10.4 0.2 2.9 3 0 0 3 3 3 0 Small Multidrug Resistance protein HAD_2 PF13419.6 KPI42321.1 - 6.1e-07 29.7 0.0 2.4e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI42321.1 - 0.0042 17.4 0.0 3.3 7.9 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase SH3_1 PF00018.28 KPI42322.1 - 3.6e-10 39.3 0.1 6.6e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI42322.1 - 2.9e-08 33.5 0.2 5.3e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI42322.1 - 1.3e-07 31.2 0.0 2.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TPR_1 PF00515.28 KPI42323.1 - 5.6e-28 95.6 8.7 3e-06 26.8 0.1 10.3 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KPI42323.1 - 1.5e-23 80.9 22.3 0.0027 17.7 0.0 13.5 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 KPI42323.1 - 1.2e-14 54.5 21.5 0.00016 22.1 0.0 10.7 7 4 4 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KPI42323.1 - 6.1e-13 48.4 23.7 0.071 14.0 0.0 12.3 12 2 1 13 13 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPI42323.1 - 2e-12 47.5 10.8 0.064 13.9 0.0 9.2 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPI42323.1 - 5.6e-12 45.8 35.1 5.8e-05 23.3 1.7 10.4 11 1 2 13 13 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPI42323.1 - 4.6e-11 42.2 11.0 0.0019 17.8 0.3 7.8 8 0 0 8 8 8 3 TPR repeat TPR_8 PF13181.6 KPI42323.1 - 7.5e-10 38.2 22.8 0.0074 16.4 0.0 11.4 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI42323.1 - 1.8e-09 37.3 4.9 6.7 7.3 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPI42323.1 - 8.2e-08 32.4 25.7 0.041 14.5 0.0 11.2 13 0 0 13 13 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI42323.1 - 0.0016 18.6 15.2 0.19 11.9 0.2 5.9 6 1 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KPI42323.1 - 0.0052 16.9 9.2 5.2 7.3 0.0 6.2 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 KPI42323.1 - 0.0097 15.9 3.8 0.17 11.9 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPI42323.1 - 0.016 15.2 22.2 0.043 13.9 0.0 9.6 12 0 0 12 12 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KPI42323.1 - 0.035 14.2 7.5 52 4.0 0.0 6.6 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat Vta1_C PF18097.1 KPI42323.1 - 0.082 12.6 5.5 9.6 6.0 0.0 4.4 5 0 0 5 5 5 0 Vta1 C-terminal domain EF1_GNE PF00736.19 KPI42324.1 - 6.9e-32 109.5 3.9 1.5e-31 108.4 3.9 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KPI42324.1 - 1.7e-11 44.4 2.7 1.7e-11 44.4 2.7 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KPI42324.1 - 0.015 15.5 1.8 0.028 14.7 0.1 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI42324.1 - 0.029 14.6 0.3 0.08 13.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Mcp5_PH PF12814.7 KPI42325.1 - 1.8e-45 154.0 0.1 3.2e-45 153.2 0.1 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KPI42325.1 - 7.8e-05 23.1 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 PH domain SHE3 PF17078.5 KPI42325.1 - 0.00022 21.0 5.9 0.00022 21.0 5.9 3.1 3 1 0 3 3 3 1 SWI5-dependent HO expression protein 3 TPR_MLP1_2 PF07926.12 KPI42325.1 - 0.0076 16.3 19.3 0.0076 16.3 19.3 4.7 4 1 0 4 4 4 2 TPR/MLP1/MLP2-like protein DUF2457 PF10446.9 KPI42326.1 - 1 8.5 8.5 1.4 7.9 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SGL PF08450.12 KPI42327.1 - 0.00098 18.8 0.2 1.1 8.8 0.0 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region P2_N PF18628.1 KPI42327.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain ABC_tran_CTD PF16326.5 KPI42328.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain TSP9 PF11493.8 KPI42328.1 - 0.1 13.3 1.1 0.37 11.5 1.1 2.0 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 vATP-synt_E PF01991.18 KPI42329.1 - 1.1e-60 204.4 9.6 1.3e-60 204.2 9.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3435 PF11917.8 KPI42329.1 - 0.031 13.2 2.9 0.053 12.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Myb_DNA-bind_6 PF13921.6 KPI42330.1 - 0.0053 17.0 0.3 0.0089 16.3 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3176 PF11374.8 KPI42331.1 - 0.17 12.1 1.3 0.36 11.1 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) DUF3589 PF12141.8 KPI42333.1 - 6.4e-67 226.2 0.0 1.6e-64 218.3 0.0 2.3 1 1 0 1 1 1 1 Beta-mannosyltransferases DUF3425 PF11905.8 KPI42333.1 - 4.4e-10 39.6 0.0 8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RRM_1 PF00076.22 KPI42334.1 - 7.2e-19 67.4 0.0 1.1e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KPI42334.1 - 1.3e-05 25.7 13.2 1.3e-05 25.7 13.2 4.6 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Pyr_redox_2 PF07992.14 KPI42336.1 - 5.8e-21 75.0 0.2 4.2e-17 62.3 0.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI42336.1 - 2.2e-11 44.2 0.1 3.4e-09 37.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI42336.1 - 0.00042 19.7 0.3 0.0023 17.2 0.0 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI42336.1 - 0.0035 16.5 0.1 0.91 8.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KPI42336.1 - 0.0044 15.9 0.2 1.6 7.4 0.2 2.6 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 KPI42336.1 - 0.0052 16.4 0.9 0.028 14.0 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KPI42336.1 - 0.043 12.9 0.3 0.77 8.8 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KPI42336.1 - 0.087 12.1 1.0 24 4.0 0.1 3.0 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 KPI42336.1 - 0.19 10.8 0.2 0.33 10.0 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SNF2_N PF00176.23 KPI42337.1 - 7.3e-64 215.7 2.5 7.3e-64 215.7 2.5 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KPI42337.1 - 4.1e-47 159.9 24.0 4.1e-47 159.9 24.0 4.9 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KPI42337.1 - 2.5e-19 69.7 0.0 6e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI42337.1 - 1.4e-05 25.2 0.5 6.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 KPI42337.1 - 0.02 14.5 1.3 0.062 13.0 1.3 1.8 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain CBP_BcsQ PF06564.12 KPI42337.1 - 0.077 12.5 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ DAO PF01266.24 KPI42338.1 - 2.9e-65 221.2 1.6 3.4e-65 221.0 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI42338.1 - 6.2e-06 25.6 0.1 0.062 12.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI42338.1 - 0.00051 20.2 0.9 0.00051 20.2 0.9 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KPI42338.1 - 0.058 12.2 0.1 0.084 11.7 0.1 1.2 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 KPI42338.1 - 0.085 12.8 0.7 0.54 10.2 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KPI42338.1 - 0.086 11.9 1.9 0.43 9.6 1.9 1.9 1 1 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KPI42338.1 - 0.14 12.4 0.5 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 KPI42338.1 - 0.17 10.7 0.7 0.27 10.0 0.7 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lipase_3 PF01764.25 KPI42339.1 - 0.047 13.5 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 KPI42339.1 - 0.11 13.1 0.0 0.48 11.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ECH_1 PF00378.20 KPI42340.1 - 6.1e-12 45.4 0.0 2e-09 37.2 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 KPI42341.1 - 5.1e-32 110.9 0.0 6.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42341.1 - 7.3e-28 97.7 0.0 1.2e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI42341.1 - 0.0016 18.4 0.0 0.095 12.6 0.0 2.2 2 0 0 2 2 2 1 KR domain UCR_TM PF02921.14 KPI42341.1 - 0.16 12.5 0.5 0.33 11.4 0.5 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Aminotran_5 PF00266.19 KPI42342.1 - 2.8e-26 92.4 0.0 5.8e-18 65.0 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class-V TYW3 PF02676.14 KPI42343.1 - 4.2e-62 209.3 0.0 7.7e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF5448 PF17526.2 KPI42343.1 - 0.086 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Pyridox_oxase_2 PF12766.7 KPI42344.1 - 1.4e-18 67.3 0.0 3.9e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase T2SSI PF02501.17 KPI42344.1 - 0.56 10.4 2.9 1.4 9.1 0.4 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Bax1-I PF01027.20 KPI42345.1 - 2.3e-38 132.1 26.2 3.3e-31 108.8 20.0 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 SfLAP PF11139.8 KPI42345.1 - 0.012 15.1 0.2 0.012 15.1 0.2 2.4 2 1 0 2 2 2 0 Sap, sulfolipid-1-addressing protein TRAPP PF04051.16 KPI42346.1 - 2.8e-23 82.2 0.0 3.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FUN14 PF04930.15 KPI42347.1 - 9.7e-09 35.5 1.3 4.1e-08 33.5 1.6 1.8 2 0 0 2 2 2 1 FUN14 family Dynactin_p22 PF07426.11 KPI42349.1 - 0.0016 18.3 0.1 0.007 16.2 0.0 1.9 2 0 0 2 2 2 1 Dynactin subunit p22 Med9 PF07544.13 KPI42349.1 - 0.035 14.2 0.1 0.51 10.5 0.2 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4239 PF14023.6 KPI42349.1 - 0.055 13.2 0.2 0.087 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TraC PF07820.12 KPI42349.1 - 0.07 13.5 0.8 0.76 10.1 0.1 2.5 2 0 0 2 2 2 0 TraC-like protein HALZ PF02183.18 KPI42349.1 - 0.088 13.0 0.6 0.3 11.3 0.1 2.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 KPI42349.1 - 0.1 11.5 0.3 0.15 10.9 0.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KPI42349.1 - 0.1 12.6 1.1 0.32 11.0 1.1 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 KPI42349.1 - 4.1 7.9 6.8 1.3 9.5 2.8 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spt4 PF06093.13 KPI42350.1 - 1.1e-28 99.2 0.0 1.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger FAD_binding_3 PF01494.19 KPI42351.1 - 1.2e-43 149.7 0.0 1.7e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI42351.1 - 3e-06 27.1 0.0 0.02 14.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI42351.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI42351.1 - 0.00017 21.0 0.1 0.0087 15.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI42351.1 - 0.00038 19.9 0.4 0.0033 16.9 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI42351.1 - 0.00053 20.2 0.1 0.0016 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI42351.1 - 0.00058 19.0 0.2 0.034 13.2 0.2 2.1 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI42351.1 - 0.0013 17.5 0.2 0.0051 15.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KPI42351.1 - 0.004 16.4 0.1 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KPI42351.1 - 0.0053 16.1 1.0 0.072 12.4 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KPI42351.1 - 0.0091 15.1 0.5 0.025 13.6 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KPI42351.1 - 0.014 15.9 0.1 7.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI42351.1 - 0.028 14.4 0.4 0.76 9.8 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KPI42351.1 - 0.13 11.1 0.3 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase MIF4G_like PF09088.11 KPI42352.1 - 1.8e-77 259.4 0.2 3.4e-77 258.5 0.2 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KPI42352.1 - 2.8e-47 161.4 0.0 4.4e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KPI42352.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain TSP9 PF11493.8 KPI42352.1 - 0.18 12.5 0.0 0.61 10.8 0.0 1.9 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 zf-RING_2 PF13639.6 KPI42353.1 - 2.9e-11 43.5 5.6 4.6e-11 42.9 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KPI42353.1 - 8.7e-07 29.1 3.6 1.8e-06 28.1 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KPI42353.1 - 1.4e-06 27.9 3.1 2.6e-06 27.1 3.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KPI42353.1 - 8e-06 25.6 5.4 1.4e-05 24.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI42353.1 - 5.7e-05 22.9 2.9 9.6e-05 22.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI42353.1 - 0.00018 21.3 4.8 0.0003 20.6 4.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KPI42353.1 - 0.00076 19.4 2.4 0.0012 18.7 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KPI42353.1 - 0.0042 17.1 1.5 0.0085 16.1 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KPI42353.1 - 0.01 15.7 1.7 0.017 15.0 1.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KPI42353.1 - 0.4 10.4 2.8 0.73 9.5 2.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.6 KPI42353.1 - 0.51 10.4 6.6 1 9.5 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger CMAS PF02353.20 KPI42355.1 - 1.2e-59 201.9 0.0 1.4e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KPI42355.1 - 1.4e-10 41.6 0.0 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI42355.1 - 3.2e-09 37.4 0.0 3.5e-08 34.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI42355.1 - 7.9e-09 35.6 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI42355.1 - 0.0079 16.9 0.0 0.025 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KPI42355.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KPI42355.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KPI42355.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.16 KPI42356.1 - 1.3e-25 90.1 23.1 1e-22 80.5 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAC PF01849.18 KPI42357.1 - 2.6e-23 81.7 0.2 2.6e-23 81.7 0.2 1.7 2 0 0 2 2 2 1 NAC domain Geminin PF07412.12 KPI42357.1 - 0.0095 15.7 1.4 0.014 15.1 1.4 1.3 1 0 0 1 1 1 1 Geminin DUF601 PF04642.12 KPI42358.1 - 0.67 9.4 4.1 1.1 8.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 PLDc_2 PF13091.6 KPI42359.1 - 2.6e-14 53.3 0.0 1.2e-06 28.5 0.0 2.6 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KPI42359.1 - 6.8e-07 29.2 1.5 0.04 14.1 0.1 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif Virulence_RhuM PF13310.6 KPI42359.1 - 0.053 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Virulence protein RhuM family Abhydrolase_1 PF00561.20 KPI42360.1 - 2e-47 162.0 0.0 6.6e-47 160.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KPI42360.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Solute_trans_a PF03619.16 KPI42361.1 - 4.8e-69 232.8 20.6 5.7e-69 232.6 20.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Brr6_like_C_C PF10104.9 KPI42361.1 - 0.93 9.3 7.2 0.77 9.5 0.3 2.6 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Usp PF00582.26 KPI42362.1 - 2e-09 38.1 2.9 8.9e-06 26.3 0.0 3.1 3 0 0 3 3 3 2 Universal stress protein family Pkinase PF00069.25 KPI42363.1 - 6.6e-66 222.4 0.0 2.1e-36 125.7 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42363.1 - 1.4e-34 119.6 0.0 1.9e-16 60.1 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KPI42363.1 - 1.2e-12 48.2 0.2 1.2e-12 48.2 0.2 2.4 2 0 0 2 2 2 1 RWD domain HGTP_anticodon2 PF12745.7 KPI42363.1 - 3.9e-12 46.2 0.0 3.9e-12 46.2 0.0 2.8 3 1 0 3 3 3 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 KPI42363.1 - 1.9e-09 37.2 0.0 1.9e-09 37.2 0.0 2.5 3 0 0 3 3 3 1 Histidyl-tRNA synthetase FTA2 PF13095.6 KPI42363.1 - 0.0054 16.4 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KPI42363.1 - 0.011 15.6 3.6 0.057 13.3 0.0 3.4 4 0 0 4 4 4 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KPI42364.1 - 6.2e-94 315.4 17.2 6.2e-94 315.4 17.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42364.1 - 6e-26 91.2 37.4 1e-21 77.3 6.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KPI42365.1 - 5.4e-08 32.5 0.0 9e-05 21.9 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI42365.1 - 3.3e-05 23.6 0.3 0.061 12.9 0.5 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI42365.1 - 0.011 15.9 0.1 0.04 14.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI42365.1 - 0.028 13.7 0.7 0.64 9.2 0.9 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI42365.1 - 0.15 11.1 1.4 0.25 10.4 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain MIP PF00230.20 KPI42366.1 - 2e-54 184.7 2.2 2.6e-54 184.4 2.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MCM PF00493.23 KPI42367.1 - 2.6e-103 343.9 0.1 3.9e-103 343.4 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPI42367.1 - 1.9e-37 127.9 0.8 3.7e-37 127.0 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KPI42367.1 - 1.7e-29 102.2 0.1 4.1e-29 101.0 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KPI42367.1 - 5.3e-23 81.2 0.0 1.5e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KPI42367.1 - 5.9e-22 78.2 0.4 2.5e-21 76.2 0.4 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KPI42367.1 - 3.8e-07 29.7 0.0 1.3e-05 24.7 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPI42367.1 - 0.0015 18.6 0.0 0.0052 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KPI42367.1 - 0.0033 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KPI42367.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T5orf172 PF10544.9 KPI42369.1 - 5e-22 78.4 0.1 1.2e-21 77.1 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KPI42369.1 - 5.6e-22 78.2 0.0 1.2e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 RRM_1 PF00076.22 KPI42371.1 - 7.3e-16 57.8 0.0 1.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI42371.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 KPI42371.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 KPI42372.1 - 1.4e-48 165.8 63.4 6.4e-48 163.6 63.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI42372.1 - 1.1e-22 80.3 44.7 1.1e-22 80.3 44.7 1.6 1 1 1 2 2 2 1 Amino acid permease Phage_CII PF05269.11 KPI42372.1 - 0.0067 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage CII protein CAF1 PF04857.20 KPI42374.1 - 1e-26 93.9 0.2 4.2e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease Patatin PF01734.22 KPI42375.1 - 8e-23 81.7 0.0 4.4e-22 79.3 0.0 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase Sugar_tr PF00083.24 KPI42377.1 - 1e-107 360.9 29.6 1.5e-107 360.3 29.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42377.1 - 1.3e-25 90.1 34.6 1.3e-25 90.1 34.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KPI42377.1 - 0.38 9.2 30.6 0.12 10.9 12.6 3.6 3 1 0 3 3 3 0 MFS/sugar transport protein Tom6 PF17112.5 KPI42377.1 - 0.46 10.0 2.0 0.54 9.8 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal Dicty_REP PF05086.12 KPI42378.1 - 0.048 11.6 4.8 0.041 11.9 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KPI42378.1 - 0.084 12.8 11.0 0.14 12.1 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 KPI42378.1 - 0.16 10.1 10.9 0.17 10.1 10.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA PF00004.29 KPI42380.1 - 1.7e-46 157.9 0.0 1.3e-40 138.9 0.0 3.4 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI42380.1 - 2.9e-12 47.3 0.1 0.00016 22.1 0.2 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KPI42380.1 - 1.2e-11 44.2 3.9 9.1e-08 31.8 0.0 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_5 PF07728.14 KPI42380.1 - 1.6e-07 31.4 0.3 0.00086 19.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI42380.1 - 5.6e-06 26.7 0.0 0.22 11.8 0.0 3.8 4 1 1 5 5 4 2 AAA domain Rad17 PF03215.15 KPI42380.1 - 1.6e-05 24.9 0.0 0.014 15.3 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KPI42380.1 - 4.2e-05 23.9 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 KPI42380.1 - 0.00035 19.8 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 KPI42380.1 - 0.0004 20.7 0.0 1.3 9.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KPI42380.1 - 0.00045 19.8 0.2 1 8.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KPI42380.1 - 0.00066 19.5 0.0 0.014 15.1 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KPI42380.1 - 0.0014 18.6 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 KPI42380.1 - 0.0027 17.7 0.2 1.6 8.8 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 KPI42380.1 - 0.0053 16.3 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 KPI42380.1 - 0.0078 15.5 0.1 0.019 14.2 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 KPI42380.1 - 0.009 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KPI42380.1 - 0.022 14.9 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KPI42380.1 - 0.025 14.0 0.4 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KPI42380.1 - 0.036 14.0 0.4 18 5.2 0.0 3.6 2 2 1 3 3 3 0 NACHT domain TsaE PF02367.17 KPI42380.1 - 0.038 14.0 0.0 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KPI42380.1 - 0.044 13.5 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain CDC48_N PF02359.18 KPI42380.1 - 0.051 13.8 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.11 KPI42380.1 - 0.052 13.4 0.0 0.43 10.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KPI42380.1 - 0.065 13.0 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPI42380.1 - 0.072 13.6 0.0 20 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KPI42380.1 - 0.21 11.5 0.0 32 4.3 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Cutinase PF01083.22 KPI42381.1 - 6.1e-39 133.8 0.5 7.2e-39 133.6 0.5 1.1 1 0 0 1 1 1 1 Cutinase Fungal_trans PF04082.18 KPI42382.1 - 2.5e-13 49.7 0.7 4.1e-13 49.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleo_P87 PF07267.11 KPI42382.1 - 0.21 10.4 0.3 0.26 10.1 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MAGE_N PF12440.8 KPI42382.1 - 1.6 9.5 7.1 1.9 9.2 4.9 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal dCMP_cyt_deam_1 PF00383.23 KPI42383.1 - 1.7e-25 88.8 0.0 2.2e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPI42383.1 - 2.5e-21 75.9 0.0 3.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KPI42383.1 - 0.0005 20.2 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KPI42383.1 - 0.005 16.9 1.5 0.18 11.9 0.1 2.2 1 1 0 2 2 2 1 Bd3614-like deaminase NAD2 PF18782.1 KPI42383.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 KPI42383.1 - 0.029 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KPI42383.1 - 0.041 14.0 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 KPI42383.1 - 0.08 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC_N PF08210.11 KPI42383.1 - 0.2 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Solute_trans_a PF03619.16 KPI42384.1 - 1e-87 294.0 21.3 1.2e-87 293.8 21.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TssN PF17555.2 KPI42384.1 - 1.6 8.0 16.4 0.91 8.9 1.6 2.9 2 1 1 3 3 3 0 Type VI secretion system, TssN Brr6_like_C_C PF10104.9 KPI42384.1 - 9.1 6.1 11.4 1.2 8.9 1.4 2.9 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain 5_nucleotid_C PF02872.18 KPI42386.1 - 2.1e-37 128.8 0.2 9.2e-37 126.7 0.0 2.0 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KPI42386.1 - 5.1e-10 40.2 0.4 1.6e-09 38.6 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KPI42386.1 - 0.029 13.7 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 YmdB-like protein FAD_binding_3 PF01494.19 KPI42387.1 - 3.7e-78 263.2 0.0 4.6e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPI42387.1 - 1.3e-46 158.6 0.0 2.5e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 KPI42387.1 - 4.2e-06 26.6 1.7 8.9e-05 22.2 1.6 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI42387.1 - 0.0027 16.9 1.5 0.071 12.2 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI42387.1 - 0.012 14.9 0.5 0.23 10.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI42387.1 - 0.015 14.6 0.1 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KPI42387.1 - 0.074 13.3 0.4 0.44 10.8 0.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_C33 PF05412.12 KPI42387.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase SE PF08491.10 KPI42387.1 - 0.15 11.0 0.1 6.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 KPI42387.1 - 0.33 10.0 1.0 1.6 7.8 1.0 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.22 KPI42388.1 - 4.7e-49 167.4 0.0 7e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MspA PF09203.11 KPI42388.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 MspA DUF1996 PF09362.10 KPI42389.1 - 6.1e-71 239.1 1.8 1.1e-70 238.3 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KPI42389.1 - 6.5e-52 173.7 54.4 1.6e-14 53.9 13.0 4.7 4 0 0 4 4 4 4 WSC domain TAP_C PF03943.13 KPI42389.1 - 0.025 14.2 8.3 0.049 13.3 1.4 3.5 3 0 0 3 3 3 0 TAP C-terminal domain Hydrolase_4 PF12146.8 KPI42391.1 - 2.4e-09 36.8 0.0 1.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI42391.1 - 7.9e-09 36.4 0.5 1.2e-08 35.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI42391.1 - 4.1e-07 29.7 0.0 0.009 15.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KPI42391.1 - 1.2e-06 28.6 0.3 2.7e-06 27.4 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KPI42391.1 - 0.00016 21.3 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.13 KPI42391.1 - 0.00052 19.8 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 KPI42391.1 - 0.0015 18.5 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KPI42391.1 - 0.05 12.3 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 KPI42391.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain PLA2_B PF01735.18 KPI42392.1 - 3e-99 332.7 0.1 3.7e-99 332.4 0.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Urocanase_N PF17391.2 KPI42392.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Urocanase N-terminal domain Erf4 PF10256.9 KPI42393.1 - 2.6e-38 130.7 0.0 3.4e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Sugar_tr PF00083.24 KPI42394.1 - 7.2e-91 305.3 29.4 8.1e-91 305.1 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42394.1 - 1.7e-19 70.0 31.0 1.7e-19 70.0 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 KPI42394.1 - 0.13 12.0 1.2 0.31 10.7 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) OATP PF03137.20 KPI42394.1 - 4.2 5.5 18.9 0.04 12.2 4.1 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF5337 PF17272.2 KPI42394.1 - 8.9 6.2 6.5 2.2 8.2 1.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) zf-C2H2 PF00096.26 KPI42395.1 - 0.092 13.2 0.8 0.092 13.2 0.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KPI42395.1 - 0.095 13.0 2.3 0.95 9.8 0.3 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KPI42395.1 - 2.9 9.0 13.7 0.86 10.6 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI42395.1 - 7.3 7.0 9.0 0.34 11.2 2.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 KPI42396.1 - 4.4e-65 219.7 0.0 5.2e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42396.1 - 9.2e-25 87.4 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI42396.1 - 2.8e-06 26.9 0.0 1.4e-05 24.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KPI42396.1 - 0.0011 18.9 0.2 0.0088 16.0 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KPI42396.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec63 PF02889.16 KPI42397.1 - 1.3e-157 522.6 1.7 3.4e-91 305.0 0.0 2.5 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 KPI42397.1 - 1.8e-50 171.1 0.0 1e-26 93.8 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KPI42397.1 - 9.5e-30 103.0 2.3 3.2e-29 101.4 2.3 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KPI42397.1 - 1.9e-26 93.1 0.0 2.1e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI42397.1 - 4.4e-12 46.3 0.0 5.9e-08 33.0 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KPI42397.1 - 2.4e-07 31.1 0.1 0.0011 19.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 KPI42397.1 - 0.001 18.5 0.0 0.083 12.3 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KPI42397.1 - 0.016 14.3 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FANCI_S1-cap PF14674.6 KPI42397.1 - 6.5 6.9 6.4 13 5.9 0.0 4.2 4 0 0 4 4 4 0 FANCI solenoid 1 cap Spo12 PF05032.12 KPI42398.1 - 1.2e-08 34.7 1.1 1.2e-08 34.7 1.1 1.8 2 0 0 2 2 2 1 Spo12 family DFRP_C PF16543.5 KPI42398.1 - 0.11 13.0 1.0 0.14 12.7 0.3 1.5 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 MDFI PF15316.6 KPI42398.1 - 3.9 7.5 7.1 6.1 6.9 7.1 1.4 1 1 0 1 1 1 0 MyoD family inhibitor DUF2263 PF10021.9 KPI42399.1 - 3.3e-19 69.7 0.0 1.6e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KPI42399.1 - 0.00044 20.3 0.0 0.00077 19.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain DUF2015 PF09435.10 KPI42401.1 - 7.6e-42 141.7 0.0 9.1e-42 141.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Rep_fac_C PF08542.11 KPI42402.1 - 1.2e-23 83.3 0.1 3.6e-23 81.8 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KPI42402.1 - 1.2e-11 44.6 0.0 3.3e-08 33.5 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KPI42402.1 - 1.7e-10 41.4 0.1 3e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KPI42402.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI42402.1 - 1.2e-05 25.7 0.0 0.00054 20.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KPI42402.1 - 1.9e-05 24.5 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KPI42402.1 - 9.8e-05 22.2 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPI42402.1 - 0.00012 22.3 0.1 0.28 11.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 KPI42402.1 - 0.00019 21.3 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KPI42402.1 - 0.00082 19.2 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KPI42402.1 - 0.0016 17.9 0.0 0.014 14.8 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KPI42402.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 KPI42402.1 - 0.0041 16.9 0.0 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KPI42402.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 KPI42402.1 - 0.0098 15.3 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_19 PF13245.6 KPI42402.1 - 0.012 15.9 0.3 0.033 14.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KPI42402.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_11 PF13086.6 KPI42402.1 - 0.026 14.3 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPI42402.1 - 0.029 14.3 0.3 0.082 12.8 0.2 1.8 1 1 0 2 2 2 0 NTPase KTI12 PF08433.10 KPI42402.1 - 0.053 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DNA_pol3_gamma3 PF12169.8 KPI42402.1 - 0.062 13.2 0.6 4.4 7.2 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_30 PF13604.6 KPI42402.1 - 0.068 12.9 0.4 0.22 11.2 0.3 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KPI42402.1 - 0.081 12.7 0.2 1.2 8.9 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase MipZ PF09140.11 KPI42402.1 - 0.1 11.9 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_5 PF07728.14 KPI42402.1 - 0.12 12.4 0.0 0.46 10.5 0.0 2.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KPI42402.1 - 0.13 11.8 0.1 0.91 9.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain RRM_1 PF00076.22 KPI42405.1 - 1.1e-13 50.8 0.0 1.6e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPI42405.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI42405.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif GFO_IDH_MocA PF01408.22 KPI42406.1 - 1.7e-18 67.6 0.0 5.7e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KPI42406.1 - 8.1e-06 25.8 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KPI42406.1 - 0.005 17.5 0.0 0.0099 16.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PPR_2 PF13041.6 KPI42407.1 - 8.8e-09 35.4 0.0 0.009 16.2 0.0 4.5 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 KPI42407.1 - 2.9e-07 30.3 0.0 0.017 15.4 0.0 5.0 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 KPI42407.1 - 0.017 15.2 0.0 0.87 9.7 0.0 3.3 3 1 1 4 4 4 0 Pentatricopeptide repeat domain PRO8NT PF08082.11 KPI42407.1 - 0.017 15.0 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain T3SS_needle_E PF08988.10 KPI42407.1 - 1.2 9.3 7.7 0.15 12.2 0.3 2.9 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Helo_like_N PF17111.5 KPI42408.1 - 1.8e-09 37.3 0.6 3.1e-09 36.5 0.6 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins YabA PF06156.13 KPI42408.1 - 0.021 15.4 0.5 0.82 10.3 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Cluap1 PF10234.9 KPI42408.1 - 0.11 11.9 0.2 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 Cep57_CLD_2 PF14197.6 KPI42408.1 - 0.2 11.8 1.2 7.2 6.8 0.2 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 KPI42408.1 - 0.26 11.3 2.9 0.97 9.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IDO PF01231.18 KPI42409.1 - 7e-91 305.2 0.0 8.8e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KPI42409.1 - 0.077 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) MFS_1 PF07690.16 KPI42410.1 - 3.6e-38 131.4 11.9 3.6e-38 131.4 11.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI42410.1 - 1.1e-14 54.2 5.0 1.1e-12 47.6 0.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KPI42410.1 - 4.8e-08 32.3 0.3 4.8e-08 32.3 0.3 2.5 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 KPI42410.1 - 0.0012 18.3 1.1 0.0012 18.3 1.1 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KPI42410.1 - 0.0015 17.2 1.6 0.0015 17.2 1.6 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein FAA_hydrolase PF01557.18 KPI42411.1 - 5.7e-54 183.1 0.0 7.8e-53 179.4 0.0 2.0 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S8 PF00082.22 KPI42412.1 - 9e-17 61.3 0.0 1.8e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Subtilase family HIGH_NTase1 PF05636.11 KPI42412.1 - 0.091 11.9 1.8 0.14 11.4 1.8 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase FAA_hydrolase PF01557.18 KPI42413.1 - 8.5e-64 215.2 0.0 1.3e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 KPI42413.1 - 1.6e-20 73.8 0.1 3.6e-17 62.8 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42413.1 - 5e-19 69.8 0.7 7.1e-19 69.3 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI42413.1 - 2e-15 56.7 0.0 4.7e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KPI42413.1 - 4.1e-05 23.5 0.5 0.00014 21.8 0.3 1.8 1 1 1 2 2 2 1 Serine hydrolase Thioesterase PF00975.20 KPI42413.1 - 0.00091 19.4 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KPI42413.1 - 0.0016 17.2 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Poly_export PF02563.16 KPI42413.1 - 0.035 14.3 0.1 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein SpoVS PF04232.12 KPI42413.1 - 0.081 12.7 2.0 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 Stage V sporulation protein S (SpoVS) Esterase PF00756.20 KPI42413.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_8 PF06259.12 KPI42413.1 - 0.16 11.6 2.8 0.43 10.2 0.5 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase Glyco_hydro_127 PF07944.12 KPI42414.1 - 8.2e-104 347.9 0.0 9.5e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Epimerase PF01370.21 KPI42415.1 - 1.5e-23 83.6 0.0 2.7e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI42415.1 - 8.3e-14 51.7 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI42415.1 - 5.5e-08 32.2 0.0 1.4e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPI42415.1 - 5.1e-07 29.1 0.0 7.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KPI42415.1 - 2.6e-06 26.8 0.0 1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KPI42415.1 - 4.6e-06 26.2 0.2 3.5e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KPI42415.1 - 8e-05 21.9 0.1 0.00014 21.1 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KPI42415.1 - 0.00018 21.4 0.6 0.0004 20.3 0.1 1.8 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPI42415.1 - 0.0036 16.9 0.1 0.061 12.9 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family Hydrolase_4 PF12146.8 KPI42417.1 - 2.1e-25 89.4 0.3 1.5e-24 86.6 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI42417.1 - 3.2e-24 86.0 0.1 4.7e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42417.1 - 3.9e-17 63.6 0.1 4.9e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI42417.1 - 9.1e-08 31.8 0.0 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KPI42417.1 - 0.0002 21.1 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 KPI42417.1 - 0.0002 21.1 0.0 0.12 12.1 0.0 2.4 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KPI42417.1 - 0.00023 21.0 0.0 0.00097 19.0 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 KPI42417.1 - 0.0034 17.0 0.0 0.023 14.3 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family LIP PF03583.14 KPI42417.1 - 0.016 14.6 0.0 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Ser_hydrolase PF06821.13 KPI42417.1 - 0.039 13.8 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.7 KPI42417.1 - 0.051 12.5 0.0 0.16 10.9 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.13 KPI42417.1 - 0.053 13.2 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ndr PF03096.14 KPI42417.1 - 0.059 12.1 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.11 KPI42417.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.13 KPI42417.1 - 0.13 10.8 0.0 8.8 4.7 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_4 PF08386.10 KPI42417.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein BAAT_C PF08840.11 KPI42417.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal bZIP_1 PF00170.21 KPI42419.1 - 0.00015 21.7 0.6 0.0004 20.4 0.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 KPI42419.1 - 0.067 13.0 0.8 0.54 10.1 0.1 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain YkyA PF10368.9 KPI42419.1 - 0.12 12.1 0.4 0.25 11.0 0.4 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein bZIP_Maf PF03131.17 KPI42419.1 - 3.2 8.3 6.5 0.36 11.4 1.6 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Sad1_UNC PF07738.13 KPI42420.1 - 1.5e-30 105.9 0.0 3.3e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MFS_1 PF07690.16 KPI42421.1 - 4.2e-28 98.3 19.9 4.2e-28 98.3 19.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 KPI42421.1 - 0.021 13.5 12.4 0.071 11.7 0.6 2.9 2 2 1 3 3 3 0 Vacuole effluxer Atg22 like Kin17_mid PF10357.9 KPI42422.1 - 4.7e-51 172.0 1.9 7.9e-51 171.2 1.9 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KPI42422.1 - 0.00029 21.0 0.9 0.00057 20.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI42422.1 - 0.0011 19.3 2.2 0.0022 18.3 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KPI42422.1 - 0.021 15.2 5.2 0.022 15.1 0.4 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) GP4 PF03010.14 KPI42422.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 GP4 DUF4666 PF15697.5 KPI42422.1 - 1.9 9.2 6.0 0.73 10.5 2.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4666) RRM_1 PF00076.22 KPI42423.1 - 3.6e-33 113.2 0.0 3.3e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPI42423.1 - 0.00015 21.3 0.0 0.012 15.2 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI42423.1 - 0.004 17.3 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KPI42423.1 - 0.047 13.4 0.2 9.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_occluded PF16842.5 KPI42423.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KPI42423.1 - 0.18 11.9 0.0 24 5.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Aconitase PF00330.20 KPI42424.1 - 1.1e-112 377.4 0.3 1.1e-111 374.1 0.3 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPI42424.1 - 2.3e-25 89.4 0.0 6.9e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain HET PF06985.11 KPI42425.1 - 7.2e-24 84.8 0.2 1.5e-23 83.8 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KPI42426.1 - 5.8e-21 74.8 0.0 1.2e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42426.1 - 3.3e-12 46.5 0.0 4.4e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI42426.1 - 4.9e-08 33.1 0.0 7.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI42426.1 - 0.00093 18.7 0.1 0.0029 17.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KPI42426.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KPI42426.1 - 0.013 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPI42426.1 - 0.021 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 KPI42427.1 - 4e-65 220.4 18.0 4.6e-65 220.2 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42427.1 - 1.4e-09 37.4 26.8 1.4e-09 37.4 26.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily His_Phos_1 PF00300.22 KPI42428.1 - 5.5e-13 49.0 3.0 1.4e-08 34.7 0.1 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Brix PF04427.18 KPI42429.1 - 2e-24 86.8 0.0 2.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain CLTH PF10607.9 KPI42430.1 - 1.1e-25 90.3 0.0 2.2e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C2H2_9 PF16293.5 KPI42430.1 - 0.0044 16.8 0.1 0.017 15.0 0.0 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (1 copy) LisH PF08513.11 KPI42430.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 LisH Snf7 PF03357.21 KPI42430.1 - 0.0064 16.1 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Snf7 CENP-F_leu_zip PF10473.9 KPI42430.1 - 0.071 13.1 1.5 0.15 12.1 1.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RRP36 PF06102.12 KPI42430.1 - 0.091 12.7 0.5 0.16 11.9 0.5 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF1077 PF06417.12 KPI42432.1 - 1.6e-46 157.1 2.3 2.1e-46 156.7 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ABA_GPCR PF12430.8 KPI42433.1 - 5.6e-50 169.6 1.7 5.6e-50 169.6 1.7 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KPI42433.1 - 3.6e-22 78.2 0.0 9.5e-21 73.7 0.0 2.5 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Methyltransf_16 PF10294.9 KPI42434.1 - 0.00025 20.8 0.0 0.044 13.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase 2OG-FeII_Oxy_2 PF13532.6 KPI42435.1 - 2.7e-09 37.5 0.0 8.7e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Opiods_neuropep PF01160.18 KPI42435.1 - 0.075 13.1 2.0 0.17 12.0 2.0 1.6 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Endonuc_Holl PF10107.9 KPI42435.1 - 0.31 10.9 0.1 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Lyase_1 PF00206.20 KPI42437.1 - 3.6e-90 302.5 0.0 4.9e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KPI42437.1 - 9.7e-23 80.7 0.0 2.7e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF3761 PF12587.8 KPI42438.1 - 0.039 14.4 1.3 0.11 12.9 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3761) EST1_DNA_bind PF10373.9 KPI42439.1 - 1e-05 25.2 0.2 2.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain ALMS_motif PF15309.6 KPI42439.1 - 0.25 11.8 1.0 0.85 10.1 1.0 1.9 1 1 0 1 1 1 0 ALMS motif PBD PF00786.28 KPI42440.1 - 0.013 15.8 0.1 0.038 14.3 0.1 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain YqgC PF17430.2 KPI42440.1 - 0.02 15.0 0.2 1.9 8.6 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized YqgC-like SRF-TF PF00319.18 KPI42441.1 - 3.1e-21 74.6 0.1 4.5e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GNVR PF13807.6 KPI42442.1 - 4.4 7.3 5.6 2.6 8.0 0.0 2.5 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase FSH1 PF03959.13 KPI42443.1 - 2.3e-19 69.9 0.0 3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KPI42443.1 - 0.00044 20.9 1.4 0.00063 20.4 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KPI42443.1 - 0.043 13.6 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase PUF PF00806.19 KPI42444.1 - 8.3e-56 182.7 5.9 6e-08 32.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat LOB PF03195.14 KPI42444.1 - 0.14 12.8 0.1 0.83 10.3 0.1 2.3 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain AMP-binding PF00501.28 KPI42445.1 - 2.4e-54 184.6 0.0 3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI42445.1 - 1.5e-10 41.9 0.0 2.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HET PF06985.11 KPI42446.1 - 4e-30 105.1 0.0 9e-30 104.0 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Haem_degrading PF03928.14 KPI42447.1 - 4.2e-28 97.8 0.1 5e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Zn_clus PF00172.18 KPI42448.1 - 2.4e-08 34.0 7.8 3.5e-08 33.4 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACOX PF01756.19 KPI42449.1 - 1e-31 109.9 0.4 1.2e-29 103.2 0.0 2.7 1 1 1 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KPI42449.1 - 6.1e-22 78.5 0.3 1.3e-21 77.4 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPI42449.1 - 2.3e-06 27.7 0.0 5.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KPI42449.1 - 7.8e-06 26.2 1.2 0.00092 19.4 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain DUF4953 PF16313.5 KPI42449.1 - 0.039 13.2 0.1 0.086 12.0 0.1 1.5 1 0 0 1 1 1 0 Met-zincin PAC4 PF16093.5 KPI42449.1 - 0.088 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 MFS_1 PF07690.16 KPI42450.1 - 1.4e-30 106.4 35.5 1.9e-30 106.0 35.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KPI42450.1 - 0.023 13.0 5.5 0.068 11.4 5.5 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Mpv17_PMP22 PF04117.12 KPI42451.1 - 6.5e-18 64.7 1.2 1.7e-17 63.4 1.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family CdiA_C PF18451.1 KPI42451.1 - 0.052 13.8 0.2 0.092 13.0 0.2 1.4 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain Fungal_trans_2 PF11951.8 KPI42452.1 - 2.1e-23 82.7 0.4 3.2e-23 82.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 KPI42452.1 - 0.025 14.1 0.0 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Isochorismatase PF00857.20 KPI42453.1 - 1.6e-07 31.7 0.0 2.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Spermine_synth PF01564.17 KPI42453.1 - 0.0017 17.8 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF924 PF06041.11 KPI42454.1 - 6e-52 176.4 0.0 6.9e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Abhydrolase_1 PF00561.20 KPI42455.1 - 5.1e-49 167.2 0.0 1.4e-48 165.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42455.1 - 6e-06 27.0 0.3 8.8e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KPI42455.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF410 PF04190.13 KPI42456.1 - 6.6e-77 258.7 0.0 8.5e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF1989 PF09347.10 KPI42457.1 - 3.7e-48 163.3 0.1 1.3e-47 161.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 KPI42457.1 - 3.8e-17 62.3 0.0 6.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPI42457.1 - 5.8e-08 32.6 0.0 9.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KPI42457.1 - 0.13 10.5 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) NDUF_B12 PF08122.12 KPI42458.1 - 2.9e-24 84.9 1.7 4e-24 84.4 1.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family His_Phos_1 PF00300.22 KPI42459.1 - 2.3e-08 34.0 0.0 0.00045 20.0 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) adh_short_C2 PF13561.6 KPI42461.1 - 2.3e-57 194.3 0.4 2.4e-54 184.4 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42461.1 - 2e-47 161.2 0.2 8.4e-45 152.6 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KPI42461.1 - 0.00033 20.2 0.1 0.0011 18.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KPI42461.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 KR domain FRB_dom PF08771.11 KPI42461.1 - 0.099 13.1 0.0 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Acyl-CoA_ox_N PF14749.6 KPI42462.1 - 1.5e-17 64.3 1.1 2.2e-17 63.8 0.3 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KPI42462.1 - 3e-09 36.9 0.0 6.8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 KPI42462.1 - 3.7e-08 33.1 0.0 9.1e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 KPI42462.1 - 0.0022 18.2 0.0 0.006 16.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cu-oxidase_2 PF07731.14 KPI42463.1 - 1.5e-47 160.7 9.3 2.4e-39 134.2 2.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KPI42463.1 - 6.9e-40 135.8 6.6 3.6e-39 133.5 0.9 3.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KPI42463.1 - 2.2e-36 125.4 1.8 3.6e-34 118.2 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KPI42463.1 - 0.017 15.2 0.0 14 5.8 0.0 3.8 4 0 0 4 4 4 0 Cupredoxin-like domain Phosphodiest PF01663.22 KPI42465.1 - 1.3e-11 44.7 0.6 2e-11 44.1 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KPI42465.1 - 0.0017 17.8 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KPI42465.1 - 0.059 12.7 1.7 0.097 12.0 1.7 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily EptA_B_N PF08019.12 KPI42465.1 - 2.6 7.9 9.2 0.11 12.4 1.4 2.8 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Ytp1 PF10355.9 KPI42466.1 - 1.5e-70 237.6 18.2 6.9e-70 235.4 18.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KPI42466.1 - 1.9e-28 98.3 0.8 1.9e-28 98.3 0.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) NRDE-2 PF08424.10 KPI42467.1 - 1.5e-77 260.9 2.4 1.5e-77 260.9 2.4 2.9 2 1 1 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KPI42467.1 - 0.00074 20.1 0.1 54 5.0 0.0 5.7 7 1 1 8 8 8 0 Tetratricopeptide repeat TEA PF01285.18 KPI42467.1 - 0.036 14.2 0.0 0.23 11.6 0.0 2.4 1 0 0 1 1 1 0 TEA/ATTS domain Rad54_N PF08658.10 KPI42467.1 - 0.075 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Rad54 N terminal TPR_17 PF13431.6 KPI42467.1 - 0.19 12.2 0.2 0.79 10.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.27 KPI42468.1 - 7.5e-62 205.3 0.1 6e-21 74.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UBA_4 PF14555.6 KPI42469.1 - 2.4e-06 27.2 0.2 5.7e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Endopep_inhib PF16800.5 KPI42469.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor DASH_Spc19 PF08287.11 KPI42469.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.5 3 0 0 3 3 3 0 Spc19 DUF5082 PF16888.5 KPI42469.1 - 0.16 12.3 1.4 0.42 10.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) UIM PF02809.20 KPI42469.1 - 0.18 11.8 6.9 0.5 10.4 6.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Spc7 PF08317.11 KPI42469.1 - 4.8 6.0 6.4 18 4.1 6.4 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein PAF-AH_p_II PF03403.13 KPI42470.1 - 7.2e-35 120.2 0.0 4.2e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KPI42470.1 - 0.038 13.2 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF5538 PF17692.1 KPI42470.1 - 0.079 13.0 0.4 0.26 11.3 0.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Chlorophyllase2 PF12740.7 KPI42470.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme WD40 PF00400.32 KPI42471.1 - 1.5e-60 199.7 7.2 4.3e-09 36.9 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI42471.1 - 4.6e-18 65.3 0.1 2e-05 24.8 0.0 6.6 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KPI42471.1 - 1.5e-16 60.4 13.1 2.9e-16 59.5 13.1 1.5 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KPI42471.1 - 8.9e-09 35.1 0.0 0.0012 18.2 0.0 5.0 3 1 2 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 KPI42471.1 - 1.1e-06 27.8 0.0 0.8 8.6 0.0 4.4 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KPI42471.1 - 6.9e-05 22.3 0.0 0.13 11.5 0.0 3.0 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KPI42471.1 - 0.00031 20.7 0.0 0.18 11.7 0.0 3.3 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KPI42471.1 - 0.0029 16.3 0.3 1.5 7.4 0.1 3.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KPI42471.1 - 0.0041 15.7 0.0 0.017 13.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KPI42471.1 - 0.13 12.3 0.0 39 4.3 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 KPI42471.1 - 0.15 11.1 0.0 0.77 8.8 0.0 2.0 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 KPI42471.1 - 0.22 10.2 0.1 23 3.6 0.1 3.2 2 1 2 4 4 4 0 Nup133 N terminal like Proteasome_A_N PF10584.9 KPI42471.1 - 0.25 11.1 2.9 7.5 6.3 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature SET PF00856.28 KPI42472.1 - 7.3e-19 68.8 0.9 2.1e-18 67.3 0.0 2.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KPI42472.1 - 3.7e-12 46.9 3.8 3.7e-12 46.9 3.8 2.1 2 0 0 2 2 2 1 Pre-SET motif Methyltransf_3 PF01596.17 KPI42472.1 - 0.037 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Metallothio_PEC PF02068.16 KPI42472.1 - 0.93 9.9 14.0 1.1 9.6 0.8 3.3 3 0 0 3 3 3 0 Plant PEC family metallothionein Fungal_trans PF04082.18 KPI42473.1 - 5.3e-13 48.6 1.8 6.5e-13 48.3 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2155 PF09923.9 KPI42474.1 - 0.08 13.2 0.0 2.2 8.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2155) L27 PF02828.16 KPI42474.1 - 0.19 11.5 0.9 0.44 10.4 0.1 2.0 2 0 0 2 2 2 0 L27 domain Aminotran_3 PF00202.21 KPI42475.1 - 1.9e-121 405.6 0.0 2.2e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Vps5 PF09325.10 KPI42476.1 - 4.6e-11 42.7 3.3 8.1e-11 41.9 3.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KPI42476.1 - 1.3e-08 34.8 0.0 2.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KPI42476.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein TPR_12 PF13424.6 KPI42476.1 - 0.29 11.5 3.9 0.58 10.5 0.3 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3347 PF11827.8 KPI42476.1 - 0.61 10.3 2.4 1.6 8.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) TFIIA PF03153.13 KPI42476.1 - 2.4 8.1 13.9 2.9 7.8 8.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rsm22 PF09243.10 KPI42477.1 - 3.1e-24 85.7 0.0 2.3e-11 43.5 0.0 3.6 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 IBR PF01485.21 KPI42478.1 - 2.4e-06 27.7 27.2 0.0026 18.0 1.1 4.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain GRDP-like PF07173.12 KPI42478.1 - 0.012 16.2 0.1 0.063 13.9 0.0 2.4 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like Cytochrome_CBB3 PF13442.6 KPI42478.1 - 0.035 14.4 0.1 5.8 7.3 0.1 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III PPR PF01535.20 KPI42479.1 - 9.9e-05 22.3 0.0 0.014 15.6 0.0 3.0 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 KPI42479.1 - 0.022 15.0 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family IF-2B PF01008.17 KPI42480.1 - 2.1e-15 56.7 1.5 1e-10 41.3 0.1 2.2 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.28 KPI42480.1 - 1.3e-06 28.5 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain GRAS PF03514.14 KPI42480.1 - 0.1 11.5 0.3 0.15 11.0 0.3 1.2 1 0 0 1 1 1 0 GRAS domain family Acetyltransf_1 PF00583.25 KPI42481.1 - 2.4e-11 43.9 0.0 4.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI42481.1 - 3.1e-10 40.1 0.0 4.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI42481.1 - 6.3e-08 32.9 0.0 9.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI42481.1 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KPI42481.1 - 0.14 12.2 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4202 PF13875.6 KPI42482.1 - 2.7e-77 258.9 0.8 3e-77 258.7 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) GFA PF04828.14 KPI42483.1 - 1.9e-11 44.1 0.0 2.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldedh PF00171.22 KPI42484.1 - 2.3e-138 461.6 4.3 6.5e-138 460.1 4.3 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI42484.1 - 0.0018 17.7 0.0 0.015 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Bax1-I PF01027.20 KPI42485.1 - 6.6e-36 124.1 10.0 9.9e-36 123.5 10.0 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Atthog PF18800.1 KPI42485.1 - 0.049 13.5 0.0 4.4 7.2 0.0 2.3 1 1 1 2 2 2 0 Attenuator of Hedgehog PQ-loop PF04193.14 KPI42486.1 - 9.5e-37 124.6 11.2 7.9e-19 67.2 4.4 2.6 2 0 0 2 2 2 2 PQ loop repeat Steroid_dh PF02544.16 KPI42486.1 - 0.12 12.4 4.2 1 9.3 0.6 2.5 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase HTH_Bact PF18768.1 KPI42486.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain MFS_1 PF07690.16 KPI42487.1 - 3.8e-27 95.1 37.2 3.8e-27 95.1 37.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.28 KPI42488.1 - 2.3e-16 60.4 0.0 4e-16 59.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.18 KPI42489.1 - 3.2e-08 33.5 12.9 7e-08 32.4 12.9 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.28 KPI42489.1 - 9.4e-07 29.4 0.0 2.3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 SET domain Swi5 PF07061.11 KPI42490.1 - 3.6e-12 46.2 0.4 1.5e-11 44.2 0.4 2.0 1 1 0 1 1 1 1 Swi5 MGC-24 PF05283.11 KPI42491.1 - 1.5 9.3 4.3 3.5 8.1 4.3 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adaptin_N PF01602.20 KPI42492.1 - 2.5e-122 409.1 8.7 3.2e-122 408.8 8.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPI42492.1 - 8.6e-53 178.7 9.0 7e-51 172.5 0.2 3.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPI42492.1 - 1.2e-13 51.2 5.5 1.6e-08 34.9 0.1 5.2 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KPI42492.1 - 2.6e-08 33.4 6.8 0.014 15.6 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KPI42492.1 - 5e-06 26.9 1.7 0.057 13.9 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.23 KPI42492.1 - 4.9e-05 23.2 1.2 3.2 7.9 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KPI42492.1 - 0.00059 19.5 0.9 0.58 9.7 0.0 3.5 3 1 0 3 3 3 2 CLASP N terminal FANCI_S2 PF14676.6 KPI42492.1 - 0.0022 18.4 1.5 2.4 8.5 0.0 3.5 3 1 0 3 3 3 1 FANCI solenoid 2 Atx10homo_assoc PF09759.9 KPI42492.1 - 0.0065 16.5 0.0 12 6.0 0.0 4.0 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 KPI42492.1 - 0.015 15.5 2.8 1.7 8.9 0.0 4.1 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KPI42492.1 - 0.063 13.7 0.8 13 6.3 0.0 4.2 2 1 3 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain N_Asn_amidohyd PF14736.6 KPI42492.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Epimerase PF01370.21 KPI42493.1 - 4.7e-12 45.9 0.0 7.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI42493.1 - 2.2e-08 34.2 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPI42493.1 - 7.5e-07 29.6 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KPI42493.1 - 9.8e-06 25.3 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KPI42493.1 - 0.0015 18.0 0.0 0.0061 16.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DXP_reductoisom PF02670.16 KPI42493.1 - 0.016 15.9 0.0 0.026 15.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.12 KPI42493.1 - 0.043 13.0 0.0 0.09 11.9 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 KPI42493.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 KPI42493.1 - 0.16 12.8 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Syntaxin-18_N PF10496.9 KPI42494.1 - 1.8e-08 34.5 0.0 6e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KPI42494.1 - 0.0085 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 SNARE domain WXG100 PF06013.12 KPI42494.1 - 0.94 9.7 5.8 4.2 7.7 0.1 4.0 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DUF16 PF01519.16 KPI42494.1 - 2.9 8.4 8.7 2.3 8.7 1.7 3.2 4 0 0 4 4 4 0 Protein of unknown function DUF16 NOT2_3_5 PF04153.18 KPI42496.1 - 3.9e-24 85.2 0.0 8e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family adh_short PF00106.25 KPI42497.1 - 5.6e-08 32.5 0.0 1.3e-06 28.0 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42497.1 - 0.022 14.3 0.0 0.095 12.2 0.0 2.0 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 KPI42500.1 - 4.6e-35 121.2 34.1 5.4e-35 121.0 34.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MLANA PF14991.6 KPI42500.1 - 4.1 7.7 4.3 6.7 7.0 0.1 2.8 3 0 0 3 3 3 0 Protein melan-A MPS2 PF17060.5 KPI42501.1 - 0.00044 19.6 2.8 0.00044 19.6 2.8 1.9 1 1 1 2 2 2 1 Monopolar spindle protein 2 FlaC_arch PF05377.11 KPI42501.1 - 0.033 14.6 1.7 0.091 13.2 1.7 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3837 PF12939.7 KPI42501.1 - 0.15 12.5 1.2 7.8 7.0 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) UPF0242 PF06785.11 KPI42501.1 - 7 6.7 9.2 6.4 6.8 2.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BPL_N PF09825.9 KPI42502.1 - 9.4e-143 475.8 0.0 2.2e-142 474.6 0.0 1.6 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KPI42502.1 - 1.4e-23 83.2 0.1 2.5e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KPI42502.1 - 0.002 18.0 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SAP PF02037.27 KPI42503.1 - 2.8e-05 23.8 0.1 4.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 SAP domain Rer1 PF03248.13 KPI42505.1 - 3e-76 254.9 2.0 5.2e-76 254.1 2.0 1.3 1 0 0 1 1 1 1 Rer1 family Asp_protease PF09668.10 KPI42505.1 - 2.3e-51 172.8 0.1 3.7e-51 172.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KPI42505.1 - 7.2e-20 71.4 0.0 2.1e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KPI42505.1 - 9.4e-09 35.8 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KPI42505.1 - 5.5e-07 29.2 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.20 KPI42505.1 - 0.00049 20.4 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KPI42505.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Cation_ATPase_C PF00689.21 KPI42505.1 - 0.022 14.5 2.8 0.83 9.3 2.9 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus UBA_4 PF14555.6 KPI42505.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain TFIIA PF03153.13 KPI42505.1 - 5.8 6.8 16.5 3 7.7 5.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2423 PF10338.9 KPI42506.1 - 3e-16 59.4 5.7 3e-16 59.4 5.7 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Ribosomal_S9 PF00380.19 KPI42507.1 - 8.8e-38 129.5 0.3 1.6e-37 128.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HET PF06985.11 KPI42508.1 - 4.8e-23 82.1 0.0 9.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-RRPl_C4 PF17026.5 KPI42508.1 - 0.17 12.0 1.2 0.22 11.6 0.1 1.7 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type RibD_C PF01872.17 KPI42509.1 - 3.4e-29 102.1 0.0 8.8e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 RibD C-terminal domain adh_short PF00106.25 KPI42510.1 - 1.5e-29 102.9 0.4 5.2e-24 84.8 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42510.1 - 9.9e-19 67.8 0.1 1.3e-16 60.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI42510.1 - 8.9e-09 35.5 0.3 1.3e-08 35.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI42510.1 - 3.3e-05 23.5 0.0 5.3e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KPI42510.1 - 0.0086 15.8 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 KPI42510.1 - 0.014 15.3 0.2 0.039 13.9 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KPI42510.1 - 0.014 14.8 0.3 0.039 13.3 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KPI42510.1 - 0.018 15.5 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KPI42510.1 - 0.035 14.2 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PRTase_2 PF15609.6 KPI42510.1 - 0.039 13.4 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Polysacc_synt_2 PF02719.15 KPI42510.1 - 0.059 12.5 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GATase_3 PF07685.14 KPI42510.1 - 0.1 12.2 0.1 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pep3_Vps18 PF05131.14 KPI42514.1 - 1.9e-45 154.4 0.0 1e-44 152.0 0.0 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KPI42514.1 - 5.3e-10 39.3 10.9 7.8e-07 29.1 0.3 3.7 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KPI42514.1 - 3.1e-05 24.4 0.2 9.3e-05 22.8 0.1 1.9 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KPI42514.1 - 0.00038 20.0 0.2 0.00087 18.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KPI42514.1 - 0.00038 20.2 0.5 0.0011 18.8 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI42514.1 - 0.00088 19.6 0.9 0.0026 18.0 0.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPI42514.1 - 0.0015 18.5 0.4 0.0035 17.3 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KPI42514.1 - 0.0022 17.7 4.6 0.0022 17.7 4.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger RPN1_RPN2_N PF17781.1 KPI42514.1 - 0.012 15.0 0.7 0.026 13.9 0.7 1.5 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain zf-RING_UBOX PF13445.6 KPI42514.1 - 0.026 14.5 0.7 0.073 13.1 0.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger PspA_IM30 PF04012.12 KPI42514.1 - 0.031 13.9 2.5 0.062 12.9 0.5 2.2 2 0 0 2 2 2 0 PspA/IM30 family zf-C3HC4 PF00097.25 KPI42514.1 - 0.039 13.8 0.4 0.093 12.6 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Syntaxin-6_N PF09177.11 KPI42514.1 - 0.043 14.4 2.9 1.7 9.3 0.2 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf-rbx1 PF12678.7 KPI42514.1 - 0.045 14.1 0.2 0.3 11.4 0.4 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF2175 PF09943.9 KPI42514.1 - 0.072 13.4 1.4 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF1664 PF07889.12 KPI42514.1 - 0.14 12.2 1.4 0.36 10.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med4 PF10018.9 KPI42514.1 - 2.4 7.8 4.7 0.85 9.3 0.2 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-C3H2C3 PF17122.5 KPI42514.1 - 3 7.9 4.8 0.8 9.8 1.2 1.9 2 0 0 2 2 2 0 Zinc-finger RAI1 PF08652.11 KPI42515.1 - 1.2e-25 89.4 0.3 3.8e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease DUF3738 PF12543.8 KPI42516.1 - 0.055 13.6 0.1 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3738) ATP-synt_C PF00137.21 KPI42517.1 - 1.1e-25 89.7 34.1 6.5e-16 58.4 13.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Sugar_tr PF00083.24 KPI42518.1 - 6.8e-51 173.5 7.2 4.7e-31 108.2 2.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42518.1 - 1.6e-20 73.3 14.8 1.1e-13 50.9 0.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI42518.1 - 0.0011 17.9 5.8 0.097 11.5 0.1 2.1 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KPI42518.1 - 0.015 13.7 6.7 0.056 11.9 0.0 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KPI42518.1 - 2.4 6.3 7.5 4.5 5.4 0.1 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4198 PF10670.9 KPI42519.1 - 0.0075 16.7 0.5 0.0093 16.4 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) DUF2067 PF09840.9 KPI42519.1 - 0.15 11.6 2.3 0.22 11.1 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) DUF2161 PF09929.9 KPI42519.1 - 3.1 8.0 7.9 1.7 8.7 4.8 2.2 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Sugar_tr PF00083.24 KPI42520.1 - 8.7e-77 258.9 19.5 1e-76 258.6 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42520.1 - 2.9e-12 46.2 32.7 4.1e-08 32.5 18.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4188 PF13826.6 KPI42521.1 - 2.3e-27 95.7 0.0 3.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF3291 PF11695.8 KPI42521.1 - 0.0071 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) vMSA PF00695.19 KPI42521.1 - 0.08 12.0 0.3 0.13 11.4 0.3 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Dabb PF07876.12 KPI42521.1 - 0.15 12.7 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain CMD PF02627.20 KPI42522.1 - 5.9e-21 74.3 0.2 8.4e-21 73.8 0.2 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family AMP-binding PF00501.28 KPI42523.1 - 5.4e-95 318.5 0.0 6.4e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI42523.1 - 3e-18 66.5 0.0 6.7e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3658 PF12395.8 KPI42523.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function Sugar_tr PF00083.24 KPI42525.1 - 2.3e-45 155.3 15.3 5e-45 154.2 15.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42525.1 - 1.7e-18 66.7 27.5 1.7e-18 66.7 27.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UBM PF14377.6 KPI42527.1 - 0.034 13.6 0.4 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin binding region SseB PF07179.12 KPI42527.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.6 2 0 0 2 2 2 0 SseB protein N-terminal domain FAD_binding_3 PF01494.19 KPI42528.1 - 5.1e-07 29.3 0.0 3.6e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain SnoaL_4 PF13577.6 KPI42529.1 - 8.6e-07 29.1 0.4 1.2e-06 28.7 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain Helicase_C PF00271.31 KPI42530.1 - 3.9e-11 43.3 0.0 1.4e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KPI42530.1 - 1.4e-07 31.8 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KPI42530.1 - 4.2e-06 26.6 0.8 0.03 14.1 0.0 2.9 2 1 1 3 3 3 2 DEAD/DEAH box helicase AAA_30 PF13604.6 KPI42530.1 - 0.0016 18.2 0.0 0.005 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain HA2 PF04408.23 KPI42530.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 4.4 3 2 1 4 4 4 1 Helicase associated domain (HA2) AAA_22 PF13401.6 KPI42530.1 - 0.0027 18.0 0.2 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KPI42530.1 - 0.01 15.9 0.0 1.9 8.5 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KPI42530.1 - 0.031 13.5 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KPI42530.1 - 0.087 12.2 1.3 0.5 9.7 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 KPI42530.1 - 0.65 10.5 0.0 0.65 10.5 0.0 3.5 3 1 1 4 4 4 0 AAA domain Abhydrolase_2 PF02230.16 KPI42531.1 - 1.9e-55 188.0 0.0 2.3e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KPI42531.1 - 1.1e-05 24.8 1.5 0.0021 17.3 0.1 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPI42531.1 - 1.6e-05 24.5 0.2 0.00047 19.7 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KPI42531.1 - 0.00014 21.7 0.0 0.00087 19.0 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KPI42531.1 - 0.00087 19.2 0.0 0.079 12.8 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42531.1 - 0.0033 18.0 0.0 0.0071 17.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 KPI42531.1 - 0.0056 16.2 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 KPI42531.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 KPI42531.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Ku PF02735.16 KPI42532.1 - 1.8e-43 148.7 0.0 7.5e-43 146.6 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KPI42532.1 - 1.4e-35 123.1 0.0 2.5e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KPI42532.1 - 1.2e-24 86.7 0.1 3e-24 85.5 0.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KPI42532.1 - 6.6e-13 48.1 0.0 1.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KPI42532.1 - 0.007 16.0 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 HeH/LEM domain MARVEL PF01284.23 KPI42533.1 - 1.4e-06 28.4 5.0 1.9e-06 28.0 5.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain TMEM223 PF14640.6 KPI42533.1 - 0.14 12.3 0.5 0.21 11.7 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 DUF2456 PF10445.9 KPI42533.1 - 0.82 9.8 5.9 0.53 10.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2456) DUF4199 PF13858.6 KPI42533.1 - 3.3 8.1 7.1 26 5.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) BTB PF00651.31 KPI42534.1 - 1.7e-10 41.1 0.1 5.4e-09 36.3 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain DUF2461 PF09365.10 KPI42535.1 - 2.7e-75 252.9 0.0 3.7e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PPP4R2 PF09184.11 KPI42535.1 - 2.3 7.7 10.3 1.1 8.8 8.0 1.5 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 KPI42535.1 - 2.9 6.0 7.1 3.8 5.6 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KPI42535.1 - 5.9 5.0 6.3 8.1 4.6 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Taxilin PF09728.9 KPI42536.1 - 0.28 10.3 41.2 0.95 8.6 21.1 2.6 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Baculo_PEP_C PF04513.12 KPI42536.1 - 6 6.9 8.9 14 5.7 5.3 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Viral_coat PF00729.18 KPI42537.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral coat protein (S domain) SnoaL PF07366.12 KPI42538.1 - 1.3e-22 79.9 0.0 1.5e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KPI42538.1 - 1.5e-09 38.4 0.0 1.8e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain CFEM PF05730.11 KPI42539.1 - 9.6e-09 35.2 9.2 2e-08 34.2 9.2 1.6 1 0 0 1 1 1 1 CFEM domain Tyrosinase PF00264.20 KPI42540.1 - 7.6e-26 91.8 0.1 1.4e-25 90.9 0.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Amidohydro_2 PF04909.14 KPI42541.1 - 1e-32 114.1 0.0 1.3e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase UPF0061 PF02696.14 KPI42542.1 - 0.084 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF2205 PF10224.9 KPI42542.1 - 0.18 11.8 0.4 0.31 11.1 0.4 1.3 1 0 0 1 1 1 0 Short coiled-coil protein ZapB PF06005.12 KPI42542.1 - 0.27 11.7 1.5 0.49 10.9 1.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB CGI-121 PF08617.10 KPI42543.1 - 5.7e-52 176.1 0.1 6.5e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 CUE PF02845.16 KPI42543.1 - 0.13 12.0 0.4 1.3 8.8 0.0 2.8 4 0 0 4 4 4 0 CUE domain GPI-anchored PF10342.9 KPI42544.1 - 8.4e-06 26.5 0.8 2.1e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 KPI42544.1 - 0.011 15.2 0.2 0.023 14.1 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Methyltransf_2 PF00891.18 KPI42545.1 - 9.1e-21 74.1 0.0 2.3e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KPI42545.1 - 0.0021 18.7 0.0 0.0064 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Striatin PF08232.12 KPI42546.1 - 0.0046 17.6 0.5 0.0046 17.6 0.5 2.5 2 1 0 2 2 2 1 Striatin family DUF4482 PF14818.6 KPI42546.1 - 0.051 14.4 1.8 0.11 13.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) CCDC-167 PF15188.6 KPI42546.1 - 1.4 9.3 2.9 1.1 9.6 0.7 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 adh_short PF00106.25 KPI42547.1 - 1.4e-05 24.7 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42547.1 - 0.00036 20.2 0.0 0.00095 18.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KPI42548.1 - 7.8e-59 199.6 0.0 3.9e-50 171.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Got1 PF04178.12 KPI42550.1 - 6.3e-15 55.6 14.0 8.2e-15 55.2 14.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family AgrD PF05931.11 KPI42550.1 - 0.084 12.9 1.5 0.22 11.6 1.5 1.7 1 0 0 1 1 1 0 Staphylococcal AgrD protein CPP1-like PF11833.8 KPI42550.1 - 0.36 10.5 2.2 0.41 10.3 2.2 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Slx4 PF09494.10 KPI42551.1 - 2.5e-22 78.6 0.3 4.6e-22 77.7 0.3 1.5 1 0 0 1 1 1 1 Slx4 endonuclease PhyH PF05721.13 KPI42552.1 - 3.1e-06 27.6 0.1 1.4e-05 25.4 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Propep_M14 PF02244.16 KPI42552.1 - 0.13 12.7 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide DHO_dh PF01180.21 KPI42553.1 - 1.5e-15 57.2 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase KH_1 PF00013.29 KPI42553.1 - 0.018 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 KH domain NMO PF03060.15 KPI42553.1 - 0.31 10.4 3.7 0.47 9.8 3.7 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase F-box-like PF12937.7 KPI42554.1 - 7.1e-06 25.8 0.1 2.3e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI42554.1 - 0.00049 19.9 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KPI42554.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 F-box p450 PF00067.22 KPI42555.1 - 1.6e-60 205.2 0.0 2.3e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 IL32 PF15225.6 KPI42555.1 - 0.13 12.7 0.0 0.91 9.9 0.0 2.1 2 0 0 2 2 2 0 Interleukin 32 Fungal_trans PF04082.18 KPI42556.1 - 0.0079 15.3 0.4 0.012 14.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VASt PF16016.5 KPI42557.1 - 5.9e-34 117.7 0.0 1e-33 116.9 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KPI42557.1 - 7.1e-22 77.4 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain CAP PF00188.26 KPI42558.1 - 3.1e-07 31.3 6.4 1.2e-05 26.2 0.2 2.7 2 1 0 2 2 2 2 Cysteine-rich secretory protein family Hydrolase_6 PF13344.6 KPI42559.1 - 1.2e-26 92.8 0.0 2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_tranf_2_4 PF13704.6 KPI42559.1 - 0.14 12.7 0.0 0.66 10.5 0.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase family 2 PAPA-1 PF04795.12 KPI42561.1 - 0.013 16.3 0.3 2.3 9.1 0.0 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region A2M_recep PF07677.14 KPI42561.1 - 0.036 14.8 0.0 0.079 13.7 0.0 1.5 1 0 0 1 1 1 0 A-macroglobulin receptor binding domain ECH_1 PF00378.20 KPI42562.1 - 1.6e-59 201.3 1.0 2e-59 201.0 1.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KPI42562.1 - 1.5e-20 74.0 2.7 6.9e-18 65.2 0.5 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Ribosomal_L28e PF01778.17 KPI42563.1 - 8.3e-32 110.3 3.6 1e-31 110.0 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Pyr_redox_2 PF07992.14 KPI42564.1 - 3.3e-10 39.7 0.4 6.6e-06 25.6 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI42564.1 - 2.4e-05 23.7 0.0 4.9 6.3 0.0 4.1 4 0 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI42564.1 - 0.00034 19.2 0.0 0.051 12.0 0.0 2.5 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI42564.1 - 0.0059 16.8 2.0 0.055 13.7 1.4 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI42564.1 - 0.02 14.9 2.3 4 7.4 0.6 3.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KPI42565.1 - 2.5e-10 40.1 2.4 3.7e-05 23.1 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI42565.1 - 0.00017 20.9 0.1 0.012 14.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI42565.1 - 0.0025 17.4 0.1 0.38 10.3 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI42565.1 - 0.0067 17.0 0.3 0.017 15.7 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPI42565.1 - 0.11 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Asp PF00026.23 KPI42566.1 - 4.9e-47 160.9 1.3 3.8e-46 158.0 1.3 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI42566.1 - 2.5e-07 31.1 1.3 1.2e-05 25.7 0.6 3.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI42566.1 - 0.0034 18.0 0.0 0.22 12.2 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KPI42566.1 - 0.048 13.4 0.0 0.42 10.4 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KPI42566.1 - 0.13 12.9 0.0 2.4 8.8 0.0 3.0 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DSPc PF00782.20 KPI42567.1 - 1.9e-07 30.9 0.0 0.0073 16.1 0.0 2.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain DUF1295 PF06966.12 KPI42568.1 - 9e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KPI42568.1 - 0.083 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase Antig_Caf1 PF09255.10 KPI42568.1 - 0.11 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Caf1 Capsule antigen Ion_trans PF00520.31 KPI42569.1 - 9.3e-122 404.9 77.3 1.8e-37 128.9 0.6 4.9 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KPI42569.1 - 0.0026 17.5 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Y_phosphatase3 PF13350.6 KPI42570.1 - 5.4e-38 131.3 0.0 2.8e-21 76.6 0.0 3.1 2 1 0 2 2 2 2 Tyrosine phosphatase family DLIC PF05783.11 KPI42570.1 - 6.5e-24 84.6 10.0 1.1e-15 57.5 0.0 3.9 1 1 2 4 4 4 2 Dynein light intermediate chain (DLIC) CNH PF00780.22 KPI42571.1 - 4e-71 239.8 0.0 2.7e-70 237.1 0.0 2.0 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 KPI42571.1 - 5.2e-38 131.1 0.0 9.2e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KPI42571.1 - 2.6e-37 127.9 0.0 5.7e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KPI42571.1 - 2.5e-13 49.9 0.1 7e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nas2_N PF18265.1 KPI42572.1 - 9.8e-31 105.5 0.1 1.5e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KPI42572.1 - 1e-06 28.4 0.2 3.1e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KPI42572.1 - 1.1e-05 25.7 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KPI42572.1 - 0.0001 22.6 0.0 0.0002 21.6 0.0 1.6 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KPI42572.1 - 0.0015 18.9 0.1 0.0071 16.7 0.1 2.0 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain TANGO2 PF05742.12 KPI42573.1 - 3.2e-68 230.5 0.0 3.7e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Pkinase PF00069.25 KPI42574.1 - 3.8e-14 52.7 0.1 3.9e-10 39.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42574.1 - 4.3e-06 26.2 0.0 3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PPP5 PF08321.12 KPI42575.1 - 6.2e-32 109.8 0.8 1.3e-31 108.7 0.8 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KPI42575.1 - 6.6e-32 111.7 0.1 1e-31 111.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.6 KPI42575.1 - 2.2e-05 24.0 0.7 0.0047 16.6 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 KPI42575.1 - 0.00033 20.4 1.3 0.0064 16.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPI42575.1 - 0.00072 20.1 0.6 0.59 10.8 0.5 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI42575.1 - 0.0027 17.7 1.7 0.056 13.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KPI42575.1 - 0.0059 16.9 1.3 3.2 8.3 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KPI42575.1 - 0.036 14.9 1.4 5 8.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Urm1 PF09138.11 KPI42577.1 - 8.3e-33 112.6 0.0 1.9e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KPI42577.1 - 0.00023 21.7 0.0 0.00038 21.0 0.0 1.3 1 0 0 1 1 1 1 ThiS family ADH_N PF08240.12 KPI42578.1 - 3.9e-06 26.7 0.2 1.6e-05 24.8 0.2 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_20 PF00728.22 KPI42579.1 - 1.2e-25 90.7 0.6 1.3e-22 80.7 0.6 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KPI42579.1 - 1.1e-07 32.7 0.1 2.3e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GCD14 PF08704.10 KPI42580.1 - 2.3e-58 197.8 0.6 6.8e-58 196.2 0.0 2.1 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit DUF2167 PF09935.9 KPI42580.1 - 0.0058 15.8 0.5 0.011 15.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2167) APOBEC4 PF18775.1 KPI42580.1 - 0.041 14.0 0.2 0.077 13.2 0.2 1.4 1 0 0 1 1 1 0 APOBEC4 FAD_binding_3 PF01494.19 KPI42581.1 - 1.3e-71 241.7 0.0 1.9e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Polysacc_deac_1 PF01522.21 KPI42582.1 - 1.8e-21 76.3 0.0 2.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPI42582.1 - 1.5e-10 41.1 0.6 3.3e-10 40.0 0.6 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 KPI42582.1 - 1.5e-05 24.4 0.1 2.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 KPI42582.1 - 0.0016 16.9 0.0 0.0021 16.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Rpn9_C PF18261.1 KPI42582.1 - 0.22 11.2 0.3 0.44 10.2 0.3 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix CDP-OH_P_transf PF01066.21 KPI42584.1 - 3.1e-16 59.9 0.1 3.1e-16 59.9 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Response_reg PF00072.24 KPI42585.1 - 2.2e-18 66.5 0.0 8.5e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain cwf21 PF08312.12 KPI42586.1 - 5.8e-12 45.6 16.4 5.8e-12 45.6 16.4 2.0 2 0 0 2 2 2 1 cwf21 domain Ferrochelatase PF00762.19 KPI42587.1 - 2.1e-98 329.3 0.0 2.3e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase RRM_1 PF00076.22 KPI42588.1 - 2.6e-22 78.4 0.5 2e-12 46.7 0.2 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI42588.1 - 0.00084 19.4 0.0 0.11 12.6 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif DUF4890 PF16231.5 KPI42588.1 - 0.055 14.0 0.3 0.21 12.1 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4890) RRM_Rrp7 PF17799.1 KPI42588.1 - 0.069 13.0 0.0 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FoP_duplication PF13865.6 KPI42588.1 - 6.2 7.4 16.6 1.2 9.7 12.0 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 FXMRP1_C_core PF12235.8 KPI42588.1 - 9.8 6.8 14.0 1.4 9.6 6.9 2.5 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal Torus PF16131.5 KPI42589.1 - 4.6e-39 133.5 0.0 1.2e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KPI42589.1 - 7.6e-08 32.1 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KPI42589.1 - 0.00024 21.0 1.1 0.00044 20.2 1.1 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KPI42589.1 - 0.00095 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KPI42589.1 - 0.034 14.1 1.8 0.056 13.4 1.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Alpha_Helical PF18489.1 KPI42589.1 - 0.099 12.8 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 Alpha helical domain zf-CCCH_4 PF18044.1 KPI42589.1 - 1.2 9.0 5.3 1.9 8.4 5.3 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Cu_amine_oxid PF01179.20 KPI42590.1 - 2.6e-149 497.6 0.0 3.1e-149 497.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KPI42590.1 - 4e-20 72.1 0.0 8.2e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KPI42590.1 - 7.8e-11 42.1 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Metal_resist PF13801.6 KPI42591.1 - 0.25 11.5 5.0 0.24 11.6 1.7 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Ferritin_2 PF13668.6 KPI42592.1 - 3.6e-36 124.3 0.8 6e-36 123.6 0.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain HGTP_anticodon PF03129.20 KPI42593.1 - 4e-20 71.8 0.0 4e-20 71.8 0.0 3.2 4 0 0 4 4 4 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KPI42593.1 - 8.3e-08 32.4 0.1 3.2e-07 30.5 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Aminotran_1_2 PF00155.21 KPI42594.1 - 8.4e-80 268.6 0.0 9.5e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hist_deacetyl PF00850.19 KPI42595.1 - 8.1e-55 186.5 0.3 1.7e-40 139.4 0.0 2.3 2 0 0 2 2 2 2 Histone deacetylase domain SCA7 PF08313.12 KPI42595.1 - 8.3e-18 64.1 0.0 1.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 SCA7, zinc-binding domain Clr5 PF14420.6 KPI42595.1 - 1.1e-16 60.8 5.0 1.1e-16 60.8 5.0 2.6 3 0 0 3 3 3 1 Clr5 domain F-box PF00646.33 KPI42596.1 - 4.1e-05 23.3 0.1 8.6e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 KPI42597.1 - 1.6e-17 63.5 34.4 5.9e-12 45.2 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PINIT PF14324.6 KPI42598.1 - 4.7e-26 91.9 1.7 8.9e-23 81.3 1.7 2.8 1 1 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KPI42598.1 - 1.8e-22 78.8 5.7 3e-22 78.1 5.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KPI42598.1 - 3.3e-08 33.1 0.1 7.1e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 KPI42598.1 - 1.3e-05 24.9 1.8 2.6e-05 23.9 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L12_N PF16320.5 KPI42598.1 - 0.39 10.5 0.9 0.82 9.4 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain zf-C3HC4_4 PF15227.6 KPI42598.1 - 0.6 10.3 4.8 1 9.6 4.8 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KPI42598.1 - 1.7 8.6 6.3 2.9 7.8 6.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.19 KPI42600.1 - 1.2e-19 70.8 1.5 1.3e-15 57.5 0.4 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI42600.1 - 1.2e-07 31.6 0.5 1.6e-05 24.7 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI42600.1 - 3.3e-06 27.2 0.0 7.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI42600.1 - 5.2e-06 26.6 0.1 1.7e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI42600.1 - 3.4e-05 23.2 0.0 0.00091 18.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI42600.1 - 0.00048 19.3 1.8 0.00062 19.0 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 KPI42600.1 - 0.0043 16.1 0.0 0.029 13.4 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 KPI42600.1 - 0.012 14.4 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KPI42600.1 - 0.03 14.9 0.1 0.078 13.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI42600.1 - 0.034 13.5 0.0 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KPI42600.1 - 0.038 12.9 0.7 1.2 7.9 0.2 2.7 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 KPI42600.1 - 0.067 12.3 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KPI42600.1 - 0.081 12.2 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KPI42600.1 - 0.19 10.9 1.5 0.38 10.0 1.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3201 PF11447.8 KPI42601.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Sec23_trunk PF04811.15 KPI42602.1 - 2.7e-29 102.5 0.0 2.8e-26 92.6 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KPI42602.1 - 8.6e-25 86.6 0.0 2.7e-24 84.9 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KPI42602.1 - 3.5e-17 62.9 0.0 6.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KPI42602.1 - 2.8e-07 30.3 0.0 6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KPI42602.1 - 5.1e-07 29.6 2.8 1.2e-06 28.4 2.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Abhydrolase_3 PF07859.13 KPI42603.1 - 2e-43 148.7 0.0 3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KPI42603.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 KPI42603.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Mannitol_dh_C PF08125.13 KPI42604.1 - 4.9e-42 144.1 0.0 7.9e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KPI42604.1 - 1.3e-18 67.6 0.4 9.1e-18 64.9 0.1 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 KPI42604.1 - 0.0061 16.5 3.8 0.035 14.0 0.0 3.0 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KPI42604.1 - 0.048 13.3 0.1 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_100 PF12899.7 KPI42604.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase UDPG_MGDP_dh_N PF03721.14 KPI42604.1 - 0.12 11.9 2.9 0.078 12.5 0.5 1.9 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KPI42604.1 - 0.2 12.3 2.0 7.5 7.2 1.5 3.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FMN_bind PF04205.14 KPI42604.1 - 0.21 12.2 0.1 0.21 12.2 0.1 2.4 2 1 0 2 2 2 0 FMN-binding domain DUF724 PF05266.14 KPI42604.1 - 0.33 10.8 2.3 0.87 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UPF0052 PF01933.18 KPI42604.1 - 0.41 9.8 3.4 0.19 10.9 0.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 DUF3486 PF11985.8 KPI42604.1 - 0.61 10.5 4.6 1.2 9.5 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3486) adh_short_C2 PF13561.6 KPI42605.1 - 2.3e-50 171.4 0.1 4.3e-50 170.5 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42605.1 - 1.1e-43 148.9 0.4 1.7e-43 148.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 KPI42605.1 - 3e-32 111.1 0.0 2.9e-31 107.9 0.0 2.3 3 0 0 3 3 3 1 Polysaccharide deacetylase KR PF08659.10 KPI42605.1 - 5.6e-12 45.9 0.2 1.1e-11 45.0 0.2 1.4 1 0 0 1 1 1 1 KR domain Glyco_hydro_57 PF03065.15 KPI42605.1 - 0.013 14.7 0.0 0.072 12.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DUF2334 PF10096.9 KPI42605.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Spore_IV_A PF09547.10 KPI42605.1 - 0.035 13.0 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Sacchrp_dh_NADP PF03435.18 KPI42605.1 - 0.12 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KPI42606.1 - 2.7e-17 63.1 2.4 1.1e-15 57.8 2.4 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI42606.1 - 2.1e-07 30.9 0.2 1.5e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI42606.1 - 4e-07 29.4 0.4 0.0065 15.6 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPI42606.1 - 3.5e-05 23.9 0.2 8.6e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI42606.1 - 5e-05 22.7 0.1 0.025 13.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI42606.1 - 0.00051 20.5 0.6 0.05 14.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI42606.1 - 0.00074 18.8 0.3 0.052 12.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI42606.1 - 0.0043 16.3 0.2 0.0073 15.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KPI42606.1 - 0.0053 15.9 0.1 0.0092 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ACP_syn_III PF08545.10 KPI42606.1 - 0.016 15.0 0.2 0.096 12.5 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ApbA PF02558.16 KPI42606.1 - 0.061 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 KPI42606.1 - 0.066 12.5 0.2 0.69 9.1 0.2 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KPI42606.1 - 0.14 12.1 1.5 14 5.6 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KPI42606.1 - 0.22 10.2 0.3 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_1 PF00232.18 KPI42607.1 - 5.3e-61 206.4 3.0 5.3e-57 193.2 0.2 3.7 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Peptidase_M18 PF02127.15 KPI42609.1 - 9.8e-126 420.0 0.0 8.1e-125 417.0 0.0 2.2 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) FMO-like PF00743.19 KPI42610.1 - 3.3e-11 42.3 0.2 9.8e-11 40.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI42610.1 - 9.9e-08 32.1 0.0 4.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI42610.1 - 2.3e-07 30.4 0.0 1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI42610.1 - 2.4e-07 30.7 0.0 0.00051 19.7 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI42610.1 - 2.7e-07 30.1 0.0 5.7e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI42610.1 - 3.2e-07 29.8 0.1 0.00018 20.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPI42610.1 - 1.8e-05 24.1 0.0 0.00053 19.3 0.0 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 KPI42610.1 - 0.00016 21.7 0.0 0.00049 20.1 0.0 2.0 1 0 0 1 1 1 1 FAD-NAD(P)-binding Phage_F PF02305.17 KPI42610.1 - 0.075 11.8 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) 2-Hacid_dh_C PF02826.19 KPI42610.1 - 0.088 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CUE PF02845.16 KPI42610.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 CUE domain Beta-lactamase PF00144.24 KPI42611.1 - 6.6e-40 137.3 0.0 1.6e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase UCH_1 PF13423.6 KPI42611.1 - 5.7e-12 45.9 0.0 4.8e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KPI42611.1 - 3.9e-10 39.7 0.0 1.9e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ecl1 PF12855.7 KPI42611.1 - 0.65 11.1 4.2 1.8 9.7 4.2 1.7 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins GDI PF00996.18 KPI42612.1 - 5.5e-24 84.5 0.0 1.7e-22 79.5 0.0 2.5 1 1 0 1 1 1 1 GDP dissociation inhibitor Pox_A12 PF04651.13 KPI42613.1 - 0.036 14.1 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A12 protein ORC6 PF05460.13 KPI42613.1 - 6.4 6.0 7.9 12 5.0 7.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF685 PF05085.12 KPI42614.1 - 0.049 12.9 0.2 0.074 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF685) MRP-S25 PF13741.6 KPI42615.1 - 1.8e-71 240.4 0.5 2.3e-71 240.0 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KPI42615.1 - 0.0036 17.5 0.3 1.2 9.4 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial ribosomal protein S23 CdiI_N PF18228.1 KPI42615.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 CdiI N-terminal domain Ldh_1_C PF02866.18 KPI42617.1 - 2.5e-46 157.7 0.0 6.2e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KPI42617.1 - 1.6e-37 128.7 0.1 1e-36 126.1 0.1 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Peptidase_C48 PF02902.19 KPI42617.1 - 1.9e-19 70.4 0.0 4.1e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Apo-VLDL-II PF05418.11 KPI42617.1 - 0.096 13.3 0.4 2.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) Pkinase PF00069.25 KPI42618.1 - 1.5e-57 194.9 0.0 2.2e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42618.1 - 3.5e-23 82.2 0.0 3.3e-22 79.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI42618.1 - 0.001 19.1 0.0 0.0079 16.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPI42618.1 - 0.017 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KPI42618.1 - 0.074 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KPI42618.1 - 0.13 11.5 0.9 1.2 8.4 0.9 2.1 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KPI42618.1 - 0.28 10.2 0.0 0.46 9.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 EMC1_C PF07774.13 KPI42619.1 - 4.9e-72 242.1 0.0 1.4e-71 240.6 0.0 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KPI42619.1 - 1.5e-15 57.5 17.2 1.4e-10 41.1 3.6 4.2 2 2 1 4 4 4 2 PQQ-like domain PQQ PF01011.21 KPI42619.1 - 3.3e-07 29.9 5.4 0.13 12.2 0.0 5.8 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 KPI42619.1 - 0.00021 21.7 13.7 0.016 15.7 0.3 6.2 7 0 0 7 7 7 2 PQQ-like domain Fungal_trans PF04082.18 KPI42620.1 - 6e-20 71.4 0.3 8.8e-20 70.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bot1p PF12298.8 KPI42621.1 - 4.4e-47 160.4 0.1 4.4e-47 160.4 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein SPRY PF00622.28 KPI42623.1 - 0.0051 16.9 0.0 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Es2 PF09751.9 KPI42624.1 - 1.5e-100 338.0 21.7 2e-100 337.6 21.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 DUF1233 PF06806.12 KPI42625.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative excisionase (DUF1233) Iwr1 PF08574.10 KPI42626.1 - 6e-15 56.0 19.2 6e-15 56.0 19.2 3.0 4 1 0 4 4 4 1 Transcription factor Iwr1 Tub_N PF16322.5 KPI42626.1 - 0.01 16.2 4.8 0.01 16.2 4.8 1.6 2 0 0 2 2 2 0 Tubby N-terminal 6PGD PF00393.19 KPI42628.1 - 0.42 9.9 3.4 0.6 9.5 3.4 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain NUT PF12881.7 KPI42628.1 - 0.77 8.1 7.7 0.65 8.4 6.5 1.4 1 1 0 1 1 1 0 NUT protein Glyco_tranf_2_3 PF13641.6 KPI42629.1 - 4.3e-21 75.9 0.1 1.7e-20 73.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI42629.1 - 3.5e-09 36.7 0.0 5.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPI42629.1 - 3.6e-05 23.3 0.0 0.0035 16.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Thioredoxin_8 PF13905.6 KPI42629.1 - 0.097 13.0 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like SKG6 PF08693.10 KPI42630.1 - 0.058 12.8 0.2 0.058 12.8 0.2 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain RIFIN PF02009.16 KPI42630.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rifin Apt1 PF10351.9 KPI42630.1 - 0.13 11.1 4.5 0.14 11.0 4.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 KPI42630.1 - 0.16 11.3 1.5 0.2 11.0 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.9 KPI42630.1 - 0.21 10.7 15.7 0.27 10.4 15.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM51 PF15345.6 KPI42630.1 - 0.24 11.2 5.8 0.54 10.0 0.1 2.3 1 1 1 2 2 2 0 Transmembrane protein 51 Podoplanin PF05808.11 KPI42630.1 - 0.53 10.4 20.4 0.032 14.3 12.5 2.0 1 1 1 2 2 2 0 Podoplanin Macoilin PF09726.9 KPI42630.1 - 0.78 8.2 4.7 0.85 8.1 4.7 1.2 1 0 0 1 1 1 0 Macoilin family PP_M1 PF03012.14 KPI42630.1 - 6.4 6.2 11.8 1.8 8.0 9.0 1.5 2 0 0 2 2 2 0 Phosphoprotein RRM_1 PF00076.22 KPI42631.1 - 0.0032 17.2 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PF2K PF01591.18 KPI42632.1 - 1.5e-61 207.6 0.0 2.1e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KPI42632.1 - 3e-18 66.2 0.1 1.4e-17 64.0 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KPI42632.1 - 0.0023 18.1 0.0 0.44 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF1771 PF08590.10 KPI42632.1 - 0.066 13.6 0.2 0.15 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) RabGAP-TBC PF00566.18 KPI42633.1 - 1.7e-46 158.6 0.9 2.4e-46 158.1 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KPI42633.1 - 0.00017 21.2 0.2 0.03 14.2 0.2 3.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KPI42633.1 - 0.0053 17.2 1.3 0.41 11.1 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KPI42633.1 - 0.023 14.2 0.8 0.75 9.5 1.2 3.2 3 0 0 3 3 3 0 EF hand NDUFA12 PF05071.16 KPI42634.1 - 4.7e-26 91.5 0.1 5.6e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 HAD_2 PF13419.6 KPI42636.1 - 7.6e-25 88.0 0.0 9.8e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI42636.1 - 2e-11 44.6 0.1 1e-07 32.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPI42636.1 - 3.2e-07 30.9 0.0 4.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI42636.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KPI42636.1 - 0.015 15.4 0.1 0.38 10.9 0.1 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 KPI42636.1 - 0.048 13.6 0.1 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PGA_cap PF09587.10 KPI42636.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Transp_cyt_pur PF02133.15 KPI42637.1 - 2.8e-27 95.6 27.5 4.9e-27 94.8 27.5 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.18 KPI42637.1 - 0.00025 20.2 14.8 0.00025 20.2 14.8 2.3 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein OsmC PF02566.19 KPI42638.1 - 1.2e-15 57.8 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Fungal_trans_2 PF11951.8 KPI42640.1 - 0.0028 16.5 0.2 0.0043 15.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 KPI42641.1 - 9.5e-15 54.3 3.1 1.6e-10 40.7 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein Oxidored_FMN PF00724.20 KPI42642.1 - 1.3e-73 248.3 0.0 1.1e-67 228.7 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family SCIMP PF15050.6 KPI42645.1 - 0.12 12.8 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 SCIMP protein EAP30 PF04157.16 KPI42646.1 - 2.1e-41 141.8 0.0 3e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KPI42646.1 - 6.3e-22 77.6 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KPI42646.1 - 6.9e-17 60.6 0.9 6.9e-17 60.6 0.9 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KPI42646.1 - 0.00013 21.9 3.8 0.037 14.1 0.3 2.6 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Ribosomal_L50 PF10501.9 KPI42646.1 - 0.00036 20.6 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal subunit 39S zf-RanBP PF00641.18 KPI42646.1 - 0.0066 15.7 6.5 0.013 14.8 0.9 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 KPI42646.1 - 0.024 14.7 0.9 0.024 14.7 0.9 1.9 2 0 0 2 2 2 0 Double zinc ribbon RIFIN PF02009.16 KPI42647.1 - 0.0013 18.7 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Rifin GAPT PF11770.8 KPI42647.1 - 0.04 13.8 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Hum_adeno_E3A PF05393.11 KPI42647.1 - 0.069 13.1 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein SCIMP PF15050.6 KPI42647.1 - 0.07 13.6 0.0 0.093 13.2 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein EMP70 PF02990.16 KPI42648.1 - 2.8e-183 610.3 0.0 3.4e-183 610.0 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Chitin_bind_1 PF00187.19 KPI42649.1 - 2.8e-07 30.9 38.0 0.0018 18.7 18.6 2.5 2 0 0 2 2 2 2 Chitin recognition protein Glycophorin_A PF01102.18 KPI42649.1 - 0.13 12.5 1.4 0.22 11.8 0.3 1.8 1 1 1 2 2 2 0 Glycophorin A LapA_dom PF06305.11 KPI42649.1 - 0.2 11.5 0.6 0.35 10.7 0.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HMG_box PF00505.19 KPI42651.1 - 1.6e-24 86.1 1.2 2.5e-24 85.5 1.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPI42651.1 - 4.4e-18 65.6 1.4 7.7e-18 64.9 1.4 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KPI42651.1 - 0.004 17.7 0.1 0.004 17.7 0.1 2.3 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 KPI42651.1 - 0.0083 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 KPI42651.1 - 0.017 15.1 0.4 0.017 15.1 0.4 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box 5 HET PF06985.11 KPI42652.1 - 6.8e-30 104.3 0.7 4.4e-29 101.7 0.4 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CBM32 PF18344.1 KPI42652.1 - 0.009 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate binding module family 32 AAA_11 PF13086.6 KPI42653.1 - 8.1e-06 25.8 0.0 4.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KPI42653.1 - 0.038 13.6 0.0 0.091 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI42653.1 - 0.15 11.7 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain FolB PF02152.18 KPI42654.1 - 3.7e-16 59.6 0.0 1.2e-07 32.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Hat1_N PF10394.9 KPI42654.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.5 1 1 1 2 2 2 0 Histone acetyl transferase HAT1 N-terminus MFS_1 PF07690.16 KPI42655.1 - 1.4e-40 139.3 38.8 1.4e-40 139.3 38.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Clr5 PF14420.6 KPI42656.1 - 5.9e-12 45.6 6.2 6.1e-11 42.4 1.1 3.2 3 1 0 3 3 3 1 Clr5 domain CpeT PF06206.11 KPI42656.1 - 0.014 15.4 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 CpeT/CpcT family (DUF1001) DUF123 PF01986.16 KPI42656.1 - 0.053 14.0 0.9 11 6.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF123 Nif11 PF07862.11 KPI42656.1 - 0.078 13.3 0.2 5.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Nif11 domain zf-C3HC4_4 PF15227.6 KPI42656.1 - 0.17 12.1 1.2 0.36 11.0 1.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ubiquitin PF00240.23 KPI42657.1 - 8.1e-19 67.1 0.0 1.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KPI42657.1 - 3.7e-07 29.9 0.0 1.3e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KPI42657.1 - 9.8e-07 28.5 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KPI42657.1 - 4.3e-06 26.8 0.0 7.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KPI42657.1 - 0.0023 18.5 0.0 0.0046 17.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 KPI42657.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 KPI42657.1 - 0.031 14.9 0.0 0.084 13.6 0.0 1.8 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Blt1 PF12754.7 KPI42657.1 - 0.042 14.2 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain STI1 PF17830.1 KPI42657.1 - 0.37 10.7 16.6 0.19 11.7 2.7 3.8 3 0 0 3 3 3 0 STI1 domain GerD PF17898.1 KPI42657.1 - 1 9.3 3.3 3.7 7.5 0.2 2.3 1 1 1 2 2 2 0 Spore germination GerD central core domain Sugar_tr PF00083.24 KPI42658.1 - 2.6e-90 303.4 26.5 3e-90 303.3 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42658.1 - 5.8e-19 68.2 36.5 3.5e-15 55.8 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5464 PF17552.2 KPI42658.1 - 0.11 12.7 5.3 0.11 12.7 2.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5464) SLAC1 PF03595.17 KPI42659.1 - 1.4e-71 241.4 33.3 1.7e-71 241.2 33.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SBDS PF01172.18 KPI42660.1 - 2.3e-26 91.7 0.2 2.7e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DEAD PF00270.29 KPI42662.1 - 2.1e-26 92.8 0.4 3.7e-25 88.7 0.4 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI42662.1 - 3.4e-20 72.5 0.6 2.5e-19 69.7 0.2 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI42662.1 - 2.2e-06 27.8 0.1 7.9e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KPI42662.1 - 0.083 11.7 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer RNA_pol_N PF01194.17 KPI42663.1 - 4.7e-29 100.5 2.6 5.6e-29 100.2 2.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit COesterase PF00135.28 KPI42664.1 - 2.9e-54 184.8 0.0 5e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF3425 PF11905.8 KPI42664.1 - 2.7e-11 43.5 0.1 5.3e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_3 PF07859.13 KPI42664.1 - 1e-07 32.1 3.5 0.0022 17.9 0.1 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold bZIP_1 PF00170.21 KPI42664.1 - 0.00046 20.2 2.6 0.00046 20.2 2.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor Esterase PF00756.20 KPI42664.1 - 0.0046 16.6 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Putative esterase DUF2525 PF10733.9 KPI42664.1 - 0.046 14.0 0.6 7.3 6.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) bZIP_2 PF07716.15 KPI42664.1 - 0.069 13.2 4.2 0.15 12.2 4.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Tektin PF03148.14 KPI42664.1 - 0.25 10.1 2.1 0.37 9.5 2.1 1.1 1 0 0 1 1 1 0 Tektin family Abhydrolase_6 PF12697.7 KPI42664.1 - 2.1 8.9 14.5 0.043 14.4 5.9 2.5 2 1 1 3 3 3 0 Alpha/beta hydrolase family Peptidase_M19 PF01244.21 KPI42665.1 - 5.4e-96 321.5 0.0 6.5e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Cation_efflux PF01545.21 KPI42666.1 - 7.2e-20 71.6 6.4 9e-20 71.2 6.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPI42666.1 - 1.8e-10 40.8 0.5 4e-10 39.7 0.5 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MIG-14_Wnt-bd PF06664.12 KPI42666.1 - 0.46 9.7 5.9 0.46 9.6 4.5 1.6 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion MFS_1 PF07690.16 KPI42667.1 - 1.3e-38 132.8 42.3 4.8e-38 131.0 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI42667.1 - 2.5e-12 46.4 12.9 2.5e-12 46.4 12.9 3.6 2 2 1 4 4 4 1 Sugar (and other) transporter PTR2 PF00854.21 KPI42667.1 - 0.01 14.7 3.5 0.016 14.1 3.0 1.6 1 1 0 1 1 1 0 POT family SBD_N PF07005.11 KPI42668.1 - 2.7e-63 213.8 0.1 1.8e-62 211.1 0.0 1.9 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KPI42668.1 - 3.7e-39 135.0 0.2 7.9e-39 133.9 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain MFS_1 PF07690.16 KPI42669.1 - 7.4e-20 71.2 68.6 3e-14 52.7 37.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.22 KPI42670.1 - 9.1e-32 110.4 0.1 6.6e-31 107.6 0.1 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Aconitase PF00330.20 KPI42671.1 - 9.1e-163 542.5 0.0 1.1e-162 542.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPI42671.1 - 3.4e-40 137.4 0.0 6.4e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2156 PF09924.9 KPI42672.1 - 6.2e-29 100.9 0.0 9.1e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Pkinase PF00069.25 KPI42673.1 - 1.4e-36 126.3 0.0 1.9e-34 119.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain XPC-binding PF09280.11 KPI42673.1 - 9.1e-15 54.1 1.2 1.9e-14 53.1 1.2 1.6 1 0 0 1 1 1 1 XPC-binding domain EF-hand_4 PF12763.7 KPI42673.1 - 6e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Pkinase_Tyr PF07714.17 KPI42673.1 - 1.1e-11 44.5 0.0 5.9e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase UBA PF00627.31 KPI42673.1 - 6.9e-11 41.8 0.1 1.4e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_9 PF14658.6 KPI42673.1 - 0.0084 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KPI42673.1 - 0.013 15.0 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KPI42673.1 - 0.034 14.6 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair UBA_3 PF09288.10 KPI42673.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain MMS1_N PF10433.9 KPI42674.1 - 2.6e-152 507.9 0.0 1.5e-151 505.4 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KPI42674.1 - 1.4e-97 326.9 0.0 1.2e-96 323.9 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KPI42674.1 - 0.055 13.8 0.0 3.1 8.2 0.0 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KPI42674.1 - 0.15 12.0 0.2 41 4.2 0.0 3.8 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal CoA_transf_3 PF02515.17 KPI42675.1 - 6.5e-111 371.0 0.0 7.4e-111 370.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF1932 PF09130.11 KPI42675.1 - 0.11 12.5 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) DLH PF01738.18 KPI42676.1 - 6.8e-14 51.9 0.7 8.9e-09 35.2 3.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family ECM11 PF15463.6 KPI42677.1 - 0.0003 21.4 13.1 0.2 12.2 0.1 4.2 3 1 1 4 4 4 3 Extracellular mutant protein 11 RNA_lig_T4_1 PF09511.10 KPI42677.1 - 0.13 12.1 1.0 68 3.2 0.0 3.3 4 0 0 4 4 4 0 RNA ligase DUF4124 PF13511.6 KPI42677.1 - 1.9 8.9 18.2 15 6.0 0.6 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4124) AMP-binding PF00501.28 KPI42678.1 - 3.2e-60 203.9 0.2 1.1e-24 86.9 0.0 4.5 3 1 1 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 KPI42678.1 - 2e-10 41.5 0.1 2e-10 41.5 0.1 3.2 3 0 0 3 3 3 1 DMAP1-binding Domain GvpG PF05120.12 KPI42678.1 - 0.026 14.5 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 Gas vesicle protein G RNA_pol_I_TF PF04090.12 KPI42679.1 - 2.2e-13 50.2 0.0 5.5e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.6 KPI42679.1 - 0.32 11.7 3.5 12 6.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Tannase PF07519.11 KPI42681.1 - 2.5e-91 307.0 0.2 2.4e-67 227.9 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KPI42681.1 - 0.00019 21.2 0.7 0.0007 19.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI42681.1 - 0.00065 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Mis12 PF05859.12 KPI42682.1 - 1.3e-43 148.3 1.0 2.6e-43 147.3 0.1 1.8 2 0 0 2 2 2 1 Mis12 protein DUF1843 PF08898.10 KPI42682.1 - 0.012 16.1 2.6 0.034 14.6 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF3261 PF11659.8 KPI42682.1 - 0.019 14.9 0.4 0.031 14.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) TnsE_C PF18623.1 KPI42682.1 - 0.057 13.3 0.1 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 TnsE C-terminal domain Cgr1 PF03879.14 KPI42682.1 - 0.09 13.2 0.4 0.09 13.2 0.4 1.9 2 0 0 2 2 2 0 Cgr1 family DUF4407 PF14362.6 KPI42682.1 - 0.28 10.5 5.3 0.37 10.1 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) M PF02370.16 KPI42682.1 - 3.6 8.5 6.9 28 5.7 1.5 3.7 3 0 0 3 3 3 0 M protein repeat COQ9 PF08511.11 KPI42683.1 - 5e-31 106.3 1.1 7.6e-31 105.7 0.1 1.8 2 0 0 2 2 2 1 COQ9 Ints3 PF10189.9 KPI42684.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 3 Na_H_Exchanger PF00999.21 KPI42685.1 - 1.1e-34 119.8 18.4 1.7e-34 119.3 18.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KPI42685.1 - 0.023 14.8 0.7 0.12 12.5 0.3 2.4 2 0 0 2 2 2 0 YrhC-like protein RTA1 PF04479.13 KPI42686.1 - 2.6e-37 128.5 4.2 2.6e-37 128.5 4.2 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF308 PF03729.13 KPI42686.1 - 0.00091 19.5 2.7 0.00091 19.5 2.7 2.7 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) DUF4131 PF13567.6 KPI42686.1 - 1.7 8.3 8.2 0.82 9.3 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.8 KPI42687.1 - 2.8e-06 26.4 0.0 4.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF963 PF06131.11 KPI42687.1 - 0.054 12.9 2.3 0.11 11.9 2.3 1.4 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Fungal_trans PF04082.18 KPI42688.1 - 6.7e-17 61.4 2.3 1e-15 57.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KPI42688.1 - 0.00059 18.8 0.1 0.00079 18.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_6 PF13405.6 KPI42689.1 - 0.0016 18.2 0.1 0.0074 16.1 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KPI42689.1 - 0.002 18.6 0.2 0.0044 17.4 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KPI42689.1 - 0.002 17.5 0.3 0.0063 16.0 0.3 1.9 1 0 0 1 1 1 1 EF hand P22_AR_C PF10548.9 KPI42689.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 P22AR C-terminal domain adh_short_C2 PF13561.6 KPI42690.1 - 1.6e-43 148.9 0.7 6.9e-43 146.9 0.7 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42690.1 - 7.4e-36 123.4 0.3 3.9e-35 121.1 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KPI42690.1 - 7.3e-08 32.2 0.0 5.5e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI42690.1 - 1.7e-05 24.0 0.1 2.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KPI42690.1 - 2e-05 24.6 1.6 0.00047 20.1 0.5 2.9 2 1 0 2 2 2 1 KR domain NAD_binding_7 PF13241.6 KPI42690.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F-box-like PF12937.7 KPI42691.1 - 7.6e-08 32.1 0.2 2.3e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KPI42691.1 - 0.0002 21.2 0.6 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 1 F-box domain bZIP_2 PF07716.15 KPI42692.1 - 0.00081 19.4 7.3 0.0013 18.8 7.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KPI42692.1 - 0.051 13.7 5.1 0.082 13.0 5.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor UDPG_MGDP_dh PF00984.19 KPI42693.1 - 1.2e-19 70.3 0.0 4.9e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KPI42693.1 - 1.3e-17 64.0 0.6 2.1e-17 63.3 0.6 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KPI42693.1 - 0.00019 21.6 0.1 0.0054 17.0 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 KPI42693.1 - 0.00028 21.1 0.2 0.00081 19.6 0.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KPI42693.1 - 0.0024 18.3 0.0 0.007 16.8 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 KPI42693.1 - 0.018 14.9 0.1 0.054 13.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KPI42693.1 - 0.029 15.2 0.2 0.18 12.6 0.0 2.3 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CLAG PF03805.13 KPI42693.1 - 0.037 11.6 0.1 0.051 11.2 0.1 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein RNase_II_C_S1 PF18614.1 KPI42693.1 - 0.064 13.2 1.1 4.3 7.4 0.1 2.4 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain YqgC PF17430.2 KPI42693.1 - 0.49 10.5 5.2 55 3.9 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized YqgC-like Form_Nir_trans PF01226.17 KPI42694.1 - 8.4e-71 238.0 19.8 9.6e-71 237.9 19.8 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF3341 PF11821.8 KPI42694.1 - 0.03 14.0 3.1 0.061 13.0 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) Abhydrolase_1 PF00561.20 KPI42696.1 - 2.3e-25 89.7 0.0 4.7e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI42696.1 - 1.6e-10 40.7 0.0 2.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI42696.1 - 2.4e-08 34.8 0.2 2.9e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KPI42696.1 - 0.00088 18.9 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 KPI42696.1 - 0.046 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S28 PF05577.12 KPI42696.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 BTB PF00651.31 KPI42697.1 - 7.9e-10 39.0 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zinc_ribbon_2 PF13240.6 KPI42697.1 - 0.028 14.1 0.6 0.075 12.8 0.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DUF745 PF05335.13 KPI42697.1 - 0.054 13.2 0.6 0.089 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2039 PF10217.9 KPI42697.1 - 0.057 13.8 3.6 0.094 13.1 3.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.7 KPI42697.1 - 0.059 13.4 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon DHR10 PF18595.1 KPI42697.1 - 0.069 13.2 2.1 0.14 12.2 2.0 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain UTP15_C PF09384.10 KPI42698.1 - 1.2e-42 145.1 0.0 1.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KPI42698.1 - 1.7e-18 66.6 3.9 0.00044 21.0 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI42698.1 - 4.6e-08 33.2 0.2 0.0014 18.9 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KPI42698.1 - 0.015 14.6 0.0 1.6 7.9 0.0 2.8 3 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KPI42698.1 - 0.097 11.6 0.0 7.7 5.4 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_transf_17 PF04724.13 KPI42700.1 - 1.4e-38 132.8 0.0 2.1e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 OapA_N PF08525.11 KPI42700.1 - 5.4 7.1 6.6 12 6.0 6.6 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Bystin PF05291.11 KPI42702.1 - 1.3e-123 412.0 0.0 1.7e-123 411.6 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF3237 PF11578.8 KPI42703.1 - 1.6e-24 86.4 0.5 7.2e-20 71.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) NAD_binding_6 PF08030.12 KPI42704.1 - 8.8e-23 81.1 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI42704.1 - 1.7e-21 76.4 0.0 3.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KPI42704.1 - 6.9e-20 71.4 8.9 6.9e-20 71.4 8.9 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KPI42704.1 - 0.055 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DPPIV_N PF00930.21 KPI42705.1 - 1.8e-102 342.8 4.2 2.6e-102 342.2 4.2 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KPI42705.1 - 5.2e-33 114.3 0.5 8.4e-33 113.6 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_17_28 PF03424.14 KPI42705.1 - 0.087 12.5 0.4 0.45 10.2 0.1 2.2 3 0 0 3 3 3 0 Carbohydrate binding domain (family 17/28) ADH_zinc_N PF00107.26 KPI42707.1 - 4.8e-20 71.8 0.1 1e-19 70.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI42707.1 - 5.9e-19 68.0 3.7 2e-17 63.1 3.7 2.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI42707.1 - 0.0005 19.6 0.4 0.00087 18.8 0.4 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI42707.1 - 0.013 16.6 0.0 0.023 15.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KPI42707.1 - 0.022 14.0 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KPI42707.1 - 0.045 13.8 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KPI42707.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DASH_Duo1 PF08651.10 KPI42708.1 - 1.1e-25 89.2 0.4 2e-25 88.4 0.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 KPI42708.1 - 0.074 13.5 6.0 0.14 12.6 6.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 POR PF01558.18 KPI42709.1 - 0.15 12.2 0.0 4.7 7.2 0.0 2.4 1 1 1 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Peptidase_S30 PF01577.16 KPI42709.1 - 3.9 7.0 6.7 5.6 6.5 2.6 2.1 2 0 0 2 2 2 0 Potyvirus P1 protease Bromodomain PF00439.25 KPI42710.1 - 7.1e-25 86.9 0.5 1.5e-24 85.8 0.5 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KPI42710.1 - 4.7e-08 33.3 0.0 8.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI42710.1 - 1.7e-06 28.0 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI42710.1 - 0.0003 21.2 0.1 0.00052 20.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_47 PF01532.20 KPI42711.1 - 8.1e-160 532.7 0.0 1e-159 532.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HSP70 PF00012.20 KPI42713.1 - 1.8e-11 43.0 0.6 4.9e-11 41.6 0.6 1.6 1 1 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.25 KPI42713.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycoprotease family ECF_trnsprt PF12822.7 KPI42714.1 - 0.59 10.2 12.4 0.15 12.2 0.4 2.3 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Mad3_BUB1_I PF08311.12 KPI42716.1 - 1e-41 141.8 1.3 2e-41 140.8 1.3 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KPI42716.1 - 1.2e-08 35.0 0.0 6.1e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KPI42716.1 - 1.6e-08 34.3 0.0 1.6e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42716.1 - 2.1e-05 23.9 0.0 6.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KPI42716.1 - 0.00015 21.9 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Filament PF00038.21 KPI42717.1 - 0.017 14.8 13.0 0.016 14.8 10.8 1.7 1 1 1 2 2 2 0 Intermediate filament protein DUF812 PF05667.11 KPI42717.1 - 0.023 13.6 6.8 0.033 13.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KxDL PF10241.9 KPI42717.1 - 0.024 14.9 1.2 0.024 14.9 1.2 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein Cluap1 PF10234.9 KPI42717.1 - 0.033 13.6 10.6 0.13 11.7 0.2 2.5 1 1 0 2 2 2 0 Clusterin-associated protein-1 DASH_Hsk3 PF08227.11 KPI42717.1 - 0.051 13.9 2.9 0.094 13.1 0.9 2.6 2 0 0 2 2 1 0 DASH complex subunit Hsk3 like SOGA PF11365.8 KPI42717.1 - 0.064 14.4 5.1 3 9.0 1.6 2.7 1 1 1 2 2 2 0 Protein SOGA Seryl_tRNA_N PF02403.22 KPI42717.1 - 0.08 13.2 5.8 0.075 13.3 1.8 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KPI42717.1 - 0.11 11.4 16.2 0.43 9.4 1.4 3.0 2 1 0 3 3 3 0 Spc7 kinetochore protein V-SNARE PF05008.15 KPI42717.1 - 0.14 12.6 6.0 0.48 10.8 5.4 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc42p PF11544.8 KPI42717.1 - 0.14 12.1 4.1 0.31 11.1 2.3 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p Syntaxin-6_N PF09177.11 KPI42717.1 - 0.17 12.5 5.7 1.7 9.3 0.5 2.9 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Peptidase_M32 PF02074.15 KPI42717.1 - 0.19 10.5 8.1 0.079 11.7 0.9 2.0 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Syntaxin_2 PF14523.6 KPI42717.1 - 1.4 9.4 4.9 1.7 9.1 0.0 2.8 2 1 1 3 3 3 0 Syntaxin-like protein GAS PF13851.6 KPI42717.1 - 2.3 7.5 12.9 0.13 11.6 4.6 2.5 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding FeoB_Cyto PF17910.1 KPI42717.1 - 2.4 8.8 5.5 2.6 8.6 3.0 2.6 2 1 0 2 2 2 0 FeoB cytosolic helical domain GIT_CC PF16559.5 KPI42717.1 - 2.5 8.0 8.7 5 7.1 0.8 3.6 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Enkurin PF13864.6 KPI42717.1 - 2.6 8.5 11.7 0.59 10.6 5.1 2.7 3 0 0 3 3 3 0 Calmodulin-binding DUF1154 PF06631.11 KPI42717.1 - 3.4 7.8 6.7 5.8 7.0 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Uso1_p115_C PF04871.13 KPI42717.1 - 3.8 7.9 13.6 2.5 8.5 5.6 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Com_YlbF PF06133.11 KPI42717.1 - 5 7.8 10.1 34 5.1 0.1 3.0 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF3450 PF11932.8 KPI42717.1 - 7.7 5.7 16.6 0.64 9.3 2.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) zf-C2H2_jaz PF12171.8 KPI42718.1 - 0.0027 17.9 0.0 0.0075 16.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding UDPGP PF01704.18 KPI42719.1 - 1.5e-07 30.5 0.0 2.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ThiS PF02597.20 KPI42719.1 - 3.4e-06 27.6 0.2 0.022 15.4 0.0 2.5 2 0 0 2 2 2 2 ThiS family MOZ_SAS PF01853.18 KPI42720.1 - 8.9e-71 237.2 0.1 2.7e-70 235.7 0.1 1.8 2 0 0 2 2 2 1 MOZ/SAS family adh_short_C2 PF13561.6 KPI42720.1 - 6.3e-40 137.2 0.0 3e-39 135.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42720.1 - 7.1e-40 136.6 0.0 5.9e-39 133.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase zf-MYST PF17772.1 KPI42720.1 - 1.3e-16 60.0 3.6 2.8e-16 58.8 3.6 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain KR PF08659.10 KPI42720.1 - 4.1e-06 26.8 0.0 8.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain PHD PF00628.29 KPI42720.1 - 0.00013 21.8 6.0 0.00013 21.8 6.0 2.1 2 0 0 2 2 2 1 PHD-finger zf-Sec23_Sec24 PF04810.15 KPI42720.1 - 0.014 15.4 0.1 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Prok-RING_1 PF14446.6 KPI42720.1 - 0.058 13.3 3.0 0.16 12.0 3.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 KPI42720.1 - 0.15 12.2 9.9 0.17 12.0 7.1 2.7 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KPI42720.1 - 0.33 10.9 5.9 0.097 12.6 0.3 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sugar_tr PF00083.24 KPI42722.1 - 7e-76 255.9 16.9 1.3e-60 205.6 5.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42722.1 - 2.4e-22 79.4 37.8 1.9e-12 46.8 6.2 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily adh_short_C2 PF13561.6 KPI42723.1 - 1e-37 129.9 1.7 3.3e-30 105.4 1.9 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42723.1 - 3.5e-35 121.3 0.7 1.7e-34 119.0 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42723.1 - 2.8e-06 27.4 0.1 5.1e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KPI42723.1 - 0.0057 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KPI42723.1 - 0.034 13.5 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KPI42723.1 - 0.18 11.9 0.4 0.33 11.0 0.4 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Chitin_synth_2 PF03142.15 KPI42724.1 - 7e-32 110.7 5.7 1.4e-19 70.2 3.8 2.1 2 0 0 2 2 2 2 Chitin synthase Sugar_tr PF00083.24 KPI42725.1 - 4.5e-70 236.8 14.0 5.2e-70 236.6 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42725.1 - 5.8e-17 61.6 26.9 1.6e-16 60.2 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DBR1 PF05011.13 KPI42726.1 - 4.3e-27 95.2 0.1 7.1e-26 91.3 0.0 2.1 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KPI42726.1 - 0.00039 21.0 0.6 0.0007 20.1 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pribosyl_synth PF14572.6 KPI42727.1 - 2.3e-43 148.4 2.2 6.1e-36 124.2 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KPI42727.1 - 2.4e-32 111.3 0.0 8.1e-32 109.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KPI42727.1 - 2.4e-14 53.2 0.6 4.5e-14 52.3 0.6 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KPI42727.1 - 0.011 15.2 0.2 0.017 14.5 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Abhydrolase_3 PF07859.13 KPI42728.1 - 2.5e-18 66.7 0.0 3.4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPI42728.1 - 2.6e-10 39.7 0.0 6.4e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KPI42728.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 KPI42728.1 - 0.21 11.0 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Peptidase_S10 PF00450.22 KPI42729.1 - 4.2e-71 240.6 0.4 5.8e-71 240.1 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 KPI42731.1 - 7.8e-29 100.7 23.8 7.8e-29 100.7 23.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI42731.1 - 3.2e-08 32.9 11.3 3.2e-08 32.9 11.3 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_76 PF03663.14 KPI42732.1 - 1.5e-131 439.3 14.4 1.7e-131 439.1 14.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KPI42732.1 - 0.03 13.4 7.4 0.17 10.9 7.4 2.0 1 1 0 1 1 1 0 Glycosyl Hydrolase Family 88 NAD_binding_8 PF13450.6 KPI42733.1 - 6.8e-08 32.6 0.1 1.5e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI42733.1 - 3.7e-07 29.8 0.0 7.4e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KPI42733.1 - 2.9e-06 26.8 0.4 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI42733.1 - 0.0068 15.7 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPI42733.1 - 0.0072 15.6 0.3 0.015 14.6 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI42733.1 - 0.0099 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPI42733.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KPI42733.1 - 0.062 12.6 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI42733.1 - 0.067 13.2 0.1 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KPI42733.1 - 0.088 11.5 0.2 0.18 10.4 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KPI42733.1 - 0.11 11.5 0.2 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 KPI42733.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Sec1 PF00995.23 KPI42734.1 - 8.2e-124 414.9 0.0 9.4e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2813 PF11398.8 KPI42734.1 - 0.0042 16.4 0.1 0.0086 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) UAE_UbL PF14732.6 KPI42734.1 - 0.11 13.1 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ABM PF03992.16 KPI42735.1 - 0.0053 16.9 0.2 0.0085 16.2 0.2 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Drc1-Sld2 PF11719.8 KPI42736.1 - 1.2e-64 219.5 40.4 6.4e-62 210.6 40.4 2.1 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF1180 PF06679.12 KPI42737.1 - 2.4 8.5 6.6 3.1 8.2 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Fungal_trans PF04082.18 KPI42738.1 - 2.3e-13 49.8 0.3 3e-13 49.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI42739.1 - 3.3e-28 98.6 31.0 1.5e-27 96.5 32.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 KPI42740.1 - 1.5e-38 132.0 4.0 1.5e-38 132.0 4.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 LysM PF01476.20 KPI42740.1 - 5.4e-28 96.8 4.5 5e-06 26.5 0.0 5.4 5 0 0 5 5 5 5 LysM domain Acyl_transf_3 PF01757.22 KPI42742.1 - 3.2e-16 59.3 29.3 3.1e-14 52.8 29.3 2.7 1 1 0 1 1 1 1 Acyltransferase family Spt20 PF12090.8 KPI42743.1 - 3.7e-42 144.5 0.0 3.7e-42 144.5 0.0 7.0 3 2 1 4 4 4 1 Spt20 family FA_hydroxylase PF04116.13 KPI42744.1 - 2e-17 63.8 1.5 2e-17 63.8 1.5 2.4 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily adh_short_C2 PF13561.6 KPI42747.1 - 4.1e-64 216.3 0.6 6.1e-64 215.8 0.6 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42747.1 - 1.1e-47 162.1 0.2 1.5e-47 161.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42747.1 - 5.1e-12 46.1 1.1 1.4e-11 44.6 1.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI42747.1 - 2.4e-06 26.9 0.1 4.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI42747.1 - 0.0058 16.1 0.8 0.049 13.1 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KPI42747.1 - 0.01 15.9 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_16 PF10294.9 KPI42748.1 - 1.2e-22 80.5 0.0 1.8e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KPI42748.1 - 4.5e-08 33.1 0.0 1.1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI42748.1 - 0.0029 18.3 0.0 0.016 15.9 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain PrmA PF06325.13 KPI42748.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.5 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPI42748.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain TauD PF02668.16 KPI42749.1 - 1.1e-33 117.1 0.1 1.4e-33 116.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KPI42749.1 - 0.0057 15.8 0.0 0.011 14.8 0.0 1.4 2 0 0 2 2 2 1 CsiD DUF1573 PF07610.11 KPI42751.1 - 0.02 14.9 0.5 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) PDEase_I PF00233.19 KPI42752.1 - 1.4e-66 224.6 0.0 2.7e-66 223.7 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Amidase PF01425.21 KPI42753.1 - 1.2e-87 294.8 0.0 1.8e-87 294.2 0.0 1.2 1 0 0 1 1 1 1 Amidase DBB PF14545.6 KPI42753.1 - 0.17 11.8 0.0 1.5 8.8 0.0 2.4 3 0 0 3 3 3 0 Dof, BCAP, and BANK (DBB) motif, DUF3328 PF11807.8 KPI42755.1 - 2.3e-52 178.0 0.0 2.9e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WD40 PF00400.32 KPI42756.1 - 0.0002 22.1 6.9 0.11 13.4 0.2 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI42756.1 - 0.0081 16.4 0.7 2.3 8.6 0.0 4.3 3 3 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Polyketide_cyc PF03364.20 KPI42756.1 - 0.082 13.1 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Sigma70_ECF PF07638.11 KPI42756.1 - 0.15 11.9 2.4 0.41 10.5 2.4 1.7 1 0 0 1 1 1 0 ECF sigma factor Sulfotransfer_3 PF13469.6 KPI42757.1 - 0.00025 21.5 0.3 1.9 8.8 0.0 3.4 4 0 0 4 4 4 2 Sulfotransferase family FoP_duplication PF13865.6 KPI42757.1 - 5.3 7.7 6.4 9.6 6.8 2.7 2.8 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DUF3419 PF11899.8 KPI42758.1 - 3.5e-151 503.8 0.0 5e-151 503.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 KPI42758.1 - 3.4e-10 40.5 0.0 1.2e-09 38.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI42758.1 - 4.8e-10 39.9 0.0 3e-09 37.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI42758.1 - 1.2e-09 38.2 0.0 1.8e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI42758.1 - 8.9e-09 36.0 0.0 1.1e-07 32.5 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI42758.1 - 3.1e-08 33.2 0.0 7.1e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KPI42758.1 - 2.6e-06 27.3 0.0 7.7e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KPI42758.1 - 1.9e-05 24.5 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AMP-binding PF00501.28 KPI42759.1 - 2.7e-29 102.0 0.1 1.6e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Thiolase_N PF00108.23 KPI42760.1 - 2.2e-73 246.8 0.6 2.8e-73 246.5 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI42760.1 - 8.1e-39 132.1 0.2 2.6e-38 130.4 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPI42760.1 - 0.045 13.3 2.7 0.094 12.3 2.1 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPI42760.1 - 0.12 12.3 1.7 3.6 7.5 0.3 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Tannase PF07519.11 KPI42761.1 - 6.8e-109 364.9 0.2 8.3e-109 364.6 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KPI42761.1 - 0.0014 18.0 0.1 0.0031 16.8 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF5633 PF18656.1 KPI42761.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5633) polyprenyl_synt PF00348.17 KPI42763.1 - 1e-69 234.5 0.0 2.7e-69 233.1 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase AMMECR1 PF01871.17 KPI42763.1 - 2.3e-38 131.4 0.0 4.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 HEPPP_synt_1 PF07307.11 KPI42763.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 PRIMA1 PF16101.5 KPI42764.1 - 0.0019 18.2 2.3 0.003 17.6 2.2 1.4 1 1 0 1 1 1 1 Proline-rich membrane anchor 1 Lipocalin_5 PF13924.6 KPI42765.1 - 2.5e-25 88.9 0.2 2.9e-25 88.7 0.2 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Aldo_ket_red PF00248.21 KPI42766.1 - 1.1e-43 149.6 0.0 2.3e-41 141.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CENP-X PF09415.10 KPI42767.1 - 8.3e-19 67.7 0.0 1.9e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Dicty_REP PF05086.12 KPI42767.1 - 0.077 11.0 14.8 0.09 10.8 14.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med13_C PF06333.12 KPI42767.1 - 0.39 9.9 9.1 0.48 9.6 9.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain AAR2 PF05282.11 KPI42767.1 - 1 8.7 4.5 1.4 8.2 4.5 1.3 1 0 0 1 1 1 0 AAR2 protein FAM60A PF15396.6 KPI42767.1 - 1.1 9.3 9.3 1.4 8.9 9.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SPX PF03105.19 KPI42767.1 - 1.2 9.0 16.4 1.4 8.7 16.4 1.2 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 KPI42767.1 - 1.5 7.5 9.2 1.6 7.4 9.2 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 KPI42767.1 - 2.1 8.2 8.7 2.9 7.8 8.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 KPI42767.1 - 4.8 4.2 5.6 5 4.1 5.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ORC6 PF05460.13 KPI42767.1 - 8.8 5.5 17.1 12 5.0 17.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NYN PF01936.18 KPI42768.1 - 4.6e-05 23.9 0.0 0.0002 21.9 0.0 1.9 1 1 0 1 1 1 1 NYN domain MFS_1 PF07690.16 KPI42769.1 - 1.1e-31 110.0 41.7 8.1e-28 97.3 33.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI42769.1 - 2.8e-06 26.1 2.9 4.7e-06 25.3 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPPK_C PF12555.8 KPI42769.1 - 0.94 9.6 6.1 0.79 9.8 2.0 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Abhydrolase_6 PF12697.7 KPI42770.1 - 2.8e-09 37.9 7.1 4.6e-09 37.2 7.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI42770.1 - 3.9e-07 29.6 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI42770.1 - 0.00027 20.7 1.3 0.00042 20.0 1.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KPI42770.1 - 0.038 13.6 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KPI42771.1 - 2.9e-18 66.5 0.1 5.8e-17 62.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI42771.1 - 7.1e-15 54.9 0.0 1.2e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI42771.1 - 2.6e-11 44.6 0.1 3.4e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KPI42771.1 - 3.4e-05 23.5 0.0 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPI42771.1 - 0.00013 21.5 0.1 0.0076 15.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KPI42771.1 - 0.00018 21.4 0.0 0.0096 15.7 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 KPI42771.1 - 0.0003 20.9 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 KPI42771.1 - 0.0044 16.7 0.0 0.0095 15.6 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.20 KPI42771.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 KPI42771.1 - 0.035 13.7 0.0 0.084 12.4 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S10 PF00450.22 KPI42771.1 - 0.22 10.9 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DUF1768 PF08719.11 KPI42773.1 - 1.4e-29 103.4 0.0 2.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ATP-grasp_2 PF08442.10 KPI42774.1 - 5.9e-79 264.3 0.6 1.1e-78 263.4 0.6 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KPI42774.1 - 1.7e-24 86.4 0.8 4.2e-24 85.1 0.8 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KPI42774.1 - 3e-09 36.7 0.1 7e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KPI42774.1 - 0.0041 16.9 1.2 0.01 15.6 0.1 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PAP1 PF08601.10 KPI42775.1 - 0.035 13.8 0.0 0.035 13.8 0.0 2.2 2 1 0 2 2 2 0 Transcription factor PAP1 Acyl_transf_3 PF01757.22 KPI42776.1 - 9.4e-20 70.9 26.7 1.2e-18 67.3 26.7 2.2 1 1 0 1 1 1 1 Acyltransferase family Proteasom_Rpn13 PF04683.13 KPI42777.1 - 1.9e-26 92.4 0.0 3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KPI42777.1 - 8.6e-10 38.8 2.2 2.1e-09 37.5 2.2 1.6 1 1 0 1 1 1 1 UCH-binding domain CD99L2 PF12301.8 KPI42777.1 - 0.2 12.0 1.4 0.18 12.1 0.2 1.6 2 0 0 2 2 2 0 CD99 antigen like protein 2 FMO-like PF00743.19 KPI42778.1 - 2.8e-15 55.8 0.6 9.1e-13 47.5 1.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI42778.1 - 2.6e-10 40.4 0.0 1.7e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI42778.1 - 6.3e-06 25.6 0.1 0.00038 19.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI42778.1 - 0.00017 20.9 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI42778.1 - 0.00026 21.0 0.0 0.35 10.9 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KPI42778.1 - 0.0015 18.2 0.3 3.4 7.1 0.0 3.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI42778.1 - 0.028 13.7 0.3 0.1 11.8 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI42778.1 - 0.17 11.1 0.0 9.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KPI42778.1 - 0.27 11.2 3.6 1.4 8.9 0.6 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sugar_tr PF00083.24 KPI42779.1 - 1.2e-40 139.8 18.1 1.6e-40 139.4 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42779.1 - 6.8e-09 35.1 14.3 6.8e-09 35.1 14.3 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily APG9 PF04109.16 KPI42780.1 - 4.2e-195 649.3 17.2 4.9e-195 649.1 17.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 UL42 PF17638.2 KPI42780.1 - 0.1 12.6 1.0 0.26 11.3 1.0 1.6 1 0 0 1 1 1 0 HCMV UL42 MtN3_slv PF03083.16 KPI42780.1 - 0.15 12.2 2.1 0.42 10.7 2.1 1.8 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PhyH PF05721.13 KPI42781.1 - 5.5e-12 46.4 0.0 1.3e-11 45.1 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Nop PF01798.18 KPI42783.1 - 7.5e-85 284.1 0.3 1.5e-84 283.1 0.3 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KPI42783.1 - 2.5e-21 75.8 3.2 1.3e-20 73.5 3.2 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain SUIM_assoc PF16619.5 KPI42785.1 - 0.0034 17.4 0.0 0.0062 16.6 0.0 1.5 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 HS1_rep PF02218.15 KPI42785.1 - 0.86 10.0 3.6 1.6 9.1 3.6 1.5 1 0 0 1 1 1 0 Repeat in HS1/Cortactin MCU PF04678.13 KPI42787.1 - 5.6e-28 98.2 0.0 1.1e-27 97.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter RasGAP PF00616.19 KPI42788.1 - 5.1e-35 121.1 0.0 6.9e-21 74.9 0.0 3.1 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KPI42788.1 - 0.0042 17.4 0.3 0.047 14.0 0.0 2.7 2 1 0 2 2 2 1 C2 domain DUF4351 PF14261.6 KPI42788.1 - 0.24 11.5 1.3 0.9 9.7 1.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Sugar_tr PF00083.24 KPI42790.1 - 9.8e-57 192.8 22.5 8.1e-56 189.8 22.0 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI42790.1 - 1.8e-10 40.3 31.4 3.8e-10 39.2 31.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 KPI42792.1 - 2.5e-26 92.8 0.0 4.2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 KPI42793.1 - 1.6e-11 43.7 0.2 2.9e-11 42.8 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI42794.1 - 2e-33 115.8 37.4 3.1e-33 115.2 37.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI42794.1 - 2.5e-09 36.5 25.7 5.1e-09 35.5 25.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter FeoB_C PF07664.12 KPI42794.1 - 0.00028 20.5 0.1 0.17 11.6 0.1 3.2 2 0 0 2 2 2 2 Ferrous iron transport protein B C terminus PCI PF01399.27 KPI42796.1 - 5.1e-07 30.2 0.3 4e-06 27.3 0.3 2.4 1 1 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KPI42796.1 - 5.1e-05 22.8 0.3 0.0001 21.8 0.3 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dimerisation2 PF16864.5 KPI42796.1 - 0.023 14.7 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Dimerisation domain Ribosomal_S17 PF00366.20 KPI42796.1 - 0.027 14.6 0.1 0.062 13.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S17 YfdX PF10938.8 KPI42796.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 YfdX protein DUF1912 PF08930.10 KPI42796.1 - 0.45 10.7 2.3 3.4 7.9 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF1912) Fungal_trans PF04082.18 KPI42797.1 - 7.3e-08 31.8 0.1 6.4e-07 28.7 0.2 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI42797.1 - 0.041 14.0 0.6 0.085 13.0 0.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxysterol_BP PF01237.18 KPI42798.1 - 2.7e-59 200.9 3.6 1.3e-50 172.3 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein NFACT-R_1 PF05670.13 KPI42799.1 - 1.1e-38 132.2 0.0 1.7e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain Pkinase_Tyr PF07714.17 KPI42800.1 - 4.3e-08 32.7 0.0 5.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KPI42800.1 - 5.2e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.27 KPI42802.1 - 6.2e-48 162.8 0.2 3.6e-24 85.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KPI42802.1 - 4.7e-25 87.5 0.7 1.2e-24 86.1 0.7 1.8 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 KPI42802.1 - 1.7e-16 60.9 2.0 0.0014 18.6 0.0 4.9 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI42802.1 - 1.3e-14 54.2 0.0 5.7e-06 25.9 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI42802.1 - 4.9e-08 32.6 0.1 0.014 15.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KPI42802.1 - 3.1e-07 31.1 11.7 0.00094 19.7 0.1 3.9 5 0 0 5 5 3 2 AAA domain AAA_28 PF13521.6 KPI42802.1 - 4.8e-07 30.2 0.1 0.017 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPI42802.1 - 1e-06 28.8 0.0 0.0015 18.5 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KPI42802.1 - 3.9e-06 27.2 0.0 0.065 13.5 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA PF00004.29 KPI42802.1 - 4.8e-06 27.0 0.1 0.088 13.2 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KPI42802.1 - 5.2e-06 26.3 0.0 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KPI42802.1 - 6.3e-06 26.3 0.0 0.0055 16.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KPI42802.1 - 1.6e-05 25.4 0.1 0.17 12.2 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 KPI42802.1 - 2.3e-05 24.9 0.1 0.38 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KPI42802.1 - 3.7e-05 23.9 0.0 0.59 10.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KPI42802.1 - 4.2e-05 23.5 0.0 0.038 13.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KPI42802.1 - 0.00031 20.6 0.7 1.5 8.5 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 KPI42802.1 - 0.00035 20.9 0.1 0.68 10.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_27 PF13514.6 KPI42802.1 - 0.00043 19.9 0.0 0.32 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KPI42802.1 - 0.00045 19.3 0.4 0.4 9.6 0.0 3.1 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KPI42802.1 - 0.00047 19.9 0.0 1.4 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KPI42802.1 - 0.00075 19.6 0.0 0.0052 16.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KPI42802.1 - 0.00075 19.3 0.0 0.97 9.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 KPI42802.1 - 0.00094 18.4 0.1 1.2 8.3 0.0 2.9 3 1 0 3 3 3 2 G-protein alpha subunit AAA_14 PF13173.6 KPI42802.1 - 0.001 19.1 0.1 2 8.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KPI42802.1 - 0.0011 19.1 2.2 0.23 11.5 0.1 3.4 3 1 0 3 3 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KPI42802.1 - 0.0013 18.9 0.0 0.88 9.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KPI42802.1 - 0.0018 17.9 0.0 1.8 8.1 0.0 3.3 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KPI42802.1 - 0.002 17.4 0.4 0.18 11.0 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain HEAT PF02985.22 KPI42802.1 - 0.003 17.7 0.0 14 6.3 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Roc PF08477.13 KPI42802.1 - 0.0033 17.6 0.0 3.1 8.1 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 KPI42802.1 - 0.0041 16.5 0.1 3.5 7.0 0.0 3.0 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KPI42802.1 - 0.0043 16.9 0.0 3.7 7.3 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KPI42802.1 - 0.0078 16.1 0.3 1.5 8.7 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KPI42802.1 - 0.0092 15.7 0.0 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KPI42802.1 - 0.012 15.5 0.0 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain CLP1_P PF16575.5 KPI42802.1 - 0.017 14.9 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KPI42802.1 - 0.019 15.0 0.1 6.2 6.8 0.0 3.1 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KPI42802.1 - 0.02 14.9 0.0 16 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KPI42802.1 - 0.027 14.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KPI42802.1 - 0.046 13.3 0.0 2.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPI42802.1 - 0.049 13.1 0.0 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KPI42802.1 - 0.064 12.3 0.0 9.4 5.2 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein dNK PF01712.19 KPI42802.1 - 0.065 13.1 0.0 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Deoxynucleoside kinase NTPase_1 PF03266.15 KPI42802.1 - 0.075 12.9 0.5 17 5.3 0.1 2.9 2 1 0 2 2 2 0 NTPase PRK PF00485.18 KPI42802.1 - 0.082 12.6 0.0 6.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 KPI42802.1 - 0.082 12.4 0.0 16 4.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Adaptin_N PF01602.20 KPI42802.1 - 0.089 11.3 0.2 13 4.2 0.0 2.9 2 1 1 3 3 3 0 Adaptin N terminal region MukB PF04310.12 KPI42802.1 - 0.11 12.3 0.1 26 4.5 0.0 2.7 3 0 0 3 3 2 0 MukB N-terminal Septin PF00735.18 KPI42802.1 - 0.12 11.6 0.6 3.8 6.7 0.0 2.6 3 0 0 3 3 2 0 Septin RuvB_N PF05496.12 KPI42802.1 - 0.14 11.9 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_13 PF13166.6 KPI42802.1 - 0.51 8.9 0.0 0.51 8.9 0.0 3.8 4 1 0 4 4 4 0 AAA domain HMA PF00403.26 KPI42803.1 - 2.7e-44 149.4 0.5 3.3e-12 46.7 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KPI42803.1 - 2.3e-36 126.1 1.5 5.9e-35 121.5 0.2 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KPI42803.1 - 1.6e-33 115.8 11.3 1.9e-17 63.3 0.4 3.3 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KPI42803.1 - 0.0062 16.3 0.4 0.016 15.0 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 KPI42803.1 - 0.0074 16.3 0.0 2.5 8.2 0.0 3.5 3 0 0 3 3 3 1 B12 binding domain TTc_toxin_rep PF18807.1 KPI42803.1 - 0.035 13.9 0.6 5.9 6.8 0.2 2.8 2 0 0 2 2 2 0 Tripartite Tc toxins repeat Sugar_tr PF00083.24 KPI42804.1 - 7.9e-10 38.2 0.3 9.3e-10 37.9 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42805.1 - 1.3e-41 142.7 46.6 1.1e-39 136.4 46.9 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI42805.1 - 1.1e-15 57.1 8.7 1.1e-15 57.1 8.7 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Beta-lactamase PF00144.24 KPI42806.1 - 1.1e-53 182.6 0.0 1.4e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Dynein_light PF01221.18 KPI42808.1 - 1.6e-40 137.3 1.3 1.9e-40 137.0 1.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M24 PF00557.24 KPI42808.1 - 0.067 12.9 0.1 0.076 12.7 0.1 1.0 1 0 0 1 1 1 0 Metallopeptidase family M24 Ground-like PF04155.18 KPI42808.1 - 0.086 13.5 0.2 0.12 13.0 0.2 1.3 1 0 0 1 1 1 0 Ground-like domain Transglut_i_TM PF14400.6 KPI42808.1 - 0.1 12.7 0.3 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices DUF5633 PF18656.1 KPI42808.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5633) RhoGEF67_u1 PF16615.5 KPI42808.1 - 0.2 12.2 0.1 0.29 11.7 0.1 1.2 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 Rtf2 PF04641.12 KPI42809.1 - 7.5e-57 192.7 1.7 8.9e-57 192.4 1.7 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KPI42809.1 - 1.2e-06 28.2 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KPI42809.1 - 0.032 14.0 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KPI42809.1 - 0.054 13.5 0.0 0.37 10.8 0.0 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-NOSIP PF15906.5 KPI42809.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KPI42809.1 - 0.07 13.5 0.0 0.28 11.5 0.0 2.0 1 1 1 2 2 2 0 Ring finger domain DUF4588 PF15251.6 KPI42811.1 - 3.6e-06 26.9 4.2 1e-05 25.5 4.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Zn_clus PF00172.18 KPI42812.1 - 2e-06 27.8 11.2 2e-06 27.8 11.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI42812.1 - 0.0004 19.3 0.3 0.0027 16.6 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Macoilin PF09726.9 KPI42812.1 - 0.051 12.1 3.3 0.067 11.8 3.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF3425 PF11905.8 KPI42814.1 - 2.8e-13 49.9 0.2 4.8e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Bromo_TP_like PF17027.5 KPI42815.1 - 0.003 17.7 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Histone-fold protein LysM PF01476.20 KPI42816.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain Nucleos_tra2_C PF07662.13 KPI42817.1 - 8.9e-73 244.5 1.1 8.9e-73 244.5 1.1 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KPI42817.1 - 2.3e-22 79.4 1.7 2.3e-22 79.4 1.7 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KPI42817.1 - 0.031 14.5 12.7 0.039 14.2 7.8 3.3 2 1 0 2 2 2 0 Nucleoside recognition ATP1G1_PLM_MAT8 PF02038.16 KPI42817.1 - 0.48 9.9 3.6 1.7 8.2 3.6 1.9 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF3087 PF11286.8 KPI42817.1 - 7.2 6.1 5.5 1.2 8.6 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) Aldo_ket_red PF00248.21 KPI42818.1 - 2.2e-47 161.7 0.0 1e-46 159.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family VirB7 PF17413.2 KPI42818.1 - 0.061 12.6 0.5 0.24 10.7 0.1 2.2 1 1 1 2 2 2 0 Outer membrane lipoprotein virB7 F-box-like PF12937.7 KPI42819.1 - 4.6e-06 26.4 0.0 9.6e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI42819.1 - 0.084 12.8 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 F-box domain Borrelia_P83 PF05262.11 KPI42820.1 - 0.67 8.4 3.7 0.81 8.1 3.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SRP-alpha_N PF04086.13 KPI42820.1 - 3.5 7.5 13.0 4.3 7.2 13.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 KPI42820.1 - 6.7 5.4 8.9 8.6 5.1 8.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KPI42820.1 - 8.2 5.1 7.5 11 4.7 7.5 1.2 1 0 0 1 1 1 0 Presenilin Thi4 PF01946.17 KPI42821.1 - 2.9e-86 288.5 0.3 1.5e-85 286.2 0.3 1.8 1 1 0 1 1 1 1 Thi4 family DAO PF01266.24 KPI42821.1 - 1.3e-05 25.0 0.8 5.1e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI42821.1 - 1.6e-05 24.2 3.2 0.0003 20.0 1.9 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI42821.1 - 4.1e-05 23.7 0.1 0.00013 22.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI42821.1 - 7.7e-05 21.9 1.1 0.00015 20.9 0.7 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI42821.1 - 0.00014 21.2 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI42821.1 - 0.0022 17.3 0.2 0.0032 16.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KPI42821.1 - 0.0037 16.4 0.6 0.0074 15.4 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KPI42821.1 - 0.0037 16.2 0.2 0.0052 15.7 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 KPI42821.1 - 0.0047 15.7 0.3 0.007 15.1 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KPI42821.1 - 0.037 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KPI42821.1 - 0.046 12.3 0.1 0.067 11.7 0.1 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KPI42821.1 - 0.13 12.3 0.6 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KPI42821.1 - 0.16 11.3 1.8 0.14 11.5 0.6 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Actin PF00022.19 KPI42822.1 - 1.8e-20 72.9 0.0 9.4e-16 57.4 0.0 3.1 2 1 0 2 2 2 2 Actin CUE PF02845.16 KPI42823.1 - 2.4e-06 27.1 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 KPI42823.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) UBA PF00627.31 KPI42823.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain SDA1 PF05285.12 KPI42824.1 - 5.4e-71 239.8 51.5 5.3e-52 177.4 17.3 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KPI42824.1 - 3.3e-21 75.3 0.2 1e-20 73.8 0.2 1.9 1 0 0 1 1 1 1 NUC130/3NT domain zinc_ribbon_15 PF17032.5 KPI42825.1 - 0.037 14.8 1.0 0.11 13.3 0.1 2.0 1 1 1 2 2 2 0 zinc-ribbon family AAA_2 PF07724.14 KPI42826.1 - 2.9e-47 160.9 0.0 5.5e-46 156.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KPI42826.1 - 9.6e-33 112.2 0.8 9.6e-33 112.2 0.8 4.7 5 2 3 8 8 5 1 AAA lid domain AAA PF00004.29 KPI42826.1 - 1.6e-26 93.3 0.0 3.1e-14 53.5 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KPI42826.1 - 4.9e-23 81.0 1.3 4.9e-23 81.0 1.3 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KPI42826.1 - 8.6e-15 54.9 0.0 2.3e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI42826.1 - 9.7e-14 51.8 2.3 8.3e-05 22.9 0.0 5.4 4 2 1 5 5 4 2 AAA domain AAA_16 PF13191.6 KPI42826.1 - 1.3e-13 51.7 3.0 4.7e-06 27.1 0.0 5.2 4 1 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KPI42826.1 - 8.4e-09 35.3 0.0 3.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 KPI42826.1 - 2.6e-06 27.5 0.1 0.035 14.0 0.3 4.1 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KPI42826.1 - 3.6e-06 26.8 0.0 0.094 12.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KPI42826.1 - 3.7e-06 27.5 1.4 0.087 13.4 0.0 4.1 4 0 0 4 4 2 2 AAA domain AAA_7 PF12775.7 KPI42826.1 - 4.6e-06 26.3 0.0 0.017 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KPI42826.1 - 8e-06 25.9 0.0 0.25 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KPI42826.1 - 1.6e-05 24.4 0.1 0.18 11.2 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KPI42826.1 - 2.2e-05 24.6 0.0 0.28 11.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KPI42826.1 - 6.8e-05 23.2 3.6 0.43 10.8 0.0 4.1 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KPI42826.1 - 8.8e-05 22.8 0.0 0.58 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KPI42826.1 - 0.0001 22.1 0.0 0.48 10.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain Clp_N PF02861.20 KPI42826.1 - 0.00011 22.2 1.7 0.48 10.6 0.0 3.4 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component ABC_tran PF00005.27 KPI42826.1 - 0.00012 22.6 0.4 0.44 11.1 0.0 3.5 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 KPI42826.1 - 0.00017 21.5 0.3 0.28 11.1 0.0 3.3 3 1 1 4 4 3 1 RsgA GTPase AAA_3 PF07726.11 KPI42826.1 - 0.00052 19.9 0.0 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KPI42826.1 - 0.00052 20.0 0.0 0.67 10.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KPI42826.1 - 0.00052 19.8 1.6 3.3 7.4 0.8 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KPI42826.1 - 0.00058 20.2 0.8 0.19 12.1 0.1 3.7 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KPI42826.1 - 0.0006 19.6 0.0 0.5 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 KPI42826.1 - 0.00071 19.7 0.0 0.0081 16.3 0.0 2.2 2 0 0 2 2 2 1 Torsin T2SSE PF00437.20 KPI42826.1 - 0.0013 17.8 0.3 0.051 12.6 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KPI42826.1 - 0.0016 18.2 0.0 1.4 8.7 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.15 KPI42826.1 - 0.0038 17.3 0.1 1.3 9.0 0.0 3.6 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 KPI42826.1 - 0.006 16.2 0.0 2.1 8.0 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KPI42826.1 - 0.0073 15.6 0.0 2.3 7.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 KPI42826.1 - 0.008 16.1 0.0 0.92 9.4 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Roc PF08477.13 KPI42826.1 - 0.0081 16.4 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KPI42826.1 - 0.013 15.4 0.0 0.53 10.2 0.0 3.2 3 0 0 3 3 3 0 NTPase Rad17 PF03215.15 KPI42826.1 - 0.039 13.9 0.0 8.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 KPI42826.1 - 0.044 13.5 0.1 8.1 6.2 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KPI42826.1 - 0.053 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KPI42826.1 - 0.1 12.2 1.2 16 5.0 0.0 3.4 3 1 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KPI42826.1 - 0.1 12.7 0.1 3 8.0 0.0 3.5 4 0 0 4 4 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KPI42826.1 - 0.13 12.1 0.1 21 4.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MEDS PF14417.6 KPI42826.1 - 0.24 11.2 2.2 1.8 8.4 0.3 3.4 4 0 0 4 4 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_23 PF13476.6 KPI42826.1 - 0.39 11.2 0.0 0.39 11.2 0.0 5.0 6 1 0 6 6 3 0 AAA domain Cep57_CLD_2 PF14197.6 KPI42826.1 - 2 8.6 17.2 0.11 12.6 6.3 3.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 KPI42826.1 - 4.3 5.1 6.1 0.52 8.2 1.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Beta_elim_lyase PF01212.21 KPI42827.1 - 1.6e-40 139.2 0.0 2e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KPI42827.1 - 5e-06 25.9 0.0 8.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3974 PF13120.6 KPI42827.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) ELO PF01151.18 KPI42829.1 - 2.2e-81 273.1 8.6 2.8e-81 272.7 8.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Apolipoprotein PF01442.18 KPI42829.1 - 2.9e-06 27.3 17.4 7.2e-06 26.0 17.4 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KPI42829.1 - 8.5 4.2 7.6 16 3.3 6.9 1.5 1 1 0 1 1 1 0 Prominin Arrestin_N PF00339.29 KPI42830.1 - 1.1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 KPI42830.1 - 0.00046 19.1 0.1 0.00093 18.1 0.1 1.4 1 0 0 1 1 1 1 Bul1 N terminus Cu-oxidase_2 PF07731.14 KPI42830.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Multicopper oxidase Bul1_C PF04426.12 KPI42830.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus Aminotran_3 PF00202.21 KPI42831.1 - 8.3e-68 228.9 0.1 1.3e-67 228.3 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III AAT PF03417.16 KPI42831.1 - 3.3e-24 85.8 0.0 5e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PaRep2b PF07775.11 KPI42831.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 PaRep2b protein Glucodextran_B PF09136.10 KPI42832.1 - 0.16 12.4 0.1 0.39 11.1 0.1 1.6 1 0 0 1 1 1 0 Glucodextranase, domain B HET PF06985.11 KPI42833.1 - 1.6e-32 112.9 0.3 2.5e-32 112.2 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Suv3_N PF18114.1 KPI42833.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Suv3 helical N-terminal domain OTCace PF00185.24 KPI42834.1 - 8.1e-44 149.5 0.0 1.4e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KPI42834.1 - 3.7e-38 130.9 0.0 7.2e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Fungal_trans PF04082.18 KPI42835.1 - 1.7e-05 24.0 0.1 2.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KPI42836.1 - 5.8e-53 179.9 0.0 7.1e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI42836.1 - 1.5e-40 138.7 0.0 1.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI42836.1 - 6.1e-09 36.0 0.0 2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI42836.1 - 0.002 17.6 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KPI42838.1 - 2.8e-21 75.9 0.6 3.6e-21 75.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42838.1 - 2.3e-15 56.8 0.8 2.9e-15 56.5 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI42838.1 - 2.7e-06 27.4 0.5 4.3e-06 26.8 0.4 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI42838.1 - 0.11 12.3 0.4 0.24 11.3 0.4 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Sda PF08970.10 KPI42839.1 - 1.6 8.5 5.4 21 4.9 0.0 3.7 4 0 0 4 4 4 0 Sporulation inhibitor A Pkinase PF00069.25 KPI42841.1 - 6.8e-63 212.5 0.0 9e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI42841.1 - 2.7e-28 99.0 0.0 3.6e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KPI42841.1 - 0.00016 22.3 1.3 0.0034 18.0 0.2 3.1 3 0 0 3 3 3 1 Protein kinase C terminal domain Tcf25 PF04910.14 KPI42842.1 - 1.3e-73 248.2 0.2 1.8e-73 247.6 0.2 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SR-25 PF10500.9 KPI42842.1 - 0.034 13.7 10.6 0.067 12.8 10.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_12 PF13424.6 KPI42842.1 - 0.073 13.4 2.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ORC6 PF05460.13 KPI42842.1 - 6.2 6.0 21.8 0.098 11.9 11.2 2.4 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF5516 PF17637.2 KPI42843.1 - 0.062 13.1 0.3 0.17 11.7 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5516) ORC6 PF05460.13 KPI42843.1 - 0.27 10.5 4.8 0.35 10.1 4.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Amidohydro_1 PF01979.20 KPI42844.1 - 1.1e-11 44.7 0.0 7.7e-07 28.7 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KPI42844.1 - 1.3e-11 44.7 0.9 2.2e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DFP PF04127.15 KPI42845.1 - 1.3e-16 61.0 0.0 7e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein UQ_con PF00179.26 KPI42846.1 - 1.1e-48 164.5 0.1 1.2e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPI42846.1 - 0.00012 21.8 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B LRR_4 PF12799.7 KPI42847.1 - 6.8e-09 35.9 11.9 0.0027 18.1 2.7 4.2 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI42847.1 - 7.2e-05 22.5 9.1 0.053 13.3 0.9 3.8 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KPI42847.1 - 0.00013 22.1 10.0 6.2 7.8 0.4 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KPI42847.1 - 0.0094 15.5 0.9 0.13 11.8 0.1 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KPI42847.1 - 0.022 14.8 11.5 0.2 11.8 0.9 4.7 5 0 0 5 5 5 0 Leucine Rich repeat XPC-binding PF09280.11 KPI42849.1 - 1.8e-22 78.8 8.4 4.2e-22 77.7 8.4 1.7 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KPI42849.1 - 1.1e-10 41.2 0.0 2.6e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain MCM_N PF14551.6 KPI42849.1 - 0.01 16.4 0.2 0.26 11.9 0.0 2.5 2 0 0 2 2 2 0 MCM N-terminal domain GDI PF00996.18 KPI42849.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF2408 PF10303.9 KPI42849.1 - 0.21 12.2 1.0 0.42 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Ribosomal_S8 PF00410.19 KPI42850.1 - 3.3e-21 75.5 0.2 5.2e-21 74.9 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Actin PF00022.19 KPI42851.1 - 1.6e-125 419.0 0.0 7.2e-125 416.8 0.0 1.8 1 1 0 1 1 1 1 Actin baeRF_family10 PF18854.1 KPI42851.1 - 0.16 12.2 0.1 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Asn_synthase PF00733.21 KPI42852.1 - 5.7e-91 305.8 0.6 1.3e-52 179.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KPI42852.1 - 6e-31 106.9 0.0 1.6e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KPI42852.1 - 3.2e-20 72.7 0.0 9.2e-20 71.2 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KPI42852.1 - 2.8e-06 27.0 0.0 1.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 KPI42852.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.5 1 1 0 1 1 1 0 NAD synthase Adap_comp_sub PF00928.21 KPI42854.1 - 4.2e-55 187.0 0.0 5.7e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KPI42854.1 - 0.004 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SLAC1 PF03595.17 KPI42855.1 - 9.3e-74 248.6 51.4 1.1e-73 248.4 51.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Cpn10 PF00166.21 KPI42855.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit FMO-like PF00743.19 KPI42856.1 - 8.7e-11 40.9 0.6 5.6e-09 35.0 0.2 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI42856.1 - 4.2e-09 36.0 0.0 1.1e-07 31.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI42856.1 - 2.2e-08 33.7 0.0 9.2e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI42856.1 - 7e-08 32.6 0.0 2.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI42856.1 - 8.9e-05 22.5 0.1 0.013 15.5 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI42856.1 - 0.0018 17.6 0.0 0.04 13.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI42856.1 - 0.33 11.5 0.8 43 4.8 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KPI42857.1 - 2.6e-63 214.4 0.0 3.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 KPI42859.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PRK PF00485.18 KPI42860.1 - 7.9e-05 22.5 0.0 0.00029 20.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KPI42860.1 - 0.00031 20.4 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.14 KPI42860.1 - 0.0013 18.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 KPI42860.1 - 0.0033 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KPI42860.1 - 0.0034 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KPI42860.1 - 0.0099 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.14 KPI42860.1 - 0.027 13.7 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KPI42860.1 - 0.03 14.9 0.0 0.063 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI42860.1 - 0.038 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KPI42860.1 - 0.04 14.3 0.1 0.075 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KPI42860.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 KPI42860.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Torsin PF06309.11 KPI42860.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin LpxK PF02606.14 KPI42860.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase APS_kinase PF01583.20 KPI42860.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KPI42860.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Cyclase PF04199.13 KPI42861.1 - 8.7e-29 100.5 0.1 1.1e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase TPT PF03151.16 KPI42862.1 - 2.4e-22 79.6 23.5 3e-22 79.3 23.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KPI42862.1 - 0.00025 20.4 25.1 0.0039 16.4 25.1 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KPI42862.1 - 0.00035 20.7 39.6 0.0004 20.6 15.2 2.5 3 0 0 3 3 3 2 EamA-like transporter family Dexa_ind PF15198.6 KPI42862.1 - 0.26 11.4 3.3 0.97 9.6 3.3 2.1 1 0 0 1 1 1 0 Dexamethasone-induced DUF4064 PF13273.6 KPI42864.1 - 0.065 13.5 0.1 1 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) MWFE PF15879.5 KPI42865.1 - 1e-17 64.1 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit adh_short PF00106.25 KPI42867.1 - 5.3e-85 283.8 8.6 1.3e-45 155.3 0.8 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42867.1 - 4.1e-64 216.3 3.2 1.1e-32 113.4 0.3 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KPI42867.1 - 1.2e-31 108.9 0.0 2.9e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KPI42867.1 - 8.7e-29 100.7 3.5 1.7e-13 50.9 0.2 2.5 2 0 0 2 2 2 2 KR domain Glucodextran_B PF09136.10 KPI42867.1 - 0.017 15.5 0.1 0.065 13.6 0.1 1.9 1 0 0 1 1 1 0 Glucodextranase, domain B THF_DHG_CYH_C PF02882.19 KPI42867.1 - 0.029 13.7 0.2 0.069 12.5 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4440 PF14534.6 KPI42869.1 - 0.0023 18.3 0.4 0.0064 16.9 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 KPI42869.1 - 0.0051 16.9 1.3 0.89 9.7 0.1 2.1 1 1 1 2 2 2 2 SnoaL-like domain SnoaL_3 PF13474.6 KPI42869.1 - 0.0073 16.6 0.3 0.58 10.4 0.3 2.2 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KPI42869.1 - 0.0093 16.6 0.3 1.1 10.0 0.1 1.9 1 1 1 2 2 2 2 SnoaL-like domain MttA_Hcf106 PF02416.16 KPI42870.1 - 0.16 11.3 2.9 0.28 10.6 2.9 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family Methyltransf_16 PF10294.9 KPI42871.1 - 2.2e-16 60.1 0.0 2.9e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KPI42871.1 - 7.5e-08 32.4 0.0 9.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI42871.1 - 0.068 13.9 0.0 0.51 11.1 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain PrmA PF06325.13 KPI42871.1 - 0.14 11.5 0.0 1.5 8.1 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Pro_CA PF00484.19 KPI42872.1 - 5.8e-15 55.9 0.1 3.5e-14 53.4 0.1 1.9 1 1 0 1 1 1 1 Carbonic anhydrase COesterase PF00135.28 KPI42873.1 - 5.8e-13 48.5 1.9 1.8e-12 46.9 1.9 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI42873.1 - 1.5e-10 41.3 0.2 1.9e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42873.1 - 0.0013 19.4 0.3 0.0017 19.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KPI42873.1 - 0.0032 16.4 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KPI42873.1 - 0.0093 14.9 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 KPI42873.1 - 0.018 13.5 0.6 0.29 9.6 0.0 2.3 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II Cyt-b5 PF00173.28 KPI42874.1 - 1.4e-12 47.5 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_3 PF07859.13 KPI42875.1 - 2e-41 142.2 0.0 2.5e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI42875.1 - 1.9e-05 24.2 0.2 0.0013 18.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KPI42875.1 - 2e-05 24.2 0.1 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.28 KPI42875.1 - 0.043 12.7 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Say1_Mug180 PF10340.9 KPI42875.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Zn_clus PF00172.18 KPI42876.1 - 0.0025 17.9 8.6 0.0052 16.9 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KPI42877.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain YihI PF04220.12 KPI42877.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) eIF3g PF12353.8 KPI42878.1 - 2.9e-39 134.3 4.8 4.4e-39 133.7 4.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KPI42878.1 - 2e-16 59.6 0.1 3.3e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KPI42878.1 - 0.014 15.7 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 ribosomal_L24 PF17136.4 KPI42878.1 - 0.021 15.2 1.1 0.021 15.2 1.1 2.2 2 0 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 RRM_occluded PF16842.5 KPI42878.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif ATHILA PF03078.15 KPI42878.1 - 0.07 11.9 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Hydrolase_4 PF12146.8 KPI42879.1 - 0.0006 19.1 0.0 0.00064 19.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI42879.1 - 0.0037 17.9 0.1 0.0041 17.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KPI42879.1 - 0.0048 16.8 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI42879.1 - 0.03 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF900 PF05990.12 KPI42879.1 - 0.17 11.4 0.1 0.43 10.0 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Zn_clus PF00172.18 KPI42880.1 - 2.4e-06 27.5 7.1 4.8e-06 26.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.20 KPI42881.1 - 1.1e-17 64.1 0.0 2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI42881.1 - 6.7e-13 48.9 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI42881.1 - 8.5e-13 48.3 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI42881.1 - 1.3e-09 38.2 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI42881.1 - 7.2e-08 32.5 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI42881.1 - 4.1e-06 26.7 0.2 9.7e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HSP9_HSP12 PF04119.12 KPI42882.1 - 5.3e-15 55.6 7.0 8.8e-15 54.8 7.0 1.4 1 0 0 1 1 1 1 Heat shock protein 9/12 Rtt106_N PF18215.1 KPI42883.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain PHD PF00628.29 KPI42885.1 - 3.6e-07 30.0 10.0 7.1e-07 29.0 10.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KPI42885.1 - 0.54 9.9 5.4 0.98 9.0 5.4 1.4 1 0 0 1 1 1 0 PHD-finger BTB PF00651.31 KPI42886.1 - 6.2e-08 32.8 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SAC3_GANP PF03399.16 KPI42887.1 - 1.4e-24 87.0 2.7 2.5e-22 79.6 2.7 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KPI42887.1 - 0.0016 18.4 0.1 0.0087 16.0 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF155 PF02582.14 KPI42888.1 - 2.1e-52 177.8 0.0 3.1e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SecG PF03840.14 KPI42888.1 - 0.073 13.2 0.1 0.72 10.0 0.3 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit zf-RING_2 PF13639.6 KPI42889.1 - 1.5e-11 44.4 9.2 2.4e-11 43.8 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KPI42889.1 - 7.5e-09 35.7 6.3 1.4e-08 34.9 6.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KPI42889.1 - 1.8e-06 27.7 7.9 2.9e-06 27.0 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI42889.1 - 1.2e-05 24.9 4.6 2.3e-05 24.0 4.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KPI42889.1 - 1.5e-05 24.5 5.7 2.7e-05 23.7 5.7 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KPI42889.1 - 1.9e-05 24.4 9.5 3e-05 23.8 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KPI42889.1 - 2.3e-05 24.4 2.0 0.00011 22.2 2.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KPI42889.1 - 0.00047 20.1 7.9 0.00072 19.5 7.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI42889.1 - 0.0022 18.0 6.5 0.0048 16.9 6.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPI42889.1 - 0.024 14.5 6.9 0.039 13.8 6.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI42889.1 - 0.026 14.4 5.3 0.044 13.7 5.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KPI42889.1 - 0.031 14.3 1.5 0.06 13.4 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 KPI42889.1 - 0.056 13.3 5.1 0.13 12.1 4.1 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 KPI42889.1 - 0.075 13.2 10.1 0.12 12.5 10.1 1.3 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KPI42889.1 - 0.099 12.8 5.9 0.2 11.9 5.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_5 PF17121.5 KPI42889.1 - 1.8 8.5 4.6 3.3 7.7 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KPI42889.1 - 4 7.8 7.5 7.4 7.0 7.5 1.4 1 0 0 1 1 1 0 RING-like domain Cupin_2 PF07883.11 KPI42890.1 - 9.8e-10 38.0 0.4 9.8e-10 38.0 0.4 2.3 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KPI42890.1 - 1.4e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KPI42890.1 - 0.00028 20.8 0.0 0.00028 20.8 0.0 2.5 2 1 1 3 3 3 1 AraC-like ligand binding domain JmjC PF02373.22 KPI42890.1 - 0.065 13.7 0.1 0.29 11.6 0.1 2.2 1 1 0 1 1 1 0 JmjC domain, hydroxylase FdtA PF05523.11 KPI42890.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal Aa_trans PF01490.18 KPI42891.1 - 4.6e-33 114.5 31.9 4.6e-33 114.5 31.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Epimerase PF01370.21 KPI42892.1 - 7.4e-17 61.6 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI42892.1 - 1.6e-15 57.5 0.0 2.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI42892.1 - 3.9e-15 56.0 0.0 5.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KPI42892.1 - 7e-15 54.8 0.1 1.2e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPI42892.1 - 9.2e-12 45.0 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KPI42892.1 - 6.7e-08 32.0 0.0 9.8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KPI42892.1 - 1.2e-07 31.2 0.0 2.6e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPI42892.1 - 5.9e-07 28.9 0.4 0.00027 20.2 0.5 2.8 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.25 KPI42892.1 - 1.2e-05 24.9 0.0 2.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI42892.1 - 0.003 17.2 0.0 0.0099 15.5 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI42892.1 - 0.0065 16.4 0.0 0.7 9.8 0.0 2.3 1 1 0 1 1 1 1 KR domain YfdX PF10938.8 KPI42893.1 - 0.0082 16.1 4.9 0.018 15.0 4.9 1.5 1 0 0 1 1 1 1 YfdX protein TPR_MLP1_2 PF07926.12 KPI42893.1 - 0.052 13.6 6.8 0.076 13.1 6.8 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 KPI42893.1 - 0.1 12.8 2.5 0.22 11.8 2.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KPI42893.1 - 0.15 11.2 3.2 0.2 10.7 3.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPL4 PF05021.15 KPI42894.1 - 3.4e-134 447.0 0.0 4.1e-134 446.8 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KPI42894.1 - 9e-71 236.7 0.7 1.3e-70 236.1 0.7 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region MIP PF00230.20 KPI42894.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Major intrinsic protein Clr2 PF10383.9 KPI42895.1 - 2.3e-16 60.9 0.0 8e-16 59.1 0.0 2.0 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KPI42895.1 - 7.9e-15 55.5 0.2 1.5e-14 54.5 0.2 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 DHFR_2 PF06442.11 KPI42895.1 - 0.019 14.8 0.4 0.086 12.7 0.1 2.1 2 0 0 2 2 2 0 R67 dihydrofolate reductase DUF2353 PF09789.9 KPI42896.1 - 0.0048 16.3 18.9 0.0095 15.3 18.9 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 KPI42896.1 - 1.6 7.6 21.0 5.9 5.7 20.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 KPI42896.1 - 1.9 9.0 15.1 0.63 10.5 0.2 3.6 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.16 KPI42896.1 - 4.7 6.0 4.5 7 5.4 4.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KPI42896.1 - 9.7 5.4 18.2 1.9 7.8 14.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KPI42897.1 - 2.3e-33 115.6 37.9 2.3e-33 115.6 37.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI42897.1 - 9.4e-06 25.2 27.4 0.00015 21.2 27.4 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Aldedh PF00171.22 KPI42898.1 - 4e-152 506.9 0.3 7.2e-152 506.1 0.1 1.4 2 0 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI42898.1 - 0.00016 21.2 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 KPI42898.1 - 0.18 10.8 0.4 0.36 9.8 0.4 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Dicty_REP PF05086.12 KPI42899.1 - 0.61 8.0 5.7 0.81 7.6 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.22 KPI42900.1 - 2.8e-54 183.1 0.0 3.3e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI42900.1 - 1.3e-21 77.0 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI42900.1 - 1.7e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPI42900.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KPI42900.1 - 0.0091 15.2 0.0 0.015 14.5 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KPI42900.1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPI42900.1 - 0.031 14.3 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI42900.1 - 0.051 13.5 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KPI42900.1 - 0.17 12.3 0.2 0.31 11.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain CN_hydrolase PF00795.22 KPI42901.1 - 8.4e-58 195.8 0.0 9.4e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP-synt_G PF04718.15 KPI42902.1 - 2.3e-15 57.2 0.1 1.2e-14 54.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit GARP PF16731.5 KPI42902.1 - 0.00045 20.0 1.1 0.0006 19.6 1.1 1.1 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma SOG2 PF10428.9 KPI42903.1 - 0.17 11.0 5.8 0.23 10.6 5.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BRD4_CDT PF17105.5 KPI42903.1 - 1.3 8.7 7.0 2 8.1 7.0 1.3 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 ACPS PF01648.20 KPI42904.1 - 2.1e-11 43.9 0.0 4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KPI42904.1 - 0.088 12.9 2.0 12 6.1 0.3 2.7 3 0 0 3 3 3 0 4'-phosphopantetheinyl transferase N-terminal domain SH3_1 PF00018.28 KPI42905.1 - 7e-25 86.4 0.0 3.3e-11 42.6 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KPI42905.1 - 2e-13 50.0 0.1 8.6e-06 25.5 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KPI42905.1 - 4.1e-12 45.6 0.0 1.1e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KPI42905.1 - 3e-10 40.1 0.0 6.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KPI42905.1 - 3.4e-08 33.3 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain RRM_1 PF00076.22 KPI42906.1 - 2.2e-72 238.8 0.1 2.5e-20 72.0 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI42906.1 - 2.5e-10 40.1 0.0 0.00031 20.5 0.0 4.7 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KPI42906.1 - 2.6e-06 27.0 0.0 0.48 10.0 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI42906.1 - 0.0017 18.4 0.0 12 6.2 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KPI42906.1 - 0.055 13.5 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NOP5NT PF08156.13 KPI42906.1 - 0.095 13.1 0.2 1.2 9.6 0.2 2.9 2 0 0 2 2 2 0 NOP5NT (NUC127) domain ATP19 PF11022.8 KPI42907.1 - 1e-22 80.2 0.0 1.2e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MFS_1 PF07690.16 KPI42908.1 - 6.2e-21 74.7 34.8 6.2e-21 74.7 34.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1304 PF06993.12 KPI42908.1 - 0.88 9.6 7.8 6.2 6.9 1.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) GMC_oxred_N PF00732.19 KPI42910.1 - 7.6e-59 199.5 0.0 9.9e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI42910.1 - 9.3e-30 104.0 0.1 1.9e-29 103.0 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI42910.1 - 1.9e-05 23.9 0.3 3.8e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KPI42910.1 - 9e-05 22.2 2.6 0.0025 17.5 2.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI42910.1 - 0.00027 20.2 0.8 0.0013 17.9 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI42910.1 - 0.0033 17.6 0.3 0.0099 16.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI42910.1 - 0.0068 15.7 0.2 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KPI42910.1 - 0.054 12.7 0.1 0.32 10.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 KPI42912.1 - 0.0021 18.3 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Umbravirus_LDM PF04817.12 KPI42914.1 - 0.051 12.9 0.6 7.7 5.8 0.1 2.4 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family LEP503 PF15221.6 KPI42914.1 - 0.93 9.9 3.1 15 6.0 0.0 3.5 3 1 1 4 4 4 0 Lens epithelial cell protein LEP503 GFA PF04828.14 KPI42915.1 - 5.6e-19 68.3 2.7 8.4e-19 67.7 2.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ADH_zinc_N PF00107.26 KPI42916.1 - 2.2e-12 47.1 0.0 2.7e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pam16 PF03656.13 KPI42917.1 - 4.6e-33 113.9 0.2 5.3e-33 113.7 0.2 1.0 1 0 0 1 1 1 1 Pam16 PHO4 PF01384.20 KPI42918.1 - 1.3e-77 261.1 9.1 1.7e-77 260.8 9.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.18 KPI42918.1 - 0.18 12.0 0.1 0.64 10.3 0.1 1.9 1 0 0 1 1 1 0 Glycophorin A Tim17 PF02466.19 KPI42918.1 - 1.9 8.9 7.0 0.27 11.6 1.0 2.7 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family CbiQ PF02361.16 KPI42918.1 - 3 7.4 14.8 2.4 7.7 0.3 2.7 2 1 1 3 3 3 0 Cobalt transport protein Adeno_E3_CR2 PF02439.15 KPI42918.1 - 5.2 6.9 5.8 0.72 9.7 0.6 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2417 PF10329.9 KPI42919.1 - 6.2e-84 281.1 0.1 9e-84 280.6 0.1 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 KPI42919.1 - 0.09 12.4 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold RCR PF12273.8 KPI42919.1 - 1.2 9.8 5.2 17 6.1 0.0 3.1 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF2070 PF09843.9 KPI42919.1 - 5.4 5.2 12.9 7.8 4.7 12.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CHD5 PF04420.14 KPI42920.1 - 1.2e-49 168.2 0.0 1.5e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 CHD5-like protein RGS PF00615.19 KPI42921.1 - 2.2e-13 50.5 0.0 8.5e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Aa_trans PF01490.18 KPI42922.1 - 8.7e-62 209.1 16.6 1.2e-61 208.7 16.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAN_1 PF00024.26 KPI42922.1 - 1.6e-09 37.6 15.0 0.00032 20.6 3.2 3.5 3 0 0 3 3 3 3 PAN domain Trp_Tyr_perm PF03222.13 KPI42922.1 - 0.2 10.7 17.6 0.44 9.5 17.6 1.4 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family SKG6 PF08693.10 KPI42922.1 - 0.2 11.1 0.6 0.63 9.5 0.6 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PAN_3 PF08277.12 KPI42922.1 - 1.6 8.6 7.0 14 5.6 0.2 3.4 3 0 0 3 3 3 0 PAN-like domain XPG_I PF00867.18 KPI42923.1 - 1.9e-23 82.6 0.0 3.8e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KPI42923.1 - 5.7e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain PIG-H PF10181.9 KPI42925.1 - 5.8e-24 83.7 1.0 1.1e-23 82.9 1.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ADH_N PF08240.12 KPI42926.1 - 3.6e-22 78.3 0.3 4.8e-22 77.9 0.3 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L22 PF00237.19 KPI42927.1 - 6.9e-43 145.1 0.1 9.7e-43 144.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ATP_bind_1 PF03029.17 KPI42928.1 - 8.2e-72 241.9 0.0 1.4e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KPI42928.1 - 6.9e-06 25.2 0.0 0.0048 15.9 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KPI42928.1 - 2.8e-05 23.7 0.0 0.0019 17.8 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KPI42928.1 - 0.00014 21.2 0.1 0.0063 15.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 KPI42928.1 - 0.0011 19.1 0.0 0.02 14.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KPI42928.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI42928.1 - 0.0026 18.2 0.0 0.008 16.6 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KPI42928.1 - 0.0036 17.5 0.6 0.008 16.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain SRP54 PF00448.22 KPI42928.1 - 0.0037 16.9 0.0 0.0099 15.5 0.0 1.7 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 KPI42928.1 - 0.0048 16.7 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop G-alpha PF00503.20 KPI42928.1 - 0.0071 15.5 0.0 0.31 10.1 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit FeoB_N PF02421.18 KPI42928.1 - 0.0072 15.9 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 KPI42928.1 - 0.0074 16.6 0.0 0.024 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KPI42928.1 - 0.0078 16.1 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KPI42928.1 - 0.0093 15.7 1.5 0.89 9.2 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase AAA_7 PF12775.7 KPI42928.1 - 0.01 15.4 0.0 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KPI42928.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KPI42928.1 - 0.018 14.5 0.0 3.6 7.0 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Roc PF08477.13 KPI42928.1 - 0.019 15.2 0.0 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KPI42928.1 - 0.02 14.6 0.2 0.12 12.1 0.0 2.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KPI42928.1 - 0.02 14.8 0.1 9.6 6.1 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase PRK PF00485.18 KPI42928.1 - 0.02 14.6 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KPI42928.1 - 0.034 13.4 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 KPI42928.1 - 0.043 13.4 0.1 0.45 10.1 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KPI42928.1 - 0.083 12.8 0.2 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KPI42928.1 - 0.14 11.6 0.1 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein APS_kinase PF01583.20 KPI42928.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KPI42928.1 - 0.49 10.9 2.5 2.3 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain CHZ PF09649.10 KPI42929.1 - 0.00012 21.5 1.5 0.00026 20.4 1.5 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ F-box-like_2 PF13013.6 KPI42930.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 F-box-like domain Hva1_TUDOR PF11160.8 KPI42931.1 - 2.2e-15 56.5 3.4 2.2e-15 56.5 3.4 2.9 2 1 1 3 3 3 1 Hypervirulence associated proteins TUDOR domain CDC45 PF02724.14 KPI42931.1 - 1.3 7.2 20.2 1.4 7.1 20.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KPI42931.1 - 6.6 5.4 16.3 8.4 5.1 16.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Fasciclin PF02469.22 KPI42932.1 - 2.3e-18 66.6 0.2 1.2e-08 35.2 0.0 2.3 2 1 0 2 2 2 2 Fasciclin domain XPC-binding PF09280.11 KPI42932.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 XPC-binding domain FAD_binding_3 PF01494.19 KPI42934.1 - 4.5e-19 68.9 0.0 6.7e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI42934.1 - 0.00023 20.9 1.0 0.19 11.2 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI42934.1 - 0.00024 21.1 2.9 0.012 15.6 0.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KPI42934.1 - 0.00077 19.6 0.1 0.0021 18.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KPI42934.1 - 0.0019 17.0 0.2 0.037 12.7 0.2 2.3 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KPI42934.1 - 0.006 15.5 0.1 0.032 13.1 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KPI42934.1 - 0.014 14.6 0.1 0.028 13.6 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPI42934.1 - 0.017 14.2 0.0 0.061 12.4 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 KPI42934.1 - 0.042 12.9 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KPI42934.1 - 0.051 12.9 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Mce4_CUP1 PF11887.8 KPI42934.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative OTT_1508_deam PF14441.6 KPI42935.1 - 3e-17 62.4 0.1 5.5e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase WSC PF01822.19 KPI42936.1 - 2.1e-13 50.3 11.9 4e-13 49.3 11.9 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 KPI42936.1 - 1.7e-06 27.3 6.8 1.7e-06 27.3 6.8 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 KPI42936.1 - 0.017 14.9 1.8 0.041 13.6 1.8 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4448 PF14610.6 KPI42936.1 - 0.039 13.7 0.0 0.088 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) MLANA PF14991.6 KPI42936.1 - 0.043 14.1 0.0 2.2 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein melan-A EphA2_TM PF14575.6 KPI42936.1 - 0.069 14.0 0.0 0.16 12.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 KPI42936.1 - 0.077 12.8 0.5 8.3 6.3 0.2 2.3 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Gram_pos_anchor PF00746.21 KPI42936.1 - 0.088 12.8 0.3 0.088 12.8 0.3 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF4366 PF14283.6 KPI42936.1 - 0.16 12.0 0.3 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Podoplanin PF05808.11 KPI42936.1 - 0.18 11.9 3.5 0.16 12.1 1.2 2.0 2 0 0 2 2 2 0 Podoplanin PGF-CTERM PF18204.1 KPI42936.1 - 0.36 10.9 4.9 1 9.4 4.9 1.8 1 0 0 1 1 1 0 PGF-CTERM motif UCH PF00443.29 KPI42937.1 - 2.4e-36 125.5 0.1 1.4e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI42937.1 - 1.2e-15 57.9 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.13 KPI42937.1 - 1.6 8.4 4.4 0.35 10.6 0.5 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Herpes_BLLF1 PF05109.13 KPI42937.1 - 2.2 6.2 10.4 3 5.7 10.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Methyltransf_23 PF13489.6 KPI42938.1 - 5.2e-20 71.9 0.0 8.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI42938.1 - 3.4e-11 43.7 0.0 8.5e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI42938.1 - 3.1e-09 36.8 0.0 7.8e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI42938.1 - 3.8e-09 37.1 0.0 8.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI42938.1 - 1.3e-07 32.3 0.0 8.4e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KPI42938.1 - 0.00035 20.1 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KPI42938.1 - 0.00066 19.2 0.0 0.003 17.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPI42938.1 - 0.0008 19.0 0.0 0.0076 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KPI42938.1 - 0.00089 18.6 0.0 0.0016 17.8 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KPI42938.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 KPI42938.1 - 0.057 12.8 0.0 0.4 10.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KPI42938.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S8 PF00082.22 KPI42939.1 - 2.7e-44 151.6 0.8 5.6e-44 150.6 0.8 1.5 1 0 0 1 1 1 1 Subtilase family Gpr1_Fun34_YaaH PF01184.19 KPI42940.1 - 1e-31 110.1 21.3 1.3e-31 109.9 21.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Tetraspanin PF00335.20 KPI42940.1 - 3 7.5 10.0 4.9 6.8 10.0 1.3 1 0 0 1 1 1 0 Tetraspanin family TBCC PF07986.12 KPI42941.1 - 2.1e-24 85.6 7.4 2.5e-24 85.3 5.1 2.3 1 1 1 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 KPI42941.1 - 1.1e-11 45.2 0.1 2.9e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Cytochrom_B562 PF07361.11 KPI42941.1 - 0.12 13.0 0.3 13 6.6 0.1 2.7 1 1 1 2 2 2 0 Cytochrome b562 IBR PF01485.21 KPI42942.1 - 1.8e-06 28.0 26.4 1.4e-05 25.2 3.9 4.8 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain CUE PF02845.16 KPI42942.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 CUE domain Yip1 PF04893.17 KPI42943.1 - 1.1e-09 38.3 14.2 2e-09 37.4 14.2 1.5 1 0 0 1 1 1 1 Yip1 domain zf-CCCH PF00642.24 KPI42944.1 - 4.4e-11 42.4 12.1 2.8e-06 27.1 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KPI42944.1 - 6.2e-10 38.6 10.2 2.7e-05 23.8 2.1 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KPI42944.1 - 6.4e-09 36.5 6.7 9.7e-05 23.0 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KPI42944.1 - 9.2e-09 35.1 19.6 4.2e-05 23.5 4.8 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KPI42944.1 - 0.00056 20.1 1.9 0.00099 19.3 1.9 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KPI42944.1 - 0.042 14.3 14.9 0.87 10.2 3.1 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Con-6 PF10346.9 KPI42945.1 - 5.1e-11 42.4 0.5 8.2e-11 41.8 0.5 1.4 1 0 0 1 1 1 1 Conidiation protein 6 GDI PF00996.18 KPI42946.1 - 2.9e-187 622.5 0.0 3.4e-187 622.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KPI42946.1 - 0.0081 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI42946.1 - 0.018 15.6 0.2 0.32 11.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rad1 PF02144.16 KPI42947.1 - 3.4e-67 226.4 0.0 4.1e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 BTB PF00651.31 KPI42948.1 - 1.2e-11 44.8 0.4 3.1e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KPI42948.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain RICTOR_M PF14666.6 KPI42948.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Ribosomal_S2 PF00318.20 KPI42949.1 - 8.6e-27 93.8 0.1 8.5e-15 54.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KPI42949.1 - 0.00023 22.4 6.4 0.00049 21.4 6.4 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus NTP_transf_9 PF04248.12 KPI42950.1 - 0.032 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Aldedh PF00171.22 KPI42951.1 - 3.1e-73 246.9 0.0 3.9e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpb2_1 PF04563.15 KPI42951.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase beta subunit MFS_1 PF07690.16 KPI42952.1 - 1.8e-27 96.2 62.4 9.5e-21 74.1 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_MLP1_2 PF07926.12 KPI42953.1 - 0.0014 18.6 4.1 0.0014 18.6 4.1 2.8 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein DUF3037 PF11236.8 KPI42953.1 - 0.61 10.5 2.9 0.93 9.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) End3 PF12761.7 KPI42953.1 - 1.4 9.0 9.9 2.6 8.2 9.9 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Erythro_esteras PF05139.14 KPI42953.1 - 1.8 8.3 5.7 3.8 7.2 3.2 2.0 2 0 0 2 2 2 0 Erythromycin esterase DUF5595 PF18077.1 KPI42953.1 - 2.1 8.5 6.4 21 5.3 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) KxDL PF10241.9 KPI42953.1 - 3 8.2 11.6 9.6 6.6 0.3 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein FUSC PF04632.12 KPI42953.1 - 5.8 5.3 7.4 18 3.7 3.5 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family COesterase PF00135.28 KPI42954.1 - 1.1e-77 262.0 0.2 1.4e-77 261.7 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI42954.1 - 2.3e-07 30.9 0.1 4.1e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI42954.1 - 0.005 16.3 0.2 0.0079 15.7 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family GvpH PF05455.11 KPI42956.1 - 0.086 12.9 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 GvpH PCI PF01399.27 KPI42957.1 - 0.019 15.5 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 PCI domain CSN7a_helixI PF18392.1 KPI42957.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain SnoaL_2 PF12680.7 KPI42958.1 - 0.0021 18.7 0.0 0.0027 18.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain LRR_10 PF18805.1 KPI42958.1 - 0.086 12.5 1.6 0.2 11.3 1.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeat Abhydrolase_6 PF12697.7 KPI42959.1 - 2.6e-09 38.0 0.0 3.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI42959.1 - 0.008 15.8 0.0 0.0096 15.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Phage_C PF12025.8 KPI42959.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage protein C Acyl_transf_3 PF01757.22 KPI42960.1 - 8.3e-05 21.8 13.9 0.019 14.0 8.3 2.2 2 0 0 2 2 2 2 Acyltransferase family Ribosomal_L6 PF00347.23 KPI42961.1 - 4.3e-25 88.2 11.4 3.5e-13 50.0 4.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 ESM4 PF15952.5 KPI42961.1 - 0.044 14.2 0.1 0.058 13.8 0.1 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family MTP18 PF10558.9 KPI42962.1 - 8.9e-81 269.9 0.2 1.1e-80 269.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_18 PF00704.28 KPI42964.1 - 1.7e-16 60.9 0.0 3e-16 60.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.7 KPI42965.1 - 2.1e-15 58.0 2.2 2.6e-15 57.6 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI42965.1 - 6.2e-05 22.8 0.1 9.7e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KPI42965.1 - 0.049 13.4 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KPI42965.1 - 0.054 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 KPI42965.1 - 0.054 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Chlorophyllase2 PF12740.7 KPI42965.1 - 0.2 10.6 0.2 0.71 8.7 0.2 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Glyco_hydro_17 PF00332.18 KPI42966.1 - 1.3e-09 38.1 0.2 2e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Putative_PNPOx PF01243.20 KPI42967.1 - 1.4e-09 38.0 0.0 3.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Asp PF00026.23 KPI42968.1 - 4.7e-71 239.8 4.5 4.7e-71 239.8 4.5 1.6 1 1 1 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI42968.1 - 2.4e-08 34.4 1.4 2.4e-08 34.4 1.4 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI42968.1 - 4.7e-05 23.9 2.7 0.14 12.9 0.0 3.0 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI42968.1 - 0.0013 19.2 0.0 1.7 9.2 0.0 3.0 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KPI42968.1 - 0.0014 18.5 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal SCIMP PF15050.6 KPI42969.1 - 0.059 13.8 0.6 0.059 13.8 0.6 1.9 2 0 0 2 2 2 0 SCIMP protein Ribosomal_S15 PF00312.22 KPI42970.1 - 1e-10 41.7 0.3 1.8e-10 40.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 HSF_DNA-bind PF00447.17 KPI42971.1 - 1.6e-30 105.6 1.3 2.4e-30 105.0 1.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Chisel PF15355.6 KPI42972.1 - 0.042 14.1 0.1 0.081 13.2 0.1 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel NTP_transf_9 PF04248.12 KPI42973.1 - 1e-19 70.2 0.3 1.3e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) AFG1_ATPase PF03969.16 KPI42976.1 - 2.8e-99 332.4 0.1 1.7e-94 316.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 KPI42976.1 - 0.00054 19.9 0.1 0.22 11.3 0.1 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 KPI42976.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI42976.1 - 0.0024 18.3 0.1 0.33 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KPI42976.1 - 0.036 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KPI42976.1 - 0.043 14.3 0.0 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI42976.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPI42976.1 - 0.08 13.3 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Abhydrolase_1 PF00561.20 KPI42977.1 - 2.8e-17 63.2 0.7 5.5e-17 62.3 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI42977.1 - 4.2e-16 60.2 1.0 6.3e-16 59.6 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI42977.1 - 3.5e-09 36.3 0.1 5.5e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPI42977.1 - 7.2e-05 23.0 0.1 0.025 14.7 0.1 2.2 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KPI42977.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KPI42977.1 - 0.001 17.8 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Lipase_3 PF01764.25 KPI42977.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KPI42977.1 - 0.0037 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KPI42977.1 - 0.0049 16.6 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 KPI42977.1 - 0.056 13.3 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 KPI42977.1 - 0.16 11.4 0.1 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Sugar_tr PF00083.24 KPI42979.1 - 2.9e-84 283.5 15.8 3.3e-84 283.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI42979.1 - 1e-14 54.2 44.8 6.6e-13 48.3 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_9 PF13371.6 KPI42979.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MCU PF04678.13 KPI42979.1 - 0.88 9.7 3.3 49 3.9 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial calcium uniporter GST_N_4 PF17172.4 KPI42980.1 - 1e-17 64.7 0.0 1.7e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KPI42980.1 - 1.2e-12 47.4 0.0 2.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KPI42980.1 - 4.9e-09 36.5 0.0 8.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KPI42980.1 - 3.8e-08 33.6 0.0 7.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI42980.1 - 0.00086 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI42980.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPI42981.1 - 5.3e-12 46.0 0.0 1.2e-11 44.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI42981.1 - 7.7e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI42981.1 - 2.9e-10 40.3 0.0 5.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI42981.1 - 2.2e-06 27.8 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI42981.1 - 4.4e-06 26.8 0.0 7.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI42981.1 - 0.032 14.2 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Csm1 PF12539.8 KPI42982.1 - 5.8e-29 100.6 0.2 1.2e-28 99.6 0.2 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TPR_MLP1_2 PF07926.12 KPI42982.1 - 0.0018 18.4 12.8 0.0018 18.4 12.8 2.5 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KPI42982.1 - 0.0026 15.8 3.1 0.0026 15.8 3.1 1.6 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family DUF573 PF04504.14 KPI42982.1 - 0.014 16.0 4.4 0.1 13.3 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function, DUF573 USP8_interact PF08941.10 KPI42982.1 - 0.025 14.4 0.3 0.025 14.4 0.3 1.9 2 0 0 2 2 2 0 USP8 interacting Spc7 PF08317.11 KPI42982.1 - 0.033 13.1 6.9 0.087 11.7 6.9 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4763 PF15960.5 KPI42982.1 - 0.041 13.2 5.6 0.074 12.4 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF948 PF06103.11 KPI42982.1 - 0.63 10.3 6.1 0.89 9.9 1.4 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC-167 PF15188.6 KPI42982.1 - 1.2 9.5 9.5 2.6 8.4 8.3 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 GIT_CC PF16559.5 KPI42982.1 - 2 8.4 9.7 0.33 10.8 5.2 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Rep_1 PF01446.17 KPI42982.1 - 2.4 7.6 6.0 3.1 7.2 1.4 2.3 1 1 1 2 2 2 0 Replication protein Bap31_Bap29_C PF18035.1 KPI42982.1 - 2.9 8.0 13.4 27 4.8 4.3 3.5 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain GAS PF13851.6 KPI42982.1 - 8.1 5.7 19.2 0.28 10.5 7.0 2.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding MCC-bdg_PDZ PF10506.9 KPI42982.1 - 9.8 6.3 11.4 2.5 8.2 1.4 2.5 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ribosomal_L6e PF01159.19 KPI42983.1 - 3.5e-41 140.2 0.6 3.5e-41 140.2 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 KPI42983.1 - 0.0038 16.7 0.2 0.0071 15.8 0.2 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 COG6 PF06419.11 KPI42984.1 - 3.9e-154 514.3 0.4 4.8e-154 514.0 0.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF717 PF05338.12 KPI42984.1 - 0.2 11.8 2.7 9.7 6.4 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF717) GED PF02212.18 KPI42984.1 - 0.22 11.7 2.3 34 4.7 0.5 3.4 3 0 0 3 3 3 0 Dynamin GTPase effector domain GARP PF16731.5 KPI42984.1 - 0.24 11.1 4.8 7.3 6.2 0.3 3.2 3 0 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF948 PF06103.11 KPI42984.1 - 0.24 11.7 2.7 2.2 8.6 0.1 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4698 PF15769.5 KPI42984.1 - 0.25 10.4 4.3 0.55 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) PI3_PI4_kinase PF00454.27 KPI42986.1 - 8.9e-48 163.3 0.0 2.2e-47 162.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KPI42986.1 - 3.1e-38 131.9 3.3 1e-37 130.2 3.3 2.0 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KPI42986.1 - 5.2e-25 87.3 0.0 2.5e-24 85.1 0.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KPI42986.1 - 6.7e-12 45.0 1.2 1.4e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 FATC domain BTAD PF03704.17 KPI42986.1 - 0.011 16.2 1.3 0.04 14.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain NTP_transf_7 PF07984.12 KPI42986.1 - 0.062 12.5 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase Dopey_N PF04118.14 KPI42986.1 - 0.26 10.3 3.6 4.1 6.4 0.3 3.1 4 0 0 4 4 4 0 Dopey, N-terminal TPR_14 PF13428.6 KPI42986.1 - 1.2 10.2 7.1 19 6.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat SMK-1 PF04802.15 KPI42987.1 - 7.3e-77 257.5 0.7 7.3e-77 257.5 0.7 1.6 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 MIP-T3 PF10243.9 KPI42987.1 - 0.19 11.7 0.5 2.1 8.4 0.1 2.8 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 CH-like domain DpnI_C PF17726.1 KPI42987.1 - 0.46 10.6 4.6 1 9.5 0.2 2.8 2 0 0 2 2 2 0 Dam-replacing HTH domain DUF3602 PF12223.8 KPI42988.1 - 2.2e-23 82.6 8.9 2.4e-20 72.9 1.2 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) FXMRP1_C_core PF12235.8 KPI42988.1 - 0.87 10.2 4.7 0.35 11.5 1.9 1.6 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal Aim21 PF11489.8 KPI42989.1 - 5e-177 591.0 65.0 5e-177 591.0 65.0 3.5 3 1 0 3 3 3 1 Altered inheritance of mitochondria protein 21 ATG2_CAD PF13329.6 KPI42989.1 - 1.5e-32 112.5 0.0 3.8e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KPI42989.1 - 2.5e-30 104.7 0.7 6.8e-30 103.3 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain RNA_pol_Rpb4 PF03874.16 KPI42990.1 - 4.3e-08 33.5 0.1 0.00037 20.8 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 MMPL PF03176.15 KPI42990.1 - 0.23 10.3 0.9 0.35 9.7 0.9 1.2 1 0 0 1 1 1 0 MMPL family PseudoU_synth_1 PF01416.20 KPI42991.1 - 3.7e-33 114.2 0.0 7.4e-32 110.0 0.0 2.5 2 1 0 2 2 2 1 tRNA pseudouridine synthase Med12 PF09497.10 KPI42992.1 - 6e-24 84.1 0.1 2.1e-23 82.4 0.1 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 AAA PF00004.29 KPI42993.1 - 3.1e-36 124.7 0.0 8e-36 123.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI42993.1 - 1.9e-08 34.0 0.0 4.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KPI42993.1 - 7.1e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI42993.1 - 1.3e-05 25.6 2.2 0.00041 20.8 0.0 3.1 3 1 1 4 4 3 1 AAA ATPase domain AAA_5 PF07728.14 KPI42993.1 - 2.1e-05 24.5 0.1 0.00014 21.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KPI42993.1 - 2.5e-05 24.3 0.0 5.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KPI42993.1 - 0.00029 21.0 0.0 0.00061 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KPI42993.1 - 0.00038 20.6 0.0 0.00094 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPI42993.1 - 0.00049 20.4 0.1 0.0065 16.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KPI42993.1 - 0.00074 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KPI42993.1 - 0.00097 18.6 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KPI42993.1 - 0.001 19.6 0.2 0.0039 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KPI42993.1 - 0.001 19.4 0.0 0.003 17.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KPI42993.1 - 0.0012 18.5 0.2 0.035 13.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KPI42993.1 - 0.002 17.5 0.0 3.3 7.1 0.0 2.9 2 1 1 3 3 3 2 Bacterial TniB protein AAA_28 PF13521.6 KPI42993.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KPI42993.1 - 0.0057 16.6 0.2 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 KPI42993.1 - 0.015 15.1 0.4 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI42993.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KPI42993.1 - 0.017 15.0 0.2 0.053 13.4 0.1 1.8 2 1 0 2 2 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KPI42993.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KPI42993.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KPI42993.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 KPI42993.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KPI42993.1 - 0.039 14.5 0.0 0.084 13.4 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 KPI42993.1 - 0.039 13.1 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KPI42993.1 - 0.053 13.4 0.0 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KPI42993.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KPI42993.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KPI42993.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2721 PF11026.8 KPI42994.1 - 0.0083 16.0 2.2 0.017 15.0 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Ribosomal_L31e PF01198.19 KPI42995.1 - 7e-24 83.9 1.2 1.6e-23 82.7 0.5 2.0 2 1 0 2 2 2 1 Ribosomal protein L31e Ycf1 PF05758.12 KPI42996.1 - 0.1 10.5 0.4 0.19 9.6 0.4 1.3 1 0 0 1 1 1 0 Ycf1 Beta-lactamase PF00144.24 KPI42997.1 - 6.7e-38 130.7 0.0 1.2e-37 129.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KPI42997.1 - 0.0084 15.6 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase JAB PF01398.21 KPI42998.1 - 1.9e-14 53.7 0.0 6.3e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KPI42998.1 - 8.1e-09 35.7 0.1 1.5e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KPI42998.1 - 1.1e-05 25.1 0.1 5.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain E1-E2_ATPase PF00122.20 KPI43000.1 - 1.1e-39 135.9 14.3 4.2e-33 114.4 0.1 3.5 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPI43000.1 - 4.8e-23 81.8 7.9 4.8e-23 81.8 7.9 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPI43000.1 - 3e-20 73.4 0.0 2.7e-18 67.0 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KPI43000.1 - 4.5e-20 71.5 0.0 8.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KPI43000.1 - 1.1e-14 53.8 0.1 3.4e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI43000.1 - 1.5e-05 24.8 1.2 0.0024 17.6 1.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 KPI43000.1 - 0.09 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term CoA_binding_3 PF13727.6 KPI43000.1 - 1.2 9.1 10.5 1.5 8.8 1.4 4.0 4 0 0 4 4 4 0 CoA-binding domain Clr5 PF14420.6 KPI43001.1 - 3.5e-17 62.4 0.9 1.1e-16 60.8 0.9 1.9 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.7 KPI43003.1 - 3.1e-24 85.4 1.1 1.5e-08 35.1 0.2 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI43003.1 - 3.2e-19 69.0 0.5 1.8e-06 28.3 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI43003.1 - 2.6e-15 56.3 2.8 9.8e-06 25.8 0.2 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI43003.1 - 9.5e-15 53.3 0.1 0.005 17.3 0.1 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KPI43003.1 - 1.6e-09 37.8 5.2 0.0038 17.6 0.5 4.9 5 0 0 5 5 5 2 Ankyrin repeat SAP PF02037.27 KPI43004.1 - 2e-08 33.8 0.0 4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain Methyltransf_2 PF00891.18 KPI43005.1 - 6.3e-25 87.7 0.0 9.6e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KPI43005.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KPI43005.1 - 0.059 13.7 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator Dimerisation PF08100.11 KPI43005.1 - 0.065 13.3 0.2 0.19 11.7 0.2 1.9 1 0 0 1 1 1 0 Dimerisation domain MarR PF01047.22 KPI43005.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 MarR family FeoC PF09012.10 KPI43005.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator NAD_binding_8 PF13450.6 KPI43006.1 - 4.5e-11 42.8 0.0 9.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KPI43006.1 - 1.8e-09 36.6 1.3 2.9e-08 32.6 0.1 2.7 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KPI43006.1 - 0.0043 17.1 0.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KPI43006.1 - 0.12 12.0 0.0 0.56 9.7 0.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase POTRA_3 PF17287.2 KPI43007.1 - 0.22 11.0 0.5 0.64 9.5 0.1 1.9 2 0 0 2 2 2 0 POTRA domain zf-CCCH PF00642.24 KPI43007.1 - 0.32 11.0 4.6 0.59 10.1 4.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3460 PF11943.8 KPI43009.1 - 0.52 10.6 4.5 17 5.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3460) BLM_N PF16202.5 KPI43010.1 - 0.23 10.5 0.5 1.2 8.1 0.1 2.0 2 0 0 2 2 2 0 N-terminal region of Bloom syndrome protein EthD PF07110.11 KPI43011.1 - 7.4e-21 75.1 0.2 8.7e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPI43011.1 - 1.4e-06 28.7 0.0 2.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase TAF PF02969.17 KPI43011.1 - 0.099 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF4407 PF14362.6 KPI43014.1 - 0.2 10.9 8.0 0.045 13.1 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ran_BP1 PF00638.18 KPI43015.1 - 5.4e-20 71.9 0.2 5.6e-11 42.8 0.3 2.3 2 0 0 2 2 2 2 RanBP1 domain CwfJ_C_2 PF04676.14 KPI43016.1 - 4.5e-28 98.0 0.2 1.1e-27 96.8 0.2 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KPI43016.1 - 2.8e-26 91.8 0.0 4.8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GST_N_2 PF13409.6 KPI43016.1 - 3.3e-07 30.5 0.0 8.1e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI43016.1 - 3.2e-06 27.5 0.0 1.4e-05 25.4 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FumaraseC_C PF10415.9 KPI43016.1 - 0.31 11.5 1.1 28 5.2 0.1 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Lactonase PF10282.9 KPI43017.1 - 4.4e-26 92.0 0.2 2.7e-25 89.4 0.2 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KPI43017.1 - 0.018 14.6 0.0 0.12 12.0 0.0 2.3 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region ZZ PF00569.17 KPI43018.1 - 3e-10 39.7 3.9 5.4e-10 38.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KPI43018.1 - 3.1e-08 33.7 0.1 3.1e-08 33.7 0.1 3.5 5 0 0 5 5 5 1 Myb-like DNA-binding domain SWIRM PF04433.17 KPI43018.1 - 2e-06 28.0 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain BRF1 PF07741.13 KPI43018.1 - 0.38 11.1 13.2 2 8.8 1.1 4.1 4 0 0 4 4 4 0 Brf1-like TBP-binding domain PP2C PF00481.21 KPI43019.1 - 3.5e-27 95.7 0.0 9.2e-27 94.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Spindle_Spc25 PF08234.12 KPI43020.1 - 1.2e-11 44.6 0.3 8.6e-11 41.9 0.0 2.5 2 1 2 4 4 4 1 Chromosome segregation protein Spc25 HAUS5 PF14817.6 KPI43020.1 - 0.0003 19.7 7.0 0.00034 19.5 7.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF4407 PF14362.6 KPI43020.1 - 0.0092 15.4 14.4 0.013 14.9 14.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) OmpH PF03938.14 KPI43020.1 - 0.023 15.0 20.2 0.095 13.0 20.3 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GBP_C PF02841.14 KPI43020.1 - 0.034 13.5 13.6 0.051 13.0 13.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain IFT57 PF10498.9 KPI43020.1 - 0.058 12.4 11.7 0.068 12.1 11.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SpoIISA_toxin PF14171.6 KPI43020.1 - 0.12 12.1 4.3 0.16 11.6 4.3 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Macoilin PF09726.9 KPI43020.1 - 0.14 10.7 14.0 0.18 10.3 14.0 1.1 1 0 0 1 1 1 0 Macoilin family PspA_IM30 PF04012.12 KPI43020.1 - 0.16 11.5 20.2 0.39 10.2 20.2 1.5 1 1 0 1 1 1 0 PspA/IM30 family FlaC_arch PF05377.11 KPI43020.1 - 0.38 11.2 8.6 5.5 7.5 2.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 KPI43020.1 - 0.56 8.7 7.6 0.72 8.3 7.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KPI43020.1 - 1 7.2 6.2 1.2 7.0 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KPI43020.1 - 1.2 9.3 14.1 1.6 9.0 0.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fungal_TACC PF12709.7 KPI43020.1 - 1.3 9.6 11.6 0.3 11.6 2.2 2.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF724 PF05266.14 KPI43020.1 - 1.5 8.6 10.2 2.4 7.9 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KPI43020.1 - 1.6 8.8 23.9 2.5 8.2 23.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.11 KPI43020.1 - 1.9 8.0 10.1 2.8 7.5 10.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ThiD2 PF17792.1 KPI43020.1 - 2.1 8.8 9.1 13 6.2 9.3 2.1 1 1 0 1 1 1 0 ThiD2 family Presenilin PF01080.17 KPI43020.1 - 2.1 7.0 4.7 2.5 6.8 4.7 1.1 1 0 0 1 1 1 0 Presenilin FliD_C PF07195.12 KPI43020.1 - 2.3 7.6 15.4 5.1 6.5 15.0 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TMPIT PF07851.13 KPI43020.1 - 3.1 6.9 14.1 4.1 6.6 14.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein ApoO PF09769.9 KPI43020.1 - 3.5 7.6 6.6 11 6.0 0.0 2.4 1 1 0 2 2 2 0 Apolipoprotein O COG2 PF06148.11 KPI43020.1 - 4.1 7.5 12.7 5.2 7.2 3.1 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 KPI43020.1 - 4.5 7.8 20.8 0.15 12.6 0.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KPI43020.1 - 7.6 7.5 19.3 7.1 7.6 13.4 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Pex24p PF06398.11 KPI43021.1 - 1.8e-56 191.8 14.8 6.5e-56 189.9 14.8 1.7 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DnaJ PF00226.31 KPI43022.1 - 3.3e-17 62.4 0.5 3.3e-17 62.4 0.5 1.7 2 0 0 2 2 2 1 DnaJ domain CotJB PF12652.7 KPI43022.1 - 0.12 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 CotJB protein Noc2 PF03715.13 KPI43023.1 - 1.7e-18 66.9 0.1 2.1e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Noc2p family Epimerase PF01370.21 KPI43024.1 - 6.5e-20 71.6 0.0 8.6e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI43024.1 - 3.1e-13 49.4 0.0 5.4e-13 48.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KPI43024.1 - 2.1e-09 37.3 0.5 5.4e-09 35.9 0.5 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KPI43024.1 - 2.5e-08 34.0 0.2 4.3e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPI43024.1 - 3.1e-08 33.1 0.0 0.0033 16.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 KPI43024.1 - 1.1e-06 28.8 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KPI43024.1 - 0.00034 20.3 0.1 0.0022 17.6 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 KPI43024.1 - 0.00044 19.4 0.1 0.00078 18.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KPI43024.1 - 0.00079 18.9 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Mannosidase_ig PF17786.1 KPI43025.1 - 4.3e-17 62.5 0.2 9.9e-17 61.3 0.2 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KPI43025.1 - 2e-10 41.3 0.0 6.2e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 RRM_1 PF00076.22 KPI43026.1 - 1.6e-45 152.8 0.1 4.5e-17 61.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI43026.1 - 2.1e-29 101.2 0.0 4.2e-20 71.4 0.0 4.5 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KPI43026.1 - 1.5e-06 28.1 0.2 0.58 10.2 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 KPI43026.1 - 6.9e-05 23.4 3.5 0.043 14.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat RRM_7 PF16367.5 KPI43026.1 - 0.00074 19.6 0.0 0.014 15.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif Lsm_interact PF05391.11 KPI43026.1 - 0.022 14.2 0.1 0.074 12.6 0.1 2.0 1 0 0 1 1 1 0 Lsm interaction motif RRM_Rrp7 PF17799.1 KPI43026.1 - 0.027 14.3 0.0 3 7.6 0.0 2.6 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF1866 PF08952.11 KPI43026.1 - 0.037 13.9 0.0 9.9 6.0 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1866) Cupin_2 PF07883.11 KPI43027.1 - 1.6e-06 27.7 0.1 3.6e-06 26.6 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Tubulin_C PF03953.17 KPI43028.1 - 0.06 13.5 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Tubulin C-terminal domain zf-U1 PF06220.12 KPI43029.1 - 1.1e-21 76.3 2.6 1.5e-21 75.8 2.6 1.2 1 0 0 1 1 1 1 U1 zinc finger DUF5388 PF17363.2 KPI43029.1 - 0.058 13.6 0.0 0.078 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Sarcoglycan_1 PF04790.13 KPI43030.1 - 0.56 9.5 4.7 5.3 6.3 0.2 2.4 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein F_bP_aldolase PF01116.20 KPI43031.1 - 1.6e-94 316.5 0.1 1.9e-94 316.3 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ost5 PF05251.12 KPI43032.1 - 7.9e-18 64.5 5.4 9e-18 64.3 5.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 VPDSG-CTERM PF18205.1 KPI43032.1 - 0.091 12.6 3.9 0.091 12.6 3.9 1.8 2 0 0 2 2 2 0 VPDSG-CTERM motif ADH_N PF08240.12 KPI43033.1 - 1.3e-20 73.3 0.2 2.6e-20 72.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI43033.1 - 1.1e-12 48.1 0.1 7.1e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI43033.1 - 0.0044 18.1 0.0 0.0079 17.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI43033.1 - 0.059 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Fungal_trans PF04082.18 KPI43034.1 - 1.1e-13 50.8 0.2 1.4e-13 50.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Band_7 PF01145.25 KPI43035.1 - 9.9e-28 97.3 1.9 9.9e-28 97.3 1.9 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Fungal_trans PF04082.18 KPI43036.1 - 7.6e-23 80.9 0.4 2.5e-22 79.2 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain CENP-B_dimeris PF09026.10 KPI43037.1 - 0.59 10.5 8.1 1.6 9.2 8.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KPI43037.1 - 1.8 7.8 4.7 3.6 6.8 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein HIT PF01230.23 KPI43038.1 - 7.3e-21 74.7 0.4 1.2e-20 74.1 0.4 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KPI43038.1 - 5.4e-14 52.6 0.0 8.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KPI43038.1 - 3.1e-07 30.3 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 KPI43039.1 - 1.3e-49 165.8 0.0 3.7e-17 61.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KPI43039.1 - 0.002 18.2 0.1 5.4 7.2 0.0 4.0 3 2 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 KPI43039.1 - 0.0034 17.0 0.0 0.36 10.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPI43039.1 - 0.0055 16.7 0.0 8.6 6.5 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif GRP PF07172.11 KPI43039.1 - 0.014 16.0 15.3 0.014 16.0 15.3 4.6 4 1 1 5 5 5 0 Glycine rich protein family SPOR PF05036.13 KPI43039.1 - 0.015 15.7 0.2 6.9 7.1 0.0 3.4 3 0 0 3 3 3 0 Sporulation related domain RRM_Rrp7 PF17799.1 KPI43039.1 - 0.022 14.6 0.0 3.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain ATP-grasp_2 PF08442.10 KPI43039.1 - 0.023 14.3 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain PknH_C PF14032.6 KPI43039.1 - 0.037 13.9 0.4 19 5.0 0.1 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_occluded PF16842.5 KPI43039.1 - 0.083 12.8 0.0 17 5.3 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif MFS_1 PF07690.16 KPI43040.1 - 1.4e-42 146.0 32.5 1.4e-42 146.0 32.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI43040.1 - 2.5e-10 39.5 2.2 3.9e-10 38.8 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPI43040.1 - 3.4e-10 39.4 5.2 3.4e-10 39.4 5.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2178 PF09946.9 KPI43040.1 - 0.27 11.4 8.1 0.31 11.2 1.2 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) Ran_BP1 PF00638.18 KPI43041.1 - 5.7e-09 36.3 0.0 1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KPI43041.1 - 6.3e-05 23.6 0.9 6.3e-05 23.6 0.9 8.7 8 2 0 8 8 8 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG PF13634.6 KPI43041.1 - 0.013 16.3 18.4 0.013 16.3 18.4 13.9 5 3 6 11 11 11 0 Nucleoporin FG repeat region Nop14 PF04147.12 KPI43041.1 - 3.1 5.9 23.1 4.9 5.2 23.1 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.16 KPI43042.1 - 1.3e-29 103.2 30.4 1.2e-27 96.8 11.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI43042.1 - 4.2e-13 49.0 1.0 4.2e-13 49.0 1.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4307 PF14155.6 KPI43042.1 - 0.48 10.3 1.9 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) FMN_dh PF01070.18 KPI43043.1 - 3.5e-75 253.2 0.0 4.3e-54 183.9 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPI43043.1 - 5.8e-16 58.4 0.1 2.2e-15 56.6 0.0 2.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KPI43043.1 - 8.2e-05 21.9 0.1 0.00013 21.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPI43043.1 - 0.0001 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPI43043.1 - 0.099 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 KPI43043.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family adh_short PF00106.25 KPI43044.1 - 1e-15 57.7 0.0 5e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43044.1 - 2.9e-09 36.9 0.0 3.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI43044.1 - 1.5e-05 25.0 1.0 1.8e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Muted PF14942.6 KPI43045.1 - 0.12 12.8 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein PIRT PF15099.6 KPI43045.1 - 0.14 11.7 0.2 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Pribosyltran PF00156.27 KPI43046.1 - 3.5e-14 52.6 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KPI43046.1 - 0.024 14.1 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Fungal_trans PF04082.18 KPI43047.1 - 1.5e-10 40.6 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KPI43048.1 - 2.4e-32 112.0 0.0 4.4e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43048.1 - 5.6e-30 104.6 0.0 8.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TFIIB PF00382.19 KPI43048.1 - 5.2e-22 77.7 0.0 4.1e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KPI43048.1 - 7.7e-18 64.7 0.5 7.7e-18 64.7 0.5 3.3 2 2 1 3 3 3 1 Brf1-like TBP-binding domain KR PF08659.10 KPI43048.1 - 1.3e-07 31.7 0.0 1.1e-06 28.8 0.0 2.4 1 1 0 1 1 1 1 KR domain DUF4023 PF13215.6 KPI43048.1 - 0.022 14.8 0.5 0.022 14.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) THF_DHG_CYH_C PF02882.19 KPI43048.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.25 KPI43049.1 - 1.6e-69 234.2 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43049.1 - 5.6e-33 114.3 0.0 8.4e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KPI43049.1 - 1.5e-09 38.4 0.8 5.2e-09 36.7 0.2 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KPI43049.1 - 8.3e-06 25.0 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KPI43049.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Glyco_transf_20 PF00982.21 KPI43050.1 - 2.4e-194 646.4 0.0 2.8e-194 646.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 LNP1 PF15419.6 KPI43050.1 - 0.067 13.4 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 DJ-1_PfpI PF01965.24 KPI43051.1 - 3.7e-11 43.1 0.0 5.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family NifU_N PF01592.16 KPI43051.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 NifU-like N terminal domain zf_CCCH_4 PF18345.1 KPI43052.1 - 5.7e-05 23.0 2.3 0.0001 22.2 2.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KPI43052.1 - 0.00045 20.1 2.3 0.00079 19.3 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KPI43052.1 - 0.0063 16.3 0.9 0.011 15.5 0.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KPI43052.1 - 0.02 15.6 0.1 0.12 13.1 0.1 2.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 KPI43052.1 - 0.032 14.4 1.4 0.077 13.2 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger containing family AT_hook PF02178.19 KPI43052.1 - 0.18 11.8 3.7 0.7 10.0 3.7 2.1 1 0 0 1 1 1 0 AT hook motif zf-CCCH_2 PF14608.6 KPI43052.1 - 0.3 11.6 2.6 0.65 10.5 2.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Glyco_hydro_18 PF00704.28 KPI43053.1 - 6.5e-88 295.4 5.6 7.6e-88 295.2 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RSN1_7TM PF02714.15 KPI43054.1 - 3.3e-86 289.0 22.9 3.3e-86 289.0 22.9 2.5 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KPI43054.1 - 3.9e-43 146.9 2.8 3.9e-43 146.9 2.8 3.2 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KPI43054.1 - 7.4e-34 117.5 1.7 1.2e-33 116.8 1.7 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KPI43054.1 - 3.8e-14 52.6 0.5 1e-13 51.3 0.5 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KPI43054.1 - 0.026 14.4 0.5 0.23 11.3 0.5 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIPSNAP PF07978.13 KPI43055.1 - 8.6e-40 135.1 0.4 6.8e-28 96.9 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP ubiquitin PF00240.23 KPI43056.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KPI43056.1 - 0.1 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF936 PF06075.12 KPI43056.1 - 3.3 6.5 11.9 5.3 5.8 11.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DIOX_N PF14226.6 KPI43057.1 - 9.4e-31 107.0 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI43057.1 - 1.1e-21 77.2 0.0 1.8e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 KPI43058.1 - 1.5e-41 140.1 0.6 1.4e-19 69.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KPI43058.1 - 1.3e-19 71.1 0.1 1.3e-19 71.1 0.1 3.2 4 1 0 4 4 4 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KPI43058.1 - 4.1e-05 23.4 0.0 0.51 10.2 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif CDC45 PF02724.14 KPI43058.1 - 0.068 11.4 7.2 0.11 10.8 7.2 1.3 1 0 0 1 1 1 0 CDC45-like protein RRM_5 PF13893.6 KPI43058.1 - 0.098 12.3 0.0 0.36 10.4 0.0 2.0 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPI43058.1 - 0.25 11.4 0.0 0.25 11.4 0.0 3.1 4 1 0 4 4 4 0 RNA binding motif PHM7_cyt PF14703.6 KPI43058.1 - 2 8.6 8.7 14 5.9 0.0 3.8 4 0 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DUF3425 PF11905.8 KPI43060.1 - 2.7e-13 50.0 0.0 6.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Lipase_GDSL_2 PF13472.6 KPI43061.1 - 5.6e-12 46.4 0.0 1.3e-11 45.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KPI43061.1 - 6e-06 26.4 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase PHP PF02811.19 KPI43062.1 - 3.1e-14 53.6 0.0 8e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 PHP domain WSC PF01822.19 KPI43064.1 - 6.5e-14 51.9 12.4 6.5e-14 51.9 12.4 3.1 3 0 0 3 3 3 2 WSC domain FSA_C PF10479.9 KPI43064.1 - 8.2 4.4 6.5 12 3.9 6.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Lactamase_B_2 PF12706.7 KPI43066.1 - 1e-26 93.7 0.0 6.6e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI43066.1 - 6.1e-09 36.0 0.0 1.4e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPI43066.1 - 0.089 12.8 0.7 0.56 10.2 0.5 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Apt1 PF10351.9 KPI43067.1 - 1.3 7.8 8.4 1.4 7.7 8.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ORC6 PF05460.13 KPI43067.1 - 2.8 7.1 12.9 3.2 6.9 12.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4674 PF15719.5 KPI43067.1 - 7.5 6.5 14.0 0.87 9.6 6.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) ECF_trnsprt PF12822.7 KPI43069.1 - 1.3 9.1 9.8 0.1 12.7 3.6 1.9 2 0 0 2 2 2 0 ECF transporter, substrate-specific component PARP PF00644.20 KPI43070.1 - 2.3e-57 193.8 0.1 4e-57 193.0 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KPI43070.1 - 7.9e-32 110.2 0.1 1.2e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KPI43070.1 - 8.5e-24 83.4 0.6 1.9e-23 82.3 0.6 1.6 1 0 0 1 1 1 1 WGR domain Fungal_trans PF04082.18 KPI43071.1 - 1.5e-28 99.6 0.0 2.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KPI43072.1 - 1.3e-33 116.1 7.7 3.8e-33 114.6 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43072.1 - 2.8e-24 86.0 0.1 4.7e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI43072.1 - 2.4e-05 24.3 0.2 6.2e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 KR domain DUF4157 PF13699.6 KPI43072.1 - 0.024 14.9 0.4 0.05 13.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) S_layer_C PF05124.12 KPI43073.1 - 0.032 14.2 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region FOXP-CC PF16159.5 KPI43073.1 - 0.31 11.7 2.7 2.3 8.9 0.1 2.4 1 1 0 2 2 2 0 FOXP coiled-coil domain adh_short_C2 PF13561.6 KPI43074.1 - 2.5e-55 187.6 1.0 2.9e-55 187.4 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43074.1 - 2.9e-38 131.3 0.2 3.7e-38 131.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI43074.1 - 2.7e-08 34.0 0.3 4.3e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 KPI43074.1 - 0.0012 18.9 0.2 0.65 10.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase Family 4 YjeF_N PF03853.15 KPI43074.1 - 0.0027 17.6 0.1 0.0058 16.5 0.0 1.6 2 0 0 2 2 2 1 YjeF-related protein N-terminus ADH_zinc_N PF00107.26 KPI43074.1 - 0.082 12.9 0.7 1 9.3 0.0 2.7 2 2 1 3 3 3 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 KPI43074.1 - 0.096 12.0 0.0 0.21 10.9 0.0 1.5 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.12 KPI43074.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein RTA1 PF04479.13 KPI43075.1 - 5.8e-55 186.1 0.0 1.2e-54 185.1 0.0 1.5 1 0 0 1 1 1 1 RTA1 like protein DEAD PF00270.29 KPI43076.1 - 4.8e-46 156.7 0.1 8.3e-46 156.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI43076.1 - 2.2e-27 95.6 0.0 1e-25 90.2 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Phage_integrase PF00589.22 KPI43076.1 - 0.031 14.1 0.1 0.076 12.8 0.1 1.6 1 0 0 1 1 1 0 Phage integrase family AAA_22 PF13401.6 KPI43076.1 - 0.1 12.9 0.2 0.31 11.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.7 KPI43077.1 - 0.0081 16.0 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 F-box-like IN_DBD_C PF00552.21 KPI43077.1 - 0.093 12.0 0.1 2.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Integrase DNA binding domain CBFD_NFYB_HMF PF00808.23 KPI43078.1 - 9.1e-06 25.9 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KPI43078.1 - 0.0012 19.2 0.3 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 KPI43078.1 - 0.0031 17.6 11.0 0.0051 16.9 11.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 KPI43078.1 - 0.52 10.3 10.4 1 9.4 10.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 KPI43078.1 - 3.2 7.1 24.2 5 6.4 24.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KPI43078.1 - 4.5 5.3 23.3 6.1 4.9 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M14 PF00246.24 KPI43079.1 - 1.6e-78 264.5 0.0 3.3e-78 263.4 0.0 1.5 1 1 1 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KPI43079.1 - 0.16 12.4 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 Carboxypeptidase activation peptide CC2-LZ PF16516.5 KPI43080.1 - 0.003 17.9 2.0 0.17 12.3 0.1 2.7 2 0 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BBP1_C PF15272.6 KPI43080.1 - 0.027 14.3 5.8 0.066 13.0 5.8 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TMF_TATA_bd PF12325.8 KPI43080.1 - 0.05 13.8 4.9 0.17 12.1 4.9 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KPI43080.1 - 0.076 12.4 8.2 0.16 11.3 8.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mt_ATP-synt_B PF05405.14 KPI43080.1 - 0.12 12.0 3.6 0.27 10.8 3.6 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Prefoldin_2 PF01920.20 KPI43080.1 - 0.7 9.9 10.9 6.3 6.8 0.6 3.2 3 0 0 3 3 3 0 Prefoldin subunit Malate_DH PF12434.8 KPI43080.1 - 0.79 9.8 0.0 0.79 9.8 0.0 2.7 3 0 0 3 3 3 0 Malate dehydrogenase enzyme DUF4404 PF14357.6 KPI43080.1 - 2 9.1 5.5 2.4 8.8 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF641 PF04859.12 KPI43080.1 - 3.7 7.9 8.9 2 8.7 0.8 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 KPI43080.1 - 6.6 7.4 7.5 15 6.3 4.2 2.6 1 1 1 2 2 2 0 SlyX GEN1_C PF18380.1 KPI43081.1 - 4.6e-17 62.8 0.6 1.1e-16 61.6 0.6 1.7 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain TPR_19 PF14559.6 KPI43082.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI43082.1 - 0.31 12.0 4.2 0.55 11.2 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BRCT PF00533.26 KPI43083.1 - 4.1e-13 49.5 0.0 1e-12 48.2 0.0 1.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain ALG11_N PF15924.5 KPI43084.1 - 9.1e-81 270.9 0.0 1.4e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KPI43084.1 - 2.7e-20 72.6 0.0 4.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPI43084.1 - 3.2e-10 40.6 0.0 1.1e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPI43084.1 - 0.0052 16.8 0.2 0.01 15.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 CFEM PF05730.11 KPI43085.1 - 6.3e-12 45.4 10.9 1.1e-11 44.7 10.9 1.4 1 0 0 1 1 1 1 CFEM domain NIF PF03031.18 KPI43086.1 - 6.5e-54 181.9 0.1 9.2e-54 181.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase adh_short PF00106.25 KPI43087.1 - 1.4e-40 138.9 2.5 2e-40 138.4 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43087.1 - 1.6e-26 93.3 3.3 6.7e-26 91.3 2.4 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI43087.1 - 1.9e-12 47.5 1.1 3.8e-12 46.5 1.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KPI43087.1 - 1.7e-08 34.0 0.5 2.3e-08 33.5 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 KPI43087.1 - 0.14 11.9 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.22 KPI43088.1 - 5e-37 127.7 0.0 6.2e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TEA PF01285.18 KPI43089.1 - 1.6e-27 95.4 0.1 3.4e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Ribosomal_L22 PF00237.19 KPI43091.1 - 3.4e-22 78.6 0.1 2.4e-21 75.9 0.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L22p/L17e CENP-Q PF13094.6 KPI43091.1 - 0.025 14.8 8.1 0.031 14.5 4.0 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit NmrA PF05368.13 KPI43092.1 - 1.6e-25 90.0 0.2 8.2e-25 87.7 0.2 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI43092.1 - 3.2e-17 63.0 0.0 7.8e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI43092.1 - 5.7e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HSP70 PF00012.20 KPI43092.1 - 2.8e-06 25.8 0.1 0.00069 17.9 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein Sacchrp_dh_NADP PF03435.18 KPI43092.1 - 0.0034 17.6 0.7 0.033 14.4 0.1 2.7 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KPI43092.1 - 0.025 13.6 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.8 KPI43092.1 - 0.068 12.9 0.3 13 5.6 0.0 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DapB_N PF01113.20 KPI43092.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KPI43092.1 - 0.14 12.6 0.1 0.35 11.3 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Noc2 PF03715.13 KPI43093.1 - 9.3e-80 268.1 0.2 9.3e-80 268.1 0.2 1.7 2 0 0 2 2 2 1 Noc2p family XPC-binding PF09280.11 KPI43093.1 - 0.011 15.5 0.2 8.4 6.2 0.0 3.0 3 0 0 3 3 3 0 XPC-binding domain TENA_THI-4 PF03070.16 KPI43093.1 - 0.024 14.4 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 TENA/THI-4/PQQC family DUF5107 PF17128.4 KPI43093.1 - 0.058 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) Homeodomain PF00046.29 KPI43094.1 - 2.5e-17 62.4 0.8 4.9e-16 58.3 1.4 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KPI43094.1 - 0.002 18.0 0.2 0.0068 16.3 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Coatomer_WDAD PF04053.14 KPI43095.1 - 9.2e-149 496.3 0.0 1.6e-148 495.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KPI43095.1 - 6.7e-19 67.9 9.8 9e-05 23.2 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI43095.1 - 6.4e-05 23.2 0.1 0.86 9.9 0.0 4.5 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI43095.1 - 0.0014 17.4 0.2 0.19 10.3 0.1 3.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 TPR_19 PF14559.6 KPI43095.1 - 0.043 14.3 0.7 4.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI43095.1 - 0.16 12.6 4.8 5.8 7.8 0.4 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI43095.1 - 0.58 11.1 3.7 5.6 8.1 0.1 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 KPI43096.1 - 1.2e-57 195.3 21.0 6.5e-55 186.4 21.0 2.3 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KPI43096.1 - 7.2e-36 124.1 0.0 1.3e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KPI43096.1 - 2e-35 121.8 0.4 2e-35 121.8 0.4 1.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF588 PF04535.12 KPI43096.1 - 0.017 14.9 4.5 0.31 10.8 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF588) DUF1192 PF06698.11 KPI43096.1 - 0.045 13.8 0.8 0.094 12.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TMF_TATA_bd PF12325.8 KPI43096.1 - 0.11 12.8 0.2 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sec16 PF12932.7 KPI43096.1 - 0.13 12.9 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF2768 PF10966.8 KPI43096.1 - 0.25 11.8 3.0 1.1 9.8 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) ABC_tran_CTD PF16326.5 KPI43096.1 - 0.38 11.0 3.5 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain GCV_T PF01571.21 KPI43097.1 - 4.9e-75 252.2 0.0 5.1e-47 160.4 0.0 2.1 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KPI43097.1 - 4.1e-16 58.7 1.9 4.3e-16 58.6 0.3 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain RTA1 PF04479.13 KPI43098.1 - 3.8e-65 219.4 7.7 4.9e-65 219.0 7.7 1.1 1 0 0 1 1 1 1 RTA1 like protein PMT_4TMC PF16192.5 KPI43098.1 - 0.13 11.8 2.2 8.7 5.9 0.0 2.5 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Pam17 PF08566.10 KPI43098.1 - 0.2 11.5 0.3 0.86 9.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF1761 PF08570.10 KPI43098.1 - 0.2 11.9 5.8 0.92 9.8 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) SHR3_chaperone PF08229.11 KPI43098.1 - 1.5 7.8 4.8 5.5 5.9 0.5 2.3 2 0 0 2 2 2 0 ER membrane protein SH3 Abhydrolase_1 PF00561.20 KPI43100.1 - 3e-18 66.4 0.0 1.3e-14 54.5 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI43100.1 - 8.3e-12 46.2 0.0 1.1e-11 45.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI43100.1 - 1.3e-10 41.0 0.0 2.1e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KPI43100.1 - 1.7e-09 37.8 0.0 0.015 15.1 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase DLH PF01738.18 KPI43100.1 - 3.5e-05 23.5 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPI43100.1 - 5.6e-05 22.7 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 KPI43100.1 - 0.046 12.4 0.0 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 Ndr family Not1 PF04054.15 KPI43101.1 - 1.1e-88 297.7 0.0 3.2e-88 296.1 0.0 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KPI43101.1 - 3.9e-84 281.5 2.4 6.8e-84 280.7 1.3 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KPI43101.1 - 1.4e-45 154.8 1.8 1.4e-45 154.8 1.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KPI43101.1 - 2e-39 134.7 0.0 4.4e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KPI43101.1 - 2.9e-18 66.4 0.0 1e-17 64.6 0.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Transglut_i_TM PF14400.6 KPI43101.1 - 1.8 8.6 4.5 5 7.2 0.1 3.0 3 0 0 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices GFO_IDH_MocA PF01408.22 KPI43102.1 - 1.1e-24 87.6 0.0 1.6e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KPI43102.1 - 0.03 14.9 0.0 0.1 13.2 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2013 PF09431.10 KPI43103.1 - 4.9e-54 182.2 1.6 9.3e-54 181.3 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) NopRA1 PF16201.5 KPI43103.1 - 0.017 14.7 0.0 0.058 13.0 0.0 1.9 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 MFS_1 PF07690.16 KPI43104.1 - 9.3e-29 100.4 42.6 1.7e-28 99.6 41.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI43104.1 - 0.0023 17.3 28.1 0.0032 16.8 28.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4418 PF14387.6 KPI43104.1 - 6.4 7.0 10.2 6.2 7.1 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Porin_3 PF01459.22 KPI43105.1 - 9.3e-68 228.6 9.3 2.4e-67 227.2 9.3 1.6 1 1 0 1 1 1 1 Eukaryotic porin OpcA PF07239.11 KPI43105.1 - 0.03 14.0 0.3 0.069 12.8 0.2 1.6 1 1 0 1 1 1 0 Outer membrane protein OpcA DAP10 PF07213.11 KPI43106.1 - 0.0049 16.8 0.4 0.012 15.6 0.4 1.5 1 0 0 1 1 1 1 DAP10 membrane protein TMEM154 PF15102.6 KPI43106.1 - 0.013 15.4 0.3 0.034 14.0 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family LPG_synthase_TM PF03706.13 KPI43106.1 - 0.036 13.6 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SfLAP PF11139.8 KPI43106.1 - 0.06 12.8 0.6 0.45 9.9 0.0 2.4 3 0 0 3 3 3 0 Sap, sulfolipid-1-addressing protein EphA2_TM PF14575.6 KPI43106.1 - 0.17 12.8 0.0 0.48 11.3 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KPI43106.1 - 0.17 11.4 0.1 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 CD34/Podocalyxin family Apt1 PF10351.9 KPI43106.1 - 0.2 10.5 2.4 0.36 9.6 2.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1294 PF06961.13 KPI43106.1 - 1.1 9.6 2.9 8.5 6.7 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) DUF202 PF02656.15 KPI43106.1 - 1.8 9.1 5.1 1.1 9.8 0.6 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF202) EBP PF05241.12 KPI43107.1 - 1e-47 161.9 15.5 1.2e-47 161.6 15.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF1601 PF07671.11 KPI43107.1 - 0.21 11.5 0.7 0.6 10.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) Cupin_5 PF06172.11 KPI43109.1 - 4.5e-38 130.6 0.0 5.6e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) HIM1 PF08732.10 KPI43110.1 - 4e-09 36.2 0.0 5.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 KPI43110.1 - 1.3e-06 28.4 0.0 2.3e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPI43110.1 - 5.2e-06 26.9 0.0 1.2e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KPI43110.1 - 9.3e-05 22.0 0.0 0.0006 19.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1471 PF07338.13 KPI43110.1 - 0.0018 18.2 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) NmrA PF05368.13 KPI43110.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GCIP PF13324.6 KPI43111.1 - 2.1e-18 66.9 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting PMC2NT PF08066.12 KPI43111.1 - 0.033 14.9 0.0 13 6.6 0.0 3.2 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Suppressor_P21 PF11479.8 KPI43111.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain p450 PF00067.22 KPI43112.1 - 5.1e-46 157.4 0.0 6.6e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.20 KPI43113.1 - 5.7e-18 65.3 0.0 9.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KPI43113.1 - 5.4e-17 62.6 0.0 8.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PNP_UDP_1 PF01048.20 KPI43114.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 KPI43115.1 - 3.5e-24 85.2 0.4 1.2e-07 32.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI43115.1 - 9.3e-22 76.8 1.3 1.1e-05 25.7 0.1 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KPI43115.1 - 1.1e-21 76.3 1.6 2.3e-05 24.6 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KPI43115.1 - 6.7e-20 71.2 0.7 5.4e-08 33.2 0.0 4.0 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI43115.1 - 2.1e-17 61.4 1.7 0.0033 17.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat NDT80_PhoG PF05224.12 KPI43116.1 - 7e-36 124.2 0.9 1.1e-35 123.6 0.9 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF383 PF04063.14 KPI43117.1 - 7.4e-56 188.8 0.0 3.3e-55 186.7 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KPI43117.1 - 1.7e-22 79.0 1.1 4e-22 77.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Rhodanese PF00581.20 KPI43118.1 - 1.4e-05 25.6 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Rhomboid_N PF12122.8 KPI43118.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease adh_short_C2 PF13561.6 KPI43120.1 - 1.5e-43 149.0 0.0 1.8e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43120.1 - 1.2e-41 142.3 0.0 1.5e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI43120.1 - 1.7e-07 31.3 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI43120.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI43120.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Fasciclin PF02469.22 KPI43121.1 - 1.2e-23 83.7 0.0 3.5e-12 46.7 0.0 2.4 2 1 0 2 2 2 2 Fasciclin domain SKG6 PF08693.10 KPI43121.1 - 0.016 14.6 1.6 0.034 13.6 1.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KPI43121.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rax2 PF12768.7 KPI43121.1 - 0.043 13.3 0.2 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF4448 PF14610.6 KPI43121.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1996 PF09362.10 KPI43122.1 - 1.8e-86 289.9 4.0 2.6e-86 289.4 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KPI43122.1 - 1.1e-35 121.7 26.6 3e-19 69.0 9.1 3.2 2 0 0 2 2 2 2 WSC domain Glyco_hydro_47 PF01532.20 KPI43123.1 - 1.1e-182 608.0 0.6 1.3e-182 607.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ERCC4 PF02732.15 KPI43124.1 - 5.6e-28 98.1 1.0 9.7e-28 97.3 0.4 1.8 2 0 0 2 2 2 1 ERCC4 domain DUF4269 PF14091.6 KPI43124.1 - 0.075 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) adh_short PF00106.25 KPI43125.1 - 2.5e-21 76.0 0.2 1.8e-18 66.7 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43125.1 - 7.2e-12 45.4 0.4 5.9e-08 32.6 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI43125.1 - 1e-07 32.0 0.2 1.4e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 KR domain FKBP_C PF00254.28 KPI43126.1 - 9.4e-28 96.4 0.1 1.1e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 KPI43126.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 BDBT FKBP like N-terminal Nitroreductase PF00881.24 KPI43127.1 - 1.2e-14 54.7 0.0 1.4e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Retinin_C PF04527.12 KPI43127.1 - 0.1 12.8 0.5 0.21 11.9 0.5 1.4 1 0 0 1 1 1 0 Drosophila Retinin like protein ThrE PF06738.12 KPI43128.1 - 4.1e-61 206.4 17.2 2.2e-56 190.9 3.3 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KPI43128.1 - 1.8e-12 47.5 31.5 4.2e-11 43.1 15.5 3.7 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE DUF4743 PF15916.5 KPI43128.1 - 0.076 13.0 0.3 1.6 8.7 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4743) Baculo_E25 PF05274.11 KPI43128.1 - 0.2 11.5 1.9 0.35 10.7 0.1 2.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein E25 Methyltransf_11 PF08241.12 KPI43129.1 - 1.6e-08 35.1 0.0 4.2e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI43129.1 - 2.4e-06 28.2 0.0 7.9e-06 26.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI43129.1 - 0.0016 18.2 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI43129.1 - 0.068 13.9 0.0 0.093 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 KPI43129.1 - 0.093 11.3 0.0 0.18 10.3 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Transmemb_17 PF09799.9 KPI43130.1 - 1.7 9.3 7.2 0.16 12.5 1.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein Acetyltransf_10 PF13673.7 KPI43131.1 - 6.4e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI43131.1 - 0.00011 22.6 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI43131.1 - 0.0027 17.9 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AhpC-TSA PF00578.21 KPI43132.1 - 1.1e-10 41.5 0.0 1.7e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KPI43132.1 - 1.4e-07 31.6 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KPI43132.1 - 3.7e-06 26.7 0.0 0.00015 21.5 0.0 2.0 1 1 0 2 2 2 1 Redoxin DUF2434 PF10361.9 KPI43132.1 - 0.06 12.3 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) MFS_1 PF07690.16 KPI43133.1 - 5e-35 121.1 27.8 7e-35 120.6 27.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PigN PF04987.14 KPI43135.1 - 1.7e-154 515.1 32.4 2.3e-154 514.6 32.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KPI43135.1 - 4.4e-09 36.4 3.2 1.8e-07 31.1 2.9 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KPI43135.1 - 2.1e-07 30.6 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KPI43135.1 - 1.3e-06 28.0 0.1 2.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Solute_trans_a PF03619.16 KPI43136.1 - 7.3e-98 327.3 11.7 8.7e-98 327.1 11.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MAT1 PF06391.13 KPI43136.1 - 0.38 10.5 6.1 0.19 11.5 3.9 1.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 NAD_binding_6 PF08030.12 KPI43137.1 - 2.3e-18 66.8 0.0 4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI43137.1 - 2.4e-16 59.7 0.0 1.1e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KPI43137.1 - 1.4e-12 47.8 2.6 1.4e-12 47.8 2.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component ADP_ribosyl_GH PF03747.14 KPI43138.1 - 2.8e-56 191.4 1.4 3.4e-56 191.1 1.4 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Prenyltrans PF00432.21 KPI43139.1 - 4.2e-17 61.6 14.8 5e-05 23.0 0.0 5.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat DNA_methylase PF00145.17 KPI43140.1 - 9.9e-34 117.2 0.0 1.8e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KPI43140.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KPI43140.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 BAH domain DUF371 PF04027.13 KPI43142.1 - 0.16 12.0 0.0 0.56 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF371) DUF5541 PF17695.1 KPI43143.1 - 0.06 13.8 1.6 0.27 11.7 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5541) SLAC1 PF03595.17 KPI43144.1 - 8.5e-70 235.6 34.7 1.2e-69 235.1 34.7 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel MoeA_N PF03453.17 KPI43144.1 - 8.5e-31 106.8 0.4 1.3e-30 106.2 0.4 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KPI43144.1 - 5.1e-23 81.3 0.0 9.7e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain CPP1-like PF11833.8 KPI43144.1 - 0.24 11.0 3.7 0.12 12.0 0.6 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like YdjM PF04307.14 KPI43145.1 - 1.6 8.0 4.0 2 7.7 4.0 1.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase GPI-anchored PF10342.9 KPI43146.1 - 0.0045 17.7 0.1 0.0045 17.7 0.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KPI43146.1 - 0.21 10.8 10.9 0.22 10.7 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_lid_9 PF17871.1 KPI43147.1 - 0.093 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA lid domain TLP1_add_C PF18313.1 KPI43148.1 - 1.3e-29 101.9 0.0 2.8e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain RHH_1 PF01402.21 KPI43148.1 - 0.025 14.5 0.2 0.058 13.4 0.2 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family HMA PF00403.26 KPI43149.1 - 1.1e-14 54.6 0.4 2e-14 53.8 0.4 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KPI43149.1 - 3.4e-09 37.0 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CIA30 PF08547.12 KPI43150.1 - 4.5e-23 82.0 0.0 3.9e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Transp_cyt_pur PF02133.15 KPI43152.1 - 3.4e-66 223.8 26.0 4.5e-66 223.4 26.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2458 PF10454.9 KPI43153.1 - 9.7e-43 145.8 0.3 1.8e-42 144.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) SusE PF14292.6 KPI43153.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 SusE outer membrane protein AAA_11 PF13086.6 KPI43155.1 - 7.2e-57 193.1 0.0 1.9e-56 191.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KPI43155.1 - 2.5e-49 167.6 0.0 1.7e-46 158.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KPI43155.1 - 4.4e-14 52.6 0.1 2e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KPI43155.1 - 6e-08 33.1 0.0 1.8e-06 28.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 KPI43155.1 - 6.6e-06 25.7 0.0 0.032 13.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KPI43155.1 - 9.2e-06 25.8 0.0 5.2e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KPI43155.1 - 4.6e-05 22.8 0.0 0.076 12.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KPI43155.1 - 0.00044 19.9 0.0 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KPI43155.1 - 0.0029 17.5 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KPI43155.1 - 0.0043 17.3 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KPI43155.1 - 0.0062 16.3 0.1 3.1 7.5 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KPI43155.1 - 0.015 15.7 0.0 0.046 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KPI43155.1 - 0.016 14.8 0.0 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI43155.1 - 0.018 14.7 0.0 0.069 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KPI43155.1 - 0.022 15.2 0.0 0.076 13.4 0.1 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KPI43155.1 - 0.033 13.4 0.0 0.92 8.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.14 KPI43155.1 - 0.055 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KPI43155.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 KPI43155.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C PF13361.6 KPI43155.1 - 0.19 11.1 0.1 3.3 7.0 0.0 2.4 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain FAD_binding_4 PF01565.23 KPI43156.1 - 1.4e-22 80.0 5.7 2.1e-22 79.3 5.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI43156.1 - 2e-06 27.8 0.2 4.8e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF5583 PF17821.1 KPI43157.1 - 0.087 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5583) PfkB PF00294.24 KPI43158.1 - 9.2e-18 64.6 0.0 2.2e-17 63.3 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4129 PF13559.6 KPI43158.1 - 0.07 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Acyltransferase PF01553.21 KPI43159.1 - 1.4e-27 96.0 0.0 2.7e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KPI43159.1 - 4.8e-12 45.8 1.5 6.6e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Cytochrom_C_2 PF01322.20 KPI43159.1 - 0.028 15.3 0.8 0.091 13.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C' SRI PF08236.11 KPI43159.1 - 0.19 11.9 0.3 29 4.9 0.0 2.5 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Abhydrolase_3 PF07859.13 KPI43160.1 - 1.9e-21 76.9 0.1 2.6e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPI43160.1 - 1.6e-10 40.4 0.0 2.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KPI43160.1 - 0.069 12.0 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Translin PF01997.16 KPI43161.1 - 3.3e-49 167.6 0.0 3.9e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Translin family Syntaxin_2 PF14523.6 KPI43161.1 - 0.11 12.8 0.1 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Septin PF00735.18 KPI43162.1 - 4.9e-10 39.1 0.1 5e-09 35.8 0.1 2.1 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 KPI43162.1 - 0.00046 20.6 0.0 0.0015 18.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KPI43162.1 - 0.0076 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KPI43162.1 - 0.035 14.5 0.0 0.081 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KPI43162.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KPI43162.1 - 0.18 12.2 0.1 0.38 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPI43162.1 - 0.19 11.3 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4578 PF15147.6 KPI43164.1 - 1.4 9.8 6.7 0.36 11.7 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) Yip1 PF04893.17 KPI43165.1 - 0.006 16.3 3.5 0.006 16.3 3.5 2.9 1 1 0 2 2 2 1 Yip1 domain DUF4131 PF13567.6 KPI43165.1 - 1.5 8.4 8.4 0.24 11.0 0.4 2.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4131) FGGY_N PF00370.21 KPI43167.1 - 4.4e-67 226.2 0.0 6e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KPI43167.1 - 5.4e-57 192.7 2.3 3.5e-55 186.8 2.3 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.16 KPI43169.1 - 5.7e-32 111.0 35.0 1.5e-31 109.6 35.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KPI43169.1 - 0.00052 19.9 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RCSD PF05177.12 KPI43169.1 - 0.83 10.6 3.5 1.4 9.9 3.5 1.3 1 0 0 1 1 1 0 RCSD region Shugoshin_C PF07557.11 KPI43170.1 - 6.7e-11 41.8 3.9 6.7e-11 41.8 3.9 3.4 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.11 KPI43170.1 - 6.1e-05 22.8 4.4 0.00019 21.3 4.4 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TauD PF02668.16 KPI43171.1 - 9.2e-50 169.9 0.1 1.1e-49 169.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RL10P_insert PF17777.1 KPI43173.1 - 3e-22 78.4 0.0 8.2e-22 77.0 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KPI43173.1 - 3.4e-22 78.4 0.1 8.2e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KPI43173.1 - 2.5e-21 76.1 7.3 2.5e-21 76.1 7.3 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Chitin_synth_2 PF03142.15 KPI43174.1 - 8.1e-25 87.4 1.6 1.7e-22 79.7 2.4 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KPI43174.1 - 5.6e-14 52.5 11.5 5.6e-14 52.5 11.5 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPI43174.1 - 4.5e-12 46.3 0.0 1.1e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI43174.1 - 0.091 12.6 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 TMEM208_SND2 PF05620.11 KPI43174.1 - 0.68 9.7 5.7 0.14 12.0 1.3 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 MARVEL PF01284.23 KPI43175.1 - 6.8e-07 29.4 16.2 6.8e-07 29.4 16.2 2.1 1 1 0 2 2 2 1 Membrane-associating domain HET PF06985.11 KPI43176.1 - 1.6e-14 54.5 0.0 3.6e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Gsf2 PF11055.8 KPI43176.1 - 0.16 10.7 0.1 0.24 10.1 0.1 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 Glyco_transf_17 PF04724.13 KPI43177.1 - 3.8e-48 164.3 0.0 5.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 HET PF06985.11 KPI43178.1 - 7.1e-24 84.8 6.4 6.1e-22 78.5 0.3 2.9 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) TIP49 PF06068.13 KPI43179.1 - 2.9e-166 552.9 0.1 3.7e-166 552.6 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KPI43179.1 - 1e-22 80.0 0.1 6.2e-22 77.5 0.1 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KPI43179.1 - 1.5e-10 41.6 0.1 7.7e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPI43179.1 - 8.4e-10 38.6 0.2 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KPI43179.1 - 2.2e-06 28.0 0.1 0.051 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPI43179.1 - 9.3e-05 22.9 0.1 0.0012 19.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KPI43179.1 - 0.00095 19.5 3.1 0.031 14.6 3.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KPI43179.1 - 0.001 19.3 0.2 0.0026 18.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KPI43179.1 - 0.0013 18.5 0.1 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 KPI43179.1 - 0.0018 18.3 0.1 0.4 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KPI43179.1 - 0.0044 16.3 0.2 0.0097 15.2 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 KPI43179.1 - 0.012 15.0 0.1 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KPI43179.1 - 0.017 15.6 0.0 0.057 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KPI43179.1 - 0.023 14.0 0.2 0.07 12.5 0.0 1.9 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 KPI43179.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KPI43179.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KPI43179.1 - 0.039 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KPI43179.1 - 0.048 13.2 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PIF1 PF05970.14 KPI43179.1 - 0.049 12.8 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase IstB_IS21 PF01695.17 KPI43179.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KPI43179.1 - 0.092 12.7 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 KPI43179.1 - 0.11 11.5 0.3 0.3 10.1 0.2 1.7 1 1 1 2 2 2 0 Type II/IV secretion system protein CCDC154 PF15450.6 KPI43182.1 - 0.092 11.3 15.0 0.13 10.8 15.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 YcbB PF08664.10 KPI43182.1 - 0.21 11.6 2.8 0.47 10.5 2.8 1.6 1 0 0 1 1 1 0 YcbB domain Atg14 PF10186.9 KPI43182.1 - 0.59 9.2 9.2 1.1 8.3 9.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 KPI43182.1 - 0.71 9.3 14.9 0.13 11.7 9.7 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 KPI43182.1 - 0.71 9.2 11.4 1.2 8.4 11.4 1.3 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 KPI43182.1 - 1.8 8.0 11.0 3 7.3 11.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.11 KPI43182.1 - 6.2 6.6 9.4 1.2 8.9 4.6 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.6 KPI43182.1 - 6.7 6.0 9.4 11 5.3 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 KPI43183.1 - 7.3e-57 192.6 2.5 3.6e-51 174.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43183.1 - 6.7e-48 162.7 0.1 2.6e-37 128.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI43183.1 - 1.5e-08 34.8 0.1 3.8e-08 33.5 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI43183.1 - 0.0088 15.5 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Abhydrolase_1 PF00561.20 KPI43184.1 - 2.2e-32 112.7 0.0 9.7e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI43184.1 - 4.1e-21 75.0 0.0 8.6e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KPI43184.1 - 0.0051 16.1 0.1 2.6 7.2 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPI43184.1 - 0.053 13.0 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1202 PF06717.11 KPI43185.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) MMR_HSR1_C PF08438.10 KPI43186.1 - 3e-36 124.4 0.0 5.1e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KPI43186.1 - 1.1e-19 70.6 0.0 2.7e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI43186.1 - 4.4e-07 29.5 0.0 8.9e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KPI43186.1 - 0.011 15.8 0.4 0.048 13.7 0.2 2.1 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 KPI43186.1 - 0.014 14.9 0.3 1 8.9 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPI43186.1 - 0.018 15.0 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Ploopntkinase3 PF18751.1 KPI43186.1 - 0.022 14.7 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 KPI43186.1 - 0.043 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 KPI43186.1 - 0.044 13.9 0.2 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KPI43186.1 - 0.053 13.9 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KPI43186.1 - 0.081 13.2 0.2 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPI43186.1 - 0.099 13.2 0.0 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DAO PF01266.24 KPI43187.1 - 4.1e-36 125.3 0.1 4.9e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI43187.1 - 9.4e-07 29.0 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI43187.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI43187.1 - 0.00054 19.1 0.0 0.0014 17.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KPI43187.1 - 0.0039 17.2 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI43187.1 - 0.007 15.6 0.0 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI43187.1 - 0.027 13.7 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KPI43187.1 - 0.039 13.0 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_trans_4_2 PF13477.6 KPI43187.1 - 0.12 12.4 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Shikimate_DH PF01488.20 KPI43187.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KPI43187.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ING PF12998.7 KPI43188.1 - 7.2e-12 45.8 1.2 1.2e-10 41.9 0.6 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Vps36_ESCRT-II PF11605.8 KPI43190.1 - 0.084 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RhoGAP PF00620.27 KPI43191.1 - 8.7e-37 126.3 0.0 1.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain mRNA_decap_C PF16741.5 KPI43191.1 - 0.29 10.5 0.7 0.61 9.4 0.7 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Cytochrom_B561 PF03188.16 KPI43193.1 - 1.1e-06 28.8 6.0 2.8e-06 27.5 6.0 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KPI43193.1 - 0.017 15.3 16.4 0.018 15.2 3.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4079) XRCC4 PF06632.12 KPI43193.1 - 0.73 8.6 4.6 1.6 7.5 4.6 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 AP_endonuc_2 PF01261.24 KPI43194.1 - 6.7e-28 97.6 0.1 9.9e-28 97.0 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 KPI43194.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal CBM_5_12 PF02839.14 KPI43194.1 - 0.13 12.9 0.6 0.76 10.5 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain Ribosomal_L28 PF00830.19 KPI43195.1 - 2.8e-11 43.5 1.5 4.8e-11 42.7 1.5 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Fez1 PF06818.15 KPI43196.1 - 0.0026 18.2 19.2 0.0026 18.2 19.2 2.2 2 1 0 2 2 2 1 Fez1 TPR_MLP1_2 PF07926.12 KPI43196.1 - 0.0062 16.6 9.5 0.0062 16.6 9.5 3.2 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KPI43196.1 - 0.029 11.9 19.6 0.051 11.1 19.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BST2 PF16716.5 KPI43196.1 - 0.032 14.8 4.0 0.032 14.8 4.0 3.9 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 FPP PF05911.11 KPI43196.1 - 0.14 10.4 17.9 0.1 10.8 14.3 2.0 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 KPI43196.1 - 0.16 12.1 27.6 0.024 14.8 15.0 2.8 2 1 1 3 3 3 0 Tropomyosin like DUF2443 PF10398.9 KPI43196.1 - 0.17 11.9 0.7 0.46 10.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2443) Filament PF00038.21 KPI43196.1 - 0.31 10.6 21.5 0.18 11.3 12.7 3.1 2 1 1 3 3 3 0 Intermediate filament protein EzrA PF06160.12 KPI43196.1 - 0.4 8.8 12.3 0.18 9.9 3.3 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 KPI43196.1 - 0.44 11.0 6.6 21 5.7 0.9 3.7 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 KPI43196.1 - 0.59 9.8 27.5 0.024 14.3 19.5 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NBP1 PF08537.10 KPI43196.1 - 0.71 9.2 11.7 0.3 10.5 1.9 2.3 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 AIP3 PF03915.13 KPI43196.1 - 0.76 8.8 14.4 0.06 12.4 9.2 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 CLZ PF16526.5 KPI43196.1 - 0.79 10.1 24.9 2.5 8.5 1.0 5.1 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 KPI43196.1 - 0.83 8.9 24.8 0.95 8.8 19.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 KPI43196.1 - 1.2 9.2 10.0 0.46 10.6 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Lzipper-MIP1 PF14389.6 KPI43196.1 - 1.3 9.4 12.4 0.97 9.8 1.8 4.2 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF5082 PF16888.5 KPI43196.1 - 1.4 9.2 17.6 21 5.4 11.7 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) ADIP PF11559.8 KPI43196.1 - 1.5 8.9 31.1 0.21 11.7 7.2 3.4 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KPI43196.1 - 1.9 7.5 19.7 0.59 9.2 7.4 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KPI43196.1 - 2 8.7 14.3 1 9.6 0.6 4.0 3 1 2 5 5 4 0 Haemolysin XhlA BLOC1_2 PF10046.9 KPI43196.1 - 2 8.8 14.8 0.42 10.9 4.7 3.8 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 KPI43196.1 - 2.2 6.1 6.7 3.5 5.4 6.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 KPI43196.1 - 2.5 7.9 21.6 2.7 7.8 10.5 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 KPI43196.1 - 3.6 7.8 13.9 3.9 7.7 3.0 3.1 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KPI43196.1 - 4.2 6.2 25.4 0.83 8.5 17.9 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 KPI43196.1 - 5.1 7.1 16.0 6.9 6.7 3.9 3.0 2 1 1 3 3 2 0 Laminin Domain II TMF_DNA_bd PF12329.8 KPI43196.1 - 5.1 7.2 27.1 11 6.1 5.1 4.5 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding SKA1 PF07160.12 KPI43196.1 - 5.1 6.9 13.0 13 5.6 11.8 2.2 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 CENP-F_leu_zip PF10473.9 KPI43196.1 - 6.2 6.9 25.7 12 5.9 8.1 4.0 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 KPI43196.1 - 7 5.1 11.4 0.94 8.0 3.0 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KPI43196.1 - 7.1 6.1 17.9 35 3.8 17.4 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 KPI43196.1 - 7.8 6.6 10.7 8.5 6.5 0.5 3.1 2 1 1 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KPI43196.1 - 9.2 6.4 32.5 5.5 7.2 15.7 3.6 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 KPI43196.1 - 9.7 5.0 8.0 9 5.1 7.1 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Aldo_ket_red PF00248.21 KPI43197.1 - 1.1e-11 44.5 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MMR_HSR1 PF01926.23 KPI43200.1 - 0.00014 21.9 0.0 0.74 9.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Ribonuc_L-PSP PF01042.21 KPI43202.1 - 2.7e-25 88.7 0.0 3.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FCH PF00611.23 KPI43203.1 - 7.8e-23 80.6 2.8 9.5e-23 80.3 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KPI43203.1 - 6e-17 61.2 0.5 1.3e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KPI43203.1 - 4.2e-15 55.1 0.2 5.7e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KPI43203.1 - 3.7e-13 49.1 5.4 7.4e-13 48.2 5.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 KPI43203.1 - 0.0013 18.4 0.1 0.09 12.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 KPI43203.1 - 0.0028 17.9 0.1 0.055 13.7 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.16 KPI43203.1 - 0.0036 17.6 5.9 0.0067 16.7 5.9 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 KPI43203.1 - 0.0096 16.0 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 SH3 domain Exonuc_VII_L PF02601.15 KPI43203.1 - 0.12 12.0 6.5 3.9 7.0 3.8 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ribosomal_L36e PF01158.18 KPI43203.1 - 0.39 11.0 2.8 0.37 11.1 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L36e Tektin PF03148.14 KPI43203.1 - 1 8.1 12.0 0.088 11.5 7.1 1.6 2 0 0 2 2 2 0 Tektin family Maf1 PF09174.10 KPI43204.1 - 4.1e-60 202.9 0.0 5.9e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 KPI43204.1 - 1e-46 158.4 0.2 1.6e-46 157.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DSPc PF00782.20 KPI43205.1 - 4.1e-11 42.8 0.2 8.2e-11 41.8 0.2 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPI43205.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hemerythrin PF01814.23 KPI43206.1 - 1.4e-08 35.4 0.3 2.2e-08 34.8 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GDPD PF03009.17 KPI43207.1 - 7.5e-36 124.2 0.0 1e-35 123.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 KPI43208.1 - 6.6e-60 200.9 0.0 1.3e-59 200.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPI43208.1 - 3.9e-37 127.1 1.2 4.4e-36 123.7 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KPI43208.1 - 0.00087 19.6 0.0 0.011 16.0 0.0 2.8 1 1 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KPI43208.1 - 0.002 17.5 0.0 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KPI43208.1 - 0.0028 18.1 3.5 0.017 15.6 0.5 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_like PF09279.11 KPI43208.1 - 0.0046 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 KPI43208.1 - 0.0093 15.8 0.2 0.094 12.7 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 KPI43208.1 - 0.028 14.3 0.1 0.066 13.1 0.1 1.7 1 0 0 1 1 1 0 EF hand IFT46_B_C PF12317.8 KPI43208.1 - 0.035 13.8 0.3 0.082 12.6 0.1 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal SH3BGR PF04908.15 KPI43209.1 - 0.0027 17.8 0.0 0.0087 16.2 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein MFS_1 PF07690.16 KPI43210.1 - 2.7e-32 112.1 31.6 7.9e-32 110.5 31.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI43210.1 - 0.00064 18.7 2.1 0.00064 18.7 2.1 2.3 2 0 0 2 2 2 2 MFS_1 like family TFIIA_gamma_N PF02268.16 KPI43210.1 - 0.03 14.4 0.5 0.056 13.5 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain MBOAT_2 PF13813.6 KPI43211.1 - 1.6e-09 37.9 1.2 3.5e-09 36.8 1.2 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glu-tRNAGln PF02686.15 KPI43212.1 - 6.6e-05 23.1 0.0 0.00012 22.3 0.0 1.5 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit PRIMA1 PF16101.5 KPI43212.1 - 0.0028 17.7 0.4 0.0052 16.8 0.4 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Peptidase_C14 PF00656.22 KPI43214.1 - 7.2e-46 157.1 0.0 9.4e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PH_4 PF15404.6 KPI43215.1 - 4.8e-49 166.6 0.1 2.3e-47 161.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KPI43215.1 - 2.4e-23 81.5 0.6 7.5e-23 79.9 0.6 1.9 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KPI43215.1 - 2e-11 44.3 0.3 0.00064 20.2 0.2 5.7 3 2 0 3 3 3 3 PH domain PH_6 PF15406.6 KPI43215.1 - 0.08 13.2 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2816 PF10992.8 KPI43216.1 - 1.5 8.8 9.2 14 5.6 0.1 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2816) AbrB_C PF18277.1 KPI43217.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AbrB C-terminal domain Abhydrolase_6 PF12697.7 KPI43218.1 - 3.8e-19 70.2 7.9 6.5e-19 69.4 7.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KPI43218.1 - 0.0038 17.0 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.12 KPI43218.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KPI43218.1 - 0.023 14.0 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KPI43218.1 - 0.061 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DIOX_N PF14226.6 KPI43219.1 - 1.7e-30 106.2 0.0 2.8e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI43219.1 - 1.1e-19 70.8 0.0 1.9e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KPI43220.1 - 1.9e-51 175.0 0.0 2.9e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43220.1 - 2.7e-19 69.5 0.0 5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI43220.1 - 0.16 11.9 2.9 0.25 11.2 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KPI43220.1 - 0.2 11.2 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KPI43220.1 - 0.22 11.1 0.2 0.41 10.2 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.19 KPI43222.1 - 2.5e-41 142.0 0.0 8.5e-23 81.2 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI43222.1 - 3.2e-27 95.8 0.0 7.2e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KPI43222.1 - 8.5e-06 25.9 0.1 0.00032 20.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI43222.1 - 5.2e-05 22.5 0.0 7.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI43222.1 - 0.0083 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI43222.1 - 0.014 15.0 0.0 0.041 13.5 0.0 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPI43222.1 - 0.038 12.8 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KPI43222.1 - 0.051 12.6 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KPI43222.1 - 0.23 12.0 0.0 0.5 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 KPI43223.1 - 5.6e-24 85.2 0.0 2.3e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4238 PF14022.6 KPI43225.1 - 1.6e-41 142.7 0.0 2e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Pkinase PF00069.25 KPI43226.1 - 7.2e-67 225.5 0.0 9.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43226.1 - 7.2e-32 110.7 0.0 9.7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI43226.1 - 1e-05 24.6 0.1 1.4e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPI43226.1 - 8.6e-05 22.0 0.1 0.0003 20.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPI43226.1 - 0.00054 19.4 0.0 0.051 12.9 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KPI43226.1 - 0.00057 19.9 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KPI43226.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KPI43226.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MotA_ExbB PF01618.16 KPI43227.1 - 0.064 13.0 0.3 0.064 13.0 0.3 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Ofd1_CTDD PF10637.9 KPI43228.1 - 6.5e-79 264.9 0.0 2.6e-73 246.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KPI43228.1 - 4e-21 75.5 0.0 7.3e-20 71.4 0.0 2.7 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KPI43228.1 - 3.4e-11 43.9 0.0 8.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.13 KPI43229.1 - 3.9e-13 49.5 0.0 5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI43229.1 - 2.4e-06 27.5 0.7 4.7e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 NAD(P)H-binding Pkinase PF00069.25 KPI43230.1 - 2.4e-62 210.7 0.0 3.5e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43230.1 - 4.7e-31 108.0 0.0 2.4e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI43230.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPI43230.1 - 0.0022 17.4 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rotamase_2 PF13145.6 KPI43230.1 - 0.022 15.6 1.5 0.04 14.8 1.5 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF2486 PF10667.9 KPI43230.1 - 0.056 13.7 5.1 0.11 12.6 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) APH PF01636.23 KPI43230.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.6 2 1 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPI43230.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3944 PF13099.6 KPI43230.1 - 0.15 12.0 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) FTA2 PF13095.6 KPI43230.1 - 0.18 11.4 0.0 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SWIRM-assoc_2 PF16496.5 KPI43230.1 - 0.38 9.6 1.7 0.55 9.0 1.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RIO1 PF01163.22 KPI43230.1 - 0.48 10.0 0.0 0.48 10.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Borrelia_P83 PF05262.11 KPI43230.1 - 0.93 7.9 3.8 1.6 7.1 3.8 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein Rrn6 PF10214.9 KPI43230.1 - 1.7 7.0 6.8 2.4 6.6 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PhnG PF06754.12 KPI43230.1 - 1.8 8.5 5.7 3.2 7.7 5.7 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Filament PF00038.21 KPI43232.1 - 0.063 12.8 3.1 0.071 12.7 2.9 1.3 1 1 0 1 1 1 0 Intermediate filament protein Sugarporin_N PF11471.8 KPI43232.1 - 0.073 13.0 6.3 0.14 12.2 6.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Sulfotransfer_4 PF17784.1 KPI43233.1 - 1.1e-67 228.0 0.0 1.5e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain RIBIOP_C PF04950.12 KPI43237.1 - 7.7e-97 324.2 0.1 7.7e-97 324.2 0.1 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KPI43237.1 - 4.1e-29 100.5 0.0 1.4e-28 98.8 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KPI43237.1 - 2.4e-05 24.6 0.3 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KPI43237.1 - 3.7e-05 23.3 0.0 0.0076 15.8 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KPI43237.1 - 0.00028 21.3 0.0 0.00091 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KPI43237.1 - 0.00037 20.9 0.0 0.00097 19.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KPI43237.1 - 0.00066 19.7 0.1 0.0024 17.9 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KPI43237.1 - 0.002 18.3 0.0 0.002 18.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 KPI43237.1 - 0.0022 17.2 0.0 0.0063 15.7 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.9 KPI43237.1 - 0.0023 17.7 0.0 0.016 15.0 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KPI43237.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KPI43237.1 - 0.0069 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KPI43237.1 - 0.0082 16.7 0.0 0.0082 16.7 0.0 2.6 3 0 0 3 3 1 1 ABC transporter ATPase_2 PF01637.18 KPI43237.1 - 0.013 15.4 1.5 0.026 14.5 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KPI43237.1 - 0.017 14.7 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPI43237.1 - 0.019 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KPI43237.1 - 0.023 14.6 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 KPI43237.1 - 0.027 14.4 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KPI43237.1 - 0.031 14.8 0.1 0.031 14.8 0.1 3.5 4 0 0 4 4 3 0 AAA domain cobW PF02492.19 KPI43237.1 - 0.034 13.7 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KPI43237.1 - 0.038 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPI43237.1 - 0.039 14.2 0.2 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KPI43237.1 - 0.039 13.9 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KPI43237.1 - 0.047 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KPI43237.1 - 0.058 13.4 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KPI43237.1 - 0.064 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KPI43237.1 - 0.068 13.1 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 KPI43237.1 - 0.076 12.2 1.1 0.087 12.0 0.0 1.6 2 0 0 2 2 1 0 KAP family P-loop domain ATP_bind_1 PF03029.17 KPI43237.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KPI43237.1 - 0.14 12.4 1.5 0.18 12.0 0.0 2.0 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_11 PF13086.6 KPI43237.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.2 3 1 0 3 3 2 0 AAA domain AAA_17 PF13207.6 KPI43237.1 - 1.4 9.4 7.3 0.23 11.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain FTA4 PF13093.6 KPI43238.1 - 9.1e-42 143.2 12.1 1.5e-41 142.5 12.1 1.3 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sugar_tr PF00083.24 KPI43239.1 - 4.6e-102 342.2 21.7 5.4e-102 342.0 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43239.1 - 5.3e-26 91.4 20.0 5.3e-26 91.4 20.0 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI43239.1 - 0.00061 18.8 9.4 0.16 10.8 0.5 3.0 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.20 KPI43239.1 - 0.0014 17.0 3.6 0.0014 17.0 3.6 2.4 2 2 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family OTT_1508_deam PF14441.6 KPI43240.1 - 2e-19 69.3 1.0 4.9e-19 68.1 0.5 2.0 2 0 0 2 2 2 1 OTT_1508-like deaminase Cyclin_N PF00134.23 KPI43241.1 - 5.9e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Neur_chan_memb PF02932.16 KPI43241.1 - 7.7 6.5 6.3 33 4.4 3.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hpt PF01627.23 KPI43242.1 - 1.9e-10 40.9 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Hpt domain La PF05383.17 KPI43243.1 - 1.2e-20 73.3 0.0 2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KPI43243.1 - 7.1e-07 29.0 2.5 1.2e-06 28.3 0.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 KPI43245.1 - 1.8e-12 47.0 42.8 0.00011 22.5 2.0 6.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI43245.1 - 1.1e-11 44.6 16.6 5e-06 26.7 1.5 5.9 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPI43245.1 - 7.6e-07 29.3 0.9 0.07 13.4 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KPI43245.1 - 6.6e-06 26.5 37.3 0.0048 17.6 1.2 5.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KPI43245.1 - 0.0015 18.3 9.1 0.19 11.5 0.2 3.8 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 KPI43245.1 - 0.002 18.4 12.5 0.35 11.3 0.0 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KPI43245.1 - 0.033 14.9 1.9 0.033 14.9 1.9 2.7 2 0 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 KPI43245.1 - 0.13 12.0 0.3 0.13 12.0 0.3 5.0 6 0 0 6 6 6 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KPI43245.1 - 0.55 10.9 16.2 3.5 8.3 0.1 4.3 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-CGNR PF11706.8 KPI43245.1 - 6 6.8 12.0 20 5.2 0.1 4.2 4 0 0 4 4 4 0 CGNR zinc finger Exo_endo_phos PF03372.23 KPI43246.1 - 8.4e-12 45.1 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KPI43246.1 - 0.00079 19.5 6.4 0.0025 17.9 6.4 1.9 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KPI43246.1 - 0.058 13.2 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase SLATT_5 PF18160.1 KPI43248.1 - 0.13 11.6 6.1 0.95 8.8 0.2 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Fungal_trans PF04082.18 KPI43249.1 - 1.9e-37 128.8 0.4 4.1e-37 127.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 KPI43249.1 - 0.00083 19.8 0.0 0.00083 19.8 0.0 2.4 2 1 0 2 2 2 1 SET domain DUF4050 PF13259.6 KPI43249.1 - 0.47 10.8 5.2 1.1 9.6 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) HMG_box PF00505.19 KPI43250.1 - 8.3e-22 77.4 0.5 8.3e-22 77.4 0.5 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPI43250.1 - 7.7e-07 29.6 0.5 1.4e-06 28.8 0.5 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KPI43250.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Ccdc124 PF06244.12 KPI43250.1 - 0.034 14.7 0.1 0.034 14.7 0.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 Pkinase PF00069.25 KPI43251.1 - 2.6e-05 23.7 0.0 0.00011 21.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KPI43251.1 - 0.00014 21.3 0.1 0.01 15.2 0.0 2.8 4 0 0 4 4 4 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI43251.1 - 0.0035 17.3 0.2 0.14 12.0 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KPI43251.1 - 0.079 12.2 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 KPI43251.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 2 0 0 2 2 2 0 Fructosamine kinase RIO1 PF01163.22 KPI43251.1 - 0.21 11.2 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family TIM21 PF08294.11 KPI43252.1 - 2e-33 115.3 0.0 2.7e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KPI43252.1 - 0.00017 21.3 0.0 0.00084 19.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF5423 PF17461.2 KPI43253.1 - 0.29 9.9 9.1 0.41 9.4 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) RAP1 PF07218.11 KPI43253.1 - 0.81 7.9 10.1 0.92 7.7 10.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_capsid PF06112.11 KPI43253.1 - 6.8 6.7 21.9 10 6.2 21.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Shikimate_dh_N PF08501.11 KPI43254.1 - 3.1e-22 78.6 0.2 5.3e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KPI43254.1 - 5e-09 35.8 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KPI43254.1 - 9.7e-09 35.4 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KPI43254.1 - 0.0086 16.6 0.1 0.016 15.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KPI43254.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KPI43254.1 - 0.079 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Slu7 PF11708.8 KPI43255.1 - 6e-59 200.0 10.4 6e-59 200.0 10.4 3.0 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KPI43255.1 - 0.042 13.6 0.5 0.074 12.8 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle SUN PF03856.13 KPI43256.1 - 4e-65 219.7 10.3 1e-64 218.4 10.3 1.6 1 1 0 1 1 1 1 Beta-glucosidase (SUN family) CAP_N PF01213.19 KPI43256.1 - 0.14 11.6 5.1 0.25 10.8 5.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KPI43256.1 - 0.65 10.0 5.0 1.3 9.1 5.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MSA-2c PF12238.8 KPI43256.1 - 2.1 8.3 6.2 3.9 7.4 6.2 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c MIF4G PF02854.19 KPI43257.1 - 5.1e-57 192.9 6.3 7.3e-31 107.5 0.1 3.6 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.14 KPI43257.1 - 3e-37 128.4 9.9 1e-36 126.6 9.9 1.9 1 0 0 1 1 1 1 Up-frameshift suppressor 2 FliD_C PF07195.12 KPI43257.1 - 0.017 14.6 0.7 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Hydrolase_6 PF13344.6 KPI43259.1 - 1.2e-22 79.9 0.0 2.7e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI43259.1 - 4.7e-14 52.2 0.0 3.5e-13 49.4 0.0 2.6 3 1 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 KPI43259.1 - 0.0034 17.7 0.0 8 6.7 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase rRNA_processing PF08524.11 KPI43261.1 - 3.5 7.6 23.2 0.55 10.2 8.1 2.4 2 1 0 2 2 2 0 rRNA processing CD34_antigen PF06365.12 KPI43263.1 - 0.0016 18.1 0.1 0.0021 17.7 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.6 KPI43263.1 - 0.0063 16.8 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4190 PF13828.6 KPI43263.1 - 0.033 14.0 2.0 0.05 13.4 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Herpes_gE PF02480.16 KPI43263.1 - 0.049 12.4 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LapA_dom PF06305.11 KPI43263.1 - 0.065 13.1 2.0 0.25 11.2 1.1 2.2 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Myc_target_1 PF15179.6 KPI43263.1 - 0.097 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 TMEMspv1-c74-12 PF11044.8 KPI43263.1 - 0.23 11.5 0.0 0.56 10.2 0.0 1.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein F-box-like PF12937.7 KPI43264.1 - 2.2e-05 24.2 0.1 2.2e-05 24.2 0.1 2.4 4 0 0 4 4 4 1 F-box-like LRR_6 PF13516.6 KPI43264.1 - 0.066 13.3 3.7 4.7 7.5 0.5 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 KPI43264.1 - 0.082 13.4 1.9 1.1 9.8 0.4 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI43264.1 - 0.11 12.3 1.9 0.76 9.6 0.7 3.0 4 0 0 4 4 4 0 Leucine rich repeat F-box PF00646.33 KPI43264.1 - 0.16 11.9 3.8 0.52 10.2 2.0 2.9 3 1 0 3 3 3 0 F-box domain Sugar_tr PF00083.24 KPI43265.1 - 3.4e-60 204.2 28.1 3.5e-49 167.9 14.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 KPI43265.1 - 4.2e-18 65.3 0.4 9.8e-13 47.7 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI43265.1 - 3.5e-13 49.2 22.5 3.5e-13 49.2 22.5 3.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_L14e PF01929.17 KPI43266.1 - 1.8e-26 92.4 1.8 3.1e-26 91.7 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 PPI_Ypi1 PF07491.11 KPI43267.1 - 9.8e-24 83.0 0.2 2.2e-23 81.8 0.2 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor MRI PF15325.6 KPI43267.1 - 2.8 9.0 6.5 30 5.8 2.1 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection GCS PF03074.16 KPI43268.1 - 5e-170 565.7 0.0 6.1e-170 565.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase PIN_5 PF08745.11 KPI43268.1 - 0.2 11.0 0.0 0.46 9.9 0.0 1.5 1 0 0 1 1 1 0 PINc domain ribonuclease MFS_1 PF07690.16 KPI43269.1 - 1.1e-26 93.7 28.5 1.6e-26 93.1 28.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TatD_DNase PF01026.21 KPI43270.1 - 3.8e-35 121.5 0.0 7.5e-35 120.5 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase PH PF00169.29 KPI43271.1 - 0.00031 21.2 0.0 0.00064 20.2 0.0 1.5 1 0 0 1 1 1 1 PH domain MCM PF00493.23 KPI43272.1 - 8.5e-47 159.1 0.0 1.5e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KPI43272.1 - 1.4e-37 128.3 0.3 2.4e-37 127.6 0.3 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KPI43272.1 - 8e-33 113.9 36.4 8e-33 113.9 36.4 2.3 1 1 1 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KPI43272.1 - 1.8e-13 50.9 0.1 4.9e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KPI43272.1 - 0.0018 18.3 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF1272 PF06906.11 KPI43272.1 - 0.0083 16.2 0.6 0.016 15.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) SelR PF01641.18 KPI43272.1 - 0.08 13.0 0.1 4.8 7.3 0.1 2.3 2 0 0 2 2 2 0 SelR domain IBB PF01749.20 KPI43272.1 - 0.52 10.8 4.7 1.5 9.3 4.7 1.8 1 1 0 1 1 1 0 Importin beta binding domain CsbD PF05532.12 KPI43273.1 - 1.6e-10 40.7 16.9 5.2e-10 39.1 5.0 3.2 2 1 1 3 3 3 2 CsbD-like DUF3292 PF11696.8 KPI43273.1 - 2.8 6.2 5.8 3.1 6.0 5.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) Pmp3 PF01679.17 KPI43274.1 - 1.3e-24 86.2 8.0 1.4e-24 86.0 8.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.12 KPI43274.1 - 4.5 7.3 7.5 1.5 8.9 2.4 2.0 2 0 0 2 2 2 0 Conserved TM helix GMC_oxred_N PF00732.19 KPI43275.1 - 4.3e-58 197.0 0.0 5.7e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI43275.1 - 9e-17 61.9 0.3 7.8e-11 42.7 0.1 2.4 1 1 1 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI43275.1 - 1.1e-06 28.0 0.7 0.024 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KPI43275.1 - 0.00013 21.3 0.1 0.00048 19.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KPI43275.1 - 0.00034 20.3 2.2 0.016 14.8 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI43275.1 - 0.00037 19.7 0.1 0.00069 18.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI43275.1 - 0.0031 16.8 0.3 0.045 13.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI43275.1 - 0.0053 17.0 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI43275.1 - 0.0097 15.2 1.3 2.3 7.4 0.5 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF1996 PF09362.10 KPI43277.1 - 1.5e-87 293.5 2.1 2.3e-87 292.8 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KPI43277.1 - 1.5e-15 57.1 12.5 1.5e-15 57.1 12.5 2.0 2 0 0 2 2 2 1 WSC domain Sulfate_transp PF00916.20 KPI43278.1 - 2.7e-109 365.4 21.5 3.8e-109 364.9 21.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KPI43278.1 - 3.6e-09 36.3 0.0 7.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KPI43278.1 - 0.0023 18.3 2.6 0.0023 18.3 2.6 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 KPI43278.1 - 4.6 7.3 8.9 0.23 11.4 2.1 2.5 2 0 0 2 2 2 0 Stannin transmembrane p450 PF00067.22 KPI43279.1 - 2.5e-62 211.1 0.0 2.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MR_MLE_C PF13378.6 KPI43280.1 - 3.3e-38 131.5 0.0 5.6e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KPI43280.1 - 5.1e-15 55.7 0.0 1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HET PF06985.11 KPI43281.1 - 2.7e-17 63.5 0.0 5.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GLTP PF08718.11 KPI43282.1 - 1.9e-45 154.8 0.0 2.4e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) MFS_1 PF07690.16 KPI43283.1 - 2.9e-29 102.1 20.9 4.2e-29 101.6 20.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.6 KPI43283.1 - 6.6e-20 72.0 0.0 1.2e-19 71.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI43283.1 - 9.2e-20 71.0 0.0 2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_holin_5_2 PF16079.5 KPI43283.1 - 0.3 11.5 2.6 1.2 9.5 2.6 2.1 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V DENN PF02141.21 KPI43284.1 - 3.7e-52 177.0 0.2 7.5e-52 176.0 0.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KPI43284.1 - 4.8e-10 40.0 0.0 1.5e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KPI43284.1 - 1.7e-05 24.7 0.1 3.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 dDENN domain Bac_rhamnosid6H PF17389.2 KPI43285.1 - 3.6e-105 352.0 0.0 5.1e-105 351.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KPI43285.1 - 7.4e-41 139.8 0.0 1.3e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KPI43285.1 - 3.5e-27 94.3 0.0 9e-27 93.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KPI43285.1 - 2e-21 75.5 0.0 4.3e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF3475 PF11961.8 KPI43285.1 - 0.15 12.2 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) Thiolase_N PF00108.23 KPI43286.1 - 1.1e-61 208.5 0.1 1.7e-61 207.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI43286.1 - 2.1e-35 121.1 0.6 2.1e-35 121.1 0.6 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPI43286.1 - 0.016 14.8 4.1 0.026 14.1 2.2 2.3 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Methyltransf_34 PF11312.8 KPI43287.1 - 4.7e-101 338.1 0.0 6.1e-101 337.7 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DGF-1_C PF11040.8 KPI43289.1 - 1.3 9.1 4.5 1.2 9.2 2.5 2.1 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus G-alpha PF00503.20 KPI43290.1 - 9.4e-117 390.1 0.6 1.1e-116 389.9 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KPI43290.1 - 3.2e-15 56.0 0.8 2.2e-10 40.3 0.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KPI43290.1 - 2.1e-05 24.0 0.2 0.1 11.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KPI43290.1 - 0.0015 18.7 0.6 0.41 10.9 0.0 2.7 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KPI43290.1 - 0.081 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KPI43290.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KPI43290.1 - 0.14 11.7 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FAD_binding_3 PF01494.19 KPI43291.1 - 3.6e-14 52.8 0.2 5.4e-13 48.9 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI43291.1 - 1e-10 41.8 1.6 0.00025 20.8 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI43291.1 - 2.8e-07 30.7 0.6 7.2e-07 29.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI43291.1 - 3e-07 30.0 0.3 0.012 14.9 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI43291.1 - 0.00015 21.0 1.1 0.00019 20.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI43291.1 - 0.0006 18.6 0.4 0.0087 14.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KPI43291.1 - 0.0014 17.9 0.1 0.0033 16.7 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KPI43291.1 - 0.0023 16.9 0.1 0.24 10.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 KPI43291.1 - 0.0046 16.1 0.4 0.0065 15.6 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KPI43291.1 - 0.01 15.1 1.2 0.056 12.7 0.4 2.2 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KPI43291.1 - 0.025 13.9 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KPI43291.1 - 0.063 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KPI43291.1 - 0.068 13.7 0.0 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI43291.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KPI43291.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_S13_N PF08069.12 KPI43292.1 - 4.1e-28 97.2 0.1 6.7e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KPI43292.1 - 1.2e-14 54.3 0.1 1.7e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KPI43292.1 - 0.024 14.6 0.1 0.044 13.7 0.0 1.6 1 1 1 2 2 2 0 'Paired box' domain CENP-N PF05238.13 KPI43293.1 - 1.2e-71 242.2 0.0 1.4e-71 242.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Pro-rich PF15240.6 KPI43294.1 - 0.066 13.5 21.6 0.092 13.0 21.6 1.2 1 0 0 1 1 1 0 Proline-rich Aminotran_5 PF00266.19 KPI43295.1 - 1.2e-92 310.8 0.0 1.5e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPI43295.1 - 5.2e-07 29.2 0.0 1.6e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KPI43295.1 - 8.1e-07 28.5 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KPI43295.1 - 0.00018 20.9 0.0 0.00053 19.4 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family EF-hand_1 PF00036.32 KPI43295.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 EF hand Cys_Met_Meta_PP PF01053.20 KPI43295.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PEP_mutase PF13714.6 KPI43296.1 - 3.7e-61 206.6 0.2 4.9e-61 206.2 0.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KPI43296.1 - 2.6e-07 29.5 0.1 3.5e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Mito_fiss_reg PF05308.11 KPI43297.1 - 0.07 13.2 3.4 0.092 12.8 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KPI43297.1 - 0.085 12.3 4.4 0.11 11.9 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KPI43297.1 - 0.1 12.7 3.8 0.17 11.9 3.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1180 PF06679.12 KPI43297.1 - 0.22 12.0 3.1 0.29 11.6 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Clat_adaptor_s PF01217.20 KPI43299.1 - 3.1e-42 143.9 0.0 5e-42 143.2 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Bromodomain PF00439.25 KPI43300.1 - 3.7e-05 23.7 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 2 Bromodomain Sigma70_ner PF04546.13 KPI43300.1 - 0.03 14.2 10.7 0.21 11.4 4.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region MFS_1 PF07690.16 KPI43301.1 - 4.3e-27 95.0 25.5 6.8e-26 91.0 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI43301.1 - 8.5e-11 41.4 4.4 8.5e-11 41.4 4.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 KPI43302.1 - 1.3e-19 70.3 2.7 1.3e-19 70.3 2.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43302.1 - 5e-06 26.5 11.9 7.3e-06 26.0 10.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FolB PF02152.18 KPI43302.1 - 0.042 14.4 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroneopterin aldolase MAP65_ASE1 PF03999.12 KPI43302.1 - 1.1 7.9 3.5 2 7.0 2.6 1.8 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) bZIP_2 PF07716.15 KPI43303.1 - 5e-13 48.9 14.0 8.3e-13 48.2 14.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KPI43303.1 - 1.4e-05 25.1 9.8 2.4e-05 24.3 9.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor FPP PF05911.11 KPI43303.1 - 0.0031 15.8 6.0 0.004 15.4 6.0 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ZapB PF06005.12 KPI43303.1 - 0.044 14.2 8.6 0.08 13.4 8.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF4164 PF13747.6 KPI43303.1 - 0.3 11.4 9.2 0.055 13.7 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) SlyX PF04102.12 KPI43303.1 - 0.63 10.7 3.6 1.5 9.5 3.4 1.7 1 1 0 1 1 1 0 SlyX UPF0242 PF06785.11 KPI43303.1 - 1.4 9.0 9.3 2 8.5 9.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 KPI43303.1 - 2.1 8.9 14.6 0.26 11.8 8.3 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Seryl_tRNA_N PF02403.22 KPI43303.1 - 6.5 7.0 13.4 3.4 8.0 7.7 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain VasI PF11319.8 KPI43304.1 - 0.1 12.3 0.4 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 YkpC PF17447.2 KPI43304.1 - 0.11 13.3 1.6 0.11 13.3 1.6 2.6 3 0 0 3 3 3 0 Uncharacterized YkpC-like PTS_IIA PF02255.16 KPI43304.1 - 0.22 11.6 2.3 0.2 11.7 0.5 1.8 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Mak16 PF04874.14 KPI43304.1 - 0.49 11.0 10.3 0.96 10.1 10.3 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region BUD22 PF09073.10 KPI43304.1 - 5.6 6.2 14.5 6.7 5.9 14.5 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KPI43304.1 - 6.4 4.7 18.3 9 4.3 18.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ANTH PF07651.16 KPI43305.1 - 4.7e-77 258.7 0.0 4.7e-77 258.7 0.0 3.3 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KPI43305.1 - 3.8e-55 186.3 6.5 3.8e-55 186.3 6.5 5.9 3 2 1 6 6 6 2 I/LWEQ domain TcdB_N PF12918.7 KPI43305.1 - 0.73 10.2 7.4 0.091 13.1 1.4 2.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Sec62 PF03839.16 KPI43306.1 - 1.3e-65 221.0 1.4 1.3e-65 221.0 1.4 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 tRNA-synt_1g PF09334.11 KPI43306.1 - 0.12 11.1 2.0 0.17 10.6 2.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) MAT1 PF06391.13 KPI43306.1 - 0.31 10.8 15.8 0.14 11.9 11.4 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DFRP_C PF16543.5 KPI43306.1 - 0.88 10.1 8.4 0.35 11.4 1.9 2.6 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 ANAPC1 PF12859.7 KPI43306.1 - 6.2 7.4 6.5 1.8 9.1 3.3 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Dicty_REP PF05086.12 KPI43306.1 - 7.3 4.4 6.3 12 3.8 6.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AA_permease_2 PF13520.6 KPI43307.1 - 9.7e-60 202.6 49.5 1.2e-59 202.3 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI43307.1 - 6.4e-26 91.0 38.9 8.9e-26 90.5 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease SGL PF08450.12 KPI43308.1 - 1e-20 74.4 0.0 5.5e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KPI43308.1 - 0.0057 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Arylesterase QH-AmDH_gamma PF08992.11 KPI43308.1 - 0.022 14.8 0.0 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit NHL PF01436.21 KPI43308.1 - 0.046 13.8 0.2 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 NHL repeat Str_synth PF03088.16 KPI43308.1 - 0.051 13.7 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Strictosidine synthase DNA_binding_1 PF01035.20 KPI43309.1 - 6.2e-20 71.1 0.4 1e-19 70.4 0.0 1.6 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PHO4 PF01384.20 KPI43310.1 - 1.2e-56 192.2 6.1 1.3e-56 192.1 6.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family Kinocilin PF15033.6 KPI43310.1 - 0.24 11.1 0.1 0.24 11.1 0.1 3.3 2 1 1 3 3 3 0 Kinocilin protein Phasin_2 PF09361.10 KPI43312.1 - 0.25 11.6 5.8 1.1 9.6 5.8 2.0 1 1 0 1 1 1 0 Phasin protein F-box-like_2 PF13013.6 KPI43313.1 - 0.035 14.1 0.2 4.1 7.4 0.1 2.4 2 0 0 2 2 2 0 F-box-like domain STE2 PF02116.15 KPI43314.1 - 2.3e-12 46.8 6.2 2.3e-12 46.8 6.2 2.3 2 1 0 2 2 2 2 Fungal pheromone mating factor STE2 GPCR Bac_export_2 PF01312.19 KPI43314.1 - 2.1 7.5 7.7 2.6 7.2 7.3 1.3 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Fungal_trans_2 PF11951.8 KPI43315.1 - 5.3e-25 88.0 4.6 4.2e-13 48.9 0.5 2.8 2 1 0 3 3 3 2 Fungal specific transcription factor domain Acyl_transf_3 PF01757.22 KPI43315.1 - 3.9e-18 65.6 30.3 7.9e-18 64.6 30.3 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF4293 PF14126.6 KPI43315.1 - 8.2 6.7 10.4 0.7 10.1 1.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Aminotran_5 PF00266.19 KPI43316.1 - 1.9e-21 76.5 0.0 4.6e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KPI43316.1 - 8.3e-06 25.2 0.0 1.6e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 KPI43316.1 - 0.048 12.3 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 KPI43316.1 - 0.061 11.9 0.0 0.75 8.3 0.0 2.0 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPI43316.1 - 0.085 12.2 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_8 PF01501.20 KPI43317.1 - 1.7e-12 47.5 0.0 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 Dynactin PF12455.8 KPI43318.1 - 2.4e-70 237.0 10.6 2.4e-70 237.0 10.6 5.3 4 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 KPI43318.1 - 5.9e-22 77.5 0.3 1.1e-21 76.6 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KPI43318.1 - 0.0047 16.3 17.5 0.0047 16.3 17.5 5.4 2 2 2 5 5 5 1 Uncharacterized coiled-coil protein (DUF2353) Trans_reg_C PF00486.28 KPI43318.1 - 0.062 13.4 2.9 0.3 11.2 0.2 3.5 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal TSC22 PF01166.18 KPI43318.1 - 0.41 11.0 0.1 0.41 11.0 0.1 6.7 6 1 1 7 7 7 0 TSC-22/dip/bun family IMS PF00817.20 KPI43319.1 - 2.1e-34 118.7 0.0 3.3e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KPI43319.1 - 7.9e-12 45.9 0.0 1.6e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KPI43319.1 - 9.6e-10 37.9 0.0 3.5e-09 36.1 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF3602 PF12223.8 KPI43320.1 - 2.4e-10 40.9 11.9 1.9e-09 38.0 3.6 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3602) NMT1_3 PF16868.5 KPI43320.1 - 0.018 14.5 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 NMT1-like family LURAP PF14854.6 KPI43320.1 - 0.045 13.7 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 Leucine rich adaptor protein CAF-1_p60_C PF15512.6 KPI43320.1 - 1.3 9.5 4.7 0.75 10.3 0.3 2.0 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal SVIP PF15811.5 KPI43320.1 - 2.9 8.4 7.7 0.79 10.2 0.7 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein SUI1 PF01253.22 KPI43321.1 - 4.3e-27 94.4 3.6 8.3e-27 93.5 3.6 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.8 KPI43321.1 - 1.1e-09 38.4 2.2 3.1e-09 37.0 2.2 1.7 1 0 0 1 1 1 1 N-glycosylation protein DUF4131 PF13567.6 KPI43321.1 - 0.0036 17.0 0.1 0.01 15.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DNA_pol_B PF00136.21 KPI43322.1 - 7.4e-89 298.5 0.0 4.2e-88 296.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KPI43322.1 - 2.1e-19 69.8 0.0 1.9e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KPI43322.1 - 2.9e-17 62.9 4.3 6.4e-17 61.8 4.3 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta AMP-binding PF00501.28 KPI43323.1 - 3.7e-55 187.2 0.0 1.4e-54 185.3 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI43323.1 - 6.1e-06 27.1 0.0 1.2e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 KPI43324.1 - 1.8e-63 215.0 19.8 3.2e-60 204.3 15.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI43324.1 - 4.3e-22 78.5 28.8 4.3e-22 78.5 28.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TPK_catalytic PF04263.16 KPI43325.1 - 1.5e-30 105.7 0.0 2e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KPI43325.1 - 2.3e-18 65.7 0.0 3.6e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Gly-zipper_YMGG PF13441.6 KPI43326.1 - 0.031 14.0 8.3 0.047 13.4 8.3 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 KPI43326.1 - 0.046 13.6 13.0 0.07 13.0 13.0 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain AC_N PF16214.5 KPI43326.1 - 1 8.4 3.7 1.6 7.8 3.7 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Gly-zipper_Omp PF13488.6 KPI43326.1 - 1.3 9.1 14.1 3.8 7.6 14.1 1.7 1 1 1 2 2 2 0 Glycine zipper Tcp11 PF05794.13 KPI43328.1 - 9.9e-72 242.4 4.5 9.9e-72 242.4 4.5 2.1 2 0 0 2 2 2 1 T-complex protein 11 IQ PF00612.27 KPI43328.1 - 0.089 12.6 1.5 0.36 10.8 1.5 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF676 PF05057.14 KPI43329.1 - 7.3e-49 166.2 0.0 1.1e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KPI43329.1 - 3.3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KPI43329.1 - 8.7e-05 23.2 0.8 0.00062 20.4 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KPI43329.1 - 0.0065 15.8 0.0 0.035 13.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KPI43329.1 - 0.0084 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KPI43329.1 - 0.053 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Herpes_DNAp_acc PF04929.12 KPI43330.1 - 0.33 9.9 14.2 0.2 10.6 8.7 2.0 1 1 1 2 2 2 0 Herpes DNA replication accessory factor ADH_zinc_N PF00107.26 KPI43331.1 - 1.9e-24 86.1 0.3 3.9e-24 85.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI43331.1 - 1.6e-05 24.7 0.0 4.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI43331.1 - 4.7e-05 24.5 0.0 0.00011 23.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI43331.1 - 0.00037 20.0 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short PF00106.25 KPI43331.1 - 0.016 14.6 0.3 0.029 13.8 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.6 KPI43331.1 - 0.42 11.1 1.5 3 8.3 1.5 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Homeodomain PF00046.29 KPI43332.1 - 3.3e-13 49.3 1.1 7.9e-13 48.0 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KPI43332.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain UPF0139 PF03669.13 KPI43333.1 - 2.2e-05 24.2 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Glyco_transf_34 PF05637.12 KPI43334.1 - 4.5e-53 180.4 0.0 1e-52 179.3 0.0 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_S8e PF01201.22 KPI43335.1 - 2.2e-53 180.1 2.3 2.5e-53 179.9 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Shikimate_dh_N PF08501.11 KPI43336.1 - 1e-18 67.3 0.0 2.3e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KPI43336.1 - 5.2e-05 23.3 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KPI43337.1 - 4.3e-40 137.7 0.0 6.2e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43337.1 - 1.7e-38 132.0 0.0 2.1e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KPI43337.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KPI43337.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KPI43337.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) F-box-like PF12937.7 KPI43338.1 - 0.00046 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 KPI43340.1 - 1.7e-36 126.1 28.7 6.3e-22 78.1 8.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI43340.1 - 4.6e-25 88.3 37.6 1.8e-12 46.9 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Prog_receptor PF02161.15 KPI43342.1 - 0.14 10.9 0.4 0.16 10.7 0.4 1.0 1 0 0 1 1 1 0 Progesterone receptor MT0933_antitox PF14013.6 KPI43342.1 - 1.7 9.0 8.6 1 9.7 2.6 2.4 1 1 1 2 2 2 0 MT0933-like antitoxin protein Anp1 PF03452.14 KPI43344.1 - 3e-104 348.1 0.0 3.6e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KPI43344.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Tubulin_C PF03953.17 KPI43346.1 - 9.8e-33 113.0 0.1 1.2e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain COX14 PF14880.6 KPI43347.1 - 3.8e-13 49.1 0.3 3.8e-13 49.1 0.3 2.1 3 0 0 3 3 3 1 Cytochrome oxidase c assembly PIEZO PF15917.5 KPI43347.1 - 0.21 11.1 4.3 0.3 10.5 4.3 1.2 1 0 0 1 1 1 0 Piezo F-box-like PF12937.7 KPI43348.1 - 9.3e-06 25.4 0.1 2.2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI43348.1 - 0.0078 16.1 0.8 0.019 14.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain ERO1 PF04137.15 KPI43349.1 - 5.1e-126 420.6 2.2 5.1e-126 420.6 2.2 1.8 1 1 1 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNase_NucA_NucB PF14040.6 KPI43350.1 - 0.00036 20.9 0.0 0.0015 18.8 0.0 2.1 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB Sel1 PF08238.12 KPI43352.1 - 3.5e-10 40.2 7.3 0.00058 20.4 0.2 3.7 3 0 0 3 3 3 3 Sel1 repeat SPX PF03105.19 KPI43353.1 - 6e-21 75.8 4.2 3.5e-12 46.9 0.0 2.7 2 1 1 3 3 3 2 SPX domain Trimer_CC PF08954.11 KPI43353.1 - 0.059 12.9 0.8 0.19 11.3 0.8 1.8 1 0 0 1 1 1 0 Trimerisation motif Val_tRNA-synt_C PF10458.9 KPI43353.1 - 0.24 11.7 2.6 0.27 11.5 0.5 2.1 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm AA_permease_2 PF13520.6 KPI43354.1 - 1.1e-47 162.9 58.0 1.7e-45 155.6 58.0 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI43354.1 - 7.6e-11 41.3 53.1 1.1e-08 34.2 24.8 2.1 1 1 1 2 2 2 2 Amino acid permease DUF4210 PF13915.6 KPI43355.1 - 4.8e-28 97.5 0.2 9.9e-28 96.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KPI43355.1 - 8.5e-24 83.5 0.6 2.5e-23 82.0 0.1 2.1 2 0 0 2 2 2 1 Chromosome segregation during meiosis ADK PF00406.22 KPI43356.1 - 5e-35 120.8 0.0 5.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KPI43356.1 - 4e-15 56.4 0.1 5.5e-11 43.0 0.0 2.7 2 1 1 3 3 3 2 AAA domain ADK_lid PF05191.14 KPI43356.1 - 4.5e-14 52.1 0.1 1.1e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KPI43356.1 - 0.0012 19.4 0.0 0.0041 17.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPI43356.1 - 0.0039 17.4 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KPI43356.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3328 PF11807.8 KPI43357.1 - 1.2e-24 87.3 3.9 1.6e-24 86.9 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Thioredoxin_15 PF18403.1 KPI43357.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1664 PF07889.12 KPI43358.1 - 0.00022 21.3 0.1 0.00062 19.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CSN5_C PF18323.1 KPI43358.1 - 0.014 16.3 3.9 2.3 9.2 0.8 3.1 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Spc7 PF08317.11 KPI43358.1 - 0.039 12.8 0.7 0.087 11.7 0.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KPI43358.1 - 0.041 14.4 0.0 0.19 12.3 0.0 2.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TPR_12 PF13424.6 KPI43358.1 - 0.052 13.9 14.4 5.6 7.3 2.4 4.5 3 2 0 3 3 3 0 Tetratricopeptide repeat Atg14 PF10186.9 KPI43358.1 - 0.086 11.9 4.6 0.17 11.0 4.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 KPI43358.1 - 0.095 13.0 1.9 3.6 7.9 0.4 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein ANAPC3 PF12895.7 KPI43358.1 - 0.13 12.5 2.7 30 4.9 0.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KPI43358.1 - 0.17 12.4 11.8 0.26 11.8 0.2 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Fmp27_WPPW PF10359.9 KPI43358.1 - 0.18 10.6 4.9 0.34 9.7 4.9 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DinB_2 PF12867.7 KPI43358.1 - 0.27 11.7 6.5 0.31 11.5 1.0 2.9 2 1 0 2 2 2 0 DinB superfamily Striatin PF08232.12 KPI43358.1 - 3.3 8.3 7.4 11 6.6 7.4 2.0 1 1 0 1 1 1 0 Striatin family PfkB PF00294.24 KPI43359.1 - 2.2e-07 30.5 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1478 PF07349.11 KPI43359.1 - 0.067 13.1 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) Phosphorylase PF00343.20 KPI43360.1 - 0 1059.1 0.0 0 1058.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA_35 PF14516.6 KPI43360.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain TPR_1 PF00515.28 KPI43361.1 - 1.3e-13 50.2 1.2 8.6e-06 25.4 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KPI43361.1 - 2.5e-13 49.0 1.2 0.00024 21.0 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KPI43361.1 - 1.9e-07 30.8 0.2 0.0018 18.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPI43361.1 - 2.5e-07 30.9 0.1 0.0018 18.6 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KPI43361.1 - 1.9e-06 28.2 0.0 2.5 8.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPI43361.1 - 1e-05 25.2 0.1 0.0008 19.3 0.1 3.0 1 1 0 1 1 1 1 Tetratricopeptide repeat PB1 PF00564.24 KPI43361.1 - 1.9e-05 24.5 0.1 3.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.6 KPI43361.1 - 2e-05 24.2 0.6 0.00065 19.3 0.1 3.4 1 1 1 2 2 2 1 TPR repeat TPR_16 PF13432.6 KPI43361.1 - 0.0024 18.5 0.1 0.12 13.0 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KPI43361.1 - 0.0078 16.5 0.5 0.32 11.5 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KPI43361.1 - 0.056 13.6 0.0 0.75 10.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI43361.1 - 0.15 13.0 0.1 1.8 9.6 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Lyase_1 PF00206.20 KPI43362.1 - 8.1e-36 124.0 1.5 2.4e-29 102.7 0.1 2.5 1 1 1 2 2 2 2 Lyase ADSL_C PF10397.9 KPI43362.1 - 3.9e-21 75.4 0.4 3.2e-20 72.4 0.0 2.7 4 0 0 4 4 4 1 Adenylosuccinate lyase C-terminus BRCT PF00533.26 KPI43363.1 - 0.00086 19.6 0.0 0.021 15.2 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TLV_coat PF00429.19 KPI43363.1 - 0.066 11.9 0.2 0.095 11.4 0.2 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) V-SNARE PF05008.15 KPI43364.1 - 4.5 7.7 8.2 0.44 11.0 1.0 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus RNA_polI_A14 PF08203.11 KPI43364.1 - 9.5 7.0 10.3 79 4.1 0.2 4.4 4 0 0 4 4 4 0 Yeast RNA polymerase I subunit RPA14 Lectin_C PF00059.21 KPI43365.1 - 0.0041 17.8 0.3 2.6 8.8 0.1 2.5 2 0 0 2 2 2 2 Lectin C-type domain Glyco_hydro_10 PF00331.20 KPI43367.1 - 8.2e-102 340.6 0.0 9.8e-102 340.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DSBA PF01323.20 KPI43368.1 - 1.5e-16 60.7 0.1 2e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Amidase PF01425.21 KPI43369.1 - 3.7e-37 128.4 1.4 6.9e-37 127.5 1.0 1.5 2 0 0 2 2 2 1 Amidase GST_N PF02798.20 KPI43370.1 - 2.9e-12 46.7 0.1 6.4e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI43370.1 - 1e-11 44.9 0.0 9.2e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI43370.1 - 1.3e-11 44.7 0.0 2.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI43370.1 - 4e-10 39.8 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI43370.1 - 2.2e-09 37.4 0.0 6.4e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI43370.1 - 9e-09 35.2 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BSP PF04450.12 KPI43371.1 - 8.9e-59 198.8 0.7 4.8e-57 193.1 0.7 2.6 1 1 0 1 1 1 1 Peptidase of plants and bacteria Mucin PF01456.17 KPI43371.1 - 1.6e-07 31.4 14.4 1.6e-07 31.4 14.4 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 KPI43371.1 - 0.084 10.9 8.8 0.12 10.5 8.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4512 PF14975.6 KPI43371.1 - 0.28 12.0 2.1 0.61 10.9 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) MGC-24 PF05283.11 KPI43371.1 - 0.58 10.6 11.6 1 9.8 11.6 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin OCD_Mu_crystall PF02423.15 KPI43372.1 - 3.5e-11 42.6 0.0 0.00021 20.4 0.0 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KPI43372.1 - 5.8e-07 29.6 0.0 0.00021 21.4 0.0 2.7 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF3954 PF13128.6 KPI43374.1 - 0.085 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) adh_short PF00106.25 KPI43375.1 - 4.3e-37 127.5 0.6 6.1e-37 127.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43375.1 - 2.3e-25 89.5 0.3 3.3e-25 89.0 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KPI43375.1 - 9.2e-06 25.2 0.0 1.5e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 KPI43375.1 - 0.0042 17.3 0.1 0.0072 16.6 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI43375.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 KPI43375.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Peptidase_S24 PF00717.23 KPI43376.1 - 5.3e-08 32.7 0.4 1.7e-07 31.1 0.4 1.9 1 1 0 1 1 1 1 Peptidase S24-like DUF2785 PF10978.8 KPI43376.1 - 0.06 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Peptidase_S26 PF10502.9 KPI43376.1 - 0.15 11.9 0.0 7.9 6.3 0.0 2.7 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 VIT PF08487.10 KPI43377.1 - 1.5e-32 112.1 0.1 3.1e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KPI43377.1 - 1.9e-28 99.4 0.0 4.4e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KPI43377.1 - 1.6e-14 53.5 0.1 3.4e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KPI43377.1 - 6e-09 36.4 0.0 1.9e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KPI43377.1 - 2.5e-07 31.3 0.0 6.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Nucleoporin_FG PF13634.6 KPI43377.1 - 0.0016 19.3 25.6 0.0036 18.1 11.3 3.2 2 1 1 3 3 3 2 Nucleoporin FG repeat region Nab1 PF04902.12 KPI43377.1 - 0.13 12.7 0.4 0.27 11.6 0.4 1.4 1 0 0 1 1 1 0 Conserved region in Nab1 AMP-binding PF00501.28 KPI43378.1 - 2.8e-73 246.9 0.1 3.6e-73 246.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI43378.1 - 8e-13 49.2 0.5 2.8e-12 47.4 0.4 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RCC_reductase PF06405.11 KPI43379.1 - 0.042 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) DUF3760 PF12586.8 KPI43381.1 - 0.0038 17.4 0.1 0.51 10.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3760) BA14K PF07886.11 KPI43382.1 - 2.3 8.2 17.6 4.2 7.3 1.4 4.7 3 0 0 3 3 3 0 BA14K-like protein Peptidase_S64 PF08192.11 KPI43382.1 - 9.4 4.6 10.3 12 4.2 10.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Amdase PF17645.1 KPI43383.1 - 2.4e-06 27.3 0.0 2.9e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 KPI43383.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase NmrA PF05368.13 KPI43384.1 - 1.8e-07 31.0 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI43384.1 - 6.6e-07 29.4 0.2 6.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 KPI43384.1 - 0.085 13.1 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KPI43384.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KPI43385.1 - 8.1e-16 58.2 0.4 8e-13 48.3 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain Uds1 PF15456.6 KPI43386.1 - 7.1e-41 139.4 1.6 7.1e-41 139.4 1.6 5.4 2 1 3 5 5 5 2 Up-regulated During Septation GAS PF13851.6 KPI43386.1 - 0.0027 17.1 8.9 0.0027 17.1 8.9 6.1 4 1 1 6 6 6 2 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 KPI43386.1 - 4.5 5.1 49.5 0.24 9.3 0.1 3.9 2 1 1 4 4 4 0 V-type ATPase 116kDa subunit family PGAP1 PF07819.13 KPI43387.1 - 2.1e-86 289.4 0.0 3e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KPI43387.1 - 3.1e-05 24.7 0.0 7.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KPI43387.1 - 0.00089 19.2 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KPI43387.1 - 0.0029 17.3 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI43387.1 - 0.0063 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KPI43387.1 - 0.0091 15.5 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KPI43387.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 KPI43387.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KPI43387.1 - 0.21 10.4 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF2828 PF11443.8 KPI43388.1 - 0.05 11.7 0.2 0.071 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NICE-3 PF07406.11 KPI43389.1 - 0.00058 19.9 0.0 0.00058 19.9 0.0 2.0 3 0 0 3 3 3 1 NICE-3 protein DUF4129 PF13559.6 KPI43389.1 - 0.0033 17.7 0.1 0.0075 16.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Ribosomal_L16 PF00252.18 KPI43390.1 - 3.9e-31 107.8 0.1 6.5e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 3Beta_HSD PF01073.19 KPI43391.1 - 1.8e-09 37.0 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPI43391.1 - 2e-09 37.3 0.1 5.2e-09 35.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI43391.1 - 5.7e-08 32.2 0.0 4.8e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KPI43391.1 - 1.1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI43391.1 - 3.4e-06 26.8 0.2 7.1e-06 25.7 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KPI43391.1 - 0.00029 20.4 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KH_1 PF00013.29 KPI43392.1 - 6.6e-36 122.0 0.9 3.9e-07 29.8 0.0 7.3 7 0 0 7 7 7 6 KH domain SUV3_C PF12513.8 KPI43392.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Pkinase PF00069.25 KPI43394.1 - 9.7e-43 146.4 0.0 2.1e-42 145.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43394.1 - 3.1e-15 56.2 0.0 4.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI43394.1 - 7.8e-07 29.3 0.6 0.0038 17.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family KIX_2 PF16987.5 KPI43394.1 - 0.00023 21.1 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 KIX domain Kdo PF06293.14 KPI43394.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPI43394.1 - 0.0036 16.7 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPI43394.1 - 0.0066 15.3 0.0 0.0098 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KPI43394.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SF1-HH PF16275.5 KPI43395.1 - 5.7e-44 149.1 0.7 5.7e-44 149.1 0.7 1.8 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KPI43395.1 - 7e-09 35.4 4.7 1.2e-05 25.1 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KPI43395.1 - 0.0052 16.6 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.6 KPI43395.1 - 0.013 15.3 0.5 0.013 15.3 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 KPI43395.1 - 0.04 13.9 0.4 0.49 10.4 0.0 2.5 1 1 1 2 2 2 0 Zinc knuckle eIF3g PF12353.8 KPI43395.1 - 0.12 12.7 2.5 2.4 8.6 0.2 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.6 KPI43395.1 - 4.6 7.2 6.8 0.35 10.8 0.5 2.4 3 0 0 3 3 3 0 Zinc knuckle Macro PF01661.21 KPI43396.1 - 4e-41 139.8 0.3 6.3e-41 139.1 0.3 1.3 1 0 0 1 1 1 1 Macro domain RAMP PF04901.13 KPI43397.1 - 0.067 13.2 4.8 0.34 10.9 0.4 2.9 3 0 0 3 3 3 0 Receptor activity modifying family RTA1 PF04479.13 KPI43398.1 - 1.1e-63 214.5 1.4 1.1e-63 214.5 1.4 1.3 2 0 0 2 2 2 1 RTA1 like protein Ribosomal_L7Ae PF01248.26 KPI43399.1 - 1.6e-19 69.4 4.3 1.1e-18 66.7 0.7 3.1 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KPI43399.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 MPM1 PF17234.2 KPI43399.1 - 0.2 11.9 5.3 0.41 10.9 5.3 1.6 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 AAA PF00004.29 KPI43401.1 - 7.7e-18 65.2 0.0 1.7e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KPI43401.1 - 0.03 14.6 0.1 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KPI43401.1 - 0.075 13.4 0.0 4.2 7.7 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KPI43401.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KPI43402.1 - 1.3e-61 208.3 0.0 2.6e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI43402.1 - 3.8e-22 78.7 0.1 6.1e-21 74.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI43402.1 - 1.6e-08 34.8 0.2 5.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Use1 PF09753.9 KPI43403.1 - 2e-07 31.0 12.0 2.8e-07 30.5 11.7 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 FAM75 PF14650.6 KPI43403.1 - 0.011 15.4 0.5 0.011 15.4 0.5 1.9 2 0 0 2 2 2 0 FAM75 family DUF2738 PF10927.8 KPI43403.1 - 0.066 12.3 1.0 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Endomucin PF07010.12 KPI43403.1 - 0.18 11.7 8.3 0.3 11.0 8.3 1.3 1 0 0 1 1 1 0 Endomucin HECT PF00632.25 KPI43404.1 - 2.8e-70 237.2 0.0 4e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ADH_N PF08240.12 KPI43405.1 - 7.7e-26 90.1 2.1 2e-25 88.8 2.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI43405.1 - 1.1e-20 73.9 0.3 2.7e-20 72.7 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI43405.1 - 0.00034 20.9 0.1 0.00069 19.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KPI43405.1 - 0.00045 19.8 0.1 0.0018 17.8 0.1 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPI43405.1 - 0.00063 19.1 1.4 0.0011 18.2 1.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KPI43405.1 - 0.0014 19.7 0.0 0.0033 18.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KPI43405.1 - 0.05 13.2 0.3 0.091 12.3 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KPI43405.1 - 0.076 13.5 0.2 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 KPI43405.1 - 0.12 11.7 1.4 1.4 8.2 0.9 2.2 2 0 0 2 2 2 0 ThiF family Pep_deformylase PF01327.21 KPI43405.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Polypeptide deformylase 2-Hacid_dh_C PF02826.19 KPI43405.1 - 0.17 11.2 0.3 0.27 10.6 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PQ-loop PF04193.14 KPI43406.1 - 1.6e-20 72.6 4.6 3.1e-20 71.7 0.8 2.5 2 0 0 2 2 2 1 PQ loop repeat Acyl_transf_3 PF01757.22 KPI43406.1 - 0.022 13.8 4.7 0.024 13.7 4.7 1.2 1 0 0 1 1 1 0 Acyltransferase family Zip PF02535.22 KPI43407.1 - 7.2e-55 186.5 1.1 1.1e-54 185.9 1.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Tetraspanin PF00335.20 KPI43408.1 - 0.0099 15.6 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family GPHR_N PF12537.8 KPI43408.1 - 0.03 14.4 2.2 0.034 14.2 0.3 2.2 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal CclA_1 PF16942.5 KPI43408.1 - 0.048 13.9 3.0 0.25 11.6 0.7 2.1 2 0 0 2 2 2 0 Putative cyclic bacteriocin DUF4574 PF15141.6 KPI43408.1 - 0.053 13.4 0.2 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CAAD PF14159.6 KPI43408.1 - 0.27 11.1 1.7 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PIG-F PF06699.11 KPI43409.1 - 2.6e-50 171.1 5.5 3.5e-50 170.7 5.5 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4396 PF14342.6 KPI43409.1 - 0.019 15.3 2.7 0.036 14.4 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) HypD PF01924.16 KPI43410.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Aa_trans PF01490.18 KPI43411.1 - 1e-80 271.5 25.7 1.2e-80 271.2 25.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mito_carr PF00153.27 KPI43412.1 - 4.7e-55 183.5 0.4 1.1e-17 63.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KPI43412.1 - 0.029 13.6 0.8 6.8 5.7 0.1 3.2 3 1 0 3 3 3 0 Gammaproteobacterial serine protease SH3_9 PF14604.6 KPI43413.1 - 9.8e-11 41.4 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI43413.1 - 3.5e-07 29.7 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KPI43413.1 - 4.3e-07 29.5 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 KPI43413.1 - 0.00043 20.4 2.7 0.00077 19.6 2.7 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 KPI43413.1 - 0.025 13.4 1.6 0.033 13.1 1.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Herpes_gE PF02480.16 KPI43413.1 - 0.11 11.3 0.3 0.23 10.2 0.3 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF533 PF04391.12 KPI43413.1 - 0.99 9.0 4.3 15 5.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Gram_pos_anchor PF00746.21 KPI43413.1 - 4.3 7.4 9.0 0.91 9.5 0.4 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif FAM70 PF14967.6 KPI43413.1 - 6.1 6.2 7.3 14 5.1 7.3 1.5 1 0 0 1 1 1 0 FAM70 protein DUF2613 PF11021.8 KPI43413.1 - 6.9 6.9 9.0 7.7 6.7 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) dsrm PF00035.26 KPI43414.1 - 4.8e-07 30.4 0.0 1.3e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KPI43414.1 - 9.8e-06 25.8 0.0 0.0021 18.2 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KPI43414.1 - 0.012 16.2 0.0 0.084 13.5 0.0 2.4 2 1 0 2 2 2 0 Ribonuclease III domain Ribul_P_3_epim PF00834.19 KPI43415.1 - 3.7e-50 170.1 0.0 2.2e-48 164.3 0.0 2.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KPI43415.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 KPI43415.1 - 0.03 13.6 0.2 0.05 12.9 0.2 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KPI43415.1 - 0.05 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Phosphodiest PF01663.22 KPI43415.1 - 0.054 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Macoilin PF09726.9 KPI43418.1 - 3.6 6.0 13.7 4.7 5.6 13.7 1.2 1 0 0 1 1 1 0 Macoilin family AMP-binding PF00501.28 KPI43419.1 - 1.2e-86 291.0 0.0 1.4e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI43419.1 - 6e-14 52.8 0.0 2.3e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AIRC PF00731.20 KPI43419.1 - 0.11 12.1 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 AIR carboxylase NDT80_PhoG PF05224.12 KPI43420.1 - 3.3e-36 125.2 0.0 6.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Nucleos_tra2_N PF01773.20 KPI43421.1 - 0.0047 17.5 0.1 0.018 15.6 0.1 1.9 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus RGS PF00615.19 KPI43421.1 - 0.029 14.7 0.0 0.11 12.8 0.0 2.0 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF3491 PF11996.8 KPI43422.1 - 0.22 9.3 0.0 0.31 8.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) Aldedh PF00171.22 KPI43425.1 - 8.9e-156 519.0 0.0 1.1e-155 518.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NCD1 PF04904.13 KPI43425.1 - 0.082 12.9 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Cullin PF00888.22 KPI43426.1 - 4.2e-191 636.7 12.6 5.6e-191 636.3 12.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KPI43426.1 - 8.8e-27 92.9 2.1 4.6e-26 90.6 2.1 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain SatD PF16264.5 KPI43426.1 - 0.026 14.1 0.4 0.21 11.2 0.0 2.4 2 1 1 3 3 3 0 SatD family (SatD) PCI PF01399.27 KPI43426.1 - 0.088 13.3 0.8 1 9.9 0.2 2.9 2 0 0 2 2 2 0 PCI domain WSC PF01822.19 KPI43427.1 - 4.8e-78 257.4 85.5 4.8e-16 58.7 11.9 5.6 5 0 0 5 5 5 5 WSC domain PQQ_3 PF13570.6 KPI43427.1 - 3.1e-05 24.3 5.1 0.077 13.5 0.3 4.1 3 0 0 3 3 3 2 PQQ-like domain ASH PF15780.5 KPI43427.1 - 0.19 12.0 1.9 25 5.2 0.0 3.3 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PQQ PF01011.21 KPI43427.1 - 8.6 6.5 10.1 35 4.6 0.1 4.5 4 0 0 4 4 4 0 PQQ enzyme repeat Transp_cyt_pur PF02133.15 KPI43428.1 - 2.4e-101 339.7 44.9 2.8e-101 339.5 44.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PKcGMP_CC PF16808.5 KPI43429.1 - 1.1e-05 25.2 3.9 1.9e-05 24.4 3.9 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF737 PF05300.11 KPI43429.1 - 0.11 12.9 0.5 0.15 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Kinesin_assoc PF16183.5 KPI43429.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinesin-associated DnaJ_C PF01556.18 KPI43430.1 - 1.8e-38 131.9 0.2 2.4e-38 131.5 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPI43430.1 - 3.1e-25 88.1 1.2 4.9e-25 87.4 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPI43430.1 - 6.7e-16 58.4 18.9 1.2e-15 57.6 18.9 1.4 1 0 0 1 1 1 1 DnaJ central domain zf_Rg PF17915.1 KPI43430.1 - 0.076 12.4 7.5 0.14 11.5 0.5 3.3 3 0 0 3 3 3 0 Reverse gyrase zinc finger HypA PF01155.19 KPI43430.1 - 0.078 13.0 10.5 1.4 9.0 2.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KPI43430.1 - 1.3 9.1 16.4 3.4 7.7 2.8 2.4 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KPI43430.1 - 3.1 7.8 9.3 3.9 7.5 2.8 2.3 1 1 2 3 3 3 0 zinc-ribbons TRAF6_Z2 PF18048.1 KPI43430.1 - 5.7 7.1 6.9 10 6.3 0.1 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 CRM1_C PF08767.11 KPI43431.1 - 1.1e-136 455.2 8.2 2.2e-136 454.2 4.5 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KPI43431.1 - 1.8e-39 135.2 9.9 9.7e-39 132.8 7.8 3.4 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KPI43431.1 - 1.5e-33 114.3 4.1 3.8e-33 112.9 3.3 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KPI43431.1 - 4.3e-30 103.6 2.6 7.3e-30 102.8 1.1 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KPI43431.1 - 2e-19 68.8 3.3 5.5e-19 67.4 3.3 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KPI43431.1 - 7.7e-10 38.6 0.0 3.6e-09 36.4 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KPI43431.1 - 0.0062 16.5 2.9 0.23 11.4 0.0 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KPI43431.1 - 0.073 12.3 0.1 0.16 11.1 0.1 1.5 1 0 0 1 1 1 0 Hemocyanin, copper containing domain MIP PF00230.20 KPI43432.1 - 3.2e-43 148.0 5.4 4.3e-43 147.6 5.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Acetyltransf_8 PF13523.6 KPI43433.1 - 2.7e-48 163.4 0.0 3.9e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPI43433.1 - 0.0022 18.7 0.0 0.0052 17.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain UQ_con PF00179.26 KPI43433.1 - 1.5 8.5 3.6 3.9 7.1 3.6 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme MFS_1 PF07690.16 KPI43434.1 - 1.2e-26 93.5 10.9 1.5e-26 93.1 10.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5492 PF17596.2 KPI43434.1 - 0.14 12.5 0.3 0.39 11.1 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5492) DUF3267 PF11667.8 KPI43434.1 - 0.98 9.7 6.3 0.85 9.9 3.6 2.2 2 0 0 2 2 2 0 Putative zincin peptidase CorA PF01544.18 KPI43435.1 - 1.1e-09 38.1 1.4 4.1e-09 36.2 1.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AMPKBI PF04739.15 KPI43435.1 - 0.091 13.0 0.2 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain TBK1_CCD1 PF18394.1 KPI43435.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 DUF1736 PF08409.11 KPI43435.1 - 0.3 11.1 1.0 0.66 10.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) RelB_N PF18506.1 KPI43436.1 - 2 8.3 4.2 17 5.3 0.4 2.2 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain Cnd2 PF05786.14 KPI43437.1 - 0.079 11.6 1.4 0.1 11.3 1.4 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 MEDS PF14417.6 KPI43437.1 - 0.097 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain NmrA PF05368.13 KPI43438.1 - 1.7e-18 67.0 0.0 2.5e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI43438.1 - 2.5e-12 47.1 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI43438.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KPI43438.1 - 0.048 13.7 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KPI43438.1 - 0.07 13.3 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KPI43438.1 - 0.087 13.3 0.0 0.24 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding HIM1 PF08732.10 KPI43438.1 - 0.093 12.2 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 HIM1 3HCDH_N PF02737.18 KPI43438.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mus7 PF09462.10 KPI43441.1 - 2e-24 86.4 6.7 5.6e-24 85.0 6.7 1.7 1 1 0 1 1 1 1 Mus7/MMS22 family Ribonuclease_3 PF00636.26 KPI43442.1 - 1.5e-33 115.6 0.0 1.2e-18 67.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KPI43442.1 - 7.4e-25 87.6 3.8 6.1e-13 49.0 0.0 4.0 3 1 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KPI43442.1 - 1.2e-19 70.2 1.8 1.6e-18 66.7 0.1 3.2 3 0 0 3 3 3 1 Dicer dimerisation domain DEAD PF00270.29 KPI43442.1 - 9e-17 61.4 0.0 2.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI43442.1 - 1.5e-13 51.0 0.0 1e-12 48.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI43442.1 - 7.3e-12 45.6 0.0 2.3e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KPI43442.1 - 0.035 14.4 0.1 0.78 10.0 0.0 3.1 2 1 1 3 3 3 0 AAA domain RRM_1 PF00076.22 KPI43443.1 - 1.8e-24 85.3 0.0 6.3e-15 54.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.20 KPI43443.1 - 1.6e-23 83.7 0.1 7.1e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI43443.1 - 4e-17 62.2 0.0 9.1e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein RRM_7 PF16367.5 KPI43443.1 - 0.005 16.9 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif DUF1797 PF08796.10 KPI43443.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) Pyr_redox_3 PF13738.6 KPI43444.1 - 2.9e-11 43.2 0.0 1.1e-07 31.4 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI43444.1 - 1.5e-09 36.9 0.1 5.2e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI43444.1 - 4.5e-07 29.4 0.0 0.00054 19.3 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI43444.1 - 1.3e-05 25.3 0.0 0.0003 21.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF4440 PF14534.6 KPI43444.1 - 0.0012 19.2 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) 2-Hacid_dh_C PF02826.19 KPI43444.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPI43444.1 - 0.0024 16.6 0.2 0.081 11.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KPI43444.1 - 0.003 16.9 0.0 0.006 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPI43444.1 - 0.043 12.9 0.3 0.07 12.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain SnoaL_2 PF12680.7 KPI43444.1 - 0.081 13.6 0.2 0.29 11.8 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain TrkA_N PF02254.18 KPI43444.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RhoGAP PF00620.27 KPI43447.1 - 8.2e-48 162.1 0.2 2.9e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KPI43447.1 - 1.3e-14 54.2 17.2 1.9e-09 37.6 1.7 2.4 2 0 0 2 2 2 2 LIM domain bZIP_1 PF00170.21 KPI43447.1 - 6.6 6.9 6.7 2 8.5 0.4 3.1 3 0 0 3 3 3 0 bZIP transcription factor zf-FLZ PF04570.14 KPI43447.1 - 8.9 5.9 10.7 8.3 6.0 8.0 2.3 1 1 1 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Aldedh PF00171.22 KPI43448.1 - 2.1e-99 333.1 9.2 8.9e-56 189.3 0.8 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family KH_7 PF17214.3 KPI43448.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 KH domain DUF4267 PF14087.6 KPI43449.1 - 0.081 13.0 7.5 0.18 11.9 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Transp_cyt_pur PF02133.15 KPI43450.1 - 5.1e-35 121.1 32.8 4.3e-34 118.0 32.8 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MRAP PF15183.6 KPI43450.1 - 0.69 9.9 0.0 0.69 9.9 0.0 3.1 3 1 2 5 5 5 0 Melanocortin-2 receptor accessory protein family OST3_OST6 PF04756.13 KPI43450.1 - 5.2 6.3 6.1 0.41 9.9 0.9 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family MFS_5 PF05631.14 KPI43451.1 - 6.2e-61 206.3 9.3 9.3e-61 205.7 9.3 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KPI43451.1 - 1.6e-15 56.9 30.7 1.6e-15 56.9 30.7 1.9 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF1664 PF07889.12 KPI43451.1 - 0.5 10.4 1.3 1.1 9.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_hydro_32N PF00251.20 KPI43453.1 - 5.3e-26 91.9 6.8 6.4e-26 91.6 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain zf-UBR PF02207.20 KPI43454.1 - 1.4e-13 50.8 4.6 1.4e-13 50.8 4.6 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) NYAP_C PF15452.6 KPI43454.1 - 0.047 13.5 0.1 0.047 13.5 0.1 2.2 3 0 0 3 3 3 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Pyr_redox_2 PF07992.14 KPI43455.1 - 5.5e-10 39.0 0.0 4.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI43455.1 - 1.2e-06 28.0 0.0 1.4e-05 24.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI43455.1 - 1.4e-06 27.1 0.0 1e-05 24.2 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KPI43455.1 - 1.9e-05 24.0 0.0 0.00069 18.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KPI43455.1 - 8.9e-05 22.6 0.4 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KPI43455.1 - 0.13 11.3 0.2 0.22 10.5 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KPI43455.1 - 0.14 12.4 0.7 0.37 11.1 0.1 2.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Mt_ATP-synt_B PF05405.14 KPI43456.1 - 3.2e-49 166.7 1.9 4e-49 166.4 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) BON PF04972.17 KPI43456.1 - 1.3 9.3 5.3 8.2 6.8 0.1 3.9 3 1 1 4 4 4 0 BON domain Band_7 PF01145.25 KPI43457.1 - 3.7e-23 82.5 7.4 7.5e-23 81.4 7.4 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KPI43457.1 - 0.00061 19.0 4.0 0.00082 18.5 4.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Steroid_dh PF02544.16 KPI43458.1 - 1.3e-32 112.8 0.1 2.1e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KPI43458.1 - 6.4e-06 25.9 0.9 8.1e-06 25.5 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KPI43458.1 - 0.0019 18.5 0.5 0.0046 17.3 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase SH3_18 PF18354.1 KPI43459.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 CarS bacterial SH3 domain ADH_zinc_N PF00107.26 KPI43460.1 - 7.8e-11 42.1 0.0 2.7e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI43460.1 - 7.2e-06 25.9 0.2 0.00016 21.5 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Phosphodiest PF01663.22 KPI43461.1 - 1.6e-89 301.0 0.7 2.1e-89 300.6 0.7 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KPI43461.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.23 KPI43461.1 - 0.096 12.1 0.1 11 5.3 0.0 2.4 1 1 1 2 2 2 0 Sulfatase Arf PF00025.21 KPI43462.1 - 1.5e-74 249.2 0.1 1.7e-74 249.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KPI43462.1 - 4.5e-14 52.7 0.0 6.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KPI43462.1 - 7.9e-12 45.1 0.0 9e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KPI43462.1 - 2.7e-11 43.2 1.6 3.2e-07 29.8 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KPI43462.1 - 2.9e-11 43.2 0.0 3.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KPI43462.1 - 1.9e-10 40.5 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPI43462.1 - 0.00027 21.0 0.0 0.00051 20.1 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KPI43462.1 - 0.027 13.8 0.3 0.048 13.0 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase PTPA PF03095.15 KPI43463.1 - 1.3e-109 366.3 0.0 1.5e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein F-box-like PF12937.7 KPI43464.1 - 0.00039 20.2 0.0 0.0083 16.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KPI43464.1 - 0.002 18.0 0.0 0.0081 16.0 0.0 2.0 2 0 0 2 2 2 1 F-box F-box PF00646.33 KPI43464.1 - 0.037 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain SSF PF00474.17 KPI43465.1 - 6.1e-21 74.8 29.1 9e-21 74.2 29.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family FPN1 PF06963.12 KPI43466.1 - 7.9e-106 354.2 18.2 9.1e-106 354.0 18.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Methyltransf_24 PF13578.6 KPI43467.1 - 1.3e-06 29.4 0.1 3.1e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI43467.1 - 0.0038 17.9 0.0 0.0089 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI43467.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KPI43467.1 - 0.094 13.5 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_3 PF00933.21 KPI43468.1 - 3.9e-70 236.8 0.0 5.5e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KPI43468.1 - 4.4e-07 30.1 0.0 7.6e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 KPI43468.1 - 0.001 19.3 0.0 0.074 13.2 0.0 3.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI43468.1 - 0.0029 17.5 0.0 0.0083 16.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI43468.1 - 0.06 13.8 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2014 PF09427.10 KPI43469.1 - 3.2e-80 269.3 0.2 4.8e-80 268.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KPI43469.1 - 8.8e-19 67.2 0.6 1.9e-18 66.1 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KPI43469.1 - 0.0014 18.7 2.2 0.0023 18.0 0.3 2.0 2 0 0 2 2 2 1 bZIP transcription factor ZapB PF06005.12 KPI43469.1 - 0.014 15.8 0.5 0.066 13.7 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB TadZ_N PF16968.5 KPI43469.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Nnf1 PF03980.14 KPI43469.1 - 0.27 11.6 2.1 0.64 10.4 2.1 1.7 1 1 0 1 1 1 0 Nnf1 Pentapeptide PF00805.22 KPI43470.1 - 0.0045 16.6 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KPI43470.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) TPR_2 PF07719.17 KPI43471.1 - 0.0002 21.2 1.7 0.017 15.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPI43471.1 - 0.00025 21.3 2.8 0.13 12.5 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPI43471.1 - 0.0015 18.6 0.0 0.0048 17.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPI43471.1 - 0.0015 19.1 3.0 3.4 8.4 2.6 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KPI43471.1 - 0.0044 17.7 6.2 0.009 16.8 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPI43471.1 - 0.0047 16.7 0.0 0.028 14.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KPI43471.1 - 0.0049 16.7 1.8 0.063 13.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KPI43471.1 - 0.0073 16.8 0.4 0.47 11.0 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KPI43471.1 - 0.01 15.5 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 KPI43471.1 - 0.032 14.3 1.4 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.10 KPI43471.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_9 PF13371.6 KPI43471.1 - 0.065 13.4 1.6 7.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI43471.1 - 0.19 12.4 7.5 0.27 12.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI43471.1 - 0.24 12.1 3.8 0.84 10.4 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat MCM PF00493.23 KPI43472.1 - 5.7e-33 113.9 0.0 1e-32 113.0 0.0 1.4 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 KPI43472.1 - 2.7e-24 85.4 1.6 2.9e-24 85.3 0.1 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KPI43472.1 - 0.049 13.0 0.1 0.15 11.4 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI UEV PF05743.13 KPI43473.1 - 8.5e-30 103.1 0.0 1.7e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KPI43473.1 - 3.1e-14 52.7 0.0 9.6e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain HAUS-augmin3 PF14932.6 KPI43473.1 - 0.0021 17.7 6.4 0.0031 17.2 6.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 TMF_TATA_bd PF12325.8 KPI43473.1 - 0.033 14.4 2.1 0.051 13.8 2.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 KPI43473.1 - 0.035 13.2 2.2 0.063 12.4 2.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 KPI43473.1 - 0.064 12.5 4.7 0.099 11.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KPI43473.1 - 0.13 11.1 1.1 0.19 10.6 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KPI43473.1 - 0.17 11.9 7.9 0.27 11.3 7.9 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 KPI43473.1 - 0.19 12.4 0.4 0.35 11.5 0.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF5082 PF16888.5 KPI43473.1 - 0.29 11.4 4.8 0.56 10.5 4.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KPI43473.1 - 0.31 11.5 2.9 0.52 10.9 2.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0565 PF10561.9 KPI43473.1 - 0.33 10.1 0.2 0.46 9.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Prominin PF05478.11 KPI43473.1 - 0.41 8.5 1.8 0.56 8.1 1.8 1.1 1 0 0 1 1 1 0 Prominin Filament PF00038.21 KPI43473.1 - 0.77 9.3 2.8 1.1 8.7 2.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 KPI43473.1 - 1.7 8.5 4.2 16 5.4 4.2 2.1 1 1 0 1 1 1 0 Septum formation initiator Arg_decarbox_C PF17944.1 KPI43474.1 - 0.15 12.6 0.1 3.1 8.4 0.0 2.8 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension DUF4482 PF14818.6 KPI43477.1 - 0.0028 18.5 1.1 0.0028 18.5 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4482) XkdW PF09636.10 KPI43477.1 - 0.058 13.5 0.5 0.62 10.2 0.1 2.4 2 0 0 2 2 2 0 XkdW protein DUF2205 PF10224.9 KPI43477.1 - 0.15 12.1 1.3 0.42 10.6 1.3 1.7 1 0 0 1 1 1 0 Short coiled-coil protein SlyX PF04102.12 KPI43477.1 - 0.37 11.4 6.3 13 6.5 0.1 2.9 2 0 0 2 2 2 0 SlyX Nop25 PF09805.9 KPI43478.1 - 0.0013 19.2 2.4 0.0013 19.2 2.4 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) MMtag PF10159.9 KPI43478.1 - 0.4 11.0 4.6 0.65 10.3 3.8 1.8 1 1 0 1 1 1 0 Multiple myeloma tumor-associated AMP-binding PF00501.28 KPI43479.1 - 3.9e-29 101.5 0.0 6.3e-27 94.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme PA26 PF04636.13 KPI43479.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_M20 PF01546.28 KPI43480.1 - 7.6e-30 104.2 0.7 1.1e-29 103.6 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI43480.1 - 1.6e-07 31.2 0.0 3.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPI43480.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF2236 PF09995.9 KPI43482.1 - 2e-32 113.2 0.4 2.9e-32 112.7 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) SET PF00856.28 KPI43483.1 - 0.0011 19.3 0.0 0.01 16.2 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KPI43483.1 - 0.023 14.8 2.1 0.023 14.8 2.1 2.2 2 0 0 2 2 2 0 MYND finger Goodbye PF17109.5 KPI43484.1 - 1.1e-21 77.5 0.2 4.7e-21 75.5 0.2 2.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 KPI43484.1 - 1.5e-05 25.3 0.0 0.00032 21.0 0.0 2.8 1 1 1 2 2 2 1 AAA domain TPR_1 PF00515.28 KPI43484.1 - 9.8e-05 22.0 1.0 0.56 10.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KPI43484.1 - 0.0001 22.8 0.0 0.00094 19.6 0.0 2.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.6 KPI43484.1 - 0.00025 21.6 2.6 14 6.8 0.1 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KPI43484.1 - 0.00028 21.1 2.3 0.52 10.6 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KPI43484.1 - 0.0003 20.6 4.5 3.5 7.6 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KPI43484.1 - 0.0014 18.5 3.4 0.041 13.9 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KPI43484.1 - 0.0049 16.9 7.7 11 6.4 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KPI43484.1 - 0.031 14.9 0.3 1.7 9.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI43484.1 - 0.78 10.5 4.3 19 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box PF00646.33 KPI43485.1 - 0.0021 17.9 0.1 0.0043 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain HhH-GPD PF00730.25 KPI43486.1 - 6.9e-05 23.3 0.0 0.0001 22.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KPI43486.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Whi5 PF08528.11 KPI43488.1 - 2.4e-10 39.8 0.2 4.7e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Whi5 like adh_short_C2 PF13561.6 KPI43489.1 - 0.0083 15.7 0.0 0.0088 15.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43489.1 - 0.22 11.0 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NTF2 PF02136.20 KPI43490.1 - 2.8e-25 89.2 0.2 4.2e-25 88.7 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KPI43490.1 - 2.4e-08 33.7 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KPI43490.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KPI43490.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET PF00856.28 KPI43492.1 - 6.5e-13 49.4 0.0 8.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 SET domain Inhibitor_I9 PF05922.16 KPI43492.1 - 0.029 15.0 0.0 0.071 13.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 EHN PF06441.12 KPI43493.1 - 2e-37 127.8 2.1 5.4e-37 126.5 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI43493.1 - 2e-09 37.5 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Avl9 PF09794.9 KPI43494.1 - 1.4e-108 363.0 0.0 8.5e-107 357.1 0.0 2.1 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KPI43494.1 - 5.3e-08 32.8 0.1 0.0012 18.8 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KPI43494.1 - 0.00083 19.0 0.2 0.21 11.1 0.4 2.8 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 KPI43494.1 - 0.04 13.9 0.8 0.12 12.4 0.5 1.8 2 0 0 2 2 2 0 DENN (AEX-3) domain Bac_luciferase PF00296.20 KPI43495.1 - 0.016 14.7 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Flavodoxin_3 PF12641.7 KPI43495.1 - 0.22 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain FR47 PF08445.10 KPI43496.1 - 4.1e-09 36.3 0.0 1.8e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 KPI43496.1 - 0.00033 21.3 0.0 0.0011 19.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI43496.1 - 0.006 16.8 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI43496.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TMEM51 PF15345.6 KPI43497.1 - 2.6 7.8 5.9 0.27 11.1 1.2 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 SNARE_assoc PF09335.11 KPI43498.1 - 3.2e-16 59.9 6.6 9.6e-16 58.4 3.1 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2207 PF09972.9 KPI43498.1 - 0.25 10.1 0.9 0.49 9.1 0.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DSPn PF14671.6 KPI43499.1 - 1.3e-41 142.3 0.0 2.4e-39 135.0 0.0 2.4 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KPI43499.1 - 1.7e-17 63.5 0.4 3.3e-17 62.5 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KPI43499.1 - 3.6e-05 23.4 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KPI43499.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate PAN_4 PF14295.6 KPI43501.1 - 3.1e-21 75.0 24.5 8.8e-07 28.7 1.1 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 KPI43501.1 - 1.4e-14 53.8 10.0 0.0019 18.1 0.1 4.3 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 KPI43501.1 - 3.1e-13 49.3 23.2 0.0025 17.6 1.1 4.4 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.11 KPI43501.1 - 0.075 13.2 23.4 1.7 8.8 0.8 4.5 4 0 0 4 4 4 0 PAN-like domain HSP70 PF00012.20 KPI43502.1 - 1.9e-164 548.2 5.1 1.9e-164 548.2 5.1 2.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KPI43502.1 - 2.2e-10 39.9 0.0 1.5e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 KPI43502.1 - 0.092 12.8 0.2 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain FtsA PF14450.6 KPI43502.1 - 1.4 9.4 8.0 7 7.1 0.0 3.2 3 2 0 3 3 3 0 Cell division protein FtsA PEHE PF15275.6 KPI43502.1 - 1.4 9.5 4.6 3.8 8.2 4.6 1.7 1 0 0 1 1 1 0 PEHE domain AAA_23 PF13476.6 KPI43502.1 - 5 7.6 10.3 19 5.7 10.3 2.0 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KPI43503.1 - 4.9e-67 225.2 0.2 6.7e-67 224.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KPI43503.1 - 3e-31 107.7 0.0 1.6e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KPI43503.1 - 1.2e-17 63.7 0.0 3e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KPI43503.1 - 4.3e-12 45.9 0.0 9.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KPI43503.1 - 4.4e-12 46.2 0.1 1.7e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPI43503.1 - 0.00022 21.3 0.1 0.00048 20.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PLA2_B PF01735.18 KPI43504.1 - 1.6e-26 92.8 0.0 6.3e-26 90.8 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Aminotran_1_2 PF00155.21 KPI43507.1 - 2.1e-83 280.5 0.0 5.7e-83 279.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Fungal_trans_2 PF11951.8 KPI43509.1 - 1.6e-05 23.9 1.7 1.9e-05 23.6 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_1 PF00133.22 KPI43510.1 - 7.4e-33 113.7 0.0 8.7e-24 83.7 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KPI43510.1 - 5.2e-16 58.4 0.1 1.4e-09 37.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KPI43510.1 - 7.3e-10 39.0 2.0 8e-10 38.9 0.7 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KPI43510.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Herpes_UL49_5 PF05702.11 KPI43510.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein p450 PF00067.22 KPI43511.1 - 4.9e-44 150.8 0.0 6.9e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 EPL1 PF10513.9 KPI43512.1 - 3.9e-29 102.1 0.0 1e-28 100.7 0.0 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.6 KPI43512.1 - 3e-14 52.3 1.9 5.6e-14 51.4 1.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KPI43512.1 - 2.7e-10 40.0 5.7 5.5e-10 39.0 5.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KPI43512.1 - 0.0038 17.4 0.8 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-PHD-like PF15446.6 KPI43512.1 - 0.0052 16.4 0.7 0.011 15.3 0.7 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 KPI43512.1 - 0.076 13.2 1.4 0.13 12.5 0.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 KPI43512.1 - 0.086 12.8 4.3 0.18 11.7 4.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KPI43512.1 - 0.35 10.8 5.0 0.049 13.5 0.6 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RanBP PF00641.18 KPI43512.1 - 3.2 7.1 4.5 6 6.3 1.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF5327 PF17261.2 KPI43512.1 - 9.8 7.0 7.6 15 6.4 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5327) DUF3176 PF11374.8 KPI43513.1 - 9e-25 87.0 0.7 9e-25 87.0 0.7 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3176) DUF4134 PF13572.6 KPI43513.1 - 0.041 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) URO-D PF01208.17 KPI43515.1 - 1.1e-97 327.3 0.0 1.3e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) LRR_4 PF12799.7 KPI43516.1 - 0.74 10.3 10.1 16 6.1 0.2 4.9 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Acyltransferase PF01553.21 KPI43517.1 - 5.3e-11 42.3 0.0 8.5e-10 38.4 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KPI43518.1 - 3e-55 187.4 0.0 4.6e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43518.1 - 8.4e-31 107.2 0.0 2.5e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI43518.1 - 0.002 17.1 0.1 0.0044 16.0 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KPI43518.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BRCT PF00533.26 KPI43519.1 - 5.3e-14 52.4 0.0 1.4e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KPI43519.1 - 1.2e-09 38.7 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KPI43519.1 - 3.9e-08 33.4 0.0 7.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KPI43519.1 - 0.00098 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPI43519.1 - 0.0037 17.4 1.5 0.0047 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KPI43519.1 - 0.0053 17.2 0.9 0.041 14.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KPI43519.1 - 0.012 15.9 0.0 0.042 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI43519.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KPI43519.1 - 0.069 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KPI43519.1 - 0.075 13.6 0.1 0.075 13.6 0.1 2.2 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KPI43519.1 - 0.18 11.7 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Hepatitis_core PF00906.20 KPI43520.1 - 0.96 9.0 5.9 1.7 8.2 5.9 1.3 1 0 0 1 1 1 0 Hepatitis core antigen UCR_hinge PF02320.16 KPI43521.1 - 2.5e-12 46.8 4.3 5.6e-12 45.7 4.3 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein BUD22 PF09073.10 KPI43521.1 - 0.12 11.6 31.3 0.15 11.3 31.3 1.0 1 0 0 1 1 1 0 BUD22 DUF3399 PF11879.8 KPI43521.1 - 0.22 11.9 7.8 0.37 11.1 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3399) DUF1754 PF08555.10 KPI43522.1 - 1.5e-09 38.5 21.0 1.3e-08 35.5 21.0 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) ALMT PF11744.8 KPI43522.1 - 8.2 5.1 9.3 9.2 5.0 9.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 KPI43522.1 - 10 4.7 7.0 12 4.5 7.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Na_sulph_symp PF00939.19 KPI43523.1 - 1.4e-24 87.0 32.7 2.6e-24 86.1 32.7 1.3 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KPI43523.1 - 1.5e-22 80.1 40.3 2.3e-21 76.3 36.5 2.5 2 1 1 3 3 3 2 Citrate transporter SPX PF03105.19 KPI43523.1 - 2.6e-15 57.3 2.8 3.9e-15 56.7 2.8 1.2 1 0 0 1 1 1 1 SPX domain Asp-B-Hydro_N PF05279.11 KPI43524.1 - 4.2 7.4 9.3 5.1 7.1 9.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sugar_tr PF00083.24 KPI43525.1 - 3.9e-19 68.9 13.7 3e-18 65.9 12.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43525.1 - 5.6e-14 51.8 28.7 1.7e-11 43.7 7.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily HECT PF00632.25 KPI43526.1 - 1.3e-73 248.1 0.0 1.9e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FSAP_sig_propep PF03032.15 KPI43526.1 - 0.28 11.2 1.3 0.64 10.1 1.3 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide GFA PF04828.14 KPI43528.1 - 3.1e-08 33.9 0.5 2.6e-05 24.5 0.5 2.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KPI43528.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.11 KPI43528.1 - 0.73 9.5 8.5 0.15 11.8 0.7 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HD PF01966.22 KPI43529.1 - 2e-08 34.5 0.1 2.8e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 KPI43529.1 - 0.0097 15.5 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD_4 PF13328.6 KPI43529.1 - 0.015 15.0 0.4 0.025 14.3 0.4 1.5 1 1 0 1 1 1 0 HD domain HDOD PF08668.12 KPI43529.1 - 0.062 12.8 0.0 0.35 10.3 0.0 2.0 1 1 0 1 1 1 0 HDOD domain DASH_Dad2 PF08654.10 KPI43530.1 - 2.2e-29 101.8 0.2 2.9e-29 101.4 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 KPI43530.1 - 0.0095 16.1 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RICTOR_N PF14664.6 KPI43530.1 - 0.025 13.6 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term GRA6 PF05084.13 KPI43531.1 - 0.048 13.6 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) LPG_synthase_TM PF03706.13 KPI43531.1 - 0.066 12.7 0.4 0.28 10.6 0.2 2.0 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region EpuA PF11772.8 KPI43532.1 - 1.2 8.9 3.9 1.8 8.3 3.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta GMC_oxred_N PF00732.19 KPI43533.1 - 1.5e-46 159.1 0.0 2.4e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI43533.1 - 8.8e-32 110.6 0.1 2.4e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 KPI43533.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1771 PF08590.10 KPI43534.1 - 1.1e-23 83.3 6.2 1.1e-23 83.3 6.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KPI43534.1 - 7.4e-11 42.3 0.3 2.4e-10 40.6 0.3 1.9 1 0 0 1 1 1 1 Smr domain Peptidase_M14 PF00246.24 KPI43535.1 - 3.7e-12 46.7 0.1 1.2e-11 45.0 0.1 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KPI43535.1 - 2.4e-05 23.6 0.3 0.00028 20.1 0.1 2.2 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 KPI43535.1 - 0.032 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) AAA PF00004.29 KPI43536.1 - 5.7e-15 55.9 0.0 7.1e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KPI43536.1 - 0.00035 20.3 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KPI43536.1 - 0.0038 17.2 0.1 0.024 14.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 KPI43536.1 - 0.0057 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain BCS1_N PF08740.11 KPI43536.1 - 0.0094 15.9 3.3 0.0094 15.9 3.3 3.1 3 2 0 3 3 2 1 BCS1 N terminal AAA_18 PF13238.6 KPI43536.1 - 0.021 15.4 0.3 0.27 11.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KPI43536.1 - 0.023 15.1 0.1 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KPI43536.1 - 0.031 14.7 2.2 0.1 13.0 0.0 2.8 2 1 1 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 KPI43536.1 - 0.06 13.6 0.1 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KPI43536.1 - 0.064 13.8 4.0 3.8 8.0 1.3 4.3 4 2 0 4 4 4 0 ABC transporter SRA PF18491.1 KPI43536.1 - 0.26 11.4 3.3 6.8 6.8 0.0 3.4 3 0 0 3 3 3 0 SET and RING associated domain Tubulin PF00091.25 KPI43537.1 - 2.2e-68 230.4 0.0 2.6e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 KPI43537.1 - 1.7e-07 31.5 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KPI43537.1 - 0.0048 16.1 0.0 0.0062 15.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KPI43537.1 - 0.034 13.8 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Ribosomal_L1 PF00687.21 KPI43538.1 - 2.3e-59 200.6 3.3 3.3e-59 200.1 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.25 KPI43539.1 - 1.1e-16 61.0 0.0 6e-10 38.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43539.1 - 0.00095 18.5 0.0 0.041 13.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase PAPA-1 PF04795.12 KPI43541.1 - 1.8e-20 73.5 3.8 1.8e-20 73.5 3.8 2.7 3 0 0 3 3 3 1 PAPA-1-like conserved region SDA1 PF05285.12 KPI43541.1 - 0.0028 17.2 17.6 0.0043 16.5 17.6 1.3 1 0 0 1 1 1 1 SDA1 DNA_pol_phi PF04931.13 KPI43541.1 - 0.94 7.5 23.2 0.23 9.5 5.5 2.2 2 0 0 2 2 2 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KPI43541.1 - 4.3 7.8 35.3 1.8 9.0 9.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mcp5_PH PF12814.7 KPI43542.1 - 0.048 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Dpy-30 PF05186.13 KPI43543.1 - 8.7e-05 22.1 0.0 0.00035 20.2 0.0 1.9 1 1 0 1 1 1 1 Dpy-30 motif DUF334 PF03904.13 KPI43544.1 - 0.86 9.1 4.7 0.13 11.8 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) CAP_N PF01213.19 KPI43545.1 - 4.7e-99 331.9 13.4 6.8e-99 331.3 10.3 2.3 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KPI43545.1 - 4.7e-44 149.8 2.8 3.4e-43 147.0 2.8 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KPI43545.1 - 0.46 10.2 4.1 0.62 9.8 1.3 2.1 1 1 0 2 2 2 0 Tubulin binding cofactor C DEC-1_N PF04625.13 KPI43545.1 - 1.9 7.4 13.6 0.77 8.7 6.7 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.19 KPI43545.1 - 5.1 7.8 7.0 7.8 7.2 2.6 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein DUF917 PF06032.12 KPI43546.1 - 1.6e-113 379.1 2.2 2.7e-113 378.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KPI43546.1 - 1.6e-30 106.1 0.9 3e-27 95.5 0.1 2.9 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KPI43546.1 - 1.7e-22 80.0 10.3 3.1e-18 66.0 0.3 4.4 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase MutL PF13941.6 KPI43546.1 - 3.9e-07 29.0 1.1 0.0027 16.4 0.4 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 KPI43546.1 - 0.00047 19.7 0.1 0.00047 19.7 0.1 2.8 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KPI43546.1 - 0.0036 16.6 0.4 1.6 7.9 0.0 2.6 3 0 0 3 3 3 2 StbA protein FtsA PF14450.6 KPI43546.1 - 0.02 15.3 2.3 4.9 7.6 0.1 3.9 3 0 0 3 3 3 0 Cell division protein FtsA DLH PF01738.18 KPI43547.1 - 4.6e-19 68.8 0.0 5.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DAO PF01266.24 KPI43548.1 - 1.8e-46 159.4 0.1 3.8e-46 158.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 KPI43548.1 - 3.4e-35 120.7 0.0 6.8e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KPI43548.1 - 1.4e-08 34.2 1.2 0.00012 21.3 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KPI43548.1 - 6.7e-07 28.8 1.7 0.00049 19.4 0.1 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI43548.1 - 3.3e-05 23.4 0.1 6e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI43548.1 - 0.0014 18.8 0.3 0.0092 16.2 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI43548.1 - 0.0016 17.6 0.2 0.47 9.4 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KPI43548.1 - 0.0023 17.1 0.0 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPI43548.1 - 0.02 14.8 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KPI43548.1 - 0.024 13.4 0.2 0.037 12.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KPI43548.1 - 0.075 13.6 0.1 0.21 12.2 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI43548.1 - 0.085 12.1 0.1 0.25 10.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI43548.1 - 0.2 10.9 0.1 0.74 9.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Adeno_E3_CR2 PF02439.15 KPI43549.1 - 0.00074 19.2 1.2 0.0015 18.2 1.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DAP10 PF07213.11 KPI43549.1 - 0.0015 18.5 0.1 0.0037 17.2 0.1 1.6 1 0 0 1 1 1 1 DAP10 membrane protein CFEM PF05730.11 KPI43549.1 - 0.0018 18.3 5.2 0.0032 17.5 5.2 1.4 1 0 0 1 1 1 1 CFEM domain TMEM51 PF15345.6 KPI43549.1 - 0.036 13.9 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 KPI43549.1 - 0.14 13.0 0.0 0.29 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KPI43549.1 - 0.21 11.0 5.0 0.11 11.9 1.5 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KPI43549.1 - 1.6 8.7 4.8 0.69 9.8 1.3 2.2 2 1 0 2 2 2 0 TMEM154 protein family Neugrin PF06413.11 KPI43550.1 - 4.4e-07 30.2 0.0 4.4e-07 30.2 0.0 2.8 2 1 1 3 3 3 1 Neugrin MRP-L20 PF12824.7 KPI43550.1 - 3.7e-06 27.2 2.3 3.7e-06 27.2 2.3 2.5 2 1 2 4 4 4 1 Mitochondrial ribosomal protein subunit L20 IDO PF01231.18 KPI43551.1 - 6.5e-124 414.0 0.0 1.8e-86 290.6 0.0 3.0 1 1 2 3 3 3 3 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KPI43551.1 - 0.24 10.1 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) ABC_tran PF00005.27 KPI43552.1 - 4.4e-46 156.8 0.7 4.9e-22 78.9 0.0 3.0 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KPI43552.1 - 8.4e-22 77.0 3.0 8.4e-22 77.0 3.0 2.7 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KPI43552.1 - 1.3e-17 64.6 0.6 0.0033 17.3 0.4 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI43552.1 - 7.1e-10 38.7 0.2 0.74 9.2 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI43552.1 - 2.1e-08 33.8 0.3 0.0025 17.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KPI43552.1 - 8.1e-08 32.4 0.0 0.019 14.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 KPI43552.1 - 5.7e-07 30.1 0.0 0.0069 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KPI43552.1 - 2.6e-06 27.4 0.1 0.013 15.4 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KPI43552.1 - 4.8e-06 27.2 7.0 0.042 14.3 0.1 3.6 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 KPI43552.1 - 9.1e-06 26.2 0.2 0.21 12.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KPI43552.1 - 3e-05 24.1 0.0 0.033 14.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_27 PF13514.6 KPI43552.1 - 5.5e-05 22.8 0.0 0.013 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KPI43552.1 - 7.2e-05 23.1 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KPI43552.1 - 0.00018 21.9 0.3 1.7 9.1 0.0 3.8 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KPI43552.1 - 0.00078 19.8 0.0 2.7 8.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KPI43552.1 - 0.00083 19.6 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KPI43552.1 - 0.0012 18.8 1.5 0.73 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 KPI43552.1 - 0.0013 18.7 0.2 1.6 8.7 0.3 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KPI43552.1 - 0.0014 18.4 0.2 2.1 8.0 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KPI43552.1 - 0.0045 17.1 0.6 0.25 11.5 0.1 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KPI43552.1 - 0.0053 16.0 2.5 3.7 6.7 0.0 3.7 5 0 0 5 5 4 1 NB-ARC domain Roc PF08477.13 KPI43552.1 - 0.006 16.8 0.0 2.7 8.2 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KPI43552.1 - 0.008 16.2 0.1 5.2 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KPI43552.1 - 0.01 15.5 0.1 0.76 9.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 KPI43552.1 - 0.017 14.0 0.1 12 4.5 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DUF2813 PF11398.8 KPI43552.1 - 0.017 14.4 0.0 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 KPI43552.1 - 0.021 14.9 0.0 3.8 7.5 0.0 3.4 3 0 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 KPI43552.1 - 0.037 13.5 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KPI43552.1 - 0.054 12.7 0.0 3.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KPI43552.1 - 0.081 13.3 1.2 12 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KPI43552.1 - 0.082 12.8 0.3 8.4 6.2 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KPI43552.1 - 0.12 12.3 0.1 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 KPI43552.1 - 0.12 12.3 0.3 4.6 7.1 0.2 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KPI43552.1 - 0.12 12.1 0.3 5.6 6.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KPI43552.1 - 0.14 12.2 1.5 41 4.2 0.0 3.5 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 KPI43552.1 - 0.21 11.1 0.8 8 6.0 0.0 2.9 4 0 0 4 4 2 0 Ferrous iron transport protein B Pcc1 PF09341.10 KPI43553.1 - 8.1e-34 115.6 0.1 9.9e-34 115.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HhH-GPD PF00730.25 KPI43554.1 - 2.5e-18 66.5 0.0 4.5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KPI43554.1 - 5.7e-07 29.1 0.0 2.9e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_primase_lrg PF04104.14 KPI43555.1 - 2.2e-87 292.8 0.0 3.4e-87 292.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Flavin_Reduct PF01613.18 KPI43556.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavin reductase like domain PBP PF01161.20 KPI43557.1 - 1.4e-18 67.5 0.1 2.5e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF5353 PF17304.2 KPI43558.1 - 2e-30 104.3 2.7 2.7e-30 103.9 2.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF883 PF05957.13 KPI43558.1 - 0.0035 17.9 5.0 0.0073 16.9 5.0 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) DUF1490 PF07371.12 KPI43558.1 - 0.007 16.4 3.8 0.007 16.4 3.8 2.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1490) RR_TM4-6 PF06459.12 KPI43558.1 - 0.47 10.2 6.0 0.57 10.0 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM92 PF06730.11 KPI43558.1 - 0.49 9.8 5.9 0.68 9.3 5.9 1.2 1 0 0 1 1 1 0 FAM92 protein ISG65-75 PF11727.8 KPI43558.1 - 1.2 8.3 11.6 1.8 7.7 11.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein ETRAMP PF09716.10 KPI43558.1 - 1.6 8.8 4.9 2.8 8.1 4.9 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SAPS PF04499.15 KPI43558.1 - 1.7 7.3 4.8 1.9 7.2 4.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein vATP-synt_E PF01991.18 KPI43558.1 - 4.4 6.6 13.5 6.5 6.1 13.5 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Presenilin PF01080.17 KPI43558.1 - 5 5.8 4.5 5.3 5.7 4.5 1.1 1 0 0 1 1 1 0 Presenilin Pectate_lyase_3 PF12708.7 KPI43559.1 - 1.5e-55 188.3 10.4 5.4e-48 163.7 7.2 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KPI43559.1 - 0.0004 20.0 1.6 0.37 10.5 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase zf-CCCH PF00642.24 KPI43560.1 - 7.1e-10 38.5 4.3 7.2e-05 22.6 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPI43560.1 - 9.6e-10 38.2 10.0 1.5e-06 28.0 2.5 2.9 2 1 0 2 2 2 2 Zinc finger domain DUF1771 PF08590.10 KPI43560.1 - 3.3e-08 33.8 5.5 6.8e-08 32.8 5.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KPI43560.1 - 2.7e-07 30.8 0.1 7.5e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 KPI43560.1 - 7e-07 28.9 9.7 9.5e-06 25.3 0.7 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KPI43560.1 - 5.7e-06 26.6 4.2 0.015 15.8 0.3 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KPI43560.1 - 0.0015 18.7 2.3 1.1 9.4 0.1 2.4 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 KPI43560.1 - 0.0097 16.6 5.4 0.12 13.1 5.4 2.2 1 1 0 1 1 1 1 Torus domain HBS1_N PF08938.10 KPI43560.1 - 0.052 13.8 0.0 0.052 13.8 0.0 1.9 2 0 0 2 2 1 0 HBS1 N-terminus CUE PF02845.16 KPI43560.1 - 0.16 11.7 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 CUE domain SapB_1 PF05184.15 KPI43560.1 - 0.27 11.3 0.3 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 zf-C3H1 PF10650.9 KPI43560.1 - 0.6 9.9 3.4 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain CLASP_N PF12348.8 KPI43561.1 - 8.9e-34 117.0 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal p450 PF00067.22 KPI43562.1 - 1.2e-62 212.2 0.0 1.6e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHDPS PF00701.22 KPI43563.1 - 8.6e-31 106.7 0.0 1.1e-23 83.4 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family ANAPC5 PF12862.7 KPI43564.1 - 1.5e-36 124.3 2.0 5.3e-36 122.6 2.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 KPI43564.1 - 0.0012 18.6 0.1 1.6 8.4 0.0 3.2 3 0 0 3 3 3 2 26S proteasome subunit RPN7 TPR_19 PF14559.6 KPI43564.1 - 0.028 14.9 13.6 4.1 8.0 0.6 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI43564.1 - 0.029 14.6 7.4 1.6 9.1 0.5 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cohesin_load PF10345.9 KPI43564.1 - 0.039 12.4 1.4 0.38 9.1 0.0 2.2 2 0 0 2 2 2 0 Cohesin loading factor Cupin_2 PF07883.11 KPI43565.1 - 2.3e-11 43.2 0.3 3.7e-11 42.6 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Lyx_isomer PF07385.12 KPI43565.1 - 0.00035 19.9 0.0 0.018 14.3 0.0 2.0 1 1 1 2 2 2 2 D-lyxose isomerase AraC_binding PF02311.19 KPI43565.1 - 0.00092 19.1 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KPI43565.1 - 0.0073 16.2 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 KPI43565.1 - 0.031 14.0 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) TRAM PF01938.20 KPI43565.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 TRAM domain HAD_2 PF13419.6 KPI43566.1 - 7e-05 23.0 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI43566.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like PNK3P PF08645.11 KPI43566.1 - 0.033 13.9 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase HCO3_cotransp PF00955.21 KPI43567.1 - 8.1e-74 249.3 17.2 9.8e-45 153.3 5.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family RexB PF15968.5 KPI43567.1 - 0.035 14.6 0.4 0.035 14.6 0.4 2.5 2 0 0 2 2 2 0 Membrane-anchored ion channel, Abi component Glyco_hydro_32N PF00251.20 KPI43568.1 - 1e-43 150.0 0.2 1.7e-43 149.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KPI43568.1 - 4e-08 33.4 0.7 6.5e-08 32.7 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KPI43568.1 - 0.054 13.5 0.2 0.45 10.7 0.2 2.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Pollen_allerg_1 PF01357.21 KPI43568.1 - 2.2 8.4 7.5 1.1 9.3 0.4 3.4 4 0 0 4 4 4 0 Pollen allergen UPF0193 PF05250.11 KPI43569.1 - 0.28 10.9 0.0 0.43 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) PPR_2 PF13041.6 KPI43570.1 - 4.4e-20 71.6 2.0 1e-11 44.9 0.0 5.9 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.20 KPI43570.1 - 1.8e-16 59.1 4.9 0.0017 18.4 0.0 8.3 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.7 KPI43570.1 - 1.8e-12 46.7 0.3 0.0094 15.6 0.0 5.3 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.6 KPI43570.1 - 6.7e-11 42.1 0.3 6.4e-05 23.0 0.0 4.7 1 1 5 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 KPI43570.1 - 1e-09 38.1 1.7 1.5e-05 24.5 0.3 3.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KPI43570.1 - 0.0011 19.5 1.1 5.2 7.7 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ATP13 PF12921.7 KPI43570.1 - 0.012 15.4 0.2 0.29 11.0 0.0 2.5 1 1 1 2 2 2 0 Mitochondrial ATPase expression AEP1 PF17049.5 KPI43570.1 - 0.042 12.9 0.1 4.1 6.4 0.0 2.9 2 1 1 3 3 3 0 ATPase expression protein 1 RNase_PH PF01138.21 KPI43571.1 - 1.1e-08 35.7 0.0 1.5e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Npun_R1517 PF18068.1 KPI43571.1 - 0.042 14.2 0.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Npun R1517 SAICAR_synt PF01259.18 KPI43572.1 - 1.6e-90 303.1 0.0 1.8e-50 171.9 0.0 2.0 1 1 1 2 2 2 2 SAICAR synthetase Glyco_transf_41 PF13844.6 KPI43573.1 - 3.1e-96 322.7 0.2 1e-46 159.4 0.0 4.0 4 0 0 4 4 4 3 Glycosyl transferase family 41 TPR_2 PF07719.17 KPI43573.1 - 8.4e-18 63.0 10.0 0.00034 20.5 0.3 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KPI43573.1 - 8.9e-17 60.1 11.8 0.00019 21.1 0.1 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KPI43573.1 - 2.2e-13 49.7 17.5 0.002 17.8 0.6 6.5 3 2 3 6 6 6 4 TPR repeat TPR_8 PF13181.6 KPI43573.1 - 8.4e-12 44.3 6.7 0.0059 16.7 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KPI43573.1 - 6.8e-11 42.1 6.2 0.014 16.2 0.1 6.3 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KPI43573.1 - 6.9e-11 41.7 13.1 0.0012 18.6 1.6 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KPI43573.1 - 1.3e-10 40.9 5.6 0.19 12.1 0.3 5.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPI43573.1 - 5.3e-10 39.4 9.9 0.0004 20.6 3.7 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KPI43573.1 - 5.5e-10 39.6 7.3 0.00017 22.1 2.4 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KPI43573.1 - 5.9e-10 39.6 8.7 4.7e-05 23.9 2.7 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KPI43573.1 - 8e-08 31.8 5.6 0.0052 16.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 KPI43573.1 - 8e-05 23.1 1.4 0.077 13.4 0.0 2.9 2 0 0 2 2 2 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KPI43573.1 - 0.007 16.6 2.9 0.091 13.0 1.3 3.1 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KPI43573.1 - 0.018 14.3 1.4 0.7 9.1 1.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KPI43573.1 - 0.051 13.7 3.8 5.6 7.2 0.0 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KPI43573.1 - 1.6 9.6 7.7 65 4.5 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KPI43573.1 - 1.7 9.5 6.2 4.9 8.1 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat MS_channel PF00924.18 KPI43574.1 - 1.4e-17 63.9 0.6 3.1e-17 62.8 0.6 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KPI43574.1 - 0.0073 15.8 0.8 0.015 14.8 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KPI43574.1 - 0.019 14.4 0.2 0.045 13.3 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KPI43574.1 - 0.069 13.1 0.2 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Bac_export_2 PF01312.19 KPI43574.1 - 5.6 6.1 5.5 21 4.2 0.1 2.5 2 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family Fungal_trans_2 PF11951.8 KPI43575.1 - 6.2e-42 143.8 5.4 9.4e-42 143.2 5.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.20 KPI43576.1 - 9e-79 265.1 0.0 1e-78 264.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_3 PF07859.13 KPI43577.1 - 5.8e-33 114.5 0.0 8.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KPI43577.1 - 4.9e-05 22.4 0.0 7.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPI43577.1 - 0.18 11.3 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_4 PF02390.17 KPI43577.1 - 0.28 10.6 0.5 0.6 9.6 0.5 1.4 1 0 0 1 1 1 0 Putative methyltransferase WD40 PF00400.32 KPI43579.1 - 4.5e-29 100.1 19.5 3e-06 27.8 0.1 8.4 9 0 0 9 9 9 5 WD domain, G-beta repeat F-box-like PF12937.7 KPI43579.1 - 7.1e-09 35.4 1.3 1.6e-08 34.3 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI43579.1 - 5.7e-08 32.4 0.6 1.5e-07 31.1 0.6 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KPI43579.1 - 8.7e-07 29.2 0.1 0.65 10.3 0.1 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KPI43579.1 - 0.00063 19.6 0.1 0.0029 17.5 0.0 2.2 2 0 0 2 2 2 1 F-box PALB2_WD40 PF16756.5 KPI43579.1 - 0.039 12.9 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KPI43579.1 - 0.055 12.1 0.5 5.4 5.5 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Kelch_6 PF13964.6 KPI43579.1 - 0.25 11.7 1.2 8.6 6.8 0.1 3.4 4 0 0 4 4 4 0 Kelch motif S10_plectin PF03501.15 KPI43580.1 - 9.4e-42 141.0 0.1 1.1e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain MFS_1 PF07690.16 KPI43581.1 - 8.8e-15 54.5 31.9 1.2e-07 31.1 7.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI43581.1 - 0.00089 18.2 14.8 0.00094 18.2 0.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KPI43581.1 - 0.0043 16.0 3.1 0.0043 16.0 3.1 2.2 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 KPI43581.1 - 0.0097 14.5 14.3 0.037 12.6 2.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3796 PF12676.7 KPI43581.1 - 0.13 12.7 3.2 0.4 11.1 3.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Ank_4 PF13637.6 KPI43582.1 - 1.3e-10 41.6 0.4 3e-06 27.7 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KPI43582.1 - 2.7e-07 31.1 0.1 6e-06 26.8 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPI43582.1 - 1.3e-05 25.2 0.3 0.00019 21.6 0.1 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KPI43582.1 - 3.6e-05 24.0 0.3 0.00095 19.5 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KPI43582.1 - 0.00012 22.3 0.0 0.00035 20.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) UcrQ PF02939.16 KPI43583.1 - 5.8e-35 119.1 0.1 7.1e-35 118.8 0.1 1.1 1 0 0 1 1 1 1 UcrQ family zf-C2H2 PF00096.26 KPI43585.1 - 6.9e-06 26.2 13.5 0.0098 16.3 1.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI43585.1 - 0.66 11.0 15.8 5.4 8.1 2.5 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPI43585.1 - 2.2 8.9 19.7 2.7 8.6 0.3 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Pex14_N PF04695.13 KPI43586.1 - 2.6e-32 112.7 0.9 2.6e-32 112.7 0.9 3.2 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ALMT PF11744.8 KPI43586.1 - 0.44 9.3 1.9 0.72 8.6 1.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter PhyH PF05721.13 KPI43589.1 - 3.2e-28 99.4 0.1 4.5e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KPI43589.1 - 0.00091 19.6 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KPI43589.1 - 0.034 15.0 0.0 0.071 14.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Crystall PF00030.19 KPI43589.1 - 0.048 13.9 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Mit_KHE1 PF10173.9 KPI43591.1 - 1.2e-37 129.9 0.0 2.3e-37 128.9 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Nab2 PF11517.8 KPI43593.1 - 5.7e-05 23.3 0.6 0.00016 21.9 0.2 2.0 2 1 0 2 2 2 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_tran_WbsX PF14307.6 KPI43594.1 - 3.3e-57 194.5 11.0 2.6e-31 109.3 0.2 3.1 1 1 2 3 3 3 3 Glycosyltransferase WbsX Tmemb_cc2 PF10267.9 KPI43597.1 - 1.1 8.4 3.4 1.8 7.6 3.4 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ribosomal_L22e PF01776.17 KPI43598.1 - 1.7e-48 163.5 0.3 2.1e-48 163.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Cation_ATPase_C PF00689.21 KPI43599.1 - 2.9e-46 157.4 4.8 2.9e-46 157.4 4.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPI43599.1 - 2.1e-35 121.9 0.1 2.1e-35 121.9 0.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPI43599.1 - 3.5e-20 71.9 0.0 6.7e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPI43599.1 - 5.7e-19 69.2 0.2 1.4e-18 68.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPI43599.1 - 1.2e-06 28.5 0.4 0.00022 21.0 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI43599.1 - 5.1e-06 26.1 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF1774 PF08611.10 KPI43599.1 - 0.19 12.1 2.2 0.58 10.5 0.1 2.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) His_Phos_1 PF00300.22 KPI43600.1 - 2.8e-30 105.5 0.0 4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) VD10_N PF08476.10 KPI43600.1 - 0.093 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Viral D10 N-terminal GAF_2 PF13185.6 KPI43601.1 - 6.6e-13 49.1 0.0 9.4e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KPI43601.1 - 1.3e-07 32.3 0.0 1.3e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain BAR PF03114.18 KPI43602.1 - 1.1e-64 218.3 4.3 1.5e-64 217.9 4.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KPI43602.1 - 3e-15 55.6 0.1 6.1e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI43602.1 - 8.3e-11 41.6 0.1 1.5e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KPI43602.1 - 6.8e-09 35.3 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APG6_N PF17675.1 KPI43602.1 - 0.41 11.2 9.2 2.1 8.9 4.7 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4430 PF14478.6 KPI43602.1 - 1.6 9.4 4.8 9.5 6.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4430) TMPIT PF07851.13 KPI43602.1 - 2.2 7.4 5.4 4.4 6.5 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein Sugar_tr PF00083.24 KPI43603.1 - 2.6e-129 432.0 18.5 3.2e-129 431.7 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43603.1 - 4.3e-23 81.8 31.6 3.1e-16 59.3 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KPI43603.1 - 0.34 11.2 4.7 0.43 10.8 1.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) DASH_Ask1 PF08655.10 KPI43604.1 - 2.6e-30 104.1 0.1 4.1e-30 103.5 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 UQ_con PF00179.26 KPI43605.1 - 1.6e-36 125.1 0.0 1.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 KPI43605.1 - 0.013 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 KPI43605.1 - 0.014 15.7 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain PolyA_pol_RNAbd PF12627.7 KPI43605.1 - 0.22 11.3 0.0 0.43 10.4 0.0 1.5 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Hexapep PF00132.24 KPI43606.1 - 1.4e-11 43.6 3.8 4e-05 23.2 0.2 4.5 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPI43606.1 - 4.6e-05 23.1 2.8 1.5 8.7 3.4 4.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Glucosamine_iso PF01182.20 KPI43607.1 - 2.3e-19 70.2 0.0 3.6e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Phosphatase PF15698.5 KPI43607.1 - 0.028 13.5 0.4 0.096 11.8 0.4 1.8 1 1 0 1 1 1 0 Phosphatase Ribosomal_L5e PF17144.4 KPI43608.1 - 2.7e-78 261.6 0.1 4.4e-78 260.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KPI43608.1 - 1.6e-34 118.7 11.0 1.6e-34 118.7 11.0 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region PEX-1N PF09262.11 KPI43609.1 - 0.045 14.2 1.2 0.2 12.1 1.2 2.1 1 1 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Ndc1_Nup PF09531.10 KPI43609.1 - 1.5 7.4 5.4 1.9 7.1 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 KPI43609.1 - 2.2 7.4 15.5 2.5 7.2 15.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KPI43609.1 - 2.6 7.9 7.0 3.3 7.5 7.0 1.1 1 0 0 1 1 1 0 SPX domain DUF2486 PF10667.9 KPI43609.1 - 4.4 7.4 14.6 2.3 8.4 10.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Hamartin PF04388.12 KPI43609.1 - 8.6 4.9 12.0 11 4.5 12.0 1.3 1 0 0 1 1 1 0 Hamartin protein Med21 PF11221.8 KPI43610.1 - 3.2e-37 128.0 0.9 3.8e-37 127.7 0.9 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex MRP-L20 PF12824.7 KPI43610.1 - 0.00093 19.4 0.6 0.0012 19.1 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DEAD PF00270.29 KPI43611.1 - 4.6e-35 121.0 0.3 1.2e-33 116.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI43611.1 - 5.9e-23 81.3 0.2 1.4e-22 80.1 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI43611.1 - 5.9e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2999 PF11212.8 KPI43611.1 - 0.16 12.3 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Transp_cyt_pur PF02133.15 KPI43612.1 - 3e-78 263.6 42.2 4.4e-77 259.7 42.2 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 KPI43612.1 - 4.4e-21 75.1 3.4 6.5e-21 74.6 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43612.1 - 0.00088 19.3 8.9 0.0016 18.5 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 KPI43615.1 - 1.1e-40 140.3 0.1 1.5e-40 139.9 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Cupin_1 PF00190.22 KPI43616.1 - 6.3e-06 25.9 0.2 9.2e-06 25.3 0.2 1.3 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPI43616.1 - 7.2e-06 25.6 0.3 1.3e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KPI43616.1 - 0.00029 20.6 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KPI43616.1 - 0.063 13.2 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 KPI43616.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_2 PF07883.11 KPI43618.1 - 2.2e-09 36.9 0.4 3.4e-09 36.3 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPI43618.1 - 0.0019 17.8 0.0 0.0024 17.5 0.0 1.3 1 1 0 1 1 1 1 Cupin DUF596 PF04591.12 KPI43618.1 - 0.035 14.2 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Ectoine_synth PF06339.12 KPI43618.1 - 0.06 13.5 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Ectoine synthase Fungal_trans PF04082.18 KPI43620.1 - 2.8e-11 43.0 0.6 5.1e-11 42.1 0.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C4H2 PF10146.9 KPI43621.1 - 0.53 10.5 7.2 0.66 10.2 7.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF996 PF06195.13 KPI43622.1 - 0.25 11.6 7.0 3.7 7.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) S_4TM PF18159.1 KPI43622.1 - 1.5 8.1 8.7 1.3 8.3 3.2 2.5 2 1 0 2 2 2 0 SMODS-associating 4TM effector domain DUF4013 PF13197.6 KPI43622.1 - 2.9 7.7 12.3 0.18 11.6 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4013) Pex24p PF06398.11 KPI43623.1 - 1.8e-75 254.2 0.0 2.4e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Exo70 PF03081.15 KPI43624.1 - 3.5e-62 210.6 0.0 7.9e-62 209.5 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Syntaxin PF00804.25 KPI43624.1 - 1.6 8.3 5.1 9.9 5.8 0.3 2.7 3 0 0 3 3 3 0 Syntaxin muHD PF10291.9 KPI43625.1 - 2.1e-72 243.7 0.0 2.8e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KPI43625.1 - 1.2e-05 25.5 0.1 5.4e-05 23.4 0.0 2.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain MRP-S31 PF15433.6 KPI43625.1 - 0.3 10.7 4.1 0.63 9.7 4.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Fungal_trans PF04082.18 KPI43626.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.24 KPI43627.1 - 1.2e-62 212.3 11.0 1.9e-62 211.6 11.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43627.1 - 7.8e-14 51.4 22.4 7.8e-14 51.4 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI43627.1 - 0.37 9.6 12.7 0.027 13.4 3.6 2.2 2 0 0 2 2 2 0 MFS_1 like family PTH2 PF01981.16 KPI43628.1 - 2.3e-41 140.7 0.1 3.8e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Cwf_Cwc_15 PF04889.12 KPI43628.1 - 0.013 15.2 0.7 0.017 14.9 0.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RFC1 PF08519.12 KPI43629.1 - 1.3e-58 197.6 0.1 2.2e-58 196.9 0.1 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Nucleo_P87 PF07267.11 KPI43629.1 - 0.0067 15.3 1.0 0.0091 14.9 1.0 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 AAA_assoc_2 PF16193.5 KPI43629.1 - 0.067 13.5 0.4 7.2 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA C-terminal domain CBM32 PF18344.1 KPI43629.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Troponin PF00992.20 KPI43629.1 - 0.34 11.2 6.8 0.75 10.1 6.8 1.5 1 0 0 1 1 1 0 Troponin Pox_Ag35 PF03286.14 KPI43629.1 - 0.61 9.8 11.4 1.3 8.8 11.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTPRCAP PF15713.5 KPI43629.1 - 9.9 6.4 13.4 24 5.2 13.4 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Peptidase_M22 PF00814.25 KPI43630.1 - 1.1e-43 149.9 0.0 8.6e-42 143.7 0.0 2.8 1 1 0 1 1 1 1 Glycoprotease family RTA1 PF04479.13 KPI43631.1 - 2.8e-60 203.5 9.7 2.8e-60 203.5 9.7 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF588 PF04535.12 KPI43631.1 - 5e-07 29.6 2.7 8.7e-06 25.6 0.4 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF588) COX6A PF02046.15 KPI43632.1 - 7.5e-54 181.0 0.4 8.8e-54 180.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CtaG_Cox11 PF04442.14 KPI43633.1 - 2.4e-61 206.2 0.1 3.6e-61 205.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 CHCH PF06747.13 KPI43634.1 - 0.00031 20.8 3.9 0.00049 20.2 3.9 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KPI43634.1 - 0.001 19.0 1.7 0.0016 18.4 1.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Trypan_glycop_C PF10659.9 KPI43634.1 - 0.035 14.5 0.3 0.048 14.0 0.3 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Glyco_hydro_44 PF12891.7 KPI43634.1 - 0.048 13.6 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 DUF2076 PF09849.9 KPI43634.1 - 0.05 13.7 18.8 0.17 11.9 18.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Peptidase_C97 PF05903.14 KPI43636.1 - 1.2e-05 25.2 0.8 2.1e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.13 KPI43636.1 - 0.015 15.6 1.2 0.69 10.2 1.2 2.6 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF778 PF05608.12 KPI43636.1 - 0.026 14.9 0.1 0.026 14.9 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF778) DUF4105 PF13387.6 KPI43636.1 - 0.077 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) DUF4796 PF16044.5 KPI43636.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) AA_permease PF00324.21 KPI43637.1 - 4e-82 276.3 37.9 1.5e-56 192.0 16.2 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KPI43637.1 - 9e-24 84.1 33.8 1.1e-16 60.8 17.0 2.0 2 0 0 2 2 2 2 Amino acid permease 4HBT PF03061.22 KPI43638.1 - 0.022 15.1 0.1 0.1 13.0 0.1 2.0 1 1 0 1 1 1 0 Thioesterase superfamily MFS_1 PF07690.16 KPI43639.1 - 8.5e-43 146.6 34.7 5.9e-40 137.3 18.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI43639.1 - 8.2e-07 28.2 14.8 8.2e-07 28.2 14.8 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter MMM1 PF10296.9 KPI43640.1 - 7.3e-05 22.0 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Drf_GBD PF06371.13 KPI43641.1 - 4e-14 52.6 4.9 7.8e-09 35.4 0.0 3.1 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain BROMI PF14961.6 KPI43641.1 - 0.093 10.1 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein Glyco_tranf_2_3 PF13641.6 KPI43642.1 - 9.5e-18 64.9 0.0 1.4e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KPI43642.1 - 1.2e-13 51.4 0.1 3.2e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KPI43642.1 - 5.7e-11 42.2 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KPI43642.1 - 1.4e-08 34.8 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KPI43642.1 - 1.7e-08 33.5 0.8 0.0027 16.3 0.3 2.1 1 1 1 2 2 2 2 Cellulose synthase Acyl_transf_3 PF01757.22 KPI43643.1 - 2e-11 43.6 4.5 2e-11 43.6 4.5 3.3 4 0 0 4 4 4 3 Acyltransferase family DUF1772 PF08592.11 KPI43644.1 - 3.9e-05 24.0 1.6 4.6e-05 23.8 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) CENP-B_dimeris PF09026.10 KPI43645.1 - 0.2 12.1 8.7 0.5 10.8 7.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KPI43645.1 - 0.24 11.1 2.3 0.37 10.4 2.3 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KPI43645.1 - 0.51 9.6 5.9 0.71 9.1 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KPI43645.1 - 7 4.6 6.8 9 4.3 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DLH PF01738.18 KPI43647.1 - 1.4e-11 44.3 0.4 1e-10 41.6 0.4 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF202 PF02656.15 KPI43648.1 - 9.9e-20 70.8 3.3 9.9e-20 70.8 3.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF202) PIN_3 PF13470.6 KPI43649.1 - 0.11 13.3 0.9 0.18 12.6 0.2 1.6 1 1 1 2 2 2 0 PIN domain Acetyltransf_10 PF13673.7 KPI43650.1 - 0.00033 20.6 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KPI43650.1 - 0.0016 18.7 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI43650.1 - 0.0063 16.9 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI43650.1 - 0.025 14.7 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI43650.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PAN_4 PF14295.6 KPI43652.1 - 0.017 15.1 4.7 0.073 13.0 4.7 2.1 1 0 0 1 1 1 0 PAN domain CBF PF03914.17 KPI43653.1 - 4.6e-26 91.9 0.5 1.3e-23 83.9 0.0 3.0 2 1 2 4 4 4 2 CBF/Mak21 family Zn_clus PF00172.18 KPI43654.1 - 2.8e-05 24.1 10.5 5.6e-05 23.2 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dicty_CAR PF05462.11 KPI43655.1 - 4.8e-13 48.9 4.7 4.8e-13 48.9 4.7 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KPI43655.1 - 3.5e-05 23.7 7.0 6.8e-05 22.7 7.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF4663 PF15668.5 KPI43655.1 - 0.68 8.9 2.7 1.3 8.1 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) MMR_HSR1 PF01926.23 KPI43656.1 - 2.9e-15 56.3 0.0 7.6e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KPI43656.1 - 0.0004 20.0 0.0 0.0036 16.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KPI43656.1 - 0.00042 20.3 0.4 0.0038 17.1 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 KPI43656.1 - 0.0051 16.3 0.1 0.0098 15.4 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KPI43656.1 - 0.015 14.7 0.0 0.042 13.3 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KPI43656.1 - 0.022 14.8 0.0 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KPI43656.1 - 0.075 13.3 0.3 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GATA PF00320.27 KPI43656.1 - 0.22 11.2 1.9 0.61 9.7 0.1 2.4 2 0 0 2 2 2 0 GATA zinc finger Fungal_trans PF04082.18 KPI43658.1 - 6.7e-07 28.6 1.0 2.6e-06 26.7 0.4 2.2 1 1 0 2 2 2 1 Fungal specific transcription factor domain CAML PF14963.6 KPI43659.1 - 1.6 8.8 5.9 3.3 7.8 5.9 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Macoilin PF09726.9 KPI43659.1 - 9.7 4.6 5.9 13 4.2 5.9 1.1 1 0 0 1 1 1 0 Macoilin family AT_hook PF02178.19 KPI43660.1 - 4.4 7.5 12.4 0.13 12.2 3.8 3.3 2 0 0 2 2 2 0 AT hook motif Suppressor_APC PF11414.8 KPI43661.1 - 0.011 15.8 2.3 0.027 14.5 2.3 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Ax_dynein_light PF10211.9 KPI43661.1 - 0.022 14.7 5.0 0.022 14.7 5.0 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain EndoU_bacteria PF14436.6 KPI43661.1 - 0.13 12.6 3.6 0.091 13.1 1.6 1.7 2 0 0 2 2 2 0 Bacterial EndoU nuclease GAS PF13851.6 KPI43661.1 - 4.7 6.5 16.8 0.41 10.0 3.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Zn_clus PF00172.18 KPI43662.1 - 4.1e-09 36.4 6.7 8.3e-09 35.4 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI43662.1 - 1.6e-05 23.9 0.1 3.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rx_N PF18052.1 KPI43663.1 - 0.011 16.0 2.5 0.78 10.1 0.4 2.4 1 1 1 2 2 2 0 Rx N-terminal domain ApoO PF09769.9 KPI43663.1 - 0.16 11.9 0.4 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein O FPV060 PF17614.2 KPI43663.1 - 0.17 11.2 0.1 0.3 10.5 0.1 1.3 1 0 0 1 1 1 0 Viral CC-type chemokine G-alpha PF00503.20 KPI43664.1 - 5.9e-109 364.5 2.4 2e-94 316.7 0.3 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KPI43664.1 - 6.6e-16 58.3 1.0 1.3e-10 41.1 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KPI43664.1 - 0.00035 20.3 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KPI43664.1 - 0.0051 16.2 5.0 0.027 13.8 0.2 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KPI43664.1 - 0.034 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KPI43664.1 - 0.041 13.0 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 KPI43664.1 - 0.073 13.3 3.7 3.9 7.7 0.2 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KPI43664.1 - 0.099 12.7 0.1 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KPI43664.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-AN1 PF01428.16 KPI43665.1 - 3.3e-10 40.0 4.4 4.6e-10 39.5 4.4 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KPI43665.1 - 0.00038 20.2 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Transp_Tc5_C PF04236.15 KPI43665.1 - 0.005 17.2 0.3 0.0078 16.5 0.3 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain Hamartin PF04388.12 KPI43665.1 - 0.022 13.4 1.6 0.021 13.5 1.6 1.1 1 0 0 1 1 1 0 Hamartin protein DOCK_N PF16172.5 KPI43666.1 - 1.7e-65 221.4 0.0 2.9e-64 217.3 0.0 2.2 1 1 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KPI43666.1 - 4.9e-28 98.3 0.0 8.4e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 KPI43666.1 - 4.5e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI43666.1 - 0.024 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Period_C PF12114.8 KPI43666.1 - 0.2 11.2 1.3 1.3 8.5 0.9 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region NAD_kinase PF01513.21 KPI43669.1 - 1.2e-62 211.7 0.0 4.3e-48 164.0 0.0 2.1 1 1 1 2 2 2 2 ATP-NAD kinase ETF PF01012.21 KPI43670.1 - 8.9e-43 146.3 0.1 1.3e-42 145.7 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KPI43670.1 - 2.3e-19 69.2 0.3 1.9e-17 63.0 0.3 2.6 1 1 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Dynamin_M PF01031.20 KPI43671.1 - 1.5e-110 368.9 0.0 3.5e-110 367.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KPI43671.1 - 4.4e-57 192.8 0.8 1.1e-56 191.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KPI43671.1 - 2.2e-32 111.1 1.3 5.5e-32 109.8 1.3 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KPI43671.1 - 6.6e-05 23.0 0.5 0.0019 18.3 0.5 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 KPI43672.1 - 5.5e-37 127.5 51.2 5.5e-37 127.5 51.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI43672.1 - 3.3e-11 42.3 23.6 2.2e-10 39.6 23.6 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Viral_Beta_CD PF04530.12 KPI43672.1 - 0.063 13.6 1.2 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Viral Beta C/D like family Chitin_synth_2 PF03142.15 KPI43673.1 - 1.7e-247 822.2 1.4 2.2e-247 821.8 1.4 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KPI43673.1 - 5.9e-72 242.9 0.0 4.8e-71 239.9 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KPI43673.1 - 3.4e-14 52.7 0.2 2.6e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KPI43673.1 - 2.3e-13 49.8 0.3 6.6e-13 48.4 0.3 1.9 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KPI43673.1 - 3.3e-11 43.5 3.9 3.3e-11 43.5 3.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPI43673.1 - 4.1e-10 39.9 0.0 8.8e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KPI43673.1 - 0.00012 21.9 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPI43673.1 - 0.027 13.9 0.1 0.38 10.2 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 21 RsgA_GTPase PF03193.16 KPI43673.1 - 0.069 13.1 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KPI43673.1 - 0.077 13.4 0.9 0.51 10.7 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain Med16 PF11635.8 KPI43674.1 - 7.7e-05 20.8 0.1 7.7e-05 20.8 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 fn1 PF00039.18 KPI43674.1 - 0.035 14.3 0.9 0.077 13.2 0.9 1.5 1 0 0 1 1 1 0 Fibronectin type I domain DUF35_N PF12172.8 KPI43674.1 - 0.13 12.1 1.3 0.47 10.4 0.1 2.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) GATase_7 PF13537.6 KPI43675.1 - 5.7e-07 29.5 0.0 4.5e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KPI43675.1 - 2.8e-05 24.3 0.0 0.00019 21.7 0.0 2.2 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KPI43675.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein AAT PF03417.16 KPI43676.1 - 7e-22 78.2 0.0 9e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Gly_transf_sug PF04488.15 KPI43677.1 - 1.7e-11 44.6 0.0 3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KPI43677.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein MFS_1 PF07690.16 KPI43678.1 - 8.9e-36 123.5 32.1 1.7e-35 122.6 32.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ish1 PF10281.9 KPI43679.1 - 3.9e-85 279.8 20.7 3.9e-14 52.7 0.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KPI43679.1 - 5.5e-14 51.6 0.3 0.00029 20.5 0.1 4.9 4 0 0 4 4 4 3 HeH/LEM domain SAP PF02037.27 KPI43679.1 - 1.3e-12 47.1 0.0 0.84 9.5 0.0 7.7 7 1 1 8 8 8 3 SAP domain ANAPC2 PF08672.11 KPI43679.1 - 6.1e-05 23.5 0.5 77 3.9 0.0 5.9 7 0 0 7 7 6 0 Anaphase promoting complex (APC) subunit 2 Thymopoietin PF08198.11 KPI43679.1 - 0.00019 21.0 0.0 7.6 6.2 0.0 4.0 4 0 0 4 4 4 2 Thymopoietin protein Slx4 PF09494.10 KPI43679.1 - 0.00039 20.3 0.2 18 5.4 0.0 6.0 7 0 0 7 7 7 0 Slx4 endonuclease Endonuc-dimeris PF09124.10 KPI43679.1 - 0.00085 19.4 0.1 12 6.1 0.0 4.2 5 0 0 5 5 5 0 T4 recombination endonuclease VII, dimerisation DUF3612 PF12268.8 KPI43679.1 - 0.0018 18.4 0.1 13 5.8 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3612) DUF4518 PF15008.6 KPI43679.1 - 0.0055 15.9 2.2 13 4.8 1.0 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4518) Homeobox_KN PF05920.11 KPI43679.1 - 0.04 13.8 0.0 14 5.7 0.1 4.0 4 0 0 4 4 4 0 Homeobox KN domain YtxH PF12732.7 KPI43679.1 - 0.65 10.6 8.2 0.86 10.2 3.7 3.4 4 0 0 4 4 4 0 YtxH-like protein SAP30_Sin3_bdg PF13867.6 KPI43679.1 - 4.8 7.6 4.8 24 5.4 0.0 3.8 5 0 0 5 5 5 0 Sin3 binding region of histone deacetylase complex subunit SAP30 SLATT_4 PF18186.1 KPI43679.1 - 5.9 6.5 11.0 0.13 11.9 2.9 2.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF2795 PF11387.8 KPI43679.1 - 6.3 7.1 6.1 20 5.5 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) SAM_2 PF07647.17 KPI43679.1 - 6.8 6.9 6.2 1.5e+02 2.6 0.0 4.5 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) Sld5 PF05916.11 KPI43680.1 - 8.9e-14 51.9 0.2 1.3e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein DUF4081 PF13312.6 KPI43680.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) zf-MYND PF01753.18 KPI43681.1 - 2.7e-08 33.8 6.9 5e-08 32.9 6.9 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KPI43681.1 - 8.5 6.3 8.5 1.6 8.7 4.7 1.8 2 0 0 2 2 2 0 HIT zinc finger dsDNA_bind PF01984.20 KPI43682.1 - 6.2e-35 119.8 13.5 6.2e-35 119.8 13.5 1.4 1 1 1 2 2 2 1 Double-stranded DNA-binding domain DUF4615 PF15393.6 KPI43682.1 - 0.68 10.5 5.6 0.47 11.0 3.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) GAT PF03127.14 KPI43683.1 - 5e-17 62.0 0.5 1e-16 61.0 0.5 1.5 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 KPI43683.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 2 0 0 2 2 2 1 VHS domain FHA PF00498.26 KPI43684.1 - 2.5e-15 56.6 0.0 4.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPI43684.1 - 5.1e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 KPI43684.1 - 0.0014 18.2 0.3 0.0031 17.1 0.0 1.6 2 0 0 2 2 2 1 YhfZ C-terminal domain KxDL PF10241.9 KPI43684.1 - 1.2 9.4 7.2 32 4.9 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein Jnk-SapK_ap_N PF09744.9 KPI43684.1 - 2.8 8.1 17.6 4.3 7.5 5.0 3.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF3349 PF11829.8 KPI43684.1 - 5 8.0 9.4 6.2 7.7 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) DUF1515 PF07439.11 KPI43684.1 - 5.3 7.1 8.5 0.33 11.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) CDC73_C PF05179.14 KPI43685.1 - 8.5e-54 181.5 0.1 1.2e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal eIF-5a PF01287.20 KPI43686.1 - 2e-27 95.0 4.0 2.9e-27 94.6 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Nitro_FeMo-Co PF02579.17 KPI43686.1 - 0.0019 18.5 0.2 0.0072 16.6 0.1 1.9 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor EFP_N PF08207.12 KPI43686.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-H2C2_2 PF13465.6 KPI43687.1 - 2.4 8.7 6.3 0.75 10.3 1.6 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DUF3431 PF11913.8 KPI43688.1 - 6e-85 284.4 0.1 7.8e-85 284.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Fungal_trans_2 PF11951.8 KPI43689.1 - 4.5e-44 150.8 8.6 5.4e-44 150.6 8.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NESP55 PF06390.12 KPI43689.1 - 0.36 10.4 1.4 11 5.5 0.0 3.1 3 1 1 4 4 4 0 Neuroendocrine-specific golgi protein P55 (NESP55) Fungal_trans_2 PF11951.8 KPI43690.1 - 6.2e-11 41.7 0.1 9.3e-11 41.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43690.1 - 1.8e-08 34.4 5.7 3.1e-08 33.6 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_ATPase_C PF00689.21 KPI43692.1 - 1.3e-46 158.6 11.3 1.3e-46 158.6 11.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KPI43692.1 - 1.3e-36 125.8 0.1 1.3e-36 125.8 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KPI43692.1 - 1.6e-19 69.7 0.0 3.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KPI43692.1 - 7.7e-18 65.5 1.6 4.3e-17 63.1 1.6 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI43692.1 - 4.8e-11 42.2 0.3 3.5e-09 36.2 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KPI43692.1 - 0.0016 18.2 0.1 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPI43692.1 - 0.11 12.9 0.0 0.57 10.6 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KPI43692.1 - 0.45 10.4 2.2 0.97 9.4 0.1 2.5 2 0 0 2 2 2 0 Ferlin C-terminus Sugar_tr PF00083.24 KPI43693.1 - 2.1e-76 257.6 22.3 2.4e-76 257.4 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43693.1 - 7.1e-27 94.3 29.6 1.4e-23 83.4 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI43693.1 - 1e-07 30.8 0.7 1e-07 30.8 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KPI43693.1 - 1.9e-06 26.7 0.8 1.9e-06 26.7 0.8 2.6 2 0 0 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.19 KPI43693.1 - 0.0007 18.5 0.2 0.0007 18.5 0.2 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF4293 PF14126.6 KPI43693.1 - 0.1 12.9 2.6 0.29 11.4 2.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2108 PF09881.9 KPI43693.1 - 1.2 9.2 7.7 0.062 13.3 2.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) HhH-GPD PF00730.25 KPI43694.1 - 1.1e-11 45.1 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TSSC4 PF15264.6 KPI43694.1 - 0.092 13.0 0.5 0.17 12.2 0.5 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 S_4TM PF18159.1 KPI43696.1 - 0.15 11.3 5.9 0.28 10.4 5.9 1.4 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3658 PF12395.8 KPI43696.1 - 0.16 11.9 0.5 0.35 10.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function SF3A2 PF16835.5 KPI43697.1 - 1.8e-37 127.6 0.0 2.5e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KPI43697.1 - 2e-05 24.8 0.5 2e-05 24.8 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KPI43697.1 - 0.061 12.9 1.5 0.11 12.1 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Snf7 PF03357.21 KPI43698.1 - 6.6e-11 42.1 3.6 9.2e-11 41.6 3.6 1.2 1 0 0 1 1 1 1 Snf7 Fibrillarin PF01269.17 KPI43699.1 - 2.8e-55 186.9 0.0 7.6e-36 123.3 0.0 2.0 1 1 1 2 2 2 2 Fibrillarin Sugar_tr PF00083.24 KPI43700.1 - 1.3e-96 324.2 25.1 1.6e-96 323.9 25.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43700.1 - 1.3e-13 50.7 46.6 5.6e-11 41.9 34.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe_hyd_lg_C PF02906.14 KPI43702.1 - 9.5e-47 159.7 0.0 2.1e-46 158.6 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain PRAS PF15798.5 KPI43702.1 - 0.068 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 ALS2CR11 PF15729.5 KPI43703.1 - 0.017 14.3 0.7 0.022 13.9 0.1 1.4 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 Arf PF00025.21 KPI43704.1 - 1.7e-28 99.3 0.6 1.7e-15 56.9 0.3 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KPI43704.1 - 0.00027 20.4 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KPI43704.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 KPI43704.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KPI43704.1 - 0.028 13.7 0.1 0.035 13.4 0.1 1.2 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Roc PF08477.13 KPI43704.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Cyclase PF04199.13 KPI43706.1 - 1.2e-08 35.3 0.0 2.7e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase adh_short PF00106.25 KPI43707.1 - 1.4e-20 73.6 0.0 9.5e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43707.1 - 1.9e-12 47.3 0.1 1.7e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI43707.1 - 2.3e-07 30.9 0.1 4e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KPI43707.1 - 0.086 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sas10_Utp3 PF04000.15 KPI43708.1 - 2e-12 47.6 1.9 2e-12 47.6 1.9 2.5 3 0 0 3 3 3 1 Sas10/Utp3/C1D family GRIN_C PF15235.6 KPI43709.1 - 0.78 10.0 3.0 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Fungal_trans PF04082.18 KPI43710.1 - 6.7e-15 54.8 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S11 PF00411.19 KPI43711.1 - 0.00058 20.3 0.0 0.027 14.9 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S11 SPT16 PF08644.11 KPI43712.1 - 7e-56 188.6 0.1 7e-56 188.6 0.1 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KPI43712.1 - 2.2e-49 167.3 2.1 2.7e-49 167.0 0.4 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KPI43712.1 - 3.1e-25 89.1 0.0 5.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KPI43712.1 - 2.3e-12 47.2 0.0 7.7e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like GST_C PF00043.25 KPI43714.1 - 8.9e-13 48.3 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPI43714.1 - 1.3e-08 35.2 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI43714.1 - 5.1e-08 33.2 0.0 8.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI43714.1 - 9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI43714.1 - 2e-06 27.7 0.1 6.6e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI43714.1 - 5.2e-05 23.5 0.0 0.00014 22.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KPI43714.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1744 PF08490.12 KPI43715.1 - 1.8e-147 491.1 0.2 2.7e-147 490.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KPI43715.1 - 4.9e-82 275.8 1.1 3.8e-81 272.9 1.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KPI43715.1 - 6.1e-16 58.2 1.2 1.5e-13 50.3 1.2 3.7 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KPI43715.1 - 3e-07 30.3 0.2 1.1e-06 28.5 0.2 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KPI43715.1 - 0.00023 21.2 0.0 0.00072 19.6 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily Transferase PF02458.15 KPI43716.1 - 2.5e-20 72.6 0.0 1.6e-18 66.6 0.0 2.8 1 1 0 1 1 1 1 Transferase family HEAT PF02985.22 KPI43717.1 - 7e-17 60.1 6.0 0.00043 20.3 0.0 9.3 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 KPI43717.1 - 1.4e-10 41.4 4.6 5.5e-05 23.5 0.1 6.4 2 2 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KPI43717.1 - 2.1e-06 28.1 12.2 9e-05 22.9 0.0 7.3 11 0 0 11 11 11 1 HEAT-like repeat Cnd1 PF12717.7 KPI43717.1 - 1.3e-05 25.3 0.9 0.00042 20.4 0.0 3.7 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KPI43717.1 - 0.00076 19.1 0.1 1.9 8.0 0.0 4.1 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.12 KPI43717.1 - 0.0029 17.3 0.7 0.44 10.2 0.2 3.8 3 1 1 4 4 4 1 NUC173 domain Arm PF00514.23 KPI43717.1 - 0.015 15.4 0.5 4.6 7.4 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ig_J_chain PF15097.6 KPI43717.1 - 0.022 14.6 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin J chain TIP120 PF08623.10 KPI43717.1 - 0.063 13.0 1.6 0.92 9.3 0.0 3.5 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 KPI43717.1 - 0.09 12.7 5.2 15 5.5 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) DUF3431 PF11913.8 KPI43718.1 - 7.1e-20 71.7 0.1 6.4e-19 68.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) IKI3 PF04762.12 KPI43719.1 - 6.8e-100 335.5 0.0 8.1e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 IKI3 family Mod_r PF07200.13 KPI43720.1 - 4.5e-22 78.7 1.4 6.2e-22 78.3 1.4 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 KPI43720.1 - 0.015 15.8 4.1 0.031 14.8 4.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 KPI43720.1 - 0.028 14.7 0.3 0.038 14.2 0.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF755 PF05501.11 KPI43720.1 - 0.1 12.9 3.1 0.18 12.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Fungal_TACC PF12709.7 KPI43720.1 - 0.12 12.9 0.6 0.25 11.8 0.5 1.6 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins TFIIA PF03153.13 KPI43720.1 - 8 6.3 13.9 10 6.0 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amidohydro_2 PF04909.14 KPI43722.1 - 2e-19 70.5 0.0 4e-19 69.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase FAT PF02259.23 KPI43723.1 - 4e-108 361.7 1.1 1.2e-107 360.2 1.1 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KPI43723.1 - 2.6e-72 243.6 0.2 4.5e-72 242.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KPI43723.1 - 1.5e-58 197.3 6.7 3.2e-55 186.4 0.1 6.0 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KPI43723.1 - 2.2e-41 140.3 0.0 2.2e-41 140.3 0.0 3.4 3 1 1 4 4 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 KPI43723.1 - 1.5e-15 56.7 0.1 4.6e-15 55.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KPI43723.1 - 6.8e-12 45.6 13.2 0.00018 21.8 0.0 8.8 8 2 1 10 10 9 2 HEAT repeats HEAT PF02985.22 KPI43723.1 - 1.5e-08 34.2 13.5 0.073 13.4 0.1 10.0 11 0 0 11 11 10 1 HEAT repeat HEAT_EZ PF13513.6 KPI43723.1 - 4.1e-08 33.5 12.8 0.8 10.3 0.0 9.9 9 1 2 11 11 11 2 HEAT-like repeat MMS19_C PF12460.8 KPI43723.1 - 0.0039 16.4 7.6 0.038 13.1 0.3 4.4 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 KPI43723.1 - 0.0048 16.1 0.5 1.9 7.5 0.0 3.3 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 KPI43723.1 - 0.021 14.4 5.4 22 4.5 0.0 5.5 7 0 0 7 7 7 0 CLASP N terminal RTP1_C1 PF10363.9 KPI43723.1 - 0.06 13.5 2.3 15 5.8 0.2 5.4 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 KPI43723.1 - 0.13 12.2 0.0 11 5.8 0.0 3.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UME PF08064.13 KPI43723.1 - 0.62 10.0 10.6 56 3.7 0.0 6.8 7 0 0 7 7 6 0 UME (NUC010) domain OTU PF02338.19 KPI43724.1 - 1.1e-09 38.9 0.0 1.8e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UBX PF00789.20 KPI43724.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 UBX domain ubiquitin PF00240.23 KPI43724.1 - 0.13 12.0 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family DUF2183 PF09949.9 KPI43725.1 - 7.6e-21 74.3 0.1 1.5e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SET PF00856.28 KPI43726.1 - 2.9e-12 47.3 0.0 8.8e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 SET domain ST7 PF04184.12 KPI43726.1 - 0.034 12.6 0.6 0.051 12.1 0.6 1.2 1 0 0 1 1 1 0 ST7 protein Ank_5 PF13857.6 KPI43727.1 - 3.2e-18 65.5 0.0 4.9e-13 49.0 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) VPS9 PF02204.18 KPI43727.1 - 2.2e-17 63.2 0.0 5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KPI43727.1 - 1e-14 54.9 0.0 1.2e-05 25.8 0.0 4.4 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPI43727.1 - 3.2e-08 33.2 0.5 0.37 11.5 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KPI43727.1 - 8e-08 32.7 0.0 0.03 14.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) PX PF00787.24 KPI43727.1 - 0.00026 20.9 0.0 0.00074 19.5 0.0 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.30 KPI43727.1 - 0.0003 21.1 0.0 1.7 9.3 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Fungal_trans_2 PF11951.8 KPI43729.1 - 0.00067 18.6 0.2 0.0013 17.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioredoxin PF00085.20 KPI43730.1 - 1.8e-20 72.8 0.1 2e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KPI43730.1 - 6.3e-07 29.8 0.3 1.3e-06 28.8 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KPI43730.1 - 1.2e-05 25.6 0.0 0.0013 19.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KPI43730.1 - 4e-05 23.1 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KPI43730.1 - 0.00013 21.9 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.11 KPI43730.1 - 0.0002 21.3 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KPI43730.1 - 0.00079 19.3 0.2 0.0019 18.1 0.1 1.5 1 1 1 2 2 2 1 AhpC/TSA family DUF953 PF06110.11 KPI43730.1 - 0.0013 18.3 0.2 0.0065 16.1 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 KPI43730.1 - 0.0017 18.5 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KPI43730.1 - 0.0086 15.8 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KPI43730.1 - 0.017 14.9 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 KPI43730.1 - 0.027 14.7 0.1 0.05 13.8 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 KPI43730.1 - 0.028 14.2 0.2 1.4 8.7 0.2 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 KPI43730.1 - 0.061 13.0 0.2 0.84 9.3 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin CobU PF02283.16 KPI43730.1 - 0.07 12.7 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Phospholip_A2_3 PF09056.11 KPI43731.1 - 1e-33 116.3 0.1 1.2e-33 116.1 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 RRM_1 PF00076.22 KPI43732.1 - 4.9e-14 51.9 0.0 7.5e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 KPI43733.1 - 1.1e-22 80.3 11.2 2.3e-22 79.2 11.2 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) PGM_PMM_I PF02878.16 KPI43734.1 - 7.4e-34 116.4 0.0 1.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KPI43734.1 - 4e-24 85.0 0.0 7.4e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KPI43734.1 - 4.7e-16 59.3 0.0 9.8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KPI43734.1 - 0.0015 18.6 0.1 0.0035 17.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GGACT PF06094.12 KPI43735.1 - 0.00013 22.6 0.0 0.00025 21.6 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like FA_desaturase PF00487.24 KPI43736.1 - 6.2e-20 72.1 14.5 6.2e-20 72.1 14.5 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KPI43736.1 - 8e-17 61.2 0.1 1.9e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Oleosin PF01277.17 KPI43736.1 - 0.21 11.4 1.5 0.63 9.8 1.5 1.8 1 0 0 1 1 1 0 Oleosin Glyco_hydro_72 PF03198.14 KPI43737.1 - 6.2e-81 272.1 0.2 1.4e-80 271.0 0.2 1.5 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KPI43737.1 - 0.069 12.2 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Sod_Cu PF00080.20 KPI43738.1 - 2.6e-11 43.9 0.2 4.1e-11 43.2 0.2 1.4 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SprA-related PF12118.8 KPI43738.1 - 3.9 6.5 7.2 6.3 5.8 7.2 1.3 1 0 0 1 1 1 0 SprA-related family Abhydrolase_6 PF12697.7 KPI43739.1 - 0.0048 17.5 0.0 0.013 16.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LOR PF04525.12 KPI43740.1 - 1.1e-08 34.9 0.2 3.1e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 LURP-one-related PH_6 PF15406.6 KPI43741.1 - 6.6e-29 100.5 3.3 6.6e-29 100.5 3.3 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KPI43741.1 - 6.5e-05 23.4 1.1 0.0012 19.4 0.1 2.8 2 0 0 2 2 2 1 PH domain PH_4 PF15404.6 KPI43741.1 - 6.7 6.5 9.2 1.5 8.6 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PAPS_reduct PF01507.19 KPI43742.1 - 3.4e-42 144.4 0.0 4.5e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FSH1 PF03959.13 KPI43743.1 - 1.3e-54 185.1 0.0 1.5e-52 178.3 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ribosomal_S27e PF01667.17 KPI43743.1 - 6.6e-27 93.0 6.1 1.2e-26 92.2 6.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 Hydrolase_4 PF12146.8 KPI43743.1 - 0.011 15.1 0.1 0.034 13.4 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 KPI43744.1 - 2.3e-39 135.4 0.0 2.9e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43744.1 - 7e-38 130.0 0.0 9.4e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI43744.1 - 8e-09 35.7 0.0 1.1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 KR domain MoaC PF01967.21 KPI43745.1 - 8.8e-38 129.5 0.1 1.7e-37 128.6 0.1 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KPI43745.1 - 6.8e-36 123.0 0.0 5.2e-35 120.2 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KPI43745.1 - 8.1e-28 97.9 0.2 1.5e-27 97.1 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KPI43745.1 - 5.4e-07 30.0 0.0 1.6e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KPI43745.1 - 0.0061 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Chitin_synth_2 PF03142.15 KPI43748.1 - 6.3e-217 721.4 0.8 1.6e-215 716.7 0.8 2.0 1 1 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KPI43748.1 - 5.7e-15 55.0 0.0 2.3e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KPI43748.1 - 5.8e-15 55.2 1.0 3.6e-11 43.1 0.1 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KPI43748.1 - 8.8e-15 55.1 4.1 8.8e-15 55.1 4.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KPI43748.1 - 2.9e-13 50.2 0.0 3e-12 46.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KPI43748.1 - 1.2e-07 30.4 0.0 3.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KPI43748.1 - 3.3e-05 23.4 0.1 0.00073 19.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KPI43748.1 - 0.0011 18.8 0.0 0.25 11.1 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Vps52 PF04129.12 KPI43750.1 - 5.3e-121 404.9 0.0 6.9e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF812 PF05667.11 KPI43750.1 - 0.00047 19.2 0.5 0.00073 18.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 KPI43750.1 - 0.0034 16.3 1.5 0.0059 15.5 1.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec3_C PF09763.9 KPI43750.1 - 0.0057 15.1 0.1 0.0093 14.4 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 THOC7 PF05615.13 KPI43750.1 - 0.01 16.1 3.3 0.018 15.3 2.7 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 SmpA_OmlA PF04355.13 KPI43750.1 - 0.078 12.8 0.2 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 SmpA / OmlA family DUF3909 PF13077.6 KPI43750.1 - 0.078 13.1 0.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) MitMem_reg PF13012.6 KPI43750.1 - 0.23 11.9 1.4 13 6.2 1.4 2.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Nbl1_Borealin_N PF10444.9 KPI43750.1 - 0.25 11.0 2.3 13 5.5 0.3 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal APG6_N PF17675.1 KPI43750.1 - 2.5 8.6 6.2 8.4 6.9 5.5 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 KPI43751.1 - 1.6e-12 47.7 4.1 0.0034 18.2 0.5 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI43751.1 - 0.0047 17.2 0.0 13 6.2 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 KPI43751.1 - 0.11 12.8 0.4 0.47 10.8 0.4 2.1 1 0 0 1 1 1 0 Kelch motif Ureide_permease PF07168.11 KPI43752.1 - 0.017 13.9 3.6 0.026 13.3 3.6 1.2 1 0 0 1 1 1 0 Ureide permease NPR3 PF03666.13 KPI43752.1 - 0.054 12.3 11.2 2.3 6.9 10.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 KPI43752.1 - 0.07 12.9 3.8 0.12 12.1 3.8 1.5 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 KPI43752.1 - 0.098 13.0 17.6 0.15 12.4 17.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 KPI43752.1 - 0.26 9.6 10.2 0.33 9.2 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KPI43752.1 - 0.49 9.1 7.9 0.7 8.6 7.9 1.2 1 0 0 1 1 1 0 Presenilin Apis_Csd PF11671.8 KPI43752.1 - 0.58 10.2 6.3 1 9.4 6.3 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Tim54 PF11711.8 KPI43752.1 - 0.64 8.7 10.8 0.95 8.2 10.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TT_ORF1 PF02956.14 KPI43752.1 - 0.83 8.3 5.4 1.1 7.8 5.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 RPN2_C PF18004.1 KPI43752.1 - 2.4 8.1 18.8 4.4 7.2 18.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_Rpc4 PF05132.14 KPI43752.1 - 2.7 8.4 10.8 6 7.3 10.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 KPI43752.1 - 2.8 7.1 7.4 1.3 8.2 4.8 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter LMBR1 PF04791.16 KPI43752.1 - 6 5.6 6.3 8.4 5.2 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AA_permease PF00324.21 KPI43753.1 - 1.4e-118 396.6 33.7 1.8e-118 396.2 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI43753.1 - 1.4e-26 93.3 36.4 2.3e-26 92.6 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease NUP50 PF08911.11 KPI43754.1 - 0.018 15.7 1.7 4 8.2 0.1 2.7 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) Fungal_trans PF04082.18 KPI43755.1 - 3.8e-13 49.1 0.0 5.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF726 PF05277.12 KPI43756.1 - 1.2e-116 389.4 1.8 1.7e-116 388.9 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DMAP1 PF05499.12 KPI43756.1 - 0.093 12.6 1.2 0.22 11.4 1.2 1.7 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Fungal_trans PF04082.18 KPI43757.1 - 2e-13 50.0 0.2 3e-13 49.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43757.1 - 6e-08 32.7 10.0 1.1e-07 31.8 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KPI43759.1 - 3.6e-33 113.1 6.0 1.7e-05 25.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KPI43759.1 - 7.8e-08 32.1 0.6 2e-07 30.8 0.6 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KPI43759.1 - 1.6e-07 31.5 0.1 0.48 10.7 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI43759.1 - 1.3e-05 24.1 0.4 0.017 13.8 0.0 3.9 3 1 2 5 5 5 1 Nucleoporin Nup120/160 F-box PF00646.33 KPI43759.1 - 1.5e-05 24.7 0.6 2.9e-05 23.8 0.6 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 KPI43759.1 - 0.049 14.1 0.1 52 4.5 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 KPI43759.1 - 0.049 13.6 0.2 6.7 6.8 0.1 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat MCRA PF06100.11 KPI43760.1 - 0.08 11.7 1.8 0.11 11.2 1.8 1.1 1 0 0 1 1 1 0 MCRA family WD40 PF00400.32 KPI43761.1 - 6.6e-36 121.7 14.3 2e-09 37.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI43761.1 - 9.3e-13 48.3 1.9 0.032 14.5 0.1 5.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI43761.1 - 6.7e-08 31.9 0.0 0.65 8.9 0.0 4.2 3 1 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KPI43761.1 - 1.3e-06 27.6 3.2 6.6e-05 22.0 0.1 3.3 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KPI43761.1 - 0.00091 18.1 0.1 0.58 8.8 0.0 3.6 1 1 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.8 KPI43761.1 - 0.0055 15.4 6.3 0.077 11.6 0.1 3.6 2 1 1 4 4 4 1 Nucleoporin Nup120/160 HPS3_N PF14761.6 KPI43761.1 - 0.015 14.8 0.0 0.13 11.7 0.0 2.3 1 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Hira PF07569.11 KPI43761.1 - 0.14 11.8 1.4 0.96 9.1 0.2 2.9 2 1 1 3 3 3 0 TUP1-like enhancer of split PUF PF00806.19 KPI43762.1 - 9.6e-27 91.1 0.0 0.00018 21.0 0.0 6.5 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KPI43762.1 - 1.3e-10 40.9 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KPI43762.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif Efg1 PF10153.9 KPI43763.1 - 1e-21 77.4 2.8 2e-21 76.5 2.8 1.5 1 0 0 1 1 1 1 rRNA-processing protein Efg1 Polysacc_deac_1 PF01522.21 KPI43764.1 - 1.6e-17 63.5 0.0 2.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KPI43764.1 - 9.4e-05 22.2 0.0 0.00017 21.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KPI43764.1 - 0.088 11.1 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Methyltransf_25 PF13649.6 KPI43765.1 - 3.2e-17 63.0 0.0 1.2e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI43765.1 - 1.6e-16 60.6 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI43765.1 - 2.7e-16 60.0 0.0 3.1e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI43765.1 - 4.5e-12 46.6 0.0 7.4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI43765.1 - 6.2e-11 42.3 0.0 9.4e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPI43765.1 - 5.4e-09 35.7 0.0 6.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KPI43765.1 - 7.6e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KPI43765.1 - 2.7e-05 23.7 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 KPI43765.1 - 0.0003 20.0 0.0 0.0015 17.7 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme TehB PF03848.14 KPI43765.1 - 0.00053 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KPI43765.1 - 0.0015 17.6 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CheR PF01739.18 KPI43765.1 - 0.01 15.3 0.0 3.2 7.2 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TPMT PF05724.11 KPI43765.1 - 0.017 14.8 0.0 0.068 12.8 0.0 1.9 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) UPF0146 PF03686.13 KPI43765.1 - 0.044 13.7 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) NNMT_PNMT_TEMT PF01234.17 KPI43765.1 - 0.047 12.9 0.0 0.57 9.3 0.0 2.1 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family POR PF01558.18 KPI43765.1 - 0.062 13.4 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase UDPG_MGDP_dh_N PF03721.14 KPI43765.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MOSC_N PF03476.16 KPI43765.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain PCMT PF01135.19 KPI43765.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 KPI43765.1 - 0.17 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KPI43765.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ribosomal_L1 PF00687.21 KPI43766.1 - 2.6e-41 141.6 0.6 3e-40 138.1 0.6 1.9 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family COesterase PF00135.28 KPI43767.1 - 6.8e-61 206.7 0.0 4.8e-59 200.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI43767.1 - 2.3e-06 27.7 0.3 0.029 14.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PRIMA1 PF16101.5 KPI43768.1 - 0.043 13.8 5.8 0.1 12.7 5.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LEA_6 PF10714.9 KPI43768.1 - 1.2 9.2 5.0 0.16 12.0 0.5 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Podoplanin PF05808.11 KPI43768.1 - 2.1 8.4 10.9 2.6 8.1 1.1 2.3 2 0 0 2 2 2 0 Podoplanin SOG2 PF10428.9 KPI43768.1 - 3 6.9 12.7 3.2 6.8 12.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPATA3 PF15662.5 KPI43768.1 - 3.9 8.1 20.9 4.2 8.0 17.7 2.3 2 1 0 2 2 2 0 Spermatogenesis-associated protein 3 family DAO PF01266.24 KPI43769.1 - 1.1e-30 107.4 2.7 1.2e-30 107.3 2.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI43769.1 - 0.00029 20.0 2.1 0.00046 19.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI43769.1 - 0.00086 19.5 0.1 0.00086 19.5 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI43769.1 - 0.0047 16.2 0.7 0.0092 15.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KPI43769.1 - 0.0086 15.3 0.1 0.0086 15.3 0.1 2.9 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KPI43769.1 - 0.016 14.7 0.1 0.44 10.0 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KPI43769.1 - 0.071 12.3 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KPI43769.1 - 0.13 11.1 0.2 0.69 8.7 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KPI43769.1 - 0.13 10.9 0.8 0.19 10.4 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 KPI43769.1 - 0.14 12.5 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PhyH PF05721.13 KPI43770.1 - 2.6e-20 73.6 0.1 3.6e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KPI43770.1 - 0.029 14.8 0.1 0.82 10.1 0.0 2.4 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase Abhydrolase_6 PF12697.7 KPI43771.1 - 1.4e-08 35.6 0.3 2.2e-08 35.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI43771.1 - 0.0015 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI43771.1 - 0.028 14.1 0.5 0.14 11.8 0.5 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI43771.1 - 0.036 13.5 0.0 7.7 5.9 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family TRI12 PF06609.13 KPI43772.1 - 1.5e-23 83.1 29.4 2.6e-23 82.3 29.5 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI43772.1 - 2.1e-16 59.8 60.9 3.7e-16 59.0 55.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily AnmK PF03702.14 KPI43773.1 - 4.4e-09 35.9 0.0 4.8e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Glyco_hydro_65N PF03636.15 KPI43775.1 - 2.4e-35 122.2 0.0 3.8e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KPI43775.1 - 2.7e-24 85.8 6.7 1.9e-20 73.1 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KPI43775.1 - 0.057 13.3 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain LigB PF02900.18 KPI43776.1 - 6.7e-14 51.6 0.0 8.4e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_16 PF00722.21 KPI43777.1 - 0.00014 21.4 0.0 0.00036 20.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 GRP PF07172.11 KPI43777.1 - 1.4 9.6 13.9 0.56 10.9 6.3 2.4 2 0 0 2 2 2 0 Glycine rich protein family Acyl-CoA_dh_1 PF00441.24 KPI43779.1 - 9.1e-15 55.2 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KPI43779.1 - 4.1e-14 52.8 0.0 7.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI43779.1 - 7.5e-12 45.3 0.0 2.6e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cpn60_TCP1 PF00118.24 KPI43780.1 - 5.6e-164 546.4 0.9 6.3e-164 546.2 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KPI43780.1 - 0.072 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Methyltransf_2 PF00891.18 KPI43781.1 - 6e-13 48.6 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KPI43781.1 - 0.0068 16.4 0.1 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain FMO-like PF00743.19 KPI43782.1 - 4.7e-15 55.0 0.1 1.4e-13 50.1 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI43782.1 - 6.2e-08 32.8 1.1 1.3e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI43782.1 - 0.00013 21.2 0.1 0.00052 19.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KPI43782.1 - 0.0023 17.2 0.0 2.3 7.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI43782.1 - 0.055 12.7 0.0 2 7.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI43783.1 - 1.4e-43 149.5 0.0 1.3e-42 146.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain CHORD PF04968.12 KPI43784.1 - 1.9e-42 143.8 13.8 3.2e-23 82.2 6.9 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KPI43784.1 - 4e-11 43.8 0.1 6.3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 CS domain K_channel_TID PF07941.11 KPI43784.1 - 0.66 10.5 5.7 5 7.6 0.2 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Sugar_tr PF00083.24 KPI43785.1 - 6.1e-83 279.2 16.9 7.8e-83 278.8 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43785.1 - 6.4e-09 35.2 40.3 9e-06 24.8 12.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 KPI43786.1 - 2.8e-06 27.5 8.8 9.9e-06 25.7 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI43786.1 - 1.4e-05 25.3 6.8 3.8e-05 23.9 0.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KPI43786.1 - 0.00017 21.5 0.7 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 KPI43786.1 - 0.0002 21.9 5.9 0.29 11.8 0.1 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KPI43786.1 - 0.00027 21.5 2.5 0.0068 17.2 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KPI43786.1 - 0.11 12.9 0.2 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KPI43786.1 - 0.15 11.8 0.1 0.67 9.8 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KPI43786.1 - 0.23 11.8 2.2 5.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 KPI43786.1 - 0.26 11.2 5.0 6.6 6.6 0.8 2.2 1 1 1 2 2 2 0 Seven in absentia protein family zf-H2C2_5 PF13909.6 KPI43786.1 - 0.42 10.4 5.7 0.78 9.6 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zap1_zf2 PF18217.1 KPI43786.1 - 2.5 8.2 9.5 2.6 8.1 4.6 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 adh_short_C2 PF13561.6 KPI43787.1 - 1.7e-56 191.4 0.1 2e-56 191.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43787.1 - 8.8e-48 162.3 0.0 1.1e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI43787.1 - 1.4e-10 41.4 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI43787.1 - 0.0028 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KPI43787.1 - 0.0074 16.4 0.6 0.013 15.6 0.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 KPI43787.1 - 0.0098 15.2 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 KPI43787.1 - 0.028 13.4 0.0 0.058 12.4 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPI43787.1 - 0.034 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 KPI43787.1 - 0.042 14.3 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KPI43787.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Urocanase PF01175.18 KPI43787.1 - 0.12 12.0 0.4 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Fungal_trans_2 PF11951.8 KPI43788.1 - 1.9e-16 59.8 1.8 4.1e-15 55.5 0.6 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43788.1 - 0.0012 18.9 5.6 0.0021 18.2 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC1 PF07064.13 KPI43789.1 - 8.5e-38 130.2 0.2 1.3e-37 129.6 0.2 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KPI43789.1 - 0.03 14.6 0.1 0.39 11.0 0.0 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 KPI43790.1 - 9.7e-23 80.6 7.2 3.5e-22 78.7 7.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain N2227 PF07942.12 KPI43791.1 - 5.7e-35 120.8 0.0 8.8e-35 120.2 0.0 1.3 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KPI43791.1 - 0.023 14.5 0.0 0.03 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPI43791.1 - 0.075 13.7 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KPI43792.1 - 4e-22 78.5 0.0 8.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 KPI43793.1 - 5.9e-51 173.6 0.0 8.3e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI43793.1 - 1.1e-32 113.5 0.0 2.1e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI43793.1 - 6e-05 22.3 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KPI43793.1 - 6.5e-05 22.1 0.1 0.00013 21.2 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPI43793.1 - 9.7e-05 22.5 0.2 0.00027 21.1 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI43793.1 - 0.0019 17.8 0.2 0.0093 15.6 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI43793.1 - 0.013 14.8 0.0 0.027 13.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KPI43793.1 - 0.033 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mit_ribos_Mrp51 PF11709.8 KPI43794.1 - 7.5e-78 262.7 0.5 2.9e-75 254.1 0.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 KPI43795.1 - 2.9e-60 201.5 0.6 3.5e-60 201.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal S17 GUCT PF08152.12 KPI43795.1 - 0.099 12.9 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 GUCT (NUC152) domain Cyclin_N PF00134.23 KPI43796.1 - 1.4e-14 53.9 0.2 2.5e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPI43796.1 - 0.017 15.2 0.5 0.94 9.6 0.0 2.6 2 1 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.19 KPI43796.1 - 0.03 14.4 1.5 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KPI43796.1 - 0.068 13.6 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain Totivirus_coat PF05518.11 KPI43796.1 - 8.5 4.3 11.2 14 3.6 11.2 1.3 1 0 0 1 1 1 0 Totivirus coat protein Zn_clus PF00172.18 KPI43797.1 - 0.027 14.6 9.3 0.057 13.5 9.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lin-8 PF03353.15 KPI43797.1 - 3.6 7.1 12.2 0.74 9.3 6.9 2.4 2 1 0 2 2 2 0 Ras-mediated vulval-induction antagonist Octopine_DH PF02317.17 KPI43798.1 - 0.074 13.1 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain V-SNARE_C PF12352.8 KPI43799.1 - 1e-14 54.5 0.2 1e-14 54.5 0.2 2.7 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus FlgT_M PF16539.5 KPI43799.1 - 0.0092 16.1 1.8 0.0092 16.1 1.8 1.6 1 1 1 2 2 2 1 Flagellar assembly protein T, middle domain Surfac_D-trimer PF09006.11 KPI43799.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Rab3-GTPase_cat PF13890.6 KPI43799.1 - 0.055 13.1 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF1822 PF08852.11 KPI43799.1 - 0.14 11.2 4.3 0.18 10.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) STAT_alpha PF01017.20 KPI43799.1 - 0.25 11.2 5.9 0.67 9.8 5.9 1.8 1 1 0 1 1 1 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.11 KPI43799.1 - 0.29 11.7 8.8 0.42 11.2 7.4 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DAHP_synth_1 PF00793.20 KPI43800.1 - 2.9e-87 292.0 0.0 3.7e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2313 PF10076.9 KPI43800.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) Fungal_trans PF04082.18 KPI43801.1 - 1.2e-15 57.3 0.0 5.1e-09 35.5 0.0 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43801.1 - 3.6e-06 27.0 8.1 5.7e-06 26.4 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PepX_C PF08530.10 KPI43802.1 - 4.2e-42 144.6 0.3 6.3e-42 144.0 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KPI43802.1 - 6.4e-39 134.2 0.4 9.3e-39 133.6 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF3984 PF13136.6 KPI43803.1 - 1.3e-46 159.5 1.6 2.5e-46 158.6 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Ecm33 PF12454.8 KPI43804.1 - 9.5e-07 28.9 0.4 2.9e-06 27.3 0.4 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KPI43804.1 - 1.7e-05 24.9 2.9 0.11 12.6 0.0 3.6 2 1 1 3 3 3 3 Receptor L domain LRR_5 PF13306.6 KPI43804.1 - 0.061 13.3 0.9 0.3 11.0 0.2 2.4 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KPI43804.1 - 0.096 13.1 11.0 11 6.6 0.6 5.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) NINJA_B PF16136.5 KPI43804.1 - 2.3 8.6 4.0 4.8 7.6 4.0 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal MAGE PF01454.19 KPI43805.1 - 7e-58 195.8 0.0 1.1e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 MAGE family RQC PF09382.10 KPI43805.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 RQC domain DUF1180 PF06679.12 KPI43805.1 - 6.1 7.2 7.3 1.2 9.6 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) BTB PF00651.31 KPI43806.1 - 1.2e-11 44.8 0.4 8.7e-11 42.0 0.2 2.3 2 1 0 2 2 2 1 BTB/POZ domain RTP PF02334.16 KPI43806.1 - 0.051 14.2 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Replication terminator protein Golgin_A5 PF09787.9 KPI43807.1 - 0.0002 20.9 17.7 0.0002 20.9 17.7 2.3 2 0 0 2 2 2 1 Golgin subfamily A member 5 Sec8_exocyst PF04048.14 KPI43807.1 - 0.46 10.4 4.6 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain CENP-F_leu_zip PF10473.9 KPI43807.1 - 2.8 7.9 22.6 0.37 10.8 17.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.16 KPI43807.1 - 5.7 5.7 4.9 9 5.1 4.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein YEATS PF03366.16 KPI43808.1 - 1.4e-10 41.0 1.1 3.1e-10 39.9 1.1 1.6 1 0 0 1 1 1 1 YEATS family zf-C3HC4_4 PF15227.6 KPI43808.1 - 3.7e-07 30.2 2.5 3.7e-07 30.2 2.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KPI43808.1 - 1.7e-06 27.9 1.8 1.7e-06 27.9 1.8 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI43808.1 - 3.3e-06 26.8 4.2 3.3e-06 26.8 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI43808.1 - 5.8e-06 26.1 6.9 4.3e-05 23.3 2.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI43808.1 - 7.1e-06 25.8 5.9 3.1e-05 23.8 5.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI43808.1 - 2.1e-05 24.7 8.8 0.00012 22.4 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPI43808.1 - 0.011 15.7 8.9 0.091 12.7 9.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain GAGA PF09237.11 KPI43808.1 - 0.025 14.4 2.5 0.65 9.9 0.2 2.5 2 0 0 2 2 2 0 GAGA factor zf-RING_10 PF16685.5 KPI43808.1 - 0.22 11.7 5.5 0.18 12.0 2.5 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KPI43808.1 - 0.29 11.0 11.2 10 6.1 0.1 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 RecR PF02132.15 KPI43808.1 - 0.84 9.3 3.2 5.2 6.7 0.7 2.5 2 0 0 2 2 2 0 RecR protein zf-RING_4 PF14570.6 KPI43808.1 - 7 6.5 8.0 35 4.3 5.4 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Acyl-CoA_dh_M PF02770.19 KPI43809.1 - 2.3e-22 79.0 0.1 4e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KPI43809.1 - 3.5e-21 76.0 0.9 6.4e-21 75.1 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI43809.1 - 3.1e-15 56.8 1.9 1.6e-14 54.5 0.0 2.8 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPI43809.1 - 0.00072 19.8 0.2 0.0012 19.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CrtC PF07143.11 KPI43809.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain Methyltransf_8 PF05148.15 KPI43810.1 - 1e-56 192.2 0.0 3.4e-54 184.0 0.0 2.9 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KPI43810.1 - 6.1e-06 26.8 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI43810.1 - 0.00089 19.9 0.0 0.016 15.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPI43810.1 - 0.032 14.2 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF4294 PF14127.6 KPI43811.1 - 0.1 12.5 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DUF4551 PF15087.6 KPI43811.1 - 0.56 9.0 2.1 0.93 8.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) UBA_4 PF14555.6 KPI43811.1 - 1.7 8.5 6.5 0.18 11.7 0.3 2.5 3 0 0 3 3 3 0 UBA-like domain GST_C_3 PF14497.6 KPI43812.1 - 1.6e-32 111.6 0.2 2.8e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI43812.1 - 2.4e-06 27.7 0.0 3.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI43812.1 - 2.7e-05 24.1 0.0 5.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain A-2_8-polyST PF07388.11 KPI43812.1 - 0.14 10.7 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) DUF2235 PF09994.9 KPI43813.1 - 1.8e-70 237.6 0.0 1.3e-69 234.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ACBP PF00887.19 KPI43815.1 - 2.1e-19 69.5 0.4 2.9e-19 69.0 0.4 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein COesterase PF00135.28 KPI43816.1 - 9.1e-92 308.5 0.0 1.3e-91 308.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI43816.1 - 0.00035 20.5 0.1 0.0019 18.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI43816.1 - 0.06 12.8 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Na_Ca_ex PF01699.24 KPI43817.1 - 7.4e-16 58.5 11.8 1.1e-14 54.6 7.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RhodobacterPufX PF11511.8 KPI43817.1 - 0.21 11.2 0.4 5.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Fungal_TACC PF12709.7 KPI43818.1 - 3.2e-08 33.9 3.5 3.2e-08 33.9 3.5 4.1 3 1 1 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF745 PF05335.13 KPI43818.1 - 0.0053 16.5 7.1 0.0053 16.5 7.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF745) DUF4407 PF14362.6 KPI43818.1 - 0.031 13.6 24.2 0.044 13.1 6.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CT_C_D PF02682.16 KPI43818.1 - 0.037 13.7 0.3 0.17 11.6 0.0 2.1 1 1 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D DUF496 PF04363.12 KPI43818.1 - 0.043 13.9 2.8 0.14 12.2 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF496) ERM PF00769.19 KPI43818.1 - 1.8 8.3 48.9 5.5 6.7 14.4 3.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nramp PF01566.18 KPI43819.1 - 2.9e-72 243.6 13.8 5.6e-65 219.6 11.3 2.7 1 1 1 2 2 2 2 Natural resistance-associated macrophage protein Ribosomal_S21 PF01165.20 KPI43820.1 - 6.2e-09 35.4 3.6 1e-08 34.7 3.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Abhydrolase_1 PF00561.20 KPI43821.1 - 4.6e-12 46.1 0.0 1.4e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI43821.1 - 1e-06 29.6 0.0 1.3e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI43821.1 - 0.061 12.8 0.0 9.6 5.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aminotran_4 PF01063.19 KPI43822.1 - 6.7e-32 111.2 0.0 7.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Complex1_LYR PF05347.15 KPI43825.1 - 3.3e-20 71.9 1.9 4.2e-20 71.5 1.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPI43825.1 - 8.5e-07 29.6 0.3 9.3e-07 29.5 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Glutaredoxin2_C PF04399.13 KPI43825.1 - 0.029 14.2 0.1 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain OPT PF03169.15 KPI43826.1 - 6e-113 378.6 6.7 7.3e-113 378.3 6.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FERM_M PF00373.18 KPI43826.1 - 0.12 12.8 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 FERM central domain DUF3054 PF11255.8 KPI43826.1 - 9.4 6.8 11.9 1.2 9.7 2.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3054) Sugar_tr PF00083.24 KPI43827.1 - 3e-12 46.2 0.3 3.3e-12 46.0 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Thiolase_C PF02803.18 KPI43829.1 - 1.3e-12 47.4 1.1 1.7e-12 47.1 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KPI43829.1 - 2.6e-09 36.8 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KPI43829.1 - 2.5e-05 24.0 0.3 6.2e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KPI43829.1 - 0.00016 21.3 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KPI43829.1 - 0.027 13.2 0.1 0.045 12.5 0.1 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) FMO-like PF00743.19 KPI43830.1 - 1.9e-06 26.6 0.0 2.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI43830.1 - 7.3e-06 25.4 0.1 6.6e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI43830.1 - 0.0013 18.9 0.0 0.0047 17.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain tRNA_int_endo PF01974.17 KPI43830.1 - 0.021 14.9 0.3 0.04 14.0 0.3 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain NAD_binding_9 PF13454.6 KPI43830.1 - 0.034 14.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI43830.1 - 0.041 13.1 0.0 8.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI43830.1 - 0.2 11.7 0.1 0.54 10.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KPI43831.1 - 7.8e-14 51.8 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI43831.1 - 2e-06 27.6 0.5 6.6e-06 26.0 0.5 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Inhibitor_I78 PF11720.8 KPI43832.1 - 7.2e-06 26.0 0.0 8.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KPI43832.1 - 0.0067 17.1 0.0 0.0095 16.6 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Forkhead PF00250.18 KPI43833.1 - 5.3e-13 49.0 0.9 1.1e-12 48.0 0.9 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KPI43833.1 - 2.5e-06 27.7 0.1 5.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 FHA domain ATP-synt_F PF01990.17 KPI43835.1 - 8.8e-34 115.7 0.1 1e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF202 PF02656.15 KPI43836.1 - 2.4e-10 40.7 1.6 3e-10 40.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Rhodanese PF00581.20 KPI43837.1 - 2.1e-08 34.6 0.1 5.6e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 Rhodanese-like domain Cid2 PF09774.9 KPI43838.1 - 3e-46 157.8 0.0 3.8e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 MmgE_PrpD PF03972.14 KPI43839.1 - 4.5e-52 177.1 5.2 5.6e-52 176.8 5.2 1.1 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.16 KPI43840.1 - 4.5e-51 173.8 21.6 4.5e-51 173.8 21.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI43840.1 - 1.4e-11 44.0 5.1 1.4e-11 44.0 5.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KPI43840.1 - 0.13 10.5 5.1 0.099 10.9 0.4 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4179 PF13786.6 KPI43840.1 - 0.95 10.0 2.7 70 4.0 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Adeno_E3_CR2 PF02439.15 KPI43841.1 - 0.0056 16.4 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Pan3_PK PF18101.1 KPI43842.1 - 2e-64 215.7 0.1 3.3e-64 215.0 0.1 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KPI43842.1 - 2.1e-05 24.0 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43842.1 - 0.0048 16.2 0.1 0.0078 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 KPI43844.1 - 8.6e-26 90.7 34.0 8.6e-26 90.7 34.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KPI43844.1 - 0.0019 16.6 11.0 0.011 14.1 0.2 3.4 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KPI43845.1 - 0.00053 18.9 0.1 0.0008 18.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.23 KPI43846.1 - 3.8e-63 213.3 1.0 8.9e-63 212.1 1.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI43846.1 - 5.1e-20 71.9 0.0 5e-19 68.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI43846.1 - 3.9e-10 40.0 0.0 1.3e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI43846.1 - 8.1e-07 29.0 0.1 8.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KPI43846.1 - 0.066 12.8 0.6 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 DEAD_2 ANAPC4 PF12896.7 KPI43848.1 - 3.7e-54 183.3 0.2 5.8e-54 182.7 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KPI43848.1 - 7.5e-11 42.2 0.0 2.5e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF957 PF06117.11 KPI43848.1 - 0.097 12.3 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) GYD PF08734.11 KPI43848.1 - 0.12 12.3 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 GYD domain HpaP PF09483.10 KPI43848.1 - 0.2 11.9 1.8 1.5 9.1 0.6 2.4 2 0 0 2 2 2 0 Type III secretion protein (HpaP) TFIID_20kDa PF03847.13 KPI43850.1 - 3e-18 66.1 0.0 5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2935 PF11155.8 KPI43850.1 - 2.2 8.6 8.0 2.8 8.3 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Herpes_US9 PF06072.11 KPI43851.1 - 0.22 11.4 0.2 0.45 10.4 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2749 PF10907.8 KPI43851.1 - 0.7 10.1 7.4 8 6.7 1.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) Pilin_N PF07790.11 KPI43851.1 - 1.8 9.5 7.5 0.44 11.5 3.4 2.1 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal ATP-sulfurylase PF01747.17 KPI43853.1 - 5.2e-86 287.5 0.0 7.2e-86 287.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KPI43853.1 - 1.4e-55 187.5 0.1 2.3e-55 186.8 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KPI43853.1 - 6.3e-51 172.2 0.0 1e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Surp PF01805.20 KPI43854.1 - 2.3e-12 46.7 0.0 4.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Surp module DUF3767 PF12597.8 KPI43855.1 - 1.6e-18 66.3 0.2 2.5e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 KPI43855.1 - 0.12 11.9 2.2 0.17 11.4 2.2 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT CLN3 PF02487.17 KPI43855.1 - 0.13 11.3 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 CLN3 protein FAM165 PF14981.6 KPI43855.1 - 0.14 12.0 1.7 0.26 11.1 1.3 1.6 1 1 0 1 1 1 0 FAM165 family HET PF06985.11 KPI43856.1 - 2e-26 93.1 0.1 5.5e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pro-rich_19 PF15455.6 KPI43856.1 - 0.36 9.9 1.4 0.62 9.1 1.4 1.3 1 0 0 1 1 1 0 Proline-rich 19 Ferritin_2 PF13668.6 KPI43857.1 - 4.8e-19 68.9 0.1 1.6e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 Ferritin-like domain Ras PF00071.22 KPI43858.1 - 1.9e-36 125.1 0.0 6.2e-36 123.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPI43858.1 - 4.4e-30 104.4 0.0 6.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI43858.1 - 6.5e-12 45.3 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KPI43858.1 - 1.7e-06 28.0 0.0 4.6e-06 26.7 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KPI43858.1 - 7.9e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KPI43858.1 - 0.0001 22.7 0.0 0.00018 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KPI43858.1 - 0.0021 18.0 0.3 0.0086 16.0 0.2 2.1 2 1 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 KPI43858.1 - 0.015 14.5 0.1 0.061 12.5 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KPI43858.1 - 0.029 14.4 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 KPI43858.1 - 0.035 14.4 0.1 0.19 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPI43858.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPI43858.1 - 0.087 13.3 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KPI43858.1 - 0.099 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain dNK PF01712.19 KPI43858.1 - 0.19 11.6 0.0 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase SRPRB PF09439.10 KPI43858.1 - 0.22 10.9 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Vault_4 PF17796.1 KPI43860.1 - 0.14 12.2 0.4 0.41 10.8 0.2 1.8 2 0 0 2 2 2 0 Major Vault Protein repeat domain ATP-synt_10 PF05176.14 KPI43861.1 - 2e-59 200.9 0.0 2.8e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein F-box-like PF12937.7 KPI43862.1 - 7.1e-06 25.8 0.1 2.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KPI43862.1 - 0.14 12.1 0.3 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 F-box Zn_clus PF00172.18 KPI43863.1 - 1.2e-06 28.5 6.3 2.3e-06 27.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HD PF01966.22 KPI43864.1 - 2.6e-06 27.6 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 HD domain Lactamase_B PF00753.27 KPI43865.1 - 7.7e-11 42.4 4.0 1.6e-10 41.3 4.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KPI43865.1 - 1.6e-06 27.7 0.5 2.7e-06 27.1 0.5 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain bZIP_1 PF00170.21 KPI43866.1 - 3.1e-10 40.0 10.0 9.5e-10 38.4 10.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor ZapB PF06005.12 KPI43866.1 - 0.00021 21.7 1.3 0.00021 21.7 1.3 2.9 3 0 0 3 3 3 1 Cell division protein ZapB bZIP_2 PF07716.15 KPI43866.1 - 0.0028 17.7 11.4 0.0028 17.7 11.4 2.6 2 1 0 2 2 2 1 Basic region leucine zipper PilO PF04350.13 KPI43866.1 - 0.042 14.0 0.7 0.042 14.0 0.7 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilO FAM193_C PF15914.5 KPI43866.1 - 1.3 8.9 3.7 0.61 9.9 0.5 2.1 2 0 0 2 2 2 0 FAM193 family C-terminal Chibby PF14645.6 KPI43866.1 - 1.3 9.4 6.8 0.11 12.9 1.2 2.1 2 0 0 2 2 2 0 Chibby family YabA PF06156.13 KPI43866.1 - 2.5 8.8 4.8 0.61 10.8 0.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 KPI43866.1 - 2.6 8.5 4.2 0.64 10.5 0.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) His_Phos_2 PF00328.22 KPI43867.1 - 8.3e-15 55.0 0.0 6.9e-13 48.7 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2076 PF09849.9 KPI43867.1 - 0.046 13.8 2.8 0.072 13.1 2.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MFS_1 PF07690.16 KPI43868.1 - 1.1e-33 116.6 28.4 1.1e-33 116.6 28.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.12 KPI43868.1 - 0.0095 15.9 1.1 0.04 13.9 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF485 PGPGW PF09656.10 KPI43868.1 - 0.81 9.3 7.0 4.4 6.9 2.7 3.1 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) 2-Hacid_dh_C PF02826.19 KPI43869.1 - 4.4e-39 133.7 0.0 7.6e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI43869.1 - 5.7e-12 45.4 0.0 8.3e-12 44.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Sacchrp_dh_NADP PF03435.18 KPI43869.1 - 0.0029 17.9 1.8 0.035 14.4 0.1 2.9 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KPI43869.1 - 0.004 17.7 0.4 0.19 12.4 0.1 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent HSP70 PF00012.20 KPI43870.1 - 2e-11 42.8 0.5 7e-10 37.7 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KPI43870.1 - 0.066 12.0 0.1 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein AAA_23 PF13476.6 KPI43871.1 - 0.16 12.4 5.5 0.22 12.0 5.5 1.3 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KPI43871.1 - 2.3 7.5 10.1 3.4 6.9 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 KPI43871.1 - 6.3 4.9 11.0 8.8 4.4 11.0 1.1 1 0 0 1 1 1 0 Hsp70 protein RR_TM4-6 PF06459.12 KPI43871.1 - 8.8 6.1 9.6 14 5.4 9.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Proteasome PF00227.26 KPI43874.1 - 2.2e-55 187.1 0.0 2.8e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KPI43874.1 - 1.6e-12 46.8 0.2 3.6e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAA_hydrolase PF01557.18 KPI43875.1 - 2.5e-65 220.2 0.0 3.2e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Amidase PF01425.21 KPI43877.1 - 1.4e-86 291.2 0.0 1.7e-86 290.9 0.0 1.1 1 0 0 1 1 1 1 Amidase HIT PF01230.23 KPI43880.1 - 2e-24 86.1 0.8 3.3e-24 85.5 0.8 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KPI43880.1 - 0.00025 21.5 0.2 0.00038 20.9 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KPI43880.1 - 0.0025 17.7 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 KPI43880.1 - 0.0045 16.7 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain PLDc_2 PF13091.6 KPI43881.1 - 3e-25 88.6 0.1 1.3e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KPI43881.1 - 4.9e-05 23.3 0.1 0.09 13.0 0.0 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KPI43881.1 - 0.0076 15.4 0.1 0.87 8.7 0.0 2.4 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB MFS_1 PF07690.16 KPI43882.1 - 7.8e-25 87.5 57.7 5.5e-20 71.6 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Asn_synthase PF00733.21 KPI43883.1 - 7.3e-16 58.8 0.2 1.6e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase SLD3 PF08639.10 KPI43884.1 - 1.8e-115 386.8 19.1 3.2e-115 385.9 19.1 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 adh_short PF00106.25 KPI43885.1 - 5.4e-25 88.0 0.1 8.6e-20 71.0 0.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI43885.1 - 3.5e-16 59.5 0.4 2.1e-12 47.1 0.9 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI43885.1 - 8.9e-07 29.0 0.3 1.6e-06 28.2 0.1 1.5 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KPI43885.1 - 0.00037 20.0 0.1 0.0011 18.4 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI43885.1 - 0.004 16.7 0.3 0.009 15.5 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI43885.1 - 0.0041 16.3 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 KPI43885.1 - 0.017 14.9 0.1 0.049 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1955 PF09205.10 KPI43885.1 - 0.023 14.4 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) KH_6 PF15985.5 KPI43887.1 - 1.2e-15 57.5 0.6 2.3e-15 56.6 0.6 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KPI43887.1 - 0.00024 21.0 2.4 0.00061 19.7 2.4 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain DUF4085 PF13315.6 KPI43887.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) PepSY PF03413.19 KPI43887.1 - 0.17 12.4 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Fungal_trans PF04082.18 KPI43888.1 - 3.5e-21 75.4 0.6 6.2e-21 74.6 0.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43888.1 - 3.8e-09 36.5 10.0 6.8e-09 35.7 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KPI43889.1 - 2.4e-24 85.9 55.9 4.2e-23 81.8 50.7 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI43889.1 - 7.2e-21 74.2 26.3 9.4e-21 73.9 26.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UIM PF02809.20 KPI43890.1 - 0.0046 16.8 3.6 0.018 14.9 3.6 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-Mss51 PF13824.6 KPI43891.1 - 1.1e-27 95.8 9.9 1.3e-27 95.6 8.5 1.9 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KPI43891.1 - 0.00031 20.7 1.1 0.00072 19.6 1.1 1.6 1 0 0 1 1 1 1 MYND finger SMC_Nse1 PF07574.13 KPI43892.1 - 8.3e-53 179.2 0.7 2.2e-52 177.8 0.7 1.7 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KPI43892.1 - 8.6e-14 51.6 10.0 1.3e-13 51.0 10.0 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KPI43892.1 - 0.016 15.5 10.2 0.027 14.8 10.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.6 KPI43892.1 - 0.016 15.3 4.3 0.018 15.2 2.8 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KPI43892.1 - 0.03 14.4 2.4 0.05 13.6 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 KPI43892.1 - 0.086 13.1 7.1 0.32 11.3 7.1 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain Baculo_IE-1 PF05290.11 KPI43892.1 - 0.095 12.6 1.1 0.18 11.8 1.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KPI43892.1 - 0.1 12.9 6.5 0.24 11.7 6.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain MSP7_C PF12948.7 KPI43892.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain C1_2 PF03107.16 KPI43892.1 - 0.57 10.6 5.1 0.46 10.8 2.1 2.1 2 0 0 2 2 2 0 C1 domain Zn_ribbon_17 PF17120.5 KPI43892.1 - 0.78 9.4 5.9 1.3 8.7 5.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KPI43892.1 - 3.5 7.5 8.9 6 6.8 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KPI43892.1 - 6.9 6.6 8.0 19 5.1 7.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KPI43892.1 - 7.4 6.5 9.8 15 5.5 9.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cut8 PF08559.10 KPI43893.1 - 1.7e-70 237.4 0.0 2.5e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein CN_hydrolase PF00795.22 KPI43895.1 - 7.3e-42 143.5 0.0 8.5e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase EHN PF06441.12 KPI43896.1 - 2.3e-31 108.3 0.0 3.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI43896.1 - 3e-15 56.6 0.0 4.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI43896.1 - 0.002 18.8 0.0 0.0034 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FmdE PF02663.14 KPI43897.1 - 0.13 12.3 0.6 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon RTA1 PF04479.13 KPI43898.1 - 6.9e-48 163.0 4.2 9.1e-48 162.6 4.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Pkinase PF00069.25 KPI43899.1 - 2.4e-18 66.4 0.0 4.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43899.1 - 5.4e-09 35.7 0.0 3.1e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KPI43900.1 - 2.5e-22 79.0 0.1 2.7e-22 78.9 0.1 1.0 1 0 0 1 1 1 1 PX domain MoaE PF02391.17 KPI43901.1 - 8.8e-34 116.2 0.0 1.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 MoaE protein DUF4632 PF15451.6 KPI43901.1 - 0.048 13.7 0.3 0.13 12.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) FoP_duplication PF13865.6 KPI43901.1 - 0.073 13.6 1.5 0.14 12.7 1.5 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FCH PF00611.23 KPI43902.1 - 3.3e-16 59.3 0.0 7.3e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KPI43902.1 - 1.8e-10 40.2 0.0 4.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KPI43902.1 - 2.4e-10 40.0 0.1 3.1e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.6 KPI43902.1 - 6.2e-10 38.8 0.1 1.4e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain ANAPC_CDC26 PF10471.9 KPI43902.1 - 0.24 12.2 4.8 0.23 12.3 0.2 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 CxC7 PF18866.1 KPI43903.1 - 0.14 12.4 0.3 0.29 11.3 0.3 1.5 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases DUF3474 PF11960.8 KPI43903.1 - 0.96 9.6 3.5 0.45 10.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Vps39_2 PF10367.9 KPI43904.1 - 1.1e-08 35.5 0.0 3.9e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KPI43904.1 - 0.0041 17.4 0.1 0.12 12.7 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.14 KPI43904.1 - 0.31 11.8 1.9 5.1 8.0 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 KPI43906.1 - 0.0069 15.7 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cyto_heme_lyase PF01265.17 KPI43907.1 - 2.4e-14 53.6 10.9 2.4e-13 50.4 10.9 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase HSP70 PF00012.20 KPI43908.1 - 1.5e-51 175.4 13.1 2.6e-49 168.0 4.4 3.2 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KPI43908.1 - 0.00053 18.9 0.2 0.0012 17.7 0.2 1.6 1 0 0 1 1 1 1 MreB/Mbl protein Poly_export PF02563.16 KPI43908.1 - 0.12 12.6 0.0 0.42 10.9 0.0 2.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Rad51 PF08423.11 KPI43909.1 - 3e-129 429.7 0.0 3.6e-129 429.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KPI43909.1 - 1.7e-10 40.8 0.0 2.4e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KPI43909.1 - 3.3e-10 39.9 0.0 4.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KPI43909.1 - 1.1e-06 29.2 0.8 6.8e-06 26.6 0.4 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain ATPase PF06745.13 KPI43909.1 - 3.1e-06 26.7 0.2 6e-06 25.8 0.2 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KPI43909.1 - 0.0052 16.1 0.3 0.04 13.3 0.1 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KPI43909.1 - 0.07 13.4 0.1 0.21 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KPI43909.1 - 0.073 13.1 0.3 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KPI43909.1 - 0.073 12.2 2.0 0.24 10.5 0.6 2.0 1 1 1 2 2 2 0 PAXNEB protein UFD1 PF03152.14 KPI43910.1 - 2.9e-26 92.0 0.0 2.2e-22 79.4 0.0 3.7 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KPI43910.1 - 0.004 17.3 0.1 0.016 15.4 0.1 2.0 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-PARP PF00645.18 KPI43910.1 - 0.12 13.2 1.5 0.55 11.1 1.5 2.1 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF4428 PF14471.6 KPI43910.1 - 0.24 11.3 2.9 5.3 7.1 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) zf_C2HC_14 PF18574.1 KPI43910.1 - 0.54 10.1 6.0 0.1 12.4 0.6 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain zf-TRAF PF02176.18 KPI43910.1 - 1.8 9.3 17.3 0.13 13.0 1.0 3.2 3 0 0 3 3 3 0 TRAF-type zinc finger E1_DerP2_DerF2 PF02221.15 KPI43911.1 - 8.2e-20 71.6 1.1 7.3e-19 68.5 1.1 2.1 1 1 0 1 1 1 1 ML domain Big_9 PF17963.1 KPI43911.1 - 5.3e-05 23.9 0.1 9.4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial Ig domain Glyco_hydro_64 PF16483.5 KPI43912.1 - 3.3e-92 309.6 2.1 6.1e-92 308.7 2.1 1.4 1 0 0 1 1 1 1 Beta-1,3-glucanase ERG4_ERG24 PF01222.17 KPI43913.1 - 3.9e-140 467.4 19.6 4.9e-140 467.1 19.6 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FAD_binding_3 PF01494.19 KPI43913.1 - 2.3e-20 73.2 1.3 1.1e-17 64.3 1.3 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI43913.1 - 1.3e-09 38.1 2.1 7.6e-06 25.7 0.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI43913.1 - 5.4e-08 32.4 1.0 0.00094 18.5 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPI43913.1 - 3.4e-07 29.6 0.0 3.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KPI43913.1 - 1.4e-05 25.2 0.1 4.3e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KPI43913.1 - 8e-05 22.1 0.9 0.26 10.5 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPI43913.1 - 0.00011 22.7 0.2 0.0026 18.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI43913.1 - 0.0003 20.0 0.5 0.00054 19.1 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KPI43913.1 - 0.0016 18.1 0.2 0.0031 17.2 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KPI43913.1 - 0.0022 17.1 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPI43913.1 - 0.0027 16.5 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPI43913.1 - 0.046 13.1 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPI43913.1 - 0.18 10.6 0.6 1.5 7.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KPI43913.1 - 0.24 10.6 0.0 1.1 8.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_12 PF13424.6 KPI43914.1 - 2.3e-09 37.4 4.1 0.0033 17.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Clr5 PF14420.6 KPI43914.1 - 4.9e-07 29.9 1.5 6.8e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Clr5 domain TPR_10 PF13374.6 KPI43914.1 - 1.1 9.2 9.5 8.9 6.3 0.5 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.23 KPI43915.1 - 1.5e-13 50.8 1.9 2.1e-11 43.9 0.7 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Xpo1 PF08389.12 KPI43915.1 - 0.019 15.0 0.1 0.026 14.6 0.1 1.2 1 0 0 1 1 1 0 Exportin 1-like protein Histone PF00125.24 KPI43915.1 - 0.021 15.2 0.1 0.049 14.0 0.1 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 GIDA_assoc PF13932.6 KPI43915.1 - 0.042 14.0 0.7 0.047 13.9 0.7 1.1 1 0 0 1 1 1 0 GidA associated domain Bromo_TP PF07524.13 KPI43915.1 - 0.047 13.7 0.2 0.078 13.0 0.2 1.3 1 0 0 1 1 1 0 Bromodomain associated Ecm29 PF13001.7 KPI43915.1 - 0.056 12.1 0.1 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 Proteasome stabiliser UBX PF00789.20 KPI43916.1 - 4.4e-12 46.0 0.0 8.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KPI43916.1 - 9e-10 38.2 0.1 1.7e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Paramyxo_ncap PF00973.19 KPI43916.1 - 0.88 8.4 4.7 1.2 8.0 4.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 KPI43916.1 - 1.6 7.4 4.6 2.3 6.9 4.6 1.2 1 0 0 1 1 1 0 Presenilin ApbA_C PF08546.11 KPI43917.1 - 9.8e-29 100.1 0.1 1.4e-28 99.6 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KPI43917.1 - 5.6e-25 87.7 0.0 7.5e-24 84.1 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MMR_HSR1_C PF08438.10 KPI43917.1 - 0.098 13.2 0.2 0.23 12.1 0.2 1.6 1 0 0 1 1 1 0 GTPase of unknown function C-terminal ADH_zinc_N PF00107.26 KPI43918.1 - 3.9e-25 88.3 0.0 9e-25 87.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI43918.1 - 3.1e-18 65.7 0.0 5.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KPI43918.1 - 5.3e-08 34.0 0.0 1.1e-07 33.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PDGLE PF13190.6 KPI43918.1 - 0.12 12.3 0.0 0.74 9.8 0.0 2.2 2 1 1 3 3 3 0 PDGLE domain Mito_carr PF00153.27 KPI43919.1 - 3.4e-40 135.9 0.5 1.5e-20 72.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1772 PF08592.11 KPI43921.1 - 1.7e-17 64.0 4.7 2.2e-17 63.7 4.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pyr_redox_2 PF07992.14 KPI43922.1 - 2.4e-14 53.3 0.0 1.4e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI43922.1 - 1e-13 51.3 0.0 4.8e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI43922.1 - 3.5e-11 42.3 0.0 4.2e-08 32.1 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI43922.1 - 2.1e-09 37.4 0.0 3.8e-08 33.4 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI43922.1 - 7.9e-05 22.7 0.3 0.06 13.3 0.1 3.8 3 2 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KPI43922.1 - 0.00039 20.8 0.0 0.93 10.0 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 KPI43922.1 - 0.0038 17.8 0.1 0.96 10.1 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Vsr PF03852.15 KPI43922.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr FAD_binding_2 PF00890.24 KPI43922.1 - 0.038 13.1 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPI43922.1 - 0.039 13.2 0.0 2.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.20 KPI43922.1 - 0.043 13.9 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KPI43922.1 - 0.049 12.8 0.0 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KPI43922.1 - 0.051 12.9 0.1 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KPI43922.1 - 0.076 12.6 0.5 0.8 9.2 0.0 2.7 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KPI43922.1 - 0.21 10.8 1.2 2.9 7.0 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain RIC1 PF07064.13 KPI43923.1 - 2.2e-10 40.4 0.0 4.9e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 RIC1 FAM176 PF14851.6 KPI43923.1 - 0.38 10.4 3.0 0.63 9.7 3.0 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 KPI43923.1 - 0.39 9.9 1.9 0.48 9.6 1.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KPI43923.1 - 0.77 7.8 10.7 0.99 7.4 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KPI43923.1 - 1.6 6.9 9.2 1.9 6.6 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KPI43923.1 - 1.7 7.7 12.8 2.3 7.3 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KPI43923.1 - 3.1 6.0 6.7 4 5.6 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KPI43923.1 - 6 5.3 5.5 7.6 4.9 5.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NTP_transf_2 PF01909.23 KPI43924.1 - 1.7e-07 31.4 0.0 3.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KPI43924.1 - 6.1e-06 26.3 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Filaggrin PF03516.13 KPI43924.1 - 4.1 8.2 8.0 3 8.6 1.8 2.7 2 0 0 2 2 2 0 Filaggrin Pkinase PF00069.25 KPI43925.1 - 3.2e-72 243.1 0.0 3.9e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43925.1 - 5.5e-29 101.2 0.0 7.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI43925.1 - 9.6e-08 31.7 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPI43925.1 - 0.00012 21.0 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KPI43925.1 - 0.00043 20.3 0.1 0.00072 19.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KPI43925.1 - 0.00089 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NmrA PF05368.13 KPI43926.1 - 1.7e-27 96.5 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI43926.1 - 5.1e-12 46.0 0.0 8.3e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI43926.1 - 3.4e-05 23.4 0.1 6.5e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KPI43926.1 - 0.00014 22.3 0.0 0.00094 19.6 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPI43926.1 - 0.00016 21.9 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KPI43926.1 - 0.00064 18.9 0.1 0.00088 18.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KPI43926.1 - 0.0018 18.2 0.1 0.0033 17.4 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KPI43926.1 - 0.0019 17.3 0.3 0.0027 16.8 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KPI43926.1 - 0.07 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KPI43926.1 - 0.083 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KPI43926.1 - 0.096 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GFO_IDH_MocA PF01408.22 KPI43926.1 - 0.18 12.7 0.0 0.45 11.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.12 KPI43926.1 - 0.19 10.9 0.0 0.83 8.8 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Glyco_hydro_47 PF01532.20 KPI43927.1 - 1.5e-105 353.8 0.0 2.3e-105 353.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.22 KPI43929.1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KPI43929.1 - 0.00036 20.5 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KPI43929.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KPI43929.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif zf-CCHC_6 PF15288.6 KPI43930.1 - 0.011 15.6 4.6 0.027 14.3 4.6 1.7 1 0 0 1 1 1 0 Zinc knuckle FMN_dh PF01070.18 KPI43931.1 - 1.4e-120 402.5 0.0 1.7e-120 402.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPI43931.1 - 4.3e-22 78.0 0.0 9.9e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KPI43931.1 - 8.8e-09 35.0 0.1 1.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPI43931.1 - 3.5e-05 23.0 0.4 0.0002 20.5 0.1 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPI43931.1 - 0.017 14.5 0.3 0.03 13.7 0.3 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 KPI43931.1 - 0.078 12.4 0.7 0.78 9.1 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KPI43931.1 - 0.15 11.3 0.0 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DNA_pol_B_palm PF14792.6 KPI43932.1 - 1.2e-31 109.3 0.0 8.4e-31 106.5 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KPI43932.1 - 1.2e-17 63.5 2.6 2.1e-17 62.7 0.1 2.7 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KPI43932.1 - 1.4e-16 60.6 2.1 3e-16 59.5 2.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 KPI43932.1 - 5.5e-10 39.3 0.3 1.6e-09 37.8 0.3 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb BRCT PF00533.26 KPI43932.1 - 0.00046 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KPI43932.1 - 0.022 15.0 0.0 0.068 13.5 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain BRCT_2 PF16589.5 KPI43932.1 - 0.058 13.8 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Gtr1_RagA PF04670.12 KPI43933.1 - 6.6e-59 199.1 0.1 9.2e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KPI43933.1 - 0.00026 21.2 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI43933.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KPI43933.1 - 0.017 15.5 0.0 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KPI43933.1 - 0.044 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain TFIIA_gamma_N PF02268.16 KPI43933.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Senescence_reg PF04520.13 KPI43934.1 - 1.7 9.5 8.1 0.54 11.1 5.0 1.7 1 1 1 2 2 2 0 Senescence regulator Fungal_trans_2 PF11951.8 KPI43935.1 - 0.001 18.0 1.0 0.0017 17.3 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI43936.1 - 9.7e-09 35.2 7.2 1.6e-08 34.5 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KPI43936.1 - 3e-06 26.5 1.4 5.9e-06 25.5 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arg_decarbox_C PF17944.1 KPI43936.1 - 0.17 12.5 0.5 0.39 11.3 0.5 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension AA_permease_2 PF13520.6 KPI43937.1 - 1.6e-40 139.3 54.1 1.4e-39 136.1 54.1 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI43937.1 - 2e-15 56.4 46.7 1.6e-14 53.4 46.7 1.9 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.22 KPI43938.1 - 5.9e-66 223.1 0.0 6.7e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyridoxal_deC PF00282.19 KPI43939.1 - 8.8e-100 334.0 0.0 1.1e-99 333.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KPI43939.1 - 0.0081 15.4 0.0 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Fungal_trans_2 PF11951.8 KPI43940.1 - 1.3e-10 40.6 0.0 2.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KPI43941.1 - 4.1e-14 52.6 0.9 2.6e-12 46.7 0.9 2.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI43941.1 - 2e-09 37.1 0.2 7.7e-06 25.3 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI43941.1 - 1.3e-07 31.1 0.2 2.7e-07 30.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI43941.1 - 5.9e-06 26.4 0.1 1.5e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI43941.1 - 1.4e-05 24.8 0.4 0.00051 19.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KPI43941.1 - 0.00021 20.8 1.0 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI43941.1 - 0.00043 19.1 0.0 0.00088 18.1 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KPI43941.1 - 0.0014 19.1 0.1 0.056 14.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI43941.1 - 0.0016 17.6 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KPI43941.1 - 0.0079 15.5 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KPI43941.1 - 0.047 12.9 0.5 0.095 11.9 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI43941.1 - 0.089 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TauD PF02668.16 KPI43942.1 - 1.4e-59 202.1 0.5 1.7e-59 201.8 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ATG_C PF09333.11 KPI43942.1 - 0.15 12.4 0.1 0.39 11.1 0.0 1.6 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain VPS9 PF02204.18 KPI43943.1 - 3e-29 101.3 0.0 5.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KPI43943.1 - 7.8e-15 54.9 0.2 1.8e-14 53.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KPI43943.1 - 5e-08 32.5 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain TMA7 PF09072.10 KPI43944.1 - 1.3e-25 90.0 24.5 1.5e-25 89.8 24.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Cyt-b5 PF00173.28 KPI43945.1 - 5.2e-12 45.7 0.0 8.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fapy_DNA_glyco PF01149.24 KPI43946.1 - 1.4e-31 109.5 0.0 3.1e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KPI43946.1 - 2.3e-21 75.6 0.0 4.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KPI43946.1 - 0.00094 18.0 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Amidohydro_2 PF04909.14 KPI43947.1 - 7.3e-38 131.0 0.3 8.7e-38 130.8 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase F-box PF00646.33 KPI43948.1 - 0.0027 17.6 2.8 0.0037 17.1 0.1 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KPI43948.1 - 0.0045 16.9 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KPI43948.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 KPI43948.1 - 9.7 6.8 7.0 1.2e+02 3.4 0.7 4.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Pyr_redox_3 PF13738.6 KPI43950.1 - 6.3e-17 61.8 0.0 2.5e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI43950.1 - 3.9e-14 52.6 0.0 4.3e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI43950.1 - 9.7e-14 51.2 0.0 1e-11 44.6 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPI43950.1 - 8.2e-12 44.3 0.0 5.8e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KPI43950.1 - 3e-06 27.3 0.0 0.07 13.1 0.1 3.3 2 1 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KPI43950.1 - 1e-05 24.9 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KPI43950.1 - 0.00011 22.3 0.0 0.00035 20.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI43950.1 - 0.00013 21.7 0.3 0.025 14.2 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI43950.1 - 0.00033 19.5 0.0 1.4 7.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KPI43950.1 - 0.0084 15.2 0.0 10 5.1 0.0 3.7 4 0 0 4 4 4 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KPI43950.1 - 0.029 13.7 0.0 6.7 5.9 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KPI43950.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.6 1 1 1 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KPI43950.1 - 0.055 14.0 0.3 17 6.0 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DIOX_N PF14226.6 KPI43951.1 - 3.2e-21 76.2 0.0 4.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI43951.1 - 3e-17 62.9 0.0 1.9e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_M28 PF04389.17 KPI43952.1 - 1.3e-36 126.1 0.0 2.3e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KPI43952.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ADH_N PF08240.12 KPI43954.1 - 7.4e-27 93.4 1.3 1.6e-26 92.3 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI43954.1 - 5.2e-16 58.8 0.0 8.2e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI43954.1 - 6e-05 22.6 1.8 0.0044 16.5 1.8 2.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Tctex-1 PF03645.13 KPI43955.1 - 4.3e-33 113.6 0.0 6.3e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF3636 PF12331.8 KPI43955.1 - 0.098 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Bunya_RdRp PF04196.12 KPI43955.1 - 0.2 10.0 0.1 0.29 9.4 0.1 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase bZIP_1 PF00170.21 KPI43956.1 - 1.7e-05 24.8 14.5 3.2e-05 23.9 14.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KPI43956.1 - 0.00098 19.2 14.4 0.0019 18.2 14.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper SAGA-Tad1 PF12767.7 KPI43956.1 - 0.043 13.6 4.5 0.066 12.9 4.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HAD_2 PF13419.6 KPI43957.1 - 6.8e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI43957.1 - 1.8e-06 28.4 0.0 2.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI43957.1 - 0.0091 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Sugar_tr PF00083.24 KPI43958.1 - 2.1e-38 132.4 23.7 4.4e-37 128.0 23.7 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI43958.1 - 1.4e-31 109.8 25.5 2.5e-25 89.2 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_34 PF05637.12 KPI43959.1 - 2.9e-13 50.1 2.5 3.7e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KPI43959.1 - 6.8e-05 22.5 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 AAA_2 PF07724.14 KPI43960.1 - 2.9e-47 161.0 0.0 5.1e-46 156.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KPI43960.1 - 8.8e-36 122.0 2.4 8.8e-36 122.0 2.4 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KPI43960.1 - 6.3e-25 87.0 0.1 2.3e-24 85.2 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KPI43960.1 - 4.8e-19 69.1 0.0 6.2e-09 36.4 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPI43960.1 - 2.5e-14 53.5 0.1 2.6e-09 37.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI43960.1 - 1.7e-11 44.8 4.5 0.00013 22.4 0.4 4.3 2 2 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KPI43960.1 - 1.8e-08 34.2 0.2 0.00019 21.2 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KPI43960.1 - 3.7e-08 33.7 1.1 0.011 16.0 0.0 3.4 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KPI43960.1 - 5.6e-07 29.7 0.0 0.034 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KPI43960.1 - 9.9e-06 25.6 4.3 0.98 9.3 0.1 4.3 2 2 0 3 3 3 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KPI43960.1 - 1e-05 25.4 0.0 0.029 14.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KPI43960.1 - 1.7e-05 25.1 0.5 0.049 13.9 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KPI43960.1 - 2.4e-05 23.9 0.0 0.18 11.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 KPI43960.1 - 2.4e-05 24.3 0.1 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ABC_tran PF00005.27 KPI43960.1 - 0.00013 22.5 2.0 0.75 10.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 KPI43960.1 - 0.00019 22.0 3.9 0.11 13.1 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_24 PF13479.6 KPI43960.1 - 0.00024 20.9 0.0 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KPI43960.1 - 0.0006 19.2 0.1 4.2 6.7 0.0 3.8 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KPI43960.1 - 0.0007 20.0 0.0 0.37 11.2 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KPI43960.1 - 0.0013 18.5 0.0 0.14 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KPI43960.1 - 0.0017 18.9 11.2 0.2 12.1 11.2 2.7 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KPI43960.1 - 0.0023 18.1 0.0 0.94 9.7 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 KPI43960.1 - 0.0035 17.3 0.3 6 6.8 0.0 3.3 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KPI43960.1 - 0.0036 17.3 0.1 3.3 7.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KPI43960.1 - 0.0045 17.3 1.3 0.18 12.1 0.2 3.4 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI43960.1 - 0.0047 16.8 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 KPI43960.1 - 0.0091 15.6 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KPI43960.1 - 0.01 15.1 0.0 1.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KPI43960.1 - 0.01 16.0 0.0 8.1 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KPI43960.1 - 0.016 14.8 0.3 1.3 8.5 0.1 3.0 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KPI43960.1 - 0.02 14.6 0.1 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.9 KPI43960.1 - 0.026 13.5 0.0 0.67 8.8 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 KPI43960.1 - 0.03 13.5 0.3 0.66 9.1 0.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF815) PIF1 PF05970.14 KPI43960.1 - 0.032 13.4 0.0 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 PIF1-like helicase ATP_bind_1 PF03029.17 KPI43960.1 - 0.041 13.7 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 KPI43960.1 - 0.041 13.3 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein CLP1_P PF16575.5 KPI43960.1 - 0.054 13.3 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_6 PF12774.7 KPI43960.1 - 0.061 12.3 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 KPI43960.1 - 0.065 13.0 4.6 0.65 9.8 0.0 3.3 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPI43960.1 - 0.076 12.8 0.1 7.8 6.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain UvrD-helicase PF00580.21 KPI43960.1 - 0.12 11.8 3.8 0.54 9.7 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Rootletin PF15035.6 KPI43960.1 - 0.18 11.8 9.1 0.35 10.9 9.1 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 KPI43960.1 - 0.4 10.0 6.7 0.69 9.2 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KPI43960.1 - 0.43 9.4 1.0 0.74 8.6 0.6 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein GrpE PF01025.19 KPI43960.1 - 0.98 9.1 7.1 2.5 7.7 6.6 2.0 2 0 0 2 2 1 0 GrpE DUF4094 PF13334.6 KPI43960.1 - 1.8 9.0 4.5 1.1 9.7 0.5 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) CENP-F_leu_zip PF10473.9 KPI43960.1 - 2.1 8.4 13.7 39 4.3 13.7 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KPI43960.1 - 4.4 7.1 12.4 3 7.7 6.4 2.4 1 1 1 2 2 2 0 Septum formation initiator AMP-binding PF00501.28 KPI43961.1 - 2e-94 316.6 0.0 2.5e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI43961.1 - 6.5e-09 36.6 0.0 1.3e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MTHFR PF02219.17 KPI43962.1 - 1.7e-115 385.3 0.0 2.2e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pox_T4_C PF04490.12 KPI43962.1 - 0.12 12.5 0.0 6.9 6.8 0.0 2.5 3 0 0 3 3 3 0 Poxvirus T4 protein, C terminus SCO1-SenC PF02630.14 KPI43965.1 - 1.2e-45 154.7 0.0 1.7e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KPI43965.1 - 0.00017 21.5 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KPI43965.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like FAD_binding_3 PF01494.19 KPI43966.1 - 1.3e-90 304.2 0.0 1.8e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI43966.1 - 1.4e-05 24.5 0.0 0.0026 17.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI43966.1 - 0.0016 18.1 0.0 1.6 8.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI43966.1 - 0.002 18.6 0.1 3.2 8.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI43966.1 - 0.0085 16.3 0.3 0.022 15.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI43966.1 - 0.032 13.3 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DUF1684 PF07920.11 KPI43967.1 - 0.0085 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1684) DUF4858 PF16150.5 KPI43967.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) Aminotran_4 PF01063.19 KPI43968.1 - 3.1e-39 135.1 0.0 4.1e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Beta_elim_lyase PF01212.21 KPI43968.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4448 PF14610.6 KPI43970.1 - 8.1e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KPI43970.1 - 0.00045 19.6 2.8 0.0009 18.6 2.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KPI43970.1 - 0.0087 15.9 0.4 0.018 14.9 0.4 1.8 1 1 0 1 1 1 1 Transmembrane protein 51 DAP10 PF07213.11 KPI43970.1 - 0.016 15.2 0.9 0.039 13.9 0.9 1.6 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 KPI43970.1 - 0.15 13.0 0.0 0.31 11.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 KPI43970.1 - 0.26 11.9 1.9 4.3 8.0 1.9 2.5 1 1 0 1 1 1 0 WW domain-binding protein 1 TMEM154 PF15102.6 KPI43970.1 - 0.48 10.3 11.6 0.19 11.6 6.0 2.8 2 1 0 2 2 2 0 TMEM154 protein family RCR PF12273.8 KPI43970.1 - 1.6 9.4 7.3 0.66 10.6 3.6 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.15 KPI43970.1 - 8.7 6.2 6.4 1.1 9.1 1.9 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Methyltr_RsmB-F PF01189.17 KPI43972.1 - 1.5e-31 109.6 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 KPI43972.1 - 0.00016 21.3 0.1 0.0004 20.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KPI43972.1 - 0.00021 21.4 0.0 0.00039 20.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 KPI43972.1 - 0.031 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 KPI43972.1 - 0.17 12.6 0.0 1.6 9.5 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain NmrA PF05368.13 KPI43974.1 - 7.1e-11 42.1 0.0 9.9e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI43974.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AA_permease_2 PF13520.6 KPI43975.1 - 9.8e-57 192.7 57.1 1.3e-56 192.2 57.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI43975.1 - 7.6e-16 57.8 45.6 1.1e-15 57.2 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease rRNA_proc-arch PF13234.6 KPI43976.1 - 1.1e-82 278.0 0.1 3.1e-82 276.6 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KPI43976.1 - 2.2e-54 183.5 2.5 2.4e-54 183.4 0.9 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KPI43976.1 - 1.1e-18 67.7 0.0 3.4e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI43976.1 - 5.3e-06 26.5 0.6 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI43976.1 - 7.2e-06 26.3 0.0 2.7e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KPI43976.1 - 0.007 15.5 0.0 0.024 13.7 0.0 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 KPI43976.1 - 0.068 12.5 0.3 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 KPI43976.1 - 0.14 12.4 0.0 0.59 10.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AnmK PF03702.14 KPI43977.1 - 2e-60 204.9 0.0 2.3e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 KPI43977.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.16 KPI43978.1 - 5.5e-25 88.0 19.9 5.5e-25 88.0 19.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DAO PF01266.24 KPI43979.1 - 1.1e-30 107.4 2.2 2.4e-30 106.3 2.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 KPI43979.1 - 7.7e-09 35.4 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 KPI43979.1 - 1.2e-08 35.0 0.3 3.6e-08 33.5 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI43979.1 - 3.7e-06 26.3 0.4 5.9e-06 25.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KPI43979.1 - 1.1e-05 24.9 0.1 1.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI43979.1 - 2.4e-05 23.7 0.1 4.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI43979.1 - 0.00055 19.2 0.0 0.00092 18.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KPI43979.1 - 0.0011 18.4 0.8 0.0016 17.9 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI43979.1 - 0.0012 18.2 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI43979.1 - 0.0055 16.0 2.1 0.0066 15.8 0.2 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KPI43979.1 - 0.014 15.9 1.0 0.029 14.9 0.1 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI43979.1 - 0.015 14.0 0.2 0.022 13.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KPI43979.1 - 0.12 11.4 0.2 0.23 10.5 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A LacAB_rpiB PF02502.18 KPI43980.1 - 7.9e-46 155.5 0.5 9e-46 155.3 0.5 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KPI43980.1 - 0.008 16.2 0.0 0.012 15.7 0.0 1.3 1 1 0 1 1 1 1 Glycine-rich SFCGS DUF2620 PF10941.8 KPI43980.1 - 0.018 15.1 0.7 0.026 14.6 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF2620 AA_permease_2 PF13520.6 KPI43982.1 - 1.8e-55 188.5 53.7 2.2e-55 188.2 53.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI43982.1 - 3.6e-21 75.3 40.1 4.9e-21 74.9 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease MDD_C PF18376.1 KPI43984.1 - 3.8e-63 212.6 0.0 5.8e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KPI43984.1 - 2e-08 34.3 1.1 4.5e-08 33.2 1.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain COesterase PF00135.28 KPI43985.1 - 9.3e-62 209.5 0.4 1.7e-59 202.0 0.0 2.1 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI43985.1 - 2.1e-10 40.8 0.1 6.5e-10 39.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DHO_dh PF01180.21 KPI43986.1 - 3.3e-39 134.9 0.0 4.9e-28 98.2 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.17 KPI43986.1 - 0.00022 20.7 0.2 0.32 10.4 0.0 2.3 2 0 0 2 2 2 2 PcrB family DUF4407 PF14362.6 KPI43986.1 - 0.028 13.8 4.5 0.039 13.3 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FH2 PF02181.23 KPI43986.1 - 0.12 11.5 1.2 0.18 10.9 1.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain TMEM247 PF15444.6 KPI43986.1 - 0.22 11.5 1.1 3.7 7.5 0.4 2.1 1 1 1 2 2 2 0 Transmembrane protein 247 DASH_Spc19 PF08287.11 KPI43986.1 - 0.31 10.9 6.2 0.54 10.1 6.2 1.3 1 0 0 1 1 1 0 Spc19 MFS_1 PF07690.16 KPI43987.1 - 4.2e-30 104.9 49.5 4.2e-30 104.9 49.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_II PF00596.21 KPI43988.1 - 1.3e-47 162.2 0.1 1.6e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DIOX_N PF14226.6 KPI43989.1 - 2.3e-21 76.8 0.0 3.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI43989.1 - 1.2e-15 57.8 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DHO_dh PF01180.21 KPI43990.1 - 8.7e-11 41.6 0.1 1.1e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase bPH_5 PF10882.8 KPI43990.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Hexapep PF00132.24 KPI43991.1 - 3e-07 29.9 6.9 0.0033 17.1 1.1 3.9 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KPI43991.1 - 0.00053 20.4 0.0 0.00093 19.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KPI43991.1 - 0.0039 15.4 1.8 0.006 14.8 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KPI43991.1 - 0.026 13.5 0.1 0.046 12.7 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 KPI43991.1 - 0.57 10.0 9.0 1.4 8.7 2.0 3.3 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Pyr_redox_2 PF07992.14 KPI43992.1 - 5.3e-31 107.9 0.0 1.9e-30 106.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI43992.1 - 8.7e-07 29.4 3.8 7e-06 26.5 0.2 3.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI43992.1 - 0.1 12.6 0.0 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAA_hydrolase PF01557.18 KPI43993.1 - 3.9e-26 92.1 0.1 5.8e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 KPI43993.1 - 2e-12 47.3 0.4 1.9e-10 40.9 0.1 2.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI43993.1 - 3.4e-12 47.4 2.3 3.6e-11 44.1 0.7 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI43993.1 - 1.8e-08 34.0 0.3 5.8e-08 32.3 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KPI43993.1 - 1.8e-05 24.7 0.7 0.00021 21.2 0.7 2.2 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_4 PF08386.10 KPI43993.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_8 PF06259.12 KPI43993.1 - 0.032 13.9 2.3 0.072 12.7 0.1 2.6 2 1 2 4 4 4 0 Alpha/beta hydrolase PGAP1 PF07819.13 KPI43993.1 - 0.088 12.5 0.7 0.34 10.6 0.1 2.0 1 1 1 2 2 2 0 PGAP1-like protein DUF676 PF05057.14 KPI43993.1 - 0.12 11.8 1.4 1.9 8.0 0.3 2.2 1 1 1 2 2 2 0 Putative serine esterase (DUF676) adh_short_C2 PF13561.6 KPI43995.1 - 9.4e-38 130.1 0.1 1.1e-37 129.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI43995.1 - 6.3e-34 117.1 0.0 7.7e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI43995.1 - 1.6e-06 28.1 0.2 4.6e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI43995.1 - 0.0011 18.5 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI43995.1 - 0.006 15.8 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KPI43995.1 - 0.029 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPI43995.1 - 0.058 12.5 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ThiF PF00899.21 KPI43995.1 - 0.19 11.0 0.4 0.51 9.7 0.1 1.7 2 0 0 2 2 2 0 ThiF family AAA PF00004.29 KPI43996.1 - 5.3e-44 149.8 0.0 8.3e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI43996.1 - 3.2e-15 55.7 0.1 7.7e-15 54.4 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KPI43996.1 - 1.5e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KPI43996.1 - 4.6e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI43996.1 - 6.8e-07 29.8 0.0 4.3e-05 24.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KPI43996.1 - 3.3e-06 27.0 2.1 8.5e-06 25.6 2.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KPI43996.1 - 1.5e-05 25.3 0.1 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KPI43996.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KPI43996.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KPI43996.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KPI43996.1 - 0.002 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPI43996.1 - 0.0055 17.2 0.0 0.029 14.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 KPI43996.1 - 0.0057 16.5 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KPI43996.1 - 0.0078 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KPI43996.1 - 0.0078 15.6 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KPI43996.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KPI43996.1 - 0.012 15.9 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KPI43996.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KPI43996.1 - 0.023 14.4 0.0 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KPI43996.1 - 0.026 14.0 0.0 0.098 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KPI43996.1 - 0.03 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KPI43996.1 - 0.039 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KPI43996.1 - 0.041 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPI43996.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KPI43996.1 - 0.058 13.1 0.1 0.21 11.3 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 KPI43996.1 - 0.068 12.7 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KPI43996.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KPI43996.1 - 0.13 11.6 0.1 0.28 10.4 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin DUF2072 PF09845.9 KPI43996.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein HR1 PF02185.16 KPI43996.1 - 0.24 11.6 2.6 0.47 10.6 1.9 1.8 1 1 0 1 1 1 0 Hr1 repeat CorA PF01544.18 KPI43997.1 - 0.002 17.5 0.2 0.0034 16.7 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KPI43998.1 - 2.3e-52 178.0 0.0 3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI43998.1 - 1.4e-32 113.0 0.0 1.7e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI43998.1 - 3.8e-07 29.7 0.0 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KPI43998.1 - 0.0027 17.1 0.2 0.0042 16.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI43998.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KPI43998.1 - 0.057 12.4 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 KPI43998.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DAO PF01266.24 KPI43999.1 - 4.5e-33 115.3 0.3 5.5e-33 115.0 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI43999.1 - 6.1e-06 26.4 0.1 1.7e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KPI43999.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KPI43999.1 - 0.00026 21.0 0.1 0.013 15.5 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI43999.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI43999.1 - 0.0019 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KPI43999.1 - 0.014 14.8 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KPI43999.1 - 0.031 13.3 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KPI43999.1 - 0.052 14.1 0.2 0.11 13.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KPI43999.1 - 0.075 12.9 0.1 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KPI43999.1 - 0.16 11.2 0.0 7.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sterol_MT_C PF08498.10 KPI44000.1 - 1.5e-28 98.8 0.4 2.8e-28 98.0 0.4 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KPI44000.1 - 1.2e-14 54.7 0.0 2.3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI44000.1 - 1.1e-13 51.7 0.0 2.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI44000.1 - 8.3e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KPI44000.1 - 5.6e-10 39.0 0.0 7.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KPI44000.1 - 8.2e-09 35.5 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI44000.1 - 9.8e-09 35.9 0.0 2.9e-08 34.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI44000.1 - 4.8e-05 22.8 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KPI44000.1 - 0.00027 19.7 0.0 0.00037 19.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 KPI44000.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DRE2_N PF16803.5 KPI44000.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus LSM PF01423.22 KPI44001.1 - 1.4e-17 63.1 0.1 2.2e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain Tyr-DNA_phospho PF06087.12 KPI44002.1 - 1.5e-129 432.7 0.0 1.9e-129 432.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Sigma70_r4_2 PF08281.12 KPI44002.1 - 0.0028 17.3 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 PLDc_2 PF13091.6 KPI44002.1 - 0.035 14.0 0.0 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain ABC2_membrane PF01061.24 KPI44003.1 - 8e-63 211.6 64.8 3.2e-43 147.6 18.2 4.3 5 0 0 5 5 4 3 ABC-2 type transporter PDR_CDR PF06422.12 KPI44003.1 - 1.3e-30 105.1 3.8 2.8e-26 91.2 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KPI44003.1 - 3e-14 53.7 0.0 5.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KPI44003.1 - 3.9e-05 22.9 36.0 0.00099 18.3 19.1 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KPI44003.1 - 8.7e-05 22.5 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KPI44003.1 - 0.00012 22.0 1.2 0.01 15.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KPI44003.1 - 0.00081 19.9 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KPI44003.1 - 0.0025 17.5 0.0 0.0095 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KPI44003.1 - 0.0034 17.0 0.4 0.0092 15.6 0.3 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KPI44003.1 - 0.0083 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPI44003.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KPI44003.1 - 0.016 15.6 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KPI44003.1 - 0.022 14.2 0.5 0.11 11.9 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KPI44003.1 - 0.045 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KPI44003.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FliG_C PF01706.16 KPI44003.1 - 0.16 12.2 0.0 0.99 9.6 0.0 2.2 2 0 0 2 2 2 0 FliG C-terminal domain AAA_29 PF13555.6 KPI44003.1 - 0.16 11.7 0.2 0.43 10.3 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KPI44003.1 - 0.28 10.4 0.2 0.55 9.5 0.2 1.4 1 0 0 1 1 1 0 Septin DUF3597 PF12200.8 KPI44003.1 - 0.83 10.2 2.5 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) TPP_enzyme_N PF02776.18 KPI44004.1 - 2.4e-37 128.2 0.0 5.2e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KPI44004.1 - 1.5e-17 63.8 0.0 3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI44004.1 - 2.3e-10 40.3 0.0 6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain OmpH PF03938.14 KPI44004.1 - 0.017 15.5 0.9 0.031 14.6 0.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sulfate_transp PF00916.20 KPI44005.1 - 1.1e-47 162.6 11.5 2.3e-40 138.5 2.5 2.2 2 0 0 2 2 2 2 Sulfate permease family cNMP_binding PF00027.29 KPI44005.1 - 1.6e-13 50.6 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KPI44005.1 - 1e-11 44.5 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KPI44005.1 - 5.8 7.4 16.7 4.3 7.8 4.8 3.7 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily adh_short PF00106.25 KPI44006.1 - 1.5e-38 132.2 0.1 1.9e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44006.1 - 2.3e-23 83.0 0.0 2.7e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44006.1 - 2.7e-11 43.7 0.1 3.9e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Romo1 PF10247.9 KPI44007.1 - 3.6e-25 88.1 17.7 4.5e-25 87.8 17.7 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KPI44007.1 - 0.071 13.5 7.2 0.093 13.1 7.2 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Amidohydro_1 PF01979.20 KPI44008.1 - 1.8e-21 76.8 0.7 2.6e-21 76.3 0.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family FAA_hydrolase PF01557.18 KPI44008.1 - 1.4e-12 47.7 0.0 2.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Amidohydro_3 PF07969.11 KPI44008.1 - 6.6e-09 35.7 5.3 1.9e-05 24.3 3.0 4.0 2 1 0 2 2 2 2 Amidohydrolase family Sugar_tr PF00083.24 KPI44009.1 - 3.1e-82 276.9 20.2 3.6e-82 276.6 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44009.1 - 2.8e-22 79.1 27.7 1.6e-18 66.8 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPI44009.1 - 8.1 4.6 13.0 0.017 13.4 1.3 2.3 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF899 PF05988.12 KPI44010.1 - 3.3e-62 209.8 0.0 5.8e-62 209.0 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Ferritin_2 PF13668.6 KPI44012.1 - 4.6e-07 30.1 0.4 8.6e-07 29.2 0.4 1.5 1 0 0 1 1 1 1 Ferritin-like domain RGS PF00615.19 KPI44013.1 - 1.3e-29 102.8 0.2 5.5e-29 100.8 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KPI44013.1 - 7.5e-21 74.0 0.0 2e-16 59.8 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DNA_photolyase PF00875.18 KPI44013.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 DNA photolyase MFS_1 PF07690.16 KPI44014.1 - 2.6e-34 118.7 25.6 3.8e-34 118.1 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPI44014.1 - 0.00062 19.5 0.7 0.0018 18.0 0.7 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KPI44014.1 - 0.44 9.3 9.3 0.042 12.7 2.1 2.2 2 0 0 2 2 2 0 MFS_1 like family Ribosomal_S4e PF00900.20 KPI44015.1 - 2e-35 120.5 0.1 4.3e-35 119.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 KPI44015.1 - 2.3e-16 59.6 6.3 5e-16 58.5 6.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 KPI44015.1 - 9.9e-16 57.1 0.1 1.8e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 KPI44015.1 - 3.2e-07 29.9 0.2 7.3e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 KPI44015.1 - 0.00062 19.6 5.1 0.00062 19.6 5.1 2.3 2 0 0 2 2 2 1 KOW motif Transket_pyr PF02779.24 KPI44016.1 - 5.3e-64 215.2 0.0 8.7e-64 214.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KPI44016.1 - 1.5e-57 193.5 0.0 4.5e-57 192.0 0.0 1.9 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KPI44016.1 - 7.1e-57 192.6 0.0 1e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KPI44016.1 - 1.2e-20 72.8 1.1 3.2e-20 71.4 1.1 1.8 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro_17 PF00332.18 KPI44016.1 - 0.017 14.7 0.0 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 BioY PF02632.14 KPI44016.1 - 0.053 13.6 0.3 0.086 12.9 0.3 1.2 1 0 0 1 1 1 0 BioY family PNISR PF15996.5 KPI44017.1 - 0.25 11.6 6.8 0.34 11.2 0.5 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR LRIF1 PF15741.5 KPI44017.1 - 0.7 8.4 7.5 0.1 11.1 3.1 1.7 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 UCR_14kD PF02271.16 KPI44018.1 - 1e-43 147.4 0.4 1.2e-43 147.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Semialdhyde_dhC PF02774.18 KPI44019.1 - 3.7e-35 121.7 0.0 5.9e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KPI44019.1 - 1.2e-28 99.9 0.0 3.4e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KPI44019.1 - 0.068 13.9 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase bZIP_1 PF00170.21 KPI44020.1 - 0.0017 18.4 13.8 0.0034 17.4 13.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor PCM1_C PF15717.5 KPI44020.1 - 0.0025 16.6 0.7 0.0036 16.1 0.7 1.1 1 0 0 1 1 1 1 Pericentriolar material 1 C terminus bZIP_2 PF07716.15 KPI44020.1 - 0.046 13.8 20.1 0.19 11.8 20.1 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Ribosomal_S8e PF01201.22 KPI44020.1 - 0.13 12.4 1.2 0.2 11.8 1.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e NYD-SP28_assoc PF14775.6 KPI44020.1 - 0.42 10.8 3.5 0.67 10.1 3.2 1.5 1 1 0 1 1 1 0 Sperm tail C-terminal domain bZIP_Maf PF03131.17 KPI44020.1 - 2.8 8.5 15.1 0.19 12.3 9.8 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor zf-C2H2 PF00096.26 KPI44021.1 - 0.00022 21.5 5.1 0.044 14.2 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF2986 PF11661.8 KPI44021.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Sina PF03145.16 KPI44021.1 - 0.49 10.3 3.6 0.85 9.5 3.6 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_4 PF13894.6 KPI44021.1 - 0.54 11.3 4.3 28 5.9 0.2 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger ORC4_C PF14629.6 KPI44022.1 - 2.7e-15 56.4 0.0 5.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KPI44022.1 - 9.2e-15 55.4 2.4 1.3e-14 54.9 0.5 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI44022.1 - 3e-07 30.8 0.0 1.3e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KPI44022.1 - 0.00025 21.0 0.0 0.00078 19.4 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KPI44022.1 - 0.00039 20.4 0.2 0.0014 18.6 0.2 1.9 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KPI44022.1 - 0.0012 19.2 0.0 0.0075 16.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KPI44022.1 - 0.0031 17.9 0.0 0.017 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KPI44022.1 - 0.0032 16.8 0.2 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.6 KPI44022.1 - 0.0055 16.4 0.0 0.085 12.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KPI44022.1 - 0.009 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KPI44022.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KPI44022.1 - 0.022 14.8 0.0 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KPI44022.1 - 0.051 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KPI44022.1 - 0.053 12.7 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KPI44022.1 - 0.059 13.4 0.2 0.29 11.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KPI44022.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.19 KPI44022.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KPI44022.1 - 0.14 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KPI44022.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.7 5 1 0 5 5 5 0 AAA domain Amidase PF01425.21 KPI44023.1 - 3.3e-114 382.3 0.1 8e-65 219.5 0.7 2.0 1 1 1 2 2 2 2 Amidase T2SSE_N PF05157.15 KPI44023.1 - 0.028 14.7 0.1 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain ABC2_membrane PF01061.24 KPI44025.1 - 2.2e-28 99.1 26.6 3.3e-28 98.6 26.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KPI44025.1 - 2e-26 93.2 0.2 9.2e-26 91.0 0.1 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KPI44025.1 - 3.6e-07 30.3 0.3 0.011 15.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KPI44025.1 - 5.6e-06 26.0 0.1 2.3e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KPI44025.1 - 6.5e-06 26.1 0.2 0.00011 22.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KPI44025.1 - 2.4e-05 24.8 0.5 5.5e-05 23.6 0.2 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 KPI44025.1 - 3.8e-05 23.3 0.0 9.3e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KPI44025.1 - 0.00023 21.4 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 KPI44025.1 - 0.00031 20.0 8.1 0.00031 20.0 8.1 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein IstB_IS21 PF01695.17 KPI44025.1 - 0.00032 20.5 0.1 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 KPI44025.1 - 0.00055 20.4 0.0 0.055 13.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KPI44025.1 - 0.00076 19.8 0.0 0.0035 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPI44025.1 - 0.0011 18.7 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KPI44025.1 - 0.0024 17.6 0.1 0.0045 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPI44025.1 - 0.003 16.7 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 KPI44025.1 - 0.0031 18.0 0.0 0.0098 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KPI44025.1 - 0.0038 17.1 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 NTPase SRP54 PF00448.22 KPI44025.1 - 0.0046 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KPI44025.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 KPI44025.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KPI44025.1 - 0.0095 16.1 1.0 0.012 15.8 0.1 1.6 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 KPI44025.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KPI44025.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KPI44025.1 - 0.027 14.5 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KPI44025.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KPI44025.1 - 0.029 14.4 0.1 0.1 12.6 0.1 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KPI44025.1 - 0.037 14.5 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KPI44025.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KPI44025.1 - 0.046 14.2 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPI44025.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KPI44025.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain APS_kinase PF01583.20 KPI44025.1 - 0.061 13.2 0.3 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.6 KPI44025.1 - 0.075 13.3 0.0 0.27 11.5 0.0 2.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 KPI44025.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_19 PF13245.6 KPI44025.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI44025.1 - 0.17 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain YlmH_RBD PF17774.1 KPI44025.1 - 0.18 12.1 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH AAA_PrkA PF08298.11 KPI44025.1 - 0.21 10.5 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Abhydrolase_3 PF07859.13 KPI44026.1 - 3.8e-34 118.4 0.4 7.8e-32 110.8 0.4 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B_4 PF13691.6 KPI44027.1 - 1.3e-22 79.2 0.1 3.1e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KPI44027.1 - 1.5e-09 37.7 0.8 2.8e-08 33.5 0.1 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DUF4407 PF14362.6 KPI44027.1 - 1.2 8.4 2.9 1.5 8.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 KPI44029.1 - 4.3e-78 263.0 2.6 2.5e-77 260.4 0.7 2.0 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KPI44029.1 - 5.3e-05 22.2 0.0 9.1e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KPI44029.1 - 0.0046 16.0 0.1 0.69 8.9 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FAM176 PF14851.6 KPI44029.1 - 0.077 12.6 0.8 0.18 11.4 0.8 1.5 1 0 0 1 1 1 0 FAM176 family DUF4632 PF15451.6 KPI44029.1 - 0.14 12.3 2.3 0.32 11.1 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) His_Phos_2 PF00328.22 KPI44030.1 - 3.7e-39 135.2 0.0 4.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HATPase_c PF02518.26 KPI44031.1 - 5.3e-20 72.0 0.1 1.7e-19 70.4 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI44031.1 - 1.7e-14 53.9 0.0 6.2e-14 52.1 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KPI44031.1 - 4.7e-12 45.8 0.0 1.2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KPI44031.1 - 0.00016 22.0 0.1 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 KPI44031.1 - 0.031 14.1 0.1 0.1 12.4 0.1 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_2 PF07716.15 KPI44032.1 - 4.7e-07 29.8 8.7 7.2e-07 29.2 8.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KPI44032.1 - 0.0021 18.1 5.3 0.0034 17.4 5.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KPI44032.1 - 0.049 14.1 2.1 0.1 13.1 2.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 KPI44033.1 - 3.8e-24 85.2 0.0 7.8e-24 84.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44033.1 - 3.4e-17 62.8 0.0 8.3e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44033.1 - 8.6e-07 29.0 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI44033.1 - 0.042 13.3 0.0 0.06 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI44033.1 - 0.07 12.5 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DNA_pol_phi PF04931.13 KPI44034.1 - 1.8e-163 545.6 6.3 2.5e-163 545.1 6.3 1.2 1 0 0 1 1 1 1 DNA polymerase phi EntA_Immun PF08951.10 KPI44034.1 - 0.068 13.5 2.0 8.2 6.9 0.1 3.7 3 0 0 3 3 3 0 Enterocin A Immunity FAM83 PF07894.12 KPI44034.1 - 0.19 11.3 0.8 0.49 9.9 0.8 1.7 1 0 0 1 1 1 0 FAM83 A-H BSP_II PF05432.11 KPI44034.1 - 1.9 8.1 18.0 3.8 7.1 18.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 KPI44034.1 - 2.8 7.2 27.2 4.5 6.5 23.2 2.2 2 0 0 2 2 2 0 BUD22 DUF2418 PF10332.9 KPI44036.1 - 1.1e-32 112.4 0.2 2.5e-32 111.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) SIT PF15330.6 KPI44036.1 - 1.3 9.5 5.7 0.22 12.0 0.1 2.7 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT GDC-P PF02347.16 KPI44037.1 - 6.8e-176 585.3 0.0 4.2e-163 543.2 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KPI44037.1 - 3.2e-07 29.9 0.1 1.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase UNC-93 PF05978.16 KPI44038.1 - 1.7e-10 40.9 3.4 4.6e-10 39.4 3.4 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KPI44038.1 - 5.5e-09 35.4 14.0 5.5e-09 35.4 14.0 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M48_N PF16491.5 KPI44038.1 - 0.00011 22.2 1.0 0.18 11.7 0.1 2.8 2 1 0 2 2 2 2 CAAX prenyl protease N-terminal, five membrane helices Choline_kinase PF01633.20 KPI44039.1 - 7.9e-46 156.3 0.0 2.4e-43 148.2 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 KPI44039.1 - 6.4e-10 39.4 0.0 2.9e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KPI44039.1 - 0.0002 20.8 0.0 0.00039 19.8 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KPI44039.1 - 0.073 11.9 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fungal_trans PF04082.18 KPI44040.1 - 1.5e-07 30.7 0.2 3.3e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TruD PF01142.18 KPI44041.1 - 5.7e-61 206.6 0.3 2e-53 181.8 0.1 4.0 4 0 0 4 4 4 4 tRNA pseudouridine synthase D (TruD) RNA_pol_Rpc4 PF05132.14 KPI44041.1 - 6.7 7.1 6.2 29 5.1 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 GFO_IDH_MocA PF01408.22 KPI44042.1 - 8.3e-08 33.1 0.1 2.8e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_transf_3 PF02515.17 KPI44043.1 - 1.2e-33 116.8 0.3 2.6e-29 102.5 0.5 3.0 2 1 0 2 2 2 2 CoA-transferase family III Aldedh PF00171.22 KPI44044.1 - 5.9e-13 48.1 0.1 4.5e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 KPI44044.1 - 0.024 13.7 0.4 0.23 10.5 0.2 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Fungal_trans_2 PF11951.8 KPI44045.1 - 8e-05 21.6 3.5 0.0011 17.9 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain AAA PF00004.29 KPI44046.1 - 1.1e-86 288.0 0.0 2.9e-42 144.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI44046.1 - 5.9e-15 54.8 0.8 9.2e-07 28.6 0.2 3.0 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KPI44046.1 - 2.4e-13 50.1 0.0 4.4e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI44046.1 - 5.2e-13 49.7 3.8 0.00014 22.3 1.7 5.4 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KPI44046.1 - 1.1e-11 45.1 0.2 0.003 17.8 0.0 4.8 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 KPI44046.1 - 1.2e-09 38.5 0.0 0.0003 21.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KPI44046.1 - 1.7e-09 37.8 0.0 4.6e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KPI44046.1 - 3.8e-09 36.7 0.2 0.008 16.2 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KPI44046.1 - 5.7e-09 36.6 0.0 0.0004 20.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_2 PF07724.14 KPI44046.1 - 8.4e-09 35.8 0.0 0.0073 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KPI44046.1 - 1.7e-08 34.4 0.0 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 KPI44046.1 - 8.8e-08 32.8 0.0 0.024 15.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 KPI44046.1 - 9.9e-08 32.4 0.0 0.0038 17.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KPI44046.1 - 2.1e-07 30.5 0.1 0.00064 19.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KPI44046.1 - 2.9e-07 30.9 0.0 0.022 15.1 0.0 3.1 3 0 0 3 3 3 2 RNA helicase Rad17 PF03215.15 KPI44046.1 - 4.8e-07 29.9 0.0 0.0009 19.2 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain TsaE PF02367.17 KPI44046.1 - 1.4e-06 28.3 0.0 0.045 13.8 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KPI44046.1 - 1.7e-06 28.5 0.1 0.0025 18.2 0.0 3.1 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KPI44046.1 - 2.1e-06 27.1 0.3 0.087 12.0 0.0 3.6 4 0 0 4 4 3 1 NB-ARC domain AAA_25 PF13481.6 KPI44046.1 - 4e-06 26.5 0.2 1.2 8.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 KPI44046.1 - 4.1e-06 26.8 0.2 0.16 11.9 0.0 3.8 3 1 0 4 4 3 2 NACHT domain Mg_chelatase PF01078.21 KPI44046.1 - 5.5e-06 25.9 0.7 0.075 12.4 0.1 3.1 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KPI44046.1 - 1.1e-05 25.3 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 KPI44046.1 - 1.3e-05 25.0 0.1 0.41 10.3 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 KPI44046.1 - 1.6e-05 24.8 0.0 0.039 13.8 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KPI44046.1 - 2.2e-05 24.7 0.0 0.00047 20.4 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.17 KPI44046.1 - 7.7e-05 21.9 0.2 0.33 10.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KPI44046.1 - 7.7e-05 22.1 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_11 PF13086.6 KPI44046.1 - 9e-05 22.4 1.2 0.2 11.4 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 KPI44046.1 - 0.00019 21.0 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 KPI44046.1 - 0.00024 21.7 4.3 0.014 15.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 KPI44046.1 - 0.00024 21.3 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.6 KPI44046.1 - 0.00032 21.1 0.7 0.13 12.6 0.2 2.9 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KPI44046.1 - 0.00034 20.3 0.1 1.4 8.5 0.0 3.0 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.6 KPI44046.1 - 0.00048 20.3 0.0 0.36 10.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 KPI44046.1 - 0.00057 19.9 0.0 0.95 9.3 0.0 2.7 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KPI44046.1 - 0.00081 19.2 0.1 0.46 10.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KPI44046.1 - 0.00084 19.1 0.1 1.4 8.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KPI44046.1 - 0.0009 18.9 0.1 0.43 10.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain PhoH PF02562.16 KPI44046.1 - 0.001 18.6 0.5 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ADK PF00406.22 KPI44046.1 - 0.0011 19.1 0.1 0.21 11.7 0.0 2.9 3 0 0 3 3 2 1 Adenylate kinase ATPase PF06745.13 KPI44046.1 - 0.0035 16.7 0.3 2 7.7 0.0 3.0 2 1 0 3 3 3 1 KaiC Hydin_ADK PF17213.3 KPI44046.1 - 0.0038 17.5 0.0 0.0038 17.5 0.0 3.1 4 0 0 4 4 3 1 Hydin Adenylate kinase-like domain CPT PF07931.12 KPI44046.1 - 0.0068 16.3 0.0 0.56 10.0 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 KPI44046.1 - 0.0071 16.1 0.1 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase TniB PF05621.11 KPI44046.1 - 0.0076 15.7 0.0 2 7.8 0.0 3.5 2 1 1 3 3 3 1 Bacterial TniB protein NTPase_1 PF03266.15 KPI44046.1 - 0.01 15.8 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 KPI44046.1 - 0.019 14.2 0.0 0.87 8.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 KPI44046.1 - 0.022 14.6 0.2 13 5.5 0.0 3.3 3 1 0 3 3 3 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 KPI44046.1 - 0.025 14.6 0.1 6.8 6.8 0.0 3.4 2 1 1 3 3 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KPI44046.1 - 0.027 14.2 0.0 15 5.4 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Vps4_C PF09336.10 KPI44046.1 - 0.031 14.3 0.2 0.19 11.8 0.0 2.4 2 1 1 3 3 1 0 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KPI44046.1 - 0.032 13.4 0.0 3 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 KPI44046.1 - 0.05 12.7 0.1 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KPI44046.1 - 0.071 12.7 0.1 17 5.0 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nop PF01798.18 KPI44046.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin MSA-2c PF12238.8 KPI44046.1 - 0.43 10.5 3.5 1 9.4 3.5 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Fungal_trans_2 PF11951.8 KPI44047.1 - 3.6e-13 49.1 0.9 7.4e-13 48.1 0.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2374 PF09574.10 KPI44047.1 - 0.22 11.4 2.3 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) PTCB-BRCT PF12738.7 KPI44048.1 - 9e-38 128.1 3.4 8.1e-20 70.5 0.5 5.2 5 0 0 5 5 5 3 twin BRCT domain BRCT_2 PF16589.5 KPI44048.1 - 7.5e-36 122.4 0.0 6.6e-06 26.4 0.3 6.3 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KPI44048.1 - 1.1e-33 115.5 0.0 2.6e-10 40.5 0.2 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KPI44048.1 - 2.8e-33 113.8 0.3 2e-27 95.0 0.0 5.0 6 0 0 6 6 6 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KPI44048.1 - 5e-11 42.7 0.4 0.00071 19.8 0.0 4.0 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KPI44048.1 - 0.00064 19.7 2.1 6.4 6.9 0.1 4.8 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 KPI44048.1 - 0.014 15.8 0.0 8.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein TIM PF00121.18 KPI44049.1 - 5.2e-21 75.1 0.0 1.5e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Triosephosphate isomerase bZIP_1 PF00170.21 KPI44050.1 - 6.1e-07 29.4 13.9 9.5e-07 28.8 13.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KPI44050.1 - 0.02 15.4 12.7 0.04 14.4 12.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KPI44050.1 - 0.02 14.9 18.0 0.038 14.1 17.9 1.6 1 1 0 1 1 1 0 Basic region leucine zipper DUF3972 PF13118.6 KPI44050.1 - 0.072 13.5 2.2 0.11 12.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) SecA_DEAD PF07517.14 KPI44050.1 - 0.67 9.2 3.4 0.95 8.7 3.4 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain PQ-loop PF04193.14 KPI44051.1 - 3.7e-37 125.9 15.5 1.1e-19 69.9 0.7 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KPI44051.1 - 0.01 16.7 0.4 0.27 12.0 0.0 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor MtN3_slv PF03083.16 KPI44051.1 - 0.081 13.0 1.3 0.21 11.6 0.0 2.3 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange CobD_Cbib PF03186.13 KPI44051.1 - 0.12 11.5 0.7 0.18 11.0 0.5 1.4 1 1 0 1 1 1 0 CobD/Cbib protein Peptidase_M3 PF01432.20 KPI44052.1 - 1e-159 532.7 0.1 1.3e-159 532.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF1275 PF06912.11 KPI44053.1 - 2.2e-43 148.4 10.8 2.7e-43 148.1 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Mito_morph_reg PF14972.6 KPI44053.1 - 0.031 13.9 0.1 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator adh_short_C2 PF13561.6 KPI44054.1 - 7.8e-44 150.0 1.2 6.8e-31 107.6 0.4 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44054.1 - 8.3e-33 113.5 0.2 1.1e-32 113.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 KPI44054.1 - 0.0065 16.4 0.5 0.058 13.3 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2574 PF10836.8 KPI44056.1 - 2.2 8.2 9.3 1.5 8.7 5.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2574) Med16 PF11635.8 KPI44057.1 - 8.6e-22 76.9 0.0 1.2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Rhodanese PF00581.20 KPI44058.1 - 4.5e-11 43.2 0.0 6.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Glycos_transf_4 PF00953.21 KPI44061.1 - 1.4e-33 116.1 7.7 1.4e-33 116.1 7.7 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 RAC_head PF16717.5 KPI44062.1 - 9.6e-27 93.8 2.9 9.6e-27 93.8 2.9 3.0 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 KPI44062.1 - 1.2e-18 67.0 1.1 1.2e-18 67.0 1.1 2.3 2 0 0 2 2 2 1 DnaJ domain V_ATPase_I PF01496.19 KPI44062.1 - 6.8 4.5 11.6 12 3.6 11.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAD PF12710.7 KPI44063.1 - 1.3e-20 74.6 0.0 1.9e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI44063.1 - 3e-20 73.4 0.0 4.2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KPI44063.1 - 3.3e-11 43.4 0.0 5e-10 39.5 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPI44063.1 - 2.5e-06 27.7 0.0 0.024 14.7 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KPI44063.1 - 2e-05 24.1 0.0 0.00019 20.9 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.12 KPI44063.1 - 0.029 13.8 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF4287 PF14117.6 KPI44063.1 - 0.16 12.1 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) ADH_zinc_N PF00107.26 KPI44064.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI44064.1 - 3.6e-05 23.6 0.0 0.0005 19.9 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Beta-lactamase PF00144.24 KPI44065.1 - 4.3e-42 144.5 0.2 6.5e-42 143.9 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KPI44065.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase FMN_dh PF01070.18 KPI44066.1 - 2.6e-104 349.0 0.0 3e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KPI44066.1 - 6.1e-05 22.2 0.1 0.0001 21.4 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KPI44066.1 - 0.00011 21.4 0.2 0.00017 20.9 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KPI44066.1 - 0.002 17.6 0.7 0.13 11.7 0.1 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 KPI44066.1 - 0.031 13.7 0.6 0.05 13.0 0.6 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 KPI44066.1 - 0.036 13.4 1.1 8.7 5.6 0.1 2.8 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KPI44066.1 - 0.11 11.7 0.1 0.38 9.9 0.1 1.8 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Sugar_tr PF00083.24 KPI44067.1 - 1.6e-75 254.7 20.9 2.1e-75 254.4 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44067.1 - 1.7e-08 33.8 36.4 1.7e-08 33.8 36.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAT PF04768.13 KPI44068.1 - 1.5e-47 161.4 0.0 7.6e-46 155.9 0.0 2.9 4 0 0 4 4 4 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase EF-G-binding_N PF07299.11 KPI44068.1 - 0.15 12.6 0.3 3.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal GCP_C_terminal PF04130.13 KPI44069.1 - 9.7e-57 192.8 4.9 1.7e-56 191.9 4.9 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KPI44069.1 - 1e-45 156.7 0.0 9.6e-30 104.2 0.0 2.5 1 1 1 2 2 2 2 Gamma tubulin complex component N-terminal Trans_reg_C PF00486.28 KPI44069.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Coq4 PF05019.13 KPI44070.1 - 4.4e-97 323.8 0.0 5.4e-97 323.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MFS_1 PF07690.16 KPI44071.1 - 2.1e-31 109.1 26.4 2.1e-31 109.1 26.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KPI44071.1 - 3.5 7.5 6.9 11 5.9 0.0 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 KPI44071.1 - 4.5 7.1 11.1 0.13 12.0 0.3 3.3 2 1 2 4 4 4 0 Bacteriophage holin family, superfamily II-like FAD_binding_2 PF00890.24 KPI44072.1 - 1.3e-35 123.3 0.0 2.1e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 2OG-FeII_Oxy_2 PF13532.6 KPI44072.1 - 9.8e-12 45.5 0.1 2.2e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAO PF01266.24 KPI44072.1 - 0.034 13.7 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase HTH_32 PF13565.6 KPI44072.1 - 0.37 11.4 2.6 2.7 8.7 0.4 3.2 3 0 0 3 3 3 0 Homeodomain-like domain SNARE PF05739.19 KPI44073.1 - 2.3e-12 46.7 0.1 6.2e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KPI44073.1 - 2.6e-11 42.4 0.2 6.3e-11 41.2 0.2 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KPI44073.1 - 1.1e-05 25.2 5.0 0.00025 20.8 0.1 2.6 2 0 0 2 2 2 1 Syntaxin KxDL PF10241.9 KPI44073.1 - 0.0061 16.8 3.8 0.19 12.0 0.1 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein Prominin PF05478.11 KPI44073.1 - 0.073 11.0 3.4 2.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Prominin DUF4100 PF13352.6 KPI44073.1 - 0.075 12.8 1.7 0.14 11.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) DUF16 PF01519.16 KPI44073.1 - 0.077 13.5 0.5 0.077 13.5 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 ZYG-11_interact PF05884.12 KPI44073.1 - 0.16 11.3 0.7 0.34 10.3 0.7 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 RmuC PF02646.16 KPI44073.1 - 0.21 10.7 8.8 2.1 7.4 0.7 3.1 2 1 1 3 3 3 0 RmuC family Syntaxin-18_N PF10496.9 KPI44073.1 - 0.23 11.7 5.1 0.3 11.4 0.0 2.8 3 1 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.12 KPI44073.1 - 0.27 11.7 7.3 6.1 7.4 0.3 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.11 KPI44073.1 - 0.29 10.5 7.9 1.4 8.2 0.2 2.9 2 1 0 3 3 3 0 SF-assemblin/beta giardin DUF4988 PF16378.5 KPI44073.1 - 0.51 10.0 5.0 8.9 5.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function SKA1 PF07160.12 KPI44073.1 - 0.82 9.5 7.4 1.7 8.5 3.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 KPI44073.1 - 1.5 8.9 5.3 8.3 6.5 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KPI44073.1 - 2.8 8.3 6.8 2.9 8.2 0.1 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BCNT PF07572.12 KPI44074.1 - 1.5e-22 79.4 2.7 4.4e-22 77.9 0.7 2.3 2 0 0 2 2 2 1 Bucentaur or craniofacial development RCSD PF05177.12 KPI44074.1 - 1.2 10.0 11.4 0.21 12.5 6.8 2.2 2 0 0 2 2 2 0 RCSD region Amidohydro_2 PF04909.14 KPI44075.1 - 4.2e-27 95.7 0.0 5.1e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase BTB PF00651.31 KPI44076.1 - 2.7e-10 40.5 0.0 1e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Syntaxin_2 PF14523.6 KPI44077.1 - 3.3e-25 88.4 7.1 3.9e-25 88.1 2.0 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KPI44077.1 - 1.1e-15 57.3 1.6 2.4e-15 56.2 1.6 1.6 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 KPI44077.1 - 0.0033 15.5 1.8 0.012 13.7 0.5 1.9 2 0 0 2 2 2 1 Prominin T3SSipB PF16535.5 KPI44077.1 - 0.01 16.3 2.1 0.019 15.5 2.1 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB Syntaxin PF00804.25 KPI44077.1 - 0.011 15.5 13.4 0.17 11.6 12.8 2.6 1 1 1 2 2 2 0 Syntaxin DUF883 PF05957.13 KPI44077.1 - 0.3 11.7 0.1 0.3 11.7 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF16 PF01519.16 KPI44077.1 - 2.5 8.6 9.7 1.7 9.1 0.5 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 adh_short_C2 PF13561.6 KPI44079.1 - 5.3e-54 183.3 0.0 6.3e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44079.1 - 1.5e-49 168.1 0.0 1.8e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI44079.1 - 4.9e-12 46.1 0.2 1e-11 45.1 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPI44079.1 - 1.7e-05 24.4 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI44079.1 - 0.00012 21.6 0.1 0.00021 20.8 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KPI44079.1 - 0.00022 21.2 0.3 0.00038 20.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_transf_5 PF08323.11 KPI44079.1 - 0.0083 15.9 0.0 0.48 10.1 0.0 2.3 2 1 1 3 3 3 1 Starch synthase catalytic domain RmlD_sub_bind PF04321.17 KPI44079.1 - 0.019 14.0 0.1 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 KPI44079.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KPI44079.1 - 0.034 13.7 0.3 0.054 13.1 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 KPI44079.1 - 0.066 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 KPI44079.1 - 0.097 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.17 KPI44079.1 - 0.097 13.3 0.6 1.2 9.8 0.2 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KPI44079.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.19 KPI44079.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 3HCDH_N PF02737.18 KPI44079.1 - 0.22 11.4 0.7 0.42 10.5 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AidB_N PF18158.1 KPI44080.1 - 4.7e-18 65.6 0.0 1.9e-17 63.6 0.0 2.1 2 1 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KPI44080.1 - 1.4e-16 61.1 0.2 9.9e-15 55.0 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI44080.1 - 3.8e-11 43.1 0.0 1.4e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI44080.1 - 0.011 16.0 0.2 0.16 12.3 0.0 2.9 4 0 0 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain EGF_2 PF07974.13 KPI44082.1 - 6.3 7.3 10.8 12 6.4 10.8 1.5 1 0 0 1 1 1 0 EGF-like domain Glyoxalase_4 PF13669.6 KPI44083.1 - 9.6e-21 74.1 0.0 2.1e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KPI44084.1 - 4.2e-13 49.3 0.0 2.7e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI44084.1 - 9.4e-08 31.6 0.2 3e-05 23.4 0.6 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI44084.1 - 1.4e-05 24.4 2.1 2.4e-05 23.6 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI44084.1 - 2.1e-05 24.7 0.3 5.9e-05 23.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI44084.1 - 2.3e-05 24.2 2.1 8.2e-05 22.3 1.9 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI44084.1 - 7.8e-05 21.9 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KPI44084.1 - 0.001 18.0 0.0 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KPI44084.1 - 0.0021 18.6 1.3 0.016 15.8 2.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI44084.1 - 0.006 15.9 0.4 0.0085 15.4 0.4 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KPI44084.1 - 0.0087 15.2 0.9 0.012 14.7 0.9 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPI44084.1 - 0.0092 14.7 0.2 0.025 13.3 0.7 1.4 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.18 KPI44084.1 - 0.02 14.8 1.0 0.091 12.6 0.8 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KPI44084.1 - 0.02 14.9 2.8 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI44084.1 - 0.1 11.9 1.1 0.16 11.2 1.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI44084.1 - 0.14 11.4 0.1 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KPI44084.1 - 0.17 11.2 0.7 0.29 10.4 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KPI44084.1 - 0.26 10.8 0.2 0.4 10.2 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mito_carr PF00153.27 KPI44085.1 - 2.8e-65 216.3 4.5 1e-23 83.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clr5 PF14420.6 KPI44086.1 - 1e-14 54.5 1.5 2.8e-14 53.1 1.4 1.8 2 0 0 2 2 2 1 Clr5 domain Actin PF00022.19 KPI44088.1 - 2e-18 66.2 0.0 1.7e-14 53.2 0.0 2.6 3 0 0 3 3 3 2 Actin BRO1 PF03097.18 KPI44089.1 - 5e-119 397.6 1.1 5e-119 397.6 1.1 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KPI44089.1 - 4.9e-75 252.6 15.8 4.9e-75 252.6 15.8 2.3 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV LXG PF04740.12 KPI44089.1 - 0.25 11.1 3.3 0.77 9.4 0.0 3.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily Sec8_exocyst PF04048.14 KPI44089.1 - 0.36 10.7 3.1 1.9 8.4 0.3 3.2 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2237 PF09996.9 KPI44090.1 - 2.2e-39 134.0 0.1 2.8e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) p450 PF00067.22 KPI44091.1 - 1.2e-68 232.0 0.0 1.5e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase_3 PF07732.15 KPI44094.1 - 6.5e-41 139.1 0.9 1e-38 132.0 0.1 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KPI44094.1 - 1.3e-25 89.7 4.8 9.9e-18 64.2 0.1 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KPI44094.1 - 5.2e-16 59.2 0.0 4.7e-14 52.8 0.0 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KPI44094.1 - 0.015 15.4 0.0 4 7.6 0.0 3.9 3 1 1 4 4 4 0 Cupredoxin-like domain Sugar_tr PF00083.24 KPI44096.1 - 6.5e-47 160.4 6.9 8.1e-47 160.1 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44096.1 - 4.6e-13 48.8 24.0 9.1e-13 47.8 23.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI44096.1 - 0.098 11.1 4.7 0.065 11.6 2.6 1.7 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) SPX PF03105.19 KPI44097.1 - 0.093 12.6 4.1 0.12 12.3 4.1 1.0 1 0 0 1 1 1 0 SPX domain SMC_N PF02463.19 KPI44098.1 - 1.6e-68 230.4 7.5 2.1e-67 226.8 7.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPI44098.1 - 1.8e-21 76.6 1.5 9.1e-20 71.1 0.2 3.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KPI44098.1 - 4.4e-09 36.6 7.6 0.00014 21.8 0.2 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPI44098.1 - 0.00054 19.7 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 KPI44098.1 - 0.00089 18.7 8.5 0.00089 18.7 8.5 7.2 3 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 KPI44098.1 - 0.028 14.9 0.0 0.028 14.9 0.0 5.7 4 2 1 5 5 5 0 ABC transporter Surface_Ag_2 PF01617.17 KPI44098.1 - 1.2 8.6 3.5 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Surface antigen HSBP1 PF06825.12 KPI44098.1 - 6.5 6.7 14.2 1.2 9.1 0.6 5.4 7 0 0 7 7 7 0 Heat shock factor binding protein 1 BPL_LplA_LipB PF03099.19 KPI44099.1 - 5.1e-07 29.6 0.0 9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Eno-Rase_FAD_bd PF07055.12 KPI44099.1 - 0.076 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain p450 PF00067.22 KPI44100.1 - 6.4e-78 262.5 0.0 8.8e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 KPI44100.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain PXA PF02194.15 KPI44101.1 - 7.1e-46 156.5 1.2 1.3e-45 155.6 1.2 1.4 1 0 0 1 1 1 1 PXA domain RGS PF00615.19 KPI44101.1 - 1e-11 45.1 0.0 2.9e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain RRP36 PF06102.12 KPI44101.1 - 0.025 14.5 0.1 0.062 13.3 0.1 1.6 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Pkinase PF00069.25 KPI44103.1 - 1.5e-06 27.8 0.0 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44103.1 - 7.5e-06 25.4 0.0 9.7e-05 21.8 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase p450 PF00067.22 KPI44104.1 - 5.7e-59 200.1 0.0 7.9e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KPI44105.1 - 1.9e-24 86.6 0.1 3e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI44105.1 - 0.0007 19.3 0.6 0.019 14.6 0.0 2.5 1 1 1 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPI44105.1 - 0.017 14.0 0.2 7.8 5.2 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KPI44105.1 - 0.058 12.6 0.1 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI44105.1 - 0.077 13.2 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI44105.1 - 0.077 13.6 0.1 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BP28CT PF08146.12 KPI44107.1 - 3.4e-34 118.0 2.6 7.2e-34 116.9 0.4 2.9 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KPI44107.1 - 4.6e-08 33.4 0.4 4.6e-08 33.4 0.4 4.1 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 Cnd1 PF12717.7 KPI44107.1 - 0.21 11.6 3.9 1.9 8.5 0.0 4.3 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Chorismate_synt PF01264.21 KPI44108.1 - 3.8e-139 463.0 0.0 4.4e-139 462.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.17 KPI44108.1 - 0.41 10.7 2.1 1.1 9.4 2.1 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Glyoxalase PF00903.25 KPI44109.1 - 8.2e-10 39.0 1.9 8.7e-09 35.7 0.5 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPI44109.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KPI44110.1 - 7.9e-18 64.4 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI44110.1 - 0.00034 20.7 10.1 0.00051 20.1 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WH2 PF02205.20 KPI44111.1 - 5.5e-07 29.2 0.9 5.5e-07 29.2 0.9 2.0 2 0 0 2 2 2 1 WH2 motif Trefoil PF00088.18 KPI44111.1 - 0.72 9.8 3.0 25 4.8 0.5 2.4 2 0 0 2 2 2 0 Trefoil (P-type) domain SPRY PF00622.28 KPI44112.1 - 0.13 12.4 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 SPRY domain Abhydrolase_6 PF12697.7 KPI44113.1 - 5.3e-09 37.0 1.0 7.2e-09 36.6 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI44113.1 - 2.6e-06 26.9 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI44113.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1989 PF09347.10 KPI44115.1 - 9e-44 149.0 0.1 2.1e-38 131.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) Rad4 PF03835.15 KPI44116.1 - 8.4e-32 109.9 0.1 5.3e-31 107.3 0.1 2.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KPI44116.1 - 3.7e-14 52.3 0.0 1.2e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 KPI44116.1 - 6.5e-14 52.1 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KPI44116.1 - 1.2e-13 51.7 0.4 1.2e-13 51.7 0.4 4.6 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KPI44116.1 - 0.0014 19.0 0.0 0.0059 17.0 0.0 2.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily HpcH_HpaI PF03328.14 KPI44117.1 - 5.7e-33 113.9 0.0 7.8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family NCD3G PF07562.14 KPI44117.1 - 0.23 11.5 1.1 0.41 10.7 0.6 1.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR RFamide_26RFa PF11109.8 KPI44118.1 - 0.1 13.1 1.5 0.17 12.4 0.0 2.1 3 0 0 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 HECT PF00632.25 KPI44119.1 - 4.1e-84 282.7 0.0 3.1e-78 263.4 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.26 KPI44119.1 - 1.6e-33 114.5 19.4 1.1e-11 44.5 1.4 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KPI44119.1 - 5.3e-19 68.4 0.0 1.6e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain GGDEF PF00990.21 KPI44119.1 - 0.0085 15.9 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain NmrA PF05368.13 KPI44120.1 - 2.1e-08 34.0 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI44120.1 - 2.8e-06 27.4 0.0 6.1e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI44120.1 - 0.012 15.9 0.0 0.034 14.4 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KPI44120.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2231 PF09990.9 KPI44121.1 - 4.4e-06 27.1 0.2 7.8e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) PEN-2 PF10251.9 KPI44121.1 - 0.052 14.0 0.9 5.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase RhoGEF PF00621.20 KPI44122.1 - 4.1e-25 89.1 0.0 6.4e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FCP1_C PF09309.10 KPI44122.1 - 0.0006 19.8 1.2 0.0013 18.7 1.2 1.5 1 0 0 1 1 1 1 FCP1, C-terminal BTB PF00651.31 KPI44123.1 - 1.5e-13 50.9 0.1 3.7e-13 49.7 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Utp21 PF04192.12 KPI44124.1 - 8.6e-46 156.3 0.0 1.5e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KPI44124.1 - 2.6e-17 62.9 0.0 0.00037 20.7 0.0 5.9 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI44124.1 - 5.8e-15 55.4 16.8 0.00028 21.6 0.2 10.0 10 1 0 10 10 10 4 WD domain, G-beta repeat eIF2A PF08662.11 KPI44124.1 - 0.035 14.0 0.0 2.2 8.1 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KPI44124.1 - 0.062 13.3 0.5 59 3.8 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat VID27 PF08553.10 KPI44124.1 - 0.15 11.1 0.0 6.4 5.7 0.0 3.1 3 1 1 4 4 4 0 VID27 C-terminal WD40-like domain Med16 PF11635.8 KPI44126.1 - 3.4e-10 38.5 0.0 4.1e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 PWI PF01480.17 KPI44127.1 - 2.7e-14 53.2 0.3 5.6e-14 52.2 0.1 1.7 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 KPI44127.1 - 0.0024 17.7 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pribosyltran PF00156.27 KPI44128.1 - 1.6e-16 60.2 0.1 2.3e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KPI44128.1 - 0.015 14.8 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase NDUF_B8 PF05821.11 KPI44129.1 - 1.9e-10 40.9 0.1 2.2e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Abhydrolase_1 PF00561.20 KPI44131.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44131.1 - 3.8e-06 27.7 0.1 5.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI44131.1 - 0.00067 19.0 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KPI44131.1 - 0.0044 15.8 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family U-box PF04564.15 KPI44132.1 - 7.6e-23 80.5 0.0 4.7e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 U-box domain TPR_1 PF00515.28 KPI44132.1 - 8.6e-10 38.0 3.0 0.0011 18.7 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI44132.1 - 1.2e-09 37.6 6.1 0.0072 16.4 0.1 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KPI44132.1 - 2.2e-06 28.2 5.1 0.0017 19.0 2.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KPI44132.1 - 9.7e-06 25.8 3.7 0.075 13.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI44132.1 - 0.00082 19.6 1.3 0.22 11.7 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KPI44132.1 - 0.011 15.9 2.9 6.9 7.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 KPI44132.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_10 PF13374.6 KPI44132.1 - 0.051 13.5 4.4 1.2 9.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KPI44132.1 - 0.054 13.5 5.3 1.4 9.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KPI44132.1 - 0.11 13.3 11.9 1.6 9.8 0.0 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 KPI44133.1 - 2.4e-127 426.2 5.4 2.4e-127 426.2 5.4 1.5 1 1 1 2 2 2 1 Nucleoporin protein Ndc1-Nup RNR_inhib PF08591.10 KPI44134.1 - 1.7e-13 51.8 1.0 7.3e-13 49.8 0.0 2.2 1 1 1 2 2 2 1 Ribonucleotide reductase inhibitor TSA PF03249.13 KPI44134.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen HemY_N PF07219.13 KPI44135.1 - 0.012 15.8 1.7 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Neur_chan_memb PF02932.16 KPI44135.1 - 0.35 10.9 1.5 7.1 6.6 0.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PIG-L PF02585.17 KPI44136.1 - 1.5e-09 38.6 0.0 2.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cys_Met_Meta_PP PF01053.20 KPI44137.1 - 9.1e-138 458.9 0.0 1.1e-137 458.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPI44137.1 - 3.5e-06 26.4 0.0 6.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI44137.1 - 2.1e-05 23.7 0.1 4.1e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPI44137.1 - 4.6e-05 22.9 0.1 0.0002 20.8 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KPI44137.1 - 0.00013 20.6 0.0 0.00093 17.8 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KPI44137.1 - 0.024 13.9 0.0 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase SelA PF03841.13 KPI44137.1 - 0.037 13.0 0.1 0.11 11.5 0.1 1.7 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Sec2p PF06428.11 KPI44138.1 - 4.8e-25 87.4 14.0 4.8e-25 87.4 14.0 2.8 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF5339 PF17274.2 KPI44138.1 - 0.00057 20.7 7.4 0.087 13.7 0.3 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5339) DUF1366 PF07104.11 KPI44138.1 - 0.4 10.4 8.4 2.4 7.9 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) DUF3584 PF12128.8 KPI44138.1 - 0.65 7.4 21.7 1 6.8 21.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CASP_C PF08172.12 KPI44138.1 - 1.1 8.5 17.8 0.6 9.4 14.2 2.1 2 0 0 2 2 2 0 CASP C terminal Csm1_N PF18504.1 KPI44138.1 - 1.5 9.2 10.7 0.05 13.9 1.2 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain Prominin PF05478.11 KPI44138.1 - 1.9 6.3 5.5 2.8 5.8 5.5 1.1 1 0 0 1 1 1 0 Prominin GCN5L1 PF06320.13 KPI44138.1 - 8.4 6.6 14.3 0.59 10.3 5.1 3.1 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Oxysterol_BP PF01237.18 KPI44139.1 - 2.7e-52 177.8 0.0 6.6e-50 170.0 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein adh_short PF00106.25 KPI44140.1 - 2.9e-39 134.6 0.0 3.8e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44140.1 - 8e-26 91.0 0.0 1.3e-25 90.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44140.1 - 3e-09 37.0 0.0 4.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KPI44140.1 - 0.00047 19.9 0.1 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 KPI44140.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KPI44140.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CoA_binding_2 PF13380.6 KPI44140.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Pyr_redox_2 PF07992.14 KPI44141.1 - 2.5e-27 95.9 0.0 2.8e-23 82.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI44141.1 - 3.2e-10 40.4 0.0 4.5e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI44141.1 - 0.0065 16.7 0.0 3.9 7.8 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Abhydrolase_6 PF12697.7 KPI44141.1 - 0.049 14.2 0.2 0.1 13.2 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FMN_dh PF01070.18 KPI44143.1 - 6.1e-114 380.7 0.0 7.5e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KPI44143.1 - 0.0032 16.5 0.6 0.0061 15.6 0.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KPI44143.1 - 0.0063 15.9 2.3 0.0095 15.4 2.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KPI44143.1 - 0.0077 15.4 0.1 0.012 14.8 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KPI44143.1 - 0.013 14.9 0.9 2.8 7.2 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KPI44143.1 - 0.055 12.9 0.3 1.9 7.9 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein NAD_binding_2 PF03446.15 KPI44145.1 - 3.9e-33 114.8 0.1 7.6e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPI44145.1 - 4.2e-12 46.5 0.1 5.4e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 KPI44145.1 - 7.3e-12 45.6 0.3 1.2e-11 44.9 0.3 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KPI44145.1 - 4.9e-10 39.6 0.2 2.2e-09 37.5 0.0 2.0 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KPI44145.1 - 0.0045 17.3 0.9 0.014 15.6 0.1 2.3 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain zinc_ribbon_11 PF11682.8 KPI44145.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon GFO_IDH_MocA PF01408.22 KPI44145.1 - 0.03 15.2 0.0 0.095 13.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 KPI44145.1 - 0.069 12.7 0.2 0.61 9.6 0.1 2.4 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 KPI44145.1 - 0.089 12.7 0.6 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H-binding EF-hand_7 PF13499.6 KPI44146.1 - 1.6e-12 47.7 0.8 2.8e-07 30.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KPI44146.1 - 1.2e-10 40.4 0.7 0.00028 20.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KPI44146.1 - 1.9e-10 39.5 0.3 0.00049 19.5 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KPI44146.1 - 3.2e-10 40.2 0.0 0.00016 21.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KPI44146.1 - 6.5e-09 35.5 0.3 7.4e-05 22.5 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair DUF3216 PF11505.8 KPI44146.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Pkinase PF00069.25 KPI44147.1 - 5.2e-51 173.5 0.0 8.4e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44147.1 - 4.2e-25 88.5 0.0 3.3e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KPI44147.1 - 0.014 15.3 0.1 6.2 6.7 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KPI44147.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EBP50_C PF09007.11 KPI44147.1 - 0.67 11.0 9.8 0.059 14.4 3.6 2.2 2 0 0 2 2 2 0 EBP50, C-terminal IKI3 PF04762.12 KPI44149.1 - 3.8e-164 548.1 0.0 5e-164 547.7 0.0 1.1 1 0 0 1 1 1 1 IKI3 family TPR_14 PF13428.6 KPI44149.1 - 0.43 11.5 3.5 20 6.4 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 KPI44150.1 - 2.7e-14 53.1 0.0 4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_3 PF13738.6 KPI44152.1 - 6.2e-12 45.4 0.0 1.4e-11 44.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI44152.1 - 6.2e-11 41.4 0.0 2e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KPI44152.1 - 8.3e-11 41.7 0.0 2.7e-09 36.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI44152.1 - 5.1e-10 39.0 0.0 5.3e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI44152.1 - 1.2e-08 35.1 0.3 1.5e-06 28.3 0.0 3.2 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI44152.1 - 1.7e-08 34.4 0.6 0.0014 18.3 0.2 4.0 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KPI44152.1 - 7.3e-06 25.4 0.1 4.3e-05 22.9 0.0 2.2 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 KPI44152.1 - 1.4e-05 25.5 0.0 0.094 13.3 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI44152.1 - 0.004 16.3 0.2 0.026 13.6 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KPI44152.1 - 0.0071 15.5 0.4 2.8 6.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.20 KPI44152.1 - 0.016 15.3 0.0 0.5 10.4 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KPI44152.1 - 0.029 14.4 1.0 3.2 7.7 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI44152.1 - 0.048 12.7 0.2 0.68 8.9 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 KPI44152.1 - 0.15 10.7 0.6 1.9 7.1 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 KPI44152.1 - 0.17 12.3 0.0 0.72 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.15 KPI44152.1 - 0.22 10.0 0.0 8.3 4.8 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) RPE65 PF03055.15 KPI44153.1 - 6.2e-110 368.5 0.0 7.7e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein His_Phos_2 PF00328.22 KPI44155.1 - 1.6e-90 304.2 0.0 9.6e-89 298.4 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KPI44155.1 - 7.1e-36 122.2 0.0 1.4e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KPI44155.1 - 4.9e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Acetyltransf_1 PF00583.25 KPI44157.1 - 4.8e-07 30.0 0.0 1.1e-06 28.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KPI44157.1 - 1.7e-06 27.9 0.0 4.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KPI44157.1 - 6e-06 26.2 0.1 1.2e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI44157.1 - 6.3e-06 26.5 0.0 9.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI44157.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KPI44157.1 - 0.023 15.4 0.0 0.033 14.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribonuc_L-PSP PF01042.21 KPI44158.1 - 2.1e-37 127.8 0.0 3.6e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_3 PF01494.19 KPI44158.1 - 4.5e-11 42.6 1.4 3.2e-10 39.8 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI44158.1 - 0.00097 18.4 0.1 0.014 14.7 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPI44158.1 - 0.0011 18.1 0.0 0.0079 15.3 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DUF202 PF02656.15 KPI44159.1 - 1.3e-15 57.6 4.5 5.3e-15 55.6 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ADH_zinc_N PF00107.26 KPI44160.1 - 1.6e-28 99.2 0.1 2.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI44160.1 - 4.3e-10 40.8 0.0 6.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI44160.1 - 2.1e-05 24.3 0.0 0.00012 21.9 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KPI44160.1 - 0.0029 16.9 0.1 0.0045 16.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPI44160.1 - 0.19 11.0 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3425 PF11905.8 KPI44162.1 - 5e-11 42.7 0.3 1e-10 41.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI44162.1 - 0.0024 17.9 17.0 0.0091 16.1 17.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KPI44162.1 - 0.045 14.4 1.0 0.084 13.5 1.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Chibby PF14645.6 KPI44162.1 - 0.052 14.0 2.1 0.11 12.9 2.1 1.5 1 0 0 1 1 1 0 Chibby family BMFP PF04380.13 KPI44162.1 - 0.059 13.9 7.1 0.11 13.0 7.1 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity BBS2_C PF14782.6 KPI44162.1 - 0.071 11.9 0.2 0.096 11.4 0.2 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PRKG1_interact PF15898.5 KPI44162.1 - 0.13 13.2 8.0 0.25 12.3 8.0 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TipAS PF07739.13 KPI44162.1 - 0.29 11.7 3.7 0.56 10.8 3.7 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain NOC3p PF07540.11 KPI44162.1 - 0.36 11.3 2.6 0.38 11.3 0.1 2.1 2 0 0 2 2 2 0 Nucleolar complex-associated protein bZIP_2 PF07716.15 KPI44162.1 - 0.6 10.2 21.5 2.4e+02 1.9 21.5 2.3 1 1 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KPI44162.1 - 0.76 9.6 4.7 1.2 9.0 4.0 1.7 1 1 0 1 1 1 0 Septum formation initiator PikAIV_N PF18605.1 KPI44162.1 - 2.1 8.0 8.8 0.8 9.3 4.3 2.5 2 1 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF2937 PF11157.8 KPI44162.1 - 2.8 7.6 5.3 4.6 6.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TauD PF02668.16 KPI44163.1 - 4.8e-38 131.5 0.1 6.8e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transgly PF00912.22 KPI44163.1 - 0.13 11.7 0.1 0.42 10.0 0.1 1.7 2 0 0 2 2 2 0 Transglycosylase Anoctamin PF04547.12 KPI44164.1 - 3.3e-107 359.1 1.1 3.9e-107 358.9 1.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Aconitase PF00330.20 KPI44165.1 - 8.6e-145 483.2 0.0 1.1e-144 482.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KPI44165.1 - 5.3e-40 136.8 0.0 8.6e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_6 PF12697.7 KPI44166.1 - 2.8e-09 37.9 0.2 2e-07 31.9 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI44166.1 - 4.3e-06 26.6 0.0 1.7e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI44166.1 - 0.00017 20.9 0.3 0.00087 18.6 0.2 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Relaxase PF03432.14 KPI44166.1 - 0.0028 17.3 1.2 0.0033 17.1 1.2 1.1 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain Palm_thioest PF02089.15 KPI44166.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 KPI44166.1 - 0.011 15.6 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase CoA_binding_2 PF13380.6 KPI44167.1 - 2.5e-09 37.6 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain DUF4430 PF14478.6 KPI44167.1 - 0.046 14.3 0.2 0.096 13.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) Complex1_LYR PF05347.15 KPI44168.1 - 0.00018 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPI44168.1 - 0.038 14.7 0.0 0.043 14.6 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Peptidase_M49 PF03571.15 KPI44169.1 - 8.5e-245 813.3 0.0 1.1e-244 813.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 MFS_1 PF07690.16 KPI44170.1 - 7.4e-30 104.1 36.7 1.4e-22 80.1 17.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44170.1 - 7e-11 41.7 12.2 7e-11 41.7 12.2 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPI44170.1 - 0.0014 17.1 3.8 0.0014 17.1 3.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ESCRT-II PF05871.12 KPI44171.1 - 3.2e-50 170.0 0.0 5e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit ADC PF06314.11 KPI44173.1 - 6.2e-14 52.1 0.0 7.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) ABC1 PF03109.16 KPI44174.1 - 1.2e-21 77.1 0.0 2.2e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 ABC1 family Raf1_HTH PF18579.1 KPI44174.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain Nexin_C PF08628.12 KPI44175.1 - 3.2e-24 85.7 0.1 9.7e-24 84.1 0.0 1.9 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KPI44175.1 - 4.5e-21 75.0 0.6 4.5e-21 75.0 0.6 1.8 2 0 0 2 2 2 1 PX domain AIM3 PF17096.5 KPI44176.1 - 0.013 16.4 0.0 0.013 16.4 0.0 5.0 5 1 0 5 5 5 0 Altered inheritance of mitochondria protein 3 Macoilin PF09726.9 KPI44176.1 - 8.5 4.8 8.5 10 4.5 8.5 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KPI44177.1 - 1.8e-62 211.3 62.0 5.3e-40 137.4 5.3 3.8 2 1 1 4 4 4 4 Major Facilitator Superfamily OATP PF03137.20 KPI44177.1 - 4.4e-06 25.3 9.2 0.0017 16.8 2.3 3.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KPI44177.1 - 0.0044 16.4 46.8 0.0067 15.8 20.6 3.9 3 2 1 4 4 4 2 Uncharacterised MFS-type transporter YbfB PHD PF00628.29 KPI44178.1 - 0.00047 20.0 6.3 0.0009 19.1 6.3 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KPI44178.1 - 0.0013 19.3 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding BTB PF00651.31 KPI44180.1 - 2e-07 31.2 0.0 3.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Nop PF01798.18 KPI44181.1 - 2e-86 289.2 0.1 2e-86 289.2 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KPI44181.1 - 4e-18 65.6 0.0 4e-18 65.6 0.0 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DMT_YdcZ PF04657.13 KPI44181.1 - 0.054 13.8 0.1 0.099 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ DUF4746 PF15928.5 KPI44181.1 - 2.3 7.6 14.6 3.2 7.1 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Cytomega_UL84 PF06284.11 KPI44181.1 - 4.8 5.5 10.7 7.6 4.9 10.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CobT PF06213.12 KPI44181.1 - 7.1 5.9 18.6 7 6.0 16.4 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DTHCT PF08070.11 KPI44182.1 - 0.11 13.3 31.6 0.12 13.1 9.9 2.7 2 1 1 3 3 3 0 DTHCT (NUC029) region Fungal_trans_2 PF11951.8 KPI44183.1 - 4.7e-25 88.2 1.5 3.9e-20 72.0 0.5 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Bys1 PF04681.12 KPI44184.1 - 3.7e-06 26.9 2.8 7.8e-06 25.9 2.8 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein LRR_4 PF12799.7 KPI44186.1 - 2.1e-35 120.1 57.8 6.9e-09 35.8 0.8 6.3 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI44186.1 - 9e-22 76.6 34.1 1.1e-06 28.3 9.7 5.4 1 1 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KPI44186.1 - 1.5e-17 63.6 15.0 7.2e-08 32.1 2.9 3.4 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KPI44186.1 - 8.9e-05 22.3 29.2 0.52 10.5 0.2 8.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 KPI44186.1 - 0.00043 20.4 27.3 1.7 9.5 0.1 8.3 9 0 0 9 9 9 2 Leucine Rich Repeat Phage_rep_org_N PF09681.10 KPI44186.1 - 0.046 13.7 0.8 2.4 8.1 0.1 2.5 1 1 1 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) UB2H PF14814.6 KPI44186.1 - 0.21 11.7 1.2 8.7 6.5 0.0 3.8 1 1 3 5 5 5 0 Bifunctional transglycosylase second domain PHD PF00628.29 KPI44187.1 - 4.2e-08 33.0 10.8 1e-07 31.7 10.7 1.8 1 1 1 2 2 2 1 PHD-finger PHD_2 PF13831.6 KPI44187.1 - 0.2 11.2 11.6 0.013 15.0 6.0 1.9 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 KPI44187.1 - 1.6 9.1 7.6 0.26 11.6 2.7 2.0 2 0 0 2 2 2 0 C1 domain N2227 PF07942.12 KPI44188.1 - 2.9e-23 82.4 0.0 4.1e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Aminotran_5 PF00266.19 KPI44189.1 - 6.2e-28 97.8 0.0 7.9e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Tim44 PF04280.15 KPI44190.1 - 7.4e-27 94.3 0.0 1.3e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain Glyco_hydro_46 PF01374.18 KPI44190.1 - 0.13 11.9 0.5 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 46 MFS_1 PF07690.16 KPI44191.1 - 1.6e-39 135.8 32.9 2.5e-39 135.2 32.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM237 PF15383.6 KPI44191.1 - 0.0092 15.1 0.7 0.0092 15.1 0.7 1.9 2 0 0 2 2 2 1 Transmembrane protein 237 Abhydrolase_6 PF12697.7 KPI44192.1 - 7e-10 39.9 11.5 1.2e-09 39.2 11.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI44192.1 - 2.4e-07 30.7 0.2 4.1e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KPI44192.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF5610 PF18433.1 KPI44192.1 - 0.17 12.4 0.1 0.26 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) Ribonuc_L-PSP PF01042.21 KPI44193.1 - 7.6e-08 32.4 0.1 1.2e-07 31.8 0.1 1.4 1 1 0 1 1 1 1 Endoribonuclease L-PSP Ferric_reduct PF01794.19 KPI44194.1 - 3.3e-23 82.1 8.4 3.3e-23 82.1 8.4 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPI44194.1 - 1.6e-12 47.9 0.0 7.7e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI44194.1 - 8.6e-10 38.7 0.0 1.4e-05 25.2 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain DDE_Tnp_1 PF01609.21 KPI44194.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain NAD_binding_1 PF00175.21 KPI44194.1 - 0.076 13.7 0.0 0.19 12.4 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain HEAT PF02985.22 KPI44195.1 - 0.09 13.1 0.1 9.4 6.8 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat DAO PF01266.24 KPI44196.1 - 6.8e-38 131.2 0.0 8.5e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI44196.1 - 0.00042 20.5 0.1 0.0014 18.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI44196.1 - 0.002 18.6 0.0 0.4 11.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI44196.1 - 0.036 14.0 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KPI44196.1 - 0.15 11.2 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S10 PF00450.22 KPI44197.1 - 1.7e-87 294.5 0.7 2.2e-87 294.2 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase HMG_box PF00505.19 KPI44198.1 - 2.9e-14 53.2 0.5 4.9e-14 52.5 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KPI44198.1 - 0.1 13.2 0.2 0.19 12.3 0.2 1.5 1 0 0 1 1 1 0 HMG-box domain Cytadhesin_P30 PF07271.11 KPI44198.1 - 0.19 11.2 11.2 0.39 10.3 11.2 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 MFS_1 PF07690.16 KPI44200.1 - 2.9e-36 125.1 20.6 2.9e-36 125.1 20.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KPI44200.1 - 6.7 6.3 8.2 19 4.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Glypican PF01153.19 KPI44201.1 - 5.1 5.8 7.7 0.4 9.5 1.8 1.8 1 1 1 2 2 2 0 Glypican Glyco_transf_28 PF03033.20 KPI44202.1 - 2.6e-13 50.2 0.1 4.4e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Ras PF00071.22 KPI44203.1 - 2.5e-57 193.0 0.0 3.2e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI44203.1 - 3.5e-34 117.6 0.0 5.7e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI44203.1 - 5.7e-14 52.0 0.0 2.2e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI44203.1 - 1.7e-06 27.7 0.0 2.7e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI44203.1 - 9.7e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPI44203.1 - 6.4e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI44203.1 - 0.0031 17.4 0.2 2 8.3 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KPI44203.1 - 0.017 15.5 0.6 0.034 14.5 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATG_C PF09333.11 KPI44203.1 - 0.029 14.7 0.1 0.057 13.8 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain AAA_22 PF13401.6 KPI44203.1 - 0.11 12.7 0.0 1.2 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 KPI44203.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein VPS13_C PF16909.5 KPI44204.1 - 4.3e-06 26.6 0.4 8.4e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KPI44204.1 - 0.0022 18.3 0.0 0.17 12.3 0.0 3.2 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KPI44204.1 - 0.017 14.0 0.2 0.029 13.2 0.2 1.4 1 1 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KPI44204.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Helicase_C_3 PF13625.6 KPI44204.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Mito_carr PF00153.27 KPI44205.1 - 3.2e-67 222.5 6.2 1e-24 86.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PsbR PF04725.12 KPI44205.1 - 0.52 10.7 3.6 24 5.3 0.0 3.1 4 0 0 4 4 4 0 Photosystem II 10 kDa polypeptide PsbR Sulfotransfer_4 PF17784.1 KPI44207.1 - 1.6e-64 217.7 0.0 1.9e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI44207.1 - 0.0053 17.2 0.0 0.022 15.1 0.0 2.0 1 1 0 2 2 2 1 Sulfotransferase family MFS_1 PF07690.16 KPI44209.1 - 9.9e-15 54.3 42.5 6.5e-08 31.9 14.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SprT-like PF10263.9 KPI44210.1 - 1.5e-24 86.0 0.0 2.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KPI44210.1 - 6.2e-06 26.0 0.8 6.2e-06 26.0 0.8 2.4 2 0 0 2 2 2 1 SprT-like zinc ribbon domain PPV_E1_N PF00524.18 KPI44210.1 - 0.00043 20.7 5.5 0.0011 19.4 3.1 2.5 1 1 1 2 2 2 1 E1 Protein, N terminal domain SPT6_acidic PF14632.6 KPI44210.1 - 0.018 15.6 5.5 0.07 13.7 5.5 2.0 1 0 0 1 1 1 0 Acidic N-terminal SPT6 AA_permease PF00324.21 KPI44211.1 - 2.1e-108 363.0 40.4 6.1e-87 292.2 25.2 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KPI44211.1 - 1e-25 90.5 31.5 1.8e-22 79.8 23.5 2.0 1 1 1 2 2 2 2 Amino acid permease Colipase-like PF15083.6 KPI44213.1 - 0.26 11.4 3.5 0.37 10.9 3.5 1.2 1 0 0 1 1 1 0 Colipase-like TMEM40 PF15817.5 KPI44214.1 - 4 7.2 8.6 0.55 10.0 4.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 40 family DMPK_coil PF08826.10 KPI44215.1 - 0.075 13.2 0.5 0.23 11.6 0.5 1.8 1 0 0 1 1 1 0 DMPK coiled coil domain like 2-Hacid_dh PF00389.30 KPI44215.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Syntaxin-6_N PF09177.11 KPI44215.1 - 0.13 12.8 1.9 0.14 12.7 0.4 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 KPI44215.1 - 0.31 11.1 4.3 0.24 11.5 0.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein WEMBL PF05701.11 KPI44216.1 - 0.007 15.1 0.1 0.0086 14.8 0.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light PDZ_assoc PF10600.9 KPI44216.1 - 0.028 15.2 0.1 0.045 14.6 0.1 1.3 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors F-box PF00646.33 KPI44216.1 - 0.047 13.6 0.3 0.15 11.9 0.3 2.1 1 1 1 2 2 2 0 F-box domain BDV_P24 PF06595.11 KPI44216.1 - 0.086 12.7 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein TFIIE_alpha PF02002.17 KPI44216.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Lactamase_B_2 PF12706.7 KPI44217.1 - 6.5e-09 35.6 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KPI44217.1 - 0.0027 17.8 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KPI44217.1 - 0.073 13.1 0.2 0.3 11.1 0.2 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PAN_4 PF14295.6 KPI44218.1 - 1.4e-13 50.5 12.9 0.00031 20.6 0.7 4.0 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KPI44218.1 - 1.7e-06 27.9 22.7 0.01 15.8 0.3 4.2 4 0 0 4 4 4 3 PAN domain PAN_3 PF08277.12 KPI44218.1 - 0.0031 17.3 19.5 0.073 12.9 1.6 4.0 3 0 0 3 3 3 3 PAN-like domain zf-RING_2 PF13639.6 KPI44219.1 - 1.2e-12 47.9 4.7 2.3e-12 47.0 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KPI44219.1 - 4.6e-09 35.9 2.1 4.6e-09 35.9 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 KPI44219.1 - 1.4e-08 34.6 0.0 3.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KPI44219.1 - 4.9e-08 33.1 2.1 4.9e-08 33.1 2.1 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KPI44219.1 - 4.9e-08 32.7 2.2 8.3e-08 32.0 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI44219.1 - 5.1e-08 32.6 3.4 8.7e-08 31.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI44219.1 - 1.6e-07 31.1 1.7 2.7e-07 30.4 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KPI44219.1 - 1.7e-05 24.6 2.6 2.8e-05 23.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI44219.1 - 3.8e-05 23.6 1.7 0.00027 20.9 2.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KPI44219.1 - 0.0024 17.7 2.7 0.0043 16.9 2.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KPI44219.1 - 0.0052 16.8 0.6 0.011 15.7 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KPI44219.1 - 0.091 12.9 3.7 0.22 11.7 3.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KPI44219.1 - 0.2 11.5 3.1 0.38 10.6 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KPI44219.1 - 0.31 11.3 1.9 0.8 9.9 1.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KPI44219.1 - 0.43 10.5 2.7 0.81 9.6 2.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KPI44219.1 - 1.2 9.5 2.9 2.4 8.6 2.9 1.5 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KPI44219.1 - 1.3 9.2 3.1 2.8 8.2 3.1 1.6 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KPI44219.1 - 8.1 6.2 9.0 0.3 10.8 3.0 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type cNMP_binding PF00027.29 KPI44220.1 - 8.6e-31 105.9 0.6 8.4e-19 67.4 0.0 5.4 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KPI44220.1 - 1.7e-15 57.8 6.7 1.7e-15 57.8 6.7 3.8 2 2 0 3 3 3 1 Patatin-like phospholipase Mitochondr_Som1 PF11093.8 KPI44221.1 - 1.1e-20 73.4 0.2 1.6e-20 72.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Sporozoite_P67 PF05642.11 KPI44222.1 - 0.0013 17.0 3.2 0.0014 16.9 3.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen RAP1 PF07218.11 KPI44222.1 - 3.9 5.7 7.6 4.3 5.5 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cu_amine_oxid PF01179.20 KPI44223.1 - 1.1e-157 525.3 0.0 1.8e-157 524.5 0.0 1.3 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KPI44223.1 - 6.9e-07 29.4 0.0 4.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KPI44223.1 - 0.0015 18.9 0.4 0.0039 17.6 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Glyoxalase PF00903.25 KPI44224.1 - 1.4e-13 51.2 4.3 3.8e-11 43.3 1.7 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RGS PF00615.19 KPI44225.1 - 5.3e-09 36.4 0.0 8.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Abhydrolase_3 PF07859.13 KPI44226.1 - 2.1e-17 63.7 0.0 3.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPI44226.1 - 2e-14 53.3 0.0 5e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase zf-MYND PF01753.18 KPI44227.1 - 1.2e-07 31.7 14.9 1.9e-07 31.1 14.3 1.6 1 1 0 1 1 1 1 MYND finger MMM1 PF10296.9 KPI44228.1 - 1.5e-123 412.1 0.0 1.8e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PI3K_1B_p101 PF10486.9 KPI44229.1 - 0.088 10.6 3.1 0.13 10.0 3.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GST_N_3 PF13417.6 KPI44230.1 - 2.5e-15 56.7 0.0 4.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI44230.1 - 2.6e-13 49.8 0.0 6.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI44230.1 - 3.2e-13 49.8 0.2 9.4e-13 48.3 0.0 1.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI44230.1 - 5.9e-12 45.6 0.0 9.1e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI44230.1 - 2.4e-08 34.1 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI44230.1 - 8.1e-06 26.1 0.1 2.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KPI44230.1 - 0.00021 21.0 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF223 PF02721.14 KPI44230.1 - 0.001 19.3 0.0 0.0029 17.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF223 GST_N_4 PF17172.4 KPI44230.1 - 0.025 15.3 0.0 0.047 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Ribosomal_L27A PF00828.19 KPI44232.1 - 2.4e-15 57.3 2.8 5.3e-14 53.0 1.5 2.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Rick_17kDa_Anti PF05433.15 KPI44233.1 - 0.00049 19.9 14.2 0.0053 16.6 13.0 2.3 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KPI44233.1 - 0.0067 16.4 12.1 0.017 15.1 10.7 2.1 2 0 0 2 2 2 1 Glycine zipper PCMT PF01135.19 KPI44234.1 - 1.5e-61 207.9 0.0 1.7e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KPI44234.1 - 9.7e-09 35.8 0.1 1.9e-08 34.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI44234.1 - 1.2e-08 34.9 0.2 3e-08 33.6 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPI44234.1 - 5.3e-06 26.5 0.0 7.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI44234.1 - 2.5e-05 24.8 0.0 4.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI44234.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KPI44234.1 - 8.6e-05 22.4 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI44234.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KPI44234.1 - 0.00032 19.7 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KPI44234.1 - 0.0024 18.6 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KPI44234.1 - 0.033 15.2 0.0 0.063 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KPI44234.1 - 0.034 13.7 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KPI44234.1 - 0.05 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KPI44234.1 - 0.14 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3328 PF11807.8 KPI44235.1 - 2.8e-19 69.8 6.9 4e-19 69.3 6.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PTPRCAP PF15713.5 KPI44236.1 - 0.067 13.5 16.6 0.076 13.3 16.6 1.0 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CAF-1_p150 PF11600.8 KPI44236.1 - 0.13 12.0 28.0 0.22 11.2 28.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FKBP_N PF01346.18 KPI44236.1 - 0.17 12.8 8.6 0.2 12.6 8.6 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Bud13 PF09736.9 KPI44236.1 - 0.38 11.2 16.8 0.48 10.8 16.8 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PMSI1 PF15322.6 KPI44236.1 - 1.1 8.6 5.4 1.2 8.5 5.4 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Usp PF00582.26 KPI44236.1 - 2.4 8.7 9.5 3.2 8.3 9.5 1.2 1 0 0 1 1 1 0 Universal stress protein family Presenilin PF01080.17 KPI44236.1 - 3.8 6.2 8.1 4.2 6.0 8.1 1.0 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 KPI44236.1 - 4.7 7.5 15.9 5.3 7.3 15.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 KPI44236.1 - 4.7 6.9 15.0 5.5 6.7 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KPI44236.1 - 6.7 6.7 22.7 8 6.5 22.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.16 KPI44236.1 - 7.7 5.6 11.3 8.7 5.4 11.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GATase_5 PF13507.6 KPI44237.1 - 4.7e-73 245.5 0.0 8.7e-73 244.6 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KPI44237.1 - 1.7e-39 135.5 0.1 1.2e-26 93.7 0.2 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KPI44237.1 - 2.8e-34 117.6 0.0 4.8e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KPI44237.1 - 6.3e-21 74.7 0.0 1.3e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain MFS_1 PF07690.16 KPI44238.1 - 5.1e-34 117.8 34.9 5.1e-34 117.8 34.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UL41A PF17591.2 KPI44238.1 - 0.002 18.2 1.0 0.002 18.2 1.0 2.1 2 0 0 2 2 2 1 Herpesvirus UL41A OATP PF03137.20 KPI44238.1 - 8.6 4.5 10.1 29 2.8 5.8 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tam41_Mmp37 PF09139.11 KPI44239.1 - 1.2e-130 435.7 0.0 1.5e-130 435.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial GEMIN8 PF15348.6 KPI44239.1 - 0.19 12.0 4.7 0.4 11.0 1.8 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Frag1 PF10277.9 KPI44240.1 - 2.9e-39 134.9 8.7 2.9e-39 134.9 8.7 2.5 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Epimerase PF01370.21 KPI44241.1 - 2.1e-12 47.0 0.0 4.6e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI44241.1 - 4.8e-09 36.1 0.0 1.7e-08 34.2 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI44241.1 - 3.4e-08 32.8 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KPI44241.1 - 5.1e-07 29.8 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPI44241.1 - 1.9e-05 24.0 0.0 0.004 16.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KPI44241.1 - 2.1e-05 24.2 0.0 4.3e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KPI44241.1 - 0.00032 20.2 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KPI44241.1 - 0.042 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Poxvirus_B22R_N PF13169.6 KPI44241.1 - 0.16 12.5 0.1 2 9.0 0.0 2.6 2 1 1 3 3 3 0 Poxvirus B22R protein N-terminal RmlD_sub_bind PF04321.17 KPI44241.1 - 0.17 11.0 0.1 0.42 9.7 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Methyltransf_23 PF13489.6 KPI44242.1 - 5.6e-13 49.0 0.0 8.6e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI44242.1 - 2.8e-05 24.8 0.1 0.4 11.4 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KPI44242.1 - 6.6e-05 22.7 0.0 0.35 10.7 0.1 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KPI44242.1 - 0.0012 19.4 0.1 0.069 13.8 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI44242.1 - 0.0013 19.5 0.0 0.39 11.5 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain TehB PF03848.14 KPI44242.1 - 0.0046 16.4 0.0 0.1 12.0 0.0 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.14 KPI44242.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Copine PF07002.16 KPI44242.1 - 0.23 10.9 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 Copine TP_methylase PF00590.20 KPI44243.1 - 4.2e-35 121.6 0.7 4.2e-35 121.6 0.7 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 KPI44243.1 - 1.1e-10 40.9 0.1 1.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KPI44243.1 - 1.3e-09 37.3 0.5 2.9e-09 36.2 0.5 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 KPI44243.1 - 6.9e-07 29.7 0.0 1.6e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding SpoU_sub_bind PF08032.12 KPI44244.1 - 2.7e-10 40.4 0.0 1.6e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding SpoU_methylase PF00588.19 KPI44244.1 - 0.00088 19.5 0.0 0.0024 18.1 0.0 1.7 2 0 0 2 2 2 1 SpoU rRNA Methylase family Exo70 PF03081.15 KPI44245.1 - 0.039 13.0 3.2 1.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Exo70 exocyst complex subunit DNA_repr_REX1B PF14966.6 KPI44245.1 - 0.1 13.3 0.2 1.3 9.8 0.1 2.2 2 0 0 2 2 2 0 DNA repair REX1-B MAM1 PF10434.9 KPI44245.1 - 0.18 11.4 1.9 0.76 9.3 0.1 2.1 2 0 0 2 2 2 0 Monopolin complex protein MAM1 FAA_hydrolase PF01557.18 KPI44246.1 - 1.9e-47 161.8 0.0 2.6e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPI44246.1 - 4.7e-24 84.6 0.0 7.9e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal TMEM154 PF15102.6 KPI44247.1 - 0.1 12.5 1.4 0.13 12.1 1.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family DASH_Dam1 PF08653.10 KPI44248.1 - 6.5e-27 93.1 1.2 8.8e-27 92.7 1.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 GIDA PF01134.22 KPI44249.1 - 3.7e-152 507.0 0.0 4.8e-152 506.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KPI44249.1 - 5.7e-64 216.2 0.0 9.1e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KPI44249.1 - 9e-07 28.6 0.7 1.5e-06 27.8 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI44249.1 - 4e-06 26.3 0.4 9e-06 25.1 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI44249.1 - 0.0018 17.4 5.5 0.0038 16.4 4.5 2.0 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KPI44249.1 - 0.0063 15.3 0.9 0.058 12.1 0.4 2.3 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KPI44249.1 - 0.0086 15.4 0.4 0.018 14.4 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KPI44249.1 - 0.12 11.4 0.3 0.37 9.8 0.3 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KPI44249.1 - 0.16 10.8 0.8 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 KPI44249.1 - 0.21 11.1 2.2 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPI44249.1 - 0.82 8.9 4.4 0.47 9.7 0.2 2.1 2 0 0 2 2 2 0 Thi4 family Med9 PF07544.13 KPI44250.1 - 1.1e-11 44.6 0.5 2.2e-09 37.3 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 EBP PF05241.12 KPI44251.1 - 0.051 13.0 7.7 0.04 13.4 4.7 1.9 2 0 0 2 2 2 0 Emopamil binding protein Acetyltransf_1 PF00583.25 KPI44253.1 - 1.8e-11 44.3 0.1 4.6e-11 43.0 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI44253.1 - 1.7e-10 41.1 0.0 3.3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI44253.1 - 1.1e-09 38.3 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI44253.1 - 2.4e-05 24.4 0.0 0.0014 18.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KPI44253.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GST_N_3 PF13417.6 KPI44254.1 - 9.6e-20 70.8 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI44254.1 - 8e-18 64.5 0.5 1.9e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI44254.1 - 3e-11 43.5 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KPI44254.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI44254.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI44254.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Barwin PF00967.17 KPI44255.1 - 0.067 13.1 0.1 2.5 8.0 0.0 2.4 1 1 0 2 2 2 0 Barwin family HET PF06985.11 KPI44256.1 - 9.1e-06 26.1 0.0 0.022 15.1 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RabGAP-TBC PF00566.18 KPI44257.1 - 2.4e-36 125.4 0.1 4.3e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Zn_clus PF00172.18 KPI44258.1 - 1.5e-05 25.0 8.1 2.7e-05 24.2 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI44258.1 - 0.00013 20.9 0.0 0.00019 20.4 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2615 PF11027.8 KPI44258.1 - 0.16 12.2 0.6 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) RTA1 PF04479.13 KPI44259.1 - 3.2e-56 190.2 8.3 3.2e-56 190.2 8.3 2.0 1 1 1 2 2 2 1 RTA1 like protein MscS_TM PF12794.7 KPI44259.1 - 0.0066 15.4 0.3 0.0066 15.4 0.3 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 Pox_A14 PF05767.12 KPI44259.1 - 0.03 14.5 1.7 0.054 13.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3382 PF11862.8 KPI44259.1 - 0.31 11.3 3.7 0.16 12.3 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Orf78 PF06024.12 KPI44259.1 - 4.5 7.6 5.7 58 4.1 0.0 2.7 3 0 0 3 3 3 0 Orf78 (ac78) WD40 PF00400.32 KPI44260.1 - 1.4e-21 76.4 19.3 0.00023 21.9 0.9 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KPI44260.1 - 0.002 16.7 0.3 0.15 10.6 0.0 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 KPI44260.1 - 0.0042 17.0 0.6 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KPI44260.1 - 0.0043 17.5 0.5 14 6.3 0.1 3.8 3 0 0 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 KPI44260.1 - 0.015 15.6 0.0 0.33 11.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GET2 PF08690.10 KPI44260.1 - 0.99 9.0 2.1 1.5 8.4 2.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Nop14 PF04147.12 KPI44260.1 - 6.8 4.8 9.7 12 3.9 9.7 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-F_leu_zip PF10473.9 KPI44261.1 - 0.0014 18.6 16.3 0.083 12.9 9.8 2.7 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KPI44261.1 - 0.0024 18.1 16.6 0.0024 18.1 16.6 3.5 2 2 0 2 2 2 1 Autophagy protein 16 (ATG16) Trimer_CC PF08954.11 KPI44261.1 - 0.04 13.5 0.8 0.37 10.4 0.8 2.7 1 0 0 1 1 1 0 Trimerisation motif DUF4201 PF13870.6 KPI44261.1 - 0.27 10.9 18.7 2.9 7.6 11.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.6 KPI44261.1 - 0.37 10.1 23.2 0.78 9.1 14.4 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 KPI44261.1 - 0.52 10.4 24.7 0.58 10.2 14.1 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Taxilin PF09728.9 KPI44261.1 - 0.66 9.1 17.2 1.3 8.1 11.3 2.4 2 0 0 2 2 2 0 Myosin-like coiled-coil protein ADIP PF11559.8 KPI44261.1 - 1.4 9.0 18.6 0.49 10.5 6.4 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.9 KPI44261.1 - 1.5 9.1 11.8 0.064 13.6 4.3 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 KPI44261.1 - 2.5 8.8 22.3 0.64 10.7 0.4 5.6 3 1 2 5 5 5 0 SlyX PspA_IM30 PF04012.12 KPI44261.1 - 3.5 7.1 26.2 2.1 7.9 11.8 3.1 1 1 0 2 2 2 0 PspA/IM30 family SabA_adhesion PF18304.1 KPI44262.1 - 0.0052 16.1 5.3 0.041 13.1 5.1 2.2 1 1 0 1 1 1 1 SabA N-terminal extracellular adhesion domain UPF0149 PF03695.13 KPI44262.1 - 0.043 14.1 0.1 0.043 14.1 0.1 2.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0149) WAC_Acf1_DNA_bd PF10537.9 KPI44262.1 - 0.56 10.8 5.1 0.23 12.0 2.0 2.0 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Peptidase_C98 PF15499.6 KPI44262.1 - 4.2 6.8 10.4 1 8.8 0.2 3.1 2 1 1 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3287 PF11690.8 KPI44262.1 - 5.9 6.6 11.4 3.2 7.5 3.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) His_Phos_2 PF00328.22 KPI44263.1 - 1.3e-25 90.6 0.0 1.8e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PLA2_B PF01735.18 KPI44265.1 - 1.3e-16 60.1 0.0 3.2e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Peptidase_S9 PF00326.21 KPI44265.1 - 0.0051 16.3 0.1 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Arteri_GP4 PF02497.15 KPI44265.1 - 0.021 15.0 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus glycoprotein RasGAP PF00616.19 KPI44266.1 - 4.9e-55 186.5 0.3 1.4e-54 185.0 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KPI44266.1 - 2.4e-33 115.2 1.1 2.4e-33 115.2 1.1 2.9 3 0 0 3 3 3 1 RasGAP C-terminus CD36 PF01130.21 KPI44266.1 - 0.035 12.6 0.1 0.063 11.8 0.1 1.3 1 0 0 1 1 1 0 CD36 family DUF724 PF05266.14 KPI44266.1 - 6.5 6.5 8.0 2.8 7.7 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF724) CSN8_PSD8_EIF3K PF10075.9 KPI44267.1 - 2.1e-20 73.2 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KPI44267.1 - 2.7e-06 27.0 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family Fungal_trans PF04082.18 KPI44268.1 - 2.8e-14 52.8 0.0 4.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI44268.1 - 4.4e-08 33.1 10.3 4.4e-08 33.1 10.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KPI44269.1 - 5.6e-43 146.7 0.1 8.3e-43 146.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI44269.1 - 7.3e-28 97.1 0.4 2.7e-27 95.3 0.4 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI44269.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KPI44269.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Granulin PF00396.18 KPI44270.1 - 3.2 8.2 18.8 1.1e+03 0.0 18.8 2.6 1 1 0 1 1 1 0 Granulin Ribosomal_L30 PF00327.20 KPI44271.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e Beta-lactamase PF00144.24 KPI44272.1 - 3.7e-56 190.8 0.0 4.6e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase RMI1_N PF08585.12 KPI44273.1 - 7.6e-56 189.3 0.0 9.6e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Glyoxalase PF00903.25 KPI44274.1 - 0.0053 17.0 0.0 0.0067 16.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3060 PF11259.8 KPI44274.1 - 0.039 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) WD40 PF00400.32 KPI44275.1 - 4e-07 30.6 0.4 0.0025 18.6 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KPI44275.1 - 0.0012 17.6 0.1 0.34 9.6 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KPI44275.1 - 0.0017 18.6 0.0 1.2 9.4 0.0 3.4 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 KPI44276.1 - 1.2e-21 76.9 0.0 2.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI44276.1 - 2.6e-11 43.5 12.6 4.6e-11 42.7 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KIAA1430 PF13879.6 KPI44276.1 - 0.025 15.3 0.6 0.079 13.7 0.6 1.8 1 0 0 1 1 1 0 KIAA1430 homologue Sugarporin_N PF11471.8 KPI44276.1 - 0.18 11.8 0.8 0.53 10.3 0.8 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Gal4_dimer PF03902.13 KPI44276.1 - 0.31 11.3 0.9 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Gal4-like dimerisation domain NPR3 PF03666.13 KPI44278.1 - 8.8e-115 384.1 0.4 8.6e-101 338.0 0.1 3.2 3 1 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF4674 PF15719.5 KPI44278.1 - 4.6 7.2 8.2 12 5.9 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) Abhydrolase_4 PF08386.10 KPI44279.1 - 6.2e-19 68.0 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KPI44279.1 - 8.2e-14 51.9 0.0 1.5e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1295 PF06966.12 KPI44280.1 - 2.6e-09 36.9 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Put_Phosphatase PF06888.12 KPI44282.1 - 2.5e-37 128.5 0.2 1.7e-19 70.2 0.0 4.0 4 0 0 4 4 4 4 Putative Phosphatase HAD PF12710.7 KPI44282.1 - 0.00021 21.8 0.5 0.0087 16.5 0.0 3.2 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase BCS1_N PF08740.11 KPI44284.1 - 1.4e-40 139.3 0.1 1.9e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KPI44284.1 - 6.4e-17 62.2 0.0 1.1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KPI44284.1 - 0.00025 21.1 0.0 0.00062 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI44284.1 - 0.0008 19.8 0.0 0.0028 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KPI44284.1 - 0.0018 17.5 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KPI44284.1 - 0.0057 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 KPI44284.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPI44284.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KPI44284.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPI44284.1 - 0.025 15.1 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 KPI44284.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.6 KPI44284.1 - 0.034 13.9 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KPI44284.1 - 0.041 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KPI44284.1 - 0.057 13.7 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KPI44284.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KPI44284.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KPI44284.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KPI44284.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KPI44284.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KPI44285.1 - 7.7e-52 176.6 0.0 9.6e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2048 PF09752.9 KPI44285.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 zf-PARP PF00645.18 KPI44287.1 - 5.6e-22 78.4 1.2 5.6e-22 78.4 1.2 3.2 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Coilin_N PF15862.5 KPI44287.1 - 0.0012 18.7 1.6 0.0012 18.7 1.6 3.7 1 1 3 4 4 4 1 Coilin N-terminus DTHCT PF08070.11 KPI44287.1 - 3.4 8.5 73.6 9 7.1 28.2 3.6 1 1 2 3 3 3 0 DTHCT (NUC029) region GFO_IDH_MocA_C PF02894.17 KPI44288.1 - 3.7e-05 23.7 0.1 9.2e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ribonuclease_T2 PF00445.18 KPI44290.1 - 7.5e-08 32.8 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Glyco_hydro_47 PF01532.20 KPI44291.1 - 1.5e-144 482.3 0.0 1.8e-144 482.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad51 PF08423.11 KPI44292.1 - 5.9e-06 25.7 0.0 1.5e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Rad51 adh_short_C2 PF13561.6 KPI44292.1 - 2e-05 24.3 0.4 3.4e-05 23.5 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44292.1 - 0.00035 20.1 0.1 0.00065 19.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 KPI44293.1 - 2.1e-30 105.9 29.3 3e-30 105.4 29.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KPI44294.1 - 2.6e-55 187.6 0.0 3.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44294.1 - 1.7e-20 73.4 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KPI44294.1 - 5.5e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI44294.1 - 0.0006 19.8 0.2 0.17 11.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI44294.1 - 0.00065 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPI44294.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KPI44294.1 - 0.015 14.9 0.2 0.05 13.2 0.1 1.7 1 1 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KPI44294.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAS_8 PF13188.7 KPI44294.1 - 0.11 12.5 0.0 3.5 7.7 0.0 3.1 4 0 0 4 4 4 0 PAS domain AlaDh_PNT_N PF05222.15 KPI44295.1 - 7.2e-28 97.6 0.0 1.1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KPI44295.1 - 0.00034 20.0 0.0 0.00085 18.7 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ARD PF03079.14 KPI44297.1 - 2.5e-43 148.0 0.1 3e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KPI44297.1 - 4.7e-09 35.8 0.0 1.2e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KPI44297.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short_C2 PF13561.6 KPI44298.1 - 1.1e-36 126.5 0.1 1.4e-36 126.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44298.1 - 3.8e-33 114.6 0.0 4.8e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI44298.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Prenyltransf PF01255.19 KPI44298.1 - 0.066 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Abhydrolase_1 PF00561.20 KPI44299.1 - 5.1e-15 55.8 0.0 6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44299.1 - 7.2e-14 52.9 0.0 8.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI44299.1 - 2.7e-07 30.1 0.0 3.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPI44299.1 - 0.0012 19.0 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 KPI44299.1 - 0.004 16.2 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 KPI44299.1 - 0.0051 16.7 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KPI44299.1 - 0.01 15.6 1.3 0.032 13.9 1.3 1.8 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KPI44299.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Esterase PF00756.20 KPI44299.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 KPI44299.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 KPI44299.1 - 0.022 14.3 0.5 0.053 13.1 0.3 1.7 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 KPI44299.1 - 0.033 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase PF07224.11 KPI44299.1 - 0.039 13.0 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase DUF915 PF06028.11 KPI44299.1 - 0.088 12.1 0.0 0.7 9.2 0.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lactamase_B PF00753.27 KPI44301.1 - 4.3e-11 43.2 0.1 7.8e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Yae1_N PF09811.9 KPI44301.1 - 2.3e-09 36.8 0.0 3.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Lactamase_B_2 PF12706.7 KPI44301.1 - 1.3e-05 24.8 0.1 3.4e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI44301.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Dor1 PF04124.12 KPI44302.1 - 4e-45 154.0 6.6 2.5e-32 111.9 6.3 2.1 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KPI44302.1 - 0.13 12.4 1.6 0.48 10.5 1.6 2.0 1 0 0 1 1 1 0 Vps51/Vps67 Methyltransf_2 PF00891.18 KPI44303.1 - 4.7e-14 52.2 0.4 2.3e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 KPI44303.1 - 0.025 14.6 0.3 0.12 12.4 0.0 2.4 3 0 0 3 3 3 0 Dimerisation domain Hydin_ADK PF17213.3 KPI44303.1 - 0.065 13.5 0.1 0.093 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MFS_1 PF07690.16 KPI44304.1 - 4.1e-36 124.6 35.1 4.1e-36 124.6 35.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44304.1 - 7.4e-05 21.8 1.4 7.4e-05 21.8 1.4 3.1 4 0 0 4 4 4 1 Sugar (and other) transporter Nuc_deoxyrib_tr PF05014.15 KPI44305.1 - 1.3e-09 38.1 0.0 1.7e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase CDP-OH_P_transf PF01066.21 KPI44306.1 - 1.9e-13 51.0 2.4 2e-13 50.9 0.4 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pep_deformylase PF01327.21 KPI44307.1 - 2.2e-26 92.3 0.0 2.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Transthyretin PF00576.21 KPI44308.1 - 5.9e-31 107.4 0.0 8.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Acyl-CoA_dh_N PF02771.16 KPI44309.1 - 1.6e-20 73.9 0.0 4.3e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI44309.1 - 1.3e-17 63.7 0.0 2.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KPI44309.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain UCH PF00443.29 KPI44310.1 - 4.6e-47 160.7 0.1 5.7e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KPI44310.1 - 1.6e-17 64.1 3.2 9.6e-17 61.5 3.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KPI44310.1 - 0.00012 22.3 0.8 0.0044 17.3 0.4 3.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF116 PF01976.17 KPI44310.1 - 0.09 12.3 4.5 0.032 13.7 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF116 zinc_ribbon_13 PF09855.9 KPI44310.1 - 0.12 12.6 6.4 12 6.1 0.1 3.8 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ZZ PF00569.17 KPI44310.1 - 0.87 9.4 5.3 1.9 8.4 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, ZZ type BTB PF00651.31 KPI44312.1 - 2.8e-14 53.3 0.0 2.1e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain FAD_binding_7 PF03441.14 KPI44313.1 - 5.9e-58 195.7 1.2 1.1e-56 191.6 1.2 2.1 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KPI44313.1 - 5.2e-31 107.9 0.0 9.5e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase PBP1_TM PF14812.6 KPI44313.1 - 2.7 8.4 9.3 8.1 6.9 9.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sugar_tr PF00083.24 KPI44314.1 - 2.4e-101 339.9 15.1 2.9e-101 339.6 15.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44314.1 - 3.1e-31 108.6 47.6 1.3e-27 96.6 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.23 KPI44315.1 - 3.3e-64 217.3 1.4 5.2e-64 216.6 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI44315.1 - 1.5e-09 38.4 8.7 1.2e-08 35.4 2.8 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KPI44315.1 - 5.1e-05 23.8 6.8 0.19 12.4 0.4 4.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KPI44315.1 - 0.0018 18.8 2.9 3.5 8.3 0.0 3.9 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KPI44315.1 - 0.0045 16.8 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4407 PF14362.6 KPI44316.1 - 0.025 14.0 2.0 0.039 13.3 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 KPI44316.1 - 0.096 13.6 0.1 0.27 12.2 0.1 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain MFS_1 PF07690.16 KPI44317.1 - 2.7e-40 138.4 30.1 2.7e-40 138.4 30.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Adaptin_N PF01602.20 KPI44318.1 - 2.1e-143 478.7 4.1 2.5e-143 478.4 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KPI44318.1 - 6.5e-21 74.7 0.0 2.4e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 KPI44318.1 - 8.1e-09 35.7 7.7 1.3e-05 25.3 0.1 4.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPI44318.1 - 5.1e-06 26.8 0.5 0.14 12.5 0.0 4.1 3 1 1 4 4 4 3 HEAT repeats DUF3730 PF12530.8 KPI44318.1 - 0.0011 18.5 0.5 0.011 15.3 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) HEAT PF02985.22 KPI44318.1 - 0.0041 17.3 2.1 6.5 7.3 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat GET2 PF08690.10 KPI44318.1 - 0.0071 16.1 1.5 0.014 15.1 1.5 1.6 1 0 0 1 1 1 1 GET complex subunit GET2 CLASP_N PF12348.8 KPI44318.1 - 0.053 13.1 0.2 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal RICTOR_M PF14666.6 KPI44318.1 - 0.069 12.9 0.0 0.28 11.0 0.0 2.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain CWC25 PF12542.8 KPI44319.1 - 3e-26 92.3 2.2 3e-26 92.3 2.2 3.6 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KPI44319.1 - 1.9e-15 56.7 12.4 1.9e-15 56.7 12.4 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR 2OG-FeII_Oxy_3 PF13640.6 KPI44320.1 - 6.5e-08 33.4 0.0 2.2e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily U3_assoc_6 PF08640.11 KPI44321.1 - 2e-27 95.1 9.1 8.5e-27 93.1 2.4 2.8 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KPI44321.1 - 4.3e-06 27.1 4.3 0.054 14.3 0.2 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat NRDE-2 PF08424.10 KPI44321.1 - 1.1e-05 24.8 2.0 0.0004 19.6 0.1 2.8 1 1 1 3 3 3 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KPI44321.1 - 0.0021 18.5 2.7 0.071 13.6 0.0 4.0 3 3 1 4 4 4 1 Tetratricopeptide repeat SAM_1 PF00536.30 KPI44321.1 - 0.1 13.1 0.0 16 6.0 0.0 3.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) DUF5315 PF17242.2 KPI44321.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.7 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) PCI PF01399.27 KPI44322.1 - 3.1e-11 43.7 0.0 1.1e-10 41.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KPI44322.1 - 0.00082 19.3 1.0 0.0028 17.6 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KPI44322.1 - 0.036 13.9 1.0 0.11 12.4 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI44322.1 - 0.06 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Xpo1 PF08389.12 KPI44323.1 - 8.6e-05 22.6 6.9 0.0024 18.0 0.1 4.2 4 0 0 4 4 4 1 Exportin 1-like protein MMS19_N PF14500.6 KPI44323.1 - 0.013 15.1 2.2 0.34 10.4 0.1 3.6 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II IBN_N PF03810.19 KPI44323.1 - 0.025 14.5 0.0 0.082 12.8 0.0 2.0 1 0 0 1 1 1 0 Importin-beta N-terminal domain SpoU_methylase PF00588.19 KPI44324.1 - 7.9e-10 39.1 0.0 8.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family PhyH PF05721.13 KPI44325.1 - 1.9e-36 126.3 0.0 2.4e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KPI44325.1 - 0.0093 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.11 KPI44326.1 - 9.5e-06 25.2 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Form_Nir_trans PF01226.17 KPI44328.1 - 1.1e-48 165.6 13.0 1.4e-48 165.3 13.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Herpes_UL79 PF03049.14 KPI44328.1 - 0.0054 16.4 0.2 0.0077 15.9 0.2 1.2 1 0 0 1 1 1 1 UL79 family Glyco_hydro_3_C PF01915.22 KPI44329.1 - 3.5e-46 157.7 0.0 5.4e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KPI44329.1 - 8.9e-38 130.4 0.0 1.5e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KPI44329.1 - 1.6e-14 53.7 0.4 3.2e-14 52.8 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PIR PF00399.19 KPI44329.1 - 1.2e-05 24.7 3.2 2.6e-05 23.6 3.2 1.6 1 0 0 1 1 1 1 Yeast PIR protein repeat NAD_binding_10 PF13460.6 KPI44331.1 - 9.5e-25 87.5 0.7 1.3e-24 87.1 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI44331.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI44331.1 - 0.059 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KPI44332.1 - 2.9e-12 46.7 0.0 7.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI44332.1 - 1.8e-11 43.9 0.0 5.9e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI44332.1 - 0.00037 21.6 0.1 0.00084 20.4 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI44332.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase FliE PF02049.18 KPI44332.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE PGM_PMM_I PF02878.16 KPI44333.1 - 5e-18 65.1 0.2 2.9e-09 36.7 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KPI44333.1 - 1.5e-11 44.3 1.0 4.7e-11 42.7 1.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KPI44333.1 - 0.002 18.7 0.4 0.031 14.9 0.1 3.0 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KPI44333.1 - 0.067 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1279 PF06916.13 KPI44334.1 - 4.3e-27 94.5 0.0 8.2e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SAS4 PF15460.6 KPI44335.1 - 0.021 14.9 0.3 0.097 12.8 0.3 2.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Spectrin PF00435.21 KPI44335.1 - 0.2 12.2 11.8 0.71 10.4 1.1 4.1 3 1 1 4 4 4 0 Spectrin repeat Ribosomal_L29 PF00831.23 KPI44335.1 - 0.31 11.0 2.3 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein Img2 PF05046.14 KPI44335.1 - 0.38 11.1 3.7 23 5.4 0.1 3.5 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Lebercilin PF15619.6 KPI44335.1 - 4.2 7.0 7.5 10 5.7 2.6 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 KPI44335.1 - 7.9 7.2 6.6 3.3 8.4 0.1 3.3 4 1 0 4 4 4 0 Initiation control protein YabA tRNA-synt_2 PF00152.20 KPI44336.1 - 2.3e-58 197.7 0.0 4.2e-58 196.9 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KPI44336.1 - 4.2e-06 26.4 0.2 0.0059 16.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KPI44336.1 - 0.0006 19.7 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WD40 PF00400.32 KPI44337.1 - 6.2e-16 58.5 12.1 5.8e-05 23.8 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI44337.1 - 5.7e-11 42.6 0.1 0.47 10.8 0.1 5.7 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KPI44337.1 - 0.00049 18.7 0.0 0.00099 17.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 KPI44337.1 - 0.00065 19.6 0.0 0.008 16.1 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KPI44337.1 - 1.3 9.1 6.2 1.5 8.8 0.5 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CUE PF02845.16 KPI44338.1 - 6.3e-05 22.6 0.1 0.00018 21.2 0.1 1.8 1 0 0 1 1 1 1 CUE domain GldM_N PF12081.8 KPI44338.1 - 0.028 14.5 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 GldM N-terminal domain QSregVF PF13652.6 KPI44338.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Glyco_hydro_5_C PF18564.1 KPI44339.1 - 1.4e-22 80.0 0.0 3.3e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KPI44339.1 - 3.3e-13 49.7 3.5 1.5e-08 34.4 1.2 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KPI44339.1 - 0.00072 19.0 4.5 0.043 13.1 0.1 2.4 3 0 0 3 3 3 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 KPI44339.1 - 0.012 15.3 0.2 0.025 14.2 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 Chalcone_2 PF16035.5 KPI44340.1 - 1.2e-77 260.3 0.0 1.2e-77 260.3 0.0 1.6 2 0 0 2 2 2 1 Chalcone isomerase like Chalcone_3 PF16036.5 KPI44340.1 - 0.00095 19.3 0.0 0.0067 16.6 0.0 2.3 2 0 0 2 2 2 1 Chalcone isomerase-like DUF3433 PF11915.8 KPI44341.1 - 5.9e-11 42.7 2.2 5.9e-11 42.7 2.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) Abhydrolase_1 PF00561.20 KPI44343.1 - 1.5e-15 57.5 0.0 9.3e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44343.1 - 9.8e-05 23.1 0.1 0.00019 22.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KPI44343.1 - 0.0052 16.5 0.1 0.0072 16.0 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KPI44343.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFMR_assoc PF16596.5 KPI44344.1 - 1.5 9.3 12.2 4.3 7.8 12.2 1.9 1 0 0 1 1 1 0 Disordered region downstream of MFMR TIMELESS PF04821.14 KPI44345.1 - 4.4e-83 278.7 0.0 1.5e-82 277.0 0.0 2.0 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KPI44345.1 - 1.5e-30 106.9 30.7 1.5e-30 106.9 30.7 3.8 3 1 0 3 3 3 2 Timeless protein C terminal region Fungal_trans_2 PF11951.8 KPI44346.1 - 3.3e-09 36.0 0.0 5.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_5 PF13857.6 KPI44347.1 - 1.5e-08 34.7 0.2 0.16 12.3 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI44347.1 - 2.6e-07 30.4 0.1 0.019 15.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KPI44347.1 - 3.5e-06 27.5 0.0 9e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KPI44347.1 - 0.00064 20.1 0.0 1.7 9.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KPI44347.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Clathrin PF00637.20 KPI44347.1 - 0.035 14.0 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Region in Clathrin and VPS GAT PF03127.14 KPI44347.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 GAT domain GTP_EFTU PF00009.27 KPI44348.1 - 1.2e-54 184.9 0.0 1.7e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KPI44348.1 - 1.8e-41 141.0 0.0 3.8e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KPI44348.1 - 4e-13 49.6 1.8 4e-13 49.6 1.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIS_C PF01096.18 KPI44348.1 - 1.3e-11 44.2 0.2 2.5e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) MMR_HSR1 PF01926.23 KPI44348.1 - 0.0011 19.0 0.1 0.022 14.9 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PDZ PF00595.24 KPI44348.1 - 0.076 13.4 0.2 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Semialdhyde_dhC PF02774.18 KPI44348.1 - 0.08 13.0 0.1 0.3 11.1 0.0 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Spc7 PF08317.11 KPI44348.1 - 0.12 11.2 0.4 0.2 10.5 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein G-alpha PF00503.20 KPI44348.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KPI44348.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family WD40 PF00400.32 KPI44349.1 - 4.9e-23 81.0 1.1 8.9e-10 39.0 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI44349.1 - 1.6e-11 44.3 0.0 4.7e-05 23.6 0.0 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KPI44349.1 - 0.00048 18.8 0.1 0.0015 17.1 0.1 1.8 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 KPI44349.1 - 0.0011 17.8 0.1 0.003 16.3 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KPI44349.1 - 0.0011 18.6 0.1 0.017 14.7 0.0 2.4 1 1 2 3 3 3 1 PQQ-like domain eIF2A PF08662.11 KPI44349.1 - 0.0012 18.8 0.3 2.2 8.1 0.0 3.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KPI44349.1 - 0.0065 15.8 0.0 0.12 11.7 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KPI44349.1 - 0.097 11.6 0.2 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WSC PF01822.19 KPI44350.1 - 1.4e-05 25.2 3.8 1.4e-05 25.2 3.8 3.8 4 0 0 4 4 4 1 WSC domain PAN_4 PF14295.6 KPI44350.1 - 0.039 13.9 4.5 0.96 9.4 0.1 3.9 3 0 0 3 3 3 0 PAN domain PAN_1 PF00024.26 KPI44350.1 - 0.12 12.4 23.0 0.2 11.7 0.9 4.5 4 1 0 4 4 4 0 PAN domain SWIB PF02201.18 KPI44351.1 - 5.8e-22 77.4 0.0 2.1e-21 75.6 0.0 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain SPX PF03105.19 KPI44352.1 - 3.5e-50 172.0 10.5 4.4e-50 171.7 10.5 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 KPI44352.1 - 1.5e-07 31.4 12.6 8.9e-07 29.0 11.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KPI44352.1 - 2.9e-07 30.2 8.8 5.2e-07 29.4 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI44352.1 - 3.5e-06 26.8 11.2 7.6e-06 25.7 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI44352.1 - 1.6e-05 24.8 9.8 3.4e-05 23.7 9.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPI44352.1 - 2.6e-05 24.0 11.9 2.6e-05 24.0 11.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI44352.1 - 6.3e-05 23.2 11.8 0.00013 22.2 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI44352.1 - 8.3e-05 22.5 8.7 0.00022 21.2 8.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DUF3540 PF12059.8 KPI44352.1 - 0.0075 16.1 0.6 0.021 14.7 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3540) Prok-RING_4 PF14447.6 KPI44352.1 - 0.0079 16.0 9.2 0.021 14.6 9.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KPI44352.1 - 0.0098 15.9 2.6 0.019 15.0 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KPI44352.1 - 0.021 14.6 3.9 0.021 14.6 3.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF572 PF04502.13 KPI44352.1 - 0.24 11.0 0.0 0.24 11.0 0.0 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF572) TerY_C PF15616.6 KPI44352.1 - 0.24 11.5 2.5 0.53 10.4 2.5 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain NOB1_Zn_bind PF08772.11 KPI44352.1 - 0.25 11.5 4.6 3.2 8.0 4.5 2.5 2 1 0 2 2 1 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_6 PF14835.6 KPI44352.1 - 0.28 11.1 3.9 0.68 9.8 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KPI44352.1 - 0.58 10.5 9.3 1.6 9.1 9.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KPI44352.1 - 1 9.0 8.7 12 5.6 8.8 2.2 1 1 1 2 2 2 0 P-11 zinc finger zf-Sec23_Sec24 PF04810.15 KPI44352.1 - 1.9 8.6 6.6 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger MbeD_MobD PF04899.12 KPI44352.1 - 1.9 8.6 6.6 4.6 7.4 0.5 3.0 2 1 1 3 3 3 0 MbeD/MobD like FMN_dh PF01070.18 KPI44353.1 - 7.6e-111 370.5 0.0 9.5e-111 370.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KPI44353.1 - 4.7e-19 68.3 0.1 9.4e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KPI44353.1 - 1.8e-05 24.1 0.1 2.7e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KPI44353.1 - 5.5e-05 22.3 0.1 0.00013 21.1 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KPI44353.1 - 0.0067 15.8 0.1 1.7 7.9 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KPI44353.1 - 0.012 15.1 0.2 0.042 13.2 0.1 1.8 1 1 1 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.21 KPI44353.1 - 0.062 12.8 0.0 0.57 9.6 0.0 2.1 1 1 0 2 2 2 0 Histidine biosynthesis protein Lactamase_B_2 PF12706.7 KPI44355.1 - 3.5e-20 72.4 0.0 8.3e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI44355.1 - 3.3e-11 43.3 0.0 6.8e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPI44355.1 - 0.00012 22.1 1.5 0.0049 16.9 1.0 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily zf-C2H2 PF00096.26 KPI44356.1 - 4.8e-07 29.9 17.0 3.1e-05 24.2 2.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KPI44356.1 - 4.3e-05 23.7 3.8 4.3e-05 23.7 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KPI44356.1 - 0.00011 22.8 1.8 0.00011 22.8 1.8 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI44356.1 - 0.0016 18.7 0.7 0.0016 18.7 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KPI44356.1 - 0.055 13.5 1.7 0.13 12.3 1.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KPI44356.1 - 0.059 13.7 3.6 0.15 12.4 3.4 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KPI44356.1 - 0.15 12.7 9.2 0.35 11.5 1.4 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KPI44356.1 - 0.76 10.5 7.8 0.26 12.0 2.6 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger p450 PF00067.22 KPI44357.1 - 7.2e-61 206.3 0.0 6.3e-60 203.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KPI44358.1 - 6.5e-30 103.2 0.6 9.8e-30 102.7 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI44358.1 - 5.3e-15 55.5 0.0 8.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI44358.1 - 0.00017 21.1 0.0 0.00032 20.3 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Glyco_hydro_16 PF00722.21 KPI44359.1 - 1.2e-09 37.9 0.3 2.7e-09 36.7 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Nitroreductase PF00881.24 KPI44360.1 - 3e-08 33.9 0.6 7e-08 32.7 0.6 1.6 1 1 0 1 1 1 1 Nitroreductase family FAA_hydrolase PF01557.18 KPI44361.1 - 5.7e-66 222.3 0.0 7.6e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family La PF05383.17 KPI44362.1 - 5.8e-18 64.7 0.0 1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 La domain Fungal_trans_2 PF11951.8 KPI44363.1 - 0.0045 15.8 5.8 0.61 8.8 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 KPI44364.1 - 4e-29 101.5 0.0 5.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44364.1 - 4.5e-18 65.7 0.0 6.2e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44364.1 - 2.3e-10 40.7 0.0 3.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KPI44364.1 - 0.00082 18.6 0.0 0.0014 17.9 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein EMP24_GP25L PF01105.24 KPI44365.1 - 2.2e-41 141.8 0.0 2.8e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ZapB PF06005.12 KPI44365.1 - 0.034 14.6 0.4 0.057 13.9 0.4 1.2 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KPI44365.1 - 0.1 13.3 0.2 0.55 10.9 0.5 1.8 2 0 0 2 2 2 0 Initiation control protein YabA PIEZO PF15917.5 KPI44365.1 - 0.16 11.4 0.2 0.24 10.9 0.2 1.1 1 0 0 1 1 1 0 Piezo FAM183 PF14886.6 KPI44366.1 - 0.016 15.9 1.3 0.046 14.4 1.3 1.8 1 0 0 1 1 1 0 FAM183A and FAM183B related Cnn_1N PF07989.11 KPI44367.1 - 2.2e-20 72.6 16.6 4e-20 71.8 9.5 11.6 10 3 2 12 12 12 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KPI44367.1 - 1.2e-19 70.3 28.2 1.5e-16 60.4 17.6 10.9 12 1 1 13 13 13 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1664 PF07889.12 KPI44367.1 - 0.026 14.6 0.6 0.026 14.6 0.6 8.9 7 2 2 10 10 10 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 KPI44367.1 - 0.9 9.9 11.2 5.2 7.4 0.0 5.4 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Fungal_trans_2 PF11951.8 KPI44368.1 - 2.5e-08 33.2 5.0 9.9e-08 31.2 5.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KPI44369.1 - 3.3e-21 75.6 37.3 3.3e-21 75.6 37.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KPI44370.1 - 5.5e-31 107.5 0.0 7.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44370.1 - 2.3e-21 76.4 0.0 3.4e-21 75.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44370.1 - 5.1e-08 33.0 0.0 8.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI44370.1 - 0.00033 20.2 0.0 0.00086 18.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KPI44370.1 - 0.00076 18.7 0.0 0.00096 18.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KPI44370.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KPI44370.1 - 0.24 10.8 0.0 0.5 9.7 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltrn_RNA_3 PF02598.17 KPI44371.1 - 1.6e-106 356.0 0.0 1.8e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase CbiA PF01656.23 KPI44371.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain XPG_N PF00752.17 KPI44371.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain zf-C2H2 PF00096.26 KPI44373.1 - 0.042 14.3 3.8 0.042 14.3 3.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ras PF00071.22 KPI44375.1 - 2.1e-54 183.5 0.0 2.4e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI44375.1 - 1.7e-20 73.4 0.0 2.4e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI44375.1 - 5.3e-08 32.5 0.0 6.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FAD_binding_3 PF01494.19 KPI44376.1 - 3.5e-05 23.2 0.8 3.5e-05 23.2 0.8 2.4 2 1 0 2 2 2 1 FAD binding domain Rubredoxin_C PF18267.1 KPI44376.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain MutS_V PF00488.21 KPI44377.1 - 3.4e-55 187.0 0.1 1.1e-54 185.4 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KPI44377.1 - 7.8e-38 130.6 1.2 7.8e-38 130.6 1.2 2.4 4 0 0 4 4 4 1 MutS domain III MutS_II PF05188.17 KPI44377.1 - 3.2e-21 76.1 1.8 6.5e-21 75.0 0.1 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KPI44377.1 - 4.2e-17 62.3 1.5 4.2e-17 62.3 1.5 2.7 2 1 1 3 3 3 1 MutS family domain IV MutS_I PF01624.20 KPI44377.1 - 3.1e-13 50.0 0.0 4e-12 46.4 0.0 2.5 2 0 0 2 2 2 1 MutS domain I DUF4559 PF15112.6 KPI44377.1 - 0.96 9.1 11.3 0.64 9.6 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Sec1 PF00995.23 KPI44378.1 - 1.6e-131 440.4 0.0 2e-131 440.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.13 KPI44378.1 - 0.0014 18.6 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family B12-binding PF02310.19 KPI44378.1 - 0.15 12.1 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain Hydrolase PF00702.26 KPI44379.1 - 5.1e-10 40.0 0.0 1.8e-06 28.4 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KPI44379.1 - 1.1e-09 38.6 0.1 8e-08 32.6 0.1 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI44379.1 - 0.00026 21.0 0.4 0.00075 19.5 0.2 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KPI44379.1 - 0.0016 18.9 0.0 0.01 16.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KPI44379.1 - 0.043 13.4 0.2 0.18 11.4 0.0 2.0 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase Pkinase PF00069.25 KPI44380.1 - 1.1e-76 257.7 0.0 2.3e-62 210.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44380.1 - 2.5e-44 151.5 0.0 1.1e-42 146.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI44380.1 - 5.4e-11 42.3 0.1 8.3e-08 31.9 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KPI44380.1 - 6e-09 35.2 0.0 0.0052 15.6 0.0 3.2 3 0 0 3 3 3 2 Fungal protein kinase Kdo PF06293.14 KPI44380.1 - 1.6e-05 24.4 0.0 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KPI44380.1 - 5.1e-05 23.3 0.1 0.017 15.1 0.0 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KPI44380.1 - 0.05 13.2 0.1 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KPI44380.1 - 0.26 10.3 0.1 4.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DEAD PF00270.29 KPI44381.1 - 4.8e-17 62.3 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI44381.1 - 2e-14 54.0 0.0 2.4e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KPI44381.1 - 2.2e-08 34.4 0.0 6.7e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4407 PF14362.6 KPI44381.1 - 0.36 10.2 14.4 0.53 9.6 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GFA PF04828.14 KPI44382.1 - 0.018 15.4 0.1 0.049 14.0 0.0 1.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Pyr_redox_2 PF07992.14 KPI44383.1 - 1.6e-12 47.3 0.0 3.9e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI44383.1 - 6.3e-10 38.1 0.6 2.3e-08 32.9 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI44383.1 - 4.8e-06 26.0 0.0 0.061 12.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI44383.1 - 5.2e-06 25.8 0.0 0.0002 20.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI44383.1 - 3.2e-05 24.1 0.0 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI44383.1 - 0.021 14.8 0.0 4.5 7.2 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI44383.1 - 0.12 11.4 0.0 1.3 8.0 0.0 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein Pkinase PF00069.25 KPI44384.1 - 0.00068 19.1 0.0 0.0036 16.7 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Ribosomal_S27 PF01599.19 KPI44385.1 - 3.3e-26 91.2 3.5 3.3e-26 91.2 3.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 KPI44385.1 - 3.8e-19 68.2 0.1 7.6e-19 67.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPI44385.1 - 4.5e-08 32.8 0.0 9.1e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KPI44385.1 - 0.0075 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FA_desaturase PF00487.24 KPI44386.1 - 3.9e-28 99.0 17.3 7.1e-28 98.1 17.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KPI44386.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.31 KPI44387.1 - 6.2e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 KPI44389.1 - 0.028 13.5 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1800 PF08811.11 KPI44389.1 - 0.18 10.8 0.1 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) MRJP PF03022.16 KPI44390.1 - 5e-32 111.4 0.0 7e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein PIR PF00399.19 KPI44390.1 - 3.1e-06 26.6 6.2 7.7e-06 25.3 6.2 1.7 1 0 0 1 1 1 1 Yeast PIR protein repeat SGL PF08450.12 KPI44390.1 - 1.4e-05 24.8 0.1 4.7e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KPI44390.1 - 0.00068 19.5 0.3 0.0059 16.5 0.2 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat NHL PF01436.21 KPI44390.1 - 0.0091 16.0 1.7 6.5 7.0 0.0 4.0 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.11 KPI44390.1 - 0.29 11.5 2.2 89 3.9 0.0 4.2 4 0 0 4 4 4 0 Two component regulator propeller Fungal_trans PF04082.18 KPI44391.1 - 5.6e-17 61.6 0.5 5.6e-17 61.6 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 KPI44391.1 - 6.4e-15 55.3 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI44391.1 - 0.00091 20.3 0.0 0.0025 18.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI44391.1 - 0.0016 18.0 0.0 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KPI44391.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding RCS1 PF07326.11 KPI44391.1 - 0.068 13.1 0.3 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Pyr_redox PF00070.27 KPI44391.1 - 0.069 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI44391.1 - 0.086 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KPI44391.1 - 0.096 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BPL_LplA_LipB PF03099.19 KPI44392.1 - 1.5e-05 24.9 0.0 6.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ytp1 PF10355.9 KPI44393.1 - 2.3e-112 374.7 9.2 3.8e-112 374.0 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KPI44393.1 - 1.2e-27 95.7 9.4 1.2e-27 95.7 9.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Bax1-I PF01027.20 KPI44393.1 - 0.36 10.6 27.0 0.62 9.9 9.1 2.8 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF1129 PF06570.11 KPI44393.1 - 0.42 10.1 11.5 0.052 13.0 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sec7 PF01369.20 KPI44394.1 - 3.8e-26 91.9 0.0 7.4e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KPI44394.1 - 1.8e-16 60.5 0.0 6.9e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain ADH_zinc_N_2 PF13602.6 KPI44396.1 - 1.3e-17 65.0 0.0 6.5e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPI44396.1 - 5.3e-09 36.1 0.0 1.5e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI44396.1 - 0.007 16.2 0.1 0.054 13.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain LsmAD PF06741.13 KPI44398.1 - 9.5e-25 87.0 7.5 9.5e-25 87.0 7.5 1.8 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KPI44398.1 - 6.5e-14 51.8 0.0 1.8e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain SAD_SRA PF02182.17 KPI44399.1 - 1.7e-26 92.8 0.0 2.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain zf-MIZ PF02891.20 KPI44401.1 - 3.1e-09 36.5 0.6 5.5e-09 35.6 0.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PemK_toxin PF02452.17 KPI44401.1 - 0.0078 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system zf-Nse PF11789.8 KPI44401.1 - 0.014 15.2 0.1 0.031 14.1 0.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trehalase PF01204.18 KPI44403.1 - 1.2e-173 578.6 0.2 1.9e-173 578.0 0.2 1.3 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KPI44403.1 - 1e-12 47.5 1.2 1.7e-12 46.8 1.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GSIII_N PF12437.8 KPI44403.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal adh_short PF00106.25 KPI44404.1 - 2.3e-23 82.7 0.1 8.3e-23 80.9 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase GRIM-19 PF06212.12 KPI44404.1 - 2.6e-20 72.7 0.0 5.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 GRIM-19 protein adh_short_C2 PF13561.6 KPI44404.1 - 5.6e-18 65.4 0.1 1e-17 64.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44404.1 - 3.4e-06 27.1 0.2 6.9e-06 26.1 0.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI44404.1 - 0.0096 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KPI44404.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 14-3-3 PF00244.20 KPI44405.1 - 3.2e-105 350.5 7.6 3.9e-105 350.3 7.6 1.1 1 0 0 1 1 1 1 14-3-3 protein TerB PF05099.13 KPI44405.1 - 0.01 15.8 0.2 0.032 14.2 0.2 1.8 1 0 0 1 1 1 0 Tellurite resistance protein TerB KIX_2 PF16987.5 KPI44405.1 - 0.027 14.5 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 KIX domain TPR_12 PF13424.6 KPI44405.1 - 0.085 13.2 1.6 0.41 11.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGAP PF00620.27 KPI44406.1 - 2e-46 157.6 0.0 4.5e-46 156.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KPI44406.1 - 1.9e-11 44.1 2.7 3.7e-11 43.1 0.2 2.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 KPI44406.1 - 0.051 12.9 8.7 0.21 10.9 9.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) T3SSipB PF16535.5 KPI44406.1 - 0.22 12.0 5.7 0.55 10.7 5.7 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF745 PF05335.13 KPI44406.1 - 1 9.0 14.1 0.029 14.1 2.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) OmpH PF03938.14 KPI44406.1 - 1.3 9.3 11.0 5.8 7.3 10.4 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 KPI44406.1 - 6.8 5.5 4.9 14 4.5 2.4 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Gaa1 PF04114.14 KPI44409.1 - 3.5e-154 514.5 0.4 4.4e-154 514.2 0.4 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component TRAM_LAG1_CLN8 PF03798.16 KPI44410.1 - 1.1e-39 136.2 18.4 6.6e-38 130.4 12.8 2.3 1 1 1 2 2 2 2 TLC domain DUF2474 PF10617.9 KPI44410.1 - 0.064 13.1 0.8 0.74 9.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) PAP2_3 PF14378.6 KPI44412.1 - 7.8e-21 74.6 19.2 2.9e-17 63.0 9.0 2.8 4 0 0 4 4 4 2 PAP2 superfamily XPG_I PF00867.18 KPI44413.1 - 1.8e-22 79.5 0.1 3.9e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KPI44413.1 - 2.6e-20 72.8 0.0 5.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KPI44413.1 - 5.7e-05 22.7 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KPI44413.1 - 0.062 13.9 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold adh_short PF00106.25 KPI44414.1 - 3.4e-16 59.3 0.0 7.3e-16 58.2 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44414.1 - 8.2e-09 35.4 0.0 1.4e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Csm1_B PF18211.1 KPI44414.1 - 0.0031 17.3 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 Csm1 subunit domain B KR PF08659.10 KPI44414.1 - 0.0045 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain APH PF01636.23 KPI44416.1 - 1.5e-21 77.5 0.0 2.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPI44416.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KPI44416.1 - 0.083 12.1 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase MFMR PF07777.11 KPI44418.1 - 0.069 13.6 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 G-box binding protein MFMR SUR7 PF06687.12 KPI44419.1 - 4.8e-39 134.2 2.8 5.7e-39 133.9 2.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KPI44419.1 - 0.00021 20.8 1.0 0.00034 20.1 1.0 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.11 KPI44419.1 - 0.0059 16.5 8.8 0.01 15.7 8.8 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KPI44419.1 - 0.0096 15.8 6.1 0.02 14.8 6.1 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF373 PF04123.13 KPI44419.1 - 0.045 13.2 0.7 0.076 12.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF805 PF05656.14 KPI44419.1 - 0.89 10.0 4.3 1.1 9.8 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Fungal_trans PF04082.18 KPI44420.1 - 1.5e-28 99.5 0.5 2.2e-28 99.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KPI44421.1 - 1.4e-44 152.5 0.0 2.1e-44 151.9 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_M16 PF00675.20 KPI44422.1 - 1.7e-56 190.4 0.0 1.5e-55 187.3 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KPI44422.1 - 3e-40 138.2 0.0 5.3e-39 134.1 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M20 PF01546.28 KPI44423.1 - 2.8e-32 112.1 0.0 3.9e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KPI44423.1 - 1.5e-14 53.8 0.0 2.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KPI44423.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Chromo PF00385.24 KPI44424.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain p450 PF00067.22 KPI44426.1 - 7e-14 51.4 0.1 8.7e-12 44.5 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 HORMA PF02301.18 KPI44427.1 - 7.8e-34 117.1 0.1 9.1e-34 116.9 0.1 1.0 1 0 0 1 1 1 1 HORMA domain Alba PF01918.21 KPI44427.1 - 0.03 14.2 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Alba TAF PF02969.17 KPI44427.1 - 0.097 12.9 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3437 PF11919.8 KPI44427.1 - 0.13 12.2 0.3 0.26 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Pup PF05639.11 KPI44427.1 - 0.26 12.2 3.5 0.6 11.1 2.1 2.1 2 0 0 2 2 2 0 Pup-like protein DUF1917 PF08939.10 KPI44428.1 - 7.7e-68 229.2 0.2 1.3e-67 228.4 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) V-SNARE_C PF12352.8 KPI44428.1 - 0.038 14.3 0.3 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Iso_dh PF00180.20 KPI44430.1 - 2.9e-123 411.4 0.0 3.3e-123 411.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RabGAP-TBC PF00566.18 KPI44431.1 - 1.6e-34 119.5 0.0 2.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA-synt_1 PF00133.22 KPI44432.1 - 1.4e-48 165.6 0.0 1.4e-29 102.9 0.0 5.6 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KPI44432.1 - 3.7e-36 124.4 0.0 5.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KPI44432.1 - 1.4e-26 93.1 0.0 6e-20 71.4 0.0 4.1 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KPI44432.1 - 3.2e-09 36.9 0.0 7.7e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KPI44432.1 - 0.004 16.5 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Lar_restr_allev PF14354.6 KPI44432.1 - 0.012 15.9 0.1 5.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KPI44432.1 - 0.15 12.2 1.5 1.7 8.8 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain adh_short PF00106.25 KPI44433.1 - 2.3e-33 115.3 0.0 3.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44433.1 - 3e-27 95.7 0.0 4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI44433.1 - 6.3e-05 23.0 0.3 0.00017 21.5 0.1 1.7 2 0 0 2 2 2 1 KR domain AdoHcyase_NAD PF00670.21 KPI44433.1 - 0.025 14.6 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.16 KPI44434.1 - 3.6e-28 98.5 44.0 5.1e-28 98.0 44.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Kri1_C PF12936.7 KPI44435.1 - 2.2e-30 104.7 0.7 2.2e-30 104.7 0.7 4.5 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 KPI44435.1 - 1.8e-28 99.1 19.2 1.8e-28 99.1 19.2 4.7 5 2 0 5 5 5 1 KRI1-like family CRISPR_Cse2 PF09485.10 KPI44435.1 - 1.8 9.1 8.8 0.28 11.7 4.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) GPP34 PF05719.11 KPI44436.1 - 8.4e-67 225.1 0.1 1.1e-66 224.8 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HTH_23 PF13384.6 KPI44438.1 - 0.037 13.8 3.9 4.9 7.1 0.8 3.3 2 1 0 2 2 2 0 Homeodomain-like domain HTH_AraC PF00165.23 KPI44438.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Hamartin PF04388.12 KPI44439.1 - 0.069 11.8 3.0 0.064 11.9 3.0 1.1 1 0 0 1 1 1 0 Hamartin protein HLH PF00010.26 KPI44439.1 - 0.65 10.0 5.6 0.13 12.2 0.6 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain WW PF00397.26 KPI44441.1 - 2e-09 37.4 2.1 6.9e-09 35.6 2.1 2.0 1 0 0 1 1 1 1 WW domain DUF1192 PF06698.11 KPI44441.1 - 0.092 12.8 0.4 0.21 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CENP-B_dimeris PF09026.10 KPI44441.1 - 0.2 12.1 6.1 0.43 11.0 6.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SIP1 PF04938.12 KPI44441.1 - 0.27 10.9 4.2 0.1 12.3 1.1 1.8 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-MYST PF17772.1 KPI44441.1 - 3.2 7.5 8.1 0.095 12.3 1.0 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain FTHFS PF01268.19 KPI44442.1 - 9.8e-233 773.4 0.0 6.5e-231 767.3 0.0 2.2 1 1 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KPI44442.1 - 2.8e-69 231.5 1.5 2.8e-69 231.5 1.5 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KPI44442.1 - 3.4e-39 133.7 0.7 6.9e-39 132.7 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 KPI44442.1 - 0.0031 17.1 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain OCD_Mu_crystall PF02423.15 KPI44442.1 - 0.0061 15.5 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family RsgA_GTPase PF03193.16 KPI44442.1 - 0.15 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DASH_Spc19 PF08287.11 KPI44443.1 - 8e-47 159.0 0.6 1e-46 158.7 0.6 1.2 1 0 0 1 1 1 1 Spc19 Syntaxin_2 PF14523.6 KPI44443.1 - 0.015 15.6 3.2 0.19 12.1 0.6 2.5 1 1 1 2 2 2 0 Syntaxin-like protein LPD30 PF18850.1 KPI44443.1 - 0.14 11.9 0.1 0.28 11.0 0.0 1.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 Scs3p PF10261.9 KPI44444.1 - 2.3e-22 79.7 3.2 2.8e-22 79.4 3.2 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM HlyIII PF03006.20 KPI44446.1 - 1.1e-48 165.9 9.1 1.4e-48 165.6 9.1 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3325 PF11804.8 KPI44446.1 - 0.41 10.8 8.8 0.18 12.0 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) KH_1 PF00013.29 KPI44447.1 - 1.9e-42 142.9 8.8 3.9e-17 61.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KPI44447.1 - 1.6e-10 40.6 10.2 0.0073 16.1 0.8 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 KPI44447.1 - 1.2e-09 37.9 5.3 0.0078 16.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KPI44447.1 - 0.00015 21.8 7.4 0.11 12.6 0.2 3.3 3 0 0 3 3 3 3 NusA-like KH domain SLATT_fungal PF18142.1 KPI44448.1 - 1.5e-30 105.6 0.4 2.7e-30 104.8 0.4 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_5 PF18160.1 KPI44448.1 - 1.6e-06 27.6 0.0 2.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 DUF4231 PF14015.6 KPI44448.1 - 0.036 14.5 0.2 0.061 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) SLATT_1 PF18181.1 KPI44448.1 - 0.058 13.3 2.0 0.089 12.7 0.6 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Sec2p PF06428.11 KPI44448.1 - 0.067 13.2 0.6 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SPW PF03779.14 KPI44448.1 - 0.25 10.9 3.7 0.26 10.9 2.7 1.6 1 1 0 1 1 1 0 SPW repeat VIT1 PF01988.19 KPI44448.1 - 2.1 8.2 8.5 1.8 8.4 3.0 2.3 1 1 1 2 2 2 0 VIT family Vac_ImportDeg PF09783.9 KPI44449.1 - 1.1e-28 100.1 0.0 4.8e-28 98.0 0.0 1.9 1 1 0 1 1 1 1 Vacuolar import and degradation protein Tfb2 PF03849.14 KPI44451.1 - 6.2e-119 397.1 0.0 8e-119 396.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KPI44451.1 - 7e-23 80.8 0.7 2.3e-22 79.2 0.9 1.8 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KPI44451.1 - 0.00039 20.6 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT_3 PF13622.6 KPI44452.1 - 7e-41 141.1 0.1 8.9e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KPI44452.1 - 0.001 18.9 0.1 0.0027 17.6 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA thioesterase DUF5102 PF17104.5 KPI44453.1 - 6.5e-98 328.3 6.1 1e-97 327.7 6.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Clathrin_bdg PF15045.6 KPI44453.1 - 0.13 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Fungal_trans PF04082.18 KPI44454.1 - 1.5e-23 83.2 0.1 2.3e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KPI44454.1 - 2e-17 63.5 0.0 1.2e-12 47.8 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KPI44454.1 - 1.1e-06 28.5 0.9 0.0064 16.1 1.7 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI44454.1 - 1.7e-06 27.4 1.1 1.3e-05 24.5 1.2 2.0 1 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KPI44454.1 - 1.9e-05 24.8 0.1 6.4e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI44454.1 - 0.0019 17.5 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KPI44454.1 - 0.005 16.9 0.5 0.013 15.6 0.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HI0933_like PF03486.14 KPI44454.1 - 0.0077 15.0 0.1 0.012 14.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KPI44454.1 - 0.0078 15.3 0.2 0.031 13.3 0.2 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KPI44454.1 - 0.011 16.3 0.2 0.022 15.3 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI44454.1 - 0.014 14.8 0.5 0.014 14.8 0.5 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KPI44454.1 - 0.028 13.5 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI44454.1 - 0.16 11.2 3.0 0.25 10.6 3.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KPI44454.1 - 0.22 11.4 0.2 0.35 10.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KPI44455.1 - 8e-92 308.2 0.0 9.9e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI44455.1 - 5.5e-07 29.5 0.3 0.0038 16.9 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI44455.1 - 0.0027 17.0 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI44455.1 - 0.0043 17.2 0.1 0.012 15.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI44455.1 - 0.042 13.1 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI44455.1 - 0.042 12.9 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 KPI44455.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 KPI44455.1 - 0.051 12.7 0.5 0.089 11.9 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KPI44455.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 KPI44455.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArsA_ATPase PF02374.15 KPI44457.1 - 2.2e-95 319.4 0.0 2.5e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KPI44457.1 - 0.00038 20.4 0.0 0.0067 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain BRE1 PF08647.11 KPI44458.1 - 1.2e-23 83.0 17.1 1.2e-23 83.0 17.1 6.9 5 1 1 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KPI44458.1 - 1.3e-06 28.1 9.3 2.3e-06 27.3 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI44458.1 - 1.7e-06 27.7 7.9 3.6e-06 26.7 7.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KPI44458.1 - 9.7e-06 25.4 11.7 1.9e-05 24.5 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI44458.1 - 6.8e-05 22.8 10.2 0.00012 21.9 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPI44458.1 - 0.00018 21.2 10.7 0.00036 20.3 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI44458.1 - 0.00057 20.2 9.7 0.0011 19.2 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI44458.1 - 0.00081 19.4 6.0 0.0017 18.4 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PRKG1_interact PF15898.5 KPI44458.1 - 0.0081 17.0 8.2 0.0081 17.0 8.2 7.2 2 2 4 6 6 5 1 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 KPI44458.1 - 0.009 15.9 14.1 0.009 15.9 14.1 6.1 1 1 2 4 4 1 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KPI44458.1 - 0.047 14.2 89.9 0.12 12.9 12.2 6.8 2 1 3 5 5 3 0 Apg6 coiled-coil region Rad50_zn_hook PF04423.14 KPI44458.1 - 0.13 12.2 0.1 0.13 12.2 0.1 4.9 5 0 0 5 5 4 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KPI44458.1 - 0.14 11.9 5.3 0.41 10.5 5.3 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 KPI44458.1 - 0.16 12.5 0.2 0.16 12.5 0.2 1.9 2 0 0 2 2 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_5 PF17121.5 KPI44458.1 - 0.21 11.5 4.8 0.41 10.6 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPI44458.1 - 0.33 11.2 7.9 0.7 10.1 7.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Filament PF00038.21 KPI44458.1 - 1.9 8.0 77.4 6.1 6.3 0.3 5.0 2 1 1 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 KPI44458.1 - 4.5 7.5 88.6 0.13 12.5 27.0 5.2 4 1 0 4 4 3 0 Autophagy protein 16 (ATG16) CCDC92 PF14916.6 KPI44458.1 - 5 7.0 17.8 1.5 8.6 0.1 5.6 5 0 0 5 5 5 0 Coiled-coil domain of unknown function DUF3886 PF13025.6 KPI44459.1 - 0.17 12.1 4.2 0.35 11.1 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF2370 PF10176.9 KPI44460.1 - 3.7e-85 285.2 0.0 5.7e-85 284.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 KPI44460.1 - 0.26 11.3 1.3 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) ELYS PF13934.6 KPI44462.1 - 5.4e-53 180.2 6.4 6.5e-53 180.0 6.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF4274 PF14096.6 KPI44462.1 - 0.0041 17.0 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4274) DPM3 PF08285.11 KPI44463.1 - 7.2 6.9 7.4 0.26 11.5 0.2 2.3 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PAP2 PF01569.21 KPI44464.1 - 9.9e-24 83.6 1.0 9.9e-24 83.6 1.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily Zip PF02535.22 KPI44466.1 - 2.2e-52 178.4 2.4 5.2e-52 177.1 2.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DAP10 PF07213.11 KPI44466.1 - 0.58 10.2 2.8 0.56 10.2 0.4 2.2 2 0 0 2 2 2 0 DAP10 membrane protein OppC_N PF12911.7 KPI44466.1 - 3.6 7.6 12.1 4.8 7.2 0.1 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C BTB PF00651.31 KPI44467.1 - 2.2e-11 43.9 0.1 1.3e-10 41.5 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain FMO-like PF00743.19 KPI44468.1 - 2.2e-53 181.5 0.0 4.5e-53 180.5 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KPI44468.1 - 1.3e-13 50.9 0.0 1.3e-09 37.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI44468.1 - 7.3e-07 28.7 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI44468.1 - 5.1e-05 22.6 0.0 0.00012 21.3 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KPI44468.1 - 0.0073 16.5 0.1 0.024 14.8 0.0 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI44468.1 - 0.015 15.3 0.3 0.51 10.3 0.0 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding COX5A PF02284.16 KPI44469.1 - 3.3e-41 139.5 0.1 4.6e-41 139.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va GMC_oxred_N PF00732.19 KPI44470.1 - 5e-59 200.1 0.0 7e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI44470.1 - 2.9e-37 128.4 0.0 5.7e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KPI44470.1 - 0.00045 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KPI44470.1 - 0.00095 19.3 0.0 0.0031 17.7 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KPI44470.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KPI44470.1 - 0.0017 17.5 0.1 0.035 13.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KPI44470.1 - 0.018 14.3 0.5 3.6 6.8 0.2 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI44470.1 - 0.068 12.7 0.1 0.29 10.7 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KPI44470.1 - 0.086 13.1 0.2 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KPI44470.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MACPF PF01823.19 KPI44471.1 - 4.5e-15 56.3 4.7 9.2e-15 55.3 4.0 1.9 1 1 1 2 2 2 2 MAC/Perforin domain MFS_2 PF13347.6 KPI44472.1 - 9.6e-07 27.7 11.6 4.6e-06 25.4 7.0 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 KPI44472.1 - 0.0024 17.0 3.1 0.0024 17.0 3.1 1.6 2 0 0 2 2 2 1 PUCC protein DSPc PF00782.20 KPI44473.1 - 1.8e-20 73.1 0.0 3.6e-18 65.7 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ArAE_2_N PF10337.9 KPI44474.1 - 2.4e-27 96.1 10.1 8.7e-26 91.0 9.9 3.1 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KPI44474.1 - 2.1e-13 50.5 15.0 2.1e-13 50.5 15.0 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KPI44474.1 - 2.4e-10 40.6 0.0 4.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 UcrQ PF02939.16 KPI44474.1 - 1.6 8.7 4.6 18 5.3 0.4 3.4 3 0 0 3 3 3 0 UcrQ family Fungal_trans_2 PF11951.8 KPI44475.1 - 0.0032 16.3 0.8 0.06 12.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain CLTH PF10607.9 KPI44476.1 - 6.8e-27 94.2 0.2 1.1e-26 93.5 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KPI44476.1 - 8.5e-08 32.1 0.2 1.6e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPI44476.1 - 0.00069 19.5 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 KPI44476.1 - 0.00073 19.0 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KPI44476.1 - 0.0051 17.1 0.4 0.0088 16.4 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI44476.1 - 0.008 16.0 1.1 0.015 15.1 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KPI44476.1 - 0.03 14.5 0.9 0.059 13.5 0.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KPI44476.1 - 0.035 14.0 0.5 0.063 13.2 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI44476.1 - 0.045 13.6 0.5 0.077 12.9 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI44476.1 - 0.072 13.0 0.8 0.14 12.1 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LisH PF08513.11 KPI44476.1 - 0.088 12.8 1.4 0.3 11.1 0.1 2.3 2 0 0 2 2 2 0 LisH MFS_1 PF07690.16 KPI44477.1 - 6.9e-22 77.9 40.2 1.2e-19 70.4 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KPI44477.1 - 0.045 12.1 2.8 0.044 12.1 1.6 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KPI44478.1 - 3.5e-19 69.0 34.3 9.1e-14 51.1 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44478.1 - 3.7e-10 39.3 20.2 2.3e-09 36.7 2.8 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Ni_hydr_CYTB PF01292.20 KPI44478.1 - 0.00038 20.1 1.3 0.00038 20.1 1.3 2.2 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Tyr-DNA_phospho PF06087.12 KPI44479.1 - 9e-49 166.5 0.0 3.2e-48 164.7 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KPI44479.1 - 0.00052 19.8 8.3 0.0074 16.1 1.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 KPI44479.1 - 0.095 12.6 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain COesterase PF00135.28 KPI44480.1 - 2.8e-80 270.6 0.0 1.1e-71 242.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI44480.1 - 9.3e-07 28.9 0.4 2.2e-06 27.7 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KPI44480.1 - 0.052 13.0 0.1 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase zf-C2H2_jaz PF12171.8 KPI44481.1 - 4.4e-09 36.4 0.6 4.4e-09 36.4 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI44481.1 - 1.3e-08 34.9 0.7 1.3e-08 34.9 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KPI44481.1 - 0.0012 19.0 0.3 0.003 17.6 0.3 1.6 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.26 KPI44481.1 - 0.056 13.9 0.4 0.1 13.1 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KPI44481.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Acatn PF13000.7 KPI44482.1 - 2.4e-134 448.8 21.7 2e-79 267.5 9.2 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Peptidase_C65 PF10275.9 KPI44483.1 - 3.9e-45 154.2 0.0 8.7e-32 110.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain Myb_DNA-bind_7 PF15963.5 KPI44483.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Myb DNA-binding like KOW PF00467.29 KPI44484.1 - 0.12 12.3 0.8 0.27 11.3 0.8 1.6 1 0 0 1 1 1 0 KOW motif Kinesin PF00225.23 KPI44487.1 - 1.9e-84 283.4 0.5 1.9e-84 283.4 0.5 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KPI44487.1 - 1.7e-24 86.5 0.1 3e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding HHH_5 PF14520.6 KPI44487.1 - 0.01 16.4 0.4 0.16 12.6 0.6 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 KPI44487.1 - 0.03 14.2 0.2 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif PRKG1_interact PF15898.5 KPI44487.1 - 0.36 11.8 7.4 0.25 12.3 4.5 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PP28 PF10252.9 KPI44489.1 - 6.6e-26 90.6 21.8 6.6e-26 90.6 21.8 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 EI24 PF07264.11 KPI44490.1 - 1.2e-13 51.7 0.1 1.9e-13 51.1 0.1 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF5357 PF17310.2 KPI44490.1 - 0.081 11.5 0.5 0.12 10.9 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) CBS PF00571.28 KPI44491.1 - 1.7e-15 57.2 9.2 6.8e-05 23.2 0.0 5.2 5 0 0 5 5 5 4 CBS domain NAD4L PF06235.11 KPI44492.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Glyco_hydro_3 PF00933.21 KPI44493.1 - 6.6e-30 104.6 0.0 1.1e-29 103.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KPI44493.1 - 3.3e-28 99.0 0.0 6.1e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KPI44493.1 - 8.4e-07 29.0 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.25 KPI44494.1 - 4.1e-68 229.6 0.0 6e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44494.1 - 7.9e-39 133.5 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KPI44494.1 - 7.3e-14 51.3 0.1 1.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KPI44494.1 - 2.1e-06 26.9 0.0 3.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPI44494.1 - 3.3e-06 26.6 0.1 6.7e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KPI44494.1 - 8.6e-05 22.0 0.0 0.00059 19.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KPI44494.1 - 0.0011 18.9 0.2 0.26 11.2 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KPI44494.1 - 0.095 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KPI44494.1 - 0.19 11.3 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family MAM33 PF02330.16 KPI44495.1 - 5.6e-51 173.5 0.5 7.3e-51 173.1 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Methyltransf_23 PF13489.6 KPI44500.1 - 3.1e-17 62.9 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI44500.1 - 2.2e-09 37.9 0.0 5.3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI44500.1 - 1.4e-06 28.2 0.0 9e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI44500.1 - 0.00015 22.3 0.0 0.00029 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KPI44500.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KPI44500.1 - 0.0093 15.5 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KPI44500.1 - 0.024 15.3 0.0 0.18 12.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KPI44500.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Zn_clus PF00172.18 KPI44501.1 - 4.5e-08 33.1 9.6 7.8e-08 32.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5106 PF17127.4 KPI44501.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) CorA PF01544.18 KPI44502.1 - 1.1e-05 24.9 7.2 4.5e-05 22.9 7.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FapA PF03961.13 KPI44502.1 - 0.17 10.5 0.9 0.24 9.9 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GTP_EFTU PF00009.27 KPI44503.1 - 3e-48 163.9 0.0 4.9e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KPI44503.1 - 5.3e-40 135.9 4.1 8.6e-40 135.2 4.1 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KPI44503.1 - 4.3e-21 74.7 0.0 7.5e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KPI44503.1 - 1.1e-05 25.7 0.0 2.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPI44503.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KPI44503.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 KPI44503.1 - 0.0017 18.4 0.0 0.0048 16.9 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KPI44503.1 - 0.0045 16.8 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 KPI44503.1 - 0.0071 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Mago_nashi PF02792.14 KPI44503.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Mago nashi protein ChAPs PF09295.10 KPI44505.1 - 6.4e-150 499.6 0.0 9.3e-150 499.0 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KPI44505.1 - 7e-05 23.3 1.2 0.13 13.2 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KPI44505.1 - 0.00088 19.3 0.3 2.4 8.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KPI44505.1 - 0.001 19.0 3.2 0.13 12.4 1.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KPI44505.1 - 0.0019 17.5 6.9 0.11 11.7 0.5 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPI44505.1 - 0.015 15.8 1.0 3.6 8.2 0.0 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KPI44505.1 - 0.016 15.0 1.7 4.2 7.3 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KPI44505.1 - 0.033 14.5 1.2 3.2 8.1 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1824 PF08854.10 KPI44505.1 - 0.095 12.6 0.1 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) YejG PF13989.6 KPI44505.1 - 0.16 12.4 0.1 0.6 10.6 0.0 1.9 2 0 0 2 2 2 0 YejG-like protein 14-3-3 PF00244.20 KPI44507.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 14-3-3 protein Med3 PF11593.8 KPI44507.1 - 0.12 11.5 10.8 0.21 10.7 10.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LYRIC PF15686.5 KPI44507.1 - 7.6 6.0 13.0 11 5.5 13.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family YccV-like PF08755.11 KPI44508.1 - 2.1e-23 82.7 0.2 1.8e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KPI44508.1 - 1.8e-09 37.3 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KPI44508.1 - 3.5e-09 36.4 0.7 8e-09 35.3 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI44508.1 - 2.9e-06 27.0 0.0 6.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KPI44508.1 - 0.00063 20.2 0.4 0.0013 19.3 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A IBR PF01485.21 KPI44510.1 - 2.4e-11 43.7 44.8 1.5e-06 28.3 9.4 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DUF2158 PF09926.9 KPI44510.1 - 0.036 13.8 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) SUIM_assoc PF16619.5 KPI44510.1 - 0.29 11.3 3.3 0.54 10.4 0.9 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ferric_reduct PF01794.19 KPI44511.1 - 3e-18 66.2 4.1 3e-18 66.2 4.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KPI44511.1 - 4e-15 56.3 0.0 1.1e-09 38.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI44511.1 - 4.8e-13 49.1 0.0 3.7e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Acetyltransf_1 PF00583.25 KPI44512.1 - 1.8e-11 44.3 0.0 2.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI44512.1 - 2.2e-09 37.3 0.0 3.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI44512.1 - 4.4e-07 30.2 0.0 7.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KPI44512.1 - 0.0016 19.1 0.0 0.002 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI44512.1 - 0.016 15.3 0.0 0.054 13.6 0.1 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KPI44512.1 - 0.026 15.2 0.0 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI44512.1 - 0.026 14.5 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 KPI44512.1 - 0.037 13.5 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KPI44512.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Myb_DNA-bind_7 PF15963.5 KPI44514.1 - 5.5e-17 61.4 0.1 1.5e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KPI44514.1 - 0.0042 17.2 0.2 0.012 15.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain AMP-binding PF00501.28 KPI44515.1 - 3e-22 78.8 0.0 6.9e-21 74.3 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme Oxysterol_BP PF01237.18 KPI44516.1 - 5e-52 177.0 0.4 9.2e-50 169.5 0.4 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_M99 PF17033.5 KPI44517.1 - 0.07 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Mo25 PF08569.11 KPI44518.1 - 4.7e-26 91.9 0.0 5.7e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Mo25-like LysM PF01476.20 KPI44519.1 - 6e-09 35.8 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 LysM domain Big_3_5 PF16640.5 KPI44519.1 - 0.13 12.4 5.4 0.28 11.4 5.4 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Fructosamin_kin PF03881.14 KPI44520.1 - 1.7e-66 224.4 0.0 5.2e-66 222.8 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KPI44520.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KPI44520.1 - 0.027 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DEAD PF00270.29 KPI44521.1 - 9e-42 142.8 0.0 2.5e-41 141.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI44521.1 - 1.4e-24 86.6 0.0 4.9e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KPI44521.1 - 2.1e-20 72.7 0.6 3.6e-20 71.9 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KPI44521.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KPI44521.1 - 0.00032 20.0 0.0 0.00067 18.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PHC2_SAM_assoc PF16616.5 KPI44521.1 - 0.19 12.6 10.9 0.37 11.6 10.9 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Spore_coat_CotO PF14153.6 KPI44521.1 - 5.8 6.8 10.6 9.8 6.1 10.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Brix PF04427.18 KPI44522.1 - 3.8e-42 144.6 0.1 5.4e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain Cytochrom_B561 PF03188.16 KPI44523.1 - 1.7e-07 31.4 15.4 3.3e-07 30.5 15.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KPI44523.1 - 0.00042 20.1 0.1 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Peptidase_A24 PF01478.18 KPI44523.1 - 3.4 8.1 7.6 0.62 10.5 1.9 2.3 2 0 0 2 2 2 0 Type IV leader peptidase family Mpp10 PF04006.12 KPI44524.1 - 1.4e-100 337.5 44.9 3.4e-100 336.3 44.9 1.6 1 1 0 1 1 1 1 Mpp10 protein Fungal_trans PF04082.18 KPI44525.1 - 1.3e-16 60.4 2.4 3.4e-16 59.1 2.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI44525.1 - 6.9e-05 22.9 8.2 6.9e-05 22.9 8.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KPI44525.1 - 0.00011 22.7 3.7 0.00047 20.8 3.7 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI44525.1 - 0.00046 20.5 3.8 0.0017 18.7 3.8 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KPI44525.1 - 0.017 15.4 0.8 0.057 13.7 0.8 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KPI44525.1 - 0.027 14.5 2.1 0.061 13.3 2.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 KPI44525.1 - 0.086 13.2 0.6 0.21 11.9 0.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KPI44525.1 - 0.22 12.0 0.9 0.58 10.6 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Pkinase PF00069.25 KPI44526.1 - 9.5e-40 136.6 0.0 1.5e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44526.1 - 3.2e-29 102.0 0.0 4.5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI44526.1 - 0.0006 19.8 1.7 0.13 12.2 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI44526.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Annexin PF00191.20 KPI44527.1 - 7.8e-16 57.9 0.7 4.2e-05 23.5 0.0 4.3 4 0 0 4 4 4 3 Annexin ArgoL1 PF08699.10 KPI44527.1 - 0.19 11.4 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Argonaute linker 1 domain G-patch PF01585.23 KPI44528.1 - 5.8e-09 35.7 1.5 5.8e-09 35.7 1.5 2.1 1 1 1 2 2 2 1 G-patch domain zf-RanBP PF00641.18 KPI44528.1 - 1e-08 34.3 4.1 1.8e-08 33.5 4.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KPI44528.1 - 2.3e-08 33.8 0.4 9.9e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KPI44528.1 - 0.00021 21.3 0.7 0.00056 19.9 0.4 1.9 1 1 0 1 1 1 1 G-patch domain RED_N PF07808.13 KPI44528.1 - 0.032 13.8 0.1 0.032 13.8 0.1 2.3 3 0 0 3 3 3 0 RED-like protein N-terminal region MFS_1 PF07690.16 KPI44529.1 - 1e-18 67.4 39.1 1e-18 67.4 39.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44529.1 - 1.3e-08 34.2 7.1 1.3e-08 34.2 7.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter GATA PF00320.27 KPI44530.1 - 2.4e-10 39.9 7.8 5.8e-10 38.6 7.8 1.7 1 0 0 1 1 1 1 GATA zinc finger GRAM PF02893.20 KPI44531.1 - 7e-31 106.5 1.3 1.4e-18 66.8 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KPI44531.1 - 6.3e-30 104.0 0.0 1.4e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KPI44531.1 - 4.4e-14 52.9 0.0 3.6e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KPI44531.1 - 1.9e-05 25.0 0.2 8.1e-05 23.0 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KPI44531.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 KPI44531.1 - 0.00034 19.5 0.0 0.00057 18.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 KPI44531.1 - 0.0024 18.1 0.0 0.0093 16.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Formin_GBD_N PF18382.1 KPI44531.1 - 0.19 12.2 0.2 0.52 10.8 0.2 1.7 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain Rhomboid PF01694.22 KPI44532.1 - 5.7e-15 55.6 8.1 5.7e-15 55.6 8.1 1.9 2 1 1 3 3 3 1 Rhomboid family Ig_3 PF13927.6 KPI44533.1 - 0.0024 18.4 0.0 0.33 11.6 0.0 4.0 4 1 0 4 4 4 1 Immunoglobulin domain DUF5011 PF16403.5 KPI44533.1 - 0.0031 17.6 0.1 0.029 14.5 0.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF5011) DUF1918 PF08940.11 KPI44533.1 - 0.024 14.2 3.3 1.7 8.3 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) I-set PF07679.16 KPI44533.1 - 0.15 12.2 0.0 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin I-set domain adh_short_C2 PF13561.6 KPI44534.1 - 4.4e-25 88.6 0.5 9.6e-25 87.5 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44534.1 - 6.1e-17 61.7 0.0 9.3e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI44534.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain CybS PF05328.12 KPI44536.1 - 1.4e-46 157.5 0.0 1.6e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Actin PF00022.19 KPI44538.1 - 1.6e-86 290.5 0.0 1.7e-85 287.1 0.0 1.9 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 KPI44538.1 - 0.098 11.7 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Cupin_1 PF00190.22 KPI44539.1 - 7.9e-21 74.2 0.4 1.3e-20 73.5 0.4 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KPI44539.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Mannosyl_trans4 PF15971.5 KPI44539.1 - 0.13 12.1 0.8 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase Mog1 PF04603.12 KPI44540.1 - 7.5e-26 91.1 0.1 1.5e-25 90.2 0.1 1.5 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Aa_trans PF01490.18 KPI44541.1 - 6.5e-28 97.6 25.5 8.3e-28 97.2 25.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2101 PF09874.9 KPI44541.1 - 0.091 12.5 0.1 0.091 12.5 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Flavin_Reduct PF01613.18 KPI44542.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Flavin reductase like domain DUF5102 PF17104.5 KPI44543.1 - 0.14 12.1 0.3 0.14 12.1 0.3 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF5102) zf-PHD-like PF15446.6 KPI44544.1 - 2.6e-65 219.2 11.6 6.9e-65 217.8 11.6 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KPI44544.1 - 3.4e-51 174.0 0.4 5.5e-51 173.3 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KPI44544.1 - 4.7e-24 84.0 2.7 6.1e-24 83.6 0.9 2.2 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KPI44544.1 - 4.5e-16 59.2 0.0 1.2e-15 57.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KPI44544.1 - 5.2e-11 42.3 0.7 1.4e-10 40.8 0.7 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KPI44544.1 - 4.4e-07 30.1 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KPI44544.1 - 1.4e-06 28.1 2.0 0.0021 17.9 1.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KPI44544.1 - 7.3e-06 25.8 3.9 7.3e-06 25.8 3.9 3.7 3 2 0 3 3 3 1 PHD-finger DUF1087 PF06465.13 KPI44544.1 - 0.00017 21.5 0.0 0.00064 19.7 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) DEAD_2 PF06733.15 KPI44544.1 - 0.018 14.7 0.1 0.051 13.2 0.1 1.7 1 0 0 1 1 1 0 DEAD_2 Prok-RING_1 PF14446.6 KPI44544.1 - 0.02 14.8 4.0 0.061 13.3 4.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SnAC PF14619.6 KPI44544.1 - 0.075 13.6 0.2 0.075 13.6 0.2 3.9 5 0 0 5 5 3 0 Snf2-ATP coupling, chromatin remodelling complex zf-HC5HC2H_2 PF13832.6 KPI44544.1 - 0.22 11.7 5.0 0.14 12.3 2.4 2.0 2 0 0 2 2 1 0 PHD-zinc-finger like domain PHD_2 PF13831.6 KPI44544.1 - 0.62 9.7 10.4 0.05 13.2 3.5 2.7 2 1 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 KPI44544.1 - 0.69 10.2 6.3 0.25 11.6 2.8 2.1 2 0 0 2 2 1 0 PHD-like zinc-binding domain FAM176 PF14851.6 KPI44544.1 - 3.5 7.3 11.6 14 5.3 1.5 4.1 4 0 0 4 4 4 0 FAM176 family DUF866 PF05907.13 KPI44544.1 - 5.4 6.9 6.0 28 4.6 1.2 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) PG_binding_1 PF01471.18 KPI44545.1 - 0.00033 20.8 0.0 0.23 11.7 0.0 3.4 3 0 0 3 3 3 2 Putative peptidoglycan binding domain MBOAT PF03062.19 KPI44546.1 - 9.5e-34 117.3 17.5 4e-33 115.2 12.2 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family NAD_binding_10 PF13460.6 KPI44546.1 - 0.0002 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding PBP_N PF17093.5 KPI44546.1 - 0.0083 16.4 0.8 0.0083 16.4 0.8 3.0 2 0 0 2 2 2 1 Penicillin-binding protein N-terminus MFS_1 PF07690.16 KPI44548.1 - 6.5e-35 120.7 51.6 1.8e-28 99.5 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44548.1 - 5.3e-05 22.3 8.1 0.00013 21.0 7.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter UPF0449 PF15136.6 KPI44548.1 - 0.21 12.0 0.3 0.37 11.3 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Peripla_BP_2 PF01497.18 KPI44549.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF4140 PF13600.6 KPI44549.1 - 0.64 10.5 3.0 1.9 8.9 0.3 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SelK_SelG PF10961.8 KPI44549.1 - 5.5 7.7 10.0 6.3 7.5 9.2 1.6 1 1 1 2 2 2 0 Selenoprotein SelK_SelG TFR_dimer PF04253.15 KPI44550.1 - 1.2e-22 80.3 0.0 2.6e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KPI44550.1 - 7.4e-12 45.1 0.3 1.7e-11 44.0 0.3 1.6 1 0 0 1 1 1 1 PA domain Folliculin PF11704.8 KPI44552.1 - 1.1e-50 172.2 0.1 5.3e-50 169.9 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport ELO PF01151.18 KPI44553.1 - 3.5e-63 213.4 21.2 4.2e-63 213.2 21.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PCI PF01399.27 KPI44554.1 - 7.2e-19 68.2 0.3 7.2e-19 68.2 0.3 2.4 3 0 0 3 3 3 1 PCI domain DUF5425 PF17472.2 KPI44554.1 - 0.051 14.4 2.1 0.19 12.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5425) TPR_2 PF07719.17 KPI44554.1 - 0.3 11.3 3.1 5 7.5 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Cnd1_N PF12922.7 KPI44556.1 - 6.9e-56 188.7 0.1 1.8e-55 187.3 0.1 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KPI44556.1 - 4.8e-48 163.3 0.7 9.2e-41 139.6 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KPI44556.1 - 4.6e-10 39.8 0.8 0.0034 17.7 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KPI44556.1 - 1.3e-09 37.4 7.3 0.027 14.7 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 KPI44556.1 - 3e-05 22.8 0.7 0.088 11.3 0.0 2.6 2 0 0 2 2 2 2 Adaptin N terminal region Cnd3 PF12719.7 KPI44556.1 - 3.7e-05 23.1 2.6 0.011 15.0 0.5 3.4 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KPI44556.1 - 8e-05 23.0 3.9 0.55 10.8 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 KPI44556.1 - 0.00027 21.1 0.0 0.011 15.9 0.0 3.3 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 VAD1-2 PF15310.6 KPI44556.1 - 0.014 15.3 1.4 0.04 13.8 1.4 1.7 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Abhydrolase_1 PF00561.20 KPI44558.1 - 3.2e-06 27.0 0.0 0.00028 20.6 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44558.1 - 2.6e-05 25.0 0.0 3.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI44558.1 - 6.7e-05 22.3 0.0 0.11 11.7 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KPI44558.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 KPI44558.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KPI44558.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPI44558.1 - 0.052 13.1 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.14 KPI44558.1 - 0.12 11.6 0.0 4.5 6.5 0.0 2.4 2 1 1 3 3 3 0 Secretory lipase Lin-8 PF03353.15 KPI44559.1 - 0.32 10.5 2.1 0.47 10.0 2.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist COesterase PF00135.28 KPI44560.1 - 2e-62 211.7 0.0 9.9e-62 209.4 0.0 1.9 1 1 1 2 2 2 1 Carboxylesterase family FAD_binding_3 PF01494.19 KPI44560.1 - 2.6e-11 43.4 0.6 1.5e-05 24.4 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Abhydrolase_3 PF07859.13 KPI44560.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold NAD_binding_8 PF13450.6 KPI44560.1 - 0.00021 21.4 0.3 0.0007 19.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI44560.1 - 0.017 14.4 0.0 0.29 10.3 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PSCyt2 PF07583.11 KPI44560.1 - 0.038 13.9 0.1 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Chlorophyllase2 PF12740.7 KPI44560.1 - 0.049 12.5 0.0 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Pyr_redox PF00070.27 KPI44560.1 - 0.049 14.2 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase S_100 PF01023.19 KPI44560.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain RNA_polI_A34 PF08208.11 KPI44562.1 - 1.7e-18 67.5 2.2 1.7e-18 67.5 2.2 2.8 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Apt1 PF10351.9 KPI44562.1 - 0.26 10.1 9.6 0.36 9.6 9.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KPI44562.1 - 0.31 9.3 14.0 0.43 8.8 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KPI44562.1 - 1.6 7.4 8.2 2.2 7.0 8.2 1.2 1 0 0 1 1 1 0 Presenilin Pneumo_att_G PF05539.11 KPI44562.1 - 2.4 7.7 8.6 4.3 6.8 8.6 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Macoilin PF09726.9 KPI44562.1 - 3.4 6.1 8.5 4.3 5.8 8.5 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KPI44562.1 - 3.6 4.6 8.1 4.7 4.2 8.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Raftlin PF15250.6 KPI44562.1 - 4.1 6.1 7.9 6.2 5.5 7.9 1.2 1 0 0 1 1 1 0 Raftlin PI3K_1B_p101 PF10486.9 KPI44562.1 - 5.5 4.6 12.2 7.2 4.2 12.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Myotub-related PF06602.14 KPI44563.1 - 4.2e-145 483.1 0.0 5.3e-145 482.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KPI44563.1 - 0.1 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KPI44563.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TPR_19 PF14559.6 KPI44564.1 - 2.9e-06 27.7 1.6 0.015 15.8 0.6 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_21 PF09976.9 KPI44564.1 - 0.017 14.8 1.0 0.11 12.2 0.6 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF2462 PF09495.10 KPI44565.1 - 3.2e-21 75.8 8.9 3.2e-21 75.8 8.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Lgl_C PF08596.10 KPI44566.1 - 1.2e-114 383.0 0.0 2.2e-114 382.2 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KPI44566.1 - 1.8e-07 31.7 5.9 0.06 14.3 0.2 5.6 4 1 0 4 4 4 3 WD domain, G-beta repeat MRP-L20 PF12824.7 KPI44567.1 - 2.5e-45 154.6 4.4 3e-45 154.3 4.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KPI44567.1 - 0.041 13.9 0.2 0.057 13.4 0.2 1.2 1 0 0 1 1 1 0 Neugrin SMC_N PF02463.19 KPI44569.1 - 5.7e-65 218.8 12.2 1.2e-34 119.7 8.2 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KPI44569.1 - 4.7e-26 91.4 0.2 1.7e-25 89.6 0.0 2.2 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KPI44569.1 - 9.9e-14 51.8 0.1 1.1e-05 25.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KPI44569.1 - 0.00023 20.9 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FPP PF05911.11 KPI44569.1 - 0.0012 17.1 12.3 0.0012 17.1 12.3 3.5 3 0 0 3 3 3 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 KPI44569.1 - 0.004 17.3 6.3 0.004 17.3 6.3 7.6 3 2 4 7 7 5 1 Tropomyosin like GAS PF13851.6 KPI44569.1 - 0.0043 16.4 14.7 0.0043 16.4 14.7 6.8 2 2 4 6 6 6 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KPI44569.1 - 0.0048 16.9 7.9 0.0048 16.9 7.9 7.2 3 2 2 7 7 7 1 Laminin Domain II Vps23_core PF09454.10 KPI44569.1 - 0.0079 16.1 0.1 0.03 14.3 0.1 2.0 1 0 0 1 1 1 1 Vps23 core domain SbcCD_C PF13558.6 KPI44569.1 - 0.057 13.7 0.0 0.88 9.8 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Spc7 PF08317.11 KPI44569.1 - 4.6 6.0 108.7 1.7 7.4 16.5 6.0 2 2 4 6 6 6 0 Spc7 kinetochore protein DnaJ PF00226.31 KPI44571.1 - 1.2e-20 73.4 2.7 2.2e-20 72.5 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain Aldo_ket_red PF00248.21 KPI44572.1 - 3.2e-51 174.3 0.0 7.9e-49 166.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3301 PF11743.8 KPI44572.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) EpsG PF14897.6 KPI44573.1 - 0.017 14.5 8.8 0.012 15.0 7.1 1.5 1 1 0 1 1 1 0 EpsG family OrsD PF12013.8 KPI44574.1 - 0.57 10.6 4.0 4.9 7.6 0.7 2.4 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1644 PF07800.12 KPI44574.1 - 0.95 9.5 3.8 0.39 10.8 0.6 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1644) Cupin_7 PF12973.7 KPI44575.1 - 5.6e-07 29.4 0.2 8.5e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KPI44575.1 - 0.046 13.4 0.4 0.079 12.7 0.4 1.5 1 0 0 1 1 1 0 Cupin domain DUF1793 PF08760.11 KPI44576.1 - 1.1e-65 221.1 0.9 1.9e-65 220.3 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KPI44576.1 - 1e-60 204.4 0.6 2.3e-47 160.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KPI44576.1 - 4.4e-39 134.6 0.0 8.4e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KPI44576.1 - 0.00021 20.8 0.1 0.00045 19.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) HRXXH PF13933.6 KPI44577.1 - 0.13 11.8 1.1 0.73 9.3 0.6 2.0 2 0 0 2 2 2 0 Putative peptidase family DUF1604 PF07713.13 KPI44578.1 - 1.8e-32 111.0 1.6 1.8e-32 111.0 1.6 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KPI44578.1 - 1e-07 31.7 1.7 3.2e-07 30.1 1.7 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KPI44578.1 - 0.043 13.9 0.3 0.043 13.9 0.3 3.1 4 0 0 4 4 4 0 G-patch domain adh_short_C2 PF13561.6 KPI44579.1 - 1e-20 74.3 0.1 1.3e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44579.1 - 1.6e-15 57.1 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI44579.1 - 0.0022 17.9 0.1 0.0033 17.4 0.1 1.2 1 0 0 1 1 1 1 KR domain SARAF PF06682.12 KPI44580.1 - 1.2e-101 340.7 1.8 1.4e-101 340.5 1.8 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Rick_17kDa_Anti PF05433.15 KPI44580.1 - 0.1 12.5 3.0 0.23 11.4 3.0 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain NDUF_B12 PF08122.12 KPI44580.1 - 0.19 11.8 1.1 11 6.2 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family AA_permease_2 PF13520.6 KPI44581.1 - 2.5e-63 214.4 50.3 3.1e-63 214.1 50.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI44581.1 - 6.8e-14 51.3 39.6 1e-13 50.7 39.6 1.2 1 0 0 1 1 1 1 Amino acid permease GFO_IDH_MocA PF01408.22 KPI44581.1 - 3.7e-13 50.4 0.1 6.7e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.7 KPI44583.1 - 1.3e-17 65.2 0.0 1.5e-17 64.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI44583.1 - 0.024 13.9 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI44583.1 - 0.029 14.0 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 KPI44583.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 KPI44583.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AIG1 PF04548.16 KPI44584.1 - 0.025 13.9 0.1 0.45 9.8 0.0 2.8 3 0 0 3 3 3 0 AIG1 family SET PF00856.28 KPI44586.1 - 0.00045 20.6 0.0 0.0077 16.6 0.0 2.3 1 1 0 1 1 1 1 SET domain HSF_DNA-bind PF00447.17 KPI44587.1 - 4.4e-32 110.6 1.7 4.4e-32 110.6 1.7 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 KPI44587.1 - 3.8e-23 81.8 0.2 1.1e-22 80.3 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 KPI44587.1 - 0.038 14.5 0.1 0.1 13.1 0.1 1.7 1 0 0 1 1 1 0 Ets-domain NRBF2 PF08961.10 KPI44587.1 - 0.039 13.6 0.9 0.072 12.7 0.9 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 KPI44587.1 - 0.41 11.3 3.4 0.98 10.1 3.4 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Abhydrolase_6 PF12697.7 KPI44588.1 - 3.9e-15 57.1 0.2 6.7e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI44588.1 - 6e-11 42.5 0.1 8.6e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI44588.1 - 9.4e-10 38.1 0.4 1.8e-09 37.2 0.3 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 OSK PF17182.4 KPI44588.1 - 0.018 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 OSK domain BIR PF00653.21 KPI44589.1 - 4.1e-45 152.3 4.5 1.6e-22 80.0 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain NAD_binding_2 PF03446.15 KPI44590.1 - 7.5e-28 97.7 0.1 1.9e-27 96.4 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KPI44590.1 - 7e-19 68.3 0.4 1.4e-16 60.9 0.1 2.8 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KPI44590.1 - 6.4e-07 29.9 0.4 2.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KPI44590.1 - 0.0069 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KPI44590.1 - 0.0086 15.7 0.0 0.026 14.1 0.0 1.9 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KPI44590.1 - 0.023 14.6 0.1 0.073 13.0 0.1 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KPI44590.1 - 0.026 14.1 1.2 2.4 7.7 1.2 2.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KPI44590.1 - 0.06 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_C PF03720.15 KPI44590.1 - 0.097 13.1 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TEX13 PF15186.6 KPI44591.1 - 0.12 12.1 1.5 0.2 11.3 1.5 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF4407 PF14362.6 KPI44591.1 - 0.19 11.1 0.3 0.27 10.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GST_N PF02798.20 KPI44592.1 - 7.5e-08 32.6 0.2 2.3e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KPI44592.1 - 1e-07 32.3 0.1 1.6e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI44592.1 - 8.4e-05 22.8 0.1 0.00014 22.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI44592.1 - 0.00094 19.2 0.2 0.002 18.1 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP-synt_J PF04911.12 KPI44593.1 - 4.6e-12 45.3 0.1 6.7e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase j chain GST_N_3 PF13417.6 KPI44594.1 - 3.3e-08 33.8 0.1 5.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI44594.1 - 3.9e-08 33.2 0.5 7.3e-08 32.3 0.5 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI44594.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KPI44594.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KPI44594.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Terminase_5 PF06056.12 KPI44594.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DnaJ PF00226.31 KPI44595.1 - 5e-20 71.4 0.8 1.2e-19 70.1 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 KPI44596.1 - 1.7e-07 32.0 3.9 2.8e-07 31.2 3.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NDT80_PhoG PF05224.12 KPI44598.1 - 0.028 14.6 0.6 0.072 13.3 0.2 1.8 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family TFIIA PF03153.13 KPI44598.1 - 0.5 10.3 16.4 0.72 9.8 16.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GP67 PF17634.2 KPI44600.1 - 0.013 15.9 14.5 0.024 15.0 14.5 1.4 1 0 0 1 1 1 0 Gene product 67 DUF3022 PF11226.8 KPI44600.1 - 0.064 13.7 0.1 0.092 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) TFIIA PF03153.13 KPI44600.1 - 0.12 12.3 9.5 0.15 12.0 9.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KPI44600.1 - 0.13 11.9 12.1 0.2 11.4 12.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KPI44600.1 - 0.56 10.6 16.7 1.1 9.7 16.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 KPI44600.1 - 0.66 9.5 8.2 0.74 9.4 8.2 1.2 1 0 0 1 1 1 0 PPP4R2 GCIP PF13324.6 KPI44600.1 - 1.3 8.5 6.5 2 7.9 6.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Astro_capsid_p PF12226.8 KPI44600.1 - 2.4 7.2 7.2 2.4 7.2 7.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRM_1 PF00076.22 KPI44601.1 - 2.7e-12 46.3 0.0 6.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI44601.1 - 0.033 14.3 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif HTH_57 PF18679.1 KPI44602.1 - 0.067 13.5 0.8 0.75 10.1 0.0 2.7 3 0 0 3 3 3 0 ThcOx helix turn helix domain Fungal_trans_2 PF11951.8 KPI44603.1 - 9.1e-08 31.3 0.0 1.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YihI PF04220.12 KPI44603.1 - 0.16 11.7 2.7 0.24 11.1 2.7 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Peptidase_C12 PF01088.21 KPI44606.1 - 3.5e-49 167.4 0.0 4.6e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MttA_Hcf106 PF02416.16 KPI44606.1 - 0.17 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 mttA/Hcf106 family TAF8_C PF10406.9 KPI44607.1 - 2.1e-17 63.4 1.5 5.6e-17 62.0 1.5 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term 2-Hacid_dh_C PF02826.19 KPI44608.1 - 1.3e-53 180.9 0.0 1.9e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI44608.1 - 9.1e-26 90.1 0.0 1e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI44608.1 - 2.9e-05 24.3 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KPI44608.1 - 0.035 14.7 0.1 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KPI44608.1 - 0.038 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans_2 PF11951.8 KPI44609.1 - 0.00026 19.9 3.1 0.00042 19.2 3.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4913 PF16259.5 KPI44609.1 - 0.27 11.3 1.0 6.3 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4913) MFS_1 PF07690.16 KPI44610.1 - 1.1e-35 123.2 29.0 1.1e-35 123.2 29.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44610.1 - 1.9e-11 43.5 1.9 1.9e-11 43.5 1.9 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KPI44610.1 - 8.3e-05 21.2 1.6 0.00013 20.5 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FixP_N PF14715.6 KPI44610.1 - 5.6 6.8 7.7 0.36 10.6 0.9 2.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP TAXi_N PF14543.6 KPI44611.1 - 0.017 15.3 1.7 0.73 10.0 0.0 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Maf PF02545.14 KPI44612.1 - 9.5e-51 171.9 0.0 1.1e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ILVD_EDD PF00920.21 KPI44614.1 - 1.6e-203 677.1 0.2 1.8e-203 676.9 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family p450 PF00067.22 KPI44615.1 - 3.8e-53 180.9 0.0 2.4e-41 142.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AMMECR1 PF01871.17 KPI44615.1 - 0.21 11.2 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 AMMECR1 Glycos_transf_2 PF00535.26 KPI44616.1 - 2.9e-30 105.3 0.0 3.9e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KPI44616.1 - 2.1e-15 57.2 0.0 2.8e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 KPI44616.1 - 7.5e-05 22.4 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KPI44616.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KPI44616.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 NAD_binding_1 PF00175.21 KPI44617.1 - 9.1e-33 113.2 0.0 1.7e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPI44617.1 - 2.2e-23 82.5 0.0 4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KPI44617.1 - 8.3e-09 35.8 0.0 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KPI44617.1 - 0.006 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain zf-C2H2 PF00096.26 KPI44618.1 - 0.0016 18.8 0.4 0.0035 17.7 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI44618.1 - 0.14 13.0 0.3 0.33 11.9 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger GFA PF04828.14 KPI44619.1 - 3.7e-10 40.0 0.0 4.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NTP_transf_2 PF01909.23 KPI44620.1 - 0.0025 18.1 0.0 0.0051 17.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KPI44620.1 - 0.004 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF2373 PF10180.9 KPI44621.1 - 6.2e-19 67.6 0.9 1.1e-18 66.8 0.9 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) zf-Tim10_DDP PF02953.15 KPI44622.1 - 5.3e-21 74.0 1.5 6.3e-21 73.8 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AA_permease_2 PF13520.6 KPI44623.1 - 4.8e-51 173.9 56.2 6e-51 173.6 56.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI44623.1 - 4.8e-26 91.4 47.3 6.4e-26 91.0 47.3 1.1 1 0 0 1 1 1 1 Amino acid permease ThrE PF06738.12 KPI44624.1 - 4.9e-64 216.0 18.9 1.5e-59 201.3 2.3 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KPI44624.1 - 2.3e-12 47.2 30.9 1.1e-11 45.0 15.7 2.7 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE GDE_N PF12439.8 KPI44624.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Zn_clus PF00172.18 KPI44625.1 - 1.2e-09 38.1 8.1 1.9e-09 37.5 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.11 KPI44625.1 - 0.061 13.3 3.4 0.1 12.5 3.4 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain adh_short PF00106.25 KPI44627.1 - 4e-37 127.6 0.0 5.5e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI44627.1 - 6.6e-30 104.4 0.0 8.8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 KPI44627.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KPI44627.1 - 0.13 12.2 0.2 0.53 10.2 0.1 2.0 2 1 0 2 2 2 0 KR domain Epimerase PF01370.21 KPI44627.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_N_3 PF13417.6 KPI44628.1 - 9.5e-14 51.6 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KPI44628.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI44628.1 - 1.5e-09 38.0 0.1 4.8e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI44628.1 - 2.3e-08 34.1 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI44628.1 - 3.5e-08 33.6 0.0 5.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI44628.1 - 0.023 14.7 0.2 0.037 14.1 0.2 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tubulin PF00091.25 KPI44629.1 - 4.9e-68 229.2 0.0 7.3e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KPI44629.1 - 3.3e-22 79.0 0.6 2e-16 60.3 0.2 2.4 1 1 1 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KPI44629.1 - 3.2e-05 24.2 0.0 7.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KPI44629.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KPI44629.1 - 0.0032 16.7 0.1 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Coa1 PF08695.10 KPI44630.1 - 4.3e-39 132.9 0.0 5.9e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CRAL_TRIO PF00650.20 KPI44631.1 - 1.9e-38 131.7 0.0 3.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KPI44631.1 - 7e-07 29.3 0.1 1.5e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KPI44631.1 - 0.0018 18.4 0.0 0.0053 16.9 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Tropomyosin_1 PF12718.7 KPI44632.1 - 0.00021 21.4 13.0 0.00046 20.4 13.0 1.5 1 0 0 1 1 1 1 Tropomyosin like TSC22 PF01166.18 KPI44632.1 - 0.00029 21.1 3.5 0.01 16.1 0.0 3.4 3 0 0 3 3 3 1 TSC-22/dip/bun family Macoilin PF09726.9 KPI44632.1 - 0.0049 15.5 4.5 0.0069 15.0 4.5 1.2 1 0 0 1 1 1 1 Macoilin family HALZ PF02183.18 KPI44632.1 - 0.0086 16.3 0.7 1.4 9.2 0.0 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF4686 PF15742.5 KPI44632.1 - 0.0092 15.2 13.1 0.014 14.6 13.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) GAS PF13851.6 KPI44632.1 - 0.0095 15.3 12.5 0.043 13.2 11.9 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KPI44632.1 - 0.036 15.0 10.0 0.091 13.7 10.0 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Phage_Nu1 PF07471.12 KPI44632.1 - 0.066 13.0 2.6 0.14 11.9 2.6 1.5 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Fungal_TACC PF12709.7 KPI44632.1 - 0.34 11.4 5.5 2.5 8.6 1.7 2.8 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins V_ATPase_I PF01496.19 KPI44632.1 - 0.34 8.8 12.7 0.043 11.7 1.4 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 KPI44632.1 - 0.43 10.7 11.1 2.8 8.1 0.9 3.7 3 0 0 3 3 3 0 Basic region leucine zipper YabA PF06156.13 KPI44632.1 - 0.46 11.2 7.6 3.9 8.2 0.2 2.6 1 1 1 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 KPI44632.1 - 0.72 10.2 6.6 1.3 9.3 6.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SIKE PF05769.11 KPI44632.1 - 1.2 9.1 10.4 2.1 8.2 10.4 1.3 1 0 0 1 1 1 0 SIKE family DUF5082 PF16888.5 KPI44632.1 - 1.6 9.1 10.2 1.3 9.3 7.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 KPI44632.1 - 1.8 8.3 3.3 3.8 7.3 3.3 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Exonuc_VII_L PF02601.15 KPI44632.1 - 2.3 7.7 7.1 3.6 7.1 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CHASE3 PF05227.13 KPI44632.1 - 2.6 7.9 10.8 5.4 6.9 10.8 1.5 1 0 0 1 1 1 0 CHASE3 domain ZapB PF06005.12 KPI44632.1 - 3.4 8.2 17.1 3.1 8.3 0.0 3.4 2 1 1 3 3 3 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 KPI44632.1 - 3.8 7.8 13.1 1.8 8.8 0.3 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KPI44632.1 - 6.9 7.1 15.7 6.9 7.1 5.3 2.1 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 KPI44632.1 - 8.6 5.6 10.9 21 4.3 10.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TauD PF02668.16 KPI44633.1 - 6.5e-56 190.1 1.9 8.6e-56 189.7 1.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family VTC PF09359.10 KPI44634.1 - 1e-06 28.4 0.3 9.3e-06 25.2 0.3 2.4 1 1 0 1 1 1 1 VTC domain SPX PF03105.19 KPI44634.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 5.4 3 2 1 4 4 4 3 SPX domain TSNAXIP1_N PF15739.5 KPI44634.1 - 0.1 13.0 0.1 0.42 11.0 0.1 2.1 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Amidase PF01425.21 KPI44635.1 - 7.2e-94 315.3 0.0 8.8e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Cupin_2 PF07883.11 KPI44637.1 - 1.4e-10 40.7 0.3 2.3e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KPI44637.1 - 4.6e-06 26.5 0.2 8.2e-06 25.7 0.2 1.4 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.19 KPI44637.1 - 9.6e-05 22.3 0.1 0.00013 21.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KPI44637.1 - 0.00094 18.8 0.1 0.0066 16.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KPI44637.1 - 0.012 15.3 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Cupin ARD PF03079.14 KPI44637.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Rogdi_lz PF10259.9 KPI44639.1 - 3e-77 259.7 0.0 3.4e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein UAA PF08449.11 KPI44640.1 - 4.1e-39 134.6 13.0 5.5e-39 134.2 13.0 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KPI44640.1 - 2.7e-05 23.5 3.6 0.003 16.8 1.0 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KPI44640.1 - 0.00022 21.4 25.8 0.00049 20.3 11.5 2.7 2 1 0 2 2 2 2 EamA-like transporter family GTP_EFTU PF00009.27 KPI44642.1 - 1.1e-33 116.4 4.8 4e-32 111.3 4.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KPI44642.1 - 2.2e-13 50.2 6.6 2.7e-12 46.7 3.3 3.5 2 1 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KPI44642.1 - 7.5e-09 35.7 0.2 2.1e-08 34.2 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KPI44642.1 - 2.2e-05 24.0 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KPI44642.1 - 5.2e-05 23.6 2.5 0.086 13.2 0.1 3.1 2 1 0 2 2 2 2 Elongation factor Tu domain 2 Dynamin_N PF00350.23 KPI44642.1 - 0.00078 19.5 3.4 0.47 10.5 0.2 3.3 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KPI44642.1 - 0.0012 18.7 4.2 0.0061 16.5 0.1 2.7 2 1 1 3 3 3 1 RsgA GTPase IF2_N PF04760.15 KPI44642.1 - 0.0017 18.1 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 KPI44642.1 - 0.0067 16.0 1.0 0.02 14.4 1.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KPI44642.1 - 0.026 13.9 0.3 0.16 11.4 0.3 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KPI44642.1 - 0.032 14.0 0.4 0.13 12.0 0.4 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KPI44642.1 - 0.073 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Ras family Amidohydro_2 PF04909.14 KPI44643.1 - 4.9e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KPI44643.1 - 0.00048 19.5 0.0 0.0044 16.4 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 KPI44643.1 - 0.16 12.5 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain Aldedh PF00171.22 KPI44644.1 - 5.4e-92 308.7 0.0 1.1e-89 301.2 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KPI44645.1 - 6.9e-60 202.3 0.0 1e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KPI44645.1 - 0.0017 18.7 16.7 0.2 12.2 3.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI44645.1 - 0.46 11.5 13.8 2.6 9.1 2.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Tma16 PF11176.8 KPI44647.1 - 1.5e-45 154.6 0.7 1.8e-45 154.4 0.7 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Alb1 PF09135.11 KPI44647.1 - 0.081 13.8 2.8 0.61 11.0 0.5 2.1 2 0 0 2 2 2 0 Alb1 DUF4147 PF13660.6 KPI44647.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) PNK3P PF08645.11 KPI44649.1 - 2.2e-51 173.8 0.0 3.3e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KPI44649.1 - 1.4e-23 83.6 0.0 8e-11 42.3 0.0 2.6 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KPI44649.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KPI44649.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KPI44649.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KPI44649.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KPI44649.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Vps35 PF03635.17 KPI44650.1 - 0 1017.6 0.8 0 1017.4 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pex14_N PF04695.13 KPI44650.1 - 0.7 10.5 4.9 0.61 10.7 1.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAF-AH_p_II PF03403.13 KPI44651.1 - 7.4e-08 31.3 0.2 2.6e-06 26.2 0.3 2.3 2 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KPI44651.1 - 8.6e-07 28.1 0.0 2e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KPI44651.1 - 0.0013 17.8 0.4 0.0024 16.9 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S15 PF02129.18 KPI44651.1 - 0.032 13.8 0.4 0.064 12.8 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Amidohydro_1 PF01979.20 KPI44652.1 - 1.3e-63 215.4 1.2 9.4e-63 212.6 1.2 2.0 1 1 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KPI44652.1 - 8.2e-55 184.3 1.4 1.2e-54 183.8 0.6 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KPI44652.1 - 3.8e-41 139.1 0.1 1.5e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KPI44652.1 - 6.8e-35 119.4 0.1 1.5e-34 118.3 0.1 1.5 1 0 0 1 1 1 1 Urease, gamma subunit HMG_box PF00505.19 KPI44652.1 - 5.9e-10 39.4 2.2 1.2e-09 38.5 2.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Amidohydro_3 PF07969.11 KPI44652.1 - 7.4e-08 32.3 0.2 2e-05 24.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family HMG_box_2 PF09011.10 KPI44652.1 - 0.00022 21.8 2.5 0.00042 20.8 2.5 1.5 1 0 0 1 1 1 1 HMG-box domain Gti1_Pac2 PF09729.9 KPI44653.1 - 2.2e-61 207.1 0.1 1.2e-60 204.7 0.0 2.2 2 1 0 2 2 2 1 Gti1/Pac2 family Ank_2 PF12796.7 KPI44654.1 - 4.3e-36 123.4 3.7 4.4e-10 40.0 0.1 4.0 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KPI44654.1 - 4e-27 94.2 9.0 4.4e-09 36.7 0.0 6.7 4 3 3 7 7 7 5 Ankyrin repeats (many copies) SPX PF03105.19 KPI44654.1 - 1.2e-20 74.9 12.3 6.2e-09 36.3 0.4 3.3 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 KPI44654.1 - 1e-17 62.4 2.9 0.001 19.4 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KPI44654.1 - 4.1e-17 62.0 1.8 4.1e-06 27.0 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KPI44654.1 - 7.8e-12 45.1 3.7 0.041 14.4 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat GDPD PF03009.17 KPI44654.1 - 6.1e-11 42.5 0.0 1.8e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CCDC154 PF15450.6 KPI44654.1 - 0.015 13.8 0.7 0.096 11.2 0.7 2.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 154 P68HR PF08061.11 KPI44655.1 - 0.12 12.5 1.0 0.27 11.4 1.0 1.5 1 0 0 1 1 1 0 P68HR (NUC004) repeat TatC PF00902.18 KPI44655.1 - 3.8 7.3 12.9 88 2.8 12.9 2.3 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) PBP1_TM PF14812.6 KPI44656.1 - 0.71 10.3 6.5 2.2 8.7 4.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PALP PF00291.25 KPI44657.1 - 3.7e-57 194.0 0.2 5.2e-57 193.5 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.6 KPI44657.1 - 5.6e-39 134.0 1.5 6.5e-39 133.8 0.3 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KPI44657.1 - 4.1e-15 55.3 0.0 7.9e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Isocitrate lyase family 3HCDH_N PF02737.18 KPI44657.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KPI44658.1 - 2.3e-15 56.9 0.2 3e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44658.1 - 7.5e-13 49.6 3.9 1e-12 49.2 3.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KPI44658.1 - 0.0062 16.1 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KPI44658.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 KPI44659.1 - 1.1e-44 153.0 0.0 1.3e-30 106.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.18 KPI44660.1 - 3.9e-23 81.8 0.5 8.5e-23 80.7 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain SHMT PF00464.19 KPI44663.1 - 4.9e-207 687.3 0.0 5.7e-207 687.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KPI44663.1 - 4.7e-06 26.0 0.0 1.5e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI44663.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KPI44663.1 - 0.027 13.8 0.0 0.048 12.9 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KPI44663.1 - 0.14 10.7 0.0 0.25 9.8 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CoA_binding PF02629.19 KPI44664.1 - 6.7e-27 94.0 3.0 2.7e-26 92.1 0.5 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KPI44664.1 - 2.1e-21 76.3 0.2 3.7e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KPI44664.1 - 1.2e-07 31.6 0.1 2e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KPI44664.1 - 0.0016 18.9 0.0 0.0035 17.8 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain UPF0016 PF01169.19 KPI44665.1 - 2.2e-41 140.0 23.0 5e-21 74.8 7.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DEAD PF00270.29 KPI44667.1 - 1.2e-42 145.6 0.0 3.2e-42 144.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI44667.1 - 4.3e-19 68.9 0.0 6.6e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 KPI44667.1 - 0.03 13.6 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain ResIII PF04851.15 KPI44667.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ion_trans_2 PF07885.16 KPI44668.1 - 5.9e-23 80.6 26.7 5.5e-16 58.3 10.1 2.8 3 0 0 3 3 3 2 Ion channel zf-CCCH PF00642.24 KPI44669.1 - 6.4e-05 22.8 1.8 6.4e-05 22.8 1.8 2.6 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPI44669.1 - 3.4 7.9 13.9 0.13 12.4 6.3 2.7 3 0 0 3 3 3 0 Zinc finger domain NIF3 PF01784.18 KPI44670.1 - 7.4e-55 186.2 0.0 9.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Transp_cyt_pur PF02133.15 KPI44671.1 - 1.9e-18 66.5 32.2 1.8e-14 53.4 30.8 2.5 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin TMEM239 PF15841.5 KPI44671.1 - 0.0025 17.7 0.8 0.0068 16.3 0.8 1.7 1 0 0 1 1 1 1 Transmembrane protein 239 family PHD PF00628.29 KPI44672.1 - 2.4e-10 40.1 6.8 2.4e-10 40.1 6.8 2.6 3 0 0 3 3 3 1 PHD-finger ARS2 PF04959.13 KPI44672.1 - 0.017 15.5 1.1 0.017 15.5 1.1 2.3 2 1 0 2 2 2 0 Arsenite-resistance protein 2 zf-CpG_bind_C PF12269.8 KPI44672.1 - 0.11 12.3 3.3 2.4 7.9 0.0 3.1 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain Pkinase PF00069.25 KPI44673.1 - 1.7e-23 83.4 0.0 2.4e-22 79.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44673.1 - 4.7e-07 29.4 1.1 0.00076 18.8 0.1 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase adh_short_C2 PF13561.6 KPI44674.1 - 4.6e-36 124.6 0.5 5.6e-36 124.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44674.1 - 1.2e-16 60.8 0.1 1.5e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Osmo_MPGsynth PF09488.10 KPI44675.1 - 0.0086 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DUF3425 PF11905.8 KPI44677.1 - 5.9e-11 42.4 1.4 2.2e-10 40.6 1.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KPI44677.1 - 0.021 14.9 6.3 0.021 14.9 6.3 2.8 2 1 1 3 3 3 0 bZIP transcription factor DUF3669 PF12417.8 KPI44678.1 - 2.7e-16 59.5 1.1 6.8e-16 58.2 0.2 2.2 2 0 0 2 2 2 1 Zinc finger protein AA_permease_2 PF13520.6 KPI44680.1 - 7.6e-43 146.9 51.7 7.3e-33 114.0 28.9 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPI44680.1 - 6e-18 64.7 47.0 6.3e-16 58.0 28.4 2.0 1 1 1 2 2 2 2 Amino acid permease Pkinase PF00069.25 KPI44681.1 - 3.5e-64 216.7 0.0 4.2e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44681.1 - 2.5e-35 122.0 0.0 3.3e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI44681.1 - 6.9e-07 28.9 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KPI44681.1 - 0.00023 20.1 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KPI44681.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Fungal_trans PF04082.18 KPI44682.1 - 8.9e-12 44.6 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KPI44682.1 - 0.015 14.1 0.2 0.026 13.4 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2561 PF10812.8 KPI44682.1 - 0.091 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) CBP_BcsO PF17037.5 KPI44682.1 - 1.3 9.1 6.2 0.34 11.0 2.9 1.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO DUF647 PF04884.14 KPI44684.1 - 1.2e-35 123.3 1.9 1.7e-35 122.8 1.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Sulfotransfer_4 PF17784.1 KPI44685.1 - 4.6e-66 222.7 0.0 5.4e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI44685.1 - 0.0052 17.2 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Pkinase PF00069.25 KPI44686.1 - 3.8e-45 154.3 0.1 3.7e-25 88.8 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44686.1 - 5.6e-15 55.3 0.0 2.5e-11 43.4 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KPI44686.1 - 0.0083 16.1 0.9 0.059 13.3 0.7 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PP1c_bdg PF10488.9 KPI44686.1 - 0.29 10.6 8.7 0.034 13.6 2.5 2.3 3 0 0 3 3 3 0 Phosphatase-1 catalytic subunit binding region Ribosomal_S2 PF00318.20 KPI44687.1 - 3.4e-64 216.0 0.0 1.5e-63 213.9 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 Glyco_hydro_72 PF03198.14 KPI44688.1 - 1.4e-134 448.3 8.8 1.7e-134 448.0 8.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KPI44688.1 - 2e-13 50.8 0.9 6.6e-13 49.1 0.9 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_114 PF03537.13 KPI44688.1 - 0.0025 17.2 1.1 0.4 9.9 0.4 2.4 2 0 0 2 2 2 2 Glycoside-hydrolase family GH114 Pyr_redox_2 PF07992.14 KPI44689.1 - 1.3e-27 96.9 0.0 1.9e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KPI44689.1 - 3.4e-12 46.8 0.0 3.5e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI44689.1 - 2.5e-05 23.7 0.0 0.00075 18.8 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI44689.1 - 0.0013 17.9 0.4 0.076 12.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KPI44689.1 - 0.0016 18.4 2.5 10 6.1 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KPI44689.1 - 0.0021 17.7 6.1 0.6 9.6 0.1 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPI44689.1 - 0.05 12.4 1.8 2.1 7.1 0.2 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KPI44689.1 - 0.23 10.7 1.1 11 5.2 0.1 2.9 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 KPI44689.1 - 0.23 10.8 3.2 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.22 KPI44690.1 - 4.8e-21 75.0 0.0 1.1e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RF-1 PF00472.20 KPI44691.1 - 1.9e-18 66.5 2.4 3e-18 65.9 2.4 1.2 1 0 0 1 1 1 1 RF-1 domain Peptidase_C65 PF10275.9 KPI44692.1 - 0.045 13.2 0.1 0.61 9.5 0.1 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain MFS_1 PF07690.16 KPI44693.1 - 6.1e-17 61.6 23.9 9.2e-17 61.0 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 KPI44694.1 - 7e-17 60.9 0.2 1.5e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 Cupin domain LRR19-TM PF15176.6 KPI44694.1 - 0.00019 21.4 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain AraC_binding PF02311.19 KPI44694.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KPI44694.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Cupin RIFIN PF02009.16 KPI44694.1 - 0.0021 18.0 0.3 0.0029 17.5 0.3 1.2 1 0 0 1 1 1 1 Rifin Protocadherin PF08374.11 KPI44694.1 - 0.0029 17.6 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EutQ PF06249.12 KPI44694.1 - 0.0047 16.7 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ EphA2_TM PF14575.6 KPI44694.1 - 0.016 16.1 0.0 0.025 15.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KPI44694.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family LAX PF15681.5 KPI44694.1 - 0.053 12.3 0.1 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X CENP-C_C PF11699.8 KPI44694.1 - 0.071 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Orf78 PF06024.12 KPI44694.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Herpes_gE PF02480.16 KPI44694.1 - 0.084 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Cupin_3 PF05899.12 KPI44694.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DASH_Spc34 PF08657.10 KPI44696.1 - 2e-37 129.4 2.1 1e-22 81.2 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF3584 PF12128.8 KPI44696.1 - 0.021 12.4 2.6 0.027 12.0 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Spc19 PF08287.11 KPI44696.1 - 0.09 12.7 1.6 0.14 12.0 1.6 1.3 1 0 0 1 1 1 0 Spc19 DivIC PF04977.15 KPI44696.1 - 0.17 11.7 3.4 0.49 10.2 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Sipho_Gp157 PF05565.11 KPI44696.1 - 0.32 11.0 3.1 0.17 11.9 0.6 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 ZapB PF06005.12 KPI44696.1 - 5.1 7.6 8.8 1.3e+02 3.1 8.9 2.3 1 1 0 1 1 1 0 Cell division protein ZapB COesterase PF00135.28 KPI44697.1 - 2.8e-50 171.6 0.0 6.1e-50 170.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI44697.1 - 5.8e-07 29.6 0.4 4.1e-06 26.8 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold SHOCT PF09851.9 KPI44697.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Short C-terminal domain CENP-O PF09496.10 KPI44699.1 - 2.2e-45 155.2 0.1 1.9e-44 152.2 0.0 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component FPP PF05911.11 KPI44699.1 - 0.041 12.1 0.2 0.056 11.6 0.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 KPI44699.1 - 4.2 7.2 6.5 1.2 8.9 2.5 2.2 2 1 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 KPI44699.1 - 5.8 6.2 8.1 0.63 9.3 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3328 PF11807.8 KPI44700.1 - 1.7e-53 181.6 0.0 2.1e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2732 PF10809.8 KPI44701.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) UNC-50 PF05216.13 KPI44702.1 - 9.7e-79 264.0 12.0 1.3e-78 263.6 12.0 1.1 1 0 0 1 1 1 1 UNC-50 family Glyco_hydro_44 PF12891.7 KPI44702.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 DUF3959 PF13105.6 KPI44703.1 - 0.042 13.3 0.8 0.068 12.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) MciZ PF13072.6 KPI44703.1 - 0.11 12.3 0.6 0.26 11.1 0.6 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Peptidase_A8 PF01252.18 KPI44703.1 - 0.24 11.6 1.6 0.39 11.0 1.6 1.3 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF2721 PF11026.8 KPI44703.1 - 2.9 7.8 6.2 2.4 8.0 2.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) AMP-binding PF00501.28 KPI44704.1 - 3.9e-54 183.9 0.0 5.2e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mo25 PF08569.11 KPI44705.1 - 2.1e-88 296.9 1.1 2.4e-88 296.7 1.1 1.0 1 0 0 1 1 1 1 Mo25-like ICL PF00463.21 KPI44706.1 - 2.4e-278 923.9 2.6 6.3e-278 922.5 2.6 1.6 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KPI44706.1 - 2.3e-11 43.6 0.1 1.3e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Ribosomal_S10 PF00338.22 KPI44707.1 - 1.7e-26 92.3 0.4 2e-26 92.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF3328 PF11807.8 KPI44709.1 - 7.2e-20 71.7 0.0 1.3e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_43 PF04616.14 KPI44709.1 - 1.1e-18 67.6 1.8 7.9e-14 51.6 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Sacchrp_dh_NADP PF03435.18 KPI44710.1 - 2.1e-10 40.9 0.0 3.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Mis14 PF08641.12 KPI44711.1 - 1.6e-13 51.1 1.8 1.9e-13 50.9 0.6 1.8 2 1 0 2 2 2 1 Kinetochore protein Mis14 like Thiolase_N PF00108.23 KPI44712.1 - 1.2e-60 205.0 1.3 2.5e-60 204.0 1.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI44712.1 - 3e-45 152.8 0.5 6.9e-45 151.7 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KPI44712.1 - 0.00073 19.7 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KPI44712.1 - 1 8.9 8.4 0.068 12.7 1.3 2.4 3 1 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_92 PF07971.12 KPI44713.1 - 9.3e-139 463.3 2.9 1.2e-138 463.0 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KPI44713.1 - 7.3e-59 199.5 1.6 7.6e-59 199.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Nsp1_C PF05064.13 KPI44716.1 - 1.3e-32 112.0 2.3 1.3e-32 112.0 2.3 2.0 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KPI44716.1 - 1.4e-05 25.9 95.8 3.5e-05 24.5 17.9 7.0 1 1 5 6 6 4 3 Nucleoporin FG repeat region LTXXQ PF07813.12 KPI44716.1 - 0.051 14.3 0.4 0.16 12.7 0.4 1.8 1 0 0 1 1 1 0 LTXXQ motif family protein ParB PF08775.10 KPI44716.1 - 0.059 13.9 0.8 0.059 13.9 0.8 1.7 2 0 0 2 2 2 0 ParB family PI_PP_I PF18363.1 KPI44716.1 - 0.22 11.7 2.5 0.17 12.1 0.7 1.6 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Baculo_PEP_C PF04513.12 KPI44716.1 - 0.51 10.4 3.7 1.2 9.2 0.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KPI44716.1 - 0.73 10.3 8.1 4.2 7.9 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KPI44716.1 - 0.81 9.7 7.9 0.36 10.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 KPI44716.1 - 1.3 7.8 2.5 0.81 8.5 0.1 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein NPV_P10 PF05531.12 KPI44716.1 - 1.5 9.3 3.9 41 4.7 0.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KPI44716.1 - 1.7 9.0 4.8 0.76 10.2 0.5 2.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MscS_porin PF12795.7 KPI44716.1 - 1.9 8.0 8.1 1.9 8.0 1.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 KPI44716.1 - 5.3 6.3 9.4 2.1 7.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KPI44716.1 - 5.6 5.5 8.1 20 3.7 3.7 1.8 1 1 0 1 1 1 0 AAA domain Zwilch PF09817.9 KPI44717.1 - 0.055 11.9 0.8 0.079 11.4 0.8 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch AAA PF00004.29 KPI44719.1 - 3.9e-16 59.7 0.0 7.7e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI44719.1 - 1.7e-05 25.2 0.1 0.00011 22.7 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI44719.1 - 2.3e-05 24.7 0.2 0.00044 20.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KPI44719.1 - 0.004 17.2 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KPI44719.1 - 0.018 15.2 0.0 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KPI44719.1 - 0.039 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KPI44719.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KPI44719.1 - 0.071 12.8 0.1 0.2 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KPI44719.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KPI44719.1 - 0.11 13.1 0.0 0.36 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KPI44719.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CPT PF07931.12 KPI44719.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Aminotran_1_2 PF00155.21 KPI44720.1 - 2e-60 204.9 0.0 2.4e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5401 PF17380.2 KPI44720.1 - 0.063 11.4 0.0 0.063 11.4 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Cys_Met_Meta_PP PF01053.20 KPI44720.1 - 0.14 10.7 0.2 0.33 9.4 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme RskA PF10099.9 KPI44721.1 - 0.002 18.4 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA NAD_binding_10 PF13460.6 KPI44722.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KPI44722.1 - 7.8e-05 22.3 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KPI44722.1 - 0.0029 17.1 0.0 0.33 10.4 0.0 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KPI44722.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI44722.1 - 0.13 11.7 0.0 0.96 8.9 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase DUF3632 PF12311.8 KPI44723.1 - 5.3e-17 62.8 0.1 7.9e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) VASt PF16016.5 KPI44724.1 - 1.9e-33 116.1 0.0 3.4e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KPI44724.1 - 7.3e-15 55.3 0.4 4.2e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KPI44724.1 - 1.2e-09 38.6 0.2 8.8e-09 35.8 0.2 2.4 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 KPI44724.1 - 0.0035 17.7 0.1 0.0086 16.4 0.1 1.6 1 0 0 1 1 1 1 Plant pleckstrin homology-like region GRAM PF02893.20 KPI44724.1 - 0.0046 16.8 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 KPI44724.1 - 0.016 14.9 1.3 0.021 14.4 0.0 1.8 2 0 0 2 2 2 0 BAR domain PH_13 PF16652.5 KPI44724.1 - 0.14 12.0 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain SAC3_GANP PF03399.16 KPI44725.1 - 0.045 13.1 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 SAC3/GANP family MIP PF00230.20 KPI44727.1 - 1.8e-42 145.6 10.7 7e-24 84.8 1.2 2.1 1 1 1 2 2 2 2 Major intrinsic protein ArabFuran-catal PF09206.11 KPI44728.1 - 0.0009 18.6 3.1 0.0011 18.3 2.9 1.2 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic LMBR1 PF04791.16 KPI44728.1 - 0.83 8.5 3.4 0.92 8.3 3.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR_4 PF12799.7 KPI44730.1 - 0.52 10.8 3.5 65 4.2 0.3 4.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) ABM PF03992.16 KPI44731.1 - 2e-05 24.6 0.2 3.2e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PUA PF01472.20 KPI44732.1 - 4.9e-16 58.4 0.1 9.3e-16 57.6 0.1 1.4 1 1 0 1 1 1 1 PUA domain Myosin_N PF02736.19 KPI44732.1 - 0.092 12.6 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF4443 PF14544.6 KPI44732.1 - 0.097 12.9 0.0 0.23 11.7 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4443) F-box-like PF12937.7 KPI44733.1 - 1.7e-12 47.1 0.1 3.8e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KPI44733.1 - 3.6e-11 42.2 4.3 0.004 17.1 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich repeat F-box PF00646.33 KPI44733.1 - 6.4e-07 29.1 0.5 2.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KPI44733.1 - 0.02 15.3 16.9 0.75 10.3 0.1 6.4 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) Recep_L_domain PF01030.24 KPI44733.1 - 0.37 10.9 2.2 18 5.5 0.9 3.3 2 2 1 3 3 3 0 Receptor L domain LRR_1 PF00560.33 KPI44733.1 - 4.4 8.2 20.8 11 7.0 0.1 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat CDP-OH_P_transf PF01066.21 KPI44734.1 - 5.2e-13 49.6 0.7 5.2e-13 49.6 0.7 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase His_Phos_1 PF00300.22 KPI44735.1 - 6.3e-17 61.9 0.6 3.1e-16 59.6 0.0 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Baculo_p48 PF04878.13 KPI44735.1 - 0.028 13.4 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein NolB PF17398.2 KPI44735.1 - 0.1 13.0 0.5 0.1 13.0 0.5 2.5 3 0 0 3 3 3 0 Nodulation protein NolB Amidohydro_1 PF01979.20 KPI44737.1 - 7e-70 236.0 0.0 8.2e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI44737.1 - 5.4e-05 22.9 3.5 0.0032 17.0 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family MmgE_PrpD PF03972.14 KPI44739.1 - 3e-103 345.7 0.2 3.4e-103 345.5 0.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nuc_sug_transp PF04142.15 KPI44741.1 - 5.7e-10 38.9 0.3 1e-09 38.0 0.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KPI44741.1 - 4.4e-09 36.6 23.1 0.00012 22.3 2.0 2.8 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 KPI44741.1 - 7.7e-05 22.2 6.3 0.00035 20.0 0.4 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KPI44741.1 - 0.0029 16.9 8.3 0.0029 16.9 8.3 1.7 2 0 0 2 2 2 1 UAA transporter family Med18 PF09637.10 KPI44742.1 - 5.7e-26 91.9 0.0 6.9e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein MARVEL PF01284.23 KPI44744.1 - 0.02 14.9 27.0 0.057 13.4 25.2 2.0 1 1 1 2 2 2 0 Membrane-associating domain DUF417 PF04224.12 KPI44744.1 - 0.1 12.1 2.4 8.4 5.9 1.8 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF417 DUF4574 PF15141.6 KPI44744.1 - 0.13 12.1 0.5 0.33 10.9 0.5 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF4175 PF13779.6 KPI44744.1 - 5.6 4.7 5.3 8.3 4.2 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sas10_Utp3 PF04000.15 KPI44745.1 - 1.2e-16 61.1 0.1 3.9e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HET PF06985.11 KPI44746.1 - 7.6e-12 45.8 6.5 3.5e-10 40.4 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.18 KPI44747.1 - 2.4e-09 37.1 2.8 2.4e-09 37.1 2.8 3.1 3 1 0 3 3 3 2 MYND finger Mcp5_PH PF12814.7 KPI44747.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF3253 PF11625.8 KPI44747.1 - 0.58 10.4 2.6 7.7 6.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) zf-C6H2 PF15801.5 KPI44747.1 - 0.78 10.1 9.4 1.8 8.9 3.6 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Glutaredoxin PF00462.24 KPI44748.1 - 1.1e-19 70.3 0.0 1.7e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KPI44748.1 - 0.002 18.5 0.0 0.0026 18.1 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KPI44748.1 - 0.0046 17.4 0.1 0.012 16.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_2 PF13409.6 KPI44748.1 - 0.036 14.4 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 KPI44748.1 - 0.039 13.9 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 KPI44748.1 - 0.039 14.4 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4124 PF13511.6 KPI44748.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) IBR PF01485.21 KPI44750.1 - 0.14 12.4 2.0 0.26 11.6 2.0 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Cwf_Cwc_15 PF04889.12 KPI44750.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MBOAT PF03062.19 KPI44751.1 - 2.1e-46 158.9 0.3 4.4e-46 157.8 0.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Csm4_C PF17953.1 KPI44751.1 - 0.19 11.6 0.1 0.59 10.0 0.0 1.7 2 0 0 2 2 2 0 CRISPR Csm4 C-terminal domain DUF983 PF06170.12 KPI44751.1 - 1.5 9.3 5.3 0.51 10.8 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Polyketide_cyc PF03364.20 KPI44752.1 - 0.0041 17.3 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KPI44752.1 - 0.034 14.4 1.7 0.052 13.8 0.2 2.0 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DnaJ PF00226.31 KPI44753.1 - 5.6e-24 84.0 0.4 1.6e-23 82.6 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KPI44753.1 - 9.7e-11 41.7 4.4 1.2e-10 41.4 2.2 2.2 1 1 1 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KPI44753.1 - 9.9e-10 38.5 1.2 9.9e-10 38.5 1.2 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KPI44753.1 - 2.9e-07 30.8 2.8 0.0011 19.3 1.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KPI44753.1 - 1e-05 25.7 5.5 0.0068 16.8 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI44753.1 - 2.3e-05 24.8 3.6 0.18 12.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KPI44753.1 - 0.00056 20.3 2.4 0.34 11.4 0.0 3.6 4 0 0 4 4 3 2 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.6 KPI44753.1 - 0.085 12.9 4.5 0.51 10.4 0.2 2.9 3 0 0 3 3 3 0 CpXC protein zf-C2H2_3rep PF18868.1 KPI44753.1 - 0.14 12.8 1.4 11 6.7 0.0 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KPI44753.1 - 0.22 11.7 4.1 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.11 KPI44753.1 - 0.7 9.8 5.4 3.1 7.8 0.7 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KPI44753.1 - 0.84 9.7 5.4 8 6.6 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2175 PF09943.9 KPI44753.1 - 3.7 7.9 5.9 21 5.5 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Med10 PF09748.9 KPI44754.1 - 9.6e-31 106.3 0.1 2.1e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KPI44754.1 - 0.18 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4267 PF14087.6 KPI44755.1 - 5.5e-12 45.8 0.1 7.2e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) CLP1_P PF16575.5 KPI44756.1 - 6.1e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CorA PF01544.18 KPI44757.1 - 0.0072 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-RING_2 PF13639.6 KPI44758.1 - 2.6e-11 43.6 6.8 2.6e-11 43.6 6.8 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI44758.1 - 1.6e-07 31.0 7.0 1.6e-07 31.0 7.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI44758.1 - 3e-07 30.1 5.7 6.4e-07 29.0 5.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger Fungal_trans_2 PF11951.8 KPI44758.1 - 4.5e-07 29.0 9.5 1.5e-06 27.3 9.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_UBOX PF13445.6 KPI44758.1 - 3.1e-06 27.1 6.8 9.6e-06 25.5 6.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI44758.1 - 4.2e-06 26.5 6.2 4.2e-06 26.5 6.2 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI44758.1 - 4.2e-05 23.4 4.3 0.00012 21.9 4.3 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KPI44758.1 - 6.7e-05 23.1 7.2 0.00037 20.7 7.2 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KPI44758.1 - 0.0009 19.0 5.8 0.0028 17.5 5.8 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KPI44758.1 - 0.0022 18.0 4.0 0.0058 16.7 1.1 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KPI44758.1 - 0.0073 16.1 3.4 0.018 14.9 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PSI_integrin PF17205.3 KPI44758.1 - 0.029 14.1 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 Integrin plexin domain LapA_dom PF06305.11 KPI44758.1 - 0.058 13.2 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-C3H2C3 PF17122.5 KPI44758.1 - 0.075 13.1 2.0 0.24 11.5 2.0 1.9 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KPI44758.1 - 0.11 12.2 2.0 0.28 10.8 2.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KPI44758.1 - 0.12 12.5 1.8 0.33 11.2 1.8 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 KPI44758.1 - 0.16 11.9 2.0 3 7.8 3.1 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KPI44758.1 - 0.98 9.3 11.8 0.22 11.4 4.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KPI44758.1 - 3.3 8.1 7.9 0.45 10.9 2.6 2.4 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.6 KPI44758.1 - 9.7 6.4 15.2 0.18 12.0 7.6 2.2 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Sugar_tr PF00083.24 KPI44760.1 - 2.1e-133 445.5 26.4 2.4e-133 445.3 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44760.1 - 7.1e-25 87.7 53.2 7.7e-22 77.7 29.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KPI44761.1 - 6.3e-47 160.4 0.0 8.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 KPI44761.1 - 1.1e-10 42.4 1.7 3e-10 40.9 1.7 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF756 PF05506.12 KPI44761.1 - 0.21 12.5 1.2 1.3 10.0 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF756) Hydrolase_4 PF12146.8 KPI44763.1 - 0.017 14.4 0.0 0.75 9.0 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPI44763.1 - 0.098 12.1 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KPI44763.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Sugar_tr PF00083.24 KPI44764.1 - 6.1e-85 285.8 21.7 7.1e-85 285.5 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44764.1 - 2.6e-19 69.4 30.8 4.8e-19 68.5 24.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rpn3_C PF08375.11 KPI44765.1 - 2.7e-26 91.8 1.6 7.1e-26 90.4 1.6 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KPI44765.1 - 3.4e-12 46.8 0.2 3.4e-11 43.6 0.1 2.4 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KPI44765.1 - 0.1 12.6 0.3 0.44 10.5 0.3 2.1 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family DUF1202 PF06717.11 KPI44767.1 - 0.15 11.4 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) CSN8_PSD8_EIF3K PF10075.9 KPI44768.1 - 3.4e-42 143.8 0.0 1e-41 142.3 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family AMP-binding PF00501.28 KPI44768.1 - 2.9e-26 92.0 0.0 1.3e-25 89.9 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme DUF951 PF06107.11 KPI44768.1 - 0.02 14.8 0.1 0.046 13.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) EHN PF06441.12 KPI44769.1 - 4.2e-29 101.1 0.2 7.4e-29 100.3 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KPI44769.1 - 3.2e-10 40.1 0.0 5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44769.1 - 0.035 14.7 5.1 0.13 12.9 5.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2183 PF09949.9 KPI44770.1 - 1e-33 115.6 0.0 3.2e-33 114.0 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SecE PF00584.20 KPI44771.1 - 6.1e-14 51.7 0.0 7.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Glucan_synthase PF02364.15 KPI44772.1 - 0 1396.7 0.0 0 1396.0 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KPI44772.1 - 4.9e-44 149.8 0.7 1.6e-43 148.1 0.7 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 KPI44772.1 - 4.5e-35 121.5 0.0 6.4e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KPI44772.1 - 0.015 13.8 0.1 0.027 13.0 0.1 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme tRNA_m1G_MT PF01746.21 KPI44774.1 - 3.2e-23 82.5 2.3 1.1e-17 64.4 0.0 2.5 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase TRP PF06011.12 KPI44775.1 - 7.3e-130 433.5 36.6 1.8e-93 313.6 23.6 3.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KPI44775.1 - 8e-39 133.2 0.2 1.3e-38 132.5 0.2 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KPI44775.1 - 9.3e-05 22.9 0.0 0.00015 22.2 0.0 1.3 1 0 0 1 1 1 1 ML domain PT-VENN PF04829.13 KPI44775.1 - 9.5 6.4 7.0 28 4.9 7.0 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif IATP PF04568.12 KPI44776.1 - 1.4e-18 67.1 5.3 1.9e-12 47.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ATPase inhibitor, IATP SOGA PF11365.8 KPI44776.1 - 0.006 17.7 0.3 0.021 15.9 0.3 1.8 1 1 0 1 1 1 1 Protein SOGA NRBF2 PF08961.10 KPI44776.1 - 0.012 15.3 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator BLOC1_2 PF10046.9 KPI44776.1 - 0.048 14.0 0.8 0.094 13.0 0.8 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KPI44776.1 - 0.064 13.8 0.5 0.12 12.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DAO PF01266.24 KPI44777.1 - 6.9e-32 111.4 0.2 8.1e-32 111.2 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KPI44777.1 - 0.0015 18.7 0.1 0.0045 17.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KPI44777.1 - 0.0031 16.7 0.0 0.0047 16.1 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPI44777.1 - 0.0036 16.6 0.1 0.0066 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KPI44777.1 - 0.0057 16.7 0.1 0.015 15.3 0.2 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI44777.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI44777.1 - 0.053 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KPI44777.1 - 0.063 11.8 0.0 0.24 9.9 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) RRM_1 PF00076.22 KPI44778.1 - 1.7e-08 34.2 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KPI44778.1 - 0.00071 19.2 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_20 PF00982.21 KPI44779.1 - 7.5e-128 427.2 0.0 1.1e-118 396.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KPI44779.1 - 7.3e-65 218.3 0.0 1.4e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Cutinase PF01083.22 KPI44780.1 - 3.3e-24 85.8 0.4 3.3e-24 85.8 0.4 1.7 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.11 KPI44780.1 - 0.042 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Sporozoite_P67 PF05642.11 KPI44780.1 - 0.19 9.8 8.6 0.27 9.3 8.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SpoIIIAH PF12685.7 KPI44780.1 - 0.54 10.1 6.2 0.86 9.4 6.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Med3 PF11593.8 KPI44780.1 - 3.8 6.6 17.1 5.6 6.0 17.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TRI12 PF06609.13 KPI44781.1 - 1.6e-32 112.7 15.1 4.8e-32 111.2 14.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KPI44781.1 - 4.7e-09 35.6 44.3 4.7e-09 35.6 44.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44781.1 - 1.3e-06 27.6 8.2 1.3e-06 27.6 8.2 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter Trypan_PARP PF05887.11 KPI44782.1 - 0.031 14.3 55.2 0.035 14.1 14.4 3.7 2 1 2 4 4 4 0 Procyclic acidic repetitive protein (PARP) RNA_pol_Rpb1_5 PF04998.17 KPI44783.1 - 2.6e-74 250.1 0.1 4.4e-74 249.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KPI44783.1 - 2.1e-72 242.8 0.3 4.9e-72 241.6 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KPI44783.1 - 7.3e-63 212.8 0.0 1.3e-62 211.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KPI44783.1 - 8.6e-37 126.5 0.0 1.8e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KPI44783.1 - 1.6e-27 95.6 0.3 4.8e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Mucin PF01456.17 KPI44783.1 - 0.64 10.0 9.6 11 6.0 5.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PH PF00169.29 KPI44784.1 - 8.3e-11 42.3 0.3 3.1e-10 40.5 0.0 2.2 2 1 0 2 2 2 1 PH domain SH3_9 PF14604.6 KPI44784.1 - 6.4e-10 38.7 0.1 1.5e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI44784.1 - 2.6e-08 33.3 0.0 5.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 KPI44784.1 - 7.5e-08 32.4 0.1 1.2e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KPI44784.1 - 0.00084 19.7 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 KPI44784.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 KPI44784.1 - 0.031 14.7 0.1 0.056 13.9 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KPI44784.1 - 0.047 14.0 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4648 PF15505.6 KPI44784.1 - 0.061 14.2 0.4 0.38 11.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) DUF1195 PF06708.11 KPI44787.1 - 0.22 11.3 1.5 0.38 10.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Cuticle_1 PF08140.11 KPI44789.1 - 0.036 14.1 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Crustacean cuticle protein repeat TPR_2 PF07719.17 KPI44790.1 - 1.4e-25 87.2 25.5 0.027 14.6 0.4 14.8 18 0 0 18 18 16 6 Tetratricopeptide repeat TPR_19 PF14559.6 KPI44790.1 - 2.8e-24 85.4 37.0 2.7e-07 31.0 1.7 10.6 8 3 3 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KPI44790.1 - 5.1e-21 75.0 42.7 6.3e-06 26.7 0.7 12.8 12 3 2 14 14 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 KPI44790.1 - 1.1e-20 72.5 16.8 0.016 15.0 0.0 12.0 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 KPI44790.1 - 1.2e-19 68.8 23.5 0.0093 16.1 0.1 14.1 18 0 0 18 18 15 5 Tetratricopeptide repeat TPR_11 PF13414.6 KPI44790.1 - 1.9e-19 69.1 13.3 0.00013 21.5 0.0 10.7 8 2 2 10 10 10 4 TPR repeat TPR_14 PF13428.6 KPI44790.1 - 8.5e-19 66.6 40.0 0.16 12.9 0.0 16.0 13 4 6 19 19 16 6 Tetratricopeptide repeat TPR_17 PF13431.6 KPI44790.1 - 1.6e-18 65.6 19.3 0.023 15.1 0.3 13.3 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_9 PF13371.6 KPI44790.1 - 3.2e-18 65.6 8.1 0.011 15.8 0.1 8.2 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KPI44790.1 - 1.2e-16 60.7 28.0 0.00047 20.4 0.4 11.7 10 3 4 14 14 14 8 Tetratricopeptide repeat TPR_7 PF13176.6 KPI44790.1 - 4.1e-07 29.6 21.1 0.072 13.1 0.0 10.3 11 1 1 12 12 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KPI44790.1 - 4.1e-05 23.7 12.9 0.66 10.2 0.1 6.8 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KPI44790.1 - 5.2e-05 23.6 17.3 45 5.0 0.3 11.3 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 KPI44790.1 - 0.0061 16.9 26.2 0.13 12.6 0.5 7.3 6 2 1 7 7 6 2 Tetratricopeptide repeat Clathrin PF00637.20 KPI44790.1 - 0.0068 16.3 3.2 0.41 10.5 0.0 4.0 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_4 PF07721.14 KPI44790.1 - 0.036 14.7 24.6 6 7.8 0.0 10.6 12 0 0 12 12 10 0 Tetratricopeptide repeat RPN6_N PF18055.1 KPI44790.1 - 0.094 13.1 1.6 0.63 10.4 0.3 3.0 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_10 PF13374.6 KPI44790.1 - 0.17 11.8 17.1 10 6.2 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 KPI44791.1 - 0.0007 19.5 6.0 0.0012 18.7 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KPI44791.1 - 0.0069 16.4 7.7 0.015 15.3 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI44791.1 - 0.0099 15.7 2.7 0.021 14.7 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI44791.1 - 0.039 14.3 5.7 0.07 13.5 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KPI44791.1 - 0.04 13.8 7.1 0.071 13.0 7.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LPP20 PF02169.16 KPI44791.1 - 0.99 9.8 3.5 1.1 9.6 1.5 2.1 2 0 0 2 2 2 0 LPP20 lipoprotein YdjO PF14169.6 KPI44792.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO DUF5427 PF10310.9 KPI44793.1 - 2.7e-147 491.5 3.3 3.5e-141 471.4 0.1 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KPI44793.1 - 0.37 11.0 2.0 2.1 8.6 0.1 2.7 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain COesterase PF00135.28 KPI44794.1 - 1.6e-82 278.1 0.0 1.2e-66 225.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI44794.1 - 0.0013 18.7 0.3 0.0023 17.8 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold UQ_con PF00179.26 KPI44795.1 - 7.1e-43 145.6 0.0 8.2e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPI44795.1 - 7.5e-07 28.9 0.0 9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPI44795.1 - 0.037 14.3 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain PRANC PF09372.10 KPI44796.1 - 0.048 14.0 0.4 0.12 12.7 0.1 1.9 3 0 0 3 3 3 0 PRANC domain TerB PF05099.13 KPI44796.1 - 0.089 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB THOC7 PF05615.13 KPI44798.1 - 1.1e-21 77.5 3.0 1.3e-21 77.2 2.2 1.6 1 1 0 1 1 1 1 Tho complex subunit 7 CEP63 PF17045.5 KPI44798.1 - 0.067 13.1 4.9 0.2 11.6 4.9 1.8 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Lectin_N PF03954.14 KPI44798.1 - 0.08 12.7 0.7 0.15 11.8 0.7 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain HalX PF08663.10 KPI44798.1 - 1 9.7 5.1 1.2 9.5 0.4 2.9 2 1 0 2 2 2 0 HalX domain MtrF PF09472.10 KPI44799.1 - 0.028 13.8 0.7 0.053 12.9 0.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AFG1_ATPase PF03969.16 KPI44799.1 - 0.074 11.9 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 AFG1-like ATPase GTP_EFTU PF00009.27 KPI44801.1 - 9.7e-47 159.0 0.0 1.6e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KPI44801.1 - 5.5e-37 127.1 7.9 1.1e-36 126.1 7.9 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KPI44801.1 - 9.7e-25 86.7 0.0 3.5e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KPI44801.1 - 6.3e-18 64.6 0.0 2e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KPI44801.1 - 5.9e-06 26.3 0.0 1.7e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KPI44801.1 - 6e-06 26.5 0.0 1.8e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KPI44801.1 - 0.00023 21.2 0.1 0.00056 20.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KPI44801.1 - 0.034 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras family Septin PF00735.18 KPI44801.1 - 0.078 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin Acyltransferase PF01553.21 KPI44802.1 - 6.7e-16 58.1 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KPI44802.1 - 0.0022 18.0 0.8 0.0068 16.5 0.3 2.1 2 0 0 2 2 2 1 Acyltransferase C-terminus Lectin_C_term PF18022.1 KPI44802.1 - 0.078 13.5 0.3 0.16 12.5 0.3 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain ThiF PF00899.21 KPI44803.1 - 2.2e-65 220.4 0.0 3e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KPI44803.1 - 4.5e-28 97.2 0.1 7.9e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KPI44803.1 - 0.00014 21.9 0.4 0.00044 20.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UPF0052 PF01933.18 KPI44803.1 - 0.083 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Pyr_redox PF00070.27 KPI44803.1 - 0.093 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 KPI44803.1 - 0.095 13.4 0.1 0.21 12.3 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 KPI44803.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KPI44803.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KPI44803.1 - 0.2 11.9 1.3 0.46 10.7 0.1 2.3 3 1 1 4 4 4 0 Saccharopine dehydrogenase NADP binding domain Ecm33 PF12454.8 KPI44803.1 - 0.31 11.2 3.8 0.65 10.2 3.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein DUF4336 PF14234.6 KPI44805.1 - 3.7e-10 39.5 0.8 7e-05 22.2 0.1 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Elongin_A PF06881.11 KPI44806.1 - 2.3e-13 50.6 8.9 1.5e-07 31.9 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.16 KPI44807.1 - 4.2e-19 68.7 31.7 5.2e-15 55.2 35.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATP-synt_E PF05680.12 KPI44807.1 - 0.0044 17.3 0.5 0.0044 17.3 0.5 1.8 2 0 0 2 2 2 1 ATP synthase E chain RRF PF01765.19 KPI44808.1 - 7.1e-32 110.6 0.7 1.3e-31 109.8 0.7 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Atg14 PF10186.9 KPI44808.1 - 0.0018 17.4 1.0 0.0042 16.2 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 7tm_2 PF00002.24 KPI44809.1 - 3.7e-08 33.0 7.7 5.5e-08 32.4 7.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KPI44809.1 - 0.0017 17.5 4.6 0.0037 16.4 4.1 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor DUF4328 PF14219.6 KPI44809.1 - 4.8 6.7 9.7 7.6 6.0 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) Cyclin PF08613.11 KPI44810.1 - 2.5e-33 115.8 0.0 4e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin AlaDh_PNT_N PF05222.15 KPI44810.1 - 0.083 13.2 0.0 20 5.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain Cyclin_N PF00134.23 KPI44810.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L31 PF01197.18 KPI44811.1 - 0.00059 20.0 0.0 0.002 18.3 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L31 Ribosomal_L37ae PF01780.19 KPI44811.1 - 0.14 12.3 0.1 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L37ae protein family p450 PF00067.22 KPI44812.1 - 1.7e-49 168.9 0.0 2.1e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3390 PF11870.8 KPI44812.1 - 0.02 15.3 0.2 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) F-box-like PF12937.7 KPI44813.1 - 0.011 15.6 0.2 0.043 13.7 0.1 2.1 2 1 0 2 2 2 0 F-box-like Glyco_hydro_43 PF04616.14 KPI44814.1 - 2.6e-64 217.3 1.5 1e-34 120.2 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KPI44814.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain GPI-anchored PF10342.9 KPI44815.1 - 1.4e-13 51.4 0.7 1.4e-13 51.4 0.7 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KPI44815.1 - 0.59 9.3 12.2 0.59 9.3 12.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein UQ_con PF00179.26 KPI44816.1 - 3.4e-26 91.6 0.2 7.6e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPI44816.1 - 0.00075 19.2 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 KPI44816.1 - 0.0041 17.0 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 UEV domain Occludin_ELL PF07303.13 KPI44816.1 - 0.036 14.8 0.2 0.098 13.4 0.2 1.6 1 0 0 1 1 1 0 Occludin homology domain Fungal_trans PF04082.18 KPI44817.1 - 0.0037 16.3 0.4 0.0037 16.3 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MscS_porin PF12795.7 KPI44817.1 - 0.68 9.4 7.4 0.098 12.2 0.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain YgaB PF14182.6 KPI44818.1 - 0.0038 17.6 0.8 0.01 16.2 0.8 1.7 1 0 0 1 1 1 1 YgaB-like protein DUF1664 PF07889.12 KPI44818.1 - 0.081 13.0 1.6 0.13 12.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KPI44818.1 - 4 6.0 7.3 0.64 8.6 3.0 1.4 1 1 0 1 1 1 0 AAA domain HET PF06985.11 KPI44819.1 - 5.9e-27 94.8 1.3 5.9e-27 94.8 1.3 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N_2 PF13602.6 KPI44820.1 - 0.0013 19.8 0.2 0.003 18.6 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AAA PF00004.29 KPI44821.1 - 1.8e-50 170.8 0.0 2.7e-42 144.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI44821.1 - 6.1e-10 38.7 0.0 1.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KPI44821.1 - 7.2e-08 33.0 0.4 4.7e-05 23.8 0.0 3.7 4 0 0 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KPI44821.1 - 1.4e-07 31.4 0.0 4.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KPI44821.1 - 9e-06 25.9 0.0 3e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KPI44821.1 - 0.00027 20.9 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI44821.1 - 0.00073 19.8 0.2 0.047 14.0 0.2 3.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KPI44821.1 - 0.0021 18.4 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KPI44821.1 - 0.0033 17.0 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KPI44821.1 - 0.0082 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KPI44821.1 - 0.0096 16.5 0.0 0.054 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KPI44821.1 - 0.0099 15.6 0.0 1.7 8.3 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.6 KPI44821.1 - 0.011 15.5 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KPI44821.1 - 0.012 16.1 0.0 0.054 14.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KPI44821.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KPI44821.1 - 0.014 15.6 0.2 0.05 13.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KPI44821.1 - 0.018 14.4 0.1 0.083 12.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KPI44821.1 - 0.018 15.1 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Torsin RuvB_N PF05496.12 KPI44821.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KPI44821.1 - 0.045 13.3 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KPI44821.1 - 0.048 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 KPI44821.1 - 0.054 13.6 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Bromodomain PF00439.25 KPI44821.1 - 0.082 13.0 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Bromodomain Parvo_NS1 PF01057.17 KPI44821.1 - 0.089 11.9 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KPI44821.1 - 0.098 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KPI44821.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 KPI44821.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KPI44821.1 - 0.25 11.1 5.3 0.36 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain CCDC158 PF15921.5 KPI44822.1 - 0.013 13.4 0.3 0.017 13.0 0.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 FlxA PF14282.6 KPI44822.1 - 8 6.5 9.2 0.6 10.1 3.9 1.9 2 0 0 2 2 2 0 FlxA-like protein Scytalone_dh PF02982.14 KPI44823.1 - 3.6e-84 280.4 3.3 4.3e-84 280.1 3.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KPI44823.1 - 9.5e-08 32.2 0.3 1.3e-07 31.8 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Cupin_7 PF12973.7 KPI44824.1 - 4.9e-09 36.0 0.1 5.8e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.6 KPI44824.1 - 0.00064 18.9 0.0 0.00072 18.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_2 PF07883.11 KPI44824.1 - 0.0039 16.9 0.4 0.007 16.1 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Autoind_bind PF03472.15 KPI44824.1 - 0.068 12.6 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Autoinducer binding domain Complex1_LYR_2 PF13233.6 KPI44825.1 - 2.1e-05 25.2 1.3 2.6e-05 24.9 1.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KPI44825.1 - 8.1e-05 22.6 0.1 0.00013 22.0 0.1 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DUF3135 PF11333.8 KPI44825.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Nrap_D5 PF17406.2 KPI44826.1 - 0.16 11.7 0.5 6.2 6.6 0.4 2.4 2 0 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 ATP-synt_E PF05680.12 KPI44826.1 - 2.1 8.7 10.2 0.44 10.9 1.9 2.9 3 0 0 3 3 3 0 ATP synthase E chain Mito_carr PF00153.27 KPI44828.1 - 3.1e-44 148.8 7.2 2.1e-17 62.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DRMBL PF07522.14 KPI44830.1 - 2.7e-30 104.8 0.0 5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KPI44830.1 - 0.00019 21.0 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 KPI44832.1 - 3.8e-31 108.3 34.4 5e-31 107.9 34.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF543 PF04418.12 KPI44833.1 - 2.6e-27 94.6 0.0 3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Mito_carr PF00153.27 KPI44835.1 - 1.6e-42 143.4 3.8 5.4e-21 74.3 0.1 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein Serine_protease PF18405.1 KPI44835.1 - 0.19 10.9 0.4 0.79 8.8 0.0 2.1 2 1 0 2 2 2 0 Gammaproteobacterial serine protease SPO22 PF08631.10 KPI44836.1 - 7.1e-30 104.4 6.6 2.8e-27 95.9 0.4 3.8 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KPI44836.1 - 0.18 12.1 7.6 0.13 12.5 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_His PF13393.6 KPI44837.1 - 1.9e-35 122.7 0.0 1.2e-29 103.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KPI44837.1 - 0.00014 21.9 0.1 0.00033 20.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain CVNH PF08881.10 KPI44838.1 - 9.8e-25 87.2 0.3 1.8e-24 86.4 0.3 1.4 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.15 KPI44838.1 - 3.7e-05 23.5 12.2 3.7e-05 23.5 12.2 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KPI44838.1 - 0.011 15.8 11.1 0.011 15.8 11.1 2.2 2 0 0 2 2 2 0 Glycine zipper Ebp2 PF05890.12 KPI44838.1 - 0.011 15.3 11.3 0.019 14.5 11.3 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 SR-25 PF10500.9 KPI44838.1 - 0.044 13.4 17.5 0.086 12.4 17.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 KPI44838.1 - 0.091 12.0 0.5 0.15 11.2 0.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF533 PF04391.12 KPI44838.1 - 0.14 11.7 0.5 0.35 10.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TFIIF_alpha PF05793.12 KPI44838.1 - 0.31 9.6 11.5 0.47 9.0 11.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4692 PF15763.5 KPI44838.1 - 0.73 10.3 4.9 1.8 9.0 4.9 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CCDC106 PF15794.5 KPI44838.1 - 0.85 9.3 9.2 1.6 8.4 9.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Rtf2 PF04641.12 KPI44838.1 - 3.3 7.0 9.5 4.9 6.4 9.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_4 PF13894.6 KPI44840.1 - 0.0099 16.7 0.5 0.47 11.4 0.0 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger ADH_zinc_N PF00107.26 KPI44841.1 - 5.3e-13 49.1 0.6 9.2e-13 48.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI44841.1 - 2e-09 38.6 0.0 3.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI44841.1 - 3.3e-09 36.6 0.2 2.8e-07 30.4 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KPI44841.1 - 0.018 14.4 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPI44841.1 - 0.11 11.8 0.9 0.17 11.2 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EthD PF07110.11 KPI44842.1 - 1e-21 77.9 0.0 4e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 EthD domain MmlI PF09448.10 KPI44842.1 - 9.5e-15 55.0 0.0 1.8e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Methylmuconolactone methyl-isomerase NT5C PF06941.12 KPI44842.1 - 0.11 12.3 0.1 5.5 6.8 0.0 2.2 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF4449 PF14613.6 KPI44843.1 - 1.6e-06 28.3 4.9 5.2e-06 26.7 0.1 3.4 2 2 1 3 3 3 1 Protein of unknown function (DUF4449) SbsC_C PF18058.1 KPI44843.1 - 0.0039 17.4 0.7 0.018 15.2 0.7 2.1 2 0 0 2 2 2 1 SbsC C-terminal domain LBP_BPI_CETP PF01273.25 KPI44843.1 - 0.029 14.0 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Tricorn_C1 PF14684.6 KPI44843.1 - 0.27 11.3 1.1 2.4 8.3 0.2 2.7 2 1 1 3 3 3 0 Tricorn protease C1 domain G6PD_C PF02781.16 KPI44844.1 - 7.6e-115 383.1 0.0 1.3e-114 382.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KPI44844.1 - 1.7e-61 207.9 0.0 3.1e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KPI44847.1 - 4.4e-75 253.3 26.9 1.3e-72 245.2 26.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI44847.1 - 9.1e-19 67.6 29.5 1.6e-18 66.8 11.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 KPI44848.1 - 4.3e-05 23.9 0.2 0.0011 19.3 0.2 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Prim_Zn_Ribbon PF08273.12 KPI44848.1 - 0.1 12.9 1.2 2.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Fungal_trans PF04082.18 KPI44850.1 - 1.5e-13 50.4 0.5 3.2e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI44850.1 - 4.3e-05 23.5 6.2 8.7e-05 22.6 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_130 PF04041.13 KPI44851.1 - 1.1e-36 126.4 0.0 2.1e-36 125.5 0.0 1.4 1 1 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 KPI44851.1 - 2.6e-08 33.5 0.3 0.00018 20.9 0.2 3.2 3 1 0 3 3 3 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KPI44851.1 - 1.4e-07 31.4 0.5 6.5e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.11 KPI44852.1 - 1.7e-31 109.5 4.7 3e-31 108.7 4.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.22 KPI44854.1 - 2.6e-53 179.9 0.3 2.4e-52 176.8 0.3 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KPI44854.1 - 2.5e-19 69.7 0.0 1.2e-17 64.2 0.0 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI44854.1 - 0.00016 21.2 0.0 0.00078 18.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KPI44854.1 - 0.03 14.2 0.0 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KPI44854.1 - 0.058 12.7 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KPI44854.1 - 0.072 12.6 0.0 1.1 8.8 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 KPI44854.1 - 0.12 11.9 0.2 1.4 8.4 0.2 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 KPI44854.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nfu_N PF08712.11 KPI44855.1 - 4.1e-28 97.3 0.0 2e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KPI44855.1 - 7.2e-26 90.1 0.0 1.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KPI44855.1 - 0.12 12.5 0.6 0.26 11.4 0.6 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus GAT PF03127.14 KPI44856.1 - 0.24 11.7 2.3 0.75 10.1 0.3 2.7 2 1 0 2 2 2 0 GAT domain DUF1664 PF07889.12 KPI44856.1 - 0.26 11.3 2.9 2 8.4 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Flagellin_C PF00700.21 KPI44856.1 - 0.84 10.0 8.0 3.9 7.9 0.1 3.1 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region Pyr_redox_2 PF07992.14 KPI44858.1 - 1.2e-17 64.1 0.1 1.5e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI44858.1 - 1.4e-05 25.1 2.2 0.059 13.3 0.0 2.6 2 1 1 3 3 3 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KPI44858.1 - 0.0032 16.8 0.5 0.45 9.8 0.0 2.1 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KPI44858.1 - 0.053 12.9 0.6 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KPI44858.1 - 0.1 13.2 7.7 2.9 8.5 1.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KPI44858.1 - 0.11 12.9 2.3 0.32 11.5 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding P53_TAD PF08563.11 KPI44859.1 - 0.0053 16.2 0.3 0.013 15.0 0.3 1.7 1 0 0 1 1 1 1 P53 transactivation motif EthD PF07110.11 KPI44860.1 - 1.6e-16 61.3 1.2 2.1e-16 60.8 1.2 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KPI44860.1 - 4.9e-07 30.2 0.2 6.7e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DHHC PF01529.20 KPI44861.1 - 5.2e-05 23.4 0.4 6.9e-05 23.0 0.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cadherin_C_2 PF16492.5 KPI44861.1 - 0.12 13.2 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Ferritin_2 PF13668.6 KPI44862.1 - 1.4e-07 31.7 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Babuvirus_MP PF07234.11 KPI44862.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Movement and RNA silencing protein Xpo1 PF08389.12 KPI44863.1 - 3.2e-35 121.4 4.8 6.9e-35 120.3 0.6 3.6 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KPI44863.1 - 0.0046 17.1 2.1 19 5.8 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat TetR_C_33 PF13305.6 KPI44863.1 - 0.032 15.0 0.4 0.41 11.4 0.1 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain V-ATPase_H_N PF03224.14 KPI44863.1 - 0.95 8.7 4.9 9.1 5.5 0.1 3.8 4 2 0 4 4 4 0 V-ATPase subunit H MFS_1 PF07690.16 KPI44864.1 - 2.2e-26 92.6 38.8 1.7e-25 89.8 39.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 KPI44864.1 - 0.022 15.1 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Fungal_trans_2 PF11951.8 KPI44865.1 - 3.4e-05 22.8 0.1 5.6e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C3H2C3 PF17122.5 KPI44866.1 - 0.00042 20.3 0.0 0.00042 20.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 KPI44866.1 - 0.018 15.0 2.9 0.066 13.2 0.8 2.3 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 KPI44866.1 - 0.023 14.5 0.2 0.05 13.4 0.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KPI44866.1 - 0.033 14.2 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger TilS PF09179.11 KPI44866.1 - 0.053 14.0 0.4 20 5.8 0.0 2.8 2 0 0 2 2 2 0 TilS substrate binding domain zf-RING_2 PF13639.6 KPI44866.1 - 0.79 10.1 5.5 0.25 11.7 1.3 2.3 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KPI44866.1 - 0.89 9.4 0.0 0.89 9.4 0.0 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RRN7 PF11781.8 KPI44866.1 - 1.1 9.1 4.1 2.3 8.0 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4448 PF14610.6 KPI44867.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KPI44867.1 - 0.011 15.2 1.9 0.021 14.2 1.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.16 KPI44868.1 - 1.3e-13 50.6 24.7 1.9e-13 50.1 24.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI44868.1 - 4.3e-12 45.6 12.6 6.9e-12 45.0 12.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.9 KPI44868.1 - 0.025 15.0 1.2 0.069 13.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) SgrT PF15894.5 KPI44869.1 - 0.0069 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of glucose uptake transporter SgrT TspO_MBR PF03073.15 KPI44870.1 - 7.2e-42 142.7 6.2 3.7e-41 140.4 6.2 1.9 1 1 0 1 1 1 1 TspO/MBR family Tautomerase_3 PF14832.6 KPI44871.1 - 1.3e-12 48.1 0.4 1e-11 45.2 0.4 2.0 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 KPI44871.1 - 4.9e-06 26.4 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Tautomerase enzyme PA28_beta PF02252.18 KPI44871.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit zf-C2H2 PF00096.26 KPI44872.1 - 4.2e-09 36.4 3.8 2.7e-05 24.3 0.2 6.3 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI44872.1 - 0.0053 17.5 4.4 0.039 14.8 0.4 7.1 8 0 0 8 8 8 2 C2H2-type zinc finger FOXP-CC PF16159.5 KPI44872.1 - 0.0058 17.2 0.5 0.0058 17.2 0.5 6.2 5 2 3 8 8 8 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KPI44872.1 - 1.2 9.5 9.8 2.6 8.4 0.2 3.8 4 1 0 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KPI44872.1 - 2.8 8.0 8.6 22 5.1 1.6 3.0 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KPI44872.1 - 4.5 7.7 9.7 0.17 12.2 0.4 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Band_7 PF01145.25 KPI44873.1 - 4.7e-18 65.8 0.7 4.7e-18 65.8 0.7 2.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family FAD_binding_4 PF01565.23 KPI44874.1 - 1.7e-26 92.6 0.1 3.8e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KPI44874.1 - 2.7e-15 56.7 0.0 3.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain SRI PF08236.11 KPI44876.1 - 7.1e-20 71.0 13.2 7.1e-20 71.0 13.2 2.5 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KPI44876.1 - 1.9e-17 64.1 0.5 1.9e-17 64.1 0.5 3.9 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KPI44876.1 - 8.9e-10 38.4 13.6 2.1e-09 37.2 13.6 1.6 1 0 0 1 1 1 1 AWS domain TMEM171 PF15471.6 KPI44876.1 - 0.18 10.8 1.6 0.46 9.4 1.6 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Pox_H7 PF04787.12 KPI44876.1 - 7.2 7.1 8.2 0.83 10.2 3.6 1.7 2 0 0 2 2 2 0 Late protein H7 Abhydrolase_1 PF00561.20 KPI44877.1 - 1.8e-06 27.8 0.6 0.00044 20.0 0.1 2.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI44877.1 - 1.2e-05 24.7 0.0 6.9e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KPI44877.1 - 0.00016 21.3 0.0 0.27 10.7 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KPI44877.1 - 0.0013 18.3 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KPI44877.1 - 0.011 15.9 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 KPI44877.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 KPI44877.1 - 0.15 11.8 0.2 14 5.4 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.19 KPI44878.1 - 2.8e-23 82.7 0.2 2.3e-22 79.7 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KPI44878.1 - 0.00031 19.9 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KPI44878.1 - 0.0035 16.5 0.0 0.89 8.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KPI44878.1 - 0.034 14.1 0.1 0.14 12.2 0.1 2.0 1 1 1 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPI44878.1 - 0.094 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_hydro_16 PF00722.21 KPI44879.1 - 5.7e-17 61.7 2.2 1.1e-16 60.8 2.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Na_Ca_ex PF01699.24 KPI44880.1 - 3.7e-26 91.9 24.1 7.5e-15 55.2 8.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.12 KPI44880.1 - 0.0064 16.6 1.5 0.022 14.9 0.9 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) DUF4381 PF14316.6 KPI44882.1 - 0.0085 16.3 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) CcmD PF04995.14 KPI44882.1 - 0.046 13.8 0.4 0.08 13.0 0.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) GalKase_gal_bdg PF10509.9 KPI44882.1 - 0.052 13.1 0.2 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Galactokinase galactose-binding signature KDGP_aldolase PF07071.11 KPI44882.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 KDGP aldolase SSP160 PF06933.11 KPI44882.1 - 1.2 7.3 5.1 1.6 6.8 5.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.16 KPI44883.1 - 7.2e-31 107.4 28.3 7.2e-31 107.4 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5422 PF17459.2 KPI44883.1 - 0.41 10.8 4.0 1.9 8.6 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5422) DDHD PF02862.17 KPI44884.1 - 0.02 15.0 10.5 0.52 10.4 5.0 2.2 2 0 0 2 2 2 0 DDHD domain CAAP1 PF15335.6 KPI44884.1 - 0.36 11.4 1.5 8.1 7.1 0.1 3.2 2 1 1 3 3 3 0 Caspase activity and apoptosis inhibitor 1 SMC_N PF02463.19 KPI44885.1 - 2e-21 76.4 0.0 4.6e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KPI44885.1 - 2.1e-12 48.0 60.8 6.5e-10 39.8 33.2 5.1 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KPI44885.1 - 0.0015 18.3 5.9 0.0015 18.3 5.9 3.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KPI44885.1 - 0.0015 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 KPI44885.1 - 0.006 16.6 0.9 0.006 16.6 0.9 6.6 4 2 2 6 6 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KPI44885.1 - 0.023 14.0 0.5 0.023 14.0 0.5 6.5 4 1 1 6 6 5 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KPI44885.1 - 0.024 14.7 0.5 0.024 14.7 0.5 6.2 5 1 0 6 6 6 0 Laminin Domain II AAA_21 PF13304.6 KPI44885.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 KPI44885.1 - 0.15 11.6 0.0 0.15 11.6 0.0 5.0 5 1 0 6 6 6 0 AAA domain DUF948 PF06103.11 KPI44885.1 - 0.34 11.2 13.8 1.8 8.9 1.0 4.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4735 PF15882.5 KPI44885.1 - 0.64 9.4 6.8 5.3 6.4 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) ERM PF00769.19 KPI44885.1 - 0.86 9.4 82.3 0.045 13.6 2.7 4.5 4 0 0 4 4 4 0 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.12 KPI44885.1 - 8 6.5 10.4 11 6.0 0.0 4.3 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus GPI-anchored PF10342.9 KPI44887.1 - 2.3e-16 60.3 0.1 2.3e-16 60.3 0.1 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4684 PF15736.5 KPI44887.1 - 0.041 12.6 10.0 0.05 12.3 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) DJ-1_PfpI PF01965.24 KPI44888.1 - 1.2e-05 25.2 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Ribonuclease PF00545.20 KPI44890.1 - 0.083 13.6 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 ribonuclease DEC-1_N PF04625.13 KPI44890.1 - 1.4 7.9 11.8 1.7 7.6 11.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Mito_fiss_reg PF05308.11 KPI44890.1 - 2.5 8.1 7.9 3.3 7.7 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KPI44890.1 - 7 6.0 12.6 9.9 5.5 12.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal COPIIcoated_ERV PF07970.12 KPI44891.1 - 7e-85 284.4 0.0 1.1e-84 283.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KPI44891.1 - 5.4e-30 103.6 0.0 2.2e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MFS_1 PF07690.16 KPI44892.1 - 1.1e-07 31.1 39.4 1.1e-07 31.1 39.4 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI44892.1 - 0.00013 21.0 7.2 0.00023 20.2 2.9 2.3 2 1 0 2 2 2 2 MFS_1 like family Trp_oprn_chp PF09534.10 KPI44892.1 - 1.4 8.6 6.8 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) bZIP_1 PF00170.21 KPI44894.1 - 0.00052 20.0 6.1 0.0012 18.9 6.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor RGS12_usC PF16612.5 KPI44894.1 - 0.046 14.2 0.9 0.046 14.2 0.9 2.0 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 bZIP_2 PF07716.15 KPI44894.1 - 0.36 11.0 13.6 0.24 11.5 5.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF1501 PF07394.12 KPI44894.1 - 0.52 9.3 3.8 0.9 8.5 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Aminopep PF10023.9 KPI44894.1 - 1 8.7 4.5 1.4 8.2 4.5 1.1 1 0 0 1 1 1 0 Putative aminopeptidase TEX13 PF15186.6 KPI44894.1 - 8 6.1 8.8 12 5.6 8.8 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family PSP1 PF04468.12 KPI44895.1 - 3.6e-27 94.5 2.5 6.7e-27 93.6 2.5 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4391 PF14335.6 KPI44895.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF846 PF05832.12 KPI44896.1 - 4.6e-46 156.3 10.0 5.6e-46 156.0 10.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 KPI44896.1 - 0.37 11.6 3.7 0.18 12.6 1.4 1.6 2 0 0 2 2 2 0 Transmembrane family 220, helix MFMR_assoc PF16596.5 KPI44897.1 - 0.19 12.2 10.3 1.2 9.6 0.4 3.5 3 0 0 3 3 3 0 Disordered region downstream of MFMR FMN_dh PF01070.18 KPI44898.1 - 1.6e-120 402.3 0.0 2.7e-120 401.6 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ABC_membrane PF00664.23 KPI44898.1 - 4.3e-82 275.8 31.4 9.8e-43 146.8 12.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI44898.1 - 3e-62 209.2 0.0 2e-33 115.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI44898.1 - 2.8e-11 43.3 1.6 0.00012 21.6 0.8 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KPI44898.1 - 1e-09 38.8 0.3 0.00021 21.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KPI44898.1 - 8.5e-09 36.0 0.6 0.0022 18.4 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KPI44898.1 - 2.3e-08 33.3 0.4 0.0034 16.3 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KPI44898.1 - 4.5e-08 33.2 0.0 0.0066 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase IMPDH PF00478.25 KPI44898.1 - 5.7e-07 28.9 0.1 8.4e-05 21.7 0.1 2.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain AAA_30 PF13604.6 KPI44898.1 - 2.6e-06 27.3 0.2 0.0082 15.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KPI44898.1 - 3.6e-06 26.6 0.9 0.052 13.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KPI44898.1 - 9.7e-06 25.3 0.0 0.072 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Glu_synthase PF01645.17 KPI44898.1 - 7.8e-05 22.0 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase AAA_21 PF13304.6 KPI44898.1 - 8.5e-05 22.5 0.0 1.7 8.4 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KPI44898.1 - 0.00011 22.4 0.8 1 9.6 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KPI44898.1 - 0.0002 21.4 0.1 1.1 9.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KPI44898.1 - 0.00029 21.3 1.6 1.3 9.5 0.0 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KPI44898.1 - 0.00064 19.5 0.0 0.65 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KPI44898.1 - 0.0029 17.6 0.1 0.83 9.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KPI44898.1 - 0.0041 17.4 1.1 2 8.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KPI44898.1 - 0.0045 17.1 0.1 5.8 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KPI44898.1 - 0.0047 17.0 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KPI44898.1 - 0.0067 16.0 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KPI44898.1 - 0.0069 16.9 0.1 8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KPI44898.1 - 0.0079 15.5 0.0 3.3 6.9 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin His_biosynth PF00977.21 KPI44898.1 - 0.012 15.1 0.0 0.056 12.9 0.0 2.1 1 1 0 1 1 1 0 Histidine biosynthesis protein RNA_helicase PF00910.22 KPI44898.1 - 0.015 15.7 0.1 10 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KPI44898.1 - 0.025 14.4 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KPI44898.1 - 0.063 12.9 0.1 0.59 9.7 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KPI44898.1 - 0.096 13.2 0.6 17 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KPI44898.1 - 0.12 12.0 0.2 1.5 8.4 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KPI44898.1 - 0.12 11.5 0.0 7.6 5.6 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.12 KPI44898.1 - 0.16 11.9 0.3 7.4 6.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 KPI44898.1 - 0.16 11.1 0.0 11 5.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Drf_GBD PF06371.13 KPI44899.1 - 0.0046 16.6 1.0 0.029 13.9 0.3 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF3824 PF12868.7 KPI44901.1 - 6.1e-09 36.7 51.8 6.1e-09 36.7 51.8 9.9 2 2 5 9 9 9 4 Domain of unknwon function (DUF3824) Aldo_ket_red PF00248.21 KPI44902.1 - 1.3e-36 126.3 0.0 6.4e-30 104.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family NDUFA12 PF05071.16 KPI44903.1 - 2.7e-13 50.5 4.9 4.4e-13 49.9 4.9 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ABM PF03992.16 KPI44904.1 - 0.02 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Gamma_PGA_hydro PF05908.11 KPI44904.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase Myb_DNA-binding PF00249.31 KPI44905.1 - 7e-05 22.9 1.2 0.00012 22.2 1.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain 2-Hacid_dh_C PF02826.19 KPI44906.1 - 8.2e-52 175.1 0.0 1.1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KPI44906.1 - 1.6e-19 69.9 0.0 2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KPI44906.1 - 0.00044 20.5 0.1 0.00073 19.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 KPI44906.1 - 0.0014 19.5 0.0 0.0031 18.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KPI44906.1 - 0.083 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CCT PF06203.14 KPI44906.1 - 0.083 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 CCT motif PRKCSH PF07915.13 KPI44907.1 - 6.7e-18 65.5 0.2 2e-17 63.9 0.2 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KPI44907.1 - 0.03 14.0 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DRTGG PF07085.12 KPI44907.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 DRTGG domain FMN_bind_2 PF04299.12 KPI44908.1 - 1.2e-50 171.5 0.1 1.8e-50 171.0 0.1 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain SNF2_N PF00176.23 KPI44909.1 - 1.4e-51 175.3 0.1 2e-51 174.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KPI44909.1 - 2.7e-11 43.8 0.0 1e-10 41.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI44909.1 - 0.00034 20.4 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicty_REP PF05086.12 KPI44909.1 - 0.079 10.9 5.4 0.35 8.8 0.0 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein HHH_3 PF12836.7 KPI44909.1 - 0.099 12.9 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif ADH_N PF08240.12 KPI44910.1 - 1.6e-21 76.2 4.7 3.4e-21 75.2 4.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI44910.1 - 2.2e-16 60.0 0.1 7e-16 58.4 0.1 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KPI44910.1 - 1.1e-05 24.9 0.2 2.4e-05 23.8 0.2 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KPI44910.1 - 0.00017 21.0 0.4 0.00027 20.3 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KPI44910.1 - 0.012 15.7 0.1 0.025 14.8 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KPI44910.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KPI44910.1 - 0.17 11.8 0.3 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_E PF05680.12 KPI44911.1 - 4.2e-20 71.9 0.0 4.2e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain 4HBT_2 PF13279.6 KPI44912.1 - 2.4e-10 41.0 0.0 3.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily BRI3BP PF14965.6 KPI44912.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 MMR_HSR1 PF01926.23 KPI44913.1 - 2.3e-08 34.1 0.3 1.3e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI44913.1 - 0.004 17.1 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KPI44913.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KPI44913.1 - 0.021 14.6 0.0 0.021 14.6 0.0 2.4 3 2 1 4 4 4 0 AAA domain AAA_22 PF13401.6 KPI44913.1 - 0.028 14.7 0.1 0.081 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI44913.1 - 0.034 14.7 2.6 0.05 14.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain MCM PF00493.23 KPI44913.1 - 0.037 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 KPI44913.1 - 0.052 13.9 0.0 0.052 13.9 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 KPI44913.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain FeoB_N PF02421.18 KPI44913.1 - 0.061 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 KPI44913.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 KPI44913.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.7 2 2 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.15 KPI44913.1 - 0.31 10.6 6.0 0.41 10.2 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KPI44913.1 - 0.46 9.8 13.7 0.79 9.0 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VPS38 PF17649.1 KPI44913.1 - 2.3 7.0 5.2 3.4 6.4 5.2 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Glyoxalase PF00903.25 KPI44914.1 - 0.024 14.8 0.1 0.21 11.8 0.1 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Toxin_33 PF08121.11 KPI44914.1 - 1.4 8.8 4.0 6.6 6.6 0.5 2.3 2 0 0 2 2 2 0 Waglerin family SpoIIE PF07228.12 KPI44915.1 - 1.8e-12 47.6 0.0 1.7e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KPI44915.1 - 9.6e-09 35.2 0.1 0.0027 17.4 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KPI44915.1 - 3.6e-08 33.3 0.0 9e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Methyltransf_23 PF13489.6 KPI44916.1 - 3.9e-18 65.8 0.0 5.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI44916.1 - 4.3e-13 49.8 0.0 8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI44916.1 - 5.5e-12 46.2 0.0 3.6e-11 43.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI44916.1 - 1.1e-10 42.0 0.0 1.7e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI44916.1 - 7e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KPI44916.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KPI44916.1 - 0.00022 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 KPI44916.1 - 0.00032 20.4 0.0 0.0013 18.4 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 KPI44916.1 - 0.0059 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 KPI44916.1 - 0.062 12.3 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.18 KPI44916.1 - 0.062 12.6 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 KPI44916.1 - 0.07 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.19 KPI44916.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KPI44916.1 - 0.12 12.4 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KPI44916.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 KPI44916.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AA_permease_2 PF13520.6 KPI44917.1 - 1.6e-61 208.4 55.4 2e-61 208.1 55.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI44917.1 - 2.2e-21 76.0 47.4 3e-21 75.6 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease AKAP7_NLS PF10469.9 KPI44919.1 - 1.1e-19 71.2 0.0 4e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KPI44919.1 - 1e-07 32.0 0.7 2.2e-07 30.9 0.0 1.9 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KPI44919.1 - 0.00019 21.6 0.5 0.08 13.1 0.0 3.5 3 0 0 3 3 3 1 LigT like Phosphoesterase DUF5444 PF17519.2 KPI44919.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5444) SSP160 PF06933.11 KPI44919.1 - 0.42 8.8 2.5 0.67 8.1 2.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 OB_NTP_bind PF07717.16 KPI44921.1 - 4.6e-22 78.2 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KPI44921.1 - 4e-19 68.9 0.0 4e-19 68.9 0.0 3.1 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KPI44921.1 - 8.6e-13 48.6 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KPI44921.1 - 8.5e-08 32.2 0.1 2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KPI44921.1 - 2.4e-05 24.7 0.1 5.8e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KPI44921.1 - 2.4e-05 24.6 0.0 8.9e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI44921.1 - 9e-05 22.3 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KPI44921.1 - 0.002 17.3 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KPI44921.1 - 0.036 13.7 0.2 0.097 12.3 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 KPI44921.1 - 0.047 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KPI44921.1 - 0.073 13.6 2.5 1 9.9 0.1 3.7 3 1 1 4 4 3 0 ABC transporter AAA_7 PF12775.7 KPI44921.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KPI44921.1 - 0.13 12.8 0.0 0.13 12.8 0.0 3.5 1 1 1 2 2 1 0 AAA domain dCMP_cyt_deam_1 PF00383.23 KPI44922.1 - 6e-07 29.3 1.4 3e-06 27.0 1.4 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KPI44922.1 - 0.00019 21.6 0.3 0.078 13.2 0.1 2.4 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Frankia_peptide PF14407.6 KPI44922.1 - 0.069 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. LmjF365940-deam PF14421.6 KPI44922.1 - 0.11 12.1 2.7 3.7 7.1 0.2 2.2 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases UPF0261 PF06792.11 KPI44923.1 - 8.5e-41 140.2 0.1 1e-40 140.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PRT_C PF08372.10 KPI44925.1 - 0.00036 20.3 1.4 0.65 9.7 0.1 3.0 2 1 1 3 3 3 2 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 KPI44925.1 - 0.064 12.2 3.5 0.11 11.4 3.5 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Reticulon PF02453.17 KPI44925.1 - 0.085 12.8 4.7 3.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Reticulon DUF3292 PF11696.8 KPI44925.1 - 0.51 8.6 8.2 3.2 6.0 1.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3292) Cupin_2 PF07883.11 KPI44926.1 - 8.5e-12 44.6 0.2 1.5e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KPI44926.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 KPI44926.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Atg14 PF10186.9 KPI44927.1 - 2e-52 178.3 0.0 3.4e-52 177.5 0.0 1.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KPI44927.1 - 0.053 14.0 0.2 0.053 14.0 0.2 1.8 2 0 0 2 2 2 0 Fez1 Filament PF00038.21 KPI44927.1 - 0.11 12.1 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Intermediate filament protein KfrA_N PF11740.8 KPI44927.1 - 3.7 8.3 5.8 1.4 9.6 1.1 2.4 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term CCDC24 PF15669.5 KPI44927.1 - 4.7 7.0 6.4 0.76 9.6 1.5 2.0 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family tRNA-synt_2c PF01411.19 KPI44928.1 - 2.5e-212 706.3 0.0 2.5e-212 706.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KPI44928.1 - 3e-18 65.6 1.5 8.1e-18 64.2 1.5 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KPI44928.1 - 0.00015 22.2 5.0 0.00017 22.0 2.9 2.3 2 0 0 2 2 2 1 DHHA1 domain Ntox30 PF15532.6 KPI44928.1 - 0.028 14.8 0.1 0.08 13.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial toxin 30 TAP_C PF03943.13 KPI44929.1 - 6.9e-10 38.4 0.2 1.7e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 TAP C-terminal domain CTK3_C PF12350.8 KPI44929.1 - 7.4e-10 38.8 3.3 1.4e-09 38.0 3.3 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus LRR_4 PF12799.7 KPI44929.1 - 3.9e-08 33.5 13.3 7.1e-06 26.3 4.1 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI44929.1 - 0.00087 19.0 0.9 0.0022 17.7 0.9 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KPI44929.1 - 0.0013 18.6 2.4 2.7 8.3 0.6 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KPI44929.1 - 0.023 15.2 1.3 12 6.9 0.3 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_9 PF14580.6 KPI44929.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat PAS_9 PF13426.7 KPI44930.1 - 5.5e-15 55.5 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain RGS PF00615.19 KPI44930.1 - 2e-13 50.7 0.1 5.5e-13 49.2 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.25 KPI44930.1 - 1.3e-05 25.2 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KPI44930.1 - 0.0068 16.7 0.0 0.044 14.1 0.0 2.4 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KPI44930.1 - 0.029 14.6 0.0 0.39 11.0 0.0 2.8 3 0 0 3 3 3 0 PAS fold DUF5480 PF17576.2 KPI44930.1 - 0.049 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5480) PMT PF02366.18 KPI44931.1 - 1.8e-85 286.4 15.7 3e-85 285.7 15.7 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KPI44931.1 - 8.9e-68 227.8 6.1 8.9e-68 227.8 6.1 3.3 2 2 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KPI44931.1 - 4.2e-16 59.3 0.3 8.3e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KPI44931.1 - 9.1 6.5 27.0 0.082 13.1 10.8 4.2 5 1 0 5 5 5 0 Dolichyl-phosphate-mannose-protein mannosyltransferase PLA2_B PF01735.18 KPI44932.1 - 3.7e-09 35.5 7.0 4.4e-09 35.3 7.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain BRAP2 PF07576.12 KPI44934.1 - 6.4e-32 109.7 0.0 1.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KPI44934.1 - 5.2e-20 71.5 2.9 1.8e-19 69.8 2.9 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KPI44934.1 - 5.4e-09 36.2 8.8 5.4e-09 36.2 8.8 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KPI44934.1 - 6.6e-07 29.1 9.1 1.7e-06 27.7 9.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI44934.1 - 1e-05 25.2 4.8 1e-05 25.2 4.8 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI44934.1 - 1.9e-05 24.4 7.4 4.6e-05 23.2 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI44934.1 - 5.9e-05 23.0 7.0 0.00026 21.0 7.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KPI44934.1 - 7.6e-05 22.5 5.2 7.6e-05 22.5 5.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI44934.1 - 0.0002 21.2 6.8 0.0002 21.2 6.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KPI44934.1 - 0.00025 21.3 6.7 0.00069 19.9 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI44934.1 - 0.0075 16.3 6.3 0.022 14.8 6.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KPI44934.1 - 0.027 14.3 3.9 0.069 13.0 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.6 KPI44934.1 - 0.16 12.3 5.9 3.2 8.1 0.5 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING_4 PF14570.6 KPI44934.1 - 0.18 11.6 6.1 0.4 10.5 6.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KPI44934.1 - 0.92 9.4 19.8 0.093 12.6 10.6 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 XhlA PF10779.9 KPI44934.1 - 6.1 7.1 11.9 0.37 11.0 1.7 2.8 2 1 0 2 2 2 0 Haemolysin XhlA p450 PF00067.22 KPI44935.1 - 2e-70 237.9 0.0 2.2e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helicase_C PF00271.31 KPI44936.1 - 8.5e-09 35.7 0.0 1.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OrsD PF12013.8 KPI44936.1 - 0.00011 22.7 0.4 0.00032 21.1 0.1 2.1 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KPI44936.1 - 0.00041 20.2 0.3 0.00089 19.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KPI44936.1 - 0.03 14.3 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ADH_N PF08240.12 KPI44937.1 - 1.4e-05 24.9 0.4 0.00016 21.5 0.2 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_L PF01193.24 KPI44938.1 - 6.8e-19 67.1 0.0 1.5e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 KPI44938.1 - 1.6e-15 57.5 0.0 3.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain WD40 PF00400.32 KPI44940.1 - 3.4e-30 103.6 24.7 2.3e-07 31.4 0.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat PRP4 PF08799.11 KPI44940.1 - 4.9e-15 54.8 1.1 1e-14 53.8 1.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KPI44940.1 - 2.5e-11 43.7 0.1 0.025 14.9 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KPI44940.1 - 0.17 11.2 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain DHHC PF01529.20 KPI44941.1 - 4e-31 107.9 5.3 7.7e-31 107.0 5.3 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KPI44941.1 - 0.0076 16.1 0.1 0.26 11.2 0.6 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily DZR PF12773.7 KPI44941.1 - 4.2 7.5 11.2 7.4 6.7 11.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 KPI44942.1 - 1.4e-29 100.9 43.6 5e-05 23.5 0.1 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI44942.1 - 4.2e-19 67.6 44.6 0.0072 17.1 0.6 9.6 10 0 0 10 10 9 8 C2H2-type zinc finger zf_Hakai PF18408.1 KPI44942.1 - 5e-09 35.7 6.8 0.022 14.5 0.1 5.1 5 0 0 5 5 5 3 C2H2 Hakai zinc finger domain zf-H2C2_2 PF13465.6 KPI44942.1 - 4.3e-08 33.2 47.1 3.1e-05 24.2 0.7 9.3 10 0 0 10 10 10 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KPI44942.1 - 8.3e-08 32.3 16.3 8.3 6.8 1.0 7.7 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KPI44942.1 - 2.6e-07 31.2 28.7 0.00065 20.3 0.2 7.8 4 2 4 8 8 8 2 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KPI44942.1 - 6.9e-06 25.8 4.6 3.1 7.8 0.0 4.7 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KPI44942.1 - 4.3e-05 23.7 19.7 0.099 13.0 7.5 4.9 2 2 2 5 5 5 2 C2H2-type zinc ribbon zf-met PF12874.7 KPI44942.1 - 8.3e-05 22.8 5.0 11 6.6 0.0 6.1 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KPI44942.1 - 0.0014 18.4 11.0 1.2 8.9 0.1 4.8 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KPI44942.1 - 0.0036 18.0 19.9 1.8 9.3 3.4 5.2 2 2 3 5 5 5 3 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KPI44942.1 - 0.042 13.7 3.4 0.15 11.8 0.0 2.8 3 0 0 3 3 3 0 GAGA factor Ogr_Delta PF04606.12 KPI44942.1 - 0.16 11.9 0.0 0.16 11.9 0.0 4.2 3 1 1 4 4 3 0 Ogr/Delta-like zinc finger Anillin_N PF16018.5 KPI44942.1 - 0.41 11.3 3.3 2.8 8.6 0.4 2.6 2 0 0 2 2 2 0 Anillin N-terminus HNH PF01844.23 KPI44942.1 - 0.51 10.6 5.7 1.9 8.7 0.0 3.8 3 1 1 4 4 4 0 HNH endonuclease zf-C2H2_6 PF13912.6 KPI44942.1 - 4.2 7.5 24.3 1.6 8.8 0.0 7.2 8 0 0 8 8 8 0 C2H2-type zinc finger HSP70 PF00012.20 KPI44943.1 - 3.5e-181 603.5 7.7 3.8e-181 603.3 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KPI44943.1 - 2.6e-15 56.1 0.1 4.1e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 KPI44943.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ATP-synt_DE PF00401.20 KPI44943.1 - 0.28 11.5 4.2 1 9.6 0.9 2.8 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PIP5K PF01504.18 KPI44944.1 - 6.7e-97 324.0 0.0 6.7e-97 324.0 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase SGL PF08450.12 KPI44945.1 - 1.9e-42 145.6 0.0 2.5e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPI44945.1 - 2.3e-07 30.5 0.0 0.85 9.8 0.0 5.0 5 0 0 5 5 5 2 NHL repeat Str_synth PF03088.16 KPI44945.1 - 5.6e-07 29.6 0.1 0.0018 18.4 0.0 3.6 2 2 1 3 3 3 2 Strictosidine synthase Arylesterase PF01731.20 KPI44945.1 - 1.5e-05 25.1 0.0 0.002 18.3 0.0 3.7 3 1 1 4 4 4 1 Arylesterase Lactonase PF10282.9 KPI44945.1 - 0.0017 17.7 0.0 0.0036 16.6 0.0 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Acyl-CoA_dh_1 PF00441.24 KPI44946.1 - 2.5e-24 86.2 0.1 4.2e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KPI44946.1 - 1.9e-22 80.1 0.0 3.1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KPI44946.1 - 4e-17 62.2 0.0 6.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KPI44946.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MMS19_C PF12460.8 KPI44947.1 - 4.2e-83 279.8 9.5 5.4e-83 279.5 9.5 1.1 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 KPI44947.1 - 1.4e-05 25.5 5.1 0.077 13.5 0.1 3.8 3 0 0 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.6 KPI44947.1 - 2e-05 24.9 2.9 0.52 10.7 0.1 3.5 3 0 0 3 3 3 3 HEAT repeats HEAT PF02985.22 KPI44947.1 - 0.016 15.4 4.3 18 5.9 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 KPI44947.1 - 0.12 12.5 4.3 1.2 9.3 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 KPI44948.1 - 1.3e-57 195.1 0.1 2.8e-51 174.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44948.1 - 1.9e-36 125.7 0.0 1.5e-34 119.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KPI44948.1 - 1.1e-08 34.8 0.0 4.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KPI44948.1 - 0.0078 15.0 0.1 0.023 13.5 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KPI44948.1 - 0.056 13.4 0.0 0.056 13.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Chitin_synth_2 PF03142.15 KPI44950.1 - 7.4e-264 876.2 4.0 4.4e-263 873.7 4.0 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KPI44950.1 - 8.5e-10 38.9 0.1 9.3e-08 32.2 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KPI44950.1 - 4.9e-07 29.8 11.2 5.2e-06 26.5 11.2 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KPI44950.1 - 0.011 15.2 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KPI44950.1 - 0.056 13.2 0.0 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF1829 PF08862.10 KPI44950.1 - 0.081 13.4 0.0 0.28 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF1829 UQ_con PF00179.26 KPI44951.1 - 6e-24 84.3 0.0 8.4e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 KPI44952.1 - 6.2e-59 199.5 0.0 6.1e-38 130.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI44952.1 - 6.6e-27 94.4 0.0 3.8e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KPI44952.1 - 3.2e-13 49.8 0.1 7.6e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KPI44952.1 - 3.6e-08 33.1 0.0 2.9e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KPI44952.1 - 2.9e-05 24.1 0.0 0.0031 17.5 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KPI44952.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPI44952.1 - 0.054 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KPI44952.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ApoA-II PF04711.13 KPI44952.1 - 0.18 12.0 0.3 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) Spermine_synth PF01564.17 KPI44954.1 - 0.088 12.2 0.6 0.89 8.9 0.1 2.0 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Fasciclin PF02469.22 KPI44956.1 - 0.001 19.3 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain p450 PF00067.22 KPI44958.1 - 4.4e-47 160.9 0.0 5.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 KPI44959.1 - 1.4e-11 44.9 5.1 5e-09 36.7 0.4 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sirohm_synth_C PF14823.6 KPI44959.1 - 6.8 6.4 6.2 0.86 9.3 0.1 2.6 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal tRNA-synt_1 PF00133.22 KPI44960.1 - 2.9e-218 726.0 4.1 3.7e-217 722.3 4.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KPI44960.1 - 7.7e-36 123.3 0.0 7.7e-36 123.3 0.0 2.9 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KPI44960.1 - 7e-14 51.4 3.1 3.6e-06 26.0 0.1 4.9 2 2 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KPI44960.1 - 6.6e-08 32.3 9.0 2.6e-07 30.4 0.0 3.8 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KPI44960.1 - 0.0053 16.2 0.0 0.13 11.6 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 KPI44960.1 - 0.011 16.0 7.2 0.011 16.0 7.2 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PepSY PF03413.19 KPI44960.1 - 0.076 13.6 2.0 0.15 12.7 0.1 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Mitoc_mL59 PF18126.1 KPI44960.1 - 0.083 13.2 6.6 0.48 10.7 0.2 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 Ribosomal_L37 PF08561.10 KPI44961.1 - 7e-38 129.8 0.8 9.1e-38 129.5 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Acyl_transf_3 PF01757.22 KPI44962.1 - 8.1e-23 81.0 20.1 1e-22 80.7 20.1 1.1 1 0 0 1 1 1 1 Acyltransferase family TMEM220 PF15071.6 KPI44962.1 - 0.11 13.2 2.1 0.26 12.0 0.5 2.5 2 0 0 2 2 2 0 Transmembrane family 220, helix ASFV_J13L PF05568.11 KPI44963.1 - 0.025 14.4 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein zf-GRF PF06839.12 KPI44964.1 - 1.9e-08 34.3 7.5 3.2e-08 33.6 7.5 1.4 1 0 0 1 1 1 1 GRF zinc finger bZIP_1 PF00170.21 KPI44964.1 - 0.061 13.4 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor PKcGMP_CC PF16808.5 KPI44964.1 - 0.094 12.6 1.2 0.21 11.5 1.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1192 PF06698.11 KPI44964.1 - 0.13 12.3 1.6 1.8 8.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) RNA_pol_Rpb6 PF01192.22 KPI44965.1 - 2.8e-16 59.2 0.1 4.8e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 KPI44965.1 - 0.0092 16.0 0.3 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4549 PF15082.6 KPI44965.1 - 0.17 11.7 0.3 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) Nop14 PF04147.12 KPI44965.1 - 0.17 10.0 4.0 0.17 10.1 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family CBM_4_9 PF02018.17 KPI44966.1 - 0.00044 20.5 0.0 0.00082 19.7 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain PAN_4 PF14295.6 KPI44966.1 - 0.0025 17.7 2.1 0.0062 16.4 2.1 1.7 1 0 0 1 1 1 1 PAN domain Fungal_trans PF04082.18 KPI44966.1 - 0.076 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain PLA2_B PF01735.18 KPI44967.1 - 3.9e-69 233.3 0.0 5.1e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Abhydrolase_1 PF00561.20 KPI44968.1 - 1.3e-11 44.6 0.0 1.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KPI44968.1 - 2.3e-10 41.4 0.9 2.8e-10 41.2 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KPI44968.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Ndr PF03096.14 KPI44968.1 - 0.069 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family Phosducin PF02114.16 KPI44969.1 - 9.4e-10 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin RNA_pol_Rpb2_2 PF04561.14 KPI44970.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 TMEM51 PF15345.6 KPI44970.1 - 0.012 15.5 0.3 0.018 14.9 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Phage_Gp23 PF10669.9 KPI44970.1 - 0.017 15.5 1.3 0.026 14.8 1.3 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NEMP PF10225.9 KPI44970.1 - 0.022 14.4 0.2 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 NEMP family Serinc PF03348.15 KPI44970.1 - 0.055 12.4 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF5531 PF17671.1 KPI44970.1 - 0.11 12.4 0.8 0.2 11.5 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) DUF1682 PF07946.14 KPI44970.1 - 3.2 6.9 6.9 4.5 6.4 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MscS_TM PF12794.7 KPI44970.1 - 5.6 5.7 5.2 2.2 7.0 1.3 1.8 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 RAP1 PF07218.11 KPI44970.1 - 8.2 4.6 5.6 14 3.8 5.6 1.3 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.16 KPI44971.1 - 1.2e-21 77.1 48.9 2.4e-14 53.0 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily G-gamma PF00631.22 KPI44972.1 - 9.6e-22 76.8 0.1 1.1e-21 76.6 0.1 1.1 1 0 0 1 1 1 1 GGL domain OPA3 PF07047.12 KPI44973.1 - 1.9e-47 160.2 1.8 1.9e-47 160.2 1.8 1.5 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) MSA-2c PF12238.8 KPI44973.1 - 0.001 19.1 1.2 0.0023 18.0 0.1 1.9 2 0 0 2 2 2 1 Merozoite surface antigen 2c BatD PF13584.6 KPI44973.1 - 0.017 14.0 0.8 0.025 13.4 0.8 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF3844 PF12955.7 KPI44974.1 - 7e-32 109.7 3.8 1.1e-31 109.1 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Lipase_3 PF01764.25 KPI44975.1 - 3e-13 49.9 0.1 2.1e-09 37.4 0.2 2.4 2 0 0 2 2 2 2 Lipase (class 3) Hydrolase_4 PF12146.8 KPI44975.1 - 0.0032 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI44975.1 - 0.0037 17.9 3.4 0.0067 17.1 3.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family GHMP_kinases_C PF08544.13 KPI44975.1 - 0.051 13.9 0.2 0.051 13.9 0.2 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal Esterase PF00756.20 KPI44975.1 - 0.18 11.5 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KPI44975.1 - 0.19 11.4 0.1 1 9.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KPI44975.1 - 0.2 11.6 0.1 0.54 10.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Exo_endo_phos PF03372.23 KPI44976.1 - 4.8e-05 23.0 0.0 9.1e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.26 KPI44977.1 - 3.5e-52 175.8 0.0 3.9e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KPI44977.1 - 0.0085 15.8 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KPI44977.1 - 0.043 14.1 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KPI44977.1 - 0.046 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF2304 PF10066.9 KPI44978.1 - 0.036 14.3 0.8 0.036 14.3 0.8 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Polysacc_synt_C PF14667.6 KPI44978.1 - 1.5 8.9 12.2 3.5 7.7 12.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Glyco_transf_25 PF01755.17 KPI44979.1 - 2.6e-13 50.3 0.2 6.8e-12 45.7 0.2 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4337 PF14235.6 KPI44979.1 - 7.3 6.7 9.2 13 5.8 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DivIC PF04977.15 KPI44979.1 - 8.1 6.3 9.5 7.5 6.4 7.8 1.7 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 KPI44980.1 - 3.1e-08 33.6 7.4 7.1e-08 32.4 7.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KPI44980.1 - 4.1e-08 33.4 2.5 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Transcription factor PAP1 TMF_TATA_bd PF12325.8 KPI44980.1 - 0.0017 18.5 3.0 0.0032 17.7 3.0 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.17 KPI44980.1 - 0.0052 17.3 8.1 0.0052 17.3 8.1 1.5 2 0 0 2 2 1 1 bZIP Maf transcription factor SHE3 PF17078.5 KPI44980.1 - 0.0099 15.6 4.0 0.015 15.0 4.0 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GIT_CC PF16559.5 KPI44980.1 - 0.013 15.4 0.2 0.029 14.2 0.2 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 KPI44980.1 - 0.027 14.6 13.1 0.035 14.2 11.7 1.8 1 1 1 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 KPI44980.1 - 0.038 14.6 0.3 0.099 13.3 0.0 1.9 2 0 0 2 2 1 0 SlyX V_ATPase_I PF01496.19 KPI44980.1 - 0.039 11.9 1.0 0.053 11.4 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 KPI44980.1 - 0.11 12.9 2.6 0.18 12.2 2.6 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HALZ PF02183.18 KPI44980.1 - 0.14 12.4 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper PSI_PsaF PF02507.15 KPI44980.1 - 0.26 11.1 0.3 0.42 10.4 0.3 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Amidohydro_1 PF01979.20 KPI44982.1 - 2e-25 89.8 0.2 3.9e-25 88.9 0.2 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI44982.1 - 8.8e-13 48.5 0.0 6.5e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Mito_carr PF00153.27 KPI44983.1 - 2.8e-70 232.3 0.1 1.2e-23 82.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KPI44983.1 - 7.5e-13 48.7 4.8 3.7e-06 27.3 0.7 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KPI44983.1 - 3.8e-11 42.0 5.5 2.5e-06 27.0 0.1 5.6 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 KPI44983.1 - 4.6e-10 38.3 3.7 6.2e-06 25.4 0.0 5.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KPI44983.1 - 4.3e-06 26.5 0.7 5.2 7.0 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KPI44983.1 - 0.00012 21.4 1.4 0.064 12.8 0.0 4.4 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 KPI44983.1 - 0.0055 17.0 0.1 7.6 6.9 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain zf-RING_2 PF13639.6 KPI44984.1 - 6.8e-07 29.5 9.8 1.3e-06 28.7 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KPI44984.1 - 6.2e-06 25.9 4.6 1.3e-05 24.8 4.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KPI44984.1 - 1e-05 25.0 9.1 2.1e-05 24.0 9.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KPI44984.1 - 0.00064 19.6 5.5 0.0011 18.9 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPI44984.1 - 0.0014 18.4 8.1 0.0029 17.4 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI44984.1 - 0.0078 16.1 5.1 0.013 15.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI44984.1 - 0.013 15.3 7.5 0.025 14.5 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI44984.1 - 0.022 14.8 7.1 0.045 13.8 7.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.6 KPI44984.1 - 0.045 13.7 8.5 0.18 11.8 8.6 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 KPI44984.1 - 3.4 8.1 8.6 6.3 7.2 8.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KPI44984.1 - 6.3 7.2 11.3 16 5.9 11.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF4956 PF16316.5 KPI44985.1 - 0.0025 17.5 0.2 0.0037 17.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4956) SH3_1 PF00018.28 KPI44986.1 - 3.2e-34 116.3 9.1 4.8e-11 42.1 0.8 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KPI44986.1 - 6.9e-34 115.5 0.1 1.4e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KPI44986.1 - 2e-28 98.0 6.1 6.6e-10 38.7 0.2 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KPI44986.1 - 3.4e-18 65.1 0.0 3.2e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.11 KPI44986.1 - 1.6e-08 34.8 48.7 1.6e-08 34.8 48.7 6.3 2 1 3 5 5 5 3 Domain of unknown function (DUF1720) SH3_10 PF17902.1 KPI44986.1 - 0.0018 18.3 0.3 3.3 7.8 0.1 3.2 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 KPI44986.1 - 0.0072 16.6 3.0 0.74 10.1 0.4 3.5 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_4 PF18017.1 KPI44986.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PA_decarbox PF05870.11 KPI44987.1 - 4.4e-07 29.7 0.1 5.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MMR_HSR1 PF01926.23 KPI44988.1 - 9.1e-05 22.5 0.0 0.00027 21.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KPI44988.1 - 0.0047 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KPI44988.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KPI44988.1 - 0.047 14.2 1.6 0.42 11.1 1.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KPI44988.1 - 0.079 12.7 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain FlxA PF14282.6 KPI44988.1 - 0.082 12.9 2.0 0.16 11.9 2.0 1.5 1 0 0 1 1 1 0 FlxA-like protein ABC_tran PF00005.27 KPI44988.1 - 0.084 13.4 0.2 1.4 9.4 0.0 2.5 3 0 0 3 3 3 0 ABC transporter DUF4047 PF13256.6 KPI44988.1 - 0.2 11.8 2.1 0.33 11.2 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) AAA_18 PF13238.6 KPI44988.1 - 0.26 11.8 3.1 12 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sugar_tr PF00083.24 KPI44989.1 - 1.6e-42 146.0 14.2 9.9e-27 93.9 4.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI44989.1 - 9.2e-25 87.3 28.7 3.6e-22 78.8 9.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TBCA PF02970.16 KPI44990.1 - 7.9e-23 80.6 10.7 1e-22 80.2 10.7 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Ribosomal_L17 PF01196.19 KPI44990.1 - 0.064 14.2 1.2 0.67 10.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L17 DHR10 PF18595.1 KPI44990.1 - 0.16 12.1 12.0 0.25 11.4 12.0 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Med9 PF07544.13 KPI44990.1 - 0.33 11.1 11.5 0.053 13.6 5.8 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2570 PF10828.8 KPI44990.1 - 0.61 9.9 5.4 1.4 8.7 5.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4407 PF14362.6 KPI44990.1 - 1.9 7.8 8.9 2.2 7.5 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KPI44990.1 - 2.4 7.2 8.3 3.3 6.7 8.3 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 KPI44990.1 - 8.7 7.1 8.3 12 6.6 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4404 PF14357.6 KPI44990.1 - 9.8 6.9 9.1 1.8 9.3 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Abhydrolase_3 PF07859.13 KPI44991.1 - 5.4e-22 78.7 0.0 7.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold ERG4_ERG24 PF01222.17 KPI44993.1 - 5e-82 276.0 14.6 5.7e-82 275.8 14.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Myb_DNA-binding PF00249.31 KPI44994.1 - 1.1e-09 38.4 2.5 5.1e-09 36.2 0.1 2.5 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KPI44994.1 - 2.3e-07 30.9 1.5 6.9e-07 29.4 0.3 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KPI44994.1 - 0.036 14.1 0.0 0.08 13.0 0.0 1.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KPI44994.1 - 0.092 13.1 2.1 3.1 8.2 0.4 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF778 PF05608.12 KPI44994.1 - 0.54 10.6 4.7 1.2 9.5 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Coiled-coil_56 PF09813.9 KPI44995.1 - 2.4e-05 24.3 0.0 2.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 ATP-synt PF00231.19 KPI44996.1 - 5.7e-77 259.2 0.3 8.1e-77 258.7 0.3 1.2 1 0 0 1 1 1 1 ATP synthase TPP_enzyme_N PF02776.18 KPI44997.1 - 1.6e-38 132.0 0.0 4.7e-37 127.2 0.0 2.9 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KPI44997.1 - 4.6e-35 120.3 0.0 8.8e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KPI44997.1 - 2.4e-19 69.7 0.1 9.8e-19 67.6 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Thiolase_N PF00108.23 KPI44998.1 - 2e-93 312.5 1.4 5.1e-93 311.2 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KPI44998.1 - 3e-46 156.1 1.2 7e-46 154.9 1.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KPI44998.1 - 1.1e-05 25.2 0.9 3.1e-05 23.7 0.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KPI44998.1 - 0.0056 16.5 1.2 0.33 10.9 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PHD PF00628.29 KPI44999.1 - 0.16 11.9 2.6 0.59 10.1 2.6 1.9 1 1 0 1 1 1 0 PHD-finger zf-CSL PF05207.13 KPI45000.1 - 2.1e-20 72.2 0.4 3e-20 71.7 0.4 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KPI45000.1 - 8.8e-05 22.5 0.2 0.00017 21.6 0.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 KPI45000.1 - 0.0058 15.2 0.1 0.006 15.2 0.1 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) PAP1 PF08601.10 KPI45000.1 - 0.91 9.2 12.4 1 9.0 12.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 DUF908 PF06012.12 KPI45000.1 - 5.1 6.4 6.4 5.5 6.3 6.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Keratin_2_head PF16208.5 KPI45001.1 - 0.18 12.0 7.0 0.25 11.5 7.0 1.2 1 0 0 1 1 1 0 Keratin type II head Mob1_phocein PF03637.17 KPI45002.1 - 1.2e-72 243.4 0.0 1.7e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family eIF-3_zeta PF05091.12 KPI45003.1 - 5.3e-183 609.7 8.2 1.1e-140 470.1 1.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WD40 PF00400.32 KPI45004.1 - 8.7e-42 140.3 20.8 2.8e-06 27.9 0.2 11.5 11 0 0 11 11 11 8 WD domain, G-beta repeat Utp12 PF04003.12 KPI45004.1 - 6e-18 65.1 0.1 1.2e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KPI45004.1 - 7.5e-17 61.4 2.1 0.029 14.6 0.0 8.6 7 2 1 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI45004.1 - 2.6e-09 36.5 6.9 0.18 10.7 0.0 5.8 3 2 4 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPI45004.1 - 7.7e-07 28.1 2.1 0.43 9.2 0.0 4.4 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PAN_1 PF00024.26 KPI45005.1 - 4.8e-05 23.2 0.8 0.0001 22.2 0.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KPI45005.1 - 8.2e-05 22.4 0.8 0.00018 21.4 0.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KPI45005.1 - 0.0013 18.5 0.5 0.0028 17.4 0.5 1.5 1 0 0 1 1 1 1 PAN-like domain TAFII55_N PF04658.13 KPI45006.1 - 2.9e-43 147.3 0.9 7.2e-43 146.1 0.0 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region Coiled-coil_56 PF09813.9 KPI45006.1 - 0.16 12.0 1.5 0.71 10.0 1.5 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF4094 PF13334.6 KPI45006.1 - 8.3 6.9 6.4 53 4.3 6.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) FSH1 PF03959.13 KPI45007.1 - 4.9e-20 72.1 0.0 3.3e-12 46.5 0.0 2.0 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KPI45007.1 - 0.041 13.7 0.1 0.48 10.2 0.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase UPF0261 PF06792.11 KPI45008.1 - 5.1e-109 364.9 0.2 6.1e-109 364.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Cation_efflux PF01545.21 KPI45009.1 - 9.8e-55 185.4 4.2 1.4e-54 184.8 4.2 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPI45009.1 - 0.0021 18.1 0.0 0.0058 16.7 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SelP_N PF04592.14 KPI45009.1 - 0.019 14.4 1.1 0.019 14.4 1.1 2.7 3 0 0 3 3 3 0 Selenoprotein P, N terminal region Helicase_C PF00271.31 KPI45011.1 - 1.2e-17 64.2 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KPI45011.1 - 0.0085 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase B3_4 PF03483.17 KPI45012.1 - 7.7e-17 61.5 0.0 1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain FAM194 PF14977.6 KPI45012.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 FAM194 protein ADH_zinc_N PF00107.26 KPI45014.1 - 4.2e-08 33.2 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI45014.1 - 1.9e-05 24.5 0.0 0.0001 22.2 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KPI45014.1 - 0.0021 19.1 0.0 0.042 14.9 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KPI45014.1 - 0.021 14.6 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) ADH_N_2 PF16884.5 KPI45014.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Acyl-CoA_dh_1 PF00441.24 KPI45015.1 - 6.6e-30 104.3 0.1 9.2e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KPI45015.1 - 9.2e-23 80.3 0.0 1.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI45015.1 - 3.9e-17 62.9 0.3 1.2e-15 58.1 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Fungal_trans_2 PF11951.8 KPI45016.1 - 0.00073 18.4 0.0 0.0043 15.9 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain PGA2 PF07543.12 KPI45017.1 - 1.5e-13 50.9 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 Ank_2 PF12796.7 KPI45018.1 - 1.5e-09 38.3 0.4 1.4e-08 35.2 0.1 2.6 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KPI45018.1 - 4.4e-08 33.2 0.0 1.7e-06 28.2 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI45018.1 - 9e-08 31.8 0.1 0.0013 19.0 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KPI45018.1 - 5.1e-07 30.1 0.2 5.2e-05 23.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KPI45018.1 - 2.1e-05 24.8 0.6 0.044 14.2 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat YrzK PF17449.2 KPI45019.1 - 0.12 12.7 0.1 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized YrzK-like Hormone_3 PF00159.18 KPI45019.1 - 0.2 11.7 2.1 0.46 10.6 2.1 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide Aminotran_1_2 PF00155.21 KPI45022.1 - 5.4e-15 55.4 0.0 8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KPI45022.1 - 0.0051 15.7 0.0 0.0099 14.7 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 KPI45022.1 - 0.016 14.2 0.2 0.032 13.2 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Frigida PF07899.11 KPI45023.1 - 0.048 12.9 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein SVIP PF15811.5 KPI45023.1 - 1.6 9.2 7.6 2.5 8.6 5.7 2.2 2 1 0 2 2 2 0 Small VCP/p97-interacting protein ATP-synt_ab PF00006.25 KPI45025.1 - 4.2e-74 248.8 0.3 6.7e-74 248.1 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KPI45025.1 - 2e-48 163.9 2.1 3.2e-48 163.2 2.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KPI45025.1 - 5e-16 59.0 3.2 1.3e-15 57.7 3.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.10 KPI45025.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Tex-like protein N-terminal domain betaPIX_CC PF16523.5 KPI45025.1 - 0.15 11.9 0.2 0.36 10.7 0.2 1.5 1 0 0 1 1 1 0 betaPIX coiled coil AAA PF00004.29 KPI45026.1 - 5.8e-50 169.1 0.0 1.2e-43 148.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KPI45026.1 - 3.7e-08 33.0 1.1 0.00011 21.9 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 KPI45026.1 - 0.00011 22.3 0.0 0.009 16.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KPI45026.1 - 0.00022 21.0 0.0 0.00064 19.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KPI45026.1 - 0.0013 19.2 4.1 0.023 15.1 0.0 3.4 3 1 0 4 4 4 1 AAA ATPase domain Parvo_NS1 PF01057.17 KPI45026.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KPI45026.1 - 0.0053 17.1 0.0 0.018 15.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KPI45026.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KPI45026.1 - 0.0074 16.6 0.1 0.056 13.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KPI45026.1 - 0.0075 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KPI45026.1 - 0.026 14.4 0.0 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KPI45026.1 - 0.029 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPI45026.1 - 0.037 14.0 0.0 0.14 12.2 0.0 2.0 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KPI45026.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KPI45026.1 - 0.046 13.3 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KPI45026.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KPI45026.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KPI45026.1 - 0.084 13.1 0.0 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI45026.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KPI45026.1 - 0.46 10.2 3.7 3.9 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain NOA36 PF06524.12 KPI45026.1 - 5.2 6.3 7.4 9 5.5 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein Methyltransf_23 PF13489.6 KPI45027.1 - 1.3e-22 80.3 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI45027.1 - 1.1e-17 64.4 0.0 1.6e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45027.1 - 4.6e-16 59.4 0.0 6.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI45027.1 - 8.8e-16 58.4 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45027.1 - 3.2e-11 43.3 0.0 4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KPI45027.1 - 1.9e-05 24.2 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KPI45027.1 - 5.4e-05 22.8 0.0 0.00036 20.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KPI45027.1 - 0.00091 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KPI45027.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KPI45027.1 - 0.0018 17.7 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KPI45027.1 - 0.07 13.1 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KPI45027.1 - 0.16 11.3 0.0 0.51 9.6 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KPI45027.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PARP_regulatory PF01358.18 KPI45027.1 - 0.3 10.0 0.0 0.42 9.5 0.0 1.1 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit DUF2235 PF09994.9 KPI45028.1 - 4.6e-70 236.2 0.0 6.8e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) LtrA PF06772.11 KPI45029.1 - 8e-12 45.0 20.8 8e-12 45.0 20.8 1.9 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) HP_OMP PF01856.17 KPI45029.1 - 0.044 13.8 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Helicobacter outer membrane protein Herpes_LMP1 PF05297.11 KPI45029.1 - 2.1 7.4 7.2 1.5 7.9 4.7 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Pkinase PF00069.25 KPI45030.1 - 1.8e-40 139.0 0.0 2.5e-39 135.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45030.1 - 1.5e-23 83.4 0.0 2.7e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Vps53_N PF04100.12 KPI45031.1 - 1.9e-87 293.8 0.0 4e-87 292.6 0.0 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 KPI45031.1 - 2.3e-08 32.9 0.0 3.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps54_N PF10475.9 KPI45031.1 - 2.3e-07 30.4 0.2 4.8e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 KPI45031.1 - 1.1e-06 27.8 0.0 1.8e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 RINT-1 / TIP-1 family DUF2451 PF10474.9 KPI45031.1 - 0.00045 20.1 0.0 0.0018 18.1 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Flagellin_C PF00700.21 KPI45031.1 - 0.021 15.1 4.3 0.037 14.4 2.8 2.2 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region COG2 PF06148.11 KPI45031.1 - 0.046 13.8 0.5 0.19 11.9 0.0 2.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KPI45031.1 - 0.06 12.2 1.0 0.12 11.2 1.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KPI45031.1 - 0.11 13.0 1.8 0.17 12.4 0.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KPI45031.1 - 0.12 12.4 1.1 0.36 10.9 1.1 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Beta_elim_lyase PF01212.21 KPI45032.1 - 2.5e-52 178.0 0.0 3e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KPI45032.1 - 0.0016 17.2 0.1 0.002 16.9 0.1 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KPI45032.1 - 0.0032 16.1 0.1 0.0057 15.2 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KPI45032.1 - 0.0067 15.8 0.0 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family FGGY_C PF02782.16 KPI45033.1 - 6.2e-20 71.8 0.0 9.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KPI45033.1 - 1.4e-16 60.9 0.0 1.2e-10 41.4 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF5398 PF17376.2 KPI45033.1 - 0.14 12.8 0.1 0.47 11.1 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Alg6_Alg8 PF03155.15 KPI45035.1 - 5.1e-131 438.0 19.7 1.1e-80 272.0 7.5 2.2 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Metallophos PF00149.28 KPI45036.1 - 3.1e-30 106.2 0.0 3.7e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KPI45036.1 - 4e-23 81.6 0.7 7.2e-23 80.8 0.7 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Fungal_trans PF04082.18 KPI45037.1 - 5.7e-06 25.5 0.0 8.7e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.23 KPI45038.1 - 1.8e-58 198.4 3.2 1.8e-58 198.4 3.2 2.7 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KPI45038.1 - 2.3e-08 34.5 1.8 2.3e-08 34.5 1.8 4.5 3 2 1 4 4 4 1 Xylanase inhibitor N-terminal RPN7 PF10602.9 KPI45039.1 - 3.9e-40 137.4 0.1 7.2e-40 136.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KPI45039.1 - 4.4e-12 46.4 0.5 1.8e-11 44.5 0.2 2.2 2 1 0 2 2 2 1 PCI domain EI24 PF07264.11 KPI45040.1 - 0.002 18.4 3.1 0.77 10.0 1.4 2.5 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF4271 PF14093.6 KPI45040.1 - 0.0036 17.2 0.8 0.0036 17.2 0.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4271) ER_lumen_recept PF00810.18 KPI45040.1 - 0.057 14.2 2.9 0.13 13.1 2.9 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor MFS_1 PF07690.16 KPI45040.1 - 1.5 7.7 10.4 0.058 12.3 4.2 1.8 2 1 0 2 2 2 0 Major Facilitator Superfamily Methyltransf_16 PF10294.9 KPI45041.1 - 0.00054 19.7 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase CorA PF01544.18 KPI45042.1 - 2.2e-11 43.6 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pox_P35 PF03213.14 KPI45042.1 - 0.53 9.5 2.3 1 8.5 2.3 1.6 1 1 0 1 1 1 0 Poxvirus P35 protein FAD_binding_4 PF01565.23 KPI45043.1 - 2.4e-20 72.7 0.2 4.1e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI45043.1 - 0.0013 18.8 0.1 0.0032 17.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 KPI45043.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase E1-E2_ATPase PF00122.20 KPI45046.1 - 7e-35 120.2 4.3 2.8e-34 118.2 0.1 3.3 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KPI45046.1 - 2.2e-16 60.8 0.1 5.4e-16 59.5 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI45046.1 - 9.2e-11 41.3 0.0 2.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPI45046.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPI45046.1 - 0.003 17.4 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sortilin-Vps10 PF15902.5 KPI45047.1 - 8.1e-287 951.0 9.6 3.4e-148 494.1 1.3 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KPI45047.1 - 9.9e-83 276.6 11.7 2.9e-47 161.2 3.8 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KPI45047.1 - 1.1e-09 36.8 40.6 0.67 10.2 0.5 11.8 11 0 0 11 11 11 7 BNR/Asp-box repeat Fn3_assoc PF13287.6 KPI45047.1 - 0.14 12.4 0.4 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Fn3 associated CBS PF00571.28 KPI45049.1 - 3e-07 30.8 0.1 0.071 13.6 0.1 3.1 2 1 0 2 2 2 2 CBS domain adh_short_C2 PF13561.6 KPI45050.1 - 2.2e-56 191.0 0.3 2.9e-56 190.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI45050.1 - 1.2e-46 158.7 2.7 1.4e-46 158.4 2.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI45050.1 - 4.6e-07 29.9 1.3 1.3e-06 28.4 1.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI45050.1 - 0.00056 19.4 0.3 0.00077 19.0 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 KPI45050.1 - 0.024 15.3 0.3 0.062 14.0 0.3 1.7 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 KPI45050.1 - 0.036 14.3 0.2 0.059 13.6 0.2 1.5 1 1 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 KPI45050.1 - 0.16 11.1 1.4 0.52 9.4 0.1 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Sel1 PF08238.12 KPI45051.1 - 1.8e-36 123.7 22.7 1.2e-05 25.8 0.1 7.8 8 0 0 8 8 8 7 Sel1 repeat ATP-synt_DE_N PF02823.16 KPI45053.1 - 4e-17 61.9 0.0 6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain OMPdecase PF00215.24 KPI45054.1 - 3.1e-72 242.8 0.3 3.6e-72 242.6 0.3 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family POLO_box PF00659.18 KPI45055.1 - 0.00024 21.3 0.1 0.00047 20.3 0.1 1.6 1 1 0 1 1 1 1 POLO box duplicated region MFS_1 PF07690.16 KPI45056.1 - 5.9e-32 111.0 40.0 1.7e-31 109.5 40.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI45056.1 - 3.2e-08 32.9 22.9 6.4e-07 28.6 11.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KPI45056.1 - 3.3e-05 22.5 18.8 5.3e-05 21.9 18.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KPI45058.1 - 1.6e-21 76.6 0.1 2.5e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 KPI45059.1 - 0.00022 21.4 0.0 0.0014 18.8 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF3597 PF12200.8 KPI45060.1 - 1.8 9.1 6.2 0.24 11.9 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) RGS PF00615.19 KPI45061.1 - 1.1e-05 25.6 0.1 0.046 14.0 0.0 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain MAP65_ASE1 PF03999.12 KPI45061.1 - 0.099 11.3 0.9 0.14 10.8 0.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_L15e PF00827.17 KPI45062.1 - 5.8e-90 300.2 11.6 7.1e-90 299.9 11.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 CH PF00307.31 KPI45063.1 - 6.4e-14 52.1 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Lactococcin_972 PF09683.10 KPI45065.1 - 1.7 9.2 5.5 0.5 11.0 1.1 2.2 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) Ribonuc_L-PSP PF01042.21 KPI45066.1 - 8.2e-31 106.5 0.0 1.1e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Exo_endo_phos PF03372.23 KPI45067.1 - 1.2e-13 51.1 0.1 1.9e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KPI45067.1 - 2.2e-09 37.4 4.2 1.8e-05 25.0 0.1 2.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI45067.1 - 5.9e-09 35.6 7.3 4.4e-07 29.6 0.4 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KPI45067.1 - 0.012 16.1 0.2 8.7 7.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KPI45067.1 - 2.3 8.5 5.7 11 6.4 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Fungal_trans_2 PF11951.8 KPI45068.1 - 2.1e-50 171.7 0.2 3.1e-50 171.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI45068.1 - 5e-06 26.5 11.8 8.6e-06 25.8 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MS_channel PF00924.18 KPI45069.1 - 4.6e-25 88.4 1.5 7.4e-25 87.7 1.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KPI45069.1 - 0.0001 21.6 0.0 0.00025 20.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KPI45069.1 - 0.0013 18.2 0.1 0.003 17.0 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KPI45069.1 - 0.0019 18.0 0.0 0.0073 16.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KPI45069.1 - 0.015 15.7 0.3 0.045 14.2 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair DUF1056 PF06341.11 KPI45069.1 - 0.056 13.8 1.7 0.22 11.9 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Scramblase PF03803.15 KPI45069.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Scramblase Sugar_tr PF00083.24 KPI45071.1 - 1.1e-54 186.0 19.2 1.3e-54 185.8 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45071.1 - 7e-23 81.1 46.3 1.7e-22 79.8 30.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPI45071.1 - 8.7e-07 27.8 6.7 8.7e-07 27.8 6.7 4.3 4 1 1 5 5 5 2 MFS/sugar transport protein DUF872 PF05915.12 KPI45071.1 - 0.00026 21.2 0.8 0.001 19.2 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) MFS_1_like PF12832.7 KPI45071.1 - 0.0015 17.5 18.1 0.16 10.7 2.6 3.0 1 1 1 2 2 2 2 MFS_1 like family YIEGIA PF14045.6 KPI45071.1 - 0.033 13.0 0.4 0.079 11.8 0.4 1.6 1 0 0 1 1 1 0 YIEGIA protein DUF3087 PF11286.8 KPI45071.1 - 0.33 10.4 0.7 1.1 8.7 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) NEMP PF10225.9 KPI45071.1 - 0.46 10.1 10.2 1.3 8.6 10.2 1.8 1 0 0 1 1 1 0 NEMP family NIR_SIR PF01077.22 KPI45075.1 - 8.3e-18 64.4 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.14 KPI45075.1 - 8.7e-17 61.3 0.1 1.4e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KPI45075.1 - 7.4e-13 48.6 6.7 2.1e-09 37.6 6.1 2.5 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KPI45075.1 - 1.1e-10 41.3 0.4 7.7e-10 38.6 0.0 2.5 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KPI45075.1 - 6.8e-07 29.0 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.6 KPI45075.1 - 7.5e-07 29.0 0.0 1.5e-05 24.9 0.0 3.0 3 1 0 3 3 3 1 Rieske-like [2Fe-2S] domain Rubredoxin_C PF18267.1 KPI45075.1 - 1.9e-05 24.5 0.1 0.097 12.6 0.0 3.3 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Pex19 PF04614.12 KPI45075.1 - 0.021 14.6 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Pex19 protein family PHD PF00628.29 KPI45076.1 - 0.57 10.1 6.2 1.2 9.0 6.2 1.6 1 0 0 1 1 1 0 PHD-finger ORC_WH_C PF18137.1 KPI45077.1 - 2e-28 99.2 0.0 3.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KPI45077.1 - 6e-13 48.6 3.5 9.1e-10 38.1 2.2 2.5 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus ApoO PF09769.9 KPI45077.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein O Amino_oxidase PF01593.24 KPI45078.1 - 6.5e-45 154.3 0.2 7.8e-45 154.0 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI45078.1 - 3.5e-11 43.2 0.4 1.6e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KPI45078.1 - 1.5e-06 28.1 0.3 3e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI45078.1 - 6.7e-06 25.4 0.4 1.1e-05 24.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KPI45078.1 - 7.7e-06 24.9 0.1 4.8e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KPI45078.1 - 1.8e-05 24.1 0.1 2.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KPI45078.1 - 6.8e-05 22.2 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KPI45078.1 - 7e-05 22.4 0.2 0.00012 21.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KPI45078.1 - 0.00076 18.7 0.3 0.0011 18.1 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KPI45078.1 - 0.00085 19.8 0.1 0.0019 18.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI45078.1 - 0.0026 17.1 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI45078.1 - 0.0048 16.0 0.5 0.027 13.5 0.4 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KPI45078.1 - 0.0049 16.2 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KPI45078.1 - 0.015 15.3 0.8 0.93 9.5 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KPI45078.1 - 0.028 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ank_2 PF12796.7 KPI45079.1 - 4.9e-32 110.4 0.0 8.2e-15 55.2 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Clr5 PF14420.6 KPI45079.1 - 6.5e-17 61.5 1.3 6.5e-17 61.5 1.3 2.4 3 0 0 3 3 2 1 Clr5 domain Ank_5 PF13857.6 KPI45079.1 - 1.5e-15 57.1 0.7 1.4e-06 28.4 0.1 4.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KPI45079.1 - 5.8e-15 53.9 0.0 6.5e-06 26.1 0.1 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KPI45079.1 - 1.3e-14 54.4 0.1 2.5e-09 37.5 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KPI45079.1 - 5.2e-12 45.6 0.1 5.6e-06 26.6 0.1 4.4 3 1 0 3 3 3 2 Ankyrin repeat HET PF06985.11 KPI45079.1 - 1.3e-11 45.0 2.2 2.1e-10 41.1 1.6 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 KPI45079.1 - 3.6e-06 27.0 0.1 1.6e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KPI45079.1 - 0.00018 21.9 0.2 0.00098 19.5 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI45079.1 - 0.0021 18.3 0.0 0.046 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KPI45079.1 - 0.0086 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KPI45079.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KPI45079.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 KPI45079.1 - 0.15 11.9 0.1 0.47 10.3 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase MFS_1 PF07690.16 KPI45080.1 - 7.4e-28 97.5 15.5 7.4e-28 97.5 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DPM3 PF08285.11 KPI45080.1 - 0.45 10.7 2.2 13 6.0 0.0 3.2 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MFS_1 PF07690.16 KPI45081.1 - 5.9e-23 81.4 35.4 3.5e-12 45.9 9.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KPI45081.1 - 1.5e-09 36.9 17.5 0.00073 18.2 4.3 4.0 4 0 0 4 4 4 3 MFS/sugar transport protein Phage_holin_3_6 PF07332.11 KPI45081.1 - 0.0074 16.3 0.6 0.0074 16.3 0.6 5.2 5 2 0 5 5 5 2 Putative Actinobacterial Holin-X, holin superfamily III Fungus-induced PF10917.8 KPI45081.1 - 0.093 13.1 0.3 0.093 13.1 0.3 2.9 2 0 0 2 2 2 0 Fungus-induced protein AATase PF07247.12 KPI45082.1 - 9.4e-13 47.5 0.0 1.6e-07 30.3 0.0 2.9 2 1 0 2 2 2 2 Alcohol acetyltransferase RseA_C PF03873.13 KPI45082.1 - 0.048 13.9 0.5 0.096 12.9 0.1 1.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Cas6 PF09559.10 KPI45083.1 - 0.0076 16.2 0.4 0.0088 16.0 0.4 1.1 1 0 0 1 1 1 1 Cas6 Crispr adh_short PF00106.25 KPI45085.1 - 4.3e-33 114.4 0.0 5.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45085.1 - 1.2e-19 70.9 0.0 1.4e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45085.1 - 0.0088 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 KR domain OSCP PF00213.18 KPI45086.1 - 3.5e-43 147.7 0.6 4e-43 147.5 0.6 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Ank_2 PF12796.7 KPI45087.1 - 2.2e-28 98.7 0.0 1.1e-14 54.8 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KPI45087.1 - 1.5e-24 83.4 2.9 1.6e-07 31.1 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KPI45087.1 - 3.1e-24 84.3 0.3 1.6e-06 28.3 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KPI45087.1 - 6.2e-21 74.5 0.7 2.6e-06 27.8 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KPI45087.1 - 2.3e-19 69.2 1.0 1.1e-05 25.5 0.0 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DIOX_N PF14226.6 KPI45088.1 - 1.1e-15 58.4 0.1 2.6e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI45088.1 - 2.1e-12 47.4 0.0 4.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Gmad2 PF10648.9 KPI45088.1 - 0.084 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Peptidase_S8 PF00082.22 KPI45089.1 - 2.7e-31 108.9 0.4 4.5e-31 108.2 0.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KPI45089.1 - 9.4e-29 99.3 0.5 2.3e-28 98.0 0.5 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KPI45089.1 - 0.00018 22.2 0.1 0.00018 22.2 0.1 2.0 2 0 0 2 2 2 1 Peptidase S8 pro-domain SPC25 PF06703.11 KPI45090.1 - 1.7e-44 151.4 0.0 2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase PF00069.25 KPI45091.1 - 7.5e-61 205.8 0.0 2.4e-60 204.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45091.1 - 3.1e-29 102.1 0.0 6.5e-29 101.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KPI45091.1 - 2.1e-10 40.8 0.0 5.6e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KPI45091.1 - 2e-06 28.0 0.0 6.4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KPI45091.1 - 0.00015 21.2 0.0 0.00088 18.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KPI45091.1 - 0.0026 17.7 0.1 0.028 14.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KPI45091.1 - 0.0035 16.7 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KPI45091.1 - 0.081 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain P34-Arc PF04045.14 KPI45092.1 - 1.1e-106 355.9 0.3 1.6e-106 355.4 0.3 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc GFO_IDH_MocA PF01408.22 KPI45092.1 - 5.5e-16 59.5 0.1 1.6e-15 58.0 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ARPC4 PF05856.12 KPI45092.1 - 0.033 13.8 0.0 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) 2OG-FeII_Oxy_2 PF13532.6 KPI45093.1 - 1.3e-26 94.0 0.0 2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cytotoxic PF09000.10 KPI45093.1 - 0.048 14.0 1.1 0.11 12.8 1.1 1.6 1 0 0 1 1 1 0 Cytotoxic PCM1_C PF15717.5 KPI45093.1 - 0.083 11.6 0.2 3.8 6.1 0.0 2.0 2 0 0 2 2 2 0 Pericentriolar material 1 C terminus Abhydrolase_6 PF12697.7 KPI45095.1 - 7.9e-14 52.8 2.3 1e-13 52.4 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KPI45095.1 - 3.3e-06 26.6 0.0 7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KPI45095.1 - 8e-05 22.3 0.1 0.0092 15.6 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase RelB_transactiv PF16181.5 KPI45095.1 - 0.026 14.8 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 RelB transactivation domain DUF4350 PF14258.6 KPI45095.1 - 0.07 13.6 0.0 0.25 11.8 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Carb_kinase PF01256.17 KPI45096.1 - 2.3e-53 181.2 0.0 3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase FxsA PF04186.13 KPI45096.1 - 0.075 13.2 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Phos_pyr_kin PF08543.12 KPI45096.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase FAD_binding_3 PF01494.19 KPI45097.1 - 5.5e-07 29.1 4.3 0.00069 19.0 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KPI45097.1 - 0.0024 17.9 0.3 0.0086 16.1 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI45097.1 - 0.0033 16.7 0.5 0.0053 16.1 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI45097.1 - 0.0049 17.1 0.5 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI45097.1 - 0.0091 15.3 0.9 0.015 14.6 0.8 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI45097.1 - 0.033 12.9 0.4 0.058 12.1 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 KPI45097.1 - 0.076 12.0 0.0 0.55 9.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 KPI45097.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DNA_mis_repair PF01119.19 KPI45098.1 - 1.6e-13 50.4 0.0 3.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KPI45098.1 - 1.6e-09 37.7 0.7 3.8e-09 36.5 0.7 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPI45098.1 - 2.2e-07 31.4 0.7 7.8e-07 29.6 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SUI1 PF01253.22 KPI45099.1 - 2.5e-24 85.6 0.1 4.8e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 HK_sensor PF16750.5 KPI45099.1 - 0.14 12.4 0.5 0.23 11.8 0.5 1.4 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase MscS_TM PF12794.7 KPI45099.1 - 1.4 7.7 4.0 1.8 7.3 4.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FKBP_N PF01346.18 KPI45099.1 - 5.3 8.1 9.0 37 5.4 9.0 2.1 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase adh_short PF00106.25 KPI45100.1 - 2.7e-24 85.7 0.0 3.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45100.1 - 8.1e-10 38.6 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45100.1 - 0.0002 21.3 0.0 0.0049 16.8 0.0 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KPI45100.1 - 0.023 14.6 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Bromo_TP PF07524.13 KPI45101.1 - 2.2e-13 50.0 0.5 3.8e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 KPI45101.1 - 4.6e-05 23.5 0.0 0.00035 20.6 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF3533 PF12051.8 KPI45102.1 - 1.2e-96 324.0 5.3 1.9e-96 323.3 5.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4658 PF15555.6 KPI45102.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) PTPLA PF04387.14 KPI45102.1 - 0.48 10.2 5.2 2 8.2 0.1 3.1 2 1 1 3 3 3 0 Protein tyrosine phosphatase-like protein, PTPLA SHE3 PF17078.5 KPI45103.1 - 8.1e-10 38.8 28.5 1e-08 35.2 23.3 2.1 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 DUF641 PF04859.12 KPI45103.1 - 0.026 14.9 20.9 0.33 11.3 3.8 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3253 PF11625.8 KPI45103.1 - 0.042 14.1 2.9 0.13 12.5 2.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Baculo_PEP_C PF04513.12 KPI45103.1 - 0.14 12.2 4.8 0.053 13.6 2.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP_C PF03836.15 KPI45103.1 - 0.43 10.7 22.7 0.32 11.1 3.4 2.4 1 1 0 2 2 2 0 RasGAP C-terminus Matrilin_ccoil PF10393.9 KPI45103.1 - 0.92 9.4 4.3 8.1 6.4 0.2 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ADIP PF11559.8 KPI45103.1 - 1.4 8.9 39.2 0.057 13.5 11.1 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_I PF06008.14 KPI45104.1 - 0.0086 15.8 1.0 0.0086 15.8 1.0 1.7 2 0 0 2 2 2 1 Laminin Domain I CxC3 PF18804.1 KPI45104.1 - 0.06 13.2 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases INCENP_ARK-bind PF03941.15 KPI45104.1 - 5.9 6.9 6.1 3.6 7.6 1.4 2.5 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Ada_Zn_binding PF02805.16 KPI45105.1 - 2.7e-24 85.0 6.3 2.7e-24 85.0 6.3 2.0 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_AraC PF00165.23 KPI45105.1 - 0.0037 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KPI45105.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CMD PF02627.20 KPI45107.1 - 0.0001 22.3 0.0 0.00095 19.2 0.0 2.4 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family p450 PF00067.22 KPI45108.1 - 5.3e-63 213.4 0.0 6.5e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-6 PF01912.18 KPI45109.1 - 1.5e-78 262.8 0.2 2.1e-78 262.2 0.2 1.2 1 0 0 1 1 1 1 eIF-6 family Zip PF02535.22 KPI45110.1 - 1.3e-28 100.2 0.0 1.5e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Yippee-Mis18 PF03226.14 KPI45112.1 - 3.2e-06 27.3 0.5 8.8e-06 25.9 0.5 1.7 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PRKG1_interact PF15898.5 KPI45112.1 - 0.078 13.9 4.4 0.19 12.6 4.4 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TolA_bind_tri PF16331.5 KPI45112.1 - 0.14 12.3 8.3 0.038 14.1 3.6 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation CHASE3 PF05227.13 KPI45112.1 - 0.26 11.2 7.4 0.43 10.5 7.4 1.3 1 0 0 1 1 1 0 CHASE3 domain DUF2353 PF09789.9 KPI45112.1 - 0.36 10.2 7.3 0.63 9.4 7.3 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) YabA PF06156.13 KPI45112.1 - 0.46 11.2 3.9 3.8 8.2 3.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA zf-B_box PF00643.24 KPI45112.1 - 1.4 9.2 4.2 20 5.5 0.7 2.3 2 0 0 2 2 2 0 B-box zinc finger p450 PF00067.22 KPI45113.1 - 7.7e-50 170.0 0.0 1.1e-49 169.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 KPI45114.1 - 9.9e-44 147.0 0.0 1.3e-21 76.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KPI45114.1 - 0.00023 21.2 0.0 0.98 9.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif MFS_1 PF07690.16 KPI45115.1 - 3.9e-34 118.1 24.9 5.5e-34 117.6 24.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI45115.1 - 0.00029 20.3 16.1 0.0079 15.5 14.2 2.7 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2929 PF11151.8 KPI45115.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2929) Cys_Met_Meta_PP PF01053.20 KPI45116.1 - 1.4e-18 66.6 0.0 1.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KPI45116.1 - 2.8e-05 23.4 0.0 4.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DUF29 PF01724.16 KPI45117.1 - 0.026 14.8 1.1 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF29 Caprin-1_dimer PF18293.1 KPI45117.1 - 0.066 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Caprin-1 dimerization domain HATPase_c_3 PF13589.6 KPI45118.1 - 0.097 12.5 5.2 1.1 9.1 1.6 2.5 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_2 PF00891.18 KPI45119.1 - 9.8e-30 103.4 0.0 5.7e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KPI45119.1 - 0.017 15.8 0.0 0.048 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KPI45119.1 - 0.019 14.5 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain HECT_2 PF09814.9 KPI45120.1 - 4e-69 233.3 0.4 9.4e-66 222.2 0.4 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding F-box-like PF12937.7 KPI45121.1 - 0.0041 17.0 0.0 0.021 14.7 0.0 2.1 1 1 0 1 1 1 1 F-box-like Macoilin PF09726.9 KPI45122.1 - 0.56 8.7 7.0 0.65 8.5 7.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF3340 PF11818.8 KPI45122.1 - 0.62 10.2 8.6 1.5 9.0 8.6 1.6 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Peptidase_M1 PF01433.20 KPI45124.1 - 4.6e-44 150.6 0.1 6.8e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KPI45124.1 - 2.9e-34 117.6 0.0 5.5e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KPI45124.1 - 1.6e-26 93.6 0.1 2.5e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KPI45124.1 - 0.022 14.4 0.1 0.39 10.3 0.1 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 KPI45124.1 - 0.29 11.5 2.7 5.4 7.4 2.7 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Sugar_tr PF00083.24 KPI45125.1 - 1.1e-85 288.2 19.6 1.4e-85 287.9 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45125.1 - 2.3e-14 53.1 61.4 1.2e-11 44.2 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HemY_N PF07219.13 KPI45126.1 - 0.074 13.3 1.5 0.22 11.7 1.5 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Pyr_redox_2 PF07992.14 KPI45127.1 - 5.4e-17 61.9 0.0 6.4e-15 55.1 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI45127.1 - 7.4e-14 51.7 0.1 2e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI45127.1 - 8.8e-12 44.8 0.0 1.4e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KPI45127.1 - 1.9e-09 36.5 0.0 2.6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI45127.1 - 4.4e-08 33.2 0.2 0.00052 20.2 0.1 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KPI45127.1 - 3.7e-06 26.4 0.4 0.068 12.4 0.5 3.2 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 KPI45127.1 - 6.1e-06 26.7 0.3 0.0075 16.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI45127.1 - 6.9e-06 25.7 0.1 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KPI45127.1 - 0.00011 21.5 0.2 0.024 13.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KPI45127.1 - 0.00036 20.2 0.3 0.3 10.6 0.0 2.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KPI45127.1 - 0.00071 19.7 0.1 0.0068 16.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KPI45127.1 - 0.00075 18.7 2.0 0.44 9.6 0.4 3.3 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 KPI45127.1 - 0.0011 17.8 1.9 0.25 10.0 1.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KPI45127.1 - 0.0012 18.0 0.3 0.92 8.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein SnoaL_2 PF12680.7 KPI45127.1 - 0.0015 19.1 0.5 0.0032 18.1 0.5 1.5 1 0 0 1 1 1 1 SnoaL-like domain GIDA PF01134.22 KPI45127.1 - 0.0017 17.5 0.2 1.6 7.8 0.0 2.6 2 0 0 2 2 2 2 Glucose inhibited division protein A IlvN PF07991.12 KPI45127.1 - 0.0056 16.3 0.1 0.96 9.0 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF4440 PF14534.6 KPI45127.1 - 0.0088 16.4 0.4 0.14 12.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) TrkA_N PF02254.18 KPI45127.1 - 0.017 15.4 0.1 0.17 12.1 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KPI45127.1 - 0.03 13.6 4.1 0.36 10.1 0.8 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KPI45127.1 - 0.033 14.6 0.0 4.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 KPI45127.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.17 KPI45127.1 - 0.078 13.6 1.7 0.53 10.9 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KPI45127.1 - 0.1 12.6 0.0 19 5.2 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KPI45127.1 - 0.13 11.9 0.2 15 5.2 0.1 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GARS_N PF02844.15 KPI45127.1 - 0.14 13.0 0.0 0.48 11.2 0.0 2.0 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain AdoHcyase_NAD PF00670.21 KPI45127.1 - 0.17 12.0 0.5 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KPI45127.1 - 0.17 11.2 1.0 1.8 7.9 0.0 2.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KPI45127.1 - 1 9.2 3.5 3.7 7.4 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 KPI45128.1 - 2.2e-71 240.3 0.0 2.9e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45128.1 - 1.5e-45 155.5 0.0 2.3e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI45128.1 - 3.1e-07 30.0 0.0 7.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KPI45128.1 - 0.0021 17.1 0.1 0.0038 16.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KPI45128.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3439 PF11921.8 KPI45128.1 - 1.9 8.4 5.7 0.5 10.3 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HET PF06985.11 KPI45129.1 - 7.5e-13 49.1 9.7 1.1e-10 42.1 3.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nsp3_PL2pro PF12124.8 KPI45129.1 - 0.18 11.6 0.5 2.2 8.1 0.3 2.3 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain Vac7 PF12751.7 KPI45130.1 - 9.3e-122 407.1 6.6 2.2e-121 405.9 6.6 1.6 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 PTP_tm PF18861.1 KPI45131.1 - 0.0012 18.9 0.1 0.0019 18.2 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J G6B PF15096.6 KPI45131.1 - 0.018 14.8 0.5 0.049 13.4 0.0 1.9 1 1 1 2 2 2 0 G6B family SpoIIIAH PF12685.7 KPI45131.1 - 0.17 11.7 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Pro_Al_protease PF02983.14 KPI45132.1 - 0.027 14.5 0.6 0.065 13.3 0.6 1.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain DUF3453 PF11935.8 KPI45133.1 - 3.7e-65 219.7 0.1 2.5e-63 213.8 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) FdhE PF04216.12 KPI45133.1 - 0.014 15.3 0.1 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DUF3431 PF11913.8 KPI45134.1 - 3.3e-83 278.7 0.0 4.2e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Clr5 PF14420.6 KPI45136.1 - 5.8e-10 39.2 0.0 2e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Clr5 domain TPR_2 PF07719.17 KPI45136.1 - 9.5 6.6 7.3 4.4 7.7 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 KPI45137.1 - 2.5e-37 128.7 0.1 3.2e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI45137.1 - 6.1e-30 104.1 0.0 8.6e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI45137.1 - 9.6e-08 32.1 0.0 3.9e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI45137.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI45137.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI45137.1 - 0.0025 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KPI45137.1 - 0.0027 16.7 0.0 0.0047 16.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPI45137.1 - 0.033 13.3 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KPI45137.1 - 0.034 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KPI45137.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 KPI45137.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arginase PF00491.21 KPI45138.1 - 3.9e-19 69.2 0.0 5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family Amino_oxidase PF01593.24 KPI45139.1 - 1e-42 147.0 0.1 2.4e-42 145.8 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI45139.1 - 5.6e-06 26.5 0.0 1.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI45139.1 - 0.01 15.1 0.0 0.22 10.7 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KPI45139.1 - 0.079 12.2 0.3 0.15 11.2 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain WD40 PF00400.32 KPI45140.1 - 0.00041 21.1 3.1 3.9 8.5 0.1 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat HTH_19 PF12844.7 KPI45140.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2406 PF10295.9 KPI45141.1 - 1.8e-21 76.6 1.1 5.9e-21 74.9 1.1 2.0 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) AFG1_ATPase PF03969.16 KPI45142.1 - 7e-63 212.7 0.0 2.3e-61 207.7 0.0 2.1 2 0 0 2 2 2 1 AFG1-like ATPase GMC_oxred_N PF00732.19 KPI45142.1 - 1e-50 172.8 0.0 1.5e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI45142.1 - 1.2e-21 77.8 0.1 4.7e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase AAA_5 PF07728.14 KPI45142.1 - 5.7e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KPI45142.1 - 0.00041 20.8 0.1 0.15 12.4 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain DAO PF01266.24 KPI45142.1 - 0.00056 19.6 0.2 0.0022 17.7 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KPI45142.1 - 0.012 14.7 0.2 0.097 11.7 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KPI45142.1 - 0.021 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI45142.1 - 0.051 13.8 2.7 0.069 13.4 1.1 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain IstB_IS21 PF01695.17 KPI45142.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Thi4 PF01946.17 KPI45142.1 - 0.075 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KPI45142.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AAA_22 PF13401.6 KPI45142.1 - 0.16 12.2 0.0 0.5 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain VRR_NUC PF08774.11 KPI45143.1 - 1.5e-19 70.1 0.0 5.4e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain FANC_SAP PF18081.1 KPI45143.1 - 0.039 14.1 0.9 0.17 12.0 0.9 2.1 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain DUF1708 PF08101.11 KPI45144.1 - 3e-161 537.4 0.0 4.8e-161 536.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) IBR PF01485.21 KPI45146.1 - 1.9e-14 53.6 26.1 1.1e-08 35.2 8.3 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-UDP PF14569.6 KPI45146.1 - 1.4 9.1 13.0 0.32 11.1 4.0 3.1 2 1 1 3 3 3 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 KPI45146.1 - 1.9 8.9 30.3 0.059 13.7 4.0 3.3 3 0 0 3 3 3 0 Ring finger domain FYVE PF01363.21 KPI45146.1 - 2.6 8.2 21.4 1.6 8.9 2.7 3.5 3 1 0 3 3 3 0 FYVE zinc finger HNF-1_N PF04814.13 KPI45146.1 - 3.8 8.1 9.7 26 5.4 0.0 2.4 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Aspzincin_M35 PF14521.6 KPI45147.1 - 3.1e-08 34.3 0.0 6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KPI45147.1 - 2.6e-05 23.3 0.1 3.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Afi1 PF07792.12 KPI45148.1 - 3.5e-41 140.8 0.1 7e-41 139.8 0.1 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KPI45148.1 - 7.4e-36 122.6 0.0 1.6e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KPI45148.1 - 6.4e-09 35.0 0.0 0.0011 17.8 0.0 3.8 2 2 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.9 KPI45148.1 - 0.00097 18.8 0.0 0.017 14.7 0.0 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) PNGaseA PF12222.8 KPI45149.1 - 1.1e-111 373.8 1.1 1.8e-97 327.0 0.4 2.1 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Arf PF00025.21 KPI45149.1 - 4.4e-58 195.6 0.0 6.5e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KPI45149.1 - 4.5e-09 35.9 0.0 3.7e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KPI45149.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KPI45149.1 - 1.7e-06 28.1 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KPI45149.1 - 6.9e-06 26.3 0.0 2.6e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KPI45149.1 - 0.00083 19.0 0.0 0.002 17.8 0.0 1.6 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 KPI45149.1 - 0.0055 16.1 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AA_permease PF00324.21 KPI45150.1 - 1.9e-132 442.3 33.3 2.2e-132 442.1 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI45150.1 - 3.2e-38 131.7 35.2 4.7e-38 131.1 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease DIOX_N PF14226.6 KPI45151.1 - 0.055 14.2 0.0 0.15 12.9 0.0 1.6 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal PhyH PF05721.13 KPI45151.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_28 PF02636.17 KPI45152.1 - 5e-39 134.5 0.0 8.2e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KPI45152.1 - 0.037 13.9 0.0 0.09 12.6 0.0 1.7 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Glyco_hydro_18 PF00704.28 KPI45154.1 - 6.5e-06 26.1 0.1 1e-05 25.5 0.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hyphal_reg_CWP PF11765.8 KPI45154.1 - 0.1 11.5 0.9 0.13 11.2 0.9 1.3 1 1 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal Phage_CRI PF05144.14 KPI45154.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.3 1 1 0 1 1 1 0 Phage replication protein CRI SUKH_5 PF14567.6 KPI45155.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall MFS_1 PF07690.16 KPI45156.1 - 8.6e-34 117.0 23.6 8.6e-34 117.0 23.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KPI45156.1 - 0.00045 19.2 3.8 0.00045 19.2 3.8 1.9 1 1 0 2 2 2 1 MFS_1 like family PEP_hydrolase PF09370.10 KPI45157.1 - 6.1e-120 399.4 0.1 9.4e-120 398.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like ABC_tran PF00005.27 KPI45158.1 - 4e-09 37.1 0.0 5.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Telomere_reg-2 PF10193.9 KPI45160.1 - 1e-16 61.3 1.6 1.2e-15 57.9 0.1 3.3 3 1 0 3 3 3 1 Telomere length regulation protein Amidase PF01425.21 KPI45161.1 - 1.9e-73 248.0 3.0 2.5e-73 247.6 3.0 1.1 1 0 0 1 1 1 1 Amidase RNA_GG_bind PF10258.9 KPI45161.1 - 0.25 11.4 0.0 0.47 10.5 0.0 1.3 1 0 0 1 1 1 0 PHAX RNA-binding domain tRNA-synt_2 PF00152.20 KPI45162.1 - 2.5e-69 233.8 0.0 3.9e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KPI45162.1 - 1.2e-08 34.3 0.0 2.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KPI45162.1 - 0.00044 20.2 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3439 PF11921.8 KPI45162.1 - 6.5 6.7 6.6 15 5.6 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2401 PF10287.9 KPI45163.1 - 2.7e-79 266.0 0.3 4.4e-79 265.3 0.0 1.5 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KPI45163.1 - 1.8e-25 89.1 0.1 4.7e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) ADH_N PF08240.12 KPI45166.1 - 5.3e-20 71.3 0.3 1e-19 70.4 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI45166.1 - 6.9e-16 58.4 0.1 1.1e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KPI45166.1 - 0.0002 21.2 0.5 0.0002 21.2 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KPI45166.1 - 0.00063 20.8 0.0 0.0011 20.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI45166.1 - 0.002 17.6 0.1 0.0036 16.8 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DAO PF01266.24 KPI45166.1 - 0.15 11.6 1.4 7.1 6.1 1.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase CPSF_A PF03178.15 KPI45167.1 - 1.2e-72 245.0 0.0 1.3e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Adaptin_N PF01602.20 KPI45168.1 - 6.9e-113 378.0 0.1 9.4e-113 377.5 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KPI45168.1 - 2e-54 183.9 4.1 4e-54 182.8 4.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KPI45168.1 - 1.1e-32 112.5 0.8 1.3e-31 109.1 0.2 2.7 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KPI45168.1 - 3.6e-19 68.9 2.9 3.5e-12 46.6 0.0 5.4 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KPI45168.1 - 4e-07 30.2 11.7 0.014 15.4 0.1 5.1 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 DUF5010 PF16402.5 KPI45168.1 - 0.0032 16.3 0.0 0.14 10.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5010) HEAT_PBS PF03130.16 KPI45168.1 - 0.021 15.4 0.1 11 7.0 0.0 3.6 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KPI45168.1 - 0.04 14.1 0.6 8.4 6.6 0.0 3.7 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KPI45168.1 - 0.055 13.7 11.2 0.42 11.0 0.3 5.6 7 0 0 7 7 6 0 HEAT repeat HEAT_EZ PF13513.6 KPI45168.1 - 0.069 13.7 2.1 0.17 12.4 0.5 2.7 2 0 0 2 2 2 0 HEAT-like repeat NPA PF16469.5 KPI45168.1 - 0.15 12.7 0.1 0.48 11.0 0.0 1.9 2 0 0 2 2 1 0 Nematode polyprotein allergen ABA-1 RICTOR_M PF14666.6 KPI45168.1 - 0.22 11.3 2.3 12 5.8 0.0 3.6 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Asp_protease_2 PF13650.6 KPI45169.1 - 0.022 15.4 0.0 0.052 14.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Ribosomal_L29e PF01779.17 KPI45170.1 - 1.3e-08 35.0 0.8 2.5e-08 34.1 0.8 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Vps5 PF09325.10 KPI45171.1 - 2.6e-73 246.5 1.2 2.6e-73 246.5 1.2 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KPI45171.1 - 1.9e-26 92.2 0.1 3.8e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KPI45171.1 - 0.027 14.0 0.3 1.3 8.4 0.0 2.2 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein DLH PF01738.18 KPI45173.1 - 3e-21 76.0 0.0 3.5e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KPI45173.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family RhoGAP PF00620.27 KPI45174.1 - 3.1e-35 121.2 0.1 6.2e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KPI45174.1 - 9.7e-33 112.2 33.5 2.9e-12 46.6 5.4 4.8 5 0 0 5 5 5 4 LIM domain zf-ACC PF17848.1 KPI45174.1 - 0.7 10.0 4.4 20 5.4 0.1 3.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_4 PF13894.6 KPI45174.1 - 4.7 8.3 9.3 1.8 9.6 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger IDO PF01231.18 KPI45175.1 - 2.8e-144 481.1 0.0 3.2e-144 480.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase KR PF08659.10 KPI45176.1 - 8.4e-64 214.8 0.2 8.4e-64 214.8 0.2 3.4 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 KPI45176.1 - 2.4e-52 178.4 0.7 4.5e-52 177.5 0.2 1.8 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KPI45176.1 - 2.4e-47 161.6 0.0 5.3e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KPI45176.1 - 4.6e-41 141.1 0.0 5.4e-31 108.1 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KPI45176.1 - 3.7e-36 123.7 0.0 8.8e-36 122.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 KPI45176.1 - 8.4e-21 74.3 1.3 2.6e-19 69.5 0.3 3.5 4 0 0 4 4 4 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KPI45176.1 - 3.5e-19 69.4 0.0 3.7e-18 66.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KPI45176.1 - 3e-17 63.9 0.1 1.7e-15 58.2 0.0 3.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KPI45176.1 - 1.5e-14 54.4 0.1 9.7e-14 51.8 0.1 2.3 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KPI45176.1 - 4.1e-14 53.0 0.0 9e-13 48.8 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KPI45176.1 - 5.7e-13 48.8 0.8 4.1e-12 46.0 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KPI45176.1 - 6.2e-12 46.0 0.0 2.4e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI45176.1 - 8.6e-12 45.2 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45176.1 - 2.3e-11 43.7 0.0 7.2e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KPI45176.1 - 4.6e-08 32.9 0.0 1.7e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 KPI45176.1 - 4.3e-06 26.6 0.2 1.2e-05 25.2 0.2 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 KPI45176.1 - 3.3e-05 23.3 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KPI45176.1 - 0.00013 21.8 0.1 0.0003 20.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 KPI45176.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase DUF3336 PF11815.8 KPI45177.1 - 4.6e-35 120.3 0.3 8.2e-35 119.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KPI45177.1 - 1.9e-17 64.1 0.0 1.2e-16 61.5 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Glyco_hydro_63 PF03200.16 KPI45178.1 - 1.7e-07 30.4 9.6 4.3e-06 25.8 0.5 4.0 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 KPI45178.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein zf-RING_2 PF13639.6 KPI45179.1 - 0.0001 22.6 8.5 0.00015 22.0 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KPI45179.1 - 0.00022 20.9 2.5 0.0006 19.5 2.5 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KPI45179.1 - 0.00037 20.4 5.7 0.0006 19.7 5.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPI45179.1 - 0.0034 17.2 9.2 0.012 15.4 9.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI45179.1 - 0.0036 17.3 3.6 0.0064 16.5 3.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_9 PF13901.6 KPI45179.1 - 0.016 15.2 4.7 0.023 14.7 4.7 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 KPI45179.1 - 0.031 14.2 5.1 0.052 13.4 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KPI45179.1 - 0.031 14.1 7.2 0.079 12.8 7.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KPI45179.1 - 0.29 11.5 8.8 0.61 10.4 8.8 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KPI45179.1 - 0.41 10.6 8.2 1.6 8.7 8.7 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KPI45179.1 - 0.94 9.6 5.1 2 8.5 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KPI45179.1 - 3.1 8.0 7.9 13 6.1 7.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Pyr_redox_2 PF07992.14 KPI45180.1 - 2.6e-10 40.0 0.0 2.6e-09 36.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI45180.1 - 1.1e-07 30.7 0.0 1e-06 27.5 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KPI45180.1 - 0.00012 22.1 0.0 0.01 15.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KPI45180.1 - 0.00015 21.1 0.0 0.0004 19.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI45180.1 - 0.0012 18.1 0.3 0.0012 18.1 0.3 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KPI45180.1 - 0.0014 18.7 0.2 0.0053 16.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KPI45180.1 - 0.0022 18.5 1.4 0.01 16.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI45180.1 - 0.0022 18.2 0.2 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI45180.1 - 0.038 13.3 0.5 0.22 10.8 0.9 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KPI45180.1 - 0.094 13.2 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF498 PF04430.14 KPI45180.1 - 0.13 12.3 0.0 18 5.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF498/DUF598) DHDPS PF00701.22 KPI45182.1 - 6.3e-38 130.1 0.0 7.4e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ANAPC4_WD40 PF12894.7 KPI45183.1 - 7e-07 29.5 0.1 0.00019 21.7 0.0 2.8 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI45183.1 - 6.4e-05 23.7 9.0 0.19 12.6 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat LisH PF08513.11 KPI45183.1 - 0.0082 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 LisH Coatomer_WDAD PF04053.14 KPI45183.1 - 0.021 13.9 0.1 0.043 12.9 0.1 1.4 2 0 0 2 2 2 0 Coatomer WD associated region PQQ PF01011.21 KPI45183.1 - 0.094 12.7 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat p450 PF00067.22 KPI45184.1 - 7.1e-93 311.8 0.0 8.8e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CCSAP PF15748.5 KPI45186.1 - 0.019 15.2 0.5 0.029 14.5 0.1 1.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated XPG_I PF00867.18 KPI45187.1 - 2.2e-31 108.0 1.4 4.7e-31 107.0 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KPI45187.1 - 2.4e-16 60.0 0.0 8.7e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KPI45187.1 - 8.9e-06 26.2 1.0 3.2e-05 24.5 0.0 2.4 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KPI45187.1 - 0.025 15.2 0.0 0.062 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DDHD PF02862.17 KPI45187.1 - 0.61 10.2 3.5 8 6.6 2.5 2.1 2 0 0 2 2 2 0 DDHD domain Glyco_trans_2_3 PF13632.6 KPI45188.1 - 1.2e-44 152.6 7.1 1.2e-44 152.6 7.1 2.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KPI45188.1 - 0.00037 20.4 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KPI45188.1 - 0.012 15.0 0.0 0.035 13.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 Img2 PF05046.14 KPI45188.1 - 0.14 12.5 0.0 0.6 10.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) SnoaL_4 PF13577.6 KPI45189.1 - 2e-07 31.2 0.0 3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain p450 PF00067.22 KPI45191.1 - 2.8e-61 207.7 0.0 3.7e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DnaJ_C PF01556.18 KPI45192.1 - 2.1e-22 79.8 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KPI45192.1 - 4.3e-21 74.8 0.6 9.3e-21 73.7 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KPI45192.1 - 9.8e-14 51.5 19.9 1.6e-13 50.8 19.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KPI45192.1 - 0.00032 20.6 8.4 0.022 14.7 1.8 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KPI45192.1 - 0.0033 17.4 7.9 0.1 12.6 1.4 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KPI45192.1 - 0.2 12.1 7.7 0.25 11.7 1.7 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar TackOD1 PF18551.1 KPI45192.1 - 1.2 8.8 6.8 0.55 9.9 0.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 KPI45192.1 - 5.5 7.1 11.8 23 5.1 11.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Abhydrolase_3 PF07859.13 KPI45194.1 - 8.1e-41 140.2 0.0 2.1e-29 102.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KPI45194.1 - 2e-05 23.7 0.0 6.8e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KPI45194.1 - 0.0015 18.1 0.4 0.33 10.4 0.0 3.0 2 1 1 3 3 3 2 Prolyl oligopeptidase family AXE1 PF05448.12 KPI45194.1 - 0.035 12.8 0.0 0.94 8.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) SIR2 PF02146.17 KPI45195.1 - 1e-30 107.0 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TcdA_TcdB PF12919.7 KPI45198.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain zf-H2C2_2 PF13465.6 KPI45199.1 - 2.2e-10 40.5 13.5 3.3e-05 24.1 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KPI45199.1 - 1.9e-09 37.4 14.3 1.9e-05 24.9 4.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI45199.1 - 6.2e-07 29.7 12.4 0.0011 19.6 3.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KPI45199.1 - 2.8e-06 27.5 1.3 1.5e-05 25.2 1.3 2.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KPI45199.1 - 5.8e-05 23.0 9.5 0.0001 22.2 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI45199.1 - 0.00055 20.1 5.1 0.00064 19.9 1.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KPI45199.1 - 0.048 14.0 1.2 0.048 14.0 1.2 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KPI45199.1 - 0.084 12.8 3.8 3.3 7.7 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KPI45199.1 - 0.23 11.3 6.8 5.2 6.9 0.8 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Actin_micro PF17003.5 KPI45199.1 - 0.27 10.4 0.3 0.37 9.9 0.3 1.1 1 0 0 1 1 1 0 Putative actin-like family Nuc_sug_transp PF04142.15 KPI45200.1 - 2.8e-104 348.7 27.3 4.8e-103 344.6 27.3 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KPI45200.1 - 1.3e-07 31.2 17.1 1.3e-07 31.2 17.1 1.8 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 KPI45200.1 - 8.2e-05 22.8 27.3 0.00083 19.5 3.6 2.5 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KPI45200.1 - 0.00086 18.6 23.6 0.003 16.9 22.6 2.1 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Pex24p PF06398.11 KPI45200.1 - 0.13 11.2 0.6 0.37 9.7 0.0 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3602 PF12223.8 KPI45201.1 - 6.2e-21 74.8 9.8 1.6e-20 73.4 4.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) MFS_1 PF07690.16 KPI45202.1 - 1e-30 106.9 21.0 1e-30 106.9 21.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SNF2_N PF00176.23 KPI45204.1 - 5.7e-65 219.3 0.0 8.7e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI45204.1 - 7e-12 45.7 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI45204.1 - 6.6e-05 23.0 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KPI45204.1 - 0.00014 21.6 0.0 0.00038 20.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Endonuclease_7 PF02945.15 KPI45204.1 - 0.049 13.5 1.3 0.14 12.1 1.3 1.8 1 0 0 1 1 1 0 Recombination endonuclease VII zf-RING_5 PF14634.6 KPI45204.1 - 0.28 11.2 4.6 0.55 10.2 4.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KPI45204.1 - 1.5 8.7 4.9 0.56 10.1 1.9 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KPI45204.1 - 2.4 8.1 4.1 5.7 6.9 4.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Chal_sti_synt_N PF00195.19 KPI45205.1 - 3.6e-24 85.5 0.1 4.8e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 KPI45205.1 - 2.9e-13 50.1 0.0 5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 KPI45205.1 - 1.3e-07 31.2 0.1 2.9e-07 30.1 0.2 1.5 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KPI45205.1 - 5.7e-05 22.9 0.2 0.00015 21.6 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Phage_tail_X PF05489.12 KPI45205.1 - 0.066 12.9 0.0 0.96 9.2 0.0 2.6 3 0 0 3 3 3 0 Phage Tail Protein X ACP_syn_III_C PF08541.10 KPI45205.1 - 0.072 13.3 0.0 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NPV_P10 PF05531.12 KPI45206.1 - 2.2 8.8 10.3 96 3.6 0.1 5.2 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Leu_zip PF15294.6 KPI45206.1 - 2.9 7.3 11.5 0.076 12.5 0.6 2.8 2 1 1 3 3 3 0 Leucine zipper adh_short PF00106.25 KPI45207.1 - 4.9e-22 78.4 0.0 9.5e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45207.1 - 1.4e-16 60.8 0.0 4.1e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KPI45207.1 - 0.0064 16.2 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 KPI45207.1 - 0.043 13.7 0.1 0.25 11.3 0.1 2.0 1 1 0 1 1 1 0 KR domain Hydrolase_4 PF12146.8 KPI45208.1 - 8.4e-39 133.3 0.0 1.9e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI45208.1 - 1.7e-11 45.2 2.7 6.4e-11 43.3 0.5 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI45208.1 - 2.1e-05 24.3 0.0 8.6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KPI45208.1 - 8e-05 22.6 0.0 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI45208.1 - 0.00025 20.6 0.0 0.078 12.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KPI45208.1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Acetyltransf_10 PF13673.7 KPI45208.1 - 0.036 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI45208.1 - 0.083 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 KPI45208.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI45208.1 - 0.15 12.5 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3700 PF12481.8 KPI45209.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein HPP PF04982.13 KPI45210.1 - 6.8e-24 84.4 5.0 6.8e-24 84.4 5.0 1.7 1 1 0 1 1 1 1 HPP family DLH PF01738.18 KPI45211.1 - 6.2e-17 61.9 0.0 7.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KPI45211.1 - 0.014 15.0 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 KPI45212.1 - 2.2e-16 59.7 0.1 5e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI45212.1 - 3.3e-06 27.1 11.4 5.3e-06 26.5 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnd2 PF05786.14 KPI45212.1 - 3.4 6.2 10.2 0.18 10.4 1.8 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 F-box PF00646.33 KPI45213.1 - 0.0012 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain KASH_CCD PF14662.6 KPI45213.1 - 0.004 17.0 1.4 0.0084 16.0 1.4 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TFR_dimer PF04253.15 KPI45213.1 - 0.0073 16.4 0.9 0.018 15.1 0.1 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain DUF812 PF05667.11 KPI45213.1 - 0.013 14.4 1.4 0.022 13.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2205 PF10224.9 KPI45213.1 - 0.022 14.8 1.6 0.053 13.5 1.6 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Filament PF00038.21 KPI45213.1 - 0.025 14.2 1.0 0.05 13.2 1.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF2408 PF10303.9 KPI45213.1 - 0.035 14.7 0.6 2 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) RmuC PF02646.16 KPI45213.1 - 0.039 13.1 0.8 0.065 12.3 0.8 1.2 1 0 0 1 1 1 0 RmuC family F-box-like PF12937.7 KPI45213.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Jnk-SapK_ap_N PF09744.9 KPI45213.1 - 0.049 13.9 0.8 0.14 12.4 0.8 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KPI45213.1 - 0.057 13.4 4.3 0.098 12.7 1.7 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KPI45213.1 - 0.086 12.9 3.2 0.22 11.6 3.2 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 KPI45213.1 - 0.089 13.2 7.3 0.23 11.9 5.5 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper CLZ PF16526.5 KPI45213.1 - 0.1 13.0 3.0 0.33 11.3 3.0 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 KPI45213.1 - 0.1 11.9 4.3 0.24 10.7 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 KPI45213.1 - 0.14 12.4 0.8 0.32 11.2 0.8 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 KPI45213.1 - 0.19 12.1 5.7 0.52 10.7 5.7 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF16 PF01519.16 KPI45213.1 - 0.26 11.8 0.8 0.82 10.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 HALZ PF02183.18 KPI45213.1 - 0.43 10.8 4.4 5.2 7.4 1.4 2.9 2 1 1 3 3 2 0 Homeobox associated leucine zipper DUF724 PF05266.14 KPI45213.1 - 0.51 10.1 5.2 0.31 10.8 1.2 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 KPI45213.1 - 0.74 10.0 6.7 0.29 11.3 4.0 1.6 2 0 0 2 2 1 0 Tropomyosin like DUF4200 PF13863.6 KPI45213.1 - 1.5 9.3 6.8 0.14 12.6 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) EMP24_GP25L PF01105.24 KPI45213.1 - 5.7 6.8 5.3 0.5 10.3 0.7 1.6 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 KPI45213.1 - 7.2 6.8 11.8 0.57 10.3 2.6 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 KPI45213.1 - 8.2 6.7 8.4 3.4 7.9 0.9 2.8 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding Amidohydro_1 PF01979.20 KPI45214.1 - 8.4e-62 209.5 0.1 1.2e-61 208.9 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI45214.1 - 1.1e-08 35.1 0.1 6.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Sugar_tr PF00083.24 KPI45215.1 - 2.1e-79 267.5 26.8 2.6e-79 267.2 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45215.1 - 3e-32 111.9 45.3 4.3e-29 101.5 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Golgin_A5 PF09787.9 KPI45215.1 - 0.29 10.6 0.0 0.39 10.2 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3792 PF12670.7 KPI45215.1 - 6.8 6.9 21.1 15 5.8 7.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Glyco_transf_28 PF03033.20 KPI45216.1 - 7.9e-17 61.6 0.1 6.5e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KPI45216.1 - 1e-06 29.0 0.0 4.8e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KPI45216.1 - 3e-05 23.0 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KPI45216.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 KPI45216.1 - 0.16 11.8 0.7 1.1 9.0 0.5 2.4 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal But2 PF09792.9 KPI45217.1 - 1.6e-32 112.8 1.6 2e-32 112.6 1.6 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Topoisom_I PF01028.20 KPI45218.1 - 1.1e-96 322.6 9.8 1.1e-96 322.6 9.8 2.2 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KPI45218.1 - 1.6e-96 321.9 4.6 1.6e-96 321.9 4.6 3.8 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KPI45218.1 - 1.7e-34 117.5 1.2 9.4e-34 115.2 1.2 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF1464 PF07318.12 KPI45218.1 - 0.84 8.7 2.6 1.8 7.6 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) HLH PF00010.26 KPI45219.1 - 0.0031 17.5 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LAP1C PF05609.12 KPI45219.1 - 5.9 5.9 9.9 8 5.4 9.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 KPI45219.1 - 9.1 4.7 10.7 11 4.4 10.7 1.1 1 0 0 1 1 1 0 Macoilin family PhyH PF05721.13 KPI45221.1 - 5.6e-21 75.8 0.0 7.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AIM3 PF17096.5 KPI45222.1 - 0.025 15.5 4.6 0.59 11.1 1.6 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 CD20 PF04103.15 KPI45222.1 - 0.047 13.8 2.1 0.73 9.9 2.1 2.3 1 1 0 1 1 1 0 CD20-like family TMEMspv1-c74-12 PF11044.8 KPI45222.1 - 0.087 12.8 0.2 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein LRR_6 PF13516.6 KPI45223.1 - 2.4e-13 48.9 4.5 0.087 12.9 0.0 8.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KPI45223.1 - 1.6e-08 34.7 7.1 0.82 10.2 0.0 6.1 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KPI45223.1 - 0.0035 17.7 0.9 1.3e+02 3.8 0.0 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat ketoacyl-synt PF00109.26 KPI45223.1 - 0.39 10.3 1.9 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF740 PF05340.12 KPI45223.1 - 3.9 6.1 8.7 5.2 5.7 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) HAD_2 PF13419.6 KPI45224.1 - 7e-12 45.8 0.0 8.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KPI45224.1 - 4.8e-09 36.8 0.0 7.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KPI45224.1 - 0.0014 18.6 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NUFIP1 PF10453.9 KPI45225.1 - 6.1e-10 38.8 0.9 6.1e-10 38.8 0.9 2.3 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 KPI45225.1 - 1.2e-06 28.2 5.8 2.2e-06 27.3 5.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KPI45225.1 - 1.5e-06 27.9 5.2 3.3e-06 26.8 5.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPI45225.1 - 3.9e-05 23.5 5.8 6.6e-05 22.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KPI45225.1 - 0.1 13.3 0.0 0.1 13.3 0.0 2.4 2 1 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KPI45225.1 - 0.51 10.9 2.8 0.83 10.2 2.8 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF4407 PF14362.6 KPI45225.1 - 8.3 5.7 14.4 12 5.1 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRF-TF PF00319.18 KPI45226.1 - 3.2e-24 84.2 0.2 4.7e-24 83.6 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1829 PF08862.10 KPI45227.1 - 0.00095 19.6 1.5 69 4.0 0.0 5.6 2 1 7 9 9 9 3 Domain of unknown function DUF1829 Pirin PF02678.16 KPI45228.1 - 7.1e-31 106.4 0.2 6.8e-30 103.2 0.1 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KPI45228.1 - 1.4e-25 89.7 0.1 3.2e-24 85.3 0.1 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KPI45228.1 - 7.4e-06 25.6 0.5 0.00025 20.7 0.3 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KPI45228.1 - 0.01 15.5 0.1 0.033 13.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) EthD PF07110.11 KPI45229.1 - 0.00039 21.5 0.0 0.00071 20.7 0.0 1.4 1 1 0 1 1 1 1 EthD domain MmgE_PrpD PF03972.14 KPI45231.1 - 5.5e-54 183.4 1.4 6.6e-54 183.1 1.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family tRNA_SAD PF07973.14 KPI45231.1 - 0.12 12.5 0.0 5.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Threonyl and Alanyl tRNA synthetase second additional domain Peroxin-13_N PF04088.13 KPI45232.1 - 4.1e-30 105.0 4.0 6.2e-30 104.4 4.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Dscam_C PF12355.8 KPI45232.1 - 1.1 10.2 10.3 0.4 11.6 7.4 1.9 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal ARS2 PF04959.13 KPI45232.1 - 4.6 7.6 5.0 6.7 7.0 5.0 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 MMS1_N PF10433.9 KPI45233.1 - 4.6e-08 32.2 0.0 6.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactamase_B_2 PF12706.7 KPI45234.1 - 3.9e-15 55.9 0.7 4.3e-14 52.5 0.3 2.4 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KPI45234.1 - 3.2e-12 46.6 1.8 2.3e-11 43.9 1.8 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KPI45234.1 - 0.00069 19.7 4.2 0.00069 19.7 4.2 1.9 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily End3 PF12761.7 KPI45235.1 - 2.6e-65 220.3 2.5 4e-65 219.7 2.5 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KPI45235.1 - 3.2e-47 158.8 0.0 4.2e-45 152.0 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KPI45235.1 - 4.8e-08 32.0 0.5 2.7e-07 29.7 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KPI45235.1 - 2.2e-07 31.2 0.7 3.6e-06 27.3 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KPI45235.1 - 6.9e-05 22.5 0.1 0.00044 20.0 0.2 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KPI45235.1 - 8.9e-05 22.3 0.1 0.0032 17.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KPI45235.1 - 0.0039 16.6 0.2 0.0096 15.4 0.2 1.7 1 0 0 1 1 1 1 EF hand CENP-F_leu_zip PF10473.9 KPI45235.1 - 0.034 14.2 1.6 0.034 14.2 1.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KPI45235.1 - 5.2 6.3 9.2 9.1 5.5 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FOXP-CC PF16159.5 KPI45237.1 - 0.0016 19.0 7.3 0.012 16.3 1.7 2.9 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KPI45237.1 - 0.009 16.4 23.8 0.46 11.1 0.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type 2-Hacid_dh_C PF02826.19 KPI45238.1 - 1.4e-46 158.1 0.0 2.9e-46 157.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KPI45238.1 - 0.00065 20.1 0.0 0.005 17.3 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 KPI45238.1 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.27 KPI45238.1 - 0.005 17.4 0.0 0.0092 16.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KPI45238.1 - 0.0072 16.8 0.1 0.019 15.5 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh PF00389.30 KPI45238.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KPI45238.1 - 0.031 14.4 0.0 0.093 12.8 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.14 KPI45238.1 - 0.14 11.3 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YafQ_toxin PF15738.5 KPI45238.1 - 0.18 12.2 0.3 0.42 11.0 0.3 1.6 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF3694 PF12473.8 KPI45239.1 - 1.3e-39 136.3 0.0 2.4e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein SAMP PF05924.11 KPI45239.1 - 0.07 12.4 0.5 0.18 11.2 0.5 1.7 1 0 0 1 1 1 0 SAMP Motif PH PF00169.29 KPI45239.1 - 0.075 13.5 0.0 0.33 11.5 0.0 2.1 1 1 0 1 1 1 0 PH domain Epimerase PF01370.21 KPI45240.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI45240.1 - 0.0059 16.5 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPI45240.1 - 0.015 14.4 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein ICL PF00463.21 KPI45240.1 - 0.15 10.5 0.1 0.33 9.4 0.0 1.5 2 0 0 2 2 2 0 Isocitrate lyase family NAD_binding_10 PF13460.6 KPI45241.1 - 8.8e-05 22.5 0.0 0.0001 22.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI45241.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldl_recept_b PF00058.17 KPI45241.1 - 0.033 14.7 0.4 0.074 13.6 0.1 1.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Polysacc_synt_2 PF02719.15 KPI45241.1 - 0.085 12.0 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.8 KPI45242.1 - 0.00029 19.8 0.0 0.00045 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSP90 PF00183.18 KPI45243.1 - 4e-53 181.1 19.8 2.1e-39 135.8 3.5 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KPI45243.1 - 3e-15 56.7 0.1 4.7e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KPI45243.1 - 4.9e-10 39.4 0.1 1.3e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YqfQ PF14181.6 KPI45243.1 - 0.73 10.0 5.1 2.2 8.5 5.1 1.8 1 0 0 1 1 1 0 YqfQ-like protein GST_C PF00043.25 KPI45244.1 - 1.6e-09 37.8 0.0 3.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI45244.1 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KPI45244.1 - 4.5e-06 26.8 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KPI45244.1 - 0.0055 17.1 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Plasmodium_Vir PF05795.11 KPI45245.1 - 2.1 7.6 3.2 3.2 7.1 3.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cadherin_C PF01049.17 KPI45246.1 - 0.023 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic region DUF2353 PF09789.9 KPI45246.1 - 0.072 12.4 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF1639 PF07797.14 KPI45246.1 - 0.16 12.0 0.2 0.34 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Cys_Met_Meta_PP PF01053.20 KPI45247.1 - 6.8e-136 452.8 0.0 8.3e-136 452.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RNA_pol_Rbc25 PF08292.12 KPI45247.1 - 2.1e-29 102.4 0.0 4.1e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KPI45247.1 - 2.5e-15 56.6 0.0 1e-14 54.7 0.0 2.1 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aminotran_1_2 PF00155.21 KPI45247.1 - 6.1e-09 35.5 0.0 9.6e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI45247.1 - 3e-06 26.4 0.4 1e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KPI45247.1 - 1.7e-05 24.3 0.3 2.7e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KPI45247.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase RRM_1 PF00076.22 KPI45248.1 - 7.7e-13 48.1 0.1 4.5e-09 36.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 KPI45248.1 - 1.2 7.7 8.5 2 7.0 8.5 1.3 1 0 0 1 1 1 0 Hamartin protein DUF4187 PF13821.6 KPI45249.1 - 6.5e-22 77.1 1.7 1.5e-21 75.9 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KPI45249.1 - 2.1e-10 40.3 0.2 5.1e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 G-patch domain Tyrosinase PF00264.20 KPI45250.1 - 2.3e-52 178.5 5.8 2.3e-52 178.5 5.8 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KPI45250.1 - 1.4e-22 80.6 0.0 2.6e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain AdoHcyase PF05221.17 KPI45251.1 - 1.7e-128 428.0 0.0 1.6e-72 244.2 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KPI45251.1 - 8.2e-83 276.3 2.3 1.3e-82 275.7 2.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KPI45251.1 - 3.9e-06 26.4 0.2 7.6e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KPI45251.1 - 0.002 17.8 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KPI45251.1 - 0.021 14.5 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KPI45251.1 - 0.038 14.2 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain SH3_2 PF07653.17 KPI45252.1 - 1.8e-10 40.3 0.0 2.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI45252.1 - 6.8e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KPI45252.1 - 6e-07 29.2 0.0 9.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peroxin-13_N PF04088.13 KPI45252.1 - 1.5e-05 25.3 0.1 2.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region hSH3 PF14603.6 KPI45252.1 - 0.003 18.0 0.0 0.0065 16.9 0.0 1.5 2 0 0 2 2 2 1 Helically-extended SH3 domain EP400_N PF15790.5 KPI45253.1 - 0.00036 19.5 1.9 0.00088 18.2 1.9 1.6 1 0 0 1 1 1 1 E1A-binding protein p400, N-terminal MPTase-PolyVal PF18818.1 KPI45254.1 - 0.13 12.3 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Metallopeptidase superfamily domain THF_DHG_CYH PF00763.23 KPI45256.1 - 3.5e-24 85.3 0.1 5.7e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KPI45256.1 - 4.3e-12 45.6 0.0 5.5e-09 35.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-CCCH PF00642.24 KPI45259.1 - 1.3e-17 63.2 30.3 1.7e-06 27.8 0.4 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KPI45259.1 - 2.8e-13 49.4 38.8 2.6e-06 27.3 2.6 5.4 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KPI45259.1 - 1.8e-09 38.3 30.8 1.3e-05 25.8 1.7 5.5 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KPI45259.1 - 5e-05 23.0 1.0 5e-05 23.0 1.0 5.3 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KPI45259.1 - 0.65 10.6 36.6 6.1 7.5 1.1 5.4 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KPI45259.1 - 1.1 9.5 22.0 2.7 8.3 3.3 3.5 1 1 1 3 3 3 0 Zinc-finger containing family PPR_1 PF12854.7 KPI45259.1 - 7.4 6.4 6.4 19 5.1 0.1 3.2 3 0 0 3 3 3 0 PPR repeat Aminotran_5 PF00266.19 KPI45261.1 - 5.2e-10 38.8 0.0 1.5e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DPRP PF04244.13 KPI45261.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Fungal_trans PF04082.18 KPI45262.1 - 2.4e-07 30.1 0.0 7.6e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI45262.1 - 0.011 15.8 5.3 0.02 15.0 5.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 KPI45263.1 - 2.4e-14 53.2 11.4 3.1e-05 24.2 3.8 5.3 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI45263.1 - 2.8e-12 46.2 13.1 9.2e-10 38.2 3.9 4.7 3 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KPI45263.1 - 3.5e-07 29.9 6.1 0.0059 16.1 0.4 2.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 KPI45263.1 - 0.00083 19.6 8.0 5.4 8.0 0.3 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KPI45263.1 - 0.93 9.7 12.3 6.5 7.1 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Amidohydro_2 PF04909.14 KPI45264.1 - 2.2e-37 129.4 0.7 2.7e-37 129.1 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.28 KPI45265.1 - 1.2e-21 76.6 0.3 1.3e-21 76.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 KPI45265.1 - 0.015 15.4 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H adh_short PF00106.25 KPI45266.1 - 1.5e-42 145.3 0.1 2.1e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45266.1 - 1.1e-38 133.1 0.3 1.5e-38 132.7 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45266.1 - 6.1e-10 39.3 0.3 9.4e-10 38.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI45266.1 - 0.00015 21.3 0.1 0.00034 20.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI45266.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KPI45266.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family VMA21 PF09446.10 KPI45268.1 - 0.00056 20.0 13.0 0.0039 17.3 13.0 1.9 1 1 0 1 1 1 1 VMA21-like domain RasGEF PF00617.19 KPI45269.1 - 2.2e-42 145.2 0.0 4.7e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPI45269.1 - 5.9e-11 42.5 0.0 1.5e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KPI45269.1 - 9.9e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Ras family MFS_1 PF07690.16 KPI45271.1 - 8e-51 173.0 52.9 2.3e-48 164.9 55.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI45271.1 - 1.1e-18 67.1 17.7 1.4e-18 66.7 17.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPI45271.1 - 3.9e-13 49.1 11.7 3.9e-13 49.1 11.7 3.6 3 0 0 3 3 3 1 Sugar (and other) transporter Phage_Gp23 PF10669.9 KPI45271.1 - 0.012 15.9 2.0 0.034 14.5 2.0 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1180 PF06679.12 KPI45271.1 - 0.2 12.1 1.4 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2681 PF10883.8 KPI45271.1 - 0.29 11.6 1.1 0.76 10.2 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Glyco_transf_25 PF01755.17 KPI45272.1 - 3.6e-07 30.3 0.1 6.7e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) CHASE8 PF17152.4 KPI45272.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain 2-Hacid_dh_C PF02826.19 KPI45273.1 - 3.8e-40 137.2 0.8 7.1e-23 80.9 0.0 2.8 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KPI45273.1 - 0.055 13.8 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IlvN PF07991.12 KPI45273.1 - 0.059 12.9 1.3 0.076 12.6 0.3 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KPI45273.1 - 0.07 13.2 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KPI45273.1 - 0.1 12.7 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KPI45273.1 - 0.12 12.2 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.13 KPI45275.1 - 6.9e-08 33.0 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acetyltransf_1 PF00583.25 KPI45276.1 - 2e-13 50.6 0.0 2.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI45276.1 - 2.8e-11 43.4 0.0 6e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI45276.1 - 3.7e-10 40.1 0.0 6.8e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI45276.1 - 1.2e-08 34.8 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KPI45276.1 - 0.00055 20.0 0.0 0.00073 19.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SAS4 PF15460.6 KPI45277.1 - 6.9e-28 96.6 5.3 6.9e-28 96.6 5.3 2.8 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Urb2 PF10441.9 KPI45278.1 - 6e-51 173.3 0.1 1.5e-50 172.0 0.1 1.7 1 0 0 1 1 1 1 Urb2/Npa2 family NACHT PF05729.12 KPI45279.1 - 2e-06 27.8 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cutinase PF01083.22 KPI45279.1 - 0.00017 21.6 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Cutinase AAA_16 PF13191.6 KPI45279.1 - 0.00022 21.7 2.6 0.00098 19.5 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KPI45279.1 - 0.003 17.8 0.2 0.021 15.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.7 KPI45279.1 - 0.0048 17.5 0.1 0.028 15.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KPI45279.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_19 PF13245.6 KPI45279.1 - 0.023 15.0 0.0 0.08 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KPI45279.1 - 0.024 14.8 0.1 0.069 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain LCAT PF02450.15 KPI45279.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KPI45279.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein GlutR_dimer PF00745.20 KPI45279.1 - 0.4 11.2 3.7 17 6.0 0.1 3.0 3 0 0 3 3 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain SVIP PF15811.5 KPI45279.1 - 0.95 10.0 4.1 2.8 8.5 4.1 1.8 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Sulfatase PF00884.23 KPI45280.1 - 1.5e-57 195.4 0.1 2.2e-57 194.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KPI45280.1 - 1.4e-21 76.1 3.7 3.4e-21 74.8 2.4 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KPI45280.1 - 3.1e-10 40.2 0.2 3.8e-09 36.6 0.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KPI45280.1 - 0.0034 18.1 0.1 0.019 15.7 0.1 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KPI45280.1 - 0.0043 16.9 0.0 0.082 12.8 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function DUF229 PF02995.17 KPI45280.1 - 0.0096 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KPI45280.1 - 0.042 12.9 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ribosomal_L35Ae PF01247.18 KPI45281.1 - 4.2e-46 155.0 0.3 4.7e-46 154.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KPI45281.1 - 3.2e-05 24.1 0.0 0.035 14.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Aminotran_1_2 PF00155.21 KPI45282.1 - 9.7e-45 153.3 0.0 1.1e-44 153.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NIR_SIR_ferr PF03460.17 KPI45282.1 - 0.019 14.8 0.0 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Beta_elim_lyase PF01212.21 KPI45282.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 KPI45282.1 - 0.036 12.7 0.0 0.065 11.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Gpr1_Fun34_YaaH PF01184.19 KPI45283.1 - 1.2e-29 103.4 20.2 1.6e-29 103.1 20.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF962 PF06127.11 KPI45285.1 - 1.1e-26 92.8 0.1 1.9e-26 92.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) 2OG-FeII_Oxy PF03171.20 KPI45286.1 - 0.00054 20.4 0.0 0.002 18.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KPI45287.1 - 1.5e-10 41.7 0.0 2.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KPI45287.1 - 4.9e-07 28.9 0.0 0.057 12.2 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Mcp5_PH PF12814.7 KPI45288.1 - 7.4e-44 148.8 0.2 1.4e-43 147.9 0.2 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KPI45288.1 - 0.001 19.6 14.4 0.0023 18.4 14.4 1.5 1 0 0 1 1 1 1 Fez1 DUF724 PF05266.14 KPI45288.1 - 0.034 14.0 4.0 0.069 13.0 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 KPI45288.1 - 0.07 12.8 17.0 0.12 12.0 17.0 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KPI45288.1 - 0.28 11.3 15.7 0.065 13.3 5.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KPI45288.1 - 0.4 10.8 4.7 5.8 7.1 0.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KPI45288.1 - 0.42 10.7 21.6 0.14 12.2 7.8 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 KPI45288.1 - 0.66 9.5 8.3 1.3 8.5 8.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 KPI45288.1 - 1.6 9.2 9.8 4 7.9 9.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3818 PF12825.7 KPI45288.1 - 1.9 7.4 5.6 2.9 6.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF4407 PF14362.6 KPI45288.1 - 1.9 7.7 5.4 3.9 6.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 KPI45288.1 - 2.8 8.6 14.4 0.2 12.3 3.4 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-H2C2_5 PF13909.6 KPI45289.1 - 7e-05 22.5 7.5 7e-05 22.5 7.5 3.4 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KPI45289.1 - 0.0046 17.4 1.6 0.0046 17.4 1.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI45289.1 - 0.037 14.8 18.5 0.22 12.5 1.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KPI45289.1 - 0.11 12.5 4.2 0.31 11.1 4.2 1.7 1 0 0 1 1 1 0 BED zinc finger CSN5_C PF18323.1 KPI45289.1 - 0.68 10.9 3.9 27 5.7 0.0 3.6 3 1 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Sina PF03145.16 KPI45289.1 - 0.69 9.8 12.5 1.4 8.8 12.5 1.4 1 0 0 1 1 1 0 Seven in absentia protein family HMG14_17 PF01101.18 KPI45289.1 - 7.7 7.6 7.3 7.9 7.5 1.3 2.8 2 0 0 2 2 2 0 HMG14 and HMG17 DUF3294 PF07957.11 KPI45290.1 - 0.0042 16.9 1.3 0.0059 16.4 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Glyco_hydro_18 PF00704.28 KPI45291.1 - 3.6e-48 164.9 0.0 4.1e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.8 KPI45291.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) HET PF06985.11 KPI45292.1 - 8.2e-27 94.3 0.6 2.9e-26 92.5 0.6 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dynamin_M PF01031.20 KPI45293.1 - 4.7e-34 117.9 4.9 1.9e-33 115.9 4.9 2.0 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KPI45293.1 - 4.6e-32 111.4 0.6 5.8e-31 107.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KPI45293.1 - 0.00028 20.9 0.4 0.0029 17.7 0.3 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KPI45293.1 - 0.021 14.4 1.2 6.2 6.3 0.1 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 KPI45293.1 - 0.088 13.2 0.7 8.6 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain GED PF02212.18 KPI45293.1 - 0.24 11.6 8.0 0.27 11.4 0.2 3.7 3 1 0 3 3 3 0 Dynamin GTPase effector domain PI-PLC-X PF00388.19 KPI45294.1 - 1.9e-58 196.2 0.0 2.7e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPI45294.1 - 2.5e-40 137.4 0.0 4.9e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PHD PF00628.29 KPI45296.1 - 0.014 15.3 2.7 0.027 14.3 2.7 1.5 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.25 KPI45298.1 - 1.3e-08 34.6 0.0 8.6e-08 31.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain DSBA PF01323.20 KPI45298.1 - 5.3e-07 29.6 1.0 8.8e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Pkinase_Tyr PF07714.17 KPI45298.1 - 0.042 13.1 0.0 0.5 9.6 0.0 2.3 2 1 0 2 2 2 0 Protein tyrosine kinase Peptidase_M16 PF00675.20 KPI45298.1 - 0.9 9.5 4.0 32 4.5 1.8 2.9 2 1 0 2 2 2 0 Insulinase (Peptidase family M16) DUF4972 PF16342.5 KPI45298.1 - 2.2 8.0 4.3 10 5.8 4.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) SHS2_Rpb7-N PF03876.17 KPI45299.1 - 7.5e-13 48.7 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KPI45299.1 - 4.3e-07 30.2 0.0 7.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain G-alpha PF00503.20 KPI45300.1 - 7.4e-20 71.4 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit NLRC4_HD2 PF17776.1 KPI45300.1 - 0.091 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Thioredoxin PF00085.20 KPI45301.1 - 0.0024 17.8 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3807 PF12720.7 KPI45302.1 - 2.4e-27 96.4 5.9 3.3e-27 95.9 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) PBP1_TM PF14812.6 KPI45302.1 - 0.12 12.8 5.0 0.2 12.0 5.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TauD PF02668.16 KPI45303.1 - 1.1e-27 97.6 0.0 1.6e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_4 PF01565.23 KPI45304.1 - 6.3e-22 77.8 3.4 9e-22 77.3 3.4 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI45304.1 - 2.7e-09 37.0 0.0 4.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 KPI45306.1 - 5.2e-33 114.4 1.0 5.2e-33 114.4 1.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Malic_M PF03949.15 KPI45307.1 - 2.3e-89 299.1 0.0 2.8e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KPI45307.1 - 7.2e-58 195.4 0.0 1.2e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GHL10 PF02638.15 KPI45307.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 AA_permease_2 PF13520.6 KPI45308.1 - 3.3e-48 164.6 52.0 2.6e-47 161.6 52.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI45308.1 - 1.2e-25 90.0 34.4 1.2e-25 90.0 34.4 1.8 2 0 0 2 2 2 1 Amino acid permease dCMP_cyt_deam_1 PF00383.23 KPI45309.1 - 8.9e-22 76.9 0.1 1.2e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KPI45309.1 - 1.2e-18 67.2 0.0 1.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KPI45309.1 - 4.1e-05 23.7 1.6 0.26 11.4 0.8 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase APOBEC2 PF18772.1 KPI45309.1 - 0.00033 20.7 0.1 0.012 15.6 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KPI45309.1 - 0.00056 20.0 0.1 0.025 14.6 0.1 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 KPI45309.1 - 0.00065 19.8 0.0 0.0042 17.2 0.0 2.0 1 1 2 3 3 3 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 KPI45309.1 - 0.002 18.0 0.1 0.044 13.7 0.1 2.0 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 KPI45309.1 - 0.0039 17.3 0.0 0.035 14.2 0.0 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 XOO_2897-deam PF14440.6 KPI45309.1 - 0.14 12.3 0.1 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase MFS_1 PF07690.16 KPI45310.1 - 2.7e-38 131.8 28.2 3.7e-38 131.4 28.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KPI45310.1 - 0.013 15.2 0.1 0.013 15.2 0.1 3.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) Complex1_49kDa PF00346.19 KPI45311.1 - 1.9e-120 401.0 0.0 3.5e-120 400.2 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pkinase PF00069.25 KPI45311.1 - 2.4e-51 174.6 0.5 3.6e-28 98.7 0.3 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45311.1 - 1.9e-25 89.6 0.0 3.1e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase NiFeSe_Hases PF00374.19 KPI45311.1 - 0.0071 15.3 0.1 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 Nickel-dependent hydrogenase DUF1752 PF08550.10 KPI45312.1 - 6.2e-06 26.0 7.4 1.2e-05 25.0 7.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ovate PF04844.13 KPI45313.1 - 0.091 12.8 0.1 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional repressor, ovate DUF2259 PF10016.9 KPI45315.1 - 0.11 12.5 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) DUF5401 PF17380.2 KPI45315.1 - 4.1 5.4 13.3 5.8 4.9 13.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Glyco_transf_34 PF05637.12 KPI45316.1 - 7.9e-64 215.6 0.4 1.1e-63 215.2 0.4 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family LMBR1 PF04791.16 KPI45317.1 - 3.9e-17 62.4 4.1 3.9e-17 62.4 4.1 2.4 2 1 1 3 3 3 2 LMBR1-like membrane protein Wzy_C PF04932.15 KPI45317.1 - 0.043 13.4 0.0 0.043 13.4 0.0 4.5 3 1 1 4 4 4 0 O-Antigen ligase DUF2457 PF10446.9 KPI45318.1 - 1.9e-130 436.1 38.7 1.9e-130 436.1 38.7 2.8 2 2 1 3 3 3 1 Protein of unknown function (DUF2457) ubiquitin PF00240.23 KPI45319.1 - 3.9e-25 87.4 0.1 4.3e-25 87.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KPI45319.1 - 1.7e-14 53.4 0.1 1.8e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KPI45319.1 - 0.00043 20.7 0.0 0.0012 19.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KPI45319.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KPI45319.1 - 0.084 13.0 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Csm1_N PF18504.1 KPI45320.1 - 0.0095 16.3 1.5 0.0095 16.3 1.5 6.4 5 2 3 8 8 8 1 Csm1 N-terminal domain MSL1_dimer PF16801.5 KPI45320.1 - 6.4 6.6 6.4 0.71 9.7 0.2 2.6 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 Glyco_hydro_16 PF00722.21 KPI45321.1 - 0.0001 21.8 0.4 0.00036 20.0 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 PI-PLC-X PF00388.19 KPI45322.1 - 1.9e-45 154.0 0.0 3.1e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KPI45322.1 - 1e-36 125.8 0.0 2.1e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KPI45322.1 - 0.025 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 C2 domain FerI PF08151.12 KPI45322.1 - 0.38 10.9 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 FerI (NUC094) domain Kinesin PF00225.23 KPI45323.1 - 1.6e-110 369.1 0.3 2.7e-110 368.4 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 KPI45323.1 - 4.3e-39 134.5 8.5 2.4e-31 109.3 0.4 3.3 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KPI45323.1 - 3e-24 85.7 0.0 8.2e-24 84.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 KPI45323.1 - 2.2e-05 24.7 0.1 0.00017 21.9 0.0 2.5 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KPI45323.1 - 0.00012 22.4 1.2 0.00037 20.9 1.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 KPI45323.1 - 0.00021 21.6 0.0 0.00069 19.9 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Sybindin PF04099.12 KPI45324.1 - 5.6e-25 87.9 0.0 6.9e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KPI45324.1 - 0.026 14.7 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region MMS19_N PF14500.6 KPI45325.1 - 1.2e-89 300.3 0.1 3.1e-89 299.0 0.0 1.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KPI45325.1 - 0.00037 20.8 4.2 0.15 12.5 0.2 4.1 4 0 0 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 KPI45325.1 - 0.0029 16.3 0.9 0.14 10.7 0.2 2.9 3 0 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 KPI45325.1 - 0.0042 17.2 1.3 0.3 11.1 0.1 3.7 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KPI45325.1 - 0.058 14.0 0.4 2.7 8.6 0.1 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KPI45325.1 - 0.08 13.2 3.8 1.2 9.6 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat IU_nuc_hydro PF01156.19 KPI45326.1 - 6.3e-74 249.3 0.0 7.6e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase 3Beta_HSD PF01073.19 KPI45327.1 - 1.8e-42 145.2 0.0 2.2e-38 131.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPI45327.1 - 9.4e-24 84.2 0.0 8.4e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI45327.1 - 1.7e-16 60.5 0.2 7.1e-12 45.4 0.0 3.1 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KPI45327.1 - 5.7e-13 48.6 0.1 2.4e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KPI45327.1 - 3.2e-11 42.9 0.4 9.9e-11 41.3 0.2 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KPI45327.1 - 0.00021 20.5 0.2 0.013 14.7 0.1 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KPI45327.1 - 0.00043 20.2 0.0 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KPI45327.1 - 0.0021 18.0 0.1 0.05 13.5 0.1 2.7 1 1 0 1 1 1 1 KR domain Gly_transf_sug PF04488.15 KPI45328.1 - 3.8e-07 30.7 0.0 7.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ELMO_CED12 PF04727.13 KPI45329.1 - 2.7e-41 141.6 0.1 4.6e-41 140.9 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KPI45329.1 - 1.2e-25 90.6 0.0 1.2e-24 87.3 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 KPI45329.1 - 9.5e-15 54.9 0.0 2.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ADH_N PF08240.12 KPI45330.1 - 2.3e-24 85.3 3.7 3.6e-24 84.8 3.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI45330.1 - 8.5e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI45330.1 - 0.00022 22.3 0.0 0.00035 21.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_4 PF01565.23 KPI45332.1 - 7.1e-24 84.1 2.6 1.2e-23 83.4 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KPI45332.1 - 7.5e-08 32.3 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KPI45332.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4585 PF15232.6 KPI45334.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Flot PF15975.5 KPI45335.1 - 0.36 11.0 5.3 0.093 12.9 0.9 2.3 2 0 0 2 2 2 0 Flotillin Nbl1_Borealin_N PF10444.9 KPI45336.1 - 3.6e-20 71.3 3.7 5.6e-20 70.7 3.7 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal zf-C2H2 PF00096.26 KPI45337.1 - 0.008 16.6 22.4 2.4 8.8 0.4 5.1 4 1 0 4 4 4 2 Zinc finger, C2H2 type CNDH2_C PF16858.5 KPI45337.1 - 0.099 12.5 3.5 0.17 11.7 3.5 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-C2H2_6 PF13912.6 KPI45337.1 - 0.23 11.5 3.1 7 6.8 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KPI45337.1 - 1.3 9.5 5.7 3.6 8.1 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ADK_lid PF05191.14 KPI45337.1 - 1.3 9.1 5.2 3.6 7.6 1.7 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_4 PF13894.6 KPI45337.1 - 1.9 9.5 21.6 0.81 10.7 0.3 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger FYDLN_acid PF09538.10 KPI45337.1 - 3 8.6 14.2 8.4 7.1 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_jaz PF12171.8 KPI45337.1 - 3.8 7.9 7.9 8.3 6.8 1.4 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zip PF02535.22 KPI45338.1 - 7.6e-18 64.8 1.1 9.6e-18 64.5 1.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HLH PF00010.26 KPI45339.1 - 6e-14 51.7 0.5 6e-14 51.7 0.5 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Prefoldin_2 PF01920.20 KPI45339.1 - 0.0072 16.3 2.8 0.014 15.4 2.8 1.5 1 0 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 KPI45339.1 - 0.0088 16.4 1.8 0.014 15.8 1.1 1.7 2 0 0 2 2 1 1 Flagella accessory protein C (FlaC) Macoilin PF09726.9 KPI45339.1 - 0.015 13.9 5.3 0.017 13.7 5.3 1.1 1 0 0 1 1 1 0 Macoilin family DLIC PF05783.11 KPI45339.1 - 0.094 11.5 0.8 0.14 11.0 0.2 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) CortBP2 PF09727.9 KPI45339.1 - 0.13 12.2 6.6 0.18 11.7 6.6 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 Exonuc_VII_L PF02601.15 KPI45339.1 - 0.18 11.4 3.5 0.21 11.1 3.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KPI45339.1 - 0.46 8.3 3.3 0.61 7.9 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 KPI45339.1 - 0.58 10.2 11.0 0.38 10.8 8.8 1.9 2 1 0 2 2 2 0 FlxA-like protein BST2 PF16716.5 KPI45339.1 - 0.66 10.6 6.2 1.3 9.6 6.2 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DHR10 PF18595.1 KPI45339.1 - 1.1 9.4 10.4 1.5 8.9 9.6 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain zf-C4H2 PF10146.9 KPI45339.1 - 1.1 9.5 10.1 0.27 11.5 6.7 1.7 1 1 1 2 2 2 0 Zinc finger-containing protein Neur_chan_memb PF02932.16 KPI45339.1 - 1.2 9.2 3.8 2.1 8.3 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tox-ODYAM1 PF15642.6 KPI45339.1 - 1.4 7.8 4.0 1.9 7.4 4.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus LMBR1 PF04791.16 KPI45339.1 - 4 6.2 4.5 4.8 6.0 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LSM PF01423.22 KPI45340.1 - 2.3e-15 56.0 0.5 3.8e-15 55.3 0.5 1.4 1 0 0 1 1 1 1 LSM domain PCI PF01399.27 KPI45341.1 - 1.5e-09 38.3 6.7 1.6e-09 38.2 0.0 3.4 3 0 0 3 3 3 1 PCI domain VWA_3 PF13768.6 KPI45342.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Helitron_like_N PF14214.6 KPI45342.1 - 0.08 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Aminotran_1_2 PF00155.21 KPI45343.1 - 6.4e-48 163.8 0.0 7.8e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Kdo_hydroxy PF11004.8 KPI45343.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Sec1 PF00995.23 KPI45344.1 - 8.1e-106 355.5 0.0 7.2e-99 332.6 0.0 2.0 1 1 1 2 2 2 2 Sec1 family PGP_phosphatase PF09419.10 KPI45345.1 - 0.0039 16.8 0.2 0.0082 15.8 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase ABC_trans_N PF14510.6 KPI45345.1 - 0.025 15.2 1.1 8.9 7.0 0.0 3.6 3 0 0 3 3 3 0 ABC-transporter N-terminal Pkinase PF00069.25 KPI45347.1 - 9.1e-56 189.1 0.1 1.2e-54 185.4 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45347.1 - 7.8e-15 54.9 0.1 3.1e-14 52.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI45347.1 - 9.8e-07 28.9 0.0 9.6e-05 22.4 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KPI45347.1 - 0.0029 17.2 0.1 0.0064 16.1 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KPI45347.1 - 0.0046 15.8 0.1 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KPI45347.1 - 0.012 15.0 0.2 0.02 14.2 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_6 PF08030.12 KPI45348.1 - 3.1e-33 115.1 0.0 5.5e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KPI45348.1 - 8.3e-22 77.3 0.0 1.8e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KPI45348.1 - 2.8e-19 69.5 10.6 3.2e-18 66.0 6.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KPI45348.1 - 0.072 13.7 0.0 0.7 10.6 0.0 2.5 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KPI45348.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Nnf1 PF03980.14 KPI45349.1 - 2.3e-28 98.8 4.4 3.5e-28 98.2 4.4 1.3 1 0 0 1 1 1 1 Nnf1 SHE3 PF17078.5 KPI45349.1 - 0.0066 16.2 0.3 0.086 12.5 0.3 2.0 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 KPI45349.1 - 0.018 15.2 4.0 0.034 14.2 4.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-B_box PF00643.24 KPI45350.1 - 0.037 14.2 1.3 0.055 13.6 1.3 1.2 1 0 0 1 1 1 0 B-box zinc finger MFS_1 PF07690.16 KPI45351.1 - 1.3e-25 90.1 12.1 1.7e-25 89.7 12.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RCR PF12273.8 KPI45352.1 - 2e-12 47.8 4.5 7.9e-12 45.9 4.5 2.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red zf-rbx1 PF12678.7 KPI45352.1 - 9.7e-10 38.6 3.7 1.7e-09 37.8 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KPI45352.1 - 9.5e-08 32.2 8.1 3.6e-07 30.4 8.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPI45352.1 - 2e-06 27.6 3.6 3.4e-06 26.8 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KPI45352.1 - 0.00012 22.0 0.9 0.00036 20.5 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KPI45352.1 - 0.00015 21.7 4.5 0.00029 20.8 4.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KPI45352.1 - 0.00018 21.1 0.4 0.00037 20.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KPI45352.1 - 0.00042 20.1 3.6 0.00042 20.1 3.6 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI45352.1 - 0.00068 19.4 6.3 0.0013 18.5 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI45352.1 - 0.00073 19.5 5.2 0.0033 17.3 5.4 1.9 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPI45352.1 - 0.0049 16.7 3.8 0.012 15.5 3.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KPI45352.1 - 0.047 13.4 1.5 0.49 10.2 0.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger Alanine_zipper PF11839.8 KPI45352.1 - 0.26 11.7 6.4 0.63 10.4 6.4 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein zf-C3HC4_4 PF15227.6 KPI45352.1 - 0.86 9.8 4.8 0.21 11.8 1.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KPI45352.1 - 1.7 8.5 3.7 0.93 9.3 1.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2897 PF11446.8 KPI45352.1 - 1.8 8.5 3.1 3.7 7.5 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RTC4 PF14474.6 KPI45353.1 - 9.5e-27 93.6 0.0 1.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain HeLo PF14479.6 KPI45354.1 - 3e-10 40.3 0.1 5.1e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF1993 PF09351.10 KPI45355.1 - 2.4 8.3 5.4 2.1 8.5 3.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) MMR_HSR1 PF01926.23 KPI45356.1 - 7e-10 39.0 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KPI45356.1 - 1.8e-07 30.7 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KPI45356.1 - 0.00095 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Septin Roc PF08477.13 KPI45356.1 - 0.0013 18.9 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KPI45356.1 - 0.0022 18.6 0.0 0.0042 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 KPI45356.1 - 0.0033 17.1 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.18 KPI45356.1 - 0.0053 16.2 1.0 1.7 7.9 0.0 2.6 1 1 1 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KPI45356.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KPI45356.1 - 0.024 14.2 0.2 0.045 13.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KPI45356.1 - 0.025 15.1 0.0 0.049 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KPI45356.1 - 0.027 14.4 0.4 0.046 13.6 0.4 1.3 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 KPI45356.1 - 0.034 13.8 0.4 0.61 9.7 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 KPI45356.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KPI45356.1 - 0.077 12.8 0.5 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KPI45356.1 - 0.11 12.9 0.1 0.33 11.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 KPI45356.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KPI45356.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 KPI45356.1 - 0.16 11.7 0.5 0.28 10.9 0.5 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KPI45356.1 - 0.16 11.0 0.6 0.31 10.0 0.6 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KPI45356.1 - 0.28 11.2 0.9 11 6.0 0.7 2.4 1 1 1 2 2 2 0 Dynamin family DUF87 PF01935.17 KPI45356.1 - 0.3 11.2 1.0 0.58 10.2 1.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 KPI45356.1 - 0.38 11.0 2.6 0.64 10.2 1.0 2.2 2 0 0 2 2 2 0 AAA domain Ubiq_cyt_C_chap PF03981.12 KPI45357.1 - 3e-29 101.9 0.2 5.4e-29 101.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone zf-PHD-like PF15446.6 KPI45358.1 - 0.015 14.9 1.3 0.025 14.2 1.3 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Malic_M PF03949.15 KPI45360.1 - 4.2e-73 245.8 0.1 1.3e-70 237.6 0.1 2.2 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KPI45360.1 - 8.1e-63 211.5 0.0 1.3e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Baculo_PEP_C PF04513.12 KPI45362.1 - 0.0043 17.1 1.0 0.0085 16.1 0.1 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S41 PF03572.18 KPI45362.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S41 SPATIAL PF15256.6 KPI45363.1 - 0.14 12.5 2.2 0.34 11.2 2.2 1.6 1 0 0 1 1 1 0 SPATIAL DUF1664 PF07889.12 KPI45364.1 - 0.14 12.2 0.5 0.35 10.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KPI45364.1 - 2.9 8.1 5.5 3.1 8.0 1.7 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Sds3 PF08598.11 KPI45365.1 - 1.3e-17 64.5 1.4 1.3e-17 64.5 1.4 2.5 2 1 0 2 2 2 1 Sds3-like Linker_histone PF00538.19 KPI45366.1 - 8.6e-31 106.1 0.4 8.6e-31 106.1 0.4 2.4 2 0 0 2 2 2 1 linker histone H1 and H5 family Toxin_trans PF07952.12 KPI45366.1 - 0.057 12.5 0.3 0.08 12.0 0.3 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Thioredoxin PF00085.20 KPI45367.1 - 2e-31 108.0 0.1 2.3e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KPI45367.1 - 7.4e-09 35.8 0.0 9.6e-05 22.4 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KPI45367.1 - 1.8e-07 31.6 0.1 0.032 14.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain TraF PF13728.6 KPI45367.1 - 9.1e-06 25.7 3.2 0.0021 17.9 0.0 3.2 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KPI45367.1 - 0.00015 22.1 0.1 2.3 8.6 0.0 4.1 3 1 1 4 4 4 1 Thioredoxin-like QSOX_Trx1 PF18108.1 KPI45367.1 - 0.00028 21.0 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 QSOX Trx-like domain OST3_OST6 PF04756.13 KPI45367.1 - 0.00029 20.3 0.0 0.007 15.8 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KPI45367.1 - 0.0035 17.3 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 KPI45367.1 - 0.0049 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KPI45367.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like ERp29_N PF07912.13 KPI45367.1 - 0.043 14.0 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 ERp29, N-terminal domain HyaE PF07449.11 KPI45367.1 - 0.091 12.7 0.0 0.82 9.7 0.0 2.5 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE BTB PF00651.31 KPI45368.1 - 0.0082 16.4 0.0 0.34 11.1 0.0 2.7 2 0 0 2 2 2 1 BTB/POZ domain CBFB_NFYA PF02045.15 KPI45369.1 - 5.8e-29 100.5 4.6 1.2e-28 99.5 4.6 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KPI45369.1 - 0.018 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Pol_alpha_B_N PF08418.10 KPI45369.1 - 1.7 8.6 8.9 0.29 11.1 5.0 1.6 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Pal1 PF08316.11 KPI45370.1 - 1.3e-05 25.9 0.1 2.3e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 Pal1 cell morphology protein PEP_mutase PF13714.6 KPI45371.1 - 2.5e-49 167.9 0.1 3.2e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase EF-hand_6 PF13405.6 KPI45372.1 - 1.9e-09 36.7 0.0 2.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KPI45372.1 - 4.9e-08 32.0 0.0 9.2e-05 21.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KPI45372.1 - 5.2e-07 30.0 0.1 0.00012 22.4 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KPI45372.1 - 6.6e-07 28.6 1.0 0.00016 21.0 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KPI45372.1 - 0.00026 20.8 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KPI45372.1 - 0.0082 16.4 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain PX PF00787.24 KPI45373.1 - 7.5e-20 71.0 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 PX domain SCIMP PF15050.6 KPI45373.1 - 0.09 13.2 0.1 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 SCIMP protein AA_permease_2 PF13520.6 KPI45374.1 - 6.2e-33 114.2 32.0 7.5e-33 114.0 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI45374.1 - 4e-12 45.5 22.9 5.5e-12 45.0 22.9 1.1 1 0 0 1 1 1 1 Amino acid permease 5TM-5TMR_LYT PF07694.12 KPI45374.1 - 1.1 8.8 12.6 1.3 8.5 10.0 2.5 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Glycos_transf_1 PF00534.20 KPI45376.1 - 3.6e-36 124.3 0.0 8.1e-36 123.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPI45376.1 - 5.8e-32 110.9 0.0 1.1e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPI45376.1 - 2.5e-15 57.3 0.1 8.3e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KPI45376.1 - 2.2e-11 44.0 0.3 1.3e-10 41.5 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KPI45376.1 - 3.2e-09 37.1 0.0 7.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Esterase PF00756.20 KPI45377.1 - 5.6e-46 157.2 0.0 7.5e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KPI45377.1 - 5.7e-07 29.3 0.0 5.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.12 KPI45377.1 - 7.6e-05 21.5 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KPI45377.1 - 7.7e-05 22.3 0.1 0.00022 20.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KPI45377.1 - 0.0023 16.9 0.0 0.0065 15.4 0.0 1.7 1 1 1 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KPI45377.1 - 0.0034 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KPI45377.1 - 0.019 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 KPI45377.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KPI45377.1 - 0.072 12.8 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF1772 PF08592.11 KPI45378.1 - 3e-17 63.2 1.0 3.6e-17 63.0 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Methyltransf_11 PF08241.12 KPI45379.1 - 2.6e-12 47.2 0.0 5.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI45379.1 - 1e-11 45.4 0.0 3.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45379.1 - 6e-09 36.5 0.0 1.4e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45379.1 - 1.3e-08 34.8 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI45379.1 - 8e-08 32.3 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI45379.1 - 0.15 11.6 0.0 1.4 8.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase small domain Vps8 PF12816.7 KPI45380.1 - 1.3e-57 194.5 0.3 3.5e-57 193.1 0.3 1.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KPI45380.1 - 2.9e-05 24.0 0.3 0.014 15.3 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS RNase_T PF00929.24 KPI45381.1 - 3.3e-08 34.2 0.0 7.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease A_deaminase PF00962.22 KPI45382.1 - 4.2e-118 394.4 0.0 6.3e-118 393.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans PF04082.18 KPI45383.1 - 0.00013 21.1 0.1 0.00036 19.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KPI45384.1 - 3.3e-68 230.5 0.0 4.1e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yip1 PF04893.17 KPI45385.1 - 0.0058 16.4 0.3 0.0072 16.1 0.3 1.1 1 0 0 1 1 1 1 Yip1 domain DUF4834 PF16118.5 KPI45385.1 - 0.045 14.7 0.2 0.082 13.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ribonuc_L-PSP PF01042.21 KPI45387.1 - 6e-17 61.8 0.0 7.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.11 KPI45387.1 - 0.052 13.5 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 NOGCT (NUC087) domain adh_short PF00106.25 KPI45388.1 - 5.1e-15 55.5 0.0 1.7e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KPI45388.1 - 4.5e-05 23.4 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KPI45388.1 - 0.00063 19.2 0.1 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI45388.1 - 0.021 14.3 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UPF0183 PF03676.14 KPI45389.1 - 9.2e-53 179.9 0.0 1.4e-35 123.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) CorA PF01544.18 KPI45390.1 - 0.0014 18.0 10.5 0.014 14.7 10.5 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_trans_1_4 PF13692.6 KPI45391.1 - 9.8e-12 45.5 0.0 2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KPI45391.1 - 1.7e-11 44.0 0.0 3.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KPI45391.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Abhydrolase_6 PF12697.7 KPI45393.1 - 9.2e-10 39.5 0.1 1.1e-09 39.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KPI45393.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 KPI45393.1 - 0.036 13.9 0.9 0.67 9.7 0.2 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 KPI45393.1 - 0.09 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KPI45393.1 - 0.11 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KPI45393.1 - 0.12 12.1 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KPI45393.1 - 0.18 11.4 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DLH PF01738.18 KPI45393.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.27 KPI45394.1 - 3.8e-42 144.0 0.0 6.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KPI45394.1 - 6.6e-29 100.5 0.1 2.5e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KPI45394.1 - 0.00016 21.7 0.1 0.0012 18.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KPI45394.1 - 0.00092 19.5 0.2 0.0022 18.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.20 KPI45394.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit TonB_N PF16031.5 KPI45394.1 - 2 8.9 27.7 4.1 7.9 27.7 1.4 1 0 0 1 1 1 0 TonB polyproline region KAR9 PF08580.10 KPI45394.1 - 2.6 6.5 7.5 3.6 6.0 7.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 NAD_Gly3P_dh_N PF01210.23 KPI45395.1 - 5.1e-46 156.5 0.1 1.4e-45 155.1 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KPI45395.1 - 5.7e-43 146.6 0.2 1.1e-42 145.7 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus MFS_1 PF07690.16 KPI45398.1 - 4.2e-27 95.0 25.5 4.2e-27 95.0 25.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily NMT_C PF02799.15 KPI45399.1 - 8.7e-84 280.2 0.0 1.3e-83 279.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KPI45399.1 - 3.7e-72 241.4 0.0 2.7e-71 238.6 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KPI45399.1 - 0.00023 21.3 0.0 0.046 13.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain EF-hand_8 PF13833.6 KPI45399.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Acetyltransf_1 PF00583.25 KPI45399.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ntox34 PF15606.6 KPI45399.1 - 0.087 13.0 0.1 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial toxin 34 FR47 PF08445.10 KPI45399.1 - 0.14 12.2 0.0 0.64 10.0 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Glyco_transf_90 PF05686.12 KPI45400.1 - 1.5e-14 53.8 0.0 1.3e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 AA_permease_2 PF13520.6 KPI45401.1 - 1.4e-35 123.0 13.8 1e-18 67.4 2.3 2.9 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KPI45401.1 - 2.4 6.6 20.2 0.0064 15.1 9.7 2.2 2 1 0 2 2 2 0 Amino acid permease MFS_1 PF07690.16 KPI45402.1 - 1.5e-31 109.6 15.1 1.5e-31 109.6 15.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DPBB_1 PF03330.18 KPI45403.1 - 2.5e-08 34.1 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KPI45403.1 - 0.09 12.6 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Barwin family AcrZ PF10766.9 KPI45403.1 - 0.2 11.3 1.3 0.31 10.6 1.3 1.2 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Adaptin_N PF01602.20 KPI45404.1 - 1.1e-84 284.9 0.4 1.5e-84 284.5 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KPI45404.1 - 4.3e-09 36.6 1.8 7.6e-06 26.1 0.0 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KPI45404.1 - 6.6e-05 23.3 6.5 0.19 12.3 0.1 4.8 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 KPI45404.1 - 0.0009 19.6 2.7 0.48 10.9 0.1 4.4 3 1 1 4 4 4 1 HEAT repeats AP3D1 PF06375.11 KPI45404.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 3.2 2 1 1 3 3 3 1 AP-3 complex subunit delta-1 HEAT PF02985.22 KPI45404.1 - 0.044 14.0 9.4 3.2 8.2 0.0 6.0 8 0 0 8 8 8 0 HEAT repeat Rrn6 PF10214.9 KPI45404.1 - 4.5 5.7 9.1 7.9 4.8 9.1 1.5 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RTA1 PF04479.13 KPI45405.1 - 2.1e-71 239.8 11.5 2.1e-71 239.8 11.5 1.8 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.17 KPI45405.1 - 0.027 14.4 0.6 0.027 14.4 0.6 2.0 2 0 0 2 2 2 0 Caveolin DUF4079 PF13301.6 KPI45405.1 - 0.038 14.1 1.0 0.067 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) SMK-1 PF04802.15 KPI45406.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 F-box-like PF12937.7 KPI45406.1 - 0.097 12.6 0.2 0.31 11.0 0.2 1.9 1 0 0 1 1 1 0 F-box-like DUF2353 PF09789.9 KPI45406.1 - 0.37 10.1 1.8 0.6 9.4 1.8 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) MFS_1 PF07690.16 KPI45407.1 - 6.4e-19 68.1 21.1 6.4e-19 68.1 21.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_U4 PF03419.13 KPI45407.1 - 0.0013 18.0 2.5 0.0014 18.0 0.4 1.9 1 1 1 2 2 2 1 Sporulation factor SpoIIGA ArfGap PF01412.18 KPI45408.1 - 2.3e-32 111.5 0.4 8.1e-32 109.7 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KPI45408.1 - 4.8e-20 72.3 15.2 8.2e-20 71.5 15.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KPI45408.1 - 4.8e-12 46.3 0.3 1.3e-11 45.0 0.3 1.8 1 0 0 1 1 1 1 PH domain Prenyltrans PF00432.21 KPI45409.1 - 1.8e-51 171.6 6.6 1.6e-11 43.7 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KPI45409.1 - 1.8e-05 24.0 0.0 0.018 14.1 0.0 2.9 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KPI45409.1 - 2.5e-05 23.5 0.0 0.084 12.0 0.0 3.4 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain ABC2_membrane PF01061.24 KPI45410.1 - 1.7e-36 125.6 23.4 2.8e-36 124.9 23.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KPI45410.1 - 3.4e-06 26.4 25.1 3.4e-06 26.4 25.1 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KPI45410.1 - 6.8 5.9 18.6 89 2.2 18.6 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4448 PF14610.6 KPI45411.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4215 PF13948.6 KPI45411.1 - 0.13 12.7 2.3 0.34 11.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Cation_efflux PF01545.21 KPI45413.1 - 3.1e-23 82.5 5.0 3.9e-23 82.2 5.0 1.1 1 0 0 1 1 1 1 Cation efflux family Rab5ip PF07019.12 KPI45413.1 - 0.63 10.7 3.6 0.17 12.5 0.3 1.8 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) MFS_1 PF07690.16 KPI45414.1 - 2.5e-38 131.9 27.9 3.2e-38 131.6 27.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI45414.1 - 6.7e-07 28.5 10.7 6.7e-07 28.5 10.7 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KPI45414.1 - 7.3e-05 21.4 4.7 0.00011 20.7 4.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFIIS_C PF01096.18 KPI45415.1 - 2.3e-12 46.6 2.2 2.3e-12 46.6 2.2 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KPI45415.1 - 5.1e-05 23.0 1.7 5.1e-05 23.0 1.7 2.5 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KPI45415.1 - 0.00011 22.2 6.6 0.016 15.3 1.2 2.4 2 0 0 2 2 2 2 Double zinc ribbon Rpr2 PF04032.16 KPI45415.1 - 0.0014 18.9 6.1 0.73 10.2 3.2 2.7 1 1 1 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain Churchill PF06573.11 KPI45415.1 - 0.0098 16.2 8.3 0.062 13.6 0.4 2.5 1 1 1 2 2 2 1 Churchill protein DUF2387 PF09526.10 KPI45415.1 - 0.011 15.8 6.0 0.26 11.4 0.4 2.6 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) HNH_5 PF14279.6 KPI45415.1 - 0.024 14.5 4.4 4.9 7.1 0.2 3.4 3 1 0 3 3 3 0 HNH endonuclease A2L_zn_ribbon PF08792.10 KPI45415.1 - 0.099 12.4 8.2 1.9 8.3 0.2 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain RNHCP PF12647.7 KPI45415.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.7 2 1 1 3 3 3 0 RNHCP domain Zn_ribbon_17 PF17120.5 KPI45415.1 - 0.56 9.9 8.1 3.6 7.3 0.6 3.1 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type GFA PF04828.14 KPI45415.1 - 0.97 9.8 9.6 1.2 9.5 0.0 2.7 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Paired_CXXCH_1 PF09699.10 KPI45415.1 - 1.5 8.6 9.8 4.9 7.0 0.2 3.3 4 0 0 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) Nudix_N_2 PF14803.6 KPI45415.1 - 1.5 8.8 12.8 19 5.3 0.1 3.8 3 1 0 3 3 3 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 KPI45415.1 - 6.4 7.0 16.3 2.9 8.1 0.2 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zf-P11 PF03854.14 KPI45415.1 - 7.4 6.3 11.0 5 6.9 0.3 3.4 4 0 0 4 4 4 0 P-11 zinc finger Lar_restr_allev PF14354.6 KPI45415.1 - 8.7 6.8 9.0 0.89 10.0 0.8 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar Kinesin PF00225.23 KPI45416.1 - 1e-72 244.9 0.1 3.4e-67 226.7 0.0 3.1 1 1 2 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KPI45416.1 - 7.2e-07 29.3 0.0 0.00025 21.0 0.0 3.0 2 1 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KPI45416.1 - 0.016 15.1 6.5 0.078 12.8 0.9 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KPI45416.1 - 0.028 13.8 16.9 0.079 12.3 5.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KPI45416.1 - 0.065 13.3 14.9 0.3 11.1 1.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KPI45416.1 - 0.094 13.1 16.2 3.8 7.9 6.4 3.9 3 0 0 3 3 3 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 KPI45416.1 - 0.23 11.7 17.6 0.22 11.7 7.6 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 KPI45416.1 - 0.52 10.7 17.0 2.2 8.7 4.0 2.5 2 0 0 2 2 2 0 Fez1 DUF2046 PF09755.9 KPI45416.1 - 0.57 9.4 16.7 0.068 12.4 7.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Spc7 PF08317.11 KPI45416.1 - 0.63 8.9 16.3 0.33 9.8 7.1 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 KPI45416.1 - 4.1 7.9 10.6 25 5.4 5.0 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF3138 PF11336.8 KPI45416.1 - 4.2 5.9 6.3 0.26 9.9 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) DUF4200 PF13863.6 KPI45416.1 - 4.6 7.7 19.0 0.86 10.0 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Pkinase PF00069.25 KPI45417.1 - 1.5e-69 234.3 0.0 1.9e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45417.1 - 9.3e-31 107.0 0.0 1.6e-30 106.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KPI45417.1 - 0.00016 21.1 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KPI45417.1 - 0.0012 17.9 0.1 0.014 14.3 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KPI45417.1 - 0.006 16.5 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KPI45417.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 PIP5K PF01504.18 KPI45419.1 - 7.9e-33 113.8 0.0 1.4e-26 93.3 0.6 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KPI45419.1 - 3.5e-29 101.8 0.1 5.8e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF789 PF05623.12 KPI45419.1 - 0.099 12.3 2.6 1.9 8.1 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF789) Proteasome PF00227.26 KPI45420.1 - 8.5e-48 162.4 0.1 1.1e-47 162.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cellulase PF00150.18 KPI45421.1 - 5.8e-32 111.2 1.0 5.8e-32 111.2 1.0 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KPI45421.1 - 0.0042 16.5 0.1 0.34 10.2 0.1 2.5 1 1 0 1 1 1 1 Beta-galactosidase Transp_cyt_pur PF02133.15 KPI45422.1 - 6.1e-101 338.4 39.0 7.7e-101 338.0 39.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ubie_methyltran PF01209.18 KPI45423.1 - 1.3e-81 273.4 0.0 1.6e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KPI45423.1 - 1.3e-17 64.3 0.0 3.2e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45423.1 - 7.3e-16 58.3 0.0 2.1e-15 56.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI45423.1 - 3.2e-15 56.5 0.0 2.2e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45423.1 - 3.2e-11 43.9 0.0 5.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI45423.1 - 8.9e-08 32.1 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KPI45423.1 - 0.064 13.3 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Na_H_Exchanger PF00999.21 KPI45424.1 - 1.3e-34 119.6 16.8 2e-34 119.0 16.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3382 PF11862.8 KPI45424.1 - 0.096 13.0 2.7 0.47 10.8 2.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) YrhC PF14143.6 KPI45424.1 - 0.15 12.2 0.0 0.15 12.2 0.0 4.4 5 1 0 5 5 5 0 YrhC-like protein LD_cluster2 PF18163.1 KPI45425.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster2 adh_short PF00106.25 KPI45426.1 - 7.8e-42 142.9 0.1 8.8e-42 142.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45426.1 - 5.8e-40 137.3 0.0 6.8e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45426.1 - 2.9e-13 50.1 0.0 4.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 KPI45426.1 - 0.017 14.4 0.6 0.063 12.6 0.1 1.8 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HATPase_c PF02518.26 KPI45426.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2235 PF09994.9 KPI45427.1 - 2.3e-36 125.6 0.0 4.1e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 KPI45427.1 - 6.2e-07 29.5 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI45427.1 - 0.00016 21.6 1.0 0.00069 19.6 0.0 2.3 2 1 1 3 3 3 1 RsgA GTPase Septin PF00735.18 KPI45427.1 - 0.00028 20.3 0.2 0.0012 18.2 0.0 1.9 2 0 0 2 2 2 1 Septin Roc PF08477.13 KPI45427.1 - 0.0044 17.2 0.7 0.094 12.9 0.6 2.7 2 1 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KPI45427.1 - 0.0072 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Gtr1_RagA PF04670.12 KPI45427.1 - 0.0089 15.4 0.1 0.021 14.2 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KPI45427.1 - 0.009 15.5 0.3 0.93 8.9 0.1 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 KPI45427.1 - 0.03 14.8 0.1 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 KPI45427.1 - 0.043 14.1 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KPI45427.1 - 0.05 14.0 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 KPI45427.1 - 0.063 13.3 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 KPI45427.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KPI45427.1 - 0.088 12.3 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KPI45427.1 - 0.093 12.5 2.6 4.2 7.1 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KPI45427.1 - 0.1 12.5 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 KPI45427.1 - 0.13 12.8 0.2 0.34 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain BMP2K_C PF15282.6 KPI45427.1 - 0.2 11.5 2.5 0.22 11.3 1.3 1.6 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus PAN_1 PF00024.26 KPI45428.1 - 8.3e-06 25.7 5.3 0.11 12.4 0.8 3.4 3 0 0 3 3 3 2 PAN domain SKG6 PF08693.10 KPI45428.1 - 0.0014 18.0 0.3 0.0027 17.1 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 KPI45428.1 - 0.0093 15.7 0.3 0.019 14.7 0.3 1.4 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like DUF5374 PF17344.2 KPI45428.1 - 0.1 12.5 4.9 0.58 10.1 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5374) adh_short PF00106.25 KPI45429.1 - 1.6e-24 86.4 0.1 2.5e-20 72.8 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45429.1 - 1.4e-19 70.6 0.2 4e-16 59.3 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45429.1 - 3.5e-06 27.0 0.1 6.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KPI45429.1 - 0.02 14.9 0.2 0.033 14.2 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 KPI45430.1 - 1.4e-17 63.3 0.5 6.3e-16 57.9 0.1 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI45430.1 - 1.4e-08 34.9 0.0 1.4e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI45430.1 - 1.7e-08 34.1 0.0 9.6e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KPI45430.1 - 1.8e-07 30.6 0.3 3.2e-06 26.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KPI45430.1 - 1e-06 28.2 0.1 7.3e-05 22.2 0.0 2.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI45430.1 - 0.0032 17.5 0.3 0.2 11.7 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KPI45430.1 - 0.045 13.0 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KPI45430.1 - 0.067 12.8 6.3 0.81 9.2 0.0 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KPI45430.1 - 1.6 8.0 3.2 5.9 6.1 0.2 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPI45430.1 - 3.3 6.3 4.0 1.6 7.4 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein PH PF00169.29 KPI45431.1 - 1.8e-07 31.6 0.0 6.1e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 PH domain zf-RING_11 PF17123.5 KPI45432.1 - 3e-06 26.9 8.6 5.8e-06 26.0 8.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KPI45432.1 - 1.5e-05 25.2 5.5 2.6e-05 24.5 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI45432.1 - 9.9e-05 22.3 1.0 0.00018 21.4 1.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KPI45432.1 - 0.057 13.3 6.2 0.099 12.5 6.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI45432.1 - 0.097 12.5 8.3 0.17 11.7 8.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fibrillin_U_N PF18193.1 KPI45432.1 - 0.1 12.7 0.3 0.1 12.7 0.3 1.7 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain zf-RING_5 PF14634.6 KPI45432.1 - 0.15 12.1 5.5 0.25 11.3 5.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain N-SET PF11764.8 KPI45433.1 - 1.3e-43 149.1 0.2 1.3e-43 149.1 0.2 3.3 2 1 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 KPI45433.1 - 1.2e-21 77.9 0.1 1.2e-21 77.9 0.1 3.3 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.8 KPI45433.1 - 3.8e-13 48.9 0.1 8.1e-13 47.8 0.1 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Cpn60_TCP1 PF00118.24 KPI45434.1 - 4.9e-143 477.3 10.3 5.6e-143 477.1 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KPI45434.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat PAD_M PF08527.10 KPI45434.1 - 0.091 12.4 0.4 4.8 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain DUF5442 PF17514.2 KPI45434.1 - 0.15 12.3 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Ppx-GppA PF02541.16 KPI45435.1 - 7.7e-36 124.0 0.0 1.6e-28 99.9 0.0 2.2 2 0 0 2 2 2 2 Ppx/GppA phosphatase family F-box-like PF12937.7 KPI45436.1 - 0.084 12.8 0.6 0.28 11.1 0.3 2.1 2 0 0 2 2 2 0 F-box-like adh_short_C2 PF13561.6 KPI45437.1 - 2.6e-56 190.8 0.0 3.3e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI45437.1 - 3.3e-47 160.5 0.0 4.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI45437.1 - 1.9e-12 47.5 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KPI45437.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TIR_2 PF13676.6 KPI45437.1 - 0.0031 18.1 0.0 0.0081 16.8 0.0 1.7 2 0 0 2 2 2 1 TIR domain PALP PF00291.25 KPI45437.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 KPI45437.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain M20_dimer PF07687.14 KPI45438.1 - 1.1e-18 67.2 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KPI45438.1 - 5.2e-16 59.0 0.0 1.6e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KPI45438.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Y_phosphatase PF00102.27 KPI45439.1 - 2.8e-47 161.3 0.0 1e-20 74.3 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KPI45439.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KPI45439.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 KPI45439.1 - 0.062 13.1 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PLA2_B PF01735.18 KPI45440.1 - 1.3e-195 650.5 1.2 1.7e-195 650.2 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Polyketide_cyc2 PF10604.9 KPI45440.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport UNC-50 PF05216.13 KPI45441.1 - 4.5e-05 23.1 4.7 4.5e-05 23.1 4.7 1.8 2 0 0 2 2 2 1 UNC-50 family MARVEL PF01284.23 KPI45441.1 - 7.7e-05 22.8 14.9 0.0001 22.4 14.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4199 PF13858.6 KPI45441.1 - 0.04 14.3 10.2 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SelK_SelG PF10961.8 KPI45441.1 - 0.089 13.4 3.3 0.098 13.3 0.8 2.2 1 1 1 2 2 2 0 Selenoprotein SelK_SelG COX7a PF02238.15 KPI45441.1 - 0.54 10.7 2.4 29 5.2 0.4 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII SUR7 PF06687.12 KPI45441.1 - 0.67 9.6 15.0 0.24 11.0 0.5 2.2 1 1 0 2 2 2 0 SUR7/PalI family DUF4282 PF14110.6 KPI45441.1 - 2.1 9.1 13.2 5 7.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) DUF4328 PF14219.6 KPI45441.1 - 6.1 6.4 8.1 34 3.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) DUF3602 PF12223.8 KPI45442.1 - 4.7e-12 46.3 13.0 1.1e-10 42.0 3.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) CHCH PF06747.13 KPI45444.1 - 3.4e-05 23.8 5.3 5.3e-05 23.2 5.3 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KPI45444.1 - 0.00079 19.6 0.4 0.0012 19.0 0.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COX17 PF05051.13 KPI45444.1 - 0.092 13.1 2.0 0.17 12.3 1.6 1.6 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KPI45444.1 - 0.093 13.0 3.2 0.18 12.1 3.2 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NmrA PF05368.13 KPI45446.1 - 4.1e-21 75.6 0.0 5.5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KPI45446.1 - 2.1e-15 57.1 0.0 3.3e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KPI45446.1 - 9.4e-07 29.3 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KPI45446.1 - 0.00019 20.7 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KPI45446.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KPI45446.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI45446.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KPI45446.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KPI45446.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF2062 PF09835.9 KPI45447.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) TLD PF07534.16 KPI45449.1 - 5.9e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 KPI45449.1 - 0.0036 18.3 0.5 0.02 15.9 0.5 2.4 1 1 0 1 1 1 1 Domain of unknown function NAD_binding_10 PF13460.6 KPI45451.1 - 7.1e-15 55.4 0.4 1.5e-14 54.3 0.2 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KPI45451.1 - 2.8e-13 50.0 0.0 3.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KPI45451.1 - 2.3e-05 24.8 0.1 4.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KPI45451.1 - 9.5e-05 21.5 0.1 0.00028 20.0 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KPI45451.1 - 0.00014 22.1 0.1 0.00026 21.2 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KPI45451.1 - 0.00057 20.1 0.2 0.0018 18.6 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KPI45451.1 - 0.00073 19.1 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KPI45451.1 - 0.043 13.9 0.1 0.078 13.1 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cecropin PF00272.19 KPI45451.1 - 0.18 11.6 1.1 0.46 10.2 1.1 1.7 1 0 0 1 1 1 0 Cecropin family NIPSNAP PF07978.13 KPI45452.1 - 9.8e-15 54.6 0.0 4.5e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 NIPSNAP GMC_oxred_N PF00732.19 KPI45454.1 - 1.8e-65 221.3 0.0 2.3e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KPI45454.1 - 2.1e-28 99.6 0.0 5e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KPI45454.1 - 1e-09 38.0 2.2 0.00077 18.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KPI45454.1 - 3.7e-09 36.6 3.3 2e-08 34.2 3.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI45454.1 - 7.3e-07 28.6 0.2 1.4e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI45454.1 - 4.7e-06 26.1 0.0 0.00057 19.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI45454.1 - 1.9e-05 24.0 0.0 0.093 11.8 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI45454.1 - 1.9e-05 24.1 0.0 0.088 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI45454.1 - 3.4e-05 24.0 0.8 9.2e-05 22.6 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI45454.1 - 0.0021 18.1 0.3 0.92 9.5 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KPI45454.1 - 0.011 15.1 2.3 2.1 7.6 1.4 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KPI45454.1 - 0.018 14.3 0.3 0.033 13.4 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KPI45454.1 - 0.022 15.3 0.0 0.19 12.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI45454.1 - 0.053 12.2 0.1 0.094 11.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KPI45454.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KPI45454.1 - 0.088 13.1 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 KPI45454.1 - 0.16 10.8 0.3 0.27 10.0 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Voltage_CLC PF00654.20 KPI45456.1 - 1.8e-88 297.2 28.4 1.8e-88 297.2 28.4 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KPI45456.1 - 0.047 14.1 0.0 0.7 10.4 0.0 2.5 2 0 0 2 2 2 0 CBS domain DUF996 PF06195.13 KPI45456.1 - 1.3 9.4 8.5 10 6.4 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF996) Fungal_trans PF04082.18 KPI45457.1 - 4.4e-07 29.2 2.5 1.6e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain CS PF04969.16 KPI45458.1 - 3.2e-16 60.1 0.2 6.4e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 CS domain Na_H_Exchanger PF00999.21 KPI45459.1 - 3.8e-24 85.2 37.4 7.2e-21 74.4 25.2 2.6 3 0 0 3 3 3 2 Sodium/hydrogen exchanger family CCDC53 PF10152.9 KPI45459.1 - 1.4 9.4 3.9 20 5.6 0.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HET PF06985.11 KPI45460.1 - 2.4e-33 115.5 0.1 4.6e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KPI45460.1 - 0.016 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4871 PF16167.5 KPI45460.1 - 0.41 10.7 2.1 11 6.1 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4871) FAD_binding_4 PF01565.23 KPI45462.1 - 6.1e-23 81.1 0.0 1.5e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain VIT1 PF01988.19 KPI45462.1 - 0.2 11.5 6.5 0.027 14.3 1.5 2.1 2 0 0 2 2 2 0 VIT family AAA PF00004.29 KPI45463.1 - 4.7e-20 72.4 0.0 1.1e-18 67.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI45463.1 - 0.00056 20.3 0.4 0.0023 18.3 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 KPI45463.1 - 0.0016 18.4 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 KPI45463.1 - 0.0044 16.4 0.3 0.0078 15.6 0.3 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KPI45463.1 - 0.01 16.1 0.5 0.15 12.3 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 KPI45463.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain AAA_30 PF13604.6 KPI45463.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KPI45463.1 - 0.019 15.3 0.0 0.074 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KPI45463.1 - 0.024 15.2 0.1 0.19 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KPI45463.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF851 PF05867.11 KPI45463.1 - 0.033 13.7 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF851) Vps36_ESCRT-II PF11605.8 KPI45463.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DnaB_C PF03796.15 KPI45463.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KPI45463.1 - 0.035 13.5 0.7 0.098 12.0 0.5 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KPI45463.1 - 0.041 13.6 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KPI45463.1 - 0.044 14.0 0.4 0.34 11.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.6 KPI45463.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KPI45463.1 - 0.069 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KPI45463.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KPI45463.1 - 0.091 12.4 0.0 0.89 9.2 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.12 KPI45463.1 - 0.12 11.7 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KPI45463.1 - 0.13 11.9 0.8 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KPI45463.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region adh_short PF00106.25 KPI45464.1 - 1.1e-11 44.6 0.1 2.5e-05 23.8 0.1 2.6 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45464.1 - 4.6e-06 26.4 0.1 0.014 14.9 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45464.1 - 0.13 12.1 1.4 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 KR domain Exo_endo_phos PF03372.23 KPI45465.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2Fe-2S_thioredx PF01257.19 KPI45466.1 - 1.9e-59 199.7 0.1 2.4e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin PikAIV_N PF18605.1 KPI45466.1 - 0.12 12.0 0.8 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Taxilin PF09728.9 KPI45468.1 - 2.3e-81 273.4 60.0 2.3e-81 273.4 60.0 2.2 2 1 1 3 3 3 1 Myosin-like coiled-coil protein TMF_DNA_bd PF12329.8 KPI45468.1 - 0.02 14.8 0.8 0.02 14.8 0.8 7.0 4 2 3 7 7 7 0 TATA element modulatory factor 1 DNA binding Sec34 PF04136.15 KPI45468.1 - 1.2 9.0 32.7 1.5 8.7 5.0 4.7 2 2 2 4 4 4 0 Sec34-like family Amidohydro_1 PF01979.20 KPI45469.1 - 3.3e-24 85.8 0.1 4.4e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI45469.1 - 2.3e-10 40.5 0.1 1.8e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family GTP_EFTU PF00009.27 KPI45471.1 - 1.5e-57 194.3 0.1 3.3e-57 193.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KPI45471.1 - 1.7e-32 111.3 0.0 3.7e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KPI45471.1 - 3.2e-21 75.1 0.5 1.2e-20 73.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor G C-terminus EFG_IV PF03764.18 KPI45471.1 - 1.8e-18 66.4 0.7 3.5e-10 39.7 0.0 2.5 1 1 1 2 2 2 2 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KPI45471.1 - 3.1e-13 49.9 0.1 1e-12 48.3 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KPI45471.1 - 2.6e-07 30.5 0.2 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain adh_short PF00106.25 KPI45472.1 - 4.5e-51 173.1 0.0 5.6e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45472.1 - 8.9e-35 120.3 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45472.1 - 4e-13 49.7 0.0 5.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KPI45472.1 - 1e-10 41.5 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KPI45472.1 - 0.00049 19.6 0.1 0.0054 16.2 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KPI45472.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Hydrolase_4 PF12146.8 KPI45473.1 - 2.5e-07 30.2 0.0 5.6e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI45473.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KPI45473.1 - 0.00061 19.5 0.0 0.0041 16.7 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 KPI45473.1 - 0.044 12.6 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Perm-CXXC PF15629.6 KPI45474.1 - 0.32 11.3 2.9 0.56 10.5 2.9 1.3 1 0 0 1 1 1 0 Permuted single zf-CXXC unit ACC_central PF08326.12 KPI45475.1 - 6.5e-246 818.1 0.0 3.2e-160 534.8 0.0 2.1 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KPI45475.1 - 1.2e-175 584.9 0.0 2e-175 584.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KPI45475.1 - 3.6e-53 180.2 0.0 6.7e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KPI45475.1 - 5.1e-28 97.8 0.1 9.8e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KPI45475.1 - 8.4e-24 83.8 0.0 5.1e-21 74.8 0.0 3.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KPI45475.1 - 8.3e-16 57.6 0.1 2e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KPI45475.1 - 4.6e-05 23.0 0.0 0.00016 21.2 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KPI45475.1 - 0.00042 20.4 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 KPI45475.1 - 0.0046 17.2 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 KPI45475.1 - 0.0094 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KPI45475.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Methyltransf_25 PF13649.6 KPI45476.1 - 0.0045 17.6 0.0 0.009 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45476.1 - 0.032 15.0 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KPI45476.1 - 0.033 14.8 0.0 0.071 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 4HBT PF03061.22 KPI45477.1 - 4.1e-07 30.3 0.4 8.3e-07 29.3 0.3 1.6 2 0 0 2 2 2 1 Thioesterase superfamily BNR PF02012.20 KPI45478.1 - 0.00061 19.4 1.0 2.4 8.5 0.1 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_2 PF13088.6 KPI45478.1 - 0.0054 16.1 0.3 0.44 9.8 0.1 2.3 2 0 0 2 2 2 2 BNR repeat-like domain F5_F8_type_C PF00754.25 KPI45478.1 - 0.18 11.9 2.2 1.5 8.9 0.3 2.8 2 1 0 3 3 3 0 F5/8 type C domain Sortilin-Vps10 PF15902.5 KPI45478.1 - 0.28 10.0 1.1 3.8 6.2 0.1 2.2 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 KPI45478.1 - 2.7 8.3 0.0 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 BNR-Asp box repeat MFS_1 PF07690.16 KPI45479.1 - 4e-28 98.3 28.1 4e-28 98.3 28.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI45479.1 - 1.2e-11 44.1 5.3 1.2e-11 44.1 5.3 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter Zn_clus PF00172.18 KPI45480.1 - 0.0014 18.7 8.2 0.0026 17.9 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KPI45480.1 - 0.0083 15.0 0.2 0.016 14.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain SHR3_chaperone PF08229.11 KPI45481.1 - 9.7e-54 181.2 0.2 2.5e-51 173.3 0.2 2.0 1 1 0 1 1 1 1 ER membrane protein SH3 SARAF PF06682.12 KPI45481.1 - 0.033 13.8 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis NAD_binding_10 PF13460.6 KPI45482.1 - 2.3e-08 34.1 0.0 2e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI45482.1 - 1.4e-05 24.7 0.0 4.8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KPI45482.1 - 7.6e-05 21.8 0.0 0.00054 19.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KPI45482.1 - 0.0036 16.5 0.0 0.35 10.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KPI45482.1 - 0.015 14.4 0.0 0.64 9.1 0.0 2.8 3 0 0 3 3 3 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KPI45482.1 - 0.065 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KPI45482.1 - 0.083 12.3 0.0 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase zf-RING_2 PF13639.6 KPI45484.1 - 4.6e-09 36.5 6.9 8.5e-09 35.6 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KPI45484.1 - 1.8e-07 30.8 1.2 3.7e-07 29.8 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KPI45484.1 - 2e-06 27.6 3.3 3.4e-06 26.9 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPI45484.1 - 2.1e-06 27.5 3.9 3.8e-06 26.7 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI45484.1 - 6.1e-06 26.0 1.3 1.2e-05 25.0 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI45484.1 - 4.4e-05 23.2 5.1 8.1e-05 22.4 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KPI45484.1 - 8.1e-05 22.2 4.8 0.00017 21.1 4.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KPI45484.1 - 0.00039 20.4 4.6 0.00077 19.4 4.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KPI45484.1 - 0.062 13.5 3.7 0.15 12.3 3.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KPI45484.1 - 0.095 13.0 10.0 0.3 11.4 9.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Ebola_NP PF05505.12 KPI45484.1 - 0.17 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein RINGv PF12906.7 KPI45484.1 - 0.22 11.7 6.4 0.62 10.2 6.4 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KPI45484.1 - 0.22 11.7 5.7 1.6 9.0 5.1 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KPI45484.1 - 0.35 10.9 4.3 0.89 9.7 4.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KPI45484.1 - 0.41 10.5 5.9 6.3 6.7 0.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF588 PF04535.12 KPI45484.1 - 0.58 9.9 3.5 2.5 7.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF588) zf-RING-like PF08746.11 KPI45484.1 - 1.5 9.2 6.5 5.4 7.4 4.0 2.3 2 0 0 2 2 2 0 RING-like domain SAGA-Tad1 PF12767.7 KPI45485.1 - 5.5e-50 170.3 0.0 7.7e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TENA_THI-4 PF03070.16 KPI45487.1 - 1.6e-05 24.8 0.0 0.00037 20.4 0.0 2.6 2 1 0 2 2 2 1 TENA/THI-4/PQQC family LtrA PF06772.11 KPI45488.1 - 8.5e-24 84.4 22.9 8.5e-24 84.4 22.9 2.2 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) zf-4CXXC_R1 PF10497.9 KPI45489.1 - 3e-05 24.2 11.5 3e-05 24.2 11.5 2.4 2 0 0 2 2 2 2 Zinc-finger domain of monoamine-oxidase A repressor R1 ZZ PF00569.17 KPI45489.1 - 7.5e-05 22.5 9.8 7.5e-05 22.5 9.8 2.8 3 0 0 3 3 3 1 Zinc finger, ZZ type JmjC PF02373.22 KPI45489.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.6 KPI45489.1 - 0.08 13.4 0.4 7.7 7.0 0.0 2.7 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase FAA_hydrolase PF01557.18 KPI45490.1 - 2.2e-48 164.8 0.0 1.5e-46 158.8 0.0 2.1 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SNF2_N PF00176.23 KPI45491.1 - 8e-67 225.4 0.1 3.7e-65 219.9 0.1 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI45491.1 - 3.5e-15 56.3 0.0 8.6e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI45491.1 - 3.7e-08 33.6 0.0 1.3e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2335 PF10097.9 KPI45491.1 - 0.017 15.0 0.1 0.071 13.1 0.1 2.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) VIT PF08487.10 KPI45491.1 - 0.12 12.6 0.4 0.42 10.9 0.1 2.1 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain DZR PF12773.7 KPI45491.1 - 0.21 11.6 0.6 0.41 10.7 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 KPI45493.1 - 1.1e-59 201.9 0.0 1.4e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45493.1 - 5.9e-31 107.7 0.0 8.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KPI45493.1 - 0.0094 14.9 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain OCIA PF07051.11 KPI45493.1 - 0.15 12.1 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) Pkinase_fungal PF17667.1 KPI45493.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FAD_binding_3 PF01494.19 KPI45494.1 - 1.1e-14 54.5 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI45494.1 - 1.2e-05 25.1 0.2 0.00016 21.4 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI45494.1 - 1.5e-05 24.4 0.0 7.7e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI45494.1 - 0.00068 18.5 0.0 0.0015 17.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KPI45494.1 - 0.0019 18.4 0.1 0.0064 16.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI45494.1 - 0.0021 18.6 0.0 0.0076 16.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI45494.1 - 0.0027 17.0 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 KPI45494.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 KPI45494.1 - 0.017 14.2 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KPI45494.1 - 0.042 12.7 0.4 4.8 5.9 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 KPI45494.1 - 0.042 12.9 0.1 0.078 12.0 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KPI45494.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KPI45494.1 - 0.32 10.3 4.2 0.14 11.5 0.4 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Rif1_N PF12231.8 KPI45495.1 - 1.8e-14 53.6 0.3 2.3e-14 53.2 0.3 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Abhydrolase_3 PF07859.13 KPI45496.1 - 2.9e-16 60.0 0.0 4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KPI45496.1 - 9.4e-12 44.8 0.0 2.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KPI45496.1 - 2.1e-05 23.6 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KPI45496.1 - 2.6e-05 23.3 0.0 5.6e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KPI45496.1 - 3.9e-05 23.0 0.0 0.00021 20.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KPI45496.1 - 0.00067 19.4 0.0 0.0018 17.9 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 KPI45496.1 - 0.0017 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S15 PF02129.18 KPI45496.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KPI45496.1 - 0.0051 15.5 0.0 0.38 9.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Pam17 PF08566.10 KPI45498.1 - 4.3e-56 189.3 0.0 5.7e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Colicin_V PF02674.16 KPI45498.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Colicin V production protein AtpR PF12966.7 KPI45498.1 - 0.021 15.3 0.6 7.9 7.0 0.1 2.4 2 0 0 2 2 2 0 N-ATPase, AtpR subunit CUE PF02845.16 KPI45499.1 - 0.0053 16.4 0.2 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 CUE domain MutS_V PF00488.21 KPI45500.1 - 1.2e-71 240.7 0.1 2.4e-71 239.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPI45500.1 - 1.6e-34 119.8 0.2 3.4e-34 118.7 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KPI45500.1 - 2e-30 105.3 0.0 4.4e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KPI45500.1 - 9.2e-08 32.5 0.0 4.9e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain II DUF4911 PF16256.5 KPI45500.1 - 0.011 15.7 0.2 0.036 14.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) MutS_IV PF05190.18 KPI45500.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV DUF2654 PF10849.8 KPI45500.1 - 0.18 12.0 0.1 0.45 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) SVWC PF15430.6 KPI45501.1 - 0.0029 17.8 1.5 38 4.6 0.0 3.9 3 1 1 4 4 4 3 Single domain von Willebrand factor type C MFS_1 PF07690.16 KPI45502.1 - 1.4e-32 113.0 16.9 1.9e-32 112.6 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI45502.1 - 0.00087 18.7 1.4 0.00087 18.7 1.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KPI45502.1 - 0.0011 17.9 0.2 0.0011 17.9 0.2 1.8 2 0 0 2 2 2 1 MFS_1 like family DUF5051 PF16473.5 KPI45503.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.5 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like RNase_T PF00929.24 KPI45503.1 - 0.014 16.0 0.0 0.027 15.0 0.0 1.5 1 1 0 1 1 1 0 Exonuclease SPT6_acidic PF14632.6 KPI45503.1 - 0.14 12.7 0.8 0.32 11.6 0.8 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PHO4 PF01384.20 KPI45504.1 - 3.9e-102 341.8 17.9 4.6e-102 341.5 17.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family TMEM192 PF14802.6 KPI45505.1 - 0.053 12.6 0.8 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 TMEM192 family FixQ PF05545.11 KPI45505.1 - 0.074 13.0 1.8 0.22 11.5 0.3 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2700 PF10912.8 KPI45505.1 - 0.96 9.5 5.6 2.7 8.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2700) DUF1345 PF07077.11 KPI45505.1 - 4.8 6.9 6.4 2.3 7.9 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Vpu PF00558.19 KPI45505.1 - 6.8 6.5 7.0 1.6 8.5 1.1 2.4 2 0 0 2 2 2 0 Vpu protein AMP-binding PF00501.28 KPI45506.1 - 7.3e-91 304.9 0.0 8.8e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI45506.1 - 5.3e-12 46.5 0.3 1.3e-11 45.2 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RrnaAD PF00398.20 KPI45507.1 - 0.28 10.2 0.1 0.38 9.8 0.1 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TFIIA PF03153.13 KPI45507.1 - 6.2 6.7 8.1 7.5 6.4 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.29 KPI45510.1 - 7.6e-23 81.3 0.0 1.4e-22 80.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KPI45510.1 - 4.8e-12 46.0 0.5 8.3e-12 45.3 0.5 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KPI45510.1 - 0.16 11.5 0.1 1.3 8.6 0.1 2.1 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase G-patch_2 PF12656.7 KPI45511.1 - 9.6e-16 57.6 0.7 3.3e-15 55.9 0.7 2.0 1 0 0 1 1 1 1 G-patch domain DUF3328 PF11807.8 KPI45512.1 - 1.5e-35 123.0 0.2 1.8e-35 122.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Adeno_E3_CR2 PF02439.15 KPI45514.1 - 0.06 13.1 0.9 0.13 12.1 0.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Amnionless PF14828.6 KPI45514.1 - 0.08 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless BolA PF01722.18 KPI45515.1 - 1.6e-29 102.0 0.8 2e-29 101.7 0.8 1.1 1 0 0 1 1 1 1 BolA-like protein Glyco_transf_22 PF03901.17 KPI45516.1 - 2.6e-80 270.7 8.8 3.3e-80 270.4 8.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ECSCR PF15820.5 KPI45516.1 - 0.22 11.4 0.0 0.52 10.2 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Ribosomal_L5_C PF00673.21 KPI45517.1 - 2.4e-22 78.9 0.0 3.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KPI45517.1 - 1.9e-20 72.9 0.0 5.7e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 YL1 PF05764.13 KPI45518.1 - 4.8e-50 171.0 39.2 9.8e-50 169.9 39.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KPI45518.1 - 1.5e-10 40.6 0.1 2.7e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BTV_NS2 PF04514.12 KPI45518.1 - 4 6.2 7.1 7.3 5.3 7.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 WW PF00397.26 KPI45519.1 - 2.4e-11 43.5 0.6 2.4e-11 43.5 0.6 1.9 2 0 0 2 2 2 1 WW domain PhoD PF09423.10 KPI45519.1 - 0.002 17.2 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase DUF4585 PF15232.6 KPI45519.1 - 0.034 14.2 0.0 0.034 14.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) Methyltransf_23 PF13489.6 KPI45520.1 - 1.1e-14 54.6 0.0 1.5e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI45520.1 - 5.1e-09 36.7 0.0 3.3e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45520.1 - 1.5e-07 32.0 0.0 4.5e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI45520.1 - 7.9e-06 26.5 0.0 3.9e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45520.1 - 0.00041 20.2 0.0 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI45520.1 - 0.2 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 KPI45522.1 - 6.1e-40 137.2 52.2 9.2e-40 136.6 50.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DLH PF01738.18 KPI45523.1 - 1.8e-32 112.7 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF4299 PF14132.6 KPI45523.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) Hydrolase_4 PF12146.8 KPI45523.1 - 0.12 11.6 0.1 10 5.3 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI45523.1 - 0.16 11.6 0.1 0.46 10.1 0.1 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Y_phosphatase3 PF13350.6 KPI45524.1 - 4.3e-44 151.2 0.0 6.5e-44 150.6 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KPI45524.1 - 1.5e-08 34.4 0.0 3.9e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KPI45524.1 - 0.00084 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KPI45524.1 - 0.013 15.3 0.0 0.071 12.9 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KPI45524.1 - 0.022 13.7 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3883 PF13020.6 KPI45525.1 - 0.0016 18.4 0.0 0.0069 16.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 KPI45525.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PK_C PF02887.16 KPI45525.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Iso_dh PF00180.20 KPI45526.1 - 2e-96 323.2 0.0 2.5e-95 319.6 0.0 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cutinase PF01083.22 KPI45527.1 - 2.4e-51 174.2 0.1 2.8e-51 174.0 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPI45527.1 - 0.00017 21.2 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 KPI45527.1 - 0.012 15.1 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KPI45527.1 - 0.045 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KPI45527.1 - 0.099 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KPI45527.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Response_reg PF00072.24 KPI45528.1 - 6e-22 77.9 0.3 1.3e-14 54.3 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 KPI45528.1 - 2.9e-19 69.6 0.0 6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KPI45528.1 - 5.5e-06 26.3 2.4 5.8e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KPI45528.1 - 7.5e-05 23.0 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 GAF domain PAS_9 PF13426.7 KPI45528.1 - 0.0059 16.8 0.0 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KPI45528.1 - 0.006 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KPI45528.1 - 0.012 15.8 0.0 0.19 12.0 0.0 2.9 3 0 0 3 3 3 0 PAS fold DUF3123 PF11321.8 KPI45528.1 - 7 7.4 7.8 9.5 6.9 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Eisosome1 PF12757.7 KPI45529.1 - 5.3e-39 133.3 13.8 5.3e-39 133.3 13.8 5.0 4 1 1 5 5 5 1 Eisosome protein 1 MutS_V PF00488.21 KPI45530.1 - 1.3e-54 185.1 0.4 1.4e-53 181.7 0.4 2.4 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPI45530.1 - 1.1e-40 140.0 0.0 2.1e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KPI45530.1 - 6e-32 110.2 0.1 1.3e-31 109.1 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KPI45530.1 - 1.2e-14 54.4 0.5 3.9e-14 52.8 0.5 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KPI45530.1 - 6.2e-10 39.5 0.0 1.5e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 KPI45530.1 - 0.0083 16.7 1.8 0.037 14.5 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KPI45530.1 - 0.05 13.3 0.2 0.05 13.3 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KPI45530.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KPI45530.1 - 0.48 10.8 1.8 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Axin_b-cat_bind PF08833.10 KPI45531.1 - 0.067 13.3 0.1 2.1 8.5 0.0 2.3 1 1 1 2 2 2 0 Axin beta-catenin binding domain DUF3533 PF12051.8 KPI45532.1 - 3.1e-113 378.5 16.5 3.6e-113 378.3 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) MgtE PF01769.16 KPI45533.1 - 0.0014 19.0 1.8 0.0018 18.7 1.8 1.3 1 0 0 1 1 1 1 Divalent cation transporter DUF2207 PF09972.9 KPI45533.1 - 0.9 8.2 4.0 2 7.1 4.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5336 PF17270.2 KPI45533.1 - 2.3 7.8 7.0 5.6 6.6 6.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5336) Herpes_gE PF02480.16 KPI45535.1 - 0.058 12.1 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LapA_dom PF06305.11 KPI45535.1 - 0.24 11.2 1.4 0.38 10.6 1.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Glyco_transf_20 PF00982.21 KPI45536.1 - 2.5e-143 478.2 0.0 1.4e-141 472.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KPI45536.1 - 0.0058 16.2 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 DUF4440 PF14534.6 KPI45537.1 - 0.0053 17.1 0.0 0.0075 16.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KPI45537.1 - 0.12 13.1 0.0 0.17 12.5 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain p450 PF00067.22 KPI45539.1 - 1.8e-52 178.6 0.0 2.8e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KPI45540.1 - 2.8e-29 102.2 17.3 2.8e-29 102.2 17.3 2.7 3 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI45540.1 - 1.6e-09 36.8 11.8 5.1e-09 35.1 11.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PsbN PF02468.15 KPI45540.1 - 0.19 11.6 1.1 0.75 9.7 1.1 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) PfkB PF00294.24 KPI45541.1 - 1.4e-10 41.0 0.0 3.8e-06 26.4 0.0 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Red1 PF07964.11 KPI45541.1 - 0.23 9.7 0.1 0.31 9.2 0.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Ribosomal_L36e PF01158.18 KPI45542.1 - 1.3e-41 140.7 5.7 1.5e-41 140.6 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 KPI45542.1 - 0.038 14.0 0.2 0.049 13.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Bac_rhodopsin PF01036.18 KPI45543.1 - 4.2e-46 157.3 16.4 5.1e-46 157.0 16.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.14 KPI45543.1 - 0.043 14.3 8.6 0.19 12.2 4.3 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4131 PF13567.6 KPI45543.1 - 2.2 7.9 4.9 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) tRNA-synt_1g PF09334.11 KPI45544.1 - 1e-60 205.6 0.7 1.9e-59 201.4 0.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KPI45544.1 - 1.1e-11 43.7 0.6 6.5e-08 31.3 0.3 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KPI45544.1 - 7.1e-05 22.3 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ish1 PF10281.9 KPI45544.1 - 0.098 13.0 0.7 0.38 11.1 0.1 2.3 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein MOSC PF03473.17 KPI45545.1 - 2.2e-31 108.6 0.0 4.2e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KPI45545.1 - 3.7e-23 82.1 0.0 5.3e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KPI45545.1 - 5.2e-19 68.3 0.0 2.6e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Fungal_trans PF04082.18 KPI45546.1 - 7.3e-18 64.5 1.9 2.4e-17 62.9 1.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CHCH PF06747.13 KPI45546.1 - 0.0017 18.4 0.3 0.0056 16.8 0.3 1.9 1 0 0 1 1 1 1 CHCH domain Luciferase_N PF05295.11 KPI45546.1 - 0.0088 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Luciferase/LBP N-terminal domain Myf5 PF12232.8 KPI45546.1 - 0.032 15.0 0.4 0.17 12.7 0.4 2.3 1 0 0 1 1 1 0 Myogenic determination factor 5 DUF1640 PF07798.11 KPI45547.1 - 0.22 11.6 7.8 0.54 10.3 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) NatB_MDM20 PF09797.9 KPI45548.1 - 1.9e-37 129.1 0.0 4.8e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Not1 PF04054.15 KPI45548.1 - 0.0052 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 TPR_16 PF13432.6 KPI45548.1 - 0.0065 17.1 3.7 1.5 9.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat CENP-O PF09496.10 KPI45548.1 - 0.22 11.5 3.0 6.4 6.7 0.3 2.4 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component DUF1593 PF07632.11 KPI45549.1 - 6.4e-66 222.4 0.1 9e-66 221.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KPI45549.1 - 0.0066 15.3 0.0 0.0095 14.8 0.0 1.1 1 0 0 1 1 1 1 REJ domain Ecm29 PF13001.7 KPI45550.1 - 8.6e-103 344.7 10.2 1.4e-54 185.6 1.6 3.6 3 1 1 4 4 4 2 Proteasome stabiliser Fungal_trans_2 PF11951.8 KPI45550.1 - 5.4e-12 45.2 5.2 1.7e-11 43.6 3.5 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain HEAT PF02985.22 KPI45550.1 - 0.00023 21.2 12.8 27 5.4 0.1 9.0 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 KPI45550.1 - 0.0034 17.7 18.6 0.0095 16.3 0.1 8.5 8 2 1 9 9 9 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KPI45550.1 - 0.0066 17.0 0.2 9.7 6.9 0.1 4.6 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KPI45550.1 - 0.15 11.8 4.1 0.29 10.9 0.0 3.6 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis SIR2 PF02146.17 KPI45552.1 - 4.7e-38 130.9 0.0 9.2e-37 126.7 0.0 2.1 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KPI45552.1 - 0.058 13.1 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DAHP_synth_2 PF01474.16 KPI45553.1 - 1e-192 640.5 0.0 1.2e-192 640.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MFS_1 PF07690.16 KPI45554.1 - 3.5e-07 29.5 32.6 1.5e-06 27.4 30.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KPI45554.1 - 0.00016 21.4 6.6 0.0048 16.6 4.6 3.1 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 M16C_assoc PF08367.11 KPI45555.1 - 9.7e-66 221.4 0.1 1.8e-65 220.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KPI45555.1 - 7.3e-24 84.8 0.0 2.6e-17 63.4 0.0 4.0 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPI45555.1 - 1.1e-05 25.5 0.0 5.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tyrosinase PF00264.20 KPI45556.1 - 2.5e-49 168.6 0.1 4e-49 167.9 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Hexokinase_2 PF03727.16 KPI45556.1 - 0.22 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Hexokinase COesterase PF00135.28 KPI45557.1 - 8.3e-87 292.2 0.0 1.1e-86 291.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KPI45557.1 - 1.1e-06 28.7 0.0 4.6e-05 23.4 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold 4HBT PF03061.22 KPI45557.1 - 0.023 15.0 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Peptidase_S9 PF00326.21 KPI45557.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ANAPC2 PF08672.11 KPI45558.1 - 3.5e-22 78.7 0.1 2.2e-21 76.1 0.1 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 KPI45558.1 - 7.6e-22 77.7 0.1 1.6e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Cullin family Ribosomal_60s PF00428.19 KPI45558.1 - 0.015 15.8 5.7 0.015 15.8 5.7 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein PapA_C PF16911.5 KPI45558.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Bcl-2_3 PF15286.6 KPI45558.1 - 0.17 12.6 0.8 2.3 8.9 0.0 2.7 2 1 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like VTC PF09359.10 KPI45560.1 - 7.4e-98 327.3 0.1 1.3e-97 326.5 0.1 1.4 1 0 0 1 1 1 1 VTC domain Fungal_trans PF04082.18 KPI45560.1 - 2.7e-13 49.6 0.0 5.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF202 PF02656.15 KPI45560.1 - 3e-11 43.6 5.4 5.7e-11 42.7 5.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KPI45560.1 - 2.6e-06 27.6 0.2 2.6e-06 27.6 0.2 4.6 4 1 1 5 5 5 2 SPX domain Zn_clus PF00172.18 KPI45560.1 - 0.012 15.7 1.2 0.023 14.8 1.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_3 PF13727.6 KPI45560.1 - 0.1 12.6 0.5 0.21 11.6 0.5 1.4 1 0 0 1 1 1 0 CoA-binding domain Evr1_Alr PF04777.13 KPI45561.1 - 4.6e-25 88.0 0.8 7.3e-25 87.4 0.5 1.5 1 1 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KPI45561.1 - 0.092 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 APOBEC1 Methyltransf_11 PF08241.12 KPI45563.1 - 3.3e-15 56.5 0.0 5.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 KPI45563.1 - 4.4e-15 56.2 2.7 7.8e-15 55.4 2.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 KPI45563.1 - 6.8e-14 52.3 0.0 1.6e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45563.1 - 4e-08 33.9 0.0 9.5e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45563.1 - 1.2e-06 28.4 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI45563.1 - 4.1e-06 26.7 0.0 7.4e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KPI45563.1 - 0.0015 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KPI45563.1 - 0.0029 16.9 0.0 0.0088 15.4 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KPI45563.1 - 0.0052 16.1 0.1 0.017 14.5 0.0 1.9 3 1 0 3 3 3 1 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 KPI45563.1 - 0.007 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.18 KPI45563.1 - 0.017 14.9 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 DNA methylase TPMT PF05724.11 KPI45563.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KPI45563.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MRP-L46 PF11788.8 KPI45564.1 - 9e-28 97.4 0.0 1.7e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KPI45564.1 - 0.012 15.7 0.1 0.033 14.2 0.1 1.9 1 1 0 1 1 1 0 NUDIX domain Thioredoxin_7 PF13899.6 KPI45565.1 - 1.2e-18 67.1 0.0 2.4e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KPI45565.1 - 1.8e-08 34.5 0.0 7.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 KPI45565.1 - 6e-08 32.4 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.15 KPI45565.1 - 0.0034 17.4 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KPI45565.1 - 0.012 16.0 0.4 0.024 15.1 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain DUF3176 PF11374.8 KPI45566.1 - 2.1e-29 101.9 1.3 2.1e-29 101.9 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) COX2_TM PF02790.15 KPI45566.1 - 0.096 12.8 0.1 0.3 11.3 0.1 1.9 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Peptidase_S10 PF00450.22 KPI45567.1 - 2.5e-53 182.0 1.0 4.5e-47 161.4 0.1 3.0 2 1 0 2 2 2 2 Serine carboxypeptidase Fungal_trans PF04082.18 KPI45568.1 - 1.7e-06 27.3 0.2 2.4e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_II_C_S1 PF18614.1 KPI45568.1 - 0.063 13.2 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain RecO_C PF02565.15 KPI45568.1 - 0.094 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Recombination protein O C terminal BATS PF06968.13 KPI45569.1 - 2e-23 82.3 0.1 6.3e-23 80.7 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KPI45569.1 - 1.9e-14 54.4 0.1 3.8e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DIOX_N PF14226.6 KPI45570.1 - 4.4e-26 92.0 0.3 8.1e-26 91.1 0.3 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KPI45570.1 - 6.2e-23 81.2 0.0 1.8e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KPI45570.1 - 9.8e-20 70.7 0.1 1.7e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAP3 PF10236.9 KPI45571.1 - 6.4e-72 242.4 0.0 7.7e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KPI45571.1 - 0.0034 17.8 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KPI45571.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KPI45571.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KPI45571.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cupin_2 PF07883.11 KPI45572.1 - 7.1e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KPI45572.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1857 PF08982.11 KPI45573.1 - 3.4e-43 147.0 0.0 3.8e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) GARS_C PF02843.16 KPI45573.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain DASH_Dad4 PF08650.10 KPI45574.1 - 0.056 13.4 0.0 5.4 7.1 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 NIPSNAP PF07978.13 KPI45575.1 - 2.2e-26 92.0 0.5 1.1e-23 83.4 0.1 2.0 2 0 0 2 2 2 2 NIPSNAP HhH-GPD PF00730.25 KPI45576.1 - 1.8e-06 28.3 0.0 3.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AA_permease_2 PF13520.6 KPI45577.1 - 2.4e-59 201.3 53.5 3e-59 201.0 53.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KPI45577.1 - 2.9e-21 75.6 42.1 3.9e-21 75.2 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease Oxysterol_BP PF01237.18 KPI45578.1 - 1.4e-60 205.1 5.4 4e-58 197.1 5.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DnaT PF17948.1 KPI45578.1 - 0.029 14.1 0.2 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 DnaT DNA-binding domain Peptidase_M24 PF00557.24 KPI45579.1 - 1.7e-51 174.9 0.1 2.1e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KPI45579.1 - 2.9e-18 65.9 9.0 6.6e-18 64.7 9.0 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KPI45579.1 - 0.00041 20.4 6.4 0.00093 19.2 6.4 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KPI45579.1 - 0.14 12.1 5.0 0.26 11.2 5.0 1.5 1 0 0 1 1 1 0 HIT zinc finger ATP-cone PF03477.16 KPI45579.1 - 0.14 12.7 0.0 11 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain Fungal_trans_2 PF11951.8 KPI45581.1 - 7.1e-09 35.0 0.6 1.7e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Tim17 PF02466.19 KPI45582.1 - 6.9e-27 94.0 6.1 1.1e-26 93.4 6.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DEC-1_N PF04625.13 KPI45582.1 - 0.35 9.8 4.8 0.45 9.5 4.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-RING_11 PF17123.5 KPI45583.1 - 2.5e-09 36.7 3.0 7.3e-06 25.6 1.5 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_2 PF13639.6 KPI45583.1 - 5.6e-08 33.0 11.3 2.1e-05 24.8 7.3 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KPI45583.1 - 8.4e-05 22.3 7.7 0.0069 16.2 5.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI45583.1 - 0.0017 18.3 7.6 0.006 16.5 5.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KPI45583.1 - 0.012 15.5 7.5 0.034 14.0 4.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI45583.1 - 0.13 12.2 6.1 0.85 9.5 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI45583.1 - 1.2 9.2 6.5 41 4.3 4.7 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KPI45583.1 - 1.2 8.8 6.8 2.4 7.9 6.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KPI45583.1 - 5.4 7.3 11.2 17 5.7 6.0 2.8 3 0 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KPI45583.1 - 9 6.6 8.1 20 5.4 3.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING SWIB PF02201.18 KPI45585.1 - 2.4e-28 97.8 0.0 5.6e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KPI45585.1 - 9.6e-11 41.4 0.1 2.3e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain XRCC4 PF06632.12 KPI45585.1 - 0.0035 16.3 9.5 0.0048 15.8 9.5 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 POX PF07526.11 KPI45585.1 - 0.043 14.4 0.8 0.14 12.7 0.8 2.0 1 1 0 1 1 1 0 Associated with HOX Herpes_DNAp_acc PF04929.12 KPI45585.1 - 0.34 9.8 10.0 0.5 9.3 10.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor tRNA-synt_2 PF00152.20 KPI45588.1 - 1e-74 251.5 0.0 8.6e-74 248.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KPI45588.1 - 0.015 14.7 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KPI45588.1 - 0.027 14.5 0.0 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) LUC7 PF03194.15 KPI45589.1 - 1.3e-57 195.3 0.3 3.4e-31 108.8 0.0 2.0 1 1 1 2 2 2 2 LUC7 N_terminus Tom37 PF10568.9 KPI45590.1 - 2.8e-37 127.8 1.5 5e-37 127.0 0.1 2.0 2 1 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KPI45590.1 - 2.8e-08 34.4 0.0 5.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KPI45590.1 - 4.5e-07 29.6 0.0 1.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KPI45590.1 - 0.073 13.3 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KPI45590.1 - 0.16 12.0 0.7 0.73 9.9 0.2 2.4 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_16 PF00722.21 KPI45591.1 - 8.8e-43 145.8 3.4 1.5e-42 145.1 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CD34_antigen PF06365.12 KPI45591.1 - 0.049 13.2 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family MSA_2 PF00985.17 KPI45592.1 - 0.022 15.1 1.0 0.022 15.1 1.0 5.6 4 2 1 6 6 6 0 Merozoite Surface Antigen 2 (MSA-2) family Pkinase_fungal PF17667.1 KPI45592.1 - 6.7 5.4 9.0 5.6 5.6 5.3 2.4 1 1 1 2 2 2 0 Fungal protein kinase Ecl1 PF12855.7 KPI45593.1 - 4.3e-38 132.2 6.3 9.5e-38 131.1 6.3 1.5 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KPI45593.1 - 0.0025 17.9 2.3 0.0046 17.0 2.3 1.4 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 KPI45593.1 - 0.17 11.4 4.1 0.63 9.6 4.1 1.9 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 KPI45593.1 - 0.82 9.8 5.1 8.3 6.6 5.1 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Peptidase_M24 PF00557.24 KPI45594.1 - 5e-07 29.6 0.1 2.9e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans_2 PF11951.8 KPI45595.1 - 2.5e-61 207.6 0.0 3.8e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI45595.1 - 4.4e-09 36.3 8.6 7.3e-09 35.6 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD-helicase PF00580.21 KPI45596.1 - 7.3e-61 206.4 0.3 7.3e-61 206.4 0.3 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KPI45596.1 - 3.2e-56 191.2 0.0 2.3e-55 188.4 0.0 2.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KPI45596.1 - 5.4e-32 111.1 0.0 1.2e-31 110.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KPI45596.1 - 2.3e-13 49.8 0.0 5.2e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KPI45596.1 - 8e-06 25.7 0.2 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KPI45596.1 - 8.9e-06 25.6 0.9 0.015 15.0 0.0 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KPI45596.1 - 1.7e-05 24.6 0.0 0.0028 17.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KPI45596.1 - 5.5e-05 23.5 0.7 0.1 12.9 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KPI45596.1 - 0.0034 17.2 0.4 0.0095 15.8 0.4 1.8 1 1 0 1 1 1 1 AAA domain ZZ PF00569.17 KPI45597.1 - 3.8e-12 45.8 9.5 6.3e-12 45.1 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 KPI45597.1 - 7.5e-10 39.1 6.3 6.9e-07 29.6 2.7 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KPI45597.1 - 9e-10 37.4 3.9 0.00015 21.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KPI45597.1 - 9.8e-10 37.6 4.5 7.8e-05 22.3 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KPI45597.1 - 4.9e-05 23.1 1.7 0.00018 21.3 0.5 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KPI45597.1 - 0.09 12.3 1.9 0.39 10.3 0.1 2.7 2 0 0 2 2 2 0 EF hand C1_2 PF03107.16 KPI45597.1 - 0.31 11.4 10.5 0.052 13.9 6.7 1.7 2 0 0 2 2 2 0 C1 domain zf-B_box PF00643.24 KPI45597.1 - 2.6 8.3 9.5 4.6 7.5 9.5 1.4 1 0 0 1 1 1 0 B-box zinc finger Cyclase PF04199.13 KPI45598.1 - 2.5e-14 53.7 0.0 3.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase HATPase_c_3 PF13589.6 KPI45600.1 - 7.7e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KPI45600.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HET PF06985.11 KPI45601.1 - 1.6e-12 48.0 6.0 3.3e-10 40.5 1.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 KPI45602.1 - 7e-82 275.5 0.0 1.7e-81 274.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KPI45602.1 - 1.8e-41 142.0 0.0 3.6e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KPI45602.1 - 7.2e-06 25.0 0.1 1.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KPI45602.1 - 3.5e-05 23.2 0.1 0.0014 17.9 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KPI45602.1 - 8.9e-05 21.7 0.2 0.00013 21.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KPI45602.1 - 0.00013 21.3 0.1 0.00032 20.0 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KPI45602.1 - 0.00042 19.8 0.1 0.00065 19.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI45602.1 - 0.003 16.8 0.2 0.0045 16.3 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI45602.1 - 0.0096 15.5 0.0 0.027 14.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KPI45602.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KPI45602.1 - 0.023 14.9 0.1 0.063 13.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KPI45602.1 - 0.033 13.3 0.2 0.053 12.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KPI45602.1 - 0.05 12.7 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Sugar_tr PF00083.24 KPI45603.1 - 5.8e-75 252.9 22.2 6.7e-75 252.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45603.1 - 2.2e-20 72.9 37.2 9.4e-13 47.8 28.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KPI45603.1 - 0.092 13.3 1.7 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DHHA2 PF02833.14 KPI45604.1 - 2.3e-19 70.0 0.9 3.7e-19 69.3 0.9 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KPI45604.1 - 1.2e-07 31.9 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 DHH family Bap31_Bap29_C PF18035.1 KPI45604.1 - 0.0098 15.9 1.7 0.041 13.9 1.7 2.1 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Orn_Arg_deC_N PF02784.16 KPI45605.1 - 1.6e-79 266.8 0.0 2.2e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KPI45605.1 - 3.1e-20 72.2 0.0 4.2e-20 71.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KPI45605.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ATP-grasp_6 PF18419.1 KPI45605.1 - 0.13 11.9 0.0 18 5.0 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp-like domain GGDEF_2 PF17853.1 KPI45605.1 - 0.16 12.2 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain MFS_1 PF07690.16 KPI45606.1 - 5.1e-51 173.6 33.4 5.1e-51 173.6 33.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI45606.1 - 1.5e-12 47.2 4.7 1.5e-12 47.2 4.7 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KPI45606.1 - 8e-07 28.7 6.2 8e-07 28.7 6.2 2.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB SMN PF06003.12 KPI45606.1 - 0.00072 18.9 0.3 0.0011 18.3 0.3 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Pam17 PF08566.10 KPI45606.1 - 0.12 12.2 2.9 1.3 8.8 0.1 3.3 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 RNB PF00773.19 KPI45607.1 - 3.8e-96 322.3 0.0 5.4e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KPI45607.1 - 3.3e-30 104.7 0.0 7.4e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KPI45607.1 - 1e-24 86.3 2.0 2.1e-24 85.3 2.0 1.5 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KPI45607.1 - 4.8e-22 77.8 0.0 1.1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KPI45607.1 - 7.1e-14 52.2 0.1 2e-13 50.7 0.1 1.8 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KPI45607.1 - 7.2e-06 26.1 0.0 0.0025 18.0 0.0 3.1 3 0 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 KPI45607.1 - 0.023 15.0 0.2 0.066 13.5 0.2 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal PIN_9 PF18477.1 KPI45607.1 - 0.043 14.1 3.5 7.4 6.9 0.1 3.3 3 0 0 3 3 3 0 PIN like domain NYN_YacP PF05991.11 KPI45607.1 - 3.1 7.7 5.6 0.6 10.0 0.0 2.5 3 0 0 3 3 3 0 YacP-like NYN domain CR6_interact PF10147.9 KPI45609.1 - 0.0013 18.5 3.8 0.002 17.9 3.8 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RRM_1 PF00076.22 KPI45610.1 - 8.1e-18 64.0 0.1 1.4e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KPI45610.1 - 0.13 12.0 1.0 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease B OB domain DSBA PF01323.20 KPI45611.1 - 4.7e-15 55.9 0.0 1.4e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Pescadillo_N PF06732.11 KPI45612.1 - 2.2e-120 401.3 0.3 2.2e-120 401.3 0.3 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KPI45612.1 - 0.001 19.5 0.0 0.0062 16.9 0.0 2.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KPI45612.1 - 0.0016 18.8 0.0 0.0069 16.7 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KPI45612.1 - 0.16 12.3 0.1 0.75 10.1 0.1 2.3 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain PEX11 PF05648.14 KPI45612.1 - 4.5 6.7 5.8 28 4.1 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Astro_capsid_p PF12226.8 KPI45612.1 - 7.8 5.5 25.7 0.043 13.0 12.9 2.6 2 1 0 2 2 2 0 Turkey astrovirus capsid protein Cep57_MT_bd PF06657.13 KPI45613.1 - 0.0031 17.9 0.4 0.0031 17.9 0.4 3.2 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 LMBR1 PF04791.16 KPI45613.1 - 1.2 8.0 10.4 1.7 7.5 10.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CH PF00307.31 KPI45614.1 - 3.6e-75 249.2 0.0 7.8e-21 74.3 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KPI45614.1 - 8.5e-06 26.1 2.1 1.9e-05 25.0 0.8 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KPI45614.1 - 0.00099 18.5 0.4 0.81 9.4 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KPI45614.1 - 0.0012 18.6 0.3 0.025 14.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain CAMSAP_CH PF11971.8 KPI45614.1 - 0.011 15.5 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 CAMSAP CH domain OmpA_like PF16961.5 KPI45615.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family Abhydrolase_3 PF07859.13 KPI45616.1 - 1e-40 139.8 0.0 1.4e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPI45616.1 - 4.1e-07 29.2 0.0 5.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KPI45616.1 - 0.0021 17.0 0.2 0.024 13.5 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KPI45616.1 - 0.0074 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KPI45616.1 - 0.029 13.8 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0175 PF03683.13 KPI45616.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Sec10 PF07393.11 KPI45617.1 - 9.6e-131 437.5 0.0 3.4e-130 435.7 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec10 F-box PF00646.33 KPI45617.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KPI45617.1 - 0.00038 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF2097 PF09870.9 KPI45617.1 - 0.031 14.5 1.5 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2097) TSNAXIP1_N PF15739.5 KPI45617.1 - 5.5 7.4 7.9 1.9 8.9 3.7 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus TUG-UBL1 PF11470.8 KPI45618.1 - 8.8e-25 86.7 0.0 2e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain DUF1499 PF07386.11 KPI45618.1 - 0.021 15.4 0.5 0.066 13.8 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) CorA PF01544.18 KPI45620.1 - 7.2e-15 55.1 0.2 1.1e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_trans_2 PF11951.8 KPI45621.1 - 3.5e-15 55.7 3.8 3.3e-13 49.2 3.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KPI45622.1 - 2.4e-25 88.5 0.7 4.8e-25 87.6 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI45622.1 - 1.2e-20 73.9 1.5 1.8e-20 73.2 1.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI45622.1 - 1.8e-05 25.8 0.3 3.4e-05 24.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KPI45622.1 - 0.001 18.9 0.1 0.0083 16.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Abhydrolase_4 PF08386.10 KPI45623.1 - 3.7e-17 62.3 0.0 7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KPI45623.1 - 2.2e-10 40.6 0.0 5.6e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.20 KPI45624.1 - 5.1e-53 179.3 1.3 5.1e-53 179.3 1.3 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KPI45624.1 - 4.9e-46 156.7 4.1 4.9e-46 156.7 4.1 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KPI45624.1 - 5.1e-24 85.7 2.7 9.8e-23 81.5 2.7 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KPI45624.1 - 1.8e-18 66.0 0.0 5.7e-18 64.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KPI45624.1 - 1.6e-17 63.4 0.0 3.4e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KPI45624.1 - 8.4e-10 38.8 1.9 1e-06 28.7 1.2 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KPI45624.1 - 1.2e-07 32.3 0.0 1e-06 29.3 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KPI45624.1 - 0.1 12.8 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.22 KPI45625.1 - 1.1e-22 80.7 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TPR_12 PF13424.6 KPI45625.1 - 7e-06 26.2 1.0 0.049 13.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KPI45625.1 - 0.0019 18.7 0.1 0.017 15.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ACTL7A_N PF16840.5 KPI45626.1 - 0.44 10.7 0.1 0.44 10.7 0.1 2.7 3 1 1 4 4 4 0 Actin-like protein 7A N-terminus Iso_dh PF00180.20 KPI45627.1 - 1.1e-83 281.3 0.0 1.3e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.22 KPI45628.1 - 1.9e-52 178.6 0.0 2.9e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 KPI45629.1 - 1.9e-23 83.3 0.0 4.2e-23 82.2 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KPI45629.1 - 0.019 15.0 1.1 4.8 7.4 0.0 3.5 3 0 0 3 3 3 0 NHL repeat Arylesterase PF01731.20 KPI45629.1 - 0.093 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Arylesterase PQQ_3 PF13570.6 KPI45629.1 - 1.8 9.2 4.5 11 6.7 0.2 3.7 5 0 0 5 5 5 0 PQQ-like domain TraG-D_C PF12696.7 KPI45630.1 - 0.22 11.5 3.4 0.4 10.7 3.4 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF1180 PF06679.12 KPI45630.1 - 1.1 9.7 6.8 0.54 10.6 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) tRNA-synt_1g PF09334.11 KPI45631.1 - 1e-08 34.4 0.0 1.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KPI45631.1 - 2.9e-05 22.5 0.1 9.1e-05 20.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KPI45631.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Filament PF00038.21 KPI45632.1 - 0.00064 19.4 3.2 0.0015 18.2 3.2 1.6 1 0 0 1 1 1 1 Intermediate filament protein Lzipper-MIP1 PF14389.6 KPI45632.1 - 0.011 16.0 2.3 0.093 13.0 0.6 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 EMP24_GP25L PF01105.24 KPI45632.1 - 0.075 13.0 1.1 0.19 11.7 0.9 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD BBP1_C PF15272.6 KPI45632.1 - 0.4 10.5 1.9 0.73 9.6 1.9 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TACC_C PF05010.14 KPI45632.1 - 0.96 9.2 6.7 0.19 11.5 0.3 2.6 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 KPI45632.1 - 1.8 7.3 12.8 0.4 9.5 3.7 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Aa_trans PF01490.18 KPI45633.1 - 3.6e-27 95.1 24.3 5.3e-27 94.6 24.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C69 PF03577.15 KPI45635.1 - 1.4e-25 90.1 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KPI45635.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Sugar_tr PF00083.24 KPI45636.1 - 6.8e-73 246.1 18.5 8.3e-73 245.8 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45636.1 - 8.7e-18 64.4 27.5 5.9e-17 61.6 23.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3042 PF11240.8 KPI45636.1 - 0.22 11.6 1.5 0.94 9.5 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Mito_carr PF00153.27 KPI45637.1 - 3.9e-39 132.5 2.4 1.3e-15 57.1 0.2 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.21 KPI45639.1 - 1.1e-98 331.2 0.0 1.6e-98 330.6 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF5628 PF18621.1 KPI45639.1 - 0.16 12.4 0.0 23 5.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5628) RQC PF09382.10 KPI45641.1 - 4.2e-24 84.5 0.2 1.2e-23 83.0 0.2 1.9 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 KPI45641.1 - 5.5e-22 78.4 0.6 1.2e-21 77.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI45641.1 - 4.9e-20 71.9 0.0 7.8e-18 64.8 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KPI45641.1 - 8.3e-16 58.5 6.5 3.4e-15 56.5 6.5 2.2 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KPI45641.1 - 2.2e-06 27.8 0.2 2.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BRF1 PF07741.13 KPI45641.1 - 0.0057 17.0 1.9 0.0057 17.0 1.9 3.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain HTH_9 PF08221.11 KPI45641.1 - 0.19 11.9 0.3 2.3 8.4 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ADH_N PF08240.12 KPI45643.1 - 1.4e-28 99.0 0.7 2.2e-28 98.3 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KPI45643.1 - 2.8e-10 40.3 0.0 0.00013 21.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KPI45643.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Amidohydro_1 PF01979.20 KPI45645.1 - 1.4e-57 195.6 0.0 1.7e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KPI45645.1 - 2.8e-09 37.0 0.7 3.1e-06 26.9 0.0 2.8 2 1 1 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 KPI45645.1 - 0.041 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase TauD PF02668.16 KPI45647.1 - 6e-25 88.5 0.0 9e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_114 PF03537.13 KPI45648.1 - 1.3e-80 270.1 0.7 1.5e-80 269.8 0.7 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Tir_receptor_C PF07489.11 KPI45648.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Sec34 PF04136.15 KPI45649.1 - 0.038 13.9 3.3 0.073 13.0 3.3 1.4 1 0 0 1 1 1 0 Sec34-like family Phage_fiber_2 PF03406.13 KPI45649.1 - 0.071 12.7 0.1 0.24 11.0 0.1 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat KLRAQ PF10205.9 KPI45649.1 - 0.34 11.2 3.4 1.4 9.2 1.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.10 KPI45649.1 - 2.9 8.1 5.0 0.5 10.5 0.9 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA PF00004.29 KPI45650.1 - 2.4e-55 186.5 0.0 3.4e-43 147.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KPI45650.1 - 7.4e-28 96.8 0.6 1.5e-27 95.8 0.6 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KPI45650.1 - 6.5e-16 57.9 0.1 6.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KPI45650.1 - 5.5e-10 39.9 3.9 0.0008 19.8 0.1 4.3 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KPI45650.1 - 2e-07 31.1 0.3 0.00013 21.9 0.1 3.1 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 KPI45650.1 - 1.2e-06 28.7 0.0 0.064 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KPI45650.1 - 1.1e-05 25.5 0.0 0.07 13.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KPI45650.1 - 1.8e-05 24.7 0.0 0.17 11.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KPI45650.1 - 4e-05 23.9 0.7 0.98 9.7 0.1 3.8 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KPI45650.1 - 5.8e-05 22.9 0.0 0.015 15.1 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KPI45650.1 - 6.5e-05 23.5 0.0 0.1 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KPI45650.1 - 0.00012 21.6 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 KPI45650.1 - 0.00014 21.2 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain TsaE PF02367.17 KPI45650.1 - 0.00014 21.9 0.1 0.23 11.4 0.0 2.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KPI45650.1 - 0.00023 21.3 0.0 0.64 10.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KPI45650.1 - 0.00051 19.8 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KPI45650.1 - 0.00079 19.8 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 KPI45650.1 - 0.0012 18.4 2.0 1.3 8.6 0.1 3.8 2 2 1 4 4 4 1 AAA domain Zeta_toxin PF06414.12 KPI45650.1 - 0.013 14.8 0.0 6 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KPI45650.1 - 0.013 14.9 0.0 0.78 9.1 0.1 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KPI45650.1 - 0.016 15.6 0.0 3.4 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KPI45650.1 - 0.02 14.9 0.1 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 KPI45650.1 - 0.03 14.5 0.0 6.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KPI45650.1 - 0.068 13.1 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KPI45650.1 - 0.097 12.6 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 KPI45650.1 - 0.11 11.7 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KPI45650.1 - 0.11 13.0 0.0 8.3 6.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KPI45650.1 - 0.13 12.0 0.4 1.6 8.5 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KPI45650.1 - 0.19 11.5 0.0 17 5.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KPI45650.1 - 0.2 11.0 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 KaiC SASRP1 PF15160.6 KPI45650.1 - 0.91 9.2 8.7 0.28 10.8 5.5 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 RasGEF PF00617.19 KPI45651.1 - 3.2e-49 167.5 2.9 7.2e-49 166.4 2.9 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KPI45651.1 - 1.7e-12 47.5 0.0 9.5e-12 45.1 0.0 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KPI45651.1 - 3.7e-06 26.7 0.0 6.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KPI45651.1 - 5.4e-06 25.9 0.0 1.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain CHASE3 PF05227.13 KPI45651.1 - 0.03 14.2 0.9 0.084 12.8 0.2 2.3 2 0 0 2 2 2 0 CHASE3 domain DUF5304 PF17230.2 KPI45651.1 - 0.071 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5304) I_LWEQ PF01608.17 KPI45651.1 - 3.4 7.9 9.6 0.67 10.2 0.1 3.8 4 1 0 4 4 4 0 I/LWEQ domain tRNA-synt_1b PF00579.25 KPI45652.1 - 5.9e-70 235.9 0.0 7.8e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KPI45652.1 - 4.6e-34 116.8 0.0 8.5e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 KPI45652.1 - 0.0012 18.5 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain Polysacc_deac_1 PF01522.21 KPI45653.1 - 0.0017 18.3 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase E_Pc_C PF06752.12 KPI45653.1 - 1.3 9.1 12.4 3.4 7.7 12.4 1.7 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Epimerase PF01370.21 KPI45654.1 - 8.9e-08 31.9 0.0 1.3e-05 24.8 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI45654.1 - 0.00084 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Amino_oxidase PF01593.24 KPI45655.1 - 2.4e-55 188.7 0.0 2.7e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI45655.1 - 2e-16 59.9 0.6 4.6e-16 58.8 0.2 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI45655.1 - 4.6e-08 32.6 1.3 7.1e-08 31.9 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI45655.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI45655.1 - 2.9e-06 26.6 0.0 0.0014 17.8 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KPI45655.1 - 4e-06 26.3 0.3 6.7e-06 25.5 0.3 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KPI45655.1 - 1.6e-05 24.3 0.4 2.4e-05 23.8 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KPI45655.1 - 1.7e-05 24.4 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI45655.1 - 3.2e-05 23.3 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI45655.1 - 0.00017 20.4 0.2 0.00045 19.0 0.5 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KPI45655.1 - 0.00094 18.4 0.7 0.0016 17.6 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KPI45655.1 - 0.001 18.4 0.1 0.0055 16.0 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI45655.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KPI45655.1 - 0.017 15.7 1.3 0.052 14.1 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_polI_A34 PF08208.11 KPI45656.1 - 2.1 8.4 7.7 2.6 8.1 2.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Aldedh PF00171.22 KPI45657.1 - 1.4e-182 607.3 0.9 1.6e-182 607.1 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KPI45657.1 - 0.046 13.2 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Pkinase PF00069.25 KPI45658.1 - 7.8e-61 205.7 0.1 1.8e-54 184.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45658.1 - 5.5e-41 140.6 0.0 3.8e-39 134.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KPI45658.1 - 0.0005 19.0 1.4 0.00075 18.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KPI45658.1 - 0.061 12.6 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like HET PF06985.11 KPI45659.1 - 2.5e-22 79.8 0.0 4.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Proteasome PF00227.26 KPI45660.1 - 1.4e-27 96.4 0.0 1.7e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.18 KPI45661.1 - 0.0057 16.7 11.0 0.01 15.9 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD PF12710.7 KPI45662.1 - 2.6e-22 80.1 0.0 3.8e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KPI45662.1 - 0.00061 19.2 0.0 0.0036 16.7 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 KPI45662.1 - 0.0029 17.1 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KPI45662.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PAD_porph PF04371.15 KPI45663.1 - 2.9e-93 312.6 0.0 3.3e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 KPI45663.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase SNF2_N PF00176.23 KPI45664.1 - 3.3e-57 193.8 0.4 6.8e-57 192.8 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KPI45664.1 - 3.4e-10 39.6 9.0 8.3e-10 38.4 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI45664.1 - 1.3e-09 37.8 8.9 2.8e-09 36.7 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI45664.1 - 4.5e-08 32.8 8.0 1.1e-07 31.5 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI45664.1 - 6.8e-08 32.7 10.6 1.6e-07 31.5 10.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI45664.1 - 8.8e-07 28.9 4.3 4.5e-06 26.6 4.7 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KPI45664.1 - 1.5e-05 24.9 8.9 4.3e-05 23.4 8.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KPI45664.1 - 1.6e-05 24.7 7.1 3.8e-05 23.4 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 KPI45664.1 - 2.2e-05 24.7 0.1 5.7e-05 23.4 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KPI45664.1 - 0.00012 22.3 10.8 0.0005 20.3 10.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KPI45664.1 - 0.0014 18.7 7.9 0.0032 17.6 7.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Ndc1_Nup PF09531.10 KPI45664.1 - 0.0021 16.8 0.2 0.0034 16.2 0.2 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Baculo_IE-1 PF05290.11 KPI45664.1 - 0.031 14.2 0.3 0.072 13.0 0.3 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KPI45664.1 - 0.72 9.7 8.5 2.1 8.2 8.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PIN_8 PF18476.1 KPI45664.1 - 0.73 9.6 3.7 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 PIN like domain Zn_ribbon_17 PF17120.5 KPI45664.1 - 0.95 9.1 7.2 2.2 8.0 7.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KPI45664.1 - 0.98 9.1 6.3 2.3 7.9 6.3 1.6 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 KPI45664.1 - 2.7 8.1 5.9 7 6.8 5.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon DAO PF01266.24 KPI45665.1 - 8.1e-21 75.0 3.7 9.8e-21 74.7 3.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF3328 PF11807.8 KPI45666.1 - 2.3e-11 43.9 1.0 2.3e-11 43.9 1.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3328) Tad PF13400.6 KPI45666.1 - 0.38 11.1 1.9 0.66 10.3 1.9 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like UAF_Rrn10 PF05234.11 KPI45667.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Erv26 PF04148.13 KPI45668.1 - 2.8e-84 282.1 0.0 3.3e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 A_deaminase PF00962.22 KPI45669.1 - 4.3e-20 72.3 0.0 7.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase CBP_BcsO PF17037.5 KPI45670.1 - 9.7 6.3 15.0 31 4.6 14.8 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsO RRS1 PF04939.12 KPI45671.1 - 1.1e-42 145.6 0.2 1.4e-42 145.4 0.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SLD5_C PF16922.5 KPI45673.1 - 0.00012 22.2 0.8 0.00019 21.6 0.8 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus K_channel_TID PF07941.11 KPI45673.1 - 0.027 14.9 0.8 0.073 13.5 0.8 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Sld5 PF05916.11 KPI45673.1 - 0.061 13.8 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 GINS complex protein Cyclin_N PF00134.23 KPI45674.1 - 5.9e-37 126.2 0.4 2.1e-36 124.5 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KPI45674.1 - 5.3e-07 29.7 1.7 4.1e-06 26.9 1.7 2.3 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF2967 PF11179.8 KPI45674.1 - 0.08 11.0 0.5 0.12 10.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) ADH_zinc_N PF00107.26 KPI45676.1 - 9.6e-20 70.9 0.5 1.7e-19 70.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KPI45676.1 - 2.8e-15 57.6 0.0 5.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI45676.1 - 1.1e-09 38.1 0.1 3.8e-09 36.4 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KPI45676.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KPI45676.1 - 0.049 12.9 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YTH PF04146.15 KPI45677.1 - 1.1e-57 194.6 0.0 2e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KPI45677.1 - 6.7e-09 35.4 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.16 KPI45678.1 - 1.4e-10 41.6 0.0 3.4e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.12 KPI45678.1 - 0.07 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF5637 PF18687.1 KPI45678.1 - 0.12 12.4 1.3 0.13 12.2 0.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5637) Sugar_tr PF00083.24 KPI45679.1 - 2.6e-75 254.0 14.9 3e-75 253.8 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45679.1 - 8.8e-31 107.1 22.4 1.1e-24 87.1 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KPI45679.1 - 0.00074 18.1 2.8 0.0016 17.0 2.8 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.27 KPI45680.1 - 5.4e-27 95.0 0.1 8.5e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KPI45680.1 - 3e-05 24.0 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RecA PF00154.21 KPI45680.1 - 6.5e-05 22.5 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_29 PF13555.6 KPI45680.1 - 0.0011 18.6 0.3 0.0032 17.2 0.2 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPI45680.1 - 0.0056 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KPI45680.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 KPI45680.1 - 0.017 14.5 0.0 0.072 12.5 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KPI45680.1 - 0.05 14.1 0.0 0.093 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KPI45680.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPI45680.1 - 0.13 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KPI45680.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KPI45680.1 - 0.19 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KPI45680.1 - 0.2 11.2 0.0 0.52 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain EGF_2 PF07974.13 KPI45680.1 - 0.33 11.4 35.0 0.23 11.8 14.7 4.0 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 KPI45680.1 - 1 10.1 20.2 5.6 7.8 6.3 4.4 3 0 0 3 3 3 0 Human growth factor-like EGF E1_dh PF00676.20 KPI45681.1 - 1.3e-88 296.8 0.2 1.6e-88 296.5 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KPI45681.1 - 0.0082 15.9 0.2 0.026 14.3 0.2 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain EnY2 PF10163.9 KPI45681.1 - 0.048 14.0 0.3 0.12 12.8 0.3 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 N_methyl PF07963.12 KPI45681.1 - 0.16 11.6 0.3 0.32 10.6 0.3 1.5 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Ribosomal_S28e PF01200.18 KPI45682.1 - 3.8e-31 106.9 1.8 4.2e-31 106.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e WD40 PF00400.32 KPI45684.1 - 2e-62 205.6 32.4 4.1e-11 43.3 0.5 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI45684.1 - 4.9e-24 84.5 2.4 5e-05 23.5 0.1 6.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI45684.1 - 2.1e-13 50.0 5.4 0.02 13.9 1.5 5.9 3 3 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KPI45684.1 - 5.1e-06 25.4 7.2 0.36 9.4 0.2 5.6 3 3 3 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KPI45684.1 - 3.9e-05 22.6 0.3 0.00093 18.0 0.2 2.8 1 1 1 2 2 2 1 Nup133 N terminal like eIF2A PF08662.11 KPI45684.1 - 5.4e-05 23.1 0.0 0.35 10.7 0.0 2.9 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KPI45684.1 - 0.00037 19.9 0.6 2.1 7.6 0.0 3.7 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 KPI45684.1 - 0.00076 17.6 0.1 0.14 10.1 0.0 2.1 2 0 0 2 2 2 2 IKI3 family NLE PF08154.12 KPI45684.1 - 0.0013 19.2 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain PD40 PF07676.12 KPI45684.1 - 0.0071 16.3 2.0 1.1 9.3 0.1 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KPI45684.1 - 0.077 12.7 0.1 22 4.9 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature FAD_binding_9 PF08021.11 KPI45684.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain TFIIIC_delta PF12657.7 KPI45684.1 - 0.12 12.3 4.3 27 4.6 0.0 4.7 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PALB2_WD40 PF16756.5 KPI45684.1 - 0.13 11.2 1.4 3.7 6.4 0.3 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Gmad1 PF10647.9 KPI45684.1 - 0.29 10.9 4.0 3.2 7.4 0.4 3.1 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain PCI PF01399.27 KPI45685.1 - 5.2e-11 43.0 0.0 9.1e-10 39.0 0.0 2.7 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KPI45685.1 - 1.9e-09 37.0 3.8 4.4e-09 35.9 3.8 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Wbp11 PF09429.10 KPI45685.1 - 0.01 16.2 0.8 0.026 14.9 0.8 1.6 1 0 0 1 1 1 0 WW domain binding protein 11 GRP PF07172.11 KPI45685.1 - 1.8 9.3 11.4 4.3 8.1 11.4 1.6 1 0 0 1 1 1 0 Glycine rich protein family FmiP_Thoc5 PF09766.9 KPI45686.1 - 4e-26 92.2 11.0 4e-26 92.2 11.0 1.4 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 zf-CpG_bind_C PF12269.8 KPI45686.1 - 1.5 8.5 7.0 3.1 7.5 3.0 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Casc1_N PF15927.5 KPI45686.1 - 9 5.9 16.4 0.58 9.8 9.6 2.1 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus CFEM PF05730.11 KPI45687.1 - 1.5e-08 34.6 15.2 4.4e-08 33.1 15.2 1.8 1 0 0 1 1 1 1 CFEM domain DUF523 PF04463.12 KPI45687.1 - 0.0055 16.7 0.6 0.0078 16.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF523) TIL PF01826.17 KPI45687.1 - 0.4 11.0 9.4 0.39 11.0 8.2 1.6 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain KAR9 PF08580.10 KPI45687.1 - 0.52 8.8 2.9 0.59 8.6 2.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CC190 PF15768.5 KPI45687.1 - 3 7.9 7.1 3.7 7.5 7.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Miga PF10265.9 KPI45687.1 - 3.9 6.3 6.2 4.6 6.1 6.2 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 KPI45687.1 - 5.6 5.4 7.8 6.1 5.3 7.8 1.1 1 0 0 1 1 1 0 Macoilin family Formyl_trans_N PF00551.19 KPI45688.1 - 2.3e-41 141.5 0.1 3e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase MoaE PF02391.17 KPI45688.1 - 0.039 14.2 0.2 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 MoaE protein LpxI_C PF06230.11 KPI45688.1 - 0.1 12.4 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 LpxI C-terminal domain Pyr_redox_2 PF07992.14 KPI45689.1 - 1.5e-14 53.9 0.0 2.1e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KPI45689.1 - 2.4e-13 49.3 0.0 4.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KPI45689.1 - 6.5e-13 48.7 0.0 2.5e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI45689.1 - 4.8e-08 32.6 0.0 8.6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KPI45689.1 - 1.1e-07 31.2 0.1 0.00018 20.7 0.0 3.0 2 1 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 KPI45689.1 - 1.3e-06 27.8 0.0 6.3e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KPI45689.1 - 8.1e-06 26.3 0.3 0.055 14.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI45689.1 - 0.00015 21.0 0.0 0.0027 16.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KPI45689.1 - 0.00021 21.0 0.2 0.0044 16.7 0.0 2.6 3 0 0 3 3 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KPI45689.1 - 0.00026 21.0 0.1 0.13 12.3 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KPI45689.1 - 0.0028 18.1 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KPI45689.1 - 0.005 16.8 0.0 0.15 11.9 0.0 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KPI45689.1 - 0.0096 15.6 0.6 3.9 7.1 0.2 2.7 3 1 0 3 3 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KPI45689.1 - 0.015 15.4 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KPI45689.1 - 0.022 13.5 0.9 2.8 6.5 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KPI45689.1 - 0.033 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KPI45689.1 - 0.058 12.7 0.1 9.7 5.5 0.0 2.5 2 0 0 2 2 2 0 ThiF family NAD_binding_2 PF03446.15 KPI45689.1 - 0.092 12.9 0.0 0.64 10.2 0.0 2.4 4 0 0 4 4 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 KPI45689.1 - 0.098 11.7 0.8 24 3.9 0.1 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 KPI45689.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KPI45689.1 - 0.17 12.1 0.3 26 5.1 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_3 PF01494.19 KPI45689.1 - 0.18 11.0 1.1 0.82 8.9 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain DUF1188 PF06690.11 KPI45689.1 - 0.23 11.0 0.0 18 4.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1188) Thi4 PF01946.17 KPI45689.1 - 0.25 10.5 0.2 7.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.16 KPI45690.1 - 1.8e-39 135.7 47.9 1.8e-39 135.7 47.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI45690.1 - 3.4e-08 32.4 12.1 3.4e-08 32.4 12.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KPI45690.1 - 7.3e-06 25.1 14.8 7.3e-06 25.1 14.8 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter Neisseria_TspB PF05616.13 KPI45690.1 - 9 4.6 5.5 14 4.0 5.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein eIF2A PF08662.11 KPI45692.1 - 3.4e-40 138.0 3.7 8.1e-36 123.7 1.3 3.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KPI45692.1 - 1.3e-07 31.4 0.0 2.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KPI45692.1 - 0.066 14.1 1.0 1.1e+02 3.9 0.0 4.5 4 1 0 4 4 4 0 WD domain, G-beta repeat p450 PF00067.22 KPI45693.1 - 6.6e-72 242.7 0.0 8.2e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KPI45693.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split PT-TG PF14449.6 KPI45693.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Pre-toxin TG Vsr PF03852.15 KPI45695.1 - 0.12 12.3 1.2 6.9 6.6 0.1 3.7 2 2 3 5 5 5 0 DNA mismatch endonuclease Vsr Foie-gras_1 PF11817.8 KPI45695.1 - 0.52 9.9 3.2 0.65 9.5 3.2 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 MSA_2 PF00985.17 KPI45695.1 - 1 9.7 3.7 1.4 9.3 3.7 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family HD PF01966.22 KPI45696.1 - 0.00037 20.7 0.1 0.00074 19.7 0.1 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 KPI45696.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Sugar_tr PF00083.24 KPI45697.1 - 5.8e-86 289.1 19.6 6.6e-86 288.9 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45697.1 - 9.8e-25 87.2 36.1 1.3e-22 80.2 26.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KPI45697.1 - 0.00024 19.8 3.2 0.00024 19.8 3.2 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein CoA_binding PF02629.19 KPI45698.1 - 1.3e-21 77.1 0.4 2.9e-21 75.9 0.4 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KPI45698.1 - 9e-19 67.8 0.5 9e-19 67.8 0.5 2.1 3 0 0 3 3 3 1 CoA-ligase Succ_CoA_lig PF13607.6 KPI45698.1 - 1e-09 38.3 0.1 2e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain p450 PF00067.22 KPI45699.1 - 1.2e-53 182.5 0.0 2.7e-53 181.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 HCR PF07111.12 KPI45701.1 - 0.078 11.0 2.0 0.092 10.8 2.0 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) MT0933_antitox PF14013.6 KPI45701.1 - 3.4 8.0 7.7 0.53 10.6 2.7 2.3 2 2 0 2 2 2 0 MT0933-like antitoxin protein DDHD PF02862.17 KPI45702.1 - 8.4e-54 183.1 4.1 8.1e-53 179.9 0.0 2.8 2 1 0 2 2 2 1 DDHD domain CBM39 PF15886.5 KPI45702.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Cutinase PF01083.22 KPI45703.1 - 2.8e-48 164.2 0.1 3.3e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KPI45703.1 - 0.005 16.4 0.2 0.0081 15.7 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KPI45703.1 - 0.024 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KPI45703.1 - 0.029 14.2 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KPI45703.1 - 0.065 12.8 0.1 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KPI45703.1 - 0.14 11.3 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 KPI45704.1 - 4.7e-59 200.3 0.0 6e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrolase_4 PF12146.8 KPI45705.1 - 3.7e-17 62.4 0.0 3.4e-11 42.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KPI45705.1 - 2e-12 47.3 0.0 8.9e-08 32.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KPI45705.1 - 8.2e-09 34.6 0.0 0.033 12.9 0.1 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KPI45705.1 - 1e-07 32.8 0.0 1.8e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KPI45705.1 - 6.9e-06 25.9 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KPI45705.1 - 2.6e-05 24.2 0.0 6.6e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KPI45705.1 - 0.00029 20.8 0.0 0.0083 16.1 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 KPI45705.1 - 0.00049 19.2 0.0 0.00062 18.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KPI45705.1 - 0.0034 16.9 0.0 0.016 14.7 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KPI45705.1 - 0.01 15.4 0.1 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DLH PF01738.18 KPI45705.1 - 0.012 15.2 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KPI45705.1 - 0.017 14.9 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KPI45705.1 - 0.041 13.5 0.1 3.5 7.1 0.1 2.3 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 KPI45705.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KPI45705.1 - 0.16 11.8 0.1 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) LSM PF01423.22 KPI45706.1 - 2.9e-20 71.7 0.0 3.7e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain adh_short PF00106.25 KPI45707.1 - 4.4e-37 127.4 0.0 5.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45707.1 - 1.1e-20 74.2 0.0 1.4e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45707.1 - 1.8e-08 34.5 0.0 5.1e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI45707.1 - 4e-06 26.5 0.0 8.9e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KPI45707.1 - 0.00046 19.6 0.1 0.00069 19.1 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KPI45707.1 - 0.014 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TrbI_Ftype PF09677.10 KPI45707.1 - 0.031 14.6 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Shikimate_DH PF01488.20 KPI45707.1 - 0.039 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 KPI45707.1 - 0.073 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 KPI45707.1 - 0.082 13.2 0.1 0.16 12.2 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KPI45707.1 - 0.085 11.9 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 KPI45707.1 - 0.09 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HET PF06985.11 KPI45708.1 - 2.2e-28 99.4 0.0 4.4e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Stk19 PF10494.9 KPI45709.1 - 1.8e-63 214.5 0.0 1.9e-42 145.7 0.0 2.1 1 1 1 2 2 2 2 Serine-threonine protein kinase 19 Sugar_tr PF00083.24 KPI45710.1 - 2.5e-77 260.7 17.0 3.1e-77 260.4 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45710.1 - 1.2e-20 73.8 63.7 3.5e-18 65.7 30.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KPI45710.1 - 1.4e-05 24.5 5.0 1.4e-05 24.5 5.0 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Lig_chan PF00060.26 KPI45710.1 - 0.0092 15.8 0.7 0.034 14.0 0.7 1.9 1 0 0 1 1 1 1 Ligand-gated ion channel MFS_1_like PF12832.7 KPI45710.1 - 0.036 12.9 13.7 0.015 14.2 2.2 2.4 2 1 0 2 2 2 0 MFS_1 like family VIT1 PF01988.19 KPI45710.1 - 0.045 13.6 0.1 0.045 13.6 0.1 2.3 2 0 0 2 2 2 0 VIT family SGL PF08450.12 KPI45711.1 - 1.9e-22 80.1 0.1 3.1e-21 76.1 0.1 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KPI45711.1 - 0.0014 18.7 0.0 0.0061 16.6 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase PD40 PF07676.12 KPI45711.1 - 0.0032 17.4 0.8 0.0083 16.0 0.3 2.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KPI45711.1 - 1.4 9.5 10.4 0.23 12.0 0.5 4.1 4 1 0 4 4 4 0 PQQ-like domain Polyketide_cyc PF03364.20 KPI45712.1 - 1.4e-10 41.4 0.0 1.7e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Abhydrolase_2 PF02230.16 KPI45713.1 - 1.6e-30 106.6 0.0 1.1e-21 77.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 KPI45713.1 - 0.00047 19.9 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KPI45713.1 - 0.054 14.1 0.2 0.11 13.1 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ATP11 PF06644.11 KPI45714.1 - 8.6e-95 317.6 0.0 1e-94 317.4 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein Proteasome PF00227.26 KPI45718.1 - 7.7e-41 139.7 0.0 9.5e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.18 KPI45720.1 - 7.2e-28 97.7 0.0 1.6e-27 96.6 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KPI45720.1 - 6.1e-09 34.7 0.3 7.6e-09 34.4 0.3 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation Metal_resist PF13801.6 KPI45720.1 - 0.069 13.4 5.3 4.1 7.6 0.5 3.4 3 0 0 3 3 3 0 Heavy-metal resistance Upf2 PF04050.14 KPI45720.1 - 1.3 9.8 5.8 2.7 8.7 3.3 2.2 1 1 1 2 2 2 0 Up-frameshift suppressor 2 AAA PF00004.29 KPI45721.1 - 2.6e-14 53.8 0.0 4.6e-06 27.1 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KPI45721.1 - 7.3e-10 39.1 0.1 7.3e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 BCS1 N terminal RuvB_N PF05496.12 KPI45721.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KPI45721.1 - 0.0061 16.7 0.0 0.023 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KPI45721.1 - 0.011 16.1 0.1 0.056 13.8 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KPI45721.1 - 0.011 16.0 0.0 0.48 10.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KPI45721.1 - 0.02 14.6 2.5 2.4 7.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KPI45721.1 - 0.022 15.3 0.1 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KPI45721.1 - 0.04 14.2 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KPI45721.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KPI45721.1 - 0.1 11.6 0.0 2.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 KPI45721.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 KPI45721.1 - 0.15 12.5 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KPI45721.1 - 0.16 12.5 0.9 2.2 8.8 0.1 3.1 3 1 0 3 3 3 0 ABC transporter AAA_11 PF13086.6 KPI45721.1 - 3.9 7.2 6.3 0.63 9.8 0.8 2.5 3 1 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 KPI45721.1 - 5.7 7.2 6.1 8 6.7 0.1 3.2 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain zf-MYND PF01753.18 KPI45722.1 - 6.8e-06 26.1 18.6 1.3e-05 25.2 18.6 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KPI45722.1 - 1.4 9.3 12.0 2.7 8.4 12.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Complex1_LYR PF05347.15 KPI45723.1 - 1.2e-12 47.7 0.8 3e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KPI45723.1 - 0.13 13.0 1.3 0.45 11.3 1.3 1.8 1 1 0 1 1 1 0 Complex1_LYR-like Phage_TAC_11 PF11836.8 KPI45723.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 FAD_binding_3 PF01494.19 KPI45725.1 - 2.6e-16 59.8 0.0 6.5e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI45725.1 - 5.1e-08 32.9 0.3 9.4e-05 22.1 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KPI45725.1 - 1.1e-07 31.4 0.9 0.00016 21.1 0.2 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI45725.1 - 3.7e-06 27.1 0.3 1e-05 25.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KPI45725.1 - 4.6e-05 22.7 0.7 0.00013 21.2 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KPI45725.1 - 0.00012 21.3 0.2 0.00019 20.6 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KPI45725.1 - 0.0019 17.0 0.1 0.089 11.5 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KPI45725.1 - 0.034 13.5 0.6 0.23 10.7 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KPI45725.1 - 0.051 14.1 0.0 0.24 12.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAP PF07174.11 KPI45726.1 - 7.9 5.8 27.1 8.6 5.7 27.1 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Lyase_1 PF00206.20 KPI45728.1 - 8.3e-91 304.6 0.0 1.4e-90 303.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KPI45728.1 - 3.6e-17 62.5 0.9 6.1e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 Fumarase C C-terminus adh_short PF00106.25 KPI45729.1 - 7.2e-47 159.4 0.0 8.4e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45729.1 - 7.9e-34 117.2 0.0 9.8e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45729.1 - 1.4e-11 44.7 0.1 1.7e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KPI45729.1 - 0.012 15.1 0.2 0.031 13.7 0.1 1.7 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KPI45729.1 - 0.12 11.7 0.2 1.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KPI45729.1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_17 PF13431.6 KPI45731.1 - 0.0025 18.1 0.2 0.041 14.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat CCDC92 PF14916.6 KPI45731.1 - 0.041 13.7 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Fungal_trans PF04082.18 KPI45732.1 - 8.1e-15 54.6 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Plasmid_RAQPRD PF09686.10 KPI45732.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Methyltransf_23 PF13489.6 KPI45733.1 - 5.9e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI45733.1 - 4e-10 40.3 0.0 1e-09 39.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45733.1 - 8.1e-09 36.1 0.0 1.8e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45733.1 - 2.3e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI45733.1 - 0.00029 21.4 0.0 0.00085 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 KPI45733.1 - 0.0036 16.8 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KPI45733.1 - 0.018 14.5 0.0 0.062 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase SUI1 PF01253.22 KPI45734.1 - 1.1e-20 73.9 2.3 2e-20 73.1 2.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2717 PF10911.8 KPI45734.1 - 0.051 13.3 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) Thiamine_BP PF01910.17 KPI45734.1 - 0.055 13.4 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 Thiamine-binding protein Ocnus PF05005.15 KPI45734.1 - 0.087 13.0 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) XET_C PF06955.12 KPI45735.1 - 0.45 10.4 1.7 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus WD40 PF00400.32 KPI45736.1 - 4.8e-49 163.3 21.9 1.5e-05 25.6 1.7 12.2 11 1 0 11 11 11 8 WD domain, G-beta repeat Utp13 PF08625.11 KPI45736.1 - 2.4e-46 157.2 1.2 2.4e-46 157.2 1.2 1.7 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KPI45736.1 - 5.1e-11 42.7 1.6 0.11 12.8 0.0 6.7 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI45736.1 - 0.00012 20.9 14.6 0.14 10.8 0.0 6.2 3 3 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KPI45736.1 - 0.006 15.6 1.4 6.4 5.6 0.0 4.6 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KPI45736.1 - 0.0069 15.2 4.6 9 4.9 0.4 5.5 4 1 2 6 6 6 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KPI45736.1 - 0.023 13.3 0.0 0.78 8.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 KPI45736.1 - 0.11 11.5 0.0 0.33 9.9 0.0 1.7 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain DUF4381 PF14316.6 KPI45737.1 - 0.098 12.9 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YajC PF02699.15 KPI45737.1 - 0.2 11.6 0.1 0.37 10.7 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Ras PF00071.22 KPI45738.1 - 1.4e-59 200.3 0.5 1.6e-59 200.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KPI45738.1 - 8.9e-37 126.0 0.3 2e-36 124.8 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KPI45738.1 - 2.8e-15 56.2 0.0 3.4e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KPI45738.1 - 1.3e-07 31.3 0.1 1.9e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KPI45738.1 - 9.7e-07 28.4 0.1 1.2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KPI45738.1 - 2.3e-06 27.7 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI45738.1 - 2.6e-05 24.2 1.7 0.096 12.6 0.3 2.4 1 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KPI45738.1 - 0.013 15.9 0.1 0.026 14.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KPI45738.1 - 0.032 14.5 0.1 3 8.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain DUF2624 PF11116.8 KPI45738.1 - 0.039 14.8 0.6 0.14 13.0 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) adh_short_C2 PF13561.6 KPI45739.1 - 1.7e-40 139.1 0.5 1.1e-39 136.4 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI45739.1 - 4e-36 124.3 0.1 7.5e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KPI45739.1 - 1.5e-07 31.5 1.2 2.9e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KPI45739.1 - 0.0013 18.3 0.1 0.47 9.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sod_Fe_C PF02777.18 KPI45740.1 - 4.1e-19 68.6 2.5 1.8e-10 40.9 0.2 2.8 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KPI45740.1 - 0.18 12.3 2.8 0.41 11.1 2.8 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain CCDC24 PF15669.5 KPI45741.1 - 0.52 10.1 2.2 0.59 10.0 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Period_C PF12114.8 KPI45741.1 - 4 7.0 11.7 7.5 6.1 11.7 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pkinase PF00069.25 KPI45742.1 - 3.8e-10 39.6 0.0 6.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KPI45742.1 - 1.5e-08 34.2 0.3 0.12 12.7 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KPI45742.1 - 2.7e-06 27.7 1.1 0.00032 21.0 0.3 3.5 2 1 2 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KPI45742.1 - 9.2e-06 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KPI45742.1 - 2.2e-05 24.6 0.4 0.0033 17.5 0.0 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KPI45742.1 - 0.0033 17.9 0.6 7.4 7.2 0.0 3.7 2 1 1 3 3 3 1 HEAT-like repeat CLASP_N PF12348.8 KPI45742.1 - 0.0094 15.5 0.1 0.28 10.7 0.0 2.6 1 1 0 2 2 2 1 CLASP N terminal Kinase-like PF14531.6 KPI45742.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.20 KPI45742.1 - 0.21 10.1 0.0 1.3 7.5 0.1 1.9 1 1 0 2 2 2 0 Adaptin N terminal region Fungal_trans_2 PF11951.8 KPI45743.1 - 0.044 12.6 0.2 0.073 11.9 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain GSDH PF07995.11 KPI45744.1 - 0.0017 17.7 2.3 0.0081 15.5 1.8 2.3 1 1 1 2 2 2 2 Glucose / Sorbosone dehydrogenase NHL PF01436.21 KPI45744.1 - 0.0035 17.3 0.0 0.027 14.5 0.0 2.7 2 0 0 2 2 2 1 NHL repeat SBBP PF06739.11 KPI45744.1 - 0.051 13.6 0.1 5.2 7.2 0.0 3.4 4 0 0 4 4 4 0 Beta-propeller repeat RHS_repeat PF05593.14 KPI45744.1 - 0.13 12.8 1.2 3 8.5 0.1 3.1 2 0 0 2 2 2 0 RHS Repeat CDC27 PF09507.10 KPI45745.1 - 1.6 8.0 4.7 3.1 7.1 4.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glycos_transf_1 PF00534.20 KPI45746.1 - 3.4e-22 78.8 0.0 7.3e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KPI45746.1 - 8.3e-17 61.9 0.2 1.5e-16 61.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KPI45746.1 - 7.8e-12 45.5 0.6 1.9e-11 44.3 0.6 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KPI45746.1 - 5.5e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KPI45746.1 - 0.00083 19.8 4.5 0.00083 19.8 4.5 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Aminotran_4 PF01063.19 KPI45747.1 - 8e-21 74.9 0.0 1.8e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 KPI45748.1 - 1.3e-68 231.9 0.0 1.5e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4110 PF13422.6 KPI45749.1 - 4.3e-30 103.6 3.4 4.3e-30 103.6 3.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KPI45749.1 - 1.3e-29 101.9 8.6 4.3e-08 33.0 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KPI45749.1 - 1.2e-26 92.4 14.8 6.2e-09 35.9 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KPI45749.1 - 1.4e-23 82.4 1.3 1.8e-06 27.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KPI45749.1 - 2.9e-23 81.3 3.7 3.2e-05 24.1 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KPI45749.1 - 5.3e-18 64.3 0.5 7.6e-09 35.0 0.1 4.9 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KPI45749.1 - 7e-18 63.8 8.4 1.2e-06 28.3 0.2 6.1 6 1 0 6 6 6 4 Kelch motif BUD22 PF09073.10 KPI45749.1 - 0.0053 16.2 2.6 0.0053 16.2 2.6 2.4 2 0 0 2 2 2 1 BUD22 GEMIN8 PF15348.6 KPI45749.1 - 1.7 8.9 13.2 1.2 9.4 2.7 2.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Ribosomal_S18 PF01084.20 KPI45750.1 - 7.4e-16 58.1 0.8 2.3e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S18 Nuc_deoxyri_tr2 PF15891.5 KPI45751.1 - 4.6e-21 75.2 0.0 6.8e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like FAD_binding_3 PF01494.19 KPI45752.1 - 1.2e-25 90.6 0.8 5.4e-25 88.4 0.8 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI45752.1 - 2.8e-10 40.3 1.3 0.00018 21.2 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KPI45752.1 - 2.4e-05 23.6 0.6 0.00013 21.1 0.6 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KPI45752.1 - 3.3e-05 23.3 2.3 0.022 14.0 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KPI45752.1 - 4.8e-05 22.5 0.0 0.0019 17.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KPI45752.1 - 0.0022 18.2 0.0 0.0065 16.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KPI45752.1 - 0.017 15.6 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI45752.1 - 0.03 13.4 0.7 1.3 8.0 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Lipase_3 PF01764.25 KPI45753.1 - 8.4e-21 74.3 0.0 1.2e-18 67.3 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KPI45753.1 - 0.00039 19.8 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KPI45753.1 - 0.00055 20.1 0.0 0.00091 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KPI45753.1 - 0.0061 16.2 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KPI45753.1 - 0.0093 16.6 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KPI45753.1 - 0.0096 15.6 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KPI45753.1 - 0.019 14.5 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 KPI45753.1 - 0.13 12.0 0.1 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein 3Beta_HSD PF01073.19 KPI45754.1 - 9.3e-49 165.9 0.0 1.1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KPI45754.1 - 9.2e-26 90.8 0.2 1.1e-25 90.5 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KPI45754.1 - 1.4e-12 47.7 0.0 4.4e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KPI45754.1 - 1.7e-12 47.0 0.0 3e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KPI45754.1 - 5.2e-11 42.2 0.2 8e-08 31.8 0.1 2.2 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KPI45754.1 - 2.2e-06 27.7 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KPI45754.1 - 0.0011 18.2 0.3 0.0038 16.4 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KPI45754.1 - 0.0092 15.9 0.3 0.023 14.6 0.3 1.7 1 1 0 1 1 1 1 KR domain ABC_membrane PF00664.23 KPI45755.1 - 2.2e-70 237.5 25.8 1.2e-35 123.5 9.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KPI45755.1 - 1.6e-60 203.6 0.0 3.3e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI45755.1 - 6.5e-16 58.4 0.5 7.7e-07 28.8 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KPI45755.1 - 1.2e-08 34.6 1.8 0.003 17.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KPI45755.1 - 6.3e-08 33.0 1.1 0.0087 16.3 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KPI45755.1 - 1.8e-07 31.7 2.7 0.0053 17.2 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 KPI45755.1 - 2.4e-07 30.9 1.4 0.26 11.1 0.1 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KPI45755.1 - 4.9e-07 30.4 0.7 0.036 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KPI45755.1 - 2.2e-06 27.7 0.1 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KPI45755.1 - 4.8e-05 22.4 1.4 3.1 6.5 0.1 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_33 PF13671.6 KPI45755.1 - 5e-05 23.5 0.0 0.29 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KPI45755.1 - 0.00015 22.3 0.0 0.85 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KPI45755.1 - 0.00023 21.0 0.7 0.092 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KPI45755.1 - 0.00026 20.6 0.3 0.048 13.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KPI45755.1 - 0.00046 20.0 1.6 1.3 8.7 0.0 3.4 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KPI45755.1 - 0.00053 20.1 0.4 0.68 10.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF3987 PF13148.6 KPI45755.1 - 0.00066 18.8 0.0 0.68 8.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Mg_chelatase PF01078.21 KPI45755.1 - 0.00075 18.9 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPI45755.1 - 0.0012 18.8 1.0 1.8 8.6 0.0 4.3 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KPI45755.1 - 0.0034 16.6 0.1 0.99 8.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KPI45755.1 - 0.011 15.0 0.1 0.77 9.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KPI45755.1 - 0.012 16.0 0.1 8.9 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KPI45755.1 - 0.015 15.4 5.1 0.8 9.8 0.5 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain APS_kinase PF01583.20 KPI45755.1 - 0.018 14.9 0.3 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 KPI45755.1 - 0.018 14.7 0.5 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KPI45755.1 - 0.028 14.6 0.0 4.9 7.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 KPI45755.1 - 0.03 13.4 0.3 0.66 9.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KPI45755.1 - 0.031 14.2 0.1 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KPI45755.1 - 0.037 13.5 0.5 7.8 5.9 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein Ploopntkinase3 PF18751.1 KPI45755.1 - 0.043 13.7 0.3 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATPase PF06745.13 KPI45755.1 - 0.059 12.7 0.8 3.7 6.8 0.1 2.6 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 KPI45755.1 - 0.06 13.0 0.0 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 KPI45755.1 - 0.065 13.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 KPI45755.1 - 0.11 12.6 0.0 5.9 7.0 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_lid_7 PF17867.1 KPI45755.1 - 0.11 12.7 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 1 0 Midasin AAA lid domain AAA_28 PF13521.6 KPI45755.1 - 0.13 12.5 0.2 7.6 6.7 0.1 2.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KPI45755.1 - 0.13 12.0 0.4 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 KPI45755.1 - 0.14 11.0 0.8 18 4.1 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Guanylate_kin PF00625.21 KPI45755.1 - 0.2 11.3 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase Gtr1_RagA PF04670.12 KPI45755.1 - 0.21 10.9 0.5 5.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_13 PF13166.6 KPI45755.1 - 0.42 9.2 1.0 2.2 6.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.12 KPI45756.1 - 0.00041 20.4 6.8 0.00041 20.4 6.8 2.4 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KPI45756.1 - 0.0065 16.0 17.1 0.012 15.2 17.1 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 EspB_PE PF18625.1 KPI45756.1 - 0.032 14.7 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Amidase_3 PF01520.18 KPI45756.1 - 0.12 12.5 1.9 0.22 11.6 1.9 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF724 PF05266.14 KPI45756.1 - 0.12 12.2 7.4 0.25 11.1 7.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 KPI45756.1 - 0.21 11.8 12.1 0.26 11.5 6.6 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 KPI45756.1 - 0.27 11.4 19.2 0.76 10.0 18.9 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 KPI45756.1 - 0.32 10.3 17.5 0.26 10.6 11.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KPI45756.1 - 0.42 11.2 17.7 0.61 10.6 16.3 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KPI45756.1 - 1.5 7.6 15.4 2.4 7.0 15.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2937 PF11157.8 KPI45756.1 - 1.8 8.3 4.8 3.4 7.4 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) LMBR1 PF04791.16 KPI45756.1 - 3.4 6.5 6.1 5.1 5.9 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 KPI45756.1 - 3.4 6.2 5.9 5 5.6 5.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KPI45756.1 - 4.2 6.7 11.1 7 5.9 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KPI45756.1 - 7.3 6.8 17.9 0.3 11.3 6.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KPI45756.1 - 8.7 6.5 15.2 1.8 8.7 11.1 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Peptidase_M48_N PF16491.5 KPI45757.1 - 8.2e-67 224.6 10.3 8.2e-67 224.6 10.3 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KPI45757.1 - 2.8e-48 164.3 0.0 4.9e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KPI45757.1 - 0.00097 18.4 0.6 0.0054 16.0 0.2 2.1 2 0 0 2 2 2 1 BlaR1 peptidase M56 Acetyltransf_1 PF00583.25 KPI45758.1 - 0.00031 21.0 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KPI45758.1 - 0.046 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KPI45758.1 - 0.061 13.8 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.6 KPI45759.1 - 2.3e-05 24.3 0.0 8.3e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KPI45759.1 - 0.0035 16.5 0.0 0.012 14.8 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KPI45759.1 - 0.0085 15.1 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3074 PF11274.8 KPI45760.1 - 7.9e-35 120.5 0.0 1.2e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Zn_clus PF00172.18 KPI45762.1 - 1.2e-07 31.7 12.8 2.7e-07 30.6 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 KPI45762.1 - 1.2e-06 28.6 3.2 1.2e-06 28.6 3.2 2.1 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.24 KPI45762.1 - 0.00019 21.0 10.5 0.095 12.5 4.3 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KPI45762.1 - 0.0076 16.0 9.8 0.059 13.1 4.5 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 KPI45763.1 - 4.1e-28 98.3 46.6 4.1e-28 98.3 46.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3433 PF11915.8 KPI45764.1 - 0.053 14.0 0.5 0.17 12.4 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Glyco_transf_11 PF01531.16 KPI45764.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 SYF2 PF08231.12 KPI45766.1 - 6.8e-43 146.8 9.0 6.8e-43 146.8 9.0 1.8 1 1 0 1 1 1 1 SYF2 splicing factor TetR_C_24 PF17932.1 KPI45766.1 - 0.059 13.6 0.9 5.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Far-17a_AIG1 PF04750.14 KPI45767.1 - 9.8e-55 185.0 9.3 1.1e-54 184.8 9.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3176 PF11374.8 KPI45768.1 - 1.6e-32 111.9 2.9 3e-32 111.0 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Aldose_epim PF01263.20 KPI45770.1 - 4.3e-40 137.9 0.0 4.8e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PPTA PF01239.22 KPI45772.1 - 3.4e-36 121.9 25.1 7.7e-08 31.8 0.1 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 KPI45772.1 - 8.8 6.1 17.2 5.3 6.8 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4219) Abhydrolase_1 PF00561.20 KPI45773.1 - 1.3e-20 74.2 0.1 8.3e-17 61.7 0.2 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KPI45773.1 - 6e-14 51.9 0.0 2.1e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KPI45773.1 - 2.1e-10 41.6 0.0 2.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KPI45773.1 - 0.0056 16.2 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KPI45773.1 - 0.0074 16.1 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KPI45773.1 - 0.046 13.8 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 KPI45773.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KPI45773.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Glyoxalase PF00903.25 KPI45774.1 - 3.7e-06 27.1 0.3 7.2e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KPI45774.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Fungal_trans PF04082.18 KPI45774.1 - 0.029 13.4 0.0 0.063 12.3 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cullin PF00888.22 KPI45775.1 - 1.2e-177 592.3 11.2 1.2e-177 592.3 11.2 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KPI45775.1 - 4.3e-28 97.1 1.4 1.8e-27 95.1 1.4 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain CEP170_C PF15308.6 KPI45775.1 - 0.072 11.6 0.5 0.12 10.9 0.5 1.2 1 0 0 1 1 1 0 CEP170 C-terminus Nucleoporin2 PF04096.14 KPI45775.1 - 1 9.5 3.8 0.32 11.1 0.3 2.0 2 0 0 2 2 2 0 Nucleoporin autopeptidase DivIVA PF05103.13 KPI45776.1 - 0.077 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 DivIVA protein Macoilin PF09726.9 KPI45776.1 - 6.8 5.1 9.0 7 5.1 9.0 1.1 1 0 0 1 1 1 0 Macoilin family Rif1_N PF12231.8 KPI45777.1 - 6.1e-53 180.1 0.1 9.2e-53 179.6 0.1 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal SNF2_N PF00176.23 KPI45778.1 - 7.4e-52 176.2 0.2 3e-50 170.9 0.0 2.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KPI45778.1 - 2e-17 63.5 0.0 8.3e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI45778.1 - 3.2e-06 27.3 0.0 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KPI45778.1 - 6.3e-05 22.8 10.7 6.3e-05 22.8 10.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KPI45778.1 - 0.00012 21.1 0.2 0.00048 19.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 KPI45778.1 - 0.0072 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Zn_Tnp_IS91 PF14319.6 KPI45778.1 - 3.7 7.6 16.8 0.86 9.7 4.1 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain zf_C2H2_ZHX PF18387.1 KPI45779.1 - 0.0014 18.3 0.4 0.011 15.4 0.3 2.4 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 KPI45779.1 - 0.004 17.9 5.4 1.9 9.5 0.7 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KPI45779.1 - 0.029 14.8 1.0 0.029 14.8 1.0 4.1 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KPI45779.1 - 0.32 11.1 3.0 0.34 11.0 1.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger KH_8 PF17903.1 KPI45781.1 - 4.6e-05 23.4 0.0 0.00013 22.0 0.0 1.6 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KPI45781.1 - 0.027 14.3 0.5 0.055 13.3 0.5 1.5 1 0 0 1 1 1 0 KH domain FMO-like PF00743.19 KPI45783.1 - 3.2e-23 82.0 0.0 2.9e-07 29.3 0.1 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KPI45783.1 - 2.7e-11 43.7 2.4 1.6e-05 24.9 0.2 3.7 3 1 0 3 3 3 3 FAD-NAD(P)-binding DAO PF01266.24 KPI45783.1 - 5.1e-09 36.2 0.7 3.5e-08 33.4 1.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI45783.1 - 1e-08 34.8 0.0 0.026 13.8 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KPI45783.1 - 4e-08 32.8 0.0 8e-07 28.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KPI45783.1 - 8.3e-08 31.9 0.0 0.003 16.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI45783.1 - 2e-07 31.1 0.0 5.7e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI45783.1 - 7e-06 25.6 0.1 6.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KPI45783.1 - 5.4e-05 22.5 0.7 0.13 11.4 0.1 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KPI45783.1 - 0.00027 20.3 0.2 0.00046 19.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KPI45783.1 - 0.0009 18.0 0.5 0.0028 16.4 0.5 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KPI45783.1 - 0.001 18.2 0.1 0.003 16.7 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KPI45783.1 - 0.0056 17.2 1.1 0.011 16.3 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KPI45783.1 - 0.0062 15.7 0.1 0.02 14.0 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KPI45783.1 - 0.022 14.7 0.2 0.047 13.6 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KPI45783.1 - 0.027 13.7 0.2 0.061 12.6 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KPI45783.1 - 0.03 13.6 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2059 PF09832.9 KPI45784.1 - 0.0085 16.1 1.4 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2059) AF-4 PF05110.13 KPI45784.1 - 5.1 5.1 14.8 8.1 4.4 14.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Methyltransf_25 PF13649.6 KPI45785.1 - 9.7e-15 55.1 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KPI45785.1 - 7.6e-14 52.3 0.0 1.8e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI45785.1 - 9.9e-14 51.5 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KPI45785.1 - 2.7e-13 50.4 0.0 4.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45785.1 - 2e-09 37.4 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KPI45785.1 - 7.2e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KPI45785.1 - 7.5e-05 22.0 0.0 0.026 13.7 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Roc PF08477.13 KPI45785.1 - 0.00025 21.2 1.3 0.14 12.4 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase CMAS PF02353.20 KPI45785.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KPI45785.1 - 0.0035 16.9 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KPI45785.1 - 0.0045 18.0 0.0 0.0091 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KPI45785.1 - 0.0084 15.8 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KPI45785.1 - 0.019 14.8 0.0 0.15 11.9 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase TPMT PF05724.11 KPI45785.1 - 0.036 13.7 0.1 0.083 12.5 0.1 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 KPI45785.1 - 0.058 13.1 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 KPI45785.1 - 0.06 12.7 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1640 PF07798.11 KPI45787.1 - 1.9e-45 155.1 13.0 2.7e-45 154.6 13.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF384 PF04064.13 KPI45787.1 - 0.069 13.0 0.3 0.28 11.1 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF384) TPR_MLP1_2 PF07926.12 KPI45787.1 - 1.8 8.6 13.9 6.8 6.8 13.4 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1676 PF07898.13 KPI45787.1 - 2.1 8.4 6.2 3.6 7.6 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) A_deaminase PF00962.22 KPI45788.1 - 7.6e-41 140.5 0.0 9.1e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DnaJ PF00226.31 KPI45789.1 - 3.7e-11 43.0 0.3 2e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 DnaJ domain Ubiquitin_4 PF18036.1 KPI45789.1 - 0.12 12.4 0.0 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Cut12 PF11500.8 KPI45790.1 - 2.1 8.3 8.1 0.54 10.2 3.5 2.1 2 0 0 2 2 2 0 Spindle pole body formation-associated protein DNA_pol_phi PF04931.13 KPI45790.1 - 5 5.1 7.0 6.8 4.7 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Macoilin PF09726.9 KPI45791.1 - 0.57 8.7 11.3 0.79 8.2 11.3 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KPI45792.1 - 4.2e-27 95.0 24.9 1.3e-25 90.1 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLX9 PF15341.6 KPI45793.1 - 6.6e-34 117.1 0.6 1.1e-33 116.5 0.6 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HrpJ PF07201.11 KPI45793.1 - 0.021 15.2 0.7 0.18 12.1 0.2 2.0 2 0 0 2 2 2 0 HrpJ-like domain Fuseless PF15993.5 KPI45794.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Fuseless MFS_1 PF07690.16 KPI45795.1 - 6.4e-32 110.9 12.4 9.1e-32 110.3 12.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 KPI45795.1 - 0.044 13.8 0.8 0.17 11.9 0.8 2.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3671 PF12420.8 KPI45795.1 - 0.11 12.6 0.9 17 5.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function HIG_1_N PF04588.13 KPI45796.1 - 1.4e-22 79.6 1.0 2.4e-22 78.9 0.2 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region eIF2_C PF09173.11 KPI45797.1 - 1.9e-34 117.8 0.5 3.2e-34 117.0 0.5 1.4 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 KPI45797.1 - 1.7e-13 50.8 0.5 3.3e-13 49.8 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AnmK PF03702.14 KPI45798.1 - 2.7e-79 266.9 0.0 3.4e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase NTP_transf_9 PF04248.12 KPI45798.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF427) LepB_GAP_C PF18227.1 KPI45798.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain zf-C2H2 PF00096.26 KPI45800.1 - 4e-15 55.3 13.1 0.00097 19.5 0.0 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI45800.1 - 3.1e-11 43.1 13.3 0.1 13.5 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KPI45800.1 - 7.2e-10 38.9 5.0 0.14 12.5 0.5 4.6 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KPI45800.1 - 1.1e-07 31.5 5.0 0.37 10.6 0.0 4.3 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-met PF12874.7 KPI45800.1 - 1.4e-06 28.5 11.1 0.28 11.7 0.0 4.7 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KPI45800.1 - 4.4e-06 26.2 5.3 3 7.5 0.0 4.4 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KPI45800.1 - 0.00015 21.9 6.1 4.4 7.7 0.0 4.2 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding TRAF6_Z2 PF18048.1 KPI45800.1 - 0.00063 19.8 14.4 0.23 11.6 0.7 4.5 4 0 0 4 4 4 1 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 KPI45800.1 - 0.0011 19.3 9.1 0.95 9.8 0.2 4.2 3 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KPI45800.1 - 0.0014 18.5 7.5 3 7.9 0.1 4.2 4 0 0 4 4 4 2 Adenylate kinase, active site lid zf-FPG_IleRS PF06827.14 KPI45800.1 - 0.0061 16.4 10.5 0.11 12.4 0.2 4.1 4 0 0 4 4 4 1 Zinc finger found in FPG and IleRS zf-C2H2_9 PF16293.5 KPI45800.1 - 0.017 14.9 10.0 3.8 7.4 1.3 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-AD PF07776.15 KPI45800.1 - 0.034 14.4 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-C2H2_6 PF13912.6 KPI45800.1 - 0.035 14.1 10.8 1 9.4 1.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KPI45800.1 - 0.037 14.5 18.0 2.3 8.8 0.8 4.9 4 0 0 4 4 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KPI45800.1 - 0.043 13.9 14.9 1.1 9.4 4.6 3.0 2 2 0 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.11 KPI45800.1 - 0.045 13.3 4.7 17 5.1 0.1 3.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2HE PF16278.5 KPI45800.1 - 0.055 13.9 8.2 0.82 10.2 0.0 4.0 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KPI45800.1 - 0.081 12.8 17.5 0.35 10.8 0.2 3.9 4 0 0 4 4 3 0 zinc-finger of a C2HC-type Trm112p PF03966.16 KPI45800.1 - 0.14 12.8 8.2 1.2 9.7 0.5 3.5 2 2 0 2 2 2 0 Trm112p-like protein TFIIS_C PF01096.18 KPI45800.1 - 0.17 11.8 7.5 34 4.4 0.1 4.3 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) CxC7 PF18866.1 KPI45800.1 - 0.17 12.0 4.2 2.5 8.3 0.1 3.5 2 1 1 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases zf-ACC PF17848.1 KPI45800.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.5 4 0 0 4 4 3 0 Acetyl-coA carboxylase zinc finger domain zf-DNA_Pol PF08996.10 KPI45800.1 - 0.26 11.0 4.2 4.9 6.9 0.2 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DZR PF12773.7 KPI45800.1 - 0.39 10.8 15.5 0.32 11.1 1.3 3.2 2 1 1 3 3 3 0 Double zinc ribbon GcpE PF04551.14 KPI45800.1 - 0.46 9.5 2.1 3.1 6.8 0.1 2.3 2 1 0 2 2 2 0 GcpE protein zf-ISL3 PF14690.6 KPI45800.1 - 0.49 11.1 10.5 27 5.5 0.3 4.3 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-C2H2_12 PF18112.1 KPI45800.1 - 0.52 10.8 8.3 15 6.2 0.2 4.0 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Zn_Tnp_IS1595 PF12760.7 KPI45800.1 - 0.58 10.2 21.2 4.7 7.3 0.4 4.2 2 2 2 4 4 4 0 Transposase zinc-ribbon domain HypA PF01155.19 KPI45800.1 - 0.59 10.2 9.2 3.8 7.6 0.8 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 KPI45800.1 - 0.94 9.4 11.3 28 4.7 0.2 4.1 4 0 0 4 4 4 0 SprT-like zinc ribbon domain FYVE PF01363.21 KPI45800.1 - 1.1 9.4 13.8 0.15 12.2 1.6 2.6 2 1 0 2 2 2 0 FYVE zinc finger zf-3CxxC_2 PF17180.4 KPI45800.1 - 2.9 8.7 8.0 47 4.8 0.1 3.9 2 2 1 3 3 3 0 Zinc-binding domain Spt46 PF17734.1 KPI45800.1 - 3.9 7.2 8.1 0.61 9.9 0.6 2.7 2 1 2 4 4 4 0 Spermatogenesis-associated protein 46 zinc_ribbon_4 PF13717.6 KPI45800.1 - 4.5 7.3 15.1 22 5.1 0.4 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KPI45800.1 - 5.1 7.2 16.6 10 6.2 4.9 3.9 2 2 2 4 4 4 0 Transposase zinc-binding domain Rad50_zn_hook PF04423.14 KPI45800.1 - 6.7 6.6 16.8 0.34 10.8 0.4 4.1 3 1 1 4 4 4 0 Rad50 zinc hook motif TF_Zn_Ribbon PF08271.12 KPI45800.1 - 6.9 6.3 12.7 16 5.1 0.1 3.7 3 1 1 4 4 4 0 TFIIB zinc-binding zf-RING_4 PF14570.6 KPI45800.1 - 7 6.5 15.5 3.7 7.4 0.2 4.3 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain zf-Mss51 PF13824.6 KPI45800.1 - 8.4 6.6 15.8 0.94 9.6 2.7 3.0 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HET PF06985.11 KPI45802.1 - 5.9e-11 42.9 4.1 8.9e-11 42.3 4.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_tranf_2_3 PF13641.6 KPI45802.1 - 0.11 12.4 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF4407 PF14362.6 KPI45803.1 - 0.0012 18.2 33.7 0.089 12.1 0.2 4.0 2 1 0 3 3 3 3 Domain of unknown function (DUF4407) ATG16 PF08614.11 KPI45803.1 - 0.0046 17.2 0.8 0.0046 17.2 0.8 4.8 3 1 0 4 4 4 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KPI45803.1 - 0.075 13.5 42.6 0.8 10.1 0.3 4.1 3 1 1 4 4 4 0 Fez1 DUF5082 PF16888.5 KPI45803.1 - 0.12 12.7 21.7 0.056 13.7 9.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) DUF2935 PF11155.8 KPI45803.1 - 0.34 11.3 2.2 39 4.6 0.6 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Laminin_II PF06009.12 KPI45803.1 - 0.35 10.9 27.4 0.45 10.5 6.6 4.5 3 1 0 4 4 4 0 Laminin Domain II GAS PF13851.6 KPI45803.1 - 0.39 10.0 41.4 0.88 8.9 3.8 5.5 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KPI45803.1 - 0.43 10.6 17.0 0.13 12.4 2.9 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) T3SSipB PF16535.5 KPI45803.1 - 0.7 10.4 29.6 0.059 13.9 2.0 4.3 4 1 0 4 4 4 0 Type III cell invasion protein SipB Spc42p PF11544.8 KPI45803.1 - 0.8 9.7 15.3 28 4.8 0.2 5.6 5 1 1 6 6 6 0 Spindle pole body component Spc42p DUF2721 PF11026.8 KPI45803.1 - 1.1 9.2 4.0 0.6 10.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) BRE1 PF08647.11 KPI45803.1 - 2.7 8.1 38.9 1 9.4 1.4 5.6 3 1 1 5 5 5 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KPI45803.1 - 3 8.0 27.7 1.2 9.3 1.1 4.8 3 3 1 4 4 4 0 Fibrinogen alpha/beta chain family Dynein_C PF18199.1 KPI45803.1 - 3.1 6.9 9.0 0.8 8.9 4.5 2.0 1 1 1 2 2 2 0 Dynein heavy chain C-terminal domain PKcGMP_CC PF16808.5 KPI45803.1 - 7.6 6.5 19.2 5.5 6.9 0.1 5.6 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlaC_arch PF05377.11 KPI45803.1 - 7.8 7.0 14.2 9.4 6.7 0.5 5.5 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) Cation_efflux PF01545.21 KPI45804.1 - 1.8e-21 76.8 12.3 2.3e-21 76.4 12.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KPI45804.1 - 6.8e-05 22.9 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter adh_short PF00106.25 KPI45805.1 - 8.5e-46 155.9 0.0 1.1e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KPI45805.1 - 9.8e-32 110.4 0.0 1.2e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KPI45805.1 - 1.9e-08 34.5 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KPI45805.1 - 5.5e-06 26.4 0.0 9e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KPI45805.1 - 6.2e-05 22.6 0.0 9.7e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KPI45805.1 - 0.0012 18.1 0.0 0.0023 17.1 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 KPI45805.1 - 0.025 14.1 0.2 0.06 12.9 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family zf-RING_2 PF13639.6 KPI45806.1 - 1.3e-10 41.4 8.0 1.9e-10 40.9 8.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KPI45806.1 - 2.9e-07 30.4 2.6 4.7e-07 29.7 2.6 1.3 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KPI45806.1 - 1.9e-06 28.0 5.4 3.5e-06 27.1 5.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KPI45806.1 - 5.1e-06 26.7 11.2 2.1e-05 24.7 11.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KPI45806.1 - 8.2e-06 25.8 6.0 2.7e-05 24.1 6.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KPI45806.1 - 1e-05 25.1 3.7 2e-05 24.2 3.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KPI45806.1 - 1.2e-05 25.1 5.3 1.8e-05 24.5 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KPI45806.1 - 5.4e-05 23.0 7.2 0.00013 21.7 7.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI45806.1 - 0.0016 18.3 5.2 0.0028 17.6 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KPI45806.1 - 0.019 14.7 7.1 0.03 14.1 7.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KPI45806.1 - 0.022 14.7 5.2 0.023 14.6 2.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KPI45806.1 - 0.079 12.8 7.0 0.15 12.0 7.0 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KPI45806.1 - 0.12 12.3 1.9 0.24 11.3 1.9 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KPI45806.1 - 0.22 11.7 6.6 0.089 13.0 1.6 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KPI45806.1 - 0.33 10.9 5.9 18 5.3 5.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KPI45806.1 - 0.34 11.1 8.1 0.6 10.3 8.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.12 KPI45806.1 - 0.38 11.1 3.4 9.9 6.6 0.1 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 KPI45806.1 - 0.74 9.8 7.8 1.2 9.1 7.8 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KPI45806.1 - 1.2 8.8 9.7 0.8 9.4 6.9 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type DUF5497 PF17601.2 KPI45807.1 - 0.092 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5497) NRBF2 PF08961.10 KPI45807.1 - 0.22 11.1 6.4 0.4 10.3 0.7 3.0 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 KPI45807.1 - 0.64 10.5 12.4 0.49 10.9 1.2 2.9 2 0 0 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 KPI45807.1 - 3.3 7.9 8.2 2 8.7 0.4 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KPI45807.1 - 5.3 7.1 10.8 13 5.8 2.6 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 KPI45807.1 - 9.3 6.2 6.5 0.96 9.4 1.2 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PIG-U PF06728.13 KPI45808.1 - 1.1e-109 367.1 24.1 1.2e-109 366.9 24.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KPI45808.1 - 0.012 15.3 7.4 0.019 14.7 7.4 1.3 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Striatin PF08232.12 KPI45808.1 - 0.25 11.9 0.0 0.34 11.5 0.0 1.1 1 0 0 1 1 1 0 Striatin family MFS_1 PF07690.16 KPI45810.1 - 5.3e-06 25.6 22.7 2.9e-05 23.2 22.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5559 PF17714.1 KPI45810.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) MgtE PF01769.16 KPI45810.1 - 4.7 7.6 14.5 1.6 9.1 0.1 2.7 1 1 2 3 3 3 0 Divalent cation transporter zf-H2C2_2 PF13465.6 KPI45812.1 - 3e-11 43.2 18.3 2.8e-05 24.3 2.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KPI45812.1 - 9.7e-09 35.2 24.0 0.016 15.7 7.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI45812.1 - 6.9e-06 26.5 21.2 0.083 13.8 5.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KPI45812.1 - 0.00044 20.0 2.0 0.13 12.1 0.5 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-Di19 PF05605.12 KPI45812.1 - 0.0013 18.9 10.6 0.0038 17.5 6.9 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KPI45812.1 - 0.0024 17.8 19.1 0.028 14.4 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KPI45812.1 - 0.0074 16.4 5.1 0.027 14.6 1.6 2.5 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_9 PF16293.5 KPI45812.1 - 0.0087 15.9 2.8 3.2 7.7 0.2 3.3 1 1 2 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KPI45812.1 - 0.013 15.3 0.9 0.013 15.3 0.9 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 KPI45812.1 - 0.077 13.3 2.5 31 4.9 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon PKcGMP_CC PF16808.5 KPI45812.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Prok-RING_1 PF14446.6 KPI45812.1 - 0.19 11.7 2.4 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 GAGA PF09237.11 KPI45812.1 - 0.23 11.3 4.7 1.9 8.3 0.5 2.7 1 1 1 2 2 2 0 GAGA factor DZR PF12773.7 KPI45812.1 - 0.37 10.8 7.8 3.4 7.8 7.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 KPI45812.1 - 0.51 10.4 10.1 3.5 7.7 5.0 2.7 1 1 1 2 2 2 0 BED zinc finger Zn_ribbon_SprT PF17283.2 KPI45812.1 - 0.69 9.9 13.4 1.1 9.2 5.5 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KPI45812.1 - 0.73 9.9 5.4 2.7 8.0 5.3 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-C2HE PF16278.5 KPI45812.1 - 0.8 10.2 16.7 0.26 11.8 0.9 2.8 2 1 1 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 KPI45812.1 - 1 9.4 3.6 3.2 7.8 3.6 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KPI45812.1 - 1.4 8.5 5.0 4.5 6.9 0.7 2.7 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 KPI45812.1 - 1.5 9.7 5.6 0.66 10.8 1.0 2.0 1 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 KPI45812.1 - 3.4 7.5 5.2 6.7 6.6 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.9 KPI45812.1 - 4.2 7.6 5.1 16 5.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 KPI45812.1 - 4.2 7.8 11.7 3.7 7.9 1.8 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PhnA_Zn_Ribbon PF08274.12 KPI45812.1 - 4.3 7.4 5.9 37 4.4 3.0 2.7 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-C2H2_jaz PF12171.8 KPI45812.1 - 4.6 7.7 11.7 2.7 8.4 3.8 3.2 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KPI45812.1 - 5.9 6.6 9.4 4.8 6.9 0.5 3.3 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-CHCC PF10276.9 KPI45812.1 - 7.9 6.6 6.5 3.7 7.7 0.2 2.6 3 0 0 3 3 2 0 Zinc-finger domain Peptidase_M28 PF04389.17 KPI45814.1 - 3.2e-29 102.0 0.0 5.3e-29 101.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 Na_Ca_ex PF01699.24 KPI45815.1 - 1.4e-51 174.4 43.4 3.9e-26 91.8 21.1 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Fcf1 PF04900.12 KPI45816.1 - 2.7e-37 127.1 0.1 5.3e-37 126.2 0.1 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KPI45816.1 - 1e-11 45.2 0.1 3.6e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 PIN like domain DUF4706 PF15797.5 KPI45816.1 - 0.025 15.1 0.1 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) WD40 PF00400.32 KPI45817.1 - 8.3e-28 96.1 4.1 3.7e-05 24.4 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI45817.1 - 4e-12 46.3 0.0 0.006 16.9 0.0 4.8 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI45817.1 - 0.0067 15.4 0.1 4.4 6.2 0.0 2.8 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein 2_5_RNA_ligase2 PF13563.6 KPI45819.1 - 0.00028 20.8 0.3 0.00038 20.4 0.3 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MMR_HSR1 PF01926.23 KPI45820.1 - 7.9e-09 35.6 0.0 7.9e-09 35.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KPI45820.1 - 0.0062 15.9 0.0 0.0062 15.9 0.0 2.5 2 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KPI45820.1 - 0.014 15.3 0.1 0.014 15.3 0.1 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 KPI45820.1 - 0.018 15.6 9.6 0.019 15.5 0.0 3.4 1 1 3 4 4 4 0 AAA domain AAA_22 PF13401.6 KPI45820.1 - 0.034 14.4 0.0 0.034 14.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KPI45820.1 - 0.037 14.1 0.3 0.037 14.1 0.3 3.3 2 1 1 3 3 3 0 Helicase HerA, central domain FeoB_N PF02421.18 KPI45820.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.6 3 1 0 3 3 3 0 Ferrous iron transport protein B DUF572 PF04502.13 KPI45820.1 - 0.15 11.7 25.7 0.23 11.1 25.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2721 PF11026.8 KPI45820.1 - 0.44 10.5 0.1 0.44 10.5 0.1 2.7 3 1 0 3 3 2 0 Protein of unknown function (DUF2721) ABC_tran PF00005.27 KPI45820.1 - 0.53 10.8 0.0 0.53 10.8 0.0 3.2 2 1 0 2 2 2 0 ABC transporter DUF3584 PF12128.8 KPI45820.1 - 2.5 5.5 39.0 4.2 4.8 39.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fungal_trans PF04082.18 KPI45821.1 - 6e-27 94.3 0.0 9.9e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSP20 PF00011.21 KPI45822.1 - 8.6e-17 61.2 2.1 3.1e-11 43.3 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KPI45822.1 - 0.076 12.6 0.0 7.2 6.3 0.0 2.2 2 0 0 2 2 2 0 HSP20-like domain found in ArsA DUF4662 PF15578.6 KPI45822.1 - 0.33 10.7 4.3 0.46 10.2 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) ADH_zinc_N PF00107.26 KPI45823.1 - 1.4e-14 54.2 0.0 2.7e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KPI45823.1 - 9.4e-09 35.1 0.6 0.00095 18.7 0.0 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KPI45823.1 - 0.021 15.9 0.0 0.033 15.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PIG-S PF10510.9 KPI45824.1 - 5.5e-125 418.1 0.0 6.7e-125 417.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein 3H PF02829.14 KPI45824.1 - 0.12 12.7 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 3H domain Kinesin PF00225.23 KPI45827.1 - 9.7e-110 366.6 1.1 9.7e-110 366.6 1.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KPI45827.1 - 2.3e-24 86.0 1.7 7.4e-24 84.4 0.0 2.8 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 KPI45827.1 - 1.1e-06 29.1 2.0 1.1e-06 29.1 2.0 5.8 4 2 3 7 7 7 1 Kinesin-associated microtubule-binding CZB PF13682.6 KPI45827.1 - 0.34 11.4 1.7 2.6 8.5 0.0 3.3 5 0 0 5 5 5 0 Chemoreceptor zinc-binding domain Baculo_PEP_C PF04513.12 KPI45827.1 - 0.43 10.6 0.0 0.43 10.6 0.0 6.2 3 1 5 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus CMD PF02627.20 KPI45828.1 - 9.3e-05 22.4 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family His_Phos_1 PF00300.22 KPI45829.1 - 1.9e-14 53.8 0.0 8.2e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Flavoprotein PF02441.19 KPI45830.1 - 2.5e-06 27.3 0.0 5.3e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Flavoprotein Dimer_Tnp_hAT PF05699.14 KPI45830.1 - 4.2 7.2 10.2 0.66 9.8 0.1 4.0 4 1 1 5 5 5 0 hAT family C-terminal dimerisation region FAD_binding_3 PF01494.19 KPI45831.1 - 2.8e-13 49.9 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KPI45831.1 - 2.4e-06 27.7 0.2 5.6e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KPI45831.1 - 2.6e-05 23.6 5.2 0.0058 15.9 0.5 2.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KPI45831.1 - 3.4e-05 23.6 0.8 0.0012 18.5 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KPI45831.1 - 0.0028 16.6 2.8 0.78 8.5 0.7 2.5 2 1 1 3 3 3 2 Tryptophan halogenase GIDA PF01134.22 KPI45831.1 - 0.0053 15.9 1.1 0.013 14.6 1.1 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KPI45831.1 - 0.013 14.6 0.1 0.036 13.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KPI45831.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KPI45831.1 - 0.017 13.8 0.8 0.031 13.0 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein Rossmann-like PF10727.9 KPI45831.1 - 0.02 14.7 0.6 0.037 13.9 0.1 1.6 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 KPI45831.1 - 0.025 14.5 0.3 0.04 13.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KPI45831.1 - 0.028 15.0 0.2 0.066 13.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KPI45831.1 - 0.034 13.4 1.3 0.18 11.0 0.9 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KPI45831.1 - 0.12 12.4 1.4 4.8 7.1 0.2 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KPI45831.1 - 0.35 9.9 1.1 2.3 7.2 1.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Ran-binding PF05508.11 KPI45833.1 - 3.1e-122 407.5 1.1 3.8e-122 407.2 1.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein DUF3526 PF12040.8 KPI45833.1 - 0.13 12.7 0.4 0.32 11.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Acetyltransf_2 PF00797.17 KPI45834.1 - 6.3e-40 137.5 0.0 7.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Peptidase_C71 PF12386.8 KPI45834.1 - 0.0081 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Pseudomurein endo-isopeptidase Pei Scytalone_dh PF02982.14 KPI45834.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Syja_N PF02383.18 KPI45836.1 - 4.6e-88 295.6 0.0 5.9e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.15 KPI45836.1 - 0.13 12.7 0.0 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 FUN14 family Acetyltransf_3 PF13302.7 KPI45837.1 - 8.7e-25 88.0 0.0 1.2e-24 87.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KPI45837.1 - 1.2e-06 28.2 0.2 0.051 13.3 0.1 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI45837.1 - 0.00057 19.8 0.1 0.037 14.0 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KPI45837.1 - 0.0011 19.2 0.1 0.055 13.7 0.2 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI45837.1 - 0.019 15.4 0.5 0.035 14.5 0.5 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease PF00324.21 KPI45838.1 - 2.5e-96 323.2 44.2 2.9e-96 323.0 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KPI45838.1 - 2.4e-22 79.4 45.9 3.3e-22 78.9 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease TraS PF10624.9 KPI45838.1 - 0.086 12.8 0.2 0.086 12.8 0.2 1.8 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Proteasome PF00227.26 KPI45840.1 - 2.3e-33 115.3 0.0 2.7e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 KPI45842.1 - 7.7e-38 130.4 0.0 2.4e-37 128.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45842.1 - 5.6e-27 94.7 0.0 8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KPI45842.1 - 0.0084 16.1 0.4 0.035 14.0 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KPI45842.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KPI45842.1 - 0.19 11.1 0.1 0.45 9.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family E7R PF17467.2 KPI45843.1 - 0.0035 17.4 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Viral Protein E7 Ric8 PF10165.9 KPI45845.1 - 5.1e-98 329.1 0.0 6e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn ATP-synt_S1 PF05827.12 KPI45846.1 - 6e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PIN_6 PF17146.4 KPI45846.1 - 0.026 15.0 0.0 6.3 7.4 0.0 2.5 2 0 0 2 2 2 0 PIN domain of ribonuclease DUF5632 PF18646.1 KPI45846.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5632) Cytochrom_C1 PF02167.15 KPI45849.1 - 2.2e-91 305.5 0.0 2.7e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.21 KPI45849.1 - 0.016 16.4 1.0 0.11 13.6 0.1 2.7 3 1 0 3 3 3 0 Cytochrome c Cytochrome_CBB3 PF13442.6 KPI45849.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III HCNGP PF07818.13 KPI45850.1 - 1.9e-26 92.6 0.0 3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Fungal_trans_2 PF11951.8 KPI45851.1 - 2.2e-05 23.5 0.0 2.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpeto_peptide PF14409.6 KPI45851.1 - 0.048 13.9 0.4 5.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Herpetosiphon RRM_1 PF00076.22 KPI45852.1 - 5e-08 32.7 0.0 1.2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L23 PF00276.20 KPI45852.1 - 0.014 15.7 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L23 Methyltransf_PK PF05891.12 KPI45853.1 - 6.6e-63 212.2 0.0 5.3e-49 166.7 0.0 2.0 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KPI45853.1 - 1.4e-05 25.0 0.0 3.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KPI45853.1 - 0.0012 19.6 0.0 0.0025 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DUF1754 PF08555.10 KPI45853.1 - 0.086 13.6 0.2 0.13 13.1 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Nucleo_P87 PF07267.11 KPI45853.1 - 0.17 10.7 0.1 0.2 10.5 0.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyoxalase PF00903.25 KPI45854.1 - 0.00037 20.7 0.0 0.00062 20.0 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KPI45854.1 - 0.033 14.3 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Glyco_hydro_61 PF03443.14 KPI45856.1 - 9.5e-49 166.1 0.3 1.4e-48 165.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KPI45856.1 - 1.1e-13 50.8 13.0 2.7e-13 49.6 13.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Ribosomal_L14 PF00238.19 KPI45857.1 - 9.5e-35 119.3 2.2 1e-34 119.2 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Polysacc_synt_4 PF04669.13 KPI45858.1 - 1.5e-18 67.0 0.2 3.1e-16 59.5 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis p450 PF00067.22 KPI45859.1 - 2.4e-77 260.7 0.0 3.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ilm1 PF10311.9 KPI45860.1 - 1.6e-22 79.9 0.0 2e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 PQ-loop PF04193.14 KPI45861.1 - 5.3e-25 87.0 4.6 4.8e-15 55.1 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat ATP13 PF12921.7 KPI45862.1 - 0.21 11.5 0.6 21 5.0 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ATPase expression MFS_1 PF07690.16 KPI45864.1 - 2.7e-30 105.5 36.6 2.7e-30 105.5 36.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI45864.1 - 1.6e-06 27.3 33.4 1.8e-05 23.8 33.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4481 PF14800.6 KPI45864.1 - 0.7 9.3 3.8 0.25 10.8 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4481) Amidase PF01425.21 KPI45865.1 - 8.7e-54 183.2 0.3 1.4e-46 159.4 0.5 2.3 2 1 0 2 2 2 2 Amidase DUF3506 PF12014.8 KPI45867.1 - 1.5e-48 164.4 0.0 2.8e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) PHD PF00628.29 KPI45868.1 - 8.9e-17 60.7 16.2 1.3e-10 41.0 9.2 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KPI45868.1 - 0.0013 18.4 6.0 0.021 14.4 2.3 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KPI45868.1 - 0.0018 17.8 3.1 0.0018 17.8 3.1 2.8 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 KPI45868.1 - 0.041 13.8 9.7 1.3 8.9 3.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KPI45868.1 - 0.28 11.3 14.7 2.4 8.3 0.2 2.6 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 KPI45868.1 - 2.3 8.4 12.0 2.2 8.4 0.2 2.8 2 1 0 2 2 2 0 KIAA1045 RING finger PAP2 PF01569.21 KPI45869.1 - 3.3e-23 82.0 5.9 3.9e-23 81.7 3.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily DUF1453 PF07301.11 KPI45869.1 - 0.064 13.3 0.5 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) MAT1 PF06391.13 KPI45870.1 - 6.6e-26 91.4 7.3 8.7e-26 91.0 7.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KPI45870.1 - 4.2e-16 58.6 8.3 6.8e-16 57.9 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KPI45870.1 - 2.7e-05 23.9 7.1 5e-05 23.1 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI45870.1 - 0.00023 21.1 7.1 0.00044 20.2 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KPI45870.1 - 0.00064 19.5 6.0 0.0013 18.5 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KPI45870.1 - 0.0011 19.3 7.8 0.0018 18.6 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KPI45870.1 - 0.013 15.5 9.6 0.025 14.5 4.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 KPI45870.1 - 0.049 13.8 0.9 0.12 12.5 0.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KPI45870.1 - 0.11 12.6 5.6 0.32 11.2 5.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KPI45870.1 - 0.16 11.8 4.9 0.41 10.5 4.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 KPI45870.1 - 0.43 10.2 5.1 0.83 9.3 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KPI45870.1 - 2 8.3 10.0 0.52 10.2 3.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 KPI45870.1 - 3.2 7.7 8.1 0.48 10.3 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) HlyIII PF03006.20 KPI45871.1 - 1.3e-58 198.3 14.0 1.7e-58 198.0 14.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ribophorin_II PF05817.14 KPI45872.1 - 3.4e-26 92.0 0.0 4.4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II F-box-like PF12937.7 KPI45874.1 - 0.0009 19.1 1.2 0.002 18.0 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KPI45874.1 - 0.05 13.5 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 F-box domain GHMP_kinases_N PF00288.26 KPI45875.1 - 1.3e-16 60.6 0.0 3.1e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KPI45875.1 - 2e-07 31.3 0.0 4.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KPI45875.1 - 0.00023 20.7 0.1 0.00058 19.4 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Abhydrolase_1 PF00561.20 KPI45876.1 - 3.4e-05 23.6 0.2 4.8e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold RRN9 PF10680.9 KPI45877.1 - 1e-16 60.9 1.6 4.4e-16 58.9 1.6 2.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Zip PF02535.22 KPI45878.1 - 4.1e-67 226.8 3.1 4.7e-67 226.6 3.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter SAP PF02037.27 KPI45879.1 - 5.7e-13 48.3 0.2 1.1e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KPI45879.1 - 1.8e-06 27.7 2.3 2.6e-06 27.1 0.1 2.3 2 1 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KPI45879.1 - 0.019 14.7 0.2 0.044 13.5 0.2 1.7 1 1 0 1 1 1 0 HeH/LEM domain FANC_SAP PF18081.1 KPI45879.1 - 0.049 13.8 0.7 0.17 12.1 0.7 1.9 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain DUF1179 PF06678.11 KPI45879.1 - 1.6 8.7 6.9 4.6 7.3 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) ADH_zinc_N PF00107.26 KPI45880.1 - 9.1e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI45880.1 - 0.00018 21.3 0.0 0.00047 20.0 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Na_H_antiport_3 PF07399.11 KPI45881.1 - 0.025 13.5 0.5 0.032 13.1 0.5 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter SGL PF08450.12 KPI45882.1 - 1.5e-49 168.8 0.3 2.3e-49 168.2 0.3 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KPI45882.1 - 0.0027 17.9 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 KPI45882.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Strictosidine synthase Amidase PF01425.21 KPI45883.1 - 3.6e-50 171.3 1.9 2.1e-47 162.1 1.9 2.9 1 1 0 1 1 1 1 Amidase CBM_35 PF16990.5 KPI45883.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) Gpr1_Fun34_YaaH PF01184.19 KPI45886.1 - 2.9e-87 291.6 20.9 3.5e-87 291.4 20.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Spherulin4 PF12138.8 KPI45888.1 - 1.1e-57 195.5 0.0 1.3e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 ADH_zinc_N_2 PF13602.6 KPI45889.1 - 6.2e-14 53.2 0.0 1.2e-13 52.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KPI45889.1 - 2.3e-05 24.4 0.1 6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI45889.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Kelch_1 PF01344.25 KPI45889.1 - 0.071 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Kelch motif PALP PF00291.25 KPI45890.1 - 2.6e-57 194.5 2.9 3.3e-57 194.2 2.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme hDGE_amylase PF14701.6 KPI45891.1 - 2.8e-173 577.1 0.0 4.2e-173 576.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KPI45891.1 - 1.3e-122 409.5 0.0 2.1e-122 408.8 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KPI45891.1 - 1.9e-84 283.3 0.0 3.9e-84 282.3 0.0 1.6 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KPI45891.1 - 5.4e-32 109.8 0.0 1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KPI45891.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Cornifin PF02389.15 KPI45892.1 - 2.3 8.4 8.5 0.6 10.3 0.5 2.8 2 1 0 2 2 2 0 Cornifin (SPRR) family 4HBT_3 PF13622.6 KPI45893.1 - 4.7e-44 151.5 0.0 5.5e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Cyclin PF08613.11 KPI45894.1 - 4.9e-34 118.0 5.0 3.7e-13 50.2 0.1 3.6 3 0 0 3 3 3 3 Cyclin DUF934 PF06073.12 KPI45895.1 - 0.071 13.0 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) AMH_N PF04709.12 KPI45895.1 - 0.16 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region adh_short_C2 PF13561.6 KPI45897.1 - 2.9e-33 115.4 2.1 5.6e-25 88.3 0.0 3.0 1 1 2 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KPI45897.1 - 5.7e-31 107.5 2.7 1.4e-24 86.6 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KPI45897.1 - 8.1e-06 25.9 1.7 0.0049 16.8 0.0 2.1 1 1 1 2 2 2 2 KR domain CorA PF01544.18 KPI45898.1 - 0.0031 16.9 3.1 0.008 15.5 3.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4972 PF16342.5 KPI45898.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4972) Virul_fac_BrkB PF03631.15 KPI45898.1 - 0.059 13.0 0.6 0.11 12.1 0.4 1.4 2 0 0 2 2 2 0 Virulence factor BrkB Methyltransf_16 PF10294.9 KPI45899.1 - 2.1e-38 131.8 0.1 4.2e-38 130.8 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KPI45899.1 - 5.1e-06 27.1 0.0 1.4e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KPI45899.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KPI45899.1 - 3.7e-05 23.3 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KPI45899.1 - 0.00012 22.7 0.1 0.00043 21.0 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI45899.1 - 0.0034 17.2 0.1 0.0064 16.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KPI45899.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Pkinase PF00069.25 KPI45900.1 - 4.3e-36 124.6 0.0 5.4e-25 88.2 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 KPI45900.1 - 2.2e-25 89.3 0.1 1.9e-18 66.9 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KPI45900.1 - 2.7e-19 69.5 0.0 6.4e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glycoprotein PF03409.15 KPI45900.1 - 0.097 11.5 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane glycoprotein PQQ PF01011.21 KPI45900.1 - 0.17 11.9 0.1 44 4.2 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Telomerase_RBD PF12009.8 KPI45901.1 - 7.4e-41 139.4 0.1 1.6e-40 138.3 0.1 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KPI45901.1 - 0.088 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Codanin-1_C PF15296.6 KPI45901.1 - 0.18 11.9 1.6 0.79 9.8 1.3 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus MFS_1 PF07690.16 KPI45902.1 - 2.2e-33 115.6 14.1 2.2e-33 115.6 14.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily CYYR1 PF10873.8 KPI45903.1 - 0.032 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Herpes_gE PF02480.16 KPI45903.1 - 0.081 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Acyl-CoA_dh_1 PF00441.24 KPI45904.1 - 2.7e-32 112.1 2.7 2.7e-32 112.1 1.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KPI45904.1 - 1.1e-19 70.4 0.0 2.5e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KPI45904.1 - 5.3e-18 65.0 0.5 1e-17 64.1 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KPI45904.1 - 2.4e-09 37.8 0.1 8.9e-09 36.0 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KPI45904.1 - 5.6e-05 23.4 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cytokin_check_N PF10407.9 KPI45905.1 - 1.4e-08 34.6 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Par3_HAL_N_term PF12053.8 KPI45905.1 - 0.088 13.0 0.1 0.088 13.0 0.1 2.5 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins AAA PF00004.29 KPI45906.1 - 2.8e-14 53.7 0.0 9.5e-14 52.0 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KPI45906.1 - 6.3e-11 43.0 0.5 3.4e-10 40.6 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI45906.1 - 1e-09 38.8 0.0 2.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KPI45906.1 - 0.00036 20.5 0.1 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_7 PF12775.7 KPI45906.1 - 0.00059 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KPI45906.1 - 0.0023 17.9 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KPI45906.1 - 0.0028 17.1 0.0 0.0075 15.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 KPI45906.1 - 0.0045 17.3 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KPI45906.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KPI45906.1 - 0.011 15.9 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KPI45906.1 - 0.016 15.1 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KPI45906.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 KPI45906.1 - 0.023 13.9 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KPI45906.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KPI45906.1 - 0.026 14.3 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KPI45906.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KPI45906.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KPI45906.1 - 0.048 12.9 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 KPI45906.1 - 0.062 13.2 0.1 0.4 10.6 0.1 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain PIF1 PF05970.14 KPI45906.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Mg_chelatase PF01078.21 KPI45906.1 - 0.071 12.5 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_lid_10 PF17872.1 KPI45906.1 - 0.099 12.8 0.5 0.43 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA lid domain IstB_IS21 PF01695.17 KPI45906.1 - 0.11 12.3 0.0 0.6 9.8 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein PBP PF01161.20 KPI45907.1 - 8.7e-15 55.2 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Mucin PF01456.17 KPI45907.1 - 0.0067 16.4 12.9 0.0067 16.4 12.9 1.8 2 1 0 2 2 2 1 Mucin-like glycoprotein DUF1929 PF09118.11 KPI45907.1 - 0.033 14.5 0.0 0.11 12.8 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1929) TauD PF02668.16 KPI45909.1 - 1.5e-53 182.3 3.1 4.5e-44 151.3 0.8 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family LRR_4 PF12799.7 KPI45910.1 - 9.6e-10 38.6 3.3 0.018 15.4 0.1 6.9 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KPI45910.1 - 2.2e-05 24.1 2.1 0.05 13.4 0.1 5.3 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.6 KPI45910.1 - 0.015 15.3 13.3 1 9.6 0.0 5.7 7 0 0 7 7 7 0 Leucine Rich repeat Tmemb_9 PF05434.11 KPI45910.1 - 2.7 7.9 5.9 5.8 6.8 5.9 1.5 1 0 0 1 1 1 0 TMEM9 LRR_1 PF00560.33 KPI45910.1 - 3.5 8.5 8.3 19 6.3 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat DUF4604 PF15377.6 KPI45910.1 - 5.7 7.3 21.0 1.7 9.0 18.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF3510 PF12022.8 KPI45910.1 - 6 7.3 13.7 2.4 8.6 5.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Mo-co_dimer PF03404.16 KPI45911.1 - 1.7e-57 193.3 0.1 3.3e-57 192.4 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KPI45911.1 - 1.2e-53 181.3 0.0 2.3e-53 180.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KPI45911.1 - 4.3e-33 113.6 0.0 7.6e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KPI45911.1 - 2.9e-28 98.7 0.0 5.5e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KPI45911.1 - 3.3e-20 72.0 0.0 7.2e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KPI45911.1 - 0.00069 19.8 0.1 0.19 11.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain PH_10 PF15411.6 KPI45912.1 - 1.6e-25 89.7 0.2 3.4e-25 88.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KPI45912.1 - 4.9e-15 56.2 0.0 8.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KPI45912.1 - 4.8e-10 39.6 0.2 1.8e-09 37.7 0.1 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 KPI45912.1 - 0.0002 21.2 4.0 0.00036 20.4 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KPI45912.1 - 0.00058 20.1 3.4 0.0011 19.3 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KPI45912.1 - 0.005 16.7 3.7 0.0092 15.8 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KPI45912.1 - 0.0064 16.1 3.4 0.012 15.2 3.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KPI45912.1 - 0.023 15.0 1.7 0.052 13.9 1.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KPI45912.1 - 0.025 14.4 3.5 0.049 13.5 3.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KPI45912.1 - 0.061 13.2 1.5 0.11 12.4 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KPI45912.1 - 0.084 13.2 4.4 0.15 12.4 4.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.6 KPI45912.1 - 0.14 12.3 1.0 0.32 11.0 1.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KPI45912.1 - 1.1 9.4 4.8 2.2 8.5 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KPI45912.1 - 1.3 9.0 4.0 2.4 8.1 4.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KPI45912.1 - 4.6 7.4 5.8 21 5.3 5.8 2.0 1 1 0 1 1 1 0 Zinc-finger SKG6 PF08693.10 KPI45913.1 - 0.0008 18.8 0.6 0.0016 17.8 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain WD40 PF00400.32 KPI45915.1 - 1.4e-11 44.7 12.4 1.8e-05 25.4 0.4 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat MFS_1 PF07690.16 KPI45916.1 - 1.3e-16 60.5 31.8 1.5e-14 53.7 31.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily T3SS_needle_F PF09392.10 KPI45917.1 - 0.052 13.7 0.9 2.4 8.4 1.9 2.9 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF SesA PF17107.5 KPI45917.1 - 0.51 10.5 5.6 1.1 9.4 0.0 3.5 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CHAT PF12770.7 KPI45919.1 - 4.8e-29 101.7 0.1 1.1e-28 100.5 0.1 1.6 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 KPI45919.1 - 0.0021 17.3 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 Ribosomal_L38e PF01781.18 KPI45920.1 - 5.7e-28 96.8 6.6 9.6e-28 96.1 6.6 1.4 1 1 0 1 1 1 1 Ribosomal L38e protein family GDP_Man_Dehyd PF16363.5 KPI45921.1 - 1.4e-36 126.5 0.0 1.3e-35 123.4 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KPI45921.1 - 1.9e-36 125.8 0.0 2.2e-35 122.2 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KPI45921.1 - 1.1e-08 34.5 0.0 8.4e-08 31.7 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KPI45921.1 - 1.5e-06 27.5 0.1 4.8e-05 22.5 0.1 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KPI45921.1 - 4.8e-06 25.9 0.0 4.2e-05 22.8 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KPI45921.1 - 0.00042 20.3 0.0 0.00086 19.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KPI45921.1 - 0.0052 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KPI45923.1 - 1.8e-13 50.6 0.0 3.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KPI45923.1 - 4.5e-08 33.0 0.0 1.5e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KPI45923.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KPI45923.1 - 0.028 15.5 0.1 1.5 9.9 0.0 2.7 2 1 1 3 3 3 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KPI45923.1 - 0.047 13.0 0.1 0.084 12.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cnd2 PF05786.14 KPI45924.1 - 1.6e-240 800.9 3.9 2.1e-240 800.5 3.9 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KPI45924.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAM176 PF14851.6 KPI45924.1 - 2.8 7.6 6.3 7.2 6.3 3.2 2.8 2 0 0 2 2 2 0 FAM176 family S-antigen PF05756.11 KPI45924.1 - 3.2 8.2 7.2 0.44 11.0 2.5 2.0 2 0 0 2 2 2 0 S-antigen protein 4HBT PF03061.22 KPI45925.1 - 2.8e-08 34.0 0.0 4.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Cornichon PF03311.14 KPI45926.1 - 7.1e-50 168.4 13.7 8.1e-50 168.2 13.7 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1769 PF08588.10 KPI45927.1 - 3.8e-30 103.9 0.4 9e-30 102.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) AveC_like PF17198.4 KPI45928.1 - 0.0053 16.2 0.1 0.0078 15.7 0.1 1.3 1 0 0 1 1 1 1 Spirocyclase AveC-like Gate PF07670.14 KPI45928.1 - 0.049 13.9 1.8 0.35 11.2 1.2 2.0 1 1 1 2 2 2 0 Nucleoside recognition DUF4044 PF13253.6 KPI45928.1 - 0.75 9.4 5.2 1.5 8.4 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) GST_N_3 PF13417.6 KPI45929.1 - 2.9e-12 46.8 0.0 7e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KPI45929.1 - 1.8e-09 37.7 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KPI45929.1 - 1.6e-08 34.7 0.0 4.2e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KPI45929.1 - 1e-07 32.2 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KPI45929.1 - 2.6e-06 27.4 0.1 1e-05 25.5 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KPI45929.1 - 0.00013 22.7 0.1 0.18 12.5 0.0 2.8 1 1 1 2 2 2 2 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KPI45929.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KPI45930.1 - 4.5e-33 114.6 29.4 4.5e-33 114.6 29.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KPI45930.1 - 4e-11 42.4 12.0 4e-11 42.4 12.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter bZIP_1 PF00170.21 KPI45931.1 - 2.5e-10 40.3 12.8 2.5e-10 40.3 12.8 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KPI45931.1 - 0.001 19.5 4.8 0.0026 18.2 4.8 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KPI45931.1 - 0.0014 18.7 10.2 0.0014 18.7 10.2 2.6 3 1 0 3 3 3 1 Basic region leucine zipper Pkinase PF00069.25 KPI45932.1 - 5.2e-16 58.8 0.1 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KPI45932.1 - 2.1e-07 30.5 0.0 2.2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DAO PF01266.24 KPI45933.1 - 1.1e-34 120.6 0.1 1.3e-34 120.3 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KPI45933.1 - 0.00026 20.4 0.0 0.0075 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI45933.1 - 0.0026 17.9 0.0 0.0072 16.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KPI45933.1 - 0.0044 17.0 0.1 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Tho2 PF11262.8 KPI45933.1 - 0.038 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pyr_redox_2 PF07992.14 KPI45933.1 - 0.11 11.8 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tropomyosin_1 PF12718.7 KPI45934.1 - 1.4e-47 161.4 39.0 1.9e-47 161.0 39.0 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KPI45934.1 - 4.8e-08 32.7 34.7 1.3e-05 24.7 12.2 3.0 1 1 2 3 3 3 2 Tropomyosin Cep57_CLD_2 PF14197.6 KPI45934.1 - 6.1e-05 23.0 33.4 0.00098 19.2 10.3 4.0 1 1 2 3 3 3 2 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 KPI45934.1 - 0.00035 20.6 33.9 0.1 12.7 1.4 4.5 2 1 4 6 6 6 4 bZIP transcription factor DUF4200 PF13863.6 KPI45934.1 - 0.0005 20.5 33.9 0.075 13.4 14.8 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) KLRAQ PF10205.9 KPI45934.1 - 0.00063 19.9 12.6 0.00063 19.9 12.6 3.1 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein ADIP PF11559.8 KPI45934.1 - 0.0017 18.5 34.8 0.0031 17.6 16.3 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding GAS PF13851.6 KPI45934.1 - 0.0031 16.9 33.3 0.047 13.0 18.2 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KPI45934.1 - 0.0044 17.3 37.5 0.14 12.4 15.0 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 KPI45934.1 - 0.0049 17.1 25.1 0.0049 17.1 25.1 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KPI45934.1 - 0.0049 16.9 17.7 0.14 12.2 4.3 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) APG6_N PF17675.1 KPI45934.1 - 0.0069 16.9 42.3 0.059 13.9 17.7 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KPI45934.1 - 0.0072 16.4 40.7 0.029 14.4 16.4 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein WXG100 PF06013.12 KPI45934.1 - 0.0092 16.2 16.6 0.17 12.1 3.4 3.3 3 0 0 3 3 3 2 Proteins of 100 residues with WXG CEP63 PF17045.5 KPI45934.1 - 0.012 15.6 28.1 0.014 15.3 28.1 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF3450 PF11932.8 KPI45934.1 - 0.012 15.0 31.8 0.17 11.2 13.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 KPI45934.1 - 0.012 15.4 31.4 0.97 9.1 11.0 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 MAD PF05557.13 KPI45934.1 - 0.015 13.7 32.0 0.019 13.3 32.0 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein BST2 PF16716.5 KPI45934.1 - 0.017 15.7 11.5 0.017 15.7 11.5 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 KPI45934.1 - 0.024 13.6 35.3 0.07 12.0 14.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KPI45934.1 - 0.024 14.6 8.7 0.024 14.6 8.7 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3086 PF11285.8 KPI45934.1 - 0.026 13.6 15.6 0.017 14.2 13.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Sipho_Gp157 PF05565.11 KPI45934.1 - 0.048 13.7 22.5 0.089 12.8 7.4 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 KASH_CCD PF14662.6 KPI45934.1 - 0.081 12.8 34.0 0.26 11.1 30.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 KPI45934.1 - 0.088 13.2 21.1 1.6 9.2 4.9 4.2 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KPI45934.1 - 0.1 12.8 27.7 0.17 12.1 1.7 4.1 1 1 3 4 4 4 0 Haemolysin XhlA Rab5-bind PF09311.11 KPI45934.1 - 0.1 11.9 28.5 0.04 13.3 20.0 2.0 1 1 1 2 2 2 0 Rabaptin-like protein HMMR_N PF15905.5 KPI45934.1 - 0.11 12.0 30.9 0.16 11.4 30.9 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 KPI45934.1 - 0.16 12.3 25.2 0.78 10.1 2.2 3.4 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.19 KPI45934.1 - 0.17 11.7 40.1 0.28 10.9 18.1 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DASH_Dam1 PF08653.10 KPI45934.1 - 0.22 11.3 8.3 0.76 9.6 0.4 3.5 3 1 1 4 4 3 0 DASH complex subunit Dam1 DUF812 PF05667.11 KPI45934.1 - 0.38 9.6 31.4 0.49 9.2 31.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 KPI45934.1 - 0.4 11.1 42.5 1.2 9.6 5.8 4.2 1 1 3 4 4 4 0 Cell division protein ZapB Uso1_p115_C PF04871.13 KPI45934.1 - 0.55 10.6 38.1 2.5 8.5 15.4 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 KPI45934.1 - 0.57 10.5 29.0 0.18 12.0 1.9 5.1 3 2 2 5 5 5 0 Homeobox associated leucine zipper Hemagglutinin PF00509.18 KPI45934.1 - 0.58 8.5 10.9 0.12 10.7 6.6 1.8 1 1 0 2 2 2 0 Haemagglutinin DUF4201 PF13870.6 KPI45934.1 - 0.69 9.6 31.0 5 6.8 10.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 KPI45934.1 - 0.7 9.9 40.4 4 7.5 13.4 3.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 KPI45934.1 - 0.74 9.9 31.8 4.2 7.5 11.3 3.1 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KPI45934.1 - 0.76 10.2 30.2 1.2 9.5 30.2 1.4 1 1 0 1 1 1 0 Fez1 Lebercilin PF15619.6 KPI45934.1 - 0.8 9.3 38.2 11 5.7 16.0 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 KPI45934.1 - 0.84 9.9 32.1 23 5.3 9.5 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 KPI45934.1 - 1 9.6 30.4 5.1 7.4 2.4 4.2 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II LPD39 PF18858.1 KPI45934.1 - 1.1 9.4 20.7 3.2 7.8 5.0 2.1 1 1 1 2 2 2 0 Large polyvalent protein associated domain 39 DUF724 PF05266.14 KPI45934.1 - 1.4 8.7 29.0 0.85 9.4 10.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF465 PF04325.13 KPI45934.1 - 1.6 8.8 21.2 5.2 7.2 0.3 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF465) Laminin_II PF06009.12 KPI45934.1 - 1.6 8.7 22.6 0.17 11.9 5.3 2.1 1 1 1 2 2 2 0 Laminin Domain II Qua1 PF16274.5 KPI45934.1 - 2 8.3 7.6 0.15 12.0 0.8 2.6 3 0 0 3 3 2 0 Qua1 domain STAT_alpha PF01017.20 KPI45934.1 - 2.5 8.0 24.8 0.2 11.6 5.0 2.5 1 1 1 2 2 2 0 STAT protein, all-alpha domain bZIP_2 PF07716.15 KPI45934.1 - 2.8 8.1 35.4 0.67 10.1 1.5 5.5 2 2 4 6 6 6 0 Basic region leucine zipper HOOK PF05622.12 KPI45934.1 - 2.9 5.9 33.9 0.42 8.7 22.0 1.9 1 1 1 2 2 2 0 HOOK protein DivIC PF04977.15 KPI45934.1 - 4.2 7.2 33.8 0.85 9.4 4.2 4.3 2 1 2 4 4 4 0 Septum formation initiator Fib_alpha PF08702.10 KPI45934.1 - 4.3 7.5 21.7 1.5 9.0 6.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CtIP_N PF10482.9 KPI45934.1 - 5.5 7.1 27.5 1.6 8.8 7.0 3.1 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Cep57_MT_bd PF06657.13 KPI45934.1 - 5.6 7.5 25.9 0.45 11.0 3.1 3.9 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 kleA_kleC PF17383.2 KPI45934.1 - 5.7 7.4 16.8 13 6.2 1.1 3.2 1 1 2 3 3 3 0 Uncharacterized KorC regulated protein A DUF3584 PF12128.8 KPI45934.1 - 5.7 4.3 31.8 15 2.9 31.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 KPI45934.1 - 5.8 6.4 20.0 8 5.9 20.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TRAF_BIRC3_bd PF16673.5 KPI45934.1 - 5.8 6.8 16.8 3.6 7.5 1.2 3.8 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Mod_r PF07200.13 KPI45934.1 - 6 7.0 31.7 9.2 6.4 6.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT46_B_C PF12317.8 KPI45934.1 - 8.1 6.1 14.6 0.73 9.5 8.2 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal V_ATPase_I PF01496.19 KPI45934.1 - 8.5 4.1 25.4 0.29 9.0 9.4 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Glyco_hydro_47 PF01532.20 KPI45935.1 - 1.7e-149 498.6 0.2 2.5e-149 498.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 bZIP_2 PF07716.15 KPI45937.1 - 1.4e-05 25.1 7.3 2.3e-05 24.4 7.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KPI45937.1 - 0.022 15.3 5.1 0.038 14.5 5.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Arrestin_N PF00339.29 KPI45938.1 - 4.4e-12 46.3 0.1 1.1e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KPI45938.1 - 0.18 10.8 0.0 0.79 8.7 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 IBR PF01485.21 KPI45939.1 - 0.006 16.8 8.3 0.006 16.8 8.3 4.7 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain INSIG PF07281.12 KPI45940.1 - 5.2e-21 75.3 0.0 7.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Glyco_hydro_16 PF00722.21 KPI45941.1 - 4.9e-42 143.4 4.3 8e-42 142.7 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF423 PF04241.15 KPI45943.1 - 1.7e-13 50.6 1.0 3.3e-13 49.6 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) RhoGAP PF00620.27 KPI45944.1 - 4.4e-13 49.3 0.5 9.5e-13 48.2 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KPI45944.1 - 3.7e-10 39.7 0.0 7.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KPI45944.1 - 1.1e-06 28.8 0.0 2.9e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain IGR PF09597.10 KPI45945.1 - 1.3e-21 76.5 1.8 1.3e-21 76.5 1.8 1.6 2 0 0 2 2 2 1 IGR protein motif Amidase PF01425.21 KPI45946.1 - 5.4e-69 233.3 0.1 4.9e-66 223.5 0.0 2.1 2 0 0 2 2 2 2 Amidase WD40 PF00400.32 KPI45947.1 - 8.2e-22 77.1 27.7 0.0096 16.8 0.1 11.0 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI45947.1 - 2e-11 44.0 0.6 0.02 15.2 0.0 6.2 4 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KPI45947.1 - 0.0033 16.5 0.7 1.3 7.9 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KPI45947.1 - 0.24 11.4 3.8 20 5.3 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat CAP PF00188.26 KPI45948.1 - 1.6e-17 64.5 0.5 2.8e-17 63.7 0.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MCM PF00493.23 KPI45949.1 - 4.8e-103 343.1 0.0 7.6e-103 342.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_N PF14551.6 KPI45949.1 - 1.3e-20 73.9 0.5 3e-20 72.7 0.5 1.6 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KPI45949.1 - 3.4e-19 69.1 0.7 9.3e-19 67.6 0.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KPI45949.1 - 4.8e-19 68.5 0.8 4.5e-17 62.1 0.8 2.3 1 1 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KPI45949.1 - 4.6e-07 29.4 0.0 5.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KPI45949.1 - 5.7e-06 26.4 0.0 2.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KPI45949.1 - 0.00046 20.0 0.1 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 KPI45949.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MutS_V PF00488.21 KPI45950.1 - 3.1e-58 196.9 0.1 5.9e-58 196.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KPI45950.1 - 2.2e-29 103.0 0.7 2.2e-29 103.0 0.7 2.4 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 KPI45950.1 - 3.2e-09 37.2 0.1 9.6e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KPI45950.1 - 5.9e-09 36.2 0.0 1.4e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 KPI45950.1 - 0.0078 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Med12-PQL PF12144.8 KPI45950.1 - 0.035 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain DNA_pol3_delta PF06144.13 KPI45950.1 - 0.048 13.4 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RhoGAP PF00620.27 KPI45952.1 - 2.3e-40 137.9 0.9 5e-40 136.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KPI45952.1 - 6.2e-14 52.4 0.0 1.2e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 PH domain RSN1_7TM PF02714.15 KPI45953.1 - 4.4e-76 255.8 21.6 1.2e-75 254.3 21.6 1.8 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KPI45953.1 - 7.6e-42 143.5 0.0 1.2e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KPI45953.1 - 7.5e-37 126.5 1.4 7.5e-37 126.5 1.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Isochorismatase PF00857.20 KPI45954.1 - 9.6e-23 81.2 0.2 1.2e-22 81.0 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family SET PF00856.28 KPI45956.1 - 2.7e-10 40.9 2.1 6.4e-09 36.4 0.1 2.9 2 1 0 3 3 3 2 SET domain BTB PF00651.31 KPI45957.1 - 3.2e-09 37.0 0.0 7.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BNR PF02012.20 KPI45958.1 - 4.6e-09 34.9 20.8 0.22 11.6 0.3 6.4 6 0 0 6 6 6 5 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KPI45958.1 - 2.2e-07 30.0 0.7 0.02 13.7 0.0 3.4 2 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KPI45958.1 - 0.00075 18.9 0.5 0.44 9.8 0.4 3.2 1 1 2 3 3 3 3 BNR repeat-like domain Mo-co_dimer PF03404.16 KPI45958.1 - 0.49 10.4 10.5 7.8 6.5 0.0 4.5 4 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain YcxB PF14317.6 KPI45959.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein UBA_4 PF14555.6 KPI45959.1 - 0.28 11.0 1.6 16 5.4 0.2 2.6 2 0 0 2 2 2 0 UBA-like domain YEATS PF03366.16 KPI45960.1 - 7.1e-17 61.2 0.2 1.2e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 YEATS family AICARFT_IMPCHas PF01808.18 KPI45961.1 - 1.8e-73 247.6 0.3 2.7e-55 187.9 0.0 2.2 2 0 0 2 2 2 2 AICARFT/IMPCHase bienzyme MGS PF02142.22 KPI45961.1 - 3.4e-23 81.6 0.0 6.2e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Ribosomal_L12_N PF16320.5 KPI45961.1 - 0.15 11.8 1.5 0.41 10.4 1.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain GFA PF04828.14 KPI45963.1 - 2.6e-18 66.1 0.3 4.6e-18 65.4 0.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 KPI45963.1 - 0.15 12.0 2.3 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Prim_Zn_Ribbon PF08273.12 KPI45963.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.1 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Sulfotransfer_4 PF17784.1 KPI45964.1 - 4.9e-45 154.0 0.0 5.8e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KPI45964.1 - 0.0018 18.7 0.0 0.071 13.5 0.0 2.4 2 0 0 2 2 2 1 Sulfotransferase family Sugar_tr PF00083.24 KPI45965.1 - 7.8e-82 275.5 21.4 9.1e-82 275.3 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI45965.1 - 2e-16 59.9 31.4 2e-16 59.9 31.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 KPI45966.1 - 1.1e-10 42.0 9.0 1.6e-09 38.3 2.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Adeno_E3_CR1 PF02440.15 KPI45967.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 ANAPC4_WD40 PF12894.7 KPI45968.1 - 4.7e-10 39.6 0.9 0.00017 21.8 0.1 5.9 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KPI45968.1 - 4.7e-05 24.1 14.3 2.5 9.1 0.6 7.9 9 1 1 10 10 10 1 WD domain, G-beta repeat TFIIF_alpha PF05793.12 KPI45968.1 - 0.13 10.8 1.9 0.22 10.1 1.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IMUP PF15761.5 KPI45968.1 - 2 9.1 6.4 6 7.6 6.4 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Cwf_Cwc_15 PF04889.12 KPI45968.1 - 5.9 6.5 5.7 11 5.6 5.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Fungal_trans_2 PF11951.8 KPI45969.1 - 1.6e-06 27.2 0.4 2.2e-06 26.8 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Frag1 PF10277.9 KPI45972.1 - 3.8e-47 160.7 16.9 4.3e-47 160.5 16.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2070 PF09843.9 KPI45972.1 - 4.9 5.3 10.8 5.8 5.1 10.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 KPI45973.1 - 1e-17 64.2 6.3 0.0005 20.8 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Med5 PF08689.10 KPI45974.1 - 3.2e-39 134.6 0.0 3.3e-36 124.6 0.0 2.4 2 1 0 2 2 2 2 Mediator complex subunit Med5 DUF89 PF01937.19 KPI45975.1 - 7.8e-107 357.3 1.1 8.9e-107 357.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fasciclin PF02469.22 KPI45976.1 - 1.8e-43 147.8 0.4 1.8e-26 92.9 0.5 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF348 PF03990.14 KPI45976.1 - 0.1 12.3 0.7 0.23 11.2 0.7 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain PALP PF00291.25 KPI45977.1 - 1.6e-76 257.5 0.3 2.1e-76 257.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KPI45977.1 - 1.8e-43 146.2 0.0 7.3e-21 73.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF1129 PF06570.11 KPI45979.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Trypan_PARP PF05887.11 KPI45981.1 - 0.00028 20.9 30.6 0.00052 20.0 30.6 1.5 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nodulin_late PF07127.11 KPI45981.1 - 0.0029 17.9 0.6 7.7 6.9 0.0 3.0 3 0 0 3 3 3 2 Late nodulin protein BTK PF00779.19 KPI45981.1 - 0.0038 17.0 7.8 3.1 7.7 0.2 3.2 3 0 0 3 3 3 3 BTK motif GBP_PSP PF02425.15 KPI45981.1 - 0.2 11.3 4.3 31 4.3 0.0 3.4 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide RHIM PF12721.7 KPI45981.1 - 2.3 8.8 10.7 2.9 8.5 1.2 3.2 3 1 0 3 3 3 0 RIP homotypic interaction motif Abhydrolase_3 PF07859.13 KPI45982.1 - 6.2e-41 140.6 0.0 1.7e-31 109.7 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KPI45982.1 - 2e-15 56.6 0.0 3.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KPI45982.1 - 0.0028 16.6 0.2 0.038 12.8 0.0 2.3 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KPI45982.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SUR7 PF06687.12 KPI45983.1 - 4.2e-39 134.4 17.3 5.4e-39 134.0 17.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KPI45983.1 - 0.00067 19.6 6.3 0.00067 19.6 6.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 KPI45983.1 - 0.00068 18.8 3.1 0.0007 18.7 2.0 1.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) Shisa PF13908.6 KPI45983.1 - 0.079 13.2 4.9 0.13 12.5 0.7 2.7 2 1 2 4 4 4 0 Wnt and FGF inhibitory regulator WD40 PF00400.32 KPI45984.1 - 2.7e-19 69.1 9.6 4.5e-06 27.3 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.12 KPI45984.1 - 7.2e-16 58.5 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KPI45984.1 - 0.00039 20.7 0.0 0.0093 16.3 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KPI45984.1 - 0.16 10.6 2.2 8.7 4.9 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Glycohydro_20b2 PF14845.6 KPI45985.1 - 7e-23 81.8 0.0 9.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KPI45985.1 - 6e-08 33.5 0.3 1.2e-07 32.6 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Form_Nir_trans PF01226.17 KPI45986.1 - 1.7e-52 178.1 21.3 2e-52 177.9 21.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Acetyltransf_1 PF00583.25 KPI45987.1 - 2.3e-11 43.9 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KPI45987.1 - 1.5e-06 28.2 0.1 2.2e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI45987.1 - 2.3e-06 27.5 0.1 4.4e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KPI45987.1 - 2.6e-05 24.5 0.0 4.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KPI45987.1 - 0.013 15.6 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4352 PF11611.8 KPI45987.1 - 0.07 13.4 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) Acyl_transf_3 PF01757.22 KPI45988.1 - 9.9e-27 93.9 24.1 7.4e-26 91.0 24.1 2.2 1 1 0 1 1 1 1 Acyltransferase family MscS_TM PF12794.7 KPI45988.1 - 0.011 14.7 0.2 0.011 14.7 0.2 2.6 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Proteasome PF00227.26 KPI45989.1 - 6.6e-47 159.5 0.5 7.7e-47 159.2 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Flavodoxin_1 PF00258.25 KPI45989.1 - 0.039 14.2 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin RhaA PF06134.11 KPI45992.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) Glyco_transf_20 PF00982.21 KPI45993.1 - 7.7e-138 460.1 0.1 2e-135 452.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KPI45993.1 - 2e-36 125.3 0.0 3.9e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase zf-LYAR PF08790.11 KPI45994.1 - 2e-14 53.2 3.8 2e-14 53.2 3.8 2.6 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger DUF3176 PF11374.8 KPI45995.1 - 2.8e-15 56.5 2.9 8e-15 55.0 2.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) AMP-binding PF00501.28 KPI45996.1 - 2.4e-68 230.7 0.0 3.1e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI45996.1 - 8.9e-15 55.4 0.2 2.1e-14 54.2 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_79C PF16862.5 KPI45997.1 - 6.1e-19 68.8 0.2 1.5e-18 67.6 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Beta-lactamase PF00144.24 KPI45999.1 - 3e-23 82.6 0.2 3.6e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase C2 PF00168.30 KPI46001.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF2992 PF11208.8 KPI46001.1 - 0.064 13.5 1.6 0.16 12.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Nop25 PF09805.9 KPI46002.1 - 9.1e-31 107.1 12.4 9.1e-31 107.1 12.4 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) FAM220 PF15487.6 KPI46002.1 - 0.015 15.0 0.4 0.015 15.0 0.4 1.9 2 0 0 2 2 2 0 FAM220 family Mitofilin PF09731.9 KPI46003.1 - 1.2e-125 420.8 25.1 6.2e-125 418.4 25.1 2.1 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Spidroin_N PF16763.5 KPI46003.1 - 0.08 13.0 2.1 1.1 9.3 0.0 3.1 3 1 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF3958 PF13125.6 KPI46003.1 - 1.2 9.3 11.8 2.3 8.5 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) ApoLp-III PF07464.11 KPI46003.1 - 2.4 8.2 9.9 6.8 6.8 9.9 1.8 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FapA PF03961.13 KPI46003.1 - 3.1 6.3 6.6 4.9 5.6 6.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SPX PF03105.19 KPI46003.1 - 5.2 6.9 30.9 0.058 13.3 20.1 2.2 1 1 1 2 2 2 0 SPX domain 4HB_MCP_1 PF12729.7 KPI46003.1 - 5.8 6.4 8.9 11 5.5 8.9 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Cytochrom_B562 PF07361.11 KPI46003.1 - 7 7.4 8.4 4.2 8.1 2.1 3.7 4 1 0 4 4 4 0 Cytochrome b562 Fzo_mitofusin PF04799.13 KPI46004.1 - 0.029 13.9 0.7 0.029 13.9 0.7 2.3 2 0 0 2 2 2 0 fzo-like conserved region TMF_DNA_bd PF12329.8 KPI46004.1 - 0.15 12.1 4.2 0.72 9.9 1.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KPI46004.1 - 0.31 10.9 5.5 4 7.4 1.7 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 KPI46004.1 - 2.1 8.4 13.3 2.5 8.1 0.4 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Dsl1_C PF11989.8 KPI46006.1 - 3.9e-07 30.0 0.2 1.3e-06 28.2 0.2 1.8 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal DUF2046 PF09755.9 KPI46006.1 - 0.00081 18.7 0.1 0.0017 17.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Tup_N PF08581.10 KPI46006.1 - 0.0034 17.7 0.3 0.3 11.4 0.1 3.2 2 0 0 2 2 2 1 Tup N-terminal Seryl_tRNA_N PF02403.22 KPI46006.1 - 0.16 12.3 2.9 0.6 10.4 0.4 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KPI46006.1 - 2.3 8.3 6.6 0.81 9.7 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Aldolase_II PF00596.21 KPI46007.1 - 1.8e-45 155.2 1.3 5e-45 153.7 1.3 1.7 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Transketolase_N PF00456.21 KPI46008.1 - 3.7e-122 407.5 0.0 5.5e-122 406.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KPI46008.1 - 3.1e-41 141.0 0.2 6.6e-41 139.9 0.2 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KPI46008.1 - 4.4e-06 26.6 0.0 1.4e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KPI46008.1 - 1.2e-05 24.6 0.0 3.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_C PF09363.10 KPI46008.1 - 0.051 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 XFP C-terminal domain Melibiase_2 PF16499.5 KPI46009.1 - 4.3e-47 160.6 2.7 6.9e-32 110.8 0.6 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KPI46009.1 - 2.6e-08 33.8 0.7 6.5e-08 32.5 0.7 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KPI46009.1 - 0.00016 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Melibiase p450 PF00067.22 KPI46010.1 - 6.3e-60 203.2 0.0 8.7e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.25 KPI46011.1 - 9.2e-24 84.1 1.5 1.2e-15 57.9 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KPI46011.1 - 3.4e-15 56.2 0.2 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KPI46011.1 - 5.4e-08 33.2 2.1 0.0033 17.6 0.9 3.8 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KPI46011.1 - 8.4e-08 32.5 0.4 4e-05 23.8 0.3 3.1 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_6 PF18029.1 KPI46011.1 - 0.0033 18.2 0.1 0.055 14.3 0.2 2.3 2 0 0 2 2 2 1 Glyoxalase-like domain Myb_DNA-bind_6 PF13921.6 KPI46012.1 - 7.8e-14 51.7 0.0 2.3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KPI46012.1 - 1.8e-11 44.2 0.7 1.8e-11 44.2 0.7 3.4 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 KPI46012.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M19 PF01244.21 KPI46013.1 - 4.6e-94 315.1 0.0 5.4e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amino_oxidase PF01593.24 KPI46014.1 - 2.2e-36 126.2 0.0 2e-35 122.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KPI46014.1 - 1.8e-10 40.9 0.0 6.3e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KPI46014.1 - 0.00014 21.3 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KPI46014.1 - 0.00037 19.3 0.2 0.0007 18.4 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KPI46014.1 - 0.00066 19.0 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KPI46014.1 - 0.027 13.5 0.5 0.042 12.9 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KPI46014.1 - 0.035 13.3 0.0 0.089 12.0 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KPI46014.1 - 0.079 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KPI46014.1 - 0.12 13.0 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Herpes_UL32 PF06070.11 KPI46014.1 - 0.17 9.6 0.0 0.24 9.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Thi4 PF01946.17 KPI46014.1 - 0.21 10.8 0.2 0.34 10.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family GTP_EFTU PF00009.27 KPI46015.1 - 3.6e-20 72.3 0.5 4.3e-19 68.8 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KPI46015.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KPI46015.1 - 0.014 15.3 0.2 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KPI46015.1 - 0.065 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Dynamin family CTP_transf_like PF01467.26 KPI46016.1 - 0.0037 17.5 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KPI46016.1 - 0.19 11.6 1.2 0.38 10.6 0.9 1.7 1 1 0 1 1 1 0 FAD synthetase BSD PF03909.17 KPI46017.1 - 5.6e-19 67.9 0.2 1e-18 67.0 0.2 1.5 1 0 0 1 1 1 1 BSD domain Peptidase_M24 PF00557.24 KPI46018.1 - 1.2e-36 126.4 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Sorting_nexin PF03700.13 KPI46018.1 - 2.5 8.7 5.6 2 9.0 3.7 1.7 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain DUF3446 PF11928.8 KPI46019.1 - 5.9 7.3 10.6 1.7 9.0 0.2 3.3 3 1 1 4 4 4 0 Early growth response N-terminal domain Sugar_tr PF00083.24 KPI46020.1 - 1.8e-34 119.4 37.0 4.2e-18 65.5 21.5 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KPI46020.1 - 1.2e-05 24.5 52.1 0.0072 15.3 22.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KPI46021.1 - 3.9e-56 190.7 0.0 4.7e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.24 KPI46022.1 - 3.3e-27 95.3 0.0 4.7e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 KPI46023.1 - 2.6e-07 29.9 46.3 0.0028 16.7 44.3 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Aft1_HRA PF11786.8 KPI46023.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Aft1 HRA domain Tom6 PF17112.5 KPI46023.1 - 2.4 7.8 7.4 2.3 7.8 0.3 3.5 4 0 0 4 4 4 0 Mitochondrial import receptor subunit Tom6, fungal Transp_inhibit PF18791.1 KPI46024.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain FAA_hydrolase PF01557.18 KPI46025.1 - 3.4e-50 170.7 0.0 4.4e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KPI46025.1 - 1.2e-27 96.2 0.0 8.6e-27 93.4 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal RhoGAP PF00620.27 KPI46028.1 - 1.1e-29 103.2 0.0 1.8e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C48 PF02902.19 KPI46029.1 - 2.5e-15 56.9 0.2 7.9e-15 55.3 0.3 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KPI46029.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Methyltransf_4 PF02390.17 KPI46030.1 - 2.1e-41 141.2 0.0 3.6e-40 137.2 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KPI46030.1 - 0.0013 19.4 0.0 0.0046 17.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KPI46030.1 - 0.026 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KPI46030.1 - 0.044 14.5 0.0 0.092 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KPI46030.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HA2 PF04408.23 KPI46030.1 - 0.18 12.1 0.3 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Helicase associated domain (HA2) Fungal_trans PF04082.18 KPI46031.1 - 0.017 14.2 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain EVE PF01878.18 KPI46032.1 - 7.1e-47 159.1 0.3 7.1e-47 159.1 0.3 2.0 2 0 0 2 2 2 1 EVE domain LSM PF01423.22 KPI46033.1 - 1.7e-21 75.7 0.0 1.8e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain HD PF01966.22 KPI46034.1 - 7.4e-05 23.0 0.0 9.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 HD domain SWI-SNF_Ssr4 PF08549.10 KPI46035.1 - 7.6e-150 500.9 32.0 1.1e-79 269.0 19.0 3.2 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) kleA_kleC PF17383.2 KPI46035.1 - 0.2 12.0 1.5 0.53 10.6 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A tRNA-synt_1b PF00579.25 KPI46036.1 - 1.7e-62 211.4 0.0 2.1e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) End_N_terminal PF12218.8 KPI46036.1 - 0.036 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase zf-C2H2 PF00096.26 KPI46037.1 - 7.3e-10 38.8 21.1 0.00056 20.2 1.7 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type NACHT PF05729.12 KPI46037.1 - 1.1e-09 38.4 0.1 2.3e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KPI46037.1 - 1.4e-08 35.3 0.0 9.6e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KPI46037.1 - 4.4e-06 27.0 0.0 1.8e-05 25.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain zf-C2H2_4 PF13894.6 KPI46037.1 - 1.8e-05 25.2 13.2 0.038 14.8 1.0 4.5 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.7 KPI46037.1 - 0.00018 21.7 8.8 0.69 10.4 0.4 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KPI46037.1 - 0.0022 17.7 0.2 0.0083 15.9 0.2 2.0 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KPI46037.1 - 0.0026 17.6 1.7 0.1 12.5 0.3 2.9 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KPI46037.1 - 0.0049 17.6 2.9 1.1 10.0 0.4 3.5 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats DUF2075 PF09848.9 KPI46037.1 - 0.011 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KPI46037.1 - 0.014 15.9 0.1 0.051 14.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) zf-H2C2_2 PF13465.6 KPI46037.1 - 0.035 14.6 0.5 0.035 14.6 0.5 5.2 6 0 0 6 6 5 0 Zinc-finger double domain NTPase_1 PF03266.15 KPI46037.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 KPI46037.1 - 0.072 13.6 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.8 KPI46037.1 - 0.3 11.4 18.7 0.27 11.6 1.7 4.1 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-DNL PF05180.12 KPI46037.1 - 0.94 9.5 3.2 13 5.8 1.0 3.0 3 0 0 3 3 3 0 DNL zinc finger Actin_micro PF17003.5 KPI46037.1 - 2 7.5 3.7 22 4.1 0.5 2.4 1 1 1 2 2 2 0 Putative actin-like family Aminotran_1_2 PF00155.21 KPI46039.1 - 1e-43 150.0 0.0 1.2e-43 149.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KPI46039.1 - 1e-10 41.1 0.0 4.4e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KPI46039.1 - 7.4e-09 34.6 0.0 1.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KPI46039.1 - 8.7e-09 35.1 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KPI46039.1 - 0.00035 20.0 0.0 0.00085 18.7 0.0 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 KPI46039.1 - 0.033 13.0 0.1 0.096 11.5 0.1 1.6 1 1 0 1 1 1 0 Allinase RTA1 PF04479.13 KPI46040.1 - 2.6e-69 233.0 6.6 3.5e-69 232.6 6.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Rhomboid PF01694.22 KPI46040.1 - 0.47 10.4 11.8 0.067 13.2 1.0 2.8 1 1 2 3 3 3 0 Rhomboid family DUF5367 PF17329.2 KPI46040.1 - 0.52 10.5 5.8 0.27 11.4 0.2 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5367) DUF423 PF04241.15 KPI46040.1 - 3.5 7.9 7.6 0.57 10.4 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF423) CorA PF01544.18 KPI46041.1 - 0.002 17.5 0.1 0.002 17.5 0.1 2.2 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein ADIP PF11559.8 KPI46041.1 - 0.12 12.5 0.6 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PK PF00224.21 KPI46042.1 - 5.1e-167 555.1 2.4 6.4e-167 554.8 2.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KPI46042.1 - 7.6e-35 119.7 0.0 2.1e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KPI46042.1 - 0.00013 21.2 0.2 0.00024 20.3 0.2 1.4 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Calcipressin PF04847.12 KPI46042.1 - 0.033 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 Calcipressin IMPDH PF00478.25 KPI46042.1 - 0.043 12.8 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain SNF5 PF04855.12 KPI46043.1 - 3.4e-59 200.5 0.2 5.3e-58 196.6 0.2 2.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Totivirus_coat PF05518.11 KPI46043.1 - 5 5.0 7.3 7.4 4.5 7.3 1.2 1 0 0 1 1 1 0 Totivirus coat protein TMEM154 PF15102.6 KPI46044.1 - 0.0012 18.8 1.3 0.0049 16.8 0.0 2.5 2 0 0 2 2 2 1 TMEM154 protein family DNA_pol_A_exo1 PF01612.20 KPI46044.1 - 0.085 12.6 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 3'-5' exonuclease DUF3094 PF11293.8 KPI46044.1 - 1.1 9.1 3.2 2.5 7.9 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Glycophorin_A PF01102.18 KPI46044.1 - 1.8 8.8 4.8 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Glycophorin A GREB1 PF15782.5 KPI46044.1 - 6 3.8 15.6 9.5 3.2 15.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HET PF06985.11 KPI46045.1 - 9.1e-24 84.5 0.1 5.9e-23 81.8 0.1 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KPI46046.1 - 4.8e-31 108.0 29.0 1.1e-30 106.7 28.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KPI46046.1 - 4.3 7.7 13.5 36 4.8 0.4 5.1 4 1 2 6 6 6 0 Phage holin family Hol44, in holin superfamily V PMM PF03332.13 KPI46047.1 - 1.5e-96 322.5 0.0 1.7e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KPI46047.1 - 0.0012 18.7 0.0 0.026 14.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HisG PF01634.18 KPI46049.1 - 8.3e-57 191.6 0.1 1.4e-56 190.9 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KPI46049.1 - 3.2e-27 94.5 0.6 7.9e-27 93.2 0.6 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KPI46049.1 - 0.00021 21.3 0.1 0.00037 20.5 0.1 1.5 1 0 0 1 1 1 1 NMT1/THI5 like DnaJ PF00226.31 KPI46050.1 - 1.1e-20 73.5 2.0 1.8e-20 72.8 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.6 KPI46050.1 - 0.01 15.6 8.3 0.029 14.2 8.3 1.7 1 0 0 1 1 1 0 Glycine-zipper domain DUF456 PF04306.13 KPI46050.1 - 0.056 13.7 1.3 0.087 13.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SARAF PF06682.12 KPI46050.1 - 0.13 11.9 2.8 0.2 11.3 2.8 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1269 PF06897.12 KPI46050.1 - 0.16 12.3 1.4 0.35 11.2 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.6 KPI46050.1 - 0.54 10.3 15.6 1.3 9.1 15.3 1.8 1 1 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KPI46050.1 - 0.63 9.9 17.0 1.8 8.5 6.1 2.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 KPI46050.1 - 1.6 8.9 8.9 4.4 7.5 8.9 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 KPI46050.1 - 1.9 8.3 15.7 2.7 7.8 13.6 2.2 1 1 1 2 2 2 0 YMGG-like Gly-zipper Sugar_tr PF00083.24 KPI46051.1 - 1.2e-73 248.5 22.4 1.6e-73 248.2 22.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KPI46051.1 - 3.7e-21 75.4 19.4 3.7e-21 75.4 19.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily SLATT_fungal PF18142.1 KPI46051.1 - 1.3e-19 70.3 1.8 1.3e-19 70.3 1.8 2.5 2 1 1 3 3 3 1 SMODS and SLOG-associating 2TM effector domain TRI12 PF06609.13 KPI46051.1 - 0.0025 16.3 3.5 0.0025 16.3 3.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Macoilin PF09726.9 KPI46052.1 - 0.55 8.7 6.3 0.75 8.3 6.3 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KPI46053.1 - 4.6e-31 108.0 16.7 5.5e-31 107.8 16.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4494 PF14902.6 KPI46053.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) SSF PF00474.17 KPI46054.1 - 5.1e-19 68.4 20.5 8.6e-19 67.7 20.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family CoA_binding_3 PF13727.6 KPI46054.1 - 0.049 13.6 0.5 0.23 11.5 0.5 2.2 1 0 0 1 1 1 0 CoA-binding domain zf-RING_2 PF13639.6 KPI46055.1 - 1.5e-06 28.4 5.0 4.4e-06 26.9 5.0 1.8 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KPI46055.1 - 1.1e-05 24.9 4.9 1.1e-05 24.9 4.9 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KPI46055.1 - 0.00034 20.4 4.2 0.00079 19.2 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KPI46055.1 - 0.00064 19.6 3.7 0.0029 17.5 3.8 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KPI46055.1 - 0.0017 18.2 3.8 0.0046 16.8 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KPI46055.1 - 0.0018 18.0 2.3 0.0056 16.4 2.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KPI46055.1 - 0.002 17.9 2.6 0.0048 16.7 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KPI46055.1 - 0.012 15.7 2.6 0.012 15.7 2.6 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Dopey_N PF04118.14 KPI46055.1 - 0.021 13.9 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal zf-ANAPC11 PF12861.7 KPI46055.1 - 0.026 14.6 5.3 0.15 12.1 5.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KPI46055.1 - 0.071 13.1 5.8 0.19 11.7 5.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 KPI46055.1 - 0.14 12.0 9.2 0.11 12.4 6.1 2.3 2 0 0 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 KPI46055.1 - 0.34 11.2 6.3 1.3 9.4 6.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 KPI46055.1 - 0.39 10.9 8.6 1.4 9.1 8.6 2.0 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KPI46055.1 - 1.1 9.5 4.3 3.1 8.0 4.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING STAT_alpha PF01017.20 KPI46056.1 - 0.062 13.2 0.2 13 5.6 0.0 2.4 2 0 0 2 2 2 0 STAT protein, all-alpha domain Fib_alpha PF08702.10 KPI46056.1 - 0.25 11.5 0.6 1.2 9.3 0.0 2.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family AMP-binding PF00501.28 KPI46057.1 - 6.5e-62 209.5 0.0 9.1e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KPI46057.1 - 1.1e-09 39.1 0.1 2.4e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidohydro_2 PF04909.14 KPI46058.1 - 6.6e-37 127.9 0.0 8.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF5075 PF16825.5 KPI46058.1 - 0.00046 19.9 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 IGP family C-type lectin domain DEAD PF00270.29 KPI46059.1 - 1.3e-31 109.7 0.1 2e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KPI46059.1 - 2.3e-17 63.3 0.0 1e-16 61.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KPI46059.1 - 7.8e-07 29.2 0.0 6.5e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Isochorismatase PF00857.20 KPI46060.1 - 2.6e-31 109.1 0.0 3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NAPRTase PF04095.16 KPI46061.1 - 6.9e-56 189.5 0.1 7e-30 104.4 0.1 2.1 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KPI46061.1 - 1.7e-34 118.9 0.0 2.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ThiF PF00899.21 KPI46062.1 - 1.3e-49 168.8 0.0 4.7e-49 167.0 0.0 1.9 2 0 0 2 2 2 1 ThiF family Rhodanese PF00581.20 KPI46062.1 - 0.00033 21.1 0.0 0.00078 19.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.16 KPI46062.1 - 0.17 11.5 0.4 0.47 10.1 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Aa_trans PF01490.18 KPI46063.1 - 3.3e-82 276.4 30.7 3.8e-82 276.2 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Transglut_core PF01841.19 KPI46064.1 - 7.8e-16 58.5 1.4 1.7e-15 57.5 1.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 KPI46064.1 - 4.6e-14 52.3 1.2 9.2e-14 51.4 1.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain YdjO PF14169.6 KPI46064.1 - 0.094 12.5 0.5 4 7.2 0.2 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO Prefoldin_3 PF13758.6 KPI46066.1 - 1.6e-22 79.4 1.3 2.8e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KPI46066.1 - 2.1e-19 70.2 0.1 2.1e-19 70.2 0.1 4.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3835) CCDC66 PF15236.6 KPI46066.1 - 0.12 12.2 2.1 0.34 10.8 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 ATP-grasp_2 PF08442.10 KPI46067.1 - 9.4e-61 204.9 0.0 1.5e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KPI46067.1 - 3.8e-18 65.7 1.9 9.1e-18 64.5 1.9 1.7 1 1 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KPI46067.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain TMEM171 PF15471.6 KPI46068.1 - 2 7.3 4.8 3.2 6.6 4.8 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 PhyH PF05721.13 KPI46069.1 - 1.2e-23 84.5 0.0 2.3e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KPI46069.1 - 0.03 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Velvet PF11754.8 KPI46070.1 - 1.2e-70 238.3 0.0 1.2e-70 238.3 0.0 1.6 2 0 0 2 2 2 1 Velvet factor MFS_1 PF07690.16 KPI46071.1 - 1e-29 103.6 27.6 1.2e-29 103.4 27.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KPI46071.1 - 3.1e-06 26.7 2.5 3.1e-06 26.7 2.5 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KPI46071.1 - 9.3e-06 24.7 0.0 0.0059 15.5 0.0 2.4 1 1 1 2 2 2 2 MFS_1 like family PRA1 PF03208.19 KPI46072.1 - 3.9e-38 130.3 0.7 4.6e-38 130.1 0.7 1.1 1 0 0 1 1 1 1 PRA1 family protein SLAC1 PF03595.17 KPI46073.1 - 3.5e-81 273.0 54.7 4e-81 272.8 54.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COX7a PF02238.15 KPI46073.1 - 1.3 9.4 4.7 1.3 9.4 0.1 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII DAHP_synth_1 PF00793.20 KPI46074.1 - 5.4e-98 327.2 0.0 9.2e-98 326.5 0.0 1.3 1 0 0 1 1 1 1 DAHP synthetase I family Peptidase_M16_C PF05193.21 KPI46074.1 - 3.7e-22 79.2 0.0 1.2e-19 71.1 0.0 2.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KPI46074.1 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) bZIP_1 PF00170.21 KPI46075.1 - 0.00035 20.6 2.3 0.00098 19.2 2.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor Zn_clus PF00172.18 KPI46075.1 - 0.019 15.1 8.8 0.059 13.5 8.8 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 KPI46075.1 - 0.077 13.1 5.0 0.59 10.3 4.8 2.5 1 1 0 1 1 1 0 Basic region leucine zipper zf-C2H2 PF00096.26 KPI46075.1 - 0.13 12.8 3.6 3.9 8.1 0.5 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KPI46075.1 - 0.76 10.8 4.6 20 6.3 0.5 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_2 PF13639.6 KPI46076.1 - 1.3e-07 31.8 4.3 1.3e-07 31.8 4.3 1.8 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KPI46076.1 - 0.00038 20.6 5.4 0.00038 20.6 5.4 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 KPI46076.1 - 0.0041 17.0 2.3 0.0041 17.0 2.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 SWIM PF04434.17 KPI46076.1 - 0.011 15.4 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger zf-ANAPC11 PF12861.7 KPI46076.1 - 0.016 15.2 2.3 0.016 15.2 2.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KPI46076.1 - 0.056 13.2 5.7 0.12 12.2 5.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KPI46076.1 - 0.064 13.2 6.5 0.14 12.1 6.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 KPI46076.1 - 0.57 10.2 4.2 1.9 8.5 4.3 1.9 1 1 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.22 KPI46076.1 - 0.76 9.7 6.3 1.5 8.8 2.0 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KPI46076.1 - 1.6 9.1 6.4 0.16 12.3 1.5 1.9 2 0 0 2 2 2 0 RING-like domain SCRL PF06876.12 KPI46076.1 - 2.5 8.3 7.3 0.74 10.0 1.3 2.3 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein RINGv PF12906.7 KPI46076.1 - 7.8 6.7 11.8 0.65 10.2 6.9 1.8 2 0 0 2 2 2 0 RING-variant domain Proteasome PF00227.26 KPI46077.1 - 1.3e-32 112.9 0.4 8.9e-32 110.1 0.4 1.9 1 1 0 1 1 1 1 Proteasome subunit Fungal_trans_2 PF11951.8 KPI46079.1 - 2e-07 30.2 1.2 2e-07 30.2 1.2 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KPI46079.1 - 0.0017 18.4 2.9 0.0041 17.2 2.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.26 KPI46080.1 - 3.4e-20 72.6 0.0 6.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KPI46080.1 - 1e-15 57.9 1.4 3.4e-08 33.6 0.1 3.6 3 1 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 KPI46080.1 - 1.3e-05 25.1 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain LPP PF04728.13 KPI46080.1 - 0.072 13.5 0.4 0.16 12.4 0.4 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Tyrosinase PF00264.20 KPI46081.1 - 8.5e-19 68.7 1.8 1.4e-18 68.0 1.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Pro_isomerase PF00160.21 KPI46082.1 - 1.6e-49 168.2 0.0 3e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KPI46082.1 - 1.6e-09 38.2 0.1 0.011 16.6 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat G_glu_transpept PF01019.21 KPI46083.1 - 2e-162 541.5 0.7 2.3e-162 541.3 0.7 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF4453 PF14627.6 KPI46083.1 - 0.15 12.2 0.1 34 4.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4453) WD40 PF00400.32 KPI46084.1 - 1e-10 42.0 8.0 0.00045 21.0 0.3 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KPI46084.1 - 1.2e-05 25.5 0.0 0.027 14.8 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pro-kuma_activ PF09286.11 KPI46085.1 - 2.9e-41 141.1 0.1 5.1e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KPI46085.1 - 2.8e-08 33.4 0.0 6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Subtilase family YL1 PF05764.13 KPI46086.1 - 0.00025 21.3 4.6 0.0005 20.3 4.6 1.5 1 0 0 1 1 1 1 YL1 nuclear protein PBP1_TM PF14812.6 KPI46086.1 - 1.5 9.2 7.8 4.6 7.7 7.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KPI46086.1 - 3.4 5.6 6.0 5.1 5.1 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KPI46086.1 - 5.1 6.8 6.0 15 5.2 6.0 1.8 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_20 PF00728.22 KPI46088.1 - 4.3e-87 292.8 0.1 5.1e-87 292.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DnaJ PF00226.31 KPI46089.1 - 0.0045 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 KPI46090.1 - 1.9e-48 165.2 46.3 1.8e-47 162.0 46.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KPI46090.1 - 4.5e-14 51.8 16.6 6.1e-14 51.4 16.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CN_hydrolase PF00795.22 KPI46092.1 - 7.5e-43 146.7 0.0 8.8e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA-synt_1 PF00133.22 KPI46093.1 - 1.1e-157 525.9 0.0 1.4e-157 525.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KPI46093.1 - 1.7e-22 80.0 0.1 3.3e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KPI46093.1 - 6.3e-21 74.6 0.0 9e-13 47.7 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KPI46093.1 - 0.0049 16.2 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KPI46093.1 - 1.7 8.6 4.2 1.1 9.2 0.3 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS IncE PF17627.2 KPI46094.1 - 0.12 12.4 3.3 0.078 13.0 1.0 1.9 2 0 0 2 2 2 0 Inclusion membrane protein E S-methyl_trans PF02574.16 KPI46095.1 - 5.3e-49 167.4 0.0 6e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Aldo_ket_red PF00248.21 KPI46096.1 - 3.2e-45 154.6 0.0 4.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_11 PF00457.17 KPI46098.1 - 1.8e-77 259.0 20.8 2.2e-77 258.7 20.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF1510 PF07423.11 KPI46098.1 - 0.017 15.2 0.9 0.044 13.9 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Acetyltransf_1 PF00583.25 KPI46099.1 - 1.4e-11 44.6 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KPI46099.1 - 9.2e-05 22.8 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KPI46099.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KPI46099.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein GSH-S_N PF02951.14 KPI46099.1 - 0.041 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain ABC_membrane PF00664.23 KPI46100.1 - 6.6e-55 186.7 26.4 1.1e-37 130.2 15.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KPI46100.1 - 3.2e-45 154.0 0.0 9.2e-26 91.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KPI46100.1 - 6.9e-08 32.2 3.4 0.0029 17.1 1.5 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KPI46100.1 - 2.4e-06 27.6 0.2 0.014 15.5 0.1 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KPI46100.1 - 1.6e-05 24.9 0.2 0.31 10.8 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KPI46100.1 - 3.4e-05 24.3 0.1 0.091 13.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KPI46100.1 - 9e-05 21.8 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KPI46100.1 - 9.8e-05 22.0 0.4 0.5 10.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KPI46100.1 - 0.0009 19.2 0.4 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KPI46100.1 - 0.0019 18.4 0.9 1.7 8.9 0.1 3.2 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KPI46100.1 - 0.0028 16.7 1.2 0.81 8.6 0.3 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KPI46100.1 - 0.0037 17.0 0.8 3.8 7.1 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 KPI46100.1 - 0.0051 16.6 4.0 0.86 9.3 0.7 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KPI46100.1 - 0.016 15.7 0.8 3.3 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KPI46100.1 - 0.017 14.9 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KPI46100.1 - 0.019 15.0 4.1 0.62 10.1 0.2 2.7 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KPI46100.1 - 0.032 14.5 0.2 12 6.1 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KPI46100.1 - 0.048 13.3 0.6 0.3 10.7 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 KPI46100.1 - 0.058 13.3 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 KPI46100.1 - 0.068 12.9 1.6 5.2 6.8 0.5 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KPI46100.1 - 0.077 12.9 0.5 0.66 9.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KPI46100.1 - 0.086 13.3 12.8 0.45 11.0 0.0 3.7 4 0 0 4 4 3 0 AAA domain TrwB_AAD_bind PF10412.9 KPI46100.1 - 0.086 11.7 2.2 0.87 8.4 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KPI46100.1 - 0.088 11.9 1.0 1.5 7.8 0.1 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_7 PF12775.7 KPI46100.1 - 0.15 11.5 0.2 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KPI46100.1 - 0.16 11.9 0.9 2.2 8.2 0.3 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 KPI46100.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.7 2 1 1 3 3 3 0 Helicase HerA, central domain AAA_28 PF13521.6 KPI46100.1 - 0.27 11.5 4.1 0.43 10.8 0.3 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KPI46100.1 - 0.33 10.5 1.4 2 8.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 KPI46100.1 - 1.1 9.3 3.3 3 7.9 1.4 2.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Coilin_N PF15862.5 KPI46100.1 - 2.3 8.0 8.6 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 Coilin N-terminus FAD_binding_2 PF00890.24 KPI46101.1 - 5.7e-47 160.7 1.3 1.5e-46 159.3 1.3 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KPI46101.1 - 4.9e-10 39.5 0.4 0.00054 19.7 0.2 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KPI46101.1 - 1.8e-09 36.8 0.0 0.0053 15.5 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 KPI46101.1 - 3.6e-05 23.1 1.0 0.0023 17.2 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KPI46101.1 - 5.4e-05 22.5 0.2 2.1 7.4 0.0 3.1 3 0 0 3 3 3 3 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KPI46101.1 - 7.4e-05 22.0 0.1 0.00025 20.2 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KPI46101.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KPI46101.1 - 0.00038 19.4 0.9 0.022 13.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KPI46101.1 - 0.017 15.1 0.1 0.089 12.8 0.1 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KPI46101.1 - 0.019 14.2 0.0 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KPI46101.1 - 0.037 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KPI46101.1 - 0.043 13.2 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Nudix_N_2 PF14803.6 KPI46102.1 - 0.094 12.7 2.0 3.4 7.7 0.3 2.3 2 0 0 2 2 2 0 Nudix N-terminal FAD-oxidase_C PF02913.19 KPI46104.1 - 4.8e-08 32.9 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain APG5 PF04106.12 KPI46105.1 - 5.2e-55 186.5 0.0 6.1e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 MFS_1 PF07690.16 KPI46106.1 - 1.1e-39 136.4 80.8 5.8e-33 114.3 49.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RPN1_C PF18051.1 KPI46107.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal NMO PF03060.15 KPI46108.1 - 2.1e-49 168.7 2.9 2.8e-49 168.3 2.9 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KPI46108.1 - 5.5e-07 28.9 3.8 1e-06 28.0 2.8 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Radial_spoke_3 PF06098.11 KPI46108.1 - 0.0031 16.8 0.1 0.0043 16.4 0.1 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 FMN_dh PF01070.18 KPI46108.1 - 0.018 14.0 3.6 0.033 13.2 3.6 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 KPI46108.1 - 0.08 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DNA_pol_E_B PF04042.16 KPI46109.1 - 5.4e-43 146.8 0.0 7.2e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KPI46109.1 - 5.2e-40 136.5 0.0 1e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain PepX_C PF08530.10 KPI46110.1 - 9.6e-21 74.7 0.7 2.2e-20 73.6 0.7 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KPI46110.1 - 2.7e-18 66.5 0.4 2.9e-10 40.2 0.1 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phialophora_attae-ASM129925v1/GCA_001299255.1_ASM129925v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phialophora_attae-ASM129925v1/GCA_001299255.1_ASM129925v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phialophora_attae-ASM129925v1/GCA_001299255.1_ASM129925v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phialophora_attae-ASM129925v1/GCA_001299255.1_ASM129925v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 03:26:56 2019 # [ok]